-- dump date   	20140619_095116
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
393115000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
393115000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
393115000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115000004	Walker A motif; other site
393115000005	ATP binding site [chemical binding]; other site
393115000006	Walker B motif; other site
393115000007	arginine finger; other site
393115000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
393115000009	DnaA box-binding interface [nucleotide binding]; other site
393115000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
393115000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
393115000012	putative DNA binding surface [nucleotide binding]; other site
393115000013	dimer interface [polypeptide binding]; other site
393115000014	beta-clamp/clamp loader binding surface; other site
393115000015	beta-clamp/translesion DNA polymerase binding surface; other site
393115000016	Similar to Q881T0 Proline/betaine transporter from Pseudomonas syringae (438 aa). FASTA: opt: 271 Z-score: 314.7 E(): 1.2e-09 Smith-Waterman score: 271; 37.594 identity in 133 aa overlap. Truncation at N-terminal according to FASTA hits ORF ftt0003c
393115000017	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115000018	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115000019	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115000020	Similar to Q92TE2 Probable succinate-semialdehyde dehydrogenase from Rhizobium meliloti (484 aa). FASTA: opt: 622 Z-score: 785.3 E(): 6.9e-36 Smith-Waterman score: 622; 55.294 identity in 170 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element causing a truncation at N-terminal
393115000021	metabolite-proton symporter; Region: 2A0106; TIGR00883
393115000022	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
393115000023	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
393115000024	dimer interface [polypeptide binding]; other site
393115000025	anticodon binding site; other site
393115000026	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
393115000027	homodimer interface [polypeptide binding]; other site
393115000028	motif 1; other site
393115000029	active site
393115000030	motif 2; other site
393115000031	GAD domain; Region: GAD; pfam02938
393115000032	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
393115000033	active site
393115000034	motif 3; other site
393115000035	Similar to Q8A5U0 Glycosyltransferase from Bacteriodes thetaiotamicron (323 aa). FASTA: opt: 175 Z-score: 241.3 E(): 1.4e-05 Smith-Waterman score: 175; 38.144 identity in 97 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element causing a truncation at the C-terminal ORF ftt0008
393115000036	ISFtu1, fragment. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. Deletion of carboxy terminal region between aa 135 and 238 relative to full length ISFtu1
393115000037	Similar to MTH3_HAEAE (P20589) Modification methylase HaeIII from Haemophilus aegyptius (330 aa). FASTA: opt: 652 Z-score: 839.7 E(): 6.4e-39 Smith-Waterman score: 652; 57.310 identity in 171 aa overlap. This CDS is disrupted by the insertion of a fragment of an ISFtu1 element causing a truncation at N-terminal ORF ftt0010
393115000038	Similar to O68582 FnuDI restriction endonuclease from Fusobacterium nucleatum (284 aa). FASTA: .opt: 881 Z-score: 1029.1 E(): 1.8e-49 Smith-Waterman score: 881; 50.178 identity in 281 aa overlap . Contains an in-frame stop codon after aa 75 ORF ftt0011
393115000039	Similar to Q92C69 Hypothetical protein lin1322 from Listeria innocua (290 aa). FASTA: opt: 601 Z-score: 755.7 E(): 3e-34 Smith-Waterman score: 601; 31.507 identity in 292 aa. Contains a frameshift after aa 139. ORF ftt0012
393115000040	adenylosuccinate lyase; Provisional; Region: PRK07492
393115000041	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
393115000042	tetramer interface [polypeptide binding]; other site
393115000043	active site
393115000044	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
393115000045	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
393115000046	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
393115000047	HlyD family secretion protein; Region: HlyD_3; pfam13437
393115000048	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit [Translation, ribosomal structure and biogenesis]; Region: GatC; COG0721
393115000049	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
393115000050	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
393115000051	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
393115000052	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
393115000053	GatB domain; Region: GatB_Yqey; smart00845
393115000054	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
393115000055	oxyanion hole [active]
393115000056	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
393115000057	catalytic triad [active]
393115000058	Protein of unknown function (DUF3573); Region: DUF3573; pfam12097
393115000059	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000060	putative substrate translocation pore; other site
393115000061	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
393115000062	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme MccE; Region: PLPDE_III_MccE_like; cd06841
393115000063	dimer interface [polypeptide binding]; other site
393115000064	active site
393115000065	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
393115000066	catalytic residues [active]
393115000067	substrate binding site [chemical binding]; other site
393115000068	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115000069	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000070	IucA / IucC family; Region: IucA_IucC; pfam04183
393115000071	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
393115000072	ferric uptake regulator; Provisional; Region: fur; PRK09462
393115000073	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
393115000074	metal binding site 2 [ion binding]; metal-binding site
393115000075	putative DNA binding helix; other site
393115000076	metal binding site 1 [ion binding]; metal-binding site
393115000077	dimer interface [polypeptide binding]; other site
393115000078	structural Zn2+ binding site [ion binding]; other site
393115000079	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
393115000080	NADH dehydrogenase subunit B; Validated; Region: PRK06411
393115000081	NADH dehydrogenase subunit C; Provisional; Region: PRK06074
393115000082	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
393115000083	NADH dehydrogenase subunit D; Validated; Region: PRK06075
393115000084	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
393115000085	NADH dehydrogenase subunit E; Validated; Region: PRK07539
393115000086	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
393115000087	putative dimer interface [polypeptide binding]; other site
393115000088	[2Fe-2S] cluster binding site [ion binding]; other site
393115000089	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
393115000090	SLBB domain; Region: SLBB; pfam10531
393115000091	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
393115000092	NADH dehydrogenase subunit G; Validated; Region: PRK09129
393115000093	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
393115000094	catalytic loop [active]
393115000095	iron binding site [ion binding]; other site
393115000096	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
393115000097	MopB_NDH-1_NuoG2: The second domain of the NuoG subunit of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1), found in beta- and gammaproteobacteria. The NDH-1 is the first energy-transducting complex in the respiratory chain and functions as...; Region: MopB_NDH-1_NuoG2; cd02772
393115000098	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
393115000099	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
393115000100	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
393115000101	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
393115000102	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
393115000103	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L; Region: Oxidored_q2; cl00492
393115000104	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
393115000105	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
393115000106	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
393115000107	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
393115000108	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
393115000109	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
393115000110	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
393115000111	Membrane fusogenic activity; Region: BMFP; pfam04380
393115000112	Similar to CAD84104 (Q82XR1) Probable Mg(2+) chelatase family protein from Nitrosomonas europaea (500 aa). FASTA: opt: 1712 Z-score: 1729.4 E(): 1.8e-88 Smith-Waterman score: 1712; 54.582identity in 502 aa overlap. Contains two frameshifts after aa 44 and 442. Second frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt0046
393115000113	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
393115000114	substrate binding site [chemical binding]; other site
393115000115	active site
393115000116	ribosome maturation protein RimP; Reviewed; Region: PRK00092
393115000117	hypothetical protein; Provisional; Region: PRK14641
393115000118	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
393115000119	putative oligomer interface [polypeptide binding]; other site
393115000120	putative RNA binding site [nucleotide binding]; other site
393115000121	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
393115000122	NusA N-terminal domain; Region: NusA_N; pfam08529
393115000123	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
393115000124	RNA binding site [nucleotide binding]; other site
393115000125	homodimer interface [polypeptide binding]; other site
393115000126	NusA-like KH domain; Region: KH_5; pfam13184
393115000127	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
393115000128	G-X-X-G motif; other site
393115000129	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
393115000130	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
393115000131	translation initiation factor IF-2; Region: IF-2; TIGR00487
393115000132	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
393115000133	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
393115000134	G1 box; other site
393115000135	putative GEF interaction site [polypeptide binding]; other site
393115000136	GTP/Mg2+ binding site [chemical binding]; other site
393115000137	Switch I region; other site
393115000138	G2 box; other site
393115000139	G3 box; other site
393115000140	Switch II region; other site
393115000141	G4 box; other site
393115000142	G5 box; other site
393115000143	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
393115000144	Translation-initiation factor 2; Region: IF-2; pfam11987
393115000145	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
393115000146	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
393115000147	histidyl-tRNA synthetase; Region: hisS; TIGR00442
393115000148	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
393115000149	dimer interface [polypeptide binding]; other site
393115000150	motif 1; other site
393115000151	active site
393115000152	motif 2; other site
393115000153	motif 3; other site
393115000154	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
393115000155	anticodon binding site; other site
393115000156	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000157	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
393115000158	putative substrate translocation pore; other site
393115000159	Predicted ATPase [General function prediction only]; Region: COG1485
393115000160	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
393115000161	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
393115000162	RNA binding surface [nucleotide binding]; other site
393115000163	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
393115000164	active site
393115000165	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115000166	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000167	putative substrate translocation pore; other site
393115000168	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
393115000169	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
393115000170	F0F1 ATP synthase subunit C; Provisional; Region: PRK13464
393115000171	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
393115000172	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
393115000173	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
393115000174	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
393115000175	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
393115000176	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
393115000177	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
393115000178	beta subunit interaction interface [polypeptide binding]; other site
393115000179	Walker A motif; other site
393115000180	ATP binding site [chemical binding]; other site
393115000181	Walker B motif; other site
393115000182	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
393115000183	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
393115000184	core domain interface [polypeptide binding]; other site
393115000185	delta subunit interface [polypeptide binding]; other site
393115000186	epsilon subunit interface [polypeptide binding]; other site
393115000187	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
393115000188	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
393115000189	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
393115000190	alpha subunit interaction interface [polypeptide binding]; other site
393115000191	Walker A motif; other site
393115000192	ATP binding site [chemical binding]; other site
393115000193	Walker B motif; other site
393115000194	inhibitor binding site; inhibition site
393115000195	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
393115000196	F0F1 ATP synthase subunit epsilon; Provisional; Region: atpC; PRK13452
393115000197	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
393115000198	gamma subunit interface [polypeptide binding]; other site
393115000199	epsilon subunit interface [polypeptide binding]; other site
393115000200	LBP interface [polypeptide binding]; other site
393115000201	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
393115000202	GH18 domain of Chitinase D (ChiD).  ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins.  The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18; Region: GH18_chitinase_D-like; cd02871
393115000203	putative active site [active]
393115000204	Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704
393115000205	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
393115000206	putative GSH binding site [chemical binding]; other site
393115000207	catalytic residues [active]
393115000208	superoxide dismutase; Provisional; Region: PRK10543
393115000209	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
393115000210	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
393115000211	muropeptide transporter; Reviewed; Region: ampG; PRK11902
393115000212	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000213	putative substrate translocation pore; other site
393115000214	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
393115000215	dimer interface [polypeptide binding]; other site
393115000216	Citrate synthase; Region: Citrate_synt; pfam00285
393115000217	active site
393115000218	citrylCoA binding site [chemical binding]; other site
393115000219	NADH binding [chemical binding]; other site
393115000220	cationic pore residues; other site
393115000221	oxalacetate/citrate binding site [chemical binding]; other site
393115000222	coenzyme A binding site [chemical binding]; other site
393115000223	catalytic triad [active]
393115000224	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
393115000225	Iron-sulfur protein interface; other site
393115000226	proximal quinone binding site [chemical binding]; other site
393115000227	SdhD (CybS) interface [polypeptide binding]; other site
393115000228	proximal heme binding site [chemical binding]; other site
393115000229	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
393115000230	SdhC subunit interface [polypeptide binding]; other site
393115000231	proximal heme binding site [chemical binding]; other site
393115000232	cardiolipin binding site; other site
393115000233	Iron-sulfur protein interface; other site
393115000234	proximal quinone binding site [chemical binding]; other site
393115000235	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
393115000236	L-aspartate oxidase; Provisional; Region: PRK06175
393115000237	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
393115000238	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
393115000239	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
393115000240	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
393115000241	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
393115000242	TPP-binding site [chemical binding]; other site
393115000243	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
393115000244	dimer interface [polypeptide binding]; other site
393115000245	PYR/PP interface [polypeptide binding]; other site
393115000246	TPP binding site [chemical binding]; other site
393115000247	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
393115000248	E3 interaction surface; other site
393115000249	lipoyl attachment site [posttranslational modification]; other site
393115000250	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
393115000251	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
393115000252	E3 interaction surface; other site
393115000253	lipoyl attachment site [posttranslational modification]; other site
393115000254	e3 binding domain; Region: E3_binding; pfam02817
393115000255	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
393115000256	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
393115000257	nucleotide binding site [chemical binding]; other site
393115000258	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
393115000259	active site
393115000260	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14320
393115000261	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
393115000262	active site
393115000263	substrate binding site [chemical binding]; other site
393115000264	metal binding site [ion binding]; metal-binding site
393115000265	triosephosphate isomerase; Provisional; Region: PRK14567
393115000266	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
393115000267	substrate binding site [chemical binding]; other site
393115000268	dimer interface [polypeptide binding]; other site
393115000269	catalytic triad [active]
393115000270	Preprotein translocase SecG subunit; Region: SecG; pfam03840
393115000271	Similar to Q9CG05 LysR family transcriptional regulator from Lactococcus lactis (273 aa) .FASTA: opt: 186 Z-score: 225.0 E(): 0.00011 Smith-Waterman score: 186; 23.574 identity in 263 aa overlap. Contains an in-frame stop codon after aa 197 ORF ftt0082
393115000272	Peptidase propeptide and YPEB domain; Region: PepSY_2; pfam13670
393115000273	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
393115000274	HemN family oxidoreductase; Provisional; Region: PRK05660
393115000275	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
393115000276	FeS/SAM binding site; other site
393115000277	HemN C-terminal domain; Region: HemN_C; pfam06969
393115000278	Predicted membrane protein [Function unknown]; Region: COG2246
393115000279	GtrA-like protein; Region: GtrA; pfam04138
393115000280	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
393115000281	aconitate hydratase; Validated; Region: PRK09277
393115000282	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
393115000283	substrate binding site [chemical binding]; other site
393115000284	ligand binding site [chemical binding]; other site
393115000285	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
393115000286	substrate binding site [chemical binding]; other site
393115000287	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
393115000288	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
393115000289	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
393115000290	Walker A motif; other site
393115000291	Walker A/P-loop; other site
393115000292	ATP binding site [chemical binding]; other site
393115000293	ATP binding site [chemical binding]; other site
393115000294	Walker B motif; other site
393115000295	Similar to Q9HVD5 Hypothetical protein PA4657 from Pseudomonas aeruginosa (327 aa). FASTA: 552 Z-score: 636.7 E(): 1.3e-27 Smith-Waterman score: 552; 28.395 identity in 324 aa overlap. Contains 2 frameshifts after aa 73 and 158 ORF ftt0089c
393115000296	Protein of unknown function (DUF3429); Region: DUF3429; pfam11911
393115000297	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
393115000298	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
393115000299	Similar to Q92IY2 Cytochrome d ubiquinol oxidase subunit I from Rickettsia conorii (456 aa). FASTA: opt: 1445 Z-score: 1673.2 E(): 2.4e-85 Smith-Waterman score: 1443; 49.083identity in 436 aa overlap. Contains an in-frame stop codon after aa 80
393115000300	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
393115000301	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
393115000302	putative NAD(P) binding site [chemical binding]; other site
393115000303	putative active site [active]
393115000304	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
393115000305	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
393115000306	dimer interface [polypeptide binding]; other site
393115000307	phosphorylation site [posttranslational modification]
393115000308	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
393115000309	ATP binding site [chemical binding]; other site
393115000310	Mg2+ binding site [ion binding]; other site
393115000311	G-X-G motif; other site
393115000312	ATP-grasp domain; Region: ATP-grasp_4; cl17255
393115000313	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115000314	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115000315	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115000316	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
393115000317	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115000318	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
393115000319	Similar to Q9K0L1 IS1016C2 transposase from Neisseria meningitidis serogroup B strain MC58 (222 aa). FASTA: opt: 368 Z-score: 482.6 E(): 5e-19 Smith-Waterman score: 368; 49.123 identity in 114 aa overlap. This CDS has no start codon due to disruption by the insertion of an ISFtu1 element at the N-terminal end Identical to carboxy terminus of FTF1053c and FTF1792c ORF ftt0100
393115000320	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
393115000321	dimer interface [polypeptide binding]; other site
393115000322	catalytic triad [active]
393115000323	Similar to NP_927686.1| Transposase, IS982 family from Photorhabdus luminescens subsp laumondii TTO1. Score = 170 bits (431),Expect = 2e-41 Identities = 95/258 (36),Positives = 146/258 (56), Gaps = 5/258 (1). Contains an in-frame stop codon after aa 87 and frameshifts after aa 138 and 216 ORF ftt0102
393115000324	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000325	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
393115000326	multidrug efflux protein; Reviewed; Region: PRK09579
393115000327	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
393115000328	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
393115000329	HlyD family secretion protein; Region: HlyD_3; pfam13437
393115000330	Disulfide bond formation protein DsbB; Region: DsbB; pfam02600
393115000331	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13296
393115000332	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
393115000333	active site
393115000334	NTP binding site [chemical binding]; other site
393115000335	metal binding triad [ion binding]; metal-binding site
393115000336	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
393115000337	lipid A export permease/ATP-binding protein MsbA; Region: MsbA_lipidA; TIGR02203
393115000338	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
393115000339	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
393115000340	Walker A/P-loop; other site
393115000341	ATP binding site [chemical binding]; other site
393115000342	Q-loop/lid; other site
393115000343	ABC transporter signature motif; other site
393115000344	Walker B; other site
393115000345	D-loop; other site
393115000346	H-loop/switch region; other site
393115000347	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
393115000348	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
393115000349	DNA polymerase I; Provisional; Region: PRK05755
393115000350	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
393115000351	active site
393115000352	metal binding site 1 [ion binding]; metal-binding site
393115000353	putative 5' ssDNA interaction site; other site
393115000354	metal binding site 3; metal-binding site
393115000355	metal binding site 2 [ion binding]; metal-binding site
393115000356	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
393115000357	putative DNA binding site [nucleotide binding]; other site
393115000358	putative metal binding site [ion binding]; other site
393115000359	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
393115000360	active site
393115000361	catalytic site [active]
393115000362	substrate binding site [chemical binding]; other site
393115000363	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
393115000364	active site
393115000365	DNA binding site [nucleotide binding]
393115000366	catalytic site [active]
393115000367	pantothenate kinase; Reviewed; Region: PRK13324
393115000368	phosphopentomutase; Provisional; Region: PRK05362
393115000369	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
393115000370	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
393115000371	intersubunit interface [polypeptide binding]; other site
393115000372	active site
393115000373	catalytic residue [active]
393115000374	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
393115000375	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
393115000376	Nucleoside recognition; Region: Gate; pfam07670
393115000377	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
393115000378	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
393115000379	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
393115000380	Nucleoside recognition; Region: Gate; pfam07670
393115000381	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
393115000382	thymidylate kinase; Validated; Region: tmk; PRK00698
393115000383	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
393115000384	TMP-binding site; other site
393115000385	ATP-binding site [chemical binding]; other site
393115000386	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
393115000387	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
393115000388	G1 box; other site
393115000389	putative GEF interaction site [polypeptide binding]; other site
393115000390	GTP/Mg2+ binding site [chemical binding]; other site
393115000391	Switch I region; other site
393115000392	G2 box; other site
393115000393	G3 box; other site
393115000394	Switch II region; other site
393115000395	G4 box; other site
393115000396	G5 box; other site
393115000397	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
393115000398	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
393115000399	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
393115000400	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
393115000401	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
393115000402	GTP binding site [chemical binding]; other site
393115000403	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
393115000404	Part of AAA domain; Region: AAA_19; pfam13245
393115000405	Family description; Region: UvrD_C_2; pfam13538
393115000406	Similar to OPPA_HAEIN (P71370) Periplasmic oligopeptide-binding protein (precursor) from Haemophilus influenzae (541 aa). FASTA: opt: 924 Z-score: 1112.1 E(): 4.7e-54 Smith-Waterman score: 924; 34.490identity in 461 aa overlap oligopeptide transporter, subunit A, ABC transporter, periplasmic protein
393115000407	Similar to Q9CJT2 (Q9CJT2) OppB from Pasteurella multicoda (306 aa) FASTA: opt: 953 Z-score: 1065.0 E(): 2e-51 Smith-Waterman score: 953; 46.645 identity in 313 aa overlap. Contains a frameshift after aa 89
393115000408	Similar to Q87MY7 Oligopeptide ABC transporter,permease frim Vibrio parahaemolyticus (300 aa). FASTA: opt: 1042 Z-score: 1224.8 E(): 2.3e-60 Smith-Waterman score: 1042; 52.857 identity in 280 aa overlap. Contains no start codon and a frameshift after aa 74
393115000409	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
393115000410	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
393115000411	Walker A/P-loop; other site
393115000412	ATP binding site [chemical binding]; other site
393115000413	Q-loop/lid; other site
393115000414	ABC transporter signature motif; other site
393115000415	Walker B; other site
393115000416	D-loop; other site
393115000417	H-loop/switch region; other site
393115000418	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
393115000419	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
393115000420	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
393115000421	Walker A/P-loop; other site
393115000422	ATP binding site [chemical binding]; other site
393115000423	Q-loop/lid; other site
393115000424	ABC transporter signature motif; other site
393115000425	Walker B; other site
393115000426	D-loop; other site
393115000427	H-loop/switch region; other site
393115000428	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
393115000429	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000430	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115000431	putative substrate translocation pore; other site
393115000432	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000433	putative substrate translocation pore; other site
393115000434	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115000435	glycerol kinase; Provisional; Region: glpK; PRK00047
393115000436	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
393115000437	N- and C-terminal domain interface [polypeptide binding]; other site
393115000438	active site
393115000439	MgATP binding site [chemical binding]; other site
393115000440	catalytic site [active]
393115000441	metal binding site [ion binding]; metal-binding site
393115000442	glycerol binding site [chemical binding]; other site
393115000443	homotetramer interface [polypeptide binding]; other site
393115000444	homodimer interface [polypeptide binding]; other site
393115000445	FBP binding site [chemical binding]; other site
393115000446	protein IIAGlc interface [polypeptide binding]; other site
393115000447	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115000448	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115000449	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115000450	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
393115000451	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
393115000452	amphipathic channel; other site
393115000453	Asn-Pro-Ala signature motifs; other site
393115000454	Similar to YGGB_EDWIC (O52401) Hypothetical UPF0003 protein in iciA-fba intergenic region from Edwardsiella ictaluri (286 aa). FASTA: opt: 317 Z-score: 385.5 E(): 1.4e-13 Smith-Waterman score: 317; 33.121 identity in 157 aa overlap. Truncation of C-terminal according to FASTA hits ORF ftt0135
393115000455	AAA domain; Region: AAA_30; pfam13604
393115000456	Family description; Region: UvrD_C_2; pfam13538
393115000457	elongation factor Tu; Reviewed; Region: PRK00049
393115000458	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
393115000459	G1 box; other site
393115000460	GEF interaction site [polypeptide binding]; other site
393115000461	GTP/Mg2+ binding site [chemical binding]; other site
393115000462	Switch I region; other site
393115000463	G2 box; other site
393115000464	G3 box; other site
393115000465	Switch II region; other site
393115000466	G4 box; other site
393115000467	G5 box; other site
393115000468	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
393115000469	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
393115000470	Antibiotic Binding Site [chemical binding]; other site
393115000471	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
393115000472	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
393115000473	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
393115000474	putative homodimer interface [polypeptide binding]; other site
393115000475	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
393115000476	heterodimer interface [polypeptide binding]; other site
393115000477	homodimer interface [polypeptide binding]; other site
393115000478	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
393115000479	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
393115000480	23S rRNA interface [nucleotide binding]; other site
393115000481	L7/L12 interface [polypeptide binding]; other site
393115000482	putative thiostrepton binding site; other site
393115000483	L25 interface [polypeptide binding]; other site
393115000484	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
393115000485	mRNA/rRNA interface [nucleotide binding]; other site
393115000486	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
393115000487	23S rRNA interface [nucleotide binding]; other site
393115000488	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
393115000489	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
393115000490	core dimer interface [polypeptide binding]; other site
393115000491	peripheral dimer interface [polypeptide binding]; other site
393115000492	L10 interface [polypeptide binding]; other site
393115000493	L11 interface [polypeptide binding]; other site
393115000494	putative EF-Tu interaction site [polypeptide binding]; other site
393115000495	putative EF-G interaction site [polypeptide binding]; other site
393115000496	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
393115000497	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
393115000498	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
393115000499	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
393115000500	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
393115000501	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
393115000502	RPB3 interaction site [polypeptide binding]; other site
393115000503	RPB1 interaction site [polypeptide binding]; other site
393115000504	RPB11 interaction site [polypeptide binding]; other site
393115000505	RPB10 interaction site [polypeptide binding]; other site
393115000506	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
393115000507	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
393115000508	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
393115000509	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
393115000510	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
393115000511	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
393115000512	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
393115000513	cleft; other site
393115000514	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
393115000515	Rpb1 - Rpb5 interaction site [polypeptide binding]; other site
393115000516	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
393115000517	DNA binding site [nucleotide binding]
393115000518	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
393115000519	Protein of unknown function (DUF1049); Region: DUF1049; pfam06305
393115000520	UGMP family protein; Validated; Region: PRK09604
393115000521	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
393115000522	Fatty acid desaturase; Region: FA_desaturase; pfam00487
393115000523	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
393115000524	Di-iron ligands [ion binding]; other site
393115000525	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
393115000526	S-adenosylmethionine synthetase; Validated; Region: PRK05250
393115000527	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
393115000528	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
393115000529	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
393115000530	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
393115000531	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK14591
393115000532	RimM N-terminal domain; Region: RimM; pfam01782
393115000533	PRC-barrel domain; Region: PRC; pfam05239
393115000534	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
393115000535	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
393115000536	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
393115000537	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
393115000538	active site
393115000539	DNA binding site [nucleotide binding]
393115000540	Int/Topo IB signature motif; other site
393115000541	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
393115000542	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
393115000543	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
393115000544	HAD superfamily, subfamily IIIB (Acid phosphatase); Region: Acid_phosphat_B; cl17236
393115000545	Glucosyl transferase GtrII; Region: Glucos_trans_II; pfam14264
393115000546	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
393115000547	putative active site [active]
393115000548	Ap4A binding site [chemical binding]; other site
393115000549	nudix motif; other site
393115000550	putative metal binding site [ion binding]; other site
393115000551	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
393115000552	active site
393115000553	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
393115000554	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
393115000555	amidase catalytic site [active]
393115000556	Zn binding residues [ion binding]; other site
393115000557	substrate binding site [chemical binding]; other site
393115000558	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
393115000559	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
393115000560	Mg2+ binding site [ion binding]; other site
393115000561	G-X-G motif; other site
393115000562	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
393115000563	anchoring element; other site
393115000564	dimer interface [polypeptide binding]; other site
393115000565	ATP binding site [chemical binding]; other site
393115000566	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
393115000567	active site
393115000568	metal binding site [ion binding]; metal-binding site
393115000569	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
393115000570	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000571	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
393115000572	putative substrate translocation pore; other site
393115000573	outer membrane assembly lipoprotein YfgL; Region: assembly_YfgL; TIGR03300
393115000574	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
393115000575	Trp docking motif [polypeptide binding]; other site
393115000576	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
393115000577	TPR motif; other site
393115000578	binding surface
393115000579	Tetratricopeptide repeat; Region: TPR_16; pfam13432
393115000580	glutamyl-tRNA reductase; Provisional; Region: PRK13940
393115000581	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
393115000582	tRNA; other site
393115000583	putative tRNA binding site [nucleotide binding]; other site
393115000584	putative NADP binding site [chemical binding]; other site
393115000585	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
393115000586	peptide chain release factor 1; Validated; Region: prfA; PRK00591
