-- dump date 20140619_095532 -- class Genbank::CDS -- table cds_note -- id note YP_169084.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_169085.1 Similar to DP3B_ECOLI (P00583) DNA polymerase III, beta chain from E. coli (366 aa). FASTA opt: 826 Z-score: 955.1 E(): 2.6e-45 Smith-Waterman score: 826; 35.230 identity in 369 aa overlap YP_169086.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169087.1 Similar to Q9ZE69 Proline/betaine transporter (PROP1) from Rickettsia prowazekii (418 aa). FASTA: opt: 605 Z-score: 665.8 E(): 3.4e-29 Smith-Waterman score: 605; 28.293 identity in 410 aa overlap ORF ftt0006 YP_169088.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_169089.1 ORF ftt0013c YP_169090.1 ORF ftt0014c YP_169091.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_169092.1 ORF ftt0016 YP_169093.1 Similar to Q8PAK3 Toxin secretion ABC transporter ATP-binding protein from Xanthomonas axonopodis (563 aa). FASTA: opt: 454 Z-score: 516.4 E(): 7.1e-21 Smith-Waterman score: 454; 24.395identity in 496 aa overlap ORF ftt0017 YP_169094.1 Similar to Q8PMA5 RND efflux membrane fusion protein from Xanthomonas axonopodis (354 aa). FASTA: opt: 851 Z-score: 971.0 E(): 3.4e-46 Smith-Waterman score: 851; 37.846 identity in 325 aa overlap ORF ftt0018 YP_169095.1 Similar to Q82T57 Glu-tRNAGln amidotransferase C subunit from Nitrosomonas europaea (95 aa). FASTA:i opt: 188 Z-score: 259.9 E(): 1.4e-06 Smith-Waterman score: 188; 31.818 identity in 88 aa overlap YP_169096.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_169097.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_169098.1 ORF ftt0022 YP_169101.1 ORF ftt0025c YP_169102.1 Similar to Q9HWP5 Probable MFS transporter from Pseudomonas aeruginosa (402 aa). FASTA: opt: 568 Z-score: 586.0 E(): 9.5e-25 Smith-Waterman score: 568; 26.425 identity in 386 aa overlap ORF ftt0026c YP_169103.1 Similar to DCDA_BACSU (P23630) Diaminopimelate decarboxylase from Bacillus subtilis (441 aa). FASTA: opt: 437 Z-score: 538.0 E(): 4.5e-22 Smith-Waterman score: 437; 27.295 identity in 414 aa overlap YP_169104.1 Similar to YCEE_ECOLI (P25744) Hypothetical transport protein yce from E. coli (408 aa). FASTA: opt: 364 Z-score: 408.7 E(): 7.1e-15 Smith-Waterman score: 450; 26.582 identity in 395 aa overlap ORF ftt0028c YP_169105.1 Similar to AAO89973 (Q83EA5) FrgA protein from Coxiella burnetii (528 aa). FASTA: opt: 1047 Z-score: 1237.4 E(): 4.9e-61 Smith-Waterman score: 1053; 34.051 identity in 511 aa overlap ORF ftt0029c YP_169106.1 Similar to FUR_ECOLI (P06975) Ferric uptake regulation protein from E. coli (148 aa). FASTA: opt: 396 Z-score: 515.7 E(): 7.8e-21 Smith-Waterman score: 396; 40.714 identity in 140 aa overlap YP_169107.1 Similar to Q9A6X0 NADH dehydrogenase I, A subunit from Caulobacter crescentus (125 aa). FASTA: opt: 398 Z-score: 508.1 E(): 2.1e-20 Smith-Waterman score: 398; 46.565 identity in 131 aa overlap YP_169108.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_169109.1 Similar to NUOC_NEIMB (Q9K1C1) NADH-quinone oxidoreductase chain from Neisseria meningitidis (197 aa). FASTA: opt: 516 Z-score: 659.3 E(): 7.8e-29 Smith-Waterman score: 568; 44.286identity in 210 aa overlap YP_169110.1 Catalyzes the transfer of electrons from NADH to quinone YP_169111.1 Similar to Q83BQ9 NADH dehydrogenase I, E subunit from Xanthomonas campestris (174 aa). FASTA: opt: 528 Z-score: 689.7 E(): 1.6e-30 Smith-Waterman score: 528; 52.318 identity in 151 aa overlap YP_169112.1 Similar to Q83BR0 NADH dehydrogenase I, F subunit from Coxiella burnetti (422 aa). FASTA: opt: 1851 Z-score: 2306.0 E(): 1.5e-120 Smith-Waterman score: 1851; 61.848 identity in 422 aa overlap YP_169113.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_169114.1 Similar to Q83BR2 NADH dehydrogenase I, H subunit from Coxiella burnetii (340 aa). FASTA: opt: 1510 Z-score: 1695.3 E(): 1.5e-86 Smith-Waterman score: 1510; 60.843 identity in 332 aa overlap YP_169115.1 Catalyzes the transfer of electrons from NADH to quinone YP_169116.1 Similar to Q9K1B2 NADH dehydrogenase I, J subunit from Neisseria meningitidis (223 aa). FASTA: opt: 387 Z-score: 452.6 E(): 2.6e-17 Smith-Waterman score: 387; 38.191 identity in 199 aa overlap YP_169117.1 Similar to Q9A6Y6 NADH dehydrogenase I, K subunit from Caulobacter crescentus (101 aa). FASTA: opt: 300 Z-score: 405.7 E(): 1e-14 Smith-Waterman score: 300; 43.000 identity in 100 aa overlap YP_169118.1 Similar to Q83BR6 NADH dehydrogenase I, L subunit from Coxiella burnetii (653 aa). FASTA: opt: 1934 Z-score: 2065.6 E(): 3.6e-107 Smith-Waterman score: 2090; 50.760 identity in 658 aa overlap YP_169119.1 Similar to Q83BR7 NADH dehydrogenase I, M subunit from Coxiella burnetii (506 aa). FASTA: opt: 1099 Z-score: 1147.9 E(): 4.8e-56 Smith-Waterman score: 1659; 47.228 identity in 523 aa overlap YP_169120.1 Similar to Q83BR8 NADH dehydrogenase I, N subunit from Coxiella burnetii (482 aa). FASTA: opt: 1231 Z-score: 1222.9 E(): 3.2e-60 Smith-Waterman score: 1231; 39.914 identity in 466 aa overlap YP_169121.1 Similar to Q8DDC7 Conserved hypothetical protein from Vibrio vulnificus (83 aa). FASTA: opt: 165 Z-score: 224.7 E(): 0.00013 Smith-Waterman score: 165; 45.763 identity in 59 aa overlap ORF ftt0045 YP_169122.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_169123.1 Similar to Q88DV5 Conserved hypothetical protein from Pseudomonas putida (169 aa). FASTA: opt: 402 Z-score: 490.7 E(): 1.7e-19 Smith-Waterman score: 402; 43.243 identity in 148 aa overlap ORF ftt0048 YP_169124.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_169125.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_169126.1 Similar to RBFA_ECOLI (P09170) Ribosome-binding factor A from E. coli (132 aa). FASTA: opt: 301 Z-score: 381.1 E(): 2.5e-13 Smith-Waterman score: 301; 41.935 identity in 124 aa overlap YP_169127.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_169128.1 Similar to AAO90449 (Q83D24) Major facilitator family transporter from Coxiella burnetii (437 aa). FASTA: opt: 908 Z-score: 1023.7 E(): 3.6e-49 Smith-Waterman score: 909; 36.603 identity in 418 aa overlap ORF ftt0053 YP_169129.1 Similar to YHCM_ECOLI (P46442) Hypothetical protein yhcM from E. coli (375 aa). FASTA: opt: 872 Z-score: 1033.2 E(): 1.2e-49 Smith-Waterman score: 898; 39.833 identity in 359 aa overlap ORF ftt0054 YP_169130.1 Similar to RLUC_ECOLI (P23851) Ribosomal large subunit pseudouridine synthase C from E. coli (319 aa). FASTA: opt: 791 Z-score: 972.5 E(): 2.8e-46 Smith-Waterman score: 791; 40.777 identity in 309 aa overlap YP_169131.1 Similar to Q83D24 (Q83D24) Major facilitator family transporter from Coxiella burnetii (437 aa). FASTA: opt: 1028 Z-score: 1172.6 E(): 2e-57 Smith-Waterman score: 1036; 40.187 identity in 428 aa overlap ORF ftt0056c YP_169132.1 ORF ftt0057 YP_169133.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_169134.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0 YP_169135.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_169136.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_169137.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_169138.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the gamma chain is a regulatory subunit YP_169139.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_169140.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex YP_169141.1 ORF ftt0066 YP_169142.1 Similar to Q8D879 Glutaredoxin-related protein from Vibrio vulnificus (112 aa). FASTA: opt: 485 Z-score: 630.6 E(): 2.8e-27 Smith-Waterman score: 485; 65.306 identity in 98 aa overlap ORF ftt0067c YP_169143.1 Similar to SODF_ECOLI (P09157) Superoxide dismutase [Fe] from E. coli (192 aa). FASTA: opt: 896 Z-score: 1143.2 E(): 8.8e-56 Smith-Waterman score: 896; 66.316 identity in 190 aa overlap YP_169144.1 ORF ftt0069c YP_169145.1 Similar to AMPG_ECOLI (P36670) AmpG protein from E. coli (491 aa). FASTA: opt: 996 Z-score: 1121.1 E(): 1.5e-54 Smith-Waterman score: 996; 38.614 identity in 404 aa overlap YP_169146.1 Similar to CISY_PSEAE (P14165) Citrate synthase from Pseudomonas aeruginosa (428 aa). FASTA: opt: 1540 Z-score: 1956.3 E(): 4.5e-101 Smith-Waterman score: 1540; 57.353 identity in 408 aa overlap YP_169147.1 Similar to Q884A1 Succinate dehydrogenase, cytochrome b556 subunit from Pseudomonas syringae (124 aa). FASTA: opt: 332 Z-score: 413.6 E(): 3.8e-15 Smith-Waterman score: 332; 39.844identity in 128 aa overlap YP_169148.1 Similar to Q88FA6 Succinate dehydrogenase, hydrophobic membrane anchor protein from Pseudomonas putida (122 aa). FASTA: opt: 242 Z-score: 306.8 E(): 3.4e-09 Smith-Waterman score: 242; 34.677 identity in 124 aa overlap YP_169149.1 Similar to Q9I3D5 Succinate dehydrogenase (A subunit) from Pseudomonas aeruginosa (590 aa). FASTA: opt: 2468 Z-score: 2874.7 E(): 3.2e-152 Smith-Waterman score: 2468; 61.139 identity in 597 aa overlap YP_169150.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_169151.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_169152.1 Similar to Q8EFN9 2-oxoglutarate dehydrogenase,E2 component, dihydrolipoamide succinyltransferase from Shewanella oneidensis (395 aa). FASTA: opt: 1379 Z-score: 1563.0 E(): 3.6e-79 Smith-Waterman score: 1379; 55.949 identity in 395 aa overlap YP_169153.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_169154.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_169155.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_169156.1 Similar to Q9KU83 Preprotein translocase, SecG subunit from Vibrio cholerae (111 aa). FASTA: opt: 283 Z-score: 369.6 E(): 1.1e-12 Smith-Waterman score: 289; 45.299identity in 117 aa overlap. Together with SecE and SecY forming an integral membrane complex. YP_169157.1 ORF ftt0083 YP_169158.1 Similar to Q87V87 Oxygen-independent coproporphyrinogen III oxidase,,from Pseudomonas syringae (404 aa). FASTA: opt: 1156 Z-score: 1386.6 E(): 2.4e-69 Smith-Waterman score: 1156; 46.791 identity in 374 aa overlap YP_169159.1 Similar to YWCD_BACSU P39602 Hypothetical protein ywcD from Bacillus subtilis (127 aa). FASTA: opt: 162 Z-score: 223.9 E(): 0.00013 Smith-Waterman score: 162; 26.667 identity in 120 aa overlap ORF ftt0085c YP_169160.1 Similar to Q9I078 Hypothetical protein PA2765 from Pseudomonas aeruginosa (299 aa). FASTA: opt: 656 Z-score: 793.3 E(): 2.4e-36 Smith-Waterman score: 656; 36.678 identity in 289 aa overlap ORF ftt0086 YP_169161.1 Catalyzes the conversion of citrate to isocitrate YP_169162.1 Similar to Q8EBZ4 Twitching motility protein PilT from Shewanella oneidensis (345 aa). FASTA: opt: 1226 Z-score: 1391.3 E(): 1.3e-69 Smith-Waterman score: 1226; 57.186 identity in 334 aa overlap Required for pili retraction probably by filament disassembly. Homologous to pilB but which has the opposite effect. Unique to type IV pili. YP_169163.1 Similar to Q87GR3 Hypothetical protein from Vibrio parahaemolyticus (148 aa). FASTA: opt: 160 Z-score: 212.3 E(): 0.00057 Smith-Waterman score: 160; 29.104 identity in 134 aa overlap ORF ftt0090c YP_169164.1 Similar to Q87H27 Cytochrome BD2, subunit II from Vibrio parahaemolyticus (335 aa). FASTA: opt: 573 Z-score: 669.5 E(): 1.9e-29 Smith-Waterman score: 750; 34.743 identity in 331 aa overlap YP_169165.1 Similar to Q8FFI5 Hypothetical protein yfcH from E. coli (297 aa). FASTA: opt: 498 Z-score: 611.0 E(): 3.8e-26 Smith-Waterman score: 498; 32.673 identity in 303 aa overlap ORF ftt0093 YP_169166.1 Similar to AAO90737 (Q83CA0) Sensor histidine kinase from Coxiella burnetii (478 aa). FASTA: opt: 653 Z-score: 752.8 E(): 4.9e-34 Smith-Waterman score: 677; 29.083 identity in 447 aa overlap Sensory histidine kinase in two-component regulatory system with QseB, regulates flagella and motility by quorum sensing in E. coli, according to Q8X524 YP_169167.1 ORF ftt0095 YP_169168.1 ORF ftt0096 YP_169169.1 ORF ftt0097 YP_169170.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169171.1 ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 transposase from Francisella tularensis (247 aa). YP_169172.1 Similar to Y402_RICPR (Q9ZDC9) Hypothetical protein RP402 from Rickettsia prowazekii (317 aa). FASTA: opt: 431 Z-score: 518.0 E(): 5.9e-21 Smith-Waterman score: 432; 28.909 identity in 339 aa overlap ORF ftt0101 YP_169173.1 ORF ftt0103c YP_169174.1 Similar to Q83DX6 Major facilitator family transporter from Coxiella burnetii (421 aa). FASTA: opt: 995 Z-score: 1049.4 E(): 1.5e-50 Smith-Waterman score: 995; 39.066identity in 407 aa overlap ORF ftt0104c YP_169175.1 Similar to AAO90606 (Q83CM1) Transporter,AcrB/AcrD/AcrF family from Coxiella burnetii (1019 aa). FASTA: opt: 2662 Z-score: 2840.6 E(): 2.3e-150 Smith-Waterman score: 3071; 45.171identity in 1025 aa overlap ORF ftt0105c YP_169176.1 Similar to Q83CM0 Efflux transporter, RND family, MFP subunit from Coxiella burnetti (380 aa). FASTA: opt: 732 Z-score: 824.0 E(): 5.2e-38 Smith-Waterman score: 781; 34.748identity in 377 aa overlap ORF ftt0106c YP_169177.1 Similar to DSBB_NEIMB (Q9JYC6) Disulfide bond formation protein B (disuphide oxidoreductase) from Neisseria meningitidis (162 aa). FASTA: opt: 171 Z-score: 223.1 E(): 0.00014 Smith-Waterman score: 171; 27.344 identity in 128 aa overlap YP_169178.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity YP_169179.1 lipid A transport protein, ABC transporter,ATP-binding and membrane protein. Similar to Q47908 ValA from Francisella novicida strain U112 (572 aa). FASTA: opt: 3334 Z-score: 3684.8 E(): 2.4e-197 Smith-Waterman score: 3334; 97.810 identity in 548 aa overlap (54-601:13-559). Similar to MSBA_HAEIN (P44407) Lipid A export ATP-binding protein from Haemophilus influenzae (587 aa). FASTA: opt: 1570 Z-score: 1735.1 E(): 9.4e-89 Smith-Waterman score: 1570; 41.913identity in 575 aa overlap. YP_169180.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_169181.1 Similar to AAO91288 (Q83AT5) DNA polymerase I from Coxiella burnetii (895 aa). FASTA: opt: 2961 Z-score: 3329.8 E(): 1.4e-177 Smith-Waterman score: 2961; 52.058 identity in 899 aa overlap YP_169182.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_169183.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_169184.1 Similar to AAP95774 (Q7VMS9) Deoxyribose-phosphate aldolase from Haemophilus ducreyi (258 aa). FASTA: opt: 632 Z-score: 764.1 E(): 1.1e-34 Smith-Waterman score: 632; 42.857 identity in 245 aa overlap YP_169185.1 Similar to AAP07626 (Q81I17) Nucleoside permease nupC from Bacillus cereus (392 aa). FASTA: opt: 1236 Z-score: 1430.7 E(): 7.7e-72 Smith-Waterman score: 1236; 49.246 identity in 398 aa overlap Paralog of FTT0116 YP_169186.1 Similar to (AAP07626) Q81I17 Nucleoside permease nupC from Bacillus cereus (392 aa). FASTA: opt: 1351 Z-score: 1549.9 E(): 1.9e-78 Smith-Waterman score: 1351; 52.381 identity in 399 aa overlap Paralog of FTT0115 YP_169187.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_169188.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_169189.1 ORF ftt0119 YP_169190.1 Similar to Q9I6C1 Signal recognition particle receptor FtsY from Pseudomonas aeruginosa (455 aa). FASTA: opt: 1262 Z-score: 1403.4 E(): 2.8e-70 Smith-Waterman score: 1262; 61.935identity in 310 aa overlap YP_169191.1 Similar to Q88C31 DNA helicase II from Pseudomonas putida (728 aa). FASTA: opt: 1880 Z-score: 2129.9 E(): 9.6e-111 Smith-Waterman score: 2083; 45.867 identity in 750 aa overlap YP_169192.1 Similar to Q8D8A2 Oligopeptide ABC transporter,ATP-binding protein D from Vibrio vulnificus (324 aa). FASTA: opt: 1202 Z-score: 1353.8 E(): 1.6e-67 Smith-Waterman score: 1202; 56.270 identity in 311 aa overlap YP_169193.1 Similar to OPPF_HAEIN (P45051) Oligopeptide transport ATP-binding oppF from Haemophilus influenzae (332 aa). FASTA: opt: 1227 Z-score: 1398.5 E(): 5.3e-70 Smith-Waterman score: 1227; 56.790 identity in 324 aa overlap YP_169194.1 Similar to Q83CF6 Major facilitator family transporter from Coxiella burnetii (443 aa). FASTA: opt: 488 Z-score: 542.0 E(): 2.7e-22 Smith-Waterman score: 490; 27.621identity in 391 aa overlap ORF ftt0127c YP_169195.1 ORF ftt0128 YP_169196.1 Similar to Q83BM0 (Q83BM0) Major facilitator family transporter from Coxiella burnetii (428 aa). FASTA: opt: 497 Z-score: 533.3 E(): 8.2e-22 Smith-Waterman score: 529; 26.355 identity in 406 aa overlap ORF ftt0129 YP_169197.1 Similar to GLPK_THETN (Q8R8J4) Glycerol kinase from Thermoanaerobacter tengcongensis (497 aa). FASTA: opt: 2233 Z-score: 2691.0 E(): 5.3e-142 Smith-Waterman score: 2233; 66.333 identity in 499 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein YP_169198.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169199.1 Similar to O51259 Glycerol-3-phosphate dehydrogenase, anaerobic, from Borrelia burgdorferii (527 aa). FASTA: opt: 1330 Z-score: 1506.9 E(): 4.8e-76 Smith-Waterman score: 1330; 43.333 identity in 510 aa overlap YP_169200.1 Similar to CAD75967 (Q7UMF0) Probable glycerol uptake facilitator protein from Rhodopirelulla baltica (271 aa). FASTA: opt: 796 Z-score: 888.1 E(): 1.4e-41 Smith-Waterman score: 796; 50.209 identity in 239 aa overlap YP_169201.1 ORF ftt0134 YP_169202.1 Similar to AAQ00172 (Q7VBG7) DNA helicase related to phage enzyme from Prochlorococcus marinus (479 aa) FASTA: opt: 386 Z-score: 446.1 E(): 5.9e-17 Smith-Waterman score: 386; 26.681 identity in 476 aa overlap ORF ftt0136 YP_169203.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_169204.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_169205.1 Similar to NUSG_VIBVU (Q8DD25) Transcription antitermination protein nusG from Vibrio vulnificus (181 aa). FASTA: opt: 687 Z-score: 868.9 E(): 1.7e-40 Smith-Waterman score: 687; 58.621 identity in 174 aa overlap YP_169206.1 binds directly to 23S ribosomal RNA YP_169207.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_169208.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_169209.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_169210.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_169211.1 Similar to Q9AAU1 (Q9AAU1) DNA-directed RNA polymerase, beta subunit from Caulobacter crescentus (1396 aa). FASTA: opt: 5089 Z-score: 5550.7 E(): 0 Smith-Waterman score: 5089; 56.626identity in 1381 aa overlap YP_169212.1 ORF ftt0146 YP_169213.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_169214.1 Similar to Q27437 Stearoyl-CoA desaturase from Amblyomma americanum (317 aa). FASTA: opt: 653 Z-score: 747.5 E(): 9.6e-34 Smith-Waterman score: 653; 36.897 identity in 290 aa overlap ORF ftt0148 YP_169215.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_169216.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_169217.1 Essential for efficient processing of 16S rRNA YP_169218.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_169219.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_169220.1 Similar to Q7ZAJ8 (Q7ZAJ8) Integrase/recombinase XerD from Shewanella oneidensis (300 aa). FASTA: opt: 1039 Z-score: 1285.0 E(): 1.1e-63 Smith-Waterman score: 1039; 52.414 identity in 290 aa overlap YP_169221.1 Similar to Q87HU0 oxidoreductase iron/ascorbate from Vibrio parahaemolyticus (279 aa). FASTA: opt: 944 Z-score: 1155.0 E(): 1.9e-56 Smith-Waterman score: 944; 49.110 identity in 281 aa overlap ORF ftt0155 YP_169222.1 Similar to Q83EI5 Acid phosphatase, class B from Coxiella burnetti (221 aa). FASTA: opt: 326 Z-score: 430.9 E(): 4.1e-16 Smith-Waterman score: 326; 32.642identity in 193 aa overlap ORF ftt0156 YP_169223.1 Similar to Q8XMR0 Probable lic-1 operon protein from Clostridium perfringens (322 aa). FASTA: opt: 370 Z-score: 410.4 E(): 5.7e-15 Smith-Waterman score: 396; 30.492 identity in 305 aa overlap ORF ftt0157c YP_169224.1 ORF ftt0158c YP_169225.1 ORF ftt0159c YP_169226.1 hydrolyzes diadenosine polyphosphate YP_169227.1 Similar to Q8FXE8 PAP2 family protein from Brucella suis (325 aa). FASTA: opt: 314 Z-score: 375.8 E(): 4.8e-13 Smith-Waterman score: 314; 31.915identity in 188 aa overlap ORF ftt0161c YP_169228.1 Similar to Q88PQ9 N-acetyl-anhydromuramyl-L-alanine amidase ampD from Pseudomonas putida (190 aa). FASTA: opt: 623 Z-score: 809.4 E(): 3.4e-37 Smith-Waterman score: 623; 52.000 identity in 175 aa overlap YP_169229.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_169230.1 Similar to Q9KRK6 Multidrug resistance protein from Vibrio cholerae (401 aa). FASTA: opt: 579 Z-score: 614.0 E(): 2.6e-26 Smith-Waterman score: 579; 28.989identity in 376 aa overlap ORF ftt0164c YP_169231.1 Similar to Q88PJ4 Conserved hypothetical protein from Pseudomonas putida (380 aa). FASTA: opt: 644 Z-score: 755.3 E(): 3.5e-34 Smith-Waterman score: 646; 29.268 identity in 369 aa overlap ORF ftt0165c YP_169232.1 Similar to Q8FF57 Hypothetical protein yfgM from E. coli (206 aa). FASTA: opt: 155 Z-score: 188.7 E(): 0.012 Smith-Waterman score: 188; 27.778 identity in 198 aa overlap ORF ftt0166c YP_169233.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_169234.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_169235.1 ORF ftt0169 YP_169236.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169237.1 Similar to Q83A22 Hypothetical protein from Coxiella burnetti (192 aa). FASTA: opt: 440 Z-score: 543.8 E(): 2.1e-22 Smith-Waterman score: 440; 37.634 identity in 186 aa overlap ORF ftt0174 YP_169238.1 Similar to AAO80856 (Q836Q5) ABC transporter, ATP-binding protein (269 aa). FASTA: opt: 738 Z-score: 809.5 E(): 3.1e-37 Smith-Waterman score: 738; 43.137 identity in 255 aa overlap missing 90 aa at C-terminus ORF ftt0175c YP_169239.1 Similar to Q88IP2 Acetyltransferase, GNAT family from Pseudomonas putida (364 aa). FASTA: opt: 250 Z-score: 324.7 E(): 3.1e-10 Smith-Waterman score: 250; 34.559 identity in 136 aa overlap ORF ftt0177c YP_169240.1 Similar to Q9KPN3 Ribosomal protein S6 modification protein-related protein from Vibrio cholerae (483 aa). FASTA: opt: 1367 Z-score: 1648.7 E(): 6.1e-84 Smith-Waterman score: 1367; 43.149 identity in 489 aa overlap YP_169241.1 Similar to Q8DDF5 1-acyl-sn-glycerol-3-phosphate acyltransferase from Vibrio vulnificus (271 aa). FASTA: opt: 749 Z-score: 902.5 E(): 2e-42 Smith-Waterman score: 749; 40.370 identity in 270 aa overlap ORF ftt0180 YP_169242.1 Similar to Q9X885 small integral membrane protein from Streptomyces coelicolor (167 aa). FASTA: opt: 262 Z-score: 342.1 E(): 3.6e-11 Smith-Waterman score: 262; 30.723 identity in 166 aa overlap ORF ftt0181c YP_169243.1 Similar to Q8D257 YrdC protein from Wigglesworthia glossinidia (194 aa). FASTA: opt: 374 Z-score: 473.0 E(): 1.9e-18 Smith-Waterman score: 374; 39.130 identity in 184 aa overlap ORF ftt0182c YP_169244.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_169245.1 Similar to Q83DS3 Zinc-binding domain protein from Coxiella burnetii (142 aa). FASTA: opt: 473 Z-score: 642.4 E(): 6.8e-28 Smith-Waterman score: 473; 52.817 identity in 142 aa overlap ORF ftt0184 YP_169246.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_169247.1 Similar to Q83F15 Cell division protein FtsQ from Coxiella burnetii (243 aa). FASTA: opt: 291 Z-score: 355.4 E(): 6.6e-12 Smith-Waterman score: 291; 23.176 identity in 233 aa overlap YP_169248.1 Similar to Q87WY9 Cell division protein FtsA from Pseuodomonas syringae (418 aa). FASTA: opt: 992 Z-score: 1194.6 E(): 1.2e-58 Smith-Waterman score: 992; 37.621 identity in 412 aa overlap YP_169249.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_169250.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_169251.1 Similar to Q8DB24 DNA polymerase III, gamma/tau subunits from Vibrio vulnificus (734 aa). FASTA: opt: 1193 Z-score: 1334.5 E(): 1.9e-66 Smith-Waterman score: 1193; 44.893 identity in 421 aa overlap YP_169252.1 Similar to RF2_HAEIN (P43918) Peptide chain release factor 2 from Haemophilus influenzae (365 aa). FASTA: opt: 1542 Z-score: 1839.9 E(): 1.4e-94 Smith-Waterman score: 1542; 68.405 identity in 326 aa overlap YP_169253.1 Similar to SYK2_ECOLI (P14825) Lysyl-tRNA synthetase, heat inducible, from E. coli (504 aa). FASTA: opt: 2003 Z-score: 2242.9 E(): 4.9e-117 Smith-Waterman score: 2003; 61.066 identity in 488 aa overlap YP_169254.1 Similar to Y208_VIBCH (Q9KVD8) Hypothetical protein VC0208 from Vibrio cholerae (162 aa). FASTA: opt: 414 Z-score: 528.5 E(): 1.5e-21 Smith-Waterman score: 414; 41.875 identity in 160 aa overlap ORF ftt0193c YP_169255.1 Similar to Q8X898 Hypothetical 31.1 kDa protein (Hypothetical membrane protein) from E.coli (274 aa). FASTA: opt: 398 Z-score: 431.1 E(): 4e-16 Smith-Waterman score: 398; 26.429 identity in 280 aa overlap ORF ftt0194c YP_169256.1 Similar to Q8IX91 L-glutaminase from Homo sapien (602 aa). FASTA: opt: 1441 Z-score: 1670.0 E(): 3.9e-85 Smith-Waterman score: 1441; 42.887 identity in 478 aa overlap ORF ftt0195c YP_169257.1 Similar to AAO90051 (Q83E31) Glutamine synthetase from Coxiella burnetti (359 aa). FASTA: opt: 1369 Z-score: 1705.1 E(): 4.4e-87 Smith-Waterman score: 1369; 59.226 identity in 336 aa overlap YP_169258.1 Similar to Q88DM9 DNA polymerase III, delta subunit from Pseudomonas putida (345 aa). FASTA: opt: 380 Z-score: 451.8 E(): 2.8e-17 Smith-Waterman score: 380; 28.707 identity in 317 aa overlap YP_169259.1 Similar to Q8EGB4 Lipoprotein Blc from Shewenella oneidensis (177 aa). FASTA: opt: 620 Z-score: 813.1 E(): 2.1e-37 Smith-Waterman score: 620; 56.604 identity in 159 aa overlap YP_169262.1 ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 transposase from Francisella tularensis (247 aa). YP_169263.1 involved in de novo purine biosynthesis YP_169264.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_169265.1 Similar to Q8R7L0 Hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcogenesis (181 aa). FASTA: opt: 509 Z-score: 658.7 E(): 8.5e-29 Smith-Waterman score: 509; 47.337 identity in 169 aa overlap YP_169266.1 Similar to Q8G5L3 Possible permease of ABC transporter system from Bifidobacterium longum (277 aa). FASTA: opt: 582 Z-score: 622.6 E(): 8.7e-27 Smith-Waterman score: 582; 38.372identity in 258 aa overlap ORF ftt0207c YP_169267.1 Similar to MNTB_BACSU (O34338) Manganese transport system ATP-binding protein mntB from Bacillus subtilis (250 aa). FASTA: opt: 365 Z-score: 426.7 E(): 7.1e-16 Smith-Waterman score: 365; 30.986 identity in 213 aa overlap ORF ftt0208c YP_169268.1 Similar to Q88TE8 ABC transporter substrate binding protein from Lactobacillus plantarum (297 aa). FASTA: opt: 555 Z-score: 628.8 E(): 3.9e-27 Smith-Waterman score: 555; 30.935identity in 278 aa overlap ORF ftt0209c YP_169269.1 Similar to Q9F6B1 Outer membrane lipoprotein Pcp from Edwardsiella tarda (155 aa). FASTA: opt: 294 Z-score: 329.0 E(): 2e-10 Smith-Waterman score: 294; 35.032 identity in 157 aa overlap ORF ftt0211c YP_169270.1 Similar to Q9I509 Trp repressor binding protein WrbA from Pseudomonas aeruginosa (198 aa). FASTA: opt: 727 Z-score: 948.0 E(): 6.5e-45 Smith-Waterman score: 727; 54.974 identity in 191 aa overlap YP_169271.1 Similar to RBN_ECOLI (P32146) tRNA processing ribonuclease BN from E. coli (290 aa). FASTA: opt: 535 Z-score: 578.5 E(): 2.5e-24 Smith-Waterman score: 535; 33.813 identity in 278 aa overlap YP_169272.1 Similar to Q9KNQ3 Primosomal protein N` from Vibrio cholerae (734 aa). FASTA: opt: 1587 Z-score: 1770.8 E(): 9.7e-91 Smith-Waterman score: 1619; 37.823 identity in 735 aa overlap YP_169273.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169274.1 Similar to Q81FW2 Low-affinity inorganic phosphate transport protein from Bacillus cereus (332 aa). FASTA: opt: 932 Z-score: 1065.7 E(): 1.8e-51 Smith-Waterman score: 932; 42.470 identity in 332 aa overlap ORF ftt0219c YP_169275.1 Similar to Q8XMV6 Hypothetical protein CPE0582 from Clostridium perfringens (210 aa). FASTA: opt: 207 Z-score: 248.6 E(): 5.9e-06 Smith-Waterman score: 207; 24.883 identity in 213 aa overlap ORF ftt0220c YP_169277.1 Similar to YBGK_HAEIN (P44298) Hypothetical protein HI1730 from Haemophilus influenzae (309 aa). FASTA: opt: 308 Z-score: 386.7 E(): 1.2e-13 Smith-Waterman score: 352; 32.453 identity in 265 aa overlap YP_169278.1 Similar to Y993_PYRAB (Q9V005) Hypothetical UPF0271 protein PYRAB09930 from Pyrococcus abyssi (255 aa). FASTA: opt: 430 Z-score: 541.0 E(): 3e-22 Smith-Waterman score: 430; 35.294 identity in 238 aa overlap YP_169279.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169280.1 ORF ftt0227c YP_169281.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_169282.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_169283.1 Similar to Q87B50 Type IV pilin from Xylella fastidiosa (142 aa). FASTA: opt: 224 Z-score: 300.3 E(): 7.8e-09 Smith-Waterman score: 224; 32.090 identity in 134 aa overlap The pili fiber building block protein has a highly distinct primary structure; a short positively charged leader sequence, and a highly conserved and highly hydrophobic amino-terminal domain which forms the core of the pilus fiber; A variety of studies suggest that the invariant glycine (G) at -1 is required for prepilin cleavage and assembly and that the glutamate (E) at + 5 is essential for assembly and efficient N-terminal methylation but not cleavage. The region near the carboxy terminus is often hydrophilic and is stabilized by one or two disulfide bridges that may be involved in recognition of receptors. The genes with these characteristics are usually termed pilA, pilE, pilV, pilW, pilX and FimU. (Mattick John S.. 'Type IV Pili and twitching motility'. Annu. Rev. Microbiol. 2002. 