-- dump date 20140619_095709 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001121138.1 134301170 4959650 46..1521 1 NC_009257.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1521 dnaA 4959650 dnaA Francisella tularensis subsp. tularensis WY96-3418 chromosomal replication initiation protein YP_001121138.1 46 D 418136 CDS YP_001121139.1 134301171 4959116 1558..2661 1 NC_009257.1 DNA polymerase III subunit beta 2661 dnaN 4959116 dnaN Francisella tularensis subsp. tularensis WY96-3418 DNA polymerase III subunit beta YP_001121139.1 1558 D 418136 CDS YP_001121140.1 134301172 4960055 complement(join(3108..3659,3659..3988)) 1 NC_009257.1 ORF00005 has a programmed ribosomal frameshift 'aaaaaaag' which permits frameshifting to ORF00004 to produce a single ORF with high sequence similarity to IS630 family of insertion elements; programmed frameshift; transposase ISFtu1 3988 4960055 FTW_0004 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121140.1 3108 R 418136 CDS YP_001121141.1 134301173 4959099 4789..5181 1 NC_009257.1 lipoprotein 5181 4959099 FTW_0007 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001121141.1 4789 D 418136 CDS YP_001121142.1 134301174 4958931 5202..5612 1 NC_009257.1 hypothetical protein 5612 4958931 FTW_0008 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121142.1 5202 D 418136 CDS YP_001121143.1 134301175 4958855 5615..6013 1 NC_009257.1 hypothetical protein 6013 4958855 FTW_0009 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121143.1 5615 D 418136 CDS YP_001121144.1 134301176 4958886 6084..7502 1 NC_009257.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 7502 clcA 4958886 clcA Francisella tularensis subsp. tularensis WY96-3418 chloride channel protein YP_001121144.1 6084 D 418136 CDS YP_001121145.1 134301177 4958800 7519..8943 1 NC_009257.1 metallocarboxypeptidase 8943 4958800 FTW_0011 Francisella tularensis subsp. tularensis WY96-3418 metallocarboxypeptidase YP_001121145.1 7519 D 418136 CDS YP_001121146.1 134301178 4958734 9030..10220 1 NC_009257.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 10220 trpB 4958734 trpB Francisella tularensis subsp. tularensis WY96-3418 tryptophan synthase subunit beta YP_001121146.1 9030 D 418136 CDS YP_001121147.1 134301179 4959277 10220..11029 1 NC_009257.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 11029 trpA 4959277 trpA Francisella tularensis subsp. tularensis WY96-3418 tryptophan synthase subunit alpha YP_001121147.1 10220 D 418136 CDS YP_001121148.1 134301180 4958832 complement(11084..11437) 1 NC_009257.1 hypothetical protein 11437 4958832 FTW_0014 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121148.1 11084 R 418136 CDS YP_001121149.1 134301181 4958910 12455..15034 1 NC_009257.1 AAA ATPase 15034 clpB 4958910 clpB Francisella tularensis subsp. tularensis WY96-3418 AAA ATPase YP_001121149.1 12455 D 418136 CDS YP_001121150.1 134301182 4958719 17532..18692 1 NC_009257.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 18692 purT 4958719 purT Francisella tularensis subsp. tularensis WY96-3418 phosphoribosylglycinamide formyltransferase 2 YP_001121150.1 17532 D 418136 CDS YP_001121151.1 134301183 4958831 complement(18694..19350) 1 NC_009257.1 O-methyltransferase family protein 19350 4958831 FTW_0021 Francisella tularensis subsp. tularensis WY96-3418 O-methyltransferase family protein YP_001121151.1 18694 R 418136 CDS YP_001121152.1 134301184 4958993 complement(19428..20069) 1 NC_009257.1 hypothetical protein 20069 4958993 FTW_0022 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121152.1 19428 R 418136 CDS YP_001121153.1 134301185 4959416 20301..20624 1 NC_009257.1 4Fe-4S ferredoxin 20624 4959416 FTW_0023 Francisella tularensis subsp. tularensis WY96-3418 4Fe-4S ferredoxin YP_001121153.1 20301 D 418136 CDS YP_001121154.1 134301186 4958891 20787..21539 1 NC_009257.1 acetyltransferase protein 21539 4958891 FTW_0024 Francisella tularensis subsp. tularensis WY96-3418 acetyltransferase protein YP_001121154.1 20787 D 418136 CDS YP_001121155.1 134301187 4958986 21553..22293 1 NC_009257.1 acetyltransferase protein 22293 4958986 FTW_0025 Francisella tularensis subsp. tularensis WY96-3418 acetyltransferase protein YP_001121155.1 21553 D 418136 CDS YP_001121156.1 134301188 4959352 complement(22299..23018) 1 NC_009257.1 hypothetical protein 23018 4959352 FTW_0026 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121156.1 22299 R 418136 CDS YP_001121157.1 134301189 4958961 complement(23083..24234) 1 NC_009257.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 24234 nhaA 4958961 nhaA Francisella tularensis subsp. tularensis WY96-3418 pH-dependent sodium/proton antiporter YP_001121157.1 23083 R 418136 CDS YP_001121158.1 134301190 4958853 24328..25224 1 NC_009257.1 Rieske (2Fe-2S) domain-containing protein 25224 4958853 FTW_0028 Francisella tularensis subsp. tularensis WY96-3418 Rieske (2Fe-2S) domain-containing protein YP_001121158.1 24328 D 418136 CDS YP_001121159.1 134301191 4959350 25290..25799 1 NC_009257.1 putative B-type cytochrome subunit 25799 4959350 FTW_0029 Francisella tularensis subsp. tularensis WY96-3418 putative B-type cytochrome subunit YP_001121159.1 25290 D 418136 CDS YP_001121160.1 134301192 4959304 join(27236..27565,27565..28116) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 28116 4959304 FTW_0033 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121160.1 27236 D 418136 CDS YP_001121161.1 134301193 4959373 30375..33962 1 NC_009257.1 pathogenicity determinant protein D, pdpD 33962 pdpD1 4959373 pdpD1 Francisella tularensis subsp. tularensis WY96-3418 pathogenicity determinant protein D, pdpD YP_001121161.1 30375 D 418136 CDS YP_001121162.1 134301194 4959157 34043..34597 1 NC_009257.1 intracellular growth locus, igl A 34597 iglA1 4959157 iglA1 Francisella tularensis subsp. tularensis WY96-3418 intracellular growth locus, igl A YP_001121162.1 34043 D 418136 CDS YP_001121163.1 134301195 4958938 34611..36131 1 NC_009257.1 intracellular growth locus B, IglB 36131 iglB1 4958938 iglB1 Francisella tularensis subsp. tularensis WY96-3418 intracellular growth locus B, IglB YP_001121163.1 34611 D 418136 CDS YP_001121164.1 134301196 4959295 36142..36777 1 NC_009257.1 intracellular growth locus iglC 36777 iglC1 4959295 iglC1 Francisella tularensis subsp. tularensis WY96-3418 intracellular growth locus iglC YP_001121164.1 36142 D 418136 CDS YP_001121165.1 134301197 4959255 36798..37994 1 NC_009257.1 intracellular growth locus iglD 37994 iglD1 4959255 iglD1 Francisella tularensis subsp. tularensis WY96-3418 intracellular growth locus iglD YP_001121165.1 36798 D 418136 CDS YP_001121166.1 134301198 4959384 complement(38001..38576) 1 NC_009257.1 hypothetical protein 38576 4959384 FTW_0042 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121166.1 38001 R 418136 CDS YP_001121167.1 134301199 4959594 complement(38594..42580) 1 NC_009257.1 pathogenicity determinant protein pdpC 42580 pdpC1 4959594 pdpC1 Francisella tularensis subsp. tularensis WY96-3418 pathogenicity determinant protein pdpC YP_001121167.1 38594 R 418136 CDS YP_001121168.1 134301200 4959646 complement(42620..43336) 1 NC_009257.1 hypothetical protein 43336 4959646 FTW_0044 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121168.1 42620 R 418136 CDS YP_001121169.1 134301201 4959802 complement(43359..44510) 1 NC_009257.1 hypothetical protein 44510 4959802 FTW_0045 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121169.1 43359 R 418136 CDS YP_001121170.1 134301202 4959778 complement(44532..45155) 1 NC_009257.1 hypothetical protein 45155 4959778 FTW_0046 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121170.1 44532 R 418136 CDS YP_001121171.1 134301203 4959914 complement(45168..46598) 1 NC_009257.1 hypothetical protein 46598 4959914 FTW_0047 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121171.1 45168 R 418136 CDS YP_001121172.1 134301204 4959886 complement(46611..47132) 1 NC_009257.1 hypothetical protein 47132 4959886 FTW_0048 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121172.1 46611 R 418136 CDS YP_001121173.1 134301205 4959984 complement(47133..48863) 1 NC_009257.1 hypothetical protein 48863 4959984 FTW_0049 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121173.1 47133 R 418136 CDS YP_001121174.1 134301206 4959946 complement(48868..49362) 1 NC_009257.1 hypothetical protein 49362 4959946 FTW_0050 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121174.1 48868 R 418136 CDS YP_001121175.1 134301207 4958727 complement(49375..49752) 1 NC_009257.1 lipoprotein 49752 4958727 FTW_0051 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001121175.1 49375 R 418136 CDS YP_001121176.1 134301208 4960190 complement(49742..53023) 1 NC_009257.1 pathogenicity deteminant protein pdpB1 53023 pdpB1 4960190 pdpB1 Francisella tularensis subsp. tularensis WY96-3418 pathogenicity deteminant protein pdpB1 YP_001121176.1 49742 R 418136 CDS YP_001121177.1 134301209 4960224 complement(53028..55490) 1 NC_009257.1 pathogenicity deteminant protein pdpA1 55490 pdpA1 4960224 pdpA1 Francisella tularensis subsp. tularensis WY96-3418 pathogenicity deteminant protein pdpA1 YP_001121177.1 53028 R 418136 CDS YP_001121178.1 134301210 4960237 join(61855..62184,62184..62735) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 62735 4960237 FTW_0056 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121178.1 61855 D 418136 CDS YP_001121179.1 134301211 4960300 63486..65207 1 NC_009257.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 65207 kdpA 4960300 kdpA Francisella tularensis subsp. tularensis WY96-3418 potassium-transporting ATPase subunit A YP_001121179.1 63486 D 418136 CDS YP_001121180.1 134301212 4960070 65217..67256 1 NC_009257.1 K+-transporting ATPase subunit B 67256 kdpB 4960070 kdpB Francisella tularensis subsp. tularensis WY96-3418 K+-transporting ATPase subunit B YP_001121180.1 65217 D 418136 CDS YP_001121181.1 134301213 4960474 67273..67827 1 NC_009257.1 potassium-transporting ATPase C chain 67827 kdpC 4960474 kdpC Francisella tularensis subsp. tularensis WY96-3418 potassium-transporting ATPase C chain YP_001121181.1 67273 D 418136 CDS YP_001121182.1 134301214 4958700 67931..70612 1 NC_009257.1 two component sensor protein KdpD 70612 kdpD 4958700 kdpD Francisella tularensis subsp. tularensis WY96-3418 two component sensor protein KdpD YP_001121182.1 67931 D 418136 CDS YP_001121183.1 134301215 4959039 71556..72035 1 NC_009257.1 hypothetical protein 72035 4959039 FTW_0064 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121183.1 71556 D 418136 CDS YP_001121184.1 134301216 4960522 72482..73678 1 NC_009257.1 tryptophan/tyrosine permease family protein 73678 4960522 FTW_0065 Francisella tularensis subsp. tularensis WY96-3418 tryptophan/tyrosine permease family protein YP_001121184.1 72482 D 418136 CDS YP_001121185.1 134301217 4960528 73754..74758 1 NC_009257.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 74758 obgE 4960528 obgE Francisella tularensis subsp. tularensis WY96-3418 GTPase ObgE YP_001121185.1 73754 D 418136 CDS YP_001121186.1 134301218 4960531 74765..76639 1 NC_009257.1 amino acid transporter 76639 4960531 FTW_0067 Francisella tularensis subsp. tularensis WY96-3418 amino acid transporter YP_001121186.1 74765 D 418136 CDS YP_001121187.1 134301219 4960481 complement(78291..79718) 1 NC_009257.1 Na+/H+ antiporter 79718 nhaD 4960481 nhaD Francisella tularensis subsp. tularensis WY96-3418 Na+/H+ antiporter YP_001121187.1 78291 R 418136 CDS YP_001121188.1 134301220 4959521 79893..81074 1 NC_009257.1 major facilitator superfamily multidrug resistance protein 81074 4959521 FTW_0071 Francisella tularensis subsp. tularensis WY96-3418 major facilitator superfamily multidrug resistance protein YP_001121188.1 79893 D 418136 CDS YP_001121189.1 134301221 4959610 complement(81115..82446) 1 NC_009257.1 peptidase, U32 family protein 82446 4959610 FTW_0072 Francisella tularensis subsp. tularensis WY96-3418 peptidase, U32 family protein YP_001121189.1 81115 R 418136 CDS YP_001121190.1 134301222 4959801 82766..83386 1 NC_009257.1 putative protein-L-isoaspartate O-methyltransferase 83386 4959801 FTW_0073 Francisella tularensis subsp. tularensis WY96-3418 putative protein-L-isoaspartate O-methyltransferase YP_001121190.1 82766 D 418136 CDS YP_001121191.1 134301223 4959817 83395..84924 1 NC_009257.1 TolC family outer membrane efflux protein 84924 4959817 FTW_0074 Francisella tularensis subsp. tularensis WY96-3418 TolC family outer membrane efflux protein YP_001121191.1 83395 D 418136 CDS YP_001121192.1 134301224 4959851 84933..85574 1 NC_009257.1 4'-phosphopantetheinyl transferase 85574 4959851 FTW_0075 Francisella tularensis subsp. tularensis WY96-3418 4'-phosphopantetheinyl transferase YP_001121192.1 84933 D 418136 CDS YP_001121193.1 134301225 4959869 85585..86931 1 NC_009257.1 glutamate decarboxylase 86931 4959869 FTW_0076 Francisella tularensis subsp. tularensis WY96-3418 glutamate decarboxylase YP_001121193.1 85585 D 418136 CDS YP_001121194.1 134301226 4959912 87025..88515 1 NC_009257.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 88515 purF 4959912 purF Francisella tularensis subsp. tularensis WY96-3418 amidophosphoribosyltransferase YP_001121194.1 87025 D 418136 CDS YP_001121195.1 134301227 4959933 88515..92387 1 NC_009257.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 92387 purL 4959933 purL Francisella tularensis subsp. tularensis WY96-3418 phosphoribosylformylglycinamidine synthase YP_001121195.1 88515 D 418136 CDS YP_001121196.1 134301228 4959270 join(92947..93276,93276..93827) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 93827 4959270 FTW_0081 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121196.1 92947 D 418136 CDS YP_001121197.1 134301229 4959436 95466..96305 1 NC_009257.1 aldose 1-epimerase family protein 96305 4959436 FTW_0086 Francisella tularensis subsp. tularensis WY96-3418 aldose 1-epimerase family protein YP_001121197.1 95466 D 418136 CDS YP_001121198.1 134301230 4959628 complement(96279..97106) 1 NC_009257.1 hypothetical protein 97106 4959628 FTW_0087 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121198.1 96279 R 418136 CDS YP_001121199.1 134301231 4959709 complement(97349..97747) 1 NC_009257.1 hypothetical protein 97747 4959709 FTW_0088 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121199.1 97349 R 418136 CDS YP_001121200.1 134301232 4959745 98075..99373 1 NC_009257.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 99373 purB 4959745 purB Francisella tularensis subsp. tularensis WY96-3418 adenylosuccinate lyase YP_001121200.1 98075 D 418136 CDS YP_001121201.1 134301233 4959776 99407..99985 1 NC_009257.1 hypothetical protein 99985 4959776 FTW_0090 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121201.1 99407 D 418136 CDS YP_001121202.1 134301234 4959781 100072..101613 1 NC_009257.1 antibiotic ABC transporter 101613 4959781 FTW_0091 Francisella tularensis subsp. tularensis WY96-3418 antibiotic ABC transporter YP_001121202.1 100072 D 418136 CDS YP_001121203.1 134301235 4959823 101624..102694 1 NC_009257.1 membrane fusion protein 102694 4959823 FTW_0092 Francisella tularensis subsp. tularensis WY96-3418 membrane fusion protein YP_001121203.1 101624 D 418136 CDS YP_001121204.1 134301236 4959392 102777..103058 1 NC_009257.1 Glu-tRNAGln amidotransferase C subunit 103058 gatC 4959392 gatC Francisella tularensis subsp. tularensis WY96-3418 Glu-tRNAGln amidotransferase C subunit YP_001121204.1 102777 D 418136 CDS YP_001121205.1 134301237 4959842 103067..104512 1 NC_009257.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 104512 gatA 4959842 gatA Francisella tularensis subsp. tularensis WY96-3418 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_001121205.1 103067 D 418136 CDS YP_001121206.1 134301238 4959826 104515..105936 1 NC_009257.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 105936 gatB 4959826 gatB Francisella tularensis subsp. tularensis WY96-3418 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_001121206.1 104515 D 418136 CDS YP_001121207.1 134301239 4959913 105951..106358 1 NC_009257.1 hypothetical protein 106358 4959913 FTW_0096 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121207.1 105951 D 418136 CDS YP_001121208.1 134301240 4959978 complement(107913..109442) 1 NC_009257.1 hypothetical protein 109442 4959978 FTW_0100 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121208.1 107913 R 418136 CDS YP_001121209.1 134301241 4960012 complement(109528..110718) 1 NC_009257.1 major facilitator transporter 110718 figD 4960012 figD Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001121209.1 109528 R 418136 CDS YP_001121210.1 134301242 4960031 complement(110734..111987) 1 NC_009257.1 diaminopimelate decarboxylase 111987 figC 4960031 figC Francisella tularensis subsp. tularensis WY96-3418 diaminopimelate decarboxylase YP_001121210.1 110734 R 418136 CDS YP_001121211.1 134301243 4960057 complement(111980..113242) 1 NC_009257.1 major facilitator transporter 113242 figB 4960057 figB Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001121211.1 111980 R 418136 CDS YP_001121212.1 134301244 4960086 complement(113249..115168) 1 NC_009257.1 IucA/IucC family siderophore biosynthesis protein 115168 figA 4960086 figA Francisella tularensis subsp. tularensis WY96-3418 IucA/IucC family siderophore biosynthesis protein YP_001121212.1 113249 R 418136 CDS YP_001121213.1 134301245 4960472 complement(115423..115845) 1 NC_009257.1 ferric uptake regulation protein 115845 fur 4960472 fur Francisella tularensis subsp. tularensis WY96-3418 ferric uptake regulation protein YP_001121213.1 115423 R 418136 CDS YP_001121214.1 134301246 4960103 116054..116452 1 NC_009257.1 NADH dehydrogenase I subunit A 116452 nuoA 4960103 nuoA Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase I subunit A YP_001121214.1 116054 D 418136 CDS YP_001121215.1 134301247 4960147 116443..116919 1 NC_009257.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 116919 nuoB 4960147 nuoB Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase subunit B YP_001121215.1 116443 D 418136 CDS YP_001121216.1 134301248 4960181 116922..117566 1 NC_009257.1 NADH dehydrogenase I subunit C 117566 nuoC 4960181 nuoC Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase I subunit C YP_001121216.1 116922 D 418136 CDS YP_001121217.1 134301249 4960219 117588..118841 1 NC_009257.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 118841 nuoD 4960219 nuoD Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase subunit D YP_001121217.1 117588 D 418136 CDS YP_001121218.1 134301250 4958770 118851..119339 1 NC_009257.1 NADH dehydrogenase I subunit E 119339 nuoE 4958770 nuoE Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase I subunit E YP_001121218.1 118851 D 418136 CDS YP_001121219.1 134301251 4958789 119346..120620 1 NC_009257.1 NADH dehydrogenase I subunit F 120620 nuoF 4958789 nuoF Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase I subunit F YP_001121219.1 119346 D 418136 CDS YP_001121220.1 134301252 4959424 120638..123004 1 NC_009257.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 123004 nuoG 4959424 nuoG Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase subunit G YP_001121220.1 120638 D 418136 CDS YP_001121221.1 134301253 4959459 123006..124016 1 NC_009257.1 NADH dehydrogenase I subunit H 124016 nuoH 4959459 nuoH Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase I subunit H YP_001121221.1 123006 D 418136 CDS YP_001121222.1 134301254 4958745 124030..124518 1 NC_009257.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 124518 nuoI 4958745 nuoI Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase subunit I YP_001121222.1 124030 D 418136 CDS YP_001121223.1 134301255 4958857 124523..125128 1 NC_009257.1 NADH dehydrogenase I subunit J 125128 nuoJ 4958857 nuoJ Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase I subunit J YP_001121223.1 124523 D 418136 CDS YP_001121224.1 134301256 4958871 125121..125438 1 NC_009257.1 NADH dehydrogenase I subunit K 125438 nuoK 4958871 nuoK Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase I subunit K YP_001121224.1 125121 D 418136 CDS YP_001121225.1 134301257 4958879 125448..127457 1 NC_009257.1 NADH dehydrogenase I subunit L 127457 nuoL 4958879 nuoL Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase I subunit L YP_001121225.1 125448 D 418136 CDS YP_001121226.1 134301258 4958882 127483..129072 1 NC_009257.1 NADH dehydrogenase I subunit M 129072 nuoM 4958882 nuoM Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase I subunit M YP_001121226.1 127483 D 418136 CDS YP_001121227.1 134301259 4958968 129088..130539 1 NC_009257.1 NADH dehydrogenase I subunit N 130539 nuoN 4958968 nuoN Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase I subunit N YP_001121227.1 129088 D 418136 CDS YP_001121228.1 134301260 4959085 130615..130809 1 NC_009257.1 hypothetical protein 130809 4959085 FTW_0120 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121228.1 130615 D 418136 CDS YP_001121229.1 134301261 4959273 132372..133406 1 NC_009257.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 133406 hemE 4959273 hemE Francisella tularensis subsp. tularensis WY96-3418 uroporphyrinogen decarboxylase YP_001121229.1 132372 D 418136 CDS YP_001121230.1 134301262 4959691 133632..134084 1 NC_009257.1 hypothetical protein 134084 4959691 FTW_0124 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121230.1 133632 D 418136 CDS YP_001121231.1 134301263 4959323 134102..135571 1 NC_009257.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 135571 nusA 4959323 nusA Francisella tularensis subsp. tularensis WY96-3418 transcription elongation factor NusA YP_001121231.1 134102 D 418136 CDS YP_001121232.1 134301264 4959448 135610..138141 1 NC_009257.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 138141 infB 4959448 infB Francisella tularensis subsp. tularensis WY96-3418 translation initiation factor IF-2 YP_001121232.1 135610 D 418136 CDS YP_001121233.1 134301265 4959066 138144..138575 1 NC_009257.1 ribosome-binding factor A 138575 rbfA 4959066 rbfA Francisella tularensis subsp. tularensis WY96-3418 ribosome-binding factor A YP_001121233.1 138144 D 418136 CDS YP_001121234.1 134301266 4959393 138583..139848 1 NC_009257.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 139848 hisS 4959393 hisS Francisella tularensis subsp. tularensis WY96-3418 histidyl-tRNA synthetase YP_001121234.1 138583 D 418136 CDS YP_001121235.1 134301267 4959267 139855..141153 1 NC_009257.1 major facilitator transporter 141153 4959267 FTW_0129 Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001121235.1 139855 D 418136 CDS YP_001121236.1 134301268 4958908 141156..142223 1 NC_009257.1 AFG1 family ATPase 142223 4958908 FTW_0130 Francisella tularensis subsp. tularensis WY96-3418 AFG1 family ATPase YP_001121236.1 141156 D 418136 CDS YP_001121237.1 134301269 4958927 142216..143145 1 NC_009257.1 ribosomal large subunit pseudouridine synthase C 143145 rluC 4958927 rluC Francisella tularensis subsp. tularensis WY96-3418 ribosomal large subunit pseudouridine synthase C YP_001121237.1 142216 D 418136 CDS YP_001121238.1 134301270 4959239 complement(143147..144451) 1 NC_009257.1 major facilitator transporter 144451 4959239 FTW_0132 Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001121238.1 143147 R 418136 CDS YP_001121239.1 134301271 4960232 144528..144959 1 NC_009257.1 hypothetical protein 144959 4960232 FTW_0133 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121239.1 144528 D 418136 CDS YP_001121240.1 134301272 4958995 145012..145803 1 NC_009257.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 145803 atpB 4958995 atpB Francisella tularensis subsp. tularensis WY96-3418 F0F1 ATP synthase subunit A YP_001121240.1 145012 D 418136 CDS YP_001121241.1 134301273 4959103 145854..146159 1 NC_009257.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 146159 atpE 4959103 atpE Francisella tularensis subsp. tularensis WY96-3418 F0F1 ATP synthase subunit C YP_001121241.1 145854 D 418136 CDS YP_001121242.1 134301274 4958982 146205..146675 1 NC_009257.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 146675 atpF 4958982 atpF Francisella tularensis subsp. tularensis WY96-3418 F0F1 ATP synthase subunit B YP_001121242.1 146205 D 418136 CDS YP_001121243.1 134301275 4958738 146695..147219 1 NC_009257.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 147219 atpH 4958738 atpH Francisella tularensis subsp. tularensis WY96-3418 F0F1 ATP synthase subunit delta YP_001121243.1 146695 D 418136 CDS YP_001121244.1 134301276 4958963 147238..148779 1 NC_009257.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 148779 atpA 4958963 atpA Francisella tularensis subsp. tularensis WY96-3418 F0F1 ATP synthase subunit alpha YP_001121244.1 147238 D 418136 CDS YP_001121245.1 134301277 4959177 148794..149690 1 NC_009257.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 149690 atpG 4959177 atpG Francisella tularensis subsp. tularensis WY96-3418 F0F1 ATP synthase subunit gamma YP_001121245.1 148794 D 418136 CDS YP_001121246.1 134301278 4958742 149700..151076 1 NC_009257.