393115000587	This domain is found in peptide chain release factors; Region: PCRF; smart00937
393115000588	RF-1 domain; Region: RF-1; pfam00472
393115000589	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
393115000590	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115000591	Similar to YCA8_PSEPK (Q88DL7) Hypothetical UPF0247 protein PP4808 from Pseudomonas putida (155 aa). FASTA: opt: 433 Z-score: 550.0 E(): 9.6e-23 Smith-Waterman score: 433; 42.254 identity in 142 aa overlap. This CDS lacks a start codon due to the insertion of an ISFtu1 element at the N-terminal ORF ftt0170c
393115000592	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115000593	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115000594	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115000595	ORF ftt0172
393115000596	Similar to Q87J48 Hypothetical protein from Vibro parahaemolyticus (305 aa). FASTA: opt: 1031 Z-score: 1265.1 E(): 1.3e-62 Smith-Waterman score: 1031; 52.365 identity in 296 aa overlap. Contains a frameshift after aa 227 and an in-frame stop aa at 267 ORF ftt0173
393115000597	YGGT family; Region: YGGT; pfam02325
393115000598	YGGT family; Region: YGGT; pfam02325
393115000599	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
393115000600	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
393115000601	Walker A/P-loop; other site
393115000602	ATP binding site [chemical binding]; other site
393115000603	Q-loop/lid; other site
393115000604	ABC transporter signature motif; other site
393115000605	Walker B; other site
393115000606	D-loop; other site
393115000607	H-loop/switch region; other site
393115000608	Similar to Q836Q4 ABC transporter, permease protein from Enterococcus faecalis (585 aa). FASTA: opt: 1474 Z-score: 1670.8 E(): 3.3e-85 Smith-Waterman score: 1476; 39.519identity in 582 aa overlap. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt0176c
393115000609	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
393115000610	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
393115000611	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
393115000612	Coenzyme A binding pocket [chemical binding]; other site
393115000613	RimK-like ATPgrasp N-terminal domain; Region: RLAN; pfam14401
393115000614	alpha-L-glutamate ligases, RimK family; Region: rimK_fam; TIGR00768
393115000615	ATP-grasp domain; Region: ATP-grasp_4; cl17255
393115000616	Similar to CAD86320 (Q82SD2) DNA internalization-related competence protein ComEC/Rec2 from Nitrosomonas europaea (799 aa). FASTA: opt: 531 Z-score: 549.2 E(): 9.6e-23 Smith-Waterman score: 554; 23.668 identity in 638 aa overlap. Contains a frameshift after aa 225 ORF ftt0179
393115000617	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
393115000618	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
393115000619	putative acyl-acceptor binding pocket; other site
393115000620	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
393115000621	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
393115000622	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
393115000623	RNA binding site [nucleotide binding]; other site
393115000624	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
393115000625	RNA binding site [nucleotide binding]; other site
393115000626	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
393115000627	RNA binding site [nucleotide binding]; other site
393115000628	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
393115000629	RNA binding site [nucleotide binding]; other site
393115000630	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
393115000631	RNA binding site [nucleotide binding]; other site
393115000632	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
393115000633	RNA binding site [nucleotide binding]; other site
393115000634	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
393115000635	nucleoside/Zn binding site; other site
393115000636	dimer interface [polypeptide binding]; other site
393115000637	catalytic motif [active]
393115000638	D-alanyl-alanine synthetase A; Provisional; Region: PRK14569
393115000639	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
393115000640	ATP-grasp domain; Region: ATP-grasp_4; cl17255
393115000641	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
393115000642	Cell division protein FtsQ; Region: FtsQ; pfam03799
393115000643	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
393115000644	Cell division protein FtsA; Region: FtsA; smart00842
393115000645	Cell division protein FtsA; Region: FtsA; pfam14450
393115000646	cell division protein FtsZ; Validated; Region: PRK09330
393115000647	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
393115000648	nucleotide binding site [chemical binding]; other site
393115000649	SulA interaction site; other site
393115000650	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
393115000651	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
393115000652	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14957
393115000653	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115000654	Walker A motif; other site
393115000655	ATP binding site [chemical binding]; other site
393115000656	Walker B motif; other site
393115000657	DNA polymerase III subunit delta'; Validated; Region: PRK08485
393115000658	arginine finger; other site
393115000659	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
393115000660	This domain is found in peptide chain release factors; Region: PCRF; smart00937
393115000661	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
393115000662	RF-1 domain; Region: RF-1; pfam00472
393115000663	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
393115000664	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
393115000665	dimer interface [polypeptide binding]; other site
393115000666	putative anticodon binding site; other site
393115000667	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
393115000668	motif 1; other site
393115000669	active site
393115000670	motif 2; other site
393115000671	motif 3; other site
393115000672	hypothetical protein; Provisional; Region: PRK05208
393115000673	CAAX protease self-immunity; Region: Abi; pfam02517
393115000674	Eps15 homology domain; Region: EH; smart00027
393115000675	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
393115000676	Glutaminase; Region: Glutaminase; cl00907
393115000677	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
393115000678	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
393115000679	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
393115000680	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
393115000681	glutamine synthetase; Region: PLN02284
393115000682	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
393115000683	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
393115000684	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
393115000685	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
393115000686	Similar to Q87MQ6 Putative HAAAP family transport protein from Vibrio parahaemolyticus (441 aa). FASTA: opt: 848 Z-score: 1002.0 E(): 5.8e-48 Smith-Waterman score: 848; 36.292 identity in 383 aa overlap. CDS is interrupted by an ISFtu2 element. It also contains a frameshift after aa 190 and an in-frame stop codon after aa 401 ORF ftt0201
393115000687	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
393115000688	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115000689	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
393115000690	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
393115000691	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
393115000692	purine monophosphate binding site [chemical binding]; other site
393115000693	dimer interface [polypeptide binding]; other site
393115000694	putative catalytic residues [active]
393115000695	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
393115000696	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
393115000697	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
393115000698	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
393115000699	GDP-binding site [chemical binding]; other site
393115000700	ACT binding site; other site
393115000701	IMP binding site; other site
393115000702	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
393115000703	active site
393115000704	Similar to AAO90632 (Q83CJ6) Dienelactone hydrolase family protein from Coxiella burnetti (237 aa). FASTA: opt: 718 Z-score: 895.1 E(): 5.2e-42 Smith-Waterman score: 718; 46.809 identity in 235 aa overlap. Contains a frameshift after aa 54. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt0206c
393115000705	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
393115000706	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
393115000707	dimer interface [polypeptide binding]; other site
393115000708	putative PBP binding regions; other site
393115000709	ABC-ATPase subunit  interface; other site
393115000710	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
393115000711	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
393115000712	Walker A/P-loop; other site
393115000713	ATP binding site [chemical binding]; other site
393115000714	Q-loop/lid; other site
393115000715	ABC transporter signature motif; other site
393115000716	Walker B; other site
393115000717	D-loop; other site
393115000718	H-loop/switch region; other site
393115000719	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
393115000720	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
393115000721	intersubunit interface [polypeptide binding]; other site
393115000722	Similar to AAO90981 (Q83BM0) Major facilitator family transporter from Coxiella burnetti (428 aa). FASTA: opt: 399 Z-score: 467.4 E(): 3.5e-18 Smith-Waterman score: 502; 25.307 identity in 407 aa overlap. Contains several stop codons ORF ftt0210c
393115000723	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
393115000724	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
393115000725	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
393115000726	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
393115000727	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
393115000728	primosome assembly protein PriA; Validated; Region: PRK05580
393115000729	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
393115000730	ATP binding site [chemical binding]; other site
393115000731	putative Mg++ binding site [ion binding]; other site
393115000732	helicase superfamily c-terminal domain; Region: HELICc; smart00490
393115000733	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115000734	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115000735	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115000736	hypothetical protein, pseudogene. This CDS lacks a start codon due to an interruption by an ISFtu1 element at the N-terminal end ORF ftt0217
393115000737	Similar to Q9I539 Cytochrome b561 from Pseudomonas aeruginosa (182 aa). FASTA: opt: 265 Z-score: 332.5 E(): 1.3e-10 Smith-Waterman score: 265; 30.357 identity in 168 aa overlap. Contains an in-frame stop codon after aa 50 ORF ftt0218c
393115000738	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
393115000739	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
393115000740	Phosphoesterase family; Region: Phosphoesterase; pfam04185
393115000741	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
393115000742	LamB/YcsF family protein; Provisional; Region: PRK05406
393115000743	Similar to Q8NW92 Hypothetical protein MW1559 from Staphylococcus aureus (244 aa). FASTA: opt: 350 Z-score: 439.8 E(): 1.2e-16 Smith-Waterman score: 350; 38.012 identity in 171 aa overlap. Contains an in-frame stop codon after aa 14 ORF ftt0224c
393115000744	Similar to AAO91543 (Q83A52) Major facilitator family transporter from Coxiella burnetti (443 aa). FASTA: opt: 546 Z-score: 623.3 E(): 7.3e-27 Smith-Waterman score: 546; 28.693 identity in 352 aa overlap. This CDS has no start codon caused by insertion of an ISFtu1 element at N-terminal ORF ftt0225c
393115000745	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115000746	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115000747	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115000748	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
393115000749	catalytic site [active]
393115000750	putative active site [active]
393115000751	putative substrate binding site [chemical binding]; other site
393115000752	dimer interface [polypeptide binding]; other site
393115000753	elongation factor P; Validated; Region: PRK00529
393115000754	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
393115000755	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
393115000756	RNA binding site [nucleotide binding]; other site
393115000757	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
393115000758	RNA binding site [nucleotide binding]; other site
393115000759	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
393115000760	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
393115000761	putative acyl-acceptor binding pocket; other site
393115000762	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
393115000763	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
393115000764	putative acyl-acceptor binding pocket; other site
393115000765	membrane protein insertase; Provisional; Region: PRK01318
393115000766	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
393115000767	hypothetical protein; Provisional; Region: PRK14375
393115000768	Ribonuclease P; Region: Ribonuclease_P; pfam00825
393115000769	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
393115000770	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
393115000771	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
393115000772	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
393115000773	shikimate binding site; other site
393115000774	NAD(P) binding site [chemical binding]; other site
393115000775	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
393115000776	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
393115000777	NAD(P) binding site [chemical binding]; other site
393115000778	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115000779	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
393115000780	Predicted methyltransferases [General function prediction only]; Region: COG0313
393115000781	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
393115000782	putative SAM binding site [chemical binding]; other site
393115000783	putative homodimer interface [polypeptide binding]; other site
393115000784	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
393115000785	Mitochondrial PGP phosphatase; Region: PGP_phosphatase; pfam09419
393115000786	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
393115000787	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
393115000788	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
393115000789	N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_b2; cd09204
393115000790	PLD-like domain; Region: PLDc_2; pfam13091
393115000791	putative homodimer interface [polypeptide binding]; other site
393115000792	putative active site [active]
393115000793	catalytic site [active]
393115000794	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
393115000795	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
393115000796	ATP binding site [chemical binding]; other site
393115000797	putative Mg++ binding site [ion binding]; other site
393115000798	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115000799	nucleotide binding region [chemical binding]; other site
393115000800	ATP-binding site [chemical binding]; other site
393115000801	Domain of unknown function (DUF3427); Region: DUF3427; pfam11907
393115000802	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
393115000803	Ligand Binding Site [chemical binding]; other site
393115000804	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
393115000805	Ligand Binding Site [chemical binding]; other site
393115000806	hypothetical protein, pseudogene; This CDS lacks a start codon due to an interruption by an ISFtu1 element at the N-terminal end ORF ftt0246c
393115000807	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115000808	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115000809	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115000810	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
393115000811	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
393115000812	G1 box; other site
393115000813	GTP/Mg2+ binding site [chemical binding]; other site
393115000814	Switch I region; other site
393115000815	G2 box; other site
393115000816	G3 box; other site
393115000817	Switch II region; other site
393115000818	G4 box; other site
393115000819	G5 box; other site
393115000820	Nucleoside recognition; Region: Gate; pfam07670
393115000821	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
393115000822	Nucleoside recognition; Region: Gate; pfam07670
393115000823	pyruvate phosphate dikinase; Provisional; Region: PRK09279
393115000824	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
393115000825	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
393115000826	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
393115000827	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
393115000828	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
393115000829	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
393115000830	homodimer interface [polypeptide binding]; other site
393115000831	substrate-cofactor binding pocket; other site
393115000832	catalytic residue [active]
393115000833	Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; Region: LeuA; COG0119
393115000834	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
393115000835	active site
393115000836	catalytic residues [active]
393115000837	metal binding site [ion binding]; metal-binding site
393115000838	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115000839	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115000840	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115000841	Putative lipopolysaccharide-modifying enzyme; Region: CAP10; smart00672
393115000842	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
393115000843	RNB domain; Region: RNB; pfam00773
393115000844	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
393115000845	putative hydrolase; Provisional; Region: PRK11460
393115000846	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
393115000847	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
393115000848	domain interfaces; other site
393115000849	active site
393115000850	camphor resistance protein CrcB; Provisional; Region: PRK14226
393115000851	Zinc-finger domain; Region: zf-CHCC; cl01821
393115000852	ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986
393115000853	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
393115000854	dimer interface [polypeptide binding]; other site
393115000855	conserved gate region; other site
393115000856	putative PBP binding loops; other site
393115000857	ABC-ATPase subunit interface; other site
393115000858	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
393115000859	dimer interface [polypeptide binding]; other site
393115000860	conserved gate region; other site
393115000861	putative PBP binding loops; other site
393115000862	ABC-ATPase subunit interface; other site
393115000863	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
393115000864	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
393115000865	Walker A/P-loop; other site
393115000866	ATP binding site [chemical binding]; other site
393115000867	Q-loop/lid; other site
393115000868	ABC transporter signature motif; other site
393115000869	Walker B; other site
393115000870	D-loop; other site
393115000871	H-loop/switch region; other site
393115000872	ABC nitrate/sulfonate/bicarbonate family transporter, ATPase subunit; Region: ABC_transp; pfam09821
393115000873	Protein of unknown function (DUF3573); Region: DUF3573; pfam12097
393115000874	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
393115000875	TrkA-N domain; Region: TrkA_N; pfam02254
393115000876	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
393115000877	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
393115000878	trimer interface [polypeptide binding]; other site
393115000879	putative metal binding site [ion binding]; other site
393115000880	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
393115000881	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
393115000882	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
393115000883	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
393115000884	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115000885	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115000886	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115000887	Similar to Q8CN60 Bicyclomycin resistance protein TcaB from Staphylococcus epidermidis (400 aa). FASTA: opt: 373 Z-score: 410.0 E(): 6.1e-15 Smith-Waterman score: 373; 29.412 identity in 238 aa overlap. Truncation at C-terminal according to FASTA hits ORF ftt0275c
393115000888	Similar to Q89LI3 Probable cyclohexadienyl dehydratase precusor from Bradyrhizobium japonicum (260 aa). FASTA: opt: 349 Z-score: 407.8 E(): 7.3e-15 Smith-Waterman score: 349; 30.841 identity in 214 aa overlap. Contains a frameshift after aa 73 ORF ftt0276c
393115000889	Membrane bound YbgT-like protein; Region: YbgT_YccB; pfam08173
393115000890	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
393115000891	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
393115000892	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
393115000893	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
393115000894	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115000895	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115000896	putative substrate translocation pore; other site
393115000897	cytochrome o ubiquinol oxidase subunit II; Region: CyoA; TIGR01433
393115000898	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
393115000899	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
393115000900	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
393115000901	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
393115000902	D-pathway; other site
393115000903	Putative ubiquinol binding site [chemical binding]; other site
393115000904	Low-spin heme (heme b) binding site [chemical binding]; other site
393115000905	Putative water exit pathway; other site
393115000906	Binuclear center (heme o3/CuB) [ion binding]; other site
393115000907	K-pathway; other site
393115000908	Putative proton exit pathway; other site
393115000909	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
393115000910	Subunit I/III interface [polypeptide binding]; other site
393115000911	Subunit III/IV interface [polypeptide binding]; other site
393115000912	cytochrome o ubiquinol oxidase subunit IV; Region: CyoD; TIGR02847
393115000913	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
393115000914	UbiA prenyltransferase family; Region: UbiA; pfam01040
393115000915	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
393115000916	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
393115000917	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
393115000918	trimer interface [polypeptide binding]; other site
393115000919	active site
393115000920	UDP-GlcNAc binding site [chemical binding]; other site
393115000921	lipid binding site [chemical binding]; lipid-binding site
393115000922	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1244
393115000923	pyridoxamine kinase; Validated; Region: PRK05756
393115000924	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
393115000925	dimer interface [polypeptide binding]; other site
393115000926	pyridoxal binding site [chemical binding]; other site
393115000927	ATP binding site [chemical binding]; other site
393115000928	Protein of unknown function (DUF3568); Region: DUF3568; pfam12092
393115000929	MoxR-like ATPases [General function prediction only]; Region: COG0714
393115000930	ATPase family associated with various cellular activities (AAA); Region: AAA_3; pfam07726
393115000931	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
393115000932	Protein of unknown function DUF58; Region: DUF58; pfam01882
393115000933	Domain of unknown function (DUF4381); Region: DUF4381; pfam14316
393115000934	VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_BatA_type; cd01467
393115000935	metal ion-dependent adhesion site (MIDAS); other site
393115000936	Similar to Q8ECP1 TPR domain protein from Shewanella oneidensis (679 aa). FASTA: opt: 1173 Z-score: 1061.1 E(): 3e-51 Smith-Waterman score: 1179; 32.305 identity in 616 aa overlap. Contains a frameshift after aa 332 This protein also has a match to Q93EJ8 Hypothetical 27.1 kDa protein from Francisella tularensis (231 aa). FASTA: opt: 1485 Z-score: 1347.0 E(): 3.5e-67 Smith-Waterman score: 1485; 96.943 identity in 229 aa overlap. This protein was originally incorrectly sequenced (Pubmed: 11526142) (direct communication with authors). C-terminal contains multiple 9bp tandem repeats ORF ftt0294
393115000937	Oxygen tolerance; Region: BatD; pfam13584
393115000938	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
393115000939	putative substrate binding pocket [chemical binding]; other site
393115000940	AC domain interface; other site
393115000941	catalytic triad [active]
393115000942	AB domain interface; other site
393115000943	interchain disulfide; other site
393115000944	DNA polymerase III chi subunit, HolC; Region: DNA_pol3_chi; cl01106
393115000945	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
393115000946	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
393115000947	HIGH motif; other site
393115000948	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
393115000949	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
393115000950	active site
393115000951	KMSKS motif; other site
393115000952	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
393115000953	tRNA binding surface [nucleotide binding]; other site
393115000954	anticodon binding site; other site
393115000955	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
393115000956	1-deoxy-D-xylulose-5-phosphate synthase; Region: PLN02225
393115000957	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
393115000958	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
393115000959	phosphate binding site [ion binding]; other site
393115000960	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
393115000961	dimer interface [polypeptide binding]; other site
393115000962	FMN binding site [chemical binding]; other site
393115000963	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_31; cd04690
393115000964	nudix motif; other site
393115000965	fumarate hydratase; Reviewed; Region: fumC; PRK00485
393115000966	Class II fumarases; Region: Fumarase_classII; cd01362
393115000967	active site
393115000968	tetramer interface [polypeptide binding]; other site
393115000969	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
393115000970	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
393115000971	HIGH motif; other site
393115000972	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
393115000973	active site
393115000974	KMSKS motif; other site
393115000975	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
393115000976	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115000977	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
393115000978	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
393115000979	Uncharacterized protein conserved in bacteria containing a pentein-type domain [Function unknown]; Region: COG4874
393115000980	Amidinotransferase; Region: Amidinotransf; pfam02274
393115000981	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
393115000982	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
393115000983	folate binding site [chemical binding]; other site
393115000984	NADP+ binding site [chemical binding]; other site
393115000985	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
393115000986	rRNA interaction site [nucleotide binding]; other site
393115000987	S8 interaction site; other site
393115000988	putative laminin-1 binding site; other site
393115000989	elongation factor Ts; Provisional; Region: tsf; PRK09377
393115000990	UBA/TS-N domain; Region: UBA; pfam00627
393115000991	Elongation factor TS; Region: EF_TS; pfam00889
393115000992	Elongation factor TS; Region: EF_TS; pfam00889
393115000993	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
393115000994	putative nucleotide binding site [chemical binding]; other site
393115000995	uridine monophosphate binding site [chemical binding]; other site
393115000996	homohexameric interface [polypeptide binding]; other site
393115000997	ribosome recycling factor; Reviewed; Region: frr; PRK00083
393115000998	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
393115000999	hinge region; other site
393115001000	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14836
393115001001	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
393115001002	catalytic residue [active]
393115001003	putative FPP diphosphate  binding site; other site
393115001004	putative FPP binding hydrophobic cleft; other site
393115001005	dimer interface [polypeptide binding]; other site
393115001006	putative IPP diphosphate binding site; other site
393115001007	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
393115001008	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
393115001009	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
393115001010	trimer interface [polypeptide binding]; other site
393115001011	active site
393115001012	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
393115001013	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
393115001014	S17 interaction site [polypeptide binding]; other site
393115001015	S8 interaction site; other site
393115001016	16S rRNA interaction site [nucleotide binding]; other site
393115001017	streptomycin interaction site [chemical binding]; other site
393115001018	23S rRNA interaction site [nucleotide binding]; other site
393115001019	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
393115001020	30S ribosomal protein S7; Validated; Region: PRK05302
393115001021	elongation factor G; Reviewed; Region: PRK00007
393115001022	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
393115001023	G1 box; other site
393115001024	putative GEF interaction site [polypeptide binding]; other site
393115001025	GTP/Mg2+ binding site [chemical binding]; other site
393115001026	Switch I region; other site
393115001027	G2 box; other site
393115001028	G3 box; other site
393115001029	Switch II region; other site
393115001030	G4 box; other site
393115001031	G5 box; other site
393115001032	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
393115001033	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
393115001034	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
393115001035	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
393115001036	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
393115001037	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
393115001038	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
393115001039	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
393115001040	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
393115001041	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
393115001042	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
393115001043	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
393115001044	putative translocon binding site; other site
393115001045	protein-rRNA interface [nucleotide binding]; other site
393115001046	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
393115001047	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
393115001048	G-X-X-G motif; other site
393115001049	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
393115001050	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
393115001051	23S rRNA interface [nucleotide binding]; other site
393115001052	5S rRNA interface [nucleotide binding]; other site
393115001053	putative antibiotic binding site [chemical binding]; other site
393115001054	L25 interface [polypeptide binding]; other site
393115001055	L27 interface [polypeptide binding]; other site
393115001056	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
393115001057	23S rRNA interface [nucleotide binding]; other site
393115001058	putative translocon interaction site; other site
393115001059	signal recognition particle (SRP54) interaction site; other site
393115001060	L23 interface [polypeptide binding]; other site
393115001061	trigger factor interaction site; other site
393115001062	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
393115001063	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
393115001064	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
393115001065	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
393115001066	RNA binding site [nucleotide binding]; other site
393115001067	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
393115001068	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
393115001069	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
393115001070	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
393115001071	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
393115001072	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
393115001073	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
393115001074	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
393115001075	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
393115001076	23S rRNA interface [nucleotide binding]; other site
393115001077	L21e interface [polypeptide binding]; other site
393115001078	5S rRNA interface [nucleotide binding]; other site
393115001079	L27 interface [polypeptide binding]; other site
393115001080	L5 interface [polypeptide binding]; other site
393115001081	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
393115001082	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
393115001083	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
393115001084	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
393115001085	23S rRNA binding site [nucleotide binding]; other site
393115001086	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
393115001087	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
393115001088	SecY translocase; Region: SecY; pfam00344
393115001089	Ribosomal protein L36; Region: Ribosomal_L36; cl00380
393115001090	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
393115001091	30S ribosomal protein S13; Region: bact_S13; TIGR03631
393115001092	30S ribosomal protein S11; Validated; Region: PRK05309
393115001093	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
393115001094	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
393115001095	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
393115001096	RNA binding surface [nucleotide binding]; other site
393115001097	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
393115001098	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
393115001099	alphaNTD homodimer interface [polypeptide binding]; other site
393115001100	alphaNTD - beta interaction site [polypeptide binding]; other site
393115001101	alphaNTD - beta' interaction site [polypeptide binding]; other site
393115001102	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
393115001103	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
393115001104	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115001105	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115001106	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115001107	ISFtu2, fragment. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa) over 156 aa. Only the carboxy terminal is present and that is disrupted by the insertion of ISFtu1 element resulting in 7 carboxyl aa missing.
393115001108	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
393115001109	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115001110	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115001111	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115001112	heat shock protein 90; Provisional; Region: PRK05218
393115001113	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
393115001114	ATP binding site [chemical binding]; other site
393115001115	Mg2+ binding site [ion binding]; other site
393115001116	G-X-G motif; other site
393115001117	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115001118	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115001119	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115001120	Similar to Q9I5X7 Hypothetical protein PA0559 from Pseudomonas aeruginosa (392 aa). FASTA: opt: 1403 Z-score: 1598.9 E(): 3.3e-81 Smith-Waterman score: 1403; 54.090identity in 379 aa overlap. This CDS contains no start codon due to an insertion of an ISFtu1 element as well as a frameshift and two in-frame stop codons. ORF ftt0358
393115001121	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
393115001122	short chain dehydrogenase; Provisional; Region: PRK05993
393115001123	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
393115001124	NADP binding site [chemical binding]; other site
393115001125	active site
393115001126	steroid binding site; other site
393115001127	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
393115001128	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115001129	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115001130	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115001131	SnoaL-like domain; Region: SnoaL_2; pfam12680
393115001132	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
393115001133	ferredoxin-NADP reductase; Provisional; Region: PRK10926
393115001134	FAD binding pocket [chemical binding]; other site
393115001135	FAD binding motif [chemical binding]; other site
393115001136	phosphate binding motif [ion binding]; other site
393115001137	beta-alpha-beta structure motif; other site
393115001138	NAD binding pocket [chemical binding]; other site
393115001139	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
393115001140	Glutamate-cysteine ligase; Region: Glu_cys_ligase; cl17352
393115001141	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
393115001142	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
393115001143	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
393115001144	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
393115001145	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
393115001146	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
393115001147	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
393115001148	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
393115001149	active site
393115001150	multimer interface [polypeptide binding]; other site
393115001151	CTP synthetase; Validated; Region: pyrG; PRK05380
393115001152	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
393115001153	Catalytic site [active]
393115001154	active site
393115001155	UTP binding site [chemical binding]; other site
393115001156	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
393115001157	active site
393115001158	putative oxyanion hole; other site
393115001159	catalytic triad [active]
393115001160	Similar to YFCC_ECOLI (P39263) Hypothetical protein yfcC from E. coli (506 aa). FASTA: opt: 1158 Z-score: 1316.5 E(): 1.8e-65 Smith-Waterman score: 1398; 42.656 identity in 497 aa overlap. Contains an in-frame stop aa after codon 283 and an internal in-frame deletion according to FASTA hits ORF ftt0375
393115001161	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115001162	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115001163	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115001164	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
