-- dump date   	20140619_095114
-- class       	Genbank::Feature
-- table       	feature
-- table       	main
-- field 1	id
-- field 2	type
-- field 3	name
-- field 4	contig
-- field 5	start_pos
-- field 6	end_pos
-- field 7	strand
-- field 8	description
-- field 9	chrom_position
-- field 10	organism
-- field 11	GeneID
-- header
-- id	type	name	contig	start_pos	end_pos	strand	description	chrom_position	organism	GeneID
393115000001	SEQ_END	SEQ_END	NC_008245.1	1892616	1892616	DR	NC_008245.1; contig end	1892616..1892616	Francisella tularensis subsp. tularensis FSC198	<NULL_VALUE>
YP_666215.1	CDS	dnaA	NC_008245.1	1	1521	D	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein	1..1521	Francisella tularensis subsp. tularensis FSC198	4199350
YP_666216.1	CDS	dnaN	NC_008245.1	1558	2661	D	Similar to DP3B_ECOLI (P00583) DNA polymerase III,beta chain from E. coli (366 aa). FASTA opt: 826 Z-score: 955.1 E(): 2.6e-45 Smith-Waterman score: 826; 35.230 identity in 369 aa overlap; DNA polymerase III subunit beta	1558..2661	Francisella tularensis subsp. tularensis FSC198	4199357
YP_666217.1	CDS	isftu1	NC_008245.1	3204	3988	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(3204..3662,3662..3988))	Francisella tularensis subsp. tularensis FSC198	4199614
YP_666218.1	CDS	FTF0006	NC_008245.1	4661	5869	D	Similar to Q9ZE69 Proline/betaine transporter (PROP1) from Rickettsia prowazekii (418 aa). FASTA: opt: 605 Z-score: 665.8 E(): 3.4e-29 Smith-Waterman score: 605; 28.293 identity in 410 aa overlap ORF ftt0006; MFS superfamily proline/ betaine transporter	4661..5869	Francisella tularensis subsp. tularensis FSC198	4200573
YP_666219.1	CDS	aspS	NC_008245.1	6044	7822	D	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase	6044..7822	Francisella tularensis subsp. tularensis FSC198	4199691
YP_666220.1	CDS	FTF0013c	NC_008245.1	11450	12232	R	ORF ftt0013c; lipoprotein	complement(11450..12232)	Francisella tularensis subsp. tularensis FSC198	4200578
YP_666221.1	CDS	FTF0014c	NC_008245.1	12472	12870	R	ORF ftt0014c; hypothetical protein	complement(12472..12870)	Francisella tularensis subsp. tularensis FSC198	4200579
YP_666222.1	CDS	purB	NC_008245.1	13198	14496	D	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase	13198..14496	Francisella tularensis subsp. tularensis FSC198	4199115
YP_666223.1	CDS	FTF0016	NC_008245.1	14530	15108	D	ORF ftt0016; hypothetical protein	14530..15108	Francisella tularensis subsp. tularensis FSC198	4200580
YP_666224.1	CDS	FTF0017	NC_008245.1	15195	16736	D	Similar to Q8PAK3 Toxin secretion ABC transporter ATP-binding protein from Xanthomonas axonopodis (563 aa). FASTA: opt: 454 Z-score: 516.4 E(): 7.1e-21 Smith-Waterman score: 454; 24.395identity in 496 aa overlap ORF ftt0017; hypothetical protein	15195..16736	Francisella tularensis subsp. tularensis FSC198	4200581
YP_666225.1	CDS	FTF0018	NC_008245.1	16744	17817	D	Similar to Q8PMA5 RND efflux membrane fusion protein from Xanthomonas axonopodis (354 aa). FASTA: opt: 851 Z-score: 971.0 E(): 3.4e-46 Smith-Waterman score: 851; 37.846 identity in 325 aa overlap ORF ftt0018; secretion protein	16744..17817	Francisella tularensis subsp. tularensis FSC198	4200582
YP_666226.1	CDS	gatC	NC_008245.1	17900	18181	D	Similar to Q82T57 Glu-tRNAGln amidotransferase C subunit from Nitrosomonas europaea (95 aa). FASTA:i opt: 188 Z-score: 259.9 E(): 1.4e-06 Smith-Waterman score: 188; 31.818 identity in 88 aa overlap; Glu-tRNAGln amidotransferase C subunit	17900..18181	Francisella tularensis subsp. tularensis FSC198	4199275
YP_666227.1	CDS	gatA	NC_008245.1	18190	19635	D	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A	18190..19635	Francisella tularensis subsp. tularensis FSC198	4199273
YP_666228.1	CDS	gatB	NC_008245.1	19638	21059	D	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B	19638..21059	Francisella tularensis subsp. tularensis FSC198	4199274
YP_666229.1	CDS	FTF0022	NC_008245.1	21074	21481	D	ORF ftt0022; hypothetical protein	21074..21481	Francisella tularensis subsp. tularensis FSC198	4200583
YP_666230.1	CDS	FTF0023c	NC_008245.1	21497	22378	R	Similar to Q9F7Y6 Glycerophospholipid-cholesterol acyltransferase from Aeromonas salmonicida (336 aa). FASTA: opt: 367 Z-score: 437.4 E(): 1.8e-16 Smith-Waterman score: 407; 30.183 identity in 328 aa overlap ORF ftt0023c; lipase/acyltransferase	complement(21497..22378)	Francisella tularensis subsp. tularensis FSC198	4200584
YP_666231.1	CDS	FTF0024c	NC_008245.1	22646	22990	R	ORF ftt0024c; hypothetical protein	complement(22646..22990)	Francisella tularensis subsp. tularensis FSC198	4200585
YP_666232.1	CDS	FTF0025c	NC_008245.1	23038	24567	R	ORF ftt0025c; hypothetical protein	complement(23038..24567)	Francisella tularensis subsp. tularensis FSC198	4200586
YP_666233.1	CDS	FTF0026c	NC_008245.1	24652	25842	R	Similar to Q9HWP5 Probable MFS transporter from Pseudomonas aeruginosa (402 aa). FASTA: opt: 568 Z-score: 586.0 E(): 9.5e-25 Smith-Waterman score: 568; 26.425 identity in 386 aa overlap ORF ftt0026c; hypothetical protein	complement(24652..25842)	Francisella tularensis subsp. tularensis FSC198	4200587
YP_666234.1	CDS	lysA1	NC_008245.1	25858	27111	R	Similar to DCDA_BACSU (P23630) Diaminopimelate decarboxylase from Bacillus subtilis (441 aa). FASTA: opt: 437 Z-score: 538.0 E(): 4.5e-22 Smith-Waterman score: 437; 27.295 identity in 414 aa overlap; diaminopimelate decarboxylase	complement(25858..27111)	Francisella tularensis subsp. tularensis FSC198	4199652
YP_666235.1	CDS	FTF0028c	NC_008245.1	27104	28366	R	Similar to YCEE_ECOLI (P25744) Hypothetical transport protein yce from E. coli (408 aa). FASTA: opt: 364 Z-score: 408.7 E(): 7.1e-15 Smith-Waterman score: 450; 26.582 identity in 395 aa overlap ORF ftt0028c; hypothetical protein	complement(27104..28366)	Francisella tularensis subsp. tularensis FSC198	4200588
YP_666236.1	CDS	FTF0029c	NC_008245.1	28373	30292	R	Similar to AAO89973 (Q83EA5) FrgA protein from Coxiella burnetii (528 aa). FASTA: opt: 1047 Z-score: 1237.4 E(): 4.9e-61 Smith-Waterman score: 1053; 34.051 identity in 511 aa overlap ORF ftt0029c; hypothetical protein	complement(28373..30292)	Francisella tularensis subsp. tularensis FSC198	4200589
YP_666237.1	CDS	fur	NC_008245.1	30545	30967	R	Similar to FUR_ECOLI (P06975) Ferric uptake regulation protein from E. coli (148 aa). FASTA: opt: 396 Z-score: 515.7 E(): 7.8e-21 Smith-Waterman score: 396; 40.714 identity in 140 aa overlap; ferric uptake regulation protein	complement(30545..30967)	Francisella tularensis subsp. tularensis FSC198	4199202
YP_666238.1	CDS	nuoA	NC_008245.1	31176	31574	D	Similar to Q9A6X0 NADH dehydrogenase I, A subunit from Caulobacter crescentus (125 aa). FASTA: opt: 398 Z-score: 508.1 E(): 2.1e-20 Smith-Waterman score: 398; 46.565 identity in 131 aa overlap; NADH dehydrogenase I subunit A	31176..31574	Francisella tularensis subsp. tularensis FSC198	4200245
YP_666239.1	CDS	nuoB	NC_008245.1	31565	32041	D	The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B	31565..32041	Francisella tularensis subsp. tularensis FSC198	4200246
YP_666240.1	CDS	nuoC	NC_008245.1	32038	32688	D	Similar to NUOC_NEIMB (Q9K1C1) NADH-quinone oxidoreductase chain from Neisseria meningitidis (197 aa). FASTA: opt: 516 Z-score: 659.3 E(): 7.8e-29 Smith-Waterman score: 568; 44.286identity in 210 aa overlap; NADH dehydrogenase I	32038..32688	Francisella tularensis subsp. tularensis FSC198	4200247
YP_666241.1	CDS	nuoD	NC_008245.1	32710	33963	D	Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D	32710..33963	Francisella tularensis subsp. tularensis FSC198	4200248
YP_666242.1	CDS	nuoE	NC_008245.1	33973	34461	D	Similar to Q83BQ9 NADH dehydrogenase I, E subunit from Xanthomonas campestris (174 aa). FASTA: opt: 528 Z-score: 689.7 E(): 1.6e-30 Smith-Waterman score: 528; 52.318 identity in 151 aa overlap; NADH dehydrogenase I subunit E	33973..34461	Francisella tularensis subsp. tularensis FSC198	4200249
YP_666243.1	CDS	nuoF	NC_008245.1	34468	35742	D	Similar to Q83BR0 NADH dehydrogenase I, F subunit from Coxiella burnetti (422 aa). FASTA: opt: 1851 Z-score: 2306.0 E(): 1.5e-120 Smith-Waterman score: 1851; 61.848 identity in 422 aa overlap; NADH dehydrogenase I subunit F	34468..35742	Francisella tularensis subsp. tularensis FSC198	4200745
YP_666244.1	CDS	nuoG	NC_008245.1	35760	38126	D	Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G	35760..38126	Francisella tularensis subsp. tularensis FSC198	4200746
YP_666245.1	CDS	nuoH	NC_008245.1	38128	39138	D	Similar to Q83BR2 NADH dehydrogenase I, H subunit from Coxiella burnetii (340 aa). FASTA: opt: 1510 Z-score: 1695.3 E(): 1.5e-86 Smith-Waterman score: 1510; 60.843 identity in 332 aa overlap; NADH dehydrogenase I subunit H	38128..39138	Francisella tularensis subsp. tularensis FSC198	4200747
YP_666246.1	CDS	nuoI	NC_008245.1	39152	39640	D	Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I	39152..39640	Francisella tularensis subsp. tularensis FSC198	4200748
YP_666247.1	CDS	nuoJ	NC_008245.1	39645	40250	D	Similar to Q9K1B2 NADH dehydrogenase I, J subunit from Neisseria meningitidis (223 aa). FASTA: opt: 387 Z-score: 452.6 E(): 2.6e-17 Smith-Waterman score: 387; 38.191 identity in 199 aa overlap; NADH dehydrogenase I subunit J	39645..40250	Francisella tularensis subsp. tularensis FSC198	4200749
YP_666248.1	CDS	nuoK	NC_008245.1	40228	40560	D	Similar to Q9A6Y6 NADH dehydrogenase I, K subunit from Caulobacter crescentus (101 aa). FASTA: opt: 300 Z-score: 405.7 E(): 1e-14 Smith-Waterman score: 300; 43.000 identity in 100 aa overlap; NADH dehydrogenase I subunit K	40228..40560	Francisella tularensis subsp. tularensis FSC198	4200750
YP_666249.1	CDS	nuoL	NC_008245.1	40570	42579	D	Similar to Q83BR6 NADH dehydrogenase I, L subunit from Coxiella burnetii (653 aa). FASTA: opt: 1934 Z-score: 2065.6 E(): 3.6e-107 Smith-Waterman score: 2090; 50.760 identity in 658 aa overlap; NADH dehydrogenase I subunit L	40570..42579	Francisella tularensis subsp. tularensis FSC198	4200751
YP_666250.1	CDS	nuoM	NC_008245.1	42605	44194	D	Similar to Q83BR7 NADH dehydrogenase I, M subunit from Coxiella burnetii (506 aa). FASTA: opt: 1099 Z-score: 1147.9 E(): 4.8e-56 Smith-Waterman score: 1659; 47.228 identity in 523 aa overlap; NADH dehydrogenase I subunit M	42605..44194	Francisella tularensis subsp. tularensis FSC198	4200752
YP_666251.1	CDS	nuoN	NC_008245.1	44204	45661	D	Similar to Q83BR8 NADH dehydrogenase I, N subunit from Coxiella burnetii (482 aa). FASTA: opt: 1231 Z-score: 1222.9 E(): 3.2e-60 Smith-Waterman score: 1231; 39.914 identity in 466 aa overlap; NADH dehydrogenase I subunit N	44204..45661	Francisella tularensis subsp. tularensis FSC198	4200753
YP_666252.1	CDS	FTF0045	NC_008245.1	45737	45931	D	Similar to Q8DDC7 Conserved hypothetical protein from Vibrio vulnificus (83 aa). FASTA: opt: 165 Z-score: 224.7 E(): 0.00013 Smith-Waterman score: 165; 45.763 identity in 59 aa overlap ORF ftt0045; hypothetical protein	45737..45931	Francisella tularensis subsp. tularensis FSC198	4200590
YP_666253.1	CDS	hemE	NC_008245.1	47478	48512	D	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase	47478..48512	Francisella tularensis subsp. tularensis FSC198	4200374
YP_666254.1	CDS	FTF0048	NC_008245.1	48732	49190	D	Similar to Q88DV5 Conserved hypothetical protein from Pseudomonas putida (169 aa). FASTA: opt: 402 Z-score: 490.7 E(): 1.7e-19 Smith-Waterman score: 402; 43.243 identity in 148 aa overlap ORF ftt0048; hypothetical protein	48732..49190	Francisella tularensis subsp. tularensis FSC198	4199153
YP_666255.1	CDS	nusA	NC_008245.1	49208	50677	D	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA	49208..50677	Francisella tularensis subsp. tularensis FSC198	4200757
YP_666256.1	CDS	infB	NC_008245.1	50716	53256	D	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2	50716..53256	Francisella tularensis subsp. tularensis FSC198	4199610
YP_666257.1	CDS	rbfA	NC_008245.1	53259	53690	D	Similar to RBFA_ECOLI (P09170) Ribosome-binding factor A from E. coli (132 aa). FASTA: opt: 301 Z-score: 381.1 E(): 2.5e-13 Smith-Waterman score: 301; 41.935 identity in 124 aa overlap; ribosome-binding factor A	53259..53690	Francisella tularensis subsp. tularensis FSC198	4200596
YP_666258.1	CDS	hisS	NC_008245.1	53698	54963	D	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase	53698..54963	Francisella tularensis subsp. tularensis FSC198	4200195
YP_666259.1	CDS	FTF0053	NC_008245.1	54970	56268	D	Similar to AAO90449 (Q83D24) Major facilitator family transporter from Coxiella burnetii (437 aa). FASTA: opt: 908 Z-score: 1023.7 E(): 3.6e-49 Smith-Waterman score: 909; 36.603 identity in 418 aa overlap ORF ftt0053; major facilitator transporter	54970..56268	Francisella tularensis subsp. tularensis FSC198	4199154
YP_666260.1	CDS	FTF0054	NC_008245.1	56271	57338	D	Similar to YHCM_ECOLI (P46442) Hypothetical protein yhcM from E. coli (375 aa). FASTA: opt: 872 Z-score: 1033.2 E(): 1.2e-49 Smith-Waterman score: 898; 39.833 identity in 359 aa overlap ORF ftt0054; ATPase	56271..57338	Francisella tularensis subsp. tularensis FSC198	4199155
YP_666261.1	CDS	rluC	NC_008245.1	57331	58260	D	Similar to RLUC_ECOLI (P23851) Ribosomal large subunit pseudouridine synthase C from E. coli (319 aa). FASTA: opt: 791 Z-score: 972.5 E(): 2.8e-46 Smith-Waterman score: 791; 40.777 identity in 309 aa overlap; ribosomal large subunit pseudouridine synthase C	57331..58260	Francisella tularensis subsp. tularensis FSC198	4199222
YP_666262.1	CDS	FTF0056c	NC_008245.1	58262	59566	R	Similar to Q83D24 (Q83D24) Major facilitator family transporter from Coxiella burnetii (437 aa). FASTA: opt: 1028 Z-score: 1172.6 E(): 2e-57 Smith-Waterman score: 1036; 40.187 identity in 428 aa overlap ORF ftt0056c; major facilitator transporter	complement(58262..59566)	Francisella tularensis subsp. tularensis FSC198	4199156
YP_666263.1	CDS	FTF0057	NC_008245.1	59643	60074	D	ORF ftt0057; hypothetical protein	59643..60074	Francisella tularensis subsp. tularensis FSC198	4199157
YP_666264.1	CDS	atpB	NC_008245.1	60127	60918	D	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A	60127..60918	Francisella tularensis subsp. tularensis FSC198	4199693
YP_666265.1	CDS	atpE	NC_008245.1	60969	61274	D	produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C	60969..61274	Francisella tularensis subsp. tularensis FSC198	4199696
YP_666266.1	CDS	atpF	NC_008245.1	61320	61790	D	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B	61320..61790	Francisella tularensis subsp. tularensis FSC198	4199697
YP_666267.1	CDS	atpH	NC_008245.1	61810	62334	D	Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta	61810..62334	Francisella tularensis subsp. tularensis FSC198	4199699
YP_666268.1	CDS	atpA	NC_008245.1	62353	63894	D	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha	62353..63894	Francisella tularensis subsp. tularensis FSC198	4199692
YP_666269.1	CDS	atpG	NC_008245.1	63909	64805	D	produces ATP from ADP in the presence of a proton gradient across the membrane; the gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma	63909..64805	Francisella tularensis subsp. tularensis FSC198	4199698
YP_666270.1	CDS	atpD	NC_008245.1	64815	66191	D	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta	64815..66191	Francisella tularensis subsp. tularensis FSC198	4199695
YP_666271.1	CDS	atpC	NC_008245.1	66204	66641	D	produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon	66204..66641	Francisella tularensis subsp. tularensis FSC198	4199694
YP_666272.1	CDS	FTF0066	NC_008245.1	66852	69695	D	ORF ftt0066; hypothetical protein	66852..69695	Francisella tularensis subsp. tularensis FSC198	4199158
YP_666273.1	CDS	FTF0067c	NC_008245.1	69712	70041	R	Similar to Q8D879 Glutaredoxin-related protein from Vibrio vulnificus (112 aa). FASTA: opt: 485 Z-score: 630.6 E(): 2.8e-27 Smith-Waterman score: 485; 65.306 identity in 98 aa overlap ORF ftt0067c; glutaredoxin-like protein	complement(69712..70041)	Francisella tularensis subsp. tularensis FSC198	4199159
YP_666274.1	CDS	sodB	NC_008245.1	70177	70755	D	Fe; Similar to SODF_ECOLI (P09157) Superoxide dismutase [Fe] from E. coli (192 aa). FASTA: opt: 896 Z-score: 1143.2 E(): 8.8e-56 Smith-Waterman score: 896; 66.316 identity in 190 aa overlap; superoxide dismutase	70177..70755	Francisella tularensis subsp. tularensis FSC198	4199077
YP_666275.1	CDS	FTF0069c	NC_008245.1	70763	70948	R	ORF ftt0069c; hypothetical protein	complement(70763..70948)	Francisella tularensis subsp. tularensis FSC198	4199160
YP_666276.1	CDS	ampG	NC_008245.1	70960	72225	R	Similar to AMPG_ECOLI (P36670) AmpG protein from E. coli (491 aa). FASTA: opt: 996 Z-score: 1121.1 E(): 1.5e-54 Smith-Waterman score: 996; 38.614 identity in 404 aa overlap; major facilitator superfamily transporter	complement(70960..72225)	Francisella tularensis subsp. tularensis FSC198	4199422
YP_666277.1	CDS	gltA	NC_008245.1	72314	73588	R	Similar to CISY_PSEAE (P14165) Citrate synthase from Pseudomonas aeruginosa (428 aa). FASTA: opt: 1540 Z-score: 1956.3 E(): 4.5e-101 Smith-Waterman score: 1540; 57.353 identity in 408 aa overlap; citrate synthase	complement(72314..73588)	Francisella tularensis subsp. tularensis FSC198	4199799
YP_666278.1	CDS	sdhC	NC_008245.1	73831	74304	D	Similar to Q884A1 Succinate dehydrogenase,cytochrome b556 subunit from Pseudomonas syringae (124 aa). FASTA: opt: 332 Z-score: 413.6 E(): 3.8e-15 Smith-Waterman score: 332; 39.844identity in 128 aa overlap; succinate dehydrogenase, cytochrome b556	73831..74304	Francisella tularensis subsp. tularensis FSC198	4200731
YP_666279.1	CDS	sdhD	NC_008245.1	74280	74648	D	Similar to Q88FA6 Succinate dehydrogenase,hydrophobic membrane anchor protein from Pseudomonas putida (122 aa). FASTA: opt: 242 Z-score: 306.8 E(): 3.4e-09 Smith-Waterman score: 242; 34.677 identity in 124 aa overlap; succinate dehydrogenase hydrophobic membrane anchor protein	74280..74648	Francisella tularensis subsp. tularensis FSC198	4200732
YP_666280.1	CDS	sdhA	NC_008245.1	74661	76454	D	Similar to Q9I3D5 Succinate dehydrogenase (A subunit) from Pseudomonas aeruginosa (590 aa). FASTA: opt: 2468 Z-score: 2874.7 E(): 3.2e-152 Smith-Waterman score: 2468; 61.139 identity in 597 aa overlap; succinate dehydrogenase, catalytic and NAD/flavoprotein subunit	74661..76454	Francisella tularensis subsp. tularensis FSC198	4200729
YP_666281.1	CDS	sdhB	NC_008245.1	76472	77173	D	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit	76472..77173	Francisella tularensis subsp. tularensis FSC198	4200730
YP_666282.1	CDS	sucA	NC_008245.1	77191	80016	D	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component	77191..80016	Francisella tularensis subsp. tularensis FSC198	4199087
YP_666283.1	CDS	sucB	NC_008245.1	80042	81511	D	Similar to Q8EFN9 2-oxoglutarate dehydrogenase,E2 component, dihydrolipoamide succinyltransferase from Shewanella oneidensis (395 aa). FASTA: opt: 1379 Z-score: 1563.0 E(): 3.6e-79 Smith-Waterman score: 1379; 55.949 identity in 395 aa overlap; dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex	80042..81511	Francisella tularensis subsp. tularensis FSC198	4199088
YP_666284.1	CDS	apt	NC_008245.1	81551	82078	D	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase	81551..82078	Francisella tularensis subsp. tularensis FSC198	4199429
YP_666285.1	CDS	glmM	NC_008245.1	82089	83420	D	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase	82089..83420	Francisella tularensis subsp. tularensis FSC198	4199855
YP_666286.1	CDS	tpiA	NC_008245.1	83423	84184	D	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase	83423..84184	Francisella tularensis subsp. tularensis FSC198	4199859
YP_666287.1	CDS	secG	NC_008245.1	84172	84525	D	Similar to Q9KU83 Preprotein translocase, SecG subunit from Vibrio cholerae (111 aa). FASTA: opt: 283 Z-score: 369.6 E(): 1.1e-12 Smith-Waterman score: 289; 45.299identity in 117 aa overlap. Together with SecE and SecY forming an integral membrane complex.; preprotein translocase subunit SecG	84172..84525	Francisella tularensis subsp. tularensis FSC198	4200739
YP_666288.1	CDS	FTF0083	NC_008245.1	85736	86212	D	ORF ftt0083; hypothetical protein	85736..86212	Francisella tularensis subsp. tularensis FSC198	4199162
YP_666289.1	CDS	hemN	NC_008245.1	86209	87351	R	Similar to Q87V87 Oxygen-independent coproporphyrinogen III oxidase,putative,from Pseudomonas syringae (404 aa). FASTA: opt: 1156 Z-score: 1386.6 E(): 2.4e-69 Smith-Waterman score: 1156; 46.791 identity in 374 aa overlap; oxygen-independent coproporphyrinogen III oxidase	complement(86209..87351)	Francisella tularensis subsp. tularensis FSC198	4200379
YP_666290.1	CDS	FTF0085c	NC_008245.1	87356	87733	R	Similar to YWCD_BACSU P39602 Hypothetical protein ywcD from Bacillus subtilis (127 aa). FASTA: opt: 162 Z-score: 223.9 E(): 0.00013 Smith-Waterman score: 162; 26.667 identity in 120 aa overlap ORF ftt0085c; hypothetical protein	complement(87356..87733)	Francisella tularensis subsp. tularensis FSC198	4199163
YP_666291.1	CDS	FTF0086	NC_008245.1	87803	88681	D	Similar to Q9I078 Hypothetical protein PA2765 from Pseudomonas aeruginosa (299 aa). FASTA: opt: 656 Z-score: 793.3 E(): 2.4e-36 Smith-Waterman score: 656; 36.678 identity in 289 aa overlap ORF ftt0086; hypothetical protein	87803..88681	Francisella tularensis subsp. tularensis FSC198	4199164
YP_666292.1	CDS	acnA	NC_008245.1	88786	91599	D	Catalyzes the conversion of citrate to isocitrate; aconitate hydratase	88786..91599	Francisella tularensis subsp. tularensis FSC198	4199752
YP_666293.1	CDS	pilT	NC_008245.1	91694	92722	D	Similar to Q8EBZ4 Twitching motility protein PilT from Shewanella oneidensis (345 aa). FASTA: opt: 1226 Z-score: 1391.3 E(): 1.3e-69 Smith-Waterman score: 1226; 57.186 identity in 334 aa overlap Required for pili retraction probably by filament disassembly. Homologous to pilB but which has the opposite effect. Unique to type IV pili.; Type IV pili nucleotide-binding protein	91694..92722	Francisella tularensis subsp. tularensis FSC198	4199733
YP_666294.1	CDS	FTF0090c	NC_008245.1	93784	94230	R	Similar to Q87GR3 Hypothetical protein from Vibrio parahaemolyticus (148 aa). FASTA: opt: 160 Z-score: 212.3 E(): 0.00057 Smith-Waterman score: 160; 29.104 identity in 134 aa overlap ORF ftt0090c; hypothetical protein	complement(93784..94230)	Francisella tularensis subsp. tularensis FSC198	4199166
YP_666295.1	CDS	appB	NC_008245.1	94241	95203	R	Similar to Q87H27 Cytochrome BD2, subunit II from Vibrio parahaemolyticus (335 aa). FASTA: opt: 573 Z-score: 669.5 E(): 1.9e-29 Smith-Waterman score: 750; 34.743 identity in 331 aa overlap; cytochrome oxidase bd-II subunit II	complement(94241..95203)	Francisella tularensis subsp. tularensis FSC198	4199427
YP_666296.1	CDS	FTF0093	NC_008245.1	96819	97700	D	Similar to Q8FFI5 Hypothetical protein yfcH from E. coli (297 aa). FASTA: opt: 498 Z-score: 611.0 E(): 3.8e-26 Smith-Waterman score: 498; 32.673 identity in 303 aa overlap ORF ftt0093; hypothetical protein	96819..97700	Francisella tularensis subsp. tularensis FSC198	4199167
YP_666297.1	CDS	qseC	NC_008245.1	97697	99124	R	Similar to AAO90737 (Q83CA0) Sensor histidine kinase from Coxiella burnetii (478 aa). FASTA: opt: 653 Z-score: 752.8 E(): 4.9e-34 Smith-Waterman score: 677; 29.083 identity in 447 aa overlap Sensory histidine kinase in two-component regulatory system with QseB, regulates flagella and motility by quorum sensing in E. coli,according to Q8X524; sensor histidine kinase	complement(97697..99124)	Francisella tularensis subsp. tularensis FSC198	4200593
YP_666298.1	CDS	FTF0095	NC_008245.1	99240	100196	D	ORF ftt0095; hypothetical protein	99240..100196	Francisella tularensis subsp. tularensis FSC198	4199168
YP_666299.1	CDS	FTF0096	NC_008245.1	100438	101478	D	ORF ftt0096; hypothetical protein	100438..101478	Francisella tularensis subsp. tularensis FSC198	4199169
YP_666300.1	CDS	FTF0097	NC_008245.1	101612	102157	D	ORF ftt0097; hypothetical protein	101612..102157	Francisella tularensis subsp. tularensis FSC198	4199170
YP_666301.1	CDS	isftu1	NC_008245.1	102231	103015	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(102231..102689,102689..103015))	Francisella tularensis subsp. tularensis FSC198	4199616
YP_666302.1	CDS	isftu2	NC_008245.1	103117	103860	D	ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa).; transposase	103117..103860	Francisella tularensis subsp. tularensis FSC198	4200189
YP_666303.1	CDS	FTF0101	NC_008245.1	104530	105543	D	Similar to Y402_RICPR (Q9ZDC9) Hypothetical protein RP402 from Rickettsia prowazekii (317 aa). FASTA: opt: 431 Z-score: 518.0 E(): 5.9e-21 Smith-Waterman score: 432; 28.909 identity in 339 aa overlap ORF ftt0101; hypothetical protein	104530..105543	Francisella tularensis subsp. tularensis FSC198	4200535
YP_666304.1	CDS	FTF0103c	NC_008245.1	106988	107569	R	ORF ftt0103c; hypothetical protein	complement(106988..107569)	Francisella tularensis subsp. tularensis FSC198	4200537
YP_666305.1	CDS	FTF0104c	NC_008245.1	107814	109091	R	Similar to Q83DX6 Major facilitator family transporter from Coxiella burnetii (421 aa). FASTA: opt: 995 Z-score: 1049.4 E(): 1.5e-50 Smith-Waterman score: 995; 39.066identity in 407 aa overlap ORF ftt0104c; major facilitator transporter	complement(107814..109091)	Francisella tularensis subsp. tularensis FSC198	4200538
YP_666306.1	CDS	FTF0105c	NC_008245.1	109223	112336	R	Similar to AAO90606 (Q83CM1) Transporter,AcrB/AcrD/AcrF family from Coxiella burnetii (1019 aa). FASTA: opt: 2662 Z-score: 2840.6 E(): 2.3e-150 Smith-Waterman score: 3071; 45.171identity in 1025 aa overlap ORF ftt0105c; AcrB/AcrD/AcrF family transporter	complement(109223..112336)	Francisella tularensis subsp. tularensis FSC198	4200539
YP_666307.1	CDS	FTF0106c	NC_008245.1	112336	113709	R	Similar to Q83CM0 Efflux transporter, RND family,MFP subunit from Coxiella burnetti (380 aa). FASTA: opt: 732 Z-score: 824.0 E(): 5.2e-38 Smith-Waterman score: 781; 34.748identity in 377 aa overlap ORF ftt0106c; RND efflux transporter	complement(112336..113709)	Francisella tularensis subsp. tularensis FSC198	4200540
YP_666308.1	CDS	dsbB	NC_008245.1	113722	114213	R	Similar to DSBB_NEIMB (Q9JYC6) Disulfide bond formation protein B (disuphide oxidoreductase) from Neisseria meningitidis (162 aa). FASTA: opt: 171 Z-score: 223.1 E(): 0.00014 Smith-Waterman score: 171; 27.344 identity in 128 aa overlap; disulfide bond formation protein	complement(113722..114213)	Francisella tularensis subsp. tularensis FSC198	4199360
YP_666309.1	CDS	cca	NC_008245.1	114253	115335	R	catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase	complement(114253..115335)	Francisella tularensis subsp. tularensis FSC198	4200318
YP_666310.1	CDS	msbA	NC_008245.1	115440	117269	D	lipid A transport protein, ABC transporter,ATP-binding and membrane protein. Similar to Q47908 ValA from Francisella novicida strain U112 (572 aa). FASTA: opt: 3334 Z-score: 3684.8 E(): 2.4e-197 Smith-Waterman score: 3334; 97.810 identity in 548 aa overlap (54-601:13-559). Similar to MSBA_HAEIN (P44407) Lipid A export ATP-binding protein from Haemophilus influenzae (587 aa). FASTA: opt: 1570 Z-score: 1735.1 E(): 9.4e-89 Smith-Waterman score: 1570; 41.913identity in 575 aa overlap.; lipid A transport protein ABC transporter ATP-binding protein/permease	115440..117269	Francisella tularensis subsp. tularensis FSC198	4199856
YP_666311.1	CDS	lpxK	NC_008245.1	117275	118243	D	transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase	117275..118243	Francisella tularensis subsp. tularensis FSC198	4199650
YP_666312.1	CDS	polA	NC_008245.1	118339	121032	D	Similar to AAO91288 (Q83AT5) DNA polymerase I from Coxiella burnetii (895 aa). FASTA: opt: 2961 Z-score: 3329.8 E(): 1.4e-177 Smith-Waterman score: 2961; 52.058 identity in 899 aa overlap; DNA polymerase I	118339..121032	Francisella tularensis subsp. tularensis FSC198	4199736
YP_666313.1	CDS	FTF0112	NC_008245.1	121052	121828	D	type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase	121052..121828	Francisella tularensis subsp. tularensis FSC198	4200541
YP_666314.1	CDS	deoB	NC_008245.1	121833	123077	D	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase	121833..123077	Francisella tularensis subsp. tularensis FSC198	4199344
YP_666315.1	CDS	deoC	NC_008245.1	123040	123801	D	Similar to AAP95774 (Q7VMS9) Deoxyribose-phosphate aldolase from Haemophilus ducreyi (258 aa). FASTA: opt: 632 Z-score: 764.1 E(): 1.1e-34 Smith-Waterman score: 632; 42.857 identity in 245 aa overlap; deoxyribose-phosphate aldolase	123040..123801	Francisella tularensis subsp. tularensis FSC198	4199345
YP_666316.1	CDS	nupC1	NC_008245.1	123791	124990	D	Similar to AAP07626 (Q81I17) Nucleoside permease nupC from Bacillus cereus (392 aa). FASTA: opt: 1236 Z-score: 1430.7 E(): 7.7e-72 Smith-Waterman score: 1236; 49.246 identity in 398 aa overlap Paralog of FTF0116; nucleoside permease NUP family protein	123791..124990	Francisella tularensis subsp. tularensis FSC198	4200754
YP_666317.1	CDS	nupC1	NC_008245.1	125009	126211	D	Similar to (AAP07626) Q81I17 Nucleoside permease nupC from Bacillus cereus (392 aa). FASTA: opt: 1351 Z-score: 1549.9 E(): 1.9e-78 Smith-Waterman score: 1351; 52.381 identity in 399 aa overlap Paralog of FTF0115; nucleoside permease NUP family protein	125009..126211	Francisella tularensis subsp. tularensis FSC198	4200755
YP_666318.1	CDS	tmk	NC_008245.1	126224	126853	D	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase	126224..126853	Francisella tularensis subsp. tularensis FSC198	4200756
YP_666319.1	CDS	prfC	NC_008245.1	126915	128492	D	stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3	126915..128492	Francisella tularensis subsp. tularensis FSC198	4199939
YP_666320.1	CDS	FTF0119	NC_008245.1	128567	129883	D	ORF ftt0119; hypothetical protein	128567..129883	Francisella tularensis subsp. tularensis FSC198	4200542
YP_666321.1	CDS	ftsY	NC_008245.1	129880	130911	D	Similar to Q9I6C1 Signal recognition particle receptor FtsY from Pseudomonas aeruginosa (455 aa). FASTA: opt: 1262 Z-score: 1403.4 E(): 2.8e-70 Smith-Waterman score: 1262; 61.935identity in 310 aa overlap; signal recognition particle receptor FtsY	129880..130911	Francisella tularensis subsp. tularensis FSC198	4199198
YP_666322.1	CDS	uvrD	NC_008245.1	131002	133224	D	Similar to Q88C31 DNA helicase II from Pseudomonas putida (728 aa). FASTA: opt: 1880 Z-score: 2129.9 E(): 9.6e-111 Smith-Waterman score: 2083; 45.867 identity in 750 aa overlap; DNA helicase II	131002..133224	Francisella tularensis subsp. tularensis FSC198	4200136
YP_666323.1	CDS	oppD	NC_008245.1	136649	137617	D	Similar to Q8D8A2 Oligopeptide ABC transporter,ATP-binding protein D from Vibrio vulnificus (324 aa). FASTA: opt: 1202 Z-score: 1353.8 E(): 1.6e-67 Smith-Waterman score: 1202; 56.270 identity in 311 aa overlap; oligopeptide transporter, subunit D, ABC transporter ATP-binding protein	136649..137617	Francisella tularensis subsp. tularensis FSC198	4200084
YP_666324.1	CDS	oppF	NC_008245.1	137618	138592	D	Similar to OPPF_HAEIN (P45051) Oligopeptide transport ATP-binding oppF from Haemophilus influenzae (332 aa). FASTA: opt: 1227 Z-score: 1398.5 E(): 5.3e-70 Smith-Waterman score: 1227; 56.790 identity in 324 aa overlap; oligopeptide transporter, subunit F, ABC transporter ATP-binding protein	137618..138592	Francisella tularensis subsp. tularensis FSC198	4200085
YP_666325.1	CDS	FTF0127c	NC_008245.1	138596	139798	R	Similar to Q83CF6 Major facilitator family transporter from Coxiella burnetii (443 aa). FASTA: opt: 488 Z-score: 542.0 E(): 2.7e-22 Smith-Waterman score: 490; 27.621identity in 391 aa overlap ORF ftt0127c; major facilitator transporter	complement(138596..139798)	Francisella tularensis subsp. tularensis FSC198	4200543
YP_666326.1	CDS	FTF0128	NC_008245.1	139932	140513	D	ORF ftt0128; hypothetical protein	139932..140513	Francisella tularensis subsp. tularensis FSC198	4200544
YP_666327.1	CDS	FTF0129	NC_008245.1	140657	141925	D	Similar to Q83BM0 (Q83BM0) Major facilitator family transporter from Coxiella burnetii (428 aa). FASTA: opt: 497 Z-score: 533.3 E(): 8.2e-22 Smith-Waterman score: 529; 26.355 identity in 406 aa overlap ORF ftt0129; major facilitator transporter	140657..141925	Francisella tularensis subsp. tularensis FSC198	4200545
YP_666328.1	CDS	glpK	NC_008245.1	141982	143490	D	Similar to GLPK_THETN (Q8R8J4) Glycerol kinase from Thermoanaerobacter tengcongensis (497 aa). FASTA: opt: 2233 Z-score: 2691.0 E(): 5.3e-142 Smith-Waterman score: 2233; 66.333 identity in 499 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein; glycerol kinase	141982..143490	Francisella tularensis subsp. tularensis FSC198	4199796
YP_666329.1	CDS	isftu1	NC_008245.1	143583	144367	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(143583..144041,144041..144367))	Francisella tularensis subsp. tularensis FSC198	4199617
YP_666330.1	CDS	glpA	NC_008245.1	144683	146215	D	Similar to O51259 Glycerol-3-phosphate dehydrogenase, anaerobic, from Borrelia burgdorferii (527 aa). FASTA: opt: 1330 Z-score: 1506.9 E(): 4.8e-76 Smith-Waterman score: 1330; 43.333 identity in 510 aa overlap; anaerobic glycerol-3-phosphate dehydrogenase	144683..146215	Francisella tularensis subsp. tularensis FSC198	4199793
YP_666331.1	CDS	glpF	NC_008245.1	146225	146989	D	Similar to CAD75967 (Q7UMF0) Probable glycerol uptake facilitator protein from Rhodopirelulla baltica (271 aa). FASTA: opt: 796 Z-score: 888.1 E(): 1.4e-41 Smith-Waterman score: 796; 50.209 identity in 239 aa overlap; glycerol uptake facilitator protein	146225..146989	Francisella tularensis subsp. tularensis FSC198	4199795
YP_666332.1	CDS	FTF0134	NC_008245.1	146993	147706	D	ORF ftt0134; hypothetical protein	146993..147706	Francisella tularensis subsp. tularensis FSC198	4200546
YP_666333.1	CDS	FTF0136	NC_008245.1	148181	149596	D	Similar to AAQ00172 (Q7VBG7) DNA helicase related to phage enzyme from Prochlorococcus marinus (479 aa) FASTA: opt: 386 Z-score: 446.1 E(): 5.9e-17 Smith-Waterman score: 386; 26.681 identity in 476 aa overlap ORF ftt0136; helicase	148181..149596	Francisella tularensis subsp. tularensis FSC198	4200548
YP_666334.1	CDS	tufA	NC_008245.1	150061	151245	D	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu	150061..151245	Francisella tularensis subsp. tularensis FSC198	4198974
YP_666335.1	CDS	secE	NC_008245.1	151437	151907	D	forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE	151437..151907	Francisella tularensis subsp. tularensis FSC198	4200737
YP_666336.1	CDS	nusG	NC_008245.1	151923	152456	D	Similar to NUSG_VIBVU (Q8DD25) Transcription antitermination protein nusG from Vibrio vulnificus (181 aa). FASTA: opt: 687 Z-score: 868.9 E(): 1.7e-40 Smith-Waterman score: 687; 58.621 identity in 174 aa overlap; transcription antitermination protein nusG	151923..152456	Francisella tularensis subsp. tularensis FSC198	4200759
YP_666337.1	CDS	rplK	NC_008245.1	152525	152959	D	binds directly to 23S ribosomal RNA; 50S ribosomal protein L11	152525..152959	Francisella tularensis subsp. tularensis FSC198	4200781
YP_666338.1	CDS	rplA	NC_008245.1	152962	153657	D	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1	152962..153657	Francisella tularensis subsp. tularensis FSC198	4200773
YP_666339.1	CDS	rplJ	NC_008245.1	153827	154345	D	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10	153827..154345	Francisella tularensis subsp. tularensis FSC198	4200780
YP_666340.1	CDS	rplL	NC_008245.1	154408	154785	D	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12	154408..154785	Francisella tularensis subsp. tularensis FSC198	4200782
YP_666341.1	CDS	rpoB	NC_008245.1	154939	159015	D	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta	154939..159015	Francisella tularensis subsp. tularensis FSC198	4200328
YP_666342.1	CDS	rpoC	NC_008245.1	159077	163330	D	Similar to Q9AAU1 (Q9AAU1) DNA-directed RNA polymerase, beta subunit from Caulobacter crescentus (1396 aa). FASTA: opt: 5089 Z-score: 5550.7 E(): 0 Smith-Waterman score: 5089; 56.626identity in 1381 aa overlap; DNA-directed RNA polymerase subunit beta	159077..163330	Francisella tularensis subsp. tularensis FSC198	4200329
YP_666343.1	CDS	FTF0146	NC_008245.1	163433	163669	D	ORF ftt0146; hypothetical protein	163433..163669	Francisella tularensis subsp. tularensis FSC198	4200549
YP_666344.1	CDS	gcp	NC_008245.1	163669	164679	D	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease	163669..164679	Francisella tularensis subsp. tularensis FSC198	4199276
YP_666345.1	CDS	FTF0148	NC_008245.1	164793	165959	D	Similar to Q27437 Stearoyl-CoA desaturase from Amblyomma americanum (317 aa). FASTA: opt: 653 Z-score: 747.5 E(): 9.6e-34 Smith-Waterman score: 653; 36.897 identity in 290 aa overlap ORF ftt0148; fatty acid desaturase	164793..165959	Francisella tularensis subsp. tularensis FSC198	4200550
YP_666346.1	CDS	metK	NC_008245.1	166171	167331	R	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase	complement(166171..167331)	Francisella tularensis subsp. tularensis FSC198	4199839
YP_666347.1	CDS	rpsP	NC_008245.1	167625	167873	D	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16	167625..167873	Francisella tularensis subsp. tularensis FSC198	4198954
YP_666348.1	CDS	rimM	NC_008245.1	167916	168425	D	Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM	167916..168425	Francisella tularensis subsp. tularensis FSC198	4199220
YP_666349.1	CDS	trmD	NC_008245.1	168822	169586	D	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase	168822..169586	Francisella tularensis subsp. tularensis FSC198	4199863
YP_666350.1	CDS	rplS	NC_008245.1	169586	169933	D	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19	169586..169933	Francisella tularensis subsp. tularensis FSC198	4198995
YP_666351.1	CDS	xerD	NC_008245.1	170099	170977	D	Similar to Q7ZAJ8 (Q7ZAJ8) Integrase/recombinase XerD from Shewanella oneidensis (300 aa). FASTA: opt: 1039 Z-score: 1285.0 E(): 1.1e-63 Smith-Waterman score: 1039; 52.414 identity in 290 aa overlap; integrase/recombinase	170099..170977	Francisella tularensis subsp. tularensis FSC198	4200694
YP_666352.1	CDS	FTF0155	NC_008245.1	171094	171945	D	Similar to Q87HU0 Putative oxidoreductase iron/ascorbate from Vibrio parahaemolyticus (279 aa). FASTA: opt: 944 Z-score: 1155.0 E(): 1.9e-56 Smith-Waterman score: 944; 49.110 identity in 281 aa overlap ORF ftt0155; oxidoreductase iron/ascorbate family protein	171094..171945	Francisella tularensis subsp. tularensis FSC198	4200551
YP_666353.1	CDS	FTF0156	NC_008245.1	171950	172534	D	Similar to Q83EI5 Acid phosphatase, class B from Coxiella burnetti (221 aa). FASTA: opt: 326 Z-score: 430.9 E(): 4.1e-16 Smith-Waterman score: 326; 32.642identity in 193 aa overlap ORF ftt0156; acid phosphatase	171950..172534	Francisella tularensis subsp. tularensis FSC198	4200630
YP_666354.1	CDS	FTF0157c	NC_008245.1	172531	173415	R	Similar to Q8XMR0 Probable lic-1 operon protein from Clostridium perfringens (322 aa). FASTA: opt: 370 Z-score: 410.4 E(): 5.7e-15 Smith-Waterman score: 396; 30.492 identity in 305 aa overlap ORF ftt0157c; licB-like transmembrane protein	complement(172531..173415)	Francisella tularensis subsp. tularensis FSC198	4200631
YP_666355.1	CDS	FTF0158c	NC_008245.1	173547	174155	R	ORF ftt0158c; hypothetical protein	complement(173547..174155)	Francisella tularensis subsp. tularensis FSC198	4200632
YP_666356.1	CDS	FTF0159c	NC_008245.1	174232	175053	R	ORF ftt0159c; hypothetical protein	complement(174232..175053)	Francisella tularensis subsp. tularensis FSC198	4200633
YP_666357.1	CDS	nudH	NC_008245.1	175216	175683	D	hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase	175216..175683	Francisella tularensis subsp. tularensis FSC198	4200244
YP_666358.1	CDS	FTF0161c	NC_008245.1	175693	176319	R	Similar to Q8FXE8 PAP2 family protein from Brucella suis (325 aa). FASTA: opt: 314 Z-score: 375.8 E(): 4.8e-13 Smith-Waterman score: 314; 31.915identity in 188 aa overlap ORF ftt0161c; PAP2 family protein	complement(175693..176319)	Francisella tularensis subsp. tularensis FSC198	4200634
YP_666359.1	CDS	ampD	NC_008245.1	176393	176917	D	Similar to Q88PQ9 N-acetyl-anhydromuramyl-L-alanine amidase ampD from Pseudomonas putida (190 aa). FASTA: opt: 623 Z-score: 809.4 E(): 3.4e-37 Smith-Waterman score: 623; 52.000 identity in 175 aa overlap; N-acetyl-anhydromuranmyl-L-alanine amidase	176393..176917	Francisella tularensis subsp. tularensis FSC198	4199421
YP_666360.1	CDS	parE	NC_008245.1	176975	178858	R	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B	complement(176975..178858)	Francisella tularensis subsp. tularensis FSC198	4200096
YP_666361.1	CDS	FTF0164c	NC_008245.1	178948	180129	R	Similar to Q9KRK6 Multidrug resistance protein from Vibrio cholerae (401 aa). FASTA: opt: 579 Z-score: 614.0 E(): 2.6e-26 Smith-Waterman score: 579; 28.989identity in 376 aa overlap ORF ftt0164c; eflux protein	complement(178948..180129)	Francisella tularensis subsp. tularensis FSC198	4200635
YP_666362.1	CDS	FTF0165c	NC_008245.1	180129	181499	R	Similar to Q88PJ4 Conserved hypothetical protein from Pseudomonas putida (380 aa). FASTA: opt: 644 Z-score: 755.3 E(): 3.5e-34 Smith-Waterman score: 646; 29.268 identity in 369 aa overlap ORF ftt0165c; lipoprotein	complement(180129..181499)	Francisella tularensis subsp. tularensis FSC198	4200636
YP_666363.1	CDS	FTF0166c	NC_008245.1	181502	182158	R	Similar to Q8FF57 Hypothetical protein yfgM from E. coli (206 aa). FASTA: opt: 155 Z-score: 188.7 E(): 0.012 Smith-Waterman score: 188; 27.778 identity in 198 aa overlap ORF ftt0166c; hypothetical protein	complement(181502..182158)	Francisella tularensis subsp. tularensis FSC198	4200637
YP_666364.1	CDS	hemA	NC_008245.1	182339	183589	D	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase	182339..183589	Francisella tularensis subsp. tularensis FSC198	4200370
YP_666365.1	CDS	prfA	NC_008245.1	183590	184675	D	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1	183590..184675	Francisella tularensis subsp. tularensis FSC198	4199937
YP_666366.1	CDS	FTF0169	NC_008245.1	184668	185522	D	ORF ftt0169; hemK protein	184668..185522	Francisella tularensis subsp. tularensis FSC198	4200638
YP_666367.1	CDS	isftu1	NC_008245.1	186007	186791	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(186007..186333,186333..186791)	Francisella tularensis subsp. tularensis FSC198	4199618
YP_666368.1	CDS	FTF0174	NC_008245.1	188232	188801	D	Similar to Q83A22 Hypothetical protein from Coxiella burnetti (192 aa). FASTA: opt: 440 Z-score: 543.8 E(): 2.1e-22 Smith-Waterman score: 440; 37.634 identity in 186 aa overlap ORF ftt0174; YggT family protein	188232..188801	Francisella tularensis subsp. tularensis FSC198	4200642
YP_666369.1	CDS	FTF0175c	NC_008245.1	188795	189577	R	Similar to AAO80856 (Q836Q5) ABC transporter,ATP-binding protein (269 aa). FASTA: opt: 738 Z-score: 809.5 E(): 3.1e-37 Smith-Waterman score: 738; 43.137 identity in 255 aa overlap missing 90 aa at C-terminus ORF ftt0175c; ABC transporter ATP-binding protein	complement(188795..189577)	Francisella tularensis subsp. tularensis FSC198	4200643
YP_666370.1	CDS	FTF0177c	NC_008245.1	191761	192186	R	Similar to Q88IP2 Acetyltransferase, GNAT family from Pseudomonas putida (364 aa). FASTA: opt: 250 Z-score: 324.7 E(): 3.1e-10 Smith-Waterman score: 250; 34.559 identity in 136 aa overlap ORF ftt0177c; acetyltransferase	complement(191761..192186)	Francisella tularensis subsp. tularensis FSC198	4200645
YP_666371.1	CDS	rimK	NC_008245.1	192173	193642	R	Similar to Q9KPN3 Ribosomal protein S6 modification protein-related protein from Vibrio cholerae (483 aa). FASTA: opt: 1367 Z-score: 1648.7 E(): 6.1e-84 Smith-Waterman score: 1367; 43.149 identity in 489 aa overlap; 30S ribosomal protein S6	complement(192173..193642)	Francisella tularensis subsp. tularensis FSC198	4199219
YP_666372.1	CDS	FTF0180	NC_008245.1	195923	196813	D	Similar to Q8DDF5 1-acyl-sn-glycerol-3-phosphate acyltransferase from Vibrio vulnificus (271 aa). FASTA: opt: 749 Z-score: 902.5 E(): 2e-42 Smith-Waterman score: 749; 40.370 identity in 270 aa overlap ORF ftt0180; putative acyltransferase	195923..196813	Francisella tularensis subsp. tularensis FSC198	4200647
YP_666373.1	CDS	FTF0181c	NC_008245.1	197210	197746	R	Similar to Q9X885 Putative small integral membrane protein from Streptomyces coelicolor (167 aa). FASTA: opt: 262 Z-score: 342.1 E(): 3.6e-11 Smith-Waterman score: 262; 30.723 identity in 166 aa overlap ORF ftt0181c; hypothetical protein	complement(197210..197746)	Francisella tularensis subsp. tularensis FSC198	4200783
YP_666374.1	CDS	FTF0182c	NC_008245.1	197844	198386	R	Similar to Q8D257 YrdC protein from Wigglesworthia glossinidia (194 aa). FASTA: opt: 374 Z-score: 473.0 E(): 1.9e-18 Smith-Waterman score: 374; 39.130 identity in 184 aa overlap ORF ftt0182c; Sua5/YciO/YrdC family protein	complement(197844..198386)	Francisella tularensis subsp. tularensis FSC198	4200784
YP_666375.1	CDS	rpsA	NC_008245.1	198503	200173	R	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1	complement(198503..200173)	Francisella tularensis subsp. tularensis FSC198	4200333
YP_666376.1	CDS	FTF0184	NC_008245.1	200321	200782	D	Similar to Q83DS3 Zinc-binding domain protein from Coxiella burnetii (142 aa). FASTA: opt: 473 Z-score: 642.4 E(): 6.8e-28 Smith-Waterman score: 473; 52.817 identity in 142 aa overlap ORF ftt0184; zinc-binding domain-containing protein	200321..200782	Francisella tularensis subsp. tularensis FSC198	4200785
YP_666377.1	CDS	ddlB	NC_008245.1	200786	201676	D	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A	200786..201676	Francisella tularensis subsp. tularensis FSC198	4199530
YP_666378.1	CDS	ftsQ	NC_008245.1	201673	202356	D	Similar to Q83F15 Cell division protein FtsQ from Coxiella burnetii (243 aa). FASTA: opt: 291 Z-score: 355.4 E(): 6.6e-12 Smith-Waterman score: 291; 23.176 identity in 233 aa overlap; cell division protein FtsQ	201673..202356	Francisella tularensis subsp. tularensis FSC198	4199196
YP_666379.1	CDS	ftsA	NC_008245.1	202458	203720	D	Similar to Q87WY9 Cell division protein FtsA from Pseuodomonas syringae (418 aa). FASTA: opt: 992 Z-score: 1194.6 E(): 1.2e-58 Smith-Waterman score: 992; 37.621 identity in 412 aa overlap; cell division protein FtsA	202458..203720	Francisella tularensis subsp. tularensis FSC198	4199192
YP_666380.1	CDS	ftsZ	NC_008245.1	203764	204909	D	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ	203764..204909	Francisella tularensis subsp. tularensis FSC198	4199199
YP_666381.1	CDS	lpxC	NC_008245.1	204932	205792	D	zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase	204932..205792	Francisella tularensis subsp. tularensis FSC198	4199571
YP_666382.1	CDS	dnaX	NC_008245.1	205806	207446	R	Similar to Q8DB24 DNA polymerase III, gamma/tau subunits from Vibrio vulnificus (734 aa). FASTA: opt: 1193 Z-score: 1334.5 E(): 1.9e-66 Smith-Waterman score: 1193; 44.893 identity in 421 aa overlap; DNA polymerase III subunit gamma and tau	complement(205806..207446)	Francisella tularensis subsp. tularensis FSC198	4199359
YP_666383.1	CDS	prfB	NC_008245.1	207719	208696	D	Similar to RF2_HAEIN (P43918) Peptide chain release factor 2 from Haemophilus influenzae (365 aa). FASTA: opt: 1542 Z-score: 1839.9 E(): 1.4e-94 Smith-Waterman score: 1542; 68.405 identity in 326 aa overlap; peptide chain release factor 2	207719..208696	Francisella tularensis subsp. tularensis FSC198	4199938
YP_666384.1	CDS	lysU	NC_008245.1	208829	210559	D	Similar to SYK2_ECOLI (P14825) Lysyl-tRNA synthetase, heat inducible, from E. coli (504 aa). FASTA: opt: 2003 Z-score: 2242.9 E(): 4.9e-117 Smith-Waterman score: 2003; 61.066 identity in 488 aa overlap; lysyl-tRNA synthetase	208829..210559	Francisella tularensis subsp. tularensis FSC198	4199655
YP_666385.1	CDS	FTF0193c	NC_008245.1	210944	211486	R	Similar to Y208_VIBCH (Q9KVD8) Hypothetical protein VC0208 from Vibrio cholerae (162 aa). FASTA: opt: 414 Z-score: 528.5 E(): 1.5e-21 Smith-Waterman score: 414; 41.875 identity in 160 aa overlap ORF ftt0193c; hypothetical protein	complement(210944..211486)	Francisella tularensis subsp. tularensis FSC198	4200786
YP_666386.1	CDS	FTF0194c	NC_008245.1	211585	212457	R	Similar to Q8X898 Hypothetical 31.1 kDa protein (Hypothetical membrane protein) from E.coli (274 aa). FASTA: opt: 398 Z-score: 431.1 E(): 4e-16 Smith-Waterman score: 398; 26.429 identity in 280 aa overlap ORF ftt0194c; hypothetical protein	complement(211585..212457)	Francisella tularensis subsp. tularensis FSC198	4200787
YP_666387.1	CDS	FTF0195c	NC_008245.1	212466	214007	R	Similar to Q8IX91 L-glutaminase from Homo sapien (602 aa). FASTA: opt: 1441 Z-score: 1670.0 E(): 3.9e-85 Smith-Waterman score: 1441; 42.887 identity in 478 aa overlap ORF ftt0195c; L-glutaminase	complement(212466..214007)	Francisella tularensis subsp. tularensis FSC198	4200788
YP_666388.1	CDS	glnA	NC_008245.1	214089	215126	R	Similar to AAO90051 (Q83E31) Glutamine synthetase from Coxiella burnetti (359 aa). FASTA: opt: 1369 Z-score: 1705.1 E(): 4.4e-87 Smith-Waterman score: 1369; 59.226 identity in 336 aa overlap; glutamine synthetase	complement(214089..215126)	Francisella tularensis subsp. tularensis FSC198	4199789
YP_666389.1	CDS	holA	NC_008245.1	215246	216223	R	Similar to Q88DM9 DNA polymerase III, delta subunit from Pseudomonas putida (345 aa). FASTA: opt: 380 Z-score: 451.8 E(): 2.8e-17 Smith-Waterman score: 380; 28.707 identity in 317 aa overlap; DNA polymerase III subunit delta	complement(215246..216223)	Francisella tularensis subsp. tularensis FSC198	4200197
YP_666390.1	CDS	blc	NC_008245.1	216351	216827	D	Similar to Q8EGB4 Lipoprotein Blc from Shewenella oneidensis (177 aa). FASTA: opt: 620 Z-score: 813.1 E(): 2.1e-37 Smith-Waterman score: 620; 56.604 identity in 159 aa overlap; outer membrane lipoprotein	216351..216827	Francisella tularensis subsp. tularensis FSC198	4200311
YP_666391.1	CDS	FTF0199	NC_008245.1	216991	217824	D	ORF ftt0199; hypothetical protein	216991..217824	Francisella tularensis subsp. tularensis FSC198	4200789
YP_666392.1	CDS	FTF0200	NC_008245.1	217772	218389	D	ORF ftt0200; hypothetical protein	217772..218389	Francisella tularensis subsp. tularensis FSC198	4200790
YP_666393.1	CDS	isftu2	NC_008245.1	218963	219706	R	ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa).; transposase	complement(218963..219706)	Francisella tularensis subsp. tularensis FSC198	4200190
YP_666394.1	CDS	purH	NC_008245.1	220957	222504	R	involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	complement(220957..222504)	Francisella tularensis subsp. tularensis FSC198	4199119
YP_666395.1	CDS	purA	NC_008245.1	222681	223967	D	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase	222681..223967	Francisella tularensis subsp. tularensis FSC198	4199951
YP_666396.1	CDS	hpt	NC_008245.1	223971	224504	D	Similar to Q8R7L0 Hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcogenesis (181 aa). FASTA: opt: 509 Z-score: 658.7 E(): 8.5e-29 Smith-Waterman score: 509; 47.337 identity in 169 aa overlap; hypoxanthine-guanine phosphoribosyltransferase	223971..224504	Francisella tularensis subsp. tularensis FSC198	4200200
YP_666397.1	CDS	FTF0207c	NC_008245.1	225339	226181	R	Similar to Q8G5L3 Possible permease of ABC transporter system from Bifidobacterium longum (277 aa). FASTA: opt: 582 Z-score: 622.6 E(): 8.7e-27 Smith-Waterman score: 582; 38.372identity in 258 aa overlap ORF ftt0207c; ABC transporter permease	complement(225339..226181)	Francisella tularensis subsp. tularensis FSC198	4200793
YP_666398.1	CDS	FTF0208c	NC_008245.1	226123	226800	R	Similar to MNTB_BACSU (O34338) Manganese transport system ATP-binding protein mntB from Bacillus subtilis (250 aa). FASTA: opt: 365 Z-score: 426.7 E(): 7.1e-16 Smith-Waterman score: 365; 30.986 identity in 213 aa overlap ORF ftt0208c; ABC transporter ATP-binding protein	complement(226123..226800)	Francisella tularensis subsp. tularensis FSC198	4200794
YP_666399.1	CDS	FTF0209c	NC_008245.1	226802	227719	R	Similar to Q88TE8 ABC transporter substrate binding protein from Lactobacillus plantarum (297 aa). FASTA: opt: 555 Z-score: 628.8 E(): 3.9e-27 Smith-Waterman score: 555; 30.935identity in 278 aa overlap ORF ftt0209c; periplasmic solute binding family protein	complement(226802..227719)	Francisella tularensis subsp. tularensis FSC198	4200795
YP_666400.1	CDS	FTF0211c	NC_008245.1	229135	229599	R	Similar to Q9F6B1 Outer membrane lipoprotein Pcp from Edwardsiella tarda (155 aa). FASTA: opt: 294 Z-score: 329.0 E(): 2e-10 Smith-Waterman score: 294; 35.032 identity in 157 aa overlap ORF ftt0211c; outer membrane lipoprotein	complement(229135..229599)	Francisella tularensis subsp. tularensis FSC198	4200797
YP_666401.1	CDS	wrbA	NC_008245.1	229610	230206	R	Similar to Q9I509 Trp repressor binding protein WrbA from Pseudomonas aeruginosa (198 aa). FASTA: opt: 727 Z-score: 948.0 E(): 6.5e-45 Smith-Waterman score: 727; 54.974 identity in 191 aa overlap; trp repressor binding protein	complement(229610..230206)	Francisella tularensis subsp. tularensis FSC198	4200688
YP_666402.1	CDS	rbn	NC_008245.1	230213	231400	D	Similar to RBN_ECOLI (P32146) tRNA processing ribonuclease BN from E. coli (290 aa). FASTA: opt: 535 Z-score: 578.5 E(): 2.5e-24 Smith-Waterman score: 535; 33.813 identity in 278 aa overlap; tRNA processing ribonuclease BN	230213..231400	Francisella tularensis subsp. tularensis FSC198	4200597
YP_666403.1	CDS	FTF0214	NC_008245.1	231419	231976	D	Similar to Q9I2E6 Probable transporter from Pseudomonas aeruginosa (191 aa). FASTA: Q8PGT5 PnuC protein from Xanthomonas axonopodois (191 aa). FASTA: opt: 216 Z-score: 281.0 E(): 8.5e-08 Smith-Waterman score: 216; 27.072 identity in 181 aa overlap. Contains a frameshift in Schu S4 but intact in FSC 198; transporter	231419..231976	Francisella tularensis subsp. tularensis FSC198	4200798
YP_666404.1	CDS	priA	NC_008245.1	231990	234143	D	Similar to Q9KNQ3 Primosomal protein N` from Vibrio cholerae (734 aa). FASTA: opt: 1587 Z-score: 1770.8 E(): 9.7e-91 Smith-Waterman score: 1619; 37.823 identity in 735 aa overlap; primosomal protein N'	231990..234143	Francisella tularensis subsp. tularensis FSC198	4199940
YP_666405.1	CDS	isftu1	NC_008245.1	234273	235057	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(234273..234599,234599..235057)	Francisella tularensis subsp. tularensis FSC198	4199619
YP_666406.1	CDS	FTF0219c	NC_008245.1	235996	236991	R	Similar to Q81FW2 Low-affinity inorganic phosphate transport protein from Bacillus cereus (332 aa). FASTA: opt: 932 Z-score: 1065.7 E(): 1.8e-51 Smith-Waterman score: 932; 42.470 identity in 332 aa overlap ORF ftt0219c; phosphate transport protein	complement(235996..236991)	Francisella tularensis subsp. tularensis FSC198	4200343
YP_666407.1	CDS	FTF0220c	NC_008245.1	237009	237665	R	Similar to Q8XMV6 Hypothetical protein CPE0582 from Clostridium perfringens (210 aa). FASTA: opt: 207 Z-score: 248.6 E(): 5.9e-06 Smith-Waterman score: 207; 24.883 identity in 213 aa overlap ORF ftt0220c; hypothetical protein	complement(237009..237665)	Francisella tularensis subsp. tularensis FSC198	4200344
YP_666408.1	CDS	acpA	NC_008245.1	237902	239446	D	acid phosphatase	237902..239446	Francisella tularensis subsp. tularensis FSC198	4199753
YP_666409.1	CDS	ybgK	NC_008245.1	239453	240229	R	Similar to YBGK_HAEIN (P44298) Hypothetical protein HI1730 from Haemophilus influenzae (309 aa). FASTA: opt: 308 Z-score: 386.7 E(): 1.2e-13 Smith-Waterman score: 352; 32.453 identity in 265 aa overlap; hydrolase subunit	complement(239453..240229)	Francisella tularensis subsp. tularensis FSC198	4200702
YP_666410.1	CDS	ybgL	NC_008245.1	240271	240969	R	Similar to Y993_PYRAB (Q9V005) Hypothetical UPF0271 protein PYRAB09930 from Pyrococcus abyssi (255 aa). FASTA: opt: 430 Z-score: 541.0 E(): 3e-22 Smith-Waterman score: 430; 35.294 identity in 238 aa overlap; LamB/YcsF family protein	complement(240271..240969)	Francisella tularensis subsp. tularensis FSC198	4200703
YP_666411.1	CDS	isftu1	NC_008245.1	242754	243538	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(242754..243212,243212..243538))	Francisella tularensis subsp. tularensis FSC198	4199620
YP_666412.1	CDS	FTF0227c	NC_008245.1	243562	243756	R	ORF ftt0227c; hypothetical protein	complement(243562..243756)	Francisella tularensis subsp. tularensis FSC198	4200347
YP_666413.1	CDS	orn	NC_008245.1	243791	244327	R	3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease	complement(243791..244327)	Francisella tularensis subsp. tularensis FSC198	4200086
YP_666414.1	CDS	efp	NC_008245.1	244330	244899	R	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P	complement(244330..244899)	Francisella tularensis subsp. tularensis FSC198	4199670
YP_666415.1	CDS	FTF0230c	NC_008245.1	244939	245346	R	Similar to Q87B50 Type IV pilin from Xylella fastidiosa (142 aa). FASTA: opt: 224 Z-score: 300.3 E(): 7.8e-09 Smith-Waterman score: 224; 32.090 identity in 134 aa overlap The pili fiber building block protein has a highly distinct primary structure; a short positively charged leader sequence, and a highly conserved and highly hydrophobic amino-terminal domain which forms the core of the pilus fiber; A variety of studies suggest that the invariant glycine (G) at -1 is required for prepilin cleavage and assembly and that the glutamate (E) at + 5 is essential for assembly and efficient N-terminal methylation but not cleavage. The region near the carboxy terminus is often hydrophilic and is stabilized by one or two disulfide bridges that may be involved in recognition of receptors. The genes with these characteristics are usually termed pilA, pilE, pilV, pilW, pilX and FimU. (Mattick John S.. 'Type IV Pili and twitching motility'. Annu. Rev. Microbiol. 2002. 56:289-314.) This protein has all the characteristics described above. ORF ftt0230c; Type IV pili fiber building block protein	complement(244939..245346)	Francisella tularensis subsp. tularensis FSC198	4200348
YP_666416.1	CDS	htrB	NC_008245.1	245359	246282	R	Similar to HTRB_ECOLI (P24187) Lipid A biosynthesis lauroyl acyltransferase from E. coli (306 aa). FASTA: opt: 542 Z-score: 697.7 E(): 5.7e-31 Smith-Waterman score: 542; 32.895 identity in 304 aa overlap (8-307:14-306) n.b.Paralog of FTF0232c; acyltransferase	complement(245359..246282)	Francisella tularensis subsp. tularensis FSC198	4200649
YP_666417.1	CDS	ddg	NC_008245.1	246343	247242	R	Similar to Q8ZNA3 (Q8ZNA3) Cold shock-induced palmitoleoyl transferase from Salmonella typhimurium (306 aa). FASTA: opt: 629 Z-score: 782.5 E(): 1.1e-35 Smith-Waterman score: 629; 36.755 identity in 302 aa overlap Paralog of FTF0231c; acyltransferase	complement(246343..247242)	Francisella tularensis subsp. tularensis FSC198	4199529
YP_666418.1	CDS	yidC	NC_008245.1	247249	248904	R	Similar to 60IM_COXBU (P45650) 60 kDa inner-membrane protein homolog from Coxiella burnetti (566 aa). FASTA: opt: 1434 Z-score: 1537.8 E(): 8.4e-78 Smith-Waterman score: 1434; 41.815 identity in 562 aa overlap; inner-membrane protein	complement(247249..248904)	Francisella tularensis subsp. tularensis FSC198	4199108
YP_666419.1	CDS	FTF0234c	NC_008245.1	248913	249125	R	Similar to Q8RHA5 Hypothetical protein FN0003 from Fusobacterium nucleatum (82 aa). FASTA: opt: 273 Z-score: 406.9 E(): 8.2e-15 Smith-Waterman score: 273; 53.623 identity in 69 aa overlap ORF ftt0234c; hypothetical protein	complement(248913..249125)	Francisella tularensis subsp. tularensis FSC198	4200349
YP_666420.1	CDS	rnpA	NC_008245.1	249137	249538	R	Similar to RNPA_VIBCH (Q9KVY2) Ribonuclease P protein component from Vibrio cholerae (118 aa). FASTA: opt: 189 Z-score: 256.8 E(): 2.1e-06 Smith-Waterman score: 189; 35.870 identity in 92 aa overlap; ribonuclease P protein component	complement(249137..249538)	Francisella tularensis subsp. tularensis FSC198	4200768