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 151076 atpD 4958742 atpD Francisella tularensis subsp. tularensis WY96-3418 F0F1 ATP synthase subunit beta YP_001121246.1 149700 D 418136 CDS YP_001121247.1 134301279 4959024 151089..151526 1 NC_009257.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon 151526 atpC 4959024 atpC Francisella tularensis subsp. tularensis WY96-3418 F0F1 ATP synthase subunit epsilon YP_001121247.1 151089 D 418136 CDS YP_001121248.1 134301280 4959028 151737..154580 1 NC_009257.1 hypothetical protein 154580 4959028 FTW_0142 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121248.1 151737 D 418136 CDS YP_001121249.1 134301281 4958932 complement(154597..154926) 1 NC_009257.1 glutaredoxin-like protein 154926 4958932 FTW_0143 Francisella tularensis subsp. tularensis WY96-3418 glutaredoxin-like protein YP_001121249.1 154597 R 418136 CDS YP_001121250.1 134301282 4958846 155062..155640 1 NC_009257.1 superoxide dismutase 155640 sodB 4958846 sodB Francisella tularensis subsp. tularensis WY96-3418 superoxide dismutase YP_001121250.1 155062 D 418136 CDS YP_001121251.1 134301283 4958966 complement(155648..155833) 1 NC_009257.1 hypothetical protein 155833 4958966 FTW_0145 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121251.1 155648 R 418136 CDS YP_001121252.1 134301284 4959150 complement(155845..157110) 1 NC_009257.1 major facilitator superfamily transporter 157110 4959150 FTW_0146 Francisella tularensis subsp. tularensis WY96-3418 major facilitator superfamily transporter YP_001121252.1 155845 R 418136 CDS YP_001121253.1 134301285 4960234 complement(157199..158464) 1 NC_009257.1 citrate synthase I 158464 gltA 4960234 gltA Francisella tularensis subsp. tularensis WY96-3418 citrate synthase I YP_001121253.1 157199 R 418136 CDS YP_001121254.1 134301286 4958918 158809..159189 1 NC_009257.1 succinate dehydrogenase, cytochrome b subunit 159189 sdhC 4958918 sdhC Francisella tularensis subsp. tularensis WY96-3418 succinate dehydrogenase, cytochrome b subunit YP_001121254.1 158809 D 418136 CDS YP_001121255.1 134301287 4958856 159180..159533 1 NC_009257.1 succinate dehydrogenase, hydrophobic membrane anchor protein 159533 sdhD 4958856 sdhD Francisella tularensis subsp. tularensis WY96-3418 succinate dehydrogenase, hydrophobic membrane anchor protein YP_001121255.1 159180 D 418136 CDS YP_001121256.1 134301288 4959449 159546..161339 1 NC_009257.1 succinate dehydrogenase, flavoprotein subunit 161339 sdhA 4959449 sdhA Francisella tularensis subsp. tularensis WY96-3418 succinate dehydrogenase, flavoprotein subunit YP_001121256.1 159546 D 418136 CDS YP_001121257.1 134301289 4959455 161357..162058 1 NC_009257.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 162058 sdhB 4959455 sdhB Francisella tularensis subsp. tularensis WY96-3418 succinate dehydrogenase iron-sulfur subunit YP_001121257.1 161357 D 418136 CDS YP_001121258.1 134301290 4960273 162076..164901 1 NC_009257.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 164901 sucA 4960273 sucA Francisella tularensis subsp. tularensis WY96-3418 2-oxoglutarate dehydrogenase E1 component YP_001121258.1 162076 D 418136 CDS YP_001121259.1 134301291 4960284 164927..166396 1 NC_009257.1 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 166396 sucB 4960284 sucB Francisella tularensis subsp. tularensis WY96-3418 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase YP_001121259.1 164927 D 418136 CDS YP_001121260.1 134301292 4960327 166436..166963 1 NC_009257.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 166963 apt 4960327 apt Francisella tularensis subsp. tularensis WY96-3418 adenine phosphoribosyltransferase YP_001121260.1 166436 D 418136 CDS YP_001121261.1 134301293 4960365 166974..168305 1 NC_009257.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 168305 glmM 4960365 glmM Francisella tularensis subsp. tularensis WY96-3418 phosphoglucosamine mutase YP_001121261.1 166974 D 418136 CDS YP_001121262.1 134301294 4960386 168323..169069 1 NC_009257.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 169069 tpiA 4960386 tpiA Francisella tularensis subsp. tularensis WY96-3418 triosephosphate isomerase YP_001121262.1 168323 D 418136 CDS YP_001121263.1 134301295 4960392 169057..169410 1 NC_009257.1 preprotein translocase subunit SecG 169410 secG 4960392 secG Francisella tularensis subsp. tularensis WY96-3418 preprotein translocase subunit SecG YP_001121263.1 169057 D 418136 CDS YP_001121264.1 134301296 4959578 169580..170209 1 NC_009257.1 hypothetical protein 170209 4959578 FTW_0158 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121264.1 169580 D 418136 CDS YP_001121265.1 134301297 4960358 170263..170535 1 NC_009257.1 hypothetical protein 170535 4960358 FTW_0159 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121265.1 170263 D 418136 CDS YP_001121266.1 134301298 4960145 170642..171094 1 NC_009257.1 hypothetical protein 171094 4960145 FTW_0160 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121266.1 170642 D 418136 CDS YP_001121267.1 134301299 4960026 complement(171091..172233) 1 NC_009257.1 putative oxygen-independent coproporphyrinogen III oxidase 172233 4960026 FTW_0161 Francisella tularensis subsp. tularensis WY96-3418 putative oxygen-independent coproporphyrinogen III oxidase YP_001121267.1 171091 R 418136 CDS YP_001121268.1 134301300 4959813 complement(172238..172615) 1 NC_009257.1 hypothetical protein 172615 4959813 FTW_0162 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121268.1 172238 R 418136 CDS YP_001121269.1 134301301 4959767 172685..173563 1 NC_009257.1 hypothetical protein 173563 4959767 FTW_0163 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121269.1 172685 D 418136 CDS YP_001121270.1 134301302 4959655 173668..176481 1 NC_009257.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 176481 acnA 4959655 acnA Francisella tularensis subsp. tularensis WY96-3418 aconitate hydratase YP_001121270.1 173668 D 418136 CDS YP_001121271.1 134301303 4959473 176576..177604 1 NC_009257.1 pilus retraction ATP ase protein 177604 pilT 4959473 pilT Francisella tularensis subsp. tularensis WY96-3418 pilus retraction ATP ase protein YP_001121271.1 176576 D 418136 CDS YP_001121272.1 134301304 4959220 complement(178667..179113) 1 NC_009257.1 hypothetical protein 179113 4959220 FTW_0169 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121272.1 178667 R 418136 CDS YP_001121273.1 134301305 4958739 181701..182582 1 NC_009257.1 hypothetical protein 182582 4958739 FTW_0174 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121273.1 181701 D 418136 CDS YP_001121274.1 134301306 4959333 complement(182579..184006) 1 NC_009257.1 putative sensor histidine kinase 184006 4959333 FTW_0175 Francisella tularensis subsp. tularensis WY96-3418 putative sensor histidine kinase YP_001121274.1 182579 R 418136 CDS YP_001121275.1 134301307 4959404 184122..185078 1 NC_009257.1 hypothetical protein 185078 4959404 FTW_0176 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121275.1 184122 D 418136 CDS YP_001121276.1 134301308 4959347 185082..185318 1 NC_009257.1 hypothetical protein 185318 4959347 FTW_0177 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121276.1 185082 D 418136 CDS YP_001121277.1 134301309 4959045 185321..186097 1 NC_009257.1 hypothetical protein 186097 4959045 FTW_0178 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121277.1 185321 D 418136 CDS YP_001121278.1 134301310 4959269 186231..186776 1 NC_009257.1 hypothetical protein 186776 4959269 FTW_0179 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121278.1 186231 D 418136 CDS YP_001121279.1 134301311 4959451 complement(join(186754..187305,187305..187634)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 187634 4959451 FTW_0180 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121279.1 186754 R 418136 CDS YP_001121280.1 134301312 4959188 189148..190161 1 NC_009257.1 putative LD carboxypeptidase 190161 4959188 FTW_0185 Francisella tularensis subsp. tularensis WY96-3418 putative LD carboxypeptidase YP_001121280.1 189148 D 418136 CDS YP_001121281.1 134301313 4959770 191341..191469 1 NC_009257.1 hypothetical protein 191469 4959770 FTW_0187 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121281.1 191341 D 418136 CDS YP_001121282.1 134301314 4959527 complement(191606..192187) 1 NC_009257.1 hypothetical protein 192187 4959527 FTW_0188 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121282.1 191606 R 418136 CDS YP_001121283.1 134301315 4959532 complement(192432..193712) 1 NC_009257.1 major facilitator transporter 193712 4959532 FTW_0189 Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001121283.1 192432 R 418136 CDS YP_001121284.1 134301316 4959576 complement(193844..196957) 1 NC_009257.1 RND efflux transporter 196957 4959576 FTW_0190 Francisella tularensis subsp. tularensis WY96-3418 RND efflux transporter YP_001121284.1 193844 R 418136 CDS YP_001121285.1 134301317 4960448 complement(196957..198330) 1 NC_009257.1 RND family membrane fusion protein 198330 4960448 FTW_0191 Francisella tularensis subsp. tularensis WY96-3418 RND family membrane fusion protein YP_001121285.1 196957 R 418136 CDS YP_001121286.1 134301318 4959603 complement(198343..198834) 1 NC_009257.1 disulfide bond formation protein 198834 dsbB 4959603 dsbB Francisella tularensis subsp. tularensis WY96-3418 disulfide bond formation protein YP_001121286.1 198343 R 418136 CDS YP_001121287.1 134301319 4959626 complement(198874..199956) 1 NC_009257.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 199956 4959626 FTW_0193 Francisella tularensis subsp. tularensis WY96-3418 tRNA CCA-pyrophosphorylase YP_001121287.1 198874 R 418136 CDS YP_001121288.1 134301320 4959662 200061..201890 1 NC_009257.1 lipid A transport protein, ABC type transporter, ATP-binding and permease 201890 msbA 4959662 msbA Francisella tularensis subsp. tularensis WY96-3418 lipid A transport protein, ABC type transporter, ATP-binding and permease YP_001121288.1 200061 D 418136 CDS YP_001121289.1 134301321 4959643 201896..202864 1 NC_009257.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 202864 lpxK 4959643 lpxK Francisella tularensis subsp. tularensis WY96-3418 tetraacyldisaccharide 4'-kinase YP_001121289.1 201896 D 418136 CDS YP_001121290.1 134301322 4959676 202960..205653 1 NC_009257.1 DNA polymerase I 205653 polA 4959676 polA Francisella tularensis subsp. tularensis WY96-3418 DNA polymerase I YP_001121290.1 202960 D 418136 CDS YP_001121291.1 134301323 4959686 205673..206449 1 NC_009257.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 206449 4959686 FTW_0197 Francisella tularensis subsp. tularensis WY96-3418 pantothenate kinase YP_001121291.1 205673 D 418136 CDS YP_001121292.1 134301324 4959687 206454..207698 1 NC_009257.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 207698 deoB 4959687 deoB Francisella tularensis subsp. tularensis WY96-3418 phosphopentomutase YP_001121292.1 206454 D 418136 CDS YP_001121293.1 134301325 4959690 207688..208422 1 NC_009257.1 deoxyribose-phosphate aldolase 208422 deoC 4959690 deoC Francisella tularensis subsp. tularensis WY96-3418 deoxyribose-phosphate aldolase YP_001121293.1 207688 D 418136 CDS YP_001121294.1 134301326 4959714 208412..209611 1 NC_009257.1 nucleoside permease, NupC family protein 209611 4959714 FTW_0200 Francisella tularensis subsp. tularensis WY96-3418 nucleoside permease, NupC family protein YP_001121294.1 208412 D 418136 CDS YP_001121295.1 134301327 4959659 209630..210832 1 NC_009257.1 nucleoside permease, NupC family protein 210832 4959659 FTW_0201 Francisella tularensis subsp. tularensis WY96-3418 nucleoside permease, NupC family protein YP_001121295.1 209630 D 418136 CDS YP_001121296.1 134301328 4959779 210845..211474 1 NC_009257.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 211474 tmk 4959779 tmk Francisella tularensis subsp. tularensis WY96-3418 thymidylate kinase YP_001121296.1 210845 D 418136 CDS YP_001121297.1 134301329 4959713 211536..213113 1 NC_009257.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 213113 prfC 4959713 prfC Francisella tularensis subsp. tularensis WY96-3418 peptide chain release factor 3 YP_001121297.1 211536 D 418136 CDS YP_001121298.1 134301330 4958866 213188..214504 1 NC_009257.1 LysM domain-containing protein 214504 4958866 FTW_0204 Francisella tularensis subsp. tularensis WY96-3418 LysM domain-containing protein YP_001121298.1 213188 D 418136 CDS YP_001121299.1 134301331 4958936 214537..215532 1 NC_009257.1 signal recognition particle-docking protein FtsY 215532 ftsY 4958936 ftsY Francisella tularensis subsp. tularensis WY96-3418 signal recognition particle-docking protein FtsY YP_001121299.1 214537 D 418136 CDS YP_001121300.1 134301332 4959342 215623..217845 1 NC_009257.1 DNA helicase II 217845 uvrD 4959342 uvrD Francisella tularensis subsp. tularensis WY96-3418 DNA helicase II YP_001121300.1 215623 D 418136 CDS YP_001121301.1 134301333 4959146 217987..219444 1 NC_009257.1 putative oligopeptide permease, ABC transporter 219444 4959146 FTW_0207 Francisella tularensis subsp. tularensis WY96-3418 putative oligopeptide permease, ABC transporter YP_001121301.1 217987 D 418136 CDS YP_001121302.1 134301334 4959263 221083..222051 1 NC_009257.1 oligopeptide ABC transporter ATP-binding protein 222051 oppD 4959263 oppD Francisella tularensis subsp. tularensis WY96-3418 oligopeptide ABC transporter ATP-binding protein YP_001121302.1 221083 D 418136 CDS YP_001121303.1 134301335 4959808 complement(223031..224233) 1 NC_009257.1 major facilitator transporter 224233 4959808 FTW_0215 Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001121303.1 223031 R 418136 CDS YP_001121304.1 134301336 4959809 224367..224948 1 NC_009257.1 hypothetical protein 224948 4959809 FTW_0216 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121304.1 224367 D 418136 CDS YP_001121305.1 134301337 4959828 complement(224998..225123) 1 NC_009257.1 hypothetical protein 225123 4959828 FTW_0217 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121305.1 224998 R 418136 CDS YP_001121306.1 134301338 4959461 225137..226360 1 NC_009257.1 major facilitator transporter 226360 4959461 FTW_0218 Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001121306.1 225137 D 418136 CDS YP_001121307.1 134301339 4959161 226417..227925 1 NC_009257.1 glycerol kinase 227925 glpK 4959161 glpK Francisella tularensis subsp. tularensis WY96-3418 glycerol kinase YP_001121307.1 226417 D 418136 CDS YP_001121308.1 134301340 4959195 complement(join(227922..228473,228473..228802)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 228802 4959195 FTW_0220 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121308.1 227922 R 418136 CDS YP_001121309.1 134301341 4958969 229118..230650 1 NC_009257.1 FAD -dependent oxidoreductase 230650 4958969 FTW_0222 Francisella tularensis subsp. tularensis WY96-3418 FAD -dependent oxidoreductase YP_001121309.1 229118 D 418136 CDS YP_001121310.1 134301342 4959172 230660..231424 1 NC_009257.1 major intrinsic protein family permease 231424 4959172 FTW_0223 Francisella tularensis subsp. tularensis WY96-3418 major intrinsic protein family permease YP_001121310.1 230660 D 418136 CDS YP_001121311.1 134301343 4958964 231428..232141 1 NC_009257.1 hypothetical protein 232141 4958964 FTW_0224 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121311.1 231428 D 418136 CDS YP_001121312.1 134301344 4958991 232119..232616 1 NC_009257.1 hypothetical protein 232616 4958991 FTW_0225 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121312.1 232119 D 418136 CDS YP_001121313.1 134301345 4958984 232616..234031 1 NC_009257.1 putative ATP-dependent exoDNAse 234031 4958984 FTW_0226 Francisella tularensis subsp. tularensis WY96-3418 putative ATP-dependent exoDNAse YP_001121313.1 232616 D 418136 CDS YP_001121314.1 134301346 4959723 234496..235680 1 NC_009257.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 235680 tufA 4959723 tufA Francisella tularensis subsp. tularensis WY96-3418 elongation factor Tu YP_001121314.1 234496 D 418136 CDS YP_001121315.2 162329653 4959669 235872..236342 1 NC_009257.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 236342 secE 4959669 secE Francisella tularensis subsp. tularensis WY96-3418 preprotein translocase subunit SecE YP_001121315.2 235872 D 418136 CDS YP_001121316.1 134301348 4959167 236358..236891 1 NC_009257.1 transcription termination factor NusG 236891 nusG 4959167 nusG Francisella tularensis subsp. tularensis WY96-3418 transcription termination factor NusG YP_001121316.1 236358 D 418136 CDS YP_001121317.1 134301349 4959155 236960..237394 1 NC_009257.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 237394 rplK 4959155 rplK Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L11 YP_001121317.1 236960 D 418136 CDS YP_001121318.1 134301350 4958972 237397..238092 1 NC_009257.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 238092 rplA 4958972 rplA Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L1 YP_001121318.1 237397 D 418136 CDS YP_001121319.1 134301351 4959855 238262..238780 1 NC_009257.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 238780 rplJ 4959855 rplJ Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L10 YP_001121319.1 238262 D 418136 CDS YP_001121320.1 134301352 4958835 238843..239220 1 NC_009257.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 239220 rplL 4958835 rplL Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L7/L12 YP_001121320.1 238843 D 418136 CDS YP_001121321.1 134301353 4958940 239374..243450 1 NC_009257.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 243450 rpoB 4958940 rpoB Francisella tularensis subsp. tularensis WY96-3418 DNA-directed RNA polymerase subunit beta YP_001121321.1 239374 D 418136 CDS YP_001121322.1 134301354 4959401 243512..247765 1 NC_009257.1 DNA-directed RNA polymerase subunit beta' 247765 rpoC 4959401 rpoC Francisella tularensis subsp. tularensis WY96-3418 DNA-directed RNA polymerase subunit beta' YP_001121322.1 243512 D 418136 CDS YP_001121323.1 134301355 4959870 247868..248104 1 NC_009257.1 hypothetical protein 248104 4959870 FTW_0236 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121323.1 247868 D 418136 CDS YP_001121324.1 134301356 4959872 248104..249114 1 NC_009257.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 249114 4959872 FTW_0237 Francisella tularensis subsp. tularensis WY96-3418 putative DNA-binding/iron metalloprotein/AP endonuclease YP_001121324.1 248104 D 418136 CDS YP_001121325.1 134301357 4959871 249228..250394 1 NC_009257.1 fatty acid desaturase 250394 4959871 FTW_0238 Francisella tularensis subsp. tularensis WY96-3418 fatty acid desaturase YP_001121325.1 249228 D 418136 CDS YP_001121326.1 134301358 4959419 complement(250606..251766) 1 NC_009257.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 251766 metK 4959419 metK Francisella tularensis subsp. tularensis WY96-3418 S-adenosylmethionine synthetase YP_001121326.1 250606 R 418136 CDS YP_001121327.1 134301359 4958890 252060..252308 1 NC_009257.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 252308 rpsP 4958890 rpsP Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S16 YP_001121327.1 252060 D 418136 CDS YP_001121328.1 134301360 4959012 252351..252860 1 NC_009257.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 252860 rimM 4959012 rimM Francisella tularensis subsp. tularensis WY96-3418 16S rRNA-processing protein RimM YP_001121328.1 252351 D 418136 CDS YP_001121329.1 134301361 4959367 253263..254021 1 NC_009257.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 254021 trmD 4959367 trmD Francisella tularensis subsp. tularensis WY96-3418 tRNA (guanine-N(1)-)-methyltransferase YP_001121329.1 253263 D 418136 CDS YP_001121330.1 134301362 4958841 254021..254368 1 NC_009257.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 254368 rplS 4958841 rplS Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L19 YP_001121330.1 254021 D 418136 CDS YP_001121331.1 134301363 4958783 254534..255412 1 NC_009257.1 tyrosine recombinase XerD 255412 xerD 4958783 xerD Francisella tularensis subsp. tularensis WY96-3418 tyrosine recombinase XerD YP_001121331.1 254534 D 418136 CDS YP_001121332.1 134301364 4958837 255535..256380 1 NC_009257.1 oxidoreductase, iron/ascorbate family protein 256380 4958837 FTW_0245 Francisella tularensis subsp. tularensis WY96-3418 oxidoreductase, iron/ascorbate family protein YP_001121332.1 255535 D 418136 CDS YP_001121333.1 134301365 4958726 256385..256969 1 NC_009257.1 acid phosphatase 256969 4958726 FTW_0246 Francisella tularensis subsp. tularensis WY96-3418 acid phosphatase YP_001121333.1 256385 D 418136 CDS YP_001121334.1 134301366 4959178 complement(256966..257850) 1 NC_009257.1 licB-like transmembrane protein 257850 4959178 FTW_0247 Francisella tularensis subsp. tularensis WY96-3418 licB-like transmembrane protein YP_001121334.1 256966 R 418136 CDS YP_001121335.1 134301367 4959338 259652..260119 1 NC_009257.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 260119 4959338 FTW_0251 Francisella tularensis subsp. tularensis WY96-3418 dinucleoside polyphosphate hydrolase YP_001121335.1 259652 D 418136 CDS YP_001121336.1 134301368 4959475 complement(260129..260755) 1 NC_009257.1 PAP2 family protein 260755 4959475 FTW_0252 Francisella tularensis subsp. tularensis WY96-3418 PAP2 family protein YP_001121336.1 260129 R 418136 CDS YP_001121337.1 134301369 4959216 260829..261353 1 NC_009257.1 N-acetyl-anhydromuranmyl-L-alanine amidase 261353 ampD 4959216 ampD Francisella tularensis subsp. tularensis WY96-3418 N-acetyl-anhydromuranmyl-L-alanine amidase YP_001121337.1 260829 D 418136 CDS YP_001121338.1 134301370 4959480 complement(261401..263284) 1 NC_009257.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 263284 parE 4959480 parE Francisella tularensis subsp. tularensis WY96-3418 DNA topoisomerase IV subunit B YP_001121338.1 261401 R 418136 CDS YP_001121339.1 134301371 4959922 complement(263374..264555) 1 NC_009257.1 Bcr/CflA subfamily drug resistance transporter 264555 4959922 FTW_0255 Francisella tularensis subsp. tularensis WY96-3418 Bcr/CflA subfamily drug resistance transporter YP_001121339.1 263374 R 418136 CDS YP_001121340.1 134301372 4959372 complement(264555..265925) 1 NC_009257.1 lipoprotein 265925 4959372 FTW_0256 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001121340.1 264555 R 418136 CDS YP_001121341.1 134301373 4959926 complement(265928..266566) 1 NC_009257.1 hypothetical protein 266566 4959926 FTW_0257 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121341.1 265928 R 418136 CDS YP_001121342.1 134301374 4959465 266746..267990 1 NC_009257.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 267990 hemA 4959465 hemA Francisella tularensis subsp. tularensis WY96-3418 glutamyl-tRNA reductase YP_001121342.1 266746 D 418136 CDS YP_001121343.1 134301375 4959203 267991..269076 1 NC_009257.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 269076 prfA 4959203 prfA Francisella tularensis subsp. tularensis WY96-3418 peptide chain release factor 1 YP_001121343.1 267991 D 418136 CDS YP_001121344.1 134301376 4959129 269069..269923 1 NC_009257.1 HemK family methyltransferase 269923 hemK 4959129 hemK Francisella tularensis subsp. tularensis WY96-3418 HemK family methyltransferase YP_001121344.1 269069 D 418136 CDS YP_001121345.1 134301377 4959086 join(270407..270736,270736..271287) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 271287 4959086 FTW_0262 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121345.1 270407 D 418136 CDS YP_001121346.1 134301378 4959037 complement(271407..273041) 1 NC_009257.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 273041 groEL 4959037 groEL Francisella tularensis subsp. tularensis WY96-3418 chaperonin GroEL YP_001121346.1 271407 R 418136 CDS YP_001121347.1 134301379 4958981 complement(273079..273366) 1 NC_009257.