56:289-314.) This protein has all the characteristics described above. ORF ftt0230c YP_169284.1 Similar to HTRB_ECOLI (P24187) Lipid A biosynthesis lauroyl acyltransferase from E. coli (306 aa). FASTA: opt: 542 Z-score: 697.7 E(): 5.7e-31 Smith-Waterman score: 542; 32.895 identity in 304 aa overlap (8-307:14-306) n.b.Paralog of FTT0232c YP_169285.1 Similar to Q8ZNA3 (Q8ZNA3) Cold shock-induced palmitoleoyl transferase from Salmonella typhimurium (306 aa). FASTA: opt: 629 Z-score: 782.5 E(): 1.1e-35 Smith-Waterman score: 629; 36.755 identity in 302 aa overlap Paralog of FTT0231c YP_169286.1 Similar to 60IM_COXBU (P45650) 60 kDa inner-membrane protein homolog from Coxiella burnetti (566 aa). FASTA: opt: 1434 Z-score: 1537.8 E(): 8.4e-78 Smith-Waterman score: 1434; 41.815 identity in 562 aa overlap YP_169288.1 Similar to RNPA_VIBCH (Q9KVY2) Ribonuclease P protein component from Vibrio cholerae (118 aa). FASTA: opt: 189 Z-score: 256.8 E(): 2.1e-06 Smith-Waterman score: 189; 35.870 identity in 92 aa overlap YP_169289.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_169290.1 ORF ftt0237c YP_169291.1 Similar to AROE_VIBVU (Q8DDD4) Shikimate 5-dehydrogenase from Vibrio vulnificus (277 aa). FASTA: opt: 567 Z-score: 672.1 E(): 1.5e-29 Smith-Waterman score: 567; 37.984 identity in 258 aa overlap YP_169292.1 Similar to Q9F1M9 MurC from Shewanella violacae (494 aa). FASTA: opt: 1010 Z-score: 1212.3 E(): 1.2e-59 Smith-Waterman score: 1010; 36.761 identity in 457 aa overlap YP_169293.1 Similar to Q87SH3 Conserved hypothetical protein from Vibrio parahaemolyticus (287 aa). FASTA: opt: 744 Z-score: 882.7 E(): 2.8e-41 Smith-Waterman score: 744; 46.996 identity in 283 aa overlap ORF ftt0240 YP_169294.1 ORF ftt0241c YP_169295.1 Similar to Q83DS9 Hypothetical protein CBU0616 from Coxiella burnetii (196 aa). FASTA: opt: 376 Z-score: 484.1 E(): 4.5e-19 Smith-Waterman score: 376; 37.634 identity in 186 aa overlap ORF ftt0242 YP_169296.1 weak similarity to M. musculus protein,1700056O17 Rik protein (233 aa) ORF ftt0243 YP_169297.1 Similar to Q8R5Z3 DNA/RNA helicase (DEAD/DEAH box family) from Fusobacterium nucleatum (942 aa). FASTA: opt: 2318 Z-score: 2654.5 E(): 5.8e-140 Smith-Waterman score: 2473; 45.087 identity in 916 aa overlap ORF ftt0244 YP_169298.1 Similar to Q8PWX4 Universal stress protein from Methanosarcina maizae (323 aa). FASTA: opt: 347 Z-score: 418.2 E(): 2.1e-15 Smith-Waterman score: 347; 31.849 identity in 292 aa overlap YP_169299.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169300.1 ORF ftt0248 YP_169301.1 Similar to Q8ZJH5 Ferrous iron transport protein B from Yersinia pestis (771 aa). FASTA: opt: 1928 Z-score: 2034.7 E(): 1.9e-105 Smith-Waterman score: 2307; 45.396 identity in 771 aa overlap YP_169302.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_169303.1 Similar to Q8Y1X0 Probable branched-chain amino acid aminotransferase protein from Ralstonia solanacearum (309 aa). FASTA: opt: 706 Z-score: 903.1 E(): 2.1e-42 Smith-Waterman score: 706; 39.931 identity in 288 aa overlap YP_169304.1 Similar to Q9C5X5 2-isopropylmalate synthase from Arabidopsis thaliana (503 aa). FASTA: opt: 493 Z-score: 601.2 E(): 1.4e-25 Smith-Waterman score: 635; 31.373 identity in 408 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein YP_169305.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169308.1 Similar to Q87T79 lipopolysaccharide A protein from Vibrio parahaemolyticus (311 aa). FASTA: opt: 835 Z-score: 996.3 E(): 1.3e-47 Smith-Waterman score: 910; 43.671 identity in 316 aa overlap ORF ftt0256c YP_169309.1 Similar to Q8YNW1 Ribonuclease II family protein from Anabaena sp. (686 aa). FASTA: opt: 557 Z-score: 649.1 E(): 2.9e-28 Smith-Waterman score: 763; 28.290 identity in 661 aa overlap ORF ftt0257 YP_169310.1 Similar to Q83AC9 Carboxylesterase/phospholipase family protein from Coxiella burnetii (200 aa). FASTA: opt: 599 Z-score: 736.0 E(): 4.2e-33 Smith-Waterman score: 599; 45.813 identity in 203 aa overlap ORF ftt0258 YP_169311.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_169312.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_169313.1 The predicted signal peptide are in conflict with the membrane lipoprotein lipid attachment site ORF ftt0261 YP_169314.1 The predicted signal peptide and the membrane lipoprotein lipid attachment site are in conflict with each other ORF ftt0262 YP_169316.1 Similar to Q8Y1X1 Hypothetical protein RSc0566 from Ralstonia solancearum (65 aa). FASTA: opt: 160 Z-score: 236.6 E(): 2.5e-05 Smith-Waterman score: 160; 50.000 identity in 36 aa overlap ORF ftt0264c YP_169317.1 Similar to Q83AV7 ABC transporter,permease protein from Coxiella burnetii (581 aa). FASTA: opt: 976 Z-score: 1115.9 E(): 2.9e-54 Smith-Waterman score: 1738; 45.318 identity in 598 aa overlap ORF ftt0265 YP_169318.1 Similar to Q83AV8 ABC transporter, ATP-binding protein from Coxiella burnetii (432 aa). FASTA: opt: 1556 Z-score: 1713.5 E(): 1.5e-87 Smith-Waterman score: 1556; 54.673 identity in 428 aa overlap ORF ftt0266 YP_169319.1 ORF ftt0267 YP_169320.1 Similar to Q88MV1 Sodium/hydrogen exchanger family protein from Pseudomonas putida (601 aa). FASTA: opt: 1318 Z-score: 1419.4 E(): 3.6e-71 Smith-Waterman score: 1318; 37.993 identity in 608 aa overlap ORF ftt0268 YP_169321.1 Similar to Q8EKP8 Carbonic anhydrase,family 3 from Shewanella oneidensis (182 aa). FASTA: opt: 639 Z-score: 840.8 E(): 6.1e-39 Smith-Waterman score: 639; 50.000 identity in 178 aa overlap ORF ftt0269 YP_169322.1 Similar to Q83AQ2 Outer membrane lipoprotein LolB, from Coxiella burnetii (210 aa). FASTA: opt: 395 Z-score: 508.7 E(): 1.9e-20 Smith-Waterman score: 395; 33.668 identity in 199 aa overlap YP_169323.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_169324.1 ORF ftt0272 YP_169325.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169327.1 Similar to Q937K9 YbgT protein from Erwinia chrysanthemi (38 aa). FASTA: opt: 81 Z-score: 153.9 E(): 1 Smith-Waterman score: 81; 42.857 identity in 28 aa overlap ORF ftt0277c YP_169328.1 Similar to AAO69749 (Q8XGM0) Cytochrome d ubiquinol oxidase subunit II from Salmonella typhi (379 aa). FASTA: opt: 645 Z-score: 711.2 E(): 1e-31 Smith-Waterman score: 1022; 40.506identity in 395 aa overlap YP_169329.1 Similar to AAP96534 (Q7VKT6) Cytochrome D ubiquinol oxidase, subunit I from Haemophilus ducreyi (516 aa). FASTA: opt: 1311 Z-score: 1457.7 E(): 2.7e-73 Smith-Waterman score: 1688; 47.478identity in 575 aa overlap Schu S4 seems to have extra sequence in between 340-420 aa YP_169330.1 Similar to AAO89830 (Q83EP3) Major facilitator family transporter from Coxiella burnetii (458 aa). FASTA: opt: 1379 Z-score: 1410.6 E(): 1.1e-70 Smith-Waterman score: 1379; 46.102 identity in 449 aa overlap YP_169331.1 Similar to Q87DQ7 Cytochrome O ubiquinol oxidase subunit II from Xylella fastidiosa (319 aa). FASTA: opt: 956 Z-score: 1145.6 E(): 6.4e-56 Smith-Waterman score: 956; 49.477 identity in 287 aa overlap YP_169332.1 Similar to AAO70008 (Q8XG02) Cytochrome o ubiquinol oxidase subunit I from Salmonella typhi (663 aa). FASTA: opt: 3045 Z-score: 3221.2 E(): 1.6e-171 Smith-Waterman score: 3045; 64.361identity in 665 aa overlap YP_169333.1 Similar to Q87IH7 Cytochrome o ubiquinol oxidase, subunit III from Vibrio parahaemolyticus (200 aa). FASTA: opt: 768 Z-score: 931.9 E(): 5.1e-44 Smith-Waterman score: 768; 55.276identity in 199 aa overlap YP_169334.1 Similar to Q8ZC55 Cytochrome O ubiquinol oxidase subunit IV from Yersinia pestis (110 aa). FASTA: opt: 325 Z-score: 419.7 E(): 1.7e-15 Smith-Waterman score: 325; 50.505 identity in 99 aa overlap YP_169335.1 converts protoheme IX and farnesyl diphosphate to heme O YP_169336.1 Similar to Q8A014 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase from Bacteroides thetaiotaomicron (346 aa). FASTA: opt: 687 Z-score: 795.8 E(): 2e-36 Smith-Waterman score: 687; 33.431 identity in 341 aa overlap paralog of FTT1571 YP_169337.1 Similar to Q8XIW2 Hypothetical protein CPE2001 from Clostridium perfringens (229 aa). FASTA: opt: 806 Z-score: 994.2 E(): 1.7e-47 Smith-Waterman score: 806; 51.948 identity in 231 aa overlap ORF ftt0287c YP_169338.1 Similar to Q8D4Q2 Pyridoxal/pyridoxine/pyridoxamine kinase from Vibrio vulnificus (290 aa). FASTA: opt: 611 Z-score: 766.0 E(): 8.9e-35 Smith-Waterman score: 611; 38.545identity in 275 aa overlap YP_169339.1 ORF ftt0289c YP_169340.1 Similar to Q87YN6 MoxR protein, , from Pseudomonas syringae (319 aa). FASTA: opt: 1309 Z-score: 1518.5 E(): 9.9e-77 Smith-Waterman score: 1309; 61.489 identity in 309 aa overlap YP_169341.1 Similar to Q87YN5 Conserved hypothetical protein from Pseudomonas syringae (314 aa). FASTA: opt: 561 Z-score: 693.3 bits: 136.4 E(): 1e-30 Smith-Waterman score: 561; 30.479 identity in 292 aa overlap ORF ftt0291 YP_169342.1 Similar to Q8D3W9 Conserved hypothetical protein from Vibrio vulnificus (156 aa). FASTA: opt: 228 Z-score: 276.8 E(): 1.5e-07 Smith-Waterman score: 228; 28.481 identity in 158 aa overlap ORF ftt0292 YP_169343.1 Similar to Q88LA6 Von Willebrand factor type A domain protein from Pseuodmonas putida (358 aa). FASTA: opt: 905 Z-score: 1015.4 E(): 1.1e-48 Smith-Waterman score: 905; 45.122 identity in 328 aa overlap ORF ftt0293 YP_169344.1 Similar to Q8ECP0 Conserved hypothetical protein from Shewanella oneidensis (555 aa). FASTA: opt: 529 Z-score: 628.4 E(): 4.1e-27 Smith-Waterman score: 529; 24.371 identity in 517 aa overlap ORF ftt0295 YP_169345.1 Similar to PCP_CLOPE (Q8XKH1) Pyrrolidone-carboxylate peptidase from Clostridium perfringens (215 aa). FASTA: opt: 710 Z-score: 844.3 E(): 3.9e-39 Smith-Waterman score: 710; 52.020identity in 198 aa overlap YP_169346.1 ORF ftt0297 YP_169347.1 Similar to Q8XWQ9 Probable DNA polymerase III (CHI subunit) protein from Ralstonia solanacearum (142 aa). FASTA: opt: 142 Z-score: 187.9 E(): 0.013 Smith-Waterman score: 142; 30.000identity in 120 aa overlap YP_169348.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_169349.1 ORF ftt0300 YP_169350.1 ORF ftt0301 YP_169351.1 ORF ftt0302 YP_169352.1 Similar to Q9JTX1 L-lactate dehydrogenase from Neisseria meningitidis (390 aa). FASTA: opt: 1591 Z-score: 1977.5 E(): 3e-102 Smith-Waterman score: 1591; 60.789 identity in 380 aa overlap YP_169353.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_169354.1 Similar to Q88NZ1 MutT/nudix family protein from Pseuodomonas putida (137 aa). FASTA: opt: 224 Z-score: 293.2 E(): 1.8e-08 Smith-Waterman score: 224; 34.545 identity in 110 aa overlap ORF ftt0305 YP_169355.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_169356.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_169357.1 ORF ftt0308 YP_169358.1 ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 transposase from Francisella tularensis (247 aa). YP_169359.1 Similar to Q8XT33 Probable amino-acid permease transmembrane protein from Ralstonia solanacearum (543 aa). FASTA: opt: 999 Z-score: 1146.0 E(): 5.5e-5 Smith-Waterman score: 999; 34.924 identity in 461 aa overlap ORF ftt0310 YP_169360.1 Similar to Q9KKV6 Hypothetical protein VCA0994 from Vibrio cholerae (326 aa). FASTA: opt: 558 Z-score: 686.8 E(): 2.3e-30 Smith-Waterman score: 558; 31.949 identity in 313 aa overlap ORF ftt0311c YP_169361.1 Similar to Q9K7B6 Dihydrofolate reductase from Bacillus halodurans (163 aa). FASTA: opt: 465 Z-score: 598.3 E(): 2e-25 Smith-Waterman score: 465; 41.566 identity in 166 aa overlap YP_169362.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_169363.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_169364.1 Catalyzes the phosphorylation of UMP to UDP YP_169365.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_169366.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_169367.1 Similar to Q88MH5 Phosphatidate cytidylyltransferase from Pseudomonas putida (271 aa). FASTA: 398 opt: 534 Z-score: 626.6 E(): 5.2e-27 Smith-Waterman score: 536; 35.926 identity in 270 aa overlap YP_169368.1 catalyzes the formation of dUMP from dUTP YP_169369.1 Similar to Q8XFD0 Phosphotidylglycerophosphate synthetase from Salmonella typhi (182 aa). FASTA: opt: 575 Z-score: 728.4 E(): 1.1e-32 Smith-Waterman score: 618; 50.000identity in 188 aa overlap YP_169370.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_169371.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_169372.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_169373.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_169374.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_169375.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_169376.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_169377.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_169378.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_169379.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_169380.3 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_169381.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_169382.1 one of the stabilizing components for the large ribosomal subunit YP_169383.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_169384.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_169385.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_169386.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_169387.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_169388.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_169389.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_169390.1 binds 5S rRNA along with protein L5 and L25 YP_169391.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_169392.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_169393.1 late assembly protein YP_169394.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_169395.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_169396.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_169397.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_169398.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_169399.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_169400.1 is a component of the macrolide binding site in the peptidyl transferase center YP_169401.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169402.1 Duplicate of FTT0378 and FTT1263 ORF ftt0354 YP_169403.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169404.1 molecular chaperone YP_169405.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169406.1 ORF ftt0359 YP_169407.1 Similar to Q82V84 Short-chain dehydrogenase/reductase (SDR) superfamily from Nitrosomonas europaea (279 aa). FASTA: opt: 829 Z-score: 982.8 E(): 7.5e-47 Smith-Waterman score: 829; 49.632 identity in 272 aa overlap ORF ftt0360 YP_169408.1 Similar to Q8Z506 amino acid transporter from Salmonella typhi (473 aa). FASTA: opt: 717 Z-score: 754.8 E(): 3.8e-34 Smith-Waterman score: 755; 29.783 identity in 460 aa overlap ORF ftt0361c YP_169409.1 ORF ftt0362c YP_169410.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169411.1 ORF ftt0364c YP_169412.1 Similar to Q8PFB8 Phenol hydroxylase from Xanthomonas axonopodis (365 aa). FASTA: opt: 567 Z-score: 717.5 E(): 4.5e-32 Smith-Waterman score: 567; 38.211 identity in 246 aa overlap The protein seems to be shorter (<115 aa) than the matching proteins. YP_169413.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_169414.1 Similar to Q88AR1 Glutamate--cysteine ligase from Pseudomonas syringae (529 aa). FASTA: opt: 1113 Z-score: 1281.1 E(): 1.8e-63 Smith-Waterman score: 1113; 39.250 identity in 507 aa overlap YP_169415.1 Similar to AAO89943 (Q83ED5) Integral membrane protein MviN from Coxiella burnetii (515 aa). FASTA: opt: 836 Z-score: 887.1 E(): 1.6e-41 Smith-Waterman score: 836; 30.452 identity in 509 aa overlap YP_169416.1 ORF ftt0369c YP_169417.1 Similar to Q8Z189 Hypothetical protein yjeE from Salmonella typhi (153 aa). FASTA: opt: 517 Z-score: 623.3 E(): 7.9e-27 Smith-Waterman score: 517; 56.489 identity in 131 aa overlap YP_169418.1 Similar to Q8ECR5 FolC bifunctional protein from Shewanella oneidensis (431 aa). FASTA: opt: 507 Z-score: 630.2 E(): 3.3e-27 Smith-Waterman score: 627; 32.274 identity in 409 aa overlap YP_169419.1 Similar to Q8XFJ5 Acetyl-CoA carboxylase beta subunit from Salmonella typhi (304 aa). FASTA: opt: 1197 Z-score: 1430.2 E(): 9.1e-72 Smith-Waterman score: 1197; 62.116 identity in 293 aa overlap YP_169420.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_169421.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_169422.1 Weak hits at position aa 250-350 to many cytochrome oxidase subunit I eg:(Q85L50). ORF ftt0376c YP_169423.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169424.1 Duplicate of FTT0354 and FTT1263 ORF ftt0378c YP_169425.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_169426.1 ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 transposase from Francisella tularensis (247 aa). YP_169427.1 ORF ftt0382 YP_169428.1 ORF ftt0383 YP_169429.2 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_169430.1 ORF ftt0385 YP_169431.1 NadM-Nudix subfamily; involved in creation of nicotanimide adenine dinucleotide NAD from either biosynthetic or salvage pathways YP_169432.1 Similar to Q9KNH7 UDP-N-acetylglucosamine pyrophosphorylase from Vibrio cholerae (453 aa). FASTA: opt: 1597 Z-score: 1863.6 E(): 6.5e-96 Smith-Waterman score: 1597; 53.201 identity in 453 aa overlap YP_169433.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_169434.1 Similar to Q9RWR2 Acetyltransferase, , from Deinococcus radiodurans (188 aa). FASTA: opt: 188 Z-score: 245.7 E(): 8.5e-06 Smith-Waterman score: 188; 28.105 identity in 153 aa overlap ORF ftt0389 YP_169435.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_169436.1 Similar to Q8D6M5 Cold shock protein from Vibrio vulnificus (70 aa). FASTA: opt: 272 Z-score: 403.6 E(): 1.4e-14 Smith-Waterman score: 272; 58.571 identity in 70 aa overlap YP_169437.1 Similar to Q8TT97 Hypothetical protein MA0540 from Methanosarcina mazei (95 aa). FASTA: opt: 151 Z-score: 197.5 E(): 0.0038 Smith-Waterman score: 151; 35.789 identity in 95 aa overlap ORF ftt0392c YP_169438.1 Similar to Q886P4 Methionine aminopeptidase,type I from Pseudomonas syringae (260 aa). FASTA: opt: 1243 Z-score: 1568.2 E(): 1.9e-79 Smith-Waterman score: 1243; 70.120 identity in 251 aa overlap YP_169439.1 ORF ftt0394 YP_169440.1 Similar to Q9L5J1 hypothetical protein from Salmonella typhi (259 aa). FASTA: opt: 585 Z-score: 707.5 E(): 1.6e-31 Smith-Waterman score: 680; 46.743 identity in 261 aa overlap ORF ftt0395 YP_169441.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_169442.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_169443.1 ORF ftt0398c YP_169444.1 Similar to Q885D8 BNR/Asp-box repeat protein from Pseudomonas syringae (432 aa). FASTA: opt: 536 Z-score: 654.4 E(): 1.5e-28 Smith-Waterman score: 536; 31.922 identity in 307 aa overlap ORF ftt0399c YP_169445.1 Similar to Q88L07 Soluble lytic transglycosylase, from Pseudomonas putida (657 aa). FASTA: opt: 596 Z-score: 646.0 E(): 3.9e-28 Smith-Waterman score: 819; 27.822 identity in 629 aa overlap. YP_169446.1 Partial homology to carboxy terminus of Q9CLV4a Hypothetical protein PM1097 from Pasteurella multocida (417 aa). FASTA: opt: 269 Z-score: 330.3 E(): 1.7e-10 Smith-Waterman score: 269; 26.050identity in 238 aa overlap ORF ftt0401 YP_169447.1 Similar to DP3A_SALTY (P14567) DNA polymerase III alpha subunit from Salmonella typhimurium (1160 aa). FASTA: opt: 3099 Z-score: 3288.3 E(): 2.6e-175 Smith-Waterman score: 3099; 44.781identity in 1121 aa overlap. YP_169448.1 Similar to DEF_LEPIN (Q93LE9) Peptide deformylase from Leptospira interrogans (178 aa). FASTA: opt: 312 Z-score: 399.2 E(): 2.4e-14 Smith-Waterman score: 312; 35.758 identity in 165 aa overlap YP_169449.1 Similar to Q83CV1 lipoprotein ABC transporter,permease protein from Coxiella burnetii (414 aa). FASTA: opt: 1273 Z-score: 1436.4 E(): 4.1e-72 Smith-Waterman score: 1273; 48.104 identity in 422 aa overlap YP_169450.1 Similar to LOLD_NEIMA (P57030) Lipoprotein releasing system ATP-binding transport protein from Neisseria meningitidis (231 aa). FASTA: opt: 791 Z-score: 892.8 E(): 7e-42 Smith-Waterman score: 791; 51.770 identity in 226 aa overlap YP_169451.1 Similar to DCLY_ECOLI (P23892) Lysine decarboxylase, inducible from E. coli (715 aa) FASTA: opt: 2608 Z-score: 3095.0 E(): 1.7e-164 Smith-Waterman score: 2608; 53.912 identity in 703 aa overlap YP_169452.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_169453.1 Similar to Q8FE66 Glycine cleavage system H protein from E coli (130 aa). FASTA: opt: 526 Z-score: 699.9 E(): 4.3e-31 Smith-Waterman score: 526; 60.938 identity in 128 aa overlap YP_169454.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein YP_169455.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein YP_169456.1 Similar to Q8FQC7 shikimate 5-dehydrogenase from Corynebacterium efficiens(269 aa). FASTA: opt: 283 Z-score: 321.7 E(): 4.6e-10 Smith-Waterman score: 287; 28.077 identity in 260 aa overlap. YP_169457.1 Similar to Q8XK16 Pullulanase from Clostridium perfringens (1064 aa). FASTA: opt: 3419 Z-score: 3958.4 E(): 1.4e-212 Smith-Waterman score: 3419; 48.369identity in 1042 aa overlap Other FASTA hits have lower scores due to generally being smaller in size. Q8XK16 is an electronic annotation YP_169458.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_169459.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_169460.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_169461.1 Similar to Q8DN49 Maltodextrin phosphorylase from Streptococcus pneumoniae (752 aa). FASTA: opt: 2938 Z-score: 3443.0 E(): 6.9e-184 Smith-Waterman score: 2938; 59.569 identity in 742 aa overlap YP_169462.1 amylomaltase; acts to release glucose from maltodextrins YP_169463.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_169464.1 Similar to MURE_NEIMB (Q9K0Y9) UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase from Neisseria meningitidis (492 aa). FASTA: opt: 1037 Z-score: 1223.7, E(): 2.9e-60 Smith-Waterman score: 1037; 40.795 identity in 478 aa overlap YP_169465.1 Similar to Q87SG8 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate -D-alanyl-D-alanyl ligase from Vibrio parahaemolyticus (454 aa). FASTA: opt: 870 Z-score: 1005.8 E(): 3.9e-48 Smith-Waterman score: 870; 35.011 identity in 457 aa overlap YP_169466.1 ORF ftt0423 YP_169468.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_169469.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_169470.1 Similar to SPEH_METJA (Q57763) S-adenosylmethionine decarboxylase proenzyme from Methanococcus jannaschii (124 aa). FASTA: opt: 355 Z-score: 487.2, E(): 3e-19 Smith-Waterman score: 355; 44.737 identity in 114 aa overlap YP_169471.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_169472.1 Similar to Q8A2B1 arginine decarboxylase from Bacteroides thetaiotamicron (630 aa). FASTA: opt: 571 Z-score: 678.2 E(): 6.9e-30 Smith-Waterman score: 689; 28.755 identity in 546 aa overlap YP_169473.1 ORF ftt0433 YP_169474.1 Similar to Q8KCB6 Hypothetical protein CT1508 from Chlorobium tepidum (347 aa). FASTA: opt: 742 Z-score: 939.4 E(): 2e-44 Smith-Waterman score: 837; 38.484 identity in 343 aa overlap PAD_porph is a possible virulence factor for P. gingivalis: PMID: 10377098 ORF ftt0434 YP_169475.1 Similar to Q87NU4 carbon-nitrogen hydrolase from Vibrio parahaemolyticus (288 aa). FASTA: opt: 1139 Z-score: 1419.0 E(): 3.8e-71 Smith-Waterman score: 1139; 57.971 identity in 276 aa overlap. Possible candidate for citrulline ureidase ORF ftt0435 YP_169476.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_169477.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_169478.1 Similar to MPL_ECOLI (P37773) UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diamino pimelate ligase (murein peptide ligase) from E coli (457 aa). FASTA: opt: 1392, Z-score: 1656.5, E(): 2.3e-84,Smith-Waterman score: 1392; 47.912 identity in 455 aa overlap YP_169479.1 Similar to YJFH_ECOLI (P39290) hypothetical tRNA/rRNA methyltransferase yjfH from E. coli (243 aa). FASTA: opt: 556, Z-score: 695.5, E(): 7.5e-31 Smith-Waterman score: 556; 43.128 identity in 211 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element close to the C-terminal. It is not clear whether this insertion affects the function of the protein YP_169480.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169481.1 Similar to Q8EU72 Bicyclomycin resistance protein from Oceanobacillus iheyensis (412 aa). FASTA: opt: 614 Z-score: 668.2 E(): 2.5e-29 Smith-Waterman score: 614; 30.179identity in 391 aa overlap ORF ftt0442c YP_169482.1 Similar to Q83C03 Conserved domain protein from Coxiella burnetii (377 aa). FASTA: opt: 359 Z-score: 409.9 E(): 6.1e-15 Smith-Waterman score: 380; 27.350 identity in 351 aa overlap ORF ftt0443 YP_169483.1 Similar to Q83CB9 Multidrug transporter, from Coxiella burnetii (412 aa). FASTA: opt: 558 Z-score: 638.9 E(): 1.1e-27 Smith-Waterman score: 558; 25.854identity in 410 aa overlap. Similar to tetA and tetC which are situated on a plasmid in E. coli YP_169484.1 Similar to Q83RB7 transport protein from Shigella flexneri (500 aa). FASTA: opt: 567 Z-score: 573.2 E(): 4.9e-24 Smith-Waterman score: 578; 26.122 identity in 490 aa overlap ORF ftt0446 YP_169485.1 Similar to Q83DW3 Hypothetical protein from Coxiella burnetii (497 aa). FASTA: opt: 334 Z-score: 356.6 E(): 5.7e-12 Smith-Waterman score: 336; 24.129 identity in 402 aa overlap ORF ftt0447c YP_169486.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_169487.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_169488.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_169489.1 Similar to MURD_CHLCV (Q821S1) UDP-N-acetylmuramoylalanine--D-glutamate ligase from Chlamydophila caviae (419 aa) FASTA: opt: 516 Z-score: 615.2 E(): 2.2e-26 Smith-Waterman score: 549; 28.000 identity in 425 aa overlap YP_169490.1 Similar to Q9KPG6 Cell division protein FtsW from Vibrio cholerae (398 aa). FASTA: opt: 1114 Z-score: 1237.3 E(): 5e-61 Smith-Waterman score: 1114; 44.892 identity in 372 aa overlap YP_169491.1 Similar to Q83DW2 Hypothetical protein from Coxiella burnetii (273 aa). FASTA: opt: 554 Z-score: 648.8 E(): 3e-28 Smith-Waterman score: 554; 37.407identity in 270 aa overlap ORF ftt0453c YP_169492.1 Similar to Q83DW4 Glycosyl transferase, group 2 family protein from Coxiella burnetii (324 aa). FASTA: opt: 896 Z-score: 1055.7 E(): 6.5e-51 Smith-Waterman score: 896; 43.189identity in 301 aa overlap YP_169493.1 Similar to Q8XQM9 Probable transmembrane protein from Ralstonia solanacearum (551 aa). FASTA: opt: 683 Z-score: 749.4 E(): 7.6e-34 Smith-Waterman score: 683; 29.174 identity in 545 aa overlap ORF ftt0455c YP_169494.1 Similar to Y941_COXBU Hypothetical UPF0269 protein CBU0941 from Coxiella burnetii (90 aa). FASTA: opt: 346 Z-score: 470.4 E(): 2.6e-18 Smith-Waterman score: 346; 55.422 identity in 83 aa overlap ORF ftt0456c YP_169495.1 Similar to Q9CNM6 Hypothetical protein PM0401 from Pasteurella multocida (109 aa). initn: 382 init1: 382 opt: 382 Z-score: 511.4 bits: 99.7 E(): 1.4e-20 Smith-Waterman score: 382; 58.586identity (58.58639ngapped) in 99 aa overlap YP_169496.1 Similar to SSPA_HAESO (P31784) Stringent starvation protein A homolog from Haemophilus somnus (212 aa). FASTA: opt: 377 Z-score: 473.8 E(): 1.7e-18 Smith-Waterman score: 377; 35.106 identity in 188 aa overlap YP_169497.1 SohB; periplasmic protein; member of the peptidase S49 family YP_169498.1 Similar to Q8D3A6 HolB protein from Wigglesworthia glossinidia brevipalpis (329 aa). FASTA: opt: 315 Z-score: 378.8 E(): 3.3e-13 Smith-Waterman score: 315; 27.304 identity in 293 aa overlap YP_169499.1 Similar to Q87LZ3 RNA-binding protein containing KH domain from Vibrio parahaemolyticus (98 aa). FASTA: opt: 289 Z-score: 405.9 E(): 1e-14 Smith-Waterman score: 289; 52.222 identity in 90 aa overlap YP_169500.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_169501.1 Similar to Q8E8X2 RNA methyltransferase, TrmH family, group 2 from Shewanella oneidensis (154 aa). FASTA: opt: 569 Z-score: 759.8 E(): 2e-34 Smith-Waterman score: 569; 57.616 identity in 151 aa overlap YP_169502.1 Similar to ASG2_HAEIN (P43843) Probable L-asparaginase periplasmic [Precursor] from Haemophilus influenzae (349 aa). FASTA: opt: 897 Z-score: 1034.7 E(): 9.6e-50 Smith-Waterman score: 897; 43.966 identity in 348 aa overlap. No signal peptide predicted YP_169504.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_169505.1 Similar to OSTA_XYLFT (Q87AI9) Organic solvent tolerance protein from Xylella fastidiosa (792 aa). FASTA: opt: 700 Z-score: 808.7 E(): 3.7e-37 Smith-Waterman score: 775; 26.572 identity in 636 aa overlap YP_169506.1 Similar to Q8ZIK4 Survival protein SurA (Peptidyl-prolyl cis-trans isomerase) from Yersinia pestis (434 aa). FASTA: opt: 532 Z-score: 586.9 E(): 8.4e-25 Smith-Waterman score: 532; 25.176 identity in 425 aa overlap YP_169507.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_169508.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_169509.