YP_666421.1	CDS	rpmH	NC_008245.1	249480	249614	R	in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34	complement(249480..249614)	Francisella tularensis subsp. tularensis FSC198	4199008
YP_666422.1	CDS	FTF0237c	NC_008245.1	249706	250164	R	ORF ftt0237c; hypothetical protein	complement(249706..250164)	Francisella tularensis subsp. tularensis FSC198	4200350
YP_666423.1	CDS	aroE1	NC_008245.1	250291	251064	D	Similar to AROE_VIBVU (Q8DDD4) Shikimate 5-dehydrogenase from Vibrio vulnificus (277 aa). FASTA: opt: 567 Z-score: 672.1 E(): 1.5e-29 Smith-Waterman score: 567; 37.984 identity in 258 aa overlap; shikimate 5-dehydrogenase	250291..251064	Francisella tularensis subsp. tularensis FSC198	4199435
YP_666424.1	CDS	murC	NC_008245.1	251131	252486	D	Similar to Q9F1M9 MurC from Shewanella violacae (494 aa). FASTA: opt: 1010 Z-score: 1212.3 E(): 1.2e-59 Smith-Waterman score: 1010; 36.761 identity in 457 aa overlap; UDP-N-acetylmuramate--L-alanine ligase	251131..252486	Francisella tularensis subsp. tularensis FSC198	4200106
YP_666425.1	CDS	FTF0240	NC_008245.1	252479	253351	D	Similar to Q87SH3 Conserved hypothetical protein from Vibrio parahaemolyticus (287 aa). FASTA: opt: 744 Z-score: 882.7 E(): 2.8e-41 Smith-Waterman score: 744; 46.996 identity in 283 aa overlap ORF ftt0240; tetrapyrrole methyltransferase family protein	252479..253351	Francisella tularensis subsp. tularensis FSC198	4200351
YP_666426.1	CDS	FTF0241c	NC_008245.1	253362	253832	R	ORF ftt0241c; hypothetical protein	complement(253362..253832)	Francisella tularensis subsp. tularensis FSC198	4200352
YP_666427.1	CDS	FTF0242	NC_008245.1	254172	254735	D	Similar to Q83DS9 Hypothetical protein CBU0616 from Coxiella burnetii (196 aa). FASTA: opt: 376 Z-score: 484.1 E(): 4.5e-19 Smith-Waterman score: 376; 37.634 identity in 186 aa overlap ORF ftt0242; hypothetical protein	254172..254735	Francisella tularensis subsp. tularensis FSC198	4200353
YP_666428.1	CDS	FTF0243	NC_008245.1	254808	255587	D	weak similarity to M. musculus protein,1700056O17 Rik protein (233 aa) ORF ftt0243; hypothetical protein	254808..255587	Francisella tularensis subsp. tularensis FSC198	4200354
YP_666429.1	CDS	FTF0244	NC_008245.1	255571	258312	D	Similar to Q8R5Z3 DNA/RNA helicase (DEAD/DEAH box family) from Fusobacterium nucleatum (942 aa). FASTA: opt: 2318 Z-score: 2654.5 E(): 5.8e-140 Smith-Waterman score: 2473; 45.087 identity in 916 aa overlap ORF ftt0244; DNA/RNA helicase	255571..258312	Francisella tularensis subsp. tularensis FSC198	4200355
YP_666430.1	CDS	usp	NC_008245.1	258388	259224	D	Similar to Q8PWX4 Universal stress protein from Methanosarcina maizae (323 aa). FASTA: opt: 347 Z-score: 418.2 E(): 2.1e-15 Smith-Waterman score: 347; 31.849 identity in 292 aa overlap; universal stress protein	258388..259224	Francisella tularensis subsp. tularensis FSC198	4198986
YP_666431.1	CDS	isftu1	NC_008245.1	259584	260368	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(259584..259910,259910..260368)	Francisella tularensis subsp. tularensis FSC198	4199621
YP_666432.1	CDS	FTF0248	NC_008245.1	260538	260909	D	ORF ftt0248; hypothetical protein	260538..260909	Francisella tularensis subsp. tularensis FSC198	4200357
YP_666433.1	CDS	feoB	NC_008245.1	261010	263253	D	Similar to Q8ZJH5 Ferrous iron transport protein B from Yersinia pestis (771 aa). FASTA: opt: 1928 Z-score: 2034.7 E(): 1.9e-105 Smith-Waterman score: 2307; 45.396 identity in 771 aa overlap; ferrous iron transport protein	261010..263253	Francisella tularensis subsp. tularensis FSC198	4199409
YP_666434.1	CDS	ppdK	NC_008245.1	264065	266713	D	catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase	264065..266713	Francisella tularensis subsp. tularensis FSC198	4199933
YP_666435.1	CDS	ilvE	NC_008245.1	267113	268000	D	Similar to Q8Y1X0 Probable branched-chain amino acid aminotransferase protein from Ralstonia solanacearum (309 aa). FASTA: opt: 706 Z-score: 903.1 E(): 2.1e-42 Smith-Waterman score: 706; 39.931 identity in 288 aa overlap; branched-chain amino acid aminotransferase	267113..268000	Francisella tularensis subsp. tularensis FSC198	4200665
YP_666436.1	CDS	leuA	NC_008245.1	268011	269384	D	Similar to Q9C5X5 2-isopropylmalate synthase from Arabidopsis thaliana (503 aa). FASTA: opt: 493 Z-score: 601.2 E(): 1.4e-25 Smith-Waterman score: 635; 31.373 identity in 408 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein; 2-isopropylmalate synthase	268011..269384	Francisella tularensis subsp. tularensis FSC198	4199513
YP_666437.1	CDS	isftu1	NC_008245.1	269481	270265	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(269481..269939,269939..270265))	Francisella tularensis subsp. tularensis FSC198	4199622
YP_666438.1	CDS	FTF0254c	NC_008245.1	270408	270779	R	ORF ftt0254c; hypothetical protein	complement(270408..270779)	Francisella tularensis subsp. tularensis FSC198	4200358
YP_666439.1	CDS	FTF0255c	NC_008245.1	270772	271713	R	ORF ftt0255c; hypothetical protein	complement(270772..271713)	Francisella tularensis subsp. tularensis FSC198	4200359
YP_666440.1	CDS	FTF0256c	NC_008245.1	272050	273018	R	Similar to Q87T79 Putative lipopolysaccharide A protein from Vibrio parahaemolyticus (311 aa). FASTA: opt: 835 Z-score: 996.3 E(): 1.3e-47 Smith-Waterman score: 910; 43.671 identity in 316 aa overlap ORF ftt0256c; lipopolysaccharide protein	complement(272050..273018)	Francisella tularensis subsp. tularensis FSC198	4200360
YP_666441.1	CDS	FTF0257	NC_008245.1	273207	275063	D	Similar to Q8YNW1 Ribonuclease II family protein from Anabaena sp. (686 aa). FASTA: opt: 557 Z-score: 649.1 E(): 2.9e-28 Smith-Waterman score: 763; 28.290 identity in 661 aa overlap ORF ftt0257; ribonuclease II family protein	273207..275063	Francisella tularensis subsp. tularensis FSC198	4200361
YP_666442.1	CDS	FTF0258	NC_008245.1	275394	276062	D	Similar to Q83AC9 Carboxylesterase/phospholipase family protein from Coxiella burnetii (200 aa). FASTA: opt: 599 Z-score: 736.0 E(): 4.2e-33 Smith-Waterman score: 599; 45.813 identity in 203 aa overlap ORF ftt0258; carboxylesterase/phospholipase family protein	275394..276062	Francisella tularensis subsp. tularensis FSC198	4200362
YP_666443.1	CDS	hemC	NC_008245.1	276059	276961	D	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase	276059..276961	Francisella tularensis subsp. tularensis FSC198	4200372
YP_666444.1	CDS	crcB	NC_008245.1	276962	277354	D	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB	276962..277354	Francisella tularensis subsp. tularensis FSC198	4200275
YP_666445.1	CDS	FTF0261	NC_008245.1	277351	277758	D	The predicted signal peptide are in conflict with the membrane lipoprotein lipid attachment site ORF ftt0261; hypothetical protein	277351..277758	Francisella tularensis subsp. tularensis FSC198	4200401
YP_666446.1	CDS	FTF0262	NC_008245.1	277898	278035	D	The predicted signal peptide and the membrane lipoprotein lipid attachment site are in conflict with each other ORF ftt0262; lipoprotein	277898..278035	Francisella tularensis subsp. tularensis FSC198	4200402
YP_666447.1	CDS	FTF0263	NC_008245.1	278088	278468	D	ORF ftt0263; hypothetical protein	278088..278468	Francisella tularensis subsp. tularensis FSC198	4200403
YP_666448.1	CDS	FTF0264c	NC_008245.1	278465	278638	R	Similar to Q8Y1X1 Hypothetical protein RSc0566 from Ralstonia solancearum (65 aa). FASTA: opt: 160 Z-score: 236.6 E(): 2.5e-05 Smith-Waterman score: 160; 50.000 identity in 36 aa overlap ORF ftt0264c; hypothetical protein	complement(278465..278638)	Francisella tularensis subsp. tularensis FSC198	4200404
YP_666449.1	CDS	FTF0265	NC_008245.1	278767	280566	D	Similar to Q83AV7 ABC transporter,permease protein from Coxiella burnetii (581 aa). FASTA: opt: 976 Z-score: 1115.9 E(): 2.9e-54 Smith-Waterman score: 1738; 45.318 identity in 598 aa overlap ORF ftt0265; ABC transporter membrane protein	278767..280566	Francisella tularensis subsp. tularensis FSC198	4200405
YP_666450.1	CDS	FTF0266	NC_008245.1	280585	281901	D	Similar to Q83AV8 ABC transporter, ATP-binding protein from Coxiella burnetii (432 aa). FASTA: opt: 1556 Z-score: 1713.5 E(): 1.5e-87 Smith-Waterman score: 1556; 54.673 identity in 428 aa overlap ORF ftt0266; ABC transporter ATP-binding protein	280585..281901	Francisella tularensis subsp. tularensis FSC198	4200406
YP_666451.1	CDS	FTF0267	NC_008245.1	282026	283144	D	ORF ftt0267; hypothetical protein	282026..283144	Francisella tularensis subsp. tularensis FSC198	4200407
YP_666452.1	CDS	FTF0268	NC_008245.1	283238	285124	D	Similar to Q88MV1 Sodium/hydrogen exchanger family protein from Pseudomonas putida (601 aa). FASTA: opt: 1318 Z-score: 1419.4 E(): 3.6e-71 Smith-Waterman score: 1318; 37.993 identity in 608 aa overlap ORF ftt0268; Sodium/hydrogen exchanger (antiporter) family protein	283238..285124	Francisella tularensis subsp. tularensis FSC198	4200408
YP_666453.1	CDS	FTF0269	NC_008245.1	285109	285648	D	Similar to Q8EKP8 Carbonic anhydrase,family 3 from Shewanella oneidensis (182 aa). FASTA: opt: 639 Z-score: 840.8 E(): 6.1e-39 Smith-Waterman score: 639; 50.000 identity in 178 aa overlap ORF ftt0269; carbonic anhydrase	285109..285648	Francisella tularensis subsp. tularensis FSC198	4200409
YP_666454.1	CDS	lolB	NC_008245.1	285599	286234	D	Similar to Q83AQ2 Outer membrane lipoprotein LolB,putative from Coxiella burnetii (210 aa). FASTA: opt: 395 Z-score: 508.7 E(): 1.9e-20 Smith-Waterman score: 395; 33.668 identity in 199 aa overlap; lipoprotein releasing system, subunit B, outer membrane lipoprotein	285599..286234	Francisella tularensis subsp. tularensis FSC198	4199559
YP_666455.1	CDS	ipk	NC_008245.1	286222	287049	D	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	286222..287049	Francisella tularensis subsp. tularensis FSC198	4199301
YP_666456.1	CDS	FTF0272	NC_008245.1	287238	287558	D	ORF ftt0272; hypothetical protein	287238..287558	Francisella tularensis subsp. tularensis FSC198	4200410
YP_666457.1	CDS	isftu1	NC_008245.1	287582	288366	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(287582..287908,287908..288366)	Francisella tularensis subsp. tularensis FSC198	4199623
YP_666458.1	CDS	FTF0274	NC_008245.1	288480	288698	D	ORF ftt0274; hypothetical protein	288480..288698	Francisella tularensis subsp. tularensis FSC198	4200411
YP_666459.1	CDS	FTF0277c	NC_008245.1	290443	290541	R	Similar to Q937K9 YbgT protein from Erwinia chrysanthemi (38 aa). FASTA: opt: 81 Z-score: 153.9 E(): 1 Smith-Waterman score: 81; 42.857 identity in 28 aa overlap ORF ftt0277c; hypothetical protein	complement(290443..290541)	Francisella tularensis subsp. tularensis FSC198	4200414
YP_666460.1	CDS	cydB	NC_008245.1	290557	291750	R	Similar to AAO69749 (Q8XGM0) Cytochrome d ubiquinol oxidase subunit II from Salmonella typhi (379 aa). FASTA: opt: 645 Z-score: 711.2 E(): 1e-31 Smith-Waterman score: 1022; 40.506identity in 395 aa overlap; cytochrome d terminal oxidase, polypeptide subunit II	complement(290557..291750)	Francisella tularensis subsp. tularensis FSC198	4200283
YP_666461.1	CDS	cydA	NC_008245.1	291761	293539	R	Similar to AAP96534 (Q7VKT6) Cytochrome D ubiquinol oxidase, subunit I from Haemophilus ducreyi (516 aa). FASTA: opt: 1311 Z-score: 1457.7 E(): 2.7e-73 Smith-Waterman score: 1688; 47.478identity in 575 aa overlap Schu S4 seems to have extra sequence in between 340-420 aa; cytochrome d terminal oxidase, polypeptide subunit I	complement(291761..293539)	Francisella tularensis subsp. tularensis FSC198	4200282
YP_666462.1	CDS	yajR	NC_008245.1	293968	295335	R	Similar to AAO89830 (Q83EP3) Major facilitator family transporter from Coxiella burnetii (458 aa). FASTA: opt: 1379 Z-score: 1410.6 E(): 1.1e-70 Smith-Waterman score: 1379; 46.102 identity in 449 aa overlap; major facilitator transporter	complement(293968..295335)	Francisella tularensis subsp. tularensis FSC198	4200700
YP_666463.1	CDS	cyoA	NC_008245.1	295696	296598	D	Similar to Q87DQ7 Cytochrome O ubiquinol oxidase subunit II from Xylella fastidiosa (319 aa). FASTA: opt: 956 Z-score: 1145.6 E(): 6.4e-56 Smith-Waterman score: 956; 49.477 identity in 287 aa overlap; cytochrome O ubiquinol oxidase subunit II	295696..296598	Francisella tularensis subsp. tularensis FSC198	4199516
YP_666464.1	CDS	cyoB	NC_008245.1	296637	298667	D	Similar to AAO70008 (Q8XG02) Cytochrome o ubiquinol oxidase subunit I from Salmonella typhi (663 aa). FASTA: opt: 3045 Z-score: 3221.2 E(): 1.6e-171 Smith-Waterman score: 3045; 64.361identity in 665 aa overlap; cytochrome O ubiquinol oxidase subunit I	296637..298667	Francisella tularensis subsp. tularensis FSC198	4199517
YP_666465.1	CDS	cyoC	NC_008245.1	298664	299266	D	Similar to Q87IH7 Cytochrome o ubiquinol oxidase,subunit III from Vibrio parahaemolyticus (200 aa). FASTA: opt: 768 Z-score: 931.9 E(): 5.1e-44 Smith-Waterman score: 768; 55.276identity in 199 aa overlap; cytochrome O ubiquinol oxidase, subunit III	298664..299266	Francisella tularensis subsp. tularensis FSC198	4199518
YP_666466.1	CDS	cyoD	NC_008245.1	299268	299600	D	Similar to Q8ZC55 Cytochrome O ubiquinol oxidase subunit IV from Yersinia pestis (110 aa). FASTA: opt: 325 Z-score: 419.7 E(): 1.7e-15 Smith-Waterman score: 325; 50.505 identity in 99 aa overlap; cytochrome O ubiquinol oxidase subunit IV	299268..299600	Francisella tularensis subsp. tularensis FSC198	4199519
YP_666467.1	CDS	cyoE	NC_008245.1	299631	300479	D	converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase	299631..300479	Francisella tularensis subsp. tularensis FSC198	4199520
YP_666468.1	CDS	lpxD2	NC_008245.1	300624	301667	R	Similar to Q8A014 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase from Bacteroides thetaiotaomicron (346 aa). FASTA: opt: 687 Z-score: 795.8 E(): 2e-36 Smith-Waterman score: 687; 33.431 identity in 341 aa overlap paralog of FTF1571; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	complement(300624..301667)	Francisella tularensis subsp. tularensis FSC198	4199648
YP_666469.1	CDS	FTF0287c	NC_008245.1	301735	302430	R	Similar to Q8XIW2 Hypothetical protein CPE2001 from Clostridium perfringens (229 aa). FASTA: opt: 806 Z-score: 994.2 E(): 1.7e-47 Smith-Waterman score: 806; 51.948 identity in 231 aa overlap ORF ftt0287c; hypothetical protein	complement(301735..302430)	Francisella tularensis subsp. tularensis FSC198	4200415
YP_666470.1	CDS	pdxY	NC_008245.1	302430	303281	R	Similar to Q8D4Q2 Pyridoxal/pyridoxine/pyridoxamine kinase from Vibrio vulnificus (290 aa). FASTA: opt: 611 Z-score: 766.0 E(): 8.9e-35 Smith-Waterman score: 611; 38.545identity in 275 aa overlap; pyridoxal kinase	complement(302430..303281)	Francisella tularensis subsp. tularensis FSC198	4199238
YP_666471.1	CDS	FTF0289c	NC_008245.1	303288	303722	R	ORF ftt0289c; hypothetical protein	complement(303288..303722)	Francisella tularensis subsp. tularensis FSC198	4200416
YP_666472.1	CDS	moxR	NC_008245.1	303868	304824	D	Similar to Q87YN6 MoxR protein, putative, from Pseudomonas syringae (319 aa). FASTA: opt: 1309 Z-score: 1518.5 E(): 9.9e-77 Smith-Waterman score: 1309; 61.489 identity in 309 aa overlap; methanol dehydrogenase regulatory protein	303868..304824	Francisella tularensis subsp. tularensis FSC198	4199850
YP_666473.1	CDS	FTF0291	NC_008245.1	304837	305748	D	Similar to Q87YN5 Conserved hypothetical protein from Pseudomonas syringae (314 aa). FASTA: opt: 561 Z-score: 693.3 bits: 136.4 E(): 1e-30 Smith-Waterman score: 561; 30.479 identity in 292 aa overlap ORF ftt0291; hypothetical protein	304837..305748	Francisella tularensis subsp. tularensis FSC198	4200417
YP_666474.1	CDS	FTF0292	NC_008245.1	305738	306214	D	Similar to Q8D3W9 Conserved hypothetical protein from Vibrio vulnificus (156 aa). FASTA: opt: 228 Z-score: 276.8 E(): 1.5e-07 Smith-Waterman score: 228; 28.481 identity in 158 aa overlap ORF ftt0292; hypothetical protein	305738..306214	Francisella tularensis subsp. tularensis FSC198	4200418
YP_666475.1	CDS	FTF0293	NC_008245.1	306193	307212	D	Similar to Q88LA6 Von Willebrand factor type A domain protein from Pseuodmonas putida (358 aa). FASTA: opt: 905 Z-score: 1015.4 E(): 1.1e-48 Smith-Waterman score: 905; 45.122 identity in 328 aa overlap ORF ftt0293; hypothetical protein	306193..307212	Francisella tularensis subsp. tularensis FSC198	4200419
YP_666476.1	CDS	FTF0295	NC_008245.1	308945	310570	D	Similar to Q8ECP0 Conserved hypothetical protein from Shewanella oneidensis (555 aa). FASTA: opt: 529 Z-score: 628.4 E(): 4.1e-27 Smith-Waterman score: 529; 24.371 identity in 517 aa overlap ORF ftt0295; hypothetical protein	308945..310570	Francisella tularensis subsp. tularensis FSC198	4200421
YP_666477.1	CDS	pcp	NC_008245.1	310571	311248	D	Similar to PCP_CLOPE (Q8XKH1) Pyrrolidone-carboxylate peptidase from Clostridium perfringens (215 aa). FASTA: opt: 710 Z-score: 844.3 E(): 3.9e-39 Smith-Waterman score: 710; 52.020identity in 198 aa overlap; pyrrolidone-carboxylate peptidase	310571..311248	Francisella tularensis subsp. tularensis FSC198	4199228
YP_666478.1	CDS	FTF0297	NC_008245.1	311256	311738	D	ORF ftt0297; putative cytochrome c-type biogenesis protein	311256..311738	Francisella tularensis subsp. tularensis FSC198	4200422
YP_666479.1	CDS	holC	NC_008245.1	311769	312209	D	Similar to Q8XWQ9 Probable DNA polymerase III (CHI subunit) protein from Ralstonia solanacearum (142 aa). FASTA: opt: 142 Z-score: 187.9 E(): 0.013 Smith-Waterman score: 142; 30.000identity in 120 aa overlap; DNA polymerase III subunit chi	311769..312209	Francisella tularensis subsp. tularensis FSC198	4200199
YP_666480.1	CDS	valS	NC_008245.1	312341	315100	D	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase	312341..315100	Francisella tularensis subsp. tularensis FSC198	4200138
YP_666481.1	CDS	FTF0300	NC_008245.1	315129	315983	D	ORF ftt0300; hypothetical protein	315129..315983	Francisella tularensis subsp. tularensis FSC198	4200423
YP_666482.1	CDS	FTF0301	NC_008245.1	316056	316925	D	ORF ftt0301; hypothetical protein	316056..316925	Francisella tularensis subsp. tularensis FSC198	4200424
YP_666483.1	CDS	FTF0302	NC_008245.1	317109	317444	D	ORF ftt0302; hypothetical protein	317109..317444	Francisella tularensis subsp. tularensis FSC198	4200425
YP_666484.1	CDS	lldD1	NC_008245.1	317441	318598	R	Similar to Q9JTX1 L-lactate dehydrogenase from Neisseria meningitidis (390 aa). FASTA: opt: 1591 Z-score: 1977.5 E(): 3e-102 Smith-Waterman score: 1591; 60.789 identity in 380 aa overlap; L-lactate dehydrogenase	complement(317441..318598)	Francisella tularensis subsp. tularensis FSC198	4199556
YP_666485.1	CDS	nfnB	NC_008245.1	318625	319278	R	catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase	complement(318625..319278)	Francisella tularensis subsp. tularensis FSC198	4200239
YP_666486.1	CDS	FTF0305	NC_008245.1	319418	319795	D	Similar to Q88NZ1 MutT/nudix family protein from Pseuodomonas putida (137 aa). FASTA: opt: 224 Z-score: 293.2 E(): 1.8e-08 Smith-Waterman score: 224; 34.545 identity in 110 aa overlap ORF ftt0305; MutT/nudix family protein	319418..319795	Francisella tularensis subsp. tularensis FSC198	4200426
YP_666487.1	CDS	fumC	NC_008245.1	319968	321359	D	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase	319968..321359	Francisella tularensis subsp. tularensis FSC198	4199201
YP_666488.1	CDS	gltX	NC_008245.1	321489	322895	D	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase	321489..322895	Francisella tularensis subsp. tularensis FSC198	4199800
YP_666489.1	CDS	FTF0308	NC_008245.1	322886	323863	D	ORF ftt0308; hypothetical protein	322886..323863	Francisella tularensis subsp. tularensis FSC198	4200427
YP_666490.1	CDS	isftu2	NC_008245.1	323887	324630	R	ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa).; transposase	complement(323887..324630)	Francisella tularensis subsp. tularensis FSC198	4200191
YP_666491.1	CDS	FTF0310	NC_008245.1	324926	326380	D	Similar to Q8XT33 Probable amino-acid permease transmembrane protein from Ralstonia solanacearum (543 aa). FASTA: opt: 999 Z-score: 1146.0 E(): 5.5e-5 Smith-Waterman score: 999; 34.924 identity in 461 aa overlap ORF ftt0310; amino acid permease	324926..326380	Francisella tularensis subsp. tularensis FSC198	4200428
YP_666492.1	CDS	FTF0311c	NC_008245.1	326712	327635	R	Similar to Q9KKV6 Hypothetical protein VCA0994 from Vibrio cholerae (326 aa). FASTA: opt: 558 Z-score: 686.8 E(): 2.3e-30 Smith-Waterman score: 558; 31.949 identity in 313 aa overlap ORF ftt0311c; hypothetical protein	complement(326712..327635)	Francisella tularensis subsp. tularensis FSC198	4200429
YP_666493.1	CDS	folA	NC_008245.1	327717	328217	R	Similar to Q9K7B6 Dihydrofolate reductase from Bacillus halodurans (163 aa). FASTA: opt: 465 Z-score: 598.3 E(): 2e-25 Smith-Waterman score: 465; 41.566 identity in 166 aa overlap; dihydrofolate reductase type I	complement(327717..328217)	Francisella tularensis subsp. tularensis FSC198	4199413
YP_666494.1	CDS	rpsB	NC_008245.1	328449	329168	D	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2	328449..329168	Francisella tularensis subsp. tularensis FSC198	4200334
YP_666495.1	CDS	tsf	NC_008245.1	329190	330059	D	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts	329190..330059	Francisella tularensis subsp. tularensis FSC198	4198972
YP_666496.1	CDS	pyrH	NC_008245.1	330063	330812	D	Catalyzes the phosphorylation of UMP to UDP; uridylate kinase	330063..330812	Francisella tularensis subsp. tularensis FSC198	4200592
YP_666497.1	CDS	frr	NC_008245.1	330841	331398	D	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor	330841..331398	Francisella tularensis subsp. tularensis FSC198	4199190
YP_666498.1	CDS	uppS	NC_008245.1	331431	332204	D	catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase	331431..332204	Francisella tularensis subsp. tularensis FSC198	4198985
YP_666499.1	CDS	cdsA	NC_008245.1	332218	333012	D	Similar to Q88MH5 Phosphatidate cytidylyltransferase from Pseudomonas putida (271 aa). FASTA: 398 opt: 534 Z-score: 626.6 E(): 5.2e-27 Smith-Waterman score: 536; 35.926 identity in 270 aa overlap; phosphatidate cytidylyltransferase	332218..333012	Francisella tularensis subsp. tularensis FSC198	4200320
YP_666500.1	CDS	dut	NC_008245.1	333022	333468	D	catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase	333022..333468	Francisella tularensis subsp. tularensis FSC198	4199666
YP_666501.1	CDS	pgsA	NC_008245.1	333472	334068	D	Similar to Q8XFD0 Phosphotidylglycerophosphate synthetase from Salmonella typhi (182 aa). FASTA: opt: 575 Z-score: 728.4 E(): 1.1e-32 Smith-Waterman score: 618; 50.000identity in 188 aa overlap; phosphatidylglycerophosphate synthetase	333472..334068	Francisella tularensis subsp. tularensis FSC198	4199245
YP_666502.1	CDS	rpsL	NC_008245.1	334203	334577	D	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12	334203..334577	Francisella tularensis subsp. tularensis FSC198	4198950
YP_666503.1	CDS	rpsG	NC_008245.1	334616	335089	D	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7	334616..335089	Francisella tularensis subsp. tularensis FSC198	4200339
YP_666504.1	CDS	fusA	NC_008245.1	335104	337218	D	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G	335104..337218	Francisella tularensis subsp. tularensis FSC198	4199203
YP_666505.1	CDS	rpsJ	NC_008245.1	337239	337556	D	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10	337239..337556	Francisella tularensis subsp. tularensis FSC198	4200342
YP_666506.1	CDS	rplC	NC_008245.1	337660	338295	D	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3	337660..338295	Francisella tularensis subsp. tularensis FSC198	4200775
YP_666507.1	CDS	rplD	NC_008245.1	338325	338948	D	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4	338325..338948	Francisella tularensis subsp. tularensis FSC198	4200776
YP_666508.1	CDS	rplW	NC_008245.1	338945	339244	D	binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23	338945..339244	Francisella tularensis subsp. tularensis FSC198	4198999
YP_666509.1	CDS	rplB	NC_008245.1	339266	340090	D	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2	339266..340090	Francisella tularensis subsp. tularensis FSC198	4200774
YP_666510.1	CDS	rpsS	NC_008245.1	340105	340383	D	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19	340105..340383	Francisella tularensis subsp. tularensis FSC198	4198957
YP_666511.1	CDS	rplV	NC_008245.1	340399	340734	D	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22	340399..340734	Francisella tularensis subsp. tularensis FSC198	4198998
YP_666512.2	CDS	rpsC	NC_008245.1	340749	>341408	D	truncated; forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3	340749..>341408	Francisella tularensis subsp. tularensis FSC198	4200335
YP_666513.1	CDS	rplP	NC_008245.1	341421	341834	D	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16	341421..341834	Francisella tularensis subsp. tularensis FSC198	4198992
YP_666514.1	CDS	rpmC	NC_008245.1	341834	342034	D	one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29	341834..342034	Francisella tularensis subsp. tularensis FSC198	4199004
YP_666515.1	CDS	rpsQ	NC_008245.1	342047	342298	D	primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17	342047..342298	Francisella tularensis subsp. tularensis FSC198	4198955
YP_666516.1	CDS	rplN	NC_008245.1	342390	342758	D	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14	342390..342758	Francisella tularensis subsp. tularensis FSC198	4198990
YP_666517.1	CDS	rplX	NC_008245.1	342780	343097	D	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24	342780..343097	Francisella tularensis subsp. tularensis FSC198	4199000
YP_666518.1	CDS	rplE	NC_008245.1	343109	343648	D	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5	343109..343648	Francisella tularensis subsp. tularensis FSC198	4200777
YP_666519.1	CDS	rpsN	NC_008245.1	343667	343972	D	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14	343667..343972	Francisella tularensis subsp. tularensis FSC198	4198952
YP_666520.1	CDS	rpsH	NC_008245.1	343989	344387	D	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8	343989..344387	Francisella tularensis subsp. tularensis FSC198	4200340
YP_666521.1	CDS	rplF	NC_008245.1	344406	344942	D	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6	344406..344942	Francisella tularensis subsp. tularensis FSC198	4200778
YP_666522.1	CDS	rplR	NC_008245.1	344965	345318	D	binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18	344965..345318	Francisella tularensis subsp. tularensis FSC198	4198994
YP_666523.1	CDS	rpsE	NC_008245.1	345346	345846	D	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5	345346..345846	Francisella tularensis subsp. tularensis FSC198	4200337
YP_666524.1	CDS	rpmD	NC_008245.1	345853	346038	D	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30	345853..346038	Francisella tularensis subsp. tularensis FSC198	4199005
YP_666525.1	CDS	rplO	NC_008245.1	346045	346476	D	late assembly protein; 50S ribosomal protein L15	346045..346476	Francisella tularensis subsp. tularensis FSC198	4198991
YP_666526.1	CDS	secY	NC_008245.1	346487	347812	D	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY	346487..347812	Francisella tularensis subsp. tularensis FSC198	4200740
YP_666527.1	CDS	rpmJ	NC_008245.1	347836	347949	D	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36	347836..347949	Francisella tularensis subsp. tularensis FSC198	4200325
YP_666528.1	CDS	rpsM	NC_008245.1	348066	348422	D	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13	348066..348422	Francisella tularensis subsp. tularensis FSC198	4198951
YP_666529.1	CDS	rpsK	NC_008245.1	348462	348851	D	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11	348462..348851	Francisella tularensis subsp. tularensis FSC198	4198949
YP_666530.1	CDS	rpsD	NC_008245.1	348873	349493	D	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4	348873..349493	Francisella tularensis subsp. tularensis FSC198	4200336
YP_666531.1	CDS	rpoA1	NC_008245.1	349551	350522	D	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha	349551..350522	Francisella tularensis subsp. tularensis FSC198	4200326
YP_666532.1	CDS	rplQ	NC_008245.1	350567	351004	D	is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17	350567..351004	Francisella tularensis subsp. tularensis FSC198	4198993
YP_666533.1	CDS	isftu1	NC_008245.1	351158	351942	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(351158..351484,351484..351942)	Francisella tularensis subsp. tularensis FSC198	4199624
YP_666534.1	CDS	FTF0354	NC_008245.1	352871	353866	D	Duplicate of FTF0378 and FTF1263 ORF ftt0354; hypothetical protein	352871..353866	Francisella tularensis subsp. tularensis FSC198	4200430
YP_666535.1	CDS	isftu1	NC_008245.1	354158	354942	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(354158..354616,354616..354942))	Francisella tularensis subsp. tularensis FSC198	4199625
YP_666536.1	CDS	htpG	NC_008245.1	355104	356990	D	molecular chaperone; heat shock protein 90	355104..356990	Francisella tularensis subsp. tularensis FSC198	4200210
YP_666537.1	CDS	isftu1	NC_008245.1	357314	358098	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(357314..357772,357772..358098))	Francisella tularensis subsp. tularensis FSC198	4199626
YP_666538.1	CDS	FTF0359	NC_008245.1	359366	359836	D	ORF ftt0359; hypothetical protein	359366..359836	Francisella tularensis subsp. tularensis FSC198	4200432
YP_666539.1	CDS	FTF0360	NC_008245.1	359973	360797	D	Similar to Q82V84 Short-chain dehydrogenase/reductase (SDR) superfamily from Nitrosomonas europaea (279 aa). FASTA: opt: 829 Z-score: 982.8 E(): 7.5e-47 Smith-Waterman score: 829; 49.632 identity in 272 aa overlap ORF ftt0360; short-chain dehydrogenase	359973..360797	Francisella tularensis subsp. tularensis FSC198	4200433
YP_666540.1	CDS	FTF0361c	NC_008245.1	360819	362168	R	Similar to Q8Z506 Putative amino acid transporter from Salmonella typhi (473 aa). FASTA: opt: 717 Z-score: 754.8 E(): 3.8e-34 Smith-Waterman score: 755; 29.783 identity in 460 aa overlap ORF ftt0361c; amino acid transporter	complement(360819..362168)	Francisella tularensis subsp. tularensis FSC198	4200434
YP_666541.1	CDS	FTF0362c	NC_008245.1	362427	363299	R	ORF ftt0362c; hypothetical protein	complement(362427..363299)	Francisella tularensis subsp. tularensis FSC198	4200435
YP_666542.1	CDS	isftu1	NC_008245.1	363467	364251	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(363467..363793,363793..364251)	Francisella tularensis subsp. tularensis FSC198	4199627
YP_666543.1	CDS	FTF0364c	NC_008245.1	364375	364824	R	ORF ftt0364c; hypothetical protein	complement(364375..364824)	Francisella tularensis subsp. tularensis FSC198	4200436
YP_666544.1	CDS	poxF	NC_008245.1	365305	366036	D	Similar to Q8PFB8 Phenol hydroxylase from Xanthomonas axonopodis (365 aa). FASTA: opt: 567 Z-score: 717.5 E(): 4.5e-32 Smith-Waterman score: 567; 38.211 identity in 246 aa overlap The protein seems to be shorter (<115 aa) than the matching proteins.; phenol hydroxylase	365305..366036	Francisella tularensis subsp. tularensis FSC198	4199742
YP_666545.1	CDS	rpmE	NC_008245.1	366158	366373	D	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31	366158..366373	Francisella tularensis subsp. tularensis FSC198	4199006
YP_666546.1	CDS	gshA	NC_008245.1	366584	368089	R	Similar to Q88AR1 Glutamate--cysteine ligase from Pseudomonas syringae (529 aa). FASTA: opt: 1113 Z-score: 1281.1 E(): 1.8e-63 Smith-Waterman score: 1113; 39.250 identity in 507 aa overlap; glutamate--cysteine ligase	complement(366584..368089)	Francisella tularensis subsp. tularensis FSC198	4200304
YP_666547.1	CDS	mviN	NC_008245.1	368142	369686	R	Similar to AAO89943 (Q83ED5) Integral membrane protein MviN from Coxiella burnetii (515 aa). FASTA: opt: 836 Z-score: 887.1 E(): 1.6e-41 Smith-Waterman score: 836; 30.452 identity in 509 aa overlap; virulence factor MviN	complement(368142..369686)	Francisella tularensis subsp. tularensis FSC198	4200116
YP_666548.1	CDS	FTF0369c	NC_008245.1	369709	370770	R	ORF ftt0369c; hypothetical protein	complement(369709..370770)	Francisella tularensis subsp. tularensis FSC198	4200437
YP_666549.1	CDS	yjeE	NC_008245.1	370853	371263	R	Similar to Q8Z189 Hypothetical protein yjeE from Salmonella typhi (153 aa). FASTA: opt: 517 Z-score: 623.3 E(): 7.9e-27 Smith-Waterman score: 517; 56.489 identity in 131 aa overlap; nucleotide-binding protein, yjeE	complement(370853..371263)	Francisella tularensis subsp. tularensis FSC198	4199112
YP_666550.1	CDS	folC	NC_008245.1	371241	372422	R	Similar to Q8ECR5 FolC bifunctional protein from Shewanella oneidensis (431 aa). FASTA: opt: 507 Z-score: 630.2 E(): 3.3e-27 Smith-Waterman score: 627; 32.274 identity in 409 aa overlap; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase	complement(371241..372422)	Francisella tularensis subsp. tularensis FSC198	4199415
YP_666551.1	CDS	accD	NC_008245.1	372437	373345	R	Similar to Q8XFJ5 Acetyl-CoA carboxylase beta subunit from Salmonella typhi (304 aa). FASTA: opt: 1197 Z-score: 1430.2 E(): 9.1e-72 Smith-Waterman score: 1197; 62.116 identity in 293 aa overlap; Acetyl-CoA carboxylase beta subunit	complement(372437..373345)	Francisella tularensis subsp. tularensis FSC198	4199749
YP_666552.1	CDS	ndk	NC_008245.1	373381	373803	R	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase	complement(373381..373803)	Francisella tularensis subsp. tularensis FSC198	4200238
YP_666553.1	CDS	pyrG	NC_008245.1	373876	375516	R	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase	complement(373876..375516)	Francisella tularensis subsp. tularensis FSC198	4200591
YP_666554.1	CDS	FTF0376c	NC_008245.1	377434	378492	R	Weak hits at position aa 250-350 to many cytochrome oxidase subunit I eg:(Q85L50). ORF ftt0376c; hypothetical protein	complement(377434..378492)	Francisella tularensis subsp. tularensis FSC198	4200439
YP_666555.1	CDS	isftu1	NC_008245.1	378859	379643	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(378859..379188,379188..379643)	Francisella tularensis subsp. tularensis FSC198	4199628
YP_666556.1	CDS	FTF0378c	NC_008245.1	379935	380930	R	Duplicate of FTF0354 and FTF1263 ORF ftt0378c; hypothetical protein	complement(379935..380930)	Francisella tularensis subsp. tularensis FSC198	4200440
YP_666557.1	CDS	gdh	NC_008245.1	381967	383316	R	converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase	complement(381967..383316)	Francisella tularensis subsp. tularensis FSC198	4199282
YP_666558.1	CDS	isftu2	NC_008245.1	383655	384398	D	ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa).; transposase	383655..384398	Francisella tularensis subsp. tularensis FSC198	4199287
YP_666559.1	CDS	FTF0382	NC_008245.1	384523	384627	D	ORF ftt0382; hypothetical protein	384523..384627	Francisella tularensis subsp. tularensis FSC198	4200441
YP_666560.1	CDS	FTF0383	NC_008245.1	385638	385973	D	ORF ftt0383; hypothetical protein	385638..385973	Francisella tularensis subsp. tularensis FSC198	4200442
YP_666561.1	CDS	psd	NC_008245.1	385946	386797	R	catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase	complement(385946..386797)	Francisella tularensis subsp. tularensis FSC198	4199946
YP_666562.1	CDS	FTF0385	NC_008245.1	386897	387877	D	ORF ftt0385; hypothetical protein	386897..387877	Francisella tularensis subsp. tularensis FSC198	4200443
YP_666563.1	CDS	nadM	NC_008245.1	387886	388929	D	NadM-Nudix subfamily; involved in creation of nicotanimide adenine dinucleotide NAD from either biosynthetic or salvage pathways; bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase	387886..388929	Francisella tularensis subsp. tularensis FSC198	4200233
YP_666564.1	CDS	glmU	NC_008245.1	388943	390310	D	Similar to Q9KNH7 UDP-N-acetylglucosamine pyrophosphorylase from Vibrio cholerae (453 aa). FASTA: opt: 1597 Z-score: 1863.6 E(): 6.5e-96 Smith-Waterman score: 1597; 53.201 identity in 453 aa overlap; UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	388943..390310	Francisella tularensis subsp. tularensis FSC198	4199788
YP_666565.1	CDS	glmS	NC_008245.1	390331	392169	D	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase	390331..392169	Francisella tularensis subsp. tularensis FSC198	4199787
YP_666566.1	CDS	FTF0389	NC_008245.1	392253	392777	D	Similar to Q9RWR2 Acetyltransferase, putative, from Deinococcus radiodurans (188 aa). FASTA: opt: 188 Z-score: 245.7 E(): 8.5e-06 Smith-Waterman score: 188; 28.105 identity in 153 aa overlap ORF ftt0389; acetyltransferase	392253..392777	Francisella tularensis subsp. tularensis FSC198	4200444
YP_666567.1	CDS	rpsU	NC_008245.1	392770	392967	R	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21	complement(392770..392967)	Francisella tularensis subsp. tularensis FSC198	4198959
YP_666568.1	CDS	cspC	NC_008245.1	392967	393170	R	Similar to Q8D6M5 Cold shock protein from Vibrio vulnificus (70 aa). FASTA: opt: 272 Z-score: 403.6 E(): 1.4e-14 Smith-Waterman score: 272; 58.571 identity in 70 aa overlap; cold shock protein	complement(392967..393170)	Francisella tularensis subsp. tularensis FSC198	4200280
YP_666569.1	CDS	FTF0392c	NC_008245.1	393418	393747	R	Similar to Q8TT97 Hypothetical protein MA0540 from Methanosarcina mazei (95 aa). FASTA: opt: 151 Z-score: 197.5 E(): 0.0038 Smith-Waterman score: 151; 35.789 identity in 95 aa overlap ORF ftt0392c; hypothetical protein	complement(393418..393747)	Francisella tularensis subsp. tularensis FSC198	4200445
YP_666570.1	CDS	map	NC_008245.1	393874	394644	D	Similar to Q886P4 Methionine aminopeptidase,type I from Pseudomonas syringae (260 aa). FASTA: opt: 1243 Z-score: 1568.2 E(): 1.9e-79 Smith-Waterman score: 1243; 70.120 identity in 251 aa overlap; methionine aminopeptidase	393874..394644	Francisella tularensis subsp. tularensis FSC198	4199661
YP_666571.1	CDS	FTF0394	NC_008245.1	394646	395494	D	ORF ftt0394; hypothetical protein	394646..395494	Francisella tularensis subsp. tularensis FSC198	4200446
YP_666572.1	CDS	FTF0395	NC_008245.1	395540	396253	D	Similar to Q9L5J1 hypothetical protein from Salmonella typhi (259 aa). FASTA: opt: 585 Z-score: 707.5 E(): 1.6e-31 Smith-Waterman score: 680; 46.743 identity in 261 aa overlap ORF ftt0395; hypothetical protein	395540..396253	Francisella tularensis subsp. tularensis FSC198	4200447
YP_666573.1	CDS	parC	NC_008245.1	396386	398611	D	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A	396386..398611	Francisella tularensis subsp. tularensis FSC198	4200095
YP_666574.1	CDS	mtn	NC_008245.1	398611	399297	D	enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	398611..399297	Francisella tularensis subsp. tularensis FSC198	4200103
YP_666575.1	CDS	FTF0398c	NC_008245.1	399284	399883	R	ORF ftt0398c; hypothetical protein	complement(399284..399883)	Francisella tularensis subsp. tularensis FSC198	4200448
YP_666576.1	CDS	FTF0399c	NC_008245.1	399876	400994	R	Similar to Q885D8 BNR/Asp-box repeat protein from Pseudomonas syringae (432 aa). FASTA: opt: 536 Z-score: 654.4 E(): 1.5e-28 Smith-Waterman score: 536; 31.922 identity in 307 aa overlap ORF ftt0399c; BNR/Asp-box repeat-containing protein	complement(399876..400994)	Francisella tularensis subsp. tularensis FSC198	4200449
YP_666577.1	CDS	slt	NC_008245.1	401193	403169	D	Similar to Q88L07 Soluble lytic transglycosylase,putative from Pseudomonas putida (657 aa). FASTA: opt: 596 Z-score: 646.0 E(): 3.9e-28 Smith-Waterman score: 819; 27.822 identity in 629 aa overlap.; soluble lytic murein transglycosylase	401193..403169	Francisella tularensis subsp. tularensis FSC198	4200744
YP_666578.1	CDS	FTF0401	NC_008245.1	403459	404181	D	Partial homology to carboxy terminus of Q9CLV4a Hypothetical protein PM1097 from Pasteurella multocida (417 aa). FASTA: opt: 269 Z-score: 330.3 E(): 1.7e-10 Smith-Waterman score: 269; 26.050identity in 238 aa overlap ORF ftt0401; hypothetical protein	403459..404181	Francisella tularensis subsp. tularensis FSC198	4200450
YP_666579.1	CDS	dnaE	NC_008245.1	404538	408017	D	Similar to DP3A_SALTY (P14567) DNA polymerase III alpha subunit from Salmonella typhimurium (1160 aa). FASTA: opt: 3099 Z-score: 3288.3 E(): 2.6e-175 Smith-Waterman score: 3099; 44.781identity in 1121 aa overlap.; DNA polymerase III subunit alpha	404538..408017	Francisella tularensis subsp. tularensis FSC198	4199352
YP_666580.1	CDS	def1	NC_008245.1	408093	408728	D	Similar to DEF_LEPIN (Q93LE9) Peptide deformylase from Leptospira interrogans (178 aa). FASTA: opt: 312 Z-score: 399.2 E(): 2.4e-14 Smith-Waterman score: 312; 35.758 identity in 165 aa overlap; peptide deformylase	408093..408728	Francisella tularensis subsp. tularensis FSC198	4199534
YP_666581.1	CDS	lolC	NC_008245.1	409432	410694	D	Similar to Q83CV1 Putative lipoprotein ABC transporter,permease protein from Coxiella burnetii (414 aa). FASTA: opt: 1273 Z-score: 1436.4 E(): 4.1e-72 Smith-Waterman score: 1273; 48.104 identity in 422 aa overlap; lipoprotein releasing system, subunit C,putative membrane protein	409432..410694	Francisella tularensis subsp. tularensis FSC198	4199560
YP_666582.1	CDS	lolD	NC_008245.1	410687	411382	D	Similar to LOLD_NEIMA (P57030) Lipoprotein releasing system ATP-binding transport protein from Neisseria meningitidis (231 aa). FASTA: opt: 791 Z-score: 892.8 E(): 7e-42 Smith-Waterman score: 791; 51.770 identity in 226 aa overlap; lipoprotein releasing system, subunit D, ABC transporter ATP-binding protein	410687..411382	Francisella tularensis subsp. tularensis FSC198	4199561
YP_666583.1	CDS	cadA	NC_008245.1	411499	413640	D	Similar to DCLY_ECOLI (P23892) Lysine decarboxylase, inducible from E. coli (715 aa) FASTA: opt: 2608 Z-score: 3095.0 E(): 1.7e-164 Smith-Waterman score: 2608; 53.912 identity in 703 aa overlap; lysine decarboxylase, inducable	411499..413640	Francisella tularensis subsp. tularensis FSC198	4200312
YP_666584.1	CDS	gcvT	NC_008245.1	413732	414808	D	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T	413732..414808	Francisella tularensis subsp. tularensis FSC198	4199281
YP_666585.1	CDS	gcvH1	NC_008245.1	414864	415247	D	Similar to Q8FE66 Glycine cleavage system H protein from E coli (130 aa). FASTA: opt: 526 Z-score: 699.9 E(): 4.3e-31 Smith-Waterman score: 526; 60.938 identity in 128 aa overlap; glycine cleavage system H protein	414864..415247	Francisella tularensis subsp. tularensis FSC198	4199277
YP_666586.1	CDS	gcvP1	NC_008245.1	415311	416678	D	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1	415311..416678	Francisella tularensis subsp. tularensis FSC198	4199279
YP_666587.1	CDS	gcvP2	NC_008245.1	416684	418129	D	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2	416684..418129	Francisella tularensis subsp. tularensis FSC198	4199280
YP_666588.1	CDS	aroE2	NC_008245.1	418249	419094	R	Similar to Q8FQC7 Putative shikimate 5-dehydrogenase from Corynebacterium efficiens(269 aa). FASTA: opt: 283 Z-score: 321.7 E(): 4.6e-10 Smith-Waterman score: 287; 28.077 identity in 260 aa overlap.; shikimate 5-dehydrogenase	complement(418249..419094)	Francisella tularensis subsp. tularensis FSC198	4199436
YP_666589.1	CDS	pulB	NC_008245.1	419120	422332	R	Similar to Q8XK16 Pullulanase from Clostridium perfringens (1064 aa). FASTA: opt: 3419 Z-score: 3958.4 E(): 1.4e-212 Smith-Waterman score: 3419; 48.369identity in 1042 aa overlap Other FASTA hits have lower scores due to generally being smaller in size. Q8XK16 is an electronic annotation; pullulonase	complement(419120..422332)	Francisella tularensis subsp. tularensis FSC198	4199950
YP_666590.1	CDS	glgB	NC_008245.1	422366	424288	R	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein	complement(422366..424288)	Francisella tularensis subsp. tularensis FSC198	4199783
YP_666591.1	CDS	pgm	NC_008245.1	424590	426224	D	catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase	424590..426224	Francisella tularensis subsp. tularensis FSC198	4199244
YP_666592.1	CDS	glgA	NC_008245.1	427540	429009	D	catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase	427540..429009	Francisella tularensis subsp. tularensis FSC198	4199782
YP_666593.1	CDS	malP	NC_008245.1	429114	431387	D	Similar to Q8DN49 Maltodextrin phosphorylase from Streptococcus pneumoniae (752 aa). FASTA: opt: 2938 Z-score: 3443.0 E(): 6.9e-184 Smith-Waterman score: 2938; 59.569 identity in 742 aa overlap; maltodextrin phosphorylase	429114..431387	Francisella tularensis subsp. tularensis FSC198	4199658
YP_666594.1	CDS	malA	NC_008245.1	431431	432894	D	amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase	431431..432894	Francisella tularensis subsp. tularensis FSC198	4199657
YP_666595.1	CDS	glyQ	NC_008245.1	432968	433876	D	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha	432968..433876	Francisella tularensis subsp. tularensis FSC198	4200289
YP_666596.1	CDS	murE	NC_008245.1	434087	435526	D	Similar to MURE_NEIMB (Q9K0Y9) UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase from Neisseria meningitidis (492 aa). FASTA: opt: 1037 Z-score: 1223.7, E(): 2.9e-60 Smith-Waterman score: 1037; 40.795 identity in 478 aa overlap; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase	434087..435526	Francisella tularensis subsp. tularensis FSC198	4200108
YP_666597.1	CDS	murF	NC_008245.1	436318	437676	D	Similar to Q87SG8 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate -D-alanyl-D-alanyl ligase from Vibrio parahaemolyticus (454 aa). FASTA: opt: 870 Z-score: 1005.8 E(): 3.9e-48 Smith-Waterman score: 870; 35.011 identity in 457 aa overlap deleted EC_number 6.3.2.15; UDP-N--acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase	436318..437676	Francisella tularensis subsp. tularensis FSC198	4200109
YP_666598.1	CDS	FTF0423	NC_008245.1	437685	437864	D	ORF ftt0423; hypothetical protein	437685..437864	Francisella tularensis subsp. tularensis FSC198	4200452
YP_666599.1	CDS	FTF0424	NC_008245.1	437995	438504	D	ORF ftt0424; hypothetical protein	437995..438504	Francisella tularensis subsp. tularensis FSC198	4200453
YP_666600.1	CDS	asd	NC_008245.1	438560	439654	R	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase	complement(438560..439654)	Francisella tularensis subsp. tularensis FSC198	4199688
YP_666601.1	CDS	thrC1	NC_008245.1	442964	444250	D	catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase	442964..444250	Francisella tularensis subsp. tularensis FSC198	4199141
YP_666602.1	CDS	speH	NC_008245.1	444891	445325	D	Similar to SPEH_METJA (Q57763) S-adenosylmethionine decarboxylase proenzyme from Methanococcus jannaschii (124 aa). FASTA: opt: 355 Z-score: 487.2, E(): 3e-19 Smith-Waterman score: 355; 44.737 identity in 114 aa overlap; S-adenosylmethionine decarboxylase	444891..445325	Francisella tularensis subsp. tularensis FSC198	4199082
YP_666603.1	CDS	speE	NC_008245.1	445325	446194	D	catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase	445325..446194	Francisella tularensis subsp. tularensis FSC198	4199081
YP_666604.1	CDS	speA	NC_008245.1	446220	447629	D	Similar to Q8A2B1 Putative arginine decarboxylase from Bacteroides thetaiotamicron (630 aa). FASTA: opt: 571 Z-score: 678.2 E(): 6.9e-30 Smith-Waterman score: 689; 28.755 identity in 546 aa overlap; putative arginine decarboxylase	446220..447629	Francisella tularensis subsp. tularensis FSC198	4199080
YP_666605.1	CDS	FTF0433	NC_008245.1	447679	447867	D	ORF ftt0433; hypothetical protein	447679..447867	Francisella tularensis subsp. tularensis FSC198	4200454
YP_666606.1	CDS	FTF0434	NC_008245.1	447848	448834	D	Similar to Q8KCB6 Hypothetical protein CT1508 from Chlorobium tepidum (347 aa). FASTA: opt: 742 Z-score: 939.4 E(): 2e-44 Smith-Waterman score: 837; 38.484 identity in 343 aa overlap PAD_porph is a possible virulence factor for P. gingivalis: PMID: 10377098 ORF ftt0434; hypothetical protein	447848..448834	Francisella tularensis subsp. tularensis FSC198	4200455
YP_666607.1	CDS	FTF0435	NC_008245.1	448836	449696	D	Similar to Q87NU4 Putative carbon-nitrogen hydrolase from Vibrio parahaemolyticus (288 aa). FASTA: opt: 1139 Z-score: 1419.0 E(): 3.8e-71 Smith-Waterman score: 1139; 57.971 identity in 276 aa overlap. Possible candidate for citrulline ureidase ORF ftt0435; carbon-nitrogen hydrolase family protein	448836..449696	Francisella tularensis subsp. tularensis FSC198	4200456
YP_666608.1	CDS	lpxH	NC_008245.1	449713	450429	R	catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase	complement(449713..450429)	Francisella tularensis subsp. tularensis FSC198	4199649
YP_666609.1	CDS	pyrE	NC_008245.1	450419	451045	R	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase	complement(450419..451045)	Francisella tularensis subsp. tularensis FSC198	4199132
YP_666610.1	CDS	mpl	NC_008245.1	451205	452575	D	Similar to MPL_ECOLI (P37773) UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diamino pimelate ligase (murein peptide ligase) from E coli (457 aa). FASTA: opt: 1392, Z-score: 1656.5, E(): 2.3e-84,Smith-Waterman score: 1392; 47.912 identity in 455 aa overlap; UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase	451205..452575	Francisella tularensis subsp. tularensis FSC198	4199851
YP_666611.1	CDS	yjfH	NC_008245.1	452572	453228	D	Similar to YJFH_ECOLI (P39290) hypothetical tRNA/rRNA methyltransferase yjfH from E. coli (243 aa). FASTA: opt: 556, Z-score: 695.5, E(): 7.5e-31 Smith-Waterman score: 556; 43.128 identity in 211 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element close to the C-terminal. It is not clear whether this insertion affects the function of the protein; tRNA/rRNA methyltransferase	452572..453228	Francisella tularensis subsp. tularensis FSC198	4199029
YP_666612.1	CDS	isftu1	NC_008245.1	453302	454086	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(453302..453760,453760..454086))	Francisella tularensis subsp. tularensis FSC198	4199629
YP_666613.1	CDS	FTF0442c	NC_008245.1	454957	456150	R	Similar to Q8EU72 Bicyclomycin resistance protein from Oceanobacillus iheyensis (412 aa). FASTA: opt: 614 Z-score: 668.2 E(): 2.5e-29 Smith-Waterman score: 614; 30.179identity in 391 aa overlap ORF ftt0442c; major facilitator transporter	complement(454957..456150)	Francisella tularensis subsp. tularensis FSC198	4199010
YP_666614.1	CDS	FTF0443	NC_008245.1	456422	457465	D	Similar to Q83C03 Conserved domain protein from Coxiella burnetii (377 aa). FASTA: opt: 359 Z-score: 409.9 E(): 6.1e-15 Smith-Waterman score: 380; 27.350 identity in 351 aa overlap ORF ftt0443; hypothetical protein	456422..457465	Francisella tularensis subsp. tularensis FSC198	4199011
YP_666615.1	CDS	tet	NC_008245.1	457536	458774	D	Similar to Q83CB9 Multidrug transporter, putative from Coxiella burnetii (412 aa). FASTA: opt: 558 Z-score: 638.9 E(): 1.1e-27 Smith-Waterman score: 558; 25.854identity in 410 aa overlap. Similar to tetA and tetC which are situated on a plasmid in E. coli; multidrug transporter (tetracycline resistance protein)	457536..458774	Francisella tularensis subsp. tularensis FSC198	4199137
YP_666616.1	CDS	FTF0446	NC_008245.1	460705	462147	D	Similar to Q83RB7 Putative transport protein from Shigella flexneri (500 aa). FASTA: opt: 567 Z-score: 573.2 E(): 4.9e-24 Smith-Waterman score: 578; 26.122 identity in 490 aa overlap ORF ftt0446; proton-dependent oligopeptide transport (POT) family protein	460705..462147	Francisella tularensis subsp. tularensis FSC198	4199012
YP_666617.1	CDS	FTF0447c	NC_008245.1	462291	463631	R	Similar to Q83DW3 Hypothetical protein from Coxiella burnetii (497 aa). FASTA: opt: 334 Z-score: 356.6 E(): 5.7e-12 Smith-Waterman score: 336; 24.129 identity in 402 aa overlap ORF ftt0447c; hypothetical protein	complement(462291..463631)	Francisella tularensis subsp. tularensis FSC198	4199013
YP_666618.1	CDS	glnS	NC_008245.1	463652	465298	R	catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase	complement(463652..465298)	Francisella tularensis subsp. tularensis FSC198	4199790
YP_666619.1	CDS	pckA	NC_008245.1	465443	467035	D	PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase	465443..467035	Francisella tularensis subsp. tularensis FSC198	4200097
YP_666620.1	CDS	mraY	NC_008245.1	467110	468207	D	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase	467110..468207	Francisella tularensis subsp. tularensis FSC198	4199853
YP_666621.1	CDS	murD	NC_008245.1	468207	469457	D	Similar to MURD_CHLCV (Q821S1) UDP-N-acetylmuramoylalanine--D-glutamate ligase from Chlamydophila caviae (419 aa) FASTA: opt: 516 Z-score: 615.2 E(): 2.2e-26 Smith-Waterman score: 549; 28.000 identity in 425 aa overlap; UDP-N-acetylmuramoylalanine--D-glutamate ligase	468207..469457	Francisella tularensis subsp. tularensis FSC198	4200107
YP_666622.1	CDS	ftsW	NC_008245.1	469467	470672	D	Similar to Q9KPG6 Cell division protein FtsW from Vibrio cholerae (398 aa). FASTA: opt: 1114 Z-score: 1237.3 E(): 5e-61 Smith-Waterman score: 1114; 44.892 identity in 372 aa overlap; cell division protein FtsW	469467..470672	Francisella tularensis subsp. tularensis FSC198	4199197
YP_666623.1	CDS	FTF0453c	NC_008245.1	470680	471486	R	Similar to Q83DW2 Hypothetical protein from Coxiella burnetii (273 aa). FASTA: opt: 554 Z-score: 648.8 E(): 3e-28 Smith-Waterman score: 554; 37.407identity in 270 aa overlap ORF ftt0453c; hypothetical protein	complement(470680..471486)	Francisella tularensis subsp. tularensis FSC198	4199014
YP_666624.1	CDS	yfdH	NC_008245.1	471585	472541	D	Similar to Q83DW4 Glycosyl transferase, group 2 family protein from Coxiella burnetii (324 aa). FASTA: opt: 896 Z-score: 1055.7 E(): 6.5e-51 Smith-Waterman score: 896; 43.189identity in 301 aa overlap; glycosyl transferase family protein	471585..472541	Francisella tularensis subsp. tularensis FSC198	4199098
YP_666625.1	CDS	FTF0455c	NC_008245.1	472933	474696	R	Similar to Q8XQM9 Probable transmembrane protein from Ralstonia solanacearum (551 aa). FASTA: opt: 683 Z-score: 749.4 E(): 7.6e-34 Smith-Waterman score: 683; 29.174 identity in 545 aa overlap ORF ftt0455c; dolichyl-phosphate-mannose-protein mannosyltransferase family protein	complement(472933..474696)	Francisella tularensis subsp. tularensis FSC198	4199015
YP_666626.1	CDS	FTF0456c	NC_008245.1	474788	475081	R	Similar to Y941_COXBU Hypothetical UPF0269 protein CBU0941 from Coxiella burnetii (90 aa). FASTA: opt: 346 Z-score: 470.4 E(): 2.6e-18 Smith-Waterman score: 346; 55.422 identity in 83 aa overlap ORF ftt0456c; hypothetical protein	complement(474788..475081)	Francisella tularensis subsp. tularensis FSC198	4199016
YP_666627.1	CDS	yccK	NC_008245.1	475072	475386	R	Similar to Q9CNM6 Hypothetical protein PM0401 from Pasteurella multocida (109 aa). initn: 382 init1: 382 opt: 382 Z-score: 511.4 bits: 99.7 E(): 1.4e-20 Smith-Waterman score: 382; 58.586identity (58.58639ngapped) in 99 aa overlap; anaerobic sulfite reductase subunit	complement(475072..475386)	Francisella tularensis subsp. tularensis FSC198	4199096
YP_666628.1	CDS	sspA	NC_008245.1	475472	476104	D	Similar to SSPA_HAESO (P31784) Stringent starvation protein A homolog from Haemophilus somnus (212 aa). FASTA: opt: 377 Z-score: 473.8 E(): 1.7e-18 Smith-Waterman score: 377; 35.106 identity in 188 aa overlap; stringent starvation protein A	475472..476104	Francisella tularensis subsp. tularensis FSC198	4199085
YP_666629.1	CDS	sohB	NC_008245.1	476116	477135	D	SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease	476116..477135	Francisella tularensis subsp. tularensis FSC198	4199079
YP_666630.1	CDS	holB	NC_008245.1	477143	478054	D	Similar to Q8D3A6 HolB protein from Wigglesworthia glossinidia brevipalpis (329 aa). FASTA: opt: 315 Z-score: 378.8 E(): 3.3e-13 Smith-Waterman score: 315; 27.304 identity in 293 aa overlap; DNA polymerase III, delta prime subunit	477143..478054	Francisella tularensis subsp. tularensis FSC198	4200198
YP_666631.1	CDS	yhbY	NC_008245.1	478065	478343	D	Similar to Q87LZ3 Putative RNA-binding protein containing KH domain from Vibrio parahaemolyticus (98 aa). FASTA: opt: 289 Z-score: 405.9 E(): 1e-14 Smith-Waterman score: 289; 52.222 identity in 90 aa overlap; RNA-binding protein	478065..478343	Francisella tularensis subsp. tularensis FSC198	4199104
YP_666632.1	CDS	hemB	NC_008245.1	478351	479325	D	catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase	478351..479325	Francisella tularensis subsp. tularensis FSC198	4200371
YP_666633.1	CDS	yibK	NC_008245.1	479329	479796	D	Similar to Q8E8X2 RNA methyltransferase, TrmH family, group 2 from Shewanella oneidensis (154 aa). FASTA: opt: 569 Z-score: 759.8 E(): 2e-34 Smith-Waterman score: 569; 57.616 identity in 151 aa overlap; tRNA/rRNA methyltransferase	479329..479796	Francisella tularensis subsp. tularensis FSC198	4199107
YP_666634.1	CDS	ansB	NC_008245.1	479914	480978	D	Similar to ASG2_HAEIN (P43843) Probable L-asparaginase periplasmic [Precursor] from Haemophilus influenzae (349 aa). FASTA: opt: 897 Z-score: 1034.7 E(): 9.6e-50 Smith-Waterman score: 897; 43.966 identity in 348 aa overlap. No signal peptide predicted; periplasmic L-asparaginase II	479914..480978	Francisella tularensis subsp. tularensis FSC198	4199425
YP_666635.1	CDS	FTF0465	NC_008245.1	481702	481890	D	ORF ftt0465; hypothetical protein	481702..481890	Francisella tularensis subsp. tularensis FSC198	4199017
YP_666636.1	CDS	argS	NC_008245.1	481942	483687	R	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase	complement(481942..483687)	Francisella tularensis subsp. tularensis FSC198	4199430
YP_666637.1	CDS	ostA1	NC_008245.1	483813	486419	D	Similar to OSTA_XYLFT (Q87AI9) Organic solvent tolerance protein from Xylella fastidiosa (792 aa). FASTA: opt: 700 Z-score: 808.7 E(): 3.7e-37 Smith-Waterman score: 775; 26.572 identity in 636 aa overlap; organic solvent tolerance protein	483813..486419	Francisella tularensis subsp. tularensis FSC198	4200087
YP_666638.1	CDS	surA	NC_008245.1	486401	487822	D	Similar to Q8ZIK4 Survival protein SurA (Peptidyl-prolyl cis-trans isomerase) from Yersinia pestis (434 aa). FASTA: opt: 532 Z-score: 586.9 E(): 8.4e-25 Smith-Waterman score: 532; 25.176 identity in 425 aa overlap; peptidyl-prolyl cis-trans isomerase	486401..487822	Francisella tularensis subsp. tularensis FSC198	4199093
YP_666639.1	CDS	ksgA	NC_008245.1	487824	488612	D	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase	487824..488612	Francisella tularensis subsp. tularensis FSC198	4199510
YP_666640.1	CDS	apaH	NC_008245.1	488624	489451	D	hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase	488624..489451	Francisella tularensis subsp. tularensis FSC198	4199426
YP_666641.1	CDS	aroD	NC_008245.1	489455	489892	D	catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase	489455..489892	Francisella tularensis subsp. tularensis FSC198	4199434
YP_666642.1	CDS	accB	NC_008245.1	489897	490370	D	Similar to BCCP_PSEAE (P37799) Biotin carboxyl carrier protein of acetyl-CoA carboxylase from Pseudomonas aeruginosa (156 aa). FASTA: opt: 466 Z-score: 537.8 E(): 4.6e-22 Smith-Waterman score: 466; 48.148 identity in 162 aa overlap; Acetyl-CoA carboxylase, biotin carboxyl carrier protein subunit	489897..490370	Francisella tularensis subsp. tularensis FSC198	4199747
YP_666643.1	CDS	accC	NC_008245.1	490435	491790	D	Similar to Q9KV62 Acetyl-CoA carboxylase, biotin carboxylase subunit from Vibrio cholerae (447 aa). FASTA: opt: 2119 Z-score: 2505.5 E(): 1.2e-131 Smith-Waterman score: 2119; 70.270 identity in 444 aa overlap; Acetyl-CoA carboxylase, biotin carboxylase subunit	490435..491790	Francisella tularensis subsp. tularensis FSC198	4199748
YP_666644.1	CDS	FTF0474	NC_008245.1	491884	492564	D	ORF ftt0474; hypothetical protein	491884..492564	Francisella tularensis subsp. tularensis FSC198	4199018
YP_666645.1	CDS	msc	NC_008245.1	492590	493708	D	Similar to Q87G16 (Q87G16) Putative membrane protein from Vibrio parahaemolyticus (365 aa). FASTA: opt: 362 Z-score: 432.0 E(): 3.6e-16 Smith-Waterman score: 412; 29.167 identity in 384 aa overlap; mechanosensitive ion channel protein	492590..493708	Francisella tularensis subsp. tularensis FSC198	4200099