393115001165	ISFtu2, fragment. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa) in 157 aa overlap.
393115001166	glutamate dehydrogenase; Provisional; Region: PRK09414
393115001167	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
393115001168	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
393115001169	NAD(P) binding site [chemical binding]; other site
393115001170	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
393115001171	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115001172	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
393115001173	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
393115001174	bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase; Provisional; Region: PRK05379
393115001175	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional proteins, also containing a Nudix hydrolase domain; Region: NMNAT_Nudix; cd02168
393115001176	active site
393115001177	(T/H)XGH motif; other site
393115001178	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
393115001179	nudix motif; other site
393115001180	N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) [Cell envelope biogenesis, outer membrane]; Region: GlmU; COG1207
393115001181	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
393115001182	Substrate binding site; other site
393115001183	Mg++ binding site; other site
393115001184	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
393115001185	active site
393115001186	substrate binding site [chemical binding]; other site
393115001187	CoA binding site [chemical binding]; other site
393115001188	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
393115001189	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
393115001190	glutaminase active site [active]
393115001191	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
393115001192	dimer interface [polypeptide binding]; other site
393115001193	active site
393115001194	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
393115001195	dimer interface [polypeptide binding]; other site
393115001196	active site
393115001197	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
393115001198	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
393115001199	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
393115001200	DNA-binding site [nucleotide binding]; DNA binding site
393115001201	RNA-binding motif; other site
393115001202	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
393115001203	metal binding site [ion binding]; metal-binding site
393115001204	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
393115001205	active site
393115001206	Putative catalytic domain of uncharacterized hypothetical proteins with one or two copies of the HKD motif; Region: PLDc_unchar6; cd09176
393115001207	PLD-like domain; Region: PLDc_2; pfam13091
393115001208	putative homodimer interface [polypeptide binding]; other site
393115001209	putative active site [active]
393115001210	catalytic site [active]
393115001211	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
393115001212	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
393115001213	CAP-like domain; other site
393115001214	active site
393115001215	primary dimer interface [polypeptide binding]; other site
393115001216	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
393115001217	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
393115001218	BNR repeat-like domain; Region: BNR_2; pfam13088
393115001219	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
393115001220	Asp-box motif; other site
393115001221	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
393115001222	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
393115001223	N-acetyl-D-glucosamine binding site [chemical binding]; other site
393115001224	catalytic residue [active]
393115001225	Predicted membrane protein [Function unknown]; Region: COG4325
393115001226	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
393115001227	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
393115001228	putative active site [active]
393115001229	putative PHP Thumb interface [polypeptide binding]; other site
393115001230	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
393115001231	generic binding surface II; other site
393115001232	generic binding surface I; other site
393115001233	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
393115001234	active site
393115001235	catalytic residues [active]
393115001236	metal binding site [ion binding]; metal-binding site
393115001237	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
393115001238	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
393115001239	FtsX-like permease family; Region: FtsX; pfam02687
393115001240	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
393115001241	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
393115001242	Walker A/P-loop; other site
393115001243	ATP binding site [chemical binding]; other site
393115001244	Q-loop/lid; other site
393115001245	ABC transporter signature motif; other site
393115001246	Walker B; other site
393115001247	D-loop; other site
393115001248	H-loop/switch region; other site
393115001249	lysine decarboxylase LdcC; Provisional; Region: PRK15399
393115001250	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
393115001251	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
393115001252	homodimer interface [polypeptide binding]; other site
393115001253	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115001254	catalytic residue [active]
393115001255	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
393115001256	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
393115001257	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
393115001258	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
393115001259	lipoyl attachment site [posttranslational modification]; other site
393115001260	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
393115001261	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
393115001262	tetramer interface [polypeptide binding]; other site
393115001263	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115001264	catalytic residue [active]
393115001265	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
393115001266	tetramer interface [polypeptide binding]; other site
393115001267	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115001268	catalytic residue [active]
393115001269	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
393115001270	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
393115001271	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
393115001272	shikimate binding site; other site
393115001273	NAD(P) binding site [chemical binding]; other site
393115001274	pullulanase, type I; Region: pulA_typeI; TIGR02104
393115001275	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
393115001276	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
393115001277	Ca binding site [ion binding]; other site
393115001278	active site
393115001279	catalytic site [active]
393115001280	glycogen branching enzyme; Provisional; Region: PRK12313
393115001281	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
393115001282	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
393115001283	active site
393115001284	catalytic site [active]
393115001285	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
393115001286	phosphoglucomutase; Region: PLN02307
393115001287	Phosphoglucomutase 1 (PGM1) catalyzes the bidirectional interconversion of glucose-1-phosphate (G-1-P) and glucose-6-phosphate (G-6-P) via a glucose 1,6-diphosphate intermediate, an important metabolic step in prokaryotes and eukaryotes. In one direction; Region: PGM1; cd03085
393115001288	substrate binding site [chemical binding]; other site
393115001289	dimer interface [polypeptide binding]; other site
393115001290	active site
393115001291	metal binding site [ion binding]; metal-binding site
393115001292	Similar to GLGC_ECOLI (P00584) Glucose-1-phosphate adenylyltransferase from E coli (430 aa). FASTA: opt: 1820 Z-score: 2287.0 E(): 1.7e-119 Smith-Waterman score: 1820; 59.198identity in 424 aa overlap
393115001293	glycogen synthase; Provisional; Region: glgA; PRK00654
393115001294	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
393115001295	ADP-binding pocket [chemical binding]; other site
393115001296	homodimer interface [polypeptide binding]; other site
393115001297	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
393115001298	homodimer interface [polypeptide binding]; other site
393115001299	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
393115001300	active site pocket [active]
393115001301	4-alpha-glucanotransferase; Provisional; Region: PRK14508
393115001302	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
393115001303	dimer interface [polypeptide binding]; other site
393115001304	motif 1; other site
393115001305	active site
393115001306	motif 2; other site
393115001307	motif 3; other site
393115001308	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
393115001309	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
393115001310	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115001311	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
393115001312	Similar to Q8ZRH1 Putative outer membrane lipoprotein from Salmonella typhimurium (119 aa). FASTA: opt: 327 Z-score: 429.7 bits: 84.9 E(): 4.4e-16 Smith-Waterman score: 327; 43.860 identity in 114 aa overlap ORF ftt0421
393115001313	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
393115001314	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143
393115001315	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115001316	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
393115001317	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
393115001318	Similar to Q8A541 Aspartokinase/homoserine dehydrogenase from Bacteriodes thetaiotamicron (811 aa). FASTA: opt: 1065 Z-score: 1231.9 E(): 1e-60 Smith-Waterman score: 1346; 32.025 identity in 815 aa overlap
393115001319	Similar to Q8PLH7 Homoserine kinase from Xanthomonas axonopodis (306 aa). FASTA: opt: 458 Z-score: 540.1 E(): 3.1e-22 Smith-Waterman score: 563; 36.246 identity in 309 aa overlap
393115001320	threonine synthase; Validated; Region: PRK09225
393115001321	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
393115001322	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115001323	catalytic residue [active]
393115001324	Similar to Q8FA02 Beta-galactosidase I from Leptospira interrogans (658 aa). FASTA: opt: 260 Z-score: 363.2 E(): 2.4e-12 Smith-Waterman score: 260; 50.000 39dentity in 76 aa overlap
393115001325	S-adenosylmethionine decarboxylase proenzyme, Bacillus form; Region: SAM_DCase_Bsu; TIGR03330
393115001326	spermidine synthase; Provisional; Region: PRK00811
393115001327	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115001328	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
393115001329	dimer interface [polypeptide binding]; other site
393115001330	active site
393115001331	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
393115001332	catalytic residues [active]
393115001333	substrate binding site [chemical binding]; other site
393115001334	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
393115001335	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
393115001336	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
393115001337	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
393115001338	putative active site; other site
393115001339	catalytic triad [active]
393115001340	putative dimer interface [polypeptide binding]; other site
393115001341	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
393115001342	putative active site [active]
393115001343	putative metal binding site [ion binding]; other site
393115001344	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
393115001345	active site
393115001346	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
393115001347	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
393115001348	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115001349	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
393115001350	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
393115001351	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
393115001352	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115001353	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115001354	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115001355	Similar to Q8M6V4 NADH dehydrogenase subunit 5 (Fragment) from Prioneris autothisbe (291 aa). FASTA: opt: 168 Z-score: 205.5 E(): 0.0013 Smith-Waterman score: 172; 28.241identity in 216 aa overlap. Contains a frameshift after aa 123 and a possible deletion on C-terminal ORF ftt0441c
393115001356	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115001357	putative substrate translocation pore; other site
393115001358	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
393115001359	Predicted membrane protein [Function unknown]; Region: COG4129
393115001360	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
393115001361	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115001362	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115001363	putative substrate translocation pore; other site
393115001364	Similar to Q9HZI7 Probable ATP-binding component of ABC transporter from Pseudomonas aeruginosa (640 aa). FASTA: opt: 1264 Z-score: 1173.6 E(): 1.8e-57 Smith-Waterman score: 1355; 38.629 identity in 642 aa overlap. Contains an in-frame stop codon after aa 389 and a frameshift after aa 584. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift
393115001365	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115001366	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
393115001367	putative substrate translocation pore; other site
393115001368	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
393115001369	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
393115001370	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
393115001371	active site
393115001372	HIGH motif; other site
393115001373	nucleotide binding site [chemical binding]; other site
393115001374	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
393115001375	KMSKS motif; other site
393115001376	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
393115001377	phosphoenolpyruvate carboxykinase; Provisional; Region: PRK09344
393115001378	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
393115001379	active site
393115001380	metal-binding site [ion binding]
393115001381	nucleotide-binding site [chemical binding]; other site
393115001382	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
393115001383	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
393115001384	Mg++ binding site [ion binding]; other site
393115001385	putative catalytic motif [active]
393115001386	putative substrate binding site [chemical binding]; other site
393115001387	UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane]; Region: MurD; COG0771
393115001388	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115001389	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
393115001390	cell division protein FtsW; Region: ftsW; TIGR02614
393115001391	uncharacterized YdjC-like family proteins from bacteria; Region: YdjC_like_3; cd10807
393115001392	putative active site [active]
393115001393	YdjC motif; other site
393115001394	Mg binding site [ion binding]; other site
393115001395	putative homodimer interface [polypeptide binding]; other site
393115001396	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
393115001397	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
393115001398	Ligand binding site; other site
393115001399	Putative Catalytic site; other site
393115001400	DXD motif; other site
393115001401	Endoplasmic reticulum-based factor for assembly of V-ATPase; Region: Vma12; pfam11712
393115001402	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
393115001403	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
393115001404	oxidative damage protection protein; Provisional; Region: PRK05408
393115001405	DsrC like protein; Region: DsrC; pfam04358
393115001406	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
393115001407	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
393115001408	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
393115001409	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
393115001410	dimer interface [polypeptide binding]; other site
393115001411	N-terminal domain interface [polypeptide binding]; other site
393115001412	putative inner membrane peptidase; Provisional; Region: PRK11778
393115001413	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
393115001414	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
393115001415	tandem repeat interface [polypeptide binding]; other site
393115001416	oligomer interface [polypeptide binding]; other site
393115001417	active site residues [active]
393115001418	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
393115001419	DNA polymerase III subunit delta'; Validated; Region: PRK07993
393115001420	DNA polymerase III subunit delta'; Validated; Region: PRK08485
393115001421	CRS1 / YhbY (CRM) domain; Region: CRS1_YhbY; pfam01985
393115001422	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
393115001423	dimer interface [polypeptide binding]; other site
393115001424	active site
393115001425	Schiff base residues; other site
393115001426	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
393115001427	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
393115001428	active site
393115001429	homotetramer interface [polypeptide binding]; other site
393115001430	homodimer interface [polypeptide binding]; other site
393115001431	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
393115001432	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
393115001433	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
393115001434	active site
393115001435	HIGH motif; other site
393115001436	nucleotide binding site [chemical binding]; other site
393115001437	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
393115001438	KMSK motif region; other site
393115001439	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
393115001440	tRNA binding surface [nucleotide binding]; other site
393115001441	anticodon binding site; other site
393115001442	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
393115001443	Organic solvent tolerance protein; Region: OstA_C; pfam04453
393115001444	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
393115001445	SurA N-terminal domain; Region: SurA_N; pfam09312
393115001446	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
393115001447	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
393115001448	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
393115001449	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
393115001450	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
393115001451	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
393115001452	active site
393115001453	metal binding site [ion binding]; metal-binding site
393115001454	Dehydroquinase class II; Region: DHquinase_II; pfam01220
393115001455	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
393115001456	trimer interface [polypeptide binding]; other site
393115001457	active site
393115001458	dimer interface [polypeptide binding]; other site
393115001459	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
393115001460	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
393115001461	carboxyltransferase (CT) interaction site; other site
393115001462	biotinylation site [posttranslational modification]; other site
393115001463	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
393115001464	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
393115001465	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
393115001466	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
393115001467	Helix-turn-helix domain; Region: HTH_25; pfam13413
393115001468	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
393115001469	Mechanosensitive ion channel; Region: MS_channel; pfam00924
393115001470	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
393115001471	EF-P lysine aminoacylase GenX; Region: genX; TIGR00462
393115001472	motif 1; other site
393115001473	dimer interface [polypeptide binding]; other site
393115001474	active site
393115001475	motif 2; other site
393115001476	motif 3; other site
393115001477	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
393115001478	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
393115001479	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
393115001480	DHH family; Region: DHH; pfam01368
393115001481	DHHA1 domain; Region: DHHA1; pfam02272
393115001482	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
393115001483	Domain of unknown function DUF20; Region: UPF0118; pfam01594
393115001484	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
393115001485	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
393115001486	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
393115001487	Protein of unknown function (DUF3281); Region: DUF3281; pfam11685
393115001488	Predicted GTPases [General function prediction only]; Region: COG1162
393115001489	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
393115001490	RNA binding site [nucleotide binding]; other site
393115001491	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
393115001492	GTPase/Zn-binding domain interface [polypeptide binding]; other site
393115001493	GTP/Mg2+ binding site [chemical binding]; other site
393115001494	G4 box; other site
393115001495	G5 box; other site
393115001496	G1 box; other site
393115001497	Switch I region; other site
393115001498	G2 box; other site
393115001499	G3 box; other site
393115001500	Switch II region; other site
393115001501	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; cl01951
393115001502	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
393115001503	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
393115001504	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
393115001505	ATP binding site [chemical binding]; other site
393115001506	Mg2+ binding site [ion binding]; other site
393115001507	G-X-G motif; other site
393115001508	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
393115001509	ATP binding site [chemical binding]; other site
393115001510	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
393115001511	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115001512	putative substrate translocation pore; other site
393115001513	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115001514	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115001515	putative substrate translocation pore; other site
393115001516	thioredoxin reductase; Provisional; Region: PRK10262
393115001517	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
393115001518	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
393115001519	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
393115001520	PLD-like domain; Region: PLDc_2; pfam13091
393115001521	putative active site [active]
393115001522	catalytic site [active]
393115001523	Putative catalytic domain, repeat 2, of vertebrate phospholipases, PLD3, PLD4 and PLD5, viral envelope proteins K4 and p37, and similar proteins; Region: PLDc_vPLD3_4_5_like_2; cd09107
393115001524	PLD-like domain; Region: PLDc_2; pfam13091
393115001525	putative active site [active]
393115001526	putative catalytic site [active]
393115001527	phosphoglycolate phosphatase; Provisional; Region: PRK13222
393115001528	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
393115001529	motif II; other site
393115001530	Transcriptional regulator [Transcription]; Region: LysR; COG0583
393115001531	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
393115001532	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
393115001533	putative effector binding pocket; other site
393115001534	dimerization interface [polypeptide binding]; other site
393115001535	Similar to Q8A342 Putative transmembrane efflux protein from Bacteroides thetaiotaomicron (380 aa). FASTA: opt: 990 Z-score: 985.6 E(): 5.3e-47 Smith-Waterman score: 990; 42.487 identity in 386 aa overlap. Contains a frameshift after aa 213 ORF ftt0493
393115001536	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
393115001537	Domain of Unknown Function (DUF1543); Region: DUF1543; pfam07566
393115001538	Domain of Unknown Function (DUF1543); Region: DUF1543; pfam07566
393115001539	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
393115001540	Similar to ASGX_PYRAB (Q9V262) Putative L-asparaginase from Pyrococcus abyssi (305 aa). FASTA: opt: 407 Z-score: 472.8 E(): 1.8e-18 Smith-Waterman score: 431; 34.483 identity in 290 aa overlap. Contains a frameshift after aa 37 ORF ftt0497c
393115001541	Similar to AAO80296 (Q838K6)Di-/tripeptide transporter from Enterococcus faecalis (493 aa). FASTA: opt: 907 Z-score: 1018.4 E(): 7.1e-49 Smith-Waterman score: 907; 34.623 identity in 491 aa overlap. Contains 2 in-frame stop codons after aa 379 and 420 ORF ftt0498c
393115001542	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
393115001543	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
393115001544	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
393115001545	CoA binding domain; Region: CoA_binding; smart00881
393115001546	CoA-ligase; Region: Ligase_CoA; pfam00549
393115001547	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
393115001548	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
393115001549	CoA-ligase; Region: Ligase_CoA; pfam00549
393115001550	TIGR03546 family protein; Region: TIGR03546
393115001551	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
393115001552	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
393115001553	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
393115001554	FMN binding site [chemical binding]; other site
393115001555	active site
393115001556	catalytic residues [active]
393115001557	substrate binding site [chemical binding]; other site
393115001558	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cl15777
393115001559	putative active site pocket [active]
393115001560	dimerization interface [polypeptide binding]; other site
393115001561	putative catalytic residue [active]
393115001562	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
393115001563	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
393115001564	ATP binding site [chemical binding]; other site
393115001565	Mg2+ binding site [ion binding]; other site
393115001566	G-X-G motif; other site
393115001567	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
393115001568	anchoring element; other site
393115001569	dimer interface [polypeptide binding]; other site
393115001570	ATP binding site [chemical binding]; other site
393115001571	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
393115001572	active site
393115001573	putative metal-binding site [ion binding]; other site
393115001574	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
393115001575	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
393115001576	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
393115001577	active site
393115001578	multimer interface [polypeptide binding]; other site
393115001579	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
393115001580	predicted active site [active]
393115001581	catalytic triad [active]
393115001582	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115001583	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115001584	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115001585	Similar to Q9KKW6 L-lactate dehydrogenase from Vibrio cholerae (378 aa). FASTA: opt: 927 Z-score: 1134.7 E(): 2.6e-55 Smith-Waterman score: 999; 43.005 identity in 386 aa overlap. Contains a frameshift after aa 179
393115001586	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
393115001587	Similar to Q8D5V2 Fe-S oxidoreductase from Vibrio vulnificus (946 aa). FASTA: opt: 1932 Z-score: 2064.4 E(): 3.9e-107 Smith-Waterman score: 2293; 36.670 identity in 1039 aa overlap. Contains a ~40 aa insertion,a frameshift at a heptanucleotide sequence after aa 307 and so could be part of a programmed translational frameshift, an in-frame stop codon after aa 326 and a 2nd frame shift after aa 600 ORF ftt0516
393115001588	Similar to Q8YNJ9 NADH-dependent butanol dehydrogenase from Anabaena sp. (384 aa). FASTA: opt: 1347 Z-score: 1668.9 E(): 4.6e-85 Smith-Waterman score: 1347; 52.468 identity in 385 aa overlap. contains a frameshift after aa 175. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt0517
393115001589	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
393115001590	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115001591	S-adenosylmethionine binding site [chemical binding]; other site
393115001592	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
393115001593	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
393115001594	FMN binding site [chemical binding]; other site
393115001595	active site
393115001596	catalytic residues [active]
393115001597	substrate binding site [chemical binding]; other site
393115001598	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
393115001599	Similar to Q8KDY9 Hypothetical protein CT0905 from (173 aa). opt: 268 Z-score: 346.0 E(): 2e-11 Smith-Waterman score: 268; 54.795 identity in 73 aa overlap. Contains no start codon due to a deletion at N-terminal ORF ftt0521
393115001600	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
393115001601	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
393115001602	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
393115001603	putative active site [active]
393115001604	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
393115001605	AAA domain; Region: AAA_21; pfam13304
393115001606	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
393115001607	Walker A/P-loop; other site
393115001608	Walker A/P-loop; other site
393115001609	ATP binding site [chemical binding]; other site
393115001610	ATP binding site [chemical binding]; other site
393115001611	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
393115001612	Walker B; other site
393115001613	D-loop; other site
393115001614	H-loop/switch region; other site
393115001615	Similar to Q87Y22 DNA polymerase IV from pseudomonas syringae (353 aa). FASTA: opt: 1041 Z-score: 1243.0 E(): 2.4e-61 Smith-Waterman score: 1041; 49.153 identity in 354 aa overlap. Contains a frameshift after aa 128
393115001616	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
393115001617	DJ-1 family protein; Region: not_thiJ; TIGR01383
393115001618	conserved cys residue [active]
393115001619	Similar to Q8DCS3 ATPase component of ABC transporter with duplicated ATPase domains from Vibrio vulnificus (640 aa). FASTA: opt: 1907 Z-score: 1707.3 E(): 3.3e-87 Smith-Waterman score: 1907; 46.468 identity in 637 aa overlap. Contains a frameshift after aa 65 ORF ftt0531
393115001620	bifunctional gluaredoxin/ribonucleoside-diphosphate reductase subunit beta; Provisional; Region: PRK12759
393115001621	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
393115001622	GSH binding site [chemical binding]; other site
393115001623	catalytic residues [active]
393115001624	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
393115001625	dimer interface [polypeptide binding]; other site
393115001626	putative radical transfer pathway; other site
393115001627	diiron center [ion binding]; other site
393115001628	tyrosyl radical; other site
393115001629	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
393115001630	GSH binding site [chemical binding]; other site
393115001631	catalytic residues [active]
393115001632	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09102
393115001633	Class I ribonucleotide reductase; Region: RNR_I; cd01679
393115001634	active site
393115001635	dimer interface [polypeptide binding]; other site
393115001636	catalytic residues [active]
393115001637	effector binding site; other site
393115001638	R2 peptide binding site; other site
393115001639	malate dehydrogenase; Reviewed; Region: PRK06223
393115001640	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
393115001641	NAD(P) binding site [chemical binding]; other site
393115001642	dimer interface [polypeptide binding]; other site
393115001643	tetramer (dimer of dimers) interface [polypeptide binding]; other site
393115001644	substrate binding site [chemical binding]; other site
393115001645	Demethoxyubiquinone hydroxylase, ferritin-like diiron-binding domain; Region: DMQH; cd01042
393115001646	diiron binding motif [ion binding]; other site
393115001647	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
393115001648	N-acetyl-D-glucosamine binding site [chemical binding]; other site
393115001649	catalytic residue [active]
393115001650	Similar to Q8XPA8 Hypothetical protein CPE0057 from Clostridium perfringens (253 aa). FASTA: opt: 568 Z-score: 689.2 E(): 1.7e-30 Smith-Waterman score: 568; 46.961 identity in 181 aa overlap. Contains an in-frame stop codon after aa 181 ORF ftt0539c
393115001651	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
393115001652	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
393115001653	motif II; other site
393115001654	Similar to Q88NW9 Antioxidant,AhpC/Tsa family from Pseudomonas putida (200 aa). FASTA: opt: 979 Z-score: 1280.5 E(): 2e-63 Smith-Waterman score: 979; 72.680 identity in 194 aa overlap. Contains a frameshift after aa 108 unknown EC_number 1.6.4.- ORF ftt0542
393115001655	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
393115001656	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
393115001657	PhnA protein; Region: PhnA; pfam03831
393115001658	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
393115001659	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
393115001660	active site
393115001661	catalytic site [active]
393115001662	substrate binding site [chemical binding]; other site
393115001663	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
393115001664	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
393115001665	Similar to Q92LL0 Hypothetical protein R03032 from Rhizobium meliloti (367 aa). FASTA: opt: 921 Z-score: 1129.8 E(): 4.9e-55 Smith-Waterman score: 921; 44.186 identity in 344 aa overlap. Contains a frameshift after aa 102. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift. ORF ftt0551
393115001666	aldehyde dehydrogenase family 7 member; Region: PLN02315
393115001667	NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B; Region: ALDH_F7_AASADH; cd07130
393115001668	tetrameric interface [polypeptide binding]; other site
393115001669	NAD binding site [chemical binding]; other site
393115001670	catalytic residues [active]
393115001671	Domain of unknown function (DUF1338); Region: DUF1338; pfam07063
393115001672	Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cd10148
393115001673	putative homodimer interface [polypeptide binding]; other site
393115001674	putative homotetramer interface [polypeptide binding]; other site
393115001675	putative allosteric switch controlling residues; other site
393115001676	putative metal binding site [ion binding]; other site
393115001677	putative homodimer-homodimer interface [polypeptide binding]; other site
393115001678	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
393115001679	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
393115001680	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
393115001681	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
393115001682	dimerization interface [polypeptide binding]; other site
393115001683	Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5...; Region: PRX5_like; cd03013
393115001684	catalytic triad [active]
393115001685	dimer interface [polypeptide binding]; other site
393115001686	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
393115001687	Lin1944 and related proteins, classical (c) SDRs; Region: Lin1944_like_SDR_c; cd11731
393115001688	putative NAD(P) binding site [chemical binding]; other site
393115001689	homodimer interface [polypeptide binding]; other site
393115001690	cytidylate kinase; Provisional; Region: cmk; PRK00023
393115001691	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
393115001692	CMP-binding site; other site
393115001693	The sites determining sugar specificity; other site
393115001694	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
393115001695	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115001696	catalytic residue [active]
393115001697	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115001698	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115001699	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115001700	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
393115001701	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
393115001702	Walker A/P-loop; other site
393115001703	ATP binding site [chemical binding]; other site
393115001704	Q-loop/lid; other site
393115001705	ABC transporter signature motif; other site
393115001706	Walker B; other site
393115001707	D-loop; other site
393115001708	H-loop/switch region; other site
393115001709	TOBE domain; Region: TOBE_2; pfam08402
393115001710	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
393115001711	dimer interface [polypeptide binding]; other site
393115001712	conserved gate region; other site
393115001713	putative PBP binding loops; other site
393115001714	ABC-ATPase subunit interface; other site
393115001715	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
393115001716	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
393115001717	dimer interface [polypeptide binding]; other site
393115001718	conserved gate region; other site
393115001719	putative PBP binding loops; other site
393115001720	ABC-ATPase subunit interface; other site
393115001721	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
393115001722	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115001723	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
393115001724	Similar to Q83DZ8 Proton/peptide symporter family protein from Coxiella burnetii (504 aa). FASTA: opt: 434 Z-score: 486.3 E(): 3.4e-19 Smith-Waterman score: 434; 22.400identity in 500 aa overlap. Contains 2 frameshifts after aa 102 and 334 ORF ftt0567c
393115001725	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
393115001726	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
393115001727	motif II; other site
393115001728	hypothetical protein; Provisional; Region: PRK14013
393115001729	Protein of unknown function (DUF3301); Region: DUF3301; pfam11743
393115001730	GST_N family, Metaxin subfamily, Metaxin-like proteins; a heterogenous group of proteins, predominantly uncharacterized, with similarity to metaxins and GSTs. Metaxin 1 is a component of a preprotein import complex of the mitochondrial outer membrane. It...; Region: GST_N_Metaxin_like; cd03080
393115001731	putative C-terminal domain interface [polypeptide binding]; other site
393115001732	putative GSH binding site [chemical binding]; other site
393115001733	putative dimer interface [polypeptide binding]; other site
393115001734	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
393115001735	dimer interface [polypeptide binding]; other site
393115001736	substrate binding pocket (H-site) [chemical binding]; other site
393115001737	C-terminal, alpha helical domain of Metaxin and related proteins; Region: GST_C_Metaxin; cd03193
393115001738	putative N-terminal domain interface [polypeptide binding]; other site
393115001739	POT family; Region: PTR2; cl17359
393115001740	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
393115001741	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
393115001742	active site
393115001743	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
393115001744	dimer interface [polypeptide binding]; other site
393115001745	substrate binding site [chemical binding]; other site
393115001746	catalytic residues [active]
393115001747	Similar to Q83AT4 Amino acid permease family protein from Coxiella burnetii (542 aa). FASTA: opt: 1289 Z-score: 1363.6 E(): 4.6e-68 Smith-Waterman score: 1289; 42.534 identity in 442 aa overlap. Contains an in-frame stop codon after aa 284 and a frameshift after aa 445 ORF ftt0574
393115001748	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
393115001749	Prephenate dehydratase; Region: PDT; pfam00800
393115001750	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
393115001751	putative L-Phe binding site [chemical binding]; other site
393115001752	Protein of unknown function DUF45; Region: DUF45; pfam01863
393115001753	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
393115001754	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
393115001755	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
393115001756	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
393115001757	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
393115001758	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115001759	catalytic residue [active]
393115001760	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
393115001761	probable FeS assembly SUF system protein SufT; Region: FeS_long_SufT; TIGR03406
393115001762	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
393115001763	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
393115001764	active site
393115001765	(T/H)XGH motif; other site
393115001766	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
393115001767	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
393115001768	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
393115001769	ligand binding site [chemical binding]; other site
393115001770	CRISPR/Cas system-associated protein Cas9; Region: Csx12; cd09704
393115001771	CRISPR-associated protein Cas9/Csx12, subtype II-B/NMENI; Region: cas_csx12; TIGR03031
393115001772	Similar to Q99YS7 Hypothetical protein SPy1562 from Streptococcus pyogenes (341 aa). FASTA: opt: 377 Z-score: 453.0 E(): 2.4e-17 Smith-Waterman score: 377; 28.526 identity in 312 aa overlap. Contains a frameshift after aa 181 ORF ftt0585
393115001773	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
393115001774	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
393115001775	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115001776	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
393115001777	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
393115001778	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
393115001779	hinge; other site
393115001780	active site
393115001781	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
393115001782	RNA/DNA hybrid binding site [nucleotide binding]; other site
393115001783	active site
393115001784	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
393115001785	active site
393115001786	homodimer interface [polypeptide binding]; other site
393115001787	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
393115001788	active site clefts [active]
393115001789	zinc binding site [ion binding]; other site
393115001790	dimer interface [polypeptide binding]; other site
393115001791	1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism]; Region: Acd; COG2515
393115001792	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
393115001793	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115001794	catalytic residue [active]
393115001795	Rubredoxin [Energy production and conversion]; Region: COG1773
393115001796	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
393115001797	iron binding site [ion binding]; other site
393115001798	Uncharacterized conserved protein [Function unknown]; Region: COG0397
393115001799	hypothetical protein; Validated; Region: PRK00029
393115001800	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
393115001801	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
393115001802	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
393115001803	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
393115001804	dimer interface [polypeptide binding]; other site
393115001805	active site
393115001806	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
393115001807	dimer interface [polypeptide binding]; other site
393115001808	active site
393115001809	Similar to Q8G3X1 D-xylose-proton symporter from Bifodobacterium longum (517 aa). FASTA: opt: 795 Z-score: 849.1 E(): 2.1e-39 Smith-Waterman score: 795; 33.040 identity in 454 aa overlap. Contains a frameshift after aa 401 ORF ftt0600
393115001810	Protein of unknown function (DUF3573); Region: DUF3573; pfam12097
393115001811	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
393115001812	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
393115001813	Similar to Q8KTX3 Putative YbgI protein from Vibrio fischeri (251 aa). FASTA: opt: 818 Z-score: 1022.1 E(): 4.9e-49 Smith-Waterman score: 818; 53.112 identity in 241 aa overlap. Contains a frameshift after aa 140 ORF ftt0606c
393115001814	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
393115001815	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
393115001816	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
393115001817	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
393115001818	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
393115001819	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
393115001820	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
393115001821	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
393115001822	active site
393115001823	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
393115001824	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
393115001825	active site
393115001826	substrate binding site [chemical binding]; other site
393115001827	Mg2+ binding site [ion binding]; other site
393115001828	beta-lactamase TEM; Provisional; Region: PRK15442
393115001829	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
393115001830	VirK protein; Region: VirK; pfam06903