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_169510.1 Similar to BCCP_PSEAE (P37799) Biotin carboxyl carrier protein of acetyl-CoA carboxylase from Pseudomonas aeruginosa (156 aa). FASTA: opt: 466 Z-score: 537.8 E(): 4.6e-22 Smith-Waterman score: 466; 48.148 identity in 162 aa overlap YP_169511.1 Similar to Q9KV62 Acetyl-CoA carboxylase, biotin carboxylase subunit from Vibrio cholerae (447 aa). FASTA: opt: 2119 Z-score: 2505.5 E(): 1.2e-131 Smith-Waterman score: 2119; 70.270 identity in 444 aa overlap YP_169512.1 ORF ftt0474 YP_169513.1 Similar to Q87G16 (Q87G16) membrane protein from Vibrio parahaemolyticus (365 aa). FASTA: opt: 362 Z-score: 432.0 E(): 3.6e-16 Smith-Waterman score: 412; 29.167 identity in 384 aa overlap YP_169514.1 Similar to Q83AR3 (Q83AR3) Lysyl-tRNA synthetase-related protein from Coxiella burnetii (321 aa). FASTA: opt: 727 Z-score: 890.9 E(): 9.9e-42 Smith-Waterman score: 727; 42.088 identity in 297 aa overlap YP_169515.1 Similar to Q83CV0 BirA bifunctional protein from Coxiella burnetii (323 aa). FASTA: opt: 375 Z-score: 457.7 E(): 1.3e-17 Smith-Waterman score: 375; 31.004 identity in 229 aa overlap YP_169516.1 Similar to RECJ_HAEIN (P45112) single-stranded-DNA-specific exonuclease from Haemophilus influenzae (575 aa). FASTA: opt: 869 Z-score: 996.6 E(): 1.3e-47 Smith-Waterman score: 902; 32.028identity in 562 aa overlap YP_169517.1 Similar to Q9I4W6 Hypothetical protein PA1007 from Pseudomonas aeruginosa (357 aa). FASTA: opt: 1016 Z-score: 1092.5 E(): 5.8e-53 Smith-Waterman score: 1016; 40.698 identity in 344 aa overlap YP_169518.1 Similar to Q8YBJ1 Glutamate:gamma-aminobutyrate antiporter from Brucella melitensis (510 aa). FASTA: opt: 983 Z-score: 1079.5 E(): 3.1e-52 Smith-Waterman score: 983; 34.698 identity in 464 aa overlap YP_169519.1 Similar to Q92RX4 Probable putrescine-binding periplasmic protein from Rhizobium meliloti (364 aa). FASTA: opt: 847 Z-score: 993.2 E(): 2e-47 Smith-Waterman score: 847; 35.714 identity in 350 aa overlap YP_169520.1 ORF ftt0482c YP_169521.1 Similar to AAP95905 (AAP95905) Hypothetical protein from Haemophilus ducreyi 35000HP (342 aa). FASTA: opt: 686 Z-score: 815.5 E(): 1.6e-37 Smith-Waterman score: 686; 40.678 identity in 295 aa overlap ORF ftt0483c YP_169522.1 ORF ftt0484 YP_169523.1 ORF ftt0485 YP_169524.1 Similar to MUTL_RICPR (Q9ZC88) DNA mismatch repair protein mutL from Rickettsia prowazekii (595 aa). FASTA: opt: 1236 Z-score: 1435.6 E(): 4.5e-72 Smith-Waterman score: 1236; 37.291 identity in 598 aa overlap YP_169526.1 Similar to Q83BM0 Major facilitator family transporter from Coxiella burnetii (428 aa). FASTA: opt: 319 Z-score: E(): 3.7e-11 Smith-Waterman score: 319; 21.951 identity in 369 aa overlap ORF ftt0488c YP_169527.1 Similar to Q8ZGC9 Thioredoxin reductase from Yersinia pestis (320 aa). FASTA: opt: 1525 Z-score: 1798.2 E(): 2.9e-92 Smith-Waterman score: 1525; 70.927 identity in 313 aa overlap YP_169528.1 Similar Q888K0 Phospholipase D family protein from Pseudomonas syringae (pv. tomato) (422 aa). FASTA: opt: 440 Z-score: 514.4 E(): 9.2e-21 Smith-Waterman score: 440; 25.840 identity in 387 aa overlap ORF ftt0490c YP_169529.1 Similar to Q82SZ4 Phosphoglycolate phosphatase from Nitrosomonas europaea (240 aa). FASTA: opt: 432 Z-score: 532.2 E(): 9.4e-22 Smith-Waterman score: 432; 33.486 identity in 218 aa overlap YP_169530.1 Similar to Q87J66 Transcriptional regulator, LysR family from Vibrio parahaemolyticus (311 aa). FASTA: opt: 675 Z-score: 768.6 E(): 6.4e-35 Smith-Waterman score: 675; 33.115 identity in 305 aa overlap YP_169531.1 Similar Q9CNA6 Hypothetical protein PM0526 from Pasteurella multocida (244 aa). FASTA: opt: 521 Z-score: 651.2 E(): 2.2e-28 Smith-Waterman score: 521; 40.175 identity in 229 aa overlap YP_169532.1 Similar to Q9K0Q8 Hypothetical protein NMB0526 from Neisseria meningitidis (serogroup B) (172 aa). FASTA: opt: 455 Z-score: 573.9 E(): 4.5e-24 Smith-Waterman score: 455; 42.353 identity in 170 aa overlap ORF ftt0495 YP_169533.1 Similar to Q935B8 Hypothetical protein HCM2.0044c from Salmonella typhi (251 aa). FASTA: opt: 242 Z-score: 297.7 E(): 1.1e-08 Smith-Waterman score: 296; 28.000 identity in 250 aa overlap ORF ftt0496 YP_169536.1 Similar to Q9I0I7 Hypothetical protein PA2651 from Pseudomonas aeruginosa (352 aa). FASTA: opt: 382 Z-score: 397.1 E(): 3.2e-14 Smith-Waterman score: 382; 26.686 identity in 341 aa overlap ORF ftt0501c YP_169537.1 ORF ftt0502c YP_169538.1 Similar to Q9JUS9 succinyl-CoA synthetase alpha from Neisseria meningitidis (serogroup A) (296 aa). FASTA: opt: 1574 Z-score: 1817.5 E(): 2.4e-93 Smith-Waterman score: 1574; 81.661identity in 289 aa overlap YP_169539.1 catalyzes the interconversion of succinyl-CoA and succinate YP_169540.1 ORF ftt0505 YP_169541.1 ORF ftt0506c YP_169542.1 Similar to Q9X610 BcfH from Salmonella typhimurium (269 aa). FASTA: opt: 305 Z-score: 371.4 E(): 8.5e-13 Smith-Waterman score: 305; 31.122 identity in 196 aa overlap ORF ftt0507 YP_169543.1 Similar to Y926_SYNY3 (P72872) Hypothetical protein sll0926 from Synechocystis sp. (strain PCC 6803) (334 aa). FASTA: opt: 1129 Z-score: 1337.0 E(): 1.4e-66 Smith-Waterman score: 1129; 51.911 identity in 314 aa overlap YP_169544.1 Similar to Q8DBN3 Conserved hypothetical protein from Vibrio vulnificus (184 aa). FASTA: opt: 275 Z-score: 356.8 E(): 5.5e-12 Smith-Waterman score: 275; 30.208 identity in 192 aa overlap ORF ftt0509c YP_169545.1 Similar to GYRB_SALTY (Q60008) DNA gyrase subunit B from Salmonella typhimurium (803 aa). FASTA: opt: 3370 Z-score: 3873.3 E(): 7.5e-208 Smith-Waterman score: 3370; 63.321 identity in 807 aa overlap YP_169546.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_169547.3 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_169548.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169549.1 ORF ftt0515 YP_169550.1 Similar to Q9CLW2 PrmA (Ribosomal protein L11 methyltransferase) from Pasteurella multocida (293 aa). FASTA: opt: 572 Z-score: 685.5 E(): 2.7e-30 Smith-Waterman score: 580; 33.677 identity in 291 aa overlap YP_169551.1 Similar to Q9KGG5 Transcriptional regulator involved in nitrogen regulation, NifR3/Smm1 family from Bacillus halodurans (334 aa). FASTA: opt: 1134 Z-score: 1336.1 E(): 1.6e-66 Smith-Waterman score: 1134; 52.484 identity in 322 aa overlap ORF ftt0519 YP_169554.1 Similar to Q89Z57 Type I restriction enzyme EcoAI specificity protein from Bacteroides thetaiotamicron (474 aa). FASTA: opt: 208 Z-score: 239.0 E(): 2e-05 Smith-Waterman score: 246; 24.363 identity in 353 aa overlap ORF ftt0523 YP_169555.1 Similar to Q8KBB0 Hypothetical protein CT1879 from Chlorobium tepidum (193 aa). FASTA: opt: 467 Z-score: 629.2 E(): 3.7e-27 Smith-Waterman score: 467; 60.656 identity in 122 aa overlap ORF ftt0524 YP_169556.1 Similar to RA50_THEVO DNA double-strand break repair rad50 ATPase from Thermoplasma volcanicum (895 aa). FASTA: opt: 188 Z-score: 215.6 E(): 0.0004 Smith-Waterman score: 188; 25.926 identity in 216 aa overlap. Similarity to N terminal domain ORF ftt0525 YP_169557.1 ORF ftt0526 YP_169560.1 Similar to Q97FB4 Intracellular protease/amidase related enzyme from Clostridium acetobutylicum (201 aa). FASTA: opt: 703 Z-score: 884.5 E(): 2.2e-41 Smith-Waterman score: 703; 51.531 identity in 196 aa overlap ORF ftt0530c YP_169561.1 Similar to (glutaredoxin 3) Q8ZJM8 Glutaredoxin 3 from Yersinia pestis (82 aa). FASTA: opt: 181 Z-score: 263.7 E(): 8.5e-07 Smith-Waterman score: 181; 40.260 identity in 77 aa overlap,(ribonucleoside-diphosphate reductase) Q8QYZ8 Ribonucleoside-diphosphate reductase, beta subunit-like protein from Rana tigrina ranavirus (387 aa). FASTA: opt: 1124 Z-score: 1382.6 E(): 4.1e-69 Smith-Waterman score: 1124; 51.703 identity in 323 aa overlap YP_169562.1 Similar to GLR1_ECOLI (P00277) Glutaredoxin 1 from Escherichia coli (85 aa). FASTA: opt: 191 Z-score: 274.9 E(): 2e-07 Smith-Waterman score: 191; 40.000identity in 80 aa overlap YP_169563.1 Catalyzes the rate-limiting step in dNTP synthesis YP_169564.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_169565.1 ORF ftt0536 YP_169566.1 Similar to Q8PD67 Ubiquinone biosynthesis protein from Xanthomonas campestris (217 aa). FASTA: opt: 710 Z-score: 878.4 E(): 4.9e-41 Smith-Waterman score: 710; 51.887 identity in 212 aa overlap (2-211:8-217) ORF ftt0537 YP_169567.1 Similar to Q87LS3 Hypothetical protein from Vibrio parahaemolyticus (203 aa). FASTA: opt: 267 Z-score: 350.1 E(): 1.3e-11 Smith-Waterman score: 320; 31.795 identity in 195 aa overlap ORF ftt0538c YP_169568.1 ORF ftt0540c YP_169569.1 Similar to YQAB_ECOLI (P77475) Hypothetical protein yqaB from Escherichia coli (188 aa). FASTA: opt: 336 Z-score: 422.2 E(): 1.3e-15 Smith-Waterman score: 336; 33.889 identity in 180 aa overlap YP_169570.1 ORF ftt0543 YP_169571.1 Similar to PHNA_ECOLI PhnA protein from Escherichia coli (111 aa). FASTA: opt: 521 Z-score: 674.6 E(): 1.1e-29 Smith-Waterman score: 521; 66.972identity in 109 aa overlap YP_169572.1 ORF ftt0545 YP_169573.1 ORF ftt0546 YP_169575.1 Similar to Q83EK2 DNA polymerase III, epsilon subunit from Coxiella burnetii (232 aa). FASTA: opt: 699 Z-score: 870.8 E(): 1.3e-40 Smith-Waterman score: 699; 49.550 identity in 222 aa overlap YP_169576.1 Similar to Q87AM4 Peptidase (202 aa). FASTA: opt: 481 Z-score: 603.7 E(): 9.8e-26 Smith-Waterman score: 481; 50.000 identity in 142 aa overlap YP_169577.1 Similar to Q8EHZ3 TPR domain protein from Shewanella oneidensis (466 aa). FASTA: opt: 304 Z-score: 346.2 E(): 2.2e-11 Smith-Waterman score: 331; 23.333 identity) in 480 aa overlap ORF ftt0550 YP_169578.1 Similar to Q8P9Q7 Aldehyde dehydrogenase from Xanthomonas campestris (510 aa). FASTA: opt: 1972 Z-score: 2329.9 E(): 6.9e-122 Smith-Waterman score: 1972; 60.285 identity in 491 aa overlap ORF ftt0552 YP_169579.1 Similar to Q8EJ53 Conserved hypothetical protein from Shewanella oneidensis (267 aa). FASTA: opt: 859 Z-score: 1057.9 E(): 4.9e-51 Smith-Waterman score: 859; 52.809 identity in 267 aa overlap ORF ftt0553 YP_169580.1 Similar to Q99SH0 Hypothetical protein SAV2087 from Stafylococcus aureus (97 aa). FASTA: opt: 243 Z-score: 331.6 E(): 1.4e-10 Smith-Waterman score: 243; 45.455 identity in 77 aa overlap ORF ftt0554 YP_169581.1 Similar to Q930P5 Hypothetical protein RA0150 from Rhizobium meliloti (262 aa). FASTA: opt: 924 Z-score: 1048.2 E(): 1.7e-50 Smith-Waterman score: 924; 54.202 identity in 238 aa overlap. Some similarity to glutaredoxin ORF ftt0555 YP_169582.1 Similar to O06466 Oxidative stress transcriptional regulator from Xanthomonas campestris (313 aa). FASTA: opt: 707 Z-score: 842.2 E(): 5.1e-39 Smith-Waterman score: 707; 36.207 identity in 290 aa overlap YP_169583.1 Similar to Q92MY1 Hypothetical protein R02467 from Rhizobium meliloti (180 aa). FASTA: opt: 821 Z-score: 1055.0 E(): 7.2e-51 Smith-Waterman score: 821; 66.092 identity in 174 aa overlap ORF ftt0557 YP_169584.1 Similar to Q8XU62 Hypothetical protein RSc3331 from Ralstonia solanacearum (201 aa). FASTA: opt: 602 Z-score: 724.0 E(): 2e-32 Smith-Waterman score: 602; 48.020 identity in 202 aa overlap ORF ftt0558 YP_169585.1 Similar to KCY_PASMU (P57875) Cytidylate kinase from Pasteurella multocida (227 aa). FASTA: opt: 748 Z-score: 879.9 E(): 4.1e-41 Smith-Waterman score: 748; 53.425 identity in 219 aa overlap YP_169586.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_169587.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169588.1 Similar to Q8EHF2 Polyamine ABC transporter, ATP-binding protein from Shewanella oneidensis (378 aa). FASTA: opt: 1366 Z-score: 1557.5 E(): 7.3e-79 Smith-Waterman score: 1366; 55.496 identity in 373 aa overlap YP_169589.1 Similar to Q8FJE8 Putrescine transport system permease protein from Escherichia coli (314 aa). FASTA: opt: 949 Z-score: 1040.4 E(): 4.7e-50 Smith-Waterman score: 949; 43.878 identity in 294 aa overlap YP_169590.1 Similar to Q8EHF0 Polyamine ABC transporter, permease protein from Shewanella oneidensis (271 aa). FASTA: opt: 873 Z-score: 1010.7 E(): 2.1e-48 Smith-Waterman score: 873; 46.241 identity in 266 aa overlap YP_169591.1 ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 transposase from Francisella tularensis (247 aa). YP_169592.1 ORF ftt0566 YP_169593.1 Similar to Q26545 Phosphoserine phosphohydrolase-like protein trans-spliced from Schistosoma mansoni (223 aa). FASTA: opt: 319 Z-score: 380.8 E(): 2.5e-13 Smith-Waterman score: 319; 29.493 identity in 217 aa overlap. Similar to eukaryotic proteins. Historical HGT-event? ORF ftt0568 YP_169594.1 Similar to Q8P3T2 Integral membrane protein from Xanthomonas campestris (347 aa). FASTA: opt: 906 Z-score: 1071.1 E(): 9e-52 Smith-Waterman score: 906; 41.739 identity in 345 aa overlap ORF ftt0569c YP_169595.1 ORF ftt0570 YP_169596.1 Partially similar to Q96F61 Hypothetical protein from Homo sapiens (409 aa). FASTA: opt: 403 Z-score: 516.3 E(): 7.3e-21 Smith-Waterman score: 403; 34.171 identity in 199 aa overlap ORF ftt0571 YP_169597.1 Similar to Q8Z269 PTR2 family transport protein from Salmonella typhi (489 aa). FASTA: opt: 729 Z-score: 778.1 E(): 1.9e-35 Smith-Waterman score: 770; 30.524identity in 439 aa overlap ORF ftt0572 YP_169598.1 Similar to Q81EB9 Alanine racemase from Bacillus cereus (408 aa). FASTA: opt: 573 Z-score: 679.1 E(): 6.2e-30 Smith-Waterman score: 573; 29.863 identity in 365 aa overlap YP_169599.1 Similar to Q8KBW6 Prephenate dehydratase from chlorobium tepidum (280 aa). FASTA: opt: 624 Z-score: 792.7 E(): 2.9e-36 Smith-Waterman score: 624; 38.489 identity in 278 aa overlap YP_169600.1 Similar to Q894N2 zinc metallopeptidase from Clostridium tetani (236 aa). FASTA: opt: 434 Z-score: 526.0 E(): 2.1e-21 Smith-Waterman score: 434; 36.245 identity in 229 aa overlap ORF ftt0576 YP_169601.1 Similar to Q8EEW4 L-serine dehydratase 1 from Shewanella oneidensis (458 aa). FASTA: opt: 1442 Z-score: 1806.4 E(): 1e-92 Smith-Waterman score: 1442; 48.922 identity in 464 aa overlap YP_169602.1 Similar to Q8ZDZ4 selenocysteine lyase from Yersinia pestis (406 aa). FASTA: opt: 1343 Z-score: 1645.0 E(): 9.9e-84 Smith-Waterman score: 1343; 48.507 identity in 402 aa overlap YP_169603.1 Similar to AAP95950 HesB family protein from Haemophilus ducreyi (107 aa). FASTA: opt: 288 Z-score: 392.8 E(): 5.5e-14 Smith-Waterman score: 288; 41.121 identity in 107 aa overlap ORF ftt0579 YP_169604.1 Similar to Q83BY3 Hypothetical protein from Coxiella burnetii (180 aa). FASTA: opt: 593 Z-score: 750.6 E(): 6.4e-34 Smith-Waterman score: 593; 48.045 identity in 179 aa overlap ORF ftt0580 YP_169605.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_169606.1 ferredoxin. Identical to Q47937 Ferredoxin from Francisella novicida. Similar to Q88AH4 Ferredoxin from pseudomonas syringae (83 aa). FASTA: opt: 431 Z-score: 563.2 E(): 1.8e-23 Smith-Waterman score: 431; 65.432 identity in 81 aa overlap YP_169607.1 No transmembrane helix predicted. YP_169608.1 ORF ftt0584 YP_169609.1 Similar to Q9YCL9 Hypothetical protein APE1239 from Aeropyrum pernix (221 aa). FASTA: opt: 238 Z-score: 303.8 E(): 5e-09 Smith-Waterman score: 238; 25.683 identity in 183 aa overlap. Weakly conserved. ORF ftt0586 YP_169610.1 ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 transposase from Francisella tularensis (247 aa). YP_169611.1 Similar to AROA_VIBPA (Q87QX9) 3-phosphoshikimate 1-carboxyvinyltransferase from Vibrio parahaemolyticus (426 aa). FASTA: opt: 928 Z-score: 1157.4 E(): 1.4e-56 Smith-Waterman score: 928; 36.916 identity in 428 aa overlap YP_169612.1 ORF ftt0589 YP_169613.1 Similar to RNH_PSEAE (Q9I2S9) Ribonuclease H from Pseudomonas aeruginosa (148 aa). FASTA: opt: 673 Z-score: 830.4 E(): 2.3e-38 Smith-Waterman score: 673; 62.937 identity in 143 aa overlap YP_169614.1 Similar to Q8EEG1 L-asparaginase I from Shewanella oneidensis (337 aa). FASTA: opt: 1041 Z-score: 1293.4 E(): 3.7e-64 Smith-Waterman score: 1041; 49.258identity in 337 aa overlap YP_169615.1 Similar to Q87AM3 Carbonic anhydrase from xylella fastidiosa (220 aa). FASTA: opt: 577 Z-score: 733.9 E(): 5.5e-33 Smith-Waterman score: 722; 45.536 identity in 224 aa overlap YP_169616.1 ORF ftt0593c YP_169617.1 Similar to Q87N89 Hypothetical protein from Vibrio parahaemolyticus (344 aa). FASTA: opt: 706 Z-score: 859.6 E(): 5.5e-40 Smith-Waterman score: 706; 42.160 identity in 287 aa overlap ORF ftt0594c YP_169618.1 Similar to Q88C68 Rubredoxin from Pseudomonas putida (55 aa). FASTA: opt: 334 Z-score: 465.9 E(): 4.6e-18 Smith-Waterman score: 334; 78.431 identity in 51 aa overlap YP_169619.1 ORF ftt0596c YP_169620.1 Similar to Q9K5Z6 Hypothetical UPF0061 protein BH393 from Bacillus halodurans (492 aa). FASTA: opt: 1251 Z-score: 1519.2 E(): 1e-76 Smith-Waterman score: 1357; 48.233 identity in 481 aa overlap ORF ftt0597 YP_169621.1 Similar to Q8XLU3 Probable transmembrane symporter from Clostridium perfringens (435 aa). FASTA: opt: 881 Z-score: 961.9 E(): 1.1e-45 Smith-Waterman score: 881; 33.721identity in 430 aa overlap ORF ftt0598c YP_169622.1 Similar to Q9AAR1 SIS domain protein from Caulobacter crescentus (358 aa). FASTA: opt: 864 Z-score: 1052.1 E(): 1e-50 Smith-Waterman score: 864; 42.353 identity in 340 aa overlap. Glucosamine-fructose-6-phosphate aminotransferase ORF ftt0599 YP_169623.1 ORF ftt0601 YP_169624.1 ORF ftt0602c YP_169625.1 ORF ftt0603 YP_169626.1 Similar to Q9CNR2 NhaP NA+/H+ antiporter Conserved hypothetical membrane protein from Pasteurella multocida (441 aa). FASTA: opt: 315 Z-score: 391.3 E(): 6.6e-14 Smith-Waterman score: 315; 39.850 identity in 133 aa overlap. Matches to a central part of an Nhap protein ORF ftt0604 YP_169627.1 ORF ftt0605c YP_169628.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_169629.1 Similar to Q9KHC2 Hypothetical 27.0 kDa protein from secondary endosymbiont of Glycaspis brimblecombei (244 aa). FASTA: opt: 467 Z-score: 605.3 E(): 8e-26 Smith-Waterman score: 467; 44.751identity in 181 aa overlap ORF ftt0608 YP_169630.1 Similar to Q83F75 Peptidase, M24 family protein from Coxiella burnetii (597 aa). FASTA: opt: 1665 Z-score: 1963.9 E(): 1.7e-101 Smith-Waterman score: 1665; 45.286 identity in 594 aa overlap ORF ftt0609 YP_169631.1 Similar to Q8DFB3 DNA/RNA endonuclease G from Vibrio vulnificus (247 aa). FASTA: opt: 682 Z-score: 838.7 E(): 8e-39 Smith-Waterman score: 682; 46.311 identity in 244 aa overlap ORF ftt0610 YP_169632.1 Similar to Q9L6I3 Extended-spectrum beta-lactamase BES-1 from Serratia marcescens (292 aa).FASTA: opt: 621 Z-score: 723.1 E(): 2.2e-32 Smith-Waterman score: 621; 34.397 identity in 282 aa overlap ORF ftt0611c YP_169633.1 ORF ftt0612 YP_169634.1 This ORF is longer. ORF ftt0613c YP_169635.1 Similar to Q820B4 Apolipoprotein N-acyltransferase from Coxiella burnetii (485 aa). FASTA: opt: 984 Z-score: 1082.0 E(): 2.2e-52 Smith-Waterman score: 984; 35.903 identity in 493 aa overlap ORF ftt0614c YP_169636.1 Similar to Q8EHP0 Magnesium and cobalt efflux protein CorC from Shewanella oneidensis (291 aa). FASTA: opt: 676 Z-score: 772.4 E(): 3.9e-35 Smith-Waterman score: 676; 39.847 identity in 261 aa overlap ORF ftt0615c YP_169637.1 Similar to Q8EHN9 Hypothetical UPF0054 protein SO117 from Shewanella oneidensis (153 aa). FATSA: opt: 433 Z-score: 547.4 E(): 1.3e-22 Smith-Waterman score: 433; 44.025identity in 159 aa overlap ORF ftt0616c YP_169638.1 Simliar to Q87VY0 PhoH-like protein from Pseudomonas syringae (340 aa). FASTA: opt: 1132 Z-score: 1306.4 E(): 7.1e-65 Smith-Waterman score: 1132; 52.923 identity in 325 aa overlap YP_169639.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_169640.1 Similar to O67476 O-methyltransferase from Aquifex aeolicus (212 aa). FASTA: opt: 382 Z-score: 477.6 E(): 1e-18 Smith-Waterman score: 382; 33.495 identity in 206 aa overlap. ORF ftt0619 YP_169641.1 Similar to Q8PER3 Acid phosphatase from Xanthomonas axonopodis (310 aa). FASTA: opt: 238 Z-score: 293.2 E(): 1.9e-08 Smith-Waterman score: 238; 24.583 identity in 240 aa overlap. ORF ftt0620 YP_169642.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_169643.1 ORF ftt0622c YP_169644.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_169645.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_169646.1 binds and unfolds substrates as part of the ClpXP protease YP_169647.1 Similar to Q8Z8V0 Lon protease from Salmonella typhi (784 aa). FASTA: opt: 2734 Z-score: 2797.3 E(): 6.4e-148 Smith-Waterman score: 2734; 54.450 identity in 764 aa overlap. YP_169648.1 Similar to Q93TM3 Histone-like protein HU form B from Pseudomonas putida (strain KT2440) (90 aa). FASTA: opt: 380 Z-score: 519.0 E(): 5.2e-21 Smith-Waterman score: 380; 68.539 identity in 89 aa overlap. YP_169649.1 Similar to PPID_BUCAP (Q8K987) Peptidyl-prolyl cis-trans isomerase from Buchnera aphidicola (subsp. Schizaphis graminum) (621 aa). FASTA: opt: 298 Z-score: 309.1E(): 2.5e-09 Smith-Waterman score: 298; 23.362 identity in 351 aa overlap. 200 aa shorter (in C-term) than most of the homologs. ORF ftt0628 YP_169650.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_169651.1 Similar to HFQ_PASMU (Q9CMC6) Hfq protein from Pasteurella multocida (95 aa). FASTA: opt: 384 Z-score: 504.4 E(): 3.3e-20 Smith-Waterman score: 384; 68.182 identity in 88 aa overlap. Plays a role in degradation of RNA transcripts. YP_169652.1 Similar to Q87VJ5 GTP-binding protein HflX from Pseudomonas syringae (pv. tomato) (433 aa). FASTA: opt: 1331 Z-score: 1520.3 E(): 8.6e-77 Smith-Waterman score: 1331; 49.302 identity in 430 aa overlap. Together with HflC-HflK involved in stability of phage lambda cII repressor YP_169653.1 Similar to O53772 oxidoreductase (Monooxygenase) from Mycobacterium tuberculosis (388 aa). FASTA: opt: 832 Z-score: 997.9 E(): 1.1e-47 Smith-Waterman score: 832; 35.550 identity in 391 aa overlap. ORF ftt0632c YP_169654.1 Similar to Q8FAK7 HflK protein from Escherichia coli (419 aa). FASTA: opt: 843 Z-score: 932.9 E(): 4.5e-44 Smith-Waterman score: 843; 40.0 identity in 330 aa overlap. With HflC, part of modulator for protease specific for FtsH phage lambda cII repressor. YP_169655.1 Similar to Q8EJ66 HflC protein from Shewanella oneidensis (297 aa). FASTA: opt: 799 Z-score: 895.3 E(): 5.6e-42 Smith-Waterman score: 799; 42.466 identity in 292 aa overlap. With HflK, part of modulator for protease specific for FtsH phage lambda cII repressor. YP_169656.1 Similar to O35016 YFKJ protein from Bacillus subtilis (156 aa). FASTA: opt: 391 Z-score: 494.5 E(): 1.2e-19 Smith-Waterman score: 391; 38.608 identity in 158 aa overlap. YP_169657.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_169658.1 fragment. Weak similarity to leuA LE12_METJA (Q58595) 2-isopropylmalate synthase 2 from Methanococcus jannaschii (518 aa). FASTA: opt: 119 Z-score: 151.8 E(): 1.5 Smith-Waterman score: 119; 26.316 identity in 114 aa overlap (6-115:356-467). Next downstream ORF also has similarity to leuA. ORF ftt0638 YP_169659.1 fragment. Weak similarity to leuA LE12_METJA (Q58595) 2-isopropylmalate synthase 2 from Methanococcus jannaschii (518 aa). FASTA: opt: 86 Z-score: 142.0 E(): 5.1 Smith-Waterman score: 86; 50.000 identity in 32 aa overlap (1-32:479-510). Next upstream ORF also have similarity to leuA. ORF ftt0639 YP_169660.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_169661.1 Similar to Q8A610 Acetohydroxyacid synthase small subunit (187 aa). FASTA: opt: 159 Z-score: 221.3 E(): 0.0002 Smith-Waterman score: 159; 33.333 identity in 75 aa overlap. YP_169662.1 Similar to Q9CM06 Mfd from Pasteurella multocida (1145 aa). FASTA: opt: 3312 Z-score: 3697.7 E(): 4.5e-198 Smith-Waterman score: 3312; 44.794 identity in 1143 aa overlap. YP_169663.1 Similar to YCCA_ECOLI (P06967) Hypothetical protein yccA from Escherichia coli (219 aa). FASTA: opt: 588 Z-score: 603.2 E(): 1.1e-25 Smith-Waterman score: 588; 48.416 identity in 221 aa overlap. ORF ftt0645c YP_169664.1 ORF ftt0646c YP_169665.1 Similar to Q82WE7 Hypothetical protein from Nitrosomonas europaea (164 aa). FASTA: opt: 383 Z-score: 490.4 E(): 2e-19 Smith-Waterman score: 383; 41.606 identity in 137 aa overlap. ORF ftt0647c YP_169666.1 Similar to Q9HYB4 Endonuclease III from Pseudomonas aeruginosa (212 aa). FASTA: opt: 916 Z-score: 1153.9 E(): 2.2e-56 Smith-Waterman score: 916; 67.308identity in 208 aa overlap. YP_169667.1 Similar to Q83B23 4Fe-4S binding domain protein from Coxiella burnetii (213 aa). FASTA: opt: 552 Z-score: 680.7 E(): 5e-30 Smith-Waterman score: 552; 42.788 identity in 208 aa overlap. YP_169668.1 cofactor involved in the reduction of disulfides YP_169669.1 Similar to Q9L9P6 IraB from Legionella pneumophila (501 aa). FASTA: opt: 1486 Z-score: 1640.1 E(): 1.8e-83 Smith-Waterman score: 1486; 46.708 identity in 486 aa overlap. ORF ftt0651 YP_169670.1 Similar to Q899N4 Ferritin from Clostridium tetani (169 aa). FASTA: opt: 527 Z-score: 679.5 E(): 5.9e-30 Smith-Waterman score: 527; 45.783identity in 166 aa overlap. YP_169671.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_169672.1 Similar to Q87IN9 Sigma cross-reacting protein 27A from Vibrio parahaemolyticus (216 aa). FASTA: opt: 683 Z-score: 873.4 E(): 9.3e-41 Smith-Waterman score: 683; 49.074 identity in 216 aa overlap. YP_169673.1 Similar to YO32_SHEON (Q8EEF0) Hypothetical UPF0082 protein SO2432 from Shewanella oneidensis (248 aa). FASTA: opt: 1090 Z-score: 1308.8 E(): 5.2e-65 Smith-Waterman score: 1090; 64.516 identity in 248 aa overlap. ORF ftt0655 YP_169674.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_169675.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_169676.1 Similar to Q87TH5 Conserved hypothetical protein from Vibrio parahaemolyticus (514 aa). FASTA: opt: 1129 Z-score: 1083.4 E(): 1.9e-52 Smith-Waterman score: 1132; 42.000 identity in 450 aa overlap ORF ftt0659 YP_169677.1 ORF ftt0660 YP_169678.1 Similar to Q82LF3 Hypothetical protein from Streptomyces avermitilis (109 aa). FASTA: opt: 260 Z-score: 364.1 E(): 2.2e-12 Smith-Waterman score: 260; 47.778 identity in 90 aa overlap. The homologs are of different sizes. ORF ftt0661c YP_169680.1 ORF ftt0663 YP_169681.1 catalyzes the formation of histamine from L-histidine YP_169682.1 Similar to Q88IX8 Class II aldolase/adducin domain protein from Pseudomonas putida (strain KT2440) (251 aa). FASTA: opt: 472 Z-score: 599.3 E(): 1.7e-25 Smith-Waterman score: 472; 38.579identity in 197 aa overlap. ORF ftt0665c YP_169683.1 Similar to Q896H4 DNA-3-methyladenine glycosylase from Clostridium tetani (203 aa). FASTA: opt: 451 Z-score: 589.0 E(): 6.4e-25 Smith-Waterman score: 451; 42.784 identity in 194 aa overlap. ORF ftt0666c YP_169684.1 ORF ftt0667 YP_169685.1 Similar to Q8A546 membrane transporter involved in nicotinamide mononucleotide transport from Bacteroides thetaiotaomicron (188 aa). FASTA: opt: 333 Z-score: 403.8 E(): 1.3e-14 Smith-Waterman score: 333; 29.016identity in 193 aa overlap. ORF ftt0668 YP_169686.1 Similar to Q8GRF6 MagA protein from Magnetospirillum magnetotacticum (Aquaspirillum magnetotacticum) (432 aa). FASTA: opt: 769 Z-score: 826.0 E(): 4.1e-38 Smith-Waterman score: 769; 31.635identity in 373 aa overlap. ORF ftt0669 YP_169687.1 ORF ftt0670c YP_169688.1 Similar to Q83DX6 Major facilitator family transporter from Coxiella burnetii (421 aa). FASTA: opt: 689 Z-score: 731.9 E(): 7.1e-33 Smith-Waterman score: 689; 29.197identity in 411 aa overlap. ORF ftt0671 YP_169689.1 Similar to Q8DF84 Predicted deacylase from Vibrio vulnificus (352 aa). FASTA: opt: 789 Z-score: 951.5 E(): 4.2e-45 Smith-Waterman score: 789; 34.328 identity in 335 aa overlap. ORF ftt0673c YP_169690.1 Similar to KPRS_RALSO (Q8Y2E1) Ribose-phosphate pyrophosphokinase from Ralstonia solanacearum (Pseudomonas solanacearum) (316 aa). FASTA: opt: 1269 Z-score: 1520.3 E(): 8.6e-77 Smith-Waterman score: 1269; 58.413 identity in 315 aa overlap. YP_169691.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_169692.1 Similar to Q83E77 Hypothetical protein from Coxiella burnetii (417 aa). FASTA: opt: 1049 Z-score: 1211.5 E(): 1.4e-59 Smith-Waterman score: 1049; 40.049 identity in 407 aa overlap. ORF ftt0676 YP_169693.1 Similar to Q8Z984 methyltransferase from Salmonella typhi (256 aa). FASTA: opt: 707 Z-score: 818.1 E(): 1.1e-37 Smith-Waterman score: 707; 42.570 identity in 249 aa overlap. ORF ftt0677c YP_169694.1 ORF ftt0678c YP_169695.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_169696.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_169697.1 Similar to BLAC_YEREN (Q01166) Beta-lactamase precursor from Yersinia enterocolitica (294 aa). FASTA: opt: 670 Z-score: 829.7 E(): 2.5e-38 Smith-Waterman score: 670; 36.268 identity in 284 aa overlap. YP_169698.1 ORF ftt0682c YP_169699.1 Similar to Q888U2 Type IV pilus prepilin peptidase PilD from Pseudomonas syringae (pv. tomato) (290 aa). FASTA: opt: 784 Z-score: 898.0 E(): 4e-42 Smith-Waterman score: 784; 44.531identity in 256 aa overlap. Cleaves the leader peptide of the fiber building block proteins and methylates the resulting N-terminal residue. YP_169700.1 catalyzes the conversion of NADPH to NADH YP_169701.1 Similar to KCH_ECOLI (P31069) potassium channel protein (417 aa). FASTA: opt: 381 Z-score: 423.3 E(): 1.1e-15 Smith-Waterman score: 381; 31.203identity in 266 aa overlap. ORF ftt0685c YP_169702.1 Similar to Q83E30 Proton/peptide symporter family protein from Coxiella burnetii (492 aa). FASTA: opt: 609 Z-score: 644.8 E(): 5e-28 Smith-Waterman score: 609; 26.545 identity in 437 aa overlap. The start is approx 55 aa later than the homologs. ORF ftt0686c YP_169703.1 heat shock protein involved in degradation of misfolded proteins YP_169704.1 heat shock protein involved in degradation of misfolded proteins YP_169705.1 ORF ftt0689 YP_169706.1 Similar to Q9KS71 Lipoate-protein ligase A from Vibrio cholerae (338 aa). FASTA: opt: 699 Z-score: 831.1 E(): 2.1e-38 Smith-Waterman score: 699; 38.545identity in 275 aa overlap. YP_169707.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_169708.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169709.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_169710.1 Similar to AAP18158 2-acyl-glycerophospho-ethanolamine acyltransferase,acyl-acyl-carrier protein synthetase from Shigella flexneri (719 aa). FASTA: opt: 735 Z-score: 862.5 E(): 3.8e-40 Smith-Waterman score: 826; 33.661identity in 508 aa overlap. n. b. No match between aa 1 and 196. Several domains missing compared to AAP18158 ORF ftt0694 YP_169711.1 Similar to AAP95225 S-adenosyl-methyltransferase MraW from Haemophilus ducreyi (313 aa). FASTA: opt: 918 Z-score: 1107.1 E(): 8.9e-54 Smith-Waterman score: 918; 49.677identity in 310 aa overlap. YP_169712.1 Weak similarity to cell division protein ftsL. ORF ftt0696 YP_169713.1 Similar to Q83F33 Penicillin-binding protein 3 from Coxiella burnetii (548 aa). FASTA: opt: 1361 Z-score: 1597.9 E(): 4.1e-81 Smith-Waterman score: 1361; 40.325 identity in 553 aa overlap. YP_169714.