YP_666646.1	CDS	poxA	NC_008245.1	493713	494636	R	Similar to Q83AR3 (Q83AR3) Lysyl-tRNA synthetase-related protein from Coxiella burnetii (321 aa). FASTA: opt: 727 Z-score: 890.9 E(): 9.9e-42 Smith-Waterman score: 727; 42.088 identity in 297 aa overlap; lysyl-tRNA synthetase	complement(493713..494636)	Francisella tularensis subsp. tularensis FSC198	4199741
YP_666647.1	CDS	birA	NC_008245.1	494633	495415	R	Similar to Q83CV0 BirA bifunctional protein from Coxiella burnetii (323 aa). FASTA: opt: 375 Z-score: 457.7 E(): 1.3e-17 Smith-Waterman score: 375; 31.004 identity in 229 aa overlap; transcription repressor BirA	complement(494633..495415)	Francisella tularensis subsp. tularensis FSC198	4200309
YP_666648.1	CDS	recJ	NC_008245.1	495412	497154	R	Similar to RECJ_HAEIN (P45112) single-stranded-DNA-specific exonuclease from Haemophilus influenzae (575 aa). FASTA: opt: 869 Z-score: 996.6 E(): 1.3e-47 Smith-Waterman score: 902; 32.028identity in 562 aa overlap; single-stranded-DNA-specific exonuclease	complement(495412..497154)	Francisella tularensis subsp. tularensis FSC198	4200605
YP_666649.1	CDS	perM	NC_008245.1	497148	498254	R	Similar to Q9I4W6 Hypothetical protein PA1007 from Pseudomonas aeruginosa (357 aa). FASTA: opt: 1016 Z-score: 1092.5 E(): 5.8e-53 Smith-Waterman score: 1016; 40.698 identity in 344 aa overlap; PerM family protein	complement(497148..498254)	Francisella tularensis subsp. tularensis FSC198	4199241
YP_666650.1	CDS	xasA	NC_008245.1	498356	499765	R	Similar to Q8YBJ1 Glutamate:gamma-aminobutyrate antiporter from Brucella melitensis (510 aa). FASTA: opt: 983 Z-score: 1079.5 E(): 3.1e-52 Smith-Waterman score: 983; 34.698 identity in 464 aa overlap; glutamate:gamma-aminobutyric acid antiporter family protein	complement(498356..499765)	Francisella tularensis subsp. tularensis FSC198	4200692
YP_666651.1	CDS	potF	NC_008245.1	499849	501030	D	Similar to Q92RX4 Probable putrescine-binding periplasmic protein from Rhizobium meliloti (364 aa). FASTA: opt: 847 Z-score: 993.2 E(): 2e-47 Smith-Waterman score: 847; 35.714 identity in 350 aa overlap; putrescine-binding periplasmic protein	499849..501030	Francisella tularensis subsp. tularensis FSC198	4199737
YP_666652.1	CDS	FTF0482c	NC_008245.1	501283	502098	R	ORF ftt0482c; lipoprotein	complement(501283..502098)	Francisella tularensis subsp. tularensis FSC198	4199019
YP_666653.1	CDS	FTF0483c	NC_008245.1	502317	503204	R	Similar to AAP95905 (AAP95905) Hypothetical protein from Haemophilus ducreyi 35000HP (342 aa). FASTA: opt: 686 Z-score: 815.5 E(): 1.6e-37 Smith-Waterman score: 686; 40.678 identity in 295 aa overlap ORF ftt0483c; hypothetical protein	complement(502317..503204)	Francisella tularensis subsp. tularensis FSC198	4199020
YP_666654.1	CDS	FTF0484	NC_008245.1	503358	504077	D	ORF ftt0484; hypothetical protein	503358..504077	Francisella tularensis subsp. tularensis FSC198	4199021
YP_666655.1	CDS	FTF0485	NC_008245.1	504145	504807	D	ORF ftt0485; hypothetical protein	504145..504807	Francisella tularensis subsp. tularensis FSC198	4199022
YP_666656.1	CDS	mutL	NC_008245.1	504815	506617	D	Similar to MUTL_RICPR (Q9ZC88) DNA mismatch repair protein mutL from Rickettsia prowazekii (595 aa). FASTA: opt: 1236 Z-score: 1435.6 E(): 4.5e-72 Smith-Waterman score: 1236; 37.291 identity in 598 aa overlap; DNA mismatch repair protein	504815..506617	Francisella tularensis subsp. tularensis FSC198	4200112
YP_666657.1	CDS	FTF0487	NC_008245.1	506974	507708	D	Similar to Q83AI9 Membrane protein,putative from Coxiella burnetii (401 aa). FASTA: 306 opt: 370 Z-score: 417.4 E(): 2.3e-15 Smith-Waterman score: 370; 30.342 identity in 234 aa overlap ORF ftt0487; hypothetical protein	506974..507708	Francisella tularensis subsp. tularensis FSC198	4199023
YP_666658.1	CDS	FTF0488c	NC_008245.1	507715	508848	R	Similar to Q83BM0 Major facilitator family transporter from Coxiella burnetii (428 aa). FASTA: opt: 319 Z-score: E(): 3.7e-11 Smith-Waterman score: 319; 21.951 identity in 369 aa overlap ORF ftt0488c; major facilitator transporter	complement(507715..508848)	Francisella tularensis subsp. tularensis FSC198	4199024
YP_666659.1	CDS	trxB	NC_008245.1	508990	509940	R	Similar to Q8ZGC9 Thioredoxin reductase from Yersinia pestis (320 aa). FASTA: opt: 1525 Z-score: 1798.2 E(): 2.9e-92 Smith-Waterman score: 1525; 70.927 identity in 313 aa overlap; thioredoxin reductase	complement(508990..509940)	Francisella tularensis subsp. tularensis FSC198	4198971
YP_666660.1	CDS	FTF0490c	NC_008245.1	510032	511249	R	Similar Q888K0 Phospholipase D family protein from Pseudomonas syringae (pv. tomato) (422 aa). FASTA: opt: 440 Z-score: 514.4 E(): 9.2e-21 Smith-Waterman score: 440; 25.840 identity in 387 aa overlap ORF ftt0490c; phospholipase D	complement(510032..511249)	Francisella tularensis subsp. tularensis FSC198	4199025
YP_666661.1	CDS	gph	NC_008245.1	511292	511966	R	Similar to Q82SZ4 Phosphoglycolate phosphatase from Nitrosomonas europaea (240 aa). FASTA: opt: 432 Z-score: 532.2 E(): 9.4e-22 Smith-Waterman score: 432; 33.486 identity in 218 aa overlap; phosphoglycolate phosphatase	complement(511292..511966)	Francisella tularensis subsp. tularensis FSC198	4200293
YP_666662.1	CDS	lysR	NC_008245.1	512007	512933	R	Similar to Q87J66 Transcriptional regulator, LysR family from Vibrio parahaemolyticus (311 aa). FASTA: opt: 675 Z-score: 768.6 E(): 6.4e-35 Smith-Waterman score: 675; 33.115 identity in 305 aa overlap; LysR family transcriptional regulator	complement(512007..512933)	Francisella tularensis subsp. tularensis FSC198	4199654
YP_666663.1	CDS	cutC	NC_008245.1	514232	514954	R	Similar Q9CNA6 Hypothetical protein PM0526 from Pasteurella multocida (244 aa). FASTA: opt: 521 Z-score: 651.2 E(): 2.2e-28 Smith-Waterman score: 521; 40.175 identity in 229 aa overlap; CutC family protein	complement(514232..514954)	Francisella tularensis subsp. tularensis FSC198	4200281
YP_666664.1	CDS	FTF0495	NC_008245.1	515287	515790	D	Similar to Q9K0Q8 Hypothetical protein NMB0526 from Neisseria meningitidis (serogroup B) (172 aa). FASTA: opt: 455 Z-score: 573.9 E(): 4.5e-24 Smith-Waterman score: 455; 42.353 identity in 170 aa overlap ORF ftt0495; hypothetical protein	515287..515790	Francisella tularensis subsp. tularensis FSC198	4199027
YP_666665.1	CDS	FTF0496	NC_008245.1	515796	516560	D	Similar to Q935B8 Hypothetical protein HCM2.0044c from Salmonella typhi (251 aa). FASTA: opt: 242 Z-score: 297.7 E(): 1.1e-08 Smith-Waterman score: 296; 28.000 identity in 250 aa overlap ORF ftt0496; hypothetical protein	515796..516560	Francisella tularensis subsp. tularensis FSC198	4199028
YP_666666.1	CDS	FTF0499	NC_008245.1	519151	519873	D	Similar to Q8ZA05 Hypothetical protein YPO4021 from Yersinia pestis (414 aa). FASTA: opt: 230 Z-score: 284.7 E(): 5.7e-08 Smith-Waterman score: 230; 24.779 identity in 226 aa overlap ORF ftt0499; hypothetical protein	519151..519873	Francisella tularensis subsp. tularensis FSC198	4199385
YP_666667.1	CDS	FTF0500	NC_008245.1	520103	520363	D	ORF ftt0500; hypothetical protein	520103..520363	Francisella tularensis subsp. tularensis FSC198	4199386
YP_666668.1	CDS	FTF0501c	NC_008245.1	520495	521535	R	Similar to Q9I0I7 Hypothetical protein PA2651 from Pseudomonas aeruginosa (352 aa). FASTA: opt: 382 Z-score: 397.1 E(): 3.2e-14 Smith-Waterman score: 382; 26.686 identity in 341 aa overlap ORF ftt0501c; hypothetical protein	complement(520495..521535)	Francisella tularensis subsp. tularensis FSC198	4199387
YP_666669.1	CDS	FTF0502c	NC_008245.1	521919	522344	R	ORF ftt0502c; hypothetical protein	complement(521919..522344)	Francisella tularensis subsp. tularensis FSC198	4199388
YP_666670.1	CDS	sucD	NC_008245.1	522456	523328	R	Similar to Q9JUS9 Putative succinyl-CoA synthetase alpha from Neisseria meningitidis (serogroup A) (296 aa). FASTA: opt: 1574 Z-score: 1817.5 E(): 2.4e-93 Smith-Waterman score: 1574; 81.661identity in 289 aa overlap; succinyl-CoA synthetase, alpha subunit	complement(522456..523328)	Francisella tularensis subsp. tularensis FSC198	4199090
YP_666671.1	CDS	sucC	NC_008245.1	523360	524523	R	catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta	complement(523360..524523)	Francisella tularensis subsp. tularensis FSC198	4199089
YP_666672.1	CDS	FTF0505	NC_008245.1	524693	526606	D	ORF ftt0505; hypothetical protein	524693..526606	Francisella tularensis subsp. tularensis FSC198	4199389
YP_666673.1	CDS	FTF0506c	NC_008245.1	526614	526928	R	ORF ftt0506c; hypothetical protein	complement(526614..526928)	Francisella tularensis subsp. tularensis FSC198	4199390
YP_666674.1	CDS	FTF0507	NC_008245.1	527587	528354	D	Similar to Q9X610 BcfH from Salmonella typhimurium (269 aa). FASTA: opt: 305 Z-score: 371.4 E(): 8.5e-13 Smith-Waterman score: 305; 31.122 identity in 196 aa overlap ORF ftt0507; lipoprotein	527587..528354	Francisella tularensis subsp. tularensis FSC198	4199391
YP_666675.1	CDS	dusA	NC_008245.1	528361	529344	R	Similar to Y926_SYNY3 (P72872) Hypothetical protein sll0926 from Synechocystis sp. (strain PCC 6803) (334 aa). FASTA: opt: 1129 Z-score: 1337.0 E(): 1.4e-66 Smith-Waterman score: 1129; 51.911 identity in 314 aa overlap; tRNA-dihydrouridine synthase A	complement(528361..529344)	Francisella tularensis subsp. tularensis FSC198	4199362
YP_666676.1	CDS	FTF0509c	NC_008245.1	529378	530178	R	Similar to Q8DBN3 Conserved hypothetical protein from Vibrio vulnificus (184 aa). FASTA: opt: 275 Z-score: 356.8 E(): 5.5e-12 Smith-Waterman score: 275; 30.208 identity in 192 aa overlap ORF ftt0509c; hypothetical protein	complement(529378..530178)	Francisella tularensis subsp. tularensis FSC198	4199392
YP_666677.1	CDS	gyrB	NC_008245.1	530354	532771	D	Similar to GYRB_SALTY (Q60008) DNA gyrase subunit B from Salmonella typhimurium (803 aa). FASTA: opt: 3370 Z-score: 3873.3 E(): 7.5e-208 Smith-Waterman score: 3370; 63.321 identity in 807 aa overlap; DNA gyrase subunit B	530354..532771	Francisella tularensis subsp. tularensis FSC198	4200368
YP_666678.1	CDS	FTF0511	NC_008245.1	532901	533764	D	with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS	532901..533764	Francisella tularensis subsp. tularensis FSC198	4199393
YP_666679.2	CDS	FTF0512	NC_008245.1	533767	534306	D	with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT	533767..534306	Francisella tularensis subsp. tularensis FSC198	4199394
YP_666680.1	CDS	isftu1	NC_008245.1	534410	535194	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(534410..534868,534868..535194))	Francisella tularensis subsp. tularensis FSC198	4199630
YP_666681.1	CDS	FTF0515	NC_008245.1	536411	536587	D	ORF ftt0515; hypothetical protein	536411..536587	Francisella tularensis subsp. tularensis FSC198	4199395
YP_666682.1	CDS	prmA	NC_008245.1	541265	542110	D	Similar to Q9CLW2 PrmA (Ribosomal protein L11 methyltransferase) from Pasteurella multocida (293 aa). FASTA: opt: 572 Z-score: 685.5 E(): 2.7e-30 Smith-Waterman score: 580; 33.677 identity in 291 aa overlap; 50S ribosomal protein L11 methyltransferase	541265..542110	Francisella tularensis subsp. tularensis FSC198	4199942
YP_666683.1	CDS	FTF0519	NC_008245.1	542100	543083	D	Similar to Q9KGG5 Transcriptional regulator involved in nitrogen regulation, NifR3/Smm1 family from Bacillus halodurans (334 aa). FASTA: opt: 1134 Z-score: 1336.1 E(): 1.6e-66 Smith-Waterman score: 1134; 52.484 identity in 322 aa overlap ORF ftt0519; Nif3 family protein	542100..543083	Francisella tularensis subsp. tularensis FSC198	4199398
YP_666684.1	CDS	FTF0520	NC_008245.1	543313	543906	D	ORF ftt0520; hypothetical protein	543313..543906	Francisella tularensis subsp. tularensis FSC198	4199399
YP_666685.1	CDS	FTF0522	NC_008245.1	544433	545410	D	Similar to Q8EGY1 Type I restriction-modification system, M subunit, putative from Shewanella oneidensis (684 aa). FASTA: opt: 278 Z-score: 287.3 E(): 4.1e-08 Smith-Waterman score: 291; 31.081 identity in 222 aa overlap ORF ftt0522; hypothetical protein	544433..545410	Francisella tularensis subsp. tularensis FSC198	4199056
YP_666686.1	CDS	FTF0523	NC_008245.1	545535	546761	D	Similar to Q89Z57 Type I restriction enzyme EcoAI specificity protein from Bacteroides thetaiotamicron (474 aa). FASTA: opt: 208 Z-score: 239.0 E(): 2e-05 Smith-Waterman score: 246; 24.363 identity in 353 aa overlap ORF ftt0523; hypothetical protein	545535..546761	Francisella tularensis subsp. tularensis FSC198	4199057
YP_666687.1	CDS	FTF0524	NC_008245.1	547003	547389	D	Similar to Q8KBB0 Hypothetical protein CT1879 from Chlorobium tepidum (193 aa). FASTA: opt: 467 Z-score: 629.2 E(): 3.7e-27 Smith-Waterman score: 467; 60.656 identity in 122 aa overlap ORF ftt0524; hypothetical protein	547003..547389	Francisella tularensis subsp. tularensis FSC198	4199058
YP_666688.1	CDS	FTF0525	NC_008245.1	547436	548092	D	Similar to RA50_THEVO DNA double-strand break repair rad50 ATPase from Thermoplasma volcanicum (895 aa). FASTA: opt: 188 Z-score: 215.6 E(): 0.0004 Smith-Waterman score: 188; 25.926 identity in 216 aa overlap. Similarity to N terminal domain ORF ftt0525; hypothetical protein	547436..548092	Francisella tularensis subsp. tularensis FSC198	4199059
YP_666689.1	CDS	FTF0526	NC_008245.1	548098	548304	D	ORF ftt0526; hypothetical protein	548098..548304	Francisella tularensis subsp. tularensis FSC198	4199060
YP_666690.1	CDS	FTF0527	NC_008245.1	548325	549128	D	ORF ftt0527; hypothetical protein	548325..549128	Francisella tularensis subsp. tularensis FSC198	4199061
YP_666691.1	CDS	FTF0528	NC_008245.1	549125	549502	D	ORF ftt0528; hypothetical protein	549125..549502	Francisella tularensis subsp. tularensis FSC198	4199062
YP_666692.1	CDS	FTF0530c	NC_008245.1	550577	551179	R	Similar to Q97FB4 Intracellular protease/amidase related enzyme from Clostridium acetobutylicum (201 aa). FASTA: opt: 703 Z-score: 884.5 E(): 2.2e-41 Smith-Waterman score: 703; 51.531 identity in 196 aa overlap ORF ftt0530c; DJ-1/PfpI family protein	complement(550577..551179)	Francisella tularensis subsp. tularensis FSC198	4199063
YP_666693.1	CDS	grxC	NC_008245.1	553181	554413	R	Similar to (glutaredoxin 3) Q8ZJM8 Glutaredoxin 3 from Yersinia pestis (82 aa). FASTA: opt: 181 Z-score: 263.7 E(): 8.5e-07 Smith-Waterman score: 181; 40.260 identity in 77 aa overlap,(ribonucleoside-diphosphate reductase) Q8QYZ8 Ribonucleoside-diphosphate reductase,beta subunit-like protein from Rana tigrina ranavirus (387 aa). FASTA: opt: 1124 Z-score: 1382.6 E(): 4.1e-69 Smith-Waterman score: 1124; 51.703 identity in 323 aa overlap; bifunctional gluaredoxin/ribonucleoside-diphosphate reductase subunit beta	complement(553181..554413)	Francisella tularensis subsp. tularensis FSC198	4200303
YP_666694.1	CDS	grxA	NC_008245.1	554420	554680	R	Similar to GLR1_ECOLI (P00277) Glutaredoxin 1 from Escherichia coli (85 aa). FASTA: opt: 191 Z-score: 274.9 E(): 2e-07 Smith-Waterman score: 191; 40.000identity in 80 aa overlap; glutaredoxin	complement(554420..554680)	Francisella tularensis subsp. tularensis FSC198	4200301
YP_666695.1	CDS	nrdA	NC_008245.1	554684	556456	R	Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha	complement(554684..556456)	Francisella tularensis subsp. tularensis FSC198	4200242
YP_666696.1	CDS	mdh	NC_008245.1	556660	557619	R	Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase	complement(556660..557619)	Francisella tularensis subsp. tularensis FSC198	4199663
YP_666697.1	CDS	FTF0536	NC_008245.1	557767	558282	D	ORF ftt0536; hypothetical protein	557767..558282	Francisella tularensis subsp. tularensis FSC198	4199065
YP_666698.1	CDS	FTF0537	NC_008245.1	558298	558933	D	Similar to Q8PD67 Ubiquinone biosynthesis protein from Xanthomonas campestris (217 aa). FASTA: opt: 710 Z-score: 878.4 E(): 4.9e-41 Smith-Waterman score: 710; 51.887 identity in 212 aa overlap (2-211:8-217) ORF ftt0537; ubiquinone biosynthesis protein	558298..558933	Francisella tularensis subsp. tularensis FSC198	4199066
YP_666699.1	CDS	FTF0538c	NC_008245.1	558942	559511	R	Similar to Q87LS3 Hypothetical protein from Vibrio parahaemolyticus (203 aa). FASTA: opt: 267 Z-score: 350.1 E(): 1.3e-11 Smith-Waterman score: 320; 31.795 identity in 195 aa overlap ORF ftt0538c; lipoprotein	complement(558942..559511)	Francisella tularensis subsp. tularensis FSC198	4199067
YP_666700.1	CDS	FTF0540c	NC_008245.1	560336	561826	R	ORF ftt0540c; hypothetical protein	complement(560336..561826)	Francisella tularensis subsp. tularensis FSC198	4199069
YP_666701.1	CDS	yqaB	NC_008245.1	561881	562480	R	Similar to YQAB_ECOLI (P77475) Hypothetical protein yqaB from Escherichia coli (188 aa). FASTA: opt: 336 Z-score: 422.2 E(): 1.3e-15 Smith-Waterman score: 336; 33.889 identity in 180 aa overlap; haloacid dehalogenase	complement(561881..562480)	Francisella tularensis subsp. tularensis FSC198	4199034
YP_666702.1	CDS	FTF0543	NC_008245.1	563221	564597	D	ORF ftt0543; hypothetical protein	563221..564597	Francisella tularensis subsp. tularensis FSC198	4199071
YP_666703.1	CDS	phnA	NC_008245.1	564703	565035	D	Similar to PHNA_ECOLI PhnA protein from Escherichia coli (111 aa). FASTA: opt: 521 Z-score: 674.6 E(): 1.1e-29 Smith-Waterman score: 521; 66.972identity in 109 aa overlap; phosphonoacetate hydrolase	564703..565035	Francisella tularensis subsp. tularensis FSC198	4199726
YP_666704.1	CDS	FTF0545	NC_008245.1	565041	565256	D	ORF ftt0545; hypothetical protein	565041..565256	Francisella tularensis subsp. tularensis FSC198	4199072
YP_666705.1	CDS	FTF0546	NC_008245.1	565260	565871	D	ORF ftt0546; hypothetical protein	565260..565871	Francisella tularensis subsp. tularensis FSC198	4199073
YP_666706.1	CDS	FTF0547	NC_008245.1	566226	566759	D	ORF ftt0547; hypothetical protein	566226..566759	Francisella tularensis subsp. tularensis FSC198	4199074
YP_666707.1	CDS	dnaQ	NC_008245.1	566811	567503	D	Similar to Q83EK2 DNA polymerase III, epsilon subunit from Coxiella burnetii (232 aa). FASTA: opt: 699 Z-score: 870.8 E(): 1.3e-40 Smith-Waterman score: 699; 49.550 identity in 222 aa overlap; DNA polymerase III subunit epsilon	566811..567503	Francisella tularensis subsp. tularensis FSC198	4199358
YP_666708.1	CDS	vanY	NC_008245.1	567497	567970	D	Similar to Q87AM4 Peptidase (202 aa). FASTA: opt: 481 Z-score: 603.7 E(): 9.8e-26 Smith-Waterman score: 481; 50.000 identity in 142 aa overlap; D-alanyl-D-alanine carboxypeptidase	567497..567970	Francisella tularensis subsp. tularensis FSC198	4200139
YP_666709.1	CDS	FTF0550	NC_008245.1	567930	569366	D	Similar to Q8EHZ3 TPR domain protein from Shewanella oneidensis (466 aa). FASTA: opt: 304 Z-score: 346.2 E(): 2.2e-11 Smith-Waterman score: 331; 23.333 identity) in 480 aa overlap ORF ftt0550; hypothetical protein	567930..569366	Francisella tularensis subsp. tularensis FSC198	4199075
YP_666710.1	CDS	FTF0552	NC_008245.1	570799	572295	D	Similar to Q8P9Q7 Aldehyde dehydrogenase from Xanthomonas campestris (510 aa). FASTA: opt: 1972 Z-score: 2329.9 E(): 6.9e-122 Smith-Waterman score: 1972; 60.285 identity in 491 aa overlap ORF ftt0552; aldehyde dehydrogenase	570799..572295	Francisella tularensis subsp. tularensis FSC198	4200384
YP_666711.1	CDS	FTF0553	NC_008245.1	572300	573079	D	Similar to Q8EJ53 Conserved hypothetical protein from Shewanella oneidensis (267 aa). FASTA: opt: 859 Z-score: 1057.9 E(): 4.9e-51 Smith-Waterman score: 859; 52.809 identity in 267 aa overlap ORF ftt0553; hypothetical protein	572300..573079	Francisella tularensis subsp. tularensis FSC198	4200385
YP_666712.1	CDS	FTF0554	NC_008245.1	573163	573435	D	Similar to Q99SH0 Hypothetical protein SAV2087 from Stafylococcus aureus (97 aa). FASTA: opt: 243 Z-score: 331.6 E(): 1.4e-10 Smith-Waterman score: 243; 45.455 identity in 77 aa overlap ORF ftt0554; hypothetical protein	573163..573435	Francisella tularensis subsp. tularensis FSC198	4200386
YP_666713.1	CDS	FTF0555	NC_008245.1	573449	574180	D	Similar to Q930P5 Hypothetical protein RA0150 from Rhizobium meliloti (262 aa). FASTA: opt: 924 Z-score: 1048.2 E(): 1.7e-50 Smith-Waterman score: 924; 54.202 identity in 238 aa overlap. Some similarity to glutaredoxin ORF ftt0555; hypothetical protein	573449..574180	Francisella tularensis subsp. tularensis FSC198	4200387
YP_666714.1	CDS	oxyR	NC_008245.1	574183	575052	R	Similar to O06466 Oxidative stress transcriptional regulator from Xanthomonas campestris (313 aa). FASTA: opt: 707 Z-score: 842.2 E(): 5.1e-39 Smith-Waterman score: 707; 36.207 identity in 290 aa overlap; oxidative stress transcriptional regulator	complement(574183..575052)	Francisella tularensis subsp. tularensis FSC198	4200089
YP_666715.1	CDS	FTF0557	NC_008245.1	575150	575674	D	Similar to Q92MY1 Hypothetical protein R02467 from Rhizobium meliloti (180 aa). FASTA: opt: 821 Z-score: 1055.0 E(): 7.2e-51 Smith-Waterman score: 821; 66.092 identity in 174 aa overlap ORF ftt0557; AhpC/TSA family protein	575150..575674	Francisella tularensis subsp. tularensis FSC198	4200388
YP_666716.1	CDS	FTF0558	NC_008245.1	575677	576288	D	Similar to Q8XU62 Hypothetical protein RSc3331 from Ralstonia solanacearum (201 aa). FASTA: opt: 602 Z-score: 724.0 E(): 2e-32 Smith-Waterman score: 602; 48.020 identity in 202 aa overlap ORF ftt0558; short chain dehydrogenase	575677..576288	Francisella tularensis subsp. tularensis FSC198	4200389
YP_666717.1	CDS	cmk	NC_008245.1	576305	576970	R	Similar to KCY_PASMU (P57875) Cytidylate kinase from Pasteurella multocida (227 aa). FASTA: opt: 748 Z-score: 879.9 E(): 4.1e-41 Smith-Waterman score: 748; 53.425 identity in 219 aa overlap; cytidylate kinase	complement(576305..576970)	Francisella tularensis subsp. tularensis FSC198	4200269
YP_666718.1	CDS	serC	NC_008245.1	576957	578009	R	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase	complement(576957..578009)	Francisella tularensis subsp. tularensis FSC198	4200742
YP_666719.1	CDS	isftu1	NC_008245.1	578329	579113	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(578329..578655,578655..579113)	Francisella tularensis subsp. tularensis FSC198	4199631
YP_666720.1	CDS	potG	NC_008245.1	579495	580616	D	Similar to Q8EHF2 Polyamine ABC transporter,ATP-binding protein from Shewanella oneidensis (378 aa). FASTA: opt: 1366 Z-score: 1557.5 E(): 7.3e-79 Smith-Waterman score: 1366; 55.496 identity in 373 aa overlap; polyamine transporter, ABC transporter,ATP-binding protein	579495..580616	Francisella tularensis subsp. tularensis FSC198	4199738
YP_666721.1	CDS	potH	NC_008245.1	580580	581497	D	Similar to Q8FJE8 Putrescine transport system permease protein from Escherichia coli (314 aa). FASTA: opt: 949 Z-score: 1040.4 E(): 4.7e-50 Smith-Waterman score: 949; 43.878 identity in 294 aa overlap; polyamine transporter, subunit H, ABC transporter, membrane protein	580580..581497	Francisella tularensis subsp. tularensis FSC198	4199739
YP_666722.1	CDS	potI	NC_008245.1	581511	582317	D	Similar to Q8EHF0 Polyamine ABC transporter,permease protein from Shewanella oneidensis (271 aa). FASTA: opt: 873 Z-score: 1010.7 E(): 2.1e-48 Smith-Waterman score: 873; 46.241 identity in 266 aa overlap; polyamine transporter, subunit I, ABC transporter, membrane protein	581511..582317	Francisella tularensis subsp. tularensis FSC198	4199740
YP_666723.1	CDS	isftu2	NC_008245.1	582461	583204	R	ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa).; transposase	complement(582461..583204)	Francisella tularensis subsp. tularensis FSC198	4199288
YP_666724.1	CDS	FTF0566	NC_008245.1	583350	583616	D	ORF ftt0566; hypothetical protein	583350..583616	Francisella tularensis subsp. tularensis FSC198	4200390
YP_666725.1	CDS	FTF0568	NC_008245.1	585822	586472	D	Similar to Q26545 Phosphoserine phosphohydrolase-like protein trans-spliced from Schistosoma mansoni (223 aa). FASTA: opt: 319 Z-score: 380.8 E(): 2.5e-13 Smith-Waterman score: 319; 29.493 identity in 217 aa overlap. Similar to eukaryotic proteins. Historical HGT-event? ORF ftt0568; hypothetical protein	585822..586472	Francisella tularensis subsp. tularensis FSC198	4200392
YP_666726.1	CDS	FTF0569c	NC_008245.1	586461	587483	R	Similar to Q8P3T2 Integral membrane protein from Xanthomonas campestris (347 aa). FASTA: opt: 906 Z-score: 1071.1 E(): 9e-52 Smith-Waterman score: 906; 41.739 identity in 345 aa overlap ORF ftt0569c; hypothetical protein	complement(586461..587483)	Francisella tularensis subsp. tularensis FSC198	4200393
YP_666727.1	CDS	FTF0570	NC_008245.1	587563	587961	D	ORF ftt0570; hypothetical protein	587563..587961	Francisella tularensis subsp. tularensis FSC198	4200394
YP_666728.1	CDS	FTF0571	NC_008245.1	587973	588680	D	Partially similar to Q96F61 Hypothetical protein from Homo sapiens (409 aa). FASTA: opt: 403 Z-score: 516.3 E(): 7.3e-21 Smith-Waterman score: 403; 34.171 identity in 199 aa overlap ORF ftt0571; hypothetical protein	587973..588680	Francisella tularensis subsp. tularensis FSC198	4200395
YP_666729.1	CDS	FTF0572	NC_008245.1	588805	590259	D	Similar to Q8Z269 Putative PTR2 family transport protein from Salmonella typhi (489 aa). FASTA: opt: 729 Z-score: 778.1 E(): 1.9e-35 Smith-Waterman score: 770; 30.524identity in 439 aa overlap ORF ftt0572; proton-dependent oligopeptide transport (POT) family protein	588805..590259	Francisella tularensis subsp. tularensis FSC198	4200396
YP_666730.1	CDS	alr	NC_008245.1	590310	591407	D	Similar to Q81EB9 Alanine racemase from Bacillus cereus (408 aa). FASTA: opt: 573 Z-score: 679.1 E(): 6.2e-30 Smith-Waterman score: 573; 29.863 identity in 365 aa overlap; alanine racemase	590310..591407	Francisella tularensis subsp. tularensis FSC198	4199760
YP_666731.1	CDS	pheA	NC_008245.1	593182	594024	D	Similar to Q8KBW6 Prephenate dehydratase from chlorobium tepidum (280 aa). FASTA: opt: 624 Z-score: 792.7 E(): 2.9e-36 Smith-Waterman score: 624; 38.489 identity in 278 aa overlap; prephenate dehydratase	593182..594024	Francisella tularensis subsp. tularensis FSC198	4199246
YP_666732.1	CDS	FTF0576	NC_008245.1	594050	594718	D	Similar to Q894N2 Putative zinc metallopeptidase from Clostridium tetani (236 aa). FASTA: opt: 434 Z-score: 526.0 E(): 2.1e-21 Smith-Waterman score: 434; 36.245 identity in 229 aa overlap ORF ftt0576; hypothetical protein	594050..594718	Francisella tularensis subsp. tularensis FSC198	4200398
YP_666733.1	CDS	sdaA	NC_008245.1	594774	596147	D	Similar to Q8EEW4 L-serine dehydratase 1 from Shewanella oneidensis (458 aa). FASTA: opt: 1442 Z-score: 1806.4 E(): 1e-92 Smith-Waterman score: 1442; 48.922 identity in 464 aa overlap; L-serine dehydratase 1	594774..596147	Francisella tularensis subsp. tularensis FSC198	4200726
YP_666734.1	CDS	csdB	NC_008245.1	596250	597473	D	Similar to Q8ZDZ4 Putative selenocysteine lyase from Yersinia pestis (406 aa). FASTA: opt: 1343 Z-score: 1645.0 E(): 9.9e-84 Smith-Waterman score: 1343; 48.507 identity in 402 aa overlap; selenocysteine lyase	596250..597473	Francisella tularensis subsp. tularensis FSC198	4200277
YP_666735.1	CDS	FTF0579	NC_008245.1	597494	597850	D	Similar to AAP95950 HesB family protein from Haemophilus ducreyi (107 aa). FASTA: opt: 288 Z-score: 392.8 E(): 5.5e-14 Smith-Waterman score: 288; 41.121 identity in 107 aa overlap ORF ftt0579; hesB family protein	597494..597850	Francisella tularensis subsp. tularensis FSC198	4200399
YP_666736.1	CDS	FTF0580	NC_008245.1	597864	598415	D	Similar to Q83BY3 Hypothetical protein from Coxiella burnetii (180 aa). FASTA: opt: 593 Z-score: 750.6 E(): 6.4e-34 Smith-Waterman score: 593; 48.045 identity in 179 aa overlap ORF ftt0580; hypothetical protein	597864..598415	Francisella tularensis subsp. tularensis FSC198	4200400
YP_666737.1	CDS	coaD	NC_008245.1	598427	598915	D	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase	598427..598915	Francisella tularensis subsp. tularensis FSC198	4200270
YP_666738.1	CDS	fdx	NC_008245.1	598920	599165	D	ferredoxin. Identical to Q47937 Ferredoxin from Francisella novicida. Similar to Q88AH4 Ferredoxin from pseudomonas syringae (83 aa). FASTA: opt: 431 Z-score: 563.2 E(): 1.8e-23 Smith-Waterman score: 431; 65.432 identity in 81 aa overlap; ferredoxin	598920..599165	Francisella tularensis subsp. tularensis FSC198	4199407
YP_666739.1	CDS	fopA1	NC_008245.1	599272	600453	D	No transmembrane helix predicted; outer membrane associated protein	599272..600453	Francisella tularensis subsp. tularensis FSC198	4199419
YP_666740.1	CDS	FTF0584	NC_008245.1	601115	604486	D	ORF ftt0584; hypothetical protein	601115..604486	Francisella tularensis subsp. tularensis FSC198	4200457
YP_666741.1	CDS	FTF0586	NC_008245.1	605855	606433	D	Similar to Q9YCL9 Hypothetical protein APE1239 from Aeropyrum pernix (221 aa). FASTA: opt: 238 Z-score: 303.8 E(): 5e-09 Smith-Waterman score: 238; 25.683 identity in 183 aa overlap. Weakly conserved. ORF ftt0586; hypothetical protein	605855..606433	Francisella tularensis subsp. tularensis FSC198	4200459
YP_666742.1	CDS	isftu2	NC_008245.1	606857	607600	R	ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa).; transposase	complement(606857..607600)	Francisella tularensis subsp. tularensis FSC198	4199289
YP_666743.1	CDS	aroA	NC_008245.1	607763	609040	D	Similar to AROA_VIBPA (Q87QX9) 3-phosphoshikimate 1-carboxyvinyltransferase from Vibrio parahaemolyticus (426 aa). FASTA: opt: 928 Z-score: 1157.4 E(): 1.4e-56 Smith-Waterman score: 928; 36.916 identity in 428 aa overlap; 3-phosphoshikimate 1-carboxyvinyltransferase	607763..609040	Francisella tularensis subsp. tularensis FSC198	4199431
YP_666744.1	CDS	FTF0589	NC_008245.1	609043	609633	D	ORF ftt0589; hypothetical protein	609043..609633	Francisella tularensis subsp. tularensis FSC198	4200460
YP_666745.1	CDS	rnhA	NC_008245.1	609584	610066	D	Similar to RNH_PSEAE (Q9I2S9) Ribonuclease H from Pseudomonas aeruginosa (148 aa). FASTA: opt: 673 Z-score: 830.4 E(): 2.3e-38 Smith-Waterman score: 673; 62.937 identity in 143 aa overlap; ribonuclease H	609584..610066	Francisella tularensis subsp. tularensis FSC198	4200766
YP_666746.1	CDS	ansA	NC_008245.1	610068	611105	D	Similar to Q8EEG1 L-asparaginase I from Shewanella oneidensis (337 aa). FASTA: opt: 1041 Z-score: 1293.4 E(): 3.7e-64 Smith-Waterman score: 1041; 49.258identity in 337 aa overlap; L-asparaginase	610068..611105	Francisella tularensis subsp. tularensis FSC198	4199424
YP_666747.1	CDS	cynT	NC_008245.1	611176	611862	D	Similar to Q87AM3 Carbonic anhydrase from xylella fastidiosa (220 aa). FASTA: opt: 577 Z-score: 733.9 E(): 5.5e-33 Smith-Waterman score: 722; 45.536 identity in 224 aa overlap; carbonic anhydrase	611176..611862	Francisella tularensis subsp. tularensis FSC198	4200286
YP_666748.1	CDS	FTF0593c	NC_008245.1	612149	612754	R	ORF ftt0593c; hypothetical protein	complement(612149..612754)	Francisella tularensis subsp. tularensis FSC198	4200461
YP_666749.1	CDS	FTF0594c	NC_008245.1	612818	613690	R	Similar to Q87N89 Hypothetical protein from Vibrio parahaemolyticus (344 aa). FASTA: opt: 706 Z-score: 859.6 E(): 5.5e-40 Smith-Waterman score: 706; 42.160 identity in 287 aa overlap ORF ftt0594c; hypothetical protein	complement(612818..613690)	Francisella tularensis subsp. tularensis FSC198	4200462
YP_666750.1	CDS	rubA	NC_008245.1	613699	613869	R	Similar to Q88C68 Rubredoxin from Pseudomonas putida (55 aa). FASTA: opt: 334 Z-score: 465.9 E(): 4.6e-18 Smith-Waterman score: 334; 78.431 identity in 51 aa overlap; rubredoxin	complement(613699..613869)	Francisella tularensis subsp. tularensis FSC198	4198963
YP_666751.1	CDS	FTF0596c	NC_008245.1	613956	614573	R	ORF ftt0596c; hypothetical protein	complement(613956..614573)	Francisella tularensis subsp. tularensis FSC198	4200463
YP_666752.1	CDS	FTF0597	NC_008245.1	614685	616079	D	Similar to Q9K5Z6 Hypothetical UPF0061 protein BH393 from Bacillus halodurans (492 aa). FASTA: opt: 1251 Z-score: 1519.2 E(): 1e-76 Smith-Waterman score: 1357; 48.233 identity in 481 aa overlap ORF ftt0597; hypothetical protein	614685..616079	Francisella tularensis subsp. tularensis FSC198	4200464
YP_666753.1	CDS	FTF0598c	NC_008245.1	616111	617391	R	Similar to Q8XLU3 Probable transmembrane symporter from Clostridium perfringens (435 aa). FASTA: opt: 881 Z-score: 961.9 E(): 1.1e-45 Smith-Waterman score: 881; 33.721identity in 430 aa overlap ORF ftt0598c; Sodium-dicarboxylate symporter family protein	complement(616111..617391)	Francisella tularensis subsp. tularensis FSC198	4200465
YP_666754.1	CDS	FTF0599	NC_008245.1	617587	618615	D	Similar to Q9AAR1 SIS domain protein from Caulobacter crescentus (358 aa). FASTA: opt: 864 Z-score: 1052.1 E(): 1e-50 Smith-Waterman score: 864; 42.353 identity in 340 aa overlap. Putative Glucosamine-fructose-6-phosphate aminotransferase ORF ftt0599; SIS domain-containing protein	617587..618615	Francisella tularensis subsp. tularensis FSC198	4200466
YP_666755.1	CDS	FTF0601	NC_008245.1	620200	620319	D	ORF ftt0601; hypothetical protein	620200..620319	Francisella tularensis subsp. tularensis FSC198	4200468
YP_666756.1	CDS	FTF0602c	NC_008245.1	620946	622424	R	ORF ftt0602c; hypothetical protein	complement(620946..622424)	Francisella tularensis subsp. tularensis FSC198	4200469
YP_666757.1	CDS	FTF0603	NC_008245.1	622984	623163	D	ORF ftt0603; hypothetical protein	622984..623163	Francisella tularensis subsp. tularensis FSC198	4200470
YP_666758.1	CDS	FTF0604	NC_008245.1	623681	624115	D	Similar to Q9CNR2 NhaP NA+/H+ antiporter Conserved hypothetical membrane protein from Pasteurella multocida (441 aa). FASTA: opt: 315 Z-score: 391.3 E(): 6.6e-14 Smith-Waterman score: 315; 39.850 identity in 133 aa overlap. Matches to a central part of an Nhap protein ORF ftt0604; hypothetical protein	623681..624115	Francisella tularensis subsp. tularensis FSC198	4200471
YP_666759.1	CDS	FTF0605c	NC_008245.1	624301	624489	R	ORF ftt0605c; hypothetical protein	complement(624301..624489)	Francisella tularensis subsp. tularensis FSC198	4200472
YP_666760.1	CDS	ispG	NC_008245.1	625293	626510	D	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase	625293..626510	Francisella tularensis subsp. tularensis FSC198	4199303
YP_666761.1	CDS	FTF0608	NC_008245.1	626525	627103	D	Similar to Q9KHC2 Hypothetical 27.0 kDa protein from secondary endosymbiont of Glycaspis brimblecombei (244 aa). FASTA: opt: 467 Z-score: 605.3 E(): 8e-26 Smith-Waterman score: 467; 44.751identity in 181 aa overlap ORF ftt0608; hypothetical protein	626525..627103	Francisella tularensis subsp. tularensis FSC198	4200474
YP_666762.1	CDS	FTF0609	NC_008245.1	627254	629047	D	Similar to Q83F75 Peptidase, M24 family protein from Coxiella burnetii (597 aa). FASTA: opt: 1665 Z-score: 1963.9 E(): 1.7e-101 Smith-Waterman score: 1665; 45.286 identity in 594 aa overlap ORF ftt0609; peptidase, M24 family protein	627254..629047	Francisella tularensis subsp. tularensis FSC198	4200475
YP_666763.1	CDS	FTF0610	NC_008245.1	629145	630209	D	Similar to Q8DFB3 DNA/RNA endonuclease G from Vibrio vulnificus (247 aa). FASTA: opt: 682 Z-score: 838.7 E(): 8e-39 Smith-Waterman score: 682; 46.311 identity in 244 aa overlap ORF ftt0610; DNA/RNA endonuclease family protein	629145..630209	Francisella tularensis subsp. tularensis FSC198	4200476
YP_666764.1	CDS	FTF0611c	NC_008245.1	630200	631063	R	Similar to Q9L6I3 Extended-spectrum beta-lactamase BES-1 from Serratia marcescens (292 aa).FASTA: opt: 621 Z-score: 723.1 E(): 2.2e-32 Smith-Waterman score: 621; 34.397 identity in 282 aa overlap ORF ftt0611c; beta-lactamase	complement(630200..631063)	Francisella tularensis subsp. tularensis FSC198	4200611
YP_666765.1	CDS	FTF0612	NC_008245.1	631499	632311	D	ORF ftt0612; hypothetical protein	631499..632311	Francisella tularensis subsp. tularensis FSC198	4200612
YP_666766.1	CDS	FTF0613c	NC_008245.1	632632	633051	R	This ORF is longer. ORF ftt0613c; hypothetical protein	complement(632632..633051)	Francisella tularensis subsp. tularensis FSC198	4200613
YP_666767.1	CDS	FTF0614c	NC_008245.1	633297	634787	R	Similar to Q820B4 Apolipoprotein N-acyltransferase from Coxiella burnetii (485 aa). FASTA: opt: 984 Z-score: 1082.0 E(): 2.2e-52 Smith-Waterman score: 984; 35.903 identity in 493 aa overlap ORF ftt0614c; apolipoprotein N-acyltransferase	complement(633297..634787)	Francisella tularensis subsp. tularensis FSC198	4200614
YP_666768.1	CDS	FTF0615c	NC_008245.1	634787	635647	R	Similar to Q8EHP0 Magnesium and cobalt efflux protein CorC from Shewanella oneidensis (291 aa). FASTA: opt: 676 Z-score: 772.4 E(): 3.9e-35 Smith-Waterman score: 676; 39.847 identity in 261 aa overlap ORF ftt0615c; metal ion transporter protein	complement(634787..635647)	Francisella tularensis subsp. tularensis FSC198	4200615
YP_666769.1	CDS	FTF0616c	NC_008245.1	635619	636125	R	Similar to Q8EHN9 Hypothetical UPF0054 protein SO117 from Shewanella oneidensis (153 aa). FATSA: opt: 433 Z-score: 547.4 E(): 1.3e-22 Smith-Waterman score: 433; 44.025identity in 159 aa overlap ORF ftt0616c; hypothetical protein	complement(635619..636125)	Francisella tularensis subsp. tularensis FSC198	4200616
YP_666770.1	CDS	phoH	NC_008245.1	636100	637083	R	Simliar to Q87VY0 PhoH-like protein from Pseudomonas syringae (340 aa). FASTA: opt: 1132 Z-score: 1306.4 E(): 7.1e-65 Smith-Waterman score: 1132; 52.923 identity in 325 aa overlap; phoH-like protein	complement(636100..637083)	Francisella tularensis subsp. tularensis FSC198	4199727
YP_666771.1	CDS	yleA	NC_008245.1	637102	638430	R	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase	complement(637102..638430)	Francisella tularensis subsp. tularensis FSC198	4199033
YP_666772.1	CDS	FTF0619	NC_008245.1	638653	639327	D	Similar to O67476 O-methyltransferase from Aquifex aeolicus (212 aa). FASTA: opt: 382 Z-score: 477.6 E(): 1e-18 Smith-Waterman score: 382; 33.495 identity in 206 aa overlap. ORF ftt0619; o-methyltransferase family protein	638653..639327	Francisella tularensis subsp. tularensis FSC198	4200617
YP_666773.1	CDS	FTF0620	NC_008245.1	639336	640079	D	Similar to Q8PER3 Acid phosphatase from Xanthomonas axonopodis (310 aa). FASTA: opt: 238 Z-score: 293.2 E(): 1.9e-08 Smith-Waterman score: 238; 24.583 identity in 240 aa overlap. ORF ftt0620; HAD superfamily protein	639336..640079	Francisella tularensis subsp. tularensis FSC198	4200618
YP_666774.1	CDS	tdk	NC_008245.1	640095	640688	D	catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase	640095..640688	Francisella tularensis subsp. tularensis FSC198	4199136
YP_666775.1	CDS	FTF0622c	NC_008245.1	640731	641195	R	ORF ftt0622c; hypothetical protein	complement(640731..641195)	Francisella tularensis subsp. tularensis FSC198	4200619
YP_666776.1	CDS	tig	NC_008245.1	641350	642666	D	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor	641350..642666	Francisella tularensis subsp. tularensis FSC198	4199145
YP_666777.1	CDS	clpP	NC_008245.1	642692	643297	D	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit	642692..643297	Francisella tularensis subsp. tularensis FSC198	4200267
YP_666778.1	CDS	clpX	NC_008245.1	643321	644574	D	binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX	643321..644574	Francisella tularensis subsp. tularensis FSC198	4200268
YP_666779.1	CDS	lon	NC_008245.1	644599	646923	D	Similar to Q8Z8V0 Lon protease from Salmonella typhi (784 aa). FASTA: opt: 2734 Z-score: 2797.3 E(): 6.4e-148 Smith-Waterman score: 2734; 54.450 identity in 764 aa overlap.; DNA-binding, ATP-dependent protease La	644599..646923	Francisella tularensis subsp. tularensis FSC198	4199562
YP_666780.1	CDS	hupB	NC_008245.1	647010	647282	D	Similar to Q93TM3 Histone-like protein HU form B from Pseudomonas putida (strain KT2440) (90 aa). FASTA: opt: 380 Z-score: 519.0 E(): 5.2e-21 Smith-Waterman score: 380; 68.539 identity in 89 aa overlap.; histone-like protein HU form B	647010..647282	Francisella tularensis subsp. tularensis FSC198	4200650
YP_666781.1	CDS	FTF0628	NC_008245.1	647394	648824	D	Similar to PPID_BUCAP (Q8K987) Peptidyl-prolyl cis-trans isomerase from Buchnera aphidicola (subsp. Schizaphis graminum) (621 aa). FASTA: opt: 298 Z-score: 309.1E(): 2.5e-09 Smith-Waterman score: 298; 23.362 identity in 351 aa overlap. 200 aa shorter (in C-term) than most of the homologs. ORF ftt0628; hypothetical protein	647394..648824	Francisella tularensis subsp. tularensis FSC198	4200620
YP_666782.1	CDS	miaA	NC_008245.1	648825	649751	D	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase	648825..649751	Francisella tularensis subsp. tularensis FSC198	4199844
YP_666783.1	CDS	hfq	NC_008245.1	649862	650191	D	Similar to HFQ_PASMU (Q9CMC6) Hfq protein from Pasteurella multocida (95 aa). FASTA: opt: 384 Z-score: 504.4 E(): 3.3e-20 Smith-Waterman score: 384; 68.182 identity in 88 aa overlap. Plays a role in degradation of RNA transcripts.; host factor I for bacteriophage Q beta replication	649862..650191	Francisella tularensis subsp. tularensis FSC198	4200193
YP_666784.1	CDS	hflX	NC_008245.1	650243	651550	D	Similar to Q87VJ5 GTP-binding protein HflX from Pseudomonas syringae (pv. tomato) (433 aa). FASTA: opt: 1331 Z-score: 1520.3 E(): 8.6e-77 Smith-Waterman score: 1331; 49.302 identity in 430 aa overlap. Together with HflC-HflK involved in stability of phage lambda cII repressor; protease, GTP-binding subunit	650243..651550	Francisella tularensis subsp. tularensis FSC198	4200192
YP_666785.1	CDS	FTF0632c	NC_008245.1	651561	652751	R	Similar to O53772 Putative oxidoreductase (Monooxygenase) from Mycobacterium tuberculosis (388 aa). FASTA: opt: 832 Z-score: 997.9 E(): 1.1e-47 Smith-Waterman score: 832; 35.550 identity in 391 aa overlap. ORF ftt0632c; hypothetical protein	complement(651561..652751)	Francisella tularensis subsp. tularensis FSC198	4200621
YP_666786.1	CDS	hflK	NC_008245.1	652923	653990	D	Similar to Q8FAK7 HflK protein from Escherichia coli (419 aa). FASTA: opt: 843 Z-score: 932.9 E(): 4.5e-44 Smith-Waterman score: 843; 40.0 identity in 330 aa overlap. With HflC, part of modulator for protease specific for FtsH phage lambda cII repressor.; hypothetical protein	652923..653990	Francisella tularensis subsp. tularensis FSC198	4200382
YP_666787.1	CDS	hflC	NC_008245.1	653992	654918	D	Similar to Q8EJ66 HflC protein from Shewanella oneidensis (297 aa). FASTA: opt: 799 Z-score: 895.3 E(): 5.6e-42 Smith-Waterman score: 799; 42.466 identity in 292 aa overlap. With HflK, part of modulator for protease specific for FtsH phage lambda cII repressor.; hypothetical protein	653992..654918	Francisella tularensis subsp. tularensis FSC198	4200381
YP_666788.1	CDS	wzb	NC_008245.1	654919	655404	D	Similar to O35016 YFKJ protein from Bacillus subtilis (156 aa). FASTA: opt: 391 Z-score: 494.5 E(): 1.2e-19 Smith-Waterman score: 391; 38.608 identity in 158 aa overlap.; low molecular weight (LMW) phosphotyrosine protein phosphatase	654919..655404	Francisella tularensis subsp. tularensis FSC198	4200689
YP_666789.1	CDS	engB	NC_008245.1	655401	655994	D	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC	655401..655994	Francisella tularensis subsp. tularensis FSC198	4199676
YP_666790.1	CDS	FTF0638	NC_008245.1	657431	657781	D	Putative fragment. Weak similarity to leuA LE12_METJA (Q58595) 2-isopropylmalate synthase 2 from Methanococcus jannaschii (518 aa). FASTA: opt: 119 Z-score: 151.8 E(): 1.5 Smith-Waterman score: 119; 26.316 identity in 114 aa overlap (6-115:356-467). Next downstream ORF also has similarity to leuA. ORF ftt0638; hypothetical protein	657431..657781	Francisella tularensis subsp. tularensis FSC198	4200622
YP_666791.1	CDS	FTF0639	NC_008245.1	657823	657933	D	Putative fragment. Weak similarity to leuA LE12_METJA (Q58595) 2-isopropylmalate synthase 2 from Methanococcus jannaschii (518 aa). FASTA: opt: 86 Z-score: 142.0 E(): 5.1 Smith-Waterman score: 86; 50.000 identity in 32 aa overlap (1-32:479-510). Next upstream ORF also have similarity to leuA. ORF ftt0639; hypothetical protein	657823..657933	Francisella tularensis subsp. tularensis FSC198	4200623
YP_666792.1	CDS	ilvD	NC_008245.1	657957	659612	D	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase	657957..659612	Francisella tularensis subsp. tularensis FSC198	4200664
YP_666793.1	CDS	ilvH	NC_008245.1	661475	661792	D	Similar to Q8A610 Acetohydroxyacid synthase small subunit (187 aa). FASTA: opt: 159 Z-score: 221.3 E(): 0.0002 Smith-Waterman score: 159; 33.333 identity in 75 aa overlap.; acetolactate synthase small subunit	661475..661792	Francisella tularensis subsp. tularensis FSC198	4200666
YP_666794.1	CDS	mfd	NC_008245.1	662987	666412	R	Similar to Q9CM06 Mfd from Pasteurella multocida (1145 aa). FASTA: opt: 3312 Z-score: 3697.7 E(): 4.5e-198 Smith-Waterman score: 3312; 44.794 identity in 1143 aa overlap.; transcription-repair coupling factor	complement(662987..666412)	Francisella tularensis subsp. tularensis FSC198	4199841
YP_666795.1	CDS	FTF0645c	NC_008245.1	666457	667143	R	Similar to YCCA_ECOLI (P06967) Hypothetical protein yccA from Escherichia coli (219 aa). FASTA: opt: 588 Z-score: 603.2 E(): 1.1e-25 Smith-Waterman score: 588; 48.416 identity in 221 aa overlap. ORF ftt0645c; hypothetical protein	complement(666457..667143)	Francisella tularensis subsp. tularensis FSC198	4200624
YP_666796.1	CDS	FTF0646c	NC_008245.1	667259	668518	R	ORF ftt0646c; hypothetical protein	complement(667259..668518)	Francisella tularensis subsp. tularensis FSC198	4200625
YP_666797.1	CDS	FTF0647c	NC_008245.1	668518	668949	R	Similar to Q82WE7 Hypothetical protein from Nitrosomonas europaea (164 aa). FASTA: opt: 383 Z-score: 490.4 E(): 2e-19 Smith-Waterman score: 383; 41.606 identity in 137 aa overlap. ORF ftt0647c; hypothetical protein	complement(668518..668949)	Francisella tularensis subsp. tularensis FSC198	4200626
YP_666798.1	CDS	nth	NC_008245.1	668946	669584	R	Similar to Q9HYB4 Endonuclease III from Pseudomonas aeruginosa (212 aa). FASTA: opt: 916 Z-score: 1153.9 E(): 2.2e-56 Smith-Waterman score: 916; 67.308identity in 208 aa overlap.; endonuclease III	complement(668946..669584)	Francisella tularensis subsp. tularensis FSC198	4200243
YP_666799.1	CDS	rnfB	NC_008245.1	669577	670206	R	Similar to Q83B23 4Fe-4S binding domain protein from Coxiella burnetii (213 aa). FASTA: opt: 552 Z-score: 680.7 E(): 5e-30 Smith-Waterman score: 552; 42.788 identity in 208 aa overlap.; Iron-sulfur cluster-binding protein	complement(669577..670206)	Francisella tularensis subsp. tularensis FSC198	4200764
YP_666800.1	CDS	grxB	NC_008245.1	670208	670852	R	cofactor involved in the reduction of disulfides; glutaredoxin	complement(670208..670852)	Francisella tularensis subsp. tularensis FSC198	4200302
YP_666801.1	CDS	FTF0651	NC_008245.1	670914	672482	D	Similar to Q9L9P6 IraB from Legionella pneumophila (501 aa). FASTA: opt: 1486 Z-score: 1640.1 E(): 1.8e-83 Smith-Waterman score: 1486; 46.708 identity in 486 aa overlap. ORF ftt0651; proton-dependent oligopeptide transport (POT) family protein	670914..672482	Francisella tularensis subsp. tularensis FSC198	4200627
YP_666802.1	CDS	ftnA	NC_008245.1	672485	672982	R	Similar to Q899N4 Ferritin from Clostridium tetani (169 aa). FASTA: opt: 527 Z-score: 679.5 E(): 5.9e-30 Smith-Waterman score: 527; 45.783identity in 166 aa overlap.; Ferritin-like protein	complement(672485..672982)	Francisella tularensis subsp. tularensis FSC198	4199191
YP_666803.1	CDS	lipA	NC_008245.1	673189	674172	D	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase	673189..674172	Francisella tularensis subsp. tularensis FSC198	4199554
YP_666804.1	CDS	elbB	NC_008245.1	674202	674861	D	Similar to Q87IN9 Sigma cross-reacting protein 27A from Vibrio parahaemolyticus (216 aa). FASTA: opt: 683 Z-score: 873.4 E(): 9.3e-41 Smith-Waterman score: 683; 49.074 identity in 216 aa overlap.; isoprenoid biosynthesis protein with amidotransferase-like domain	674202..674861	Francisella tularensis subsp. tularensis FSC198	4199671
YP_666805.1	CDS	FTF0655	NC_008245.1	674877	675623	D	Similar to YO32_SHEON (Q8EEF0) Hypothetical UPF0082 protein SO2432 from Shewanella oneidensis (248 aa). FASTA: opt: 1090 Z-score: 1308.8 E(): 5.2e-65 Smith-Waterman score: 1090; 64.516 identity in 248 aa overlap. ORF ftt0655; hypothetical protein	674877..675623	Francisella tularensis subsp. tularensis FSC198	4200628
YP_666806.1	CDS	ruvC	NC_008245.1	675699	676235	D	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase	675699..676235	Francisella tularensis subsp. tularensis FSC198	4198967
YP_666807.1	CDS	ruvA	NC_008245.1	677520	678173	D	plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA	677520..678173	Francisella tularensis subsp. tularensis FSC198	4198965
YP_666808.1	CDS	FTF0659	NC_008245.1	678199	679611	D	Similar to Q87TH5 Conserved hypothetical protein from Vibrio parahaemolyticus (514 aa). FASTA: opt: 1129 Z-score: 1083.4 E(): 1.9e-52 Smith-Waterman score: 1132; 42.000 identity in 450 aa overlap ORF ftt0659; DNA recombination protein RmuC family protein	678199..679611	Francisella tularensis subsp. tularensis FSC198	4199479
YP_666809.1	CDS	FTF0660	NC_008245.1	679660	680247	D	ORF ftt0660; hypothetical protein	679660..680247	Francisella tularensis subsp. tularensis FSC198	4199480
YP_666810.1	CDS	FTF0661c	NC_008245.1	680269	680565	R	Similar to Q82LF3 Hypothetical protein from Streptomyces avermitilis (109 aa). FASTA: opt: 260 Z-score: 364.1 E(): 2.2e-12 Smith-Waterman score: 260; 47.778 identity in 90 aa overlap. The homologs are of different sizes. ORF ftt0661c; hypothetical protein	complement(680269..680565)	Francisella tularensis subsp. tularensis FSC198	4199481
YP_666811.1	CDS	FTF0662c	NC_008245.1	680728	681111	R	Similar to Q9KMT3 Hypothetical protein VCA0237 from Vibrio cholerae (189 aa). FASTA: opt: 308 Z-score: 400.0 E(): 2.2e-14 Smith-Waterman score: 308; 42.857 identity in 112 aa overlap. ORF ftt0662c; hypothetical protein	complement(680728..681111)	Francisella tularensis subsp. tularensis FSC198	4199482
YP_666812.1	CDS	FTF0663	NC_008245.1	681224	682036	D	ORF ftt0663; hypothetical protein	681224..682036	Francisella tularensis subsp. tularensis FSC198	4199483
YP_666813.1	CDS	hdc	NC_008245.1	682023	683159	R	catalyzes the formation of histamine from L-histidine; histidine decarboxylase	complement(682023..683159)	Francisella tularensis subsp. tularensis FSC198	4200369
YP_666814.1	CDS	FTF0665c	NC_008245.1	683267	683872	R	Similar to Q88IX8 Class II aldolase/adducin domain protein from Pseudomonas putida (strain KT2440) (251 aa). FASTA: opt: 472 Z-score: 599.3 E(): 1.7e-25 Smith-Waterman score: 472; 38.579identity in 197 aa overlap. ORF ftt0665c; aldolase/adducin class II family protein	complement(683267..683872)	Francisella tularensis subsp. tularensis FSC198	4199484
YP_666815.1	CDS	FTF0666c	NC_008245.1	683963	684544	R	Similar to Q896H4 DNA-3-methyladenine glycosylase from Clostridium tetani (203 aa). FASTA: opt: 451 Z-score: 589.0 E(): 6.4e-25 Smith-Waterman score: 451; 42.784 identity in 194 aa overlap. ORF ftt0666c; methylpurine-DNA glycosylase family protein	complement(683963..684544)	Francisella tularensis subsp. tularensis FSC198	4199485
YP_666816.1	CDS	FTF0667	NC_008245.1	684672	685175	D	ORF ftt0667; hypothetical protein	684672..685175	Francisella tularensis subsp. tularensis FSC198	4199486
YP_666817.1	CDS	FTF0668	NC_008245.1	685175	685807	D	Similar to Q8A546 Putative membrane transporter involved in nicotinamide mononucleotide transport from Bacteroides thetaiotaomicron (188 aa). FASTA: opt: 333 Z-score: 403.8 E(): 1.3e-14 Smith-Waterman score: 333; 29.016identity in 193 aa overlap. ORF ftt0668; nicotinamide mononucleotide transport (NMT) family protein	685175..685807	Francisella tularensis subsp. tularensis FSC198	4199487
YP_666818.1	CDS	FTF0669	NC_008245.1	685905	687080	D	Similar to Q8GRF6 MagA protein from Magnetospirillum magnetotacticum (Aquaspirillum magnetotacticum) (432 aa). FASTA: opt: 769 Z-score: 826.0 E(): 4.1e-38 Smith-Waterman score: 769; 31.635identity in 373 aa overlap. ORF ftt0669; Sodium/hydrogen exchanger family protein	685905..687080	Francisella tularensis subsp. tularensis FSC198	4199488
YP_666819.1	CDS	FTF0670c	NC_008245.1	687413	687877	R	ORF ftt0670c; hypothetical protein	complement(687413..687877)	Francisella tularensis subsp. tularensis FSC198	4199489
YP_666820.1	CDS	FTF0671	NC_008245.1	688190	689470	D	Similar to Q83DX6 Major facilitator family transporter from Coxiella burnetii (421 aa). FASTA: opt: 689 Z-score: 731.9 E(): 7.1e-33 Smith-Waterman score: 689; 29.197identity in 411 aa overlap. ORF ftt0671; major facilitator transporter	688190..689470	Francisella tularensis subsp. tularensis FSC198	4199490
YP_666821.1	CDS	FTF0673c	NC_008245.1	690742	691749	R	Similar to Q8DF84 Predicted deacylase from Vibrio vulnificus (352 aa). FASTA: opt: 789 Z-score: 951.5 E(): 4.2e-45 Smith-Waterman score: 789; 34.328 identity in 335 aa overlap. ORF ftt0673c; hypothetical protein	complement(690742..691749)	Francisella tularensis subsp. tularensis FSC198	4199492
YP_666822.1	CDS	prsA	NC_008245.1	691960	692928	D	Similar to KPRS_RALSO (Q8Y2E1) Ribose-phosphate pyrophosphokinase from Ralstonia solanacearum (Pseudomonas solanacearum) (316 aa). FASTA: opt: 1269 Z-score: 1520.3 E(): 8.6e-77 Smith-Waterman score: 1269; 58.413 identity in 315 aa overlap.; ribose-phosphate pyrophosphokinase	691960..692928	Francisella tularensis subsp. tularensis FSC198	4199945
YP_666823.1	CDS	rplY	NC_008245.1	693028	693318	D	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25	693028..693318	Francisella tularensis subsp. tularensis FSC198	4199001
YP_666824.1	CDS	FTF0676	NC_008245.1	693414	694673	D	Similar to Q83E77 Hypothetical protein from Coxiella burnetii (417 aa). FASTA: opt: 1049 Z-score: 1211.5 E(): 1.4e-59 Smith-Waterman score: 1049; 40.049 identity in 407 aa overlap. ORF ftt0676; hypothetical protein	693414..694673	Francisella tularensis subsp. tularensis FSC198	4199493
YP_666825.1	CDS	FTF0677c	NC_008245.1	694878	695654	R	Similar to Q8Z984 Putative methyltransferase from Salmonella typhi (256 aa). FASTA: opt: 707 Z-score: 818.1 E(): 1.1e-37 Smith-Waterman score: 707; 42.570 identity in 249 aa overlap. ORF ftt0677c; hypothetical protein	complement(694878..695654)	Francisella tularensis subsp. tularensis FSC198	4199494
YP_666826.1	CDS	FTF0678c	NC_008245.1	696263	696538	R	ORF ftt0678c; hypothetical protein	complement(696263..696538)	Francisella tularensis subsp. tularensis FSC198	4199495
YP_666827.1	CDS	FTF0679c	NC_008245.1	696553	697644	R	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD	complement(696553..697644)	Francisella tularensis subsp. tularensis FSC198	4199496
YP_666828.1	CDS	pth	NC_008245.1	697663	698238	R	Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase	complement(697663..698238)	Francisella tularensis subsp. tularensis FSC198	4199948
YP_666829.1	CDS	blaA	NC_008245.1	698231	699115	R	Similar to BLAC_YEREN (Q01166) Beta-lactamase precursor from Yersinia enterocolitica (294 aa). FASTA: opt: 670 Z-score: 829.7 E(): 2.5e-38 Smith-Waterman score: 670; 36.268 identity in 284 aa overlap.; Beta-lactamase class A	complement(698231..699115)	Francisella tularensis subsp. tularensis FSC198	4200310
YP_666830.1	CDS	FTF0682c	NC_008245.1	699124	699969	R	ORF ftt0682c; hypothetical protein	complement(699124..699969)	Francisella tularensis subsp. tularensis FSC198	4199497
YP_666831.1	CDS	pilD	NC_008245.1	700009	700827	R	Similar to Q888U2 Type IV pilus prepilin peptidase PilD from Pseudomonas syringae (pv. tomato) (290 aa). FASTA: opt: 784 Z-score: 898.0 E(): 4e-42 Smith-Waterman score: 784; 44.531identity in 256 aa overlap. Cleaves the leader peptide of the fiber building block proteins and methylates the resulting N-terminal residue.; Type IV pili leader peptidase and methylase	complement(700009..700827)	Francisella tularensis subsp. tularensis FSC198	4199731
YP_666832.1	CDS	sthA	NC_008245.1	700831	702246	R	catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase	complement(700831..702246)	Francisella tularensis subsp. tularensis FSC198	4199086
YP_666833.1	CDS	FTF0685c	NC_008245.1	702500	703483	R	Similar to KCH_ECOLI (P31069) Putative potassium channel protein (417 aa). FASTA: opt: 381 Z-score: 423.3 E(): 1.1e-15 Smith-Waterman score: 381; 31.203identity in 266 aa overlap. ORF ftt0685c; potassium channel protein	complement(702500..703483)	Francisella tularensis subsp. tularensis FSC198	4199036
YP_666834.1	CDS	FTF0686c	NC_008245.1	703563	704867	R	Similar to Q83E30 Proton/peptide symporter family protein from Coxiella burnetii (492 aa). FASTA: opt: 609 Z-score: 644.8 E(): 5e-28 Smith-Waterman score: 609; 26.545 identity in 437 aa overlap. The start is approx 55 aa later than the homologs. ORF ftt0686c; proton-dependent oligopeptide transport (POT) family protein	complement(703563..704867)	Francisella tularensis subsp. tularensis FSC198	4199037
YP_666835.1	CDS	hslU	NC_008245.1	705114	706481	R	heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU	complement(705114..706481)	Francisella tularensis subsp. tularensis FSC198	4200208
YP_666836.1	CDS	hslV	NC_008245.1	706489	707040	R	heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit	complement(706489..707040)	Francisella tularensis subsp. tularensis FSC198	4200209
YP_666837.1	CDS	FTF0689	NC_008245.1	707232	707981	D	ORF ftt0689; hypothetical protein	707232..707981	Francisella tularensis subsp. tularensis FSC198	4199038
YP_666838.1	CDS	lplA	NC_008245.1	707984	708886	R	Similar to Q9KS71 Lipoate-protein ligase A from Vibrio cholerae (338 aa). FASTA: opt: 699 Z-score: 831.1 E(): 2.1e-38 Smith-Waterman score: 699; 38.545identity in 275 aa overlap.; lipoate-protein ligase A	complement(707984..708886)	Francisella tularensis subsp. tularensis FSC198	4199566
YP_666839.1	CDS	tyrS	NC_008245.1	708999	710189	D	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase	708999..710189	Francisella tularensis subsp. tularensis FSC198	4198975
YP_666840.1	CDS	isftu1	NC_008245.1	710690	711474	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(710690..711148,711148..711474))	Francisella tularensis subsp. tularensis FSC198	4199632
YP_666841.1	CDS	mutM	NC_008245.1	711545	712369	R	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase	complement(711545..712369)	Francisella tularensis subsp. tularensis FSC198	4200113
YP_666842.1	CDS	FTF0694	NC_008245.1	712463	714562	D	Similar to AAP18158 2-acyl-glycerophospho-ethanolamine acyltransferase,acyl-acyl-carrier protein synthetase from Shigella flexneri (719 aa). FASTA: opt: 735 Z-score: 862.5 E(): 3.8e-40 Smith-Waterman score: 826; 33.661identity in 508 aa overlap. n. b. No match between aa 1 and 196. Several domains missing compared to AAP18158 ORF ftt0694; hypothetical protein	712463..714562	Francisella tularensis subsp. tularensis FSC198	4199039
YP_666843.1	CDS	mraW	NC_008245.1	714568	715485	D	Similar to AAP95225 S-adenosyl-methyltransferase MraW from Haemophilus ducreyi (313 aa). FASTA: opt: 918 Z-score: 1107.1 E(): 8.9e-54 Smith-Waterman score: 918; 49.677identity in 310 aa overlap.; S-adenosyl-methyltransferase MraW	714568..715485	Francisella tularensis subsp. tularensis FSC198	4199852
YP_666844.1	CDS	FTF0696	NC_008245.1	715482	715832	D	Weak similarity to cell division protein ftsL. ORF ftt0696; hypothetical protein	715482..715832	Francisella tularensis subsp. tularensis FSC198	4199040
YP_666845.1	CDS	ftsI	NC_008245.1	715825	717519	D	Similar to Q83F33 Penicillin-binding protein 3 from Coxiella burnetii (548 aa). FASTA: opt: 1361 Z-score: 1597.9 E(): 4.1e-81 Smith-Waterman score: 1361; 40.325 identity in 553 aa overlap.; penicillin binding protein (peptidoglycan synthetase)	715825..717519	Francisella tularensis subsp. tularensis FSC198	4199194
YP_666846.1	CDS	rpsO	NC_008245.1	717625	717891	D	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15	717625..717891	Francisella tularensis subsp. tularensis FSC198	4198953
YP_666847.1	CDS	pnp	NC_008245.1	717948	720029	D	Similar to Q83D87 Polyribonucleotide nucleotidyltransferase from Coxiella burnetii (696 aa). FASTA: opt: 2437 Z-score: 2800.2 E(): 4.4e-148 Smith-Waterman score: 2437; 54.401identity in 693 aa overlap.; polynucleotide phosphorylase/polyadenylase	717948..720029	Francisella tularensis subsp. tularensis FSC198	4199735