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 273366 groES 4958981 groES Francisella tularensis subsp. tularensis WY96-3418 co-chaperonin GroES YP_001121347.1 273079 R 418136 CDS YP_001121348.1 134301380 4959162 273617..274051 1 NC_009257.1 hypothetical protein 274051 4959162 FTW_0266 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121348.1 273617 D 418136 CDS YP_001121349.1 134301381 4959264 274692..275456 1 NC_009257.1 hypothetical protein 275456 4959264 FTW_0267 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121349.1 274692 D 418136 CDS YP_001121350.1 134301382 4959374 complement(join(275503..276054,276054..276383)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 276383 4959374 FTW_0268 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121350.1 275503 R 418136 CDS YP_001121351.1 134301383 4959692 277908..278027 1 NC_009257.1 hypothetical protein 278027 4959692 FTW_0272 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121351.1 277908 D 418136 CDS YP_001121352.1 134301384 4959938 278047..278748 1 NC_009257.1 putative activator of osmoprotectant transporter 278748 4959938 FTW_0273 Francisella tularensis subsp. tularensis WY96-3418 putative activator of osmoprotectant transporter YP_001121352.1 278047 D 418136 CDS YP_001121353.1 134301385 4959403 278771..279316 1 NC_009257.1 hypothetical protein 279316 4959403 FTW_0274 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121353.1 278771 D 418136 CDS YP_001121354.1 134301386 4959056 complement(279331..280785) 1 NC_009257.1 cation efflux transporter 280785 4959056 FTW_0275 Francisella tularensis subsp. tularensis WY96-3418 cation efflux transporter YP_001121354.1 279331 R 418136 CDS YP_001121355.1 134301387 4959358 281349..281480 1 NC_009257.1 hypothetical protein 281480 4959358 FTW_0277 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121355.1 281349 D 418136 CDS YP_001121356.1 134301388 4959144 complement(281497..282114) 1 NC_009257.1 lipoprotein releasing system subunit A, outer membrane lipoproteins carrier 282114 lolA 4959144 lolA Francisella tularensis subsp. tularensis WY96-3418 lipoprotein releasing system subunit A, outer membrane lipoproteins carrier YP_001121356.1 281497 R 418136 CDS YP_001121357.1 134301389 4959482 complement(282115..284616) 1 NC_009257.1 cell division protein 284616 4959482 FTW_0279 Francisella tularensis subsp. tularensis WY96-3418 cell division protein YP_001121357.1 282115 R 418136 CDS YP_001121358.1 134301390 4959134 284738..285406 1 NC_009257.1 putative membrane associated lipid phosphatase 285406 4959134 FTW_0280 Francisella tularensis subsp. tularensis WY96-3418 putative membrane associated lipid phosphatase YP_001121358.1 284738 D 418136 CDS YP_001121359.1 134301391 4959179 285653..287107 1 NC_009257.1 amino acid transporter 287107 4959179 FTW_0281 Francisella tularensis subsp. tularensis WY96-3418 amino acid transporter YP_001121359.1 285653 D 418136 CDS YP_001121360.1 134301392 4959504 287116..287754 1 NC_009257.1 hypothetical protein 287754 4959504 FTW_0282 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121360.1 287116 D 418136 CDS YP_001121361.1 134301393 4959321 287774..288760 1 NC_009257.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 288760 glpX 4959321 glpX Francisella tularensis subsp. tularensis WY96-3418 fructose 1,6-bisphosphatase II YP_001121361.1 287774 D 418136 CDS YP_001121362.1 134301394 4959043 289067..290533 1 NC_009257.1 sodium/proline symporter 290533 putP 4959043 putP Francisella tularensis subsp. tularensis WY96-3418 sodium/proline symporter YP_001121362.1 289067 D 418136 CDS YP_001121363.1 134301395 4959137 290604..292283 1 NC_009257.1 glycosyltransferase, group 2 family protein 292283 4959137 FTW_0285 Francisella tularensis subsp. tularensis WY96-3418 glycosyltransferase, group 2 family protein YP_001121363.1 290604 D 418136 CDS YP_001121364.1 134301396 4959184 292294..293601 1 NC_009257.1 hypothetical protein 293601 4959184 FTW_0286 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121364.1 292294 D 418136 CDS YP_001121365.1 134301397 4959088 293672..294019 1 NC_009257.1 hypothetical protein 294019 4959088 FTW_0287 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121365.1 293672 D 418136 CDS YP_001121366.1 134301398 4958869 294003..294923 1 NC_009257.1 prepilin-type N-terminal cleavage/methylation domain-containing protein 294923 4958869 FTW_0288 Francisella tularensis subsp. tularensis WY96-3418 prepilin-type N-terminal cleavage/methylation domain-containing protein YP_001121366.1 294003 D 418136 CDS YP_001121367.1 134301399 4959164 294929..296326 1 NC_009257.1 hypothetical protein 296326 4959164 FTW_0289 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121367.1 294929 D 418136 CDS YP_001121368.1 134301400 4959468 296337..296957 1 NC_009257.1 hypothetical protein 296957 4959468 FTW_0290 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121368.1 296337 D 418136 CDS YP_001121369.1 134301401 4959500 297392..297712 1 NC_009257.1 hypothetical protein 297712 4959500 FTW_0292 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121369.1 297392 D 418136 CDS YP_001121370.1 134301402 4959495 297731..298651 1 NC_009257.1 hypothetical protein 298651 4959495 FTW_0293 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121370.1 297731 D 418136 CDS YP_001121371.1 134301403 4959434 complement(join(299828..300379,300379..300708)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 300708 4959434 FTW_0295 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121371.1 299828 R 418136 CDS YP_001121372.1 134301404 4959079 complement(300838..301329) 1 NC_009257.1 acetyltransferase 301329 4959079 FTW_0297 Francisella tularensis subsp. tularensis WY96-3418 acetyltransferase YP_001121372.1 300838 R 418136 CDS YP_001121373.1 134301405 4959975 complement(302591..303535) 1 NC_009257.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 303535 4959975 FTW_0300 Francisella tularensis subsp. tularensis WY96-3418 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_001121373.1 302591 R 418136 CDS YP_001121374.1 134301406 4959992 complement(303539..304933) 1 NC_009257.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 304933 cysS 4959992 cysS Francisella tularensis subsp. tularensis WY96-3418 cysteinyl-tRNA synthetase YP_001121374.1 303539 R 418136 CDS YP_001121375.1 134301407 4959994 complement(join(305309..305860,305860..306189)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 306189 4959994 FTW_0303 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121375.1 305309 R 418136 CDS YP_001121376.1 134301408 4959995 306255..306419 1 NC_009257.1 hypothetical protein 306419 4959995 FTW_0305 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121376.1 306255 D 418136 CDS YP_001121377.1 134301409 4959996 complement(306433..306714) 1 NC_009257.1 hypothetical protein 306714 4959996 FTW_0306 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121377.1 306433 R 418136 CDS YP_001121378.1 134301410 4959997 complement(306727..308229) 1 NC_009257.1 putative amino acid transporter 308229 4959997 FTW_0307 Francisella tularensis subsp. tularensis WY96-3418 putative amino acid transporter YP_001121378.1 306727 R 418136 CDS YP_001121379.1 134301411 4959998 complement(308595..309338) 1 NC_009257.1 hypothetical protein 309338 4959998 FTW_0309 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121379.1 308595 R 418136 CDS YP_001121380.1 134301412 4959999 complement(309341..310036) 1 NC_009257.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 310036 ubiG 4959999 ubiG Francisella tularensis subsp. tularensis WY96-3418 3-demethylubiquinone-9 3-methyltransferase YP_001121380.1 309341 R 418136 CDS YP_001121381.1 134301413 4960222 310178..311278 1 NC_009257.1 putative VacJ like lipoprotein 311278 4960222 FTW_0311 Francisella tularensis subsp. tularensis WY96-3418 putative VacJ like lipoprotein YP_001121381.1 310178 D 418136 CDS YP_001121382.1 134301414 4960148 complement(312393..314681) 1 NC_009257.1 glycosyl hydrolase family protein 314681 4960148 FTW_0313 Francisella tularensis subsp. tularensis WY96-3418 glycosyl hydrolase family protein YP_001121382.1 312393 R 418136 CDS YP_001121383.1 134301415 4958868 315218..316210 1 NC_009257.1 LysR family transcriptional regulator 316210 4958868 FTW_0314 Francisella tularensis subsp. tularensis WY96-3418 LysR family transcriptional regulator YP_001121383.1 315218 D 418136 CDS YP_001121384.1 134301416 4960166 316430..317155 1 NC_009257.1 hypothetical protein 317155 4960166 FTW_0315 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121384.1 316430 D 418136 CDS YP_001121385.1 134301417 4960173 317222..318679 1 NC_009257.1 hypothetical protein 318679 4960173 FTW_0316 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121385.1 317222 D 418136 CDS YP_001121386.1 134301418 4960212 318743..321577 1 NC_009257.1 hypothetical protein 321577 4960212 FTW_0317 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121386.1 318743 D 418136 CDS YP_001121387.1 134301419 4960192 complement(join(321578..322129,322129..322458)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 322458 4960192 FTW_0318 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121387.1 321578 R 418136 CDS YP_001121388.1 134301420 4959579 322452..323372 1 NC_009257.1 hypothetical protein 323372 4959579 FTW_0320 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121388.1 322452 D 418136 CDS YP_001121389.1 134301421 4960088 complement(323652..323888) 1 NC_009257.1 putative BolA like protein 323888 4960088 FTW_0321 Francisella tularensis subsp. tularensis WY96-3418 putative BolA like protein YP_001121389.1 323652 R 418136 CDS YP_001121390.1 134301422 4960170 complement(323905..324198) 1 NC_009257.1 hypothetical protein 324198 4960170 FTW_0322 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121390.1 323905 R 418136 CDS YP_001121391.1 134301423 4960149 complement(324198..324860) 1 NC_009257.1 hypothetical protein 324860 4960149 FTW_0323 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121391.1 324198 R 418136 CDS YP_001121392.1 134301424 4960220 complement(324935..325468) 1 NC_009257.1 hypothetical protein 325468 4960220 FTW_0324 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121392.1 324935 R 418136 CDS YP_001121393.1 134301425 4959349 complement(325468..326232) 1 NC_009257.1 ABC-type transporter involved in resistance to organic solvents, permease 326232 4959349 FTW_0325 Francisella tularensis subsp. tularensis WY96-3418 ABC-type transporter involved in resistance to organic solvents, permease YP_001121393.1 325468 R 418136 CDS YP_001121394.1 134301426 4960177 complement(326236..327039) 1 NC_009257.1 ABC transporter ATP-binding protein 327039 4960177 FTW_0326 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter ATP-binding protein YP_001121394.1 326236 R 418136 CDS YP_001121395.1 134301427 4960172 complement(327053..327325) 1 NC_009257.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 327325 minE 4960172 minE Francisella tularensis subsp. tularensis WY96-3418 cell division topological specificity factor MinE YP_001121395.1 327053 R 418136 CDS YP_001121396.1 134301428 4959958 complement(327328..328152) 1 NC_009257.1 septum site-determining protein MinD 328152 minD 4959958 minD Francisella tularensis subsp. tularensis WY96-3418 septum site-determining protein MinD YP_001121396.1 327328 R 418136 CDS YP_001121397.1 134301429 4959973 complement(328192..328878) 1 NC_009257.1 septum site-determining protein MinC 328878 minC 4959973 minC Francisella tularensis subsp. tularensis WY96-3418 septum site-determining protein MinC YP_001121397.1 328192 R 418136 CDS YP_001121398.1 134301430 4960421 complement(328913..329068) 1 NC_009257.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 329068 rpmG 4960421 rpmG Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L33 YP_001121398.1 328913 R 418136 CDS YP_001121399.1 134301431 4960412 complement(329095..329331) 1 NC_009257.1 required for 70S ribosome assembly; 50S ribosomal protein L28 329331 rpmB 4960412 rpmB Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L28 YP_001121399.1 329095 R 418136 CDS YP_001121400.1 134301432 4960380 complement(329465..329809) 1 NC_009257.1 hypothetical protein 329809 4960380 FTW_0332 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121400.1 329465 R 418136 CDS YP_001121401.1 134301433 4960390 329939..331978 1 NC_009257.1 ATP-dependent DNA helicase RecG 331978 recG 4960390 recG Francisella tularensis subsp. tularensis WY96-3418 ATP-dependent DNA helicase RecG YP_001121401.1 329939 D 418136 CDS YP_001121402.1 134301434 4960279 331982..332179 1 NC_009257.1 hypothetical protein 332179 4960279 FTW_0334 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121402.1 331982 D 418136 CDS YP_001121403.1 134301435 4960253 332733..334247 1 NC_009257.1 fumerate hydratase 334247 fumA 4960253 fumA Francisella tularensis subsp. tularensis WY96-3418 fumerate hydratase YP_001121403.1 332733 D 418136 CDS YP_001121404.1 134301436 4959396 334251..334391 1 NC_009257.1 hypothetical protein 334391 4959396 FTW_0336 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121404.1 334251 D 418136 CDS YP_001121405.1 134301437 4960464 join(334732..335061,335061..335612) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 335612 4960464 FTW_0337 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121405.1 334732 D 418136 CDS YP_001121406.1 134301438 4960261 complement(335590..335991) 1 NC_009257.1 IS1016 family transposase 335991 4960261 FTW_0339 Francisella tularensis subsp. tularensis WY96-3418 IS1016 family transposase YP_001121406.1 335590 R 418136 CDS YP_001121407.1 134301439 4960320 337873..338157 1 NC_009257.1 excinuclease ABC subunit C 338157 4960320 FTW_0344 Francisella tularensis subsp. tularensis WY96-3418 excinuclease ABC subunit C YP_001121407.1 337873 D 418136 CDS YP_001121408.1 134301440 4960349 338226..338756 1 NC_009257.1 hypothetical protein 338756 4960349 FTW_0345 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121408.1 338226 D 418136 CDS YP_001121409.1 134301441 4960408 341865..342527 1 NC_009257.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 342527 ung 4960408 ung Francisella tularensis subsp. tularensis WY96-3418 uracil-DNA glycosylase YP_001121409.1 341865 D 418136 CDS YP_001121410.1 134301442 4960407 complement(342563..343579) 1 NC_009257.1 carbohydrate binding domain-containing protein 343579 4960407 FTW_0349 Francisella tularensis subsp. tularensis WY96-3418 carbohydrate binding domain-containing protein YP_001121410.1 342563 R 418136 CDS YP_001121411.1 134301443 4960413 complement(343684..344229) 1 NC_009257.1 hypothetical protein 344229 4960413 FTW_0350 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121411.1 343684 R 418136 CDS YP_001121412.1 134301444 4960414 344487..347093 1 NC_009257.1 DNA gyrase subunit A 347093 gyrA 4960414 gyrA Francisella tularensis subsp. tularensis WY96-3418 DNA gyrase subunit A YP_001121412.1 344487 D 418136 CDS YP_001121413.1 134301445 4960422 347099..348256 1 NC_009257.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 348256 dxr 4960422 dxr Francisella tularensis subsp. tularensis WY96-3418 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_001121413.1 347099 D 418136 CDS YP_001121414.1 134301446 4960486 348262..350640 1 NC_009257.1 outer membrane protein 350640 4960486 FTW_0353 Francisella tularensis subsp. tularensis WY96-3418 outer membrane protein YP_001121414.1 348262 D 418136 CDS YP_001121415.1 134301447 4960383 350776..351279 1 NC_009257.1 outer membrane protein OmpH 351279 ompH 4960383 ompH Francisella tularensis subsp. tularensis WY96-3418 outer membrane protein OmpH YP_001121415.1 350776 D 418136 CDS YP_001121416.1 134301448 4959595 351298..352311 1 NC_009257.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 352311 lpxD 4959595 lpxD Francisella tularensis subsp. tularensis WY96-3418 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_001121416.1 351298 D 418136 CDS YP_001121417.1 134301449 4959878 352326..352817 1 NC_009257.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 352817 fabZ 4959878 fabZ Francisella tularensis subsp. tularensis WY96-3418 (3R)-hydroxymyristoyl-ACP dehydratase YP_001121417.1 352326 D 418136 CDS YP_001121418.1 134301450 4959722 352820..353599 1 NC_009257.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 353599 lpxA 4959722 lpxA Francisella tularensis subsp. tularensis WY96-3418 UDP-N-acetylglucosamine acyltransferase YP_001121418.1 352820 D 418136 CDS YP_001121419.1 134301451 4959608 353599..354741 1 NC_009257.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 354741 lpxB 4959608 lpxB Francisella tularensis subsp. tularensis WY96-3418 lipid-A-disaccharide synthase YP_001121419.1 353599 D 418136 CDS YP_001121420.1 134301452 4960463 354800..355387 1 NC_009257.1 hypothetical protein 355387 4960463 FTW_0359 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121420.1 354800 D 418136 CDS YP_001121421.1 134301453 4959681 355478..355852 1 NC_009257.1 hypothetical protein 355852 4959681 FTW_0360 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121421.1 355478 D 418136 CDS YP_001121422.1 134301454 4959702 complement(357662..358471) 1 NC_009257.1 hypothetical protein 358471 4959702 FTW_0363 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121422.1 357662 R 418136 CDS YP_001121423.1 134301455 4960112 complement(358541..359305) 1 NC_009257.1 phosphatidylcholine synthase 359305 4960112 FTW_0364 Francisella tularensis subsp. tularensis WY96-3418 phosphatidylcholine synthase YP_001121423.1 358541 R 418136 CDS YP_001121424.1 134301456 4960363 complement(359353..360234) 1 NC_009257.1 polyprenyl synthetase 360234 4960363 FTW_0365 Francisella tularensis subsp. tularensis WY96-3418 polyprenyl synthetase YP_001121424.1 359353 R 418136 CDS YP_001121425.1 134301457 4960113 complement(360231..361526) 1 NC_009257.1 3-deoxy-D-manno-octulosonic-acid transferase 361526 4960113 FTW_0366 Francisella tularensis subsp. tularensis WY96-3418 3-deoxy-D-manno-octulosonic-acid transferase YP_001121425.1 360231 R 418136 CDS YP_001121426.1 134301458 4960243 complement(361631..362209) 1 NC_009257.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 362209 4960243 FTW_0367 Francisella tularensis subsp. tularensis WY96-3418 putative deoxyribonucleotide triphosphate pyrophosphatase YP_001121426.1 361631 R 418136 CDS YP_001121427.1 134301459 4959812 362316..363140 1 NC_009257.1 pyrroline-5-carboxylate reductase 363140 proC 4959812 proC Francisella tularensis subsp. tularensis WY96-3418 pyrroline-5-carboxylate reductase YP_001121427.1 362316 D 418136 CDS YP_001121428.1 134301460 4960074 363377..364468 1 NC_009257.1 hypothetical protein 364468 4960074 FTW_0369 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121428.1 363377 D 418136 CDS YP_001121429.1 134301461 4960132 364899..365585 1 NC_009257.1 two-component response regulator 365585 4960132 FTW_0370 Francisella tularensis subsp. tularensis WY96-3418 two-component response regulator YP_001121429.1 364899 D 418136 CDS YP_001121430.1 134301462 4960459 365590..366453 1 NC_009257.1 signal peptidase I 366453 lepB 4960459 lepB Francisella tularensis subsp. tularensis WY96-3418 signal peptidase I YP_001121430.1 365590 D 418136 CDS YP_001121431.1 134301463 4959616 366460..367152 1 NC_009257.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 367152 rnc 4959616 rnc Francisella tularensis subsp. tularensis WY96-3418 ribonuclease III YP_001121431.1 366460 D 418136 CDS YP_001121432.1 134301464 4960339 367139..368047 1 NC_009257.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 368047 truB 4960339 truB Francisella tularensis subsp. tularensis WY96-3418 tRNA pseudouridine synthase B YP_001121432.1 367139 D 418136 CDS YP_001121433.1 134301465 4960372 368040..370337 1 NC_009257.1 ribonuclease R 370337 rnr 4960372 rnr Francisella tularensis subsp. tularensis WY96-3418 ribonuclease R YP_001121433.1 368040 D 418136 CDS YP_001121434.1 134301466 4960389 complement(370361..371191) 1 NC_009257.1 fatty acid desaturase 371191 4960389 FTW_0375 Francisella tularensis subsp. tularensis WY96-3418 fatty acid desaturase YP_001121434.1 370361 R 418136 CDS YP_001121435.1 134301467 4960409 complement(371205..371948) 1 NC_009257.1 short chain dehydrogenase/reductase family oxidoreductase 371948 4960409 FTW_0376 Francisella tularensis subsp. tularensis WY96-3418 short chain dehydrogenase/reductase family oxidoreductase YP_001121435.1 371205 R 418136 CDS YP_001121436.1 134301468 4960519 complement(371950..372492) 1 NC_009257.1 hypothetical protein 372492 4960519 FTW_0377 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121436.1 371950 R 418136 CDS YP_001121437.1 134301469 4959904 complement(372489..372956) 1 NC_009257.1 hypothetical protein 372956 4959904 FTW_0378 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121437.1 372489 R 418136 CDS YP_001121438.1 134301470 4958798 complement(join(373658..374209,374209..374538)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 374538 4958798 FTW_0380 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121438.1 373658 R 418136 CDS YP_001121439.1 134301471 4959862 complement(376002..377255) 1 NC_009257.1 putative flavin containing amine oxidoreductase 377255 4959862 FTW_0384 Francisella tularensis subsp. tularensis WY96-3418 putative flavin containing amine oxidoreductase YP_001121439.1 376002 R 418136 CDS YP_001121440.1 134301472 4959633 complement(377332..378303) 1 NC_009257.1 two-component system sensor histidine kinase 378303 4959633 FTW_0385 Francisella tularensis subsp. tularensis WY96-3418 two-component system sensor histidine kinase YP_001121440.1 377332 R 418136 CDS YP_001121441.1 134301473 4959834 complement(378353..379042) 1 NC_009257.1 two component response regulator 379042 4959834 FTW_0386 Francisella tularensis subsp. tularensis WY96-3418 two component response regulator YP_001121441.1 378353 R 418136 CDS YP_001121442.1 134301474 4958859 379185..379721 1 NC_009257.1 hypothetical protein 379721 4958859 FTW_0387 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121442.1 379185 D 418136 CDS YP_001121443.1 134301475 4958850 379839..380240 1 NC_009257.1 hypothetical protein 380240 4958850 FTW_0388 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121443.1 379839 D 418136 CDS YP_001121444.1 134301476 4958828 380415..381023 1 NC_009257.1 hypothetical protein 381023 4958828 FTW_0389 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121444.1 380415 D 418136 CDS YP_001121445.1 134301477 4958876 381080..382510 1 NC_009257.1 hypothetical protein 382510 4958876 FTW_0390 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121445.1 381080 D 418136 CDS YP_001121446.1 134301478 4958816 382521..383504 1 NC_009257.1 hypothetical protein 383504 4958816 FTW_0391 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121446.1 382521 D 418136 CDS YP_001121447.1 134301479 4958811 383510..384904 1 NC_009257.1 lipoprotein 384904 4958811 FTW_0392 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001121447.1 383510 D 418136 CDS YP_001121448.1 134301480 4958751 385044..385958 1 NC_009257.1 hypothetical protein 385958 4958751 FTW_0393 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121448.1 385044 D 418136 CDS YP_001121449.1 134301481 4958731 386283..387218 1 NC_009257.1 catalyzes the formation of L-proline from L-ornithine; ornithine cyclodeaminase 387218 4958731 FTW_0394 Francisella tularensis subsp. tularensis WY96-3418 ornithine cyclodeaminase YP_001121449.1 386283 D 418136 CDS YP_001121450.1 134301482 4958716 387289..388704 1 NC_009257.1 putative nicotinate phosphoribosyltransferase 388704 4958716 FTW_0395 Francisella tularensis subsp. tularensis WY96-3418 putative nicotinate phosphoribosyltransferase YP_001121450.1 387289 D 418136 CDS YP_001121451.1 134301483 4958721 388789..389016 1 NC_009257.1 hypothetical protein 389016 4958721 FTW_0396 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121451.1 388789 D 418136 CDS YP_001121452.1 134301484 4958709 complement(390372..390860) 1 NC_009257.1 thioesterase family protein 390860 4958709 FTW_0399 Francisella tularensis subsp. tularensis WY96-3418 thioesterase family protein YP_001121452.1 390372 R 418136 CDS YP_001121453.1 134301485 4958877 complement(390922..392109) 1 NC_009257.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 392109 4958877 FTW_0400 Francisella tularensis subsp. tularensis WY96-3418 acetyl-CoA acetyltransferase YP_001121453.1 390922 R 418136 CDS YP_001121454.1 134301486 4958693 complement(392122..394818) 1 NC_009257.1 fusion product of 3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding protein 394818 4958693 FTW_0401 Francisella tularensis subsp. tularensis WY96-3418 fusion product of 3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding protein YP_001121454.1 392122 R 418136 CDS YP_001121455.1 134301487 4958689 complement(394891..397131) 1 NC_009257.