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_169715.1 Similar to Q83D87 Polyribonucleotide nucleotidyltransferase from Coxiella burnetii (696 aa). FASTA: opt: 2437 Z-score: 2800.2 E(): 4.4e-148 Smith-Waterman score: 2437; 54.401identity in 693 aa overlap. YP_169716.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_169717.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_169718.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_169719.1 Similar to RPOZ_PSEPK (Q88C82) Probable DNA-directed RNA polymerase omega chain from Pseudomonas putida (strain KT2440) (87 aa). FASTA: opt: 194 Z-score: 293.6 E(): 1.8e-08 Smith-Waterman score: 194; 52.857 identity in 70 aa overlap. YP_169720.1 ORF ftt0704 YP_169721.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_169722.1 Similar to Q9CK00 Hypothetical protein PM1838 from Pasteurella multocida (234 aa). FASTA: opt: 456 Z-score: 507.2 E(): 2.3e-20 Smith-Waterman score: 456; 34.483identity in 232 aa overlap. ORF ftt0707 YP_169723.1 Similar to Q83BD8 Major facilitator family transporter from Coxiella burnetii (411 aa). FASTA: opt: 868 Z-score: 941.6 E(): 1.5e-44 Smith-Waterman score: 868; 37.912identity in 364 aa overlap. ORF ftt0708 YP_169724.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_169725.1 Similar to FTSB_VIBPA (Q87LQ1) Cell division protein ftsB homolog from Vibrio parahaemolyticus (93 aa). FASTA: opt: 198 Z-score: 273.8 E(): 2.3e-07 Smith-Waterman score: 198; 37.209 identity in 86 aa overlap. YP_169726.1 Similar to ISPD_PASMU (P57953) 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (238 aa). FASTA: opt: 506 Z-score: 656.8 E(): 1.1e-28 Smith-Waterman score: 506; 39.381 identity in 226 aa overlap. YP_169727.1 Similar to SDAC_HAEIN (P44615) Serine transporter from Haemophilus influenzae (412 aa). FASTA: opt: 785 Z-score: 854.1 E(): 1.1e-39 Smith-Waterman score: 785; 33.099 identity in 426 aa overlap. YP_169728.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_169729.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_169730.1 Similar to Q9ZIX2 Chitinase c from Pseudoalteromonas sp. S9 (869 aa). FASTA: opt: 331 Z-score: 370.4 E(): 9.6e-13 Smith-Waterman score: 583; 24.111 identity in 900 aa overlap. The homologs are of varying sizes. ORF ftt0715 YP_169731.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_169732.1 ORF ftt0718 YP_169733.1 Aa 139-320 identical to AAP97846 Hypothetical protein (Fragment) from Francisella tularensis ssp. tularensis strain SchuS4 (184 aa). Similar to Q881T0 Proline/betaine transporter from Pseudomonas syringae (pv. tomato) (438 aa). FASTA: opt: 561 Z-score: 633.8 E(): 2.1e-27 Smith-Waterman score: 561; 25.616 identity in 406 aa overlap. ORF ftt0719 YP_169734.1 Similar to DGT1_VIBPA (Q87R73) Deoxyguanosinetriphosphate triphosphohydrolase-like protein from Vibrio parahaemolyticus (440 aa). FASTA: opt: 587 Z-score: 683.8 E(): 3.4e-30 Smith-Waterman score: 661; 33.781identity in 447 aa overlap. YP_169735.1 Similar to CATA_YERPE (Q9X6B0) Peroxidase/catalase (EC 1.11.1.6) from Yersinia pestis (737 aa). FASTA: opt: 3041 Z-score: 3508.0 E(): 1.7e-187 Smith-Waterman score: 3041; 59.189 identity in 740 aa overlap. YP_169736.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169737.1 Similar to Q88H18 Oxidoreductase, short chain dehydrogenase/reductase family Pseudomonas putida (strain KT2440) (248 aa). FASTA: opt: 792 Z-score: 881.9 E(): 3.1e-41 Smith-Waterman score: 792; 47.984 identity in 248 aa overlap. ORF ftt0723c YP_169738.1 Similar to Q81V41 Glycerol-3-phosphate transporter from Bacillus anthracis (strain Ames) (449 aa). FASTA: opt: 1382 Z-score: 1521.3 E(): 7.6e-77 Smith-Waterman score: 1382; 48.268identity in 433 aa overlap. YP_169739.1 Similar to Q89FW5 Blr6584 protein from Bradyrhizobium japonicum (342 aa). FASTA: opt: 636 Z-score: 743.1 E(): 1.7e-33 Smith-Waterman score: 743; 36.336identity in 333 aa overlap. ORF ftt0726c YP_169741.1 Similar to Q89II5 ABC transporter ATP-binding protein (310 aa). FASTA: opt: 1060 Z-score: 1223.8 E(): 2.8e-60 Smith-Waterman score: 1060; 54.605 identity in 304 aa overlap. YP_169742.1 Similar to Q8Y316 Probable transmembrane protein from Ralstonia solanacearum (Pseudomonas solanacearum) (381 aa). FASTA: opt: 1138 Z-score: 1260.3 E(): 2.6e-62 Smith-Waterman score: 1138; 45.722 identity in 374 aa overlap. YP_169743.1 ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 transposase from Francisella tularensis (247 aa). YP_169745.1 ORF ftt0732 YP_169746.1 Similar to Q9A7J3 Glutathione peroxidase from Caulobacter crescentus (160 aa). FASTA: opt: 605 Z-score: 801.1 E(): 9.9e-37 Smith-Waterman score: 605; 55.696 identity in 158 aa overlap. ORF ftt0733 YP_169747.1 Similar to Q8REM4 Hypothetical protein FN1075 (215 aa). FASTA: opt: 221 Z-score: 288.5 E(): 3.5e-08 Smith-Waterman score: 221; 25.463identity in 216 aa overlap. ORF ftt0736 YP_169748.1 ORF ftt0737c YP_169749.1 Similar to Q82Y67 Possible sugar kinase from Nitrosomonas europaea (505 aa). FASTA: Z-score: 922.3 E(): 1.8e-43 Smith-Waterman score: 856; 35.529 identity in 501 aa overlap. YP_169750.1 Similar to Q88AZ6 Heat shock protein 15 from Pseudomonas syringae (pv. tomato) (135 aa). FASTA: Z-score: 549.3 E(): 1.1e-22 Smith-Waterman score: 447; 58.824 identity in 119 aa overlap. YP_169753.1 ORF ftt0742 YP_169754.1 Similar to Q87Q96 Conserved hypothetical protein from Vibrio parahaemolyticus (274 aa). FASTA: opt: 950 Z-score: 1132.9 E(): 3.3e-55 Smith-Waterman score: 950; 49.259 identity in 270 aa overlap. ORF ftt0743 YP_169758.1 Similar to Q88NQ3 Membrane fusion protein, (289 aa). FASTA: opt: 721 Z-score: 853.4 E(): 1.2e-39 Smith-Waterman score: 721; 41.434identity in 251 aa overlap. Similar to ydhJ and yhcQ in E. coli. ORF ftt0747c YP_169759.1 Similar to Q93PU6 regulatory protein TtgV from Pseudomonas putida (259 aa). FASTA: opt: 485 Z-score: 588.0 E(): 7.4e-25 Smith-Waterman score: 485; 33.473 identity in 239 aa overlap. ORF ftt0748 YP_169760.1 Aa 8-183 identical to AAP97845 Hypothetical protein (Fragment) from Francisella tularensis ssp. tularensis strain SchuS4 (176 aa). Similar to Q8CL71 Hypothetical from Yersinia pestis (311 aa). FASTA: opt: 842 Z-score: 992.9 E(): 2e-47 Smith-Waterman score: 842; 44.710 identity in 293 aa overlap ORF ftt0749c YP_169761.1 Similar to Q83AM1 Radical SAM domain protein from Coxiella burnetii (342 aa). FASTA: opt: 1094 Z-score: 1304.2 E(): 9.4e-65 Smith-Waterman score: 1094; 48.930 identity in 327 aa overlap. ORF ftt0750 YP_169762.1 Similar to Q89UH2 Cold shock protein from Bradyrhizobium japonicum (70 aa). FASTA: opt: 297 Z-score: 443.7 E(): 8e-17 Smith-Waterman score: 297; 66.176 identity in 68 aa overlap. YP_169764.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_169765.1 ORF ftt0754c YP_169766.1 ORF ftt0755 YP_169767.1 Similar to Q83BX5 Cation-efflux family protein from Coxiella burnetii (378 aa). FASTA: opt: 773 Z-score: 908.9 E(): 9.8e-43 Smith-Waterman score: 774; 34.605 identity in 367 aa overlap. ORF ftt0756 YP_169768.1 Similar to Q9K0G7 UTP--glucose-1-phosphate uridylyltransferase from Neisseria meningitidis (serogroup B) (289 aa). FASTA: opt: 1017 Z-score: 1291.1 E(): 5e-64 Smith-Waterman score: 1017; 57.439 identity in 289 aa overlap. YP_169769.1 Similar to YYAM_BACSU (P37511) Hypothetical transport protein yyaM from Bacillus subtilis (305 aa). FASTA: opt: 402 Z-score: 452.6 E(): 2.6e-17 Smith-Waterman score: 402; 25.614 identity in 285 aa overlap. ORF ftt0759 YP_169770.1 ORF ftt0760c YP_169771.1 ORF ftt0761c YP_169772.1 Similar to RECF_PROMI (P22839) DNA replication and repair protein from Proteus mirabilis (362 aa). FASTA: opt: 874 Z-score: 1010.7 E(): 2.1e-48 Smith-Waterman score: 874; 37.394 identity in 353 aa overlap. YP_169773.1 Similar to YJJV_ECOLI (P39408) deoxyribonuclease yjjV (259 aa). FASTA: opt: 503 Z-score: 595.3 E(): 2.9e-25 Smith-Waterman score: 503; 31.048 identity in 248 aa overlap. YP_169774.1 Similar to SYGB_COXBU (P45651) Glycyl-tRNA synthetase beta chain from Coxiella burnetii (689 aa). FASTA: opt: 1810 Z-score: 2108.8 E(): 1.4e-109 Smith-Waterman score: 1810; 42.939 identity in 694 aa overlap. YP_169775.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169776.1 Similar to Q9PQL0 Purine-nucleoside phosphorylase from Ureaplasma parvum (Ureaplasma urealyticum biotype 1) (239 aa). FASTA: opt: 697 Z-score: 837.2 E(): 9.7e-39 Smith-Waterman score: 697; 47.534 identity in 223 aa overlap. YP_169777.1 ORF ftt0767c YP_169778.1 ORF ftt0768c YP_169779.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_169780.1 Similar to AAP95195 50S ribosomal protein L21 from Haemophilus ducreyi (103 aa). FASTA: opt: 435 Z-score: 570.3 E(): 7.1e-24 Smith-Waterman score: 435; 66.019 identity in 103 aa overlap. YP_169781.1 involved in the peptidyltransferase reaction during translation YP_169782.1 Similar to Q8DJY4 Tll1086 protein from Synechococcus elongatus (Thermosynechococcus elongatus) (126 aa). FASTA: opt: 516 Z-score: 715.9 E(): 5.5e-32 Smith-Waterman score: 516; 64.348 identity in 115 aa overlap. ORF ftt0774 YP_169783.1 Similar to Q8YGF6 Ribonuclease D from Brucella melitensis (385 aa). FASTA: opt: 538 Z-score: 584.5 E(): 1.2e-24 Smith-Waterman score: 538; 28.919 identity in 370 aa overlap. YP_169784.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_169785.1 ORF ftt0778 YP_169786.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169787.1 ORF ftt0780c YP_169788.1 Similar to Q82UL5 Hypothetical protein from Nitrosomonas europaea (239 aa). FASTA: opt: 736 Z-score: 920.8 E(): 2.1e-43 Smith-Waterman score: 736; 54.680 identity in 203 aa overlap. The family of possible lysine decarboxylase proteins shares a highly conserved motif PGGXGTXXE that is probably functionally important. This protein has that motif. ORF ftt0781c YP_169789.1 Similar to Q87YS1 Enoyl-(acyl-carrier-protein) reductase from Pseudomonas syringae (pv. tomato) (264 aa). FASTA: opt: 1071 Z-score: 1313.1 E(): 3e-65 Smith-Waterman score: 1071; 62.595 identity in 262 aa overlap. YP_169790.1 Similar to Q9CPJ8 Arylsulfatase from Pasteurella multocida (327 aa). FASTA: opt: 544 Z-score: 669.4 E(): 2.2e-29 Smith-Waterman score: 544; 31.420 identity in 331 aa overlap. YP_169791.1 ORF ftt0784 YP_169792.1 Similar to Q88K93 Conserved hypothetical protein (277 aa). FASTA: opt: 718 Z-score: 855.8 E(): 8.9e-40 Smith-Waterman score: 718; 42.308identity in 260 aa overlap. ORF ftt0785 YP_169793.1 ORF ftt0786 YP_169794.1 Similar to Q8EDN3 Conserved hypothetical protein from Shewanella oneidensis (197 aa). FASTA: opt: 435 Z-score: 540.9 E(): 3.1e-22 Smith-Waterman score: 435; 42.935 identity in 184 aa overlap. ORF ftt0787 YP_169795.1 Similar to Q8KLW6 Hypothetical protein from Pseudomonas stutzeri (Pseudomonas perfectomarina) (324 aa). FASTA: opt: 1095 Z-score: 1307.1 E(): 6.5e-65 Smith-Waterman score: 1095; 54.489 identity in 323 aa overlap. Homologs are involved in sialic acid capsule biosynthesis in some pathogenic strains of Escherichia coli. YP_169796.1 Similar to Q8EK14 Ribulose-phosphate 3-epimerase (225 aa). FASTA: opt: 953 Z-score: 1164.4 E(): 5.8e-57 Smith-Waterman score: 953; 65.766identity in 222 aa overlap. YP_169797.1 Similar to Q9FDJ5 glycosyltransferase from Lactobacillus rhamnosus (466 aa). FASTA: opt: 733 Z-score: 876.0 E(): 6.7e-41 Smith-Waterman score: 733; 33.333 identity in 399 aa overlap. ORF ftt0790 YP_169799.1 Similar to Q9HTC0 Glycosyltransferase WbpZ from Pseudomonas aeruginosa (381 aa). FASTA: opt: 621 Z-score: 721.7 E(): 2.6e-32 Smith-Waterman score: 1019; 38.725 identity in 408 aa overlap. ORF ftt0792 YP_169800.1 Similar to Q8DMA7 ATP-binding protein of ABC transporter from Synechococcus elongatus (Thermosynechococcus elongatus) (610 aa). FASTA: opt: 1084 Z-score: 1105.1 E(): 1.2e-53 Smith-Waterman score: 1084; 35.159 identity in 566 aa overlap. ORF ftt0793 YP_169801.1 Similar to AAP76675 Phosphoserine phosphatase from Helicobacter hepaticus (199 aa). FASTA: opt: 751 Z-score: 908.2 E(): 1.1e-42 Smith-Waterman score: 751; 55.385 identity in 195 aa overlap (18-212:4-198) AND to AAP76674 Hypothetical protein from Helicobacter hepaticus (213 aa). FASTA: opt: 823 Z-score: 994.3 E(): 1.7e-47 Smith-Waterman score: 823; 57.212 identity in 208 aa overlap (221-428:6-213). Seems to be two genes in some organisms. ORF ftt0794 YP_169802.1 Similar to AAP76671 Hypothetical protein cfa from Helicobacter hepaticus (210 aa). FASTA: opt: 627 Z-score: 745.4 E(): 1.3e-33 Smith-Waterman score: 627; 44.660 identity in 206 aa overlap. ORF ftt0795 YP_169803.1 ORF ftt0796 YP_169804.1 Similar to O85000 Galactosyl transferase from Streptococcus pneumoniae (323 aa). FASTA: opt: 577 Z-score: 682.7 E(): 3.9e-30 Smith-Waterman score: 577; 40.171 identity in 234 aa overlap. Same homolog as for next downstream ORF. ORF ftt0797 YP_169805.1 Similar to O85000 Galactosyl transferase from Streptococcus pneumoniae (323 aa). FASTA: opt: 499 Z-score: 609.1 E(): 4.9e-26 Smith-Waterman score: 499; 34.454 identity in 238 aa overlap. Same homolog as for next upstream ORF. ORF ftt0798 YP_169806.1 Similar to Q00481 Second mannosyl transferase from Salmonella enterica (336 aa). FASTA: opt: 651 Z-score: 775.2 E(): 2.7e-35 Smith-Waterman score: 651; 35.455 identity in 330 aa overlap. ORF ftt0799 YP_169807.1 Similar to Q8FV27 Hydrolase, haloacid dehalogenase-like family from Brucella suis (234 aa). FASTA: opt: 422 Z-score: 503.3 E(): 3.8e-20 Smith-Waterman score: 422; 33.486identity in 218 aa overlap. ORF ftt0800 YP_169808.1 Similar to Q9YG89 310AA long hypothetical sugar kinase from Aeropyrum pernix (310 aa). FASTA: opt: 245 Z-score: 292.6 E(): 2.1e-08 Smith-Waterman score: 311; 25.795 identity in 283 aa overlap. ORF ftt0801c YP_169809.1 Similar to CPHB_SYNY8 (P56946) Cyanophycinase from Synechocystis sp. (strain PCC 6308) (272 aa). FASTA: opt: 701 Z-score: 857.3 E(): 7.4e-40 Smith-Waterman score: 701; 41.667 identity in 264 aa overlap. YP_169810.1 Similar to Q9ABX3 Asparaginase family protein from Caulobacter crescentus (292 aa). FASTA: 146 opt: 465 Z-score: 567.7 E(): 1e-23 Smith-Waterman score: 465; 35.606 identity in 264 aa overlap. YP_169811.1 Similar to O54543 (O54543) CITA from Legionella pneumophila (418 aa). FASTA: opt: 905 Z-score: 915.1 E(): 4.5e-43 Smith-Waterman score: 905; 33.254 identity in 418 aa overlap. ORF ftt0804 YP_169812.1 Similar to CAD71904 Capsule biosynthesis protein CapB from Rhodopirellula baltica (441 aa). FASTA: opt: 1155 Z-score: 1414.5 E(): 6.8e-71 Smith-Waterman score: 1156; 46.763 identity (50.914 ungapped) in 417 aa overlap. YP_169813.1 Similar to Q8REZ4 CapC protein from Fusobacterium nucleatum (152 aa). FASTA: opt: 360 Z-score: 420.9 E(): 1.5e-15 Smith-Waterman score: 360; 35.616 identity in 146 aa overlap. YP_169814.2 Similar to CAD71902 Hypothetical protein from Rhodopirellula baltica (404 aa). FASTA: opt: 477 Z-score: 563.9 E(): 1.6e-23 Smith-Waterman score: 553; 31.633 identity in 392 aa overlap. ORF ftt0807 YP_169815.1 Similar to SPOT_ECOLI Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase from Escherichia coli (702 aa). FASTA: opt: 1849 Z-score: 2107.7 E(): 1.7e-109 Smith-Waterman score: 1849; 41.210 identity in 711 aa overlap. YP_169816.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_169817.1 Similar to YBAB_ECOLI Hypothetical UPF0133 protein ybaB from Escherichia coli (109 aa). FASTA: opt: 332 Z-score: 403.8 E(): 1.3e-14 Smith-Waterman score: 332; 49.074identity in 108 aa overlap. YP_169818.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_169819.1 Similar to GCS1_SULTO Probable glycine cleavage system H from Sulfolobus tokodaii (142 aa). FASTA: opt: 397 Z-score: 525.8 E(): 2.1e-21 Smith-Waterman score: 397; 43.089 identity in 123 aa overlap. YP_169820.1 ORF ftt0813 YP_169824.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_169825.1 Similar to IF3_ECOLI Translation initiation factor IF-3 from Escherichia coli (180 aa). FASTA: opt: 674 Z-score: 836.1 E(): 1.1e-38 Smith-Waterman score: 674; 64.103 identity in 156 aa overlap. YP_169826.1 Similar to RL35_ECOLI 50S ribosomal protein L35 from Escherichia coli (64 aa). FASTA: opt: 247 Z-score: 385.9 E(): 1.3e-13 Smith-Waterman score: 247; 62.500 identity in 64 aa overlap. YP_169827.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_169828.1 Similar to Q9KRB9 Hypothetical protein VC1723 from Vibrio cholerae (229 aa). FASTA: opt: 344 Z-score: 394.7 E(): 4.3e-14 Smith-Waterman score: 344; 29.075 identity in 227 aa overlap. ORF ftt0821 YP_169829.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169830.1 Similar to Q9K8B7 Mutator MutT protein from Bacillus halodurans (207 aa). FASTA: opt: 413 Z-score: 505.4 E(): 2.9e-20 Smith-Waterman score: 413; 36.649identity in 191 aa overlap. ORF ftt0823 YP_169831.1 Similar to Q8CPW9 Arsenate reductase from Staphylococcus epidermidis (117 aa). FASTA: opt: 276 Z-score: 376.2 E(): 4.6e-13 Smith-Waterman score: 276; 32.759 identity in 116 aa overlap. YP_169832.1 hypothetical lipoprotein, no significant homologs. ORF ftt0825c YP_169833.1 ORF ftt0826c YP_169834.1 Similar to YIEG_ECOLI Hypothetical protein yieG from Escherichia coli (445 aa). FASTA: opt: 945 Z-score: 1037.7 E(): 6.6e-50 Smith-Waterman score: 945; 34.633 identity in 436 aa overlap. ORF ftt0827c YP_169835.1 Similar to Q845W9 Aspartate:alanine antiporter from Pseudomonas dacunhae (561 aa). FASTA: opt: 1359 Z-score: 1502.2 bits: 287.8 E(): 8.8e-76 Smith-Waterman score: 1359; 38.351 identity in 558 aa overlap. ORF ftt0829c YP_169836.1 Weakly similar to Q8A8H3 Outer membrane protein,OmpA family from Bacteroides thetaiotaomicron (266 aa). FASTA: opt: 184 Z-score: 220.7 E(): 0.00021 Smith-Waterman score: 184; 29.299 identity in 157 aa overlap. ORF ftt0831c YP_169837.1 Similar to FKBX_ECOLI (P22563) FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase from Escherichia coli (148 aa). FASTA: opt: 357 Z-score: 475.0 E(): 1.4e-18 Smith-Waterman score: 357; 38.129 identity in 139 aa overlap. YP_169838.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_169839.1 Similar to CHMU_BACSU Chorismate mutase from Bacillus subtilis (127 aa). FASTA: opt: 360 Z-score: 492.8 E(): 1.5e-19 Smith-Waterman score: 360; 48.305identity in 118 aa overlap. YP_169840.1 Similar to Q8EBE8 CDP-diacylglycerol--serine O-phosphatidyltransferase from Shewanella oneidensis (269 aa). FASTA: opt: 456 Z-score: 550.1 E(): 9.5e-23 Smith-Waterman score: 564; 37.209 identity in 258 aa overlap. ORF ftt0835 YP_169841.1 ORF ftt0836c YP_169842.1 Similar to TOLQ_ECOLI TolQ protein from Escherichia coli (230 aa). FASTA: opt: 568 Z-score: 690.3 E(): 1.5e-30 Smith-Waterman score: 568; 38.991 identity in 218 aa overlap. YP_169843.1 Similar to TOLR_ECOLI TolR protein from Escherichia coli (142 aa). FASTA: opt: 303 Z-score: 379.2 bits: 76.1 E(): 3.2e-13 Smith-Waterman score: 303; 39.259identity in 135 aa overlap. YP_169844.1 FTT0839 Contains similarity to Pfam domain PF06519 (TolA protein), Score=-66.2, E-value=1.4e-05 YP_169845.1 Similar to TOLB_ECOLI TolB protein precursor from Eschericia coli (430 aa). FASTA: opt: 692 Z-score: 785.2 E(): 7.6e-36 Smith-Waterman score: 717; 31.685identity in 445 aa overlap. TolB appears more highly conserved in other species: potential paralog YP_169846.1 ORF ftt0841 YP_169847.1 Similar to PAL_ECOLI Peptidoglycan-associated lipoprotein from Escherichia coli (173 aa). FASTA: opt: 306 Z-score: 383.2 E(): 1.9e-13 Smith-Waterman score: 306; 33.333 identity in 162 aa overlap. ORF ftt0842 YP_169848.1 Similar to Q9K315 Hypothetical protein VCA0343 OR VCA029 from Vibrio cholerae (83 aa). FASTA: opt: 250 Z-score: 356.2 E(): 6e-12 Smith-Waterman score: 250; 58.462 identity (58.4620ngapped) in 65 aa overlap. ORF ftt0845 YP_169849.1 Similar to Q9KS67 Deoxyribodipyrimidine photolyase, from Vibrio cholerae (504 aa). FASTA: opt: 1071 Z-score: 1263.0 E(): 1.8e-62 Smith-Waterman score: 1097; 37.817 identity in 513 aa overlap. ORF ftt0846 YP_169850.1 Similar to Q8U6P2 Hypothetical protein Atu4765 (507 aa). FASTA: opt: 1800 Z-score: 2192.9 415.3 E(): 3e-114 Smith-Waterman score: 1800; 53.608identity in 485 aa overlap. ORF ftt0847 YP_169851.1 Similar to Q8P3G1 Hypothetical protein XCC4110 from Xanthomonas campestris (51 aa). FASTA: opt: 243 Z-score: 366.5 E(): 1.6e-12 Smith-Waterman score: 243; 63.636 identity in 44 aa overlap ORF ftt0848 YP_169852.1 Similar to Q81YH5 Bile acid transporter family protein from Bacillus anthracis (322 aa). FASTA: initn: 551 init1: 399 opt: 605 Z-score: 641.1 E(): 8.1e-28 Smith-Waterman score: 605; 32.432identity in 296 aa overlap. ORF ftt0849 YP_169853.1 Similar to Q930D7 Hypothetical protein RA0261 Rhizobium meliloti (222 aa). FASTA: opt: 521 Z-score: 614.9 E(): 2.3e-26 Smith-Waterman score: 521; 42.424 identity in 198 aa overlap. ORF ftt0850 YP_169854.1 Similar to Q83C04 Membrane protein, from Coxiella burnetii (263 aa). FASTA: opt: 338 Z-score: 387.6 E(): 1.1e-13 Smith-Waterman score: 341; 28.625 identity in 269 aa overlap. ORF ftt0851 YP_169855.1 Similar to Q8PY17 Arsenite permease from Methanosarcina mazei (420 aa). FASTA: opt: 1294 Z-score: 1359.3 E(): 8e-68 Smith-Waterman score: 1294; 49.144 identity in 409 aa overlap. ORF ftt0853 YP_169856.1 Similar to Q8EM34 Hypothetical conserved protein from Oceanobacillus iheyensis (123 aa). FASTA: opt: 271 Z-score: 341.6 E(): 3.9e-11 Smith-Waterman score: 271; 37.190 identity in 121 aa overlap. ORF ftt0854c YP_169857.1 Weakly similar to Q9KR35 Hypothetical protein VC1812 from Vibrio cholerae (139 aa). FASTA: opt: 184 Z-score: 256.0 E(): 2.3e-06 Smith-Waterman score: 184; 29.245 identity in 106 aa overlap. ORF ftt0855c YP_169858.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_169859.1 Weakly similar to similar to Q83F94 Chorismate--pyruvate lyase, from Coxiella burnetii (185 aa). FASTA: opt: 178 Z-score: 231.0 E(): 5.6e-05 Smith-Waterman score: 178; 27.215identity in 158 aa overlap ORF ftt0857c YP_169860.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_169861.1 ORF ftt0859c YP_169862.1 ORF ftt0860c YP_169863.1 Similar to FMA2_BACNO (P17824) Fimbrial protein precursor (Pilin) from Bacteroides nodosus (Dichelobacter nodosus) (160 aa). FASTA: opt: 169 Z-score: 222.1 E(): 0.00018 Smith-Waterman score: 169; 34.646 identity in 127 aa overlap The pili fiber building block protein has a highly distinct primary structure; a short positively charged leader sequence, and a highly conserved and highly hydrophobic amino-terminal domain which forms the core of the pilus fiber; A variety of studies suggest that the invariant glycine (G) at -1 is required for prepilin cleavage and assembly and that the glutamate (E) at + 5 is essential for assembly and efficient N-terminal methylation but not cleavage. The region near the carboxy terminus is often hydrophilic and is stabilized by one or two disulfide bridges that may be involved in recognition of receptors. The genes with these characteristics are usually termed pilA, pilE, pilV, pilW, pilX and FimU. (Mattick John S.. 'Type IV Pili and twitching motility'. Annu. Rev. Microbiol. 2002. 56:289-314.) This protein has all the characteristics described above, but shows a weak global homology. ORF ftt0861c YP_169864.1 metalloprotease YP_169865.1 Similar to Q83DZ3 LemA protein from Coxiella burnetii (192 aa) initn: 723 init1: 655 opt: 732 Z-score: 803.2 bits: 155.4 E(): 7.6e-37 Smith-Waterman score: 732; 60.417 identity in 192 aa overlap. ORF ftt0863c YP_169866.1 Similar to Q87XZ5 Transcriptional regulator, LysR family, from Pseudomonas syringae (308 aa). FASTA: opt: 591 Z-score: 726.5 E(): 1.4e-32 Smith-Waterman score: 591; 34.948 identity in 289 aa overlap. ORF ftt0864c YP_169867.1 ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 transposase from Francisella tularensis (247 aa). YP_169868.1 Similar to Q9RA93 ArsR from Sinorhizobium sp. As4 (115 aa). FASTA: opt: 185 Z-score: 259.0 bits: 53.3 E(): 1.6e-06 Smith-Waterman score: 185; 27.184 identity in 103 aa overlap. ORF ftt0868c YP_169869.1 ORF ftt0869 YP_169870.1 ORF ftt0870c YP_169871.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_169872.1 ORF ftt0872c YP_169873.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_169874.1 ORF ftt0874c YP_169875.1 Similar to YOHD_ECOLI (P33366) Hypothetical protein yohD from Escherichia coli (192 aa). FASTA: opt: 311 Z-score: 379.7 bits: 77.1 E(): 2.9e-13 Smith-Waterman score: 311; 24.870 identity (25.806 ungapped) in 193 aa overlap. ORF ftt0875c YP_169876.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_169877.1 ORF ftt0877c YP_169878.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_169879.1 superoxide dismutase (Cu-Zn) precusor. Identical to SODC_FRATU from F. tularensis LVS. YP_169880.1 Similar to AAP09927 Arginine permease from Bacillus cereus (474 aa). FASTA: opt: 1041 Z-score: 1224.1 E(): 2.5e-60 Smith-Waterman score: 1041; 35.604 identity in 455 aa overlap. ORF ftt0881c YP_169881.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_169882.1 Similar to Q8D6R6 Predicted Co/Zn/Cd cation transporter from Vibrio vulnificus (297 aa). FASTA: opt: 344 Z-score: 414.1 E(): 3.3e-15 Smith-Waterman score: 344; 25.296 identity in 253 aa overlap. ORF ftt0885 YP_169883.1 Similar to P52118 DNA repair protein recN (Recombination protein (554 aa) fasta scores; opt: 1371 Z-score: 1221.7 E(): 3.4e-60 Smith-Waterman score: 1371; 39.674 identity in 552 aa overlap. ORF ftt0886 YP_169884.1 ORF ftt0887c YP_169885.1 Similar to Q59607 Pilin precursor from Neisseria gonorrhoeae (169 aa). FASTA: opt: 244 Z-score: 305.7 E(): 3.5e-09 Smith-Waterman score: 244; 30.435 identity in 138 aa overlap. The pili fiber building block protein has a highly distinct primary structure; a short positively charged leader sequence, and a highly conserved and highly hydrophobic amino-terminal domain which forms the core of the pilus fiber; A variety of studies suggest that the invariant glycine (G) at -1 is required for prepilin cleavage and assembly and that the glutamate (E) at + 5 is essential for assembly and efficient N-terminal methylation but not cleavage. The region near the carboxy terminus is often hydrophilic and is stabilized by one or two disulfide bridges that may be involved in recognition of receptors. The genes with these characteristics are usually termed pilA, pilE, pilV, pilW, pilX and FimU. (Mattick John S.. 'Type IV Pili and twitching motility'. Annu. Rev. Microbiol. 2002. 56:289-314.) This protein has all the characteristics described above. ORF ftt0888c YP_169886.1 Similar to Q820M2 Fimbrial protein pilin:bacterial general secretion pathway protein H from Nitrosomonas europaea (136 aa). FASTA: opt: 216 Z-score: 280.1 E(): 1e-07 Smith-Waterman score: 218; 32.639 identity in 144 aa overlap. The pili fiber building block protein has a highly distinct primary structure; a short positively charged leader sequence, and a highly conserved and highly hydrophobic amino-terminal domain which forms the core of the pilus fiber; A variety of studies suggest that the invariant glycine (G) at -1 is required for prepilin cleavage and assembly and that the glutamate (E) at + 5 is essential for assembly and efficient N-terminal methylation but not cleavage. The region near the carboxy terminus is often hydrophilic and is stabilized by one or two disulfide bridges that may be involved in recognition of receptors. The genes with these characteristics are usually termed pilA, pilE, pilV, pilW, pilX and FimU. (Mattick John S.. 'Type IV Pili and twitching motility'. Annu. Rev. Microbiol. 2002. 56:289-314.) This protein has all the characteristics described above. ORF ftt0889c YP_169887.1 Similar to Q8Y1X9 Type 4 fimbrial pilin signal peptide protein from Ralstonia solanacearum (168 aa). FASTA: opt: 278 Z-score: 327.6 E(): 2.1e-10 Smith-Waterman score: 292; 38.095identity in 147 aa overlap. The pili fiber building block protein has a highly distinct primary structure; a short positively charged leader sequence, and a highly conserved and highly hydrophobic amino-terminal domain which forms the core of the pilus fiber; A variety of studies suggest that the invariant glycine (G) at -1 is required for prepilin cleavage and assembly and that the glutamate (E) at + 5 is essential for assembly and efficient N-terminal methylation but not cleavage. The region near the carboxy terminus is often hydrophilic and is stabilized by one or two disulfide bridges that may be involved in recognition of receptors. The genes with these characteristics are usually termed pilA, pilE, pilV, pilW, pilX and FimU. (Mattick John S.. 'Type IV Pili and twitching motility'. Annu. Rev. Microbiol. 2002. 56:289-314.) This protein has all the characteristics described above. ORF ftt0890c YP_169888.1 Similar to Q98NS1 Hypothetical protein mlr0012 from Rhizobium loti (244 aa). FASTA: opt: 327 Z-score: 404.4 bits: 82.2 E(): 1.2e-14 Smith-Waterman score: 327; 32.308 identity in 195 aa overlap. ORF ftt0891 YP_169889.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_169890.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_169891.1 Amino acids 1-327 (PurC) similar to AAR06292 SAICAR synthetase from Nicotiana tabacum (399 aa). BLAST: Expect = e-105 Identities = 187/322 (58), Positives = 236/322 (73), Gaps = 6/322 (1). Amino acids 328-770 (PurD) similar to ZP_00077753 Phosphoribosylamine-glycine ligase from Methanosarcina barkeri (433). BLAST: Expect = e-108 Identities = 204/436 (46), Positives = 285/436 (65), Gaps = 3/436 (0) YP_169892.1 Similar to Q8DBC3 Folate-dependent phosphoribosylglycinamide formyltransferase from Vibrio vulnificus (212 aa). FASTA: opt: 530 Z-score: 633.0 E(): 2.1e-27 Smith-Waterman score: 530; 45.263 identity in 190 aa overlap. YP_169893.1 Similar to P72157 Phosphoribosylaminoimidazole carboxylase catalytic subunit from Psudomonas aeruginosa (163 aa). FASTA: opt: 719 Z-score: 894.1 E(): 6.6e-42 Smith-Waterman score: 719; 70.988 identity n 162 aa overlap YP_169894.