YP_666848.1	CDS	FTF0700	NC_008245.1	720035	720385	D	essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA	720035..720385	Francisella tularensis subsp. tularensis FSC198	4199041
YP_666849.1	CDS	kdsA	NC_008245.1	720395	721243	D	catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase	720395..721243	Francisella tularensis subsp. tularensis FSC198	4199506
YP_666850.1	CDS	udk	NC_008245.1	721254	721919	D	functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase	721254..721919	Francisella tularensis subsp. tularensis FSC198	4198981
YP_666851.1	CDS	rpoZ	NC_008245.1	721912	722130	D	Similar to RPOZ_PSEPK (Q88C82) Probable DNA-directed RNA polymerase omega chain from Pseudomonas putida (strain KT2440) (87 aa). FASTA: opt: 194 Z-score: 293.6 E(): 1.8e-08 Smith-Waterman score: 194; 52.857 identity in 70 aa overlap.; DNA-directed RNA polymerase subunit omega	721912..722130	Francisella tularensis subsp. tularensis FSC198	4200332
YP_666852.1	CDS	FTF0704	NC_008245.1	722395	722967	D	ORF ftt0704; hypothetical protein	722395..722967	Francisella tularensis subsp. tularensis FSC198	4199042
YP_666853.1	CDS	rumA	NC_008245.1	723056	724405	D	in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase	723056..724405	Francisella tularensis subsp. tularensis FSC198	4198964
YP_666854.1	CDS	FTF0707	NC_008245.1	725336	726130	D	Similar to Q9CK00 Hypothetical protein PM1838 from Pasteurella multocida (234 aa). FASTA: opt: 456 Z-score: 507.2 E(): 2.3e-20 Smith-Waterman score: 456; 34.483identity in 232 aa overlap. ORF ftt0707; nicotinamide mononucleotide transport (NMT) family protein	725336..726130	Francisella tularensis subsp. tularensis FSC198	4199043
YP_666855.1	CDS	FTF0708	NC_008245.1	726218	727471	D	Similar to Q83BD8 Major facilitator family transporter from Coxiella burnetii (411 aa). FASTA: opt: 868 Z-score: 941.6 E(): 1.5e-44 Smith-Waterman score: 868; 37.912identity in 364 aa overlap. ORF ftt0708; major facilitator transporter	726218..727471	Francisella tularensis subsp. tularensis FSC198	4199044
YP_666856.1	CDS	eno	NC_008245.1	727580	728950	D	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase	727580..728950	Francisella tularensis subsp. tularensis FSC198	4199677
YP_666857.1	CDS	ftsB	NC_008245.1	728958	729248	D	Similar to FTSB_VIBPA (Q87LQ1) Cell division protein ftsB homolog from Vibrio parahaemolyticus (93 aa). FASTA: opt: 198 Z-score: 273.8 E(): 2.3e-07 Smith-Waterman score: 198; 37.209 identity in 86 aa overlap.; cell division protein	728958..729248	Francisella tularensis subsp. tularensis FSC198	4199193
YP_666858.1	CDS	ispD	NC_008245.1	729238	729927	D	Similar to ISPD_PASMU (P57953) 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (238 aa). FASTA: opt: 506 Z-score: 656.8 E(): 1.1e-28 Smith-Waterman score: 506; 39.381 identity in 226 aa overlap.; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	729238..729927	Francisella tularensis subsp. tularensis FSC198	4199300
YP_666859.1	CDS	sdaC1	NC_008245.1	729932	731194	R	Similar to SDAC_HAEIN (P44615) Serine transporter from Haemophilus influenzae (412 aa). FASTA: opt: 785 Z-score: 854.1 E(): 1.1e-39 Smith-Waterman score: 785; 33.099 identity in 426 aa overlap.; serine transporter	complement(729932..731194)	Francisella tularensis subsp. tularensis FSC198	4200727
YP_666860.1	CDS	tdh	NC_008245.1	731196	732251	R	converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase	complement(731196..732251)	Francisella tularensis subsp. tularensis FSC198	4199135
YP_666861.1	CDS	kbl	NC_008245.1	732274	733470	R	catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase	complement(732274..733470)	Francisella tularensis subsp. tularensis FSC198	4199500
YP_666862.1	CDS	FTF0715	NC_008245.1	734003	736285	D	Similar to Q9ZIX2 Chitinase c from Pseudoalteromonas sp. S9 (869 aa). FASTA: opt: 331 Z-score: 370.4 E(): 9.6e-13 Smith-Waterman score: 583; 24.111 identity in 900 aa overlap. The homologs are of varying sizes. ORF ftt0715; chitinase family 18 protein	734003..736285	Francisella tularensis subsp. tularensis FSC198	4199045
YP_666863.1	CDS	upp	NC_008245.1	736464	737108	D	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase	736464..737108	Francisella tularensis subsp. tularensis FSC198	4198984
YP_666864.1	CDS	FTF0718	NC_008245.1	738116	738460	D	ORF ftt0718; hypothetical protein	738116..738460	Francisella tularensis subsp. tularensis FSC198	4199046
YP_666865.1	CDS	FTF0719	NC_008245.1	738517	739740	D	Aa 139-320 identical to AAP97846 Hypothetical protein (Fragment) from Francisella tularensis ssp. tularensis strain SchuS4 (184 aa). Similar to Q881T0 Proline/betaine transporter from Pseudomonas syringae (pv. tomato) (438 aa). FASTA: opt: 561 Z-score: 633.8 E(): 2.1e-27 Smith-Waterman score: 561; 25.616 identity in 406 aa overlap. ORF ftt0719; major facilitator transporter	738517..739740	Francisella tularensis subsp. tularensis FSC198	4199047
YP_666866.1	CDS	dgt	NC_008245.1	739724	741049	R	Similar to DGT1_VIBPA (Q87R73) Deoxyguanosinetriphosphate triphosphohydrolase-like protein from Vibrio parahaemolyticus (440 aa). FASTA: opt: 587 Z-score: 683.8 E(): 3.4e-30 Smith-Waterman score: 661; 33.781identity in 447 aa overlap.; deoxyguanosinetriphosphate triphosphohydrolase	complement(739724..741049)	Francisella tularensis subsp. tularensis FSC198	4199348
YP_666867.1	CDS	katG	NC_008245.1	741153	743378	R	Similar to CATA_YERPE (Q9X6B0) Peroxidase/catalase (EC 1.11.1.6) from Yersinia pestis (737 aa). FASTA: opt: 3041 Z-score: 3508.0 E(): 1.7e-187 Smith-Waterman score: 3041; 59.189 identity in 740 aa overlap.; peroxidase/catalase	complement(741153..743378)	Francisella tularensis subsp. tularensis FSC198	4199499
YP_666868.1	CDS	isftu1	NC_008245.1	744242	745026	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(744242..744700,744700..745026))	Francisella tularensis subsp. tularensis FSC198	4199633
YP_666869.1	CDS	FTF0723c	NC_008245.1	745333	746121	R	Similar to Q88H18 Oxidoreductase, short chain dehydrogenase/reductase family Pseudomonas putida (strain KT2440) (248 aa). FASTA: opt: 792 Z-score: 881.9 E(): 3.1e-41 Smith-Waterman score: 792; 47.984 identity in 248 aa overlap. ORF ftt0723c; short-chain dehydrogenase	complement(745333..746121)	Francisella tularensis subsp. tularensis FSC198	4199048
YP_666870.1	CDS	glpT	NC_008245.1	747524	748840	R	Similar to Q81V41 Glycerol-3-phosphate transporter from Bacillus anthracis (strain Ames) (449 aa). FASTA: opt: 1382 Z-score: 1521.3 E(): 7.6e-77 Smith-Waterman score: 1382; 48.268identity in 433 aa overlap.; glycerol-3-phosphate transporter	complement(747524..748840)	Francisella tularensis subsp. tularensis FSC198	4199798
YP_666871.1	CDS	FTF0726c	NC_008245.1	748947	749981	R	Similar to Q89FW5 Blr6584 protein from Bradyrhizobium japonicum (342 aa). FASTA: opt: 636 Z-score: 743.1 E(): 1.7e-33 Smith-Waterman score: 743; 36.336identity in 333 aa overlap. ORF ftt0726c; glycerophosphoryl diester phosphodiesterase family protein	complement(748947..749981)	Francisella tularensis subsp. tularensis FSC198	4199049
YP_666872.1	CDS	FTF0727	NC_008245.1	750119	750799	D	Similar to Q83FA0 Lipoprotein, putative from Coxiella burnetii (326 aa). FASTA: opt: 255 Z-score: 290.7 E(): 2.7e-08 Smith-Waterman score: 255; 26.606 identity in 218 aa overlap. n. b. The ORF is 100 aa shorter than all homologs (C-term). ORF ftt0727; hypothetical protein	750119..750799	Francisella tularensis subsp. tularensis FSC198	4199050
YP_666873.1	CDS	ybhF	NC_008245.1	751072	752004	D	Similar to Q89II5 ABC transporter ATP-binding protein (310 aa). FASTA: opt: 1060 Z-score: 1223.8 E(): 2.8e-60 Smith-Waterman score: 1060; 54.605 identity in 304 aa overlap.; ABC transporter ATP-binding protein	751072..752004	Francisella tularensis subsp. tularensis FSC198	4200704
YP_666874.1	CDS	ybhR	NC_008245.1	752001	753119	D	Similar to Q8Y316 Probable transmembrane protein from Ralstonia solanacearum (Pseudomonas solanacearum) (381 aa). FASTA: opt: 1138 Z-score: 1260.3 E(): 2.6e-62 Smith-Waterman score: 1138; 45.722 identity in 374 aa overlap.; ABC transporter membrane protein	752001..753119	Francisella tularensis subsp. tularensis FSC198	4200706
YP_666875.1	CDS	isftu2	NC_008245.1	753217	753960	D	ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa).; transposase	753217..753960	Francisella tularensis subsp. tularensis FSC198	4199290
YP_666876.1	CDS	FTF0731c	NC_008245.1	754200	754646	R	ORF ftt0731c; hypothetical protein	complement(754200..754646)	Francisella tularensis subsp. tularensis FSC198	4199051
YP_666877.1	CDS	FTF0732	NC_008245.1	754743	755090	D	ORF ftt0732; hypothetical protein	754743..755090	Francisella tularensis subsp. tularensis FSC198	4199052
YP_666878.1	CDS	FTF0733	NC_008245.1	755119	755589	D	Similar to Q9A7J3 Glutathione peroxidase from Caulobacter crescentus (160 aa). FASTA: opt: 605 Z-score: 801.1 E(): 9.9e-37 Smith-Waterman score: 605; 55.696 identity in 158 aa overlap. ORF ftt0733; glutathione peroxidase	755119..755589	Francisella tularensis subsp. tularensis FSC198	4199053
YP_666879.1	CDS	FTF0736	NC_008245.1	757877	758524	D	Similar to Q8REM4 Hypothetical protein FN1075 (215 aa). FASTA: opt: 221 Z-score: 288.5 E(): 3.5e-08 Smith-Waterman score: 221; 25.463identity in 216 aa overlap. ORF ftt0736; hypothetical protein	757877..758524	Francisella tularensis subsp. tularensis FSC198	4199171
YP_666880.1	CDS	FTF0737c	NC_008245.1	758535	758663	R	ORF ftt0737c; hypothetical protein	complement(758535..758663)	Francisella tularensis subsp. tularensis FSC198	4199172
YP_666881.1	CDS	yjeF	NC_008245.1	758831	760375	D	Similar to Q82Y67 Possible sugar kinase from Nitrosomonas europaea (505 aa). FASTA: Z-score: 922.3 E(): 1.8e-43 Smith-Waterman score: 856; 35.529 identity in 501 aa overlap.; carbohydrate kinase family protein (YjeF-related protein)	758831..760375	Francisella tularensis subsp. tularensis FSC198	4199113
YP_666882.1	CDS	hslR	NC_008245.1	760359	760727	R	Similar to Q88AZ6 Heat shock protein 15 from Pseudomonas syringae (pv. tomato) (135 aa). FASTA: Z-score: 549.3 E(): 1.1e-22 Smith-Waterman score: 447; 58.824 identity in 119 aa overlap.; heat shock protein 15 (HSP15)	complement(760359..760727)	Francisella tularensis subsp. tularensis FSC198	4200207
YP_666883.1	CDS	ostA2	NC_008245.1	761131	763296	R	Similar to OSTA_XYLFT (Q87AI9) Organic solvent tolerance protein from Xylella fastidiosa (strain Temecula1 / ATCC 700964) (792 aa). FASTA: opt: 653 Z-score: 763.8 E(): 1.2e-34 Smith-Waterman score: 678; 24.212 identity in 698 aa overlap.; organic solvent tolerance protein	complement(761131..763296)	Francisella tularensis subsp. tularensis FSC198	4200088
YP_666884.1	CDS	FTF0741c	NC_008245.1	763318	763548	R	ORF ftt0741c; hypothetical protein	complement(763318..763548)	Francisella tularensis subsp. tularensis FSC198	4199173
YP_666885.1	CDS	FTF0742	NC_008245.1	763856	765844	D	ORF ftt0742; lipoprotein	763856..765844	Francisella tularensis subsp. tularensis FSC198	4199174
YP_666886.1	CDS	FTF0743	NC_008245.1	766525	767340	D	Similar to Q87Q96 Conserved hypothetical protein from Vibrio parahaemolyticus (274 aa). FASTA: opt: 950 Z-score: 1132.9 E(): 3.3e-55 Smith-Waterman score: 950; 49.259 identity in 270 aa overlap. ORF ftt0743; hypothetical protein	766525..767340	Francisella tularensis subsp. tularensis FSC198	4199175
YP_666887.1	CDS	FTF0744c	NC_008245.1	767439	767858	R	ORF ftt0744c; hypothetical protein	complement(767439..767858)	Francisella tularensis subsp. tularensis FSC198	4199176
YP_666888.1	CDS	FTF0745c	NC_008245.1	767880	768236	R	ORF ftt0745c; hypothetical protein	complement(767880..768236)	Francisella tularensis subsp. tularensis FSC198	4199177
YP_666889.1	CDS	FTF0746c	NC_008245.1	768334	769125	R	Similar to Q88NQ5 Membrane protein, putative from Pseudomonas putida (strain KT2440) (662 aa). FASTA: opt: 267 Z-score: 319.4 E(): 6.8e-10 Smith-Waterman score: 269; 27.179 identity in 195 aa overlap. ORF ftt0746c; hypothetical protein	complement(768334..769125)	Francisella tularensis subsp. tularensis FSC198	4199178
YP_666890.1	CDS	FTF0747c	NC_008245.1	769115	769900	R	Similar to Q88NQ3 Membrane fusion protein,putative (289 aa). FASTA: opt: 721 Z-score: 853.4 E(): 1.2e-39 Smith-Waterman score: 721; 41.434identity in 251 aa overlap. Similar to ydhJ and yhcQ in E. coli. ORF ftt0747c; hypothetical protein	complement(769115..769900)	Francisella tularensis subsp. tularensis FSC198	4199179
YP_666891.1	CDS	FTF0748	NC_008245.1	770280	770999	D	Similar to Q93PU6 Putative regulatory protein TtgV from Pseudomonas putida (259 aa). FASTA: opt: 485 Z-score: 588.0 E(): 7.4e-25 Smith-Waterman score: 485; 33.473 identity in 239 aa overlap. ORF ftt0748; hypothetical protein	770280..770999	Francisella tularensis subsp. tularensis FSC198	4199180
YP_666892.1	CDS	FTF0749c	NC_008245.1	771059	772045	R	Aa 8-183 identical to AAP97845 Hypothetical protein (Fragment) from Francisella tularensis ssp. tularensis strain SchuS4 (176 aa). Similar to Q8CL71 Hypothetical from Yersinia pestis (311 aa). FASTA: opt: 842 Z-score: 992.9 E(): 2e-47 Smith-Waterman score: 842; 44.710 identity in 293 aa overlap ORF ftt0749c; hypothetical protein	complement(771059..772045)	Francisella tularensis subsp. tularensis FSC198	4199181
YP_666893.1	CDS	FTF0750	NC_008245.1	772251	773237	D	Similar to Q83AM1 Radical SAM domain protein from Coxiella burnetii (342 aa). FASTA: opt: 1094 Z-score: 1304.2 E(): 9.4e-65 Smith-Waterman score: 1094; 48.930 identity in 327 aa overlap. ORF ftt0750; hypothetical protein	772251..773237	Francisella tularensis subsp. tularensis FSC198	4199182
YP_666894.1	CDS	cspA	NC_008245.1	773308	773511	R	Similar to Q89UH2 Cold shock protein from Bradyrhizobium japonicum (70 aa). FASTA: opt: 297 Z-score: 443.7 E(): 8e-17 Smith-Waterman score: 297; 66.176 identity in 68 aa overlap.; cold shock protein	complement(773308..773511)	Francisella tularensis subsp. tularensis FSC198	4200279
YP_666895.1	CDS	FTF0752c	NC_008245.1	773710	773907	R	ORF ftt0752c; hypothetical protein	complement(773710..773907)	Francisella tularensis subsp. tularensis FSC198	4199183
YP_666896.1	CDS	rpsU	NC_008245.1	774283	774483	D	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21	774283..774483	Francisella tularensis subsp. tularensis FSC198	4198960
YP_666897.1	CDS	FTF0754c	NC_008245.1	774541	774720	R	ORF ftt0754c; hypothetical protein	complement(774541..774720)	Francisella tularensis subsp. tularensis FSC198	4199184
YP_666898.1	CDS	FTF0755	NC_008245.1	775136	775630	D	ORF ftt0755; hypothetical protein	775136..775630	Francisella tularensis subsp. tularensis FSC198	4199185
YP_666899.1	CDS	FTF0756	NC_008245.1	775721	776860	D	Similar to Q83BX5 Cation-efflux family protein from Coxiella burnetii (378 aa). FASTA: opt: 773 Z-score: 908.9 E(): 9.8e-43 Smith-Waterman score: 774; 34.605 identity in 367 aa overlap. ORF ftt0756; cation-efflux family protein	775721..776860	Francisella tularensis subsp. tularensis FSC198	4199186
YP_666900.1	CDS	galU	NC_008245.1	776877	777740	D	Similar to Q9K0G7 UTP--glucose-1-phosphate uridylyltransferase from Neisseria meningitidis (serogroup B) (289 aa). FASTA: opt: 1017 Z-score: 1291.1 E(): 5e-64 Smith-Waterman score: 1017; 57.439 identity in 289 aa overlap.; UTP--glucose-1-phosphate uridylyltransferase	776877..777740	Francisella tularensis subsp. tularensis FSC198	4199271
YP_666901.1	CDS	FTF0759	NC_008245.1	779213	780130	D	Similar to YYAM_BACSU (P37511) Hypothetical transport protein yyaM from Bacillus subtilis (305 aa). FASTA: opt: 402 Z-score: 452.6 E(): 2.6e-17 Smith-Waterman score: 402; 25.614 identity in 285 aa overlap. ORF ftt0759; hypothetical protein	779213..780130	Francisella tularensis subsp. tularensis FSC198	4199187
YP_666902.1	CDS	FTF0760c	NC_008245.1	780133	780339	R	ORF ftt0760c; lipoprotein	complement(780133..780339)	Francisella tularensis subsp. tularensis FSC198	4199188
YP_666903.1	CDS	FTF0761c	NC_008245.1	780424	780717	R	ORF ftt0761c; hypothetical protein	complement(780424..780717)	Francisella tularensis subsp. tularensis FSC198	4199189
YP_666904.1	CDS	recF	NC_008245.1	780739	781788	R	Similar to RECF_PROMI (P22839) DNA replication and repair protein from Proteus mirabilis (362 aa). FASTA: opt: 874 Z-score: 1010.7 E(): 2.1e-48 Smith-Waterman score: 874; 37.394 identity in 353 aa overlap.; DNA replication and repair protein RecF	complement(780739..781788)	Francisella tularensis subsp. tularensis FSC198	4200603
YP_666905.1	CDS	yjjV	NC_008245.1	781792	782538	R	Similar to YJJV_ECOLI (P39408) Putative deoxyribonuclease yjjV (259 aa). FASTA: opt: 503 Z-score: 595.3 E(): 2.9e-25 Smith-Waterman score: 503; 31.048 identity in 248 aa overlap.; TatD related DNAse family protein	complement(781792..782538)	Francisella tularensis subsp. tularensis FSC198	4199032
YP_666906.1	CDS	glyS	NC_008245.1	782731	784815	D	Similar to SYGB_COXBU (P45651) Glycyl-tRNA synthetase beta chain from Coxiella burnetii (689 aa). FASTA: opt: 1810 Z-score: 2108.8 E(): 1.4e-109 Smith-Waterman score: 1810; 42.939 identity in 694 aa overlap.; glycyl-tRNA synthetase subunit beta	782731..784815	Francisella tularensis subsp. tularensis FSC198	4200290
YP_666907.1	CDS	isftu1	NC_008245.1	784955	785739	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(784955..785281,785281..785739)	Francisella tularensis subsp. tularensis FSC198	4199634
YP_666908.1	CDS	deoD	NC_008245.1	785908	786630	D	Similar to Q9PQL0 Purine-nucleoside phosphorylase from Ureaplasma parvum (Ureaplasma urealyticum biotype 1) (239 aa). FASTA: opt: 697 Z-score: 837.2 E(): 9.7e-39 Smith-Waterman score: 697; 47.534 identity in 223 aa overlap.; purine nucleoside phosphorylase	785908..786630	Francisella tularensis subsp. tularensis FSC198	4199346
YP_666909.1	CDS	FTF0767c	NC_008245.1	786627	787076	R	ORF ftt0767c; hypothetical protein	complement(786627..787076)	Francisella tularensis subsp. tularensis FSC198	4199912
YP_666910.1	CDS	FTF0768c	NC_008245.1	787080	788108	R	ORF ftt0768c; hypothetical protein	complement(787080..788108)	Francisella tularensis subsp. tularensis FSC198	4199913
YP_666911.1	CDS	secA	NC_008245.1	788240	790960	D	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA	788240..790960	Francisella tularensis subsp. tularensis FSC198	4200733
YP_666912.1	CDS	rplU	NC_008245.1	793029	793343	D	Similar to AAP95195 50S ribosomal protein L21 from Haemophilus ducreyi (103 aa). FASTA: opt: 435 Z-score: 570.3 E(): 7.1e-24 Smith-Waterman score: 435; 66.019 identity in 103 aa overlap.; 50S ribosomal protein L21	793029..793343	Francisella tularensis subsp. tularensis FSC198	4198997
YP_666913.1	CDS	rpmA	NC_008245.1	793374	793628	D	involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27	793374..793628	Francisella tularensis subsp. tularensis FSC198	4199002
YP_666914.1	CDS	FTF0774	NC_008245.1	794015	794392	D	Similar to Q8DJY4 Tll1086 protein from Synechococcus elongatus (Thermosynechococcus elongatus) (126 aa). FASTA: opt: 516 Z-score: 715.9 E(): 5.5e-32 Smith-Waterman score: 516; 64.348 identity in 115 aa overlap. ORF ftt0774; hypothetical protein	794015..794392	Francisella tularensis subsp. tularensis FSC198	4199914
YP_666915.1	CDS	rnd	NC_008245.1	795628	796722	R	Similar to Q8YGF6 Ribonuclease D from Brucella melitensis (385 aa). FASTA: opt: 538 Z-score: 584.5 E(): 1.2e-24 Smith-Waterman score: 538; 28.919 identity in 370 aa overlap.; ribonuclease D	complement(795628..796722)	Francisella tularensis subsp. tularensis FSC198	4199226
YP_666916.1	CDS	uvrC	NC_008245.1	796831	798669	D	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C	796831..798669	Francisella tularensis subsp. tularensis FSC198	4200135
YP_666917.1	CDS	FTF0778	NC_008245.1	798736	799110	D	ORF ftt0778; hypothetical protein	798736..799110	Francisella tularensis subsp. tularensis FSC198	4199915
YP_666918.1	CDS	isftu1	NC_008245.1	799188	799972	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(799188..799514,799514..799972)	Francisella tularensis subsp. tularensis FSC198	4199635
YP_666919.1	CDS	FTF0780c	NC_008245.1	800248	800517	R	ORF ftt0780c; hypothetical protein	complement(800248..800517)	Francisella tularensis subsp. tularensis FSC198	4199916
YP_666920.1	CDS	FTF0781c	NC_008245.1	800507	801220	R	Similar to Q82UL5 Hypothetical protein from Nitrosomonas europaea (239 aa). FASTA: opt: 736 Z-score: 920.8 E(): 2.1e-43 Smith-Waterman score: 736; 54.680 identity in 203 aa overlap. The family of possible lysine decarboxylase proteins shares a highly conserved motif PGGXGTXXE that is probably functionally important. This protein has that motif. ORF ftt0781c; hypothetical protein	complement(800507..801220)	Francisella tularensis subsp. tularensis FSC198	4199917
YP_666921.1	CDS	fabI	NC_008245.1	801506	802288	D	Similar to Q87YS1 Enoyl-(acyl-carrier-protein) reductase from Pseudomonas syringae (pv. tomato) (264 aa). FASTA: opt: 1071 Z-score: 1313.1 E(): 3e-65 Smith-Waterman score: 1071; 62.595 identity in 262 aa overlap.; enoyl-[acyl-carrier-protein] reductase (NADH)	801506..802288	Francisella tularensis subsp. tularensis FSC198	4199682
YP_666922.1	CDS	ars	NC_008245.1	802435	803397	D	Similar to Q9CPJ8 Arylsulfatase from Pasteurella multocida (327 aa). FASTA: opt: 544 Z-score: 669.4 E(): 2.2e-29 Smith-Waterman score: 544; 31.420 identity in 331 aa overlap.; arylsulfatase	802435..803397	Francisella tularensis subsp. tularensis FSC198	4199685
YP_666923.1	CDS	FTF0784	NC_008245.1	803409	803738	D	ORF ftt0784; hypothetical protein	803409..803738	Francisella tularensis subsp. tularensis FSC198	4199918
YP_666924.1	CDS	FTF0785	NC_008245.1	803726	804547	D	Similar to Q88K93 Conserved hypothetical protein (277 aa). FASTA: opt: 718 Z-score: 855.8 E(): 8.9e-40 Smith-Waterman score: 718; 42.308identity in 260 aa overlap. ORF ftt0785; hypothetical protein	803726..804547	Francisella tularensis subsp. tularensis FSC198	4199919
YP_666925.1	CDS	FTF0786	NC_008245.1	804544	805242	D	ORF ftt0786; hypothetical protein	804544..805242	Francisella tularensis subsp. tularensis FSC198	4199920
YP_666926.1	CDS	FTF0787	NC_008245.1	805253	805843	D	Similar to Q8EDN3 Conserved hypothetical protein from Shewanella oneidensis (197 aa). FASTA: opt: 435 Z-score: 540.9 E(): 3.1e-22 Smith-Waterman score: 435; 42.935 identity in 184 aa overlap. ORF ftt0787; DoxD-like family protein	805253..805843	Francisella tularensis subsp. tularensis FSC198	4199921
YP_666927.1	CDS	kdsD	NC_008245.1	805847	806830	R	Similar to Q8KLW6 Hypothetical protein from Pseudomonas stutzeri (Pseudomonas perfectomarina) (324 aa). FASTA: opt: 1095 Z-score: 1307.1 E(): 6.5e-65 Smith-Waterman score: 1095; 54.489 identity in 323 aa overlap. Homologs are involved in sialic acid capsule biosynthesis in some pathogenic strains of Escherichia coli.; arabinose phosphate isomerase	complement(805847..806830)	Francisella tularensis subsp. tularensis FSC198	4199508
YP_666928.1	CDS	rpe	NC_008245.1	806955	807623	D	Similar to Q8EK14 Ribulose-phosphate 3-epimerase (225 aa). FASTA: opt: 953 Z-score: 1164.4 E(): 5.8e-57 Smith-Waterman score: 953; 65.766identity in 222 aa overlap.; D-ribulose-phosphate 3-epimerase	806955..807623	Francisella tularensis subsp. tularensis FSC198	4200770
YP_666929.1	CDS	FTF0790	NC_008245.1	807604	808998	D	Similar to Q9FDJ5 Putative glycosyltransferase from Lactobacillus rhamnosus (466 aa). FASTA: opt: 733 Z-score: 876.0 E(): 6.7e-41 Smith-Waterman score: 733; 33.333 identity in 399 aa overlap. ORF ftt0790; sugar transferase	807604..808998	Francisella tularensis subsp. tularensis FSC198	4199922
YP_666930.1	CDS	galE	NC_008245.1	808991	810010	D	UDP-glucose 4-epimerase	808991..810010	Francisella tularensis subsp. tularensis FSC198	4199208
YP_666931.1	CDS	FTF0792	NC_008245.1	810014	811243	D	Similar to Q9HTC0 Glycosyltransferase WbpZ from Pseudomonas aeruginosa (381 aa). FASTA: opt: 621 Z-score: 721.7 E(): 2.6e-32 Smith-Waterman score: 1019; 38.725 identity in 408 aa overlap. ORF ftt0792; glycosyl transferases group 1 family protein	810014..811243	Francisella tularensis subsp. tularensis FSC198	4199923
YP_666932.1	CDS	FTF0793	NC_008245.1	811240	812922	D	Similar to Q8DMA7 ATP-binding protein of ABC transporter from Synechococcus elongatus (Thermosynechococcus elongatus) (610 aa). FASTA: opt: 1084 Z-score: 1105.1 E(): 1.2e-53 Smith-Waterman score: 1084; 35.159 identity in 566 aa overlap. ORF ftt0793; ABC transporter ATP-binding and membrane protein	811240..812922	Francisella tularensis subsp. tularensis FSC198	4199924
YP_666933.1	CDS	FTF0794	NC_008245.1	812936	814222	D	Similar to AAP76675 Phosphoserine phosphatase (EC 3.1.3.3) from Helicobacter hepaticus (199 aa). FASTA: opt: 751 Z-score: 908.2 E(): 1.1e-42 Smith-Waterman score: 751; 55.385 identity in 195 aa overlap (18-212:4-198) AND to AAP76674 Hypothetical protein from Helicobacter hepaticus (213 aa). FASTA: opt: 823 Z-score: 994.3 E(): 1.7e-47 Smith-Waterman score: 823; 57.212 identity in 208 aa overlap (221-428:6-213). Seems to be two genes in some organisms. ORF ftt0794; hypothetical protein	812936..814222	Francisella tularensis subsp. tularensis FSC198	4199925
YP_666934.1	CDS	FTF0795	NC_008245.1	814161	814844	D	Similar to AAP76671 Hypothetical protein cfa from Helicobacter hepaticus (210 aa). FASTA: opt: 627 Z-score: 745.4 E(): 1.3e-33 Smith-Waterman score: 627; 44.660 identity in 206 aa overlap. ORF ftt0795; hypothetical protein	814161..814844	Francisella tularensis subsp. tularensis FSC198	4199926
YP_666935.1	CDS	FTF0796	NC_008245.1	814848	815609	D	ORF ftt0796; hypothetical protein	814848..815609	Francisella tularensis subsp. tularensis FSC198	4199927
YP_666936.1	CDS	FTF0797	NC_008245.1	815618	816577	D	Similar to O85000 Galactosyl transferase from Streptococcus pneumoniae (323 aa). FASTA: opt: 577 Z-score: 682.7 E(): 3.9e-30 Smith-Waterman score: 577; 40.171 identity in 234 aa overlap. Same homolog as for next downstream ORF. ORF ftt0797; glycosyl transferase family protein	815618..816577	Francisella tularensis subsp. tularensis FSC198	4199928
YP_666937.1	CDS	FTF0798	NC_008245.1	816594	817601	D	Similar to O85000 Galactosyl transferase from Streptococcus pneumoniae (323 aa). FASTA: opt: 499 Z-score: 609.1 E(): 4.9e-26 Smith-Waterman score: 499; 34.454 identity in 238 aa overlap. Same homolog as for next upstream ORF. ORF ftt0798; glycosyl transferase family protein	816594..817601	Francisella tularensis subsp. tularensis FSC198	4199929
YP_666938.1	CDS	FTF0799	NC_008245.1	817604	818617	D	Similar to Q00481 Second mannosyl transferase from Salmonella enterica (336 aa). FASTA: opt: 651 Z-score: 775.2 E(): 2.7e-35 Smith-Waterman score: 651; 35.455 identity in 330 aa overlap. ORF ftt0799; glycosyl transferases group 1 family protein	817604..818617	Francisella tularensis subsp. tularensis FSC198	4199930
YP_666939.1	CDS	FTF0800	NC_008245.1	818636	819298	D	Similar to Q8FV27 Hydrolase, haloacid dehalogenase-like family from Brucella suis (234 aa). FASTA: opt: 422 Z-score: 503.3 E(): 3.8e-20 Smith-Waterman score: 422; 33.486identity in 218 aa overlap. ORF ftt0800; haloacid dehalogenase-like hydrolase family protein	818636..819298	Francisella tularensis subsp. tularensis FSC198	4199931
YP_666940.1	CDS	FTF0801c	NC_008245.1	819580	820686	R	Similar to Q9YG89 310AA long hypothetical sugar kinase from Aeropyrum pernix (310 aa). FASTA: opt: 245 Z-score: 292.6 E(): 2.1e-08 Smith-Waterman score: 311; 25.795 identity in 283 aa overlap. ORF ftt0801c; carbohydrate/purine kinase pfkB family protein	complement(819580..820686)	Francisella tularensis subsp. tularensis FSC198	4199969
YP_666941.1	CDS	cphB	NC_008245.1	820889	821707	D	Similar to CPHB_SYNY8 (P56946) Cyanophycinase from Synechocystis sp. (strain PCC 6308) (272 aa). FASTA: opt: 701 Z-score: 857.3 E(): 7.4e-40 Smith-Waterman score: 701; 41.667 identity in 264 aa overlap.; cyanophycinase	820889..821707	Francisella tularensis subsp. tularensis FSC198	4200274
YP_666942.1	CDS	ans	NC_008245.1	821923	822786	D	Similar to Q9ABX3 Asparaginase family protein from Caulobacter crescentus (292 aa). FASTA: 146 opt: 465 Z-score: 567.7 E(): 1e-23 Smith-Waterman score: 465; 35.606 identity in 264 aa overlap.; asparaginase	821923..822786	Francisella tularensis subsp. tularensis FSC198	4199423
YP_666943.1	CDS	FTF0804	NC_008245.1	823458	824714	D	Similar to O54543 (O54543) CITA from Legionella pneumophila (418 aa). FASTA: opt: 905 Z-score: 915.1 E(): 4.5e-43 Smith-Waterman score: 905; 33.254 identity in 418 aa overlap. ORF ftt0804; major facilitator transporter	823458..824714	Francisella tularensis subsp. tularensis FSC198	4199970
YP_666944.1	CDS	capB	NC_008245.1	824790	826007	D	Similar to CAD71904 Capsule biosynthesis protein CapB from Rhodopirellula baltica (441 aa). FASTA: opt: 1155 Z-score: 1414.5 E(): 6.8e-71 Smith-Waterman score: 1156; 46.763 identity (50.914 ungapped) in 417 aa overlap.; capsule biosynthesis protein capB	824790..826007	Francisella tularensis subsp. tularensis FSC198	4200313
YP_666945.1	CDS	capC	NC_008245.1	826032	826496	D	Similar to Q8REZ4 CapC protein from Fusobacterium nucleatum (152 aa). FASTA: opt: 360 Z-score: 420.9 E(): 1.5e-15 Smith-Waterman score: 360; 35.616 identity in 146 aa overlap.; capsule biosynthesis protein CapC	826032..826496	Francisella tularensis subsp. tularensis FSC198	4200314
YP_666946.1	CDS	FTF0807	NC_008245.1	826498	827709	D	Similar to CAD71902 Hypothetical protein from Rhodopirellula baltica (404 aa). FASTA: opt: 477 Z-score: 563.9 E(): 1.6e-23 Smith-Waterman score: 553; 31.633 identity in 392 aa overlap. ORF ftt0807; hypothetical protein	826498..827709	Francisella tularensis subsp. tularensis FSC198	4199971
YP_666947.1	CDS	spoT	NC_008245.1	827769	829892	D	Similar to SPOT_ECOLI Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase from Escherichia coli (702 aa). FASTA: opt: 1849 Z-score: 2107.7 E(): 1.7e-109 Smith-Waterman score: 1849; 41.210 identity in 711 aa overlap.; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase/(p)ppGpp synthase	827769..829892	Francisella tularensis subsp. tularensis FSC198	4199083
YP_666948.1	CDS	recR	NC_008245.1	829900	830502	R	involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR	complement(829900..830502)	Francisella tularensis subsp. tularensis FSC198	4200607
YP_666949.1	CDS	ybaB	NC_008245.1	830502	830840	R	Similar to YBAB_ECOLI Hypothetical UPF0133 protein ybaB from Escherichia coli (109 aa). FASTA: opt: 332 Z-score: 403.8 E(): 1.3e-14 Smith-Waterman score: 332; 49.074identity in 108 aa overlap.; hypothetical protein	complement(830502..830840)	Francisella tularensis subsp. tularensis FSC198	4200701
YP_666950.1	CDS	murG	NC_008245.1	830850	831965	R	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase	complement(830850..831965)	Francisella tularensis subsp. tularensis FSC198	4200110
YP_666951.1	CDS	gcvH2	NC_008245.1	832069	832449	D	Similar to GCS1_SULTO Probable glycine cleavage system H from Sulfolobus tokodaii (142 aa). FASTA: opt: 397 Z-score: 525.8 E(): 2.1e-21 Smith-Waterman score: 397; 43.089 identity in 123 aa overlap.; glycine cleavage system protein H	832069..832449	Francisella tularensis subsp. tularensis FSC198	4199278
YP_666952.1	CDS	FTF0813	NC_008245.1	832439	832735	D	ORF ftt0813; hypothetical protein	832439..832735	Francisella tularensis subsp. tularensis FSC198	4199972
YP_666953.1	CDS	FTF0814c	NC_008245.1	832821	833420	R	ORF ftt0814c; hypothetical protein	complement(832821..833420)	Francisella tularensis subsp. tularensis FSC198	4199973
YP_666954.1	CDS	FTF0815c	NC_008245.1	833428	833676	R	ORF ftt0815c; hypothetical protein	complement(833428..833676)	Francisella tularensis subsp. tularensis FSC198	4199974
YP_666955.1	CDS	FTF0816c	NC_008245.1	833720	834613	R	Similar to Q8EHY2 Chitin-binding protein,putative from Shewanella oneidensis (491 aa). FASTA: opt: 532 Z-score: 628.3 E(): 4.2e-27 Smith-Waterman score: 532; 43.500 identity in 200 aa overlap. ORF ftt0816c; chitin binding protein	complement(833720..834613)	Francisella tularensis subsp. tularensis FSC198	4199975
YP_666956.1	CDS	thrS	NC_008245.1	835053	836957	D	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase	835053..836957	Francisella tularensis subsp. tularensis FSC198	4199143
YP_666957.1	CDS	infC	NC_008245.1	837033	837500	D	Similar to IF3_ECOLI Translation initiation factor IF-3 from Escherichia coli (180 aa). FASTA: opt: 674 Z-score: 836.1 E(): 1.1e-38 Smith-Waterman score: 674; 64.103 identity in 156 aa overlap.; translation initiation factor IF-3	837033..837500	Francisella tularensis subsp. tularensis FSC198	4199611
YP_666958.1	CDS	rpmI	NC_008245.1	837543	837740	D	Similar to RL35_ECOLI 50S ribosomal protein L35 from Escherichia coli (64 aa). FASTA: opt: 247 Z-score: 385.9 E(): 1.3e-13 Smith-Waterman score: 247; 62.500 identity in 64 aa overlap.; 50S ribosomal protein L35	837543..837740	Francisella tularensis subsp. tularensis FSC198	4200324
YP_666959.1	CDS	rplT	NC_008245.1	837776	838132	D	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20	837776..838132	Francisella tularensis subsp. tularensis FSC198	4198996
YP_666960.1	CDS	FTF0821	NC_008245.1	838174	838878	D	Similar to Q9KRB9 Hypothetical protein VC1723 from Vibrio cholerae (229 aa). FASTA: opt: 344 Z-score: 394.7 E(): 4.3e-14 Smith-Waterman score: 344; 29.075 identity in 227 aa overlap. ORF ftt0821; hypothetical protein	838174..838878	Francisella tularensis subsp. tularensis FSC198	4199976
YP_666961.1	CDS	isftu1	NC_008245.1	839170	839954	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(839170..839496,839496..839954)	Francisella tularensis subsp. tularensis FSC198	4199636
YP_666962.1	CDS	FTF0823	NC_008245.1	840178	840825	D	Similar to Q9K8B7 Mutator MutT protein from Bacillus halodurans (207 aa). FASTA: opt: 413 Z-score: 505.4 E(): 2.9e-20 Smith-Waterman score: 413; 36.649identity in 191 aa overlap. ORF ftt0823; MutT protein	840178..840825	Francisella tularensis subsp. tularensis FSC198	4199977
YP_666963.1	CDS	arsC1	NC_008245.1	840843	841196	D	Similar to Q8CPW9 Arsenate reductase from Staphylococcus epidermidis (117 aa). FASTA: opt: 276 Z-score: 376.2 E(): 4.6e-13 Smith-Waterman score: 276; 32.759 identity in 116 aa overlap.; arsenate reductase	840843..841196	Francisella tularensis subsp. tularensis FSC198	4199686
YP_666964.1	CDS	FTF0825c	NC_008245.1	841220	841555	R	hypothetical lipoprotein, no significant homologs. ORF ftt0825c; hypothetical protein	complement(841220..841555)	Francisella tularensis subsp. tularensis FSC198	4199978
YP_666965.1	CDS	FTF0826c	NC_008245.1	841732	841977	R	ORF ftt0826c; lipoprotein	complement(841732..841977)	Francisella tularensis subsp. tularensis FSC198	4199979
YP_666966.1	CDS	FTF0827c	NC_008245.1	842055	843368	R	Similar to YIEG_ECOLI Hypothetical protein yieG from Escherichia coli (445 aa). FASTA: opt: 945 Z-score: 1037.7 E(): 6.6e-50 Smith-Waterman score: 945; 34.633 identity in 436 aa overlap. ORF ftt0827c; hypothetical protein	complement(842055..843368)	Francisella tularensis subsp. tularensis FSC198	4199980
YP_666967.1	CDS	FTF0829c	NC_008245.1	845033	846748	R	Similar to Q845W9 Aspartate:alanine antiporter from Pseudomonas dacunhae (561 aa). FASTA: opt: 1359 Z-score: 1502.2 bits: 287.8 E(): 8.8e-76 Smith-Waterman score: 1359; 38.351 identity in 558 aa overlap. ORF ftt0829c; aspartate:alanine antiporter	complement(845033..846748)	Francisella tularensis subsp. tularensis FSC198	4199982
YP_666968.1	CDS	FTF0831c	NC_008245.1	847903	849156	R	Weakly similar to Q8A8H3 Outer membrane protein,OmpA family from Bacteroides thetaiotaomicron (266 aa). FASTA: opt: 184 Z-score: 220.7 E(): 0.00021 Smith-Waterman score: 184; 29.299 identity in 157 aa overlap. ORF ftt0831c; OmpA family protein	complement(847903..849156)	Francisella tularensis subsp. tularensis FSC198	4199984
YP_666969.1	CDS	fkpB	NC_008245.1	849348	849812	D	Similar to FKBX_ECOLI (P22563) FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase from Escherichia coli (148 aa). FASTA: opt: 357 Z-score: 475.0 E(): 1.4e-18 Smith-Waterman score: 357; 38.129 identity in 139 aa overlap.; FKBP-type 16 kDa peptidyl-prolyl cis-transisomerase	849348..849812	Francisella tularensis subsp. tularensis FSC198	4199411
YP_666970.1	CDS	ispH	NC_008245.1	849793	850749	D	catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase	849793..850749	Francisella tularensis subsp. tularensis FSC198	4199304
YP_666971.1	CDS	aroQ	NC_008245.1	850751	851113	D	Similar to CHMU_BACSU Chorismate mutase from Bacillus subtilis (127 aa). FASTA: opt: 360 Z-score: 492.8 E(): 1.5e-19 Smith-Waterman score: 360; 48.305identity in 118 aa overlap.; chorismate mutase	850751..851113	Francisella tularensis subsp. tularensis FSC198	4199439
YP_666972.1	CDS	FTF0835	NC_008245.1	851122	851943	D	Similar to Q8EBE8 CDP-diacylglycerol--serine O-phosphatidyltransferase from Shewanella oneidensis (269 aa). FASTA: opt: 456 Z-score: 550.1 E(): 9.5e-23 Smith-Waterman score: 564; 37.209 identity in 258 aa overlap. ORF ftt0835; CDP-alcohol phosphatidyltransferase	851122..851943	Francisella tularensis subsp. tularensis FSC198	4199985
YP_666973.1	CDS	FTF0836c	NC_008245.1	851948	852172	R	ORF ftt0836c; hypothetical protein	complement(851948..852172)	Francisella tularensis subsp. tularensis FSC198	4199986
YP_666974.1	CDS	tolQ	NC_008245.1	852313	853032	D	Similar to TOLQ_ECOLI TolQ protein from Escherichia coli (230 aa). FASTA: opt: 568 Z-score: 690.3 E(): 1.5e-30 Smith-Waterman score: 568; 38.991 identity in 218 aa overlap.; TolQ protein	852313..853032	Francisella tularensis subsp. tularensis FSC198	4199151
YP_666975.1	CDS	tolR	NC_008245.1	853042	853488	D	Similar to TOLR_ECOLI TolR protein from Escherichia coli (142 aa). FASTA: opt: 303 Z-score: 379.2 bits: 76.1 E(): 3.2e-13 Smith-Waterman score: 303; 39.259identity in 135 aa overlap.; TolR protein	853042..853488	Francisella tularensis subsp. tularensis FSC198	4199857
YP_666976.1	CDS	tolA	NC_008245.1	853475	854386	D	FTF0839 Contains similarity to Pfam domain PF06519 (TolA protein), Score=-66.2, E-value=1.4e-05; tolA protein	853475..854386	Francisella tularensis subsp. tularensis FSC198	4199148
YP_666977.1	CDS	tolB	NC_008245.1	854386	855705	D	Similar to TOLB_ECOLI TolB protein precursor from Eschericia coli (430 aa). FASTA: opt: 692 Z-score: 785.2 E(): 7.6e-36 Smith-Waterman score: 717; 31.685identity in 445 aa overlap. TolB appears more highly conserved in other species: potential paralog; TolB protein precursor	854386..855705	Francisella tularensis subsp. tularensis FSC198	4199149
YP_666978.1	CDS	FTF0841	NC_008245.1	855709	855960	D	ORF ftt0841; lipoprotein	855709..855960	Francisella tularensis subsp. tularensis FSC198	4199987
YP_666979.1	CDS	FTF0842	NC_008245.1	855979	856602	D	Similar to PAL_ECOLI Peptidoglycan-associated lipoprotein from Escherichia coli (173 aa). FASTA: opt: 306 Z-score: 383.2 E(): 1.9e-13 Smith-Waterman score: 306; 33.333 identity in 162 aa overlap. ORF ftt0842; peptidoglycan-associated lipoprotein	855979..856602	Francisella tularensis subsp. tularensis FSC198	4200006
YP_666980.1	CDS	FTF0845	NC_008245.1	858830	859105	D	Similar to Q9K315 Hypothetical protein VCA0343 OR VCA029 from Vibrio cholerae (83 aa). FASTA: opt: 250 Z-score: 356.2 E(): 6e-12 Smith-Waterman score: 250; 58.462 identity (58.4620ngapped) in 65 aa overlap. ORF ftt0845; hypothetical protein	858830..859105	Francisella tularensis subsp. tularensis FSC198	4200009
YP_666981.1	CDS	FTF0846	NC_008245.1	859086	860585	D	Similar to Q9KS67 Deoxyribodipyrimidine photolyase,putative from Vibrio cholerae (504 aa). FASTA: opt: 1071 Z-score: 1263.0 E(): 1.8e-62 Smith-Waterman score: 1097; 37.817 identity in 513 aa overlap. ORF ftt0846; deoxyribodipyrimidine photolyase	859086..860585	Francisella tularensis subsp. tularensis FSC198	4200010
YP_666982.1	CDS	FTF0847	NC_008245.1	860639	862114	D	Similar to Q8U6P2 Hypothetical protein Atu4765 (507 aa). FASTA: opt: 1800 Z-score: 2192.9 415.3 E(): 3e-114 Smith-Waterman score: 1800; 53.608identity in 485 aa overlap. ORF ftt0847; hypothetical protein	860639..862114	Francisella tularensis subsp. tularensis FSC198	4200011
YP_666983.1	CDS	FTF0848	NC_008245.1	862111	862248	D	Similar to Q8P3G1 Hypothetical protein XCC4110 from Xanthomonas campestris (51 aa). FASTA: opt: 243 Z-score: 366.5 E(): 1.6e-12 Smith-Waterman score: 243; 63.636 identity in 44 aa overlap ORF ftt0848; hypothetical protein	862111..862248	Francisella tularensis subsp. tularensis FSC198	4200012
YP_666984.1	CDS	FTF0849	NC_008245.1	862374	863303	D	Similar to Q81YH5 Bile acid transporter family protein from Bacillus anthracis (322 aa). FASTA: initn: 551 init1: 399 opt: 605 Z-score: 641.1 E(): 8.1e-28 Smith-Waterman score: 605; 32.432identity in 296 aa overlap. ORF ftt0849; bile acid symporter family protein	862374..863303	Francisella tularensis subsp. tularensis FSC198	4200013
YP_666985.1	CDS	FTF0850	NC_008245.1	863353	863976	D	Similar to Q930D7 Hypothetical protein RA0261 Rhizobium meliloti (222 aa). FASTA: opt: 521 Z-score: 614.9 E(): 2.3e-26 Smith-Waterman score: 521; 42.424 identity in 198 aa overlap. ORF ftt0850; hypothetical protein	863353..863976	Francisella tularensis subsp. tularensis FSC198	4200014
YP_666986.1	CDS	FTF0851	NC_008245.1	864000	864758	D	Similar to Q83C04 Membrane protein, putative from Coxiella burnetii (263 aa). FASTA: opt: 338 Z-score: 387.6 E(): 1.1e-13 Smith-Waterman score: 341; 28.625 identity in 269 aa overlap. ORF ftt0851; hypothetical protein	864000..864758	Francisella tularensis subsp. tularensis FSC198	4200015
YP_666987.1	CDS	FTF0853	NC_008245.1	866452	867690	D	Similar to Q8PY17 Arsenite permease from Methanosarcina mazei (420 aa). FASTA: opt: 1294 Z-score: 1359.3 E(): 8e-68 Smith-Waterman score: 1294; 49.144 identity in 409 aa overlap. ORF ftt0853; arsenite permease family protein	866452..867690	Francisella tularensis subsp. tularensis FSC198	4200017
YP_666988.1	CDS	FTF0854c	NC_008245.1	867669	868091	R	Similar to Q8EM34 Hypothetical conserved protein from Oceanobacillus iheyensis (123 aa). FASTA: opt: 271 Z-score: 341.6 E(): 3.9e-11 Smith-Waterman score: 271; 37.190 identity in 121 aa overlap. ORF ftt0854c; hypothetical protein	complement(867669..868091)	Francisella tularensis subsp. tularensis FSC198	4200018
YP_666989.1	CDS	FTF0855c	NC_008245.1	868111	868470	R	Weakly similar to Q9KR35 Hypothetical protein VC1812 from Vibrio cholerae (139 aa). FASTA: opt: 184 Z-score: 256.0 E(): 2.3e-06 Smith-Waterman score: 184; 29.245 identity in 106 aa overlap. ORF ftt0855c; hypothetical protein	complement(868111..868470)	Francisella tularensis subsp. tularensis FSC198	4200019
YP_666990.1	CDS	ubiA	NC_008245.1	868484	869338	R	UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase	complement(868484..869338)	Francisella tularensis subsp. tularensis FSC198	4198976
YP_666991.1	CDS	FTF0857c	NC_008245.1	869341	869847	R	Weakly similar to similar to Q83F94 Chorismate--pyruvate lyase, putative from Coxiella burnetii (185 aa). FASTA: opt: 178 Z-score: 231.0 E(): 5.6e-05 Smith-Waterman score: 178; 27.215identity in 158 aa overlap ORF ftt0857c; hypothetical protein	complement(869341..869847)	Francisella tularensis subsp. tularensis FSC198	4200020
YP_666992.1	CDS	rph	NC_008245.1	869946	870653	D	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH	869946..870653	Francisella tularensis subsp. tularensis FSC198	4200771
YP_666993.1	CDS	FTF0859c	NC_008245.1	870707	871030	R	ORF ftt0859c; hypothetical protein	complement(870707..871030)	Francisella tularensis subsp. tularensis FSC198	4200021
YP_666994.1	CDS	FTF0860c	NC_008245.1	871135	871386	R	ORF ftt0860c; hypothetical protein	complement(871135..871386)	Francisella tularensis subsp. tularensis FSC198	4200022
YP_666995.1	CDS	FTF0861c	NC_008245.1	871449	872042	R	Similar to FMA2_BACNO (P17824) Fimbrial protein precursor (Pilin) from Bacteroides nodosus (Dichelobacter nodosus) (160 aa). FASTA: opt: 169 Z-score: 222.1 E(): 0.00018 Smith-Waterman score: 169; 34.646 identity in 127 aa overlap The pili fiber building block protein has a highly distinct primary structure; a short positively charged leader sequence, and a highly conserved and highly hydrophobic amino-terminal domain which forms the core of the pilus fiber; A variety of studies suggest that the invariant glycine (G) at -1 is required for prepilin cleavage and assembly and that the glutamate (E) at + 5 is essential for assembly and efficient N-terminal methylation but not cleavage. The region near the carboxy terminus is often hydrophilic and is stabilized by one or two disulfide bridges that may be involved in recognition of receptors. The genes with these characteristics are usually termed pilA, pilE, pilV, pilW, pilX and FimU. (Mattick John S.. 'Type IV Pili and twitching motility'. Annu. Rev. Microbiol. 2002. 56:289-314.) This protein has all the characteristics described above, but shows a weak global homology. ORF ftt0861c; Type IV pili fiber building block protein	complement(871449..872042)	Francisella tularensis subsp. tularensis FSC198	4200023
YP_666996.1	CDS	htpX	NC_008245.1	872147	873220	R	putative metalloprotease; heat shock protein HtpX	complement(872147..873220)	Francisella tularensis subsp. tularensis FSC198	4200648
YP_666997.1	CDS	FTF0863c	NC_008245.1	873224	873799	R	Similar to Q83DZ3 LemA protein from Coxiella burnetii (192 aa) initn: 723 init1: 655 opt: 732 Z-score: 803.2 bits: 155.4 E(): 7.6e-37 Smith-Waterman score: 732; 60.417 identity in 192 aa overlap. ORF ftt0863c; LemA-like protein	complement(873224..873799)	Francisella tularensis subsp. tularensis FSC198	4200024
YP_666998.1	CDS	FTF0864c	NC_008245.1	873847	874743	R	Similar to Q87XZ5 Transcriptional regulator, LysR family, from Pseudomonas syringae (308 aa). FASTA: opt: 591 Z-score: 726.5 E(): 1.4e-32 Smith-Waterman score: 591; 34.948 identity in 289 aa overlap. ORF ftt0864c; LysR family transcriptional regulator	complement(873847..874743)	Francisella tularensis subsp. tularensis FSC198	4200025
YP_666999.1	CDS	isftu2	NC_008245.1	876718	877461	D	ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa).; transposase	876718..877461	Francisella tularensis subsp. tularensis FSC198	4199291
YP_667000.1	CDS	FTF0868c	NC_008245.1	878966	879331	R	Similar to Q9RA93 ArsR from Sinorhizobium sp. As4 (115 aa). FASTA: opt: 185 Z-score: 259.0 bits: 53.3 E(): 1.6e-06 Smith-Waterman score: 185; 27.184 identity in 103 aa overlap. ORF ftt0868c; arsenical restistance operon repressor	complement(878966..879331)	Francisella tularensis subsp. tularensis FSC198	4199594
YP_667001.1	CDS	FTF0869	NC_008245.1	879474	880127	D	ORF ftt0869; hypothetical protein	879474..880127	Francisella tularensis subsp. tularensis FSC198	4199595
YP_667002.1	CDS	FTF0870c	NC_008245.1	880139	880270	R	ORF ftt0870c; hypothetical protein	complement(880139..880270)	Francisella tularensis subsp. tularensis FSC198	4199596
YP_667003.1	CDS	gpsA	NC_008245.1	880447	881445	D	NAD(P)+; catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	880447..881445	Francisella tularensis subsp. tularensis FSC198	4200296
YP_667004.1	CDS	FTF0872c	NC_008245.1	881446	881982	R	ORF ftt0872c; hypothetical protein	complement(881446..881982)	Francisella tularensis subsp. tularensis FSC198	4199597
YP_667005.1	CDS	radA	NC_008245.1	881987	883357	R	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA	complement(881987..883357)	Francisella tularensis subsp. tularensis FSC198	4200595
YP_667006.1	CDS	FTF0874c	NC_008245.1	883365	884135	R	ORF ftt0874c; hypothetical protein	complement(883365..884135)	Francisella tularensis subsp. tularensis FSC198	4199598
YP_667007.1	CDS	FTF0875c	NC_008245.1	884132	884731	R	Similar to YOHD_ECOLI (P33366) Hypothetical protein yohD from Escherichia coli (192 aa). FASTA: opt: 311 Z-score: 379.7 bits: 77.1 E(): 2.9e-13 Smith-Waterman score: 311; 24.870 identity (25.806 ungapped) in 193 aa overlap. ORF ftt0875c; hypothetical protein	complement(884132..884731)	Francisella tularensis subsp. tularensis FSC198	4199599
YP_667008.1	CDS	aroC	NC_008245.1	884734	885792	R	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase	complement(884734..885792)	Francisella tularensis subsp. tularensis FSC198	4199433
YP_667009.1	CDS	FTF0877c	NC_008245.1	885957	886586	R	ORF ftt0877c; hypothetical protein	complement(885957..886586)	Francisella tularensis subsp. tularensis FSC198	4199600
YP_667010.1	CDS	msrB	NC_008245.1	886605	887117	R	this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B	complement(886605..887117)	Francisella tularensis subsp. tularensis FSC198	4200102
YP_667011.1	CDS	sodC	NC_008245.1	887278	887835	D	superoxide dismutase (Cu-Zn) precusor. Identical to SODC_FRATU from F. tularensis LVS.; superoxide dismuate (Cu-Zn) precusor	887278..887835	Francisella tularensis subsp. tularensis FSC198	4199078
YP_667012.1	CDS	FTF0881c	NC_008245.1	888603	889997	R	Similar to AAP09927 Arginine permease from Bacillus cereus (474 aa). FASTA: opt: 1041 Z-score: 1224.1 E(): 2.5e-60 Smith-Waterman score: 1041; 35.604 identity in 455 aa overlap. ORF ftt0881c; amino acid permease	complement(888603..889997)	Francisella tularensis subsp. tularensis FSC198	4199602
YP_667013.1	CDS	aspC1	NC_008245.1	891762	892952	R	catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase	complement(891762..892952)	Francisella tularensis subsp. tularensis FSC198	4199689
YP_667014.1	CDS	FTF0885	NC_008245.1	893241	894020	D	Similar to Q8D6R6 Predicted Co/Zn/Cd cation transporter from Vibrio vulnificus (297 aa). FASTA: opt: 344 Z-score: 414.1 E(): 3.3e-15 Smith-Waterman score: 344; 25.296 identity in 253 aa overlap. ORF ftt0885; cation transporter	893241..894020	Francisella tularensis subsp. tularensis FSC198	4199605
YP_667015.1	CDS	FTF0886	NC_008245.1	894126	895775	D	Similar to P52118 DNA repair protein recN (Recombination protein (554 aa) fasta scores; opt: 1371 Z-score: 1221.7 E(): 3.4e-60 Smith-Waterman score: 1371; 39.674 identity in 552 aa overlap. ORF ftt0886; DNA repair protein recN	894126..895775	Francisella tularensis subsp. tularensis FSC198	4199606
YP_667016.1	CDS	FTF0887c	NC_008245.1	896347	896721	R	ORF ftt0887c; hypothetical protein	complement(896347..896721)	Francisella tularensis subsp. tularensis FSC198	4199607
YP_667017.1	CDS	FTF0888c	NC_008245.1	896714	897310	R	Similar to Q59607 Pilin precursor from Neisseria gonorrhoeae (169 aa). FASTA: opt: 244 Z-score: 305.7 E(): 3.5e-09 Smith-Waterman score: 244; 30.435 identity in 138 aa overlap. The pili fiber building block protein has a highly distinct primary structure; a short positively charged leader sequence, and a highly conserved and highly hydrophobic amino-terminal domain which forms the core of the pilus fiber; A variety of studies suggest that the invariant glycine (G) at -1 is required for prepilin cleavage and assembly and that the glutamate (E) at + 5 is essential for assembly and efficient N-terminal methylation but not cleavage. The region near the carboxy terminus is often hydrophilic and is stabilized by one or two disulfide bridges that may be involved in recognition of receptors. The genes with these characteristics are usually termed pilA, pilE, pilV, pilW, pilX and FimU. (Mattick John S.. 'Type IV Pili and twitching motility'. Annu. Rev. Microbiol. 2002. 56:289-314.) This protein has all the characteristics described above. ORF ftt0888c; Type IV pili fiber building block protein	complement(896714..897310)	Francisella tularensis subsp. tularensis FSC198	4199608
YP_667018.1	CDS	FTF0889c	NC_008245.1	897980	898420	R	Similar to Q820M2 Fimbrial protein pilin:bacterial general secretion pathway protein H from Nitrosomonas europaea (136 aa). FASTA: opt: 216 Z-score: 280.1 E(): 1e-07 Smith-Waterman score: 218; 32.639 identity in 144 aa overlap. The pili fiber building block protein has a highly distinct primary structure; a short positively charged leader sequence, and a highly conserved and highly hydrophobic amino-terminal domain which forms the core of the pilus fiber; A variety of studies suggest that the invariant glycine (G) at -1 is required for prepilin cleavage and assembly and that the glutamate (E) at + 5 is essential for assembly and efficient N-terminal methylation but not cleavage. The region near the carboxy terminus is often hydrophilic and is stabilized by one or two disulfide bridges that may be involved in recognition of receptors. The genes with these characteristics are usually termed pilA, pilE, pilV, pilW, pilX and FimU. (Mattick John S.. 'Type IV Pili and twitching motility'. Annu. Rev. Microbiol. 2002. 56:289-314.) This protein has all the characteristics described above. ORF ftt0889c; Type IV pili fiber building block protein	complement(897980..898420)	Francisella tularensis subsp. tularensis FSC198	4199363
YP_667019.1	CDS	FTF0890c	NC_008245.1	898551	898958	R	Similar to Q8Y1X9 Type 4 fimbrial pilin signal peptide protein from Ralstonia solanacearum (168 aa). FASTA: opt: 278 Z-score: 327.6 E(): 2.1e-10 Smith-Waterman score: 292; 38.095identity in 147 aa overlap. The pili fiber building block protein has a highly distinct primary structure; a short positively charged leader sequence, and a highly conserved and highly hydrophobic amino-terminal domain which forms the core of the pilus fiber; A variety of studies suggest that the invariant glycine (G) at -1 is required for prepilin cleavage and assembly and that the glutamate (E) at + 5 is essential for assembly and efficient N-terminal methylation but not cleavage. The region near the carboxy terminus is often hydrophilic and is stabilized by one or two disulfide bridges that may be involved in recognition of receptors. The genes with these characteristics are usually termed pilA, pilE, pilV, pilW,pilX and FimU. (Mattick John S.. 'Type IV Pili and twitching motility'. Annu. Rev. Microbiol. 2002. 56:289-314.) This protein has all the characteristics described above. ORF ftt0890c; Type IV pili fiber building block protein	complement(898551..898958)	Francisella tularensis subsp. tularensis FSC198	4199364
YP_667020.1	CDS	FTF0891	NC_008245.1	899342	900061	D	Similar to Q98NS1 Hypothetical protein mlr0012 from Rhizobium loti (244 aa). FASTA: opt: 327 Z-score: 404.4 bits: 82.2 E(): 1.2e-14 Smith-Waterman score: 327; 32.308 identity in 195 aa overlap. ORF ftt0891; hypothetical protein	899342..900061	Francisella tularensis subsp. tularensis FSC198	4199365
YP_667021.1	CDS	folD	NC_008245.1	900200	901048	D	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase	900200..901048	Francisella tularensis subsp. tularensis FSC198	4199416
YP_667022.1	CDS	purM	NC_008245.1	901282	902325	D	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase	901282..902325	Francisella tularensis subsp. tularensis FSC198	4199122
YP_667023.1	CDS	purCD	NC_008245.1	902325	904637	D	Amino acids 1-327 (PurC) similar to AAR06292 SAICAR synthetase from Nicotiana tabacum (399 aa). BLAST: Expect = e-105 Identities = 187/322 (58), Positives = 236/322 (73), Gaps = 6/322 (1). Amino acids 328-770 (PurD) similar to ZP_00077753 Phosphoribosylamine-glycine ligase from Methanosarcina barkeri (433). BLAST: Expect = e-108 Identities = 204/436 (46), Positives = 285/436 (65), Gaps = 3/436 (0); fusion protein PurC/PurD	902325..904637	Francisella tularensis subsp. tularensis FSC198	4199116
YP_667024.1	CDS	purN	NC_008245.1	904641	905216	D	Similar to Q8DBC3 Folate-dependent phosphoribosylglycinamide formyltransferase from Vibrio vulnificus (212 aa). FASTA: opt: 530 Z-score: 633.0 E(): 2.1e-27 Smith-Waterman score: 530; 45.263 identity in 190 aa overlap.; phosphoribosylglycinamide formyltransferase	904641..905216	Francisella tularensis subsp. tularensis FSC198	4199123
YP_667025.1	CDS	purE	NC_008245.1	905333	905824	D	Similar to P72157 Phosphoribosylaminoimidazole carboxylase catalytic subunit from Psudomonas aeruginosa (163 aa). FASTA: opt: 719 Z-score: 894.1 E(): 6.6e-42 Smith-Waterman score: 719; 70.988 identity n 162 aa overlap; phosphoribosylaminoimidazole carboxylase,catalyic subunit	905333..905824	Francisella tularensis subsp. tularensis FSC198	4199117
YP_667026.1	CDS	purK	NC_008245.1	905828	906925	D	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit	905828..906925	Francisella tularensis subsp. tularensis FSC198	4199120
YP_667027.1	CDS	FTF0898c	NC_008245.1	906922	907275	R	Similar to Q88N88 Conserved hypothetical protein TIGR002 from Pseudomonas putida (124 aa). FASTA: opt: 291 Z-score: 402.6 E(): 1.6e-14 Smith-Waterman score: 291; 38.938 identity in 113 aa overlap. ORF ftt0898c; hypothetical protein	complement(906922..907275)	Francisella tularensis subsp. tularensis FSC198	4199366
YP_667028.1	CDS	prlC	NC_008245.1	907342	909363	R	Similar to P27298 Oligopeptidase A from Escherichia coli (680 aa). FASTA: opt: 1936 Z-score: 2040.0 E(): 8.9e-106 Smith-Waterman score: 1936; 43.722 identity in 677 aa overlap.; oligopeptidase A	complement(907342..909363)	Francisella tularensis subsp. tularensis FSC198	4199941
YP_667029.1	CDS	FTF0900	NC_008245.1	909455	909826	D	ORF ftt0900; hypothetical protein	909455..909826	Francisella tularensis subsp. tularensis FSC198	4199367
YP_667030.1	CDS	lpnA	NC_008245.1	909907	910356	D	Paralog to conserved hypothetical lipoprotein lpnB.; lipoprotein	909907..910356	Francisella tularensis subsp. tularensis FSC198	4199567
YP_667031.1	CDS	FTF0902	NC_008245.1	910515	910994	D	paralog of FTF0903 ORF ftt0902; hypothetical protein	910515..910994	Francisella tularensis subsp. tularensis FSC198	4199368
YP_667032.1	CDS	FTF0903	NC_008245.1	911094	911597	D	paralog of FTF0902 ORF ftt0903; hypothetical protein	911094..911597	Francisella tularensis subsp. tularensis FSC198	4199369
YP_667033.1	CDS	lpnB	NC_008245.1	911630	912097	D	Similar to P18149 17 kDa major membrane protein precursor from Francisella tularensis ssp. holarctica strain LVS (149 aa). FASTA: opt: 274 Z-score: 359.1 E(): 4.1e-12 Smith-Waterman score: 274; 32.468 identity (33.5570ngapped) in 154 aa overlap. Paralog to conserved hypothetical lipoprotein lpnA.; lipoprotein	911630..912097	Francisella tularensis subsp. tularensis FSC198	4199568
YP_667034.1	CDS	FTF0905	NC_008245.1	912170	913612	D	Similar to Q8KQ19 PilO from Pseudomonas aeruginosa (461 aa). FASTA: opt: 283 Z-score: 329.7 E(): 1.6e-10 Smith-Waterman score: 283; 25.284 identity in 352 aa overlap. PilO is required for glycosylation of Pseudomonas aeruginosa pilin. ORF ftt0905; Type IV pili glycosylation protein	912170..913612	Francisella tularensis subsp. tularensis FSC198	4199370
YP_667035.1	CDS	topA	NC_008245.1	913666	915960	R	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity; DNA topoisomerase I	complement(913666..915960)	Francisella tularensis subsp. tularensis FSC198	4199858
YP_667036.1	CDS	parA	NC_008245.1	916159	916800	D	Similar to Q9F260 Partition protein from Actinobacillus actinomycetemcomitans (213 aa). FASTA: opt: 286 Z-score: 339.2 E(): 4.8e-11 mith-Waterman score: 286; 29.245 identity in 212 aa overlap; chmomosome partition protein A	916159..916800	Francisella tularensis subsp. tularensis FSC198	4200093
YP_667037.1	CDS	parB	NC_008245.1	916793	917707	D	Similar to Q9CJA4 Chromosome partitioning protein from Lactococcus lactis (261 aa). FASTA: opt: 399 Z-score: 442.0 E(): 9e-17 Smith-Waterman score: 399; 33.333 identity in 264 aa overlap; chromosome partition protein B	916793..917707	Francisella tularensis subsp. tularensis FSC198	4200094
YP_667038.1	CDS	FTF0909	NC_008245.1	917721	918428	D	Similar to Q88LT5 Glutamine amidotransferase, class I from Pseudomonas putida (244 aa). FASTA: opt: 589 Z-score: 771.5 bits: 150.1 E(): 4.4e-35 Smith-Waterman score: 589; 36.325identity in 234 aa overlap. ORF ftt0909; glutamine amidotransferase	917721..918428	Francisella tularensis subsp. tularensis FSC198	4199371