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 397131 fadE 4958689 fadE Francisella tularensis subsp. tularensis WY96-3418 acyl-CoA dehydrogenase YP_001121455.1 394891 R 418136 CDS YP_001121456.1 134301488 4959282 complement(397169..398857) 1 NC_009257.1 putative fatty-acid--CoA ligase 398857 4959282 FTW_0403 Francisella tularensis subsp. tularensis WY96-3418 putative fatty-acid--CoA ligase YP_001121456.1 397169 R 418136 CDS YP_001121457.1 134301489 4958809 399073..399420 1 NC_009257.1 ArsC family arsenate permease 399420 4958809 FTW_0404 Francisella tularensis subsp. tularensis WY96-3418 ArsC family arsenate permease YP_001121457.1 399073 D 418136 CDS YP_001121458.1 134301490 4958696 399469..401685 1 NC_009257.1 isocitrate dehydrogenase 401685 icd 4958696 icd Francisella tularensis subsp. tularensis WY96-3418 isocitrate dehydrogenase YP_001121458.1 399469 D 418136 CDS YP_001121459.1 134301491 4959205 401699..402586 1 NC_009257.1 hypothetical protein 402586 4959205 FTW_0406 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121459.1 401699 D 418136 CDS YP_001121460.1 134301492 4959233 408344..409942 1 NC_009257.1 component of putative O antigen gene cluster; NAD dependent epimerase/dehydratase family protein 409942 wbtA 4959233 wbtA Francisella tularensis subsp. tularensis WY96-3418 NAD dependent epimerase/dehydratase family protein YP_001121460.1 408344 D 418136 CDS YP_001121461.1 134301493 4958970 409935..410567 1 NC_009257.1 component of putative O antigen gene cluster; glycosyltransferase 410567 wbtB 4958970 wbtB Francisella tularensis subsp. tularensis WY96-3418 glycosyltransferase YP_001121461.1 409935 D 418136 CDS YP_001121462.1 134301494 4958949 410569..411360 1 NC_009257.1 component of putative O antigen gen cluster; NAD-dependent epimerase/dehydratase family protein 411360 wbtC 4958949 wbtC Francisella tularensis subsp. tularensis WY96-3418 NAD-dependent epimerase/dehydratase family protein YP_001121462.1 410569 D 418136 CDS YP_001121463.1 134301495 4958695 411350..412441 1 NC_009257.1 component of putative O antigen gene cluster; glycosyltransferase 412441 wbtD 4958695 wbtD Francisella tularensis subsp. tularensis WY96-3418 glycosyltransferase YP_001121463.1 411350 D 418136 CDS YP_001121464.1 134301496 4959313 412459..413769 1 NC_009257.1 component of putative O antigen gene cluster; UDP-glucose/GDP-mannose dehydrogenase 413769 wbtE 4959313 wbtE Francisella tularensis subsp. tularensis WY96-3418 UDP-glucose/GDP-mannose dehydrogenase YP_001121464.1 412459 D 418136 CDS YP_001121465.1 134301497 4958937 413769..414740 1 NC_009257.1 component of putative O antigen gene cluster; NAD-dependent epimerase/dehydratase family protein 414740 wbtF 4958937 wbtF Francisella tularensis subsp. tularensis WY96-3418 NAD-dependent epimerase/dehydratase family protein YP_001121465.1 413769 D 418136 CDS YP_001121466.1 134301498 4958983 414757..415986 1 NC_009257.1 component of putative O antigen gene cluster; O-antigen polymerase 415986 wzy 4958983 wzy Francisella tularensis subsp. tularensis WY96-3418 O-antigen polymerase YP_001121466.1 414757 D 418136 CDS YP_001121467.1 134301499 4959104 415983..417083 1 NC_009257.1 component of putative O antigen gene cluster; glycosyltransferase family protein 417083 wbtG 4959104 wbtG Francisella tularensis subsp. tularensis WY96-3418 glycosyltransferase family protein YP_001121467.1 415983 D 418136 CDS YP_001121468.1 134301500 4959531 417083..418969 1 NC_009257.1 component of putative antigen O gene complex; asparagine synthase 418969 wbtH 4959531 wbtH Francisella tularensis subsp. tularensis WY96-3418 asparagine synthase YP_001121468.1 417083 D 418136 CDS YP_001121469.1 134301501 4959568 418962..420044 1 NC_009257.1 component of putative O antigen gene complex; aminotransferase 420044 wbtI 4959568 wbtI Francisella tularensis subsp. tularensis WY96-3418 aminotransferase YP_001121469.1 418962 D 418136 CDS YP_001121470.1 134301502 4959583 420041..420766 1 NC_009257.1 component of putative O antigen gene complex; hypothetical protein 420766 wbtJ 4959583 wbtJ Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121470.1 420041 D 418136 CDS YP_001121471.1 134301503 4959075 420771..422258 1 NC_009257.1 component of putative O antigen gene complex; O-antigen flippase 422258 wzx 4959075 wzx Francisella tularensis subsp. tularensis WY96-3418 O-antigen flippase YP_001121471.1 420771 D 418136 CDS YP_001121472.1 134301504 4959711 422251..423111 1 NC_009257.1 component of putative O antigen gene complex; glycosyltransferase group 2 family protein 423111 wbtK 4959711 wbtK Francisella tularensis subsp. tularensis WY96-3418 glycosyltransferase group 2 family protein YP_001121472.1 422251 D 418136 CDS YP_001121473.1 134301505 4959706 423136..424020 1 NC_009257.1 component of putative O antigen gene complex; glucose-1-phosphate thymidylyltransferase 424020 wbtL 4959706 wbtL Francisella tularensis subsp. tularensis WY96-3418 glucose-1-phosphate thymidylyltransferase YP_001121473.1 423136 D 418136 CDS YP_001121474.1 134301506 4960452 424132..424326 1 NC_009257.1 hypothetical protein 424326 4960452 FTW_0425 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121474.1 424132 D 418136 CDS YP_001121475.1 134301507 4959775 424583..425584 1 NC_009257.1 dTDP-glucose 4,6-dehydratase 425584 wbtM 4959775 wbtM Francisella tularensis subsp. tularensis WY96-3418 dTDP-glucose 4,6-dehydratase YP_001121475.1 424583 D 418136 CDS YP_001121476.1 134301508 4959877 join(425713..426042,426042..426593) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 426593 4959877 FTW_0427 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121476.1 425713 D 418136 CDS YP_001121477.1 134301509 4959889 complement(426658..427173) 1 NC_009257.1 acetyltransferase 427173 4959889 FTW_0429 Francisella tularensis subsp. tularensis WY96-3418 acetyltransferase YP_001121477.1 426658 R 418136 CDS YP_001121478.1 134301510 4959951 complement(427178..427894) 1 NC_009257.1 hypothetical protein 427894 4959951 FTW_0430 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121478.1 427178 R 418136 CDS YP_001121479.1 134301511 4959952 428665..429300 1 NC_009257.1 amino acid transporter 429300 4959952 FTW_0433 Francisella tularensis subsp. tularensis WY96-3418 amino acid transporter YP_001121479.1 428665 D 418136 CDS YP_001121480.1 134301512 4960037 complement(429297..430187) 1 NC_009257.1 NAD(+)/NADH kinase 430187 4960037 FTW_0434 Francisella tularensis subsp. tularensis WY96-3418 NAD(+)/NADH kinase YP_001121480.1 429297 R 418136 CDS YP_001121481.1 134301513 4960102 430376..431320 1 NC_009257.1 glycosyl transferase family protein 431320 4960102 FTW_0435 Francisella tularensis subsp. tularensis WY96-3418 glycosyl transferase family protein YP_001121481.1 430376 D 418136 CDS YP_001121482.1 134301514 4960080 complement(431324..432103) 1 NC_009257.1 ABC-2 type transporter, membrane protein 432103 4960080 FTW_0436 Francisella tularensis subsp. tularensis WY96-3418 ABC-2 type transporter, membrane protein YP_001121482.1 431324 R 418136 CDS YP_001121483.1 134301515 4960260 complement(432112..433035) 1 NC_009257.1 ABC transporter ATP-binding protein 433035 4960260 FTW_0437 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter ATP-binding protein YP_001121483.1 432112 R 418136 CDS YP_001121484.1 134301516 4960271 complement(433999..434721) 1 NC_009257.1 hypothetical protein 434721 4960271 FTW_0440 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121484.1 433999 R 418136 CDS YP_001121485.1 134301517 4960269 complement(434775..435101) 1 NC_009257.1 hypothetical protein 435101 4960269 FTW_0441 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121485.1 434775 R 418136 CDS YP_001121486.1 134301518 4960309 complement(435227..435994) 1 NC_009257.1 TatD family hydrolase 435994 4960309 FTW_0442 Francisella tularensis subsp. tularensis WY96-3418 TatD family hydrolase YP_001121486.1 435227 R 418136 CDS YP_001121487.1 134301519 4960350 437672..438145 1 NC_009257.1 ferritin-like protein 438145 4960350 FTW_0445 Francisella tularensis subsp. tularensis WY96-3418 ferritin-like protein YP_001121487.1 437672 D 418136 CDS YP_001121488.1 134301520 4959587 complement(438763..439719) 1 NC_009257.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 439719 rpoA1 4959587 rpoA1 Francisella tularensis subsp. tularensis WY96-3418 DNA-directed RNA polymerase subunit alpha YP_001121488.1 438763 R 418136 CDS YP_001121489.1 134301521 4960411 complement(439807..440709) 1 NC_009257.1 recombination factor protein RarA 440709 4960411 FTW_0447 Francisella tularensis subsp. tularensis WY96-3418 recombination factor protein RarA YP_001121489.1 439807 R 418136 CDS YP_001121490.1 134301522 4960375 complement(441135..441251) 1 NC_009257.1 hypothetical protein 441251 4960375 FTW_0448 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121490.1 441135 R 418136 CDS YP_001121491.1 134301523 4960301 complement(441278..442204) 1 NC_009257.1 exopolyphosphatase 442204 4960301 FTW_0449 Francisella tularensis subsp. tularensis WY96-3418 exopolyphosphatase YP_001121491.1 441278 R 418136 CDS YP_001121492.1 134301524 4959987 442402..442725 1 NC_009257.1 thioredoxin 442725 trx1 4959987 trx1 Francisella tularensis subsp. tularensis WY96-3418 thioredoxin YP_001121492.1 442402 D 418136 CDS YP_001121493.1 134301525 4960298 442768..444030 1 NC_009257.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 444030 rho 4960298 rho Francisella tularensis subsp. tularensis WY96-3418 transcription termination factor Rho YP_001121493.1 442768 D 418136 CDS YP_001121494.1 134301526 4959832 complement(445142..446626) 1 NC_009257.1 phosphoglucomutase/phosphomannomutase 446626 4959832 FTW_0452 Francisella tularensis subsp. tularensis WY96-3418 phosphoglucomutase/phosphomannomutase YP_001121494.1 445142 R 418136 CDS YP_001121495.1 134301527 4959389 complement(446657..448063) 1 NC_009257.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 448063 4959389 FTW_0453 Francisella tularensis subsp. tularensis WY96-3418 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_001121495.1 446657 R 418136 CDS YP_001121496.1 134301528 4959783 complement(join(448316..448867,448867..449196)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 449196 4959783 FTW_0454 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121496.1 448316 R 418136 CDS YP_001121497.1 134301529 4959038 449354..449653 1 NC_009257.1 ArsR family transcriptional regulator 449653 4959038 FTW_0456 Francisella tularensis subsp. tularensis WY96-3418 ArsR family transcriptional regulator YP_001121497.1 449354 D 418136 CDS YP_001121498.1 134301530 4959033 449719..450237 1 NC_009257.1 hypothetical protein 450237 4959033 FTW_0457 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121498.1 449719 D 418136 CDS YP_001121499.1 134301531 4958934 451998..452684 1 NC_009257.1 metallo-beta-lactamase family protein 452684 4958934 FTW_0460 Francisella tularensis subsp. tularensis WY96-3418 metallo-beta-lactamase family protein YP_001121499.1 451998 D 418136 CDS YP_001121500.1 134301532 4958678 452686..453435 1 NC_009257.1 hypothetical protein 453435 4958678 FTW_0461 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121500.1 452686 D 418136 CDS YP_001121501.1 134301533 4959523 complement(453428..454036) 1 NC_009257.1 2OG-Fe(II) oxygenase 454036 4959523 FTW_0462 Francisella tularensis subsp. tularensis WY96-3418 2OG-Fe(II) oxygenase YP_001121501.1 453428 R 418136 CDS YP_001121502.1 134301534 4959562 complement(454088..454534) 1 NC_009257.1 hypothetical protein 454534 4959562 FTW_0463 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121502.1 454088 R 418136 CDS YP_001121503.1 134301535 4959601 complement(454756..455223) 1 NC_009257.1 hypothetical protein 455223 4959601 FTW_0464 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121503.1 454756 R 418136 CDS YP_001121504.1 134301536 4959629 complement(455284..455685) 1 NC_009257.1 hypothetical protein 455685 4959629 FTW_0465 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121504.1 455284 R 418136 CDS YP_001121505.1 134301537 4959630 455872..456297 1 NC_009257.1 transcription antitermination factor NusB 456297 nusB 4959630 nusB Francisella tularensis subsp. tularensis WY96-3418 transcription antitermination factor NusB YP_001121505.1 455872 D 418136 CDS YP_001121506.1 134301538 4959639 complement(456281..457051) 1 NC_009257.1 carbon-nitrogen family hydrolase 457051 4959639 FTW_0467 Francisella tularensis subsp. tularensis WY96-3418 carbon-nitrogen family hydrolase YP_001121506.1 456281 R 418136 CDS YP_001121507.1 134301539 4959672 457220..457633 1 NC_009257.1 lipoprotein 457633 4959672 FTW_0468 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001121507.1 457220 D 418136 CDS YP_001121508.1 134301540 4959729 complement(457669..458589) 1 NC_009257.1 hypothetical protein 458589 4959729 FTW_0469 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121508.1 457669 R 418136 CDS YP_001121509.1 134301541 4959731 complement(458697..459179) 1 NC_009257.1 hypothetical protein 459179 4959731 FTW_0470 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121509.1 458697 R 418136 CDS YP_001121510.1 134301542 4959741 complement(459179..460312) 1 NC_009257.1 class I/II aminotransferase 460312 4959741 FTW_0471 Francisella tularensis subsp. tularensis WY96-3418 class I/II aminotransferase YP_001121510.1 459179 R 418136 CDS YP_001121511.1 134301543 4959815 complement(460458..462155) 1 NC_009257.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 462155 proS 4959815 proS Francisella tularensis subsp. tularensis WY96-3418 prolyl-tRNA synthetase YP_001121511.1 460458 R 418136 CDS YP_001121512.1 134301544 4959831 complement(462439..462609) 1 NC_009257.1 hypothetical protein 462609 4959831 FTW_0473 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121512.1 462439 R 418136 CDS YP_001121513.1 134301545 4959836 complement(462761..462958) 1 NC_009257.1 hypothetical protein 462958 4959836 FTW_0474 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121513.1 462761 R 418136 CDS YP_001121514.1 134301546 4959843 complement(463009..463518) 1 NC_009257.1 hypothetical protein 463518 4959843 FTW_0475 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121514.1 463009 R 418136 CDS YP_001121515.1 134301547 4959827 464255..464389 1 NC_009257.1 hypothetical protein 464389 4959827 FTW_0476 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121515.1 464255 D 418136 CDS YP_001121516.1 134301548 4959853 complement(464744..465280) 1 NC_009257.1 hypothetical protein 465280 4959853 FTW_0477 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121516.1 464744 R 418136 CDS YP_001121517.1 134301549 4959858 465358..465477 1 NC_009257.1 hypothetical protein 465477 4959858 FTW_0478 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121517.1 465358 D 418136 CDS YP_001121518.1 134301550 4959590 465987..466403 1 NC_009257.1 putative regulator of cysteine desulfurase activity 466403 4959590 FTW_0479 Francisella tularensis subsp. tularensis WY96-3418 putative regulator of cysteine desulfurase activity YP_001121518.1 465987 D 418136 CDS YP_001121519.1 134301551 4959866 466404..467153 1 NC_009257.1 putative uroporphyrinogen III synthase 467153 4959866 FTW_0480 Francisella tularensis subsp. tularensis WY96-3418 putative uroporphyrinogen III synthase YP_001121519.1 466404 D 418136 CDS YP_001121520.1 134301552 4959875 467119..468204 1 NC_009257.1 hypothetical protein 468204 4959875 FTW_0481 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121520.1 467119 D 418136 CDS YP_001121521.1 134301553 4959884 468201..469358 1 NC_009257.1 hypothetical protein 469358 4959884 FTW_0482 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121521.1 468201 D 418136 CDS YP_001121522.1 134301554 4959885 469372..470130 1 NC_009257.1 hydroxyacylglutathione hydrolase 470130 4959885 FTW_0483 Francisella tularensis subsp. tularensis WY96-3418 hydroxyacylglutathione hydrolase YP_001121522.1 469372 D 418136 CDS YP_001121523.1 134301555 4959942 complement(470208..470915) 1 NC_009257.1 putative cell division protein 470915 4959942 FTW_0484 Francisella tularensis subsp. tularensis WY96-3418 putative cell division protein YP_001121523.1 470208 R 418136 CDS YP_001121524.1 134301556 4959950 471024..471248 1 NC_009257.1 hypothetical protein 471248 4959950 FTW_0485 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121524.1 471024 D 418136 CDS YP_001121525.1 134301557 4959970 471265..472899 1 NC_009257.1 hypothetical protein 472899 4959970 FTW_0486 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121525.1 471265 D 418136 CDS YP_001121526.1 134301558 4959597 complement(473471..474124) 1 NC_009257.1 peptidase S24-like domain-containing protein 474124 4959597 FTW_0487 Francisella tularensis subsp. tularensis WY96-3418 peptidase S24-like domain-containing protein YP_001121526.1 473471 R 418136 CDS YP_001121527.1 134301559 4960019 474293..474679 1 NC_009257.1 hypothetical protein 474679 4960019 FTW_0488 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121527.1 474293 D 418136 CDS YP_001121528.1 134301560 4960035 complement(474767..475450) 1 NC_009257.1 hypothetical protein 475450 4960035 FTW_0489 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121528.1 474767 R 418136 CDS YP_001121529.1 134301561 4960051 475627..477213 1 NC_009257.1 putative glutamate synthase 477213 4960051 FTW_0490 Francisella tularensis subsp. tularensis WY96-3418 putative glutamate synthase YP_001121529.1 475627 D 418136 CDS YP_001121530.1 134301562 4960052 477290..480529 1 NC_009257.1 exodeoxyribonuclease V subunit gamma 480529 recC 4960052 recC Francisella tularensis subsp. tularensis WY96-3418 exodeoxyribonuclease V subunit gamma YP_001121530.1 477290 D 418136 CDS YP_001121531.1 134301563 4960067 480513..481043 1 NC_009257.1 hypothetical protein 481043 4960067 FTW_0492 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121531.1 480513 D 418136 CDS YP_001121532.1 134301564 4960075 481186..482616 1 NC_009257.1 AAA ATPase 482616 4960075 FTW_0493 Francisella tularensis subsp. tularensis WY96-3418 AAA ATPase YP_001121532.1 481186 D 418136 CDS YP_001121533.1 134301565 4959142 482688..486341 1 NC_009257.1 exodeoxyribonuclease V subunit beta 486341 recB 4959142 recB Francisella tularensis subsp. tularensis WY96-3418 exodeoxyribonuclease V subunit beta YP_001121533.1 482688 D 418136 CDS YP_001121534.1 134301566 4960216 486334..488175 1 NC_009257.1 exodeoxyribonuclease V subunit alpha 488175 recD 4960216 recD Francisella tularensis subsp. tularensis WY96-3418 exodeoxyribonuclease V subunit alpha YP_001121534.1 486334 D 418136 CDS YP_001121535.1 134301567 4959857 complement(488184..488954) 1 NC_009257.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 488954 4959857 FTW_0496 Francisella tularensis subsp. tularensis WY96-3418 pantothenate kinase YP_001121535.1 488184 R 418136 CDS YP_001121536.1 134301568 4959320 complement(488958..489293) 1 NC_009257.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 489293 panD 4959320 panD Francisella tularensis subsp. tularensis WY96-3418 aspartate alpha-decarboxylase YP_001121536.1 488958 R 418136 CDS YP_001121537.1 134301569 4959437 complement(489287..490072) 1 NC_009257.1 pantoate--beta-alanine ligase 490072 panC 4959437 panC Francisella tularensis subsp. tularensis WY96-3418 pantoate--beta-alanine ligase YP_001121537.1 489287 R 418136 CDS YP_001121538.1 134301570 4959444 complement(490059..490856) 1 NC_009257.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 490856 panB 4959444 panB Francisella tularensis subsp. tularensis WY96-3418 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_001121538.1 490059 R 418136 CDS YP_001121539.1 134301571 4959237 complement(490858..491574) 1 NC_009257.1 hypothetical protein 491574 4959237 FTW_0500 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121539.1 490858 R 418136 CDS YP_001121540.1 134301572 4959376 491882..493918 1 NC_009257.1 DNA ligase 493918 ligA 4959376 ligA Francisella tularensis subsp. tularensis WY96-3418 DNA ligase YP_001121540.1 491882 D 418136 CDS YP_001121541.1 134301573 4959299 complement(join(494268..494819,494819..495148)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 495148 4959299 FTW_0502 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121541.1 494268 R 418136 CDS YP_001121542.1 134301574 4959567 495142..495408 1 NC_009257.1 hypothetical protein 495408 4959567 FTW_0504 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121542.1 495142 D 418136 CDS YP_001121543.1 134301575 4959526 495501..495992 1 NC_009257.1 hypothetical protein 495992 4959526 FTW_0505 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121543.1 495501 D 418136 CDS YP_001121544.1 134301576 4959585 complement(495970..497250) 1 NC_009257.1 ribosomal RNA small subunit methyltransferase B 497250 sun 4959585 sun Francisella tularensis subsp. tularensis WY96-3418 ribosomal RNA small subunit methyltransferase B YP_001121544.1 495970 R 418136 CDS YP_001121545.1 134301577 4959623 complement(497250..498038) 1 NC_009257.1 inositol monophosphatase family protein 498038 4959623 FTW_0507 Francisella tularensis subsp. tularensis WY96-3418 inositol monophosphatase family protein YP_001121545.1 497250 R 418136 CDS YP_001121546.1 134301578 4959649 complement(498125..499177) 1 NC_009257.1 hypothetical protein 499177 4959649 FTW_0508 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121546.1 498125 R 418136 CDS YP_001121547.1 134301579 4959665 500611..501297 1 NC_009257.1 hypothetical protein 501297 4959665 FTW_0512 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121547.1 500611 D 418136 CDS YP_001121548.1 134301580 4959726 complement(501287..501601) 1 NC_009257.1 YCII-related domain-containing protein 501601 4959726 FTW_0513 Francisella tularensis subsp. tularensis WY96-3418 YCII-related domain-containing protein YP_001121548.1 501287 R 418136 CDS YP_001121549.1 134301581 4959803 complement(501652..502911) 1 NC_009257.1 component of fatty acid biosynthesis gene cluster; beta-ketoacyl-acyl carrier protein synthase II 502911 fabF 4959803 fabF Francisella tularensis subsp. tularensis WY96-3418 beta-ketoacyl-acyl carrier protein synthase II YP_001121549.1 501652 R 418136 CDS YP_001121550.1 134301582 4959820 complement(502991..503275) 1 NC_009257.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 503275 acpP 4959820 acpP Francisella tularensis subsp. tularensis WY96-3418 acyl carrier protein YP_001121550.1 502991 R 418136 CDS YP_001121551.1 134301583 4959829 complement(503371..504114) 1 NC_009257.1 component of fatty acid biosynthesis gene cluster; 3-oxoacyl-(acyl-carrier-protein) reductase 504114 fabG 4959829 fabG Francisella tularensis subsp. tularensis WY96-3418 3-oxoacyl-(acyl-carrier-protein) reductase YP_001121551.1 503371 R 418136 CDS YP_001121552.1 134301584 4959856 complement(504128..505048) 1 NC_009257.1 component of fatty acid biosynthesis gene cluster; malonyl CoA-acyl carrier protein transacylase 505048 fabD 4959856 fabD Francisella tularensis subsp. tularensis WY96-3418 malonyl CoA-acyl carrier protein transacylase YP_001121552.1 504128 R 418136 CDS YP_001121553.1 134301585 4959882 complement(505096..506067) 1 NC_009257.1 component of fatty acid biosynthesis gene cluster; 3-oxoacyl-(acyl-carrier-protein) synthase III 506067 fabH 4959882 fabH Francisella tularensis subsp. tularensis WY96-3418 3-oxoacyl-(acyl-carrier-protein) synthase III YP_001121553.1 505096 R 418136 CDS YP_001121554.1 134301586 4959780 complement(506164..507210) 1 NC_009257.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 507210 plsX 4959780 plsX Francisella tularensis subsp. tularensis WY96-3418 putative glycerol-3-phosphate acyltransferase PlsX YP_001121554.1 506164 R 418136 CDS YP_001121555.1 134301587 4959901 complement(507309..507491) 1 NC_009257.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 507491 rpmF 4959901 rpmF Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L32 YP_001121555.1 507309 R 418136 CDS YP_001121556.1 134301588 4959896 complement(507535..508038) 1 NC_009257.1 hypothetical protein 508038 4959896 FTW_0521 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121556.1 507535 R 418136 CDS YP_001121557.1 134301589 4959943 508178..510169 1 NC_009257.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 510169 tktA 4959943 tktA Francisella tularensis subsp. tularensis WY96-3418 transketolase YP_001121557.1 508178 D 418136 CDS YP_001121558.1 134301590 4959959 510162..511208 1 NC_009257.1 glyceraldehyde-3-phosphate dehydrogenase, type I 511208 gapA 4959959 gapA Francisella tularensis subsp. tularensis WY96-3418 glyceraldehyde-3-phosphate dehydrogenase, type I YP_001121558.1 510162 D 418136 CDS YP_001121559.1 134301591 4960068 511227..512405 1 NC_009257.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 512405 pgk 4960068 pgk Francisella tularensis subsp. tularensis WY96-3418 phosphoglycerate kinase YP_001121559.1 511227 D 418136 CDS YP_001121560.1 134301592 4960120 512421..513857 1 NC_009257.1 pyruvate kinase 513857 pyk 4960120 pyk Francisella tularensis subsp. tularensis WY96-3418 pyruvate kinase YP_001121560.1 512421 D 418136 CDS YP_001121561.1 134301593 4960139 513873..514937 1 NC_009257.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 514937 fba 4960139 fba Francisella tularensis subsp. tularensis WY96-3418 fructose-1,6-bisphosphate aldolase YP_001121561.1 513873 D 418136 CDS YP_001121562.1 134301594 4960227 join(516949..517278,517278..517829) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 517829 4960227 FTW_0530 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121562.1 516949 D 418136 CDS YP_001121563.1 134301595 4958872 518843..519856 1 NC_009257.