393115001831	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
393115001832	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
393115001833	putative active site [active]
393115001834	catalytic triad [active]
393115001835	putative dimer interface [polypeptide binding]; other site
393115001836	FOG: CBS domain [General function prediction only]; Region: COG0517
393115001837	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
393115001838	Transporter associated domain; Region: CorC_HlyC; smart01091
393115001839	metal-binding heat shock protein; Provisional; Region: PRK00016
393115001840	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
393115001841	PhoH-like protein; Region: PhoH; pfam02562
393115001842	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
393115001843	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
393115001844	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
393115001845	FeS/SAM binding site; other site
393115001846	TRAM domain; Region: TRAM; pfam01938
393115001847	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
393115001848	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
393115001849	HAD superfamily, subfamily IIIB (Acid phosphatase); Region: Acid_phosphat_B; cl17236
393115001850	thymidine kinase; Provisional; Region: PRK04296
393115001851	trigger factor; Provisional; Region: tig; PRK01490
393115001852	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
393115001853	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
393115001854	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
393115001855	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
393115001856	oligomer interface [polypeptide binding]; other site
393115001857	active site residues [active]
393115001858	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
393115001859	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
393115001860	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115001861	Walker A motif; other site
393115001862	ATP binding site [chemical binding]; other site
393115001863	Walker B motif; other site
393115001864	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
393115001865	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
393115001866	Found in ATP-dependent protease La (LON); Region: LON; smart00464
393115001867	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115001868	Walker A motif; other site
393115001869	ATP binding site [chemical binding]; other site
393115001870	Walker B motif; other site
393115001871	arginine finger; other site
393115001872	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
393115001873	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
393115001874	IHF dimer interface [polypeptide binding]; other site
393115001875	IHF - DNA interface [nucleotide binding]; other site
393115001876	SurA N-terminal domain; Region: SurA_N_3; cl07813
393115001877	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
393115001878	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
393115001879	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
393115001880	bacterial Hfq-like; Region: Hfq; cd01716
393115001881	hexamer interface [polypeptide binding]; other site
393115001882	Sm1 motif; other site
393115001883	RNA binding site [nucleotide binding]; other site
393115001884	Sm2 motif; other site
393115001885	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
393115001886	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
393115001887	HflX GTPase family; Region: HflX; cd01878
393115001888	G1 box; other site
393115001889	GTP/Mg2+ binding site [chemical binding]; other site
393115001890	Switch I region; other site
393115001891	G2 box; other site
393115001892	G3 box; other site
393115001893	Switch II region; other site
393115001894	G4 box; other site
393115001895	G5 box; other site
393115001896	hypothetical protein; Provisional; Region: PRK07588
393115001897	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
393115001898	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
393115001899	HflK protein; Region: hflK; TIGR01933
393115001900	FtsH protease regulator HflC; Provisional; Region: PRK11029
393115001901	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
393115001902	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
393115001903	Low molecular weight phosphatase family; Region: LMWPc; cd00115
393115001904	active site
393115001905	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
393115001906	G1 box; other site
393115001907	GTP/Mg2+ binding site [chemical binding]; other site
393115001908	Switch I region; other site
393115001909	G2 box; other site
393115001910	G3 box; other site
393115001911	Switch II region; other site
393115001912	G4 box; other site
393115001913	G5 box; other site
393115001914	Similar to THRC_METJA (Q58860) Probable threonine synthase (405 aa). FASTA: opt: opt: 987 Z-score: 1131.2 E(): 3.7e-55 Smith-Waterman score: 987; 44.875 identity in 361 aa overlap. Contains 2 frameshifts after aa 121 and 247
393115001915	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
393115001916	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; cl07212
393115001917	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
393115001918	Similar to Q8A609 Acetolactate synthase large subunit from Bacteroides thetaiotaomicron (565 aa). FASTA: opt: 1850 Z-score: 2038.0 E(): 1.1e-105 Smith-Waterman score: 1850; 50.089 identity in 559 aa overlap. Contains a frameshift after aa 427
393115001919	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
393115001920	putative valine binding site [chemical binding]; other site
393115001921	dimer interface [polypeptide binding]; other site
393115001922	Similar to Q847R5 Ketol acid reductoisomerase mitochondrial from Aster yellows phytoplasma (344 aa). FASTA: opt: 1145 Z-score: 1365.8 E(): 3.5e-68 Smith-Waterman score: 1448; 62.391identity in 343 aa overlap. Contains a frameshift after aa 37 and an in-frame stop codon after aa 74
393115001923	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
393115001924	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
393115001925	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
393115001926	ATP binding site [chemical binding]; other site
393115001927	putative Mg++ binding site [ion binding]; other site
393115001928	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115001929	nucleotide binding region [chemical binding]; other site
393115001930	ATP-binding site [chemical binding]; other site
393115001931	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
393115001932	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
393115001933	YccA-like proteins; Region: YccA_like; cd10433
393115001934	Domain of unknown function (DUF1841); Region: DUF1841; pfam08897
393115001935	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
393115001936	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
393115001937	minor groove reading motif; other site
393115001938	helix-hairpin-helix signature motif; other site
393115001939	substrate binding pocket [chemical binding]; other site
393115001940	active site
393115001941	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
393115001942	ferredoxin; Provisional; Region: PRK08764
393115001943	Putative Fe-S cluster; Region: FeS; cl17515
393115001944	4Fe-4S binding domain; Region: Fer4; pfam00037
393115001945	glutaredoxin 2; Provisional; Region: PRK10387
393115001946	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
393115001947	C-terminal domain interface [polypeptide binding]; other site
393115001948	GSH binding site (G-site) [chemical binding]; other site
393115001949	catalytic residues [active]
393115001950	putative dimer interface [polypeptide binding]; other site
393115001951	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
393115001952	N-terminal domain interface [polypeptide binding]; other site
393115001953	POT family; Region: PTR2; cl17359
393115001954	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
393115001955	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
393115001956	Ferritin-like domain; Region: Ferritin; pfam00210
393115001957	ferroxidase diiron center [ion binding]; other site
393115001958	lipoyl synthase; Provisional; Region: PRK05481
393115001959	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
393115001960	FeS/SAM binding site; other site
393115001961	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
393115001962	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
393115001963	conserved cys residue [active]
393115001964	hypothetical protein; Validated; Region: PRK00110
393115001965	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
393115001966	active site
393115001967	putative DNA-binding cleft [nucleotide binding]; other site
393115001968	dimer interface [polypeptide binding]; other site
393115001969	Similar to AAO90981 (Q83BM0) Major facilitator family transporter from coxiella burnetti (428 aa). FASTA: opt: 586 Z-score: 650.3 E(): 2.3e-28 Smith-Waterman score: 600; 27.638 identity in 398 aa overlap. Contains 2 in-frame stop codons after aa 65 and 190 ORF ftt0657
393115001970	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
393115001971	RuvA N terminal domain; Region: RuvA_N; pfam01330
393115001972	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
393115001973	RmuC family; Region: RmuC; pfam02646
393115001974	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
393115001975	dimerization interface [polypeptide binding]; other site
393115001976	putative Zn2+ binding site [ion binding]; other site
393115001977	putative DNA binding site [nucleotide binding]; other site
393115001978	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4337
393115001979	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
393115001980	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
393115001981	histidine decarboxylase; Provisional; Region: PRK02769
393115001982	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115001983	catalytic residue [active]
393115001984	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
393115001985	intersubunit interface [polypeptide binding]; other site
393115001986	active site
393115001987	Zn2+ binding site [ion binding]; other site
393115001988	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
393115001989	active site
393115001990	DNA binding site [nucleotide binding]
393115001991	Isochorismatase family; Region: Isochorismatase; pfam00857
393115001992	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
393115001993	catalytic triad [active]
393115001994	conserved cis-peptide bond; other site
393115001995	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
393115001996	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
393115001997	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
393115001998	Mechanosensitive ion channel; Region: MS_channel; pfam00924
393115001999	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115002000	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115002001	putative substrate translocation pore; other site
393115002002	Similar to Q83BM0 Major facilitator family transporter from Coxiella burnetii (428 aa). FASTA: opt: 549 Z-score: 638.7 E(): 1.1e-27 Smith-Waterman score: 549; 26.353 identity in 425 aa overlap. Contains a frameshift after aa 109 ORF ftt0672c
393115002003	Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup; Region: M14_ASTE_ASPA_like_1; cd06251
393115002004	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
393115002005	putative active site [active]
393115002006	Zn binding site [ion binding]; other site
393115002007	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
393115002008	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
393115002009	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
393115002010	active site
393115002011	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
393115002012	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
393115002013	5S rRNA interface [nucleotide binding]; other site
393115002014	CTC domain interface [polypeptide binding]; other site
393115002015	L16 interface [polypeptide binding]; other site
393115002016	Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism]; Region: CorB; COG4536
393115002017	Domain of unknown function DUF21; Region: DUF21; pfam01595
393115002018	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
393115002019	Transporter associated domain; Region: CorC_HlyC; pfam03471
393115002020	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
393115002021	Methyltransferase domain; Region: Methyltransf_31; pfam13847
393115002022	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115002023	S-adenosylmethionine binding site [chemical binding]; other site
393115002024	GTP-binding protein YchF; Reviewed; Region: PRK09601
393115002025	YchF GTPase; Region: YchF; cd01900
393115002026	G1 box; other site
393115002027	GTP/Mg2+ binding site [chemical binding]; other site
393115002028	Switch I region; other site
393115002029	G2 box; other site
393115002030	Switch II region; other site
393115002031	G3 box; other site
393115002032	G4 box; other site
393115002033	G5 box; other site
393115002034	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
393115002035	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
393115002036	putative active site [active]
393115002037	catalytic residue [active]
393115002038	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
393115002039	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
393115002040	dimerization domain [polypeptide binding]; other site
393115002041	dimer interface [polypeptide binding]; other site
393115002042	catalytic residues [active]
393115002043	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
393115002044	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
393115002045	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
393115002046	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
393115002047	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
393115002048	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
393115002049	voltage-gated potassium channel; Provisional; Region: PRK10537
393115002050	Ion channel; Region: Ion_trans_2; pfam07885
393115002051	POT family; Region: PTR2; cl17359
393115002052	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
393115002053	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115002054	Walker A motif; other site
393115002055	ATP binding site [chemical binding]; other site
393115002056	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
393115002057	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
393115002058	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
393115002059	active site
393115002060	HslU subunit interaction site [polypeptide binding]; other site
393115002061	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
393115002062	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
393115002063	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
393115002064	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
393115002065	active site
393115002066	HIGH motif; other site
393115002067	dimer interface [polypeptide binding]; other site
393115002068	KMSKS motif; other site
393115002069	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
393115002070	RNA binding surface [nucleotide binding]; other site
393115002071	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115002072	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115002073	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115002074	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
393115002075	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
393115002076	DNA binding site [nucleotide binding]
393115002077	catalytic residue [active]
393115002078	H2TH interface [polypeptide binding]; other site
393115002079	putative catalytic residues [active]
393115002080	turnover-facilitating residue; other site
393115002081	intercalation triad [nucleotide binding]; other site
393115002082	8OG recognition residue [nucleotide binding]; other site
393115002083	putative reading head residues; other site
393115002084	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
393115002085	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
393115002086	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
393115002087	AMP-binding enzyme; Region: AMP-binding; pfam00501
393115002088	acyl-activating enzyme (AAE) consensus motif; other site
393115002089	putative AMP binding site [chemical binding]; other site
393115002090	MraW methylase family; Region: Methyltransf_5; cl17771
393115002091	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
393115002092	Cell division protein FtsL; Region: FtsL; cl11433
393115002093	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
393115002094	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
393115002095	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
393115002096	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
393115002097	16S/18S rRNA binding site [nucleotide binding]; other site
393115002098	S13e-L30e interaction site [polypeptide binding]; other site
393115002099	25S rRNA binding site [nucleotide binding]; other site
393115002100	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
393115002101	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
393115002102	oligomer interface [polypeptide binding]; other site
393115002103	RNA binding site [nucleotide binding]; other site
393115002104	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
393115002105	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
393115002106	RNase E interface [polypeptide binding]; other site
393115002107	trimer interface [polypeptide binding]; other site
393115002108	active site
393115002109	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
393115002110	putative nucleic acid binding region [nucleotide binding]; other site
393115002111	G-X-X-G motif; other site
393115002112	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
393115002113	RNA binding site [nucleotide binding]; other site
393115002114	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
393115002115	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
393115002116	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
393115002117	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
393115002118	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
393115002119	ATP-binding site [chemical binding]; other site
393115002120	Sugar specificity; other site
393115002121	Pyrimidine base specificity; other site
393115002122	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
393115002123	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
393115002124	TRAM domain; Region: TRAM; pfam01938
393115002125	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115002126	S-adenosylmethionine binding site [chemical binding]; other site
393115002127	Similar to Q8EQ10 Glucose kinase (EC 2.7.1.2) from Oceanobacillus iheyensis (325 aa). FASTA: opt: 569 Z-score: 642.8 E(): 6.5e-28 Smith-Waterman score: 569; 31.111 identity in 315 aa overlap. Contains a frameshift after aa 254
393115002128	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
393115002129	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115002130	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115002131	putative substrate translocation pore; other site
393115002132	enolase; Provisional; Region: eno; PRK00077
393115002133	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
393115002134	dimer interface [polypeptide binding]; other site
393115002135	metal binding site [ion binding]; metal-binding site
393115002136	substrate binding pocket [chemical binding]; other site
393115002137	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
393115002138	Septum formation initiator; Region: DivIC; cl17659
393115002139	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
393115002140	substrate binding site; other site
393115002141	dimer interface; other site
393115002142	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
393115002143	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
393115002144	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
393115002145	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
393115002146	NAD(P) binding site [chemical binding]; other site
393115002147	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
393115002148	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
393115002149	substrate-cofactor binding pocket; other site
393115002150	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115002151	catalytic residue [active]
393115002152	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
393115002153	Glyco_18 domain; Region: Glyco_18; smart00636
393115002154	active site
393115002155	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
393115002156	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
393115002157	aromatic chitin/cellulose binding site residues [chemical binding]; other site
393115002158	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
393115002159	aromatic chitin/cellulose binding site residues [chemical binding]; other site
393115002160	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
393115002161	active site
393115002162	Similar to Q9KQK6 Formyltetrahydrofolate deformylase (277 aa). FASTA: opt: 1088 Z-score: 1353.6 E(): 1.7e-67 Smith-Waterman score: 1088; 59.206 identity in 277 aa overlap. Contains a frameshift after aa 81. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift
393115002163	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
393115002164	putative substrate binding pocket [chemical binding]; other site
393115002165	trimer interface [polypeptide binding]; other site
393115002166	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115002167	metabolite-proton symporter; Region: 2A0106; TIGR00883
393115002168	putative substrate translocation pore; other site
393115002169	dGTP triphosphohydrolase [Nucleotide transport and metabolism]; Region: Dgt; COG0232
393115002170	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
393115002171	Zn2+ binding site [ion binding]; other site
393115002172	Mg2+ binding site [ion binding]; other site
393115002173	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
393115002174	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
393115002175	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
393115002176	heme binding site [chemical binding]; other site
393115002177	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
393115002178	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115002179	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115002180	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115002181	classical (c) SDRs; Region: SDR_c; cd05233
393115002182	NAD(P) binding site [chemical binding]; other site
393115002183	active site
393115002184	Similar to Q8EEI8 Penicillin-binding protein 4 from Shewanella oneidensis (507 aa) aa). FASTA: opt: 645 Z-score: 721.3 E(): 2.5e-32 Smith-Waterman score: 645; 31.478identity in 467 aa overlap. Contains a frameshift after aa 136. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift
393115002185	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
393115002186	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115002187	putative substrate translocation pore; other site
393115002188	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
393115002189	Glycerophosphodiester phosphodiesterase domain of putative Silicibacter pomeroyi glycerophosphodiester phosphodiesterase and similar proteins; Region: GDPD_SpGDE_like; cd08567
393115002190	active site
393115002191	catalytic site [active]
393115002192	metal binding site [ion binding]; metal-binding site
393115002193	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
393115002194	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
393115002195	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
393115002196	Walker A/P-loop; other site
393115002197	ATP binding site [chemical binding]; other site
393115002198	Q-loop/lid; other site
393115002199	ABC transporter signature motif; other site
393115002200	Walker B; other site
393115002201	D-loop; other site
393115002202	H-loop/switch region; other site
393115002203	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
393115002204	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
393115002205	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
393115002206	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115002207	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
393115002208	Chorismate mutase type II; Region: CM_2; smart00830
393115002209	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
393115002210	catalytic residues [active]
393115002211	dimer interface [polypeptide binding]; other site
393115002212	Similar to Q9K8K1 Hypothetical protein BH3005 from Bacillus halodurans (388 aa). FASTA: opt: 934 Z-score: 1058.9 E(): 4.3e-51 Smith-Waterman score: 934; 38.144 identity in 388 aa overlap. Contains an in-frame stop codon after aa 187 ORF ftt0734
393115002213	Similar to Q81CC3 Mandelate racemase/muconate lactonizing enzyme family protein Bacillus cereus (strain ATCC 14579 / DSM 31) (350 aa). FASTA: opt: 653 Z-score: 766.5 E(): 8.4e-35 Smith-Waterman score: 653; 34.877identity in 324 aa overlap. Contains 2 in-frame stop codons after aa 84 and 199 ORF ftt0735
393115002214	Putative serine esterase (DUF676); Region: DUF676; pfam05057
393115002215	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
393115002216	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
393115002217	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
393115002218	putative substrate binding site [chemical binding]; other site
393115002219	putative ATP binding site [chemical binding]; other site
393115002220	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
393115002221	RNA binding surface [nucleotide binding]; other site
393115002222	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
393115002223	OstA-like protein; Region: OstA; cl00844
393115002224	Organic solvent tolerance protein; Region: OstA_C; pfam04453
393115002225	Protein of unknown function (DUF2797); Region: DUF2797; pfam10977
393115002226	Fusaric acid resistance protein family; Region: FUSC; pfam04632
393115002227	Fusaric acid resistance protein family; Region: FUSC; pfam04632
393115002228	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
393115002229	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
393115002230	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
393115002231	HlyD family secretion protein; Region: HlyD_3; pfam13437
393115002232	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
393115002233	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
393115002234	non-specific DNA interactions [nucleotide binding]; other site
393115002235	DNA binding site [nucleotide binding]
393115002236	sequence specific DNA binding site [nucleotide binding]; other site
393115002237	putative cAMP binding site [chemical binding]; other site
393115002238	Bacterial transcriptional regulator; Region: IclR; pfam01614
393115002239	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
393115002240	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
393115002241	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
393115002242	Radical SAM superfamily; Region: Radical_SAM; pfam04055
393115002243	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
393115002244	FeS/SAM binding site; other site
393115002245	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
393115002246	DNA-binding site [nucleotide binding]; DNA binding site
393115002247	RNA-binding motif; other site
393115002248	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
393115002249	Protein of unknown function with HXXEE motif; Region: HXXEE; pfam13787
393115002250	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
393115002251	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
393115002252	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
393115002253	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
393115002254	active site
393115002255	tetramer interface; other site
393115002256	Similar to Q92KX2 Probable acetyl-coenzyme A synthetase 2 from Rhizobium meliloti (Sinorhizobium meliloti) (649 aa). FASTA: opt: 1346 Z-score: 1602.8 E(): 2.2e-81 Smith-Waterman score: 1424; 39.908 identity in 649 aa overlap. Contains an internal deletion after aa 134 that causes a corresponding frameshift
393115002257	EamA-like transporter family; Region: EamA; pfam00892
393115002258	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
393115002259	EamA-like transporter family; Region: EamA; pfam00892
393115002260	Protein of unknown function (DUF1311); Region: DUF1311; cl01530
393115002261	recombination protein F; Reviewed; Region: recF; PRK00064
393115002262	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
393115002263	Walker A/P-loop; other site
393115002264	ATP binding site [chemical binding]; other site
393115002265	Q-loop/lid; other site
393115002266	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
393115002267	ABC transporter signature motif; other site
393115002268	Walker B; other site
393115002269	D-loop; other site
393115002270	H-loop/switch region; other site
393115002271	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
393115002272	active site
393115002273	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
393115002274	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
393115002275	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115002276	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115002277	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115002278	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
393115002279	LPP20 lipoprotein; Region: LPP20; cl15824
393115002280	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
393115002281	DEAD/DEAH box helicase; Region: DEAD; pfam00270
393115002282	ATP binding site [chemical binding]; other site
393115002283	putative Mg++ binding site [ion binding]; other site
393115002284	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
393115002285	SEC-C motif; Region: SEC-C; pfam02810
393115002286	Similar to Q83EE1 DNA-3-methyladenine glycosidase I from Coxiella burnetii (204 aa). FASTA: opt: 668 Z-score: 863.4 E(): 3.4e-40 Smith-Waterman score: 668; 52.459 identity in 183 aa overlap. Contains an in-frame stop codon after aa 66
393115002287	Similar to GRK_BACHD (Q9Z9P2) Glycerate kinase from Bacillus halodurans (380 aa). FASTA: opt: 992 Z-score: 1181.8 E(): 6.2e-58 Smith-Waterman score: 992; 41.600 identity in 375 aa overlap. Contains 2 frameshifts after aa 136 and 332
393115002288	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
393115002289	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
393115002290	Uncharacterized protein conserved in bacteria (DUF2237); Region: DUF2237; pfam09996
393115002291	Similar to Q81IY9 Bicyclomycin resistance protein from Bacillus cereus (strain ATCC 14579 / DSM 31) (416 aa). FASTA: opt: 598 Z-score: 663.2 E(): 4.7e-29 Smith-Waterman score: 598; 28.960 identity in 404 aa overlap. Contains a frameshift after aa 103 Putative drug transport protein.
393115002292	ribonuclease D; Region: rnd; TIGR01388
393115002293	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
393115002294	catalytic site [active]
393115002295	putative active site [active]
393115002296	putative substrate binding site [chemical binding]; other site
393115002297	HRDC domain; Region: HRDC; pfam00570
393115002298	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
393115002299	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
393115002300	GIY-YIG motif/motif A; other site
393115002301	active site
393115002302	catalytic site [active]
393115002303	putative DNA binding site [nucleotide binding]; other site
393115002304	metal binding site [ion binding]; metal-binding site
393115002305	UvrB/uvrC motif; Region: UVR; pfam02151
393115002306	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
393115002307	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115002308	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115002309	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115002310	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
393115002311	Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623
393115002312	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
393115002313	NAD binding site [chemical binding]; other site
393115002314	homotetramer interface [polypeptide binding]; other site
393115002315	homodimer interface [polypeptide binding]; other site
393115002316	substrate binding site [chemical binding]; other site
393115002317	active site
393115002318	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
393115002319	hypothetical protein; Provisional; Region: PRK05409
393115002320	Uncharacterized protein conserved in bacteria (DUF2063); Region: DUF2063; pfam09836
393115002321	DoxX; Region: DoxX; pfam07681
393115002322	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
393115002323	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
393115002324	putative active site [active]
393115002325	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
393115002326	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
393115002327	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
393115002328	substrate binding site [chemical binding]; other site
393115002329	hexamer interface [polypeptide binding]; other site
393115002330	metal binding site [ion binding]; metal-binding site
393115002331	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
393115002332	Bacterial sugar transferase; Region: Bac_transf; pfam02397
393115002333	UDP-glucose 4-epimerase; Region: PLN02240
393115002334	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
393115002335	NAD binding site [chemical binding]; other site
393115002336	homodimer interface [polypeptide binding]; other site
393115002337	active site
393115002338	substrate binding site [chemical binding]; other site
393115002339	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
393115002340	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_4; cd03795
393115002341	putative ADP-binding pocket [chemical binding]; other site
393115002342	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
393115002343	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
393115002344	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
393115002345	Walker A/P-loop; other site
393115002346	ATP binding site [chemical binding]; other site
393115002347	Q-loop/lid; other site
393115002348	ABC transporter signature motif; other site
393115002349	Walker B; other site
393115002350	D-loop; other site
393115002351	H-loop/switch region; other site
393115002352	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
393115002353	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
393115002354	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
393115002355	active site
393115002356	Methyltransferase domain; Region: Methyltransf_23; pfam13489
393115002357	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115002358	S-adenosylmethionine binding site [chemical binding]; other site
393115002359	LicD family; Region: LicD; pfam04991
393115002360	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
393115002361	active site
393115002362	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
393115002363	active site
393115002364	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
393115002365	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
393115002366	pyrimidine 5'-nucleotidase; Region: Pyr-5-nucltdase; TIGR01993
393115002367	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
393115002368	motif II; other site
393115002369	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
393115002370	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
393115002371	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
393115002372	substrate binding site [chemical binding]; other site
393115002373	ATP binding site [chemical binding]; other site
393115002374	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
393115002375	proposed catalytic triad [active]
393115002376	active site nucleophile [active]
393115002377	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
393115002378	catalytic nucleophile [active]
393115002379	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115002380	metabolite-proton symporter; Region: 2A0106; TIGR00883
393115002381	putative substrate translocation pore; other site
393115002382	poly-gamma-glutamate synthase PgsB/CapB; Region: poly_gGlu_PgsB; TIGR04012
393115002383	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115002384	poly-gamma-glutamate biosynthesis protein PgsC/CapC; Region: poly_gGlu_PgsC; TIGR04011
393115002385	poly-gamma-glutamate system protein; Region: gamma_Glu_sys; TIGR04332
393115002386	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
393115002387	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
393115002388	Zn2+ binding site [ion binding]; other site
393115002389	Mg2+ binding site [ion binding]; other site
393115002390	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
393115002391	synthetase active site [active]
393115002392	NTP binding site [chemical binding]; other site
393115002393	metal binding site [ion binding]; metal-binding site
393115002394	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
393115002395	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
393115002396	recombination protein RecR; Provisional; Region: PRK13844
393115002397	RecR protein; Region: RecR; pfam02132
393115002398	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
393115002399	putative active site [active]
393115002400	putative metal-binding site [ion binding]; other site
393115002401	tetramer interface [polypeptide binding]; other site
393115002402	hypothetical protein; Validated; Region: PRK00153
393115002403	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
393115002404	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
393115002405	homodimer interface [polypeptide binding]; other site
393115002406	active site
393115002407	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
393115002408	lipoyl attachment site [posttranslational modification]; other site
393115002409	Chitin binding domain; Region: Chitin_bind_3; pfam03067
393115002410	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
393115002411	aromatic chitin/cellulose binding site residues [chemical binding]; other site
393115002412	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
393115002413	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
393115002414	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
393115002415	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
393115002416	active site
393115002417	dimer interface [polypeptide binding]; other site
393115002418	motif 1; other site
393115002419	motif 2; other site
393115002420	motif 3; other site
393115002421	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
393115002422	anticodon binding site; other site
393115002423	translation initiation factor IF-3; Region: infC; TIGR00168
393115002424	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
393115002425	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
393115002426	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
393115002427	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
393115002428	23S rRNA binding site [nucleotide binding]; other site
393115002429	L21 binding site [polypeptide binding]; other site
393115002430	L13 binding site [polypeptide binding]; other site
393115002431	Uncharacterized conserved protein [Function unknown]; Region: COG0398
393115002432	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
393115002433	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115002434	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115002435	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115002436	Hydrolase of X-linked nucleoside diphosphate N terminal; Region: Nudix_N; pfam12535
393115002437	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_14; cd04672
393115002438	nudix motif; other site
393115002439	Arsenate Reductase (ArsC) family; composed of TRX-fold arsenic reductases and similar proteins including the transcriptional regulator, Spx. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from...; Region: ArsC_family; cd02977
393115002440	ArsC family; Region: ArsC; pfam03960
393115002441	catalytic residue [active]
393115002442	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
393115002443	Similar to Q845W8 L-aspartate-beta-decarboxylase from Pseudomonas dacunhae (533 aa). FASTA: opt: 1854 Z-score: 2243.7 E(): 4.4e-117 Smith-Waterman score: 1854; 54.476 identity in 525 aa overlap. Contains a frameshift after aa 198 ORF ftt0828c
393115002444	aspartate-alanine antiporter; Region: Asp_Ala_antiprt; TIGR03802
393115002445	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
393115002446	TrkA-C domain; Region: TrkA_C; pfam02080
393115002447	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
393115002448	Similar to Q8XJQ3 Smf protein DNA processing chain A from Clostridium perfringens (360 aa). FASTA: 754 Z-score: 848.5 E(): 2.1e-39 Smith-Waterman score: 754; 37.151identity in 358 aa overlap. Contains a frameshift after aa 153. ORF ftt0830c
393115002449	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
393115002450	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
393115002451	ligand binding site [chemical binding]; other site
393115002452	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
393115002453	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
393115002454	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
393115002455	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
393115002456	Chorismate mutase (AroH) is one of at least five chorismate-utilizing enzymes present in microorganisms that catalyze the rearrangement of chorismate to prephenic acid, the first committed step in the biosynthesis of aromatic amino acids. In prokaryotes; Region: AroH; cd02185
393115002457	homotrimer interaction site [polypeptide binding]; other site
393115002458	active site
393115002459	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
393115002460	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
393115002461	TolQ protein; Region: tolQ; TIGR02796
393115002462	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
393115002463	TolR protein; Region: tolR; TIGR02801
393115002464	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
393115002465	TolB amino-terminal domain; Region: TolB_N; pfam04052
393115002466	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
393115002467	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
393115002468	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
393115002469	ligand binding site [chemical binding]; other site
393115002470	Similar to YLIG_ECOLI Hypothetical protein yliG from Eschericia coli (441 aa). FASTA: opt: 1850 Z-score: 2204.1 E(): 7.1e-115 Smith-Waterman score: 1850; 61.136 identity in 440 aa overlap. Contains a frameshift after aa 185 ORF ftt0843
393115002471	Similar to Q9F7P6 Predicted CsgA,Rossman fold oxidoreductase from Gamma-proteobacterium EBAC31A08 (262 aa). FASTA: opt: 764 Z-score: 936.3 E(): 2.9e-44 Smith-Waterman score: 764; 53.390identity in 236 aa overlap. Contains an in-frame stop codon after aa 59 ORF ftt0844
393115002472	Protein of unknown function (DUF2805); Region: DUF2805; pfam10985
393115002473	DNA photolyase; Region: DNA_photolyase; pfam00875
393115002474	FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441
393115002475	Uncharacterized protein related to deoxyribodipyrimidine photolyase [General function prediction only]; Region: COG3046
393115002476	Deoxyribodipyrimidine photo-lyase-related protein; Region: DPRP; pfam04244
393115002477	Uncharacterized protein conserved in bacteria (DUF2256); Region: DUF2256; pfam10013
393115002478	bile acid transporter; Region: bass; TIGR00841
393115002479	Sodium Bile acid symporter family; Region: SBF; cl17470
393115002480	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
393115002481	YheO-like PAS domain; Region: PAS_6; pfam08348
393115002482	HTH domain; Region: HTH_22; pfam13309
393115002483	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
393115002484	hypothetical protein; Provisional; Region: PRK10621
393115002485	Weakly similar to Q8D5E8 Transglutaminase-like enzyme from Vibrio vulnificus (300 aa). FASTA: opt: 336 Z-score: 432.9 E(): 3.2e-16 Smith-Waterman score: 401; 29.779 identity in 272 aa overlap. Contains a frameshift after codon 183 ORF ftt0852
393115002486	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
393115002487	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
393115002488	transmembrane helices; other site
393115002489	Protein of unknown function (DUF423); Region: DUF423; pfam04241
393115002490	Protein of unknown function, DUF393; Region: DUF393; pfam04134
393115002491	4-hydroxybenzoate polyprenyltransferase; Reviewed; Region: ubiA; PRK12847
393115002492	UbiA prenyltransferase family; Region: UbiA; pfam01040
393115002493	Chorismate lyase; Region: Chor_lyase; cl01230
393115002494	ribonuclease PH; Reviewed; Region: rph; PRK00173
393115002495	Ribonuclease PH; Region: RNase_PH_bact; cd11362
393115002496	hexamer interface [polypeptide binding]; other site
393115002497	active site
393115002498	Tfp pilus assembly protein PilE [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilE; COG4968
393115002499	heat shock protein HtpX; Provisional; Region: PRK02870
393115002500	LemA family; Region: LemA; cl00742
393115002501	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
393115002502	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
393115002503	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
393115002504	putative dimerization interface [polypeptide binding]; other site
393115002505	Similar to Q83C61 Hypothetical protein from Coxiella burnetii (353 aa). FASTA: opt: 1159 Z-score: 1425.3 E(): 1.7e-71 Smith-Waterman score: 1159; 51.289 identity in 349 aa overlap. Contains a frameshift after aa 61 ORF ftt0865