YP_667039.1	CDS	FTF0910	NC_008245.1	918431	919312	D	Weakly similar to Q8GNM7 Lysophospholipase A from Legionella pneumophila (309 aa). FASTA: 86 opt: 302 Z-score: 378.8 bits: 78.1 E(): 3.3e-13 Smith-Waterman score: 360; 29.795 identity in 292 aa overlap. ORF ftt0910; hypothetical protein	918431..919312	Francisella tularensis subsp. tularensis FSC198	4199372
YP_667040.1	CDS	FTF0911	NC_008245.1	919309	919899	D	Similar with Q87NK1 Hypothetical protein from Vibrio parahaemolyticus (195 aa) fasta scores; opt: 523 Z-score: 649.0 E(): 2.7e-28 Smith-Waterman score: 523; 42.857 identity in 189 aa overlap ORF ftt0911; hypothetical protein	919309..919899	Francisella tularensis subsp. tularensis FSC198	4199373
YP_667041.1	CDS	rrmJ	NC_008245.1	919959	920579	R	Similar to Q8EHM3 Ribosomal RNA large subunit methyltransferase J from Shewanella oneidensis (209 aa). FASTA: opt: 730 Z-score: 844.0 E(): 3.7e-39 Smith-Waterman score: 730; 53.202identity in 203 aa overlap; ribosomal large subunit methyltransferase J	complement(919959..920579)	Francisella tularensis subsp. tularensis FSC198	4198962
YP_667042.1	CDS	FTF0913	NC_008245.1	920737	921204	D	ORF ftt0913; hypothetical protein	920737..921204	Francisella tularensis subsp. tularensis FSC198	4199374
YP_667043.1	CDS	lspA	NC_008245.1	921199	921684	R	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase	complement(921199..921684)	Francisella tularensis subsp. tularensis FSC198	4199651
YP_667044.1	CDS	ileS	NC_008245.1	921671	924478	R	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase	complement(921671..924478)	Francisella tularensis subsp. tularensis FSC198	4200661
YP_667045.1	CDS	ribF	NC_008245.1	924571	925491	R	Similar to Q9CKF8 RibF from Pasteurella multocida (311 aa). FASTA: opt: 845 Z-score: 994.4 E(): 1.5e-47 Smith-Waterman score: 845; 44.481 identity in 308 aa overlap; riboflavin biosynthesis protein RibF	complement(924571..925491)	Francisella tularensis subsp. tularensis FSC198	4199216
YP_667046.1	CDS	maeA	NC_008245.1	925642	927456	D	malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase	925642..927456	Francisella tularensis subsp. tularensis FSC198	4199656
YP_667047.1	CDS	FTF0918	NC_008245.1	927619	929292	D	ORF ftt0918; hypothetical protein	927619..929292	Francisella tularensis subsp. tularensis FSC198	4199375
YP_667048.1	CDS	FTF0919	NC_008245.1	929309	930754	D	ORF ftt0919; hypothetical protein	929309..930754	Francisella tularensis subsp. tularensis FSC198	4199376
YP_667049.1	CDS	isftu1	NC_008245.1	930889	931673	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(930889..931215,931215..931673)	Francisella tularensis subsp. tularensis FSC198	4199637
YP_667050.1	CDS	FTF0922	NC_008245.1	932841	933395	D	Similarity to Q98JM3 Probable fatty acid hydroxylase from Rhizobium loti (164 aa). FASTA: opt: 305 Z-score: 383.8 E(): 1.6e-13 Smith-Waterman score: 305; 31.902 identity in 163 aa overlap. ORF ftt0922; fatty acid hydroxylase	932841..933395	Francisella tularensis subsp. tularensis FSC198	4199378
YP_667051.1	CDS	rlmL	NC_008245.1	933470	935623	D	catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase	933470..935623	Francisella tularensis subsp. tularensis FSC198	4199379
YP_667052.1	CDS	FTF0924	NC_008245.1	935725	936123	D	ORF ftt0924; hypothetical protein	935725..936123	Francisella tularensis subsp. tularensis FSC198	4199380
YP_667053.1	CDS	fmt	NC_008245.1	936128	937069	D	Similarity to P44787 Methionyl-tRNA formyltransferase from Haemophilus ducreyi (318 aa). FASTA: opt: 949 Z-score: 1086.2 E(): 1.2e-52 Smith-Waterman score: 958; 48.387 identity in 310 aa overlap; methionyl-tRNA formyltransferase	936128..937069	Francisella tularensis subsp. tularensis FSC198	4199412
YP_667054.1	CDS	gshB	NC_008245.1	937073	938047	D	catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase	937073..938047	Francisella tularensis subsp. tularensis FSC198	4200363
YP_667055.1	CDS	hemL	NC_008245.1	938037	939332	D	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase	938037..939332	Francisella tularensis subsp. tularensis FSC198	4200378
YP_667056.1	CDS	FTF0928c	NC_008245.1	939353	941020	R	SImilar to Q8RD12 Beta-glucosidase-related glycosidases from Thermoanaerobacter tengcongensis (591 aa). FASTA: opt: 1047 Z-score: 1141.5 E(): 9.9e-56 Smith-Waterman score: 1062; 35.106 identity in 564 aa overlap. ORF ftt0928c; beta-glucosidase	complement(939353..941020)	Francisella tularensis subsp. tularensis FSC198	4199381
YP_667057.1	CDS	FTF0931	NC_008245.1	942762	944021	D	Similar to Q89YS8 Glucose/galactose transporter from Bacteroides thetaiotaomicron (415 aa). FASTA: opt: 1125 Z-score: 1176.3 bits: 226.6 E(): 1.3e-57 Smith-Waterman score: 1125; 41.446 identity in 415 aa overlap ORF ftt0931; major facilitator transporter	942762..944021	Francisella tularensis subsp. tularensis FSC198	4200027
YP_667058.1	CDS	FTF0932	NC_008245.1	944056	944907	D	Similar to Q8A1Q9 ROK family transcriptional repressor from Bacteroides thetaiotaomicron (298 aa). FASTA: opt: 482 Z-score: 605.6 E(): 7.7e-26 Smith-Waterman score: 482; 30.769 identity in 286 aa overlap ORF ftt0932; ROK family protein	944056..944907	Francisella tularensis subsp. tularensis FSC198	4200028
YP_667059.1	CDS	bioD	NC_008245.1	945833	946510	R	Similar to AAO90524 Dethiobiotin synthetase from Coxiella burnetii (242 aa). FASTA: opt: 464 Z-score: 551.2 E(): 7.5e-23 Smith-Waterman score: 464; 34.498 identity in 229 aa overlap; dethiobiotin synthetase	complement(945833..946510)	Francisella tularensis subsp. tularensis FSC198	4200306
YP_667060.1	CDS	bioC	NC_008245.1	946514	947251	R	Similar to AAO90525 Biotin synthesis protein BioC,putative from Coxiella burnetii (248 aa) FASTA: opt: 232 Z-score: 273.5 E(): 2.2e-07 Smith-Waterman score: 232; 23.293 identity in 249 aa overlap; biotin synthesis protein BioC	complement(946514..947251)	Francisella tularensis subsp. tularensis FSC198	4200305
YP_667061.1	CDS	bioF	NC_008245.1	947229	948356	R	Similar to AAO90527 8-amino-7-oxononanoate synthase (384 aa) fasta scores; opt: 763 Z-score: 912.3 E(): 5.8e-43 Smith-Waterman score: 763; 39.053identity in 338 aa overlap; 8-amino-7-oxononanoate synthase	complement(947229..948356)	Francisella tularensis subsp. tularensis FSC198	4200307
YP_667062.1	CDS	bioB	NC_008245.1	948350	949291	R	Similar to AAO90528 Biotin synthase from Coxiella burnetii (321 aa) FASTA: opt: 1220 Z-score: 1430.1 E(): 8.3e-72 Smith-Waterman score: 1220; 60.396 identity in 303 aa overlap; biotin synthase	complement(948350..949291)	Francisella tularensis subsp. tularensis FSC198	4199704
YP_667063.1	CDS	bioA	NC_008245.1	949337	950668	D	Similar to AAO90529 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase from Coxiella burnetii (442 aa). FASTA: opt: 1486 Z-score: 1733.9 E(): 9.9e-89 Smith-Waterman score: 1486; 50.588 identity in 425 aa overlap; adenosylmethionine-8-amino-7-oxononanoate aminotransferase	949337..950668	Francisella tularensis subsp. tularensis FSC198	4199703
YP_667064.1	CDS	add1	NC_008245.1	950778	951722	R	catalyzes the formation of inosine from adenosine; adenosine deaminase	complement(950778..951722)	Francisella tularensis subsp. tularensis FSC198	4199756
YP_667065.1	CDS	FTF0940c	NC_008245.1	951870	952370	R	Similar to Q88CI3 Conserved hypothetical protein from Pseudomonas putida (160 aa). FASTA: opt: 297 Z-score: 384.8 E(): 1.4e-13 Smith-Waterman score: 297; 32.653 identity in 147 aa overlap ORF ftt0940c; hypothetical protein	complement(951870..952370)	Francisella tularensis subsp. tularensis FSC198	4200030
YP_667066.1	CDS	FTF0941c	NC_008245.1	952386	953306	R	Similar to Q97VW1 Lipase (lipP-1) from Sulfolobus solfataricus (305 aa). FASTA: opt: 488 Z-score: 622.4 E(): 8.9e-27 Smith-Waterman score: 488; 32.990 identity in 291 aa overlap. ORF ftt0941c; lipase/esterase	complement(952386..953306)	Francisella tularensis subsp. tularensis FSC198	4200031
YP_667067.1	CDS	folK	NC_008245.1	953319	954584	R	Similar to Q821E2 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase from Chlamydophila caviae (447 aa). FASTA: opt: 517 Z-score: 602.2 E(): 1.2e-25 Smith-Waterman score: 604; 30.664 identity in 437 aa overlap; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase	complement(953319..954584)	Francisella tularensis subsp. tularensis FSC198	4199418
YP_667068.1	CDS	folB	NC_008245.1	954586	954939	R	Similar to O84620 Probable dihydroneopterin aldolase (124 aa) fasta scores; opt: 191 Z-score: 262.4 E(): 9.2e-07 Smith-Waterman score: 191; 30.189identity in 106 aa overlap; dihydroneopterin aldolase	complement(954586..954939)	Francisella tularensis subsp. tularensis FSC198	4199414
YP_667069.1	CDS	FTF0944	NC_008245.1	955009	956391	D	Similar to Q9CHK3 O-succinylbenzoic acid-CoA ligase from Lactococcus lactis (420 aa). opt: 373 Z-score: 423.0 E(): 1e-15 Smith-Waterman score: 434; 27.692 identity in 390 aa overlap ORF ftt0944; AMP-binding family protein	955009..956391	Francisella tularensis subsp. tularensis FSC198	4200032
YP_667070.1	CDS	FTF0945	NC_008245.1	956384	958147	D	Similar to Q8ESD8 Para-aminobenzoate synthase component II (585 aa) fasta scores; opt: 1108 Z-score: 1235.5 E(): 5.7e-61 Smith-Waterman score: 1108; 33.851 identity in 579 aa overlap. ORF ftt0945; chorismate binding family protein	956384..958147	Francisella tularensis subsp. tularensis FSC198	4200033
YP_667071.1	CDS	trpG1	NC_008245.1	958149	958703	D	Similarity to Q972A0 Putative anthranilate synthase component from Sulfolobus tokodaii (193 aa). FASTA: opt: 499 Z-score: 620.3 E(): 1.1e-26 Smith-Waterman score: 499; 40.741 identity in 189 aa overlap. Closely related to pabA proteins as they possess a shared domain feature; anthranilate synthase component II	958149..958703	Francisella tularensis subsp. tularensis FSC198	4200720
YP_667072.1	CDS	FTF0948c	NC_008245.1	959924	960988	R	Similar to Q92QZ5 Putative oxidoreductase protein from Rhizobium meliloti (347 aa). FASTA: opt: 1125 Z-score: 1304.5 E(): 8.2e-65 Smith-Waterman score: 1125; 50.140 identity in 357 aa overlap. putative pseudogene: flanked by pseudogenes ORF ftt0948c; aldo/keto reductase	complement(959924..960988)	Francisella tularensis subsp. tularensis FSC198	4200035
YP_667073.1	CDS	folE	NC_008245.1	963351	963971	R	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I	complement(963351..963971)	Francisella tularensis subsp. tularensis FSC198	4199417
YP_667074.1	CDS	rhlE	NC_008245.1	964098	965423	D	Similar to Q8D6C6 Superfamily II DNA and RNA helicase from Vibrio vulnificus (509 aa). FASTA: opt: 1533 Z-score: 1649.9 E(): 4.8e-84 Smith-Waterman score: 1533; 56.036 identity in 439 aa overlap; ATP-dependent RNA helicase RhlE	964098..965423	Francisella tularensis subsp. tularensis FSC198	4199210
YP_667075.1	CDS	FTF0953c	NC_008245.1	965420	966961	R	Similar to Q9KTB5 Proton/peptide symporter family protein from Vibrio cholerae (514 aa). FASTA: opt: 1329 Z-score: 1443.3 E(): 1.5e-72 Smith-Waterman score: 1329; 42.629identity in 502 aa overlap. ORF ftt0953c; proton-dependent oligopeptide transport (POT) family protein	complement(965420..966961)	Francisella tularensis subsp. tularensis FSC198	4200038
YP_667076.1	CDS	FTF0954c	NC_008245.1	967099	967419	R	Similar to O29392 Hypothetical protein AF0869 from Archaeoglobus fulgidus (108 aa). FASTA: opt: 272 Z-score: 377.5 E(): 3.9e-13 Smith-Waterman score: 272; 42.056 identity in 107 aa overlap ORF ftt0954c; hypothetical protein	complement(967099..967419)	Francisella tularensis subsp. tularensis FSC198	4200039
YP_667077.1	CDS	gor	NC_008245.1	967430	968791	R	catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase	complement(967430..968791)	Francisella tularensis subsp. tularensis FSC198	4200292
YP_667078.1	CDS	FTF0956c	NC_008245.1	968829	969548	R	Similar to AAO50751 (Q86L42) Hypothetical protein from Dictyostelium discoideum (239 aa). FASTA: opt: 229 Z-score: 273.3 E(): 2.3e-07 Smith-Waterman score: 253; 29.437 identity in 231 aa overlap ORF ftt0956c; hypothetical protein	complement(968829..969548)	Francisella tularensis subsp. tularensis FSC198	4200040
YP_667079.1	CDS	FTF0957c	NC_008245.1	969548	970051	R	Similar to Q83YE2 Shy8 from Streptomyces hygroscopicus (163 aa). FASTA: opt: 343 Z-score: 413.4 bits: 82.8 E(): 3.9e-15 Smith-Waterman score: 343; 36.420 identity in 162 aa overlap. ORF ftt0957c; hypothetical protein	complement(969548..970051)	Francisella tularensis subsp. tularensis FSC198	4200041
YP_667080.1	CDS	FTF0958c	NC_008245.1	970054	970761	R	Similar to Q9HWL9 Probable short-chain dehydrogenase from Pseudomonas aeruginosa (238 aa). FASTA: opt: 848 Z-score: 1032.8 E(): 1.1e-49 Smith-Waterman score: 848; 55.932 identity in 236 aa overlap ORF ftt0958c; short chain dehydrogenase	complement(970054..970761)	Francisella tularensis subsp. tularensis FSC198	4200042
YP_667081.1	CDS	xthA	NC_008245.1	970782	971570	R	Similar to Q83EM1 Exodeoxyribonuclease III from Coxiella burnetii (259 aa). FASTA: opt: 991 Z-score: 1173.5 E(): 1.6e-57 Smith-Waterman score: 991; 54.789 identity in 261 aa overlap; exodeoxyribonuclease III	complement(970782..971570)	Francisella tularensis subsp. tularensis FSC198	4200696
YP_667082.1	CDS	FTF0960	NC_008245.1	971854	972837	D	Simiar to Q8EAC2 Conserved hypothetical protein Shewanella oneidensis (371 aa). FASTA: opt: 607 Z-score: 717.9 E(): 3.9e-32 Smith-Waterman score: 607; 32.622 identity in 328 aa overlap ORF ftt0960; hypothetical protein	971854..972837	Francisella tularensis subsp. tularensis FSC198	4200043
YP_667083.1	CDS	mdaB	NC_008245.1	972845	973435	D	Similar to P40717 Modulator of drug activity B from Escherichia coli (193 aa). FASTA: opt: 900 Z-score: 1129.6 E(): 4.5e-55 Smith-Waterman score: 900; 63.542 identity in 192 aa overlap.; modulator of drug activity B	972845..973435	Francisella tularensis subsp. tularensis FSC198	4199662
YP_667084.1	CDS	FTF0962	NC_008245.1	973551	974213	D	Similar to Q87Z85 ThiJ/PfpI family protein from Pseudomonas syringae (225 aa). FASTA: opt: 570 Z-score: 665.3 E(): 3.3e-29 Smith-Waterman score: 570; 38.991 identity in 218 aa overlap ORF ftt0962; ThiJ/PfpI family protein	973551..974213	Francisella tularensis subsp. tularensis FSC198	4199323
YP_667085.1	CDS	aroG	NC_008245.1	974283	975395	R	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase	complement(974283..975395)	Francisella tularensis subsp. tularensis FSC198	4199437
YP_667086.1	CDS	ffh	NC_008245.1	975427	976803	R	Similar to Q9CLN6 Ffh from Pasteurella multocida (458 aa). FASTA: opt: 1851 Z-score: 1789.9 E(): 7.5e-92 Smith-Waterman score: 1851; 61.790 identity in 458 aa overlap; signal recognition particle protein, Ffh	complement(975427..976803)	Francisella tularensis subsp. tularensis FSC198	4199410
YP_667087.1	CDS	FTF0965c	NC_008245.1	977147	978052	R	Similar to Q928M9 Hypothetical protein lin2503 from Listeria innocua (279 aa). FASTA: opt: 733 Z-score: 821.7 E(): 6.4e-38 Smith-Waterman score: 733; 41.852 identity in 270 aa overlap. ORF ftt0965c; hypothetical protein	complement(977147..978052)	Francisella tularensis subsp. tularensis FSC198	4199324
YP_667088.1	CDS	infA	NC_008245.1	978146	978364	D	stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1	978146..978364	Francisella tularensis subsp. tularensis FSC198	4199609
YP_667089.1	CDS	FTF0968c	NC_008245.1	979326	980741	R	Similar to Q83BZ0 Amino acid antiporter from Coxiella burnetii (474 aa). FASTA: 432 opt: 1275 Z-score: 1361.2 E(): 6.3e-68 Smith-Waterman score: 1275; 40.171 identity in 468 aa overlap. ORF ftt0968c; amino acid antiporter	complement(979326..980741)	Francisella tularensis subsp. tularensis FSC198	4199326
YP_667090.1	CDS	trkA	NC_008245.1	980806	982179	R	involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein	complement(980806..982179)	Francisella tularensis subsp. tularensis FSC198	4199861
YP_667091.1	CDS	FTF0970	NC_008245.1	982332	982742	D	Similar to Q8PIG4 Hypothetical protein XAC2934 from Xanthomonas axonopodis (152 aa). FASTA: opt: 281 Z-score: 360.3 E(): 3.2e-12 Smith-Waterman score: 281; 33.588 identity in 131 aa overlap ORF ftt0970; hypothetical protein	982332..982742	Francisella tularensis subsp. tularensis FSC198	4199327
YP_667092.1	CDS	FTF0971	NC_008245.1	982749	984194	D	with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB	982749..984194	Francisella tularensis subsp. tularensis FSC198	4199328
YP_667093.1	CDS	FTF0972	NC_008245.1	984233	984982	D	Similar to Q8PIG2 ABC transporter ATP-binding protein from Xanthomonas axonopodis (254 aa). FASTA: opt: 1080 Z-score: 1117.5 E(): 2.1e-54 Smith-Waterman score: 1080; 65.041 identity in 246 aa overlap. ORF ftt0972; ABC transporter ATP-binding protein	984233..984982	Francisella tularensis subsp. tularensis FSC198	4199329
YP_667094.1	CDS	FTF0973	NC_008245.1	984986	986140	D	Similar to Q83BX9 Hypothetical protein CBU1358 Coxiella burnetii (426 aa). FASTA: opt: 433 Z-score: 493.2 E(): 1.3e-19 Smith-Waterman score: 460; 29.282 identity in 362 aa overlap ORF ftt0973; hypothetical protein	984986..986140	Francisella tularensis subsp. tularensis FSC198	4199330
YP_667095.1	CDS	FTF0975	NC_008245.1	987109	987798	D	Weakly similar to Q83CZ8 Hypothetical protein Coxiella burnetii (227 aa) 76 opt: 235 Z-score: 276.0 bits: 58.3 E(): 1.8e-07 Smith-Waterman score: 235; 25.000 identity in 236 aa overlap. ORF ftt0975; hypothetical protein	987109..987798	Francisella tularensis subsp. tularensis FSC198	4199332
YP_667096.1	CDS	trxA2	NC_008245.1	987802	988128	D	Similar to P37395 Thioredoxin from Cyanidium caldarium (107 aa) fasta scores; opt: 333 Z-score: 452.0 E(): 2.5e-17 Smith-Waterman score: 333; 45.098identity in 102 aa overlap; thioredoxin	987802..988128	Francisella tularensis subsp. tularensis FSC198	4198970
YP_667097.1	CDS	FTF0977c	NC_008245.1	988527	988820	R	Similar to Q89DD5 Bsl7504 protein from Bradyrhizobium japonicum (99 aa). FASTA: opt: 209 Z-score: 292.0 E(): 2e-08 Smith-Waterman score: 209; 38.462 identity in 91 aa overlap ORF ftt0977c; hypothetical protein	complement(988527..988820)	Francisella tularensis subsp. tularensis FSC198	4199333
YP_667098.1	CDS	FTF0978c	NC_008245.1	988824	989429	R	ORF ftt0978c; hypothetical protein	complement(988824..989429)	Francisella tularensis subsp. tularensis FSC198	4199334
YP_667099.1	CDS	FTF0979c	NC_008245.1	989483	990850	R	amino-acid permease, similarity to P39137 Amino-acid permease rocE from Bacillus subtilis (467 aa). FASTA: opt: 1272 Z-score: 1431.9 E(): 6.6e-72 Smith-Waterman score: 1272; 40.919 identity in 457 aa overlap. ORF ftt0979c; amino-acid permease	complement(989483..990850)	Francisella tularensis subsp. tularensis FSC198	4199335
YP_667100.1	CDS	FTF0980	NC_008245.1	991085	992326	D	Similar to Q8UKI4 Aminotransferase, class II from Agrobacterium tumefaciens (413 aa). FASTA: opt: 486 Z-score: 559.2 E(): 2.7e-23 Smith-Waterman score: 554; 28.493 identity in 365 aa overlap ORF ftt0980; hypothetical protein	991085..992326	Francisella tularensis subsp. tularensis FSC198	4199336
YP_667101.1	CDS	FTF0981	NC_008245.1	992659	993789	D	Weak homology to two-component sensory protein. ORF ftt0981; hypothetical protein	992659..993789	Francisella tularensis subsp. tularensis FSC198	4199337
YP_667102.1	CDS	FTF0982	NC_008245.1	993882	994025	D	ORF ftt0982; hypothetical protein	993882..994025	Francisella tularensis subsp. tularensis FSC198	4199338
YP_667103.1	CDS	FTF0983	NC_008245.1	994009	994152	D	ORF ftt0983; hypothetical protein	994009..994152	Francisella tularensis subsp. tularensis FSC198	4199339
YP_667104.1	CDS	mutT	NC_008245.1	994739	995149	R	Similar to Q87SF6 Mutator MutT protein from Vibrio parahaemolyticus (132 aa). FASTA: opt: 268 Z-score: 340.9 E(): 3.9e-11 Smith-Waterman score: 268; 29.545identity in 132 aa overlap.; Mutator protein	complement(994739..995149)	Francisella tularensis subsp. tularensis FSC198	4200115
YP_667105.1	CDS	FTF0985	NC_008245.1	995188	995772	D	Similar to Q8EBZ9 Conserved hypothetical protein from Shewanella oneidensis (187 aa). FASTA: opt: 386 Z-score: 477.0 E(): 1e-18 Smith-Waterman score: 386; 36.022 identity in 186 aa overlap ORF ftt0985; hypothetical protein	995188..995772	Francisella tularensis subsp. tularensis FSC198	4199340
YP_667106.1	CDS	FTF0986	NC_008245.1	995774	996184	D	Similar to Q9L3I7 Putative Holliday junction resolvase from Aeromonas hydrophila (140 aa). FASTA: opt: 336 Z-score: 430.0 E(): 4.7e-16 Smith-Waterman score: 336; 36.567 identity in 134 aa overlap Putative Holliday junction resolvase predicted in other proteins ORF ftt0986; hypothetical protein	995774..996184	Francisella tularensis subsp. tularensis FSC198	4199341
YP_667107.1	CDS	FTF0987	NC_008245.1	996277	996474	D	ORF ftt0987; hypothetical protein	996277..996474	Francisella tularensis subsp. tularensis FSC198	4199342
YP_667108.1	CDS	FTF0988	NC_008245.1	996597	996785	D	ORF ftt0988; hypothetical protein	996597..996785	Francisella tularensis subsp. tularensis FSC198	4199305
YP_667109.1	CDS	FTF0989	NC_008245.1	996879	998774	D	Similar to Q9I271 Hypothetical protein PA2044 from Pseudomonas aeruginosa (624 aa). FASTA: opt: 447 Z-score: 484.0 E(): 4.2e-19 Smith-Waterman score: 447; 22.203 identity in 572 aa overlap. ORF ftt0989; hypothetical protein	996879..998774	Francisella tularensis subsp. tularensis FSC198	4199306
YP_667110.1	CDS	leuS	NC_008245.1	998882	1001323	D	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase	998882..1001323	Francisella tularensis subsp. tularensis FSC198	4199514
YP_667111.1	CDS	FTF0991	NC_008245.1	1001331	1001906	D	ORF ftt0991; lipoprotein	1001331..1001906	Francisella tularensis subsp. tularensis FSC198	4199307
YP_667112.1	CDS	FTF0992	NC_008245.1	1001967	1003157	D	Similar to Q8A7A2 Putative membrane protein from Bacteroides thetaiotaomicron (391 aa). FASTA: opt: 908 Z-score: 1062.3 E(): 2.6e-51 Smith-Waterman score: 908; 37.637 identity in 364 aa overlap. ORF ftt0992; hypothetical protein	1001967..1003157	Francisella tularensis subsp. tularensis FSC198	4199308
YP_667113.1	CDS	dcd	NC_008245.1	1003164	1003730	R	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase	complement(1003164..1003730)	Francisella tularensis subsp. tularensis FSC198	4199527
YP_667114.1	CDS	FTF0994c	NC_008245.1	1003742	1004602	R	Similar to Q8XWU1 Probable MRP protein ATP-binding from Ralstonia solanacearum. (362 aa). FASTA: opt: 1008 Z-score: 1105.3 E(): 1e-53 Smith-Waterman score: 1008; 52.688 identity in 279 aa overlap. ORF ftt0994c; MRP like protein	complement(1003742..1004602)	Francisella tularensis subsp. tularensis FSC198	4199309
YP_667115.1	CDS	FTF0995	NC_008245.1	1004676	1005908	D	Similarity to Q8UDH1 MFS permease[proline/betaine] from Agrobacterium tumefaciens (443 aa). FASTA: opt: 727 Z-score: 824.0 E(): 4.8e-38 Smith-Waterman score: 828; 35.507identity in 414 aa overlap ORF ftt0995; major facilitator transporter	1004676..1005908	Francisella tularensis subsp. tularensis FSC198	4199310
YP_667116.1	CDS	ybhO	NC_008245.1	1007478	1008908	D	Similar to P71040 Probable cardiolipin synthetase 2 from Bacillus subtilis (482 aa). FASTA: opt: 835 Z-score: 944.7 E(): 9.1e-45 Smith-Waterman score: 835; 32.525 identity in 495 aa overlap; cardiolipin synthetase	1007478..1008908	Francisella tularensis subsp. tularensis FSC198	4200705
YP_667117.1	CDS	FTF0998	NC_008245.1	1009074	1010063	D	ORF ftt0998; hypothetical protein	1009074..1010063	Francisella tularensis subsp. tularensis FSC198	4199312
YP_667118.1	CDS	cobS	NC_008245.1	1010831	1012057	R	Similar to Q8FUU8 Cobalamin synthesis protein/P47K family protein from Brucella suis (400 aa). FASTA: opt: 1643 Z-score: 1956.7 E(): 4.3e-101 Smith-Waterman score: 1643; 58.396 identity in 399 aa overlap.; cobalamin (vitamin B12) synthesis protein/P47K family protein	complement(1010831..1012057)	Francisella tularensis subsp. tularensis FSC198	4200272
YP_667119.1	CDS	FTF1001	NC_008245.1	1012199	1012630	D	Similar to Q8ZJ15 Putative regulatory protein from Yersinia pestis (169 aa). FASTA: opt: 313 Z-score: 406.8 E(): 9.2e-15 Smith-Waterman score: 313; 36.429 identity in 140 aa overlap. ORF ftt1001; regulatory protein	1012199..1012630	Francisella tularensis subsp. tularensis FSC198	4199314
YP_667120.1	CDS	pheT	NC_008245.1	1012673	1015045	R	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta	complement(1012673..1015045)	Francisella tularensis subsp. tularensis FSC198	4199725
YP_667121.1	CDS	pheS	NC_008245.1	1015066	1016079	R	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha	complement(1015066..1016079)	Francisella tularensis subsp. tularensis FSC198	4199724
YP_667122.1	CDS	FTF1004c	NC_008245.1	1016165	1017058	R	Similar to Q9RX03 Hypothetical protein DR0512 from Deinococcus radiodurans (301 aa). Similar to opt: 577 Z-score: 644.6 E(): 5.1e-28 Smith-Waterman score: 577; 33.094 identity in 278 aa overlap. ORF ftt1004c; hypothetical protein	complement(1016165..1017058)	Francisella tularensis subsp. tularensis FSC198	4199315
YP_667123.1	CDS	yhiP	NC_008245.1	1017083	1018558	R	Similar to Q8X5Q8 Putative transport protein from Escherichia coli (489 aa). FASTA: opt: 1050 Z-score: 1137.7 E(): 1.8e-55 Smith-Waterman score: 1050; 35.569 identity in 492 aa overlap.; proton-dependent oligopeptide transporter (POT) family protein	complement(1017083..1018558)	Francisella tularensis subsp. tularensis FSC198	4199106
YP_667124.1	CDS	FTF1006	NC_008245.1	1018802	1020010	D	ORF ftt1006; hypothetical protein	1018802..1020010	Francisella tularensis subsp. tularensis FSC198	4199316
YP_667125.1	CDS	FTF1007c	NC_008245.1	1019995	1020717	R	ORF ftt1007c; hypothetical protein	complement(1019995..1020717)	Francisella tularensis subsp. tularensis FSC198	4199317
YP_667126.1	CDS	FTF1008c	NC_008245.1	1020778	1020942	R	ORF ftt1008c; hypothetical protein	complement(1020778..1020942)	Francisella tularensis subsp. tularensis FSC198	4199318
YP_667127.1	CDS	FTF1009	NC_008245.1	1021070	1021606	D	ORF ftt1009; hypothetical protein	1021070..1021606	Francisella tularensis subsp. tularensis FSC198	4199319
YP_667128.1	CDS	FTF1010	NC_008245.1	1021621	1021824	D	Similar to Q81BZ8 Transcriptional regulator,Cro/CI family protein from Bacillus cereus (strain ATCC 14579 / DSM 31) (71 aa). FASTA: opt: 263 Z-score: 391.6 E(): 6.4e-14 Smith-Waterman score: 263; 60.606 identity in 66 aa overlap. ORF ftt1010; helix-turn-helix family protein	1021621..1021824	Francisella tularensis subsp. tularensis FSC198	4199320
YP_667129.1	CDS	FTF1011	NC_008245.1	1021936	1022124	D	ORF ftt1011; hypothetical protein	1021936..1022124	Francisella tularensis subsp. tularensis FSC198	4199321
YP_667130.1	CDS	ruvB	NC_008245.1	1023111	1024157	R	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB	complement(1023111..1024157)	Francisella tularensis subsp. tularensis FSC198	4198966
YP_667131.1	CDS	FTF1014c	NC_008245.1	1024221	1024946	R	Similar to YWFD_BACSU (P39640) Hypothetical oxidoreductase ywfD from Bacillus subtilis (255 aa). FASTA: opt: 410 Z-score: 474.7 E(): 1.5e-18 Smith-Waterman score: 471; 38.710 identity in 248 aa overlap. ORF ftt1014c; short chain dehydrogenase family protein	complement(1024221..1024946)	Francisella tularensis subsp. tularensis FSC198	4200667
YP_667132.1	CDS	FTF1015	NC_008245.1	1025064	1025654	D	ORF ftt1015; hypothetical protein	1025064..1025654	Francisella tularensis subsp. tularensis FSC198	4200668
YP_667133.1	CDS	FTF1016c	NC_008245.1	1025664	1026293	R	Similar to Q9JQY7 Putative lipase (GDSL lipase family protein) from Neisseria meningitidis (213 aa). FASTA: opt: 358 Z-score: 439.3 E(): 1.4e-16 Smith-Waterman score: 358; 32.203 identity in 177 aa overlap. ORF ftt1016c; GDSL-like lipase/acylhydrolase family protein	complement(1025664..1026293)	Francisella tularensis subsp. tularensis FSC198	4200669
YP_667134.1	CDS	FTF1017c	NC_008245.1	1026315	1026650	R	ORF ftt1017c; hypothetical protein	complement(1026315..1026650)	Francisella tularensis subsp. tularensis FSC198	4200670
YP_667135.1	CDS	dxs	NC_008245.1	1026666	1028513	R	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase	complement(1026666..1028513)	Francisella tularensis subsp. tularensis FSC198	4199668
YP_667136.1	CDS	guaA	NC_008245.1	1028595	1030145	R	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase	complement(1028595..1030145)	Francisella tularensis subsp. tularensis FSC198	4200365
YP_667137.1	CDS	FTF1020c	NC_008245.1	1030233	1031780	R	Similar to Q83EA0 Amino acid permease family protein from Coxiella burnetii (531 aa). FASTA: opt: 925 Z-score: 996.3 E(): 1.3e-47 Smith-Waterman score: 947; 29.379 identity in 531 aa overlap. ORF ftt1020c; amino acid permease	complement(1030233..1031780)	Francisella tularensis subsp. tularensis FSC198	4200671
YP_667138.1	CDS	truA	NC_008245.1	1031833	1032609	R	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A	complement(1031833..1032609)	Francisella tularensis subsp. tularensis FSC198	4200724
YP_667139.1	CDS	FTF1022c	NC_008245.1	1032612	1034444	R	Similar to Y125_PYRHO (O57865) Hypothetical protein PH0125 from Pyrococcus horikoshii (257 aa) (from 1-260). FASTA: opt: 520 Z-score: 632.1 E(): 2.6e-27 Smith-Waterman score: 520; 35.600 identity in 250 aa overlap AND Q97VT8 Lipase (lipP-2) (EC 3.1.1.3) from Sulfolobus solfataricus (311 aa) (from 300-610). FASTA: opt: 613 Z-score: 743.7 E(): 1.6e-33 Smith-Waterman score: 613; 34.586 identity in 266 aa overlap Possible merged protein due to a missing stop codon between 2 CDSs? ORF ftt1022c; hypothetical protein	complement(1032612..1034444)	Francisella tularensis subsp. tularensis FSC198	4200672
YP_667140.1	CDS	FTF1023c	NC_008245.1	1034457	1035050	R	Similar to Q8EGL6 Fumarylacetoacetate hydrolase family protein from Shewanella oneidensis (208 aa). FASTA: opt: 599 Z-score: 746.5 E(): 1.1e-33 Smith-Waterman score: 599; 51.913 identity in 183 aa overlap. ORF ftt1023c; fumarylacetoacetate hydrolase family protein	complement(1034457..1035050)	Francisella tularensis subsp. tularensis FSC198	4200673
YP_667141.1	CDS	yhbG	NC_008245.1	1035099	1035830	R	Similar to Q8ZB44 Probable ABC transporter ATP-binding protein from Yersinia pestis (241 aa). FASTA: opt: 1091 Z-score: 1233.5 E(): 8.2e-61 Smith-Waterman score: 1091; 65.690 identity in 239 aa overlap.; ABC transporter ATP-binding protein	complement(1035099..1035830)	Francisella tularensis subsp. tularensis FSC198	4199102
YP_667142.1	CDS	FTF1025c	NC_008245.1	1035904	1036737	R	ORF ftt1025c; hypothetical protein	complement(1035904..1036737)	Francisella tularensis subsp. tularensis FSC198	4200674
YP_667143.1	CDS	FTF1026c	NC_008245.1	1036724	1037350	R	ORF ftt1026c; hypothetical protein	complement(1036724..1037350)	Francisella tularensis subsp. tularensis FSC198	4200675
YP_667144.1	CDS	yrbI	NC_008245.1	1037358	1037906	R	Similar to AAP18518 Hypothetical protein yrbI from Escherichia coli (188 aa). FASTA: initn: 454 init1: 247 opt: 453 Z-score: 558.6 bits: 110.0 E(): 3.2e-23 Smith-Waterman score: 453; 50.000 identity in 152 aa overlap.; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	complement(1037358..1037906)	Francisella tularensis subsp. tularensis FSC198	4199035
YP_667145.1	CDS	ppa	NC_008245.1	1037997	1038518	R	Similar to IPYR_YERPE (Q8ZB98) Inorganic pyrophosphatase from Yersinia pestis (175 aa). FASTA: opt: 762 Z-score: 1001.4 E(): 6.9e-48 Smith-Waterman score: 762; 62.209 identity in 172 aa overlap.; inorganic pyrophosphatase	complement(1037997..1038518)	Francisella tularensis subsp. tularensis FSC198	4199932
YP_667146.1	CDS	dacD	NC_008245.1	1038675	1040009	D	Similar to Q87VW4 D-alanyl-D-alanine carboxypeptidase from Pseudomonas syringae (pv. tomato) (386 aa). FASTA: opt: 602 Z-score: 704.0 E(): 2.5e-31 Smith-Waterman score: 794; 36.409 identity in 401 aa overlap.; D-alanyl-D-alanine carboxypeptidase	1038675..1040009	Francisella tularensis subsp. tularensis FSC198	4199526
YP_667147.1	CDS	FTF1030	NC_008245.1	1040042	1040326	D	Similar to YE87_NITEU (Q82UJ7) Hypothetical UPF0250 protein NE1487 from Nitrosomonas europaea (87 aa). FASTA: opt: 235 Z-score: 328.5 E(): 2.1e-10 Smith-Waterman score: 235; 36.471 identity in 85 aa overlap. ORF ftt1030; hypothetical protein	1040042..1040326	Francisella tularensis subsp. tularensis FSC198	4200676
YP_667148.1	CDS	lipB	NC_008245.1	1040336	1040956	D	lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B	1040336..1040956	Francisella tularensis subsp. tularensis FSC198	4199555
YP_667149.1	CDS	ndh	NC_008245.1	1045025	1046287	R	Similar to Q8UDU6 NADH dehydrogenase from Agrobacterium tumefaciens (strain C58 / ATCC 33970) (438 aa). FASTA: opt: 826 Z-score: 983.7 E(): 6.7e-47 Smith-Waterman score: 826; 32.854 identity in 417 aa overlap.; NADH dehydrogenase	complement(1045025..1046287)	Francisella tularensis subsp. tularensis FSC198	4200237
YP_667150.1	CDS	rpoD	NC_008245.1	1046394	1048127	R	Similar to P77890 LprpoD (RNA polymerase sigma factor) from Legionella pneumophila (620 aa). FASTA: opt: 1367 Z-score: 1480.9 E(): 1.4e-74 Smith-Waterman score: 1624; 47.182 identity in 621 aa overlap.; RNA polymerase sigma-70 factor	complement(1046394..1048127)	Francisella tularensis subsp. tularensis FSC198	4200330
YP_667151.1	CDS	dnaG	NC_008245.1	1048147	1049964	R	Similar to Q8DEG2 DNA primase from Vibrio vulnificus (587 aa). FASTA: opt: 1152 Z-score: 1324.3 E(): 7.2e-66 Smith-Waterman score: 1155; 39.679 identity in 499 aa overlap.; DNA primase	complement(1048147..1049964)	Francisella tularensis subsp. tularensis FSC198	4199353
YP_667152.1	CDS	FTF1037c	NC_008245.1	1049985	1050431	R	Similar to Q87SL6 Conserved hypothetical protein from Vibrio parahaemolyticus (147 aa). FASTA: opt: 473 Z-score: 548.0 E(): 1.2e-22 Smith-Waterman score: 473; 47.586 identity in 145 aa overlap. ORF ftt1037c; hypothetical protein	complement(1049985..1050431)	Francisella tularensis subsp. tularensis FSC198	4200678
YP_667153.1	CDS	rpsU	NC_008245.1	1050492	1050689	R	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21	complement(1050492..1050689)	Francisella tularensis subsp. tularensis FSC198	4198961
YP_667154.1	CDS	dacB1	NC_008245.1	1050945	1052348	D	Similar to Q83FD1 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase from Coxiella burnetii (477 aa). FASTA: opt: 654 Z-score: 780.3 E(): 1.4e-35 Smith-Waterman score: 654; 29.436 identity in 479 aa overlap.; D-alanyl-D-alanine carboxypeptidase	1050945..1052348	Francisella tularensis subsp. tularensis FSC198	4199524
YP_667155.1	CDS	FTF1040	NC_008245.1	1052349	1052960	D	Similar to Q8EBG1 Conserved hypothetical protein from Shewanella oneidensis (205 aa). FASTA: opt: 610 Z-score: 776.5 E(): 2.3e-35 Smith-Waterman score: 610; 45.810 identity in 179 aa overlap. ORF ftt1040; lipoprotein	1052349..1052960	Francisella tularensis subsp. tularensis FSC198	4200679
YP_667156.1	CDS	FTF1041	NC_008245.1	1052976	1053392	D	Similar to Q8ESG1 Hypothetical conserved protein from Oceanobacillus iheyensis (134 aa). FASTA: opt: 215 Z-score: 303.3 E(): 5.3e-09 Smith-Waterman score: 215; 32.773 identity in 119 aa overlap. ORF ftt1041; hypothetical protein	1052976..1053392	Francisella tularensis subsp. tularensis FSC198	4200680
YP_667157.1	CDS	FTF1042	NC_008245.1	1053385	1054188	D	TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase	1053385..1054188	Francisella tularensis subsp. tularensis FSC198	4200681
YP_667158.1	CDS	FTF1043	NC_008245.1	1054202	1055014	D	Similar to O32766 Macrophage infectivity potentiator from Legionella hackeliae (249 aa). FASTA: opt: 235 Z-score: 273.3 E(): 2.5e-07 Smith-Waterman score: 343; 27.599 identity in 279 aa overlap. ORF ftt1043; FKBP-type peptidyl-prolyl cis-trans isomerase family protein	1054202..1055014	Francisella tularensis subsp. tularensis FSC198	4200682
YP_667159.1	CDS	ispB	NC_008245.1	1055032	1056009	R	Similar to Q8EB79 Octaprenyl-diphosphate synthase from Shewanella oneidensis (323 aa). FASTA: opt: 1117 Z-score: 1360.2 E(): 7.1e-68 Smith-Waterman score: 1117; 53.704 identity in 324 aa overlap.; octaprenyl-diphosphate synthase	complement(1055032..1056009)	Francisella tularensis subsp. tularensis FSC198	4199299
YP_667160.1	CDS	FTF1045c	NC_008245.1	1056099	1056530	R	ORF ftt1045c; hypothetical protein	complement(1056099..1056530)	Francisella tularensis subsp. tularensis FSC198	4200683
YP_667161.1	CDS	FTF1046c	NC_008245.1	1056611	1057234	R	ORF ftt1046c; hypothetical protein	complement(1056611..1057234)	Francisella tularensis subsp. tularensis FSC198	4200684
YP_667162.1	CDS	FTF1047c	NC_008245.1	1057906	1058268	R	ORF ftt1047c; hypothetical protein	complement(1057906..1058268)	Francisella tularensis subsp. tularensis FSC198	4200685
YP_667163.1	CDS	FTF1048c	NC_008245.1	1058320	1058886	R	ORF ftt1048c; hypothetical protein	complement(1058320..1058886)	Francisella tularensis subsp. tularensis FSC198	4200686
YP_667164.1	CDS	cysN	NC_008245.1	1059932	1061344	R	Similar to CYSN_VIBPA (Q87SX9) Sulfate adenylyltransferase subunit 1 from Vibrio parahaemolyticus (476 aa). FASTA: opt: 1823 Z-score: 2170.8 E(): 5e-113 Smith-Waterman score: 1823; 59.488 identity in 469 aa overlap.; sulfate adenylyltransferase	complement(1059932..1061344)	Francisella tularensis subsp. tularensis FSC198	4199522
YP_667165.1	CDS	FTF1051c	NC_008245.1	1061783	1061947	R	ORF ftt1051c; hypothetical protein	complement(1061783..1061947)	Francisella tularensis subsp. tularensis FSC198	4199801
YP_667166.1	CDS	FTF1052c	NC_008245.1	1062407	1062613	R	ORF ftt1052c; hypothetical protein	complement(1062407..1062613)	Francisella tularensis subsp. tularensis FSC198	4199802
YP_667167.1	CDS	rimI	NC_008245.1	1064341	1064829	R	Similar to RIMI_ECOLI (P09453) Ribosomal-protein-alanine acetyltransferase (148 aa). FASTA: opt: 237 Z-score: 305.5 E(): 4e-09 Smith-Waterman score: 237; 36.585 identity in 123 aa overlap.; ribosomal-protein-alanine acetyltransferase	complement(1064341..1064829)	Francisella tularensis subsp. tularensis FSC198	4199218
YP_667168.1	CDS	FTF1055c	NC_008245.1	1064807	1065232	R	ORF ftt1055c; hypothetical protein	complement(1064807..1065232)	Francisella tularensis subsp. tularensis FSC198	4199804
YP_667169.1	CDS	rluB	NC_008245.1	1065232	1066047	R	Similar to Q8ZEG0 Ribosomal large subunit pseudouridine synthase B from Yersinia pestis (318 aa). FASTA: opt: 938 Z-score: 1164.9 E(): 5.4e-57 Smith-Waterman score: 938; 56.705identity in 261 aa overlap.; ribosomal large subunit pseudouridine synthase B	complement(1065232..1066047)	Francisella tularensis subsp. tularensis FSC198	4199221
YP_667170.1	CDS	FTF1057c	NC_008245.1	1066040	1066945	R	Similar to Q9KRM4 Fimbrial biogenesis and twitching motility protein, putative from Vibrio cholerae (237 aa). FASTA: opt: 249 Z-score: 293.4 E(): 1.9e-08 Smith-Waterman score: 249; 25.346 identity in 217 aa overlap. Tetratrico peptide repeat (TPR) containing protein. Shows a weak similarity to the lipoprotein pilF (Pseudomonas) that has an N-terminal type II (lipoprotein) signal sequence,followed by six tandem degenerated 34-amino acid repeats,which are involved in protein-protein interactions. ORF ftt1057c; Type IV pili lipoprotein	complement(1066040..1066945)	Francisella tularensis subsp. tularensis FSC198	4199805
YP_667171.1	CDS	FTF1058c	NC_008245.1	1066935	1068047	R	Similar to Y2A6_PSEAE (Q51385) Hypothetical protein PA3806 from Pseudomonas aeruginosa (379 aa). FASTA: opt: 1458 Z-score: 1752.5 E(): 1e-89 Smith-Waterman score: 1458; 60.434 identity in 369 aa overlap. ORF ftt1058c; radical SAM superfamily protein	complement(1066935..1068047)	Francisella tularensis subsp. tularensis FSC198	4199806
YP_667172.1	CDS	dnaB	NC_008245.1	1068078	1069475	R	Similar to DNAB_PASMU (Q9CNL6) Replicative DNA helicase from Pasteurella multocida (467 aa). FASTA: opt: 1484 Z-score: 1719.2 E(): 7.2e-88 Smith-Waterman score: 1484; 51.016 identity in 443 aa overlap.; replicative DNA helicase	complement(1068078..1069475)	Francisella tularensis subsp. tularensis FSC198	4199351
YP_667173.1	CDS	rplI	NC_008245.1	1069563	1070018	R	in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9	complement(1069563..1070018)	Francisella tularensis subsp. tularensis FSC198	4200779
YP_667174.1	CDS	rpsR	NC_008245.1	1070037	1070255	R	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18	complement(1070037..1070255)	Francisella tularensis subsp. tularensis FSC198	4198956
YP_667175.1	CDS	rpsF	NC_008245.1	1070271	1070606	R	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6	complement(1070271..1070606)	Francisella tularensis subsp. tularensis FSC198	4200338
YP_667176.1	CDS	hemF	NC_008245.1	1071284	1072210	D	catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase	1071284..1072210	Francisella tularensis subsp. tularensis FSC198	4200375
YP_667177.1	CDS	FTF1064	NC_008245.1	1072235	1072825	D	Shows weak similarity to histidine acid phosphatase family. ORF ftt1064; hypothetical protein	1072235..1072825	Francisella tularensis subsp. tularensis FSC198	4199807
YP_667178.1	CDS	isftu1	NC_008245.1	1073364	1074148	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(1073364..1073822,1073822..1074148))	Francisella tularensis subsp. tularensis FSC198	4199638
YP_667179.1	CDS	FTF1066c	NC_008245.1	1074317	1074691	R	ORF ftt1066c; hypothetical protein	complement(1074317..1074691)	Francisella tularensis subsp. tularensis FSC198	4199808
YP_667180.1	CDS	FTF1068c	NC_008245.1	1078007	1078585	R	ORF ftt1068c; hypothetical protein	complement(1078007..1078585)	Francisella tularensis subsp. tularensis FSC198	4199809
YP_667181.1	CDS	FTF1069c	NC_008245.1	1078674	1079579	R	ORF ftt1069c; hypothetical protein	complement(1078674..1079579)	Francisella tularensis subsp. tularensis FSC198	4199810
YP_667182.1	CDS	FTF1071c	NC_008245.1	1082848	1083354	R	Similar to Q82XK5 Putative antirestriction protein from Nitrosomonas europaea (171 aa). FASTA: opt: 426 Z-score: 519.1 E(): 5e-21 Smith-Waterman score: 426; 42.771 identity in 166 aa overlap. ORF ftt1071c; hypothetical protein	complement(1082848..1083354)	Francisella tularensis subsp. tularensis FSC198	4199812
YP_667183.1	CDS	FTF1072	NC_008245.1	1083998	1084627	D	ORF ftt1072; hypothetical protein	1083998..1084627	Francisella tularensis subsp. tularensis FSC198	4199813
YP_667184.1	CDS	FTF1073c	NC_008245.1	1084783	1085154	R	ORF ftt1073c; hypothetical protein	complement(1084783..1085154)	Francisella tularensis subsp. tularensis FSC198	4199814
YP_667185.1	CDS	isftu1	NC_008245.1	1085388	1086172	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(1085388..1085714,1085714..1086172)	Francisella tularensis subsp. tularensis FSC198	4199639
YP_667186.1	CDS	FTF1075	NC_008245.1	1087056	1087283	D	Similar to Y4MF_RHISN (P55565) Hypothetical transcriptional regulator y4mF from Rhizobium sp. (strain NGR234) (76 aa). FASTA: opt: 205 Z-score: 292.4 E(): 2.1e-08 Smith-Waterman score: 205; 47.059identity in 68 aa overlap. ORF ftt1075; transcriptional regulator	1087056..1087283	Francisella tularensis subsp. tularensis FSC198	4199815
YP_667187.1	CDS	hipA	NC_008245.1	1087268	1088542	D	Similar to Q82V03 Possible HipA protein from Nitrosomonas europaea (429 aa). FASTA: opt: 1021 Z-score: 1249.8 E(): 1e-61 Smith-Waterman score: 1021; 41.162 identity in 413 aa overlap.; transcriptional regulator	1087268..1088542	Francisella tularensis subsp. tularensis FSC198	4200194
YP_667188.1	CDS	FTF1077c	NC_008245.1	1088666	1089052	R	Putative pseudogene. Bases 3-128 similar to the same homolog as for next upstream ORF, FRPC_NEIMC (P55127) Iron-regulated protein frpC from Neisseria meningitidis (serogroup C) (1829 aa). FASTA: opt: 118 Z-score: 143.0 bits: 35.9 E(): 4.5 Smith-Waterman score: 120; 26.351 identity in 148 aa overlap (3-128:582-728). ORF ftt1077c; hypothetical protein	complement(1088666..1089052)	Francisella tularensis subsp. tularensis FSC198	4199816
YP_667189.1	CDS	FTF1078c	NC_008245.1	1089033	1089845	R	Similar to FRPC_NEIMC (P55127) Iron-regulated protein frpC from Neisseria meningitidis (serogroup C) (1829 aa). FASTA: opt: 567 Z-score: 644.8 E(): 5.1e-28 Smith-Waterman score: 567; 53.416identity in 161 aa overlap (103-260:414-574). Putative pseudogene. Bases 103-260 similar to the same homolog as for the next downstream ORF. ORF ftt1078c; hypothetical protein	complement(1089033..1089845)	Francisella tularensis subsp. tularensis FSC198	4199817
YP_667190.1	CDS	FTF1079c	NC_008245.1	1089860	1090120	R	ORF ftt1079c; hypothetical protein	complement(1089860..1090120)	Francisella tularensis subsp. tularensis FSC198	4199818
YP_667191.1	CDS	FTF1080c	NC_008245.1	1090137	1091015	R	ORF ftt1080c; hypothetical protein	complement(1090137..1091015)	Francisella tularensis subsp. tularensis FSC198	4199819
YP_667192.1	CDS	FTF1081c	NC_008245.1	1091015	1091818	R	ORF ftt1081c; hypothetical protein	complement(1091015..1091818)	Francisella tularensis subsp. tularensis FSC198	4199573
YP_667193.1	CDS	FTF1082	NC_008245.1	1092044	1092466	D	ORF ftt1082; hypothetical protein	1092044..1092466	Francisella tularensis subsp. tularensis FSC198	4199574
YP_667194.1	CDS	FTF1083c	NC_008245.1	1092482	1092739	R	ORF ftt1083c; hypothetical protein	complement(1092482..1092739)	Francisella tularensis subsp. tularensis FSC198	4199575
YP_667195.1	CDS	rdgC	NC_008245.1	1092744	1093604	R	Required for efficient pilin antigenic variation; recombination associated protein	complement(1092744..1093604)	Francisella tularensis subsp. tularensis FSC198	4200598
YP_667196.1	CDS	FTF1085	NC_008245.1	1093786	1094784	D	Similar to YM90_SHEON (Q8EES8) Hypothetical UPF0176 protein SO229 from Shewanella oneidensis (333 aa). FASTA: initn: 1561 init1: 1472 opt: 1479 Z-score: 1729.8 E(): 1.9e-88 Smith-Waterman score: 1479; 63.636identity in 330 aa overlap. ORF ftt1085; hypothetical protein	1093786..1094784	Francisella tularensis subsp. tularensis FSC198	4199576
YP_667197.1	CDS	FTF1086c	NC_008245.1	1094915	1095745	R	Similar to Q8EFU7 Conserved hypothetical protein from Shewanella oneidensis (279 aa). FASTA: 351 opt: 789 Z-score: 963.7 E(): 8.8e-46 Smith-Waterman score: 789; 45.290 identity in 276 aa overlap. ORF ftt1086c; hypothetical protein	complement(1094915..1095745)	Francisella tularensis subsp. tularensis FSC198	4199577
YP_667198.1	CDS	rep	NC_008245.1	1095801	1097816	R	Similar to REP_HAEIN (P44804) ATP-dependent DNA helicase rep from Haemophilus influenzae (670 aa). FASTA: opt: 2055 Z-score: 2350.5 E(): 5e-123 Smith-Waterman score: 2055; 47.806 identity in 661 aa overlap.; ATP-dependent DNA helicase	complement(1095801..1097816)	Francisella tularensis subsp. tularensis FSC198	4200610
YP_667199.1	CDS	FTF1088c	NC_008245.1	1097810	1098556	R	ORF ftt1088c; hypothetical protein	complement(1097810..1098556)	Francisella tularensis subsp. tularensis FSC198	4199578
YP_667200.1	CDS	FTF1089	NC_008245.1	1099164	1099685	D	Similar to Q8EW31 Hypothetical protein from Mycoplasma penetrans (194 aa). FASTA: opt: 235 Z-score: 294.7 E(): 1.6e-08 Smith-Waterman score: 235; 31.515 identity in 165 aa overlap. ORF ftt1089; isochorismatase hydrolase family protein	1099164..1099685	Francisella tularensis subsp. tularensis FSC198	4199579
YP_667201.1	CDS	FTF1090	NC_008245.1	1099682	1100359	D	Similar to Q8A546 Putative membrane transporter involved in nicotinamide mononucleotide transport from Bacteroides thetaiotaomicron (188 aa). FASTA: opt: 285 Z-score: 336.8 E(): 7.2e-11 Smith-Waterman score: 302; 29.592 identity in 196 aa overlap. ORF ftt1090; hypothetical protein	1099682..1100359	Francisella tularensis subsp. tularensis FSC198	4199580
YP_667202.1	CDS	FTF1091	NC_008245.1	1100372	1100860	D	Similar to Q9AD62 Putative hydrolase (193 aa). FASTA: opt: 251 Z-score: 311.7 E(): 1.8e-09 Smith-Waterman score: 251; 32.075identity in 159 aa overlap. ORF ftt1091; isochorismatase hydrolase family protein	1100372..1100860	Francisella tularensis subsp. tularensis FSC198	4199581
YP_667203.1	CDS	FTF1092c	NC_008245.1	1101017	1101475	R	ORF ftt1092c; hypothetical protein	complement(1101017..1101475)	Francisella tularensis subsp. tularensis FSC198	4199582
YP_667204.1	CDS	talA	NC_008245.1	1101498	1102463	R	Similar to Q8EBH2 Transaldolase from Shewanella oneidensis (318 aa). FASTA: opt: 1030 Z-score: 1249.3 E(): 1.1e-61 Smith-Waterman score: 1030; 50.938 identity in 320 aa overlap.; transaldolase B	complement(1101498..1102463)	Francisella tularensis subsp. tularensis FSC198	4199095
YP_667205.1	CDS	FTF1094c	NC_008245.1	1102597	1104012	R	Similar to Q83DX0 Cytosol aminopeptidase family protein from Coxiella burnetii (458 aa). FASTA: opt: 1273 Z-score: 1536.1 E(): 1.1e-77 Smith-Waterman score: 1273; 41.830 identity in 459 aa overlap. ORF ftt1094c; cytosol aminopeptidase	complement(1102597..1104012)	Francisella tularensis subsp. tularensis FSC198	4199583
YP_667206.1	CDS	FTF1095c	NC_008245.1	1103979	1105361	R	Similar to Q88DA4 Outer membrane efflux protein from Pseudomonas putida (strain KT2440) (477 aa). FASTA: opt: 405 Z-score: 484.1 E(): 4.5e-19 Smith-Waterman score: 405; 22.907 identity in 454 aa overlap. Not a membrane protein. ORF ftt1095c; hypothetical protein	complement(1103979..1105361)	Francisella tularensis subsp. tularensis FSC198	4199584
YP_667207.1	CDS	alaS	NC_008245.1	1105369	1107966	R	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase	complement(1105369..1107966)	Francisella tularensis subsp. tularensis FSC198	4199759
YP_667208.1	CDS	FTF1097	NC_008245.1	1108122	1108568	D	ORF ftt1097; hypothetical protein	1108122..1108568	Francisella tularensis subsp. tularensis FSC198	4199585
YP_667209.1	CDS	FTF1099c	NC_008245.1	1110657	1110992	R	ORF ftt1099c; hypothetical protein	complement(1110657..1110992)	Francisella tularensis subsp. tularensis FSC198	4199587
YP_667210.1	CDS	FTF1100	NC_008245.1	1111095	1111430	D	Similar to Q83DY7 Iojap-related protein from Coxiella burnetii (116 aa). FASTA: opt: 326 Z-score: 425.2 E(): 8.6e-16 Smith-Waterman score: 326; 41.509 identity in 106 aa overlap. ORF ftt1100; hypothetical protein	1111095..1111430	Francisella tularensis subsp. tularensis FSC198	4199588
YP_667211.1	CDS	FTF1103	NC_008245.1	1112915	1114012	D	Similar to Q8Z9P6 Putative exported protein from Salmonella typhi (281 aa). FASTA: opt: 392 Z-score: 435.6 E(): 2.3e-16 Smith-Waterman score: 392; 33.491 identity in 212 aa overlap. ORF ftt1103; lipoprotein	1112915..1114012	Francisella tularensis subsp. tularensis FSC198	4199590
YP_667212.1	CDS	msrA1	NC_008245.1	1115496	1116350	R	this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae; bifunctional methionine sulfoxide reductase B/A protein	complement(1115496..1116350)	Francisella tularensis subsp. tularensis FSC198	4200100
YP_667213.1	CDS	tspO	NC_008245.1	1116479	1116955	D	Similar to Q8TID9 Benzodiazepine receptor TspO from Methanosarcina acetivorans (160 aa). FASTA: opt: 417 Z-score: 464.9 E(): 5.3e-18 Smith-Waterman score: 417; 40.994 identity in 161 aa overlap.; tryptophan-rich sensory protein	1116479..1116955	Francisella tularensis subsp. tularensis FSC198	4198973
YP_667214.1	CDS	FTF1108	NC_008245.1	1119041	1119793	D	Similar to Q891T6 23S rRNA methyltransferase (EC 2.1.1.-) from Clostridium tetani (260 aa). FASTA: opt: 442 Z-score: 545.7 E(): 1.7e-22 Smith-Waterman score: 442; 34.091 identity in 264 aa overlap. ORF ftt1108; rRNA methyltransferase	1119041..1119793	Francisella tularensis subsp. tularensis FSC198	4199591
YP_667215.1	CDS	FTF1109	NC_008245.1	1119887	1120855	D	Similar to Q8U768 Choloylglycine hydrolase family protein from Agrobacterium tumefaciens (strain C58 / ATCC 33970) (355 aa). FASTA: opt: 362 Z-score: 436.7 E(): 2e-16 Smith-Waterman score: 424; 28.956 identity in 297 aa overlap. ORF ftt1109; choloylglycine hydrolase family protein	1119887..1120855	Francisella tularensis subsp. tularensis FSC198	4200211
YP_667216.1	CDS	FTF1110	NC_008245.1	1121020	1121373	D	ORF ftt1110; hypothetical protein	1121020..1121373	Francisella tularensis subsp. tularensis FSC198	4200212
YP_667217.1	CDS	isftu2	NC_008245.1	1121469	1122212	D	ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa).; transposase	1121469..1122212	Francisella tularensis subsp. tularensis FSC198	4199292
YP_667218.1	CDS	rpoH	NC_008245.1	1122260	1123138	R	binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32	complement(1122260..1123138)	Francisella tularensis subsp. tularensis FSC198	4200331
YP_667219.1	CDS	FTF1113c	NC_008245.1	1123162	1123692	R	ORF ftt1113c; hypothetical protein	complement(1123162..1123692)	Francisella tularensis subsp. tularensis FSC198	4200213
YP_667220.1	CDS	secF	NC_008245.1	1123724	1124668	R	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF	complement(1123724..1124668)	Francisella tularensis subsp. tularensis FSC198	4200738
YP_667221.1	CDS	secD	NC_008245.1	1124687	1126624	R	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD	complement(1124687..1126624)	Francisella tularensis subsp. tularensis FSC198	4200736
YP_667222.1	CDS	yajC	NC_008245.1	1126681	1127037	R	Similar to Q8XFR4 (Q8XFR4) Putative membrane protein (Preprotein translocase IISP family, membrane subunit) from Salmonella typhi (110 aa). FASTA: opt: 347 Z-score: 458.8 E(): 1.2e-17 Smith-Waterman score: 347; 47.664 identity in 107 aa overlap.; preprotein translocase family protein	complement(1126681..1127037)	Francisella tularensis subsp. tularensis FSC198	4200699
YP_667223.1	CDS	FTF1117c	NC_008245.1	1127591	1128163	R	Similar to Q9HZE2 Hypothetical protein PA3066 from Pseudomonas aeruginosa (190 aa). FASTA: opt: 359 Z-score: 477.3 E(): 1.1e-18 Smith-Waterman score: 359; 35.638 identity in 188 aa overlap. ORF ftt1117c; isochorismatase hydrolase family protein	complement(1127591..1128163)	Francisella tularensis subsp. tularensis FSC198	4200214
YP_667224.1	CDS	FTF1118c	NC_008245.1	1128175	1129050	R	Similar to Q9KKY7 Hypothetical protein VCA0963 from Vibrio cholerae (307 aa). FASTA: opt: 340 Z-score: 385.2 E(): 1.5e-13 Smith-Waterman score: 340; 22.603 identity in 292 aa overlap. ORF ftt1118c; hypothetical protein	complement(1128175..1129050)	Francisella tularensis subsp. tularensis FSC198	4200215
YP_667225.1	CDS	FTF1119	NC_008245.1	1129155	1130030	D	Similar to Q8D460 Transcriptional regulator from Vibrio vulnificus (296 aa). FASTA: opt: 459 Z-score: 575.9 E(): 3.5e-24 Smith-Waterman score: 459; 29.197 identity in 274 aa overlap. ORF ftt1119; LysR transcriptional regulator family protein	1129155..1130030	Francisella tularensis subsp. tularensis FSC198	4200216
YP_667226.1	CDS	tgt	NC_008245.1	1130037	1131140	R	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase	complement(1130037..1131140)	Francisella tularensis subsp. tularensis FSC198	4199138
YP_667227.1	CDS	FTF1122c	NC_008245.1	1132114	1132584	R	ORF ftt1122c; lipoprotein	complement(1132114..1132584)	Francisella tularensis subsp. tularensis FSC198	4200218
YP_667228.1	CDS	ygiH	NC_008245.1	1133166	1133780	D	Similar to Y647_YERPE (Q8ZI67) Hypothetical UPF0078 protein YPO0647/Y3532 (216 aa). FASTA: opt: 604 Z-score: 713.6 E(): 7.4e-32 Smith-Waterman score: 604; 48.500 identity in 200 aa overlap.; hypothetical protein	1133166..1133780	Francisella tularensis subsp. tularensis FSC198	4199101
YP_667229.1	CDS	metN	NC_008245.1	1133743	1134819	D	Similar to AAP15732 ATP-binding component of a transporter from Shigella flexneri (343 aa). FASTA: opt: 1070 Z-score: 1232.1 E(): 9.7e-61 Smith-Waterman score: 1070; 46.221 identity in 344 aa overlap.; D-methionine transport protein, ABC transporter,ATP-binding subunit	1133743..1134819	Francisella tularensis subsp. tularensis FSC198	4199840
YP_667230.1	CDS	metIQ	NC_008245.1	1134797	1136269	D	Similar to METQ_SALTI (Q8Z992) D-methionine-binding lipoprotein metQ [Precursor] from Salmonella typhi (271 aa). FASTA: opt: 815 Z-score: 926.6 E(): 1e-43 Smith-Waterman score: 815; 51.020identity in 245 aa overlap. The FASTA-hits do not include the first 220 aa. Probably two genes, metI and metQ, in other organisms.; D-methionine binding transport protein, ABC transporter, membrane and periplasmic protein	1134797..1136269	Francisella tularensis subsp. tularensis FSC198	4199838
YP_667231.1	CDS	FTF1126	NC_008245.1	1136340	1137551	D	Similar to Q83BG9 Tryptophan/tyrosine permease family protein from Coxiella burnetii (426 aa). FASTA: opt: 560 Z-score: 604.8 E(): 8.5e-26 Smith-Waterman score: 560; 27.750identity in 400 aa overlap. ORF ftt1126; aromatic amino acid HAAP transporter	1136340..1137551	Francisella tularensis subsp. tularensis FSC198	4200219
YP_667232.1	CDS	FTF1127	NC_008245.1	1137617	1138375	D	Similar to Q83F83 Rhodanese domain protein from Coxiella burnetii (124 aa). FASTA: opt: 447 Z-score: 559.4 E(): 2.9e-23 Smith-Waterman score: 447; 51.240 identity in 121 aa overlap. ORF ftt1127; rhodanese-like family protein	1137617..1138375	Francisella tularensis subsp. tularensis FSC198	4200220
YP_667233.1	CDS	ispF	NC_008245.1	1138388	1138867	D	catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	1138388..1138867	Francisella tularensis subsp. tularensis FSC198	4199302
YP_667234.1	CDS	FTF1129c	NC_008245.1	1138872	1140557	R	Similar to CPHA_ANAVA (O86109) Cyanophycin synthetase from Anabaena variabilis (901 aa). FASTA: opt: 2470 Z-score: 2850.7 E(): 6.8e-151 Smith-Waterman score: 2506; 46.787 identity in 887 aa overlap. Probable paralog of cphA since the protein sequences show considerable divergence and gene length differ. ORF ftt1129c; hypothetical protein	complement(1138872..1140557)	Francisella tularensis subsp. tularensis FSC198	4200221
YP_667235.1	CDS	cphA	NC_008245.1	1140583	1143405	R	catalyze the formation of cyanophycin which may act to store excess nitrogen; cyanophycin synthetase	complement(1140583..1143405)	Francisella tularensis subsp. tularensis FSC198	4200273
YP_667236.1	CDS	glpQ	NC_008245.1	1144261	1145013	R	Similar to Q83DQ4 Glycerophosphoryl diester phosphodiesterase,putative (250 aa). FASTA: opt: 306 Z-score: 366.0 E(): 1.7e-12 Smith-Waterman score: 306; 28.916identity in 249 aa overlap.; glycerophosphoryl diester phosphodiesterase	complement(1144261..1145013)	Francisella tularensis subsp. tularensis FSC198	4199797
YP_667237.1	CDS	pilB	NC_008245.1	1145172	1146950	D	Similar to O68431 Pilus assembly protein PilB from Pseudomonas syringae (pv. tomato) (575 aa). FASTA: opt: 1381 Z-score: 1521.6 E(): 7.3e-77 Smith-Waterman score: 1592; 44.597 identity in 583 aa overlap. PilB is required for pili assembly. Homologous to pilT but which has the opposite effect. Homologs exists in other systems.; Type IV pili nucleotide binding protein, ABC transporter ATP-binding protein	1145172..1146950	Francisella tularensis subsp. tularensis FSC198	4199729
YP_667238.1	CDS	pilC	NC_008245.1	1146965	1148194	D	Similar to Q888U1 Type IV pilus biogenesis protein PilC from Pseudomonas syringae (pv. tomato) (405 aa). FASTA: opt: 1017 Z-score: 1153.2 E(): 2.4e-56 Smith-Waterman score: 1017; 39.055identity in 402 aa overlap. Termed pilF in N. gonorrhoeae.; Type IV pili polytopic inner membrane protein	1146965..1148194	Francisella tularensis subsp. tularensis FSC198	4199730
YP_667239.1	CDS	FTF1136c	NC_008245.1	1149438	1149773	R	ORF ftt1136c; hypothetical protein	complement(1149438..1149773)	Francisella tularensis subsp. tularensis FSC198	4200224
YP_667240.1	CDS	FTF1137c	NC_008245.1	1149790	1150050	R	ORF ftt1137c; hypothetical protein	complement(1149790..1150050)	Francisella tularensis subsp. tularensis FSC198	4200225
YP_667241.1	CDS	hemH	NC_008245.1	1150184	1151185	D	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase	1150184..1151185	Francisella tularensis subsp. tularensis FSC198	4200376
YP_667242.1	CDS	FTF1140	NC_008245.1	1153402	1153599	D	ORF ftt1140; hypothetical protein	1153402..1153599	Francisella tularensis subsp. tularensis FSC198	4200226
YP_667243.1	CDS	isftu1	NC_008245.1	1153853	1154637	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(1153853..1154311,1154311..1154637))	Francisella tularensis subsp. tularensis FSC198	4199640