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_169895.1 Similar to Q88N88 Conserved hypothetical protein TIGR002 from Pseudomonas putida (124 aa). FASTA: opt: 291 Z-score: 402.6 E(): 1.6e-14 Smith-Waterman score: 291; 38.938 identity in 113 aa overlap. ORF ftt0898c YP_169896.1 Similar to P27298 Oligopeptidase A from Escherichia coli (680 aa). FASTA: opt: 1936 Z-score: 2040.0 E(): 8.9e-106 Smith-Waterman score: 1936; 43.722 identity in 677 aa overlap. YP_169897.1 ORF ftt0900 YP_169898.1 Paralog to conserved hypothetical lipoprotein lpnB. YP_169899.1 paralog of FTT0903 ORF ftt0902 YP_169900.1 paralog of FTT0902 ORF ftt0903 YP_169901.1 Similar to P18149 17 kDa major membrane protein precursor from Francisella tularensis ssp. holarctica strain LVS (149 aa). FASTA: opt: 274 Z-score: 359.1 E(): 4.1e-12 Smith-Waterman score: 274; 32.468 identity (33.5570ngapped) in 154 aa overlap. Paralog to conserved hypothetical lipoprotein lpnA. YP_169902.1 Similar to Q8KQ19 PilO from Pseudomonas aeruginosa (461 aa). FASTA: opt: 283 Z-score: 329.7 E(): 1.6e-10 Smith-Waterman score: 283; 25.284 identity in 352 aa overlap. PilO is required for glycosylation of Pseudomonas aeruginosa pilin. ORF ftt0905 YP_169903.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity YP_169904.1 Similar to Q9F260 Partition protein from Actinobacillus actinomycetemcomitans (213 aa). FASTA: opt: 286 Z-score: 339.2 E(): 4.8e-11 mith-Waterman score: 286; 29.245 identity in 212 aa overlap YP_169905.1 Similar to Q9CJA4 Chromosome partitioning protein from Lactococcus lactis (261 aa). FASTA: opt: 399 Z-score: 442.0 E(): 9e-17 Smith-Waterman score: 399; 33.333 identity in 264 aa overlap YP_169906.1 Similar to Q88LT5 Glutamine amidotransferase, class I from Pseudomonas putida (244 aa). FASTA: opt: 589 Z-score: 771.5 bits: 150.1 E(): 4.4e-35 Smith-Waterman score: 589; 36.325identity in 234 aa overlap. ORF ftt0909 YP_169907.1 Weakly similar to Q8GNM7 Lysophospholipase A from Legionella pneumophila (309 aa). FASTA: 86 opt: 302 Z-score: 378.8 bits: 78.1 E(): 3.3e-13 Smith-Waterman score: 360; 29.795 identity in 292 aa overlap. ORF ftt0910 YP_169908.1 Similar with Q87NK1 Hypothetical protein from Vibrio parahaemolyticus (195 aa) fasta scores; opt: 523 Z-score: 649.0 E(): 2.7e-28 Smith-Waterman score: 523; 42.857 identity in 189 aa overlap ORF ftt0911 YP_169909.1 Similar to Q8EHM3 Ribosomal RNA large subunit methyltransferase J from Shewanella oneidensis (209 aa). FASTA: opt: 730 Z-score: 844.0 E(): 3.7e-39 Smith-Waterman score: 730; 53.202identity in 203 aa overlap YP_169910.1 ORF ftt0913 YP_169911.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_169912.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_169913.1 Similar to Q9CKF8 RibF from Pasteurella multocida (311 aa). FASTA: opt: 845 Z-score: 994.4 E(): 1.5e-47 Smith-Waterman score: 845; 44.481 identity in 308 aa overlap YP_169914.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_169915.1 ORF ftt0918 YP_169916.1 ORF ftt0919 YP_169917.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_169918.1 Similarity to Q98JM3 Probable fatty acid hydroxylase from Rhizobium loti (164 aa). FASTA: opt: 305 Z-score: 383.8 E(): 1.6e-13 Smith-Waterman score: 305; 31.902 identity in 163 aa overlap. ORF ftt0922 YP_169919.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_169920.1 ORF ftt0924 YP_169921.1 Similarity to P44787 Methionyl-tRNA formyltransferase from Haemophilus ducreyi (318 aa). FASTA: opt: 949 Z-score: 1086.2 E(): 1.2e-52 Smith-Waterman score: 958; 48.387 identity in 310 aa overlap YP_169922.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_169923.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_169924.1 SImilar to Q8RD12 Beta-glucosidase-related glycosidases from Thermoanaerobacter tengcongensis (591 aa). FASTA: opt: 1047 Z-score: 1141.5 E(): 9.9e-56 Smith-Waterman score: 1062; 35.106 identity in 564 aa overlap. ORF ftt0928c YP_169925.1 Similar to Q89YS8 Glucose/galactose transporter from Bacteroides thetaiotaomicron (415 aa). FASTA: opt: 1125 Z-score: 1176.3 bits: 226.6 E(): 1.3e-57 Smith-Waterman score: 1125; 41.446 identity in 415 aa overlap ORF ftt0931 YP_169926.1 Similar to Q8A1Q9 ROK family transcriptional repressor from Bacteroides thetaiotaomicron (298 aa). FASTA: opt: 482 Z-score: 605.6 E(): 7.7e-26 Smith-Waterman score: 482; 30.769 identity in 286 aa overlap ORF ftt0932 YP_169927.1 Similar to AAO90524 Dethiobiotin synthetase from Coxiella burnetii (242 aa). FASTA: opt: 464 Z-score: 551.2 E(): 7.5e-23 Smith-Waterman score: 464; 34.498 identity in 229 aa overlap YP_169928.1 Similar to AAO90525 Biotin synthesis protein BioC, from Coxiella burnetii (248 aa) FASTA: opt: 232 Z-score: 273.5 E(): 2.2e-07 Smith-Waterman score: 232; 23.293 identity in 249 aa overlap YP_169929.1 Similar to AAO90527 8-amino-7-oxononanoate synthase (384 aa) fasta scores; opt: 763 Z-score: 912.3 E(): 5.8e-43 Smith-Waterman score: 763; 39.053identity in 338 aa overlap YP_169930.1 Similar to AAO90528 Biotin synthase from Coxiella burnetii (321 aa) FASTA: opt: 1220 Z-score: 1430.1 E(): 8.3e-72 Smith-Waterman score: 1220; 60.396 identity in 303 aa overlap YP_169931.1 Similar to AAO90529 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase from Coxiella burnetii (442 aa). FASTA: opt: 1486 Z-score: 1733.9 E(): 9.9e-89 Smith-Waterman score: 1486; 50.588 identity in 425 aa overlap YP_169932.1 catalyzes the formation of inosine from adenosine YP_169933.1 Similar to Q88CI3 Conserved hypothetical protein from Pseudomonas putida (160 aa). FASTA: opt: 297 Z-score: 384.8 E(): 1.4e-13 Smith-Waterman score: 297; 32.653 identity in 147 aa overlap ORF ftt0940c YP_169934.1 Similar to Q97VW1 Lipase (lipP-1) from Sulfolobus solfataricus (305 aa). FASTA: opt: 488 Z-score: 622.4 E(): 8.9e-27 Smith-Waterman score: 488; 32.990 identity in 291 aa overlap. ORF ftt0941c YP_169935.1 Similar to Q821E2 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase from Chlamydophila caviae (447 aa). FASTA: opt: 517 Z-score: 602.2 E(): 1.2e-25 Smith-Waterman score: 604; 30.664 identity in 437 aa overlap YP_169936.1 Similar to O84620 Probable dihydroneopterin aldolase (124 aa) fasta scores; opt: 191 Z-score: 262.4 E(): 9.2e-07 Smith-Waterman score: 191; 30.189identity in 106 aa overlap YP_169937.1 Similar to Q9CHK3 O-succinylbenzoic acid-CoA ligase from Lactococcus lactis (420 aa). opt: 373 Z-score: 423.0 E(): 1e-15 Smith-Waterman score: 434; 27.692 identity in 390 aa overlap ORF ftt0944 YP_169938.1 Similar to Q8ESD8 Para-aminobenzoate synthase component II (585 aa) fasta scores; opt: 1108 Z-score: 1235.5 E(): 5.7e-61 Smith-Waterman score: 1108; 33.851 identity in 579 aa overlap. ORF ftt0945 YP_169939.1 Similarity to Q972A0 anthranilate synthase component from Sulfolobus tokodaii (193 aa). FASTA: opt: 499 Z-score: 620.3 E(): 1.1e-26 Smith-Waterman score: 499; 40.741 identity in 189 aa overlap. Closely related to pabA proteins as they possess a shared domain feature YP_169940.1 Similar to Q92QZ5 oxidoreductase protein from Rhizobium meliloti (347 aa). FASTA: opt: 1125 Z-score: 1304.5 E(): 8.2e-65 Smith-Waterman score: 1125; 50.140 identity in 357 aa overlap. pseudogene: flanked by pseudogenes ORF ftt0948c YP_169941.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_169942.1 Similar to Q8D6C6 Superfamily II DNA and RNA helicase from Vibrio vulnificus (509 aa). FASTA: opt: 1533 Z-score: 1649.9 E(): 4.8e-84 Smith-Waterman score: 1533; 56.036 identity in 439 aa overlap YP_169943.1 Similar to Q9KTB5 Proton/peptide symporter family protein from Vibrio cholerae (514 aa). FASTA: opt: 1329 Z-score: 1443.3 E(): 1.5e-72 Smith-Waterman score: 1329; 42.629identity in 502 aa overlap. ORF ftt0953c YP_169944.1 Similar to O29392 Hypothetical protein AF0869 from Archaeoglobus fulgidus (108 aa). FASTA: opt: 272 Z-score: 377.5 E(): 3.9e-13 Smith-Waterman score: 272; 42.056 identity in 107 aa overlap ORF ftt0954c YP_169945.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_169946.1 Similar to AAO50751 (Q86L42) Hypothetical protein from Dictyostelium discoideum (239 aa). FASTA: opt: 229 Z-score: 273.3 E(): 2.3e-07 Smith-Waterman score: 253; 29.437 identity in 231 aa overlap ORF ftt0956c YP_169947.1 Similar to Q83YE2 Shy8 from Streptomyces hygroscopicus (163 aa). FASTA: opt: 343 Z-score: 413.4 bits: 82.8 E(): 3.9e-15 Smith-Waterman score: 343; 36.420 identity in 162 aa overlap. ORF ftt0957c YP_169948.1 Similar to Q9HWL9 Probable short-chain dehydrogenase from Pseudomonas aeruginosa (238 aa). FASTA: opt: 848 Z-score: 1032.8 E(): 1.1e-49 Smith-Waterman score: 848; 55.932 identity in 236 aa overlap ORF ftt0958c YP_169949.1 Similar to Q83EM1 Exodeoxyribonuclease III from Coxiella burnetii (259 aa). FASTA: opt: 991 Z-score: 1173.5 E(): 1.6e-57 Smith-Waterman score: 991; 54.789 identity in 261 aa overlap YP_169950.1 Simiar to Q8EAC2 Conserved hypothetical protein Shewanella oneidensis (371 aa). FASTA: opt: 607 Z-score: 717.9 E(): 3.9e-32 Smith-Waterman score: 607; 32.622 identity in 328 aa overlap ORF ftt0960 YP_169951.1 Similar to P40717 Modulator of drug activity B from Escherichia coli (193 aa). FASTA: opt: 900 Z-score: 1129.6 E(): 4.5e-55 Smith-Waterman score: 900; 63.542 identity in 192 aa overlap. YP_169952.1 Similar to Q87Z85 ThiJ/PfpI family protein from Pseudomonas syringae (225 aa). FASTA: opt: 570 Z-score: 665.3 E(): 3.3e-29 Smith-Waterman score: 570; 38.991 identity in 218 aa overlap ORF ftt0962 YP_169953.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_169954.1 Similar to Q9CLN6 Ffh from Pasteurella multocida (458 aa). FASTA: opt: 1851 Z-score: 1789.9 E(): 7.5e-92 Smith-Waterman score: 1851; 61.790 identity in 458 aa overlap YP_169955.1 Similar to Q928M9 Hypothetical protein lin2503 from Listeria innocua (279 aa). FASTA: opt: 733 Z-score: 821.7 E(): 6.4e-38 Smith-Waterman score: 733; 41.852 identity in 270 aa overlap. ORF ftt0965c YP_169956.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_169957.1 Similar to Q83BZ0 Amino acid antiporter from Coxiella burnetii (474 aa). FASTA: 432 opt: 1275 Z-score: 1361.2 E(): 6.3e-68 Smith-Waterman score: 1275; 40.171 identity in 468 aa overlap. ORF ftt0968c YP_169958.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_169959.1 Similar to Q8PIG4 Hypothetical protein XAC2934 from Xanthomonas axonopodis (152 aa). FASTA: opt: 281 Z-score: 360.3 E(): 3.2e-12 Smith-Waterman score: 281; 33.588 identity in 131 aa overlap ORF ftt0970 YP_169960.1 with SufCD activates cysteine desulfurase SufS YP_169961.1 Similar to Q8PIG2 ABC transporter ATP-binding protein from Xanthomonas axonopodis (254 aa). FASTA: opt: 1080 Z-score: 1117.5 E(): 2.1e-54 Smith-Waterman score: 1080; 65.041 identity in 246 aa overlap. ORF ftt0972 YP_169962.1 Similar to Q83BX9 Hypothetical protein CBU1358 Coxiella burnetii (426 aa). FASTA: opt: 433 Z-score: 493.2 E(): 1.3e-19 Smith-Waterman score: 460; 29.282 identity in 362 aa overlap ORF ftt0973 YP_169963.1 Weakly similar to Q83CZ8 Hypothetical protein Coxiella burnetii (227 aa) 76 opt: 235 Z-score: 276.0 bits: 58.3 E(): 1.8e-07 Smith-Waterman score: 235; 25.000 identity in 236 aa overlap. ORF ftt0975 YP_169964.1 Similar to P37395 Thioredoxin from Cyanidium caldarium (107 aa) fasta scores; opt: 333 Z-score: 452.0 E(): 2.5e-17 Smith-Waterman score: 333; 45.098identity in 102 aa overlap YP_169965.1 Similar to Q89DD5 Bsl7504 protein from Bradyrhizobium japonicum (99 aa). FASTA: opt: 209 Z-score: 292.0 E(): 2e-08 Smith-Waterman score: 209; 38.462 identity in 91 aa overlap ORF ftt0977c YP_169966.1 ORF ftt0978c YP_169967.1 amino-acid permease, similarity to P39137 Amino-acid permease rocE from Bacillus subtilis (467 aa). FASTA: opt: 1272 Z-score: 1431.9 E(): 6.6e-72 Smith-Waterman score: 1272; 40.919 identity in 457 aa overlap. ORF ftt0979c YP_169968.1 Similar to Q8UKI4 Aminotransferase, class II from Agrobacterium tumefaciens (413 aa). FASTA: opt: 486 Z-score: 559.2 E(): 2.7e-23 Smith-Waterman score: 554; 28.493 identity in 365 aa overlap ORF ftt0980 YP_169969.1 Weak homology to two-component sensory protein. ORF ftt0981 YP_169970.1 ORF ftt0982 YP_169972.1 Similar to Q87SF6 Mutator MutT protein from Vibrio parahaemolyticus (132 aa). FASTA: opt: 268 Z-score: 340.9 E(): 3.9e-11 Smith-Waterman score: 268; 29.545identity in 132 aa overlap. YP_169973.1 Similar to Q8EBZ9 Conserved hypothetical protein from Shewanella oneidensis (187 aa). FASTA: opt: 386 Z-score: 477.0 E(): 1e-18 Smith-Waterman score: 386; 36.022 identity in 186 aa overlap ORF ftt0985 YP_169974.1 Similar to Q9L3I7 Holliday junction resolvase from Aeromonas hydrophila (140 aa). FASTA: opt: 336 Z-score: 430.0 E(): 4.7e-16 Smith-Waterman score: 336; 36.567 identity in 134 aa overlap Holliday junction resolvase predicted in other proteins ORF ftt0986 YP_169975.1 ORF ftt0987 YP_169976.1 ORF ftt0988 YP_169977.1 Similar to Q9I271 Hypothetical protein PA2044 from Pseudomonas aeruginosa (624 aa). FASTA: opt: 447 Z-score: 484.0 E(): 4.2e-19 Smith-Waterman score: 447; 22.203 identity in 572 aa overlap. ORF ftt0989 YP_169978.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_169979.1 ORF ftt0991 YP_169980.1 Similar to Q8A7A2 membrane protein from Bacteroides thetaiotaomicron (391 aa). FASTA: opt: 908 Z-score: 1062.3 E(): 2.6e-51 Smith-Waterman score: 908; 37.637 identity in 364 aa overlap. ORF ftt0992 YP_169981.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_169982.1 Similar to Q8XWU1 Probable MRP protein ATP-binding from Ralstonia solanacearum. (362 aa). FASTA: opt: 1008 Z-score: 1105.3 E(): 1e-53 Smith-Waterman score: 1008; 52.688 identity in 279 aa overlap. ORF ftt0994c YP_169983.1 Similarity to Q8UDH1 MFS permease[proline/betaine] from Agrobacterium tumefaciens (443 aa). FASTA: opt: 727 Z-score: 824.0 E(): 4.8e-38 Smith-Waterman score: 828; 35.507identity in 414 aa overlap ORF ftt0995 YP_169984.1 Similar to P71040 Probable cardiolipin synthetase 2 from Bacillus subtilis (482 aa). FASTA: opt: 835 Z-score: 944.7 E(): 9.1e-45 Smith-Waterman score: 835; 32.525 identity in 495 aa overlap YP_169985.1 ORF ftt0998 YP_169986.1 Similar to Q8FUU8 Cobalamin synthesis protein/P47K family protein from Brucella suis (400 aa). FASTA: opt: 1643 Z-score: 1956.7 E(): 4.3e-101 Smith-Waterman score: 1643; 58.396 identity in 399 aa overlap. YP_169987.1 Similar to Q8ZJ15 regulatory protein from Yersinia pestis (169 aa). FASTA: opt: 313 Z-score: 406.8 E(): 9.2e-15 Smith-Waterman score: 313; 36.429 identity in 140 aa overlap. ORF ftt1001 YP_169988.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_169989.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_169990.1 Similar to Q9RX03 Hypothetical protein DR0512 from Deinococcus radiodurans (301 aa). Similar to opt: 577 Z-score: 644.6 E(): 5.1e-28 Smith-Waterman score: 577; 33.094 identity in 278 aa overlap. ORF ftt1004c YP_169991.1 Similar to Q8X5Q8 transport protein from Escherichia coli (489 aa). FASTA: opt: 1050 Z-score: 1137.7 E(): 1.8e-55 Smith-Waterman score: 1050; 35.569 identity in 492 aa overlap. YP_169992.1 ORF ftt1006 YP_169995.1 ORF ftt1009 YP_169996.1 Similar to Q81BZ8 Transcriptional regulator,Cro/CI family protein from Bacillus cereus (strain ATCC 14579 / DSM 31) (71 aa). FASTA: opt: 263 Z-score: 391.6 E(): 6.4e-14 Smith-Waterman score: 263; 60.606 identity in 66 aa overlap. ORF ftt1010 YP_169997.1 ORF ftt1011 YP_169998.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_169999.1 Similar to YWFD_BACSU (P39640) Hypothetical oxidoreductase ywfD from Bacillus subtilis (255 aa). FASTA: opt: 410 Z-score: 474.7 E(): 1.5e-18 Smith-Waterman score: 471; 38.710 identity in 248 aa overlap. ORF ftt1014c YP_170000.1 ORF ftt1015 YP_170001.1 Similar to Q9JQY7 lipase (GDSL lipase family protein) from Neisseria meningitidis (213 aa). FASTA: opt: 358 Z-score: 439.3 E(): 1.4e-16 Smith-Waterman score: 358; 32.203 identity in 177 aa overlap. ORF ftt1016c YP_170002.1 ORF ftt1017c YP_170003.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_170004.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_170005.1 Similar to Q83EA0 Amino acid permease family protein from Coxiella burnetii (531 aa). FASTA: opt: 925 Z-score: 996.3 E(): 1.3e-47 Smith-Waterman score: 947; 29.379 identity in 531 aa overlap. ORF ftt1020c YP_170006.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_170007.1 Similar to Y125_PYRHO (O57865) Hypothetical protein PH0125 from Pyrococcus horikoshii (257 aa) (from 1-260). FASTA: opt: 520 Z-score: 632.1 E(): 2.6e-27 Smith-Waterman score: 520; 35.600 identity in 250 aa overlap AND Q97VT8 Lipase (lipP-2) from Sulfolobus solfataricus (311 aa) (from 300-610). FASTA: opt: 613 Z-score: 743.7 E(): 1.6e-33 Smith-Waterman score: 613; 34.586 identity in 266 aa overlap Possible merged protein due to a missing stop codon between 2 CDSs? ORF ftt1022c YP_170008.1 Similar to Q8EGL6 Fumarylacetoacetate hydrolase family protein from Shewanella oneidensis (208 aa). FASTA: opt: 599 Z-score: 746.5 E(): 1.1e-33 Smith-Waterman score: 599; 51.913 identity in 183 aa overlap. ORF ftt1023c YP_170009.1 Similar to Q8ZB44 Probable ABC transporter ATP-binding protein from Yersinia pestis (241 aa). FASTA: opt: 1091 Z-score: 1233.5 E(): 8.2e-61 Smith-Waterman score: 1091; 65.690 identity in 239 aa overlap. YP_170010.1 ORF ftt1025c YP_170011.1 ORF ftt1026c YP_170012.1 Similar to AAP18518 Hypothetical protein yrbI from Escherichia coli (188 aa). FASTA: initn: 454 init1: 247 opt: 453 Z-score: 558.6 bits: 110.0 E(): 3.2e-23 Smith-Waterman score: 453; 50.000 identity in 152 aa overlap. YP_170013.1 Similar to IPYR_YERPE (Q8ZB98) Inorganic pyrophosphatase from Yersinia pestis (175 aa). FASTA: opt: 762 Z-score: 1001.4 E(): 6.9e-48 Smith-Waterman score: 762; 62.209 identity in 172 aa overlap. YP_170014.1 Similar to Q87VW4 D-alanyl-D-alanine carboxypeptidase from Pseudomonas syringae (pv. tomato) (386 aa). FASTA: opt: 602 Z-score: 704.0 E(): 2.5e-31 Smith-Waterman score: 794; 36.409 identity in 401 aa overlap. YP_170015.1 Similar to YE87_NITEU (Q82UJ7) Hypothetical UPF0250 protein NE1487 from Nitrosomonas europaea (87 aa). FASTA: opt: 235 Z-score: 328.5 E(): 2.1e-10 Smith-Waterman score: 235; 36.471 identity in 85 aa overlap. ORF ftt1030 YP_170016.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_170017.1 Similar to Q8UDU6 NADH dehydrogenase from Agrobacterium tumefaciens (strain C58 / ATCC 33970) (438 aa). FASTA: opt: 826 Z-score: 983.7 E(): 6.7e-47 Smith-Waterman score: 826; 32.854 identity in 417 aa overlap. YP_170018.1 Similar to P77890 LprpoD (RNA polymerase sigma factor) from Legionella pneumophila (620 aa). FASTA: opt: 1367 Z-score: 1480.9 E(): 1.4e-74 Smith-Waterman score: 1624; 47.182 identity in 621 aa overlap. YP_170019.1 Similar to Q8DEG2 DNA primase from Vibrio vulnificus (587 aa). FASTA: opt: 1152 Z-score: 1324.3 E(): 7.2e-66 Smith-Waterman score: 1155; 39.679 identity in 499 aa overlap. YP_170020.1 Similar to Q87SL6 Conserved hypothetical protein from Vibrio parahaemolyticus (147 aa). FASTA: opt: 473 Z-score: 548.0 E(): 1.2e-22 Smith-Waterman score: 473; 47.586 identity in 145 aa overlap. ORF ftt1037c YP_170021.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_170022.1 Similar to Q83FD1 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase from Coxiella burnetii (477 aa). FASTA: opt: 654 Z-score: 780.3 E(): 1.4e-35 Smith-Waterman score: 654; 29.436 identity in 479 aa overlap. YP_170023.1 Similar to Q8EBG1 Conserved hypothetical protein from Shewanella oneidensis (205 aa). FASTA: opt: 610 Z-score: 776.5 E(): 2.3e-35 Smith-Waterman score: 610; 45.810 identity in 179 aa overlap. ORF ftt1040 YP_170024.1 Similar to Q8ESG1 Hypothetical conserved protein from Oceanobacillus iheyensis (134 aa). FASTA: opt: 215 Z-score: 303.3 E(): 5.3e-09 Smith-Waterman score: 215; 32.773 identity in 119 aa overlap. ORF ftt1041 YP_170025.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_170026.1 Similar to O32766 Macrophage infectivity potentiator from Legionella hackeliae (249 aa). FASTA: opt: 235 Z-score: 273.3 E(): 2.5e-07 Smith-Waterman score: 343; 27.599 identity in 279 aa overlap. ORF ftt1043 YP_170027.1 Similar to Q8EB79 Octaprenyl-diphosphate synthase from Shewanella oneidensis (323 aa). FASTA: opt: 1117 Z-score: 1360.2 E(): 7.1e-68 Smith-Waterman score: 1117; 53.704 identity in 324 aa overlap. YP_170028.1 ORF ftt1045c YP_170029.1 ORF ftt1046c YP_170030.2 ORF ftt1047c YP_170031.2 ORF ftt1048c YP_170032.1 Similar to CYSN_VIBPA (Q87SX9) Sulfate adenylyltransferase subunit 1 from Vibrio parahaemolyticus (476 aa). FASTA: opt: 1823 Z-score: 2170.8 E(): 5e-113 Smith-Waterman score: 1823; 59.488 identity in 469 aa overlap. YP_170033.1 ORF ftt1051c YP_170034.1 ORF ftt1052c YP_170035.1 Similar to RIMI_ECOLI (P09453) Ribosomal-protein-alanine acetyltransferase (148 aa). FASTA: opt: 237 Z-score: 305.5 E(): 4e-09 Smith-Waterman score: 237; 36.585 identity in 123 aa overlap. YP_170036.1 ORF ftt1055c YP_170037.1 Similar to Q8ZEG0 Ribosomal large subunit pseudouridine synthase B from Yersinia pestis (318 aa). FASTA: opt: 938 Z-score: 1164.9 E(): 5.4e-57 Smith-Waterman score: 938; 56.705identity in 261 aa overlap. YP_170038.1 Similar to Q9KRM4 Fimbrial biogenesis and twitching motility protein, from Vibrio cholerae (237 aa). FASTA: opt: 249 Z-score: 293.4 E(): 1.9e-08 Smith-Waterman score: 249; 25.346 identity in 217 aa overlap. Tetratrico peptide repeat (TPR) containing protein. Shows a weak similarity to the lipoprotein pilF (Pseudomonas) that has an N-terminal type II (lipoprotein) signal sequence, followed by six tandem degenerated 34-amino acid repeats, which are involved in protein-protein interactions. ORF ftt1057c YP_170039.1 Similar to Y2A6_PSEAE (Q51385) Hypothetical protein PA3806 from Pseudomonas aeruginosa (379 aa). FASTA: opt: 1458 Z-score: 1752.5 E(): 1e-89 Smith-Waterman score: 1458; 60.434 identity in 369 aa overlap. ORF ftt1058c YP_170040.1 Similar to DNAB_PASMU (Q9CNL6) Replicative DNA helicase from Pasteurella multocida (467 aa). FASTA: opt: 1484 Z-score: 1719.2 E(): 7.2e-88 Smith-Waterman score: 1484; 51.016 identity in 443 aa overlap. YP_170041.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_170042.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_170043.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_170044.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_170046.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170047.1 ORF ftt1066c YP_170048.1 ORF ftt1068c YP_170049.1 ORF ftt1069c YP_170050.1 Similar to Q82XK5 antirestriction protein from Nitrosomonas europaea (171 aa). FASTA: opt: 426 Z-score: 519.1 E(): 5e-21 Smith-Waterman score: 426; 42.771 identity in 166 aa overlap. ORF ftt1071c YP_170051.1 ORF ftt1072 YP_170053.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170054.1 Similar to Y4MF_RHISN (P55565) Hypothetical transcriptional regulator y4mF from Rhizobium sp. (strain NGR234) (76 aa). FASTA: opt: 205 Z-score: 292.4 E(): 2.1e-08 Smith-Waterman score: 205; 47.059identity in 68 aa overlap. ORF ftt1075 YP_170055.1 Similar to Q82V03 Possible HipA protein from Nitrosomonas europaea (429 aa). FASTA: opt: 1021 Z-score: 1249.8 E(): 1e-61 Smith-Waterman score: 1021; 41.162 identity in 413 aa overlap. YP_170058.1 ORF ftt1079c YP_170059.1 ORF ftt1080c YP_170060.1 ORF ftt1081c YP_170061.1 ORF ftt1082 YP_170062.1 ORF ftt1083c YP_170063.1 Required for efficient pilin antigenic variation YP_170064.1 Similar to YM90_SHEON (Q8EES8) Hypothetical UPF0176 protein SO229 from Shewanella oneidensis (333 aa). FASTA: initn: 1561 init1: 1472 opt: 1479 Z-score: 1729.8 E(): 1.9e-88 Smith-Waterman score: 1479; 63.636identity in 330 aa overlap. ORF ftt1085 YP_170065.1 Similar to Q8EFU7 Conserved hypothetical protein from Shewanella oneidensis (279 aa). FASTA: 351 opt: 789 Z-score: 963.7 E(): 8.8e-46 Smith-Waterman score: 789; 45.290 identity in 276 aa overlap. ORF ftt1086c YP_170066.1 Similar to REP_HAEIN (P44804) ATP-dependent DNA helicase rep from Haemophilus influenzae (670 aa). FASTA: opt: 2055 Z-score: 2350.5 E(): 5e-123 Smith-Waterman score: 2055; 47.806 identity in 661 aa overlap. YP_170067.1 ORF ftt1088c YP_170068.1 Similar to Q8EW31 Hypothetical protein from Mycoplasma penetrans (194 aa). FASTA: opt: 235 Z-score: 294.7 E(): 1.6e-08 Smith-Waterman score: 235; 31.515 identity in 165 aa overlap. ORF ftt1089 YP_170069.1 Similar to Q8A546 membrane transporter involved in nicotinamide mononucleotide transport from Bacteroides thetaiotaomicron (188 aa). FASTA: opt: 285 Z-score: 336.8 E(): 7.2e-11 Smith-Waterman score: 302; 29.592 identity in 196 aa overlap. ORF ftt1090 YP_170070.1 Similar to Q9AD62 hydrolase (193 aa). FASTA: opt: 251 Z-score: 311.7 E(): 1.8e-09 Smith-Waterman score: 251; 32.075identity in 159 aa overlap. ORF ftt1091 YP_170072.1 Similar to Q8EBH2 Transaldolase from Shewanella oneidensis (318 aa). FASTA: opt: 1030 Z-score: 1249.3 E(): 1.1e-61 Smith-Waterman score: 1030; 50.938 identity in 320 aa overlap. YP_170073.1 Similar to Q83DX0 Cytosol aminopeptidase family protein from Coxiella burnetii (458 aa). FASTA: opt: 1273 Z-score: 1536.1 E(): 1.1e-77 Smith-Waterman score: 1273; 41.830 identity in 459 aa overlap. ORF ftt1094c YP_170074.1 Similar to Q88DA4 Outer membrane efflux protein from Pseudomonas putida (strain KT2440) (477 aa). FASTA: opt: 405 Z-score: 484.1 E(): 4.5e-19 Smith-Waterman score: 405; 22.907 identity in 454 aa overlap. Not a membrane protein. ORF ftt1095c YP_170075.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_170076.1 ORF ftt1097 YP_170077.1 ORF ftt1099c YP_170078.1 Similar to Q83DY7 Iojap-related protein from Coxiella burnetii (116 aa). FASTA: opt: 326 Z-score: 425.2 E(): 8.6e-16 Smith-Waterman score: 326; 41.509 identity in 106 aa overlap. ORF ftt1100 YP_170079.1 Similar to Q8Z9P6 exported protein from Salmonella typhi (281 aa). FASTA: opt: 392 Z-score: 435.6 E(): 2.3e-16 Smith-Waterman score: 392; 33.491 identity in 212 aa overlap. ORF ftt1103 YP_170080.1 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae YP_170081.1 Similar to Q8TID9 Benzodiazepine receptor TspO from Methanosarcina acetivorans (160 aa). FASTA: opt: 417 Z-score: 464.9 E(): 5.3e-18 Smith-Waterman score: 417; 40.994 identity in 161 aa overlap. YP_170082.1 Similar to Q891T6 23S rRNA methyltransferase (EC 2.1.1.-) from Clostridium tetani (260 aa). FASTA: opt: 442 Z-score: 545.7 E(): 1.7e-22 Smith-Waterman score: 442; 34.091 identity in 264 aa overlap. ORF ftt1108 YP_170083.1 Similar to Q8U768 Choloylglycine hydrolase family protein from Agrobacterium tumefaciens (strain C58 / ATCC 33970) (355 aa). FASTA: opt: 362 Z-score: 436.7 E(): 2e-16 Smith-Waterman score: 424; 28.956 identity in 297 aa overlap. ORF ftt1109 YP_170084.1 ORF ftt1110 YP_170085.1 ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 transposase from Francisella tularensis (247 aa). YP_170086.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_170087.1 ORF ftt1113c YP_170088.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_170089.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_170090.1 Similar to Q8XFR4 (Q8XFR4) membrane protein (Preprotein translocase IISP family, membrane subunit) from Salmonella typhi (110 aa). FASTA: opt: 347 Z-score: 458.8 E(): 1.2e-17 Smith-Waterman score: 347; 47.664 identity in 107 aa overlap. YP_170091.1 Similar to Q9HZE2 Hypothetical protein PA3066 from Pseudomonas aeruginosa (190 aa). FASTA: opt: 359 Z-score: 477.3 E(): 1.1e-18 Smith-Waterman score: 359; 35.638 identity in 188 aa overlap. ORF ftt1117c YP_170092.1 Similar to Q9KKY7 Hypothetical protein VCA0963 from Vibrio cholerae (307 aa). FASTA: opt: 340 Z-score: 385.2 E(): 1.5e-13 Smith-Waterman score: 340; 22.603 identity in 292 aa overlap. ORF ftt1118c YP_170093.1 Similar to Q8D460 Transcriptional regulator from Vibrio vulnificus (296 aa). FASTA: opt: 459 Z-score: 575.9 E(): 3.5e-24 Smith-Waterman score: 459; 29.197 identity in 274 aa overlap. ORF ftt1119 YP_170094.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_170095.1 ORF ftt1122c YP_170096.1 Similar to Y647_YERPE (Q8ZI67) Hypothetical UPF0078 protein YPO0647/Y3532 (216 aa). FASTA: opt: 604 Z-score: 713.6 E(): 7.4e-32 Smith-Waterman score: 604; 48.500 identity in 200 aa overlap. YP_170097.1 Similar to AAP15732 ATP-binding component of a transporter from Shigella flexneri (343 aa). FASTA: opt: 1070 Z-score: 1232.1 E(): 9.7e-61 Smith-Waterman score: 1070; 46.221 identity in 344 aa overlap. YP_170098.1 Similar to METQ_SALTI (Q8Z992) D-methionine-binding lipoprotein metQ [Precursor] from Salmonella typhi (271 aa). FASTA: opt: 815 Z-score: 926.6 E(): 1e-43 Smith-Waterman score: 815; 51.020identity in 245 aa overlap. The FASTA-hits do not include the first 220 aa. Probably two genes, metI and metQ, in other organisms. YP_170099.1 Similar to Q83BG9 Tryptophan/tyrosine permease family protein from Coxiella burnetii (426 aa). FASTA: opt: 560 Z-score: 604.8 E(): 8.5e-26 Smith-Waterman score: 560; 27.750identity in 400 aa overlap. ORF ftt1126 YP_170100.1 Similar to Q83F83 Rhodanese domain protein from Coxiella burnetii (124 aa). FASTA: opt: 447 Z-score: 559.4 E(): 2.9e-23 Smith-Waterman score: 447; 51.240 identity in 121 aa overlap. ORF ftt1127 YP_170101.