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 519856 anmK 4958872 anmK Francisella tularensis subsp. tularensis WY96-3418 anhydro-N-acetylmuramic acid kinase YP_001121563.1 518843 D 418136 CDS YP_001121564.1 134301596 4959478 520088..523675 1 NC_009257.1 pathogenicity determinant protein D, pdpD 523675 pdpD2 4959478 pdpD2 Francisella tularensis subsp. tularensis WY96-3418 pathogenicity determinant protein D, pdpD YP_001121564.1 520088 D 418136 CDS YP_001121565.1 134301597 4959466 523756..524310 1 NC_009257.1 intracellular growth locus, iglA 524310 iglA2 4959466 iglA2 Francisella tularensis subsp. tularensis WY96-3418 intracellular growth locus, iglA YP_001121565.1 523756 D 418136 CDS YP_001121566.1 134301598 4959001 524324..525844 1 NC_009257.1 intracellular growth locus iglB 525844 iglB2 4959001 iglB2 Francisella tularensis subsp. tularensis WY96-3418 intracellular growth locus iglB YP_001121566.1 524324 D 418136 CDS YP_001121567.1 134301599 4958773 525855..526490 1 NC_009257.1 intracellular growth locus iglC 526490 iglC2 4958773 iglC2 Francisella tularensis subsp. tularensis WY96-3418 intracellular growth locus iglC YP_001121567.1 525855 D 418136 CDS YP_001121568.1 134301600 4958785 526511..527707 1 NC_009257.1 intracellular growth locus iglD 527707 iglD2 4958785 iglD2 Francisella tularensis subsp. tularensis WY96-3418 intracellular growth locus iglD YP_001121568.1 526511 D 418136 CDS YP_001121569.1 134301601 4959062 complement(527714..528289) 1 NC_009257.1 hypothetical protein 528289 4959062 FTW_0539 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121569.1 527714 R 418136 CDS YP_001121570.1 134301602 4959090 complement(528307..532293) 1 NC_009257.1 pathogenicity determinant protein pdpC2 532293 pdpC2 4959090 pdpC2 Francisella tularensis subsp. tularensis WY96-3418 pathogenicity determinant protein pdpC2 YP_001121570.1 528307 R 418136 CDS YP_001121571.1 134301603 4959163 complement(532333..533049) 1 NC_009257.1 hypothetical protein 533049 4959163 FTW_0541 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121571.1 532333 R 418136 CDS YP_001121572.1 134301604 4959122 complement(533072..534223) 1 NC_009257.1 hypothetical protein 534223 4959122 FTW_0542 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121572.1 533072 R 418136 CDS YP_001121573.1 134301605 4958900 complement(534245..534868) 1 NC_009257.1 hypothetical protein 534868 4958900 FTW_0543 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121573.1 534245 R 418136 CDS YP_001121574.1 134301606 4959402 complement(534881..536311) 1 NC_009257.1 hypothetical protein 536311 4959402 FTW_0544 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121574.1 534881 R 418136 CDS YP_001121575.1 134301607 4959185 complement(536324..536845) 1 NC_009257.1 hypothetical protein 536845 4959185 FTW_0545 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121575.1 536324 R 418136 CDS YP_001121576.1 134301608 4959334 complement(536846..538576) 1 NC_009257.1 hypothetical protein 538576 4959334 FTW_0546 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121576.1 536846 R 418136 CDS YP_001121577.1 134301609 4959391 complement(538581..539075) 1 NC_009257.1 hypothetical protein 539075 4959391 FTW_0547 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121577.1 538581 R 418136 CDS YP_001121578.1 134301610 4959369 complement(539088..539465) 1 NC_009257.1 putative lipoprotein 539465 4959369 FTW_0548 Francisella tularensis subsp. tularensis WY96-3418 putative lipoprotein YP_001121578.1 539088 R 418136 CDS YP_001121579.1 134301611 4959364 complement(539455..542736) 1 NC_009257.1 pathogenicity determinant protein pdpB2 542736 pdpB2 4959364 pdpB2 Francisella tularensis subsp. tularensis WY96-3418 pathogenicity determinant protein pdpB2 YP_001121579.1 539455 R 418136 CDS YP_001121580.1 134301612 4959223 complement(542741..545203) 1 NC_009257.1 pathogenicity determinant protein, pdpA 545203 pdpA2 4959223 pdpA2 Francisella tularensis subsp. tularensis WY96-3418 pathogenicity determinant protein, pdpA YP_001121580.1 542741 R 418136 CDS YP_001121581.1 134301613 4959463 complement(550843..551427) 1 NC_009257.1 hypothetical protein 551427 4959463 FTW_0552 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121581.1 550843 R 418136 CDS YP_001121582.1 134301614 4958939 complement(551674..552597) 1 NC_009257.1 putative cystathionine beta-synthase 552597 4958939 FTW_0553 Francisella tularensis subsp. tularensis WY96-3418 putative cystathionine beta-synthase YP_001121582.1 551674 R 418136 CDS YP_001121583.1 134301615 4959331 complement(553024..553869) 1 NC_009257.1 choloylglycine hydrolase family protein 553869 4959331 FTW_0554 Francisella tularensis subsp. tularensis WY96-3418 choloylglycine hydrolase family protein YP_001121583.1 553024 R 418136 CDS YP_001121584.1 134301616 4959247 554004..554894 1 NC_009257.1 transcriptional regulator, LysR family protein 554894 4959247 FTW_0555 Francisella tularensis subsp. tularensis WY96-3418 transcriptional regulator, LysR family protein YP_001121584.1 554004 D 418136 CDS YP_001121585.1 134301617 4959307 554926..555120 1 NC_009257.1 hypothetical protein 555120 4959307 FTW_0556 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121585.1 554926 D 418136 CDS YP_001121586.1 134301618 4959398 complement(555130..556482) 1 NC_009257.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 556482 trmE 4959398 trmE Francisella tularensis subsp. tularensis WY96-3418 tRNA modification GTPase TrmE YP_001121586.1 555130 R 418136 CDS YP_001121587.1 134301619 4960248 complement(556488..556733) 1 NC_009257.1 hypothetical protein 556733 4960248 FTW_0558 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121587.1 556488 R 418136 CDS YP_001121588.1 134301620 4959061 556852..557148 1 NC_009257.1 ribosomal subunit interface protein 557148 yfiA 4959061 yfiA Francisella tularensis subsp. tularensis WY96-3418 ribosomal subunit interface protein YP_001121588.1 556852 D 418136 CDS YP_001121589.1 134301621 4959227 557185..557640 1 NC_009257.1 PEP-dependent sugar PTS system family protein 557640 4959227 FTW_0560 Francisella tularensis subsp. tularensis WY96-3418 PEP-dependent sugar PTS system family protein YP_001121589.1 557185 D 418136 CDS YP_001121590.1 134301622 4959187 557633..558376 1 NC_009257.1 RNA methyltransferase 558376 4959187 FTW_0561 Francisella tularensis subsp. tularensis WY96-3418 RNA methyltransferase YP_001121590.1 557633 D 418136 CDS YP_001121591.1 134301623 4959035 558378..558941 1 NC_009257.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 558941 rnhB 4959035 rnhB Francisella tularensis subsp. tularensis WY96-3418 ribonuclease HII YP_001121591.1 558378 D 418136 CDS YP_001121592.1 134301624 4960251 558934..560205 1 NC_009257.1 sodium-solute symporter family protein 560205 4960251 FTW_0563 Francisella tularensis subsp. tularensis WY96-3418 sodium-solute symporter family protein YP_001121592.1 558934 D 418136 CDS YP_001121593.1 134301625 4959217 complement(560202..560609) 1 NC_009257.1 inferred from sequence similarity with MglB protein from F. novicida, function derived from mutation phenotype. PMID: 9701818; ClpXP protease specificity-enhancing factor 560609 mglB 4959217 mglB Francisella tularensis subsp. tularensis WY96-3418 ClpXP protease specificity-enhancing factor YP_001121593.1 560202 R 418136 CDS YP_001121594.1 134301626 4958930 complement(560611..561228) 1 NC_009257.1 inferred from sequence similarity with MglB protein from F. novicida, function derived from mutation phenotype. PMID: 9701818; macrophage growth locus subunit A 561228 mglA 4958930 mglA Francisella tularensis subsp. tularensis WY96-3418 macrophage growth locus subunit A YP_001121594.1 560611 R 418136 CDS YP_001121595.1 134301627 4959064 complement(561288..561686) 1 NC_009257.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 561686 rpsI 4959064 rpsI Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S9 YP_001121595.1 561288 R 418136 CDS YP_001121596.1 134301628 4959005 complement(561693..562121) 1 NC_009257.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 562121 rplM 4959005 rplM Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L13 YP_001121596.1 561693 R 418136 CDS YP_001121597.1 134301629 4958962 complement(562260..563444) 1 NC_009257.1 hypothetical protein 563444 4958962 FTW_0568 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121597.1 562260 R 418136 CDS YP_001121598.1 134301630 4959025 complement(563437..564588) 1 NC_009257.1 membrane-bound lytic murein transglycosylase A (MLT) family protein 564588 4959025 FTW_0569 Francisella tularensis subsp. tularensis WY96-3418 membrane-bound lytic murein transglycosylase A (MLT) family protein YP_001121598.1 563437 R 418136 CDS YP_001121599.1 134301631 4959000 564692..565279 1 NC_009257.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 565279 grpE 4959000 grpE Francisella tularensis subsp. tularensis WY96-3418 heat shock protein GrpE YP_001121599.1 564692 D 418136 CDS YP_001121600.1 134301632 4958820 565380..567308 1 NC_009257.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 567308 dnaK 4958820 dnaK Francisella tularensis subsp. tularensis WY96-3418 molecular chaperone DnaK YP_001121600.1 565380 D 418136 CDS YP_001121601.1 134301633 4958978 567397..568512 1 NC_009257.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 568512 dnaJ 4958978 dnaJ Francisella tularensis subsp. tularensis WY96-3418 chaperone protein DnaJ YP_001121601.1 567397 D 418136 CDS YP_001121602.1 134301634 4959115 complement(568526..569422) 1 NC_009257.1 transcriptional regulator, LysR family protein 569422 4959115 FTW_0573 Francisella tularensis subsp. tularensis WY96-3418 transcriptional regulator, LysR family protein YP_001121602.1 568526 R 418136 CDS YP_001121603.1 134301635 4958845 569522..570235 1 NC_009257.1 hypothetical protein 570235 4958845 FTW_0574 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121603.1 569522 D 418136 CDS YP_001121604.1 134301636 4959491 join(570259..570588,570588..571139) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 571139 4959491 FTW_0575 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121604.1 570259 D 418136 CDS YP_001121605.1 134301637 4959472 complement(571319..571564) 1 NC_009257.1 hypothetical protein 571564 4959472 FTW_0577 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121605.1 571319 R 418136 CDS YP_001121606.1 134301638 4960322 complement(571578..572291) 1 NC_009257.1 hypothetical protein 572291 4960322 FTW_0578 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121606.1 571578 R 418136 CDS YP_001121607.1 134301639 4960326 572577..573359 1 NC_009257.1 more than 60% identity to characterized protein from P. aeruginosa PMID: 10464225; enoyl-(acyl-carrier-protein) reductase 573359 fabI 4960326 fabI Francisella tularensis subsp. tularensis WY96-3418 enoyl-(acyl-carrier-protein) reductase YP_001121607.1 572577 D 418136 CDS YP_001121608.1 134301640 4960354 573506..574468 1 NC_009257.1 beta-lactamase superfamily hydrolase 574468 4960354 FTW_0580 Francisella tularensis subsp. tularensis WY96-3418 beta-lactamase superfamily hydrolase YP_001121608.1 573506 D 418136 CDS YP_001121609.1 134301641 4960330 574480..574809 1 NC_009257.1 hypothetical protein 574809 4960330 FTW_0581 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121609.1 574480 D 418136 CDS YP_001121610.1 134301642 4960399 574806..575618 1 NC_009257.1 hypothetical protein 575618 4960399 FTW_0582 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121610.1 574806 D 418136 CDS YP_001121611.1 134301643 4960406 575615..576313 1 NC_009257.1 hypothetical protein 576313 4960406 FTW_0583 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121611.1 575615 D 418136 CDS YP_001121612.1 134301644 4960359 576324..576914 1 NC_009257.1 hypothetical protein 576914 4960359 FTW_0584 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121612.1 576324 D 418136 CDS YP_001121613.1 134301645 4960536 complement(576918..577889) 1 NC_009257.1 KpsF/GutQ family sugar isomerase 577889 4960536 FTW_0585 Francisella tularensis subsp. tularensis WY96-3418 KpsF/GutQ family sugar isomerase YP_001121613.1 576918 R 418136 CDS YP_001121614.1 134301646 4960290 578026..578694 1 NC_009257.1 D-ribulose-phosphate 3-epimerase 578694 rpe 4960290 rpe Francisella tularensis subsp. tularensis WY96-3418 D-ribulose-phosphate 3-epimerase YP_001121614.1 578026 D 418136 CDS YP_001121615.1 134301647 4960093 578699..580069 1 NC_009257.1 sugar transferase 580069 4960093 FTW_0587 Francisella tularensis subsp. tularensis WY96-3418 sugar transferase YP_001121615.1 578699 D 418136 CDS YP_001121616.1 134301648 4960013 580062..581081 1 NC_009257.1 UDP-glucose 4-epimerase 581081 galE 4960013 galE Francisella tularensis subsp. tularensis WY96-3418 UDP-glucose 4-epimerase YP_001121616.1 580062 D 418136 CDS YP_001121617.1 134301649 4959748 581085..582314 1 NC_009257.1 glycosyl transferase family protein 582314 4959748 FTW_0589 Francisella tularensis subsp. tularensis WY96-3418 glycosyl transferase family protein YP_001121617.1 581085 D 418136 CDS YP_001121618.1 134301650 4959520 582311..583993 1 NC_009257.1 ABC transporter ATP-binding and membrane protein 583993 4959520 FTW_0590 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter ATP-binding and membrane protein YP_001121618.1 582311 D 418136 CDS YP_001121619.1 134301651 4960466 584007..585293 1 NC_009257.1 HAD superfamily hydrolase/phosphatase 585293 4960466 FTW_0591 Francisella tularensis subsp. tularensis WY96-3418 HAD superfamily hydrolase/phosphatase YP_001121619.1 584007 D 418136 CDS YP_001121620.1 134301652 4960479 585286..585915 1 NC_009257.1 hypothetical protein 585915 4960479 FTW_0592 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121620.1 585286 D 418136 CDS YP_001121621.1 134301653 4959051 585919..586680 1 NC_009257.1 hypothetical protein 586680 4959051 FTW_0593 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121621.1 585919 D 418136 CDS YP_001121622.1 134301654 4959254 586689..587648 1 NC_009257.1 glycosyl transferase group 2 family protein 587648 4959254 FTW_0594 Francisella tularensis subsp. tularensis WY96-3418 glycosyl transferase group 2 family protein YP_001121622.1 586689 D 418136 CDS YP_001121623.1 134301655 4958897 587665..588672 1 NC_009257.1 glycosyl transferase group 2 family protein 588672 4958897 FTW_0595 Francisella tularensis subsp. tularensis WY96-3418 glycosyl transferase group 2 family protein YP_001121623.1 587665 D 418136 CDS YP_001121624.1 134301656 4959055 588675..589688 1 NC_009257.1 glycosyl transferases group 1 family protein 589688 4959055 FTW_0596 Francisella tularensis subsp. tularensis WY96-3418 glycosyl transferases group 1 family protein YP_001121624.1 588675 D 418136 CDS YP_001121625.1 134301657 4959411 589707..590369 1 NC_009257.1 HAD family hydrolase 590369 4959411 FTW_0597 Francisella tularensis subsp. tularensis WY96-3418 HAD family hydrolase YP_001121625.1 589707 D 418136 CDS YP_001121626.1 134301658 4958955 complement(590651..591757) 1 NC_009257.1 PfkB family kinase 591757 4958955 FTW_0598 Francisella tularensis subsp. tularensis WY96-3418 PfkB family kinase YP_001121626.1 590651 R 418136 CDS YP_001121627.1 134301659 4958926 591960..592778 1 NC_009257.1 S51 peptidase family protein 592778 4958926 FTW_0599 Francisella tularensis subsp. tularensis WY96-3418 S51 peptidase family protein YP_001121627.1 591960 D 418136 CDS YP_001121628.1 134301660 4959452 592994..593857 1 NC_009257.1 putative asparaginase 593857 4959452 FTW_0600 Francisella tularensis subsp. tularensis WY96-3418 putative asparaginase YP_001121628.1 592994 D 418136 CDS YP_001121629.1 134301661 4959586 594529..595785 1 NC_009257.1 major facilitator transporter 595785 4959586 FTW_0601 Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001121629.1 594529 D 418136 CDS YP_001121630.1 134301662 4959194 595870..597078 1 NC_009257.1 capsule biosynthesis protein capB 597078 capB 4959194 capB Francisella tularensis subsp. tularensis WY96-3418 capsule biosynthesis protein capB YP_001121630.1 595870 D 418136 CDS YP_001121631.1 134301663 4958921 597103..597567 1 NC_009257.1 capsule biosynthesis protein CapC 597567 4958921 FTW_0603 Francisella tularensis subsp. tularensis WY96-3418 capsule biosynthesis protein CapC YP_001121631.1 597103 D 418136 CDS YP_001121632.1 134301664 4959186 597569..598780 1 NC_009257.1 hypothetical protein 598780 4959186 FTW_0604 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121632.1 597569 D 418136 CDS YP_001121633.1 134301665 4959197 598849..600963 1 NC_009257.1 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 600963 4959197 FTW_0605 Francisella tularensis subsp. tularensis WY96-3418 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase YP_001121633.1 598849 D 418136 CDS YP_001121634.1 134301666 4959189 complement(600971..601573) 1 NC_009257.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 601573 recR 4959189 recR Francisella tularensis subsp. tularensis WY96-3418 recombination protein RecR YP_001121634.1 600971 R 418136 CDS YP_001121635.1 134301667 4959224 complement(601573..601911) 1 NC_009257.1 hypothetical protein 601911 4959224 FTW_0607 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121635.1 601573 R 418136 CDS YP_001121636.1 134301668 4959228 complement(601921..603036) 1 NC_009257.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 603036 murG 4959228 murG Francisella tularensis subsp. tularensis WY96-3418 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_001121636.1 601921 R 418136 CDS YP_001121637.1 134301669 4959052 603140..603520 1 NC_009257.1 glycine cleavage system protein H 603520 gcvH1 4959052 gcvH1 Francisella tularensis subsp. tularensis WY96-3418 glycine cleavage system protein H YP_001121637.1 603140 D 418136 CDS YP_001121638.1 134301670 4959375 603510..603806 1 NC_009257.1 hypothetical protein 603806 4959375 FTW_0610 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121638.1 603510 D 418136 CDS YP_001121639.1 134301671 4959296 complement(603892..605682) 1 NC_009257.1 chitin binding domain-containing protein 605682 4959296 FTW_0611 Francisella tularensis subsp. tularensis WY96-3418 chitin binding domain-containing protein YP_001121639.1 603892 R 418136 CDS YP_001121640.1 134301672 4959518 606122..608026 1 NC_009257.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 608026 thrS 4959518 thrS Francisella tularensis subsp. tularensis WY96-3418 threonyl-tRNA synthetase YP_001121640.1 606122 D 418136 CDS YP_001121641.1 134301673 4958791 608033..608569 1 NC_009257.1 translation initiation factor IF-3 608569 infC 4958791 infC Francisella tularensis subsp. tularensis WY96-3418 translation initiation factor IF-3 YP_001121641.1 608033 D 418136 CDS YP_001121642.1 134301674 4959525 608612..608809 1 NC_009257.1 50S ribosomal protein L35 608809 rpmI 4959525 rpmI Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L35 YP_001121642.1 608612 D 418136 CDS YP_001121643.1 134301675 4959300 608845..609201 1 NC_009257.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 609201 rplT 4959300 rplT Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L20 YP_001121643.1 608845 D 418136 CDS YP_001121644.1 134301676 4959529 609243..609947 1 NC_009257.1 hypothetical protein 609947 4959529 FTW_0616 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121644.1 609243 D 418136 CDS YP_001121645.1 134301677 4959572 join(610239..610568,610568..611119) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 611119 4959572 FTW_0617 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121645.1 610239 D 418136 CDS YP_001121646.1 134301678 4959591 611748..611936 1 NC_009257.1 hypothetical protein 611936 4959591 FTW_0619 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121646.1 611748 D 418136 CDS YP_001121647.1 134301679 4959505 611929..612681 1 NC_009257.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 612681 kdsB 4959505 kdsB Francisella tularensis subsp. tularensis WY96-3418 3-deoxy-manno-octulosonate cytidylyltransferase YP_001121647.1 611929 D 418136 CDS YP_001121648.1 134301680 4959592 612674..613069 1 NC_009257.1 hypothetical protein 613069 4959592 FTW_0621 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121648.1 612674 D 418136 CDS YP_001121649.1 134301681 4959593 complement(613066..614214) 1 NC_009257.1 galactokinase 614214 galK 4959593 galK Francisella tularensis subsp. tularensis WY96-3418 galactokinase YP_001121649.1 613066 R 418136 CDS YP_001121650.1 134301682 4959619 complement(614217..615242) 1 NC_009257.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 615242 galT 4959619 galT Francisella tularensis subsp. tularensis WY96-3418 galactose-1-phosphate uridylyltransferase YP_001121650.1 614217 R 418136 CDS YP_001121651.1 134301683 4959604 615333..616715 1 NC_009257.1 major facilitator superfamily galactose-proton symporter 616715 galP1 4959604 galP1 Francisella tularensis subsp. tularensis WY96-3418 major facilitator superfamily galactose-proton symporter YP_001121651.1 615333 D 418136 CDS YP_001121652.1 134301684 4959620 616747..618141 1 NC_009257.1 major facilitator superfamily galactose-proton symporter 618141 galP2 4959620 galP2 Francisella tularensis subsp. tularensis WY96-3418 major facilitator superfamily galactose-proton symporter YP_001121652.1 616747 D 418136 CDS YP_001121653.1 134301685 4959622 618236..618514 1 NC_009257.1 peptidyl-prolyl cis-trans isomerase C 618514 ppiC 4959622 ppiC Francisella tularensis subsp. tularensis WY96-3418 peptidyl-prolyl cis-trans isomerase C YP_001121653.1 618236 D 418136 CDS YP_001121654.1 134301686 4959642 618579..620288 1 NC_009257.1 cold-shock DEAD/DEAH box helicase 620288 deaD 4959642 deaD Francisella tularensis subsp. tularensis WY96-3418 cold-shock DEAD/DEAH box helicase YP_001121654.1 618579 D 418136 CDS YP_001121655.1 134301687 4959631 620405..620977 1 NC_009257.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 620977 gmk 4959631 gmk Francisella tularensis subsp. tularensis WY96-3418 guanylate kinase YP_001121655.1 620405 D 418136 CDS YP_001121656.1 134301688 4959661 620998..622023 1 NC_009257.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 622023 nadA 4959661 nadA Francisella tularensis subsp. tularensis WY96-3418 quinolinate synthetase YP_001121656.1 620998 D 418136 CDS YP_001121657.1 134301689 4959660 622032..622895 1 NC_009257.1 nicotinate-nucleotide pyrophosphorylase 622895 nadC 4959660 nadC Francisella tularensis subsp. tularensis WY96-3418 nicotinate-nucleotide pyrophosphorylase YP_001121657.1 622032 D 418136 CDS YP_001121658.1 134301690 4959679 622898..624385 1 NC_009257.1 L-aspartate oxidase 624385 nadB 4959679 nadB Francisella tularensis subsp. tularensis WY96-3418 L-aspartate oxidase YP_001121658.1 622898 D 418136 CDS YP_001121659.1 134301691 4959712 complement(626480..626926) 1 NC_009257.1 hypothetical protein 626926 4959712 FTW_0636 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121659.1 626480 R 418136 CDS YP_001121660.1 134301692 4959721 627080..627370 1 NC_009257.1 chorismate mutase family protein 627370 4959721 FTW_0637 Francisella tularensis subsp. tularensis WY96-3418 chorismate mutase family protein YP_001121660.1 627080 D 418136 CDS YP_001121661.1 134301693 4959718 627399..627869 1 NC_009257.1 glutathione peroxidase 627869 4959718 FTW_0638 Francisella tularensis subsp. tularensis WY96-3418 glutathione peroxidase YP_001121661.1 627399 D 418136 CDS YP_001121662.1 134301694 4959717 629074..630051 1 NC_009257.1 mandelate racemase/muconate lactonizing protein 630051 4959717 FTW_0641 Francisella tularensis subsp. tularensis WY96-3418 mandelate racemase/muconate lactonizing protein YP_001121662.1 629074 D 418136 CDS YP_001121663.1 134301695 4959766 630157..630804 1 NC_009257.1 hypothetical protein 630804 4959766 FTW_0642 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121663.1 630157 D 418136 CDS YP_001121664.1 134301696 4959758 complement(630815..630943) 1 NC_009257.1 hypothetical protein 630943 4959758 FTW_0643 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121664.1 630815 R 418136 CDS YP_001121665.1 134301697 4959757 630903..631082 1 NC_009257.1 hypothetical protein 631082 4959757 FTW_0644 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121665.1 630903 D 418136 CDS YP_001121666.1 134301698 4959759 631141..632604 1 NC_009257.1 YjeF-like protein/carbohydrate kinase 632604 4959759 FTW_0645 Francisella tularensis subsp. tularensis WY96-3418 YjeF-like protein/carbohydrate kinase YP_001121666.1 631141 D 418136 CDS YP_001121667.1 134301699 4959760 complement(632639..633007) 1 NC_009257.1 S4 domain-containing protein 633007 4959760 FTW_0646 Francisella tularensis subsp. tularensis WY96-3418 S4 domain-containing protein YP_001121667.1 632639 R 418136 CDS YP_001121668.1 134301700 4959761 636167..638437 1 NC_009257.1 lipoprotein 638437 4959761 FTW_0649 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001121668.1 636167 D 418136 CDS YP_001121669.1 134301701 4959764 639118..639933 1 NC_009257.1 hypothetical protein 639933 4959764 FTW_0650 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121669.1 639118 D 418136 CDS YP_001121670.1 134301703 4959727 complement(640032..640451) 1 NC_009257.1 hypothetical protein 640451 4959727 FTW_0652 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121670.1 640032 R 418136 CDS YP_001121671.1 134301702 4959782 640327..640464 1 NC_009257.1 hypothetical protein 640464 4959782 FTW_0651 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121671.1 640327 D 418136 CDS YP_001121672.1 134301704 4959785 complement(641725..642570) 1 NC_009257.1 RND efflux transporter 642570 4959785 FTW_0655 Francisella tularensis subsp. tularensis WY96-3418 RND efflux transporter YP_001121672.1 641725 R 418136 CDS YP_001121673.1 134301705 4959787 642699..642818 1 NC_009257.1 hypothetical protein 642818 4959787 FTW_0656 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121673.1 642699 D 418136 CDS YP_001121674.1 134301706 4959797 642962..643681 1 NC_009257.1 IclR family transcriptional regulator 643681 4959797 FTW_0657 Francisella tularensis subsp. tularensis WY96-3418 IclR family transcriptional regulator YP_001121674.1 642962 D 418136 CDS YP_001121675.1 134301707 4959807 complement(643741..644727) 1 NC_009257.1 hypothetical protein 644727 4959807 FTW_0658 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121675.1 643741 R 418136 CDS YP_001121676.1 134301708 4959839 644933..645919 1 NC_009257.1 hypothetical protein 645919 4959839 FTW_0659 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121676.1 644933 D 418136 CDS YP_001121677.1 134301709 4959810 complement(645990..646193) 1 NC_009257.1 cold shock DNA-binding domain-containing protein 646193 4959810 FTW_0660 Francisella tularensis subsp. tularensis WY96-3418 cold shock DNA-binding domain-containing protein YP_001121677.1 645990 R 418136 CDS YP_001121678.1 134301710 4959822 646965..647165 1 NC_009257.