393115002506	Similar to P58414 Probable cadmium-transporting ATPase from Listeria monocytogenes (707 aa). FASTA: opt: 1598 Z-score: 1734.8 E(): 8.9e-89 Smith-Waterman score: 1632; 38.324 identity in 728 aa overlap. Contains a frameshift after aa 391 and an interruption due to an IS element ORF ftt0866c
393115002507	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
393115002508	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115002509	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
393115002510	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
393115002511	dimerization interface [polypeptide binding]; other site
393115002512	putative DNA binding site [nucleotide binding]; other site
393115002513	putative Zn2+ binding site [ion binding]; other site
393115002514	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39A; cd02549
393115002515	putative active site [active]
393115002516	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
393115002517	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
393115002518	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
393115002519	Colicin V production protein; Region: Colicin_V; pfam02674
393115002520	DNA repair protein RadA; Provisional; Region: PRK11823
393115002521	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
393115002522	Walker A motif/ATP binding site; other site
393115002523	ATP binding site [chemical binding]; other site
393115002524	Walker B motif; other site
393115002525	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
393115002526	PilZ domain; Region: PilZ; pfam07238
393115002527	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
393115002528	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
393115002529	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
393115002530	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
393115002531	Tetramer interface [polypeptide binding]; other site
393115002532	active site
393115002533	FMN-binding site [chemical binding]; other site
393115002534	PQ loop repeat; Region: PQ-loop; pfam04193
393115002535	methionine sulfoxide reductase B; Provisional; Region: PRK00222
393115002536	SelR domain; Region: SelR; pfam01641
393115002537	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
393115002538	E-class dimer interface [polypeptide binding]; other site
393115002539	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
393115002540	P-class dimer interface [polypeptide binding]; other site
393115002541	active site
393115002542	Cu2+ binding site [ion binding]; other site
393115002543	Zn2+ binding site [ion binding]; other site
393115002544	Similar to Q87PL0 Conserved hypothetical protein from Vibrio parahaemolyticus (275 aa). FASTA: opt: 818 Z-score: 1003.8 E(): 4.6e-48 Smith-Waterman score: 818; 46.457 identity in 254 aa overlap. Contains a frameshift after 21 aa ORF ftt0880
393115002545	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
393115002546	Similar to last 120 amino acids of O30800 Pmi-like gene product from Methylobacterium extorquens (469 aa). FASTA: opt: 448 Z-score: 572.4 E(): 4.9e-24 Smith-Waterman score: 448; 61.111 identity in 108 aa overlap. CDS contains no start codon due to deletion at N-terminal ORF ftt0882
393115002547	deleted EC_number 1.2.1.1; Similar to CAD84818 Alcohol dehydrogenase class III from Ralstonia solanacearum (368 aa). FASTA: opt: 1760 Z-score: 1914.4 E(): 8.8e-99 Smith-Waterman score: 1760; 69.189identity in 370 aa overlap. Contains frameshifts after aa 86 and 105 ORF ftt0883
393115002548	aspartate aminotransferase; Provisional; Region: PRK07568
393115002549	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
393115002550	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115002551	homodimer interface [polypeptide binding]; other site
393115002552	catalytic residue [active]
393115002553	Cation efflux family; Region: Cation_efflux; pfam01545
393115002554	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
393115002555	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
393115002556	Walker A/P-loop; other site
393115002557	ATP binding site [chemical binding]; other site
393115002558	Q-loop/lid; other site
393115002559	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
393115002560	ABC transporter signature motif; other site
393115002561	Walker B; other site
393115002562	D-loop; other site
393115002563	H-loop/switch region; other site
393115002564	bacteriocin secretion accessory protein; Region: bacteriocin_acc; TIGR01000
393115002565	Tfp pilus assembly protein, major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilA; COG4969
393115002566	Pilin (bacterial filament); Region: Pilin; pfam00114
393115002567	Tfp pilus assembly protein, major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilA; COG4969
393115002568	Tfp pilus assembly protein, major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilA; COG4969
393115002569	Pilin (bacterial filament); Region: Pilin; pfam00114
393115002570	PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from Francisella novicida selectively dephosphorylates lipid A at the 1-position. Lipid A is the membrane-anchor component of lipopolysaccharides (LPS), the major...; Region: PAP2_lipid_A_1_phosphatase; cd03389
393115002571	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
393115002572	active site
393115002573	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14180
393115002574	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
393115002575	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
393115002576	homodimer interface [polypeptide binding]; other site
393115002577	NADP binding site [chemical binding]; other site
393115002578	substrate binding site [chemical binding]; other site
393115002579	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
393115002580	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
393115002581	dimerization interface [polypeptide binding]; other site
393115002582	putative ATP binding site [chemical binding]; other site
393115002583	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
393115002584	active site
393115002585	ATP binding site [chemical binding]; other site
393115002586	substrate binding site [chemical binding]; other site
393115002587	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
393115002588	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
393115002589	ATP-grasp domain; Region: ATP-grasp_4; cl17255
393115002590	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
393115002591	Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299
393115002592	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
393115002593	active site
393115002594	substrate binding site [chemical binding]; other site
393115002595	cosubstrate binding site; other site
393115002596	catalytic site [active]
393115002597	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
393115002598	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
393115002599	ATP-grasp domain; Region: ATP-grasp; pfam02222
393115002600	hypothetical protein; Provisional; Region: PRK14682
393115002601	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
393115002602	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
393115002603	active site
393115002604	Zn binding site [ion binding]; other site
393115002605	Mth938-like domain. The members of this family include: Mth938, 2P1, Xcr35, Rpa2829, and several uncharacterized sequences. Mth938 is a hypothetical protein encoded by the Methanobacterium thermoautotrophicum (Mth) genome. This protein crystallizes as a...; Region: Mth938-like; cd00248
393115002606	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
393115002607	O-Antigen Polymerase; Region: Wzy_C; cl04850
393115002608	DNA topoisomerase I; Validated; Region: PRK06599
393115002609	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
393115002610	active site
393115002611	interdomain interaction site; other site
393115002612	putative metal-binding site [ion binding]; other site
393115002613	nucleotide binding site [chemical binding]; other site
393115002614	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
393115002615	domain I; other site
393115002616	DNA binding groove [nucleotide binding]
393115002617	phosphate binding site [ion binding]; other site
393115002618	domain II; other site
393115002619	domain III; other site
393115002620	nucleotide binding site [chemical binding]; other site
393115002621	catalytic site [active]
393115002622	domain IV; other site
393115002623	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
393115002624	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
393115002625	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
393115002626	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
393115002627	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
393115002628	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
393115002629	P-loop; other site
393115002630	Magnesium ion binding site [ion binding]; other site
393115002631	ParB-like nuclease domain; Region: ParB; smart00470
393115002632	KorB domain; Region: KorB; pfam08535
393115002633	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
393115002634	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
393115002635	catalytic triad [active]
393115002636	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
393115002637	active site
393115002638	catalytic triad [active]
393115002639	oxyanion hole [active]
393115002640	HD domain; Region: HD_3; pfam13023
393115002641	FtsJ-like methyltransferase; Region: FtsJ; cl17430
393115002642	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
393115002643	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
393115002644	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
393115002645	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
393115002646	active site
393115002647	HIGH motif; other site
393115002648	nucleotide binding site [chemical binding]; other site
393115002649	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
393115002650	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
393115002651	active site
393115002652	KMSKS motif; other site
393115002653	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
393115002654	tRNA binding surface [nucleotide binding]; other site
393115002655	anticodon binding site; other site
393115002656	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
393115002657	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
393115002658	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
393115002659	active site
393115002660	Riboflavin kinase; Region: Flavokinase; pfam01687
393115002661	malate dehydrogenase; Provisional; Region: PRK13529
393115002662	Malic enzyme, N-terminal domain; Region: malic; pfam00390
393115002663	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
393115002664	NAD(P) binding pocket [chemical binding]; other site
393115002665	Protein of unknown function (DUF3573); Region: DUF3573; pfam12097
393115002666	Protein of unknown function (DUF3573); Region: DUF3573; pfam12097
393115002667	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115002668	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115002669	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115002670	Truncated early to prevent overlap with tRNA-val. Possible point mutation resulting in lost stop codon and run-through of sequence ORF ftt0921 hypothetical membrane protein
393115002671	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
393115002672	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
393115002673	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
393115002674	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
393115002675	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115002676	S-adenosylmethionine binding site [chemical binding]; other site
393115002677	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
393115002678	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
393115002679	putative active site [active]
393115002680	substrate binding site [chemical binding]; other site
393115002681	putative cosubstrate binding site; other site
393115002682	catalytic site [active]
393115002683	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
393115002684	substrate binding site [chemical binding]; other site
393115002685	glutathione synthetase; Provisional; Region: PRK05246
393115002686	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
393115002687	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
393115002688	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
393115002689	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
393115002690	inhibitor-cofactor binding pocket; inhibition site
393115002691	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115002692	catalytic residue [active]
393115002693	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
393115002694	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
393115002695	Similar to Q98IH5 Beta-hydroxybutyrate dehydrogenase from Rhizobium loti (256 aa). FASTA: opt: 941 Z-score: 1009.9 E(): 2.1e-48 Smith-Waterman score: 941; 55.859 identity in 256 aa overlap. Contains an in-frame stop codon after aa 60 ORF ftt0929c
393115002696	Similar to Q8XR10 Probable acetoacetate decarboxylase from Ralstonia solanacearum (247 aa). FASTA: opt: 753 Z-score: 922.8 E(): 1.5e-43 Smith-Waterman score: 753; 56.158 identity in 203 aa overlap. CDS has no start codon due to a deletion at N-terminal ORF ftt0930c
393115002697	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
393115002698	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115002699	putative substrate translocation pore; other site
393115002700	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
393115002701	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
393115002702	nucleotide binding site [chemical binding]; other site
393115002703	Similar to Q8EK84 BirA bifunctional protein from Shewanella oneidensis (319 aa). FASTA: opt: 576 Z-score: 667.4 E(): 2.5e-29 Smith-Waterman score: 576; 30.547 identity in 311 aa overlap. Contains a frameshift after aa 44 ORF ftt0933
393115002704	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
393115002705	AAA domain; Region: AAA_26; pfam13500
393115002706	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
393115002707	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
393115002708	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
393115002709	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
393115002710	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115002711	catalytic residue [active]
393115002712	biotin synthase; Region: bioB; TIGR00433
393115002713	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
393115002714	FeS/SAM binding site; other site
393115002715	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
393115002716	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
393115002717	adenosylmethionine-8-amino-7-oxononanoate transaminase; Region: bioA; TIGR00508
393115002718	inhibitor-cofactor binding pocket; inhibition site
393115002719	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115002720	catalytic residue [active]
393115002721	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
393115002722	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
393115002723	active site
393115002724	purine riboside binding site [chemical binding]; other site
393115002725	HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]; Region: PaaI; COG2050
393115002726	active site 2 [active]
393115002727	active site 1 [active]
393115002728	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
393115002729	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
393115002730	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
393115002731	catalytic center binding site [active]
393115002732	ATP binding site [chemical binding]; other site
393115002733	dihydropteroate synthase; Region: DHPS; TIGR01496
393115002734	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
393115002735	substrate binding pocket [chemical binding]; other site
393115002736	dimer interface [polypeptide binding]; other site
393115002737	inhibitor binding site; inhibition site
393115002738	Dihydroneopterin aldolase; Region: FolB; smart00905
393115002739	active site
393115002740	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
393115002741	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
393115002742	acyl-activating enzyme (AAE) consensus motif; other site
393115002743	AMP binding site [chemical binding]; other site
393115002744	active site
393115002745	CoA binding site [chemical binding]; other site
393115002746	aminodeoxychorismate synthase; Provisional; Region: PRK07508
393115002747	chorismate binding enzyme; Region: Chorismate_bind; cl10555
393115002748	Aminotransferase class IV; Region: Aminotran_4; pfam01063
393115002749	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
393115002750	substrate-cofactor binding pocket; other site
393115002751	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115002752	catalytic residue [active]
393115002753	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
393115002754	Glutamine amidotransferase class-I; Region: GATase; pfam00117
393115002755	glutamine binding [chemical binding]; other site
393115002756	catalytic triad [active]
393115002757	Similar to Q83D24 Major facilitator family transporter from Coxiella burnetii (437 aa). FASTA: opt: 293 Z-score: 313.6 bits: 67.1 E(): 1.4e-09 Smith-Waterman score: 295; 22.963 identity in 405 aa overlap. Contains a frameshift after aa 171 ORF ftt0947c
393115002758	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
393115002759	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
393115002760	active site
393115002761	catalytic tetrad [active]
393115002762	Similar to Q9KDX2 Hypothetical protein BH1089 from Bacillus halodurans (512 aa). FASTA: opt: 334 Z-score: 369.9 E(): 9.4e-13 Smith-Waterman score: 340; 26.603 identity in 421 aa overlap ORF ftt0949c
393115002763	Similar to Q9X202 Hypothetical protein TM1674 from Thermotoga maritima (237 aa). FASTA: opt: 319 Z-score: 397.2 E(): 3.1e-14 Smith-Waterman score: 319; 30.317 identity in 221 aa overlap. Contains a frameshift after aa 79 ORF ftt0950c
393115002764	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
393115002765	GTP cyclohydrolase I; Provisional; Region: PLN03044
393115002766	active site
393115002767	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
393115002768	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
393115002769	ATP binding site [chemical binding]; other site
393115002770	Mg++ binding site [ion binding]; other site
393115002771	motif III; other site
393115002772	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115002773	nucleotide binding region [chemical binding]; other site
393115002774	ATP-binding site [chemical binding]; other site
393115002775	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
393115002776	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115002777	putative substrate translocation pore; other site
393115002778	POT family; Region: PTR2; cl17359
393115002779	Uncharacterized conserved protein [Function unknown]; Region: COG0393
393115002780	glutathione reductase; Validated; Region: PRK06116
393115002781	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
393115002782	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
393115002783	2'-5' RNA ligase superfamily; Region: 2_5_RNA_ligase2; pfam13563
393115002784	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cd01983
393115002785	AAA domain; Region: AAA_18; pfam13238
393115002786	short chain dehydrogenase; Provisional; Region: PRK07577
393115002787	classical (c) SDRs; Region: SDR_c; cd05233
393115002788	NAD(P) binding site [chemical binding]; other site
393115002789	active site
393115002790	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
393115002791	putative active site [active]
393115002792	putative catalytic site [active]
393115002793	putative DNA binding site [nucleotide binding]; other site
393115002794	putative phosphate binding site [ion binding]; other site
393115002795	metal binding site A [ion binding]; metal-binding site
393115002796	putative AP binding site [nucleotide binding]; other site
393115002797	putative metal binding site B [ion binding]; other site
393115002798	Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like subfamily; subgroup includes Pseudomonas aeruginosa AotO; Region: M14_PaAOTO_like; cd06250
393115002799	active site
393115002800	Zn binding site [ion binding]; other site
393115002801	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
393115002802	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
393115002803	intracellular protease, PfpI family; Region: PfpI; TIGR01382
393115002804	potential catalytic triad [active]
393115002805	conserved cys residue [active]
393115002806	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
393115002807	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
393115002808	signal recognition particle protein; Provisional; Region: PRK10867
393115002809	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
393115002810	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
393115002811	P loop; other site
393115002812	GTP binding site [chemical binding]; other site
393115002813	Signal peptide binding domain; Region: SRP_SPB; pfam02978
393115002814	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
393115002815	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
393115002816	rRNA binding site [nucleotide binding]; other site
393115002817	predicted 30S ribosome binding site; other site
393115002818	Similar to Q8ZQE7 Putative inner membrane protein from Salmonella typhimurium (299 aa). FASTA: opt: 439 Z-score: 520.3 E(): 3.9e-21 Smith-Waterman score: 462; 28.808 identity in 302 aa overlap. Contains a frameshift after aa 128. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt0967c
393115002819	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
393115002820	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
393115002821	TrkA-N domain; Region: TrkA_N; pfam02254
393115002822	TrkA-N domain; Region: TrkA_N; pfam02254
393115002823	FeS assembly SUF system regulator, gammaproteobacterial; Region: suf_reg_Xantho; TIGR02944
393115002824	Transcriptional regulator; Region: Rrf2; pfam02082
393115002825	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
393115002826	putative ABC transporter; Region: ycf24; CHL00085
393115002827	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
393115002828	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
393115002829	Walker A/P-loop; other site
393115002830	ATP binding site [chemical binding]; other site
393115002831	Q-loop/lid; other site
393115002832	ABC transporter signature motif; other site
393115002833	Walker B; other site
393115002834	D-loop; other site
393115002835	H-loop/switch region; other site
393115002836	FeS assembly protein SufD; Region: sufD; TIGR01981
393115002837	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
393115002838	Similar to Q826R2 Hypothetical protein from Streptomyces avermitilis (289 aa). FASTA: opt: 558 Z-score: 707.3 bits: 138.7 E(): 1.7e-31 Smith-Waterman score: 558; 34.351identity in 262 aa overlap. Contains an in-frame stop codon after aa 71 ORF ftt0974
393115002839	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
393115002840	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
393115002841	catalytic residues [active]
393115002842	Transcriptional regulators [Transcription]; Region: MarR; COG1846
393115002843	Winged helix DNA-binding domain; Region: HTH_34; pfam13601
393115002844	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
393115002845	hypothetical protein; Provisional; Region: PRK07505
393115002846	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
393115002847	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115002848	catalytic residue [active]
393115002849	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
393115002850	PAS fold; Region: PAS_4; pfam08448
393115002851	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
393115002852	active site
393115002853	8-oxo-dGMP binding site [chemical binding]; other site
393115002854	nudix motif; other site
393115002855	metal binding site [ion binding]; metal-binding site
393115002856	Uncharacterized ACR, COG1678; Region: DUF179; pfam02622
393115002857	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
393115002858	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
393115002859	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
393115002860	Transglutaminase/protease-like homologues; Region: TGc; smart00460
393115002861	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
393115002862	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
393115002863	HIGH motif; other site
393115002864	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
393115002865	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
393115002866	active site
393115002867	KMSKS motif; other site
393115002868	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
393115002869	tRNA binding surface [nucleotide binding]; other site
393115002870	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
393115002871	Lipopolysaccharide-assembly; Region: LptE; cl01125
393115002872	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
393115002873	Mechanosensitive ion channel; Region: MS_channel; pfam00924
393115002874	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
393115002875	trimer interface [polypeptide binding]; other site
393115002876	active site
393115002877	cell division ATPase MinD, archaeal; Region: minD_arch; TIGR01969
393115002878	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
393115002879	Walker A motif; other site
393115002880	metabolite-proton symporter; Region: 2A0106; TIGR00883
393115002881	Similar to Q81GK4 Cardiolipin synthetase from Bacillus cereus (514 aa). FASTA: opt: 830 Z-score: 1019.9 E(): 6.5e-49 Smith-Waterman score: 830; 31.198 identity in 484 aa overlap. Contains frameshift and lacks start codon. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt0996
393115002882	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
393115002883	Putative catalytic domain, repeat 1, of uncharacterized proteins similar to bacterial cardiolipin synthase; Region: PLDc_CLS_unchar1_1; cd09156
393115002884	putative active site [active]
393115002885	catalytic site [active]
393115002886	Putative catalytic domain, repeat 2, of uncharacterized proteins similar to bacterial cardiolipin synthase; Region: PLDc_CLS_unchar1_2; cd09162
393115002887	putative active site [active]
393115002888	catalytic site [active]
393115002889	Haloacid Dehalogenase-like Hydrolases; Region: HAD_like; cl11391
393115002890	Similar to Q83BJ7 Transporter, ZIP family from Coxiella burnetii (261 aa). FASTA: opt: 365 Z-score: 455.0 E(): 1.9e-17 Smith-Waterman score: 365; 32.593 identity in 270 aa overlap. Contains a frameshfit after aa 73 ORF ftt0999c
393115002891	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
393115002892	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
393115002893	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
393115002894	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
393115002895	metal binding site 2 [ion binding]; metal-binding site
393115002896	putative DNA binding helix; other site
393115002897	metal binding site 1 [ion binding]; metal-binding site
393115002898	dimer interface [polypeptide binding]; other site
393115002899	structural Zn2+ binding site [ion binding]; other site
393115002900	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
393115002901	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
393115002902	putative tRNA-binding site [nucleotide binding]; other site
393115002903	B3/4 domain; Region: B3_4; pfam03483
393115002904	tRNA synthetase B5 domain; Region: B5; smart00874
393115002905	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
393115002906	dimer interface [polypeptide binding]; other site
393115002907	motif 1; other site
393115002908	motif 3; other site
393115002909	motif 2; other site
393115002910	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; smart00896
393115002911	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
393115002912	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
393115002913	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
393115002914	dimer interface [polypeptide binding]; other site
393115002915	motif 1; other site
393115002916	active site
393115002917	motif 2; other site
393115002918	motif 3; other site
393115002919	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
393115002920	EamA-like transporter family; Region: EamA; pfam00892
393115002921	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
393115002922	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115002923	MFS/sugar transport protein; Region: MFS_2; pfam13347
393115002924	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
393115002925	Aspartyl protease; Region: Asp_protease_2; pfam13650
393115002926	inhibitor binding site; inhibition site
393115002927	catalytic motif [active]
393115002928	Catalytic residue [active]
393115002929	Protein of unknown function (DUF2975); Region: DUF2975; pfam11188
393115002930	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
393115002931	non-specific DNA binding site [nucleotide binding]; other site
393115002932	salt bridge; other site
393115002933	sequence-specific DNA binding site [nucleotide binding]; other site
393115002934	Protein of unknown function (DUF2975); Region: DUF2975; pfam11188
393115002935	Similar to Q8EEM6 Bax protein,putative (255 aa). FASTA: opt: 393 Z-score: 458.7 E(): 1.1e-17 Smith-Waterman score: 393; 34.906 identity in 212 aa overlap. Contains a frameshift after aa 53. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1012
393115002936	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
393115002937	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115002938	Walker A motif; other site
393115002939	ATP binding site [chemical binding]; other site
393115002940	Walker B motif; other site
393115002941	arginine finger; other site
393115002942	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
393115002943	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
393115002944	classical (c) SDRs; Region: SDR_c; cd05233
393115002945	NAD(P) binding site [chemical binding]; other site
393115002946	active site
393115002947	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
393115002948	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
393115002949	active site
393115002950	catalytic triad [active]
393115002951	oxyanion hole [active]
393115002952	switch loop; other site
393115002953	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
393115002954	putative active site pocket [active]
393115002955	dimerization interface [polypeptide binding]; other site
393115002956	putative catalytic residue [active]
393115002957	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
393115002958	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
393115002959	TPP-binding site; other site
393115002960	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
393115002961	PYR/PP interface [polypeptide binding]; other site
393115002962	dimer interface [polypeptide binding]; other site
393115002963	TPP binding site [chemical binding]; other site
393115002964	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
393115002965	GMP synthase; Reviewed; Region: guaA; PRK00074
393115002966	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
393115002967	AMP/PPi binding site [chemical binding]; other site
393115002968	candidate oxyanion hole; other site
393115002969	catalytic triad [active]
393115002970	potential glutamine specificity residues [chemical binding]; other site
393115002971	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
393115002972	ATP Binding subdomain [chemical binding]; other site
393115002973	Ligand Binding sites [chemical binding]; other site
393115002974	Dimerization subdomain; other site
393115002975	amino acid transporter; Region: 2A0306; TIGR00909
393115002976	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
393115002977	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
393115002978	dimerization interface 3.5A [polypeptide binding]; other site
393115002979	active site
393115002980	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
393115002981	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
393115002982	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
393115002983	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
393115002984	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
393115002985	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
393115002986	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
393115002987	Walker A/P-loop; other site
393115002988	ATP binding site [chemical binding]; other site
393115002989	Q-loop/lid; other site
393115002990	ABC transporter signature motif; other site
393115002991	Walker B; other site
393115002992	D-loop; other site
393115002993	H-loop/switch region; other site
393115002994	OstA-like protein; Region: OstA; cl00844
393115002995	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
393115002996	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
393115002997	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
393115002998	active site
393115002999	motif I; other site
393115003000	motif II; other site
393115003001	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
393115003002	dimer interface [polypeptide binding]; other site
393115003003	substrate binding site [chemical binding]; other site
393115003004	metal binding sites [ion binding]; metal-binding site
393115003005	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
393115003006	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
393115003007	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
393115003008	Protein of unknown function (DUF493); Region: DUF493; pfam04359
393115003009	lipoate-protein ligase B; Provisional; Region: PRK14342
393115003010	Similar to Q8FKS3 Putative oligogalacturonide transporter from Escherichia coli O6 (504 aa). FASTA: opt: 724 Z-score: 813.6 E(): 2e-37 Smith-Waterman score: 763; 30.675 identity in 489 aa overlap. Contains as in-frame stop codon ORF ftt1032
393115003011	Similar to Q8ZKT9 Putative alpha-xylosidase from Salmonella typhimurium (678 aa). FASTA: opt: 2551 Z-score: 3058.2 E(): 1.9e-162 Smith-Waterman score: 2551; 54.364 identity in 653 aa overlap. Contains an in-frame stop codon
393115003012	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
393115003013	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
393115003014	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
393115003015	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
393115003016	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
393115003017	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
393115003018	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
393115003019	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
393115003020	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
393115003021	DNA binding residues [nucleotide binding]
393115003022	CHC2 zinc finger; Region: zf-CHC2; pfam01807
393115003023	DNA primase; Validated; Region: dnaG; PRK05667
393115003024	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
393115003025	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
393115003026	active site
393115003027	metal binding site [ion binding]; metal-binding site
393115003028	interdomain interaction site; other site
393115003029	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
393115003030	Yqey-like protein; Region: YqeY; pfam09424
393115003031	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
393115003032	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
393115003033	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
393115003034	N-acetyl-D-glucosamine binding site [chemical binding]; other site
393115003035	catalytic residue [active]
393115003036	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
393115003037	active site
393115003038	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
393115003039	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
393115003040	Ligand Binding Site [chemical binding]; other site
393115003041	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
393115003042	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
393115003043	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
393115003044	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
393115003045	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
393115003046	substrate binding pocket [chemical binding]; other site
393115003047	chain length determination region; other site
393115003048	substrate-Mg2+ binding site; other site
393115003049	catalytic residues [active]
393115003050	aspartate-rich region 1; other site
393115003051	active site lid residues [active]
393115003052	aspartate-rich region 2; other site
393115003053	PQ loop repeat; Region: PQ-loop; cl17546
393115003054	Similar to CYSC_CLOAB (Q97MT8) Adenylylsulfate kinase from Clostridium acetobutylicum (200 aa). FASTA: opt: 732 Z-score: 905.0 E(): 1.6e-42 Smith-Waterman score: 732; 59.669 identity in 181 aa overlap. Some homologs have cysN and cysC concatenated (cysNC). No start codon due to deletion at N-terminal
393115003055	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
393115003056	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
393115003057	CysD dimerization site [polypeptide binding]; other site
393115003058	G1 box; other site
393115003059	putative GEF interaction site [polypeptide binding]; other site
393115003060	GTP/Mg2+ binding site [chemical binding]; other site
393115003061	Switch I region; other site
393115003062	G2 box; other site
393115003063	G3 box; other site
393115003064	Switch II region; other site
393115003065	G4 box; other site
393115003066	G5 box; other site
393115003067	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
393115003068	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
393115003069	Similar to Q9ZIX7, putative transposase from Haemophilus gallinarum (216 aa). FASTA: opt: 566 Z-score: 710.4 E(): 1e-31 Smith-Waterman score: 566; 42.056 identity in 214 aa overlap. Stop codon at aa position 99 Identical to FTF1792c. However, there is a mutation in the IRR of this copy that abolishes the stop codon that is present in FTF1792c. This generates a hypothetical protein of an extra 5 aa in this instance. ORF ftt1053c
393115003070	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
393115003071	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
393115003072	preprotein translocase subunit SecA; Validated; Region: secA; CHL00122
393115003073	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
393115003074	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
393115003075	RNA binding surface [nucleotide binding]; other site
393115003076	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
393115003077	probable active site [active]
393115003078	Tetratricopeptide repeat; Region: TPR_12; pfam13424
393115003079	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
393115003080	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
393115003081	FeS/SAM binding site; other site
393115003082	replicative DNA helicase; Region: DnaB; TIGR00665
393115003083	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
393115003084	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
393115003085	Walker A motif; other site
393115003086	ATP binding site [chemical binding]; other site
393115003087	Walker B motif; other site
393115003088	DNA binding loops [nucleotide binding]
393115003089	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
393115003090	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
393115003091	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
393115003092	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
393115003093	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
393115003094	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
393115003095	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
393115003096	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
393115003097	catalytic core [active]
393115003098	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115003099	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115003100	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115003101	Similar to Q8RG91 Type III restriction-modification system restriction subunit from Fusobacterium nucleatum (subsp. nucleatum) (997 aa). FASTA: opt: 2647 Z-score: 2741.6 E(): 7.4e-145 Smith-Waterman score: 2729; 46.356 identity in 1029 aa overlap.
393115003102	Abi-like protein; Region: Abi_2; cl01988
393115003103	Domain of unknown function (DUF4391); Region: DUF4391; pfam14335
393115003104	Similar to EAA25085 ATP-dependent helicase HEPA from Fusobacterium nucleatum subsp. vincentii ATCC 49256 (1070 aa). FASTA: opt: 3128 Z-score: 3170.3 E(): 9.7e-169 Smith-Waterman score: 3128; 50.250 identity in 1001 aa overlap. Contains a frameshift after aa 974. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1070c
393115003105	Antirestriction protein (ArdA); Region: ArdA; pfam07275
393115003106	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115003107	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115003108	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115003109	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
393115003110	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
393115003111	non-specific DNA binding site [nucleotide binding]; other site
393115003112	salt bridge; other site
393115003113	sequence-specific DNA binding site [nucleotide binding]; other site
393115003114	HipA N-terminal domain; Region: couple_hipA; TIGR03071
393115003115	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
393115003116	HipA-like N-terminal domain; Region: HipA_N; pfam07805
393115003117	HipA-like C-terminal domain; Region: HipA_C; pfam07804
393115003118	recombination associated protein; Reviewed; Region: rdgC; PRK00321
393115003119	Predicted sulfurtransferase [General function prediction only]; Region: COG1054
393115003120	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
393115003121	active site residue [active]
393115003122	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
393115003123	S1 domain; Region: S1_2; pfam13509
393115003124	ATP-dependent DNA helicase Rep; Region: rep; TIGR01074
393115003125	Part of AAA domain; Region: AAA_19; pfam13245
393115003126	AAA domain; Region: AAA_14; pfam13173
393115003127	Family description; Region: UvrD_C_2; pfam13538
393115003128	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
393115003129	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
393115003130	Isochorismatase family; Region: Isochorismatase; pfam00857
393115003131	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
393115003132	catalytic triad [active]
393115003133	conserved cis-peptide bond; other site
393115003134	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
393115003135	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
393115003136	Isochorismatase family; Region: Isochorismatase; pfam00857
393115003137	catalytic triad [active]
393115003138	conserved cis-peptide bond; other site
393115003139	transaldolase-like protein; Provisional; Region: PTZ00411
393115003140	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
393115003141	active site
393115003142	dimer interface [polypeptide binding]; other site
393115003143	catalytic residue [active]
393115003144	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
393115003145	Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260
393115003146	interface (dimer of trimers) [polypeptide binding]; other site
393115003147	Substrate-binding/catalytic site; other site
393115003148	Zn-binding sites [ion binding]; other site
393115003149	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
393115003150	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
393115003151	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
393115003152	motif 1; other site
393115003153	active site
393115003154	motif 2; other site
393115003155	motif 3; other site
393115003156	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
393115003157	Similar to REP_BUCAI (P57654) ATP-dependent DNA helicase rep from Buchnera aphidicola (subsp. Acyrthosiphon pisum) (Acyrthosiphon pisum symbiotic bacterium) (645 aa). FASTA: opt: 662 Z-score: 713.3 bits: 142.3 E(): 7.7e-32 Smith-Waterman score: 662; 28.502 identity in 621 aa overlap. Contains a frameshift after aa 167. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift. ORF ftt1098c
393115003158	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
393115003159	Similar to YJES_ECOLI (P39288) Putative electron transport protein from Escherichia coli (379 aa). FASTA: opt: 611 Z-score: 746.8 E(): 1e-33 Smith-Waterman score: 999; 45.938 identity in 357 aa overlap. Contains 2 frameshifts after aa 119 and 176. Both frameshifts occur at heptanucleotide sequences and so could be part of a programmed translational frameshifts
393115003160	Similar to O32828 Macrophage infectivity potentiator from Legionella oakridgensis (234 aa). FASTA: opt: 191 Z-score: 250.2 E(): 4.8e-06 Smith-Waterman score: 191; 35.484identity in 93 aa overlap. Deletion at carboxy terminal truncates this protein ORF ftt1102
393115003161	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
393115003162	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
393115003163	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
393115003164	catalytic residues [active]
393115003165	Similar to Q9CKS3 Bcr from Pasteurella multocida (399 aa). FASTA: opt: 568 Z-score: 616.5 E(): 1.9e-26 Smith-Waterman score: 568; 30.518 identity in 367 aa overlap. Contains a frameshift after aa 85 Putative drug transport protein.