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_170102.1 Similar to CPHA_ANAVA (O86109) Cyanophycin synthetase from Anabaena variabilis (901 aa). FASTA: opt: 2470 Z-score: 2850.7 E(): 6.8e-151 Smith-Waterman score: 2506; 46.787 identity in 887 aa overlap. Probable paralog of cphA since the protein sequences show considerable divergence and gene length differ. ORF ftt1129c YP_170103.1 catalyze the formation of cyanophycin which may act to store excess nitrogen YP_170104.1 Similar to Q83DQ4 Glycerophosphoryl diester phosphodiesterase, (250 aa). FASTA: opt: 306 Z-score: 366.0 E(): 1.7e-12 Smith-Waterman score: 306; 28.916identity in 249 aa overlap. YP_170105.1 Similar to O68431 Pilus assembly protein PilB from Pseudomonas syringae (pv. tomato) (575 aa). FASTA: opt: 1381 Z-score: 1521.6 E(): 7.3e-77 Smith-Waterman score: 1592; 44.597 identity in 583 aa overlap. PilB is required for pili assembly. Homologous to pilT but which has the opposite effect. Homologs exists in other systems. YP_170106.1 Similar to Q888U1 Type IV pilus biogenesis protein PilC from Pseudomonas syringae (pv. tomato) (405 aa). FASTA: opt: 1017 Z-score: 1153.2 E(): 2.4e-56 Smith-Waterman score: 1017; 39.055identity in 402 aa overlap. Termed pilF in N. gonorrhoeae. YP_170107.1 ORF ftt1136c YP_170108.1 ORF ftt1137c YP_170109.1 Similar to HEMZ_RHIME (Q92M52) Ferrochelatase (EC 4.99.1.1) from Rhizobium meliloti (Sinorhizobium meliloti) (339 aa). FASTA: opt: 1069 Z-score: 1243.4 E(): 2.3e-61 Smith-Waterman score: 1069; 48.160 identity in 326 aa overlap. YP_170110.1 ORF ftt1140 YP_170111.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170112.1 ORF ftt1143 YP_170113.1 Similar to Q8XGJ2 Cation transport regulator ChaB from Salmonella typhi (76 aa). FASTA: opt: 267 Z-score: 394.9 E(): 4.2e-14 Smith-Waterman score: 267; 54.412 identity in 68 aa overlap. YP_170114.1 Similar to DFP_HAEIN (P44953) DNA/pantothenate metabolism flavoprotein homolog from Haemophilus influenzae (400 aa). FASTA: opt: 1012 Z-score: 1206.6 E(): 2.6e-59 Smith-Waterman score: 1012; 43.577identity in 397 aa overlap. YP_170115.1 Similar to YJHB_ECOLI (P39352) Hypothetical metabolite transport protein yjhB from Escherichia coli (405 aa). FASTA: opt: 383 Z-score: 393.4 E(): 5.1e-14 Smith-Waterman score: 383; 26.425 identity in 386 aa overlap. YP_170116.1 Similar to Q8XT33 Probable amino-acid permease transmembrane from Ralstonia solanacearum (Pseudomonas solanacearum) (543 aa). FASTA: opt: 960 Z-score: 1077.6 E(): 3.9e-52 Smith-Waterman score: 969; 35.730 identity in 445 aa overlap. ORF ftt1149c YP_170117.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain YP_170118.1 Similar to Q87LM9 Conserved hypothetical protein from Vibrio parahaemolyticus (86 aa). FASTA: opt: 176 Z-score: 242.1 E(): 1.4e-05 Smith-Waterman score: 176; 32.857 identity in 70 aa overlap. ORF ftt1151c YP_170119.1 ORF ftt1152 YP_170120.1 ORF ftt1153c YP_170121.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_170122.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_170123.1 Similar to Q8EK21 Type IV pilus biogenesis protein PilQ from Shewanella oneidensis (684 aa). FASTA: opt: 1014 Z-score: 1145.2 E(): 6.8e-56 Smith-Waterman score: 1014; 31.658 identity in 597 aa overlap. The nearest gene neighbours show similarity to pilN, pilO and pilP. Also required for type II protein secretion. YP_170124.1 Similar to Q8DCM3 Tfp pilus assembly protein PilP from Vibrio vulnificus (170 aa). FASTA: opt: 176 Z-score: 222.1 E(): 0.00018 Smith-Waterman score: 176; 29.921 identity in 127 aa overlap. Weak similarity to the lipoprotein pilP, which appears to be required for stabilisation of pilQ multimer formation. The nearest gene neighbours show similarity to pilN, pilO and pilQ, which indicates that this protein could be pilP ORF ftt1157c YP_170125.1 Similar to Q8PH76 Fimbrial assembly membrane protein from Xanthomonas axonopodis (pv. citri) (221 aa). FASTA: opt: 144 Z-score: 177.4 E(): 0.055 Smith-Waterman score: 144; 25.946 identity in 185 aa overlap. Weak similarity to type IV pili glycosylation protein (pilO). The nearest gene neighbours show similarity to pilN, pilP and pilQ, which indicates that this protein could be pilO. PilO is required for glycosylation of Pseudomonas aeruginosa pilin. ORF ftt1158c YP_170126.1 Similar to Q52540 Membrane protein PilN from Pseudomonas syringae (199 aa). FASTA: opt: 143 Z-score: 182.6 E(): 0.028 Smith-Waterman score: 143; 23.704 identity in 135 aa overlap. The nearest gene neighbours show similarity to pilO, pilP and pilQ, which indicates that this protein could be pilN. PilN is also required for type II protein secretion. ORF ftt1159c YP_170127.1 ORF ftt1160c YP_170128.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_170129.1 ORF ftt1163c YP_170130.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_170131.1 Similar to Q83E19 Aspartate aminotransferase from Coxiella burnetii (394 aa). FASTA: opt: 1067 Z-score: 1292.7 E(): 4.1e-64 Smith-Waterman score: 1067; 41.645 identity in 389 aa overlap. YP_170132.1 Similar to Q8D5X6 Predicted glutamine amidotransferase from Vibrio vulnificus (253 aa). FASTA: opt: 654 Z-score: 813.9 E(): 1.9e-37 Smith-Waterman score: 654; 42.466identity in 219 aa overlap. ORF ftt1166c YP_170133.1 Similar to Q8EE04 (Q8EE04) Conserved hypothetical protein from Shewanella oneidensis (236 aa). FASTA: opt: 349 Z-score: 425.3 E(): 8.5e-16 Smith-Waterman score: 359; 32.273 identity in 220 aa overlap. ORF ftt1167c YP_170134.1 Similar to Q99VS2 NagA protein (Probable N-acetylglucosamine-6-phosphate deacetylase) from Staphylococcus aureus (393 aa). FASTA: opt: 1006 Z-score: 1213.0 E(): 1.1e-59 Smith-Waterman score: 1006; 43.523 identity in 386 aa overlap. YP_170135.1 Similar to Q8EE00 GTP-binding protein (313 aa). FASTA: opt: 793 Z-score: 926.5 E(): 1e-43 Smith-Waterman score: 793; 44.218 identity in 294 aa overlap. ORF ftt1169 YP_170136.1 ORF ftt1170 YP_170137.1 Similar to Q8RN13 HsdM from Campylobacter jejuni (494 aa). FASTA: opt: 2001 Z-score: 2374.3 E(): 2.3e-124 Smith-Waterman score: 2001; 59.719 identity in 499 aa overlap. YP_170138.1 Similar to Q9HSS3 Cold shock protein from Halobacterium sp. (strain NRC-1 / ATCC 700922 / JCM 11081) (74 aa). FASTA: opt: 170 Z-score: 221.1 E(): 0.0002 Smith-Waterman score: 170; 40.323identity in 62 aa overlap. CDS is longer than FASTA matches. Homology is to first 70 aa of protein only and no matches found for 2nd half of CDS YP_170139.1 ORF ftt1174c YP_170140.1 ORF ftt1175c YP_170143.1 Similar to Q9KNJ4 GTP-binding protein TypA from Vibrio cholerae (609 aa). FASTA: opt: 2972 Z-score: 3319.9 E(): 5e-177 Smith-Waterman score: 2972; 73.045identity in 601 aa overlap. YP_170144.1 Similar to Q8EFL9 Gamma-glutamyltranspeptidase from Shewanella oneidensis (579 aa). FASTA: opt: 2002 Z-score: 2308.7 E(): 1.1e-120 Smith-Waterman score: 2002; 54.545 identity in 572 aa overlap. YP_170145.1 Similar to YFCK_ECO57 (Q8XCQ7) Hypothetical protein yfcK from Escherichia coli (668 aa). FASTA: opt: 495 Z-score: 572.0 E(): 5.7e-24 Smith-Waterman score: 495; 28.087 identity in 413 aa overlap. ORF ftt1183c YP_170146.1 Similar to Y369_VIBVU (Q8DF55) Hypothetical protein VV10369 from Vibrio vulnificus (117 aa). FASTA: opt: 238 Z-score: 320.2 E(): 6.1e-10 Smith-Waterman score: 238; 41.304 identity in 92 aa overlap. ORF ftt1184c YP_170147.1 Similar to Q8ZH13 Hypothetical protein YPO1102 from Yersinia pestis (144 aa). FASTA: opt: 463 Z-score: 623.4 E(): 7.9e-27 Smith-Waterman score: 463; 43.662 39dentity in 142 aa overlap. ORF ftt1185c YP_170148.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_170149.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_170150.1 ORF ftt1188 YP_170151.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_170152.1 Similar to Q8RFU4 N-acyl-L-amino acid amidohydrolase from Fusobacterium nucleatum (subsp. nucleatum) (393 aa). FASTA: opt: 945 Z-score: 1170.3 E(): 2.7e-57 Smith-Waterman score: 945; 38.259 identity in 379 aa overlap. ORF ftt1191 YP_170154.1 Similar to Q884M8 Conserved hypothetical protein from Pseudomonas syringae (pv. tomato) (319 aa). FASTA: opt: 460 Z-score: 588.5 E(): 6.9e-25 Smith-Waterman score: 460; 30.435identity in 322 aa overlap. pseudogene (upstream sequence matches homologs). ORF ftt1194c YP_170155.1 Similar to Q9ZC87 Proline/betaine transporter (PROP7) from Rickettsia prowazekii (423 aa). FASTA: opt: 746 Z-score: 810.0 E(): 3.2e-37 Smith-Waterman score: 746; 31.450identity in 407 aa overlap. ORF ftt1196c YP_170156.1 Similar to MURI_NEIMC (Q9RMM3) Glutamate racemase (EC 5.1.1.3) from Neisseria meningitidis (serogroup C) (270 aa). FASTA: opt: 826 Z-score: 958.8 E(): 1.6e-45 Smith-Waterman score: 826; 48.473identity in 262 aa overlap. YP_170157.1 ORF ftt1198c YP_170158.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_170159.1 Similar to Q83BX4 Exodeoxyribonuclease I, from Coxiella burnetii (458 aa). FASTA: opt: 677 Z-score: 797.9 E(): 1.5e-36 Smith-Waterman score: 1190; 39.875 identity in 479 aa overlap. YP_170160.1 Similar to Q9KKP5 Oxidoreductase,short-chain dehydrogenase/reductase family from Vibrio cholerae (239 aa). FASTA: opt: 1097 Z-score: 1344.5 E(): 5.4e-67 Smith-Waterman score: 1097; 72.458identity in 236 aa overlap. ORF ftt1201c YP_170161.1 Similar to Q9KKP4 Transcriptional regulator, LysR family from Vibrio cholerae (301 aa). FASTA: opt: 661 Z-score: 794.3 E(): 2.4e-36 Smith-Waterman score: 661; 36.120identity in 299 aa overlap. ORF ftt1202 YP_170162.1 ORF ftt1203c YP_170163.1 ORF ftt1204c YP_170164.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_170165.1 ORF ftt1206 YP_170166.1 ORF ftt1207 YP_170167.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_170168.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170169.1 CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein ORF ftt1211c YP_170170.1 Similar to LGUL_VIBPA (P46235) Probable lactoylglutathione lyase from Vibrio parahaemolyticus (138 aa). FASTA: opt: 549 Z-score: 759.1 E(): 2.2e-34 Smith-Waterman score: 549; 64.516 identity in 124 aa overlap. YP_170171.1 Similar to YPDP_BACSU (P54163) Hypothetical protein ypdP from Bacillus subtilis (229 aa). FASTA: opt: 472 Z-score: 563.3 E(): 1.7e-23 Smith-Waterman score: 472; 40.435 identity in 230 aa overlap. ORF ftt1213 YP_170172.1 Similar to Q8XN14 Hypothetical protein CPE0524 from Clostridium perfringens (264 aa). FASTA: opt: 486 Z-score: 584.5 E(): 1.1e-24 Smith-Waterman score: 486; 31.939 identity in 263 aa overlap. ORF ftt1214c YP_170173.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_170174.1 ORF ftt1216c YP_170175.1 Similar to Q83F72 VisC protein from Coxiella burnetii (411 aa). FASTA: opt: 645 Z-score: 778.5 E(): 1.8e-35 Smith-Waterman score: 858; 37.192 identity in 406 aa overlap. YP_170176.1 Similar to Q87UH4 2-octaprenyl-6-methoxyphenyl hydroxylase from Pseudomonas syringae (pv. tomato) (395 aa). FASTA: opt: 654 Z-score: 770.5 E(): 5e-35 Smith-Waterman score: 654; 32.143 identity in 392 aa overlap. YP_170177.1 Similar to YGA1_PSEPK (Q88CI0) Hypothetical UPF0149 protein PP5201 from Pseudomonas putida (strain KT2440) (184 aa). FASTA: opt: 269 Z-score: 349.3 E(): 1.4e-11 Smith-Waterman score: 269; 34.637identity in 179 aa overlap. ORF ftt1219c YP_170178.1 Similar to Q8ZM70 ligase from Salmonella typhimurium (182 aa). FASTA: opt: 317 Z-score: 411.1 E(): 5.2e-15 Smith-Waterman score: 317; 32.727 identity in 165 aa overlap. ORF ftt1220 YP_170179.1 ORF ftt1221 YP_170180.1 Similar to Q89YU2 Conserved hypothetical protein, membrane protein from Bacteroides thetaiotaomicron (213 aa). FASTA: opt: 602 Z-score: 702.4 E(): 3.1e-31 Smith-Waterman score: 602; 42.857identity in 210 aa overlap. YP_170181.1 Similar to Q8R8Y8 Hypothetical protein DedA2 from Thermoanaerobacter tengcongensis (209 aa). FAST: opt: 674 Z-score: 828.7 E(): 2.9e-38 Smith-Waterman score: 674; 45.894 identity in 207 aa overlap. YP_170182.1 Similar to RECO_VIBVU (Q8DC74) DNA repair protein recO from Vibrio vulnificus (243 aa). FASTA: opt: 244 Z-score: 288.3 E(): 3.6e-08 Smith-Waterman score: 244; 29.130 identity in 230 aa overlap. YP_170183.1 ORF ftt1225c YP_170184.1 Similar to ISCS_VIBCH (Q9KTY2) Cysteine desulfurase (EC 4.4.1.-) from Vibrio cholerae (404 aa). FASTA: opt: 1104 Z-score: 1336.0 E(): 1.6e-66 Smith-Waterman score: 1104; 45.812 identity in 382 aa overlap. YP_170185.1 Similar to Q9KQG8 Ribonuclease E from Vibrio cholerae (1052 aa). FASTA: opt: 1928 Z-score: 1743.2 E(): 3.3e-89 Smith-Waterman score: 1943; 43.377 identity in 770 aa overlap. YP_170186.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_170187.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_170188.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_170189.1 Similar to Q83BJ9 MesJ protein from Coxiella burnetii (449 aa). FASTA: opt: 639 Z-score: 733.1 E(): 6.1e-33 Smith-Waterman score: 726; 31.387identity in 411 aa overlap. Thought to be a cell cycle protein YP_170190.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170191.1 Similar to YJDL_ECOLI (P39276) Hypothetical transporter yjdL from Escherichia coli (485 aa).FASTA: opt: 1064 Z-score: 1135.9 E(): 2.2e-55 Smith-Waterman score: 1064; 38.222 identity in 450 aa overlap.This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein YP_170192.1 Similar to Q8YIA2 Choloylglycine hydrolase (EC 3.5.1.24) from Brucella melitensis (367 aa). FASTA: opt: 387 Z-score: 460.1 E(): 9.7e-18 Smith-Waterman score: 574; 34.718 identity in 337 aa overlap. ORF ftt1234 YP_170193.1 Similar to Q8FZH8 Lipopolysaccharide core biosynthesis mannosyltransferase LpcC from Brucella suis (354 aa). FASTA: opt: 825 Z-score: 1005.6 E(): 4e-48 Smith-Waterman score: 825; 38.352 identity in 352 aa overlap. YP_170194.1 ORF ftt1236 YP_170195.1 Similar to Q8A3T1 stress protein from Bacteroides thetaiotaomicron (309 aa). FASTA: opt: 308 Z-score: 375.2 E(): 5.2e-13 Smith-Waterman score: 348; 26.599 identity in 297 aa overlap. ORF ftt1237 YP_170196.1 ORF ftt1238c YP_170197.1 ORF ftt1239 YP_170198.2 Similar to YJGA_HAEIN (P45076) Hypothetical protein HI1151 from Haemophilus influenzae (178 aa). FASTA: opt: 359 Z-score: 390.6 E(): 7.3e-14 Smith-Waterman score: 359; 35.928 identity in 167 aa overlap. ORF ftt1240c YP_170199.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_170200.1 ORF ftt1242 YP_170201.1 Similar to EAA32028 Hypothetical protein from Neurospora crassa (567 aa). FASTA: opt: 643 Z-score: 759.7 E(): 2e-34 Smith-Waterman score: 793; 29.879 identity in 579 aa overlap. YP_170202.1 Similar to Q8XYX9 Probable transmembrane protein from Ralstonia solanacearum (Pseudomonas solanacearum) (289 aa). FASTA: opt: 563 Z-score: 689.8 E(): 1.6e-30 Smith-Waterman score: 563; 32.558 identity in 258 aa overlap. YP_170203.1 Similar to Q87S65 Ribosomal large subunit pseudouridine from Vibrio parahaemolyticus (325 aa). FASTA: opt: 917 Z-score: 1118.2 E(): 2.2e-54 Smith-Waterman score: 917; 47.468 identity in 316 aa overlap. YP_170204.1 Similar to Q8EEM6 Bax protein, from Shewanella oneidensis (255 aa). FASTA: opt: 369 Z-score: 448.5 E(): 4.3e-17 Smith-Waterman score: 369; 31.081 identity in 222 aa overlap. ORF ftt1246 YP_170205.1 Similar to Q9A5X9 ABC transporter,permease protein, from Caulobacter crescentus.(371 aa). FASTA: opt: 755 Z-score: 860.3 E(): 5e-40 Smith-Waterman score: 755; 36.095 identity in 338 aa overlap. ORF ftt1247 YP_170206.1 Similar to Q83DK2 ABC transporter,ATP-binding protein from Coxiella burnetii (268 aa). FASTA: opt: 674 Z-score: 783.9 E(): 9e-36 Smith-Waterman score: 674; 46.188 identity in 223 aa overlap. ORF ftt1248 YP_170207.1 Similar to Q9HZ27 Hypothetical protein PA3213 from Pseudomonas aeruginosa (312 aa). FASTA: opt: 282 Z-score: 315.9 E(): 1.1e-09 Smith-Waterman score: 282; 23.661 identity in 224 aa overlap. The archetype (Rv0169) for mce related family proteins, was isolated as being necessary for colonization of, and survival within, the macrophage MEDLINE:93377076. ORF ftt1249 YP_170208.1 ORF ftt1250 YP_170209.1 Similar to Q8EDF8 Conserved hypothetical protein from Shewanella oneidensis (234 aa). FASTA: opt: 692 Z-score: 805.5 E(): 5.6e-37 Smith-Waterman score: 692; 44.828 identity in 232 aa overlap. ORF ftt1251c YP_170210.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_170211.1 Similar to Q9KTB5 Proton/peptide symporter family protein from Vibrio cholerae (514 aa). FASTA: opt: 1234 Z-score: 1376.6 E(): 8.7e-69 Smith-Waterman score: 1245; 42.050identity in 478 aa overlap. ORF ftt1253 YP_170212.1 Similar to Q89UU0 Long-chain-fatty-acid-CoA ligase from Bradyrhizobium japonicum (561 aa). FASTA: opt: 1308 Z-score: 1621.3 E(): 2.1e-82 Smith-Waterman score: 1308; 38.324 identity in 561 aa overlap. YP_170213.1 Similar to Q8PAT1 Transcriptional regulator from Xanthomonas campestris (pv. campestris) (287 aa). FASTA: opt: 689 Z-score: 866.5 E(): 2.3e-40 Smith-Waterman score: 689; 37.354identity in 257 aa overlap. ORF ftt1255c YP_170214.1 Similar to Q83DE1 Drug resistance transporter, EmrB/QacA family from Coxiella burnetii (526 aa). FASTA: opt: 1037 Z-score: 1145.4 E(): 6.6e-56 Smith-Waterman score: 1037; 31.928 identity in 498 aa overlap. YP_170215.1 Similar to Q83DE0 Multidrug resistance protein from Coxiella burnetii (331 aa). FASTA: opt: 742 Z-score: 834.3 E(): 1.4e-38 Smith-Waterman score: 742; 37.695 identity in 321 aa overlap. YP_170216.1 Similar to Q93NK3 outer membrane protein from Pseudomonas syringae (pv. syringae) (475 aa). FASTA: opt: 594 Z-score: 697.2 E(): 6e-31 Smith-Waterman score: 594; 28.970 identity in 466 aa overlap. ORF ftt1258 YP_170217.1 Similar to NADE_MYCPN (P75216) Probable NH(3)-dependent NAD(+) synthetase Mycoplasma pneumoniae (248 aa). FASTA: opt: 601 Z-score: 760.1 E(): 1.9e-34 Smith-Waterman score: 601; 40.928identity in 237 aa overlap. YP_170218.1 ORF ftt1260 YP_170219.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170220.1 Duplicate of FTT0354 and FTT0378. ORF ftt1263c YP_170221.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170222.1 Similar to YC10_PSEAE (Q9I4C8) Hypothetical protein PA1210 from Pseudomonas aeruginosa (232 aa). FASTA: opt: 602 Z-score: 765.5 E(): 9.5e-35 Smith-Waterman score: 602; 41.667 identity in 228 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein. YP_170223.1 Similar to Q8E7Z8 Transcriptional regulator, LysR family from Shewanella oneidensis (289 aa). FASTA: opt: 561 Z-score: 683.5 E(): 3.5e-30 Smith-Waterman score: 561; 32.423identity in 293 aa overlap. ORF ftt1267 YP_170224.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_170225.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_170226.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_170227.1 Similar to Q81ZZ6 membrane-bound lytic murein transglycosylase A transmembrane protein from Nitrosomonas europaea (440 aa). FASTA: opt: 821 Z-score: 989.7 E(): 3.1e-47 Smith-Waterman score: 821; 39.769 identity in 347 aa overlap. YP_170228.1 Similar to Q8KB91 Protoporphyrinogen oxidase, from Chlorobium tepidum (399 aa). FASTA: opt: 594 Z-score: 698.0 E(): 5.5e-31 Smith-Waterman score: 673; 31.552 identity in 393 aa overlap. ORF ftt1272 YP_170229.3 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_170230.2 forms a direct contact with the tRNA during translation YP_170231.1 Similar to O52734 Macrophage growth locus A from Francisella novicida strain U112 (205 aa). FASTA: opt: 1275 Z-score: 1587.7 E(): 1.5e-80 Smith-Waterman score: 1275; 99.512 identity in 205 aa overlap (1-205:1-205). YP_170232.1 Identical to O52735 Macrophage growth locus B from Francisella novicida strain U112 (135 aa). YP_170233.1 Similar to Q88EE1 Sodium-solute symporter, from Pseudomonas putida (strain KT2440) (459 aa). FASTA: opt: 279 Z-score: 311.8 E(): 1.8e-09 Smith-Waterman score: 300; 20.863identity in 417 aa overlap. ORF ftt1277c YP_170234.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_170235.1 Similar to Q8ZCR9 SpoU-family rRNA methylase from Yersinia pestis (257 aa). FASTA: opt: 688 Z-score: 847.8 E(): 2.5e-39 Smith-Waterman score: 688; 47.755 identity in 245 aa overlap. YP_170236.1 Similar to Q88PA0 Phosphotransferase system, nitrogen regulatory IIA protein from Pseudomonas putida (strain KT2440) (154 aa). FASTA: opt: 239 Z-score: 318.2 E(): 7.8e-10 Smith-Waterman score: 239; 26.316identity in 152 aa overlap. YP_170237.1 Similar to RP5M_PSEPK (P15592) Probable sigma(54) modulation protein from Pseudomonas putida (102 aa). FASTA: opt: 336 Z-score: 439.6 E(): 1.4e-16 Smith-Waterman score: 336; 54.839 identity in 93 aa overlap. YP_170238.1 ORF ftt1282 YP_170239.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_170240.1 ORF ftt1284c YP_170241.1 Similar to Q8D448 Transcriptional regulator from Vibrio vulnificus (303 aa). FASTA: opt: 372 Z-score: 436.1 E(): 2.1e-16 Smith-Waterman score: 372; 28.571 identity in 294 aa overlap. ORF ftt1285c YP_170242.1 Similar to Q9BH24 Cystathionine beta-synthase 5 from Trypanosoma cruzi (384 aa). FASTA: opt: 540 Z-score: 651.0 E(): 2.3e-28 Smith-Waterman score: 542; 31.494 identity in 308 aa overlap. YP_170243.1 Similar to Q8Z651 membrane protein from Salmonella typhi (204 aa). FASTA: opt: 462 Z-score: 553.9 E(): 5.9e-23 Smith-Waterman score: 462; 36.667 identity in 180 aa overlap. ORF ftt1288 YP_170245.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_170246.1 Similar to EXUT_BACSU (O34456) Hexuronate transporter from Bacillus subtilis (422 aa). FASTA: opt: 655 Z-score: 716.7 E(): 5e-32 Smith-Waterman score: 659; 28.250 identity in 400 aa overlap. ORF ftt1291 YP_170247.1 Similar to Q88YM1 Hypothetical protein from Lactobacillus plantarum (215 aa). FASTA: opt: 420 Z-score: 532.1 E(): 9.5e-22 Smith-Waterman score: 420; 35.025 identity in 197 aa overlap. ORF ftt1292c YP_170248.1 Similar to Q9KSS8 Hypothetical protein VC1178 from Vibrio cholerae (206 aa). FASTA: opt: 558 Z-score: 715.6 E(): 5.8e-32 Smith-Waterman score: 558; 42.703 identity in 185 aa overlap. ORF ftt1293c YP_170249.1 Similar to ISPZ_RALSO (Q8XYL2) Probable intracellular septation protein from Ralstonia solanacearum (Pseudomonas solanacearum) (186 aa). FASTA: opt: 549 Z-score: 659.0 E(): 8.2e-29 Smith-Waterman score: 549; 38.150 identity in 173 aa overlap. YP_170250.1 Similar to GLK_ANASP (P58616) Glucokinase from Anabaena sp. (strain PCC 7120) (342 aa). FASTA: opt: 735 Z-score: 904.6 E(): 1.7e-42 Smith-Waterman score: 735; 36.735 identity in 343 aa overlap. YP_170251.1 Similar to Q8D1I3 COQ5 methyltransferase from Yersinia pestis (251 aa). FASTA: opt: 1184 Z-score: 1440.7 E(): 2.4e-72 Smith-Waterman score: 1184; 70.800 identity in 250 aa overlap. YP_170252.1 ORF ftt1297 YP_170253.1 Similar to Q83A88 Ubiquinone biosynthesis protein AarF, from Coxiella burnetii (541 aa). FASTA: opt: 1682 Z-score: 2006.3 E(): 7.3e-104 Smith-Waterman score: 1682; 48.269 identity in 520 aa overlap. unrelated to the ABC transporter proteins. YP_170254.1 Similar to Q82WM8 HIT (Histidine triad) family from Nitrosomonas europaea (116 aa). FASTA: opt: 424 Z-score: 574.5 E(): 4.1e-24 Smith-Waterman score: 424; 53.571 identity in 112 aa overlap. YP_170255.1 ORF ftt1300c YP_170256.1 ORF ftt1302 YP_170257.1 ORF ftt1303c YP_170258.1 Similar to MURB_THEMA (Q9X239) UDP-N-acetylenolpyruvoylglucosamine reductase from Thermotoga maritima (284 aa). FASTA: opt: 577 Z-score: 699.7 E(): 4.4e-31 Smith-Waterman score: 577; 39.273 identity in 275 aa overlap. YP_170259.1 Similar to Q814X9 UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Bacillus cereus (strain ATCC 14579 / DSM 31) (434 aa). FASTA: opt: 697 Z-score: 859.3 E(): 5.6e-40 Smith-Waterman score: 765; 33.333 identity in 438 aa overlap. YP_170260.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_170261.1 ORF ftt1307c YP_170262.1 ORF ftt1308c YP_170263.1 Similar to FTSH_ECO57 (Q8X9L0) Cell division protease ftsH from Escherichia coli O157:H7 (644 aa). FASTA: opt: 2569 Z-score: 2823.5 E(): 2.2e-149 Smith-Waterman score: 2569; 60.125 identity in 642 aa overlap. YP_170264.1 Similar to Q8UHQ9 MFS permease from Agrobacterium tumefaciens (strain C58 / ATCC 33970) (475 aa). FASTA: opt: 757 Z-score: 760.1 E(): 1.9e-34 Smith-Waterman score: 766; 32.735 identity in 446 aa overlap. YP_170265.1 Similar to UVRA_PSEAE (Q9HWG0) UvrABC system protein A (UvrA protein) from Pseudomonas aeruginosa (945 aa). FASTA: opt: 4062 Z-score: 4339.5 E():0 Smith-Waterman score: 4062; 63.800identity in 942 aa overlap. YP_170266.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_170267.1 Similar to Q8EBJ4 Type IV pilus biogenesis protein (164 aa). FASTA: opt: 157 Z-score: 204.8 E(): 0.0016 Smith-Waterman score: 157; 27.607 identity in 163 aa overlap. The pili fiber building block protein has a highly distinct primary structure; a short positively charged leader sequence, and a highly conserved and highly hydrophobic amino-terminal domain which forms the core of the pilus fiber; A variety of studies suggest that the invariant glycine (G) at -1 is required for prepilin cleavage and assembly and that the glutamate (E) at + 5 is essential for assembly and efficient N-terminal methylation but not cleavage. The region near the carboxy terminus is often hydrophilic and is stabilized by one or two disulfide bridges that may be involved in recognition of receptors. The genes with these characteristics are usually termed pilA, pilE, pilV, pilW, pilX and FimU. (Mattick John S.. 'Type IV Pili and twitching motility'. Annu. Rev. Microbiol. 2002. 56:289-314.) This protein has all the characteristics described above, except the glutamate (E) at + 5, but shows a weak global homology. ORF ftt1314c YP_170268.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_170269.1 Similar to Q8R9T9 Thiamine pyrophosphokinase from Thermoanaerobacter tengcongensis (211 aa). FASTA: opt: 221 Z-score: 278.6 E(): 1.3e-07 Smith-Waterman score: 238; 25.943 identity in 212 aa overlap. ORF ftt1316c YP_170270.1 Similar to Q88P22 Inosine-5-monophosphate dehydrogenase from Pseudomonas putida (strain KT2440) (489 aa). FASTA: opt: 2187 Z-score: 2403.4 E(): 5.6e-126 Smith-Waterman score: 2187; 68.033 identity in 488 aa overlap. YP_170271.1 Similar to Q887M0 Cytosol aminopeptidase from Pseudomonas syringae (pv. tomato) (496 aa). FASTA: opt: 1161 Z-score: 1388.1 E(): 2e-69 Smith-Waterman score: 1165; 42.540 identity in 496 aa overlap. YP_170272.1 Similar to Q8EH61 Conserved hypothetical protein from Shewanella oneidensis (370 aa). FASTA: opt: 370 Z-score: 433.4 E(): 3e-16 Smith-Waterman score: 370; 21.508 identity in 358 aa overlap. ORF ftt1319 YP_170273.1 Similar to Q8ZK26 permease from Salmonella typhimurium (360 aa). FASTA: opt: 510 Z-score: 585.0 E(): 1.1e-24 Smith-Waterman score: 511; 27.147 identity in 361 aa overlap. ORF ftt1320 YP_170274.1 Similar to Q83AI4 Peptidase, M16 family from Coxiella burnetii (459 aa). FASTA: opt: 868 Z-score: 1053.1 E(): 9.1e-51 Smith-Waterman score: 868; 34.158 identity in 404 aa overlap. ORF ftt1321 YP_170275.1 Similar to Q83AI5 Peptidase, M16 family from Coxiella burnetii (443 aa). FASTA: opt: 605 Z-score: 727.1 E(): 1.3e-32 Smith-Waterman score: 605; 28.607 identity in 402 aa overlap. ORF ftt1322 YP_170276.1 Similar to YHHF_HAEIN (P44869) methylase HI0767 from Haemophilus influenzae (193 aa). FASTA: opt: 455 Z-score: 588.3 E(): 7e-25 Smith-Waterman score: 455; 42.697 identity in 178 aa overlap. ORF ftt1323 YP_170277.1 Similar to Q9CM99 Hypothetical protein PM0935 from Pasteurella multocida (226 aa). FASTA: opt: 523 Z-score: 599.4 E(): 1.7e-25 Smith-Waterman score: 523; 39.151 identity in 212 aa overlap. ORF ftt1324 YP_170278.1 Similar to Q88KV1 TRNA-(ms(2)io(6)a)-hydroxylase, from Pseudomonas putida (strain KT2440)(205 aa). FASTA: opt: 660 Z-score: 867.5 E(): 2e-40 Smith-Waterman score: 660; 50.777 identity in 193 aa overlap. YP_170279.1 Similar to Q9CKN8 Udp from Pasteurella multocida (252 aa). FASTA: opt: 817 Z-score: 1065.9 E(): 1.8e-51 Smith-Waterman score: 817; 48.760 identity in 242 aa overlap. YP_170280.1 Similar to Q8RCG7 Cytidine deaminase from Thermoanaerobacter tengcongensis (135 aa). FASTA: opt: 413 Z-score: 565.4 E(): 1.3e-23 Smith-Waterman score: 413; 52.273 identity in 132 aa overlap. YP_003097805.1 Similar to Q8EDV0 Oxidoreductase,FAD-binding, from Shewanella oneidensis (1013 aa). YP_170281.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_170282.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_170283.1 Similar to Q97IW7 Fructokinase from Clostridium acetobutylicum (288 aa). FASTA: opt: 932 Z-score: 1175.6 E(): 1.4e-57 Smith-Waterman score: 932; 47.603identity in 292 aa overlap. YP_170284.1 Similar to Q9X4C7 Repeat unit exporter from Escherichia coli (419 aa). FASTA: opt: 324 Z-score: 369.2 E(): 1.1e-12 Smith-Waterman score: 324; 22.604 identity in 407 aa overlap. ORF ftt1332 YP_170285.1 ORF ftt1333c YP_170286.1 ORF ftt1334c YP_170287.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_170288.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_170289.1 Similar to DTA2_PSEAE (Q9I4F5) C4-dicarboxylate transport protein from Pseudomonas aeruginosa (436 aa). FASTA: opt: 1534 Z-score: 1703.1 E(): 5.7e-87 Smith-Waterman score: 1534; 55.206identity in 413 aa overlap. YP_170290.1 Similar to Q99WA6 SA0455 protein (Translation initiation inhibitor homologue) from Staphylococcus aureus (126 aa). FASTA: 452 opt: 452 Z-score: 597.7 E(): 2.1e-25 Smith-Waterman score: 452; 61.017 identity in 118 aa overlap. ORF ftt1338c YP_170291.1 Similar to Q87N13 Sulfate permease family protein from Vibrio parahaemolyticus (519 aa). FASTA: opt: 1333 Z-score: 1472.3 E(): 4.1e-74 Smith-Waterman score: 1602; 47.398 identity in 538 aa overlap. ORF ftt1339c YP_170292.1 ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 transposase from Francisella tularensis (247 aa). YP_170293.1 Similiar to CAD85637 (Q82TY8) integral membrane transmembrane protein from Nitrosomonas europaea (221 aa). FASTA: 670 Z-score: 817.1 E(): 1.2e-37 50.226identity in 221 aa overlap ORF ftt1341 YP_170294.1 Similar to Q08861 Gamma-aminobutyric acid-grated chloride- ion channel/receptor, zeta subunit, precusor from Lymnaea stagnalis (437 aa). FASTA: opt: 357 Z-score: 407.4 E(): 7.7e-15 Smith-Waterman score: 360; 23.510 identity in 302 aa overlap ORF ftt1342 YP_170295.1 ORF ftt1343c YP_170296.1 Similar to AAP58968.1 (Q7X3I9) PdpA from Francisella novicida (820 aa). BLAST Score = 1545 bits (4000), Expect = 0.0 Identities = 777/820 (94), Positives = 787/820 (95) Identical to FTT1699. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 YP_170297.1 Similar to AAP58967.1 (Q7X3J0) PdpB from Francisella novicida (1093 aa). BLAST Score = 1914 bits (4959), Expect = 0.0 Identities = 975/1093 (89),Positives = 988/1093 (90) Identical to FTT1700. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 YP_170298.1 Identical to FTT1701. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1346 YP_170299.1 Similar to AAP58969.1 (Q7XI38) unknown protein from Francisella novicida (164 aa). BLAST Score = 305 bits (780), Expect = 2e-82 Identities = 163/164 (99),Positives = 163/164 (99) Identical to FTT1702. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1347 YP_170300.1 1-213 aa similar to AAP58970.1 (Q7X3I7) unknown Francisella novicida (212 aa). BLAST Score 352 ,Expect = 1e-95 Identities = 177/209 (84), Positives = 189/209 (90). 330-580aa similar to AAP58971.1 (Q7X3I6) unknown protein from Francisella tularensis subsp. novicida (251 aa). BLAST Score = 483 bits (1244), Expect = e-135 Identities = 243/251 (96), Positives = 249/251 (99). Identical to FTT1703. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625. Protein fusion product of two hypothetical proteins in F. novicida. ORF ftt1348 YP_170301.1 Similar to AAP58972.1 (Q7X3I5) unknown protein from Francisella novicida (173 aa). BLAST Score = 336, Expect = 1e-91 Identities = 170/173 (98), Positives = 171/173 (98) Identical to FTT1704. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1349 YP_170302.1 Similar to AAP58973.1 (Q7X3I4) unknown protein from Francisella novicida (476 aa). BLAST Score = 864 bits (2233), Expect = 0.0 Identities = 433/476 (90),Positives = 437/476 (91) Identical to FTT1705. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1350 YP_170303.1 Similar to AAP58974.1 (Q7X3I3) unknown protein from Francisella novicida (207 aa). BLAST Score = 391 bits (1005), Expect = e-108 Identities = 194/207 (93),Positives = 195/207 (94) Identical to FTT1706. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1351 YP_170304.1 Similar to AAP58975.1 (Q7X3I2) unknown protein from Francisella novicida (262 aa), BLAST Score = 443 bits (1140), Expect = e-12 Identities = 229/262 (87),Positives = 235/262 (89) This protein is identical to FTT1707. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1352 YP_170305.1 Similar to AAP58976.1 (Q7X3I1) unknown protein from Francisella novicida (257 aa). BLAST Score = 412, Expect = e-114 Identities = 213/257 (82), Positives = 213/257 (82) Identical to FTT1708. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625. ORF ftt1353 YP_170306.1 Similar to AAP58966.1 PdpC from Francisella novicida (1218 aa). BLAST Score = 2172, Expect = 0.0 Identities = 1089/1220 (89), Positives = 1120/1220 (91),Gaps = 3/1220 (0) Identical to FTT1709. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 YP_170307.1 Similar to AAP58977.1 (Q7X3I0) unknown protein from Francisella novicida (188 aa). BLAST Score = 321, Expect = 3e-87 Identities = 156/174 (89), Positives = 162/174 (93) Identical to FTT1710. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 ORF ftt1355 YP_170308.1 Similar to AAP58965.1 (Q7C3J6) IglD from Francisella novicida (398 aa). BLAST Score = 746, Expect = 0.0 Identities = 382/398 (95), Positives = 383/398 (96) Identical to FTT1711. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 YP_170309.1 Similar to AAP58964.1 (Q7X3J5) IglC (23 kDa protein) from Francisella novicida (211 aa). BLAST Score = 405, Expect = e-112 Identities = 209/211 (99), Positives = 210/211 (99) Identical to FTT1712. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 YP_170310.1 Similar to AAP58963.1 (Q7X3J4) IglB from Francisella novicida (514 aa). BLAST Score = 997, Expect = 0.0 Identities = 496/514 (96), Positives = 499/514 (97) Identical to FTT1713. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 YP_170311.1 Similar to AAP58962.1 (Q7X3J5) IglA from Francisella novicida (184 aa). BLAST Score = 350, Expect = 6e-96 Identities = 181/184 (98), Positives = 181/184 (98) Identical to FTT1714. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 YP_170312.1 Similar to AAP58961.1 (Q7C3J6) PdpD from Francisella novicida (1245 aa). BLAST Score = 2194, Expect = 0.0 Identities = 1133/1245 (91), Positives = 1154/1245 (92), Gaps = 50/1245 (4) Identical to FTT1715. It is part of the duplicated region 1374371..1408281 which is identical to 1767715..1801625 YP_170313.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170314.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_170315.1 Similar to AAO91275 (Q83AU7) Pyruvate kinase from Coxiella burnetii (477 aa). FASTA: opt: 1622 Z-score: 1687.6 E(): 3.8e-86 Smith-Waterman score: 1622; 53.249identity in 477 aa overlap domain, score 55.8, E-value 8.1e-14 YP_170316.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_170317.1 Similar to Q8XKT9 Glyceraldehyde-3-phosphate dehydrogenase from Clostridium perfringens (332 aa). FASTA: opt: 1511 Z-score: 1671.9 E(): 2.8e-85 Smith-Waterman score: 1511; 71.341identity in 328 aa overlap YP_170318.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_170319.1 Similar to AAN42711 (Q83LI4) Orf, conserved hypothetical protein from Shigella flexneri (173 aa). FASTA: opt: 194 Z-score: 254.2 E(): 2.6e-06 Smith-Waterman score: 194; 26.708 identity in 161 aa overlap ORF ftt1370 YP_170320.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_170321.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_170322.1 Similar to Q9JW56 3-oxoacyl-[acyl-carrier-protein] synthase III from Neisseria meningitidis (320 aa). FASTA: opt: 1148 Z-score: 1323.1 E(): 7.6e-66 Smith-Waterman score: 1148; 54.859 identity in 319 aa overlap YP_170323.1 Similar to Q9CJS7 FabD from Pasteurella multocida (312 aa). FASTA: opt: 984 Z-score: 1099.0 E(): 2.3e-53 Smith-Waterman score: 984;50.163 identity in 307 aa overlap ORF ftt1374 YP_170324.1 Similar to Q9CJS6 FabG from Pasteurella multocida (242 aa). FASTA: opt: 1029 Z-score: 1192.2 E(): 1.5e-58 Smith-Waterman score: 1029; 66.667 identity in 240 aa overlap YP_170325.1 carries the fatty acid chain in fatty acid biosynthesis YP_170326.1 Similar to Q8Y0J0 Probable 3-oxoacyl-[acyl-carrier-protein] synthase II from Ralstonia solanacearum (410 aa). FASTA: opt: 1679 Z-score: 1887.3 E(): 2.8e-97 Smith-Waterman score: 1679; 59.233 identity in 417 aa overlap YP_170327.1 Similar to P22783 Inositol-1-monophosphatase from E. coli (267 aa). FASTA: opt: 630 Z-score: 759.0 E(): 2e-34 Smith-Waterman score: 656; 36.882identity in 263 aa overlap YP_170328.1 Similar to P44788 SUN protein (FMU protein) from Haemophilus influenzae (451 aa). FASTA: opt: 956 Z-score: 1079.4 E(): 2.9e-52 Smith-Waterman score: 956; 39.401 identity in 434 aa overlap YP_170329.1 Similar to Q8D9X5 Probable acetyltransferase from Vibrio vulnificus (141 aa). FASTA: opt: 183 Z-score: 242.0 E(): 1.3e-05 Smith-Waterman score: 183; 27.132 identity in 129 aa overlap ORF ftt1384c YP_170330.2 ORF ftt1385c YP_170331.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170332.1 Similar to P43813 DNA ligase from Haemophilus influenzae (679 aa). FASTA: opt: 2154 Z-score: 2353.2 E(): 3.2e-123 Smith-Waterman score: 2154; 48.817 identity in 676 aa overlap YP_170333.1 Similar to AAO81619 (Q833S4) Conserved domain protein from Enterococcus faecalis (281 aa). FASTA: opt: 171 Z-score: 214.0 E(): 0.00046 Smith-Waterman score: 194;26.337 identity in 243 aa overlap ORF ftt1388 YP_170334.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_170335.1 Similar to AAO89975 (Q83EA3) Pantoate-beta-alanine ligase from Coxiella burnetii (257 aa). FASTA: opt: 692 Z-score: 830.8 E(): 2e-38 Smith-Waterman score: 692; 40.927 identity in 259 aa overlap YP_170336.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_170337.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_170338.1 Similar to Q9RPH5 RecD from Mycobacterium smegmatis (554 aa). FASTA: opt: 593 Z-score: 627.7 E(): 4.1e-27 Smith-Waterman score: 776; 32.510 identity in 486 aa overlap YP_170339.1 Similar to Q8EF45 Exodeoxyribonuclease V,beta subunit from Shewanella oneidensis (1259 aa). FASTA: opt: 742 Z-score: 770.7 E(): 4.5e-35 Smith-Waterman score: 1544; 30.448identity in 1317 aa overlap YP_170340.1 Similar Q8A303 ATP-dependent DNA helicase from Bacteriodes thetaiotamicron (511 aa). FASTA: opt: 496 Z-score: 533.4 E(): 7.4e-22 Smith-Waterman score: 815; 32.200 identity in 500 aa overlap ORF ftt1395c YP_170341.1 Similar to AAO81663 (Q833N3) Conserved hypothetical protein from Entercoccus faecalis (203 aa). FASTA: opt: 155 Z-score: 198.6 E(): 0.0033 Smith-Waterman score: 155; 25.850 identity in 147 aa overlap ORF ftt1396c YP_170342.1 Similar to P44945 Exodeoxyribonuclease V gamma chain from Haemophilus influenzae (1121 aa). FASTA: opt: 1139 Z-score: 1214.3 E(): 8.7e-60 Smith-Waterman score: 1433; 28.344 identity in 1129 aa overlap YP_170343.1 Similar to Q8KH10 Conserved hypothetical integral membrane (299 aa). FASTA: opt: 516 Z-score: 612.8 E(): 2.8e-26 Smith-Waterman score: 516; 29.818 identity in 275 aa overlap ORF ftt1399 YP_170344.1 ORF ftt1400c YP_170345.1 Similar to Q8HA35 Repressor (217 aa). FASTA: opt: 183 Z-score: 217.7 E(): 0.00028 Smith-Waterman score: 225; 29.167 identity in 216 aa overlap ORF ftt1401 YP_170346.1 ORF ftt1402c YP_170347.1 Similar to P33649 Ferrous iron transport protein A from E. coli (75 aa). FASTA: opt: 148 Z-score: 228.5 E(): 7.1e-05 Smith-Waterman score: 148; 31.081 identity in 74 aa overlap YP_170348.1 Similar to Q8E9Y6 Cell division protein FtsN from Shewanella oneidensis (231 aa). FASTA: opt: 157 Z-score: 187.2 E(): 0.014 Smith-Waterman score: 180; 27.094 identity in 203 aa overlap ORF ftt1404 YP_170349.1 Similar to Q47677 Probable hydroxyacylglutathione hydrolase from E. coli (251 aa). FASTA: opt: 426 Z-score: 519.2 E(): 4.6e-21 Smith-Waterman score: 426; 36.290 identity in 248 aa overlap YP_170350.1 ORF ftt1406c YP_170351.1 ORF ftt1407c YP_170352.1 Similar to Q980U3 Uroporphyrinogen III synthase, from Sulfolobus solfataricus (237 aa). FASTA: opt: 171 Z-score: 213.0 E(): 0.00052 Smith-Waterman score: 171; 34.746 identity in 118 aa overlap YP_170353.1 Similar to Q8PK22 Hypothetical protein from Xanthomonas axonopodis (145 aa). FASTA: opt: 415 Z-score: 523.5 E(): 2.6e-21 Smith-Waterman score: 415; 45.652 identity in 138 aa overlap ORF ftt1409c YP_170354.1 Similar to Q8XTB4 Probable transmembrane protein from Ralstonia solanacearum (184 aa). FASTA: opt: 443 Z-score: 558.2 E(): 3e-23 Smith-Waterman score: 443; 42.045 identity in 176 aa overlap ORF ftt1410 YP_170355.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_170356.1 Similar to Q886Y5 Aminotransferase, classes I and II from Pseudomonas syringae (382 aa). FASTA: opt: 929 Z-score: 1036.9 E(): 6.6e-50 Smith-Waterman score: 929; 37.076 identity in 383 aa overlap ORF ftt1413 YP_170357.1 ORF ftt1414 YP_170358.1 ORF ftt1415 YP_170359.1 ORF ftt1416c YP_170360.1 Similar to Q8ZRJ8 amidohydrolase from Salmonella typhimurium (255 aa). FASTA: opt: 723 Z-score: 882.8 E(): 2.6e-41 Smith-Waterman score: 723; 43.359 identity in 256 aa overlap ORF ftt1417 YP_170361.1 Similar to Q889Q5 N utilization substance protein B from Pseudomonas syringae (165 aa). FASTA: opt: 274 Z-score: 347.8 E(): 1.6e-11 Smith-Waterman score: 274; 32.847 identity in 137 aa overlap YP_170363.1 ORF ftt1420 YP_170364.1 Similar to Q88E79 Conserved hypothetical protein from Pseudomonas putida (150 aa). FASTA: opt: 511 Z-score: 638.2 E(): 1.1e-27 Smith-Waterman score: 511; 46.809 identity in 141 aa overlap ORF ftt1421 YP_170365.1 Similar to Q87UK0 Oxidoreductase, 2OG-Fe(II) oxygenase family (244 aa). FASTA: opt: 400 Z-score: 493.2 E(): 1.3e-19 33.163 identity in 196 aa overlap ORF ftt1422 YP_170366.1 Similar to Q8NQW1 Predicted permease from Corynebacterium glutamicum (250 aa). FASTA: opt: 472 Z-score: 553.4 E(): 5.6e-23 Smith-Waterman score: 472; 35.573 identity in 253 aa overlap. ORF ftt1423c YP_170367.1 Similar to Q89VN8 Bll1007 protein from Bradyrhizobium japonicum (345 aa). FASTA: opt: 834 Z-score: 1018.3 E(): 7.2e-49 Smith-Waterman score: 834; 53.509 identity in 228 aa overlap ORF ftt1424c YP_170368.1 Similar to Q8XMF5 NADH oxidase from Clostridium perfringens (566 aa). FASTA: opt: 2055 Z-score: 2177.9 E(): 1.8e-113 57.117 identity in 548 aa overlap YP_170369.1 Similar to Q8YQC8 Hypothetical protein from Anabaena sp. (177 aa). FASTA: opt: 465 Z-score: 572.2 E(): 5e-24 Smith-Waterman score: 465; 43.023 identity in 172 aa overlap ORF ftt1426c YP_170370.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170371.1 Similar to AAP10414 (Q81AS7) Acetyltransferase from Bacillus cereus (174 aa). FASTA: opt: 372 Z-score: 461.6 E(): 7.3e-18 Smith-Waterman score: 372; 40.341 identity in 176 aa overlap ORF ftt1428c YP_170372.1 Similar Q8DDM9 to threonine efflux protein from Vibrio vulnificus (223 aa). FASTA: opt: 310 Z-score: 386.3 E(): 1.1e-13 Smith-Waterman score: 310; 29.577 identity in 213 aa overlap YP_170373.1 Similar to Q89AR9 inorganic polyphosphate/ATP-NAD kinase from Buchnera aphidicola (292 aa). FASTA: opt: 682 Z-score: 800.3 E(): 1e-36 Smith-Waterman score: 682; 38.776 identity in 294 aa overlap YP_170374.1 Similar to Q55487 glycosyl transferase from Synechocystis sp. (318 aa). FASTA: opt: 1079 Z-score: 1283.0 E(): 1.3e-63 Smith-Waterman score: 1079; 50.000 identity in 298 aa overlap YP_170375.1 Similar Q88LN3 ABC transporter,permease protein from Pseudomonas putida (259 aa). FASTA: opt: 890 Z-score: 979.2 E(): 1.1e-46 Smith-Waterman score: 890; 50.193 identity in 259 aa overlap YP_170376.1 Similar to Q9CNG2 YagD from Pasteurella multocida (312 aa). FASTA: opt: 1028 Z-score: 1082.3 E(): 2e-52 Smith-Waterman score: 1028; 50.662 identity in 302 aa overlap YP_170377.1 ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 transposase from Francisella tularensis (247 aa). YP_170378.1 Similar to Q87N28 deoxyribonuclease from vibrio parahaemolyticus (255 aa). FASTA: opt: 787 Z-score: 917.1 E(): 3.1e-43 Smith-Waterman score: 787; 44.314 identity in 255 aa overlap ORF ftt1439c YP_170379.1 Similar to Q8YQ94 Hypothetical protein from Anabaena sp. (144 aa). FASTA: opt: 497 Z-score: 629.3 E(): 3.4e-27 Smith-Waterman score: 497; 54.610 identity in 141 aa overlap ORF ftt1441 YP_170380.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_170381.1 Similar to Q87ZS7 ATPase, AAA family from Pseudomonas syringae (440 aa). FASTA: opt: 1018 Z-score: 1104.6 E(): 1.1e-53 Smith-Waterman score: 1096; 43.243 identity in 407 aa overlap ORF ftt1443c YP_170382.1 Similar to P44828 exopolyphosphatase from Pneumophilus influenzae (323 aa). FASTA: opt: 730 Z-score: 856.9 E(): 7.1e-40 Smith-Waterman score: 730; 41.275 identity in 298 aa overlap YP_170383.1 Similar to Q9JYY9 Thioredoxin from Neisseria meningitidis (110 aa). FASTA: opt: 452 Z-score: 595.9 E(): 2.4e-25 Smith-Waterman score: 452; 62.000 identity in 100 aa overlap YP_170384.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_170385.1 Similar to Q8UCV4 Phosphomannomutase from Agrobacterium tumefaciens (506 aa). FASTA: opt: 1226 Z-score: 1345.0 E(): 4.6e-67 Smith-Waterman score: 1226; 41.127 identity in 479 aa overlap YP_170386.1 Similar to Q9ETR3 GDP-mannose pyrophosphorylase from Salmonella enterica (464 aa). FASTA: opt: 1571 Z-score: 1720.2 E(): 5.8e-88 Smith-Waterman score: 1571; 50.647 identity in 464 aa overlap YP_170387.1 Similar to Q9RDY1 RmlB protein from Legionella pneumophila (351 aa). FASTA: opt: 1490 Z-score: 1729.8 E(): 1.7e-88 Smith-Waterman score: 1490; 64.392 identity in 337 aa overlap YP_170388.1 Similar to O66250 Glucose-1-phosphate-thymidylyltransferase from Actinobacillus actinomycetemcomitans (290 aa). FASTA: opt: 1336 Z-score: 1567.4 E(): 1.9e-79 Smith-Waterman score: 1336; 67.466 identity in 292 aa overlap YP_170389.1 Similar to Q8ECG2 Glycosyl transferase, group 2 family protein from Shewanella oneidensis (298 aa). FASTA: opt: 724 Z-score: 845.9 E(): 2.9e-39 Smith-Waterman score: 724; 39.789 identity in 284 aa overlap YP_170390.1 Similar to AAO39697(Q84DG4) O antigen flippase from E. coli (464 aa). FASTA: opt: 861 Z-score: 954.5 E(): 2.6e-45 Smith-Waterman score: 861; 31.343identity in 469 aa overlap YP_170391.1 Similar to Q50721 Hypothetical protein Rv3404c precurser from Mycobacterium tuberculosis (234 aa). FASTA: opt: 562 Z-score: 656.5 E(): 1e-28 Smith-Waterman score: 562; 43.243 identity in 185 aa overlap YP_170392.1 Similarity to Q97GL6 Sugar transaminase, involved in dTDP-4-amino-4,6-dideoxyglucose biosynthesis from Clostridium acetobutylicum (364 aa). FASTA: opt: 1344 Z-score: 1521.8 E(): 6.5e-77 Smith-Waterman score: 1344; 59.155 identity in 355 aa overlap YP_170393.1 Similar to Q8GGB6 Asparagine synthase-like protein from Pseudomonas aeruginosa (627 aa). FASTA: opt: 1855 Z-score: 2052.2 E(): 1.9e-106 Smith-Waterman score: 1855; 46.022 identity in 641 aa overlap YP_170394.1 Similar to Q8ECG6 Glycosyl transferase group 1 family protein from Shewanella oneidensis (373 aa). FASTA: opt: 531 Z-score: 625.5 E(): 5.5e-27 Smith-Waterman score: 531; 32.353 identity in 374 aa overlap YP_170395.1 membrane protein/O-antigen polymerase (personal communication from authors) YP_170396.1 Similar to Q8KN66 WbpP from Pseudomonas aeruginosa (341 aa). FASTA: opt: 1033 Z-score: 1225.7 E(): 2e-60 Smith-Waterman score: 1033; 51.562identity in 320 aa overlap YP_170397.1 Similar to Q8EMC3 Vi polysaccharide biosynthesis from Oceanobacillus iheyensis (437 aa). FASTA: opt: 1817 Z-score: 2048.6 E(): 2.9e-106 Smith-Waterman score: 1817; 59.268 identity in 437 aa overlap YP_170398.1 Similar to Q8EMF7 Galacturonosyl transferase from Oceanobacillus iheyensis (362 aa). FASTA: opt: 908 Z-score: 1050.2 E(): 1.2e-50 Smith-Waterman score: 908; 40.223 identity in 358 aa overlap YP_170399.1 Similar to Q9K6L4 UDP-glucose 4-epimerase from Bacillus halodurans (282 aa). FASTA: opt: 758 Z-score: 904.3 E(): 1.6e-42 Smith-Waterman score: 758; 45.455 identity in 264 aa overlap YP_170400.1 Similarity to Q9K6L3 Galactosyltransferase from Bacillus halodurans (207 aa). FASTA: opt: 902 Z-score: 1122.0 E(): 1.2e-54 Smith-Waterman score: 902; 66.667 identity in 195 aa overlap YP_170401.1 Similar to Q9S4V4 PglF from Campylobacter jejuni (590 aa). FASTA: opt: 1343 Z-score: 1435.9 E(): 3.9e-72 Smith-Waterman score: 1378; 43.543identity in 604 aa overlap YP_170402.1 ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 transposase from Francisella tularensis (247 aa). YP_170403.1 Similar to Q8XQG4 L-aspartate oxidase 2 from Ralstonia solanacearum (536 aa). FASTA: opt: 1043 Z-score: 1161.3 E(): 7.8e-57 Smith-Waterman score: 1043; 38.008 identity in 492 aa overlap YP_170404.1 Similar to Q8DC25 Nicotinate-nucleotide pyrophosphorylase from Vibrio vulnificus (295 aa). FASTA: opt: 888 Z-score: 999.5 E(): 8e-48 Smith-Waterman score: 888; 53.737 identity in 281 aa overlap YP_170405.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_170406.1 Essential for recycling GMP and indirectly, cGMP YP_170407.1 Similar to DEAD_KLEPN (P33906) Cold-shock DEAD-box protein A (ATP-dependent RNA helicase deaD) from Klebsiella pneumoniae (642 aa). FASTA: opt: 1669 Z-score: 1759.9 E(): 3.5e-90 Smith-Waterman score: 1669; 45.070 identity in 568 aa overlap YP_170408.1 Identical to Q9ETL6 parvulin ( peptidyl-prolyl cis-trans isomerase) from Francisella tularensis ssp. tularensis strain SchuS4 (FSC237) (92 aa). YP_170409.1 Similar to GALP__ECOLI Galactose-proton symporter from E. coli (464 aa). FASTA: opt: 965 Z-score: 1103.1 E(): 1.4e-53 Smith-Waterman score: 965; 36.226 identity in 461 aa overlap YP_170410.1 Similar to AAO70555 (Q8XEV6) Galactose-proton symport from Salmonella typhimurium (464 aa). FASTA: opt: 1295 Z-score: 1483.7 E(): 8.6e-75 Smith-Waterman score: 1295; 45.140 identity in 463 aa overlap YP_170411.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_170412.1 Similar to GAL1_ACTPL Galactokinase from Actinobacillus pleuropneumoniae (384 aa) FASTA: opt: 959 Z-score: 1098.0 E(): 2.6e-53 Smith-Waterman score: 959; 38.710identity in 372 aa overlap YP_170413.1 Similar to Q88NK0 Conserved hypothetical protein from Pseudomonas putida (139 aa). FASTA: opt: 362 Z-score: 463.4 E(): 5.9e-18 Smith-Waterman score: 362; 40.458 identity in 131 aa overlap ORF ftt1477c YP_170414.2 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_170415.1 Similarity to Q8DAV0 Conserved hypothetical protein from Vibrio vulnificus (59 aa). FASTA: opt: 252 Z-score: 369.5 E(): 1e-12 Smith-Waterman score: 252; 56.140 identity in 57 aa overlap ORF ftt1479c YP_170417.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170418.1 Similar to AAO90013 (Q83E67) Dihydrolipoamide dehydrogenase from Coxiella burnetti (474 aa). FASTA: opt: 2052 Z-score: 2129.3 E(): 9.5e-111 Smith-Waterman score: 2052; 65.890 identity in 472 aa overlap. YP_170419.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_170420.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_170421.1 Similar to AAO91321 (Q83AQ3) Hypothetical protein from Coxiella burnetti (388 aa). FASTA: opt: 858 Z-score: 1007.0 E(): 3.1e-48 Smith-Waterman score: 858 38.504 identity in 361 aa overlap ORF ftt1486c YP_170422.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_170423.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_170424.1 ORF ftt1489 YP_170425.1 Similar to Q9RZK7 NA+/H+ antiporter, , from Deinococcus radiodurans (422 aa). FASTA: opt: 529 Z-score: 612.1 E(): 3.1e-26 Smith-Waterman score: 771; 36.211 identity in 417 aa overlap ORF ftt1490 YP_170428.1 ORF ftt1493c YP_170429.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_170430.1 ORF ftt1495c YP_170431.1 ORF ftt1496c YP_170432.1 ORF ftt1497c YP_170433.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_170434.1 This protein performs the mismatch recognition step during the DNA repair process YP_170435.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_170436.1 Similar to AAP17334 (TRYP_ECOLI) Tyrosine-specific transport protein from E. coli (403 aa). FASTA: opt: 741 Z-score: 839.5 E(): 6.5e-39 Smith-Waterman score: 741; 32.663identity in 398 aa overlap ORF ftt1502 YP_170437.1 Similar to Q88B11 Integrase/recombinase XerC from Pseudomonas syringae (295 aa). FASTA: opt: 790 Z-score: 939.6 E(): 1.7e-44 Smith-Waterman score: 790; 42.177 identity in 294 aa overlap. YP_170438.1 Similar to YHIQ_NEIGO P72077 Hypothetical 27.3kDa protein from Neisseria gonorrhoeae (254 aa). FASTA: opt: 350 Z-score: 423.8 E(): 9.3e-16 Smith-Waterman score: 350; 36.073 identity in 219 aa overlap. ORF ftt1504 YP_170439.1 ORF ftt1505c YP_170440.1 ORF ftt1506 YP_170441.1 ORF ftt1507 YP_170442.1 Similar to Q8EBQ4 GTP pyrophosphokinase from Shewenella oneidensis (735 aa). FASTA: opt: 1566 Z-score: 1723.7 E(): 3.7e-88 Smith-Waterman score: 1639; 39.744 identity in 624 aa overlap YP_170443.1 ORF ftt1509c YP_170444.1 Similar to Q8DAB5 Tyrosine-specific transport protein from Vibrio vulnificus (401 aa). FASTA: opt: 804 Z-score: 930.6 E(): 5.5e-44 Smith-Waterman score: 804; 35.309 identity in 405 aa overlap ORF ftt1510 YP_170445.1 Similar to AAO90839 Membrane protein, from Coxiella burnetii (305 aa). FASTA: opt: 693 Z-score: 824.9 E(): 4.3e-38 Smith-Waterman score: 693; 38.776 identity in 294 aa overlap. ORF ftt1511 YP_170446.1 Similar to CAD85066 (Q82VD9) DnaJ N-terminal domain:DnaJ C terminal domain from Nitrosomonas europaea (314 aa). FASTA opt: 800 Z-score: 823.9 E(): 4.8e-38 39.482 identity in 309 aa overlap. YP_170447.1 ORF ftt1514c YP_170448.1 Similar to Q8XMV7 Hypothetical protein CPE0581 from Clostridium perfrigens (195 aa). FASTA: opt: 348 Z-score: 432.5 E(): 3.1e-16 Smith-Waterman score: 348; 33.333 identity in 189 aa overlap. FTT1563 is more likely to be phosphatidylcoline synthase. ORF ftt1515c YP_170449.1 Similar to Q92KR0 hypothetical transmembrane protein from Rhizobium meliloti (266aa). FASTA: opt: 566 Z-score: 664.8 E(): 3.5e-29 Smith-Waterman score: 566; 40.090 identity in 222 aa overlap. ORF ftt1517c YP_170450.1 Similar to Q8A7W3 methylated-DNA--protein-cysteine methyltransferase from Bacteroides thetaiotaomicron (181aa). FASTA: opt: 443 Z-score: 536.8 bits: 106.7 E(): 4.8e-22 Smith-Waterman score: 443; 44.375 identity in 160 aa overlap. ogt in E.coli is a bifunctional protein containing an autotranscriptional activator at its carboxy domain and a methylated-DNA--protein-cysteine methyltransferase (MGMT) domain at its carboxy terminus. In Bacillus subtilis these two functions are independent and are referred to as adaA and adaB respectively YP_170451.1 Similar to Q8A4M6 glutamate/gamma-aminobutyrate anti-porter from Bacteroides thetaiotaomicron. FASTA: opt: 911 Z-score: 1001.3 E(): 6.4e-48 Smith-Waterman score: 911; 31.696identity in 448 aa overlap. YP_170452.1 Similar to Q8P4A2, hypothetical protein XCC3808 from Xanthamonas campestris (258aa). FASTA: opt:421 Z-score: 521.1 E(): 3.6e-21 Smith-Waterman score: 421; 34.536 identity in 194 aa overlap ORF ftt1522c YP_170453.1 ISFtu2. Transposase, member of the IS5 family. Identical to Q8GM03 transposase from Francisella tularensis (247 aa). YP_170454.1 Similar to Q8ZE61 ATP-dependent helicase from Yersinia pestis (1280 aa). FASTA: opt: 2018 Z-score: 2071.8 E(): 1.5e-107 Smith-Waterman score: 2974; 38.714 identity in 1400 aa overlap YP_170455.1 ORF ftt1525c YP_170456.1 Similar to Q8EDW2 Isocitrate dehydrogenase,NADP-dependent from Shewanella oneidensis (741 aa). FASTA: opt: 3146 Z-score: 3332.9 E(): 8.6e-178 65.574identity in 732 aa overlap YP_170457.1 Similar to Q87MH6 Arsenate reductase from Vibrio parahaemolyticus (116 aa). FASTA: opt: 287 Z-score: 374.9 E(): 5e-13 Smith-Waterman score: 287; 38.739 identity in 111 aa overlap YP_170458.1 Similar to Q8EE09 Long-chain-fatty-acid--CoA ligase from Shewanella oneidensis (557 aa). FASTA: opt: 1556 Z-score: 1747.3 E(): 1.8e-89 Smith-Waterman score: 1556; 42.908identity in 557 aa overlap YP_170459.3 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_170460.1 N-terminal (85 aa) similar to CBP_YEAST (P31787) Acyl-CoA-binding protein (ACBP) from Saccharomyces cerevisiae (86 aa). FASTA opt: 206 Z-score: 281.8 E(): 7.6e-08 Smith-Waterman score: 206; 44.444identity in 72 aa overlap. C-terminus (110-898) similar to Q8P986 3-hydroxacyl-CoA dehydrogenase from Xanthomonas campestris (790 aa). FASTA: opt: 2495 Z-score: 2747.5 E(): 3.5e-145 Smith-Waterman score: 2495;48.228 identity in 790 aa overlap No match to first 110 aa with Q8P986 or any other 3-hydroxacyl-CoA dehydrogenase. Acyl-CoA-binding protein has only been described in eukaryotes unknown EC_number 5.2.2.3 YP_170461.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_170462.1 Similar to Q8ABB1 Conserved hypothetical protein from Bacteriodes thetaiotaomicron (163 aa). FASTA: opt: 237 Z-score: 310.7 E(): 1.9e-09 Smith-Waterman score: 237; 27.097 identity in 155 aa overlap ORF ftt1532 YP_170463.1 Similar to Q8P596 Pre-B cell enhancing factor related protein from Xanthomonas campestris (468 aa). FASTA: opt: 1453 Z-score: 1660.8 E(): 1.2e-84 Smith-Waterman score: 1453; 49.260 identity in 473 aa overlap ORF ftt1534c YP_170464.1 Similar to Q8RGP8 Hypothetical protein from Mycoplasma penetrans (310 aa). FASTA: opt: 805 Z-score: 956.1 E(): 2.1e-45 Smith-Waterman score: 805; 42.308 identity in 312 aa overlap ORF ftt1536c YP_170465.1 Similar to Q8DAW7 Conserved hypothetical protein from Vibrio vulnificus (448 aa). FASTA: opt: 455 Z-score: 511.9 E(): 1.2e-20 Smith-Waterman score: 520; 26.539 identity in 471 aa overlap ORF ftt1537c YP_170466.1 ORF ftt1538c YP_170467.1 Similar to Q9PJ34 periplasmic protein from Campylobacter jejuni (445 aa). FASTA: opt: 520 Z-score: 539.8 E(): 3.2e-22 Smith-Waterman score: 530; 27.673 identity in 477 aa overlap ORF ftt1539c YP_170468.1 Similar to Q8EHZ4 Conserved hypothetical protein from Shewanella oneidensis (197 aa). FASTA: opt: 542 Z-score: 654.0 E(): 1.4e-28 Smith-Waterman score: 542; 41.584 identity in 202 aa overlap ORF ftt1540c YP_170470.1 Similar to Q57483 Outer membrane protein 26 precursor (197 aa). FASTA: opt: 139 Z-score: 159.9 E(): 0.47 Smith-Waterman score: 139; 25.641 identity in 195 aa overlap YP_170471.1 Similar to Q8UGQ7 Two component response regulator from Agrobacterium tumefaciens (252 aa). FASTA: opt: 684 Z-score: 819.7 E(): 8.4e-38 Smith-Waterman score: 684; 45.333 identity in 225 aa overlap ORF ftt1543 YP_170472.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170473.1 ORF ftt1549 YP_170474.1 Similar to Q8EBW9 Conserved hypothetical protein (183 aa). FASTA: opt: 505 Z-score: 618.4 E(): 1.4e-26 Smith-Waterman score: 505; 40.237identity in 169 aa overlap ORF ftt1550 YP_170475.1 Similar to Q888B1 Oxidoreductase,short chain dehydrogenase from Pseudomonas syringae (262 aa). FASTA: opt: 390 Z-score: 468.5 E(): 3e-18 Smith-Waterman score: 445; 32.143 identity in 252 aa overlap ORF ftt1551 YP_170476.1 Similar to Q8PMP8 Delta 9 acyl-lipid fatty acid desaturase from Xanthomonas axonopodis (298 aa). FASTA: opt: 851 Z-score: 1027.5 E(): 2.2e-49 Smith-Waterman score: 851; 45.149identity in 268 aa overlap YP_170477.1 Similar to Q8EAG7 Ribonuclease R from (808 aa). FASTA: opt: 1840 Z-score: 1989.4 E(): 5.9e-103 Smith-Waterman score: 1863; 41.602 identity in 774 aa overlap YP_170478.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_170479.