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 647165 rpsU 4959822 rpsU Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S21 YP_001121678.1 646965 D 418136 CDS YP_001121679.1 134301711 4959861 complement(647223..647390) 1 NC_009257.1 hypothetical protein 647390 4959861 FTW_0664 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121679.1 647223 R 418136 CDS YP_001121680.1 134301712 4959627 648036..648527 1 NC_009257.1 hypothetical protein 648527 4959627 FTW_0665 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121680.1 648036 D 418136 CDS YP_001121681.1 134301713 4959893 648618..649757 1 NC_009257.1 cation-efflux family protein 649757 4959893 FTW_0666 Francisella tularensis subsp. tularensis WY96-3418 cation-efflux family protein YP_001121681.1 648618 D 418136 CDS YP_001121682.1 134301714 4959900 649774..650637 1 NC_009257.1 UTP--glucose-1-phosphate uridylyltransferase 650637 galU 4959900 galU Francisella tularensis subsp. tularensis WY96-3418 UTP--glucose-1-phosphate uridylyltransferase YP_001121682.1 649774 D 418136 CDS YP_001121683.1 134301715 4959903 652110..653027 1 NC_009257.1 hypothetical protein 653027 4959903 FTW_0670 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121683.1 652110 D 418136 CDS YP_001121684.1 134301716 4959911 complement(653030..653236) 1 NC_009257.1 lipoprotein 653236 4959911 FTW_0671 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001121684.1 653030 R 418136 CDS YP_001121685.1 134301717 4959910 complement(653321..653614) 1 NC_009257.1 hypothetical protein 653614 4959910 FTW_0672 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121685.1 653321 R 418136 CDS YP_001121686.1 134301718 4959915 complement(653636..654685) 1 NC_009257.1 DNA replication and repair protein RecF 654685 4959915 FTW_0673 Francisella tularensis subsp. tularensis WY96-3418 DNA replication and repair protein RecF YP_001121686.1 653636 R 418136 CDS YP_001121687.1 134301719 4959887 complement(654689..655435) 1 NC_009257.1 tatD family hydrolase 655435 4959887 FTW_0674 Francisella tularensis subsp. tularensis WY96-3418 tatD family hydrolase YP_001121687.1 654689 R 418136 CDS YP_001121688.1 134301720 4959930 655628..657712 1 NC_009257.1 glycyl-tRNA synthetase subunit beta 657712 glyS 4959930 glyS Francisella tularensis subsp. tularensis WY96-3418 glycyl-tRNA synthetase subunit beta YP_001121688.1 655628 D 418136 CDS YP_001121689.1 134301721 4959923 join(657852..658181,658181..658732) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 658732 4959923 FTW_0676 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121689.1 657852 D 418136 CDS YP_001121690.1 134301722 4959934 complement(658928..659923) 1 NC_009257.1 hypothetical protein 659923 4959934 FTW_0678 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121690.1 658928 R 418136 CDS YP_001121691.1 134301723 4959960 complement(join(660831..661382,661382..661711)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 661711 4959960 FTW_0680 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121691.1 660831 R 418136 CDS YP_001121692.1 134301724 4959966 complement(662465..662887) 1 NC_009257.1 hypothetical protein 662887 4959966 FTW_0684 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121692.1 662465 R 418136 CDS YP_001121693.1 134301725 4959250 complement(662991..663740) 1 NC_009257.1 NAD+ synthetase 663740 nadE 4959250 nadE Francisella tularensis subsp. tularensis WY96-3418 NAD+ synthetase YP_001121693.1 662991 R 418136 CDS YP_001121694.1 134301726 4958929 complement(663851..665323) 1 NC_009257.1 outer membrane efflux protein 665323 4958929 FTW_0686 Francisella tularensis subsp. tularensis WY96-3418 outer membrane efflux protein YP_001121694.1 663851 R 418136 CDS YP_001121695.1 134301727 4959243 complement(665333..666355) 1 NC_009257.1 efflux pump protein 666355 4959243 FTW_0687 Francisella tularensis subsp. tularensis WY96-3418 efflux pump protein YP_001121695.1 665333 R 418136 CDS YP_001121696.1 134301728 4958750 complement(666377..667906) 1 NC_009257.1 drug:H+ antiporter-1 family protein 667906 4958750 FTW_0688 Francisella tularensis subsp. tularensis WY96-3418 drug:H+ antiporter-1 family protein YP_001121696.1 666377 R 418136 CDS YP_001121697.1 134301729 4959395 668050..668898 1 NC_009257.1 AraC family transcriptional regulator 668898 4959395 FTW_0689 Francisella tularensis subsp. tularensis WY96-3418 AraC family transcriptional regulator YP_001121697.1 668050 D 418136 CDS YP_001121698.1 134301730 4960011 complement(668886..670577) 1 NC_009257.1 amino acid adenylase 670577 4960011 FTW_0690 Francisella tularensis subsp. tularensis WY96-3418 amino acid adenylase YP_001121698.1 668886 R 418136 CDS YP_001121699.1 134301731 4959148 complement(670685..672172) 1 NC_009257.1 amino acid/peptide transporter (peptide:H+ symporter) 672172 4959148 FTW_0691 Francisella tularensis subsp. tularensis WY96-3418 amino acid/peptide transporter (peptide:H+ symporter) YP_001121699.1 670685 R 418136 CDS YP_001121700.1 134301732 4959041 complement(672402..673130) 1 NC_009257.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 673130 4959041 FTW_0692 Francisella tularensis subsp. tularensis WY96-3418 16S ribosomal RNA methyltransferase RsmE YP_001121700.1 672402 R 418136 CDS YP_001121701.1 134301733 4958755 673201..673887 1 NC_009257.1 hypothetical protein 673887 4958755 FTW_0693 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121701.1 673201 D 418136 CDS YP_001121702.1 134301734 4958807 complement(673877..674575) 1 NC_009257.1 hypothetical protein 674575 4958807 FTW_0694 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121702.1 673877 R 418136 CDS YP_001121703.1 134301735 4959420 complement(674580..675305) 1 NC_009257.1 hypothetical protein 675305 4959420 FTW_0695 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121703.1 674580 R 418136 CDS YP_001121704.1 134301736 4958685 complement(675315..676076) 1 NC_009257.1 ABC transporter ATP-binding protein 676076 4958685 FTW_0696 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter ATP-binding protein YP_001121704.1 675315 R 418136 CDS YP_001121705.1 134301737 4959479 complement(676091..677191) 1 NC_009257.1 ABC transporter membrane protein 677191 4959479 FTW_0697 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter membrane protein YP_001121705.1 676091 R 418136 CDS YP_001121706.1 134301738 4959231 complement(677266..678078) 1 NC_009257.1 hypothetical protein 678078 4959231 FTW_0698 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121706.1 677266 R 418136 CDS YP_001121707.1 134301739 4960024 complement(678056..679009) 1 NC_009257.1 RluA family pseudouridine synthase 679009 4960024 FTW_0699 Francisella tularensis subsp. tularensis WY96-3418 RluA family pseudouridine synthase YP_001121707.1 678056 R 418136 CDS YP_001121708.1 134301740 4959113 679143..679967 1 NC_009257.1 lipoprotein 679967 4959113 FTW_0700 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001121708.1 679143 D 418136 CDS YP_001121709.1 134301741 4959279 complement(683322..684575) 1 NC_009257.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 684575 glyA 4959279 glyA Francisella tularensis subsp. tularensis WY96-3418 serine hydroxymethyltransferase YP_001121709.1 683322 R 418136 CDS YP_001121710.1 134301742 4960033 684679..685227 1 NC_009257.1 hypothetical protein 685227 4960033 FTW_0704 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121710.1 684679 D 418136 CDS YP_001121711.1 134301743 4959985 complement(685242..686513) 1 NC_009257.1 hypothetical protein 686513 4959985 FTW_0705 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121711.1 685242 R 418136 CDS YP_001121712.1 134301744 4960034 686721..688052 1 NC_009257.1 hypothetical protein 688052 4960034 FTW_0706 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121712.1 686721 D 418136 CDS YP_001121713.1 134301745 4959084 complement(688078..688968) 1 NC_009257.1 glycosyl transferase family protein 688968 4959084 FTW_0707 Francisella tularensis subsp. tularensis WY96-3418 glycosyl transferase family protein YP_001121713.1 688078 R 418136 CDS YP_001121714.1 134301746 4958987 complement(688976..690064) 1 NC_009257.1 hypothetical protein 690064 4958987 FTW_0708 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121714.1 688976 R 418136 CDS YP_001121715.1 134301747 4959340 690234..691298 1 NC_009257.1 glycosyl transferase family protein 691298 4959340 FTW_0709 Francisella tularensis subsp. tularensis WY96-3418 glycosyl transferase family protein YP_001121715.1 690234 D 418136 CDS YP_001121716.1 134301748 4959154 complement(691299..692396) 1 NC_009257.1 choloylglycine hydrolase family protein 692396 4959154 FTW_0710 Francisella tularensis subsp. tularensis WY96-3418 choloylglycine hydrolase family protein YP_001121716.1 691299 R 418136 CDS YP_001121717.1 134301749 4958688 complement(join(693824..694375,694375..694704)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 694704 4958688 FTW_0713 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121717.1 693824 R 418136 CDS YP_001121718.1 134301750 4958842 complement(694833..696029) 1 NC_009257.1 tRNA(Ile)-lysidine synthase 696029 4958842 FTW_0715 Francisella tularensis subsp. tularensis WY96-3418 tRNA(Ile)-lysidine synthase YP_001121718.1 694833 R 418136 CDS YP_001121719.1 134301751 4959118 complement(696030..697265) 1 NC_009257.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 697265 4959118 FTW_0716 Francisella tularensis subsp. tularensis WY96-3418 D-3-phosphoglycerate dehydrogenase YP_001121719.1 696030 R 418136 CDS YP_001121720.1 134301752 4958797 complement(697277..698101) 1 NC_009257.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 698101 thyA 4958797 thyA Francisella tularensis subsp. tularensis WY96-3418 thymidylate synthase YP_001121720.1 697277 R 418136 CDS YP_001121721.1 134301753 4959251 complement(698086..698892) 1 NC_009257.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 698892 lgt 4959251 lgt Francisella tularensis subsp. tularensis WY96-3418 prolipoprotein diacylglyceryl transferase YP_001121721.1 698086 R 418136 CDS YP_001121722.1 134301754 4959240 complement(698907..701564) 1 NC_009257.1 ribonuclease 701564 4959240 FTW_0719 Francisella tularensis subsp. tularensis WY96-3418 ribonuclease YP_001121722.1 698907 R 418136 CDS YP_001121723.1 134301755 4959425 701814..702989 1 NC_009257.1 cysteine desulfarase 702989 4959425 FTW_0720 Francisella tularensis subsp. tularensis WY96-3418 cysteine desulfarase YP_001121723.1 701814 D 418136 CDS YP_001121724.1 134301756 4959136 702982..703311 1 NC_009257.1 hypothetical protein 703311 4959136 FTW_0721 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121724.1 702982 D 418136 CDS YP_001121725.1 134301757 4959235 703295..703993 1 NC_009257.1 DNA repair protein RecO 703993 recO 4959235 recO Francisella tularensis subsp. tularensis WY96-3418 DNA repair protein RecO YP_001121725.1 703295 D 418136 CDS YP_001121726.1 134301758 4959225 complement(704069..704716) 1 NC_009257.1 hypothetical protein 704716 4959225 FTW_0723 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121726.1 704069 R 418136 CDS YP_001121727.1 134301759 4959121 complement(704772..705398) 1 NC_009257.1 hypothetical protein 705398 4959121 FTW_0724 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121727.1 704772 R 418136 CDS YP_001121728.1 134301760 4958967 complement(705405..705671) 1 NC_009257.1 hypothetical protein 705671 4958967 FTW_0725 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121728.1 705405 R 418136 CDS YP_001121729.1 134301761 4959405 complement(705674..706222) 1 NC_009257.1 5,10-methenyltetrahydrofolate synthetase 706222 4959405 FTW_0726 Francisella tularensis subsp. tularensis WY96-3418 5,10-methenyltetrahydrofolate synthetase YP_001121729.1 705674 R 418136 CDS YP_001121730.1 134301762 4958840 706662..707198 1 NC_009257.1 hypothetical protein 707198 4958840 FTW_0727 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121730.1 706662 D 418136 CDS YP_001121731.1 134301763 4959410 707207..708418 1 NC_009257.1 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase 708418 4959410 FTW_0728 Francisella tularensis subsp. tularensis WY96-3418 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase YP_001121731.1 707207 D 418136 CDS YP_001121732.1 134301764 4959226 708408..709643 1 NC_009257.1 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase 709643 4959226 FTW_0729 Francisella tularensis subsp. tularensis WY96-3418 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase YP_001121732.1 708408 D 418136 CDS YP_001121733.1 134301765 4958901 709665..710126 1 NC_009257.1 hypothetical protein 710126 4958901 FTW_0730 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121733.1 709665 D 418136 CDS YP_001121734.1 134301766 4959413 710152..711168 1 NC_009257.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 711168 queA 4959413 queA Francisella tularensis subsp. tularensis WY96-3418 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_001121734.1 710152 D 418136 CDS YP_001121735.1 134301767 4959453 711804..712595 1 NC_009257.1 HAD family hydrolase 712595 4959453 FTW_0732 Francisella tularensis subsp. tularensis WY96-3418 HAD family hydrolase YP_001121735.1 711804 D 418136 CDS YP_001121736.1 134301768 4958911 complement(712849..713562) 1 NC_009257.1 YhhQ family membrane protein 713562 4958911 FTW_0733 Francisella tularensis subsp. tularensis WY96-3418 YhhQ family membrane protein YP_001121736.1 712849 R 418136 CDS YP_001121737.1 134301769 4958912 713678..714061 1 NC_009257.1 lactoylglutathione lyase 714061 gloA 4958912 gloA Francisella tularensis subsp. tularensis WY96-3418 lactoylglutathione lyase YP_001121737.1 713678 D 418136 CDS YP_001121738.1 134301770 4959050 714061..714453 1 NC_009257.1 hypothetical protein 714453 4959050 FTW_0735 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121738.1 714061 D 418136 CDS YP_001121739.1 134301771 4959916 join(714515..714844,714844..715395) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 715395 4959916 FTW_0736 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121739.1 714515 D 418136 CDS YP_001121740.1 134301772 4958736 715832..716440 1 NC_009257.1 hypothetical protein 716440 4958736 FTW_0738 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121740.1 715832 D 418136 CDS YP_001121741.1 134301773 4958744 716485..717036 1 NC_009257.1 hypothetical protein 717036 4958744 FTW_0739 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121741.1 716485 D 418136 CDS YP_001121742.1 134301774 4960050 717239..718636 1 NC_009257.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 718636 engA 4960050 engA Francisella tularensis subsp. tularensis WY96-3418 GTP-binding protein EngA YP_001121742.1 717239 D 418136 CDS YP_001121743.1 134301775 4960049 718605..719909 1 NC_009257.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase 719909 murA 4960049 murA Francisella tularensis subsp. tularensis WY96-3418 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001121743.1 718605 D 418136 CDS YP_001121744.1 134301776 4959160 719917..720765 1 NC_009257.1 UDP-N-acetylenolpyruvoylglucosamine reductase 720765 murB 4959160 murB Francisella tularensis subsp. tularensis WY96-3418 UDP-N-acetylenolpyruvoylglucosamine reductase YP_001121744.1 719917 D 418136 CDS YP_001121745.1 134301777 4959063 720844..721719 1 NC_009257.1 hypothetical protein 721719 4959063 FTW_0743 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121745.1 720844 D 418136 CDS YP_001121746.1 134301778 4959456 complement(721721..722548) 1 NC_009257.1 hypothetical protein 722548 4959456 FTW_0744 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121746.1 721721 R 418136 CDS YP_001121747.1 134301779 4959042 723547..723678 1 NC_009257.1 hypothetical protein 723678 4959042 FTW_0747 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121747.1 723547 D 418136 CDS YP_001121748.1 134301780 4958774 complement(723695..724033) 1 NC_009257.1 histidine triad (HIT) family protein 724033 4958774 FTW_0748 Francisella tularensis subsp. tularensis WY96-3418 histidine triad (HIT) family protein YP_001121748.1 723695 R 418136 CDS YP_001121749.1 134301781 4958899 complement(724039..725697) 1 NC_009257.1 2-polyprenylphenol 6-hydroxylase 725697 ubiB 4958899 ubiB Francisella tularensis subsp. tularensis WY96-3418 2-polyprenylphenol 6-hydroxylase YP_001121749.1 724039 R 418136 CDS YP_001121750.1 134301782 4959246 complement(725690..726277) 1 NC_009257.1 hypothetical protein 726277 4959246 FTW_0750 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121750.1 725690 R 418136 CDS YP_001121751.1 134301783 4959135 complement(726279..727031) 1 NC_009257.1 menaquinone biosynthesis methyltransferase 727031 ubiE 4959135 ubiE Francisella tularensis subsp. tularensis WY96-3418 menaquinone biosynthesis methyltransferase YP_001121751.1 726279 R 418136 CDS YP_001121752.1 134301784 4959390 727125..728141 1 NC_009257.1 glucokinase 728141 glk 4959390 glk Francisella tularensis subsp. tularensis WY96-3418 glucokinase YP_001121752.1 727125 D 418136 CDS YP_001121753.1 134301785 4958793 complement(728143..728406) 1 NC_009257.1 hypothetical protein 728406 4958793 FTW_0753 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121753.1 728143 R 418136 CDS YP_001121754.1 134301786 4958781 complement(728480..729010) 1 NC_009257.1 intracellular septation protein A family protein 729010 4958781 FTW_0754 Francisella tularensis subsp. tularensis WY96-3418 intracellular septation protein A family protein YP_001121754.1 728480 R 418136 CDS YP_001121755.1 134301787 4958733 729071..729685 1 NC_009257.1 Sua5/YciO/YrdC/YwlC family protein 729685 4958733 FTW_0755 Francisella tularensis subsp. tularensis WY96-3418 Sua5/YciO/YrdC/YwlC family protein YP_001121755.1 729071 D 418136 CDS YP_001121756.1 134301788 4958777 729735..730337 1 NC_009257.1 hypothetical protein 730337 4958777 FTW_0756 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121756.1 729735 D 418136 CDS YP_001121757.1 134301789 4958679 complement(730334..731557) 1 NC_009257.1 major facilitator transporter 731557 4958679 FTW_0757 Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001121757.1 730334 R 418136 CDS YP_001121758.1 134301790 4958973 complement(731574..733598) 1 NC_009257.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 733598 metG 4958973 metG Francisella tularensis subsp. tularensis WY96-3418 methionyl-tRNA synthetase YP_001121758.1 731574 R 418136 CDS YP_001121759.1 134301791 4959693 complement(734168..734704) 1 NC_009257.1 FMN reductase, NADPH-dependent 734704 4959693 FTW_0759 Francisella tularensis subsp. tularensis WY96-3418 FMN reductase, NADPH-dependent YP_001121759.1 734168 R 418136 CDS YP_001121760.1 134301792 4959386 740426..741235 1 NC_009257.1 hypothetical protein 741235 4959386 FTW_0761 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121760.1 740426 D 418136 CDS YP_001121761.1 134301793 4959248 complement(741530..742585) 1 NC_009257.1 hypothetical protein 742585 4959248 FTW_0762 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121761.1 741530 R 418136 CDS YP_001121762.1 134301794 4959245 complement(742699..743334) 1 NC_009257.1 M50 family peptidase 743334 4959245 FTW_0763 Francisella tularensis subsp. tularensis WY96-3418 M50 family peptidase YP_001121762.1 742699 R 418136 CDS YP_001121763.1 134301795 4960073 complement(744509..745858) 1 NC_009257.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 745858 4960073 FTW_0766 Francisella tularensis subsp. tularensis WY96-3418 glutamate dehydrogenase YP_001121763.1 744509 R 418136 CDS YP_001121764.1 134301796 4958906 747210..747899 1 NC_009257.1 hypothetical protein 747899 4958906 FTW_0769 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121764.1 747210 D 418136 CDS YP_001121765.1 134301797 4959083 747912..749096 1 NC_009257.1 diaminopimelate decarboxylase 749096 lysA 4959083 lysA Francisella tularensis subsp. tularensis WY96-3418 diaminopimelate decarboxylase YP_001121765.1 747912 D 418136 CDS YP_001121766.1 134301798 4959336 749108..750487 1 NC_009257.1 amino acid transporter 750487 4959336 FTW_0771 Francisella tularensis subsp. tularensis WY96-3418 amino acid transporter YP_001121766.1 749108 D 418136 CDS YP_001121767.1 134301799 4960085 complement(750529..750768) 1 NC_009257.1 hypothetical protein 750768 4960085 FTW_0772 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121767.1 750529 R 418136 CDS YP_001121768.1 134301800 4958874 complement(750971..751543) 1 NC_009257.1 methylated-DNA--protein-cysteine methyltransferase family protein 751543 4958874 FTW_0773 Francisella tularensis subsp. tularensis WY96-3418 methylated-DNA--protein-cysteine methyltransferase family protein YP_001121768.1 750971 R 418136 CDS YP_001121769.1 134301801 4958819 753710..754309 1 NC_009257.1 CDP-alcohol phosphatidyltransferase 754309 4958819 FTW_0776 Francisella tularensis subsp. tularensis WY96-3418 CDP-alcohol phosphatidyltransferase YP_001121769.1 753710 D 418136 CDS YP_001121770.1 134301802 4958925 754281..754688 1 NC_009257.1 hypothetical protein 754688 4958925 FTW_0777 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121770.1 754281 D 418136 CDS YP_001121771.1 134301803 4960091 complement(754703..755398) 1 NC_009257.1 amino acid permease family protein 755398 4960091 FTW_0778 Francisella tularensis subsp. tularensis WY96-3418 amino acid permease family protein YP_001121771.1 754703 R 418136 CDS YP_001121772.1 134301804 4960090 755618..756544 1 NC_009257.1 chaperone protein DNA J 756544 4960090 FTW_0779 Francisella tularensis subsp. tularensis WY96-3418 chaperone protein DNA J YP_001121772.1 755618 D 418136 CDS YP_001121773.1 134301805 4960092 complement(756534..757418) 1 NC_009257.1 hypothetical protein 757418 4960092 FTW_0780 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121773.1 756534 R 418136 CDS YP_001121774.1 134301806 4959238 757609..758805 1 NC_009257.1 putative tryptophan/tyrosine permease family protein 758805 4959238 FTW_0781 Francisella tularensis subsp. tularensis WY96-3418 putative tryptophan/tyrosine permease family protein YP_001121774.1 757609 D 418136 CDS YP_001121775.1 134301807 4958884 758839..759195 1 NC_009257.1 hypothetical protein 759195 4958884 FTW_0782 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121775.1 758839 D 418136 CDS YP_001121776.1 134301808 4959514 759564..761507 1 NC_009257.1 putative GTP pyrophosphokinase 761507 4959514 FTW_0783 Francisella tularensis subsp. tularensis WY96-3418 putative GTP pyrophosphokinase YP_001121776.1 759564 D 418136 CDS YP_001121777.1 134301809 4959421 complement(761623..762255) 1 NC_009257.1 hypothetical protein 762255 4959421 FTW_0784 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121777.1 761623 R 418136 CDS YP_001121778.1 134301810 4958759 complement(762332..762910) 1 NC_009257.1 hypothetical protein 762910 4958759 FTW_0785 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121778.1 762332 R 418136 CDS YP_001121779.1 134301811 4960108 complement(763618..764343) 1 NC_009257.1 hypothetical protein 764343 4960108 FTW_0787 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121779.1 763618 R 418136 CDS YP_001121780.1 134301812 4960144 complement(764343..765221) 1 NC_009257.1 phage integrase family protein 765221 4960144 FTW_0788 Francisella tularensis subsp. tularensis WY96-3418 phage integrase family protein YP_001121780.1 764343 R 418136 CDS YP_001121781.1 134301813 4960169 complement(765231..766442) 1 NC_009257.1 aromatic amino acid transporter family protein 766442 4960169 FTW_0789 Francisella tularensis subsp. tularensis WY96-3418 aromatic amino acid transporter family protein YP_001121781.1 765231 R 418136 CDS YP_001121782.1 134301814 4960163 complement(766658..767689) 1 NC_009257.1 hypothetical protein 767689 4960163 FTW_0790 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121782.1 766658 R 418136 CDS YP_001121783.1 134301815 4960171 complement(767883..768326) 1 NC_009257.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 768326 secB1 4960171 secB1 Francisella tularensis subsp. tularensis WY96-3418 preprotein translocase subunit SecB YP_001121783.1 767883 R 418136 CDS YP_001121784.1 134301816 4960174 complement(768403..770937) 1 NC_009257.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 770937 mutS 4960174 mutS Francisella tularensis subsp. tularensis WY96-3418 DNA mismatch repair protein MutS YP_001121784.1 768403 R 418136 CDS YP_001121785.1 134301817 4960199 771104..772051 1 NC_009257.