393115003166	bifunctional methionine sulfoxide reductase B/A protein; Provisional; Region: PRK05550
393115003167	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
393115003168	Peptide methionine sulfoxide reductase; Region: PMSR; pfam01625
393115003169	TspO/MBR family; Region: TspO_MBR; pfam03073
393115003170	Similar to Q8L2B3 (Q8L2B3) Choline transporter from Proteus vulgaris (665 aa). FASTA: opt: 1958 Z-score: 2178.1 E(): 2e-113 Smith-Waterman score: 2111; 47.546 identity in 652 aa overlap. Contains a frameshift after aa 133. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift
393115003171	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
393115003172	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
393115003173	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
393115003174	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
393115003175	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
393115003176	active site
393115003177	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
393115003178	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115003179	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
393115003180	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
393115003181	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
393115003182	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
393115003183	DNA binding residues [nucleotide binding]
393115003184	Src Homology 3 domain superfamily; Region: SH3; cl17036
393115003185	peptide ligand binding site [polypeptide binding]; other site
393115003186	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
393115003187	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
393115003188	Protein export membrane protein; Region: SecD_SecF; pfam02355
393115003189	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
393115003190	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
393115003191	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
393115003192	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
393115003193	Isochorismatase family; Region: Isochorismatase; pfam00857
393115003194	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
393115003195	catalytic triad [active]
393115003196	conserved cis-peptide bond; other site
393115003197	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
393115003198	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
393115003199	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
393115003200	dimerization interface [polypeptide binding]; other site
393115003201	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
393115003202	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
393115003203	Similar to Q9JTA5 Insertion element IS1016 transposase (fragment) from Neisseria meningitidis (serogroup A) (151 aa). FASTA: opt: 364 Z-score: 568.7 E(): 8.7e-24 Smith-Waterman score: 364; 77.778identity in 72 aa overlap. FTF1121 is a fragment of FTF1583. ORF ftt1121
393115003204	Protein of unknown function (DUF3281); Region: DUF3281; pfam11685
393115003205	Protein of unknown function (DUF3281); Region: DUF3281; pfam11685
393115003206	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
393115003207	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
393115003208	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
393115003209	Walker A/P-loop; other site
393115003210	ATP binding site [chemical binding]; other site
393115003211	Q-loop/lid; other site
393115003212	ABC transporter signature motif; other site
393115003213	Walker B; other site
393115003214	D-loop; other site
393115003215	H-loop/switch region; other site
393115003216	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
393115003217	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
393115003218	dimer interface [polypeptide binding]; other site
393115003219	conserved gate region; other site
393115003220	ABC-ATPase subunit interface; other site
393115003221	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
393115003222	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
393115003223	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
393115003224	aromatic amino acid transport protein; Region: araaP; TIGR00837
393115003225	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
393115003226	active site residue [active]
393115003227	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
393115003228	active site residue [active]
393115003229	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
393115003230	homotrimer interaction site [polypeptide binding]; other site
393115003231	zinc binding site [ion binding]; other site
393115003232	CDP-binding sites; other site
393115003233	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115003234	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
393115003235	cyanophycin synthetase; Provisional; Region: PRK14016
393115003236	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
393115003237	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
393115003238	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
393115003239	Similar to Q97D94 Competence-damage inducible protein, CINA, from Clostridium acetobutylicum (411 aa). FASTA: opt: 398 Z-score: 508.8 E(): 1.9e-20 Smith-Waterman score: 398; 31.687 identity in 243 aa overlap. Appears to be a deletion at carboxy terminus ORF ftt1131
393115003240	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
393115003241	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
393115003242	active site
393115003243	catalytic site [active]
393115003244	type IV-A pilus assembly ATPase PilB; Region: type_IV_pilB; TIGR02538
393115003245	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
393115003246	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
393115003247	Walker A motif; other site
393115003248	ATP binding site [chemical binding]; other site
393115003249	Walker B motif; other site
393115003250	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
393115003251	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
393115003252	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
393115003253	Similar to Q8EAU9 Conserved hypothetical protein from Shewanella oneidensis (390 aa). FASTA: opt: 1502 Z-score: 1709.5 E(): 2.3e-87 Smith-Waterman score: 1502; 57.584 identity in 389 aa overlap. Contains two frameshifts after aa 20 and 291. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1135c
393115003254	ferrochelatase; Reviewed; Region: hemH; PRK00035
393115003255	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
393115003256	C-terminal domain interface [polypeptide binding]; other site
393115003257	active site
393115003258	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
393115003259	active site
393115003260	N-terminal domain interface [polypeptide binding]; other site
393115003261	Similar to Q83CE4 Deoxyribodipyrimidine photolyase-class I from Coxiella burnetii (472 aa). FASTA: opt: 1369 Z-score: 1649.6 E(): 5.4e-84 Smith-Waterman score: 1369; 43.103identity in 464 aa overlap. Contains a frameshift after aa 86
393115003262	Similar to Q8PW11 Hypothetical protein MM1793 from Methanosarcina mazei (Methanosarcina frisia) (135 aa). FASTA: opt: 328 Z-score: 442.8 E(): 9e-17 Smith-Waterman score: 328; 50.000 identity in 96 aa overlap. CDS interrupted by an ISFtu1 element ORF ftt1141
393115003263	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115003264	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115003265	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115003266	Similar to Q9RYF4 Oxidoreductase, short-chain dehydrogenase family from Deinococcus radiodurans (390 aa). FASTA: opt: 913 Z-score: 1084.4 E(): 1.6e-52 Smith-Waterman score: 913; 50.360 identity in 278 aa overlap. Contains a frameshift after aa 153. ameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1144
393115003267	Putative cation transport regulator [General function prediction only]; Region: ChaB; COG4572
393115003268	Similar to EAA24361 (EAA24361) Aldose 1-epimerase (EC 5.1.3.3) from Fusobacterium nucleatum subsp. vincentii ATCC 49256 (330 aa). FASTA: opt: 574 Z-score: 714.1 E(): 6.9e-32 Smith-Waterman score: 574; 34.783 identity in 322 aa overlap. Contains a frameshift after aa 231, possibly caused by an internal deletion
393115003269	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
393115003270	Flavoprotein; Region: Flavoprotein; pfam02441
393115003271	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
393115003272	benzoate transport; Region: 2A0115; TIGR00895
393115003273	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003274	putative substrate translocation pore; other site
393115003275	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
393115003276	bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: PRK11904
393115003277	Proline dehydrogenase; Region: Pro_dh; pfam01619
393115003278	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
393115003279	Glutamate binding site [chemical binding]; other site
393115003280	NAD binding site [chemical binding]; other site
393115003281	catalytic residues [active]
393115003282	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
393115003283	NAD(P) binding site [chemical binding]; other site
393115003284	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
393115003285	Flavinator of succinate dehydrogenase; Region: Sdh5; pfam03937
393115003286	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
393115003287	active site
393115003288	dimer interface [polypeptide binding]; other site
393115003289	metal binding site [ion binding]; metal-binding site
393115003290	shikimate kinase; Reviewed; Region: aroK; PRK00131
393115003291	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
393115003292	ADP binding site [chemical binding]; other site
393115003293	magnesium binding site [ion binding]; other site
393115003294	putative shikimate binding site; other site
393115003295	type IV pilus secretin (or competence protein) PilQ; Region: IV_pilus_PilQ; TIGR02515
393115003296	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
393115003297	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
393115003298	Pilus assembly protein, PilP; Region: PilP; pfam04351
393115003299	Pilus assembly protein, PilO; Region: PilO; cl01234
393115003300	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
393115003301	adenylate kinase; Reviewed; Region: adk; PRK00279
393115003302	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
393115003303	AMP-binding site [chemical binding]; other site
393115003304	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
393115003305	Similar to Q88DT2 D-lactate dehydrogenase, putative from Pseudomonas putida (strain KT2440) (936 aa). FASTA: opt: 1665 Z-score: 1856.9 E(): 1.5e-95 Smith-Waterman score: 2125; 37.763identity in 903 aa overlap. Contains an in-frame stop codon after aa 312 and a frameshift after aa 431 ORF ftt1162c
393115003306	GTPase Era; Reviewed; Region: era; PRK00089
393115003307	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
393115003308	G1 box; other site
393115003309	GTP/Mg2+ binding site [chemical binding]; other site
393115003310	Switch I region; other site
393115003311	G2 box; other site
393115003312	Switch II region; other site
393115003313	G3 box; other site
393115003314	G4 box; other site
393115003315	G5 box; other site
393115003316	aspartate aminotransferase; Provisional; Region: PRK05764
393115003317	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
393115003318	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115003319	homodimer interface [polypeptide binding]; other site
393115003320	catalytic residue [active]
393115003321	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
393115003322	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
393115003323	putative active site [active]
393115003324	putative dimer interface [polypeptide binding]; other site
393115003325	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
393115003326	Glycoprotease family; Region: Peptidase_M22; pfam00814
393115003327	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
393115003328	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
393115003329	active site
393115003330	dimer interface [polypeptide binding]; other site
393115003331	ribosome biogenesis GTP-binding protein YlqF; Region: GTPase_YlqF; TIGR03596
393115003332	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
393115003333	GTP/Mg2+ binding site [chemical binding]; other site
393115003334	G4 box; other site
393115003335	G5 box; other site
393115003336	G1 box; other site
393115003337	Switch I region; other site
393115003338	G2 box; other site
393115003339	G3 box; other site
393115003340	Switch II region; other site
393115003341	Sel1 repeat; Region: Sel1; cl02723
393115003342	HsdM N-terminal domain; Region: HsdM_N; pfam12161
393115003343	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
393115003344	Methyltransferase domain; Region: Methyltransf_26; pfam13659
393115003345	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
393115003346	DNA-binding site [nucleotide binding]; DNA binding site
393115003347	RNA-binding motif; other site
393115003348	Similar to CAD76983 Type I restriction enzyme EcoEI specificity protein from Rhodopirellula baltica (550 aa). FASTA: opt: 492 Z-score: 583.4 E(): 1.3e-24 Smith-Waterman score: 492; 42.929 identity in 198 aa overlap. Contains an in-frame stop codon at aa 48 and a frameshift at aa 133
393115003349	Similar to Q8RIX1 HsdR from Campylobacter jejuni (769 aa). FASTA: opt: 2132 Z-score: 2421.3 E(): 5.6e-127 Smith-Waterman score: 2642; 53.402 identity in 779 aa overlap. Contains a frameshift after aa 61 and an in-frame stop codon after aa 208
393115003350	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
393115003351	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
393115003352	G1 box; other site
393115003353	putative GEF interaction site [polypeptide binding]; other site
393115003354	GTP/Mg2+ binding site [chemical binding]; other site
393115003355	Switch I region; other site
393115003356	G2 box; other site
393115003357	G3 box; other site
393115003358	Switch II region; other site
393115003359	G4 box; other site
393115003360	G5 box; other site
393115003361	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
393115003362	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
393115003363	Similar to Q8EXW1 Conserved hypothetical protein from Leptospira interrogans (250 aa). FASTA: opt: 528 Z-score: 655.2 E(): 1.3e-28 Smith-Waterman score: 528; 34.711 identity in 242 aa overlap. Contains an in-frame stop codon after aa 107 ORF ftt1180
393115003364	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
393115003365	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
393115003366	Similar to Q9Z674 Lipoprotein from Zymomonas mobilis (256 aa). FASTA: opt: 348 Z-score: 428.0 E(): 6e-16 Smith-Waterman score: 348; 33.333 identity in 234 aa overlap. Contains an in-frame stop codon
393115003367	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
393115003368	tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain; Region: MnmC_Cterm; TIGR03197
393115003369	hypothetical protein; Validated; Region: PRK01777
393115003370	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
393115003371	putative coenzyme Q binding site [chemical binding]; other site
393115003372	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
393115003373	SmpB-tmRNA interface; other site
393115003374	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
393115003375	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
393115003376	Ligand Binding Site [chemical binding]; other site
393115003377	Similar to Q87YJ5 Major facilitator family transporter from Pseudomonas syringae (pv. tomato) (445 aa). FASTA: opt: 858 Z-score: 886.6 E(): 1.7e-41 Smith-Waterman score: 858; 34.123 identity in 422 aa overlap. Contains 2 frameshifts after aa 150 and 196 ORF ftt1189c
393115003378	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
393115003379	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
393115003380	generic binding surface II; other site
393115003381	generic binding surface I; other site
393115003382	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
393115003383	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
393115003384	metal binding site [ion binding]; metal-binding site
393115003385	dimer interface [polypeptide binding]; other site
393115003386	Similar to Q9RSX6 Hypothetical protein DR1993 from Deinococcus radiodurans (274 aa). FASTA: opt: 488 Z-score: 621.6 E(): 9.8e-27 Smith-Waterman score: 488; 32.500 identity in 280 aa overlap. Contains a frameshfit after aa 295 ORF ftt1192c
393115003387	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
393115003388	putative dimer interface [polypeptide binding]; other site
393115003389	putative active site [active]
393115003390	A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168
393115003391	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307
393115003392	Similar to Q88JG1 Conserved hypothetical protein from Pseudomonas putida (strain KT2440) (469 aa). FASTA: opt: 1631 Z-score: 1944.7 E(): 2e-100 Smith-Waterman score: 1631; 52.903 identity in 465 aa overlap. Contains a frameshift at aa 59. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1195c
393115003393	metabolite-proton symporter; Region: 2A0106; TIGR00883
393115003394	glutamate racemase; Provisional; Region: PRK00865
393115003395	Nuclease-related domain; Region: NERD; pfam08378
393115003396	excinuclease ABC subunit B; Provisional; Region: PRK05298
393115003397	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
393115003398	ATP binding site [chemical binding]; other site
393115003399	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115003400	nucleotide binding region [chemical binding]; other site
393115003401	ATP-binding site [chemical binding]; other site
393115003402	Ultra-violet resistance protein B; Region: UvrB; pfam12344
393115003403	UvrB/uvrC motif; Region: UVR; pfam02151
393115003404	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
393115003405	active site
393115003406	catalytic site [active]
393115003407	substrate binding site [chemical binding]; other site
393115003408	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
393115003409	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
393115003410	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115003411	NAD(P) binding site [chemical binding]; other site
393115003412	active site
393115003413	Transcriptional regulator [Transcription]; Region: LysR; COG0583
393115003414	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
393115003415	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
393115003416	putative effector binding pocket; other site
393115003417	dimerization interface [polypeptide binding]; other site
393115003418	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
393115003419	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
393115003420	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
393115003421	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
393115003422	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
393115003423	tetramer (dimer of dimers) interface [polypeptide binding]; other site
393115003424	active site
393115003425	dimer interface [polypeptide binding]; other site
393115003426	Similar to Q8EAQ3 Peptidase, M13 family from Shewanella oneidensis (694 aa). FASTA: opt: 1942 Z-score: 2116.8 E(): 4.7e-110 Smith-Waterman score: 1942; 44.688 identity in 640 aa overlap. This CDS lacks a start codon due to an interruption of an ISFtu1 element at the N-terminal end ORF ftt1209c
393115003427	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115003428	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115003429	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115003430	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
393115003431	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
393115003432	dimer interface [polypeptide binding]; other site
393115003433	active site
393115003434	metal binding site [ion binding]; metal-binding site
393115003435	glutathione binding site [chemical binding]; other site
393115003436	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; cl00756
393115003437	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
393115003438	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
393115003439	active site
393115003440	motif I; other site
393115003441	motif II; other site
393115003442	Soluble P-type ATPase [General function prediction only]; Region: COG4087
393115003443	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
393115003444	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
393115003445	ABC-type uncharacterized transport system, duplicated ATPase component [General function prediction only]; Region: COG4172
393115003446	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
393115003447	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
393115003448	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
393115003449	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
393115003450	Uncharacterized protein family (UPF0149); Region: UPF0149; cl01173
393115003451	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
393115003452	BolA-like protein; Region: BolA; cl00386
393115003453	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
393115003454	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
393115003455	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
393115003456	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
393115003457	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
393115003458	Recombination protein O N terminal; Region: RecO_N; pfam11967
393115003459	Recombination protein O C terminal; Region: RecO_C; pfam02565
393115003460	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
393115003461	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
393115003462	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
393115003463	catalytic residue [active]
393115003464	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
393115003465	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
393115003466	homodimer interface [polypeptide binding]; other site
393115003467	oligonucleotide binding site [chemical binding]; other site
393115003468	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
393115003469	thymidylate synthase; Reviewed; Region: thyA; PRK01827
393115003470	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
393115003471	dimerization interface [polypeptide binding]; other site
393115003472	active site
393115003473	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
393115003474	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
393115003475	ligand binding site [chemical binding]; other site
393115003476	NAD binding site [chemical binding]; other site
393115003477	tetramer interface [polypeptide binding]; other site
393115003478	catalytic site [active]
393115003479	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
393115003480	L-serine binding site [chemical binding]; other site
393115003481	ACT domain interface; other site
393115003482	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
393115003483	Ligand Binding Site [chemical binding]; other site
393115003484	TilS substrate C-terminal domain; Region: TilS_C; smart00977
393115003485	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115003486	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115003487	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115003488	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003489	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115003490	putative substrate translocation pore; other site
393115003491	POT family; Region: PTR2; cl17359
393115003492	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
393115003493	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
393115003494	active site
393115003495	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
393115003496	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
393115003497	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
393115003498	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
393115003499	Ligand binding site; other site
393115003500	metal-binding site
393115003501	hypothetical protein; Provisional; Region: PRK05255
393115003502	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
393115003503	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
393115003504	dimer interface [polypeptide binding]; other site
393115003505	active site
393115003506	glycine-pyridoxal phosphate binding site [chemical binding]; other site
393115003507	folate binding site [chemical binding]; other site
393115003508	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
393115003509	FAD binding domain; Region: FAD_binding_4; pfam01565
393115003510	Berberine and berberine like; Region: BBE; pfam08031
393115003511	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
393115003512	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
393115003513	TPR motif; other site
393115003514	binding surface
393115003515	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
393115003516	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
393115003517	RNA binding surface [nucleotide binding]; other site
393115003518	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
393115003519	active site
393115003520	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
393115003521	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
393115003522	Permease; Region: Permease; pfam02405
393115003523	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
393115003524	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
393115003525	Walker A/P-loop; other site
393115003526	ATP binding site [chemical binding]; other site
393115003527	Q-loop/lid; other site
393115003528	ABC transporter signature motif; other site
393115003529	Walker B; other site
393115003530	D-loop; other site
393115003531	H-loop/switch region; other site
393115003532	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
393115003533	mce related protein; Region: MCE; pfam02470
393115003534	Protein of unknown function (DUF445); Region: DUF445; pfam04286
393115003535	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
393115003536	RNA methyltransferase, RsmE family; Region: TIGR00046
393115003537	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
393115003538	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003539	putative substrate translocation pore; other site
393115003540	POT family; Region: PTR2; cl17359
393115003541	Long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07059
393115003542	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
393115003543	acyl-activating enzyme (AAE) consensus motif; other site
393115003544	putative AMP binding site [chemical binding]; other site
393115003545	putative active site [active]
393115003546	putative CoA binding site [chemical binding]; other site
393115003547	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
393115003548	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
393115003549	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
393115003550	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003551	putative substrate translocation pore; other site
393115003552	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
393115003553	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
393115003554	HlyD family secretion protein; Region: HlyD_3; pfam13437
393115003555	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
393115003556	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
393115003557	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
393115003558	homodimer interface [polypeptide binding]; other site
393115003559	NAD binding pocket [chemical binding]; other site
393115003560	ATP binding pocket [chemical binding]; other site
393115003561	Mg binding site [ion binding]; other site
393115003562	active-site loop [active]
393115003563	Similar to Q8Y1Q6 Putative TRP repressor binding protein homolog from Ralstonia solanacearum (Pseudomonas solanacearum) (190 aa). FASTA: opt: 526 Z-score: 661.0 E(): 6.3e-29 Smith-Waterman score: 526; 45.503 identity in 189 aa overlap. Contains 2 frameshifts after aa 47 and 85 ORF ftt1261c
393115003564	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115003565	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115003566	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115003567	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
393115003568	ISFtu2, fragment. Transposase, member of the IS5 family. Identical to Q8GM03 putative transposase from Francisella tularensis (247 aa) in 154aa overlap. ISFtu2 ORF Caboxy terminal only
393115003569	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115003570	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115003571	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115003572	Pirin-related protein [General function prediction only]; Region: COG1741
393115003573	Pirin; Region: Pirin; pfam02678
393115003574	Transcriptional regulator [Transcription]; Region: LysR; COG0583
393115003575	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
393115003576	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
393115003577	putative effector binding pocket; other site
393115003578	dimerization interface [polypeptide binding]; other site
393115003579	chaperone protein DnaJ; Provisional; Region: PRK10767
393115003580	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
393115003581	HSP70 interaction site [polypeptide binding]; other site
393115003582	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
393115003583	substrate binding site [polypeptide binding]; other site
393115003584	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
393115003585	Zn binding sites [ion binding]; other site
393115003586	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
393115003587	dimer interface [polypeptide binding]; other site
393115003588	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
393115003589	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
393115003590	nucleotide binding site [chemical binding]; other site
393115003591	GrpE; Region: GrpE; pfam01025
393115003592	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
393115003593	dimer interface [polypeptide binding]; other site
393115003594	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
393115003595	Membrane-bound lytic murein transglycosylase [Cell envelope biogenesis, outer membrane]; Region: MltA; COG2821
393115003596	MltA specific insert domain; Region: MltA; smart00925
393115003597	3D domain; Region: 3D; pfam06725
393115003598	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
393115003599	Protoporphyrinogen oxidase [Coenzyme metabolism]; Region: HemY; COG1232
393115003600	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
393115003601	23S rRNA interface [nucleotide binding]; other site
393115003602	L3 interface [polypeptide binding]; other site
393115003603	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
393115003604	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
393115003605	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
393115003606	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
393115003607	Na binding site [ion binding]; other site
393115003608	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
393115003609	RNA/DNA hybrid binding site [nucleotide binding]; other site
393115003610	active site
393115003611	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
393115003612	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
393115003613	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
393115003614	active site
393115003615	phosphorylation site [posttranslational modification]
393115003616	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
393115003617	30S subunit binding site; other site
393115003618	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
393115003619	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
393115003620	trmE is a tRNA modification GTPase; Region: trmE; cd04164
393115003621	G1 box; other site
393115003622	GTP/Mg2+ binding site [chemical binding]; other site
393115003623	Switch I region; other site
393115003624	G2 box; other site
393115003625	Switch II region; other site
393115003626	G3 box; other site
393115003627	G4 box; other site
393115003628	G5 box; other site
393115003629	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
393115003630	Transcriptional regulator [Transcription]; Region: LysR; COG0583
393115003631	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
393115003632	putative DNA binding site [nucleotide binding]; other site
393115003633	putative Zn2+ binding site [ion binding]; other site
393115003634	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
393115003635	dimerization interface [polypeptide binding]; other site
393115003636	Similar to Q8A8A8 Choloylglycine hydrolase from Bacteroides thetaiotaomicron (326 aa). FASTA: opt: 588 Z-score: 716.9 E(): 4.8e-32 Smith-Waterman score: 588; 34.700 identity in 317 aa overlap. Contains an in-frame stop codon at aa 258 ORF ftt1286
393115003637	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
393115003638	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
393115003639	dimer interface [polypeptide binding]; other site
393115003640	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115003641	catalytic residue [active]
393115003642	Similar to Q9KQ90 Hypothetical protein VC2111 from Vibrio cholerae (175 aa). FASTA: opt: 309 Z-score: 410.6 E(): 5.6e-15 Smith-Waterman score: 309; 41.912 identity in 136 aa overlap. ORF ftt1289
393115003643	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
393115003644	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
393115003645	active site
393115003646	HIGH motif; other site
393115003647	KMSKS motif; other site
393115003648	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
393115003649	tRNA binding surface [nucleotide binding]; other site
393115003650	anticodon binding site; other site
393115003651	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
393115003652	dimer interface [polypeptide binding]; other site
393115003653	putative tRNA-binding site [nucleotide binding]; other site
393115003654	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003655	D-galactonate transporter; Region: 2A0114; TIGR00893
393115003656	putative substrate translocation pore; other site
393115003657	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
393115003658	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
393115003659	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
393115003660	Intracellular septation protein A; Region: IspA; pfam04279
393115003661	Glucokinase; Region: Glucokinase; pfam02685
393115003662	glucokinase, proteobacterial type; Region: glk; TIGR00749
393115003663	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
393115003664	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115003665	S-adenosylmethionine binding site [chemical binding]; other site
393115003666	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
393115003667	ABC1 family; Region: ABC1; cl17513
393115003668	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
393115003669	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
393115003670	nucleotide binding site/active site [active]
393115003671	HIT family signature motif; other site
393115003672	catalytic residue [active]
393115003673	Similar to Q8A404 Putative amidophosphoribosyl-transferase from Bacteroides thetaiotaomicron (235 aa). FASTA: opt: 247 Z-score: 317.1 E(): 9e-10 Smith-Waterman score: 247; 26.699identity in 206 aa overlap. Contains a frameshift after aa 121 ORF ftt1301c
393115003674	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
393115003675	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
393115003676	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
393115003677	FAD binding domain; Region: FAD_binding_4; pfam01565
393115003678	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
393115003679	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
393115003680	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
393115003681	putative active site [active]
393115003682	GTP-binding protein Der; Reviewed; Region: PRK00093
393115003683	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
393115003684	G1 box; other site
393115003685	GTP/Mg2+ binding site [chemical binding]; other site
393115003686	Switch I region; other site
393115003687	G2 box; other site
393115003688	Switch II region; other site
393115003689	G3 box; other site
393115003690	G4 box; other site
393115003691	G5 box; other site
393115003692	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
393115003693	G1 box; other site
393115003694	GTP/Mg2+ binding site [chemical binding]; other site
393115003695	Switch I region; other site
393115003696	G2 box; other site
393115003697	G3 box; other site
393115003698	Switch II region; other site
393115003699	G4 box; other site
393115003700	G5 box; other site
393115003701	ISFtu1, fragment. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. Stop codon at position 136 relative to full length ISftu1
393115003702	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
393115003703	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115003704	Walker A motif; other site
393115003705	ATP binding site [chemical binding]; other site
393115003706	Walker B motif; other site
393115003707	arginine finger; other site
393115003708	Peptidase family M41; Region: Peptidase_M41; pfam01434
393115003709	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115003710	putative transporter; Provisional; Region: PRK10504
393115003711	putative substrate translocation pore; other site
393115003712	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
393115003713	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
393115003714	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
393115003715	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
393115003716	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
393115003717	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
393115003718	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
393115003719	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
393115003720	Type II transport protein GspH; Region: GspH; pfam12019
393115003721	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
393115003722	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
393115003723	active site
393115003724	dimer interface [polypeptide binding]; other site
393115003725	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
393115003726	dimer interface [polypeptide binding]; other site
393115003727	active site
393115003728	Thiamine pyrophosphokinase; Region: TPK; cd07995
393115003729	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
393115003730	active site
393115003731	dimerization interface [polypeptide binding]; other site
393115003732	thiamine binding site [chemical binding]; other site
393115003733	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
393115003734	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
393115003735	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
393115003736	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
393115003737	active site
393115003738	multifunctional aminopeptidase A; Provisional; Region: PRK00913
393115003739	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
393115003740	interface (dimer of trimers) [polypeptide binding]; other site
393115003741	Substrate-binding/catalytic site; other site
393115003742	Zn-binding sites [ion binding]; other site
393115003743	Predicted permeases [General function prediction only]; Region: COG0795
393115003744	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
393115003745	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
393115003746	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
393115003747	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
393115003748	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
393115003749	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
393115003750	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
393115003751	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
393115003752	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
393115003753	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
393115003754	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
393115003755	Predicted membrane protein [Function unknown]; Region: COG2860
393115003756	UPF0126 domain; Region: UPF0126; pfam03458
393115003757	UPF0126 domain; Region: UPF0126; pfam03458
393115003758	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
393115003759	active site
393115003760	dinuclear metal binding site [ion binding]; other site
393115003761	dimerization interface [polypeptide binding]; other site
393115003762	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
393115003763	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
393115003764	active site
393115003765	catalytic motif [active]
393115003766	Zn binding site [ion binding]; other site
393115003767	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
393115003768	FAD binding domain; Region: FAD_binding_4; pfam01565
393115003769	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
393115003770	phosphoglyceromutase; Provisional; Region: PRK05434
393115003771	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
393115003772	seryl-tRNA synthetase; Provisional; Region: PRK05431
393115003773	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
393115003774	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
393115003775	dimer interface [polypeptide binding]; other site
393115003776	active site
393115003777	motif 1; other site
393115003778	motif 2; other site
393115003779	motif 3; other site
393115003780	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
393115003781	ROK family; Region: ROK; pfam00480
393115003782	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
393115003783	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
393115003784	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
393115003785	Walker A/P-loop; other site
393115003786	ATP binding site [chemical binding]; other site
393115003787	Q-loop/lid; other site
393115003788	ABC transporter signature motif; other site
393115003789	Walker B; other site
393115003790	D-loop; other site
393115003791	H-loop/switch region; other site
393115003792	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
393115003793	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
393115003794	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
393115003795	Walker A/P-loop; other site
393115003796	ATP binding site [chemical binding]; other site
393115003797	Q-loop/lid; other site
393115003798	ABC transporter signature motif; other site
393115003799	Walker B; other site
393115003800	D-loop; other site
393115003801	H-loop/switch region; other site
393115003802	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
393115003803	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
393115003804	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
393115003805	homotrimer interaction site [polypeptide binding]; other site