YP_667244.1	CDS	FTF1143	NC_008245.1	1154974	1155219	D	ORF ftt1143; hypothetical protein	1154974..1155219	Francisella tularensis subsp. tularensis FSC198	4200228
YP_667245.1	CDS	chaB	NC_008245.1	1156275	1156481	D	Similar to Q8XGJ2 Cation transport regulator ChaB from Salmonella typhi (76 aa). FASTA: opt: 267 Z-score: 394.9 E(): 4.2e-14 Smith-Waterman score: 267; 54.412 identity in 68 aa overlap.; cation transport regulator	1156275..1156481	Francisella tularensis subsp. tularensis FSC198	4200321
YP_667246.1	CDS	dfp	NC_008245.1	1157589	1158764	R	Similar to DFP_HAEIN (P44953) DNA/pantothenate metabolism flavoprotein homolog from Haemophilus influenzae (400 aa). FASTA: opt: 1012 Z-score: 1206.6 E(): 2.6e-59 Smith-Waterman score: 1012; 43.577identity in 397 aa overlap.; 4'-phosphopantothenoylcysteine decarboxylase	complement(1157589..1158764)	Francisella tularensis subsp. tularensis FSC198	4199347
YP_667247.1	CDS	yjhB	NC_008245.1	1158777	1159961	R	Similar to YJHB_ECOLI (P39352) Hypothetical metabolite transport protein yjhB from Escherichia coli (405 aa). FASTA: opt: 383 Z-score: 393.4 E(): 5.1e-14 Smith-Waterman score: 383; 26.425 identity in 386 aa overlap.; major facilitator transporter	complement(1158777..1159961)	Francisella tularensis subsp. tularensis FSC198	4199030
YP_667248.1	CDS	FTF1149c	NC_008245.1	1160037	1161545	R	Similar to Q8XT33 Probable amino-acid permease transmembrane from Ralstonia solanacearum (Pseudomonas solanacearum) (543 aa). FASTA: opt: 960 Z-score: 1077.6 E(): 3.9e-52 Smith-Waterman score: 969; 35.730 identity in 445 aa overlap. ORF ftt1149c; amino acid transporter family protein	complement(1160037..1161545)	Francisella tularensis subsp. tularensis FSC198	4199460
YP_667249.1	CDS	putA	NC_008245.1	1161705	1165778	R	proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase	complement(1161705..1165778)	Francisella tularensis subsp. tularensis FSC198	4199126
YP_667250.1	CDS	FTF1151c	NC_008245.1	1165786	1166073	R	Similar to Q87LM9 Conserved hypothetical protein from Vibrio parahaemolyticus (86 aa). FASTA: opt: 176 Z-score: 242.1 E(): 1.4e-05 Smith-Waterman score: 176; 32.857 identity in 70 aa overlap. ORF ftt1151c; hypothetical protein	complement(1165786..1166073)	Francisella tularensis subsp. tularensis FSC198	4199461
YP_667251.1	CDS	FTF1152	NC_008245.1	1166287	1166670	D	ORF ftt1152; hypothetical protein	1166287..1166670	Francisella tularensis subsp. tularensis FSC198	4199462
YP_667252.1	CDS	FTF1153c	NC_008245.1	1166737	1166961	R	ORF ftt1153c; hypothetical protein	complement(1166737..1166961)	Francisella tularensis subsp. tularensis FSC198	4199463
YP_667253.1	CDS	aroB	NC_008245.1	1167019	1168098	R	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase	complement(1167019..1168098)	Francisella tularensis subsp. tularensis FSC198	4199432
YP_667254.1	CDS	aroK	NC_008245.1	1168095	1168625	R	type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I	complement(1168095..1168625)	Francisella tularensis subsp. tularensis FSC198	4199438
YP_667255.1	CDS	pilQ	NC_008245.1	1168751	1170535	R	Similar to Q8EK21 Type IV pilus biogenesis protein PilQ from Shewanella oneidensis (684 aa). FASTA: opt: 1014 Z-score: 1145.2 E(): 6.8e-56 Smith-Waterman score: 1014; 31.658 identity in 597 aa overlap. The nearest gene neighbours show similarity to pilN, pilO and pilP. Also required for type II protein secretion.; Type IV pilin multimeric outer membrane protein	complement(1168751..1170535)	Francisella tularensis subsp. tularensis FSC198	4199732
YP_667256.1	CDS	FTF1157c	NC_008245.1	1170548	1171138	R	Similar to Q8DCM3 Tfp pilus assembly protein PilP from Vibrio vulnificus (170 aa). FASTA: opt: 176 Z-score: 222.1 E(): 0.00018 Smith-Waterman score: 176; 29.921 identity in 127 aa overlap. Weak similarity to the lipoprotein pilP, which appears to be required for stabilisation of pilQ multimer formation. The nearest gene neighbours show similarity to pilN, pilO and pilQ, which indicates that this protein could be pilP ORF ftt1157c; Type IV pili lipoprotein	complement(1170548..1171138)	Francisella tularensis subsp. tularensis FSC198	4199464
YP_667257.1	CDS	FTF1158c	NC_008245.1	1171144	1171740	R	Similar to Q8PH76 Fimbrial assembly membrane protein from Xanthomonas axonopodis (pv. citri) (221 aa). FASTA: opt: 144 Z-score: 177.4 E(): 0.055 Smith-Waterman score: 144; 25.946 identity in 185 aa overlap. Weak similarity to type IV pili glycosylation protein (pilO). The nearest gene neighbours show similarity to pilN, pilP and pilQ, which indicates that this protein could be pilO. PilO is required for glycosylation of Pseudomonas aeruginosa pilin. ORF ftt1158c; Type IV pili glycosylation protein	complement(1171144..1171740)	Francisella tularensis subsp. tularensis FSC198	4199465
YP_667258.1	CDS	FTF1159c	NC_008245.1	1171734	1172297	R	Similar to Q52540 Membrane protein PilN from Pseudomonas syringae (199 aa). FASTA: opt: 143 Z-score: 182.6 E(): 0.028 Smith-Waterman score: 143; 23.704 identity in 135 aa overlap. The nearest gene neighbours show similarity to pilO, pilP and pilQ, which indicates that this protein could be pilN. PilN is also required for type II protein secretion. ORF ftt1159c; Type IV pili associated protein	complement(1171734..1172297)	Francisella tularensis subsp. tularensis FSC198	4199466
YP_667259.1	CDS	FTF1160c	NC_008245.1	1172299	1173303	R	ORF ftt1160c; hypothetical protein	complement(1172299..1173303)	Francisella tularensis subsp. tularensis FSC198	4199467
YP_667260.1	CDS	adk	NC_008245.1	1173430	1174086	D	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase	1173430..1174086	Francisella tularensis subsp. tularensis FSC198	4199758
YP_667261.1	CDS	FTF1163c	NC_008245.1	1177427	1177843	R	ORF ftt1163c; hypothetical protein	complement(1177427..1177843)	Francisella tularensis subsp. tularensis FSC198	4199469
YP_667262.1	CDS	era	NC_008245.1	1177858	1178751	R	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era	complement(1177858..1178751)	Francisella tularensis subsp. tularensis FSC198	4199678
YP_667263.1	CDS	aspC2	NC_008245.1	1178865	1180058	R	Similar to Q83E19 Aspartate aminotransferase from Coxiella burnetii (394 aa). FASTA: opt: 1067 Z-score: 1292.7 E(): 4.1e-64 Smith-Waterman score: 1067; 41.645 identity in 389 aa overlap.; aspartate aminotransferase	complement(1178865..1180058)	Francisella tularensis subsp. tularensis FSC198	4199690
YP_667264.1	CDS	FTF1166c	NC_008245.1	1180068	1180874	R	Similar to Q8D5X6 Predicted glutamine amidotransferase from Vibrio vulnificus (253 aa). FASTA: opt: 654 Z-score: 813.9 E(): 1.9e-37 Smith-Waterman score: 654; 42.466identity in 219 aa overlap. ORF ftt1166c; glutamine amidotransferases class-II family protein	complement(1180068..1180874)	Francisella tularensis subsp. tularensis FSC198	4199470
YP_667265.1	CDS	FTF1167c	NC_008245.1	1180878	1181516	R	Similar to Q8EE04 (Q8EE04) Conserved hypothetical protein from Shewanella oneidensis (236 aa). FASTA: opt: 349 Z-score: 425.3 E(): 8.5e-16 Smith-Waterman score: 359; 32.273 identity in 220 aa overlap. ORF ftt1167c; glycoprotease family protein	complement(1180878..1181516)	Francisella tularensis subsp. tularensis FSC198	4199471
YP_667266.1	CDS	nagA	NC_008245.1	1181520	1182653	R	Similar to Q99VS2 NagA protein (Probable N-acetylglucosamine-6-phosphate deacetylase) from Staphylococcus aureus (393 aa). FASTA: opt: 1006 Z-score: 1213.0 E(): 1.1e-59 Smith-Waterman score: 1006; 43.523 identity in 386 aa overlap.; N-acetylglucosamine-6-phosphate deacetylase	complement(1181520..1182653)	Francisella tularensis subsp. tularensis FSC198	4200234
YP_667267.1	CDS	FTF1169	NC_008245.1	1182716	1183588	D	Similar to Q8EE00 GTP-binding protein (313 aa). FASTA: opt: 793 Z-score: 926.5 E(): 1e-43 Smith-Waterman score: 793; 44.218 identity in 294 aa overlap. ORF ftt1169; GTP-binding protein	1182716..1183588	Francisella tularensis subsp. tularensis FSC198	4199472
YP_667268.1	CDS	FTF1170	NC_008245.1	1183652	1185400	D	ORF ftt1170; lipoprotein	1183652..1185400	Francisella tularensis subsp. tularensis FSC198	4199473
YP_667269.1	CDS	hsdM	NC_008245.1	1185390	1186856	R	Similar to Q8RN13 HsdM from Campylobacter jejuni (494 aa). FASTA: opt: 2001 Z-score: 2374.3 E(): 2.3e-124 Smith-Waterman score: 2001; 59.719 identity in 499 aa overlap.; DNA-methyltransferase, type I restriction-modification enzyme subunit M	complement(1185390..1186856)	Francisella tularensis subsp. tularensis FSC198	4200202
YP_667270.1	CDS	csp	NC_008245.1	1186843	1187274	R	Similar to Q9HSS3 Cold shock protein from Halobacterium sp. (strain NRC-1 / ATCC 700922 / JCM 11081) (74 aa). FASTA: opt: 170 Z-score: 221.1 E(): 0.0002 Smith-Waterman score: 170; 40.323identity in 62 aa overlap. CDS is longer than FASTA matches. Homology is to first 70 aa of protein only and no matches found for 2nd half of CDS; cold shock protein (DNA-binding)	complement(1186843..1187274)	Francisella tularensis subsp. tularensis FSC198	4200278
YP_667271.1	CDS	FTF1174c	NC_008245.1	1188786	1188995	R	ORF ftt1174c; hypothetical protein	complement(1188786..1188995)	Francisella tularensis subsp. tularensis FSC198	4199474
YP_667272.1	CDS	FTF1175c	NC_008245.1	1189195	1189833	R	ORF ftt1175c; hypothetical protein	complement(1189195..1189833)	Francisella tularensis subsp. tularensis FSC198	4199475
YP_667273.1	CDS	FTF1177c	NC_008245.1	1192509	1193567	R	ORF ftt1177c; hypothetical protein	complement(1192509..1193567)	Francisella tularensis subsp. tularensis FSC198	4199476
YP_667274.1	CDS	FTF1178c	NC_008245.1	1193624	1193872	R	ORF ftt1178c; hypothetical protein	complement(1193624..1193872)	Francisella tularensis subsp. tularensis FSC198	4199477
YP_667275.1	CDS	bipA	NC_008245.1	1194292	1196109	D	Similar to Q9KNJ4 GTP-binding protein TypA from Vibrio cholerae (609 aa). FASTA: opt: 2972 Z-score: 3319.9 E(): 5e-177 Smith-Waterman score: 2972; 73.045identity in 601 aa overlap.; GTP binding translational elongation factor Tu and G family protein	1194292..1196109	Francisella tularensis subsp. tularensis FSC198	4200308
YP_667276.1	CDS	ggt	NC_008245.1	1197052	1198857	R	Similar to Q8EFL9 Gamma-glutamyltranspeptidase from Shewanella oneidensis (579 aa). FASTA: opt: 2002 Z-score: 2308.7 E(): 1.1e-120 Smith-Waterman score: 2002; 54.545 identity in 572 aa overlap.; gamma-glutamyltranspeptidase	complement(1197052..1198857)	Francisella tularensis subsp. tularensis FSC198	4199283
YP_667277.1	CDS	FTF1183c	NC_008245.1	1199909	1201114	R	Similar to YFCK_ECO57 (Q8XCQ7) Hypothetical protein yfcK from Escherichia coli (668 aa). FASTA: opt: 495 Z-score: 572.0 E(): 5.7e-24 Smith-Waterman score: 495; 28.087 identity in 413 aa overlap. ORF ftt1183c; lipoprotein	complement(1199909..1201114)	Francisella tularensis subsp. tularensis FSC198	4200250
YP_667278.1	CDS	FTF1184c	NC_008245.1	1201156	1201461	R	Similar to Y369_VIBVU (Q8DF55) Hypothetical protein VV10369 from Vibrio vulnificus (117 aa). FASTA: opt: 238 Z-score: 320.2 E(): 6.1e-10 Smith-Waterman score: 238; 41.304 identity in 92 aa overlap. ORF ftt1184c; hypothetical protein	complement(1201156..1201461)	Francisella tularensis subsp. tularensis FSC198	4200251
YP_667279.1	CDS	FTF1185c	NC_008245.1	1201461	1201892	R	Similar to Q8ZH13 Hypothetical protein YPO1102 from Yersinia pestis (144 aa). FASTA: opt: 463 Z-score: 623.4 E(): 7.9e-27 Smith-Waterman score: 463; 43.662 39dentity in 142 aa overlap. ORF ftt1185c; hypothetical protein	complement(1201461..1201892)	Francisella tularensis subsp. tularensis FSC198	4200252
YP_667280.1	CDS	smpB	NC_008245.1	1201967	1202440	D	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein	1201967..1202440	Francisella tularensis subsp. tularensis FSC198	4199076
YP_667281.1	CDS	FTF1187	NC_008245.1	1202441	1203196	D	TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase	1202441..1203196	Francisella tularensis subsp. tularensis FSC198	4200253
YP_667282.1	CDS	FTF1188	NC_008245.1	1203468	1204103	D	ORF ftt1188; hypothetical protein	1203468..1204103	Francisella tularensis subsp. tularensis FSC198	4200254
YP_667283.1	CDS	xseA	NC_008245.1	1205899	1207284	R	bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit	complement(1205899..1207284)	Francisella tularensis subsp. tularensis FSC198	4200695
YP_667284.1	CDS	FTF1191	NC_008245.1	1207437	1208597	D	Similar to Q8RFU4 N-acyl-L-amino acid amidohydrolase from Fusobacterium nucleatum (subsp. nucleatum) (393 aa). FASTA: opt: 945 Z-score: 1170.3 E(): 2.7e-57 Smith-Waterman score: 945; 38.259 identity in 379 aa overlap. ORF ftt1191; aminoacylase	1207437..1208597	Francisella tularensis subsp. tularensis FSC198	4200256
YP_667285.1	CDS	FTF1193c	NC_008245.1	1209880	1210398	R	Similar to Q8ZBY8 Hypothetical protein YPO3242 (Putative amidotransferase) from Yersinia pestis (257 aa). FASTA: opt: 251 Z-score: 317.2 E(): 8.9e-10 Smith-Waterman score: 251; 26.609 identity in 233 aa overlap. ORF ftt1193c; hypothetical protein	complement(1209880..1210398)	Francisella tularensis subsp. tularensis FSC198	4200258
YP_667286.1	CDS	FTF1194c	NC_008245.1	1210415	1211341	R	Similar to Q884M8 Conserved hypothetical protein from Pseudomonas syringae (pv. tomato) (319 aa). FASTA: opt: 460 Z-score: 588.5 E(): 6.9e-25 Smith-Waterman score: 460; 30.435identity in 322 aa overlap. Putative pseudogene (upstream sequence matches homologs). ORF ftt1194c; lipoprotein	complement(1210415..1211341)	Francisella tularensis subsp. tularensis FSC198	4200259
YP_667287.1	CDS	FTF1196c	NC_008245.1	1213016	1214299	R	Similar to Q9ZC87 Proline/betaine transporter (PROP7) from Rickettsia prowazekii (423 aa). FASTA: opt: 746 Z-score: 810.0 E(): 3.2e-37 Smith-Waterman score: 746; 31.450identity in 407 aa overlap. ORF ftt1196c; major facilitator transporter	complement(1213016..1214299)	Francisella tularensis subsp. tularensis FSC198	4200261
YP_667288.1	CDS	murI	NC_008245.1	1214384	1215181	R	Similar to MURI_NEIMC (Q9RMM3) Glutamate racemase (EC 5.1.1.3) from Neisseria meningitidis (serogroup C) (270 aa). FASTA: opt: 826 Z-score: 958.8 E(): 1.6e-45 Smith-Waterman score: 826; 48.473identity in 262 aa overlap.; glutamate racemase	complement(1214384..1215181)	Francisella tularensis subsp. tularensis FSC198	4200111
YP_667289.1	CDS	FTF1198c	NC_008245.1	1215181	1216011	R	ORF ftt1198c; hypothetical protein	complement(1215181..1216011)	Francisella tularensis subsp. tularensis FSC198	4200262
YP_667290.1	CDS	uvrB	NC_008245.1	1216015	1218021	R	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B	complement(1216015..1218021)	Francisella tularensis subsp. tularensis FSC198	4200134
YP_667291.1	CDS	sbcB	NC_008245.1	1218023	1219471	R	Similar to Q83BX4 Exodeoxyribonuclease I,putative from Coxiella burnetii (458 aa). FASTA: opt: 677 Z-score: 797.9 E(): 1.5e-36 Smith-Waterman score: 1190; 39.875 identity in 479 aa overlap.; exodeoxyribonuclease I	complement(1218023..1219471)	Francisella tularensis subsp. tularensis FSC198	4198968
YP_667292.1	CDS	FTF1201c	NC_008245.1	1219605	1220327	R	Similar to Q9KKP5 Oxidoreductase,short-chain dehydrogenase/reductase family from Vibrio cholerae (239 aa). FASTA: opt: 1097 Z-score: 1344.5 E(): 5.4e-67 Smith-Waterman score: 1097; 72.458identity in 236 aa overlap. ORF ftt1201c; oxidoreductase, short-chain dehydrogenase family protein	complement(1219605..1220327)	Francisella tularensis subsp. tularensis FSC198	4200263
YP_667293.1	CDS	FTF1202	NC_008245.1	1220443	1221342	D	Similar to Q9KKP4 Transcriptional regulator, LysR family from Vibrio cholerae (301 aa). FASTA: opt: 661 Z-score: 794.3 E(): 2.4e-36 Smith-Waterman score: 661; 36.120identity in 299 aa overlap. ORF ftt1202; LysR family transcriptional regulator	1220443..1221342	Francisella tularensis subsp. tularensis FSC198	4200264
YP_667294.1	CDS	FTF1203c	NC_008245.1	1221353	1222258	R	ORF ftt1203c; hypothetical protein	complement(1221353..1222258)	Francisella tularensis subsp. tularensis FSC198	4200265
YP_667295.1	CDS	FTF1204c	NC_008245.1	1222245	1223327	R	ORF ftt1204c; hypothetical protein	complement(1222245..1223327)	Francisella tularensis subsp. tularensis FSC198	4200266
YP_667296.1	CDS	gidA	NC_008245.1	1223470	1225353	D	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA	1223470..1225353	Francisella tularensis subsp. tularensis FSC198	4199284
YP_667297.1	CDS	FTF1206	NC_008245.1	1225365	1225757	D	ORF ftt1206; hypothetical protein	1225365..1225757	Francisella tularensis subsp. tularensis FSC198	4200477
YP_667298.1	CDS	FTF1207	NC_008245.1	1225771	1227141	D	ORF ftt1207; hypothetical protein	1225771..1227141	Francisella tularensis subsp. tularensis FSC198	4200478
YP_667299.1	CDS	rpiA	NC_008245.1	1227143	1227817	D	Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A	1227143..1227817	Francisella tularensis subsp. tularensis FSC198	4200772
YP_667300.1	CDS	isftu1	NC_008245.1	1229891	1230675	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(1229891..1230349,1230349..1230675))	Francisella tularensis subsp. tularensis FSC198	4199641
YP_667301.1	CDS	FTF1211c	NC_008245.1	1230737	1231129	R	CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein ORF ftt1211c; hypothetical protein	complement(1230737..1231129)	Francisella tularensis subsp. tularensis FSC198	4200480
YP_667302.1	CDS	gloA	NC_008245.1	1231129	1231512	R	Similar to LGUL_VIBPA (P46235) Probable lactoylglutathione lyase from Vibrio parahaemolyticus (138 aa). FASTA: opt: 549 Z-score: 759.1 E(): 2.2e-34 Smith-Waterman score: 549; 64.516 identity in 124 aa overlap.; lactoylglutathione lyase	complement(1231129..1231512)	Francisella tularensis subsp. tularensis FSC198	4199791
YP_667303.1	CDS	FTF1213	NC_008245.1	1231628	1232341	D	Similar to YPDP_BACSU (P54163) Hypothetical protein ypdP from Bacillus subtilis (229 aa). FASTA: opt: 472 Z-score: 563.3 E(): 1.7e-23 Smith-Waterman score: 472; 40.435 identity in 230 aa overlap. ORF ftt1213; YhhQ family protein	1231628..1232341	Francisella tularensis subsp. tularensis FSC198	4200481
YP_667304.1	CDS	FTF1214c	NC_008245.1	1232595	1233386	R	Similar to Q8XN14 Hypothetical protein CPE0524 from Clostridium perfringens (264 aa). FASTA: opt: 486 Z-score: 584.5 E(): 1.1e-24 Smith-Waterman score: 486; 31.939 identity in 263 aa overlap. ORF ftt1214c; haloacid dehalogenase-like hydrolase family protein	complement(1232595..1233386)	Francisella tularensis subsp. tularensis FSC198	4200482
YP_667305.1	CDS	queA	NC_008245.1	1234021	1235043	R	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase	complement(1234021..1235043)	Francisella tularensis subsp. tularensis FSC198	4200594
YP_667306.1	CDS	FTF1216c	NC_008245.1	1235063	1235524	R	ORF ftt1216c; hypothetical protein	complement(1235063..1235524)	Francisella tularensis subsp. tularensis FSC198	4200483
YP_667307.1	CDS	visC	NC_008245.1	1235546	1236781	R	Similar to Q83F72 VisC protein from Coxiella burnetii (411 aa). FASTA: opt: 645 Z-score: 778.5 E(): 1.8e-35 Smith-Waterman score: 858; 37.192 identity in 406 aa overlap.; monooxygenase family protein	complement(1235546..1236781)	Francisella tularensis subsp. tularensis FSC198	4200140
YP_667308.1	CDS	ubiH	NC_008245.1	1236771	1237982	R	Similar to Q87UH4 2-octaprenyl-6-methoxyphenyl hydroxylase from Pseudomonas syringae (pv. tomato) (395 aa). FASTA: opt: 654 Z-score: 770.5 E(): 5e-35 Smith-Waterman score: 654; 32.143 identity in 392 aa overlap.; 2-octaprenyl-6-methoxyphenyl hydroxylase	complement(1236771..1237982)	Francisella tularensis subsp. tularensis FSC198	4198980
YP_667309.1	CDS	FTF1219c	NC_008245.1	1237991	1238527	R	Similar to YGA1_PSEPK (Q88CI0) Hypothetical UPF0149 protein PP5201 from Pseudomonas putida (strain KT2440) (184 aa). FASTA: opt: 269 Z-score: 349.3 E(): 1.4e-11 Smith-Waterman score: 269; 34.637identity in 179 aa overlap. ORF ftt1219c; hypothetical protein	complement(1237991..1238527)	Francisella tularensis subsp. tularensis FSC198	4200484
YP_667310.1	CDS	FTF1220	NC_008245.1	1238928	1239476	D	Similar to Q8ZM70 Putative ligase from Salmonella typhimurium (182 aa). FASTA: opt: 317 Z-score: 411.1 E(): 5.2e-15 Smith-Waterman score: 317; 32.727 identity in 165 aa overlap. ORF ftt1220; 5-formyltetrahydrofolate cyclo-ligase	1238928..1239476	Francisella tularensis subsp. tularensis FSC198	4200485
YP_667311.1	CDS	FTF1221	NC_008245.1	1239479	1239745	D	ORF ftt1221; hypothetical protein	1239479..1239745	Francisella tularensis subsp. tularensis FSC198	4200486
YP_667312.1	CDS	dedA2	NC_008245.1	1239752	1240378	D	Similar to Q89YU2 Conserved hypothetical protein,putative membrane protein from Bacteroides thetaiotaomicron (213 aa). FASTA: opt: 602 Z-score: 702.4 E(): 3.1e-31 Smith-Waterman score: 602; 42.857identity in 210 aa overlap.; DedA family protein	1239752..1240378	Francisella tularensis subsp. tularensis FSC198	4199533
YP_667313.1	CDS	dedA1	NC_008245.1	1240434	1241081	D	Similar to Q8R8Y8 Hypothetical protein DedA2 from Thermoanaerobacter tengcongensis (209 aa). FAST: opt: 674 Z-score: 828.7 E(): 2.9e-38 Smith-Waterman score: 674; 45.894 identity in 207 aa overlap.; DedA family protein	1240434..1241081	Francisella tularensis subsp. tularensis FSC198	4199532
YP_667314.1	CDS	recO	NC_008245.1	1241157	1241855	R	Similar to RECO_VIBVU (Q8DC74) DNA repair protein recO from Vibrio vulnificus (243 aa). FASTA: opt: 244 Z-score: 288.3 E(): 3.6e-08 Smith-Waterman score: 244; 29.130 identity in 230 aa overlap.; DNA repair protein recO	complement(1241157..1241855)	Francisella tularensis subsp. tularensis FSC198	4200606
YP_667315.1	CDS	FTF1225c	NC_008245.1	1241839	1242168	R	ORF ftt1225c; hypothetical protein	complement(1241839..1242168)	Francisella tularensis subsp. tularensis FSC198	4200487
YP_667316.1	CDS	iscS	NC_008245.1	1242161	1243336	R	Similar to ISCS_VIBCH (Q9KTY2) Cysteine desulfurase (EC 4.4.1.-) from Vibrio cholerae (404 aa). FASTA: opt: 1104 Z-score: 1336.0 E(): 1.6e-66 Smith-Waterman score: 1104; 45.812 identity in 382 aa overlap.; cysteine desulfarase	complement(1242161..1243336)	Francisella tularensis subsp. tularensis FSC198	4199613
YP_667317.1	CDS	rne	NC_008245.1	1243586	1246243	D	Similar to Q9KQG8 Ribonuclease E from Vibrio cholerae (1052 aa). FASTA: opt: 1928 Z-score: 1743.2 E(): 3.3e-89 Smith-Waterman score: 1943; 43.377 identity in 770 aa overlap.; ribonuclease E	1243586..1246243	Francisella tularensis subsp. tularensis FSC198	4199227
YP_667318.1	CDS	lgt	NC_008245.1	1246258	1247064	D	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase	1246258..1247064	Francisella tularensis subsp. tularensis FSC198	4199515
YP_667319.1	CDS	thyA	NC_008245.1	1247049	1247873	D	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase	1247049..1247873	Francisella tularensis subsp. tularensis FSC198	4199144
YP_667320.1	CDS	serA	NC_008245.1	1247876	1249120	D	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase	1247876..1249120	Francisella tularensis subsp. tularensis FSC198	4200741
YP_667321.1	CDS	mesJ	NC_008245.1	1249121	1250317	D	Similar to Q83BJ9 MesJ protein from Coxiella burnetii (449 aa). FASTA: opt: 639 Z-score: 733.1 E(): 6.1e-33 Smith-Waterman score: 726; 31.387identity in 411 aa overlap. Thought to be a cell cycle protein; PP-loop family protein	1249121..1250317	Francisella tularensis subsp. tularensis FSC198	4199665
YP_667322.1	CDS	isftu1	NC_008245.1	1250462	1251246	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(1250462..1250788,1250788..1251246)	Francisella tularensis subsp. tularensis FSC198	4199642
YP_667323.1	CDS	yjdL	NC_008245.1	1251320	1252648	R	Similar to YJDL_ECOLI (P39276) Hypothetical transporter yjdL from Escherichia coli (485 aa).FASTA: opt: 1064 Z-score: 1135.9 E(): 2.2e-55 Smith-Waterman score: 1064; 38.222 identity in 450 aa overlap.This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein; proton-dependent oligopeptide transport (POT) family protein	complement(1251320..1252648)	Francisella tularensis subsp. tularensis FSC198	4199111
YP_667324.1	CDS	FTF1234	NC_008245.1	1252899	1254044	D	Similar to Q8YIA2 Choloylglycine hydrolase (EC 3.5.1.24) from Brucella melitensis (367 aa). FASTA: opt: 387 Z-score: 460.1 E(): 9.7e-18 Smith-Waterman score: 574; 34.718 identity in 337 aa overlap. ORF ftt1234; choloylglycine hydrolase family protein	1252899..1254044	Francisella tularensis subsp. tularensis FSC198	4200488
YP_667325.1	CDS	lpcC	NC_008245.1	1254045	1255109	R	Similar to Q8FZH8 Lipopolysaccharide core biosynthesis mannosyltransferase LpcC from Brucella suis (354 aa). FASTA: opt: 825 Z-score: 1005.6 E(): 4e-48 Smith-Waterman score: 825; 38.352 identity in 352 aa overlap.; glycosyl transferases group 1 family protein	complement(1254045..1255109)	Francisella tularensis subsp. tularensis FSC198	4199564
YP_667326.1	CDS	FTF1236	NC_008245.1	1255279	1256367	D	ORF ftt1236; hypothetical protein	1255279..1256367	Francisella tularensis subsp. tularensis FSC198	4200489
YP_667327.1	CDS	FTF1237	NC_008245.1	1256375	1257265	D	Similar to Q8A3T1 Putative stress protein from Bacteroides thetaiotaomicron (309 aa). FASTA: opt: 308 Z-score: 375.2 E(): 5.2e-13 Smith-Waterman score: 348; 26.599 identity in 297 aa overlap. ORF ftt1237; glycosyl transferase family protein	1256375..1257265	Francisella tularensis subsp. tularensis FSC198	4200490
YP_667328.1	CDS	FTF1238c	NC_008245.1	1257291	1258622	R	ORF ftt1238c; hypothetical protein	complement(1257291..1258622)	Francisella tularensis subsp. tularensis FSC198	4200491
YP_667329.1	CDS	FTF1239	NC_008245.1	1258830	1260101	D	ORF ftt1239; hypothetical protein	1258830..1260101	Francisella tularensis subsp. tularensis FSC198	4200492
YP_667330.1	CDS	FTF1240c	NC_008245.1	1260116	1260664	R	Similar to YJGA_HAEIN (P45076) Hypothetical protein HI1151 from Haemophilus influenzae (178 aa). FASTA: opt: 359 Z-score: 390.6 E(): 7.3e-14 Smith-Waterman score: 359; 35.928 identity in 167 aa overlap. ORF ftt1240c; hypothetical protein	complement(1260116..1260664)	Francisella tularensis subsp. tularensis FSC198	4200493
YP_667331.1	CDS	glyA	NC_008245.1	1260768	1262021	D	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase	1260768..1262021	Francisella tularensis subsp. tularensis FSC198	4200288
YP_667332.1	CDS	FTF1242	NC_008245.1	1262303	1263565	D	ORF ftt1242; hypothetical protein	1262303..1263565	Francisella tularensis subsp. tularensis FSC198	4200494
YP_667333.1	CDS	mreA	NC_008245.1	1263447	1265300	R	Similar to EAA32028 Hypothetical protein from Neurospora crassa (567 aa). FASTA: opt: 643 Z-score: 759.7 E(): 2e-34 Smith-Waterman score: 793; 29.879 identity in 579 aa overlap.; FAD binding family protein	complement(1263447..1265300)	Francisella tularensis subsp. tularensis FSC198	4199854
YP_667334.1	CDS	yfiO	NC_008245.1	1265377	1266201	R	Similar to Q8XYX9 Probable transmembrane protein from Ralstonia solanacearum (Pseudomonas solanacearum) (289 aa). FASTA: opt: 563 Z-score: 689.8 E(): 1.6e-30 Smith-Waterman score: 563; 32.558 identity in 258 aa overlap.; lipoprotein	complement(1265377..1266201)	Francisella tularensis subsp. tularensis FSC198	4199100
YP_667335.1	CDS	rluD	NC_008245.1	1266290	1267288	D	Similar to Q87S65 Ribosomal large subunit pseudouridine from Vibrio parahaemolyticus (325 aa). FASTA: opt: 917 Z-score: 1118.2 E(): 2.2e-54 Smith-Waterman score: 917; 47.468 identity in 316 aa overlap.; ribosomal large subunit pseudouridine synthase D	1266290..1267288	Francisella tularensis subsp. tularensis FSC198	4199223
YP_667336.1	CDS	FTF1246	NC_008245.1	1267230	1268078	D	Similar to Q8EEM6 Bax protein, putative from Shewanella oneidensis (255 aa). FASTA: opt: 369 Z-score: 448.5 E(): 4.3e-17 Smith-Waterman score: 369; 31.081 identity in 222 aa overlap. ORF ftt1246; hypothetical protein	1267230..1268078	Francisella tularensis subsp. tularensis FSC198	4200495
YP_667337.1	CDS	FTF1247	NC_008245.1	1268153	1269253	D	Similar to Q9A5X9 ABC transporter,permease protein,putative from Caulobacter crescentus.(371 aa). FASTA: opt: 755 Z-score: 860.3 E(): 5e-40 Smith-Waterman score: 755; 36.095 identity in 338 aa overlap. ORF ftt1247; ABC transporter membrane protein	1268153..1269253	Francisella tularensis subsp. tularensis FSC198	4200496
YP_667338.1	CDS	FTF1248	NC_008245.1	1269268	1270029	D	Similar to Q83DK2 ABC transporter,ATP-binding protein from Coxiella burnetii (268 aa). FASTA: opt: 674 Z-score: 783.9 E(): 9e-36 Smith-Waterman score: 674; 46.188 identity in 223 aa overlap. ORF ftt1248; ABC transporter ATP-binding protein	1269268..1270029	Francisella tularensis subsp. tularensis FSC198	4200497
YP_667339.1	CDS	FTF1249	NC_008245.1	1270039	1270764	D	Similar to Q9HZ27 Hypothetical protein PA3213 from Pseudomonas aeruginosa (312 aa). FASTA: opt: 282 Z-score: 315.9 E(): 1.1e-09 Smith-Waterman score: 282; 23.661 identity in 224 aa overlap. The archetype (Rv0169) for mce related family proteins, was isolated as being necessary for colonization of, and survival within, the macrophage MEDLINE:93377076. ORF ftt1249; cell entry (mce) related family protein	1270039..1270764	Francisella tularensis subsp. tularensis FSC198	4200498
YP_667340.1	CDS	FTF1250	NC_008245.1	1270769	1271467	D	ORF ftt1250; hypothetical protein	1270769..1271467	Francisella tularensis subsp. tularensis FSC198	4200499
YP_667341.1	CDS	FTF1251c	NC_008245.1	1271457	1272143	R	Similar to Q8EDF8 Conserved hypothetical protein from Shewanella oneidensis (234 aa). FASTA: opt: 692 Z-score: 805.5 E(): 5.6e-37 Smith-Waterman score: 692; 44.828 identity in 232 aa overlap. ORF ftt1251c; hypothetical protein	complement(1271457..1272143)	Francisella tularensis subsp. tularensis FSC198	4200500
YP_667342.1	CDS	FTF1252	NC_008245.1	1272214	1272942	D	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE	1272214..1272942	Francisella tularensis subsp. tularensis FSC198	4200501
YP_667343.1	CDS	FTF1253	NC_008245.1	1273172	1274659	D	Similar to Q9KTB5 Proton/peptide symporter family protein from Vibrio cholerae (514 aa). FASTA: opt: 1234 Z-score: 1376.6 E(): 8.7e-69 Smith-Waterman score: 1245; 42.050identity in 478 aa overlap. ORF ftt1253; proton-dependent oligopeptide transport (POT) family protein	1273172..1274659	Francisella tularensis subsp. tularensis FSC198	4200502
YP_667344.1	CDS	fadD1	NC_008245.1	1274767	1276458	D	Similar to Q89UU0 Long-chain-fatty-acid-CoA ligase from Bradyrhizobium japonicum (561 aa). FASTA: opt: 1308 Z-score: 1621.3 E(): 2.1e-82 Smith-Waterman score: 1308; 38.324 identity in 561 aa overlap.; Acyl-CoA synthetase (long-chain-fatty-acid--CoA ligase)	1274767..1276458	Francisella tularensis subsp. tularensis FSC198	4199402
YP_667345.1	CDS	FTF1255c	NC_008245.1	1276446	1277294	R	Similar to Q8PAT1 Transcriptional regulator from Xanthomonas campestris (pv. campestris) (287 aa). FASTA: opt: 689 Z-score: 866.5 E(): 2.3e-40 Smith-Waterman score: 689; 37.354identity in 257 aa overlap. ORF ftt1255c; transcriptional regulator araC family protein	complement(1276446..1277294)	Francisella tularensis subsp. tularensis FSC198	4200503
YP_667346.1	CDS	emrB	NC_008245.1	1277438	1278967	D	Similar to Q83DE1 Drug resistance transporter,EmrB/QacA family from Coxiella burnetii (526 aa). FASTA: opt: 1037 Z-score: 1145.4 E(): 6.6e-56 Smith-Waterman score: 1037; 31.928 identity in 498 aa overlap.; major facilitator transporter	1277438..1278967	Francisella tularensis subsp. tularensis FSC198	4199674
YP_667347.1	CDS	emrA1	NC_008245.1	1278989	1280011	D	Similar to Q83DE0 Multidrug resistance protein from Coxiella burnetii (331 aa). FASTA: opt: 742 Z-score: 834.3 E(): 1.4e-38 Smith-Waterman score: 742; 37.695 identity in 321 aa overlap.; HlyD family secretion protein	1278989..1280011	Francisella tularensis subsp. tularensis FSC198	4199672
YP_667348.1	CDS	FTF1258	NC_008245.1	1280021	1281493	D	Similar to Q93NK3 Putative outer membrane protein from Pseudomonas syringae (pv. syringae) (475 aa). FASTA: opt: 594 Z-score: 697.2 E(): 6e-31 Smith-Waterman score: 594; 28.970 identity in 466 aa overlap. ORF ftt1258; outer membrane efflux protein	1280021..1281493	Francisella tularensis subsp. tularensis FSC198	4200504
YP_667349.1	CDS	nadE	NC_008245.1	1281622	1282371	D	Similar to NADE_MYCPN (P75216) Probable NH(3)-dependent NAD(+) synthetase Mycoplasma pneumoniae (248 aa). FASTA: opt: 601 Z-score: 760.1 E(): 1.9e-34 Smith-Waterman score: 601; 40.928identity in 237 aa overlap.; NH(3)-dependent NAD(+) synthetase	1281622..1282371	Francisella tularensis subsp. tularensis FSC198	4200232
YP_667350.1	CDS	FTF1260	NC_008245.1	1282475	1282897	D	ORF ftt1260; hypothetical protein	1282475..1282897	Francisella tularensis subsp. tularensis FSC198	4200505
YP_667351.1	CDS	isftu1	NC_008245.1	1283806	1284590	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(1283806..1284132,1284132..1284590)	Francisella tularensis subsp. tularensis FSC198	4199643
YP_667352.1	CDS	FTF1263c	NC_008245.1	1284882	1285877	R	Duplicate of FTF0354 and FTF0378. ORF ftt1263c; hypothetical protein	complement(1284882..1285877)	Francisella tularensis subsp. tularensis FSC198	4200507
YP_667353.1	CDS	isftu1	NC_008245.1	1286806	1287590	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(1286806..1287264,1287264..1287590))	Francisella tularensis subsp. tularensis FSC198	4199644
YP_667354.1	CDS	yhhW	NC_008245.1	1287614	1288327	R	Similar to YC10_PSEAE (Q9I4C8) Hypothetical protein PA1210 from Pseudomonas aeruginosa (232 aa). FASTA: opt: 602 Z-score: 765.5 E(): 9.5e-35 Smith-Waterman score: 602; 41.667 identity in 228 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein.; pirin family protein	complement(1287614..1288327)	Francisella tularensis subsp. tularensis FSC198	4199105
YP_667355.1	CDS	FTF1267	NC_008245.1	1288427	1289323	D	Similar to Q8E7Z8 Transcriptional regulator, LysR family from Shewanella oneidensis (289 aa). FASTA: opt: 561 Z-score: 683.5 E(): 3.5e-30 Smith-Waterman score: 561; 32.423identity in 293 aa overlap. ORF ftt1267; LysR transcriptional regulator family protein	1288427..1289323	Francisella tularensis subsp. tularensis FSC198	4200508
YP_667356.1	CDS	dnaJ1	NC_008245.1	1289337	1290461	R	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ	complement(1289337..1290461)	Francisella tularensis subsp. tularensis FSC198	4199354
YP_667357.1	CDS	dnaK	NC_008245.1	1290550	1292478	R	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK	complement(1290550..1292478)	Francisella tularensis subsp. tularensis FSC198	4199356
YP_667358.1	CDS	grpE	NC_008245.1	1292579	1293166	R	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE	complement(1292579..1293166)	Francisella tularensis subsp. tularensis FSC198	4200300
YP_667359.1	CDS	mltA	NC_008245.1	1293255	1294421	D	Similar to Q81ZZ6 Putative membrane-bound lytic murein transglycosylase A transmembrane protein from Nitrosomonas europaea (440 aa). FASTA: opt: 821 Z-score: 989.7 E(): 3.1e-47 Smith-Waterman score: 821; 39.769 identity in 347 aa overlap.; membrane-bound lytic murein transglycosylase A (MLT) family protein	1293255..1294421	Francisella tularensis subsp. tularensis FSC198	4199849
YP_667360.1	CDS	FTF1272	NC_008245.1	1294414	1295598	D	Similar to Q8KB91 Protoporphyrinogen oxidase,putative from Chlorobium tepidum (399 aa). FASTA: opt: 594 Z-score: 698.0 E(): 5.5e-31 Smith-Waterman score: 673; 31.552 identity in 393 aa overlap. ORF ftt1272; hypothetical protein	1294414..1295598	Francisella tularensis subsp. tularensis FSC198	4200509
YP_667361.2	CDS	rplM	NC_008245.1	1295737	1296165	D	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13	1295737..1296165	Francisella tularensis subsp. tularensis FSC198	4198989
YP_667362.2	CDS	rpsI	NC_008245.1	1296181	1296570	D	forms a direct contact with the tRNA during translation; 30S ribosomal protein S9	1296181..1296570	Francisella tularensis subsp. tularensis FSC198	4200341
YP_667363.1	CDS	mglA	NC_008245.1	1296630	1297247	D	Similar to O52734 Macrophage growth locus A from Francisella novicida strain U112 (205 aa). FASTA: opt: 1275 Z-score: 1587.7 E(): 1.5e-80 Smith-Waterman score: 1275; 99.512 identity in 205 aa overlap (1-205:1-205).; macrophage growth locus subunit A	1296630..1297247	Francisella tularensis subsp. tularensis FSC198	4199842
YP_667364.1	CDS	mglB	NC_008245.1	1297249	1297656	D	Identical to O52735 Macrophage growth locus B from Francisella novicida strain U112 (135 aa).; ClpXP protease specificity-enhancing factor	1297249..1297656	Francisella tularensis subsp. tularensis FSC198	4199843
YP_667365.1	CDS	FTF1277c	NC_008245.1	1297653	1298924	R	Similar to Q88EE1 Sodium-solute symporter, putative from Pseudomonas putida (strain KT2440) (459 aa). FASTA: opt: 279 Z-score: 311.8 E(): 1.8e-09 Smith-Waterman score: 300; 20.863identity in 417 aa overlap. ORF ftt1277c; Sodium-solute symporter family protein	complement(1297653..1298924)	Francisella tularensis subsp. tularensis FSC198	4200510
YP_667366.1	CDS	rnhB	NC_008245.1	1298917	1299480	R	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII	complement(1298917..1299480)	Francisella tularensis subsp. tularensis FSC198	4200767
YP_667367.1	CDS	yfhQ	NC_008245.1	1299482	1300225	R	Similar to Q8ZCR9 Putative SpoU-family rRNA methylase from Yersinia pestis (257 aa). FASTA: opt: 688 Z-score: 847.8 E(): 2.5e-39 Smith-Waterman score: 688; 47.755 identity in 245 aa overlap.; SpoU rRNA methylase family protein	complement(1299482..1300225)	Francisella tularensis subsp. tularensis FSC198	4199099
YP_667368.1	CDS	ptsN	NC_008245.1	1300218	1300673	R	Similar to Q88PA0 Phosphotransferase system,nitrogen regulatory IIA protein from Pseudomonas putida (strain KT2440) (154 aa). FASTA: opt: 239 Z-score: 318.2 E(): 7.8e-10 Smith-Waterman score: 239; 26.316identity in 152 aa overlap.; PEP-dependent sugar PTS system family protein	complement(1300218..1300673)	Francisella tularensis subsp. tularensis FSC198	4199949
YP_667369.1	CDS	yhbH	NC_008245.1	1300710	1301006	R	Similar to RP5M_PSEPK (P15592) Probable sigma(54) modulation protein from Pseudomonas putida (102 aa). FASTA: opt: 336 Z-score: 439.6 E(): 1.4e-16 Smith-Waterman score: 336; 54.839 identity in 93 aa overlap.; sigma-54 modulation protein	complement(1300710..1301006)	Francisella tularensis subsp. tularensis FSC198	4199103
YP_667370.1	CDS	FTF1282	NC_008245.1	1301125	1301370	D	ORF ftt1282; hypothetical protein	1301125..1301370	Francisella tularensis subsp. tularensis FSC198	4200511
YP_667371.1	CDS	trmE	NC_008245.1	1301376	1302728	D	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE	1301376..1302728	Francisella tularensis subsp. tularensis FSC198	4199864
YP_667372.1	CDS	FTF1284c	NC_008245.1	1302738	1302932	R	ORF ftt1284c; hypothetical protein	complement(1302738..1302932)	Francisella tularensis subsp. tularensis FSC198	4200512
YP_667373.1	CDS	FTF1285c	NC_008245.1	1302964	1303854	R	Similar to Q8D448 Transcriptional regulator from Vibrio vulnificus (303 aa). FASTA: opt: 372 Z-score: 436.1 E(): 2.1e-16 Smith-Waterman score: 372; 28.571 identity in 294 aa overlap. ORF ftt1285c; LysR transcriptional regulator family protein	complement(1302964..1303854)	Francisella tularensis subsp. tularensis FSC198	4200513
YP_667374.1	CDS	cbs	NC_008245.1	1305262	1306185	D	Similar to Q9BH24 Cystathionine beta-synthase 5 from Trypanosoma cruzi (384 aa). FASTA: opt: 540 Z-score: 651.0 E(): 2.3e-28 Smith-Waterman score: 542; 31.494 identity in 308 aa overlap.; cystathionine beta-synthase (cystein synthase)	1305262..1306185	Francisella tularensis subsp. tularensis FSC198	4200317
YP_667375.1	CDS	FTF1288	NC_008245.1	1306439	1307008	D	Similar to Q8Z651 Putative membrane protein from Salmonella typhi (204 aa). FASTA: opt: 462 Z-score: 553.9 E(): 5.9e-23 Smith-Waterman score: 462; 36.667 identity in 180 aa overlap. ORF ftt1288; hypothetical protein	1306439..1307008	Francisella tularensis subsp. tularensis FSC198	4200515
YP_667376.1	CDS	metG	NC_008245.1	1313866	1315890	D	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase	1313866..1315890	Francisella tularensis subsp. tularensis FSC198	4199837
YP_667377.1	CDS	FTF1291	NC_008245.1	1315856	1317130	D	Similar to EXUT_BACSU (O34456) Hexuronate transporter from Bacillus subtilis (422 aa). FASTA: opt: 655 Z-score: 716.7 E(): 5e-32 Smith-Waterman score: 659; 28.250 identity in 400 aa overlap. ORF ftt1291; major facilitator transporter	1315856..1317130	Francisella tularensis subsp. tularensis FSC198	4200517
YP_667378.1	CDS	FTF1292c	NC_008245.1	1317127	1317729	R	Similar to Q88YM1 Hypothetical protein from Lactobacillus plantarum (215 aa). FASTA: opt: 420 Z-score: 532.1 E(): 9.5e-22 Smith-Waterman score: 420; 35.025 identity in 197 aa overlap. ORF ftt1292c; hypothetical protein	complement(1317127..1317729)	Francisella tularensis subsp. tularensis FSC198	4200518
YP_667379.1	CDS	FTF1293c	NC_008245.1	1317779	1318393	R	Similar to Q9KSS8 Hypothetical protein VC1178 from Vibrio cholerae (206 aa). FASTA: opt: 558 Z-score: 715.6 E(): 5.8e-32 Smith-Waterman score: 558; 42.703 identity in 185 aa overlap. ORF ftt1293c; Sua5_yciO_yrdC family protein	complement(1317779..1318393)	Francisella tularensis subsp. tularensis FSC198	4200519
YP_667380.1	CDS	ispZ	NC_008245.1	1318454	1318984	D	Similar to ISPZ_RALSO (Q8XYL2) Probable intracellular septation protein from Ralstonia solanacearum (Pseudomonas solanacearum) (186 aa). FASTA: opt: 549 Z-score: 659.0 E(): 8.2e-29 Smith-Waterman score: 549; 38.150 identity in 173 aa overlap.; intracellular septation protein A family protein	1318454..1318984	Francisella tularensis subsp. tularensis FSC198	4199498
YP_667381.1	CDS	glk1	NC_008245.1	1319323	1320339	R	Similar to GLK_ANASP (P58616) Glucokinase from Anabaena sp. (strain PCC 7120) (342 aa). FASTA: opt: 735 Z-score: 904.6 E(): 1.7e-42 Smith-Waterman score: 735; 36.735 identity in 343 aa overlap.; glucose kinase	complement(1319323..1320339)	Francisella tularensis subsp. tularensis FSC198	4199785
YP_667382.1	CDS	ubiE	NC_008245.1	1320433	1321185	D	Similar to Q8D1I3 COQ5 methyltransferase from Yersinia pestis (251 aa). FASTA: opt: 1184 Z-score: 1440.7 E(): 2.4e-72 Smith-Waterman score: 1184; 70.800 identity in 250 aa overlap.; menaquinone biosynthesis methyltransferase	1320433..1321185	Francisella tularensis subsp. tularensis FSC198	4198978
YP_667383.1	CDS	FTF1297	NC_008245.1	1321169	1321774	D	ORF ftt1297; hypothetical protein	1321169..1321774	Francisella tularensis subsp. tularensis FSC198	4200520
YP_667384.1	CDS	ubiB	NC_008245.1	1321767	1323425	D	Similar to Q83A88 Ubiquinone biosynthesis protein AarF, putative from Coxiella burnetii (541 aa). FASTA: opt: 1682 Z-score: 2006.3 E(): 7.3e-104 Smith-Waterman score: 1682; 48.269 identity in 520 aa overlap. unrelated to the ABC transporter proteins.; 2-polyprenylphenol 6-hydroxylase	1321767..1323425	Francisella tularensis subsp. tularensis FSC198	4198977
YP_667385.1	CDS	hitA	NC_008245.1	1323431	1323769	D	Similar to Q82WM8 HIT (Histidine triad) family from Nitrosomonas europaea (116 aa). FASTA: opt: 424 Z-score: 574.5 E(): 4.1e-24 Smith-Waterman score: 424; 53.571 identity in 112 aa overlap.; histidine triad (HIT) family protein	1323431..1323769	Francisella tularensis subsp. tularensis FSC198	4200196
YP_667386.1	CDS	FTF1300c	NC_008245.1	1323786	1323917	R	ORF ftt1300c; hypothetical protein	complement(1323786..1323917)	Francisella tularensis subsp. tularensis FSC198	4200521
YP_667387.1	CDS	FTF1302	NC_008245.1	1324916	1325746	D	ORF ftt1302; hypothetical protein	1324916..1325746	Francisella tularensis subsp. tularensis FSC198	4200523
YP_667388.1	CDS	FTF1303c	NC_008245.1	1325748	1326623	R	ORF ftt1303c; hypothetical protein	complement(1325748..1326623)	Francisella tularensis subsp. tularensis FSC198	4200524
YP_667389.1	CDS	murB	NC_008245.1	1326702	1327550	R	Similar to MURB_THEMA (Q9X239) UDP-N-acetylenolpyruvoylglucosamine reductase from Thermotoga maritima (284 aa). FASTA: opt: 577 Z-score: 699.7 E(): 4.4e-31 Smith-Waterman score: 577; 39.273 identity in 275 aa overlap.; UDP-N-acetylenolpyruvoylglucosamine reductase	complement(1326702..1327550)	Francisella tularensis subsp. tularensis FSC198	4200105
YP_667390.1	CDS	murA	NC_008245.1	1327558	1328892	R	Similar to Q814X9 UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Bacillus cereus (strain ATCC 14579 / DSM 31) (434 aa). FASTA: opt: 697 Z-score: 859.3 E(): 5.6e-40 Smith-Waterman score: 765; 33.333 identity in 438 aa overlap.; UDP-N-acetylglucosamine 1-carboxyvinyltransferase	complement(1327558..1328892)	Francisella tularensis subsp. tularensis FSC198	4200104
YP_667391.1	CDS	engA	NC_008245.1	1328831	1330228	R	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA	complement(1328831..1330228)	Francisella tularensis subsp. tularensis FSC198	4199675
YP_667392.1	CDS	FTF1307c	NC_008245.1	1330444	1330980	R	ORF ftt1307c; hypothetical protein	complement(1330444..1330980)	Francisella tularensis subsp. tularensis FSC198	4200525
YP_667393.1	CDS	FTF1308c	NC_008245.1	1331025	1331633	R	ORF ftt1308c; hypothetical protein	complement(1331025..1331633)	Francisella tularensis subsp. tularensis FSC198	4200526
YP_667394.1	CDS	hflB	NC_008245.1	1332772	1334688	R	Similar to FTSH_ECO57 (Q8X9L0) Cell division protease ftsH from Escherichia coli O157:H7 (644 aa). FASTA: opt: 2569 Z-score: 2823.5 E(): 2.2e-149 Smith-Waterman score: 2569; 60.125 identity in 642 aa overlap.; ATP-dependent metalloprotease	complement(1332772..1334688)	Francisella tularensis subsp. tularensis FSC198	4200380
YP_667395.1	CDS	yieO	NC_008245.1	1334911	1336317	D	Similar to Q8UHQ9 MFS permease from Agrobacterium tumefaciens (strain C58 / ATCC 33970) (475 aa). FASTA: opt: 757 Z-score: 760.1 E(): 1.9e-34 Smith-Waterman score: 766; 32.735 identity in 446 aa overlap.; major facilitator transporter	1334911..1336317	Francisella tularensis subsp. tularensis FSC198	4199109
YP_667396.1	CDS	uvrA	NC_008245.1	1336323	1339145	R	Similar to UVRA_PSEAE (Q9HWG0) UvrABC system protein A (UvrA protein) from Pseudomonas aeruginosa (945 aa). FASTA: opt: 4062 Z-score: 4339.5 E():0 Smith-Waterman score: 4062; 63.800identity in 942 aa overlap.; DNA excision repair protein subunit A	complement(1336323..1339145)	Francisella tularensis subsp. tularensis FSC198	4198988
YP_667397.1	CDS	greA	NC_008245.1	1339184	1339666	R	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA	complement(1339184..1339666)	Francisella tularensis subsp. tularensis FSC198	4200297
YP_667398.1	CDS	FTF1314c	NC_008245.1	1339700	1340284	R	Similar to Q8EBJ4 Type IV pilus biogenesis protein (164 aa). FASTA: opt: 157 Z-score: 204.8 E(): 0.0016 Smith-Waterman score: 157; 27.607 identity in 163 aa overlap. The pili fiber building block protein has a highly distinct primary structure; a short positively charged leader sequence, and a highly conserved and highly hydrophobic amino-terminal domain which forms the core of the pilus fiber; A variety of studies suggest that the invariant glycine (G) at -1 is required for prepilin cleavage and assembly and that the glutamate (E) at + 5 is essential for assembly and efficient N-terminal methylation but not cleavage. The region near the carboxy terminus is often hydrophilic and is stabilized by one or two disulfide bridges that may be involved in recognition of receptors. The genes with these characteristics are usually termed pilA, pilE, pilV, pilW, pilX and FimU. (Mattick John S.. 'Type IV Pili and twitching motility'. Annu. Rev. Microbiol. 2002. 56:289-314.) This protein has all the characteristics described above, except the glutamate (E) at + 5, but shows a weak global homology. ORF ftt1314c; Type IV pili fiber building block protein	complement(1339700..1340284)	Francisella tularensis subsp. tularensis FSC198	4200527
YP_667399.1	CDS	pgi	NC_008245.1	1340285	1341907	R	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase	complement(1340285..1341907)	Francisella tularensis subsp. tularensis FSC198	4199242
YP_667400.1	CDS	FTF1316c	NC_008245.1	1341894	1342547	R	Similar to Q8R9T9 Thiamine pyrophosphokinase from Thermoanaerobacter tengcongensis (211 aa). FASTA: opt: 221 Z-score: 278.6 E(): 1.3e-07 Smith-Waterman score: 238; 25.943 identity in 212 aa overlap. ORF ftt1316c; thiamine pyrophospokinase	complement(1341894..1342547)	Francisella tularensis subsp. tularensis FSC198	4200528
YP_667401.1	CDS	guaB	NC_008245.1	1342613	1344073	R	Similar to Q88P22 Inosine-5-monophosphate dehydrogenase from Pseudomonas putida (strain KT2440) (489 aa). FASTA: opt: 2187 Z-score: 2403.4 E(): 5.6e-126 Smith-Waterman score: 2187; 68.033 identity in 488 aa overlap.; inosine-5-monophosphate dehydrogenase	complement(1342613..1344073)	Francisella tularensis subsp. tularensis FSC198	4200366
YP_667402.1	CDS	pepA	NC_008245.1	1344174	1345613	R	Similar to Q887M0 Cytosol aminopeptidase from Pseudomonas syringae (pv. tomato) (496 aa). FASTA: opt: 1161 Z-score: 1388.1 E(): 2e-69 Smith-Waterman score: 1165; 42.540 identity in 496 aa overlap.; cytosol aminopeptidase	complement(1344174..1345613)	Francisella tularensis subsp. tularensis FSC198	4199239
YP_667403.1	CDS	FTF1319	NC_008245.1	1345779	1346861	D	Similar to Q8EH61 Conserved hypothetical protein from Shewanella oneidensis (370 aa). FASTA: opt: 370 Z-score: 433.4 E(): 3e-16 Smith-Waterman score: 370; 21.508 identity in 358 aa overlap. ORF ftt1319; YjgP/YjgQ family permease	1345779..1346861	Francisella tularensis subsp. tularensis FSC198	4200529
YP_667404.1	CDS	FTF1320	NC_008245.1	1346861	1347922	D	Similar to Q8ZK26 Putative permease from Salmonella typhimurium (360 aa). FASTA: opt: 510 Z-score: 585.0 E(): 1.1e-24 Smith-Waterman score: 511; 27.147 identity in 361 aa overlap. ORF ftt1320; YjgP/YjgQ family permease	1346861..1347922	Francisella tularensis subsp. tularensis FSC198	4200530
YP_667405.1	CDS	FTF1321	NC_008245.1	1347930	1349183	D	Similar to Q83AI4 Peptidase, M16 family from Coxiella burnetii (459 aa). FASTA: opt: 868 Z-score: 1053.1 E(): 9.1e-51 Smith-Waterman score: 868; 34.158 identity in 404 aa overlap. ORF ftt1321; peptidase M16 family protein	1347930..1349183	Francisella tularensis subsp. tularensis FSC198	4200531
YP_667406.1	CDS	FTF1322	NC_008245.1	1349190	1350413	D	Similar to Q83AI5 Peptidase, M16 family from Coxiella burnetii (443 aa). FASTA: opt: 605 Z-score: 727.1 E(): 1.3e-32 Smith-Waterman score: 605; 28.607 identity in 402 aa overlap. ORF ftt1322; peptidase M16 family protein	1349190..1350413	Francisella tularensis subsp. tularensis FSC198	4200532
YP_667407.1	CDS	FTF1323	NC_008245.1	1350414	1350992	D	Similar to YHHF_HAEIN (P44869) Putative methylase HI0767 from Haemophilus influenzae (193 aa). FASTA: opt: 455 Z-score: 588.3 E(): 7e-25 Smith-Waterman score: 455; 42.697 identity in 178 aa overlap. ORF ftt1323; methylase	1350414..1350992	Francisella tularensis subsp. tularensis FSC198	4200533
YP_667408.1	CDS	FTF1324	NC_008245.1	1351026	1351676	D	Similar to Q9CM99 Hypothetical protein PM0935 from Pasteurella multocida (226 aa). FASTA: opt: 523 Z-score: 599.4 E(): 1.7e-25 Smith-Waterman score: 523; 39.151 identity in 212 aa overlap. ORF ftt1324; hypothetical protein	1351026..1351676	Francisella tularensis subsp. tularensis FSC198	4200552
YP_667409.1	CDS	miaE	NC_008245.1	1351729	1352340	R	Similar to Q88KV1 TRNA-(ms(2)io(6)a)-hydroxylase,putative from Pseudomonas putida (strain KT2440)(205 aa). FASTA: opt: 660 Z-score: 867.5 E(): 2e-40 Smith-Waterman score: 660; 50.777 identity in 193 aa overlap.; tRNA-(ms(2)io(6)a)-hydroxylase	complement(1351729..1352340)	Francisella tularensis subsp. tularensis FSC198	4199845
YP_667410.1	CDS	udp	NC_008245.1	1352456	1353259	D	Similar to Q9CKN8 Udp from Pasteurella multocida (252 aa). FASTA: opt: 817 Z-score: 1065.9 E(): 1.8e-51 Smith-Waterman score: 817; 48.760 identity in 242 aa overlap.; uridine phosphorylase	1352456..1353259	Francisella tularensis subsp. tularensis FSC198	4198982
YP_667411.1	CDS	cdd	NC_008245.1	1353280	1353681	D	Similar to Q8RCG7 Cytidine deaminase from Thermoanaerobacter tengcongensis (135 aa). FASTA: opt: 413 Z-score: 565.4 E(): 1.3e-23 Smith-Waterman score: 413; 52.273 identity in 132 aa overlap.; cytidine deaminase	1353280..1353681	Francisella tularensis subsp. tularensis FSC198	4200319
YP_667412.1	CDS	FTF1328c	NC_008245.1	1353879	1356908	R	Similar to Q8EDV0 Oxidoreductase,FAD-binding,putative from Shewanella oneidensis (1013 aa). FASTA: opt: 1758 Z-score: 1886.5 E(): 3.1e-97 Smith-Waterman score: 2679; 40.573 identity in 1013 aa overlap. Contains a frameshift after aa 89. ORF ftt1328c; hypothetical protein	complement(1353879..1356908)	Francisella tularensis subsp. tularensis FSC198	4200553
YP_667413.1	CDS	gpmI	NC_008245.1	1357128	1358666	D	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase	1357128..1358666	Francisella tularensis subsp. tularensis FSC198	4200295
YP_667414.1	CDS	serS	NC_008245.1	1358681	1359961	D	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase	1358681..1359961	Francisella tularensis subsp. tularensis FSC198	4200743
YP_667415.1	CDS	cscK	NC_008245.1	1360071	1360970	D	Similar to Q97IW7 Fructokinase from Clostridium acetobutylicum (288 aa). FASTA: opt: 932 Z-score: 1175.6 E(): 1.4e-57 Smith-Waterman score: 932; 47.603identity in 292 aa overlap.; fructokinase	1360071..1360970	Francisella tularensis subsp. tularensis FSC198	4200276
YP_667416.1	CDS	FTF1332	NC_008245.1	1361048	1362307	D	Similar to Q9X4C7 Repeat unit exporter from Escherichia coli (419 aa). FASTA: opt: 324 Z-score: 369.2 E(): 1.1e-12 Smith-Waterman score: 324; 22.604 identity in 407 aa overlap. ORF ftt1332; polysaccharide biosynthesis protein (export protein)	1361048..1362307	Francisella tularensis subsp. tularensis FSC198	4200554
YP_667417.1	CDS	FTF1333c	NC_008245.1	1362311	1362511	R	ORF ftt1333c; hypothetical protein	complement(1362311..1362511)	Francisella tularensis subsp. tularensis FSC198	4200555
YP_667418.1	CDS	FTF1334c	NC_008245.1	1362539	1363048	R	ORF ftt1334c; hypothetical protein	complement(1362539..1363048)	Francisella tularensis subsp. tularensis FSC198	4200556
YP_667419.1	CDS	cydD	NC_008245.1	1363425	1365206	D	in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein	1363425..1365206	Francisella tularensis subsp. tularensis FSC198	4200285
YP_667420.1	CDS	cydC	NC_008245.1	1365203	1366852	D	in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein	1365203..1366852	Francisella tularensis subsp. tularensis FSC198	4200284
YP_667421.1	CDS	dctA	NC_008245.1	1366854	1368104	R	Similar to DTA2_PSEAE (Q9I4F5) C4-dicarboxylate transport protein from Pseudomonas aeruginosa (436 aa). FASTA: opt: 1534 Z-score: 1703.1 E(): 5.7e-87 Smith-Waterman score: 1534; 55.206identity in 413 aa overlap.; C4-dicarboxylate transport protein	complement(1366854..1368104)	Francisella tularensis subsp. tularensis FSC198	4199528
YP_667422.1	CDS	FTF1338c	NC_008245.1	1368243	1368623	R	Similar to Q99WA6 SA0455 protein (Translation initiation inhibitor homologue) from Staphylococcus aureus (126 aa). FASTA: 452 opt: 452 Z-score: 597.7 E(): 2.1e-25 Smith-Waterman score: 452; 61.017 identity in 118 aa overlap. ORF ftt1338c; translation initiation inhibitor	complement(1368243..1368623)	Francisella tularensis subsp. tularensis FSC198	4200557
YP_667423.1	CDS	FTF1339c	NC_008245.1	1368623	1370167	R	Similar to Q87N13 Sulfate permease family protein from Vibrio parahaemolyticus (519 aa). FASTA: opt: 1333 Z-score: 1472.3 E(): 4.1e-74 Smith-Waterman score: 1602; 47.398 identity in 538 aa overlap. ORF ftt1339c; sulfate permease family protein	complement(1368623..1370167)	Francisella tularensis subsp. tularensis FSC198	4200558
YP_667424.1	CDS	isftu2	NC_008245.1	1370286	1371029	R	ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa).; transposase	complement(1370286..1371029)	Francisella tularensis subsp. tularensis FSC198	4199294
YP_667425.1	CDS	FTF1341	NC_008245.1	1371230	1371886	D	Similiar to CAD85637 (Q82TY8) Putative integral membrane transmembrane protein from Nitrosomonas europaea (221 aa). FASTA: 670 Z-score: 817.1 E(): 1.2e-37 50.226identity in 221 aa overlap ORF ftt1341; hypothetical protein	1371230..1371886	Francisella tularensis subsp. tularensis FSC198	4200559
YP_667426.1	CDS	FTF1342	NC_008245.1	1372000	1373055	D	Similar to Q08861 Gamma-aminobutyric acid-grated chloride- ion channel/receptor, zeta subunit, precusor from Lymnaea stagnalis (437 aa). FASTA: opt: 357 Z-score: 407.4 E(): 7.7e-15 Smith-Waterman score: 360; 23.510 identity in 302 aa overlap ORF ftt1342; hypothetical protein	1372000..1373055	Francisella tularensis subsp. tularensis FSC198	4200560
YP_667427.1	CDS	FTF1343c	NC_008245.1	1373350	1374159	R	ORF ftt1343c; hypothetical protein	complement(1373350..1374159)	Francisella tularensis subsp. tularensis FSC198	4200561
YP_667428.1	CDS	pdpA1	NC_008245.1	1379766	1382228	D	Similar to AAP58968.1 (Q7X3I9) PdpA from Francisella novicida (820 aa). BLAST Score = 1545 bits (4000), Expect = 0.0 Identities = 777/820 (94), Positives = 787/820 (95) Identical to FTF1699. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625; hypothetical protein	1379766..1382228	Francisella tularensis subsp. tularensis FSC198	4199230
YP_667429.1	CDS	pdpB1	NC_008245.1	1382233	1385514	D	Similar to AAP58967.1 (Q7X3J0) PdpB from Francisella novicida (1093 aa). BLAST Score = 1914 bits (4959), Expect = 0.0 Identities = 975/1093 (89),Positives = 988/1093 (90) Identical to FTF1700. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625; hypothetical protein	1382233..1385514	Francisella tularensis subsp. tularensis FSC198	4199232
YP_667430.1	CDS	FTF1346	NC_008245.1	1385504	1385881	D	Identical to FTF1701. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1346; hypothetical protein	1385504..1385881	Francisella tularensis subsp. tularensis FSC198	4200562
YP_667431.1	CDS	FTF1347	NC_008245.1	1385894	1386388	D	Similar to AAP58969.1 (Q7XI38) unknown protein from Francisella novicida (164 aa). BLAST Score = 305 bits (780), Expect = 2e-82 Identities = 163/164 (99),Positives = 163/164 (99) Identical to FTF1702. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1347; hypothetical protein	1385894..1386388	Francisella tularensis subsp. tularensis FSC198	4200563
YP_667432.1	CDS	FTF1348	NC_008245.1	1386393	1388123	D	1-213 aa similar to AAP58970.1 (Q7X3I7) unknown Francisella novicida (212 aa). BLAST Score 352 ,Expect = 1e-95 Identities = 177/209 (84), Positives = 189/209 (90). 330-580aa similar to AAP58971.1 (Q7X3I6) unknown protein from Francisella tularensis subsp. novicida (251 aa). BLAST Score = 483 bits (1244), Expect = e-135 Identities = 243/251 (96), Positives = 249/251 (99). Identical to FTF1703. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625. Protein fusion product of two hypothetical proteins in F. novicida. ORF ftt1348; hypothetical protein	1386393..1388123	Francisella tularensis subsp. tularensis FSC198	4200564
YP_667433.1	CDS	FTF1349	NC_008245.1	1388124	1388645	D	Similar to AAP58972.1 (Q7X3I5) unknown protein from Francisella novicida (173 aa). BLAST Score = 336, Expect = 1e-91 Identities = 170/173 (98), Positives = 171/173 (98) Identical to FTF1704. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1349; hypothetical protein	1388124..1388645	Francisella tularensis subsp. tularensis FSC198	4200565
YP_667434.1	CDS	FTF1350	NC_008245.1	1388658	1390088	D	Similar to AAP58973.1 (Q7X3I4) unknown protein from Francisella novicida (476 aa). BLAST Score = 864 bits (2233), Expect = 0.0 Identities = 433/476 (90),Positives = 437/476 (91) Identical to FTF1705. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1350; hypothetical protein	1388658..1390088	Francisella tularensis subsp. tularensis FSC198	4200566
YP_667435.1	CDS	FTF1351	NC_008245.1	1390101	1390724	D	Similar to AAP58974.1 (Q7X3I3) unknown protein from Francisella novicida (207 aa). BLAST Score = 391 bits (1005), Expect = e-108 Identities = 194/207 (93),Positives = 195/207 (94) Identical to FTF1706. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1351; hypothetical protein	1390101..1390724	Francisella tularensis subsp. tularensis FSC198	4200567