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 772051 accA 4960199 accA Francisella tularensis subsp. tularensis WY96-3418 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_001121785.1 771104 D 418136 CDS YP_001121786.1 134301818 4960189 772071..772574 1 NC_009257.1 hypothetical protein 772574 4960189 FTW_0794 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121786.1 772071 D 418136 CDS YP_001121787.1 134301819 4960480 772555..773568 1 NC_009257.1 prepilin-type N-terminal cleavage/methylation domain-containing protein 773568 4960480 FTW_0795 Francisella tularensis subsp. tularensis WY96-3418 prepilin-type N-terminal cleavage/methylation domain-containing protein YP_001121787.1 772555 D 418136 CDS YP_001121788.1 134301820 4960493 773577..775541 1 NC_009257.1 hypothetical protein 775541 4960493 FTW_0796 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121788.1 773577 D 418136 CDS YP_001121789.1 134301821 4960475 775538..776422 1 NC_009257.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 776422 murQ 4960475 murQ Francisella tularensis subsp. tularensis WY96-3418 N-acetylmuramic acid 6-phosphate etherase YP_001121789.1 775538 D 418136 CDS YP_001121790.1 134301822 4960210 776424..776819 1 NC_009257.1 hypothetical protein 776819 4960210 FTW_0798 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121790.1 776424 D 418136 CDS YP_001121791.1 134301823 4960244 complement(777113..777241) 1 NC_009257.1 hypothetical protein 777241 4960244 FTW_0799 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121791.1 777113 R 418136 CDS YP_001121792.1 134301824 4960256 777310..777936 1 NC_009257.1 lipoprotein 777936 4960256 FTW_0800 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001121792.1 777310 D 418136 CDS YP_001121793.1 134301825 4960288 778032..778346 1 NC_009257.1 hypothetical protein 778346 4960288 FTW_0801 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121793.1 778032 D 418136 CDS YP_001121794.1 134301827 4960281 complement(778733..780031) 1 NC_009257.1 monovalent cation:proton antiporter family protein 780031 4960281 FTW_0803 Francisella tularensis subsp. tularensis WY96-3418 monovalent cation:proton antiporter family protein YP_001121794.1 778733 R 418136 CDS YP_001121795.1 134301826 4960296 779841..779978 1 NC_009257.1 hypothetical protein 779978 4960296 FTW_0802 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121795.1 779841 D 418136 CDS YP_001121796.1 134301828 4960289 complement(780041..780766) 1 NC_009257.1 hypothetical protein 780766 4960289 FTW_0804 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121796.1 780041 R 418136 CDS YP_001121797.1 134301829 4960333 complement(780768..781772) 1 NC_009257.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 781772 trpS 4960333 trpS Francisella tularensis subsp. tularensis WY96-3418 tryptophanyl-tRNA synthetase YP_001121797.1 780768 R 418136 CDS YP_001121798.1 134301830 4959647 complement(782069..782683) 1 NC_009257.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 782683 coaE 4959647 coaE Francisella tularensis subsp. tularensis WY96-3418 dephospho-CoA kinase YP_001121798.1 782069 R 418136 CDS YP_001121799.1 134301831 4960334 782812..783948 1 NC_009257.1 hypothetical protein 783948 4960334 FTW_0807 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121799.1 782812 D 418136 CDS YP_001121800.1 134301832 4960340 784248..786929 1 NC_009257.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 786929 aceE 4960340 aceE Francisella tularensis subsp. tularensis WY96-3418 pyruvate dehydrogenase subunit E1 YP_001121800.1 784248 D 418136 CDS YP_001121801.1 134301833 4960382 786947..788842 1 NC_009257.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 788842 aceF 4960382 aceF Francisella tularensis subsp. tularensis WY96-3418 dihydrolipoamide acetyltransferase YP_001121801.1 786947 D 418136 CDS YP_001121802.1 134301834 4960336 788856..790268 1 NC_009257.1 dihydrolipoamide dehydrogenase 790268 lpdA 4960336 lpdA Francisella tularensis subsp. tularensis WY96-3418 dihydrolipoamide dehydrogenase YP_001121802.1 788856 D 418136 CDS YP_001121803.1 134301835 4960377 join(790622..790951,790951..791502) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 791502 4960377 FTW_0811 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121803.1 790622 D 418136 CDS YP_001121804.1 134301836 4960395 791719..791907 1 NC_009257.1 hypothetical protein 791907 4960395 FTW_0813 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121804.1 791719 D 418136 CDS YP_001121805.1 134301837 4959720 793733..794287 1 NC_009257.1 fatty acid hydroxylase 794287 4959720 FTW_0815 Francisella tularensis subsp. tularensis WY96-3418 fatty acid hydroxylase YP_001121805.1 793733 D 418136 CDS YP_001121806.1 134301838 4960343 794362..796515 1 NC_009257.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 796515 rlmL 4960343 rlmL Francisella tularensis subsp. tularensis WY96-3418 23S rRNA m(2)G2445 methyltransferase YP_001121806.1 794362 D 418136 CDS YP_001121807.1 134301839 4960042 796641..797015 1 NC_009257.1 hypothetical protein 797015 4960042 FTW_0817 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121807.1 796641 D 418136 CDS YP_001121808.1 134301840 4960294 797020..797961 1 NC_009257.1 methionyl-tRNA formyltransferase 797961 fmt 4960294 fmt Francisella tularensis subsp. tularensis WY96-3418 methionyl-tRNA formyltransferase YP_001121808.1 797020 D 418136 CDS YP_001121809.1 134301841 4960018 797965..798939 1 NC_009257.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 798939 gshB 4960018 gshB Francisella tularensis subsp. tularensis WY96-3418 glutathione synthetase YP_001121809.1 797965 D 418136 CDS YP_001121810.1 134301842 4959991 798929..800224 1 NC_009257.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 800224 hemL 4959991 hemL Francisella tularensis subsp. tularensis WY96-3418 glutamate-1-semialdehyde aminotransferase YP_001121810.1 798929 D 418136 CDS YP_001121811.1 134301843 4959968 complement(800245..801912) 1 NC_009257.1 glycosyl hydrolase family protein 801912 4959968 FTW_0821 Francisella tularensis subsp. tularensis WY96-3418 glycosyl hydrolase family protein YP_001121811.1 800245 R 418136 CDS YP_001121812.1 134301844 4959657 804939..805790 1 NC_009257.1 ROK family protein 805790 4959657 FTW_0827 Francisella tularensis subsp. tularensis WY96-3418 ROK family protein YP_001121812.1 804939 D 418136 CDS YP_001121813.1 134301845 4960476 805813..806775 1 NC_009257.1 biotin--acetyl-CoA-carboxylase ligase 806775 birA 4960476 birA Francisella tularensis subsp. tularensis WY96-3418 biotin--acetyl-CoA-carboxylase ligase YP_001121813.1 805813 D 418136 CDS YP_001121814.1 134302630 4959577 complement(806718..807395) 1 NC_009257.1 inferred from blast alignment with NRAA database; dethiobiotin synthetase 807395 4959577 FTW_2081 Francisella tularensis subsp. tularensis WY96-3418 dethiobiotin synthetase YP_001121814.1 806718 R 418136 CDS YP_001121815.1 134301846 4959292 complement(807399..808136) 1 NC_009257.1 biotin synthesis protein BioC 808136 4959292 FTW_0829 Francisella tularensis subsp. tularensis WY96-3418 biotin synthesis protein BioC YP_001121815.1 807399 R 418136 CDS YP_001121816.1 134301847 4959559 complement(808114..809241) 1 NC_009257.1 8-amino-7-oxononanoate synthase 809241 4959559 FTW_0830 Francisella tularensis subsp. tularensis WY96-3418 8-amino-7-oxononanoate synthase YP_001121816.1 808114 R 418136 CDS YP_001121817.1 134301848 4959198 complement(809235..810176) 1 NC_009257.1 biotin synthase 810176 bioB 4959198 bioB Francisella tularensis subsp. tularensis WY96-3418 biotin synthase YP_001121817.1 809235 R 418136 CDS YP_001121818.1 134301849 4959417 810267..811553 1 NC_009257.1 class III aminotransferase 811553 4959417 FTW_0832 Francisella tularensis subsp. tularensis WY96-3418 class III aminotransferase YP_001121818.1 810267 D 418136 CDS YP_001121819.1 134301850 4960513 complement(811663..812607) 1 NC_009257.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 812607 add 4960513 add Francisella tularensis subsp. tularensis WY96-3418 adenosine deaminase YP_001121819.1 811663 R 418136 CDS YP_001121820.1 134301851 4960385 complement(812755..813255) 1 NC_009257.1 hypothetical protein 813255 4960385 FTW_0834 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121820.1 812755 R 418136 CDS YP_001121821.1 134301852 4960471 complement(813271..814191) 1 NC_009257.1 alpha/beta hydrolase fold protein 814191 4960471 FTW_0835 Francisella tularensis subsp. tularensis WY96-3418 alpha/beta hydrolase fold protein YP_001121821.1 813271 R 418136 CDS YP_001121822.1 134301853 4959415 complement(814204..815469) 1 NC_009257.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 815469 4959415 FTW_0836 Francisella tularensis subsp. tularensis WY96-3418 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_001121822.1 814204 R 418136 CDS YP_001121823.1 134301854 4959447 complement(815471..815824) 1 NC_009257.1 dihydroneopterin aldolase 815824 4959447 FTW_0837 Francisella tularensis subsp. tularensis WY96-3418 dihydroneopterin aldolase YP_001121823.1 815471 R 418136 CDS YP_001121824.1 134301855 4960266 815906..817276 1 NC_009257.1 AMP-binding protein 817276 4960266 FTW_0838 Francisella tularensis subsp. tularensis WY96-3418 AMP-binding protein YP_001121824.1 815906 D 418136 CDS YP_001121825.1 134301856 4960046 817269..819032 1 NC_009257.1 chorismate binding family protein/para-amino benzoate synthase component I 819032 4960046 FTW_0839 Francisella tularensis subsp. tularensis WY96-3418 chorismate binding family protein/para-amino benzoate synthase component I YP_001121825.1 817269 D 418136 CDS YP_001121826.1 134301857 4960045 819034..819588 1 NC_009257.1 anthranilate synthase component II 819588 4960045 FTW_0840 Francisella tularensis subsp. tularensis WY96-3418 anthranilate synthase component II YP_001121826.1 819034 D 418136 CDS YP_001121827.1 134301858 4959673 complement(821968..822888) 1 NC_009257.1 carbon-nitrogen family hydrolase 822888 4959673 FTW_0845 Francisella tularensis subsp. tularensis WY96-3418 carbon-nitrogen family hydrolase YP_001121827.1 821968 R 418136 CDS YP_001121828.1 134301859 4959158 complement(822966..823391) 1 NC_009257.1 hypothetical protein 823391 4959158 FTW_0846 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121828.1 822966 R 418136 CDS YP_001121829.1 134301860 4960467 complement(824238..824855) 1 NC_009257.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 824855 folE 4960467 folE Francisella tularensis subsp. tularensis WY96-3418 GTP cyclohydrolase I YP_001121829.1 824238 R 418136 CDS YP_001121830.1 134301861 4959278 824985..826310 1 NC_009257.1 DEAD/DEAH box helicase 826310 4959278 FTW_0850 Francisella tularensis subsp. tularensis WY96-3418 DEAD/DEAH box helicase YP_001121830.1 824985 D 418136 CDS YP_001121831.1 134301862 4958822 complement(826307..827848) 1 NC_009257.1 amino acid/peptide transporter (peptide:H+ symporter) 827848 4958822 FTW_0851 Francisella tularensis subsp. tularensis WY96-3418 amino acid/peptide transporter (peptide:H+ symporter) YP_001121831.1 826307 R 418136 CDS YP_001121832.1 134301863 4958691 complement(827986..828306) 1 NC_009257.1 hypothetical protein 828306 4958691 FTW_0852 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121832.1 827986 R 418136 CDS YP_001121833.1 134301864 4958714 complement(828317..829678) 1 NC_009257.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 829678 gor 4958714 gor Francisella tularensis subsp. tularensis WY96-3418 glutathione reductase YP_001121833.1 828317 R 418136 CDS YP_001121834.1 134301865 4958896 complement(829716..830435) 1 NC_009257.1 hypothetical protein 830435 4958896 FTW_0854 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121834.1 829716 R 418136 CDS YP_001121835.1 134301866 4959100 complement(830941..831648) 1 NC_009257.1 short chain dehydrogenase 831648 4959100 FTW_0857 Francisella tularensis subsp. tularensis WY96-3418 short chain dehydrogenase YP_001121835.1 830941 R 418136 CDS YP_001121836.1 134301867 4959353 complement(831669..832457) 1 NC_009257.1 exodeoxyribonuclease III 832457 xthA 4959353 xthA Francisella tularensis subsp. tularensis WY96-3418 exodeoxyribonuclease III YP_001121836.1 831669 R 418136 CDS YP_001121837.1 134301868 4959257 832741..833724 1 NC_009257.1 succinylglutamate desuccinylase 833724 4959257 FTW_0859 Francisella tularensis subsp. tularensis WY96-3418 succinylglutamate desuccinylase YP_001121837.1 832741 D 418136 CDS YP_001121838.1 134301869 4958697 833732..834322 1 NC_009257.1 flavodoxin-like fold family protein 834322 4958697 FTW_0860 Francisella tularensis subsp. tularensis WY96-3418 flavodoxin-like fold family protein YP_001121838.1 833732 D 418136 CDS YP_001121839.1 134301870 4959169 834438..835100 1 NC_009257.1 DJ-1/PfpI family protein 835100 4959169 FTW_0861 Francisella tularensis subsp. tularensis WY96-3418 DJ-1/PfpI family protein YP_001121839.1 834438 D 418136 CDS YP_001121840.1 134301871 4958683 complement(835170..836282) 1 NC_009257.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 836282 aroG 4958683 aroG Francisella tularensis subsp. tularensis WY96-3418 phospho-2-dehydro-3-deoxyheptonate aldolase YP_001121840.1 835170 R 418136 CDS YP_001121841.1 134301872 4958914 complement(836314..837690) 1 NC_009257.1 signal recognition particle protein 837690 ffh 4958914 ffh Francisella tularensis subsp. tularensis WY96-3418 signal recognition particle protein YP_001121841.1 836314 R 418136 CDS YP_001121842.1 134301873 4959297 complement(837771..838037) 1 NC_009257.1 hypothetical protein 838037 4959297 FTW_0864 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121842.1 837771 R 418136 CDS YP_001121843.1 134301874 4959641 839034..839252 1 NC_009257.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 839252 infA 4959641 infA Francisella tularensis subsp. tularensis WY96-3418 translation initiation factor IF-1 YP_001121843.1 839034 D 418136 CDS YP_001121844.1 134301875 4959819 complement(840214..841635) 1 NC_009257.1 amino acid antiporter 841635 4959819 FTW_0870 Francisella tularensis subsp. tularensis WY96-3418 amino acid antiporter YP_001121844.1 840214 R 418136 CDS YP_001121845.1 134301876 4960297 complement(841694..843067) 1 NC_009257.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 843067 trkA 4960297 trkA Francisella tularensis subsp. tularensis WY96-3418 potassium transporter peripheral membrane protein YP_001121845.1 841694 R 418136 CDS YP_001121846.1 134301877 4960305 843220..843630 1 NC_009257.1 rrf2 family transcriptional regulator 843630 4960305 FTW_0872 Francisella tularensis subsp. tularensis WY96-3418 rrf2 family transcriptional regulator YP_001121846.1 843220 D 418136 CDS YP_001121847.1 134301878 4959982 843637..845082 1 NC_009257.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 845082 sufB 4959982 sufB Francisella tularensis subsp. tularensis WY96-3418 cysteine desulfurase activator complex subunit SufB YP_001121847.1 843637 D 418136 CDS YP_001121848.1 134301879 4960529 845121..845870 1 NC_009257.1 FeS assembly ATPase SufC 845870 sufC 4960529 sufC Francisella tularensis subsp. tularensis WY96-3418 FeS assembly ATPase SufC YP_001121848.1 845121 D 418136 CDS YP_001121849.1 134301880 4959345 845883..847028 1 NC_009257.1 sufB/SufD domain-containing protein 847028 4959345 FTW_0875 Francisella tularensis subsp. tularensis WY96-3418 sufB/SufD domain-containing protein YP_001121849.1 845883 D 418136 CDS YP_001121850.1 134301881 4958681 848687..849013 1 NC_009257.1 thioredoxin 849013 trx2 4958681 trx2 Francisella tularensis subsp. tularensis WY96-3418 thioredoxin YP_001121850.1 848687 D 418136 CDS YP_001121851.1 134301882 4960530 849266..849427 1 NC_009257.1 hypothetical protein 849427 4960530 FTW_0881 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121851.1 849266 D 418136 CDS YP_001121852.1 134301883 4959131 complement(849410..849703) 1 NC_009257.1 hypothetical protein 849703 4959131 FTW_0882 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121852.1 849410 R 418136 CDS YP_001121853.1 134301884 4958810 complement(849707..850312) 1 NC_009257.1 hypothetical protein 850312 4958810 FTW_0883 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121853.1 849707 R 418136 CDS YP_001121854.1 134301885 4958786 complement(850364..851731) 1 NC_009257.1 amino-acid permease family protein 851731 4958786 FTW_0884 Francisella tularensis subsp. tularensis WY96-3418 amino-acid permease family protein YP_001121854.1 850364 R 418136 CDS YP_001121855.1 134301886 4959018 851965..853206 1 NC_009257.1 hypothetical protein 853206 4959018 FTW_0885 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121855.1 851965 D 418136 CDS YP_001121856.1 134301887 4958889 853539..854669 1 NC_009257.1 hypothetical protein 854669 4958889 FTW_0886 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121856.1 853539 D 418136 CDS YP_001121857.1 134301888 4960122 855607..855753 1 NC_009257.1 hypothetical protein 855753 4960122 FTW_0888 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121857.1 855607 D 418136 CDS YP_001121858.1 134301889 4959029 855729..856100 1 NC_009257.1 hypothetical protein 856100 4959029 FTW_0889 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121858.1 855729 D 418136 CDS YP_001121859.1 134301890 4960534 856734..857318 1 NC_009257.1 hypothetical protein 857318 4960534 FTW_0891 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121859.1 856734 D 418136 CDS YP_001121860.1 134301891 4960535 857320..857730 1 NC_009257.1 hypothetical protein 857730 4960535 FTW_0892 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121860.1 857320 D 418136 CDS YP_001121861.1 134301892 4960303 857823..858020 1 NC_009257.1 lipoprotein 858020 4960303 FTW_0893 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001121861.1 857823 D 418136 CDS YP_001121862.1 134301893 4960337 858143..858400 1 NC_009257.1 hypothetical protein 858400 4960337 FTW_0894 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121862.1 858143 D 418136 CDS YP_001121863.1 134301894 4960419 860540..862981 1 NC_009257.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 862981 leuS 4960419 leuS Francisella tularensis subsp. tularensis WY96-3418 leucyl-tRNA synthetase YP_001121863.1 860540 D 418136 CDS YP_001121864.1 134301895 4960376 862992..863564 1 NC_009257.1 rare lipoprotein B related protein 863564 4960376 FTW_0898 Francisella tularensis subsp. tularensis WY96-3418 rare lipoprotein B related protein YP_001121864.1 862992 D 418136 CDS YP_001121865.1 134301896 4960360 863625..864815 1 NC_009257.1 mechanosensitive ion channel family protein 864815 4960360 FTW_0899 Francisella tularensis subsp. tularensis WY96-3418 mechanosensitive ion channel family protein YP_001121865.1 863625 D 418136 CDS YP_001121866.1 134301897 4960319 complement(864822..865388) 1 NC_009257.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 865388 dcd 4960319 dcd Francisella tularensis subsp. tularensis WY96-3418 deoxycytidine triphosphate deaminase YP_001121866.1 864822 R 418136 CDS YP_001121867.1 134301898 4960194 complement(865400..866260) 1 NC_009257.1 putative MRP protein 866260 4960194 FTW_0901 Francisella tularensis subsp. tularensis WY96-3418 putative MRP protein YP_001121867.1 865400 R 418136 CDS YP_001121868.1 134301899 4960007 866334..867566 1 NC_009257.1 major facilitator transporter 867566 4960007 FTW_0902 Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001121868.1 866334 D 418136 CDS YP_001121869.1 134301900 4959895 869136..870566 1 NC_009257.1 putative phospholipase D/cardiolipin synthetase 870566 4959895 FTW_0905 Francisella tularensis subsp. tularensis WY96-3418 putative phospholipase D/cardiolipin synthetase YP_001121869.1 869136 D 418136 CDS YP_001121870.1 134301901 4959833 870732..871721 1 NC_009257.1 hypothetical protein 871721 4959833 FTW_0906 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121870.1 870732 D 418136 CDS YP_001121871.1 134301902 4959675 complement(871743..872489) 1 NC_009257.1 zinc/iron ABC transporter permease 872489 4959675 FTW_0907 Francisella tularensis subsp. tularensis WY96-3418 zinc/iron ABC transporter permease YP_001121871.1 871743 R 418136 CDS YP_001121872.1 134301903 4959607 complement(872492..873709) 1 NC_009257.1 putative cobalamin synthesis protein/P47K family protein 873709 4959607 FTW_0908 Francisella tularensis subsp. tularensis WY96-3418 putative cobalamin synthesis protein/P47K family protein YP_001121872.1 872492 R 418136 CDS YP_001121873.1 134301904 4959558 873857..874282 1 NC_009257.1 putative Fe2+/Zn2+ uptake regulation protein 874282 4959558 FTW_0909 Francisella tularensis subsp. tularensis WY96-3418 putative Fe2+/Zn2+ uptake regulation protein YP_001121873.1 873857 D 418136 CDS YP_001121874.1 134301905 4959489 complement(874325..876697) 1 NC_009257.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 876697 pheT 4959489 pheT Francisella tularensis subsp. tularensis WY96-3418 phenylalanyl-tRNA synthetase subunit beta YP_001121874.1 874325 R 418136 CDS YP_001121875.1 134301906 4958959 complement(876718..877731) 1 NC_009257.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 877731 pheS 4958959 pheS Francisella tularensis subsp. tularensis WY96-3418 phenylalanyl-tRNA synthetase subunit alpha YP_001121875.1 876718 R 418136 CDS YP_001121876.1 134301907 4959400 complement(877817..878707) 1 NC_009257.1 hypothetical protein 878707 4959400 FTW_0912 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121876.1 877817 R 418136 CDS YP_001121877.1 134301908 4959357 complement(878732..880207) 1 NC_009257.1 amino acid transporter 880207 4959357 FTW_0913 Francisella tularensis subsp. tularensis WY96-3418 amino acid transporter YP_001121877.1 878732 R 418136 CDS YP_001121878.1 134301909 4959701 880520..881659 1 NC_009257.1 hypothetical protein 881659 4959701 FTW_0914 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121878.1 880520 D 418136 CDS YP_001121879.1 134301910 4959774 complement(881644..882591) 1 NC_009257.1 hypothetical protein 882591 4959774 FTW_0915 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121879.1 881644 R 418136 CDS YP_001121880.1 134301911 4959440 882719..883255 1 NC_009257.1 hypothetical protein 883255 4959440 FTW_0916 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121880.1 882719 D 418136 CDS YP_001121881.1 134301912 4960318 883270..883473 1 NC_009257.1 hypothetical protein 883473 4960318 FTW_0917 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121881.1 883270 D 418136 CDS YP_001121882.1 134301913 4960465 complement(884760..885806) 1 NC_009257.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 885806 ruvB 4960465 ruvB Francisella tularensis subsp. tularensis WY96-3418 Holliday junction DNA helicase RuvB YP_001121882.1 884760 R 418136 CDS YP_001121883.1 134301914 4960526 complement(885870..886595) 1 NC_009257.1 short chain dehydrogenase family protein 886595 4960526 FTW_0921 Francisella tularensis subsp. tularensis WY96-3418 short chain dehydrogenase family protein YP_001121883.1 885870 R 418136 CDS YP_001121884.1 134301915 4958858 886713..887303 1 NC_009257.1 hypothetical protein 887303 4958858 FTW_0922 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121884.1 886713 D 418136 CDS YP_001121885.1 134301916 4958815 complement(887313..887942) 1 NC_009257.1 putative GDSL-like lipase/acylhydrolase 887942 4958815 FTW_0923 Francisella tularensis subsp. tularensis WY96-3418 putative GDSL-like lipase/acylhydrolase YP_001121885.1 887313 R 418136 CDS YP_001121886.1 134301917 4958951 complement(887964..888299) 1 NC_009257.1 hypothetical protein 888299 4958951 FTW_0924 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121886.1 887964 R 418136 CDS YP_001121887.1 134301918 4958824 complement(888315..890162) 1 NC_009257.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 890162 dxs 4958824 dxs Francisella tularensis subsp. tularensis WY96-3418 1-deoxy-D-xylulose-5-phosphate synthase YP_001121887.1 888315 R 418136 CDS YP_001121888.1 134301919 4959027 complement(890244..891794) 1 NC_009257.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 891794 guaA 4959027 guaA Francisella tularensis subsp. tularensis WY96-3418 GMP synthase YP_001121888.1 890244 R 418136 CDS YP_001121889.1 134301920 4959407 complement(891882..893426) 1 NC_009257.1 amino acid permease 893426 4959407 FTW_0927 Francisella tularensis subsp. tularensis WY96-3418 amino acid permease YP_001121889.1 891882 R 418136 CDS YP_001121890.1 134301921 4958904 complement(893482..894258) 1 NC_009257.