393115003806	putative active site [active]
393115003807	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
393115003808	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
393115003809	Sulfate transporter family; Region: Sulfate_transp; pfam00916
393115003810	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
393115003811	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
393115003812	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115003813	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
393115003814	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
393115003815	Peptidase family M50; Region: Peptidase_M50; pfam02163
393115003816	active site
393115003817	putative substrate binding region [chemical binding]; other site
393115003818	Neurotransmitter-gated ion-channel ligand binding domain; Region: Neur_chan_LBD; pfam02931
393115003819	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
393115003820	Gentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3435
393115003821	RNA polymerase beta'' subunit; Reviewed; Region: rpoC2; CHL00117
393115003822	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
393115003823	Domain of unknown function (DUF4280); Region: DUF4280; pfam14107
393115003824	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; cl01370
393115003825	Intracellular growth locus C protein; Region: IglC; pfam11550
393115003826	Protein of unknown function (DUF877); Region: DUF877; pfam05943
393115003827	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
393115003828	type VI secretion protein, VC_A0107 family; Region: VI_chp_5; TIGR03358
393115003829	Similar to AAP09359 (Q81DH0) Hypothetical protein from Bacillus cereus (393 aa). FASTA: opt: 1167 Z-score: 1358.6 E(): 8e-68 Smith-Waterman score: 1167; 48.413 identity in 378 aa overlap. Contains 2 in-frame stop codons after aa 199 and 336 Identical to FTF1716. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1361c
393115003830	Similar to AAO90848 (Q83BZ2) Major facilitator family transporter from Coxiella burnetii (429 aa). FASTA: opt: 816 Z-score: 918.3 E(): 2.7e-43 Smith-Waterman score: 1063; 41.966 identity in 417 aa overlap. CDS contains a frameshift after aa 49 and is also interrupted by an IS element Identical to FTF1717 upto aa 307. It is part of the duplicated region 1374371..1408281 (again upto aa 307) which is identical to 1767715..1801625 ORF ftt1362
393115003831	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115003832	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115003833	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115003834	Similar to AAO90849 (Q83BZ1) Trehalase from Coxiella burnetii (543 aa). FASTA: opt: 841 Z-score: 963.6 E(): 8e-46 Smith-Waterman score: 1352; 43.373 identity in 498 aa overlap. Contains 2 in-frame stop codons after aa 71 and 140
393115003835	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
393115003836	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
393115003837	intersubunit interface [polypeptide binding]; other site
393115003838	active site
393115003839	zinc binding site [ion binding]; other site
393115003840	Na+ binding site [ion binding]; other site
393115003841	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
393115003842	pyruvate kinase; Provisional; Region: PRK05826
393115003843	domain interfaces; other site
393115003844	active site
393115003845	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
393115003846	Phosphoglycerate kinase; Region: PGK; pfam00162
393115003847	substrate binding site [chemical binding]; other site
393115003848	hinge regions; other site
393115003849	ADP binding site [chemical binding]; other site
393115003850	catalytic site [active]
393115003851	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
393115003852	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
393115003853	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
393115003854	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
393115003855	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
393115003856	TPP-binding site [chemical binding]; other site
393115003857	dimer interface [polypeptide binding]; other site
393115003858	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
393115003859	PYR/PP interface [polypeptide binding]; other site
393115003860	dimer interface [polypeptide binding]; other site
393115003861	TPP binding site [chemical binding]; other site
393115003862	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
393115003863	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
393115003864	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
393115003865	putative phosphate acyltransferase; Provisional; Region: PRK05331
393115003866	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
393115003867	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
393115003868	dimer interface [polypeptide binding]; other site
393115003869	active site
393115003870	CoA binding pocket [chemical binding]; other site
393115003871	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
393115003872	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
393115003873	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
393115003874	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
393115003875	NAD(P) binding site [chemical binding]; other site
393115003876	homotetramer interface [polypeptide binding]; other site
393115003877	homodimer interface [polypeptide binding]; other site
393115003878	active site
393115003879	acyl carrier protein; Provisional; Region: acpP; PRK00982
393115003880	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
393115003881	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
393115003882	dimer interface [polypeptide binding]; other site
393115003883	active site
393115003884	Similar to Q8F211 Conserved hypothetical protein from Letpospira interrogans (104 aa) opt: 154 Z-score: 241.8 E(): 1.3e-05 Smith-Waterman score: 154; 44.068 identity in 59 aa overlap. Truncation at C-terminal according to FASTA hits ORF ftt1378
393115003885	Similar to Q886E0 Oxidoreductase, FAD-binding from Pseudomonas syringae (660 aa) opt: 552 Z-score: 641.8 E(): 6.7e-28 Smith-Waterman score: 552; 38.057 identity in 247 aa overlap. Contains a frameshift after aa 228. Truncation at C-terminal according to FASTA hits ORF ftt1379c
393115003886	Similar to Q89A60 Putative transport protein from Buchnera aphidicola (388 aa). FASTA: opt: 636 Z-score: 709.7 E(): 1.1e-31 636; Smith-Waterman score: 636; 29.793 identity in 386 aa overlap. Contains a frameshift after aa 119 ORF ftt1380
393115003887	Similar to AAP17579 (P33019) Hypothetical protein yeiH from E. coli (349 aa). FASTA: opt: 1005 Z-score: 1126.5 E(): 6.8e-55 Smith-Waterman score: 1005; 49.292 identity in 353 aa overlap. Contains an in-frame stop codon after aa 244 ORF ftt1381
393115003888	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
393115003889	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
393115003890	active site
393115003891	dimerization interface [polypeptide binding]; other site
393115003892	16S rRNA methyltransferase B; Provisional; Region: PRK10901
393115003893	NusB family; Region: NusB; pfam01029
393115003894	putative RNA binding site [nucleotide binding]; other site
393115003895	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115003896	S-adenosylmethionine binding site [chemical binding]; other site
393115003897	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
393115003898	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115003899	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115003900	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115003901	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
393115003902	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
393115003903	nucleotide binding pocket [chemical binding]; other site
393115003904	K-X-D-G motif; other site
393115003905	catalytic site [active]
393115003906	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
393115003907	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
393115003908	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
393115003909	Dimer interface [polypeptide binding]; other site
393115003910	BRCT sequence motif; other site
393115003911	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
393115003912	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
393115003913	active site
393115003914	oligomerization interface [polypeptide binding]; other site
393115003915	metal binding site [ion binding]; metal-binding site
393115003916	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
393115003917	pantoate--beta-alanine ligase; Region: panC; TIGR00018
393115003918	active site
393115003919	nucleotide binding site [chemical binding]; other site
393115003920	HIGH motif; other site
393115003921	KMSKS motif; other site
393115003922	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
393115003923	tetramerization interface [polypeptide binding]; other site
393115003924	active site
393115003925	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
393115003926	nucleotide binding site [chemical binding]; other site
393115003927	Type III pantothenate kinase; Region: Pan_kinase; cl17198
393115003928	exodeoxyribonuclease V, alpha subunit; Region: recD; TIGR01447
393115003929	AAA domain; Region: AAA_30; pfam13604
393115003930	Family description; Region: UvrD_C_2; pfam13538
393115003931	exodeoxyribonuclease V, beta subunit; Region: recB; TIGR00609
393115003932	Family description; Region: UvrD_C_2; pfam13538
393115003933	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
393115003934	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
393115003935	Divergent AAA domain; Region: AAA_4; pfam04326
393115003936	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
393115003937	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
393115003938	putative DNA binding site [nucleotide binding]; other site
393115003939	putative Zn2+ binding site [ion binding]; other site
393115003940	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
393115003941	Exodeoxyribonuclease V, gamma subunit; Region: Exonuc_V_gamma; pfam04257
393115003942	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
393115003943	Similar to AAO90712 (Q83CC4) Hypothetical protein CBU1203 from Coxiella burnetti (550 aa). FASTA: opt: opt: 1847 Z-score: 2115.4 E(): 5.6e-110 Smith-Waterman score: 1847; 52.075 identity in 530 aa overlap. Contains a frameshift after aa 309 ORF ftt1398c
393115003944	EamA-like transporter family; Region: EamA; pfam00892
393115003945	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
393115003946	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
393115003947	non-specific DNA binding site [nucleotide binding]; other site
393115003948	salt bridge; other site
393115003949	sequence-specific DNA binding site [nucleotide binding]; other site
393115003950	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
393115003951	Catalytic site [active]
393115003952	FeoA domain; Region: FeoA; cl00838
393115003953	Sporulation related domain; Region: SPOR; pfam05036
393115003954	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
393115003955	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
393115003956	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
393115003957	active site
393115003958	Fe-S metabolism associated domain; Region: SufE; cl00951
393115003959	Disulfide bond formation protein DsbB; Region: DsbB; cl00649
393115003960	Similar to Q8GLC1 ORF1 transposase from Acinetobacter baumannii (180 aa) fasta scores; opt: 343 Z-score: 433.4 E(): 2.7e-16 37.500 identity in 160 aa overlap Frameshift after aa's 165 and 252 and stop codon at 263. Mmeber of the IS4 family of insertion sequences. ORF ftt1411
393115003961	prolyl-tRNA synthetase; Provisional; Region: PRK09194
393115003962	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
393115003963	dimer interface [polypeptide binding]; other site
393115003964	motif 1; other site
393115003965	active site
393115003966	motif 2; other site
393115003967	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
393115003968	putative deacylase active site [active]
393115003969	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
393115003970	active site
393115003971	motif 3; other site
393115003972	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
393115003973	anticodon binding site; other site
393115003974	methionine aminotransferase; Validated; Region: PRK09082
393115003975	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
393115003976	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115003977	homodimer interface [polypeptide binding]; other site
393115003978	catalytic residue [active]
393115003979	Protein of unknown function (DUF3568); Region: DUF3568; pfam12092
393115003980	C-N hydrolase family amidase; Provisional; Region: PRK10438
393115003981	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
393115003982	putative active site [active]
393115003983	catalytic triad [active]
393115003984	dimer interface [polypeptide binding]; other site
393115003985	multimer interface [polypeptide binding]; other site
393115003986	transcription antitermination factor NusB; Region: nusB; TIGR01951
393115003987	putative RNA binding site [nucleotide binding]; other site
393115003988	hypothetical protein; Provisional; Region: PRK05170
393115003989	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
393115003990	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
393115003991	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
393115003992	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
393115003993	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
393115003994	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
393115003995	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
393115003996	active site residue [active]
393115003997	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
393115003998	active site residue [active]
393115003999	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004000	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004001	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004002	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
393115004003	Coenzyme A binding pocket [chemical binding]; other site
393115004004	Similar to Q8P215 Hypothetical protein spyM18_0602 from (244 aa). FASTA: opt: 134 Z-score: 160.0 E(): 0.46 Smith-Waterman score: 134; 26.357 identity in 129 aa overlap. Contains a frameshift after aa 85. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1429c
393115004005	Similarity to Q8DCC3 tRNA (guanine-N(7)-)-methyltransferase (239 aa). FASTA: opt: 527 Z-score: 633.6 E(): 1.9e-27 Smith-Waterman score: 527; 54.861 identity in 144 aa overlap. Truncation at C-terminal according to FASTA hits ORF ftt1430c
393115004006	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
393115004007	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
393115004008	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
393115004009	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
393115004010	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
393115004011	Ligand binding site; other site
393115004012	Putative Catalytic site; other site
393115004013	DXD motif; other site
393115004014	inner membrane transport permease; Provisional; Region: PRK15066
393115004015	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
393115004016	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
393115004017	ATP-binding cassette domain of the lipid transporters, subfamily A; Region: ABC_subfamily_A; cd03263
393115004018	Walker A/P-loop; other site
393115004019	ATP binding site [chemical binding]; other site
393115004020	Q-loop/lid; other site
393115004021	ABC transporter signature motif; other site
393115004022	Walker B; other site
393115004023	D-loop; other site
393115004024	H-loop/switch region; other site
393115004025	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
393115004026	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115004027	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
393115004028	Similar to AAP07946 (Q813X1)Hypothetical Membrane Spanning Protein from Bacillus cereus (255 aa). FASTA: opt: 611 Z-score: 715.3 E(): 5.4e-32 Smith-Waterman score: 611; 40.323identity in 248 aa overlap. Contains a frameshift after aa 131 ORF ftt1437c
393115004029	Similar to P73134 Hypothetical protein from Synechocystis sp. (104 aa). FASTA: 233 Z-score: 308.2 E(): 2.6e-09 Smith-Waterman score: 233; 41.584 identity in 101 aa overlap. Contains a frameshift after aa 18 ORF ftt1438c
393115004030	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
393115004031	active site
393115004032	Similar to Q8XAW5 Putative transport protein from E.coli (475 aa). FASTA: opt: 517 Z-score: 580.9 E(): 1.7e-24 Smith-Waterman score: 517; 27.007 identity in 411 aa overlap . Contains a frameshift after aa 45 ORF ftt1440c
393115004033	Ferritin-like domain; Region: Ferritin; pfam00210
393115004034	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
393115004035	dinuclear metal binding motif [ion binding]; other site
393115004036	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
393115004037	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
393115004038	dimer interface [polypeptide binding]; other site
393115004039	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
393115004040	recombination factor protein RarA; Provisional; Region: PRK14700
393115004041	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
393115004042	exopolyphosphatase; Region: exo_poly_only; TIGR03706
393115004043	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
393115004044	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
393115004045	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
393115004046	catalytic residues [active]
393115004047	transcription termination factor Rho; Provisional; Region: rho; PRK09376
393115004048	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
393115004049	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
393115004050	RNA binding site [nucleotide binding]; other site
393115004051	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
393115004052	multimer interface [polypeptide binding]; other site
393115004053	Walker A motif; other site
393115004054	ATP binding site [chemical binding]; other site
393115004055	Walker B motif; other site
393115004056	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
393115004057	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
393115004058	active site
393115004059	substrate binding site [chemical binding]; other site
393115004060	metal binding site [ion binding]; metal-binding site
393115004061	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
393115004062	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
393115004063	Substrate binding site; other site
393115004064	Cupin domain; Region: Cupin_2; cl17218
393115004065	ISFtu1, fragment. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. deletion of carboxy terminal region between aa 135 and 238 relative to full length ISftu1.
393115004066	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
393115004067	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
393115004068	NAD binding site [chemical binding]; other site
393115004069	substrate binding site [chemical binding]; other site
393115004070	homodimer interface [polypeptide binding]; other site
393115004071	active site
393115004072	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
393115004073	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
393115004074	substrate binding site; other site
393115004075	tetramer interface; other site
393115004076	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
393115004077	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
393115004078	active site
393115004079	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
393115004080	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
393115004081	hypothetical protein; Provisional; Region: PRK07579
393115004082	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
393115004083	active site
393115004084	cosubstrate binding site; other site
393115004085	substrate binding site [chemical binding]; other site
393115004086	catalytic site [active]
393115004087	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
393115004088	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
393115004089	inhibitor-cofactor binding pocket; inhibition site
393115004090	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115004091	catalytic residue [active]
393115004092	Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]; Region: AsnB; COG0367
393115004093	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
393115004094	active site
393115004095	dimer interface [polypeptide binding]; other site
393115004096	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
393115004097	Ligand Binding Site [chemical binding]; other site
393115004098	Molecular Tunnel; other site
393115004099	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
393115004100	This family is most closely related to the GT1 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis; Region: GT1_WbnK_like; cd03807
393115004101	putative ADP-binding pocket [chemical binding]; other site
393115004102	Vi polysaccharide biosynthesis protein TviC; Provisional; Region: PRK15181
393115004103	UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs; Region: UDP_AE_SDR_e; cd05256
393115004104	NAD binding site [chemical binding]; other site
393115004105	substrate binding site [chemical binding]; other site
393115004106	homodimer interface [polypeptide binding]; other site
393115004107	active site
393115004108	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
393115004109	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
393115004110	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
393115004111	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
393115004112	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
393115004113	putative ADP-binding pocket [chemical binding]; other site
393115004114	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115004115	NADH(P)-binding; Region: NAD_binding_10; pfam13460
393115004116	NAD(P) binding site [chemical binding]; other site
393115004117	active site
393115004118	Bacterial sugar transferase; Region: Bac_transf; pfam02397
393115004119	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
393115004120	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
393115004121	NAD(P) binding site [chemical binding]; other site
393115004122	homodimer interface [polypeptide binding]; other site
393115004123	substrate binding site [chemical binding]; other site
393115004124	active site
393115004125	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
393115004126	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115004127	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
393115004128	Similarity to Q82NX6 Putative adenosine deaminase from Streptomyces avermitilis (354 aa). FASTA: opt: 503 Z-score: 606.1 E(): 6.6e-26 Smith-Waterman score: 503; 35.636 identity in 275 aa overlap. Contains a frameshift after aa 45. Truncation a C-terminal according to FASTA hits.
393115004129	L-aspartate oxidase; Provisional; Region: PRK09077
393115004130	L-aspartate oxidase; Provisional; Region: PRK06175
393115004131	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
393115004132	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
393115004133	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
393115004134	dimerization interface [polypeptide binding]; other site
393115004135	active site
393115004136	quinolinate synthetase; Provisional; Region: PRK09375
393115004137	Guanylate kinase; Region: Guanylate_kin; pfam00625
393115004138	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
393115004139	catalytic site [active]
393115004140	G-X2-G-X-G-K; other site
393115004141	helicase 45; Provisional; Region: PTZ00424
393115004142	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
393115004143	ATP binding site [chemical binding]; other site
393115004144	Mg++ binding site [ion binding]; other site
393115004145	motif III; other site
393115004146	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115004147	nucleotide binding region [chemical binding]; other site
393115004148	ATP-binding site [chemical binding]; other site
393115004149	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
393115004150	putative RNA binding site [nucleotide binding]; other site
393115004151	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
393115004152	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
393115004153	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
393115004154	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115004155	putative substrate translocation pore; other site
393115004156	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115004157	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
393115004158	putative substrate translocation pore; other site
393115004159	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115004160	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
393115004161	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
393115004162	dimer interface [polypeptide binding]; other site
393115004163	active site
393115004164	Galactokinase [Carbohydrate transport and metabolism]; Region: GalK; COG0153
393115004165	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
393115004166	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
393115004167	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
393115004168	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
393115004169	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
393115004170	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
393115004171	Ligand binding site; other site
393115004172	oligomer interface; other site
393115004173	Uncharacterized conserved protein [Function unknown]; Region: COG2835
393115004174	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004175	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004176	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004177	Similar to Q9ZIX7 Putative transposase from Haemophilus gallinarum (216 aa). FASTA: opt: 364 Z-score: 519.1 E(): 4.6e-21 Smith-Waterman score: 364; 67.606 identity in 71 aa overlap. CDS has no start codon due to truncation at the N-terminal ORF ftt1482
393115004178	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
393115004179	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
393115004180	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
393115004181	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
393115004182	NAD binding site [chemical binding]; other site
393115004183	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
393115004184	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
393115004185	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
393115004186	E3 interaction surface; other site
393115004187	lipoyl attachment site [posttranslational modification]; other site
393115004188	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
393115004189	E3 interaction surface; other site
393115004190	lipoyl attachment site [posttranslational modification]; other site
393115004191	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
393115004192	E3 interaction surface; other site
393115004193	lipoyl attachment site [posttranslational modification]; other site
393115004194	e3 binding domain; Region: E3_binding; pfam02817
393115004195	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
393115004196	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
393115004197	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
393115004198	dimer interface [polypeptide binding]; other site
393115004199	TPP-binding site [chemical binding]; other site
393115004200	Putative S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_28; pfam02636
393115004201	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
393115004202	dephospho-CoA kinase; Region: TIGR00152
393115004203	CoA-binding site [chemical binding]; other site
393115004204	ATP-binding [chemical binding]; other site
393115004205	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
393115004206	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
393115004207	active site
393115004208	HIGH motif; other site
393115004209	dimer interface [polypeptide binding]; other site
393115004210	KMSKS motif; other site
393115004211	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
393115004212	Zeta toxin; Region: Zeta_toxin; pfam06414
393115004213	AAA domain; Region: AAA_17; cl17253
393115004214	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
393115004215	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
393115004216	putative active site [active]
393115004217	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
393115004218	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
393115004219	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
393115004220	MutS domain I; Region: MutS_I; pfam01624
393115004221	MutS domain III; Region: MutS_III; pfam05192
393115004222	MutS domain V; Region: MutS_V; pfam00488
393115004223	Walker A/P-loop; other site
393115004224	ATP binding site [chemical binding]; other site
393115004225	Q-loop/lid; other site
393115004226	ABC transporter signature motif; other site
393115004227	Walker B; other site
393115004228	D-loop; other site
393115004229	H-loop/switch region; other site
393115004230	preprotein translocase subunit SecB; Validated; Region: PRK05751
393115004231	SecA binding site; other site
393115004232	Preprotein binding site; other site
393115004233	Similar to Q8CK83 Hypothetical protein from Yersinia pestis (424 aa). FASTA: opt: 297 Z-score: 337.7 bits: 71.5 E(): 5.9e-11 Smith-Waterman score: 298; 24.884 identity in 430 aa overlap. Contains an in-frame stop codon after aa 343 ORF ftt1501
393115004234	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
393115004235	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
393115004236	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
393115004237	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
393115004238	active site
393115004239	DNA binding site [nucleotide binding]
393115004240	Int/Topo IB signature motif; other site
393115004241	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115004242	S-adenosylmethionine binding site [chemical binding]; other site
393115004243	Domain of unknown function (DUF4124); Region: DUF4124; pfam13511
393115004244	Domain of unknown function (DUF4124); Region: DUF4124; pfam13511
393115004245	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
393115004246	HD domain; Region: HD_4; pfam13328
393115004247	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
393115004248	synthetase active site [active]
393115004249	NTP binding site [chemical binding]; other site
393115004250	metal binding site [ion binding]; metal-binding site
393115004251	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
393115004252	Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in...; Region: PI3Ka; cl00271
393115004253	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
393115004254	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
393115004255	EamA-like transporter family; Region: EamA; pfam00892
393115004256	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
393115004257	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
393115004258	HSP70 interaction site [polypeptide binding]; other site
393115004259	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
393115004260	substrate binding site [polypeptide binding]; other site
393115004261	dimer interface [polypeptide binding]; other site
393115004262	Similar to Q9HT63 Probable transporter from Pseudomonas aeruginosa (449 aa). FASTA: opt: 476 Z-score: 561.3 E(): 2e-23 Smith-Waterman score: 476; 36.283 identity in 226 aa overlap. Truncated at C-terminal according to FASTA hits ORF ftt1513
393115004263	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
393115004264	Similar to Q92SF1 putative mercuric reductase protein from Rizobium meliloti (473aa). FASTA: opt: 1257 Z-score: 1348.4 E(): 2.9e-67 Smith-Waterman score: 1257; 41.895 identity in 475 aa overlap. Contains an in-frame stop codon after aa 358
393115004265	Uncharacterized conserved protein [Function unknown]; Region: COG0398
393115004266	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
393115004267	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
393115004268	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
393115004269	DNA binding site [nucleotide binding]
393115004270	active site
393115004271	Similar to Q87RC9 Putative outer membrane lipoprotein Slp from Vibrio parahaemolyticus (185 aa). FASTA: opt: 105 Z-score: 145.9 E(): 2.8 Smith-Waterman score: 105; 26.271identity in 118 aa overlap. Contains an in-frame stop codon after aa 32 and truncation at the C-terminal according to the FASTA matches ORF ftt1519
393115004272	Amino acid permease; Region: AA_permease_2; pfam13520
393115004273	Similar to Q8A800 diaminopimelate decarboxylase from Bacteroides thetaiotamicron (386 aa). FASTA: opt: 913 Z-score: 1066.5 E(): 1.5e-51 Smith-Waterman score: 1118; 48.000 identity in 375 aa overlap. Contains a frameshift after aa 924
393115004274	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3786
393115004275	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
393115004276	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
393115004277	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
393115004278	DEAD-like helicases superfamily; Region: DEXDc; smart00487
393115004279	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
393115004280	ATP binding site [chemical binding]; other site
393115004281	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
393115004282	putative Mg++ binding site [ion binding]; other site
393115004283	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115004284	nucleotide binding region [chemical binding]; other site
393115004285	ATP-binding site [chemical binding]; other site
393115004286	Helicase associated domain (HA2); Region: HA2; pfam04408
393115004287	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
393115004288	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
393115004289	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
393115004290	Monomeric isocitrate dehydrogenase [Energy production and conversion]; Region: Icd; COG2838
393115004291	Monomeric isocitrate dehydrogenase; Region: IDH; cl15383
393115004292	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
393115004293	ArsC family; Region: ArsC; pfam03960
393115004294	catalytic residues [active]
393115004295	Long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07059
393115004296	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
393115004297	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
393115004298	acyl-activating enzyme (AAE) consensus motif; other site
393115004299	putative AMP binding site [chemical binding]; other site
393115004300	putative active site [active]
393115004301	putative CoA binding site [chemical binding]; other site
393115004302	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
393115004303	Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771
393115004304	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
393115004305	active site
393115004306	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
393115004307	Acyl CoA binding protein; Region: ACBP; pfam00887
393115004308	acyl-CoA binding pocket [chemical binding]; other site
393115004309	CoA binding site [chemical binding]; other site
393115004310	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
393115004311	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
393115004312	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
393115004313	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
393115004314	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
393115004315	substrate binding site [chemical binding]; other site
393115004316	oxyanion hole (OAH) forming residues; other site
393115004317	trimer interface [polypeptide binding]; other site
393115004318	acetyl-CoA acetyltransferase; Provisional; Region: PRK09052
393115004319	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
393115004320	dimer interface [polypeptide binding]; other site
393115004321	active site
393115004322	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
393115004323	CoenzymeA binding site [chemical binding]; other site
393115004324	subunit interaction site [polypeptide binding]; other site
393115004325	PHB binding site; other site
393115004326	Similar to Q9ZNS0 Putative sugar transporter from Aribdopsis thaliana (508 aa). FASTA: opt: 409 Z-score: 463.9 E(): 5.5e-18 Smith-Waterman score: 499; 27.171 identity in 449 aa overlap. Contains a frameshift and a possible internal deletion of ~50 aa after aa 199 ORF ftt1533c
393115004327	putative nicotinate phosphoribosyltransferase; Provisional; Region: PRK09198
393115004328	pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general; Region: PBEF_like; cd01569
393115004329	active site
393115004330	Similar to OCD_AGRT5 (P09773) Ornithine cyclodeaminase from Agrobacterium tumefaciens (354 aa). FASTA: opt: 1034 Z-score: 1225.5 E(): 2.1e-60 Smith-Waterman score: 1034; 52.288 identity in 306 aa overlap. Contains a frameshift after aa 142 ORF ftt1535c
393115004331	Uncharacterized protein conserved in bacteria containing a pentein-type domain [Function unknown]; Region: COG4874
393115004332	Amidinotransferase; Region: Amidinotransf; pfam02274
393115004333	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
393115004334	uncharacterized proteobacterial lipoprotein; Region: lp_; TIGR02722
393115004335	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
393115004336	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
393115004337	active site
393115004338	phosphorylation site [posttranslational modification]
393115004339	intermolecular recognition site; other site
393115004340	dimerization interface [polypeptide binding]; other site
393115004341	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
393115004342	DNA binding site [nucleotide binding]
393115004343	Similar to Q92R87 Putative sensor histidine kinase transmembrane protein from Rhizobium meliloti (465 aa). FASTA: opt: 509 Z-score: 555.0 E(): 4.6e-23 Smith-Waterman score: 512; 31.023 identity in 303 aa overlap. Contains a frameshift after aa 185 ORF ftt1544
393115004344	Similar to Q9KSY6 Hypothetical protein VC1120 from Vibrio cholerae (426 aa). FASTA: opt: 1106 Z-score: 1280.0 E(): 1.9e-63 Smith-Waterman score: 1106; 41.827 identity in 416 aa overlap. Contains a frameshift after aa 160 ORF ftt1545
393115004345	Similar to Q984A5 Hypothetical protein mll8086 from Rhizobium loti (272 aa). FASTA: opt: 464 Z-score: 572.4 E(): 4.9e-24 Smith-Waterman score: 464; 32.946 identity in 258 aa overlap. Contains 2 frameshifts after aa 54 and 146 ORF ftt1546
393115004346	Similar to Q9A8C7 Cyclopropane-fatty-acyl-phospholipid synthase from Caulobacter crescentus (409 aa). FASTA: opt: 639 Z-score: 746.0 bits: 146.9 E(): 1.1e-33 Smith-Waterman score: 904; 38.653 identity in 401 aa overlap. CDS interrupted by an IS element ORF ftt1547
393115004347	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004348	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004349	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004350	Protein of unknown function (DUF3833); Region: DUF3833; pfam12915
393115004351	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
393115004352	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
393115004353	NAD(P) binding site [chemical binding]; other site
393115004354	active site
393115004355	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
393115004356	Fatty acid desaturase; Region: FA_desaturase; pfam00487
393115004357	Di-iron ligands [ion binding]; other site
393115004358	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
393115004359	ribonuclease R; Region: RNase_R; TIGR02063
393115004360	RNB domain; Region: RNB; pfam00773
393115004361	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
393115004362	RNA binding site [nucleotide binding]; other site
393115004363	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
393115004364	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
393115004365	RNA binding site [nucleotide binding]; other site
393115004366	active site
393115004367	ribonuclease III; Reviewed; Region: rnc; PRK00102
393115004368	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
393115004369	dimerization interface [polypeptide binding]; other site
393115004370	active site
393115004371	metal binding site [ion binding]; metal-binding site
393115004372	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
393115004373	dsRNA binding site [nucleotide binding]; other site
393115004374	signal peptidase I; Provisional; Region: PRK10861
393115004375	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
393115004376	Catalytic site [active]
393115004377	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
393115004378	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
393115004379	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
393115004380	active site
393115004381	phosphorylation site [posttranslational modification]
393115004382	intermolecular recognition site; other site
393115004383	dimerization interface [polypeptide binding]; other site
393115004384	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
393115004385	DNA binding site [nucleotide binding]
393115004386	Similar to P75762 Hypothetical protein ybhH from E. coli (350 aa). FASTA: opt: opt: 818 Z-score: 956.3 E(): 2.1e-45 Smith-Waterman score: 818; 40.230 identity in 348 aa overlap. Contains a frameshift after aa 112 and an in-frame stop codon after aa 302 ORF ftt1558c
393115004387	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
393115004388	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
393115004389	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
393115004390	active site
393115004391	dimerization interface [polypeptide binding]; other site
393115004392	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
393115004393	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
393115004394	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
393115004395	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
393115004396	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
393115004397	substrate binding pocket [chemical binding]; other site
393115004398	chain length determination region; other site
393115004399	substrate-Mg2+ binding site; other site
393115004400	catalytic residues [active]
393115004401	aspartate-rich region 1; other site
393115004402	active site lid residues [active]
393115004403	aspartate-rich region 2; other site
393115004404	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
393115004405	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
393115004406	polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707
393115004407	Similar to Q8KG78 Glycosyl hydrolase, family 3 from Chlorobium tepidum (372 aa). FASTA: opt: 811 Z-score: 919.2 E(): 2.4e-43 Smith-Waterman score: 811; 40.822 identity in 365 aa overlap. Contains a frameshift after aa 28 ORF ftt1565c