YP_667436.1	CDS	FTF1352	NC_008245.1	1390746	1391897	D	Similar to AAP58975.1 (Q7X3I2) unknown protein from Francisella novicida (262 aa), BLAST Score = 443 bits (1140), Expect = e-12 Identities = 229/262 (87),Positives = 235/262 (89) This protein is identical to FTF1707. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1352; hypothetical protein	1390746..1391897	Francisella tularensis subsp. tularensis FSC198	4200568
YP_667437.1	CDS	FTF1353	NC_008245.1	1391863	1392636	D	Similar to AAP58976.1 (Q7X3I1) unknown protein from Francisella novicida (257 aa). BLAST Score = 412, Expect = e-114 Identities = 213/257 (82), Positives = 213/257 (82) Identical to FTF1708. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625. ORF ftt1353; hypothetical protein	1391863..1392636	Francisella tularensis subsp. tularensis FSC198	4200569
YP_667438.1	CDS	pdpC1	NC_008245.1	1392676	1396662	D	Similar to AAP58966.1 PdpC from Francisella novicida (1218 aa). BLAST Score = 2172, Expect = 0.0 Identities = 1089/1220 (89), Positives = 1120/1220 (91),Gaps = 3/1220 (0) Identical to FTF1709. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625; hypothetical protein	1392676..1396662	Francisella tularensis subsp. tularensis FSC198	4199234
YP_667439.1	CDS	FTF1355	NC_008245.1	1396680	1397255	D	Similar to AAP58977.1 (Q7X3I0) unknown protein from Francisella novicida (188 aa). BLAST Score = 321, Expect = 3e-87 Identities = 156/174 (89), Positives = 162/174 (93) Identical to FTF1710. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1355; hypothetical protein	1396680..1397255	Francisella tularensis subsp. tularensis FSC198	4200570
YP_667440.1	CDS	iglD1	NC_008245.1	1397262	1398467	R	Similar to AAP58965.1 (Q7C3J6) IglD from Francisella novicida (398 aa). BLAST Score = 746, Expect = 0.0 Identities = 382/398 (95), Positives = 383/398 (96) Identical to FTF1711. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625; intracellular growth locus, subunit D	complement(1397262..1398467)	Francisella tularensis subsp. tularensis FSC198	4200659
YP_667441.1	CDS	iglC1	NC_008245.1	1398479	1399114	R	Similar to AAP58964.1 (Q7X3J5) IglC (23 kDa protein) from Francisella novicida (211 aa). BLAST Score = 405, Expect = e-112 Identities = 209/211 (99), Positives = 210/211 (99) Identical to FTF1712. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625; intracellular growth locus, subunit C	complement(1398479..1399114)	Francisella tularensis subsp. tularensis FSC198	4200657
YP_667442.1	CDS	iglB1	NC_008245.1	1399125	1400669	R	Similar to AAP58963.1 (Q7X3J4) IglB from Francisella novicida (514 aa). BLAST Score = 997, Expect = 0.0 Identities = 496/514 (96), Positives = 499/514 (97) Identical to FTF1713. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625; intracellular growth locus, subunit B	complement(1399125..1400669)	Francisella tularensis subsp. tularensis FSC198	4200655
YP_667443.1	CDS	iglA1	NC_008245.1	1400659	1401249	R	Similar to AAP58962.1 (Q7X3J5) IglA from Francisella novicida (184 aa). BLAST Score = 350, Expect = 6e-96 Identities = 181/184 (98), Positives = 181/184 (98) Identical to FTF1714. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625; intracellular growth locus, subunit A	complement(1400659..1401249)	Francisella tularensis subsp. tularensis FSC198	4200653
YP_667444.1	CDS	pdpD1	NC_008245.1	1401294	1404881	R	Similar to AAP58961.1 (Q7C3J6) PdpD from Francisella novicida (1245 aa). BLAST Score = 2194, Expect = 0.0 Identities = 1133/1245 (91), Positives = 1154/1245 (92), Gaps = 50/1245 (4) Identical to FTF1715. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625; hypothetical protein	complement(1401294..1404881)	Francisella tularensis subsp. tularensis FSC198	4199236
YP_667445.1	CDS	isftu1	NC_008245.1	1407237	1408021	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(1407237..1407695,1407695..1408021))	Francisella tularensis subsp. tularensis FSC198	4199646
YP_667446.1	CDS	fbaB	NC_008245.1	1410047	1411111	R	class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase	complement(1410047..1411111)	Francisella tularensis subsp. tularensis FSC198	4199405
YP_667447.1	CDS	pyk	NC_008245.1	1411124	1412560	R	Similar to AAO91275 (Q83AU7) Pyruvate kinase from Coxiella burnetii (477 aa). FASTA: opt: 1622 Z-score: 1687.6 E(): 3.8e-86 Smith-Waterman score: 1622; 53.249identity in 477 aa overlap domain, score 55.8,E-value 8.1e-14; pyruvate kinase	complement(1411124..1412560)	Francisella tularensis subsp. tularensis FSC198	4199128
YP_667448.1	CDS	pgk	NC_008245.1	1412576	1413754	R	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase	complement(1412576..1413754)	Francisella tularensis subsp. tularensis FSC198	4199243
YP_667449.1	CDS	gapA	NC_008245.1	1413773	1414819	R	Similar to Q8XKT9 Glyceraldehyde-3-phosphate dehydrogenase from Clostridium perfringens (332 aa). FASTA: opt: 1511 Z-score: 1671.9 E(): 2.8e-85 Smith-Waterman score: 1511; 71.341identity in 328 aa overlap; glyceraldehyde-3-phosphate dehydrogenase	complement(1413773..1414819)	Francisella tularensis subsp. tularensis FSC198	4199272
YP_667450.1	CDS	tktA	NC_008245.1	1414812	1416803	R	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase	complement(1414812..1416803)	Francisella tularensis subsp. tularensis FSC198	4199146
YP_667451.1	CDS	FTF1370	NC_008245.1	1416943	1417446	D	Similar to AAN42711 (Q83LI4) Orf, conserved hypothetical protein from Shigella flexneri (173 aa). FASTA: opt: 194 Z-score: 254.2 E(): 2.6e-06 Smith-Waterman score: 194; 26.708 identity in 161 aa overlap ORF ftt1370; hypothetical protein	1416943..1417446	Francisella tularensis subsp. tularensis FSC198	4199953
YP_667452.1	CDS	rpmF	NC_008245.1	1417490	1417672	D	some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32	1417490..1417672	Francisella tularensis subsp. tularensis FSC198	4199224
YP_667453.1	CDS	plsX	NC_008245.1	1417771	1418817	D	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX	1417771..1418817	Francisella tularensis subsp. tularensis FSC198	4199734
YP_667454.1	CDS	fabH	NC_008245.1	1418914	1419885	D	Similar to Q9JW56 Putative 3-oxoacyl-[acyl-carrier-protein] synthase III from Neisseria meningitidis (320 aa). FASTA: opt: 1148 Z-score: 1323.1 E(): 7.6e-66 Smith-Waterman score: 1148; 54.859 identity in 319 aa overlap; 3-oxoacyl-ACP synthase	1418914..1419885	Francisella tularensis subsp. tularensis FSC198	4199681
YP_667455.1	CDS	FTF1374	NC_008245.1	1419933	1420853	D	Similar to Q9CJS7 FabD from Pasteurella multocida (312 aa). FASTA: opt: 984 Z-score: 1099.0 E(): 2.3e-53 Smith-Waterman score: 984;50.163 identity in 307 aa overlap ORF ftt1374; malonyl CoA-acyl carrier protein transacylase	1419933..1420853	Francisella tularensis subsp. tularensis FSC198	4199954
YP_667456.1	CDS	fabG	NC_008245.1	1420867	1421610	D	Similar to Q9CJS6 FabG from Pasteurella multocida (242 aa). FASTA: opt: 1029 Z-score: 1192.2 E(): 1.5e-58 Smith-Waterman score: 1029; 66.667 identity in 240 aa overlap; 3-oxoacyl-(acyl-carrier-protein) reductase	1420867..1421610	Francisella tularensis subsp. tularensis FSC198	4199680
YP_667457.1	CDS	acpP	NC_008245.1	1421706	1421990	D	carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein	1421706..1421990	Francisella tularensis subsp. tularensis FSC198	4199754
YP_667458.1	CDS	fabF	NC_008245.1	1422070	1423329	D	Similar to Q8Y0J0 Probable 3-oxoacyl-[acyl-carrier-protein] synthase II from Ralstonia solanacearum (410 aa). FASTA: opt: 1679 Z-score: 1887.3 E(): 2.8e-97 Smith-Waterman score: 1679; 59.233 identity in 417 aa overlap; 3-oxoacyl-ACP synthase	1422070..1423329	Francisella tularensis subsp. tularensis FSC198	4199679
YP_667459.1	CDS	suhB	NC_008245.1	1426910	1427698	D	Similar to P22783 Inositol-1-monophosphatase from E. coli (267 aa). FASTA: opt: 630 Z-score: 759.0 E(): 2e-34 Smith-Waterman score: 656; 36.882identity in 263 aa overlap; inositol-1-monophosphatase	1426910..1427698	Francisella tularensis subsp. tularensis FSC198	4199091
YP_667460.1	CDS	sun	NC_008245.1	1427698	1428978	D	Similar to P44788 SUN protein (FMU protein) from Haemophilus influenzae (451 aa). FASTA: opt: 956 Z-score: 1079.4 E(): 2.9e-52 Smith-Waterman score: 956; 39.401 identity in 434 aa overlap; Sun protein	1427698..1428978	Francisella tularensis subsp. tularensis FSC198	4199092
YP_667461.1	CDS	FTF1384c	NC_008245.1	1428956	1429447	R	Similar to Q8D9X5 Probable acetyltransferase from Vibrio vulnificus (141 aa). FASTA: opt: 183 Z-score: 242.0 E(): 1.3e-05 Smith-Waterman score: 183; 27.132 identity in 129 aa overlap ORF ftt1384c; acetyltransferase	complement(1428956..1429447)	Francisella tularensis subsp. tularensis FSC198	4199959
YP_667462.1	CDS	FTF1385c	NC_008245.1	1429540	1429809	R	ORF ftt1385c; hypothetical protein	complement(1429540..1429809)	Francisella tularensis subsp. tularensis FSC198	4199960
YP_667463.1	CDS	isftu1	NC_008245.1	1429800	1430584	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(1429800..1430126,1430126..1430584)	Francisella tularensis subsp. tularensis FSC198	4199647
YP_667464.1	CDS	ligN	NC_008245.1	1431030	1433066	R	Similar to P43813 DNA ligase from Haemophilus influenzae (679 aa). FASTA: opt: 2154 Z-score: 2353.2 E(): 3.2e-123 Smith-Waterman score: 2154; 48.817 identity in 676 aa overlap; DNA ligase	complement(1431030..1433066)	Francisella tularensis subsp. tularensis FSC198	4199553
YP_667465.1	CDS	FTF1388	NC_008245.1	1433374	1434090	D	Similar to AAO81619 (Q833S4) Conserved domain protein from Enterococcus faecalis (281 aa). FASTA: opt: 171 Z-score: 214.0 E(): 0.00046 Smith-Waterman score: 194;26.337 identity in 243 aa overlap ORF ftt1388; hypothetical protein	1433374..1434090	Francisella tularensis subsp. tularensis FSC198	4199961
YP_667466.1	CDS	panB	NC_008245.1	1434092	1434886	D	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase	1434092..1434886	Francisella tularensis subsp. tularensis FSC198	4200090
YP_667467.1	CDS	panC	NC_008245.1	1434873	1435658	D	Similar to AAO89975 (Q83EA3) Pantoate-beta-alanine ligase from Coxiella burnetii (257 aa). FASTA: opt: 692 Z-score: 830.8 E(): 2e-38 Smith-Waterman score: 692; 40.927 identity in 259 aa overlap; pantoate-beta-alanine ligase	1434873..1435658	Francisella tularensis subsp. tularensis FSC198	4200091
YP_667468.1	CDS	panD	NC_008245.1	1435652	1435987	D	Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase	1435652..1435987	Francisella tularensis subsp. tularensis FSC198	4200092
YP_667469.1	CDS	FTF1392	NC_008245.1	1435991	1436761	D	type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase	1435991..1436761	Francisella tularensis subsp. tularensis FSC198	4199962
YP_667470.1	CDS	recD	NC_008245.1	1436770	1438638	R	Similar to Q9RPH5 RecD from Mycobacterium smegmatis (554 aa). FASTA: opt: 593 Z-score: 627.7 E(): 4.1e-27 Smith-Waterman score: 776; 32.510 identity in 486 aa overlap; exodeoxyribonuclease V subunit alpha	complement(1436770..1438638)	Francisella tularensis subsp. tularensis FSC198	4200602
YP_667471.1	CDS	recB	NC_008245.1	1438604	1442257	R	Similar to Q8EF45 Exodeoxyribonuclease V,beta subunit from Shewanella oneidensis (1259 aa). FASTA: opt: 742 Z-score: 770.7 E(): 4.5e-35 Smith-Waterman score: 1544; 30.448identity in 1317 aa overlap; exodeoxyribonuclease V subunit beta	complement(1438604..1442257)	Francisella tularensis subsp. tularensis FSC198	4200600
YP_667472.1	CDS	FTF1395c	NC_008245.1	1442329	1443759	R	Similar Q8A303 ATP-dependent DNA helicase from Bacteriodes thetaiotamicron (511 aa). FASTA: opt: 496 Z-score: 533.4 E(): 7.4e-22 Smith-Waterman score: 815; 32.200 identity in 500 aa overlap ORF ftt1395c; ATP-dependent DNA helicase	complement(1442329..1443759)	Francisella tularensis subsp. tularensis FSC198	4199963
YP_667473.1	CDS	FTF1396c	NC_008245.1	1443902	1444480	R	Similar to AAO81663 (Q833N3) Conserved hypothetical protein from Entercoccus faecalis (203 aa). FASTA: opt: 155 Z-score: 198.6 E(): 0.0033 Smith-Waterman score: 155; 25.850 identity in 147 aa overlap ORF ftt1396c; hypothetical protein	complement(1443902..1444480)	Francisella tularensis subsp. tularensis FSC198	4199964
YP_667474.1	CDS	recC	NC_008245.1	1444416	1447655	R	Similar to P44945 Exodeoxyribonuclease V gamma chain from Haemophilus influenzae (1121 aa). FASTA: opt: 1139 Z-score: 1214.3 E(): 8.7e-60 Smith-Waterman score: 1433; 28.344 identity in 1129 aa overlap; exodeoxyribonuclease V subunit gamma	complement(1444416..1447655)	Francisella tularensis subsp. tularensis FSC198	4200601
YP_667475.1	CDS	FTF1399	NC_008245.1	1449494	1450363	D	Similar to Q8KH10 Conserved hypothetical integral membrane (299 aa). FASTA: opt: 516 Z-score: 612.8 E(): 2.8e-26 Smith-Waterman score: 516; 29.818 identity in 275 aa overlap ORF ftt1399; hypothetical protein	1449494..1450363	Francisella tularensis subsp. tularensis FSC198	4199966
YP_667476.1	CDS	FTF1400c	NC_008245.1	1450377	1450763	R	ORF ftt1400c; hypothetical protein	complement(1450377..1450763)	Francisella tularensis subsp. tularensis FSC198	4199967
YP_667477.1	CDS	FTF1401	NC_008245.1	1450920	1451585	D	Similar to Q8HA35 Repressor (217 aa). FASTA: opt: 183 Z-score: 217.7 E(): 0.00028 Smith-Waterman score: 225; 29.167 identity in 216 aa overlap ORF ftt1401; prophage repressor protein	1450920..1451585	Francisella tularensis subsp. tularensis FSC198	4199968
YP_667478.1	CDS	FTF1402c	NC_008245.1	1452157	1453791	R	ORF ftt1402c; hypothetical protein	complement(1452157..1453791)	Francisella tularensis subsp. tularensis FSC198	4199761
YP_667479.1	CDS	feoA	NC_008245.1	1453808	1454032	R	Similar to P33649 Ferrous iron transport protein A from E. coli (75 aa). FASTA: opt: 148 Z-score: 228.5 E(): 7.1e-05 Smith-Waterman score: 148; 31.081 identity in 74 aa overlap; ferrous iron transport protein A	complement(1453808..1454032)	Francisella tularensis subsp. tularensis FSC198	4199408
YP_667480.1	CDS	FTF1404	NC_008245.1	1454141	1454848	D	Similar to Q8E9Y6 Cell division protein FtsN from Shewanella oneidensis (231 aa). FASTA: opt: 157 Z-score: 187.2 E(): 0.014 Smith-Waterman score: 180; 27.094 identity in 203 aa overlap ORF ftt1404; cell division protein	1454141..1454848	Francisella tularensis subsp. tularensis FSC198	4199762
YP_667481.1	CDS	gloB	NC_008245.1	1454926	1455684	R	Similar to Q47677 Probable hydroxyacylglutathione hydrolase from E. coli (251 aa). FASTA: opt: 426 Z-score: 519.2 E(): 4.6e-21 Smith-Waterman score: 426; 36.290 identity in 248 aa overlap; hydroxyacylglutathione hydrolase	complement(1454926..1455684)	Francisella tularensis subsp. tularensis FSC198	4199792
YP_667482.1	CDS	FTF1406c	NC_008245.1	1455698	1456855	R	ORF ftt1406c; hypothetical protein	complement(1455698..1456855)	Francisella tularensis subsp. tularensis FSC198	4199763
YP_667483.1	CDS	FTF1407c	NC_008245.1	1456852	1457937	R	ORF ftt1407c; hypothetical protein	complement(1456852..1457937)	Francisella tularensis subsp. tularensis FSC198	4199764
YP_667484.1	CDS	hemD	NC_008245.1	1457903	1458652	R	Similar to Q980U3 Uroporphyrinogen III synthase,putative from Sulfolobus solfataricus (237 aa). FASTA: opt: 171 Z-score: 213.0 E(): 0.00052 Smith-Waterman score: 171; 34.746 identity in 118 aa overlap; uroporphyrinogen III synthase	complement(1457903..1458652)	Francisella tularensis subsp. tularensis FSC198	4200373
YP_667485.1	CDS	FTF1409c	NC_008245.1	1458653	1459069	R	Similar to Q8PK22 Hypothetical protein from Xanthomonas axonopodis (145 aa). FASTA: opt: 415 Z-score: 523.5 E(): 2.6e-21 Smith-Waterman score: 415; 45.652 identity in 138 aa overlap ORF ftt1409c; hypothetical protein	complement(1458653..1459069)	Francisella tularensis subsp. tularensis FSC198	4199765
YP_667486.1	CDS	FTF1410	NC_008245.1	1459767	1460312	D	Similar to Q8XTB4 Probable transmembrane protein from Ralstonia solanacearum (184 aa). FASTA: opt: 443 Z-score: 558.2 E(): 3e-23 Smith-Waterman score: 443; 42.045 identity in 176 aa overlap ORF ftt1410; hypothetical protein	1459767..1460312	Francisella tularensis subsp. tularensis FSC198	4199766
YP_667487.1	CDS	proS	NC_008245.1	1462901	1464598	D	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase	1462901..1464598	Francisella tularensis subsp. tularensis FSC198	4199944
YP_667488.1	CDS	FTF1413	NC_008245.1	1464744	1465874	D	Similar to Q886Y5 Aminotransferase, classes I and II from Pseudomonas syringae (382 aa). FASTA: opt: 929 Z-score: 1036.9 E(): 6.6e-50 Smith-Waterman score: 929; 37.076 identity in 383 aa overlap ORF ftt1413; aminotransferase	1464744..1465874	Francisella tularensis subsp. tularensis FSC198	4199768
YP_667489.1	CDS	FTF1414	NC_008245.1	1465874	1466356	D	ORF ftt1414; hypothetical protein	1465874..1466356	Francisella tularensis subsp. tularensis FSC198	4199769
YP_667490.1	CDS	FTF1415	NC_008245.1	1466464	1467366	D	ORF ftt1415; hypothetical protein	1466464..1467366	Francisella tularensis subsp. tularensis FSC198	4199770
YP_667491.1	CDS	FTF1416c	NC_008245.1	1467418	1467831	R	ORF ftt1416c; lipoprotein	complement(1467418..1467831)	Francisella tularensis subsp. tularensis FSC198	4199771
YP_667492.1	CDS	FTF1417	NC_008245.1	1467985	1468770	D	Similar to Q8ZRJ8 Putative amidohydrolase from Salmonella typhimurium (255 aa). FASTA: opt: 723 Z-score: 882.8 E(): 2.6e-41 Smith-Waterman score: 723; 43.359 identity in 256 aa overlap ORF ftt1417; carbon-nitrogen hydrolase	1467985..1468770	Francisella tularensis subsp. tularensis FSC198	4199772
YP_667493.1	CDS	nusB	NC_008245.1	1468754	1469179	R	Similar to Q889Q5 N utilization substance protein B from Pseudomonas syringae (165 aa). FASTA: opt: 274 Z-score: 347.8 E(): 1.6e-11 Smith-Waterman score: 274; 32.847 identity in 137 aa overlap; N utilisation substance protein B	complement(1468754..1469179)	Francisella tularensis subsp. tularensis FSC198	4200758
YP_667494.1	CDS	FTF1419	NC_008245.1	1469366	1469692	D	ORF ftt1419; lipoprotein	1469366..1469692	Francisella tularensis subsp. tularensis FSC198	4199773
YP_667495.1	CDS	FTF1420	NC_008245.1	1469825	1470292	D	ORF ftt1420; hypothetical protein	1469825..1470292	Francisella tularensis subsp. tularensis FSC198	4199774
YP_667496.1	CDS	FTF1421	NC_008245.1	1470511	1470960	D	Similar to Q88E79 Conserved hypothetical protein from Pseudomonas putida (150 aa). FASTA: opt: 511 Z-score: 638.2 E(): 1.1e-27 Smith-Waterman score: 511; 46.809 identity in 141 aa overlap ORF ftt1421; hypothetical protein	1470511..1470960	Francisella tularensis subsp. tularensis FSC198	4199775
YP_667497.1	CDS	FTF1422	NC_008245.1	1471000	1471620	D	Similar to Q87UK0 Oxidoreductase, 2OG-Fe(II) oxygenase family (244 aa). FASTA: opt: 400 Z-score: 493.2 E(): 1.3e-19 33.163 identity in 196 aa overlap ORF ftt1422; oxidoreductase	1471000..1471620	Francisella tularensis subsp. tularensis FSC198	4199776
YP_667498.1	CDS	FTF1423c	NC_008245.1	1471613	1472362	R	Similar to Q8NQW1 Predicted permease from Corynebacterium glutamicum (250 aa). FASTA: opt: 472 Z-score: 553.4 E(): 5.6e-23 Smith-Waterman score: 472; 35.573 identity in 253 aa overlap. ORF ftt1423c; hypothetical protein	complement(1471613..1472362)	Francisella tularensis subsp. tularensis FSC198	4199777
YP_667499.1	CDS	FTF1424c	NC_008245.1	1472364	1473044	R	Similar to Q89VN8 Bll1007 protein from Bradyrhizobium japonicum (345 aa). FASTA: opt: 834 Z-score: 1018.3 E(): 7.2e-49 Smith-Waterman score: 834; 53.509 identity in 228 aa overlap ORF ftt1424c; hypothetical protein	complement(1472364..1473044)	Francisella tularensis subsp. tularensis FSC198	4199778
YP_667500.1	CDS	naoX	NC_008245.1	1473089	1474783	R	Similar to Q8XMF5 NADH oxidase from Clostridium perfringens (566 aa). FASTA: opt: 2055 Z-score: 2177.9 E(): 1.8e-113 57.117 identity in 548 aa overlap; NADH oxidase	complement(1473089..1474783)	Francisella tularensis subsp. tularensis FSC198	4200235
YP_667501.1	CDS	FTF1426c	NC_008245.1	1474805	1475323	R	Similar to Q8YQC8 Hypothetical protein from Anabaena sp. (177 aa). FASTA: opt: 465 Z-score: 572.2 E(): 5e-24 Smith-Waterman score: 465; 43.023 identity in 172 aa overlap ORF ftt1426c; hypothetical protein	complement(1474805..1475323)	Francisella tularensis subsp. tularensis FSC198	4199779
YP_667502.1	CDS	isftu1	NC_008245.1	1475863	1476647	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(1475863..1476189,1476189..1476647)	Francisella tularensis subsp. tularensis FSC198	4200173
YP_667503.1	CDS	FTF1428c	NC_008245.1	1476808	1477323	R	Similar to AAP10414 (Q81AS7) Acetyltransferase from Bacillus cereus (174 aa). FASTA: opt: 372 Z-score: 461.6 E(): 7.3e-18 Smith-Waterman score: 372; 40.341 identity in 176 aa overlap ORF ftt1428c; acetyltransferase	complement(1476808..1477323)	Francisella tularensis subsp. tularensis FSC198	4199780
YP_667504.1	CDS	rhtC	NC_008245.1	1478503	1479138	D	Similar Q8DDM9 to Putative threonine efflux protein from Vibrio vulnificus (223 aa). FASTA: opt: 310 Z-score: 386.3 E(): 1.1e-13 Smith-Waterman score: 310; 29.577 identity in 213 aa overlap; threonine efflux protein	1478503..1479138	Francisella tularensis subsp. tularensis FSC198	4199212
YP_667505.1	CDS	ppnK	NC_008245.1	1479135	1480025	R	Similar to Q89AR9 Putative inorganic polyphosphate/ATP-NAD kinase from Buchnera aphidicola (292 aa). FASTA: opt: 682 Z-score: 800.3 E(): 1e-36 Smith-Waterman score: 682; 38.776 identity in 294 aa overlap; inorganic phosphate/ATP-NAD kinase	complement(1479135..1480025)	Francisella tularensis subsp. tularensis FSC198	4199935
YP_667506.1	CDS	gtrB	NC_008245.1	1480214	1481158	D	Similar to Q55487 Putative glycosyl transferase from Synechocystis sp. (318 aa). FASTA: opt: 1079 Z-score: 1283.0 E(): 1.3e-63 Smith-Waterman score: 1079; 50.000 identity in 298 aa overlap; glycosyl transferase family protein	1480214..1481158	Francisella tularensis subsp. tularensis FSC198	4200364
YP_667507.1	CDS	yadH	NC_008245.1	1481162	1481941	R	Similar Q88LN3 ABC transporter,permease protein from Pseudomonas putida (259 aa). FASTA: opt: 890 Z-score: 979.2 E(): 1.1e-46 Smith-Waterman score: 890; 50.193 identity in 259 aa overlap; ABC transporter membrane protein	complement(1481162..1481941)	Francisella tularensis subsp. tularensis FSC198	4200697
YP_667508.1	CDS	yagD	NC_008245.1	1481950	1482873	R	Similar to Q9CNG2 YagD from Pasteurella multocida (312 aa). FASTA: opt: 1028 Z-score: 1082.3 E(): 2e-52 Smith-Waterman score: 1028; 50.662 identity in 302 aa overlap; ABC transporter ATP-binding protein	complement(1481950..1482873)	Francisella tularensis subsp. tularensis FSC198	4200698
YP_667509.1	CDS	isftu2	NC_008245.1	1483056	1483799	D	ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa).; transposase	1483056..1483799	Francisella tularensis subsp. tularensis FSC198	4199295
YP_667510.1	CDS	FTF1439c	NC_008245.1	1485078	1485845	R	Similar to Q87N28 Putative deoxyribonuclease from vibrio parahaemolyticus (255 aa). FASTA: opt: 787 Z-score: 917.1 E(): 3.1e-43 Smith-Waterman score: 787; 44.314 identity in 255 aa overlap ORF ftt1439c; deoxyribonuclease	complement(1485078..1485845)	Francisella tularensis subsp. tularensis FSC198	4200066
YP_667511.1	CDS	FTF1441	NC_008245.1	1487511	1487996	D	Similar to Q8YQ94 Hypothetical protein from Anabaena sp. (144 aa). FASTA: opt: 497 Z-score: 629.3 E(): 3.4e-27 Smith-Waterman score: 497; 54.610 identity in 141 aa overlap ORF ftt1441; hypothetical protein	1487511..1487996	Francisella tularensis subsp. tularensis FSC198	4200068
YP_667512.1	CDS	rpoA2	NC_008245.1	1488614	1489570	R	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha	complement(1488614..1489570)	Francisella tularensis subsp. tularensis FSC198	4200327
YP_667513.1	CDS	FTF1443c	NC_008245.1	1489658	1490560	R	Similar to Q87ZS7 ATPase, AAA family from Pseudomonas syringae (440 aa). FASTA: opt: 1018 Z-score: 1104.6 E(): 1.1e-53 Smith-Waterman score: 1096; 43.243 identity in 407 aa overlap ORF ftt1443c; recombination factor protein RarA	complement(1489658..1490560)	Francisella tularensis subsp. tularensis FSC198	4200069
YP_667514.1	CDS	ppx	NC_008245.1	1491128	1492063	R	Similar to P44828 Putative exopolyphosphatase from Pneumophilus influenzae (323 aa). FASTA: opt: 730 Z-score: 856.9 E(): 7.1e-40 Smith-Waterman score: 730; 41.275 identity in 298 aa overlap; exopolyphosphatase	complement(1491128..1492063)	Francisella tularensis subsp. tularensis FSC198	4199936
YP_667515.1	CDS	trxA1	NC_008245.1	1492252	1492575	D	Similar to Q9JYY9 Thioredoxin from Neisseria meningitidis (110 aa). FASTA: opt: 452 Z-score: 595.9 E(): 2.4e-25 Smith-Waterman score: 452; 62.000 identity in 100 aa overlap; thioredoxin	1492252..1492575	Francisella tularensis subsp. tularensis FSC198	4198969
YP_667516.1	CDS	rho	NC_008245.1	1492618	1493880	D	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho	1492618..1493880	Francisella tularensis subsp. tularensis FSC198	4199211
YP_667517.1	CDS	manB	NC_008245.1	1494992	1496476	R	Similar to Q8UCV4 Phosphomannomutase from Agrobacterium tumefaciens (506 aa). FASTA: opt: 1226 Z-score: 1345.0 E(): 4.6e-67 Smith-Waterman score: 1226; 41.127 identity in 479 aa overlap; phosphomannomutase	complement(1494992..1496476)	Francisella tularensis subsp. tularensis FSC198	4199659
YP_667518.1	CDS	manC	NC_008245.1	1496507	1497913	R	Similar to Q9ETR3 GDP-mannose pyrophosphorylase from Salmonella enterica (464 aa). FASTA: opt: 1571 Z-score: 1720.2 E(): 5.8e-88 Smith-Waterman score: 1571; 50.647 identity in 464 aa overlap; mannose-1-phosphate guanyltransferase	complement(1496507..1497913)	Francisella tularensis subsp. tularensis FSC198	4199660
YP_667519.1	CDS	wbtM	NC_008245.1	1498880	1499926	R	Similar to Q9RDY1 RmlB protein from Legionella pneumophila (351 aa). FASTA: opt: 1490 Z-score: 1729.8 E(): 1.7e-88 Smith-Waterman score: 1490; 64.392 identity in 337 aa overlap; dTDP-D-glucose 4,6-dehydratase	complement(1498880..1499926)	Francisella tularensis subsp. tularensis FSC198	4200687
YP_667520.1	CDS	wbtL	NC_008245.1	1500443	1501327	R	Similar to O66250 Glucose-1-phosphate-thymidylyltransferase from Actinobacillus actinomycetemcomitans (290 aa). FASTA: opt: 1336 Z-score: 1567.4 E(): 1.9e-79 Smith-Waterman score: 1336; 67.466 identity in 292 aa overlap; glucose-1-phosphate thymidylyltransferase	complement(1500443..1501327)	Francisella tularensis subsp. tularensis FSC198	4200152
YP_667521.1	CDS	wbtK	NC_008245.1	1501352	1502212	R	Similar to Q8ECG2 Glycosyl transferase, group 2 family protein from Shewanella oneidensis (298 aa). FASTA: opt: 724 Z-score: 845.9 E(): 2.9e-39 Smith-Waterman score: 724; 39.789 identity in 284 aa overlap; glycosyltransferase	complement(1501352..1502212)	Francisella tularensis subsp. tularensis FSC198	4200151
YP_667522.1	CDS	wzx	NC_008245.1	1502205	1503692	R	Similar to AAO39697(Q84DG4) O antigen flippase from E. coli (464 aa). FASTA: opt: 861 Z-score: 954.5 E(): 2.6e-45 Smith-Waterman score: 861; 31.343identity in 469 aa overlap; O-antigen flippase	complement(1502205..1503692)	Francisella tularensis subsp. tularensis FSC198	4200690
YP_667523.1	CDS	wbtJ	NC_008245.1	1503697	1504422	R	Similar to Q50721 Hypothetical protein Rv3404c precurser from Mycobacterium tuberculosis (234 aa). FASTA: opt: 562 Z-score: 656.5 E(): 1e-28 Smith-Waterman score: 562; 43.243 identity in 185 aa overlap; hypothetical protein	complement(1503697..1504422)	Francisella tularensis subsp. tularensis FSC198	4200150
YP_667524.1	CDS	wbtI	NC_008245.1	1504419	1505501	R	Similarity to Q97GL6 Sugar transaminase, involved in dTDP-4-amino-4,6-dideoxyglucose biosynthesis from Clostridium acetobutylicum (364 aa). FASTA: opt: 1344 Z-score: 1521.8 E(): 6.5e-77 Smith-Waterman score: 1344; 59.155 identity in 355 aa overlap; sugar transamine/perosamine synthetase	complement(1504419..1505501)	Francisella tularensis subsp. tularensis FSC198	4200149
YP_667525.1	CDS	wbtH	NC_008245.1	1505494	1507380	R	Similar to Q8GGB6 Asparagine synthase-like protein from Pseudomonas aeruginosa (627 aa). FASTA: opt: 1855 Z-score: 2052.2 E(): 1.9e-106 Smith-Waterman score: 1855; 46.022 identity in 641 aa overlap; asparagine synthase	complement(1505494..1507380)	Francisella tularensis subsp. tularensis FSC198	4200148
YP_667526.1	CDS	wbtG	NC_008245.1	1507380	1508480	R	Similar to Q8ECG6 Glycosyl transferase group 1 family protein from Shewanella oneidensis (373 aa). FASTA: opt: 531 Z-score: 625.5 E(): 5.5e-27 Smith-Waterman score: 531; 32.353 identity in 374 aa overlap; glycosyl transferase family protein	complement(1507380..1508480)	Francisella tularensis subsp. tularensis FSC198	4200147
YP_667527.1	CDS	wzy	NC_008245.1	1508477	1509706	R	membrane protein/O-antigen polymerase (personal communication from authors); membrane protein/O-antigen protein	complement(1508477..1509706)	Francisella tularensis subsp. tularensis FSC198	4200691
YP_667528.1	CDS	wbtF	NC_008245.1	1509723	1510694	R	Similar to Q8KN66 WbpP from Pseudomonas aeruginosa (341 aa). FASTA: opt: 1033 Z-score: 1225.7 E(): 2e-60 Smith-Waterman score: 1033; 51.562identity in 320 aa overlap; NAD dependent epimerase	complement(1509723..1510694)	Francisella tularensis subsp. tularensis FSC198	4200146
YP_667529.1	CDS	wbtE	NC_008245.1	1510694	1512004	R	Similar to Q8EMC3 Vi polysaccharide biosynthesis from Oceanobacillus iheyensis (437 aa). FASTA: opt: 1817 Z-score: 2048.6 E(): 2.9e-106 Smith-Waterman score: 1817; 59.268 identity in 437 aa overlap; UDP-glucose/GDP-mannose dehydrogenase	complement(1510694..1512004)	Francisella tularensis subsp. tularensis FSC198	4200145
YP_667530.1	CDS	wbtD	NC_008245.1	1512022	1513113	R	Similar to Q8EMF7 Galacturonosyl transferase from Oceanobacillus iheyensis (362 aa). FASTA: opt: 908 Z-score: 1050.2 E(): 1.2e-50 Smith-Waterman score: 908; 40.223 identity in 358 aa overlap; galacturonosyl transferase	complement(1512022..1513113)	Francisella tularensis subsp. tularensis FSC198	4200144
YP_667531.1	CDS	wbtC	NC_008245.1	1513103	1513894	R	Similar to Q9K6L4 UDP-glucose 4-epimerase from Bacillus halodurans (282 aa). FASTA: opt: 758 Z-score: 904.3 E(): 1.6e-42 Smith-Waterman score: 758; 45.455 identity in 264 aa overlap; UDP-glucose 4-epimerase	complement(1513103..1513894)	Francisella tularensis subsp. tularensis FSC198	4200143
YP_667532.1	CDS	wbtB	NC_008245.1	1513896	1514513	R	Similarity to Q9K6L3 Galactosyltransferase from Bacillus halodurans (207 aa). FASTA: opt: 902 Z-score: 1122.0 E(): 1.2e-54 Smith-Waterman score: 902; 66.667 identity in 195 aa overlap; galactosyl transferase	complement(1513896..1514513)	Francisella tularensis subsp. tularensis FSC198	4200142
YP_667533.1	CDS	wbtA	NC_008245.1	1514521	1516257	R	Similar to Q9S4V4 PglF from Campylobacter jejuni (590 aa). FASTA: opt: 1343 Z-score: 1435.9 E(): 3.9e-72 Smith-Waterman score: 1378; 43.543identity in 604 aa overlap; dTDP-glucose 4,6-dehydratase	complement(1514521..1516257)	Francisella tularensis subsp. tularensis FSC198	4200141
YP_667534.1	CDS	isftu2	NC_008245.1	1516359	1517102	R	ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa).; transposase	complement(1516359..1517102)	Francisella tularensis subsp. tularensis FSC198	4199296
YP_667535.1	CDS	nadB	NC_008245.1	1518207	1519694	R	Similar to Q8XQG4 L-aspartate oxidase 2 from Ralstonia solanacearum (536 aa). FASTA: opt: 1043 Z-score: 1161.3 E(): 7.8e-57 Smith-Waterman score: 1043; 38.008 identity in 492 aa overlap; L-aspartate oxidase	complement(1518207..1519694)	Francisella tularensis subsp. tularensis FSC198	4200230
YP_667536.1	CDS	nadC	NC_008245.1	1519697	1520560	R	Similar to Q8DC25 Nicotinate-nucleotide pyrophosphorylase from Vibrio vulnificus (295 aa). FASTA: opt: 888 Z-score: 999.5 E(): 8e-48 Smith-Waterman score: 888; 53.737 identity in 281 aa overlap; nicotinate-nucleotide pyrophosphorylase	complement(1519697..1520560)	Francisella tularensis subsp. tularensis FSC198	4200231
YP_667537.1	CDS	nadA	NC_008245.1	1520569	1521594	R	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase	complement(1520569..1521594)	Francisella tularensis subsp. tularensis FSC198	4200117
YP_667538.1	CDS	gmk	NC_008245.1	1521615	1522187	R	Essential for recycling GMP and indirectly, cGMP; guanylate kinase	complement(1521615..1522187)	Francisella tularensis subsp. tularensis FSC198	4200291
YP_667539.1	CDS	deaD	NC_008245.1	1522304	1524013	R	Similar to DEAD_KLEPN (P33906) Cold-shock DEAD-box protein A (ATP-dependent RNA helicase deaD) from Klebsiella pneumoniae (642 aa). FASTA: opt: 1669 Z-score: 1759.9 E(): 3.5e-90 Smith-Waterman score: 1669; 45.070 identity in 568 aa overlap; cold-shock DEAD-box protein A	complement(1522304..1524013)	Francisella tularensis subsp. tularensis FSC198	4199531
YP_667540.1	CDS	ppiC	NC_008245.1	1524078	1524356	R	Identical to Q9ETL6 Putative parvulin (Putative peptidyl-prolyl cis-trans isomerase) from Francisella tularensis ssp. tularensis strain SchuS4 (FSC237) (92 aa).; peptidyl-prolyl cis-trans isomerase	complement(1524078..1524356)	Francisella tularensis subsp. tularensis FSC198	4199934
YP_667541.1	CDS	galP2	NC_008245.1	1524451	1525845	R	Similar to GALP__ECOLI Galactose-proton symporter from E. coli (464 aa). FASTA: opt: 965 Z-score: 1103.1 E(): 1.4e-53 Smith-Waterman score: 965; 36.226 identity in 461 aa overlap; major facilitator superfamily galactose-proton symporter	complement(1524451..1525845)	Francisella tularensis subsp. tularensis FSC198	4199269
YP_667542.1	CDS	galP1	NC_008245.1	1525877	1527259	R	Similar to AAO70555 (Q8XEV6) Galactose-proton symport from Salmonella typhimurium (464 aa). FASTA: opt: 1295 Z-score: 1483.7 E(): 8.6e-75 Smith-Waterman score: 1295; 45.140 identity in 463 aa overlap; major facilitator superfamily galactose-proton symporter	complement(1525877..1527259)	Francisella tularensis subsp. tularensis FSC198	4199268
YP_667543.1	CDS	galT	NC_008245.1	1527350	1528375	D	catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase	1527350..1528375	Francisella tularensis subsp. tularensis FSC198	4199270
YP_667544.1	CDS	galK	NC_008245.1	1528378	1529526	D	Similar to GAL1_ACTPL Galactokinase from Actinobacillus pleuropneumoniae (384 aa) FASTA: opt: 959 Z-score: 1098.0 E(): 2.6e-53 Smith-Waterman score: 959; 38.710identity in 372 aa overlap; galactokinase	1528378..1529526	Francisella tularensis subsp. tularensis FSC198	4199266
YP_667545.1	CDS	FTF1477c	NC_008245.1	1529523	1529918	R	Similar to Q88NK0 Conserved hypothetical protein from Pseudomonas putida (139 aa). FASTA: opt: 362 Z-score: 463.4 E(): 5.9e-18 Smith-Waterman score: 362; 40.458 identity in 131 aa overlap ORF ftt1477c; hypothetical protein	complement(1529523..1529918)	Francisella tularensis subsp. tularensis FSC198	4200070
YP_667546.1	CDS	kdsB	NC_008245.1	1529911	1530663	R	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase	complement(1529911..1530663)	Francisella tularensis subsp. tularensis FSC198	4199507
YP_667547.1	CDS	FTF1479c	NC_008245.1	1530656	1530844	R	Similarity to Q8DAV0 Conserved hypothetical protein from Vibrio vulnificus (59 aa). FASTA: opt: 252 Z-score: 369.5 E(): 1e-12 Smith-Waterman score: 252; 56.140 identity in 57 aa overlap ORF ftt1479c; hypothetical protein	complement(1530656..1530844)	Francisella tularensis subsp. tularensis FSC198	4200071
YP_667548.1	CDS	FTF1480c	NC_008245.1	1531229	1531408	R	ORF ftt1480c; hypothetical protein	complement(1531229..1531408)	Francisella tularensis subsp. tularensis FSC198	4200072
YP_667549.1	CDS	isftu1	NC_008245.1	1531569	1532353	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(1531569..1532027,1532027..1532353))	Francisella tularensis subsp. tularensis FSC198	4200175
YP_667550.1	CDS	lpd	NC_008245.1	1532726	1534138	R	Similar to AAO90013 (Q83E67) Dihydrolipoamide dehydrogenase from Coxiella burnetti (474 aa). FASTA: opt: 2052 Z-score: 2129.3 E(): 9.5e-111 Smith-Waterman score: 2052; 65.890 identity in 472 aa overlap.; dihydrolipoamide dehydrogenase	complement(1532726..1534138)	Francisella tularensis subsp. tularensis FSC198	4199565
YP_667551.1	CDS	aceF	NC_008245.1	1534152	1536047	R	E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase	complement(1534152..1536047)	Francisella tularensis subsp. tularensis FSC198	4199751
YP_667552.1	CDS	aceE	NC_008245.1	1536065	1538746	R	E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1	complement(1536065..1538746)	Francisella tularensis subsp. tularensis FSC198	4199750
YP_667553.1	CDS	FTF1486c	NC_008245.1	1539046	1540182	R	Similar to AAO91321 (Q83AQ3) Hypothetical protein from Coxiella burnetti (388 aa). FASTA: opt: 858 Z-score: 1007.0 E(): 3.1e-48 Smith-Waterman score: 858 38.504 identity in 361 aa overlap ORF ftt1486c; hypothetical protein	complement(1539046..1540182)	Francisella tularensis subsp. tularensis FSC198	4200074
YP_667554.1	CDS	coaE	NC_008245.1	1540310	1540924	D	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase	1540310..1540924	Francisella tularensis subsp. tularensis FSC198	4200271
YP_667555.1	CDS	trpS	NC_008245.1	1541221	1542225	D	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase	1541221..1542225	Francisella tularensis subsp. tularensis FSC198	4200723
YP_667556.1	CDS	FTF1489	NC_008245.1	1542227	1542952	D	ORF ftt1489; hypothetical protein	1542227..1542952	Francisella tularensis subsp. tularensis FSC198	4200075
YP_667557.1	CDS	FTF1490	NC_008245.1	1542962	1544260	D	Similar to Q9RZK7 NA+/H+ antiporter, putative, from Deinococcus radiodurans (422 aa). FASTA: opt: 529 Z-score: 612.1 E(): 3.1e-26 Smith-Waterman score: 771; 36.211 identity in 417 aa overlap ORF ftt1490; Na+/H+ antiporter	1542962..1544260	Francisella tularensis subsp. tularensis FSC198	4200076
YP_667558.1	CDS	FTF1491c	NC_008245.1	1544659	1544973	R	ORF ftt1491c; hypothetical protein	complement(1544659..1544973)	Francisella tularensis subsp. tularensis FSC198	4200077
YP_667559.1	CDS	FTF1492c	NC_008245.1	1545069	1545695	R	ORF ftt1492c; hypothetical protein	complement(1545069..1545695)	Francisella tularensis subsp. tularensis FSC198	4200078
YP_667560.1	CDS	FTF1493c	NC_008245.1	1546185	1546580	R	ORF ftt1493c; hypothetical protein	complement(1546185..1546580)	Francisella tularensis subsp. tularensis FSC198	4200079
YP_667561.1	CDS	murQ	NC_008245.1	1546582	1547466	R	catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase	complement(1546582..1547466)	Francisella tularensis subsp. tularensis FSC198	4199875
YP_667562.1	CDS	FTF1495c	NC_008245.1	1547463	1549427	R	ORF ftt1495c; hypothetical protein	complement(1547463..1549427)	Francisella tularensis subsp. tularensis FSC198	4199876
YP_667563.1	CDS	FTF1496c	NC_008245.1	1549436	1550449	R	ORF ftt1496c; hypothetical protein	complement(1549436..1550449)	Francisella tularensis subsp. tularensis FSC198	4199877
YP_667564.1	CDS	FTF1497c	NC_008245.1	1550430	1550933	R	ORF ftt1497c; hypothetical protein	complement(1550430..1550933)	Francisella tularensis subsp. tularensis FSC198	4199878
YP_667565.1	CDS	accA	NC_008245.1	1550953	1551900	R	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha	complement(1550953..1551900)	Francisella tularensis subsp. tularensis FSC198	4199746
YP_667566.1	CDS	muts	NC_008245.1	1552034	1554607	D	This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS	1552034..1554607	Francisella tularensis subsp. tularensis FSC198	4200114
YP_667567.1	CDS	secB2	NC_008245.1	1554679	1555122	D	molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB	1554679..1555122	Francisella tularensis subsp. tularensis FSC198	4200735
YP_667568.1	CDS	FTF1502	NC_008245.1	1556563	1557780	D	Similar to AAP17334 (TRYP_ECOLI) Tyrosine-specific transport protein from E. coli (403 aa). FASTA: opt: 741 Z-score: 839.5 E(): 6.5e-39 Smith-Waterman score: 741; 32.663identity in 398 aa overlap ORF ftt1502; aromatic amino acid HAAP transporter	1556563..1557780	Francisella tularensis subsp. tularensis FSC198	4199880
YP_667569.1	CDS	xerC	NC_008245.1	1557790	1558668	D	Similar to Q88B11 Integrase/recombinase XerC from Pseudomonas syringae (295 aa). FASTA: opt: 790 Z-score: 939.6 E(): 1.7e-44 Smith-Waterman score: 790; 42.177 identity in 294 aa overlap.; integrase/recombinase XerC	1557790..1558668	Francisella tularensis subsp. tularensis FSC198	4200693
YP_667570.1	CDS	FTF1504	NC_008245.1	1558668	1559393	D	Similar to YHIQ_NEIGO P72077 Hypothetical 27.3kDa protein from Neisseria gonorrhoeae (254 aa). FASTA: opt: 350 Z-score: 423.8 E(): 9.3e-16 Smith-Waterman score: 350; 36.073 identity in 219 aa overlap. ORF ftt1504; hypothetical protein	1558668..1559393	Francisella tularensis subsp. tularensis FSC198	4199881
YP_667571.1	CDS	FTF1505c	NC_008245.1	1559400	1560014	R	ORF ftt1505c; hypothetical protein	complement(1559400..1560014)	Francisella tularensis subsp. tularensis FSC198	4199882
YP_667572.1	CDS	FTF1506	NC_008245.1	1560102	1560680	D	ORF ftt1506; hypothetical protein	1560102..1560680	Francisella tularensis subsp. tularensis FSC198	4199883
YP_667573.1	CDS	FTF1507	NC_008245.1	1560757	1561389	D	ORF ftt1507; hypothetical protein	1560757..1561389	Francisella tularensis subsp. tularensis FSC198	4199884
YP_667574.1	CDS	relA	NC_008245.1	1561505	1563448	R	Similar to Q8EBQ4 GTP pyrophosphokinase from Shewenella oneidensis (735 aa). FASTA: opt: 1566 Z-score: 1723.7 E(): 3.7e-88 Smith-Waterman score: 1639; 39.744 identity in 624 aa overlap; GTP pyrophosphokinase	complement(1561505..1563448)	Francisella tularensis subsp. tularensis FSC198	4200609
YP_667575.1	CDS	FTF1509c	NC_008245.1	1563817	1564173	R	ORF ftt1509c; hypothetical protein	complement(1563817..1564173)	Francisella tularensis subsp. tularensis FSC198	4199885
YP_667576.1	CDS	FTF1510c	NC_008245.1	1564207	1565403	R	Similar to Q8DAB5 Tyrosine-specific transport protein from Vibrio vulnificus (401 aa). FASTA: opt: 804 Z-score: 930.6 E(): 5.5e-44 Smith-Waterman score: 804; 35.309 identity in 405 aa overlap ORF ftt1510; aromatic amino acid HAAP transporter	complement(1564207..1565403)	Francisella tularensis subsp. tularensis FSC198	4199886
YP_667577.1	CDS	FTF1511	NC_008245.1	1565594	1566478	D	Similar to AAO90839 Membrane protein, putative from Coxiella burnetii (305 aa). FASTA: opt: 693 Z-score: 824.9 E(): 4.3e-38 Smith-Waterman score: 693; 38.776 identity in 294 aa overlap. ORF ftt1511; hypothetical protein	1565594..1566478	Francisella tularensis subsp. tularensis FSC198	4199887
YP_667578.1	CDS	dnaJ2	NC_008245.1	1566468	1567394	R	Similar to CAD85066 (Q82VD9) DnaJ N-terminal domain:DnaJ C terminal domain from Nitrosomonas europaea (314 aa). FASTA opt: 800 Z-score: 823.9 E(): 4.8e-38 39.482 identity in 309 aa overlap.; heat shock protein, hsp40	complement(1566468..1567394)	Francisella tularensis subsp. tularensis FSC198	4199355
YP_667579.1	CDS	FTF1514c	NC_008245.1	1568324	1568695	R	ORF ftt1514c; hypothetical protein	complement(1568324..1568695)	Francisella tularensis subsp. tularensis FSC198	4199889
YP_667580.1	CDS	FTF1515c	NC_008245.1	1568703	1569302	R	Similar to Q8XMV7 Hypothetical protein CPE0581 from Clostridium perfrigens (195 aa). FASTA: opt: 348 Z-score: 432.5 E(): 3.1e-16 Smith-Waterman score: 348; 33.333 identity in 189 aa overlap. FTF1563 is more likely to be phosphatidylcoline synthase. ORF ftt1515c; hypothetical protein	complement(1568703..1569302)	Francisella tularensis subsp. tularensis FSC198	4199890
YP_667581.1	CDS	FTF1517c	NC_008245.1	1570720	1571439	R	Similar to Q92KR0 hypothetical transmembrane protein from Rhizobium meliloti (266aa). FASTA: opt: 566 Z-score: 664.8 E(): 3.5e-29 Smith-Waterman score: 566; 40.090 identity in 222 aa overlap. ORF ftt1517c; hypothetical protein	complement(1570720..1571439)	Francisella tularensis subsp. tularensis FSC198	4199891
YP_667582.1	CDS	ogt	NC_008245.1	1571469	1572041	D	Similar to Q8A7W3 methylated-DNA--protein-cysteine methyltransferase from Bacteroides thetaiotaomicron (181aa). FASTA: opt: 443 Z-score: 536.8 bits: 106.7 E(): 4.8e-22 Smith-Waterman score: 443; 44.375 identity in 160 aa overlap. ogt in E.coli is a bifunctional protein containing an autotranscriptional activator at its carboxy domain and a methylated-DNA--protein-cysteine methyltransferase (MGMT) domain at its carboxy terminus. In Bacillus subtilis these two functions are independent and are referred to as adaA and adaB respectively; methylated-DNA--protein-cysteine methyltransferase	1571469..1572041	Francisella tularensis subsp. tularensis FSC198	4200760
YP_667583.1	CDS	gabP	NC_008245.1	1572525	1573862	R	Similar to Q8A4M6 glutamate/gamma-aminobutyrate anti-porter from Bacteroides thetaiotaomicron. FASTA: opt: 911 Z-score: 1001.3 E(): 6.4e-48 Smith-Waterman score: 911; 31.696identity in 448 aa overlap.; glutamate/gamma-aminobutyrate anti-porter	complement(1572525..1573862)	Francisella tularensis subsp. tularensis FSC198	4199206
YP_667584.1	CDS	FTF1522c	NC_008245.1	1575113	1575703	R	Similar to Q8P4A2, hypothetical protein XCC3808 from Xanthamonas campestris (258aa). FASTA: opt:421 Z-score: 521.1 E(): 3.6e-21 Smith-Waterman score: 421; 34.536 identity in 194 aa overlap ORF ftt1522c; hypothetical protein	complement(1575113..1575703)	Francisella tularensis subsp. tularensis FSC198	4199893
YP_667585.1	CDS	isftu2	NC_008245.1	1576072	1576815	R	ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa).; transposase	complement(1576072..1576815)	Francisella tularensis subsp. tularensis FSC198	4199297
YP_667586.1	CDS	hrpA	NC_008245.1	1577297	1581565	R	Similar to Q8ZE61 ATP-dependent helicase from Yersinia pestis (1280 aa). FASTA: opt: 2018 Z-score: 2071.8 E(): 1.5e-107 Smith-Waterman score: 2974; 38.714 identity in 1400 aa overlap; ATp-dependent helicase	complement(1577297..1581565)	Francisella tularensis subsp. tularensis FSC198	4200201
YP_667587.1	CDS	FTF1525c	NC_008245.1	1581589	1582476	R	ORF ftt1525c; hypothetical protein	complement(1581589..1582476)	Francisella tularensis subsp. tularensis FSC198	4200118
YP_667588.1	CDS	idh	NC_008245.1	1582490	1584733	R	Similar to Q8EDW2 Isocitrate dehydrogenase,NADP-dependent from Shewanella oneidensis (741 aa). FASTA: opt: 3146 Z-score: 3332.9 E(): 8.6e-178 65.574identity in 732 aa overlap; isocitrate dehydrogenase	complement(1582490..1584733)	Francisella tularensis subsp. tularensis FSC198	4200652
YP_667589.1	CDS	arsC2	NC_008245.1	1584737	1585102	R	Similar to Q87MH6 Arsenate reductase from Vibrio parahaemolyticus (116 aa). FASTA: opt: 287 Z-score: 374.9 E(): 5e-13 Smith-Waterman score: 287; 38.739 identity in 111 aa overlap; arsenate reductase	complement(1584737..1585102)	Francisella tularensis subsp. tularensis FSC198	4199687
YP_667590.1	CDS	fadD2	NC_008245.1	1585318	1587006	D	Similar to Q8EE09 Long-chain-fatty-acid--CoA ligase from Shewanella oneidensis (557 aa). FASTA: opt: 1556 Z-score: 1747.3 E(): 1.8e-89 Smith-Waterman score: 1556; 42.908identity in 557 aa overlap; long chain fatty acid CoA ligase	1585318..1587006	Francisella tularensis subsp. tularensis FSC198	4199403
YP_667591.2	CDS	fadE	NC_008245.1	1587044	1589284	D	functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase	1587044..1589284	Francisella tularensis subsp. tularensis FSC198	4199404
YP_667592.1	CDS	fadB/acbP	NC_008245.1	1589357	1592053	D	N-terminal (85 aa) similar to CBP_YEAST (P31787) Acyl-CoA-binding protein (ACBP) from Saccharomyces cerevisiae (86 aa). FASTA opt: 206 Z-score: 281.8 E(): 7.6e-08 Smith-Waterman score: 206; 44.444identity in 72 aa overlap. C-terminus (110-898) similar to Q8P986 3-hydroxacyl-CoA dehydrogenase from Xanthomonas campestris (790 aa). FASTA: opt: 2495 Z-score: 2747.5 E(): 3.5e-145 Smith-Waterman score: 2495;48.228 identity in 790 aa overlap No match to first 110 aa with Q8P986 or any other 3-hydroxacyl-CoA dehydrogenase. Acyl-CoA-binding protein has only been described in eukaryotes unknown EC_number 5.2.2.3; bifunctional 3-hydroxacyl-CoA dehydrogenase/acyl-CoA-binding protein	1589357..1592053	Francisella tularensis subsp. tularensis FSC198	4199401
YP_667593.1	CDS	fadA	NC_008245.1	1592066	1593253	D	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase	1592066..1593253	Francisella tularensis subsp. tularensis FSC198	4199684
YP_667594.1	CDS	FTF1532	NC_008245.1	1593315	1593803	D	Similar to Q8ABB1 Conserved hypothetical protein from Bacteriodes thetaiotaomicron (163 aa). FASTA: opt: 237 Z-score: 310.7 E(): 1.9e-09 Smith-Waterman score: 237; 27.097 identity in 155 aa overlap ORF ftt1532; hypothetical protein	1593315..1593803	Francisella tularensis subsp. tularensis FSC198	4200119
YP_667595.1	CDS	FTF1534c	NC_008245.1	1595463	1596878	R	Similar to Q8P596 Pre-B cell enhancing factor related protein from Xanthomonas campestris (468 aa). FASTA: opt: 1453 Z-score: 1660.8 E(): 1.2e-84 Smith-Waterman score: 1453; 49.260 identity in 473 aa overlap ORF ftt1534c; putative nicotinate phosphoribosyltransferase	complement(1595463..1596878)	Francisella tularensis subsp. tularensis FSC198	4200121
YP_667596.1	CDS	FTF1536c	NC_008245.1	1598221	1599135	R	Similar to Q8RGP8 Hypothetical protein from Mycoplasma penetrans (310 aa). FASTA: opt: 805 Z-score: 956.1 E(): 2.1e-45 Smith-Waterman score: 805; 42.308 identity in 312 aa overlap ORF ftt1536c; hypothetical protein	complement(1598221..1599135)	Francisella tularensis subsp. tularensis FSC198	4200123
YP_667597.1	CDS	FTF1537c	NC_008245.1	1599275	1600669	R	Similar to Q8DAW7 Conserved hypothetical protein from Vibrio vulnificus (448 aa). FASTA: opt: 455 Z-score: 511.9 E(): 1.2e-20 Smith-Waterman score: 520; 26.539 identity in 471 aa overlap ORF ftt1537c; hypothetical protein	complement(1599275..1600669)	Francisella tularensis subsp. tularensis FSC198	4200124
YP_667598.1	CDS	FTF1538c	NC_008245.1	1600675	1601658	R	ORF ftt1538c; hypothetical protein	complement(1600675..1601658)	Francisella tularensis subsp. tularensis FSC198	4200125
YP_667599.1	CDS	FTF1539c	NC_008245.1	1601669	1603099	R	Similar to Q9PJ34 Putative periplasmic protein from Campylobacter jejuni (445 aa). FASTA: opt: 520 Z-score: 539.8 E(): 3.2e-22 Smith-Waterman score: 530; 27.673 identity in 477 aa overlap ORF ftt1539c; hypothetical protein	complement(1601669..1603099)	Francisella tularensis subsp. tularensis FSC198	4200126
YP_667600.1	CDS	FTF1540c	NC_008245.1	1603156	1603764	R	Similar to Q8EHZ4 Conserved hypothetical protein from Shewanella oneidensis (197 aa). FASTA: opt: 542 Z-score: 654.0 E(): 1.4e-28 Smith-Waterman score: 542; 41.584 identity in 202 aa overlap ORF ftt1540c; hypothetical protein	complement(1603156..1603764)	Francisella tularensis subsp. tularensis FSC198	4200127
YP_667601.1	CDS	FTF1541c	NC_008245.1	1603967	1604341	R	ORF ftt1541c; hypothetical protein	complement(1603967..1604341)	Francisella tularensis subsp. tularensis FSC198	4200128
YP_667602.1	CDS	omp26	NC_008245.1	1604459	1604995	R	Similar to Q57483 Outer membrane protein 26 precursor (197 aa). FASTA: opt: 139 Z-score: 159.9 E(): 0.47 Smith-Waterman score: 139; 25.641 identity in 195 aa overlap; hypothetical protein	complement(1604459..1604995)	Francisella tularensis subsp. tularensis FSC198	4200763
YP_667603.1	CDS	FTF1543	NC_008245.1	1605138	1605827	D	Similar to Q8UGQ7 Two component response regulator from Agrobacterium tumefaciens (252 aa). FASTA: opt: 684 Z-score: 819.7 E(): 8.4e-38 Smith-Waterman score: 684; 45.333 identity in 225 aa overlap ORF ftt1543; two component response regulator	1605138..1605827	Francisella tularensis subsp. tularensis FSC198	4200129
YP_667604.1	CDS	isftu1	NC_008245.1	1609635	1610419	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(1609635..1609961,1609961..1610419)	Francisella tularensis subsp. tularensis FSC198	4200176
YP_667605.1	CDS	FTF1549	NC_008245.1	1611130	1611585	D	ORF ftt1549; hypothetical protein	1611130..1611585	Francisella tularensis subsp. tularensis FSC198	4200044
YP_667606.1	CDS	FTF1550	NC_008245.1	1611679	1612221	D	Similar to Q8EBW9 Conserved hypothetical protein (183 aa). FASTA: opt: 505 Z-score: 618.4 E(): 1.4e-26 Smith-Waterman score: 505; 40.237identity in 169 aa overlap ORF ftt1550; hypothetical protein	1611679..1612221	Francisella tularensis subsp. tularensis FSC198	4200045
YP_667607.1	CDS	FTF1551	NC_008245.1	1612223	1612966	D	Similar to Q888B1 Oxidoreductase,short chain dehydrogenase from Pseudomonas syringae (262 aa). FASTA: opt: 390 Z-score: 468.5 E(): 3e-18 Smith-Waterman score: 445; 32.143 identity in 252 aa overlap ORF ftt1551; oxidoreductase	1612223..1612966	Francisella tularensis subsp. tularensis FSC198	4200046
YP_667608.1	CDS	ole1	NC_008245.1	1612980	1613807	D	Similar to Q8PMP8 Delta 9 acyl-lipid fatty acid desaturase from Xanthomonas axonopodis (298 aa). FASTA: opt: 851 Z-score: 1027.5 E(): 2.2e-49 Smith-Waterman score: 851; 45.149identity in 268 aa overlap; Delta 9 acyl-lipid fatty acid desaturase	1612980..1613807	Francisella tularensis subsp. tularensis FSC198	4200761
YP_667609.1	CDS	rnr	NC_008245.1	1613831	1616128	R	Similar to Q8EAG7 Ribonuclease R from (808 aa). FASTA: opt: 1840 Z-score: 1989.4 E(): 5.9e-103 Smith-Waterman score: 1863; 41.602 identity in 774 aa overlap; ribonuclease R	complement(1613831..1616128)	Francisella tularensis subsp. tularensis FSC198	4200769
YP_667610.1	CDS	truB	NC_008245.1	1616121	1617029	R	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B	complement(1616121..1617029)	Francisella tularensis subsp. tularensis FSC198	4200725
YP_667611.1	CDS	rnc	NC_008245.1	1617016	1617708	R	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III	complement(1617016..1617708)	Francisella tularensis subsp. tularensis FSC198	4199225
YP_667612.1	CDS	lepB	NC_008245.1	1617715	1618578	R	Similar to AAO90612 9 83CL5) Signal peptidase I from Coxiella burnetii (259 aa). FASTA: opt: 716 Z-score: 839.6 E(): 6.5e-39 Smith-Waterman score: 717; 39.416 identity in 274 aa overlap; signal peptidase I	complement(1617715..1618578)	Francisella tularensis subsp. tularensis FSC198	4199512
YP_667613.1	CDS	FTF1557c	NC_008245.1	1618583	1619269	R	Similar to AAO90736 DNA-binding response regulator from Coxiella burnetii (223 aa). FASTA: opt: 669 Z-score: 771.7 E(): 3.9e-35 Smith-Waterman score: 669; 45.778 identity in 225 aa overlap ORF ftt1557c; two-component response regulator	complement(1618583..1619269)	Francisella tularensis subsp. tularensis FSC198	4200047
YP_667614.1	CDS	proC	NC_008245.1	1621046	1621870	R	Similar to Q87LJ5 Pyrroline-5-carboxylate reductase from Vibrio parahaemolyticus (272 aa). FASTA: opt: 656 Z-score: 770.0 E(): 4.9e-35 Smith-Waterman score: 656; 39.925identity in 268 aa overlap; pyrroline-5-carboxylate reductase	complement(1621046..1621870)	Francisella tularensis subsp. tularensis FSC198	4199943
YP_667615.1	CDS	FTF1560	NC_008245.1	1621977	1622555	D	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase	1621977..1622555	Francisella tularensis subsp. tularensis FSC198	4200049
YP_667616.1	CDS	kdtA	NC_008245.1	1622660	1623955	D	Similar to Q87VF9 3-deoxy-D-manno-octulosonic-acid transferase from Pseudomonas syringae (447 aa). FASTA: opt: 1099 Z-score: 1251.3 E(): 7.6e-62 Smith-Waterman score: 1099; 40.143 identity in 421 aa overlap; 3-deoxy-D-manno-octulosonic-acid transferase	1622660..1623955	Francisella tularensis subsp. tularensis FSC198	4199509
YP_667617.1	CDS	ispA	NC_008245.1	1623952	1624833	D	Similar to P45204 Geranyltranstransferase from Haemophilus influenzae (295 aa). FASTA: opt: 728 Z-score: 859.4 E(): 5.1e-40 Smith-Waterman score: 728; 43.972 identity in 282 aa overlap; geranyltranstransferase	1623952..1624833	Francisella tularensis subsp. tularensis FSC198	4199298
YP_667618.1	CDS	pcs	NC_008245.1	1624881	1625645	D	Similar to O51265 Phosphatidyltransferase from Borrelia burgdorferi (234 aa). FASTA: opt: 438 Z-score: 531.7 E(): 9.1e-22 Smith-Waterman score: 496; 35.743 identity in 249 aa overlap; phosphatidylcholine synthase	1624881..1625645	Francisella tularensis subsp. tularensis FSC198	4199229
YP_667619.1	CDS	FTF1564	NC_008245.1	1625715	1626524	D	Similar to Q9I6Z1 Hypothetical protein PA0141 from Pseudomonas aeruginosa (298 aa). FASTA: opt: 1210 Z-score: 1427.9 E(): 1.1e-71 Smith-Waterman score: 1210; 62.738 identity in 263 aa overlap ORF ftt1564; hypothetical protein	1625715..1626524	Francisella tularensis subsp. tularensis FSC198	4200050
YP_667620.1	CDS	FTF1566c	NC_008245.1	1628345	1628641	R	ORF ftt1566c; hypothetical protein	complement(1628345..1628641)	Francisella tularensis subsp. tularensis FSC198	4200052
YP_667621.1	CDS	FTF1567c	NC_008245.1	1628812	1629399	R	ORF ftt1567c; hypothetical protein	complement(1628812..1629399)	Francisella tularensis subsp. tularensis FSC198	4200053
YP_667622.1	CDS	lpxB	NC_008245.1	1629458	1630600	R	catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase	complement(1629458..1630600)	Francisella tularensis subsp. tularensis FSC198	4199570
YP_667623.1	CDS	lpxA	NC_008245.1	1630600	1631379	R	catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase	complement(1630600..1631379)	Francisella tularensis subsp. tularensis FSC198	4199569
YP_667624.1	CDS	fabZ	NC_008245.1	1631382	1631873	R	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase	complement(1631382..1631873)	Francisella tularensis subsp. tularensis FSC198	4199683
YP_667625.1	CDS	lpxD	NC_008245.1	1631888	1632901	R	adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	complement(1631888..1632901)	Francisella tularensis subsp. tularensis FSC198	4199572
YP_667626.1	CDS	ompH	NC_008245.1	1632920	1633423	R	Similar to OMPH_YEREN Cationic 19 kDa outer membrane protein from Yersinia enterocolitica (169 aa). FASTA: opt: 245 Z-score: 251.8 E(): 3.6e-06 Smith-Waterman score: 245; 28.000 identity in 150 aa overlap; outer membrane protein OmpH	complement(1632920..1633423)	Francisella tularensis subsp. tularensis FSC198	4200080
YP_667627.1	CDS	FTF1573c	NC_008245.1	1633559	1635937	R	Similar to Q88MH2 Outer membrane protein,bacterial surface antigen family from Pseudomonas putida (786 aa). FASTA: opt: 1561 Z-score: 1675.2 E(): 1.9e-85 Smith-Waterman score: 1561; 32.959 identity in 801 aa overlap ORF ftt1573c; outer membrane protein	complement(1633559..1635937)	Francisella tularensis subsp. tularensis FSC198	4200054
YP_667628.1	CDS	dxr	NC_008245.1	1635943	1637100	R	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase	complement(1635943..1637100)	Francisella tularensis subsp. tularensis FSC198	4199667
YP_667629.1	CDS	gyrA	NC_008245.1	1637106	1639712	R	Similar to GYRA_SALTY (P37411) DNA gyrase subunit A from Salmonella typhimurium (878 aa). FASTA: opt: 3442 Z-score: 3640.6 E(): 6.3e-195 Smith-Waterman score: 3442; 60.665 identity in 872 aa overlap; DNA gyrase subunit A	complement(1637106..1639712)	Francisella tularensis subsp. tularensis FSC198	4200367
YP_667630.1	CDS	FTF1576	NC_008245.1	1639971	1640516	D	ORF ftt1576; hypothetical protein	1639971..1640516	Francisella tularensis subsp. tularensis FSC198	4200055
YP_667631.1	CDS	FTF1577	NC_008245.1	1640552	1641637	D	ORF ftt1577; hypothetical protein	1640552..1641637	Francisella tularensis subsp. tularensis FSC198	4200056
YP_667632.1	CDS	ung	NC_008245.1	1641672	1642334	R	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase	complement(1641672..1642334)	Francisella tularensis subsp. tularensis FSC198	4198983
YP_667633.1	CDS	FTF1579c	NC_008245.1	1642331	1645204	R	Similar to O25314 Type III restriction enzyme R protein from Helicobacter pylori (1001 aa). FASTA: opt: 1491 Z-score: 1485.7 E(): 6.6e-75 Smith-Waterman score: 2480; 42.828 identity in 990 aa overlap ORF ftt1579c; Type III restriction enzyme	complement(1642331..1645204)	Francisella tularensis subsp. tularensis FSC198	4200057
YP_667634.1	CDS	FTF1580c	NC_008245.1	1645441	1645971	R	Identical to AAP83333 Hypothetical protein from Francisella tularensis ssp. tularensis strain SchuS4 (FSC237) (176 aa). ORF ftt1580c; hypothetical protein	complement(1645441..1645971)	Francisella tularensis subsp. tularensis FSC198	4200058