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_170480.1 Similar to AAO90612 9 83CL5) Signal peptidase I from Coxiella burnetii (259 aa). FASTA: opt: 716 Z-score: 839.6 E(): 6.5e-39 Smith-Waterman score: 717; 39.416 identity in 274 aa overlap YP_170481.1 Similar to AAO90736 DNA-binding response regulator from Coxiella burnetii (223 aa). FASTA: opt: 669 Z-score: 771.7 E(): 3.9e-35 Smith-Waterman score: 669; 45.778 identity in 225 aa overlap ORF ftt1557c YP_170482.1 Similar to Q87LJ5 Pyrroline-5-carboxylate reductase from Vibrio parahaemolyticus (272 aa). FASTA: opt: 656 Z-score: 770.0 E(): 4.9e-35 Smith-Waterman score: 656; 39.925identity in 268 aa overlap YP_170483.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_170484.1 Similar to Q87VF9 3-deoxy-D-manno-octulosonic-acid transferase from Pseudomonas syringae (447 aa). FASTA: opt: 1099 Z-score: 1251.3 E(): 7.6e-62 Smith-Waterman score: 1099; 40.143 identity in 421 aa overlap YP_170485.1 Similar to P45204 Geranyltranstransferase from Haemophilus influenzae (295 aa). FASTA: opt: 728 Z-score: 859.4 E(): 5.1e-40 Smith-Waterman score: 728; 43.972 identity in 282 aa overlap YP_170486.1 Similar to O51265 Phosphatidyltransferase from Borrelia burgdorferi (234 aa). FASTA: opt: 438 Z-score: 531.7 E(): 9.1e-22 Smith-Waterman score: 496; 35.743 identity in 249 aa overlap YP_170487.1 Similar to Q9I6Z1 Hypothetical protein PA0141 from Pseudomonas aeruginosa (298 aa). FASTA: opt: 1210 Z-score: 1427.9 E(): 1.1e-71 Smith-Waterman score: 1210; 62.738 identity in 263 aa overlap ORF ftt1564 YP_170489.1 ORF ftt1567c YP_170490.1 Similar to Q87MF0 Lipid-A-disaccharide synthase from Vibrio parahaemolyticus (379 aa). FASTA: 603 opt: 1010 Z-score: 1166.5 E(): 4e-57 Smith-Waterman score: 1010; 41.207 identity in 381 aa overlap YP_170491.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_170492.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_170493.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_170494.1 Similar to OMPH_YEREN Cationic 19 kDa outer membrane protein from Yersinia enterocolitica (169 aa). FASTA: opt: 245 Z-score: 251.8 E(): 3.6e-06 Smith-Waterman score: 245; 28.000 identity in 150 aa overlap YP_170495.1 Similar to Q88MH2 Outer membrane protein,bacterial surface antigen family from Pseudomonas putida (786 aa). FASTA: opt: 1561 Z-score: 1675.2 E(): 1.9e-85 Smith-Waterman score: 1561; 32.959 identity in 801 aa overlap ORF ftt1573c YP_170496.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_170497.1 Similar to GYRA_SALTY (P37411) DNA gyrase subunit A from Salmonella typhimurium (878 aa). FASTA: opt: 3442 Z-score: 3640.6 E(): 6.3e-195 Smith-Waterman score: 3442; 60.665 identity in 872 aa overlap YP_170498.1 ORF ftt1576 YP_170499.1 ORF ftt1577 YP_170500.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_170501.1 Similar to O25314 Type III restriction enzyme R protein from Helicobacter pylori (1001 aa). FASTA: opt: 1491 Z-score: 1485.7 E(): 6.6e-75 Smith-Waterman score: 2480; 42.828 identity in 990 aa overlap ORF ftt1579c YP_170502.1 Identical to AAP83333 Hypothetical protein from Francisella tularensis ssp. tularensis strain SchuS4 (FSC237) (176 aa). ORF ftt1580c YP_170503.1 Similar to Q8DE33 Predicted endonuclease from Vibrio vulnificus (94 aa). FASTA: opt: 387 Z-score: 525.2 E(): 2.1e-21 Smith-Waterman score: 387; 61.798identity in 89 aa overlap ORF ftt1581c YP_170504.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170506.1 ORF ftt1586c YP_170507.1 ORF ftt1589c YP_170508.1 Involved in ubiquinone biosynthesis YP_170509.1 Similar to Q9Z674 Lipoprotein from Zymomonas mobilis (256 aa). FASTA: opt: 352 Z-score: 404.8 E(): 1.1e-14 Smith-Waterman score: 352; 31.739 identity in 230 aa overlap ORF ftt1591 YP_170510.1 Similar to Q8D7C4 Transcriptional regulator from Vibrio vulnificus (301 aa). FASTA: opt: 364 Z-score: 428.7 E(): 5e-16 Smith-Waterman score: 364; 33.010 identity in 206 aa overlap ORF ftt1594 YP_170513.1 ORF ftt1597 YP_170514.1 This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein. ORF ftt1598 YP_170515.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170516.1 Similar to Q87NJ5 Fumarate hydratase, class I from Vibrio parahaemolyticus (505 aa). FASTA: opt: 2398 Z-score: 2635.2 E(): 6.3e-139 Smith-Waterman score: 2398; 69.384 identity in 503 aa overlap YP_170517.1 Similar to Q88C73 ATP-dependent DNA helicase RecG from Pseudomonas putida (692 aa). FASTA: opt: 1698 Z-score: 1867.5 E(): 3.6e-96 Smith-Waterman score: 1698; 41.314 identity in 685 aa overlap YP_170518.1 ORF ftt1602 YP_170519.1 required for 70S ribosome assembly YP_170520.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_170521.1 Similar to Q87RC3 Septum site-determining protein MinC from Vibrio parahaemolyticus (220 aa). FASTA: opt: 444 Z-score: 518.9 E(): 4.7e-21 Smith-Waterman score: 444; 39.196 identity in 199 aa overlap YP_170522.1 Similar to Q8FWX1 Septum site-determining protein MinD from Brucella suis(271 aa). FASTA: opt: 1091 Z-score: 1181.8 E(): 5.6e-58 Smith-Waterman score: 1091; 62.825 identity in 269 aa overlap YP_170523.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_170524.1 Similar to YRBF_HAEIN Probable ABC transporter ATP-binding protein HI1087 from Haemophilus influenzae (264 aa). FASTA: opt: 861 Z-score: 970.8 E(): 3.2e-46 Smith-Waterman score: 861; 50.958identity in 261 aa overlap Equivalent to yrbF of yrb operon in E.coli ORF ftt1608 YP_170525.1 Similar Q8VUQ9 Toluene resistance protein Trg1 from Pseudomonas putida (265 aa). FASTA: opt: 793 Z-score: 934.5 E(): 3.4e-44 Smith-Waterman score: 793; 55.869 identity in 213 aa overlap Equivalent to yrbE of yrb operon in E.coli ORF ftt1609 YP_003097806.1 Similar to YRBD_HAEIN P45029 Hypothetical protein HI1085 from Haemophilus influenzae (167 aa). YP_170526.1 Similar to YRBC_ECOLI Protein yrbC precursor from E. coli (211 aa). FASTA: opt: 230 Z-score: 278.3 E(): 1.2e-07 Smith-Waterman score: 230; 26.147 identity in 218 aa overlap Equivalent to yrbC of yrb operon in E.coli ORF ftt1611 YP_170527.1 Similar to YRBB_ECOLI Hypothetical protein yrbB from E. coli (97 aa). FASTA: opt: 116 Z-score: 165.8 E(): 0.22 Smith-Waterman score: 116; 31.915identity in 47 aa overlap Equivalent to yrbB of yrb operon in E.coli ORF ftt1612 YP_170528.1 Similar to Q8ZB55 BolA-like protein from Yersinia pestis (87 aa). FASTA: opt: 163 Z-score: 236.9 E(): 2.4e-05 Smith-Waterman score: 163; 35.526 identity in 76 aa overlap Equivalent to yrbA of yrb operon in E.coli ORF ftt1613 YP_170530.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170531.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_170532.1 involved in methylation of ribosomal protein L3 YP_170533.2 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170535.1 ORF ftt1622c YP_170538.1 ORF ftt1625c YP_170539.1 ORF ftt1626c YP_170540.1 ORF ftt1627c YP_170541.1 Similar to Q88C61 metal ion transporter from Pseudomonas putida (446 aa). FASTA: opt: 1033 Z-score: 1180.6 E(): 6.5e-58 Smith-Waterman score: 1035; 40.455 identity in 440 aa overlap ORF ftt1628c YP_170542.1 ORF ftt1629c YP_170543.1 Similar to PUTP_ECOLI Sodium/proline symporter from E. coli (501 aa). FASTA: opt: 1536 Z-score: 1735.2 E(): 8.4e-89 Smith-Waterman score: 1536; 46.531identity in 490 aa overlap YP_170544.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_170545.1 Similar to AAO91263 (Q83AV9) Hypothetical protein from Coxiella burnetti (205 aa). FASTA: opt: 552 Z-score: 685.2 E(): 2.6e-30 Smith-Waterman score: 552; 41.000 identity in 200 aa overlap ORF ftt1632c YP_170546.1 Similiar to AAP09999 (Q81BU4) Lysine-specific permease from Bacillus cereus (491 aa). FASTA: opt: 1734 Z-score: 1972.4 bits: 374.4 E(): 5.2e-102 Smith-Waterman score: 1817; 53.459 identity in 477 aa overlap ORF ftt1633c YP_170547.1 ORF ftt1634c YP_170548.1 Similar to Q9I0M3 Cell division protein FtsK from Rickettsia prowazekii (811 aa). FASTA: opt: 2030 Z-score: 2059.0 E(): 7.7e-107 Smith-Waterman score: 2197; 45.808 identity in 823 aa overlap YP_170549.1 Similar to LOLA_PSEAE (Q9I0M4) Outer-membrane lipoproteins carrier from Pseudomonas aeruginosa (208 aa). FASTA: opt: 384 Z-score: 440.9 E(): 1e-16 Smith-Waterman score: 384; 30.476 identity in 210 aa overlap YP_170550.1 ORF ftt1637c YP_170551.1 Similar to Q9KNI3 Potassium uptake protein TrkH from Vibrio cholerae (485 aa). FASTA: opt: 1470 Z-score: 1682.5 E(): 7.3e-86 Smith-Waterman score: 1470; 43.827 identity in 486 aa overlap YP_170552.1 ORF ftt1639c YP_170553.1 Similar to O86076 Sucrose hydrolase from E. coli (477 aa). FASTA: opt: 787 Z-score: 912.8 E(): 5.4e-43 Smith-Waterman score: 787; 31.929 identity in 451 aa overlap ORF ftt1644 YP_170554.1 Similar to Q8EDM5 Conserved hypothetical protein from Shewanella oneidensis (384 aa). FASTA: opt: 372 Z-score: 419.7 E(): 1.6e-15 Smith-Waterman score: 372; 23.018 identity in 391 aa overlap ORF ftt1645 YP_170556.1 Similar to Q9WYG8 Dihydroorotate dehydrogenase from Pyrobaculum aerophilum (297 aa). FASTA: opt: 148 Z-score: 178.6 E(): 0.043 Smith-Waterman score: 191; 26.568 identity in 271 aa overlap YP_170557.1 Similar to PYRF_STAAM (Q9LCT0) Orotidine 5'-phosphate decarboxylase from Bradyrhizobium japonicum (237 aa). FASTA: opt: 228 z-score: 280.6 E(): 8.8e-08 Smith-Waterman score: 243; 28.061identity in 196 aa overlap YP_170558.1 Similar to Q93LJ4 Periplasmic monofunctional chorismate mutase from Salmonella typhimurium (181 aa). FASTA: opt: 186 Z-score: 223.0 E(): 0.00014 Smith-Waterman score: 186; 31.746 identity in 126 aa overlap ORF ftt1650 YP_170559.1 Similar to Q8KDD5 Hypothetical protein from Chlorobium tepidum (215 aa). FASTA: opt: 569 z-score: 706.8 E(): 1.6e-31 Smith-Waterman score: 569; 40.580 identity in 207 aa overlap ORF ftt1651 YP_170560.1 Similar to Q8EFC8 Transcriptional regulator, LysR family from Shewanella oneidensis (291 aa). FASTA: opt: 443 Z-score: 527.9 E(): 1.5e-21 Smith-Waterman score: 443; 29.831 identity in 295 aa overlap ORF ftt1652c YP_170561.1 ORF ftt1653 YP_170562.1 Similar to AAO90332 (Q83DE0) Multidrug resistance protein from Coxiella burnetii (331 aa). FASTA: opt: 406 z-score: 447.9 E(): 4.2e-17 Smith-Waterman score: 406; 28.135 identity in 327 aa overlap YP_170563.1 ORF ftt1655 YP_170564.1 Similiar to Q8PGE2 Hypothetical protein from Xanthomonas axonopodis(186 aa). FASTA: opt: 578 Z-score: 703.0 E(): 2.6e-31 Smith-Waterman score: 578; 51.462 identity in 171 aa overlap ORF ftt1656c YP_170566.1 Similar to BAC68773 (Q82P70) Hypothetical protein from Streptomyces avermitilis (95 aa). FASTA: opt: 135 Z-score: 188.6 E(): 0.012 Smith-Waterman score: 135; 25.316 identity in 79 aa overlap ORF ftt1658c YP_170567.1 ORF ftt1659 YP_170568.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_170569.1 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide YP_170570.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_170571.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_170572.1 Similar to PYRB_METJA Aspartate carbamoyltransferase from Methanococcus jannaschii (306 aa). FASTA: opt: 943 Z-score: 1081.5 E(): 2.2e-52 Smith-Waterman score: 943; 49.338 identity in 302 aa overlap YP_170573.1 Similar to AAP10961 (Q819E3) 3-hydroxyisobutyrate dehydrogenase from Bacillus cereus (292 aa). FASTA: opt: 384 z-score: 452.2 E(): 2.4e-17 Smith-Waterman score: 384; 24.483 identity in 290 aa overlap ORF ftt1666c YP_170574.1 ORF ftt1667 YP_170575.1 Similar to Q8ZGH6 Serine transporter from Yersinia pestis (433 aa). FASTA: opt: 1336 Z-score: 1510.1 E(): 2.9e-76 Smith-Waterman score: 1336; 46.078identity in 408 aa overlap. YP_170576.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170577.1 Similar to RIBD_AQUAE Riboflavin biosynthesis protein ribD from Aquiflex aeolicus (356 aa). FASTA: opt: 915 z-score: 1060.1 E(): 3.4e-51 Smith-Waterman score: 916; 43.824 identity in 340 aa overlap YP_170578.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_170579.1 Similar to GCH2_AQUAE Riboflavin biosynthesis protein ribA from Aquiflex aeolicus (406 aa). FASTA: opt: 1135 z-score: 1316.5 E(): 1.8e-65 Smith-Waterman score: 1135; 46.305 identity in 406 aa overlap YP_170580.1 Similar to AAO90192 (Q83DP8) Riboflavin synthase, beta subunit from Coxiella burnetii (151 aa). FASTA: opt: 496 z-score: 645.4 E(): 4.2e-28 Smith-Waterman score: 496; 53.571 identity in 140 aa overlap YP_170581.1 Similar to DEF_NEIMA (Q9JQN0) Peptide deformylase from Neisseria meningitidis (167 aa). FASTA: opt: 465 z-score: 571.7 E(): 5.4e-24 Smith-Waterman score: 465; 46.914 identity in 162 aa overlap YP_170582.1 ORF ftt1676 YP_170583.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_170584.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_170585.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_170586.1 Similar to Q8KTI1 Outer membrane lipoprotein OmlA from Azaobacter vinelandii (171 aa). FASTA: opt: 208 Z-score: 273.7 E(): 2.1e-07 Smith-Waterman score: 208; 30.392 identity in 102 aa overlap YP_170587.1 Similar to Q8EK08 Phosphoheptose isomerase from Shewanella oneidensis (197 aa). FASTA: opt: 705 z-score: 847.8 E(): 2.3e-39 Smith-Waterman score: 705; 53.684 identity in 190 aa overlap YP_170588.1 Similar to Q8NM37 Permeases of the major facilitator superfamily from Corynebacterium glutamicum (398 aa). FASTA: opt: 440 z-score: 489.8 E(): 2e-19 Smith-Waterman score: 440; 24.211 identity in 380 aa overlap ORF ftt1683c YP_170589.1 Similar to Q8D3N4 Transcriptional regulator from Vibrio vulnificus (307 aa). FASTA: opt: 510 Z-score: 590.3 E(): 5e-25 32.975 identity in 279 aa overlap ORF ftt1684 YP_170591.1 Similar to Q894C5 Proline synthetase associated protein from Clostridium tetani (225 aa). FASTA: opt: 462 z-score: 549.8 E(): 8.9e-23 37.220 identity in 223 aa overlap ORF ftt1686c YP_170592.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_170593.1 Similar to Q8EFB8 Tyrosine-specific transport protein from Shewanella oneidensis (395 aa). FASTA: opt: 854 z-score: 967.0 E(): 5.2e-46 38.378 identity in 370 aa overlap ORF ftt1688 YP_170594.1 Similar to CAD84514 (Q82WQ9) Possible transmembrane protein from Nitrosomonas europaea (223 aa). FASTA: opt: 294 z-score: 358.6 E(): 4e-12 25.481 identity in 208 aa overlap ORF ftt1689c YP_170595.1 Similar to Q9ABA7 NADH dehydrogenase from Caulobacter crescentus (220 aa). FASTA: opt: 429 z-score: 535.0 E(): 6e-22 35.545 identity in 211 aa overlap ORF ftt1690 YP_170596.1 This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein. ORF ftt1691 YP_170621.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170598.1 Similar to Q87SC0 conserved hypothetical protein from Vibrio parahaemolyticus (258 aa). FASTA: opt: 724 z-score: 845.1 E(): 3.2e-39 46.094 identity in 256 aa overlap ORF ftt1693c YP_170599.1 Similar to Q8ZCK6 membrane protein (Hypothetical) from Yersinia pestis (175 aa). FASTA: opt:353 z-score 450 E():2.9e-17 35.9identity in 142 aa overlap ORF ftt1694c YP_170600.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_170601.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_170602.2 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170603.1 Similar to FDH_PSESR Formate dehydrogenase from Pseudomonas sp. (strain 101) (400 aa). FASTA: opt: 1074 z-score: 1253.7, E(): 5.5e-62, 66.949 identity in 236 aa overlap. This CDS is disrupted by the insertion of an ISFtu1 element occurring very near the C-terminal end. It is not clear whether this insertion affects the function of the protein. YP_170604.1 Similar to AAP58968.1 (Q7X3I9) PdpA from Francisella novicida (820 aa). BLAST Score = 1545 bits (4000), Expect = 0.0 Identities = 777/820 (94), Positives = 787/820 (95). Identical to FTT1344. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 YP_170605.1 Similar to AAP58967.1 (Q7X3J0) PdpB from Francisella novicida (1093 aa). BLAST Score = 1914 bits (4959), Expect = 0.0 Identities = 975/1093 (89),Positives = 988/1093 (90). This protein is identical to FTT1345. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..140828 YP_170606.1 Identical to FTT1346. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1701 YP_170607.1 Similar to AAP58969.1 (Q7XI38) unknown protein from Francisella novicida (164 aa). BLAST Score = 305 bits (780), Expect = 2e-82 Identities = 163/164 (99),Positives = 163/164 (99). Identical to FTT1347. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1702 YP_170608.1 1-213 aa similar to AAP58970.1 (Q7X3I7) unknown Francisella novicida (212 aa). BLAST Score 352 ,Expect = 1e-95 Identities = 177/209 (84), Positives = 189/209 (90). 330-580 aa similar to AAP58971.1 (Q7X3I6) unknown protein from Francisella tularensis subsp. novicida (251 aa). BLAST Score = 483 bits (1244), Expect = e-135 Identities = 243/251 (96), Positives = 249/251 (99). Identical to FTT1348. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281. Protein fusion product of two hypothetical proteins in F. novicida. ORF ftt1703 YP_170609.1 Similar to AAP58972.1 (Q7X3I5) unknown protein from Francisella novicida (173 aa). BLAST Score = 336, Expect = 1e-91 Identities = 170/173 (98), Positives = 171/173 (98). Identical to FTT1349. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1704 YP_170610.1 Similar to AAP58973.1 (Q7X3I4) unknown protein from Francisella novicida (476 aa). BLAST Score = 864 bits (2233), Expect = 0.0 Identities = 433/476 (90),Positives = 437/476 (91). Identical to FTT1350. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1705 YP_170611.1 Similar to AAP58974.1 (Q7X3I3) unknown protein from Francisella novicida (207 aa). BLAST Score = 391 bits (1005), Expect = e-108 Identities = 194/207 (93),Positives = 195/207 (94). Identical to FTT1351. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1706 YP_170612.1 Similar to AAP58975.1 (Q7X3I2) unknown protein from Francisella novicida (262 aa), BLAST Score = 443 bits (1140), Expect = e-12 Identities = 229/262 (87),Positives = 235/262 (89). Identical to FTT1352. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1707 YP_170613.1 Similar to AAP58976.1 (Q7X3I1) unknown protein from Francisella novicida (257 aa). BLAST Score = 412, Expect = e-114 Identities = 213/257 (82), Positives = 213/257 (82). Identical to FTT1353. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1708 YP_170614.1 Similar to AAP58966.1 PdpC from Francisella novicida (1218 aa). BLAST Score = 2172, Expect = 0.0 Identities = 1089/1220 (89), Positives = 1120/1220 (91),Gaps = 3/1220 (0). Identical to FTT1354. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 YP_170615.1 Similar to AAP58977.1 (Q7X3I0) unknown protein from Francisella novicida (188 aa). BLAST Score = 321, Expect = 3e-87 Identities = 156/174 (89), Positives = 162/174 (93). Identical to FTT1355. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 ORF ftt1710 YP_170616.1 Similar to AAP58965.1 (Q7C3J6) IglD from Francisella novicida (398 aa). BLAST Score = 746, Expect = 0.0 Identities = 382/398 (95), Positives = 383/398 (96) Identical to FTT1356. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 YP_170617.1 Similar to AAP58964.1 (Q7X3J5) IglC from Francisella novicida (23 kDa protein) (211 aa). BLAST Score = 405,Expect = e-112 Identities = 209/211 (99), Positives = 210/211 (99). Identical to FTT1357. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 YP_170618.1 Similar to AAP58963.1 (Q7X3J4) IglB from Francisella novicida (514 aa). BLAST Score = 997, Expect = 0.0 Identities = 496/514 (96), Positives = 499/514 (97). Identical to FTT1358. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 YP_170619.1 Similar to AAP58962.1 (Q7X3J5) IglA from Francisella novicida (184 aa). BLAST Score = 350, Expect = 6e-96 Identities = 181/184 (98), Positives = 181/184 (98). Identical to FTT1359. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 YP_170620.1 Similar to AAP58961.1 (Q7C3J6) PdpD from Francisella novicida (1245 aa). BLAST Score = 2194, Expect = 0.0 Identities = 1133/1245 (91), Positives = 1154/1245 (92), Gaps = 50/1245 (4). Identical to FTT1360. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281 YP_170638.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170622.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_170623.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_170624.1 Similar to Q8FHG5 Glutamate decarboxylase beta from E. coli (489 aa). FASTA: opt: 1709 Z-score: 1968.5 bits: 373.6 E(): 8.6e-102 Smith-Waterman score: 1709; 57.011 identity in 435 aa overlap YP_170625.1 Similar to GSP_BACBR (P40683) 4'-phosphopantetheinyl transferase from Bacillus brevis (237 aa). FASTA: opt: 224 Z-score: 292.3 E(): 2.2e-08 Smith-Waterman score: 224; 33.929 identity in 112 aa overlap ORF ftt1723c YP_170626.1 Similar to TOLC_ECOLI (P02930) Outer membrane protein tolC precursor from E. coli (495 aa). FASTA: opt: 548 Z-score: 649.7 E(): 2.7e-28 Smith-Waterman score: 548; 28.000 identity in 425 aa overlap YP_170627.1 Similar to Q9JXU0 Protein-L-isoaspartate O-methyltransferase from Neisseria meningitidis (218 aa). FASTA: opt: 335 Z-score: 438.9 E(): 1.5e-16 Smith-Waterman score: 335; 33.659 identity in 205 aa overlap YP_170628.1 Similar to YEGQ_ECOLI (P76403) protease yegQ from E. coli (453 aa). FASTA: opt: 1828 Z-score: 2215.7 E(): 1.6e-115 Smith-Waterman score: 1828; 61.745identity in 447 aa overlap Truncated ortholog (188 aa) previously reported in Schu as O68834 Hypothetical 21.3 kDa protein and AAC12939 unknown YP_170629.1 Similar to Q83CE1 Drug resistance transporter, Bcr/CflA family from Coxiella burnetii (398 aa). FASTA: opt: 957 Z-score: 1006.0 E(): 3.8e-48 Smith-Waterman score: 957; 38.542identity in 384 aa overlap ORF ftt1727c YP_170630.1 Similar to Q8D4S6 Na+/H+ antiporter NhaD from Vibrio vulnificus (478 aa). FASTA: opt: 1428 Z-score: 1679.2 E(): 1.2e-85 Smith-Waterman score: 1592; 50.617identity in 486 aa overlap YP_170631.1 Similar to Q97MC6 Amino acid transporter from Clostridium acetobutylicum (620 aa). FASTA: opt: 1338 Z-score: 1514.2 E(): 1.9e-76 Smith-Waterman score: 1338; 37.745 identity in 612 aa overlap ORF ftt1730c YP_170632.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_170633.1 Similar to Q8FGM8 Tyrosine-specific transport protein from E. coli (403 aa). FASTA: opt: 724 Z-score: 839.2 E(): 6.8e-39 Smith-Waterman score: 724; 35.638 identity in 376 aa overlap ORF ftt1732 YP_170635.1 Similar to Q8U9E1 Two component sensor kinase from Agrobacterium tumefaciens (900 aa). FASTA: opt: 1625 Z-score: 1777.7 E(): 3.6e-91 Smith-Waterman score: 1625; 32.745 identity in 907 aa overlap YP_170636.1 Similar to Q8R8I7 K+-transporting ATPase, c chain from Thermoanaerobacter tengcogenesis (193 aa). FASTA: opt: 404 Z-score: 471.4 E(): 2.1e-18 Smith-Waterman score: 404; 43.333identity in 180 aa overlap YP_170637.1 Similar to ATKB_RHIME (Q92XJ0) Potassium-transporting ATPase B chain from Rhizobium meliloti (680 aa). FASTA: opt: 2393 Z-score: 2638.7 E(): 4.4e-139 Smith-Waterman score: 2393; 55.490 identity in 683 aa overlap YP_170649.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170639.1 Similar to Q8TT45 Indolepyruvate decarboxylase Methanosarcina activorans (550 aa). FASTA: opt: 1265 Z-score: 1467.5 E(): 7.6e-74 Smith-Waterman score: 1265; 36.909 identity in 550 aa overlap YP_170640.1 Similar to Q87YG1 Signal peptide peptidase SppA, 36K type from Pseudomonas syringae (332 a). FASTA: opt: 839 Z-score: 1007.2 E(): 3.3e-48 Smith-Waterman score: 839; 46.622 identity in 296 aa overlap ORF ftt1746 YP_170641.1 Similar to AAO90156 (Q83DT1) Outer membrane protein OmpH, , from Coxiella burnetii (165 aa). FASTA: opt: 175 Z-score: 183.6 E(): 0.022 Smith-Waterman score: 216; 26.816 identity in 179 aa overlap ORF ftt1747 YP_170642.1 Similar to AAO91018 (Q83BI7) Rhodanese domain protein Coxiella burnetii (144 aa). FASTA: opt: 279 Z-score: 342.5 E(): 3.5e-11 Smith-Waterman score: 279; 33.094 identity in 139 aa overlap YP_170643.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_170644.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_170645.1 Similar to RECX_HAEIN (P43706) Regulatory protein recX from Haemophilus influenzae (126 aa). FASTA: opt: 243 Z-score: 314.3 E(): 1.3e-09 Smith-Waterman score: 243; 31.967 identity in 122 aa overlap YP_170646.1 Similar to SSB_HAEIN P44409 Single-strand binding protein (SSB) from Haemophilus influenzae (168 aa). FASTA: opt: 437 Z-score: 543.8 E(): 1.9e-22 Smith-Waterman score: 437; 44.578identity in 166 aa overlap YP_170647.1 Similar to ACKA_CLOTS (Q59331) Acetate kinase (Acetokinase) from Clostridium thermosaccharolyticum (400 aa). FASTA: opt: 1204 Z-score: 1394.5 E(): 8e-70 Smith-Waterman score: 1204; 49.873 identity in 395 aa overlap YP_170648.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_170668.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170650.1 Similar to Q8D0W2 cytochrome from Yersinia pestis (199 aa). FASTA: opt: 273 Z-score: 328.7 E(): 1.9e-10 Smith-Waterman score: 273; 27.979identity in 193 aa overlap ORF ftt1758c YP_170651.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_170652.1 Similar to YAFD_ECOLI (P30865) Hypothetical protein yafD from E. coli (266 aa). FASTA: opt: 320 Z-score: 403.2 E(): 1.5e-14 Smith-Waterman score: 320; 34.498 identity in 229 aa overlap ORF ftt1761 YP_170653.1 Similar to Q9F728 N-acylhomoserine lactone synthase from Pseudomonas fluorescens (259 aa). FASTA: opt: 408 Z-score: 521.4 E(): 3.8e-21 Smith-Waterman score: 408; 34.498 identity in 229 aa overlap ORF ftt1762c YP_170654.1 Similar to Q9F728 N-acylhomoserine lactone syntase from Pseudomonas fluorescens (259 aa). FASTA: opt: 442 Z-score: 546.9 E(): 1.4e-22 Smith-Waterman score: 442; 37.963 identity in 216 aa overlap. ORF ftt1763c YP_170655.1 Similar to FER_PSEST (P08811) Ferredoxin from Pseudomonas stutzeri (106 aa). FASTA: opt: 535 Z-score: 674.6 E(): 1.1e-29 Smith-Waterman score: 535; 65.714identity in 105 aa overlap ORF ftt1764c YP_170656.1 ORF ftt1765 YP_170657.1 Similar to Q8YLW7 O-methyltransferase from Anabaena sp. (220 aa). FASTA: opt: 622 Z-score: 791.6 E(): 3.4e-36 Smith-Waterman score: 622; 43.836identity in 219 aa overlap ORF ftt1766 YP_170658.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_170659.1 Similar to Q9KQP6 Chitinase from Vibrio cholerae (846 aa). FASTA: opt: 242 Z-score: 272.3 E(): 2.8e-07 Smith-Waterman score: 279; 21.309 identity in 718 aa overlap. ORF ftt1768c YP_170660.1 Similar to FASTA: AAO89660 (Q83F55) ClpB protein from Coxiella burnetii (859 aa). FASTA: opt: 3593 Z-score: 3223.6 E(): 1.1e-171 Smith-Waterman score: 3593; 65.357 identity in 840 aa overlap YP_170661.1 ORF ftt1771 YP_170662.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_170663.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_170664.1 Similar to CLCA_ECOLI (P37019) Voltage-gated ClC-type chloride channel from E. coli (473 aa). FASTA: opt: 1120 Z-score: 1211.7 E(): 1.3e-59 Smith-Waterman score: 1120; 39.545 identity in 440 aa overlap YP_170665.1 ORF ftt1776c YP_170666.1 ORF ftt1777c YP_170667.1 ORF ftt1778c YP_003097807.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. Identical to Q93EJ6 transposase from Francisella tularensis (118 aa) from aa 144-261. Identical to Q93EJ7 transposase from Francisella tularensis (126 aa) from aa 1-109. Q93EJ6 and Q93EJ7 previously characterised as two separate ORF's. ORF1 (identical to Q93EJ7) contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' at aa position 109 which permits frameshifting to ORF2 (identical to Q93EJ6) to produce a single ORF. Alignment of this single ORF with additional members of the IS630 family, and also mariner elements, show that this transposase shares strongly conserved residues, including a fully conserved dipeptide,Asp-Glu (DE), and a block consisting of a fully conserved Asp and highly conserved Glu, separated by 34 or 35 residues (D35E). The conserved dipeptide is only present if ribosomal frameshifting occurs. YP_170669.1 ORF ftt1781c YP_170670.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_170671.1 Similar to Q83A52 Major facilitator family transporter from Coxiella burnetii (443 aa). FASTA: opt: 751 Z-score: 809.6 E(): 3.3e-37 Smith-Waterman score: 751; 34.204identity in 421 aa overlap ORF ftt1783 YP_170672.1 ORF ftt1784c YP_170673.1 ORF ftt1785c YP_170674.1 Similar to Q8UGV8 LysE family transporter from Agrobactium tumifaciens (202 aa). FASTA: opt: 346 Z-score: 414.9 E(): 3.2e-15 Smith-Waterman score: 346; 30.102 identity in 196 aa overlap ORF ftt1787c YP_170675.1 Similar to Q83C04 Membrane protein, , from Coxiella burnetii (263 aa). FASTA: opt: 496 Z-score: 540.4 E(): 3.3e-22 Smith-Waterman score: 496; 30.038 identity in 263 aa overlap ORF ftt1789 YP_170676.1 ORF ftt1791 YP_170677.1 Similar to AMPN_ECOLI (P04825) Aminopeptidase N from E. coli (869 aa). FASTA: opt: 2226 Z-score: 2532.9 E(): 3.4e-133 Smith-Waterman score: 2751; 48.856identity in 874 aa overlap YP_170678.1 Similar to Q9WYK7 Heat shock protein, class I from Thermatoga maritima (147 aa). FASTA: opt: 288 Z-score: 346.4 E(): 2.1e-11 Smith-Waterman score: 288; 37.879 identity in 132 aa overlap ORF ftt1794 YP_170679.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_170680.1 Similar to Q9KF27 Hypothetical protein BH0670 from Bacillus halodurans (159 aa). FASTA: opt: 208 Z-score: 278.0 E(): 1.4e-07 Smith-Waterman score: 208; 28.682 identity in 129 aa overlap ORF ftt1796c YP_170681.1 Similar to MSA2_CAUCR (Q9A9E9) Peptide methionine sulfoxide reductase from Caulobacter crescentus (196 aa). FASTA opt: 510 Z-score: 598.2 E(): 2e-25 Smith-Waterman score: 510; 39.024 identity in 205 aa overlap YP_170682.1 ORF ftt1798c YP_170683.1 ORF ftt1800c YP_170684.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_170685.1 Similar to TRPR_ECOLI (P03032) Trp operon repressor from E. coli (107 aa). FASTA: opt: 175 Z-score: 239.1 E(): 2e-05 Smith-Waterman score: 175; 32.584 identity in 89 aa overlap YP_170686.1 Similar to RNG_ECOLI (P25537) Ribonuclease G from E. coli (488 aa). FASTA: opt: 1439 Z-score: 1642.1 E(): 1.4e-83 Smith-Waterman score: 1439; 45.418 identity in 491 aa overlap