393115004408	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
393115004409	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
393115004410	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
393115004411	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
393115004412	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
393115004413	active site
393115004414	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
393115004415	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
393115004416	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
393115004417	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
393115004418	trimer interface [polypeptide binding]; other site
393115004419	active site
393115004420	UDP-GlcNAc binding site [chemical binding]; other site
393115004421	lipid binding site [chemical binding]; lipid-binding site
393115004422	periplasmic chaperone; Provisional; Region: PRK10780
393115004423	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
393115004424	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
393115004425	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
393115004426	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
393115004427	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
393115004428	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
393115004429	Surface antigen; Region: Bac_surface_Ag; pfam01103
393115004430	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
393115004431	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
393115004432	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
393115004433	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
393115004434	DNA gyrase subunit A; Validated; Region: PRK05560
393115004435	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
393115004436	CAP-like domain; other site
393115004437	active site
393115004438	primary dimer interface [polypeptide binding]; other site
393115004439	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
393115004440	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
393115004441	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
393115004442	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
393115004443	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
393115004444	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
393115004445	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
393115004446	aromatic chitin/cellulose binding site residues [chemical binding]; other site
393115004447	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
393115004448	ligand binding site [chemical binding]; other site
393115004449	active site
393115004450	UGI interface [polypeptide binding]; other site
393115004451	catalytic site [active]
393115004452	Restriction endonuclease [Defense mechanisms]; Region: COG3587
393115004453	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
393115004454	ATP binding site [chemical binding]; other site
393115004455	putative Mg++ binding site [ion binding]; other site
393115004456	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_3; cd10448
393115004457	GIY-YIG motif/motif A; other site
393115004458	putative active site [active]
393115004459	putative metal binding site [ion binding]; other site
393115004460	Similar to Q9XBI6 Type III restriction-modification system enzyme Mod from Bacillus cereus (669 aa). FASTA: opt: 825 Z-score: 875.5 E(): 6.5e-41 Smith-Waterman score: 856; 35.728identity in 515 aa overlap. Contains frameshifts after aa 175 and 387. Truncation at C-terminal according to FASTA hits ORF ftt1582c
393115004461	Similar to Q9JTA5 Insertion element IS1016 transposase from serogroup A Neisseria meningitidis Z2491 (151 aa). FASTA: opt: 610 Z-score: 830.4 E(): 2.1e-38 Smith-Waterman score: 610; 74.194 identity (74.1940ngapped) in 124 aa overlap N-terminal sequence is similar to FTF1121 ORF ftt1583
393115004462	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004463	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004464	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004465	Domain of unknown function (DUF4282); Region: DUF4282; pfam14110
393115004466	Similar to Q8XT33 Probable amino-acid permease transmembrane protein from Ralstonia solanacearum (543 aa). FASTA: opt: 908 Z-score: 1045.4 E(): 2.2e-50 Smith-Waterman score: 910; 32.230identity in 453 aa overlap ORF ftt1587c
393115004467	Similar to ABC-type transporter Q8D5S9 from Vibrio vulnificus (242 aa). FASTA: opt: 99 Z-score: 146.3 E(): 2.7 Smith-Waterman score: 99; 30.337 identity in 89 aa overlap ORF ftt1588c
393115004468	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
393115004469	Methyltransferase domain; Region: Methyltransf_11; pfam08241
393115004470	VacJ like lipoprotein; Region: VacJ; cl01073
393115004471	Similar to Q9ZNL0 Chitinase A from Clostridium paraputrificum (832 aa). FASTA: opt: 196 Z-score: 216.1 E(): 0.00035 Smith-Waterman score: 203; 22.770identity in 426 aa overlap ORF ftt1592c
393115004472	Similar to Q8Y4H4 Hypothetical protein lmo2467 from Listeria monocytogenes (478 aa) opt: 362 Z-score: 427.2 E(): 6.1e-16 Smith-Waterman score: 362; 46.226 identity in 106 aa overlap ORF ftt1593c
393115004473	Transcriptional regulator [Transcription]; Region: LysR; COG0583
393115004474	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
393115004475	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
393115004476	dimerization interface [polypeptide binding]; other site
393115004477	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004478	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004479	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004480	Fumarate hydratase (Fumerase); Region: Fumerase; pfam05681
393115004481	Fumarase C-terminus; Region: Fumerase_C; pfam05683
393115004482	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
393115004483	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
393115004484	ssDNA binding site; other site
393115004485	generic binding surface II; other site
393115004486	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
393115004487	ATP binding site [chemical binding]; other site
393115004488	putative Mg++ binding site [ion binding]; other site
393115004489	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
393115004490	nucleotide binding region [chemical binding]; other site
393115004491	ATP-binding site [chemical binding]; other site
393115004492	Prokaryotic lipoprotein-attachment site; Region: LPAM_2; pfam13627
393115004493	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
393115004494	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
393115004495	septum formation inhibitor; Reviewed; Region: minC; PRK04804
393115004496	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
393115004497	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
393115004498	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
393115004499	Switch I; other site
393115004500	Switch II; other site
393115004501	cell division topological specificity factor MinE; Provisional; Region: PRK13990
393115004502	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
393115004503	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
393115004504	Walker A/P-loop; other site
393115004505	ATP binding site [chemical binding]; other site
393115004506	Q-loop/lid; other site
393115004507	ABC transporter signature motif; other site
393115004508	Walker B; other site
393115004509	D-loop; other site
393115004510	H-loop/switch region; other site
393115004511	Permease; Region: Permease; pfam02405
393115004512	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
393115004513	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
393115004514	mce related protein; Region: MCE; pfam02470
393115004515	Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; pfam05494
393115004516	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
393115004517	anti sigma factor interaction site; other site
393115004518	regulatory phosphorylation site [posttranslational modification]; other site
393115004519	BolA-like protein; Region: BolA; cl00386
393115004520	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004521	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004522	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004523	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
393115004524	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
393115004525	active site
393115004526	HIGH motif; other site
393115004527	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
393115004528	KMSKS motif; other site
393115004529	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
393115004530	tRNA binding surface [nucleotide binding]; other site
393115004531	anticodon binding site; other site
393115004532	HemK family putative methylases; Region: hemK_fam; TIGR00536
393115004533	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115004534	S-adenosylmethionine binding site [chemical binding]; other site
393115004535	Similar to AAO91456 Drug resistance transporter,Bcr/Cfl family from Coxiella burnetii (409 aa). FASTA: opt: 427 Z-score: 505.5 E(): 2.6e-20 Smith-Waterman score: 442; 29.966 identity in 297 aa overlap. Contains an in-frame stop codon after aa 57. Truncation at the C-terminal according to FASTA hits ORF ftt1618
393115004536	Similar to AAP09454 (Q81D84) Aminoglycoside N6'-acetyltransferase from Bacillus cereus (169 aa). FASTA: opt: 317 Z-score: 407.6 E(): 7.5e-15 Smith-Waterman score: 317; 36.879 identity in 141 aa overlap. Contains an in-frame stop codon after aa 28 ORF ftt1619
393115004537	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004538	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004539	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004540	Tfp pilus assembly protein PilW [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilW; COG4966
393115004541	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
393115004542	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
393115004543	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
393115004544	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
393115004545	Domain of unknown function DUF21; Region: DUF21; pfam01595
393115004546	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
393115004547	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
393115004548	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
393115004549	DXD motif; other site
393115004550	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
393115004551	Na binding site [ion binding]; other site
393115004552	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
393115004553	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
393115004554	putative active site [active]
393115004555	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945
393115004556	lysine transporter; Provisional; Region: PRK10836
393115004557	PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_6; cd03396
393115004558	active site
393115004559	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
393115004560	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
393115004561	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
393115004562	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
393115004563	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
393115004564	Cation transport protein; Region: TrkH; cl17365
393115004565	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
393115004566	Similar to PROQ_HAEIN P44286 ProP effector homolog from Haemphilus influenzae (209 aa). FASTA: opt: 201 Z-score: 237.4 bits: 51.8 E(): 2.3e-05 Smith-Waterman score: 201; 28.365identity in 208 aa overlap. CDS has an extended N-terminal sequence and a truncated C-terminal sequence according to FASTA hits ORF ftt1640c
393115004567	Similar to Q8RN28 HsdR from Campylobacter jejuni (1031 aa). FASTA: 647 Z-score: 728.9 E(): 9.4e-33 Smith-Waterman score: 649; 57.222 identity in 180 aa overlap. No start codon due to truncation at N-terminal according to FASTA hits. FTF1641c also has a partial match to Q8RN31 (110-360 aa). Potential deletion between FTF1641c and FTF1642c
393115004568	Similar to Q8RN31 HsdR from Campylobacter jejuni (1031 aa). FASTA: opt: 972 Z-score: 1176.4 E(): 1.1e-57 Smith-Waterman score: 972; 66.063identity in 221 aa overlap. This CDS lacks a start codon due to an interruption of an ISFtu1 element at the N-terminal end. It is also truncated at the C-terminal according to FASTA hits. FTF1642c also has a partial match to Q8RN31 (900 to end aa). Potential deletion between FTF1641c and FTF1642c
393115004569	ISFtu1, pseudogene. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 Putative transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 putative transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. Additional frameshift at aa 131
393115004570	Glycosyl hydrolases family 32 N-terminal domain; Region: Glyco_hydro_32N; pfam00251
393115004571	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
393115004572	substrate binding [chemical binding]; other site
393115004573	active site
393115004574	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
393115004575	Major Facilitator Superfamily; Region: MFS_1; pfam07690
393115004576	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115004577	putative substrate translocation pore; other site
393115004578	D-tyrosyl-tRNA(Tyr) deacylase; Provisional; Region: PRK05273
393115004579	putative active site [active]
393115004580	dimerization interface [polypeptide binding]; other site
393115004581	putative tRNAtyr binding site [nucleotide binding]; other site
393115004582	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
393115004583	phosphate binding site [ion binding]; other site
393115004584	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
393115004585	active site
393115004586	dimer interface [polypeptide binding]; other site
393115004587	Similar to Q87VL0 Transglutaminase-like superfamily domain protein from Pseudomonas syringae (1092 aa). FASTA: opt: 4030 Z-score: 4586.9 bits: 860.5 E(): 0 Smith-Waterman score: 4030; 53.724 identity in 1074 aa overlap. Contains a stop codon after aa 769 ORF ftt1649
393115004588	Chorismate mutase type II; Region: CM_2; smart00830
393115004589	SOUL heme-binding protein; Region: SOUL; pfam04832
393115004590	Transcriptional regulator [Transcription]; Region: LysR; COG0583
393115004591	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
393115004592	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
393115004593	dimerization interface [polypeptide binding]; other site
393115004594	Protein of unknown function (DUF3568); Region: DUF3568; pfam12092
393115004595	HlyD family secretion protein; Region: HlyD; pfam00529
393115004596	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
393115004597	HlyD family secretion protein; Region: HlyD_3; pfam13437
393115004598	Protein of unknown function (DUF1415); Region: DUF1415; pfam07209
393115004599	Domain of unknown function (DUF4325); Region: DUF4325; pfam14213
393115004600	dihydroorotase; Reviewed; Region: PRK09236
393115004601	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
393115004602	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
393115004603	active site
393115004604	thiopurine S-methyltransferase; Reviewed; Region: PRK13256
393115004605	Similar to Q9APF7 Major acid phosphatase from Legionella pneumophila (395 aa). FASTA: opt 803 Z-score: 934.8 E(): 3.2e-44 Smith-Waterman score: 803; 39.359 identity in 343 aa overlap. Contains an in-frame stop codon after aa 159. ORF ftt1662c
393115004606	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
393115004607	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
393115004608	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
393115004609	catalytic site [active]
393115004610	subunit interface [polypeptide binding]; other site
393115004611	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
393115004612	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
393115004613	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
393115004614	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
393115004615	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
393115004616	ATP-grasp domain; Region: ATP-grasp_4; cl17255
393115004617	MGS-like domain. This domain composes the whole protein of methylglyoxal synthetase, which catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The family also includes the C-terminal domain in carbamoyl phosphate...; Region: MGS-like; cl00245
393115004618	substrate binding site [chemical binding]; other site
393115004619	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
393115004620	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
393115004621	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
393115004622	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
393115004623	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
393115004624	NAD binding site [chemical binding]; other site
393115004625	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
393115004626	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
393115004627	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
393115004628	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004629	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004630	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004631	Similar to Q88AM3 Na+/H+ antiporter NhaP from Pseudomonas putida (419 aa). FASTA: opt: 400 z-score: 489.1 E(): 2.2e-19 Smith-Waterman score: 411; 36.458 identity in 192 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element occurring causing a truncation at the C-terminal end.
393115004632	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
393115004633	catalytic motif [active]
393115004634	Zn binding site [ion binding]; other site
393115004635	RibD C-terminal domain; Region: RibD_C; pfam01872
393115004636	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
393115004637	Lumazine binding domain; Region: Lum_binding; pfam00677
393115004638	Lumazine binding domain; Region: Lum_binding; pfam00677
393115004639	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
393115004640	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
393115004641	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
393115004642	dimerization interface [polypeptide binding]; other site
393115004643	active site
393115004644	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
393115004645	homopentamer interface [polypeptide binding]; other site
393115004646	active site
393115004647	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
393115004648	active site
393115004649	catalytic residues [active]
393115004650	metal binding site [ion binding]; metal-binding site
393115004651	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
393115004652	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
393115004653	GTP-binding protein LepA; Provisional; Region: PRK05433
393115004654	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
393115004655	G1 box; other site
393115004656	putative GEF interaction site [polypeptide binding]; other site
393115004657	GTP/Mg2+ binding site [chemical binding]; other site
393115004658	Switch I region; other site
393115004659	G2 box; other site
393115004660	G3 box; other site
393115004661	Switch II region; other site
393115004662	G4 box; other site
393115004663	G5 box; other site
393115004664	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
393115004665	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
393115004666	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
393115004667	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
393115004668	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
393115004669	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
393115004670	dimer interface [polypeptide binding]; other site
393115004671	active site
393115004672	Similar to AAP08939 (Q81EK2) Hypothetical protein from Bacillus cereus (755 aa). FASTA: opt: 1438 Z-score: 1569.7 E(): 1.4e-79 Smith-Waterman score: 1459; 32.429 identity in 737 aa overlap. Contains a frameshift after aa 234 and an in-frame stop codon after aa 314 ORF ftt1682
393115004673	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115004674	putative substrate translocation pore; other site
393115004675	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
393115004676	Transcriptional regulator [Transcription]; Region: LysR; COG0583
393115004677	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
393115004678	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
393115004679	putative effector binding pocket; other site
393115004680	dimerization interface [polypeptide binding]; other site
393115004681	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
393115004682	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
393115004683	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
393115004684	catalytic residue [active]
393115004685	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
393115004686	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
393115004687	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
393115004688	aromatic amino acid transport protein; Region: araaP; TIGR00837
393115004689	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
393115004690	Nitroreductase family. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source...; Region: Nitroreductase; cd02136
393115004691	putative FMN binding site [chemical binding]; other site
393115004692	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004693	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004694	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004695	hypothetical protein; Validated; Region: PRK02101
393115004696	Predicted membrane protein [Function unknown]; Region: COG4125
393115004697	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
393115004698	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
393115004699	oligomerisation interface [polypeptide binding]; other site
393115004700	mobile loop; other site
393115004701	roof hairpin; other site
393115004702	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
393115004703	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
393115004704	ring oligomerisation interface [polypeptide binding]; other site
393115004705	ATP/Mg binding site [chemical binding]; other site
393115004706	stacking interactions; other site
393115004707	hinge regions; other site
393115004708	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004709	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004710	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004711	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
393115004712	NAD binding site [chemical binding]; other site
393115004713	RNA polymerase beta'' subunit; Reviewed; Region: rpoC2; CHL00117
393115004714	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
393115004715	Domain of unknown function (DUF4280); Region: DUF4280; pfam14107
393115004716	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; cl01370
393115004717	Intracellular growth locus C protein; Region: IglC; pfam11550
393115004718	Protein of unknown function (DUF877); Region: DUF877; pfam05943
393115004719	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
393115004720	type VI secretion protein, VC_A0107 family; Region: VI_chp_5; TIGR03358
393115004721	Similar to AAP09359 (Q81DH0) Hypothetical protein from Bacillus cereus (393 aa). FASTA: opt: 1167 Z-score: 1358.6 E(): 8e-68 Smith-Waterman score: 1167; 48.413 identity in 378 aa overlap. Contains 2 in-frame stop codons after aa 199 and 336. Identical to FTF1361. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1716c
393115004722	Similar to AAO90848 (Q83BZ2) Major facilitator family transporter from Coxiella burnetii (429 aa). FASTA: opt: 688 Z-score: 817.3 E(): 1.1e-37 Smith-Waterman score: 688; 40.149 identity in 269 aa overlap. CDS contains a frameshift after aa 49 and is also interrupted by an ISftu1 element. It is truncated at C-terminal due to insertion of an ISFtu1 element Identical to FTF1362 upto aa 307. It is part of the duplicated region 1767715..1801625 (again upto aa 307) which is identical to 1374371..1408281 ORF ftt1717
393115004723	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004724	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004725	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004726	Similar to MTF1_FUSNU (P34906) Modification methylase FnuDI from Fusobacterium nucleatum (344 aa). FASTA: opt: 740 Z-score: 941.7 E(): 3e-44 Smith-Waterman score: 740; 67.702 identity in 161 aa overlap. Numerous frameshifts and truncation of gene at C-terminus according to FASTA hits ORF ftt1719c
393115004727	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
393115004728	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
393115004729	dimerization interface [polypeptide binding]; other site
393115004730	ATP binding site [chemical binding]; other site
393115004731	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
393115004732	dimerization interface [polypeptide binding]; other site
393115004733	ATP binding site [chemical binding]; other site
393115004734	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
393115004735	putative active site [active]
393115004736	catalytic triad [active]
393115004737	amidophosphoribosyltransferase; Provisional; Region: PRK09246
393115004738	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
393115004739	active site
393115004740	tetramer interface [polypeptide binding]; other site
393115004741	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
393115004742	active site
393115004743	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
393115004744	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115004745	catalytic residue [active]
393115004746	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
393115004747	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
393115004748	Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: Pcm; COG2518
393115004749	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
393115004750	putative protease; Provisional; Region: PRK15452
393115004751	Peptidase family U32; Region: Peptidase_U32; pfam01136
393115004752	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
393115004753	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115004754	putative substrate translocation pore; other site
393115004755	NHAD transporter family protein; Provisional; Region: PLN00137; cl17324
393115004756	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
393115004757	Similar to Q8Y280 Probable ATP-binding transport ABC transporter protein from Ralstonia solancearum (614 aa). FASTA: opt: 752 Z-score: 802.5 E(): 8.3e-37 Smith-Waterman score: 752; 29.020 identity in 510 aa overlap. Contains a frameshift after aa 322 and an in-frame stop codon after aa 140
393115004758	Amino acid permease; Region: AA_permease_2; pfam13520
393115004759	Obg family GTPase CgtA; Region: Obg_CgtA; TIGR02729
393115004760	GTP1/OBG; Region: GTP1_OBG; pfam01018
393115004761	Obg GTPase; Region: Obg; cd01898
393115004762	G1 box; other site
393115004763	GTP/Mg2+ binding site [chemical binding]; other site
393115004764	Switch I region; other site
393115004765	G2 box; other site
393115004766	G3 box; other site
393115004767	Switch II region; other site
393115004768	G4 box; other site
393115004769	G5 box; other site
393115004770	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
393115004771	aromatic amino acid transport protein; Region: araaP; TIGR00837
393115004772	Similar to Q47938 Outer membrane protein from Francisella tularensis (336 aa). FASTA: opt: 516 Z-score: 592.2 E(): 3.9e-25 Smith-Waterman score: 516; 41.589 identity in 214 aa overlap. Contains an in-frame stop codon after aa 71 and truncation at C-terminal according to FASTA hits No transmembrane helix predicted.
393115004773	Similar to Q8EKN3 Transcriptional regulatory protein KdpE (229 aa) FASTA: initn: 561 init1: 517 opt: 604 Z-score: 717.3 bits: 139.9 E(): 4.6e-32 Smith-Waterman score: 604; 41.704 identity (42.66139ngapped) in 223 aa overlap. (Part of two-component regulatory system). Contains a frameshift after aa 14 and an in-frame stop codon after aa 110. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift
393115004774	Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205
393115004775	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
393115004776	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
393115004777	Ligand Binding Site [chemical binding]; other site
393115004778	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
393115004779	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
393115004780	dimer interface [polypeptide binding]; other site
393115004781	phosphorylation site [posttranslational modification]
393115004782	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
393115004783	ATP binding site [chemical binding]; other site
393115004784	Mg2+ binding site [ion binding]; other site
393115004785	G-X-G motif; other site
393115004786	K+-transporting ATPase, c chain; Region: KdpC; cl00944
393115004787	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
393115004788	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
393115004789	Soluble P-type ATPase [General function prediction only]; Region: COG4087
393115004790	Similar to Q98GX5 Potassium-transporting ATPase, A chain, from (567 aa) FASTA: opt: 1342 Z-score: 1546.7 E(): 2.6e-78 Smith-Waterman score: 1401; 42.707 identity in 569 aa overlap. Contains numerous in-frame stop codons and a frameshift after aa 112
393115004791	No start codon ORF ftt1740c
393115004792	Similar to Q9F7P9 Predicted NAD-dependent formate dehydrenase from Gamma-proteobacterium EBAC31A08 (398 aa). FASTA: opt: 740 Z-score: 987.4 E(): 4.2e-47 Smith-Waterman score: 740; 72.464 identity in 138 aa overlap. This CDS has no start codon due to truncation at N-terminal by the insertion of an ISFtu1 element ORF ftt1741c
393115004793	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004794	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004795	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004796	Similar to AAO91087 (Q9CNR2) Monovalent cation/proton antiporter from Bos indicus (417 aa). FASTA:opt: 323 Z-score: 405.5 E(): 9.8e-15 Smith-Waterman score: 323; 36.424 identity in 151 aa overlap. This CDS lacks a start codon due to an interruption of an ISFtu1 element at the N-terminal end and is truncated at the C-terminal according to FASTA hits ORF ftt1743
393115004797	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
393115004798	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
393115004799	dimer interface [polypeptide binding]; other site
393115004800	PYR/PP interface [polypeptide binding]; other site
393115004801	TPP binding site [chemical binding]; other site
393115004802	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
393115004803	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
393115004804	TPP-binding site [chemical binding]; other site
393115004805	dimer interface [polypeptide binding]; other site
393115004806	Similar to P73195 Hypothetical protein sll1584 from Synechocystis sp (strain PCC 6803)(134 aa). FASTA: opt: 238 Z-score: 356.0 E(): 6.1e-12 Smith-Waterman score: 238; 51.471identity in 68 aa overlap. Truncation at C-terminal according to FASTA hits ORF ftt1745c
393115004807	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
393115004808	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
393115004809	tandem repeat interface [polypeptide binding]; other site
393115004810	oligomer interface [polypeptide binding]; other site
393115004811	active site residues [active]
393115004812	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
393115004813	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
393115004814	preprotein translocase subunit SecB; Provisional; Region: PRK13031
393115004815	SecA binding site; other site
393115004816	Preprotein binding site; other site
393115004817	recombinase A; Provisional; Region: recA; PRK09354
393115004818	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
393115004819	hexamer interface [polypeptide binding]; other site
393115004820	Walker A motif; other site
393115004821	ATP binding site [chemical binding]; other site
393115004822	Walker B motif; other site
393115004823	recombination regulator RecX; Reviewed; Region: recX; PRK00117
393115004824	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
393115004825	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
393115004826	dimer interface [polypeptide binding]; other site
393115004827	ssDNA binding site [nucleotide binding]; other site
393115004828	tetramer (dimer of dimers) interface [polypeptide binding]; other site
393115004829	propionate/acetate kinase; Provisional; Region: PRK12379
393115004830	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
393115004831	phosphate acetyltransferase; Reviewed; Region: PRK05632
393115004832	DRTGG domain; Region: DRTGG; pfam07085
393115004833	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
393115004834	Similar to Q9SEK4 Succinic semialdehyde dehydrogenase from Arabidopsis thaliana (528 aa). FASTA: opt: 938 bits: 211.9 E(): 3e-53 Smith-Waterman score: 938; 53.381 identity in a 281 aa overlap. Contains a frameshift after aa 225. This CDS is also disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end.
393115004835	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004836	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004837	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004838	Similar to AAO91543 (Q83A52) Major facilitator family transporter from Coxiella burnetii (443 aa). FASTA: opt: 1009 Z-score: 1114.6 E(): 3.1e-54 Smith-Waterman score: 1009; 40.394 identity in 406 aa overlap. Contains a frameshift after aa 72 and an in-frame stop codon after aa 181. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift ORF ftt1757c
393115004839	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
393115004840	Similar to P95483 Oxidase-related protein from Thermotoga maritima (321 aa). FASTA: opt: 358 Z-score: 431.0 E(): 3.7e-16 Smith-Waterman score: 527; 31.731 identity in 312 aa overlap. Contains a frameshift after aa 130 ORF ftt1759c
393115004841	pH-dependent sodium/proton antiporter; Provisional; Region: nhaA; PRK14854
393115004842	hypothetical protein; Provisional; Region: PRK05421
393115004843	putative catalytic site [active]
393115004844	putative metal binding site [ion binding]; other site
393115004845	putative phosphate binding site [ion binding]; other site
393115004846	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
393115004847	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
393115004848	putative acyl-acceptor binding pocket; other site
393115004849	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
393115004850	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
393115004851	putative acyl-acceptor binding pocket; other site
393115004852	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
393115004853	4Fe-4S binding domain; Region: Fer4; cl02805
393115004854	Domain of unknown function (DUF3470); Region: DUF3470; pfam11953
393115004855	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
393115004856	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
393115004857	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
393115004858	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
393115004859	ATP-grasp domain; Region: ATP-grasp; pfam02222
393115004860	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
393115004861	active site
393115004862	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
393115004863	Clp amino terminal domain; Region: Clp_N; pfam02861
393115004864	Clp amino terminal domain; Region: Clp_N; pfam02861
393115004865	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115004866	Walker A motif; other site
393115004867	ATP binding site [chemical binding]; other site
393115004868	Walker B motif; other site
393115004869	arginine finger; other site
393115004870	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
393115004871	Walker A motif; other site
393115004872	ATP binding site [chemical binding]; other site
393115004873	Walker B motif; other site
393115004874	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
393115004875	Similar to Q9CK00 Hypothetical protein PM1838 from Pasteurella multocida (234 aa). FASTA: opt: 390 Z-score: 473.8 E(): 1.5e-18 Smith-Waterman score: 390; 29.583 identity in 240 aa overlap. Contains an in-frame stop codon after aa 114 ORF ftt1770
393115004876	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
393115004877	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
393115004878	substrate binding site [chemical binding]; other site
393115004879	active site
393115004880	catalytic residues [active]
393115004881	heterodimer interface [polypeptide binding]; other site
393115004882	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
393115004883	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
393115004884	pyridoxal 5'-phosphate binding site [chemical binding]; other site
393115004885	catalytic residue [active]
393115004886	Similar to Q8RH52 Thermostable carboxypeptidase 1 (496 aa) FASTA: opt: 1208 Z-score: 1432.3 E(): 6.9e-72 Smith-Waterman score: 1208; 51.734 identity in 346 aa overlap. Truncated at N-terminal and has no start codon. ORF ftt1774c
393115004887	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
393115004888	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
393115004889	Cl- selectivity filter; other site
393115004890	Cl- binding residues [ion binding]; other site
393115004891	pore gating glutamate residue; other site
393115004892	dimer interface [polypeptide binding]; other site
393115004893	H+/Cl- coupling transport residue; other site
393115004894	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
393115004895	Protein of unknown function (DUF3568); Region: DUF3568; pfam12092
393115004896	Protein of unknown function (DUF3568); Region: DUF3568; pfam12092
393115004897	Protein of unknown function (DUF3568); Region: DUF3568; pfam12092
393115004898	Similar to AAO91223 (Q83AZ7) Membrane protein,putative, from Coxiella burnetii (205 aa). FASTA: opt: 303 Z-score: 367.4 E(): 1.3e-12 Smith-Waterman score: 303; 29.299identity in 157 aa overlap. Contains a frameshift after aa 149. This CDS is disrupted by the insertion of an ISFtu1 element occurring near the C-terminal end. ORF ftt1779
393115004899	Transposase; Region: HTH_Tnp_IS630; pfam01710
393115004900	DDE superfamily endonuclease; Region: DDE_3; pfam13358
393115004901	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
393115004902	Methyltransferase domain; Region: Methyltransf_31; pfam13847
393115004903	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
393115004904	S-adenosylmethionine binding site [chemical binding]; other site
393115004905	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
393115004906	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
393115004907	Walker A/P-loop; other site
393115004908	ATP binding site [chemical binding]; other site
393115004909	Q-loop/lid; other site
393115004910	ABC transporter signature motif; other site
393115004911	Walker B; other site
393115004912	D-loop; other site
393115004913	H-loop/switch region; other site
393115004914	ABC transporter; Region: ABC_tran_2; pfam12848
393115004915	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
393115004916	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
393115004917	metabolite-proton symporter; Region: 2A0106; TIGR00883
393115004918	putative substrate translocation pore; other site
393115004919	Similar to O86705 Hypothetical protein SCO6523 from Streptomyces coelicolour (346 aa). FASTA: opt: 659 Z-score: 775.4 E(): 2.5e-35 Smith-Waterman score: 659; 37.262 identity in 263 aa overlap. Contains a frameshift after aa 165. Truncation at N-terminus according to FASTA hits ORF ftt1786
393115004920	LysE type translocator; Region: LysE; cl00565
393115004921	Similar to ICIA_VIBCH (Q9KUN3) Chromosome initiation inhibitor from Vibrio choleraea (298 aa). FASTA: opt: 628 Z-score: 730.4 E(): 7.8e-33 Smith-Waterman score: 628; 38.000identity in 300 aa overlap. Contains a frameshift after aa 83. Frameshift occurs at a heptanucleotide sequence and so could be part of a programmed translational frameshift
393115004922	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
393115004923	Similar to Q8H0S9 Putative aminopeptidase from Aribdopsis thaliana (883 aa). FASTA: opt: 185 Z-score: 275.4 E(): 1.9e-07 Smith-Waterman score: 185; 53.571 identity in 56 aa overlap. Contains an in-frame stop codon after aa 61. Truncation at both N- and C-terminals according to FAST hits ORF ftt1790c
393115004924	Similar to Q9ZIX7, putative transposase from Haemophilus gallinarum (216 aa). FASTA: opt: 566 Z-score: 710.4 E(): 1e-31 Smith-Waterman score: 566; 42.056 identity in 214 aa overlap. Stop codon at aa position 99 Identical to FTF1053c. This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. ORF ftt1792c
393115004925	aminopeptidase N; Provisional; Region: pepN; PRK14015
393115004926	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
393115004927	active site
393115004928	Zn binding site [ion binding]; other site
393115004929	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
393115004930	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
393115004931	putative dimer interface [polypeptide binding]; other site
393115004932	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
393115004933	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
393115004934	active site
393115004935	ribulose/triose binding site [chemical binding]; other site
393115004936	phosphate binding site [ion binding]; other site
393115004937	substrate (anthranilate) binding pocket [chemical binding]; other site
393115004938	product (indole) binding pocket [chemical binding]; other site
393115004939	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
393115004940	active site
393115004941	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
393115004942	Peptide methionine sulfoxide reductase; Region: PMSR; pfam01625
393115004943	NHLP leader peptide domain; Region: TOMM_pelo; TIGR03793
393115004944	Similar to Q8YVF1 Hypothetical protein All2027 from Anabaena sp. (111 aa). FASTA: opt: 132 Z-score: 181.3 E(): 0.03 Smith-Waterman score: 132; 31.034 identity in 87 aa overlap. Contains an in-frame stop codon after aa 48 ORF ftt1799c
393115004945	Similar to Q8FHV8 Anthranilate synthase component II from E. coli (531 aa). FASTA: opt: 1761 Z-score: 1951.1 E(): 8e-101 Smith-Waterman score: 1761; 49.808 identity in 522 aa overlap. Contains frameshift after aa 192 unknown EC_number 4.3.1.27
393115004946	anthranilate synthase component I; Provisional; Region: PRK13564
393115004947	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
393115004948	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
393115004949	Trp repressor protein; Region: Trp_repressor; cl17266
393115004950	ribonuclease G; Provisional; Region: PRK11712
393115004951	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
393115004952	homodimer interface [polypeptide binding]; other site
393115004953	oligonucleotide binding site [chemical binding]; other site