YP_667635.1	CDS	FTF1581c	NC_008245.1	1646040	1646324	R	Similar to Q8DE33 Predicted endonuclease from Vibrio vulnificus (94 aa). FASTA: opt: 387 Z-score: 525.2 E(): 2.1e-21 Smith-Waterman score: 387; 61.798identity in 89 aa overlap ORF ftt1581c; endonuclease	complement(1646040..1646324)	Francisella tularensis subsp. tularensis FSC198	4200059
YP_667636.1	CDS	isftu1	NC_008245.1	1648680	1649464	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(1648680..1649138,1649138..1649464))	Francisella tularensis subsp. tularensis FSC198	4200177
YP_667637.1	CDS	FTF1585	NC_008245.1	1649546	1649710	D	ORF ftt1585; hypothetical protein	1649546..1649710	Francisella tularensis subsp. tularensis FSC198	4199705
YP_667638.1	CDS	FTF1586c	NC_008245.1	1649724	1650005	R	ORF ftt1586c; hypothetical protein	complement(1649724..1650005)	Francisella tularensis subsp. tularensis FSC198	4199706
YP_667639.1	CDS	FTF1589c	NC_008245.1	1651886	1652629	R	ORF ftt1589c; hypothetical protein	complement(1651886..1652629)	Francisella tularensis subsp. tularensis FSC198	4199709
YP_667640.1	CDS	ubiG	NC_008245.1	1652632	1653327	R	Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase	complement(1652632..1653327)	Francisella tularensis subsp. tularensis FSC198	4198979
YP_667641.1	CDS	FTF1591	NC_008245.1	1653430	1654569	D	Similar to Q9Z674 Lipoprotein from Zymomonas mobilis (256 aa). FASTA: opt: 352 Z-score: 404.8 E(): 1.1e-14 Smith-Waterman score: 352; 31.739 identity in 230 aa overlap ORF ftt1591; lipoprotein	1653430..1654569	Francisella tularensis subsp. tularensis FSC198	4199710
YP_667642.1	CDS	FTF1594	NC_008245.1	1658492	1659484	D	Similar to Q8D7C4 Transcriptional regulator from Vibrio vulnificus (301 aa). FASTA: opt: 364 Z-score: 428.7 E(): 5e-16 Smith-Waterman score: 364; 33.010 identity in 206 aa overlap ORF ftt1594; LysR family transcriptional regulator	1658492..1659484	Francisella tularensis subsp. tularensis FSC198	4199713
YP_667643.1	CDS	FTF1595	NC_008245.1	1659725	1659880	D	ORF ftt1595; hypothetical protein	1659725..1659880	Francisella tularensis subsp. tularensis FSC198	4199714
YP_667644.1	CDS	FTF1596	NC_008245.1	1660053	1660451	D	ORF ftt1596; hypothetical protein	1660053..1660451	Francisella tularensis subsp. tularensis FSC198	4199715
YP_667645.1	CDS	FTF1597	NC_008245.1	1660518	1661975	D	ORF ftt1597; hypothetical protein	1660518..1661975	Francisella tularensis subsp. tularensis FSC198	4199716
YP_667646.1	CDS	FTF1598	NC_008245.1	1662039	1664873	D	This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein. ORF ftt1598; hypothetical protein	1662039..1664873	Francisella tularensis subsp. tularensis FSC198	4199717
YP_667647.1	CDS	isftu1	NC_008245.1	1664970	1665754	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(1664970..1665428,1665428..1665754))	Francisella tularensis subsp. tularensis FSC198	4200178
YP_667648.1	CDS	fumA	NC_008245.1	1666239	1667753	R	Similar to Q87NJ5 Fumarate hydratase, class I from Vibrio parahaemolyticus (505 aa). FASTA: opt: 2398 Z-score: 2635.2 E(): 6.3e-139 Smith-Waterman score: 2398; 69.384 identity in 503 aa overlap; fumerate hydratase	complement(1666239..1667753)	Francisella tularensis subsp. tularensis FSC198	4199200
YP_667649.1	CDS	recG	NC_008245.1	1668508	1670547	R	Similar to Q88C73 ATP-dependent DNA helicase RecG from Pseudomonas putida (692 aa). FASTA: opt: 1698 Z-score: 1867.5 E(): 3.6e-96 Smith-Waterman score: 1698; 41.314 identity in 685 aa overlap; ATP-dependent DNA helicase RecG	complement(1668508..1670547)	Francisella tularensis subsp. tularensis FSC198	4200604
YP_667650.1	CDS	FTF1602	NC_008245.1	1670677	1671021	D	ORF ftt1602; hypothetical protein	1670677..1671021	Francisella tularensis subsp. tularensis FSC198	4199718
YP_667651.1	CDS	rpmB	NC_008245.1	1671155	1671391	D	required for 70S ribosome assembly; 50S ribosomal protein L28	1671155..1671391	Francisella tularensis subsp. tularensis FSC198	4199003
YP_667652.1	CDS	rpmG	NC_008245.1	1671418	1671573	D	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33	1671418..1671573	Francisella tularensis subsp. tularensis FSC198	4199007
YP_667653.1	CDS	minC	NC_008245.1	1671608	1672294	D	Similar to Q87RC3 Septum site-determining protein MinC from Vibrio parahaemolyticus (220 aa). FASTA: opt: 444 Z-score: 518.9 E(): 4.7e-21 Smith-Waterman score: 444; 39.196 identity in 199 aa overlap; septum site-determining protein MinC	1671608..1672294	Francisella tularensis subsp. tularensis FSC198	4199846
YP_667654.1	CDS	minD	NC_008245.1	1672334	1673158	D	Similar to Q8FWX1 Septum site-determining protein MinD from Brucella suis(271 aa). FASTA: opt: 1091 Z-score: 1181.8 E(): 5.6e-58 Smith-Waterman score: 1091; 62.825 identity in 269 aa overlap; septum site-determining protein MinD	1672334..1673158	Francisella tularensis subsp. tularensis FSC198	4199847
YP_667655.1	CDS	minE	NC_008245.1	1673161	1673433	D	works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE	1673161..1673433	Francisella tularensis subsp. tularensis FSC198	4199848
YP_667656.1	CDS	FTF1608	NC_008245.1	1673447	1674250	D	Similar to YRBF_HAEIN Probable ABC transporter ATP-binding protein HI1087 from Haemophilus influenzae (264 aa). FASTA: opt: 861 Z-score: 970.8 E(): 3.2e-46 Smith-Waterman score: 861; 50.958identity in 261 aa overlap Equivalent to yrbF of yrb operon in E.coli ORF ftt1608; ABC transporter ATP-binding protein	1673447..1674250	Francisella tularensis subsp. tularensis FSC198	4199719
YP_667657.1	CDS	FTF1609	NC_008245.1	1674254	1675018	D	Similar Q8VUQ9 Toluene resistance protein Trg1 from Pseudomonas putida (265 aa). FASTA: opt: 793 Z-score: 934.5 E(): 3.4e-44 Smith-Waterman score: 793; 55.869 identity in 213 aa overlap Equivalent to yrbE of yrb operon in E.coli ORF ftt1609; ABC transporter membrane protein	1674254..1675018	Francisella tularensis subsp. tularensis FSC198	4199720
YP_667658.1	CDS	FTF1610	NC_008245.1	1675018	1675551	D	Similar to YRBD_HAEIN P45029 Hypothetical protein HI1085 from Haemophilus influenzae (167 aa). FASTA: opt: 256 Z-score: 320.6 E(): 5.3e-10 Smith-Waterman score: 281; 37.640identity in 178 aa overlap. Equivalent to yrbD of yrb operon in E.coli ORF ftt1610; hypothetical protein	1675018..1675551	Francisella tularensis subsp. tularensis FSC198	4199721
YP_667659.1	CDS	FTF1611	NC_008245.1	1675619	1676287	D	Similar to YRBC_ECOLI Protein yrbC precursor from E. coli (211 aa). FASTA: opt: 230 Z-score: 278.3 E(): 1.2e-07 Smith-Waterman score: 230; 26.147 identity in 218 aa overlap Equivalent to yrbC of yrb operon in E.coli ORF ftt1611; hypothetical protein	1675619..1676287	Francisella tularensis subsp. tularensis FSC198	4199722
YP_667660.1	CDS	FTF1612	NC_008245.1	1676287	1676580	D	Similar to YRBB_ECOLI Hypothetical protein yrbB from E. coli (97 aa). FASTA: opt: 116 Z-score: 165.8 E(): 0.22 Smith-Waterman score: 116; 31.915identity in 47 aa overlap Equivalent to yrbB of yrb operon in E.coli ORF ftt1612; hypothetical protein	1676287..1676580	Francisella tularensis subsp. tularensis FSC198	4199723
YP_667661.1	CDS	FTF1613	NC_008245.1	1676597	1676833	D	Similar to Q8ZB55 BolA-like protein from Yersinia pestis (87 aa). FASTA: opt: 163 Z-score: 236.9 E(): 2.4e-05 Smith-Waterman score: 163; 35.526 identity in 76 aa overlap Equivalent to yrbA of yrb operon in E.coli ORF ftt1613; BolA-like protein	1676597..1676833	Francisella tularensis subsp. tularensis FSC198	4199247
YP_667662.1	CDS	FTF1614c	NC_008245.1	1677113	1677796	R	ORF ftt1614c; hypothetical protein	complement(1677113..1677796)	Francisella tularensis subsp. tularensis FSC198	4199248
YP_667663.1	CDS	isftu1	NC_008245.1	1678030	1678814	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(1678030..1678356,1678356..1678814)	Francisella tularensis subsp. tularensis FSC198	4200179
YP_667664.1	CDS	cysS	NC_008245.1	1679286	1680680	D	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase	1679286..1680680	Francisella tularensis subsp. tularensis FSC198	4199523
YP_667665.1	CDS	hemK	NC_008245.1	1680684	1681628	D	involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase	1680684..1681628	Francisella tularensis subsp. tularensis FSC198	4200377
YP_667666.1	CDS	isftu1	NC_008245.1	1683279	1684063	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(1683279..1683605,1683605..1684063)	Francisella tularensis subsp. tularensis FSC198	4200180
YP_667667.1	CDS	FTF1621c	NC_008245.1	1684472	1685323	R	ORF ftt1621c; hypothetical protein	complement(1684472..1685323)	Francisella tularensis subsp. tularensis FSC198	4199251
YP_667668.1	CDS	FTF1622c	NC_008245.1	1685336	1686256	R	ORF ftt1622c; hypothetical protein	complement(1685336..1686256)	Francisella tularensis subsp. tularensis FSC198	4199252
YP_667669.1	CDS	FTF1623c	NC_008245.1	1686275	1686595	R	ORF ftt1623c; hypothetical protein	complement(1686275..1686595)	Francisella tularensis subsp. tularensis FSC198	4199253
YP_667670.1	CDS	FTF1624c	NC_008245.1	1686667	1686987	R	ORF ftt1624c; hypothetical protein	complement(1686667..1686987)	Francisella tularensis subsp. tularensis FSC198	4199254
YP_667671.1	CDS	FTF1625c	NC_008245.1	1687087	1687677	R	ORF ftt1625c; hypothetical protein	complement(1687087..1687677)	Francisella tularensis subsp. tularensis FSC198	4199255
YP_667672.1	CDS	FTF1626c	NC_008245.1	1687688	1689094	R	ORF ftt1626c; hypothetical protein	complement(1687688..1689094)	Francisella tularensis subsp. tularensis FSC198	4199256
YP_667673.1	CDS	FTF1627c	NC_008245.1	1689091	1689894	R	ORF ftt1627c; hypothetical protein	complement(1689091..1689894)	Francisella tularensis subsp. tularensis FSC198	4199257
YP_667674.1	CDS	FTF1628c	NC_008245.1	1690295	1691605	R	Similar to Q88C61 putative metal ion transporter from Pseudomonas putida (446 aa). FASTA: opt: 1033 Z-score: 1180.6 E(): 6.5e-58 Smith-Waterman score: 1035; 40.455 identity in 440 aa overlap ORF ftt1628c; metal ion transporter	complement(1690295..1691605)	Francisella tularensis subsp. tularensis FSC198	4199258
YP_667675.1	CDS	FTF1629c	NC_008245.1	1691616	1693295	R	ORF ftt1629c; hypothetical protein	complement(1691616..1693295)	Francisella tularensis subsp. tularensis FSC198	4199259
YP_667676.1	CDS	putP	NC_008245.1	1693366	1694832	R	Similar to PUTP_ECOLI Sodium/proline symporter from E. coli (501 aa). FASTA: opt: 1536 Z-score: 1735.2 E(): 8.4e-89 Smith-Waterman score: 1536; 46.531identity in 490 aa overlap; Sodium/proline permease	complement(1693366..1694832)	Francisella tularensis subsp. tularensis FSC198	4199127
YP_667677.1	CDS	glpX	NC_008245.1	1695138	1696124	R	type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II	complement(1695138..1696124)	Francisella tularensis subsp. tularensis FSC198	4200294
YP_667678.1	CDS	FTF1632c	NC_008245.1	1696144	1696782	R	Similar to AAO91263 (Q83AV9) Hypothetical protein from Coxiella burnetti (205 aa). FASTA: opt: 552 Z-score: 685.2 E(): 2.6e-30 Smith-Waterman score: 552; 41.000 identity in 200 aa overlap ORF ftt1632c; hypothetical protein	complement(1696144..1696782)	Francisella tularensis subsp. tularensis FSC198	4199260
YP_667679.1	CDS	FTF1633c	NC_008245.1	1696791	1698245	R	Similiar to AAP09999 (Q81BU4) Lysine-specific permease from Bacillus cereus (491 aa). FASTA: opt: 1734 Z-score: 1972.4 bits: 374.4 E(): 5.2e-102 Smith-Waterman score: 1817; 53.459 identity in 477 aa overlap ORF ftt1633c; amino acid transporter	complement(1696791..1698245)	Francisella tularensis subsp. tularensis FSC198	4199261
YP_667680.1	CDS	FTF1634c	NC_008245.1	1698493	1699161	R	ORF ftt1634c; hypothetical protein	complement(1698493..1699161)	Francisella tularensis subsp. tularensis FSC198	4199262
YP_667681.1	CDS	ftsK	NC_008245.1	1699283	1701784	D	Similar to Q9I0M3 Cell division protein FtsK from Rickettsia prowazekii (811 aa). FASTA: opt: 2030 Z-score: 2059.0 E(): 7.7e-107 Smith-Waterman score: 2197; 45.808 identity in 823 aa overlap; cell division protein	1699283..1701784	Francisella tularensis subsp. tularensis FSC198	4199195
YP_667682.1	CDS	lolA	NC_008245.1	1701785	1702402	D	Similar to LOLA_PSEAE (Q9I0M4) Outer-membrane lipoproteins carrier from Pseudomonas aeruginosa (208 aa). FASTA: opt: 384 Z-score: 440.9 E(): 1e-16 Smith-Waterman score: 384; 30.476 identity in 210 aa overlap; lipoprotein releasing system subunit A, outer membrane lipoproteins carrier	1701785..1702402	Francisella tularensis subsp. tularensis FSC198	4199558
YP_667683.1	CDS	FTF1637c	NC_008245.1	1702800	1703003	R	ORF ftt1637c; hypothetical protein	complement(1702800..1703003)	Francisella tularensis subsp. tularensis FSC198	4199263
YP_667684.1	CDS	trkH	NC_008245.1	1703115	1704569	D	Similar to Q9KNI3 Potassium uptake protein TrkH from Vibrio cholerae (485 aa). FASTA: opt: 1470 Z-score: 1682.5 E(): 7.3e-86 Smith-Waterman score: 1470; 43.827 identity in 486 aa overlap; potassium uptake protein	1703115..1704569	Francisella tularensis subsp. tularensis FSC198	4199862
YP_667685.1	CDS	FTF1639c	NC_008245.1	1704584	1705129	R	ORF ftt1639c; hypothetical protein	complement(1704584..1705129)	Francisella tularensis subsp. tularensis FSC198	4199264
YP_667686.1	CDS	FTF1644	NC_008245.1	1708673	1710097	D	Similar to O86076 Sucrose hydrolase from E. coli (477 aa). FASTA: opt: 787 Z-score: 912.8 E(): 5.4e-43 Smith-Waterman score: 787; 31.929 identity in 451 aa overlap ORF ftt1644; Beta-fructofuranosidase	1708673..1710097	Francisella tularensis subsp. tularensis FSC198	4199820
YP_667687.1	CDS	FTF1645	NC_008245.1	1710116	1711348	D	Similar to Q8EDM5 Conserved hypothetical protein from Shewanella oneidensis (384 aa). FASTA: opt: 372 Z-score: 419.7 E(): 1.6e-15 Smith-Waterman score: 372; 23.018 identity in 391 aa overlap ORF ftt1645; hypothetical protein	1710116..1711348	Francisella tularensis subsp. tularensis FSC198	4199821
YP_667688.1	CDS	dtd	NC_008245.1	1711590	1711919	D	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase	1711590..1711919	Francisella tularensis subsp. tularensis FSC198	4199361
YP_667689.1	CDS	pyrD	NC_008245.1	1712290	1713036	R	Similar to Q9WYG8 Dihydroorotate dehydrogenase from Pyrobaculum aerophilum (297 aa). FASTA: opt: 148 Z-score: 178.6 E(): 0.043 Smith-Waterman score: 191; 26.568 identity in 271 aa overlap; diyroorotate dehydrogenase	complement(1712290..1713036)	Francisella tularensis subsp. tularensis FSC198	4199131
YP_667690.1	CDS	pyrF	NC_008245.1	1713038	1713682	R	Similar to PYRF_STAAM (Q9LCT0) Orotidine 5'-phosphate decarboxylase from Bradyrhizobium japonicum (237 aa). FASTA: opt: 228 z-score: 280.6 E(): 8.8e-08 Smith-Waterman score: 243; 28.061identity in 196 aa overlap; orotidine 5'-phosphate decarboxylase	complement(1713038..1713682)	Francisella tularensis subsp. tularensis FSC198	4199133
YP_667691.1	CDS	FTF1650c	NC_008245.1	1717374	1717922	R	Similar to Q93LJ4 Periplasmic monofunctional chorismate mutase from Salmonella typhimurium (181 aa). FASTA: opt: 186 Z-score: 223.0 E(): 0.00014 Smith-Waterman score: 186; 31.746 identity in 126 aa overlap ORF ftt1650; chorismate mutase	complement(1717374..1717922)	Francisella tularensis subsp. tularensis FSC198	4199823
YP_667692.1	CDS	FTF1651	NC_008245.1	1718074	1718700	D	Similar to Q8KDD5 Hypothetical protein from Chlorobium tepidum (215 aa). FASTA: opt: 569 z-score: 706.8 E(): 1.6e-31 Smith-Waterman score: 569; 40.580 identity in 207 aa overlap ORF ftt1651; hypothetical protein	1718074..1718700	Francisella tularensis subsp. tularensis FSC198	4199824
YP_667693.1	CDS	FTF1652c	NC_008245.1	1718701	1719570	R	Similar to Q8EFC8 Transcriptional regulator, LysR family from Shewanella oneidensis (291 aa). FASTA: opt: 443 Z-score: 527.9 E(): 1.5e-21 Smith-Waterman score: 443; 29.831 identity in 295 aa overlap ORF ftt1652c; LysR family transcriptional regulator	complement(1718701..1719570)	Francisella tularensis subsp. tularensis FSC198	4199825
YP_667694.1	CDS	FTF1653	NC_008245.1	1719696	1720103	D	ORF ftt1653; hypothetical protein	1719696..1720103	Francisella tularensis subsp. tularensis FSC198	4199826
YP_667695.1	CDS	emrA2	NC_008245.1	1720192	1721157	D	Similar to AAO90332 (Q83DE0) Multidrug resistance protein from Coxiella burnetii (331 aa). FASTA: opt: 406 z-score: 447.9 E(): 4.2e-17 Smith-Waterman score: 406; 28.135 identity in 327 aa overlap; HlyD family secretion protein	1720192..1721157	Francisella tularensis subsp. tularensis FSC198	4199673
YP_667696.1	CDS	FTF1655	NC_008245.1	1721132	1722196	D	ORF ftt1655; hypothetical protein	1721132..1722196	Francisella tularensis subsp. tularensis FSC198	4199827
YP_667697.1	CDS	FTF1656c	NC_008245.1	1722312	1722863	R	Similiar to Q8PGE2 Hypothetical protein from Xanthomonas axonopodis(186 aa). FASTA: opt: 578 Z-score: 703.0 E(): 2.6e-31 Smith-Waterman score: 578; 51.462 identity in 171 aa overlap ORF ftt1656c; hypothetical protein	complement(1722312..1722863)	Francisella tularensis subsp. tularensis FSC198	4199828
YP_667698.1	CDS	FTF1657c	NC_008245.1	1723327	1723530	R	ORF ftt1657c; hypothetical protein	complement(1723327..1723530)	Francisella tularensis subsp. tularensis FSC198	4199829
YP_667699.1	CDS	FTF1658c	NC_008245.1	1723577	1723831	R	Similar to BAC68773 (Q82P70) Hypothetical protein from Streptomyces avermitilis (95 aa). FASTA: opt: 135 Z-score: 188.6 E(): 0.012 Smith-Waterman score: 135; 25.316 identity in 79 aa overlap ORF ftt1658c; hypothetical protein	complement(1723577..1723831)	Francisella tularensis subsp. tularensis FSC198	4199830
YP_667700.1	CDS	FTF1659	NC_008245.1	1724084	1725109	D	ORF ftt1659; hypothetical protein	1724084..1725109	Francisella tularensis subsp. tularensis FSC198	4199831
YP_667701.1	CDS	pyrC	NC_008245.1	1725137	1726483	R	Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase	complement(1725137..1726483)	Francisella tularensis subsp. tularensis FSC198	4199130
YP_667702.1	CDS	tmpT	NC_008245.1	1726615	1727295	D	catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide; thiopurine S-methyltransferase	1726615..1727295	Francisella tularensis subsp. tularensis FSC198	4199147
YP_667703.1	CDS	carA	NC_008245.1	1728889	1730055	D	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit	1728889..1730055	Francisella tularensis subsp. tularensis FSC198	4200315
YP_667704.1	CDS	carB	NC_008245.1	1730060	1733344	D	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit	1730060..1733344	Francisella tularensis subsp. tularensis FSC198	4200316
YP_667705.1	CDS	pyrB	NC_008245.1	1733486	1734406	D	Similar to PYRB_METJA Aspartate carbamoyltransferase from Methanococcus jannaschii (306 aa). FASTA: opt: 943 Z-score: 1081.5 E(): 2.2e-52 Smith-Waterman score: 943; 49.338 identity in 302 aa overlap; aspartate carbamoyltransferase	1733486..1734406	Francisella tularensis subsp. tularensis FSC198	4199129
YP_667706.1	CDS	FTF1666c	NC_008245.1	1734419	1735306	R	Similar to AAP10961 (Q819E3) 3-hydroxyisobutyrate dehydrogenase from Bacillus cereus (292 aa). FASTA: opt: 384 z-score: 452.2 E(): 2.4e-17 Smith-Waterman score: 384; 24.483 identity in 290 aa overlap ORF ftt1666c; 3-hydroxyisobutyrate dehydrogenase	complement(1734419..1735306)	Francisella tularensis subsp. tularensis FSC198	4199833
YP_667707.1	CDS	FTF1667	NC_008245.1	1735794	1736030	D	ORF ftt1667; hypothetical protein	1735794..1736030	Francisella tularensis subsp. tularensis FSC198	4199834
YP_667708.1	CDS	sdaC2	NC_008245.1	1736357	1737580	D	Similar to Q8ZGH6 Serine transporter from Yersinia pestis (433 aa). FASTA: opt: 1336 Z-score: 1510.1 E(): 2.9e-76 Smith-Waterman score: 1336; 46.078identity in 408 aa overlap.; serine transporter	1736357..1737580	Francisella tularensis subsp. tularensis FSC198	4200728
YP_667709.1	CDS	isftu1	NC_008245.1	1738564	1739348	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(1738564..1738890,1738890..1739348)	Francisella tularensis subsp. tularensis FSC198	4200182
YP_667710.1	CDS	ribD	NC_008245.1	1740427	1741494	D	Similar to RIBD_AQUAE Riboflavin biosynthesis protein ribD from Aquiflex aeolicus (356 aa). FASTA: opt: 915 z-score: 1060.1 E(): 3.4e-51 Smith-Waterman score: 916; 43.824 identity in 340 aa overlap; riboflavin biosynthesis protein ribD	1740427..1741494	Francisella tularensis subsp. tularensis FSC198	4199215
YP_667711.1	CDS	ribB	NC_008245.1	1741487	1742092	D	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha	1741487..1742092	Francisella tularensis subsp. tularensis FSC198	4199214
YP_667712.1	CDS	ribA	NC_008245.1	1742085	1743296	D	Similar to GCH2_AQUAE Riboflavin biosynthesis protein ribA from Aquiflex aeolicus (406 aa). FASTA: opt: 1135 z-score: 1316.5 E(): 1.8e-65 Smith-Waterman score: 1135; 46.305 identity in 406 aa overlap; riboflavin biosynthesis protein ribA/GTP-cyclohydrolase II	1742085..1743296	Francisella tularensis subsp. tularensis FSC198	4199213
YP_667713.1	CDS	ribH	NC_008245.1	1743306	1743749	D	Similar to AAO90192 (Q83DP8) Riboflavin synthase,beta subunit from Coxiella burnetii (151 aa). FASTA: opt: 496 z-score: 645.4 E(): 4.2e-28 Smith-Waterman score: 496; 53.571 identity in 140 aa overlap; riboflavin synthase beta subunit (6,7-dimethl-8-ribityllumazine synthase)	1743306..1743749	Francisella tularensis subsp. tularensis FSC198	4199217
YP_667714.1	CDS	def2	NC_008245.1	1743746	1744270	D	Similar to DEF_NEIMA (Q9JQN0) Peptide deformylase from Neisseria meningitidis (167 aa). FASTA: opt: 465 z-score: 571.7 E(): 5.4e-24 Smith-Waterman score: 465; 46.914 identity in 162 aa overlap; peptide deformylase	1743746..1744270	Francisella tularensis subsp. tularensis FSC198	4199343
YP_667715.1	CDS	FTF1676	NC_008245.1	1744352	1745344	D	ORF ftt1676; hypothetical protein	1744352..1745344	Francisella tularensis subsp. tularensis FSC198	4199835
YP_667716.1	CDS	mnmA	NC_008245.1	1745364	1746509	R	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA	complement(1745364..1746509)	Francisella tularensis subsp. tularensis FSC198	4199865
YP_667717.1	CDS	lepA	NC_008245.1	1746457	1748241	R	binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA	complement(1746457..1748241)	Francisella tularensis subsp. tularensis FSC198	4199511
YP_667718.1	CDS	rpsT	NC_008245.1	1748511	1748783	D	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20	1748511..1748783	Francisella tularensis subsp. tularensis FSC198	4198958
YP_667719.1	CDS	olmA	NC_008245.1	1748857	1749213	R	Similar to Q8KTI1 Outer membrane lipoprotein OmlA from Azaobacter vinelandii (171 aa). FASTA: opt: 208 Z-score: 273.7 E(): 2.1e-07 Smith-Waterman score: 208; 30.392 identity in 102 aa overlap; outer membrane lipoprotein	complement(1748857..1749213)	Francisella tularensis subsp. tularensis FSC198	4200762
YP_667720.1	CDS	lpcA	NC_008245.1	1749221	1749817	R	Similar to Q8EK08 Phosphoheptose isomerase from Shewanella oneidensis (197 aa). FASTA: opt: 705 z-score: 847.8 E(): 2.3e-39 Smith-Waterman score: 705; 53.684 identity in 190 aa overlap; phosphoheptose isomerase	complement(1749221..1749817)	Francisella tularensis subsp. tularensis FSC198	4199563
YP_667721.1	CDS	FTF1683c	NC_008245.1	1752366	1753517	R	Similar to Q8NM37 Permeases of the major facilitator superfamily from Corynebacterium glutamicum (398 aa). FASTA: opt: 440 z-score: 489.8 E(): 2e-19 Smith-Waterman score: 440; 24.211 identity in 380 aa overlap ORF ftt1683c; major facilitator transporter	complement(1752366..1753517)	Francisella tularensis subsp. tularensis FSC198	4200153
YP_667722.1	CDS	FTF1684	NC_008245.1	1753614	1754516	D	Similar to Q8D3N4 Transcriptional regulator from Vibrio vulnificus (307 aa). FASTA: opt: 510 Z-score: 590.3 E(): 5e-25 32.975 identity in 279 aa overlap ORF ftt1684; transcriptional regulator	1753614..1754516	Francisella tularensis subsp. tularensis FSC198	4200154
YP_667723.1	CDS	FTF1685	NC_008245.1	1754718	1755443	D	ORF ftt1685; hypothetical protein	1754718..1755443	Francisella tularensis subsp. tularensis FSC198	4200155
YP_667724.1	CDS	FTF1686c	NC_008245.1	1755597	1756265	R	Similar to Q894C5 Proline synthetase associated protein from Clostridium tetani (225 aa). FASTA: opt: 462 z-score: 549.8 E(): 8.9e-23 37.220 identity in 223 aa overlap ORF ftt1686c; hypothetical protein	complement(1755597..1756265)	Francisella tularensis subsp. tularensis FSC198	4200156
YP_667725.1	CDS	gidB	NC_008245.1	1756262	1756879	R	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB	complement(1756262..1756879)	Francisella tularensis subsp. tularensis FSC198	4199781
YP_667726.1	CDS	FTF1688	NC_008245.1	1756979	1758184	D	Similar to Q8EFB8 Tyrosine-specific transport protein from Shewanella oneidensis (395 aa). FASTA: opt: 854 z-score: 967.0 E(): 5.2e-46 38.378 identity in 370 aa overlap ORF ftt1688; aromatic amino acid HAAP transporter	1756979..1758184	Francisella tularensis subsp. tularensis FSC198	4200157
YP_667727.1	CDS	FTF1689c	NC_008245.1	1758181	1758873	R	Similar to CAD84514 (Q82WQ9) Possible transmembrane protein from Nitrosomonas europaea (223 aa). FASTA: opt: 294 z-score: 358.6 E(): 4e-12 25.481 identity in 208 aa overlap ORF ftt1689c; hypothetical protein	complement(1758181..1758873)	Francisella tularensis subsp. tularensis FSC198	4200158
YP_667728.1	CDS	FTF1690	NC_008245.1	1759277	1759942	D	Similar to Q9ABA7 NADH dehydrogenase from Caulobacter crescentus (220 aa). FASTA: opt: 429 z-score: 535.0 E(): 6e-22 35.545 identity in 211 aa overlap ORF ftt1690; NADH dehydrogenase	1759277..1759942	Francisella tularensis subsp. tularensis FSC198	4200159
YP_667729.1	CDS	FTF1691	NC_008245.1	1760213	1760737	D	This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein. ORF ftt1691; hypothetical protein	1760213..1760737	Francisella tularensis subsp. tularensis FSC198	4200160
YP_667730.1	CDS	isftu1	NC_008245.1	1760761	1761545	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(1760761..1761087,1761087..1761545)	Francisella tularensis subsp. tularensis FSC198	4200183
YP_667731.1	CDS	FTF1693c	NC_008245.1	1761688	1762452	R	Similar to Q87SC0 conserved hypothetical protein from Vibrio parahaemolyticus (258 aa). FASTA: opt: 724 z-score: 845.1 E(): 3.2e-39 46.094 identity in 256 aa overlap ORF ftt1693c; hypothetical protein	complement(1761688..1762452)	Francisella tularensis subsp. tularensis FSC198	4200161
YP_667732.1	CDS	FTF1694c	NC_008245.1	1763093	1763527	R	Similar to Q8ZCK6 Putative membrane protein (Hypothetical) from Yersinia pestis (175 aa). FASTA: opt:353 z-score 450 E():2.9e-17 35.9identity in 142 aa overlap ORF ftt1694c; hypothetical protein	complement(1763093..1763527)	Francisella tularensis subsp. tularensis FSC198	4200162
YP_667733.1	CDS	groES	NC_008245.1	1763778	1764065	D	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES	1763778..1764065	Francisella tularensis subsp. tularensis FSC198	4200299
YP_667734.1	CDS	groEL	NC_008245.1	1764103	1765737	D	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL	1764103..1765737	Francisella tularensis subsp. tularensis FSC198	4200298
YP_667735.1	CDS	isftu1	NC_008245.1	1765953	1766737	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(1765953..1766411,1766411..1766737))	Francisella tularensis subsp. tularensis FSC198	4200184
YP_667736.1	CDS	fdh	NC_008245.1	1766795	1767511	R	Similar to FDH_PSESR Formate dehydrogenase from Pseudomonas sp. (strain 101) (400 aa). FASTA: opt: 1074 z-score: 1253.7, E(): 5.5e-62, 66.949 identity in 236 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein.; formate dehydrogenase	complement(1766795..1767511)	Francisella tularensis subsp. tularensis FSC198	4199406
YP_667737.1	CDS	pdpA2	NC_008245.1	1773101	1775563	D	Similar to AAP58968.1 (Q7X3I9) PdpA from Francisella novicida (820 aa). BLAST Score = 1545 bits (4000), Expect = 0.0 Identities = 777/820 (94), Positives = 787/820 (95). Identical to FTF1344. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281; hypothetical protein	1773101..1775563	Francisella tularensis subsp. tularensis FSC198	4199231
YP_667738.1	CDS	pdpB2	NC_008245.1	1775568	1778849	D	Similar to AAP58967.1 (Q7X3J0) PdpB from Francisella novicida (1093 aa). BLAST Score = 1914 bits (4959), Expect = 0.0 Identities = 975/1093 (89),Positives = 988/1093 (90). This protein is identical to FTF1345. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..140828; hypothetical protein	1775568..1778849	Francisella tularensis subsp. tularensis FSC198	4199233
YP_667739.1	CDS	FTF1701	NC_008245.1	1778839	1779216	D	Identical to FTF1346. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1701; hypothetical protein	1778839..1779216	Francisella tularensis subsp. tularensis FSC198	4200163
YP_667740.1	CDS	FTF1702	NC_008245.1	1779229	1779723	D	Similar to AAP58969.1 (Q7XI38) unknown protein from Francisella novicida (164 aa). BLAST Score = 305 bits (780), Expect = 2e-82 Identities = 163/164 (99),Positives = 163/164 (99). Identical to FTF1347. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1702; hypothetical protein	1779229..1779723	Francisella tularensis subsp. tularensis FSC198	4200164
YP_667741.1	CDS	FTF1703	NC_008245.1	1779728	1781458	D	1-213 aa similar to AAP58970.1 (Q7X3I7) unknown Francisella novicida (212 aa). BLAST Score 352 ,Expect = 1e-95 Identities = 177/209 (84), Positives = 189/209 (90). 330-580 aa similar to AAP58971.1 (Q7X3I6) unknown protein from Francisella tularensis subsp. novicida (251 aa). BLAST Score = 483 bits (1244), Expect = e-135 Identities = 243/251 (96), Positives = 249/251 (99). Identical to FTF1348. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281. Protein fusion product of two hypothetical proteins in F. novicida. ORF ftt1703; hypothetical protein	1779728..1781458	Francisella tularensis subsp. tularensis FSC198	4200165
YP_667742.1	CDS	FTF1704	NC_008245.1	1781459	1781980	D	Similar to AAP58972.1 (Q7X3I5) unknown protein from Francisella novicida (173 aa). BLAST Score = 336, Expect = 1e-91 Identities = 170/173 (98), Positives = 171/173 (98). Identical to FTF1349. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1704; hypothetical protein	1781459..1781980	Francisella tularensis subsp. tularensis FSC198	4200166
YP_667743.1	CDS	FTF1705	NC_008245.1	1781993	1783423	D	Similar to AAP58973.1 (Q7X3I4) unknown protein from Francisella novicida (476 aa). BLAST Score = 864 bits (2233), Expect = 0.0 Identities = 433/476 (90),Positives = 437/476 (91). Identical to FTF1350. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1705; hypothetical protein	1781993..1783423	Francisella tularensis subsp. tularensis FSC198	4200167
YP_667744.1	CDS	FTF1706	NC_008245.1	1783436	1784059	D	Similar to AAP58974.1 (Q7X3I3) unknown protein from Francisella novicida (207 aa). BLAST Score = 391 bits (1005), Expect = e-108 Identities = 194/207 (93),Positives = 195/207 (94). Identical to FTF1351. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1706; hypothetical protein	1783436..1784059	Francisella tularensis subsp. tularensis FSC198	4200168
YP_667745.1	CDS	FTF1707	NC_008245.1	1784081	1785232	D	Similar to AAP58975.1 (Q7X3I2) unknown protein from Francisella novicida (262 aa), BLAST Score = 443 bits (1140), Expect = e-12 Identities = 229/262 (87),Positives = 235/262 (89). Identical to FTF1352. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1707; hypothetical protein	1784081..1785232	Francisella tularensis subsp. tularensis FSC198	4200169
YP_667746.1	CDS	FTF1708	NC_008245.1	1785198	1785971	D	Similar to AAP58976.1 (Q7X3I1) unknown protein from Francisella novicida (257 aa). BLAST Score = 412, Expect = e-114 Identities = 213/257 (82), Positives = 213/257 (82). Identical to FTF1353. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1708; hypothetical protein	1785198..1785971	Francisella tularensis subsp. tularensis FSC198	4200170
YP_667747.1	CDS	pdpC2	NC_008245.1	1786011	1789997	D	Similar to AAP58966.1 PdpC from Francisella novicida (1218 aa). BLAST Score = 2172, Expect = 0.0 Identities = 1089/1220 (89), Positives = 1120/1220 (91),Gaps = 3/1220 (0). Identical to FTF1354. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281; hypothetical protein	1786011..1789997	Francisella tularensis subsp. tularensis FSC198	4199235
YP_667748.1	CDS	FTF1710	NC_008245.1	1790015	1790590	D	Similar to AAP58977.1 (Q7X3I0) unknown protein from Francisella novicida (188 aa). BLAST Score = 321, Expect = 3e-87 Identities = 156/174 (89), Positives = 162/174 (93). Identical to FTF1355. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1710; hypothetical protein	1790015..1790590	Francisella tularensis subsp. tularensis FSC198	4200171
YP_667749.1	CDS	iglD2	NC_008245.1	1790597	1791802	R	Similar to AAP58965.1 (Q7C3J6) IglD from Francisella novicida (398 aa). BLAST Score = 746, Expect = 0.0 Identities = 382/398 (95), Positives = 383/398 (96) Identical to FTF1356. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281; intracellular growth locus, subunit D	complement(1790597..1791802)	Francisella tularensis subsp. tularensis FSC198	4200660
YP_667750.1	CDS	iglC2	NC_008245.1	1791814	1792449	R	Similar to AAP58964.1 (Q7X3J5) IglC from Francisella novicida (23 kDa protein) (211 aa). BLAST Score = 405,Expect = e-112 Identities = 209/211 (99),Positives = 210/211 (99). Identical to FTF1357. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281; intracellular growth locus, subunit C	complement(1791814..1792449)	Francisella tularensis subsp. tularensis FSC198	4200658
YP_667751.1	CDS	iglB2	NC_008245.1	1792460	1794004	R	Similar to AAP58963.1 (Q7X3J4) IglB from Francisella novicida (514 aa). BLAST Score = 997, Expect = 0.0 Identities = 496/514 (96), Positives = 499/514 (97). Identical to FTF1358. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281; intracellular growth locus, subunit B	complement(1792460..1794004)	Francisella tularensis subsp. tularensis FSC198	4200656
YP_667752.1	CDS	iglA2	NC_008245.1	1793994	1794584	R	Similar to AAP58962.1 (Q7X3J5) IglA from Francisella novicida (184 aa). BLAST Score = 350, Expect = 6e-96 Identities = 181/184 (98), Positives = 181/184 (98). Identical to FTF1359. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281; intracellular growth locus, subunit A	complement(1793994..1794584)	Francisella tularensis subsp. tularensis FSC198	4200654
YP_667753.1	CDS	pdpD2	NC_008245.1	1794629	1798216	R	Similar to AAP58961.1 (Q7C3J6) PdpD from Francisella novicida (1245 aa). BLAST Score = 2194, Expect = 0.0 Identities = 1133/1245 (91), Positives = 1154/1245 (92), Gaps = 50/1245 (4). Identical to FTF1360. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281; hypothetical protein	complement(1794629..1798216)	Francisella tularensis subsp. tularensis FSC198	4199237
YP_667754.1	CDS	isftu1	NC_008245.1	1800572	1801356	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(1800572..1801030,1801030..1801356))	Francisella tularensis subsp. tularensis FSC198	4200185
YP_667755.1	CDS	purL	NC_008245.1	1801914	1805786	R	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase	complement(1801914..1805786)	Francisella tularensis subsp. tularensis FSC198	4199121
YP_667756.1	CDS	purF	NC_008245.1	1805786	1807276	R	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase	complement(1805786..1807276)	Francisella tularensis subsp. tularensis FSC198	4199118
YP_667757.1	CDS	gad	NC_008245.1	1807370	1808716	R	Similar to Q8FHG5 Glutamate decarboxylase beta from E. coli (489 aa). FASTA: opt: 1709 Z-score: 1968.5 bits: 373.6 E(): 8.6e-102 Smith-Waterman score: 1709; 57.011 identity in 435 aa overlap; glutamate decarboxylase	complement(1807370..1808716)	Francisella tularensis subsp. tularensis FSC198	4199207
YP_667758.1	CDS	FTF1723c	NC_008245.1	1808727	1809371	R	Similar to GSP_BACBR (P40683) 4'-phosphopantetheinyl transferase from Bacillus brevis (237 aa). FASTA: opt: 224 Z-score: 292.3 E(): 2.2e-08 Smith-Waterman score: 224; 33.929 identity in 112 aa overlap ORF ftt1723c; hypothetical protein	complement(1808727..1809371)	Francisella tularensis subsp. tularensis FSC198	4199896
YP_667759.1	CDS	tolC	NC_008245.1	1809377	1810906	R	Similar to TOLC_ECOLI (P02930) Outer membrane protein tolC precursor from E. coli (495 aa). FASTA: opt: 548 Z-score: 649.7 E(): 2.7e-28 Smith-Waterman score: 548; 28.000 identity in 425 aa overlap; outer membrane protein tolC	complement(1809377..1810906)	Francisella tularensis subsp. tularensis FSC198	4199150
YP_667760.1	CDS	pcm	NC_008245.1	1810915	1811535	R	Similar to Q9JXU0 Protein-L-isoaspartate O-methyltransferase from Neisseria meningitidis (218 aa). FASTA: opt: 335 Z-score: 438.9 E(): 1.5e-16 Smith-Waterman score: 335; 33.659 identity in 205 aa overlap; protein-L-isoaspartate O-methyltransferase	complement(1810915..1811535)	Francisella tularensis subsp. tularensis FSC198	4200098
YP_667761.1	CDS	yegQ	NC_008245.1	1811855	1813186	D	Similar to YEGQ_ECOLI (P76403) Putative protease yegQ from E. coli (453 aa). FASTA: opt: 1828 Z-score: 2215.7 E(): 1.6e-115 Smith-Waterman score: 1828; 61.745identity in 447 aa overlap Truncated ortholog (188 aa) previously reported in Schu as O68834 Hypothetical 21.3 kDa protein and AAC12939 unknown; protease yegQ	1811855..1813186	Francisella tularensis subsp. tularensis FSC198	4199097
YP_667762.1	CDS	FTF1727c	NC_008245.1	1813227	1814417	R	Similar to Q83CE1 Drug resistance transporter,Bcr/CflA family from Coxiella burnetii (398 aa). FASTA: opt: 957 Z-score: 1006.0 E(): 3.8e-48 Smith-Waterman score: 957; 38.542identity in 384 aa overlap ORF ftt1727c; multidrug resistance protein, membrane located	complement(1813227..1814417)	Francisella tularensis subsp. tularensis FSC198	4199897
YP_667763.1	CDS	nhaD	NC_008245.1	1814583	1816010	D	Similar to Q8D4S6 Na+/H+ antiporter NhaD from Vibrio vulnificus (478 aa). FASTA: opt: 1428 Z-score: 1679.2 E(): 1.2e-85 Smith-Waterman score: 1592; 50.617identity in 486 aa overlap; Na+/H+ antiporter	1814583..1816010	Francisella tularensis subsp. tularensis FSC198	4200241
YP_667764.1	CDS	FTF1730c	NC_008245.1	1817661	1819535	R	Similar to Q97MC6 Amino acid transporter from Clostridium acetobutylicum (620 aa). FASTA: opt: 1338 Z-score: 1514.2 E(): 1.9e-76 Smith-Waterman score: 1338; 37.745 identity in 612 aa overlap ORF ftt1730c; amino acid transporter	complement(1817661..1819535)	Francisella tularensis subsp. tularensis FSC198	4199898
YP_667765.1	CDS	obgE	NC_008245.1	1819542	1820546	R	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE	complement(1819542..1820546)	Francisella tularensis subsp. tularensis FSC198	4199899
YP_667766.1	CDS	FTF1732c	NC_008245.1	1820622	1821818	R	Similar to Q8FGM8 Tyrosine-specific transport protein from E. coli (403 aa). FASTA: opt: 724 Z-score: 839.2 E(): 6.8e-39 Smith-Waterman score: 724; 35.638 identity in 376 aa overlap ORF ftt1732; aromatic amino acid HAAP transporter	complement(1820622..1821818)	Francisella tularensis subsp. tularensis FSC198	4199900
YP_667767.1	CDS	FTF1733	NC_008245.1	1821945	1822256	D	ORF ftt1733; hypothetical protein	1821945..1822256	Francisella tularensis subsp. tularensis FSC198	4199901
YP_667768.1	CDS	kdpD	NC_008245.1	1823837	1826518	R	Similar to Q8U9E1 Two component sensor kinase from Agrobacterium tumefaciens (900 aa). FASTA: opt: 1625 Z-score: 1777.7 E(): 3.6e-91 Smith-Waterman score: 1625; 32.745 identity in 907 aa overlap; two component sensor protein kdpD	complement(1823837..1826518)	Francisella tularensis subsp. tularensis FSC198	4199504
YP_667769.1	CDS	kdpC	NC_008245.1	1826622	1827176	R	Similar to Q8R8I7 K+-transporting ATPase, c chain from Thermoanaerobacter tengcogenesis (193 aa). FASTA: opt: 404 Z-score: 471.4 E(): 2.1e-18 Smith-Waterman score: 404; 43.333identity in 180 aa overlap; potassium-transporting ATPase C chain	complement(1826622..1827176)	Francisella tularensis subsp. tularensis FSC198	4199503
YP_667770.1	CDS	kdpB	NC_008245.1	1827193	1829232	R	Similar to ATKB_RHIME (Q92XJ0) Potassium-transporting ATPase B chain from Rhizobium meliloti (680 aa). FASTA: opt: 2393 Z-score: 2638.7 E(): 4.4e-139 Smith-Waterman score: 2393; 55.490 identity in 683 aa overlap; potassium-transporting ATPase B chain	complement(1827193..1829232)	Francisella tularensis subsp. tularensis FSC198	4199502
YP_667771.1	CDS	isftu1	NC_008245.1	1831691	1832475	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(1831691..1832149,1832149..1832475))	Francisella tularensis subsp. tularensis FSC198	4200186
YP_667772.1	CDS	ipdC	NC_008245.1	1833212	1834909	R	Similar to Q8TT45 Indolepyruvate decarboxylase Methanosarcina activorans (550 aa). FASTA: opt: 1265 Z-score: 1467.5 E(): 7.6e-74 Smith-Waterman score: 1265; 36.909 identity in 550 aa overlap; indolepyruvate decarboxylase	complement(1833212..1834909)	Francisella tularensis subsp. tularensis FSC198	4199612
YP_667773.1	CDS	FTF1746	NC_008245.1	1835440	1836363	D	Similar to Q87YG1 Signal peptide peptidase SppA,36K type from Pseudomonas syringae (332 a). FASTA: opt: 839 Z-score: 1007.2 E(): 3.3e-48 Smith-Waterman score: 839; 46.622 identity in 296 aa overlap ORF ftt1746; peptidase	1835440..1836363	Francisella tularensis subsp. tularensis FSC198	4199906
YP_667774.1	CDS	FTF1747	NC_008245.1	1836417	1836992	D	Similar to AAO90156 (Q83DT1) Outer membrane protein OmpH, putative, from Coxiella burnetii (165 aa). FASTA: opt: 175 Z-score: 183.6 E(): 0.022 Smith-Waterman score: 216; 26.816 identity in 179 aa overlap ORF ftt1747; outer membrane protein	1836417..1836992	Francisella tularensis subsp. tularensis FSC198	4199907
YP_667775.1	CDS	glpe	NC_008245.1	1837128	1837550	D	Similar to AAO91018 (Q83BI7) Rhodanese domain protein Coxiella burnetii (144 aa). FASTA: opt: 279 Z-score: 342.5 E(): 3.5e-11 Smith-Waterman score: 279; 33.094 identity in 139 aa overlap; thiosulfate sulfurtransferase	1837128..1837550	Francisella tularensis subsp. tularensis FSC198	4199794
YP_667776.1	CDS	secB1	NC_008245.1	1837577	1838026	D	molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB	1837577..1838026	Francisella tularensis subsp. tularensis FSC198	4200734
YP_667777.1	CDS	recA	NC_008245.1	1838048	1839127	D	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A	1838048..1839127	Francisella tularensis subsp. tularensis FSC198	4200599
YP_667778.1	CDS	recX	NC_008245.1	1839114	1839566	D	Similar to RECX_HAEIN (P43706) Regulatory protein recX from Haemophilus influenzae (126 aa). FASTA: opt: 243 Z-score: 314.3 E(): 1.3e-09 Smith-Waterman score: 243; 31.967 identity in 122 aa overlap; regulatory protein recX	1839114..1839566	Francisella tularensis subsp. tularensis FSC198	4200608
YP_667779.1	CDS	ssb	NC_008245.1	1839739	1840215	D	Similar to SSB_HAEIN P44409 Single-strand binding protein (SSB) from Haemophilus influenzae (168 aa). FASTA: opt: 437 Z-score: 543.8 E(): 1.9e-22 Smith-Waterman score: 437; 44.578identity in 166 aa overlap; single-strand binding protein	1839739..1840215	Francisella tularensis subsp. tularensis FSC198	4199084
YP_667780.1	CDS	tdcD	NC_008245.1	1840321	1841475	D	Similar to ACKA_CLOTS (Q59331) Acetate kinase (Acetokinase) from Clostridium thermosaccharolyticum (400 aa). FASTA: opt: 1204 Z-score: 1394.5 E(): 8e-70 Smith-Waterman score: 1204; 49.873 identity in 395 aa overlap; propionate kinase	1840321..1841475	Francisella tularensis subsp. tularensis FSC198	4199134
YP_667781.1	CDS	pta	NC_008245.1	1841485	1843581	D	catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase	1841485..1843581	Francisella tularensis subsp. tularensis FSC198	4199947
YP_667782.1	CDS	isftu1	NC_008245.1	1844589	1845373	R	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	complement(join(1844589..1845047,1845047..1845373))	Francisella tularensis subsp. tularensis FSC198	4200187
YP_667783.1	CDS	FTF1758c	NC_008245.1	1846810	1847403	R	Similar to Q8D0W2 Putative cytochrome from Yersinia pestis (199 aa). FASTA: opt: 273 Z-score: 328.7 E(): 1.9e-10 Smith-Waterman score: 273; 27.979identity in 193 aa overlap ORF ftt1758c; B-type cytochrome	complement(1846810..1847403)	Francisella tularensis subsp. tularensis FSC198	4199909
YP_667784.1	CDS	nhaA	NC_008245.1	1848371	1849522	D	exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter	1848371..1849522	Francisella tularensis subsp. tularensis FSC198	4200240
YP_667785.1	CDS	FTF1761	NC_008245.1	1849587	1850306	D	Similar to YAFD_ECOLI (P30865) Hypothetical protein yafD from E. coli (266 aa). FASTA: opt: 320 Z-score: 403.2 E(): 1.5e-14 Smith-Waterman score: 320; 34.498 identity in 229 aa overlap ORF ftt1761; hypothetical protein	1849587..1850306	Francisella tularensis subsp. tularensis FSC198	4199911
YP_667786.1	CDS	FTF1762c	NC_008245.1	1850312	1851052	R	Similar to Q9F728 Putative N-acylhomoserine lactone synthase from Pseudomonas fluorescens (259 aa). FASTA: opt: 408 Z-score: 521.4 E(): 3.8e-21 Smith-Waterman score: 408; 34.498 identity in 229 aa overlap ORF ftt1762c; acetyltransferase protein	complement(1850312..1851052)	Francisella tularensis subsp. tularensis FSC198	4199535
YP_667787.1	CDS	FTF1763c	NC_008245.1	1851066	1851818	R	Similar to Q9F728 Putative N-acylhomoserine lactone syntase from Pseudomonas fluorescens (259 aa). FASTA: opt: 442 Z-score: 546.9 E(): 1.4e-22 Smith-Waterman score: 442; 37.963 identity in 216 aa overlap. ORF ftt1763c; acetyltransferase protein	complement(1851066..1851818)	Francisella tularensis subsp. tularensis FSC198	4199536
YP_667788.1	CDS	FTF1764c	NC_008245.1	1851981	1852304	R	Similar to FER_PSEST (P08811) Ferredoxin from Pseudomonas stutzeri (106 aa). FASTA: opt: 535 Z-score: 674.6 E(): 1.1e-29 Smith-Waterman score: 535; 65.714identity in 105 aa overlap ORF ftt1764c; ferredoxin	complement(1851981..1852304)	Francisella tularensis subsp. tularensis FSC198	4199537
YP_667789.1	CDS	FTF1765	NC_008245.1	1852524	1853177	D	ORF ftt1765; hypothetical protein	1852524..1853177	Francisella tularensis subsp. tularensis FSC198	4199538
YP_667790.1	CDS	FTF1766	NC_008245.1	1853255	1853911	D	Similar to Q8YLW7 O-methyltransferase from Anabaena sp. (220 aa). FASTA: opt: 622 Z-score: 791.6 E(): 3.4e-36 Smith-Waterman score: 622; 43.836identity in 219 aa overlap ORF ftt1766; O-methyltransferase	1853255..1853911	Francisella tularensis subsp. tularensis FSC198	4199539
YP_667791.1	CDS	purT	NC_008245.1	1853913	1855073	R	non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2	complement(1853913..1855073)	Francisella tularensis subsp. tularensis FSC198	4199124
YP_667792.1	CDS	FTF1768c	NC_008245.1	1855127	1856947	R	Similar to Q9KQP6 Chitinase from Vibrio cholerae (846 aa). FASTA: opt: 242 Z-score: 272.3 E(): 2.8e-07 Smith-Waterman score: 279; 21.309 identity in 718 aa overlap. ORF ftt1768c; chitinase	complement(1855127..1856947)	Francisella tularensis subsp. tularensis FSC198	4199540
YP_667793.1	CDS	clpB	NC_008245.1	1857569	1860148	R	Similar to FASTA: AAO89660 (Q83F55) ClpB protein from Coxiella burnetii (859 aa). FASTA: opt: 3593 Z-score: 3223.6 E(): 1.1e-171 Smith-Waterman score: 3593; 65.357 identity in 840 aa overlap; ClpB protein	complement(1857569..1860148)	Francisella tularensis subsp. tularensis FSC198	4200323
YP_667794.1	CDS	FTF1771	NC_008245.1	1861167	1861520	D	ORF ftt1771; hypothetical protein	1861167..1861520	Francisella tularensis subsp. tularensis FSC198	4199542
YP_667795.1	CDS	trpA	NC_008245.1	1861575	1862384	R	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha	complement(1861575..1862384)	Francisella tularensis subsp. tularensis FSC198	4200716
YP_667796.1	CDS	trpB	NC_008245.1	1862384	1863574	R	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta	complement(1862384..1863574)	Francisella tularensis subsp. tularensis FSC198	4200717
YP_667797.1	CDS	clcA	NC_008245.1	1864990	1866519	R	Similar to CLCA_ECOLI (P37019) Voltage-gated ClC-type chloride channel from E. coli (473 aa). FASTA: opt: 1120 Z-score: 1211.7 E(): 1.3e-59 Smith-Waterman score: 1120; 39.545 identity in 440 aa overlap; voltage-gated ClC-type chloride channel clcA	complement(1864990..1866519)	Francisella tularensis subsp. tularensis FSC198	4200322
YP_667798.1	CDS	FTF1776c	NC_008245.1	1866590	1866988	R	ORF ftt1776c; hypothetical protein	complement(1866590..1866988)	Francisella tularensis subsp. tularensis FSC198	4199544
YP_667799.1	CDS	FTF1777c	NC_008245.1	1866991	1867401	R	ORF ftt1777c; hypothetical protein	complement(1866991..1867401)	Francisella tularensis subsp. tularensis FSC198	4199545
YP_667800.1	CDS	FTF1778c	NC_008245.1	1867422	1867814	R	ORF ftt1778c; hypothetical protein	complement(1867422..1867814)	Francisella tularensis subsp. tularensis FSC198	4199546
YP_667801.1	CDS	isftu1	NC_008245.1	1868647	1869431	D	ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs.; transposase	join(1868647..1868973,1868973..1869431)	Francisella tularensis subsp. tularensis FSC198	4200188
YP_667802.1	CDS	FTF1781c	NC_008245.1	1869670	1870419	R	ORF ftt1781c; hypothetical protein	complement(1869670..1870419)	Francisella tularensis subsp. tularensis FSC198	4199548
YP_667803.1	CDS	yjjK	NC_008245.1	1870361	1872040	R	ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein	complement(1870361..1872040)	Francisella tularensis subsp. tularensis FSC198	4199031
YP_667804.1	CDS	FTF1783	NC_008245.1	1872208	1873494	D	Similar to Q83A52 Major facilitator family transporter from Coxiella burnetii (443 aa). FASTA: opt: 751 Z-score: 809.6 E(): 3.3e-37 Smith-Waterman score: 751; 34.204identity in 421 aa overlap ORF ftt1783; major facilitator transporter	1872208..1873494	Francisella tularensis subsp. tularensis FSC198	4199549
YP_667805.1	CDS	FTF1784c	NC_008245.1	1873475	1873783	R	ORF ftt1784c; hypothetical protein	complement(1873475..1873783)	Francisella tularensis subsp. tularensis FSC198	4199550
YP_667806.1	CDS	FTF1785c	NC_008245.1	1873795	1874007	R	ORF ftt1785c; hypothetical protein	complement(1873795..1874007)	Francisella tularensis subsp. tularensis FSC198	4199551
YP_667807.1	CDS	FTF1787c	NC_008245.1	1875041	1875652	R	Similar to Q8UGV8 LysE family transporter from Agrobactium tumifaciens (202 aa). FASTA: opt: 346 Z-score: 414.9 E(): 3.2e-15 Smith-Waterman score: 346; 30.102 identity in 196 aa overlap ORF ftt1787c; amino acid transporter LysE	complement(1875041..1875652)	Francisella tularensis subsp. tularensis FSC198	4199988
YP_667808.1	CDS	FTF1789	NC_008245.1	1876953	1877747	D	Similar to Q83C04 Membrane protein, putative, from Coxiella burnetii (263 aa). FASTA: opt: 496 Z-score: 540.4 E(): 3.3e-22 Smith-Waterman score: 496; 30.038 identity in 263 aa overlap ORF ftt1789; hypothetical protein	1876953..1877747	Francisella tularensis subsp. tularensis FSC198	4199989
YP_667809.1	CDS	FTF1791	NC_008245.1	1878156	1878518	D	ORF ftt1791; hypothetical protein	1878156..1878518	Francisella tularensis subsp. tularensis FSC198	4199991
YP_667810.1	CDS	pepN	NC_008245.1	1879650	1882244	R	Similar to AMPN_ECOLI (P04825) Aminopeptidase N from E. coli (869 aa). FASTA: opt: 2226 Z-score: 2532.9 E(): 3.4e-133 Smith-Waterman score: 2751; 48.856identity in 874 aa overlap; aminopeptidase N	complement(1879650..1882244)	Francisella tularensis subsp. tularensis FSC198	4199240
YP_667811.1	CDS	FTF1794	NC_008245.1	1882428	1882856	D	Similar to Q9WYK7 Heat shock protein, class I from Thermatoga maritima (147 aa). FASTA: opt: 288 Z-score: 346.4 E(): 2.1e-11 Smith-Waterman score: 288; 37.879 identity in 132 aa overlap ORF ftt1794; heat shock protein	1882428..1882856	Francisella tularensis subsp. tularensis FSC198	4199993
YP_667812.1	CDS	trpC	NC_008245.1	1882853	1884214	R	monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase	complement(1882853..1884214)	Francisella tularensis subsp. tularensis FSC198	4200718
YP_667813.1	CDS	FTF1796c	NC_008245.1	1884305	1884718	R	Similar to Q9KF27 Hypothetical protein BH0670 from Bacillus halodurans (159 aa). FASTA: opt: 208 Z-score: 278.0 E(): 1.4e-07 Smith-Waterman score: 208; 28.682 identity in 129 aa overlap ORF ftt1796c; hypothetical protein	complement(1884305..1884718)	Francisella tularensis subsp. tularensis FSC198	4199994
YP_667814.1	CDS	msrA2	NC_008245.1	1884723	1885412	R	Similar to MSA2_CAUCR (Q9A9E9) Peptide methionine sulfoxide reductase from Caulobacter crescentus (196 aa). FASTA opt: 510 Z-score: 598.2 E(): 2e-25 Smith-Waterman score: 510; 39.024 identity in 205 aa overlap; peptide methionine sulfoxide reductase MsrA	complement(1884723..1885412)	Francisella tularensis subsp. tularensis FSC198	4200101
YP_667815.1	CDS	FTF1798c	NC_008245.1	1885496	1885864	R	ORF ftt1798c; hypothetical protein	complement(1885496..1885864)	Francisella tularensis subsp. tularensis FSC198	4199995
YP_667816.1	CDS	FTF1800c	NC_008245.1	1886267	1886719	R	ORF ftt1800c; hypothetical protein	complement(1886267..1886719)	Francisella tularensis subsp. tularensis FSC198	4199997
YP_667817.1	CDS	trpE	NC_008245.1	1888373	1889917	R	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I	complement(1888373..1889917)	Francisella tularensis subsp. tularensis FSC198	4200719
YP_667818.1	CDS	trpR	NC_008245.1	1889926	1890213	R	Similar to TRPR_ECOLI (P03032) Trp operon repressor from E. coli (107 aa). FASTA: opt: 175 Z-score: 239.1 E(): 2e-05 Smith-Waterman score: 175; 32.584 identity in 89 aa overlap; trp operon repressor	complement(1889926..1890213)	Francisella tularensis subsp. tularensis FSC198	4200722
YP_667819.1	CDS	rng	NC_008245.1	1890687	1892183	R	Similar to RNG_ECOLI (P25537) Ribonuclease G from E. coli (488 aa). FASTA: opt: 1439 Z-score: 1642.1 E(): 1.4e-83 Smith-Waterman score: 1439; 45.418 identity in 491 aa overlap; ribonuclease G	complement(1890687..1892183)	Francisella tularensis subsp. tularensis FSC198	4200765
FTFt01	tRNA	FTFt01	NC_008245.1	48587	48660	D	tRNA-Met	48587..48660	Francisella tularensis subsp. tularensis FSC198	4199454
FTFt02	tRNA	FTFt02	NC_008245.1	84535	84617	D	tRNA-Leu	84535..84617	Francisella tularensis subsp. tularensis FSC198	4199450
FTFt03	tRNA	FTFt03	NC_008245.1	149754	149835	D	tRNA-Tyr	149754..149835	Francisella tularensis subsp. tularensis FSC198	4200712
FTFt04	tRNA	FTFt04	NC_008245.1	149840	149910	D	tRNA-Gly	149840..149910	Francisella tularensis subsp. tularensis FSC198	4199444
FTFt05	tRNA	FTFt05	NC_008245.1	149942	150014	D	tRNA-Thr	149942..150014	Francisella tularensis subsp. tularensis FSC198	4200709
FTFt06	tRNA	FTFt06	NC_008245.1	151266	151341	D	tRNA-Trp	151266..151341	Francisella tularensis subsp. tularensis FSC198	4200711
FTFt07	tRNA	FTFt07	NC_008245.1	287069	287143	D	tRNA-Gln	287069..287143	Francisella tularensis subsp. tularensis FSC198	4199440
FTFt08	tRNA	FTFt08	NC_008245.1	326575	326650	D	tRNA-Glu	326575..326650	Francisella tularensis subsp. tularensis FSC198	4199441
FTFt09	tRNA	FTFt09	NC_008245.1	722196	722268	D	tRNA-Val	722196..722268	Francisella tularensis subsp. tularensis FSC198	4200714
FTFt10	tRNA	FTFt10	NC_008245.1	774909	774993	R	tRNA-Ser	complement(774909..774993)	Francisella tularensis subsp. tularensis FSC198	4200708
FTFt11	tRNA	FTFt11	NC_008245.1	822845	822920	D	tRNA-Phe	822845..822920	Francisella tularensis subsp. tularensis FSC198	4199457
FTFt12	tRNA	FTFt12	NC_008245.1	822938	823014	D	tRNA-Pro	822938..823014	Francisella tularensis subsp. tularensis FSC198	4199458
FTFt13	tRNA	FTFt13	NC_008245.1	823023	823099	D	tRNA-Arg	823023..823099	Francisella tularensis subsp. tularensis FSC198	4199871
FTFt14	tRNA	FTFt14	NC_008245.1	823127	823199	D	tRNA-His	823127..823199	Francisella tularensis subsp. tularensis FSC198	4199445
FTFt15	tRNA	FTFt15	NC_008245.1	823209	823291	D	tRNA-Leu	823209..823291	Francisella tularensis subsp. tularensis FSC198	4199452
FTFt16	tRNA	FTFt16	NC_008245.1	864804	864890	D	tRNA-Ser	864804..864890	Francisella tularensis subsp. tularensis FSC198	4200707
FTFt17	tRNA	FTFt17	NC_008245.1	932641	932714	R	tRNA-Val	complement(932641..932714)	Francisella tularensis subsp. tularensis FSC198	4200713
FTFt18	tRNA	FTFt18	NC_008245.1	1310489	1310564	R	tRNA-Ala	complement(1310489..1310564)	Francisella tularensis subsp. tularensis FSC198	4199866
FTFt19	tRNA	FTFt19	NC_008245.1	1310582	1310655	R	tRNA-Ile	complement(1310582..1310655)	Francisella tularensis subsp. tularensis FSC198	4199446
FTFt20	tRNA	FTFt20	NC_008245.1	1313494	1313569	R	tRNA-Val	complement(1313494..1313569)	Francisella tularensis subsp. tularensis FSC198	4200715
FTFt21	tRNA	FTFt21	NC_008245.1	1313597	1313688	R	tRNA-Ser	complement(1313597..1313688)	Francisella tularensis subsp. tularensis FSC198	4199459
FTFt22	tRNA	FTFt22	NC_008245.1	1353783	1353858	R	tRNA-Lys	complement(1353783..1353858)	Francisella tularensis subsp. tularensis FSC198	4199453
FTFt23	tRNA	FTFt23	NC_008245.1	1377608	1377683	R	tRNA-Ala	complement(1377608..1377683)	Francisella tularensis subsp. tularensis FSC198	4199867
FTFt24	tRNA	FTFt24	NC_008245.1	1377701	1377774	R	tRNA-Ile	complement(1377701..1377774)	Francisella tularensis subsp. tularensis FSC198	4199447
FTFt25	tRNA	FTFt25	NC_008245.1	1451788	1451876	R	tRNA-Leu	complement(1451788..1451876)	Francisella tularensis subsp. tularensis FSC198	4199451
FTFt26	tRNA	FTFt26	NC_008245.1	1451882	1451955	R	tRNA-Cys	complement(1451882..1451955)	Francisella tularensis subsp. tularensis FSC198	4199874
FTFt27	tRNA	FTFt27	NC_008245.1	1451974	1452045	R	tRNA-Gly	complement(1451974..1452045)	Francisella tularensis subsp. tularensis FSC198	4199443
FTFt28	tRNA	FTFt28	NC_008245.1	1459298	1459370	D	tRNA-Asn	1459298..1459370	Francisella tularensis subsp. tularensis FSC198	4199872
FTFt29	tRNA	FTFt29	NC_008245.1	1488520	1488606	R	tRNA-Leu	complement(1488520..1488606)	Francisella tularensis subsp. tularensis FSC198	4199449
FTFt30	tRNA	FTFt30	NC_008245.1	1540957	1541033	D	tRNA-Arg	1540957..1541033	Francisella tularensis subsp. tularensis FSC198	4199869
FTFt31	tRNA	FTFt31	NC_008245.1	1541048	1541119	D	tRNA-Gly	1541048..1541119	Francisella tularensis subsp. tularensis FSC198	4199442
FTFt32	tRNA	FTFt32	NC_008245.1	1626589	1626665	D	tRNA-Met	1626589..1626665	Francisella tularensis subsp. tularensis FSC198	4199455
FTFt33	tRNA	FTFt33	NC_008245.1	1706031	1706104	D	tRNA-Met	1706031..1706104	Francisella tularensis subsp. tularensis FSC198	4199456
FTFt34	tRNA	FTFt34	NC_008245.1	1763008	1763083	R	tRNA-Arg	complement(1763008..1763083)	Francisella tularensis subsp. tularensis FSC198	4199870
FTFt35	tRNA	FTFt35	NC_008245.1	1770943	1771018	R	tRNA-Ala	complement(1770943..1771018)	Francisella tularensis subsp. tularensis FSC198	4199868
FTFt36	tRNA	FTFt36	NC_008245.1	1771036	1771109	R	tRNA-Ile	complement(1771036..1771109)	Francisella tularensis subsp. tularensis FSC198	4199448
FTFt37	tRNA	FTFt37	NC_008245.1	1890470	1890546	R	tRNA-Asp	complement(1890470..1890546)	Francisella tularensis subsp. tularensis FSC198	4199873
FTFt38	tRNA	FTFt38	NC_008245.1	1890551	1890626	R	tRNA-Thr	complement(1890551..1890626)	Francisella tularensis subsp. tularensis FSC198	4200710
FTFr01	rRNA	FTFr01	NC_008245.1	408789	408911	D	5S ribosomal RNA	408789..408911	Francisella tularensis subsp. tularensis FSC198	4200004
FTFr02	rRNA	FTFr02	NC_008245.1	1307389	1307505	R	5S ribosomal RNA	complement(1307389..1307505)	Francisella tularensis subsp. tularensis FSC198	4200005
FTFr03	rRNA	FTFr03	NC_008245.1	1307550	1310415	R	23S ribosomal RNA	complement(1307550..1310415)	Francisella tularensis subsp. tularensis FSC198	4200001
FTFr04	rRNA	FTFr04	NC_008245.1	1310748	1312277	R	16S ribosomal RNA	complement(1310748..1312277)	Francisella tularensis subsp. tularensis FSC198	4199998
FTFr05	rRNA	FTFr05	NC_008245.1	1374508	1374624	R	5S ribosomal RNA	complement(1374508..1374624)	Francisella tularensis subsp. tularensis FSC198	4199743
FTFr06	rRNA	FTFr06	NC_008245.1	1374669	1377534	R	23S ribosomal RNA	complement(1374669..1377534)	Francisella tularensis subsp. tularensis FSC198	4200002
FTFr07	rRNA	FTFr07	NC_008245.1	1377867	1379396	R	16S ribosomal RNA	complement(1377867..1379396)	Francisella tularensis subsp. tularensis FSC198	4199999
FTFr08	rRNA	FTFr08	NC_008245.1	1767843	1767959	R	5S ribosomal RNA	complement(1767843..1767959)	Francisella tularensis subsp. tularensis FSC198	4199744
FTFr09	rRNA	FTFr09	NC_008245.1	1768004	1770869	R	23S ribosomal RNA	complement(1768004..1770869)	Francisella tularensis subsp. tularensis FSC198	4200003
FTFr10	rRNA	FTFr10	NC_008245.1	1771202	1772731	R	16S ribosomal RNA	complement(1771202..1772731)	Francisella tularensis subsp. tularensis FSC198	4200000