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 894258 truA 4958904 truA Francisella tularensis subsp. tularensis WY96-3418 tRNA pseudouridine synthase A YP_001121890.1 893482 R 418136 CDS YP_001121891.1 134301922 4959008 complement(894261..896096) 1 NC_009257.1 phosphorylase family 2 protein 896096 4959008 FTW_0929 Francisella tularensis subsp. tularensis WY96-3418 phosphorylase family 2 protein YP_001121891.1 894261 R 418136 CDS YP_001121892.1 134301923 4959147 complement(896109..896702) 1 NC_009257.1 fumarylacetoacetate hydrolase family protein 896702 4959147 FTW_0930 Francisella tularensis subsp. tularensis WY96-3418 fumarylacetoacetate hydrolase family protein YP_001121892.1 896109 R 418136 CDS YP_001121893.1 134301924 4958898 complement(896751..897482) 1 NC_009257.1 ABC transporter ATP-binding protein 897482 4958898 FTW_0931 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter ATP-binding protein YP_001121893.1 896751 R 418136 CDS YP_001121894.1 134301925 4959426 complement(897556..898389) 1 NC_009257.1 hypothetical protein 898389 4959426 FTW_0932 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121894.1 897556 R 418136 CDS YP_001121895.1 134301926 4959053 complement(898376..899002) 1 NC_009257.1 hypothetical protein 899002 4959053 FTW_0933 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121895.1 898376 R 418136 CDS YP_001121896.1 134301927 4958903 complement(899010..899558) 1 NC_009257.1 YrbI family phosphatase 899558 4958903 FTW_0934 Francisella tularensis subsp. tularensis WY96-3418 YrbI family phosphatase YP_001121896.1 899010 R 418136 CDS YP_001121897.1 134301928 4959106 complement(899649..900170) 1 NC_009257.1 inorganic pyrophosphatase 900170 ppa 4959106 ppa Francisella tularensis subsp. tularensis WY96-3418 inorganic pyrophosphatase YP_001121897.1 899649 R 418136 CDS YP_001121898.1 134301929 4958942 900328..901662 1 NC_009257.1 D-alanyl-D-alanine carboxypeptidase 901662 4958942 FTW_0936 Francisella tularensis subsp. tularensis WY96-3418 D-alanyl-D-alanine carboxypeptidase YP_001121898.1 900328 D 418136 CDS YP_001121899.1 134301930 4959070 901695..901979 1 NC_009257.1 hypothetical protein 901979 4959070 FTW_0937 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121899.1 901695 D 418136 CDS YP_001121900.1 134301931 4959060 901989..902609 1 NC_009257.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 902609 lipB 4959060 lipB Francisella tularensis subsp. tularensis WY96-3418 lipoate-protein ligase B YP_001121900.1 901989 D 418136 CDS YP_001121901.1 134301932 4958905 complement(906681..907943) 1 NC_009257.1 NADH dehydrogenase 907943 4958905 FTW_0943 Francisella tularensis subsp. tularensis WY96-3418 NADH dehydrogenase YP_001121901.1 906681 R 418136 CDS YP_001121902.1 134301933 4959211 complement(908050..909783) 1 NC_009257.1 RNA polymerase sigma-70 factor 909783 rpoD 4959211 rpoD Francisella tularensis subsp. tularensis WY96-3418 RNA polymerase sigma-70 factor YP_001121902.1 908050 R 418136 CDS YP_001121903.1 134301934 4960450 complement(909803..911620) 1 NC_009257.1 DNA primase 911620 dnaG 4960450 dnaG Francisella tularensis subsp. tularensis WY96-3418 DNA primase YP_001121903.1 909803 R 418136 CDS YP_001121904.1 134301935 4959196 complement(911641..912087) 1 NC_009257.1 GatB/YqeY domain-containing protein 912087 4959196 FTW_0946 Francisella tularensis subsp. tularensis WY96-3418 GatB/YqeY domain-containing protein YP_001121904.1 911641 R 418136 CDS YP_001121905.1 134301936 4959432 complement(912148..912345) 1 NC_009257.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 912345 rpsU 4959432 rpsU Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S21 YP_001121905.1 912148 R 418136 CDS YP_001121906.1 134301937 4959507 912601..914004 1 NC_009257.1 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 914004 dacB1 4959507 dacB1 Francisella tularensis subsp. tularensis WY96-3418 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase YP_001121906.1 912601 D 418136 CDS YP_001121907.1 134301938 4959289 914005..914616 1 NC_009257.1 lipoprotein 914616 4959289 FTW_0949 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001121907.1 914005 D 418136 CDS YP_001121908.1 134301939 4958988 914632..915048 1 NC_009257.1 hypothetical protein 915048 4958988 FTW_0950 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121908.1 914632 D 418136 CDS YP_001121909.1 134301940 4959571 915041..915844 1 NC_009257.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 915844 4959571 FTW_0951 Francisella tularensis subsp. tularensis WY96-3418 C32 tRNA thiolase YP_001121909.1 915041 D 418136 CDS YP_001121910.1 134301941 4959580 915857..916669 1 NC_009257.1 peptidyl-prolyl cis-trans isomerase family protein 916669 4959580 FTW_0952 Francisella tularensis subsp. tularensis WY96-3418 peptidyl-prolyl cis-trans isomerase family protein YP_001121910.1 915857 D 418136 CDS YP_001121911.1 134301942 4959524 complement(916687..917664) 1 NC_009257.1 polyprenyl synthetase family protein 917664 4959524 FTW_0953 Francisella tularensis subsp. tularensis WY96-3418 polyprenyl synthetase family protein YP_001121911.1 916687 R 418136 CDS YP_001121912.1 134301943 4959634 complement(917754..918185) 1 NC_009257.1 hypothetical protein 918185 4959634 FTW_0954 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121912.1 917754 R 418136 CDS YP_001121913.1 134301944 4959614 complement(918266..918889) 1 NC_009257.1 hypothetical protein 918889 4959614 FTW_0955 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121913.1 918266 R 418136 CDS YP_001121914.1 134301945 4959640 complement(919562..919924) 1 NC_009257.1 hypothetical protein 919924 4959640 FTW_0956 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121914.1 919562 R 418136 CDS YP_001121915.1 134301946 4959613 complement(919976..920542) 1 NC_009257.1 hypothetical protein 920542 4959613 FTW_0957 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121915.1 919976 R 418136 CDS YP_001121916.1 134301947 4959651 complement(920967..921536) 1 NC_009257.1 adenylylsulfate kinase 921536 cysC 4959651 cysC Francisella tularensis subsp. tularensis WY96-3418 adenylylsulfate kinase YP_001121916.1 920967 R 418136 CDS YP_001121917.1 134301948 4959678 complement(921587..922999) 1 NC_009257.1 sulfate adenylyltransferase subunit 1 922999 cysN 4959678 cysN Francisella tularensis subsp. tularensis WY96-3418 sulfate adenylyltransferase subunit 1 YP_001121917.1 921587 R 418136 CDS YP_001121918.1 134301949 4959716 complement(924062..924256) 1 NC_009257.1 hypothetical protein 924256 4959716 FTW_0960 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121918.1 924062 R 418136 CDS YP_001121919.1 134301950 4959666 complement(924529..924666) 1 NC_009257.1 hypothetical protein 924666 4959666 FTW_0961 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121919.1 924529 R 418136 CDS YP_001121920.1 134301951 4959715 complement(924696..924839) 1 NC_009257.1 hypothetical protein 924839 4959715 FTW_0962 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121920.1 924696 R 418136 CDS YP_001121921.1 134301952 4959744 complement(926044..926484) 1 NC_009257.1 acetyltransferase 926484 4959744 FTW_0964 Francisella tularensis subsp. tularensis WY96-3418 acetyltransferase YP_001121921.1 926044 R 418136 CDS YP_001121922.1 134301953 4960453 complement(926462..926887) 1 NC_009257.1 hypothetical protein 926887 4960453 FTW_0965 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121922.1 926462 R 418136 CDS YP_001121923.1 134301954 4959796 complement(926887..927702) 1 NC_009257.1 putative RNA pseudouridine synthase B 927702 4959796 FTW_0966 Francisella tularensis subsp. tularensis WY96-3418 putative RNA pseudouridine synthase B YP_001121923.1 926887 R 418136 CDS YP_001121924.1 134301955 4959825 complement(927695..928537) 1 NC_009257.1 hypothetical protein 928537 4959825 FTW_0967 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121924.1 927695 R 418136 CDS YP_001121925.1 134301956 4959792 complement(928590..929702) 1 NC_009257.1 radical SAM protein 929702 4959792 FTW_0968 Francisella tularensis subsp. tularensis WY96-3418 radical SAM protein YP_001121925.1 928590 R 418136 CDS YP_001121926.1 134301957 4959837 complement(929733..931127) 1 NC_009257.1 replicative DNA helicase 931127 dnaB 4959837 dnaB Francisella tularensis subsp. tularensis WY96-3418 replicative DNA helicase YP_001121926.1 929733 R 418136 CDS YP_001121927.1 134301958 4959821 complement(931218..931673) 1 NC_009257.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 931673 rplI 4959821 rplI Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L9 YP_001121927.1 931218 R 418136 CDS YP_001121928.1 134301959 4959852 complement(931692..931910) 1 NC_009257.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 931910 rpsR 4959852 rpsR Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S18 YP_001121928.1 931692 R 418136 CDS YP_001121929.1 134301960 4959824 complement(931926..932261) 1 NC_009257.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 932261 rpsF 4959824 rpsF Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S6 YP_001121929.1 931926 R 418136 CDS YP_001121930.1 134301961 4959860 932322..932597 1 NC_009257.1 hypothetical protein 932597 4959860 FTW_0973 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121930.1 932322 D 418136 CDS YP_001121931.1 134301962 4959849 932938..933864 1 NC_009257.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 933864 hemF 4959849 hemF Francisella tularensis subsp. tularensis WY96-3418 coproporphyrinogen III oxidase YP_001121931.1 932938 D 418136 CDS YP_001121932.1 134301963 4959881 complement(join(934922..935473,935473..935802)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 935802 4959881 FTW_0977 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121932.1 934922 R 418136 CDS YP_001121933.1 134301964 4960015 936122..937174 1 NC_009257.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 937174 serC 4960015 serC Francisella tularensis subsp. tularensis WY96-3418 phosphoserine aminotransferase YP_001121933.1 936122 D 418136 CDS YP_001121934.1 134301965 4960041 937161..937826 1 NC_009257.1 cytidylate kinase 937826 cmk 4960041 cmk Francisella tularensis subsp. tularensis WY96-3418 cytidylate kinase YP_001121934.1 937161 D 418136 CDS YP_001121935.1 134301966 4960515 complement(937843..938454) 1 NC_009257.1 short chain dehydrogenase 938454 4960515 FTW_0982 Francisella tularensis subsp. tularensis WY96-3418 short chain dehydrogenase YP_001121935.1 937843 R 418136 CDS YP_001121936.1 134301967 4960076 complement(938457..938981) 1 NC_009257.1 AhpC/TSA family protein 938981 4960076 FTW_0983 Francisella tularensis subsp. tularensis WY96-3418 AhpC/TSA family protein YP_001121936.1 938457 R 418136 CDS YP_001121937.1 134301968 4960016 939079..939948 1 NC_009257.1 LysR family transcriptional regulator 939948 4960016 FTW_0984 Francisella tularensis subsp. tularensis WY96-3418 LysR family transcriptional regulator YP_001121937.1 939079 D 418136 CDS YP_001121938.1 134301969 4958801 complement(939951..940682) 1 NC_009257.1 hypothetical protein 940682 4958801 FTW_0985 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121938.1 939951 R 418136 CDS YP_001121939.1 134301970 4959213 complement(940696..940968) 1 NC_009257.1 hypothetical protein 940968 4959213 FTW_0986 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121939.1 940696 R 418136 CDS YP_001121940.1 134301971 4958870 complement(941052..941831) 1 NC_009257.1 hypothetical protein 941831 4958870 FTW_0987 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121940.1 941052 R 418136 CDS YP_001121941.1 134301972 4958838 complement(941836..943332) 1 NC_009257.1 NAD-dependent aldehyde dehydrogenase 943332 4958838 FTW_0988 Francisella tularensis subsp. tularensis WY96-3418 NAD-dependent aldehyde dehydrogenase YP_001121941.1 941836 R 418136 CDS YP_001121942.1 134301973 4958753 complement(944762..946198) 1 NC_009257.1 hypothetical protein 946198 4958753 FTW_0991 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121942.1 944762 R 418136 CDS YP_001121943.1 134301974 4960069 complement(946158..946631) 1 NC_009257.1 D-alanyl-D-alanine carboxypeptidase 946631 4960069 FTW_0992 Francisella tularensis subsp. tularensis WY96-3418 D-alanyl-D-alanine carboxypeptidase YP_001121943.1 946158 R 418136 CDS YP_001121944.1 134301975 4959192 complement(946625..947317) 1 NC_009257.1 DNA polymerase III subunit epsilon 947317 dnaQ 4959192 dnaQ Francisella tularensis subsp. tularensis WY96-3418 DNA polymerase III subunit epsilon YP_001121944.1 946625 R 418136 CDS YP_001121945.1 134301976 4959253 complement(947371..947904) 1 NC_009257.1 hypothetical protein 947904 4959253 FTW_0994 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121945.1 947371 R 418136 CDS YP_001121946.1 134301977 4959095 complement(948257..948868) 1 NC_009257.1 hypothetical protein 948868 4959095 FTW_0995 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121946.1 948257 R 418136 CDS YP_001121947.1 134301978 4958806 complement(948872..949087) 1 NC_009257.1 hypothetical protein 949087 4958806 FTW_0996 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121947.1 948872 R 418136 CDS YP_001121948.1 134301979 4958923 complement(949093..949425) 1 NC_009257.1 alkylphosphonate utilization protein PhnA 949425 phnA 4958923 phnA Francisella tularensis subsp. tularensis WY96-3418 alkylphosphonate utilization protein PhnA YP_001121948.1 949093 R 418136 CDS YP_001121949.1 134301980 4958764 complement(949531..950907) 1 NC_009257.1 hypothetical protein 950907 4958764 FTW_0998 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121949.1 949531 R 418136 CDS YP_001121950.1 134301981 4958821 951035..951148 1 NC_009257.1 hypothetical protein 951148 4958821 FTW_0999 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121950.1 951035 D 418136 CDS YP_001121951.1 134301982 4958802 951628..952227 1 NC_009257.1 haloacid dehalogenase-like hydrolase 952227 4958802 FTW_1001 Francisella tularensis subsp. tularensis WY96-3418 haloacid dehalogenase-like hydrolase YP_001121951.1 951628 D 418136 CDS YP_001121952.1 134301983 4958948 952282..953772 1 NC_009257.1 hypothetical protein 953772 4958948 FTW_1002 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121952.1 952282 D 418136 CDS YP_001121953.1 134301984 4959022 953776..954321 1 NC_009257.1 HesA/MoeB/ThiF family protein 954321 4959022 FTW_1003 Francisella tularensis subsp. tularensis WY96-3418 HesA/MoeB/ThiF family protein YP_001121953.1 953776 D 418136 CDS YP_001121954.1 134301985 4959098 954597..955166 1 NC_009257.1 transglycosylase 955166 4959098 FTW_1004 Francisella tularensis subsp. tularensis WY96-3418 transglycosylase YP_001121954.1 954597 D 418136 CDS YP_001121955.1 134301986 4958757 complement(955175..955810) 1 NC_009257.1 ubiquinone biosynthesis protein 955810 4958757 FTW_1005 Francisella tularensis subsp. tularensis WY96-3418 ubiquinone biosynthesis protein YP_001121955.1 955175 R 418136 CDS YP_001121956.1 134301987 4958944 complement(955826..956338) 1 NC_009257.1 hypothetical protein 956338 4958944 FTW_1006 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121956.1 955826 R 418136 CDS YP_001121957.1 134301988 4959049 956489..957448 1 NC_009257.1 Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 957448 mdh 4959049 mdh Francisella tularensis subsp. tularensis WY96-3418 malate dehydrogenase YP_001121957.1 956489 D 418136 CDS YP_001121958.1 134301989 4959026 957652..959424 1 NC_009257.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 959424 nrdA 4959026 nrdA Francisella tularensis subsp. tularensis WY96-3418 ribonucleotide-diphosphate reductase subunit alpha YP_001121958.1 957652 D 418136 CDS YP_001121959.1 134301990 4959125 959428..959688 1 NC_009257.1 glutaredoxin 959688 grxA 4959125 grxA Francisella tularensis subsp. tularensis WY96-3418 glutaredoxin YP_001121959.1 959428 D 418136 CDS YP_001121960.1 134301991 4958873 959695..960927 1 NC_009257.1 bifunctional gluaredoxin/ribonucleoside-diphosphate reductase subunit beta 960927 4958873 FTW_1010 Francisella tularensis subsp. tularensis WY96-3418 bifunctional gluaredoxin/ribonucleoside-diphosphate reductase subunit beta YP_001121960.1 959695 D 418136 CDS YP_001121961.1 134301992 4958784 complement(960930..962816) 1 NC_009257.1 ABC transporters, ATP-binding protein 962816 4958784 FTW_1011 Francisella tularensis subsp. tularensis WY96-3418 ABC transporters, ATP-binding protein YP_001121961.1 960930 R 418136 CDS YP_001121962.1 134301993 4958928 962927..963529 1 NC_009257.1 DJ-1/PfpI family protein 963529 4958928 FTW_1012 Francisella tularensis subsp. tularensis WY96-3418 DJ-1/PfpI family protein YP_001121962.1 962927 D 418136 CDS YP_001121963.1 134301994 4959446 complement(963915..964040) 1 NC_009257.1 hypothetical protein 964040 4959446 FTW_1014 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121963.1 963915 R 418136 CDS YP_001121964.1 134301995 4958915 complement(964607..966013) 1 NC_009257.1 hypothetical protein 966013 4958915 FTW_1016 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121964.1 964607 R 418136 CDS YP_001121965.1 134301996 4958829 complement(966019..966675) 1 NC_009257.1 hypothetical protein 966675 4958829 FTW_1017 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121965.1 966019 R 418136 CDS YP_001121966.1 134301997 4959370 complement(966722..967108) 1 NC_009257.1 hypothetical protein 967108 4959370 FTW_1018 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121966.1 966722 R 418136 CDS YP_001121967.1 134301999 4958992 complement(968701..969972) 1 NC_009257.1 putative N-6 DNA methylase 969972 4958992 FTW_1023 Francisella tularensis subsp. tularensis WY96-3418 putative N-6 DNA methylase YP_001121967.1 968701 R 418136 CDS YP_001121968.1 134301998 4959068 969995..970165 1 NC_009257.1 hypothetical protein 970165 4959068 FTW_1022 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121968.1 969995 D 418136 CDS YP_001121969.1 134302000 4958946 complement(970204..970797) 1 NC_009257.1 hypothetical protein 970797 4958946 FTW_1024 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121969.1 970204 R 418136 CDS YP_001121970.1 134302001 4958813 complement(971027..972010) 1 NC_009257.1 tRNA-dihydrouridine synthase 972010 4958813 FTW_1025 Francisella tularensis subsp. tularensis WY96-3418 tRNA-dihydrouridine synthase YP_001121970.1 971027 R 418136 CDS YP_001121971.1 134302002 4958823 complement(972000..972845) 1 NC_009257.1 50S ribosomal protein L11 methyltransferase 972845 prmA 4958823 prmA Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L11 methyltransferase YP_001121971.1 972000 R 418136 CDS YP_001121972.1 134302003 4959047 complement(977181..977357) 1 NC_009257.1 hypothetical protein 977357 4959047 FTW_1031 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121972.1 977181 R 418136 CDS YP_001121973.1 134302004 4958740 complement(977380..978522) 1 NC_009257.1 L-lactate dehydrogenase 978522 4958740 FTW_1032 Francisella tularensis subsp. tularensis WY96-3418 L-lactate dehydrogenase YP_001121973.1 977380 R 418136 CDS YP_001121974.1 134302005 4959078 join(978617..978946,978946..979497) 1 NC_009257.1 Transposase, member of the IS630 Tc-1 mariner family. This gene contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' which permits frameshifting to produce a single ORF; programmed frameshift; transposase ISFtu1 979497 4959078 FTW_1034 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001121974.1 978617 D 418136 CDS YP_001121975.1 134302006 4959110 complement(979900..981120) 1 NC_009257.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 981120 tyrS 4959110 tyrS Francisella tularensis subsp. tularensis WY96-3418 tyrosyl-tRNA synthetase YP_001121975.1 979900 R 418136 CDS YP_001121976.1 134302007 4960140 981204..982106 1 NC_009257.1 lipoate-protein ligase A 982106 4960140 FTW_1036 Francisella tularensis subsp. tularensis WY96-3418 lipoate-protein ligase A YP_001121976.1 981204 D 418136 CDS YP_001121977.1 134302008 4959011 complement(982110..982859) 1 NC_009257.1 hypothetical protein 982859 4959011 FTW_1037 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121977.1 982110 R 418136 CDS YP_001121978.1 134302009 4959044 983051..983602 1 NC_009257.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 983602 hslV 4959044 hslV Francisella tularensis subsp. tularensis WY96-3418 ATP-dependent protease peptidase subunit YP_001121978.1 983051 D 418136 CDS YP_001121979.1 134302010 4959388 983610..984977 1 NC_009257.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 984977 hslU 4959388 hslU Francisella tularensis subsp. tularensis WY96-3418 ATP-dependent protease ATP-binding subunit HslU YP_001121979.1 983610 D 418136 CDS YP_001121980.1 134302011 4958996 985075..986532 1 NC_009257.1 amino acid transporter 986532 4958996 FTW_1040 Francisella tularensis subsp. tularensis WY96-3418 amino acid transporter YP_001121980.1 985075 D 418136 CDS YP_001121981.1 134302012 4958977 987862..989262 1 NC_009257.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 989262 sthA 4958977 sthA Francisella tularensis subsp. tularensis WY96-3418 soluble pyridine nucleotide transhydrogenase YP_001121981.1 987862 D 418136 CDS YP_001121982.1 134302013 4958799 989293..990084 1 NC_009257.1 prepilin peptidase family protein 990084 4958799 FTW_1045 Francisella tularensis subsp. tularensis WY96-3418 prepilin peptidase family protein YP_001121982.1 989293 D 418136 CDS YP_001121983.1 134302014 4959069 990124..990969 1 NC_009257.1 hypothetical protein 990969 4959069 FTW_1046 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121983.1 990124 D 418136 CDS YP_001121984.1 134302015 4960454 990978..991862 1 NC_009257.1 beta-lactamase 991862 blaA 4960454 blaA Francisella tularensis subsp. tularensis WY96-3418 beta-lactamase YP_001121984.1 990978 D 418136 CDS YP_001121985.1 134302016 4960165 991855..992430 1 NC_009257.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 992430 pth 4960165 pth Francisella tularensis subsp. tularensis WY96-3418 peptidyl-tRNA hydrolase YP_001121985.1 991855 D 418136 CDS YP_001121986.1 134302017 4960183 992449..993540 1 NC_009257.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 993540 ychF 4960183 ychF Francisella tularensis subsp. tularensis WY96-3418 GTP-dependent nucleic acid-binding protein EngD YP_001121986.1 992449 D 418136 CDS YP_001121987.1 134302018 4960193 993555..993722 1 NC_009257.1 hypothetical protein 993722 4960193 FTW_1050 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121987.1 993555 D 418136 CDS YP_001121988.1 134302019 4959863 994439..995215 1 NC_009257.1 UbiE/COQ5 family methlytransferase 995215 4959863 FTW_1051 Francisella tularensis subsp. tularensis WY96-3418 UbiE/COQ5 family methlytransferase YP_001121988.1 994439 D 418136 CDS YP_001121989.1 134302020 4960201 complement(995420..996679) 1 NC_009257.1 hypothetical protein 996679 4960201 FTW_1052 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121989.1 995420 R 418136 CDS YP_001121990.1 134302021 4960221 complement(996775..997065) 1 NC_009257.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 997065 rplY 4960221 rplY Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L25 YP_001121990.1 996775 R 418136 CDS YP_001121991.1 134302022 4960249 complement(997165..998133) 1 NC_009257.1 ribose-phosphate pyrophosphokinase 998133 prsA 4960249 prsA Francisella tularensis subsp. tularensis WY96-3418 ribose-phosphate pyrophosphokinase YP_001121991.1 997165 R 418136 CDS YP_001121992.1 134302023 4960255 998344..999351 1 NC_009257.1 succinylglutamate desuccinylase 999351 4960255 FTW_1055 Francisella tularensis subsp. tularensis WY96-3418 succinylglutamate desuccinylase YP_001121992.1 998344 D 418136 CDS YP_001121993.1 134302024 4960313 999344..1000627 1 NC_009257.1 major facilitator superfamily transporter 1000627 4960313 FTW_1056 Francisella tularensis subsp. tularensis WY96-3418 major facilitator superfamily transporter YP_001121993.1 999344 D 418136 CDS YP_001121994.1 134302025 4960308 complement(1000634..1001914) 1 NC_009257.1 major facilitator superfamily transporter 1001914 4960308 FTW_1057 Francisella tularensis subsp. tularensis WY96-3418 major facilitator superfamily transporter YP_001121994.1 1000634 R 418136 CDS YP_001121995.1 134302026 4959788 1002227..1002691 1 NC_009257.1 hypothetical protein 1002691 4959788 FTW_1058 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121995.1 1002227 D 418136 CDS YP_001121996.1 134302027 4960323 complement(1003023..1004198) 1 NC_009257.1 monovalent cation/proton antiporter-2 (CPA2) family monovalent cation/proton antiporter 1004198 4960323 FTW_1059 Francisella tularensis subsp. tularensis WY96-3418 monovalent cation/proton antiporter-2 (CPA2) family monovalent cation/proton antiporter YP_001121996.1 1003023 R 418136 CDS YP_001121997.1 134302028 4960347 complement(1004296..1004928) 1 NC_009257.1 nicotinamide mononucleotide transporter 1004928 pnuC1 4960347 pnuC1 Francisella tularensis subsp. tularensis WY96-3418 nicotinamide mononucleotide transporter YP_001121997.1 1004296 R 418136 CDS YP_001121998.1 134302029 4958741 complement(1004928..1005431) 1 NC_009257.1 hypothetical protein 1005431 4958741 FTW_1061 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001121998.1 1004928 R 418136 CDS YP_001121999.1 134302030 4960370 1005559..1006140 1 NC_009257.1 3-methyladenine DNA glycosylase 1006140 4960370 FTW_1062 Francisella tularensis subsp. tularensis WY96-3418 3-methyladenine DNA glycosylase YP_001121999.1 1005559 D 418136 CDS YP_001122000.1 134302031 4960403 1006231..1006929 1 NC_009257.1 aldolase and adducin class II family protein 1006929 4960403 FTW_1063 Francisella tularensis subsp. tularensis WY96-3418 aldolase and adducin class II family protein YP_001122000.1 1006231 D 418136 CDS YP_001122001.1 134302032 4960405 1006944..1008080 1 NC_009257.1 catalyzes the formation of histamine from L-histidine; histidine decarboxylase 1008080 4960405 FTW_1064 Francisella tularensis subsp. tularensis WY96-3418 histidine decarboxylase YP_001122001.1 1006944 D 418136 CDS YP_001122002.1 134302033 4960425 complement(1008067..1008879) 1 NC_009257.1 hypothetical protein 1008879 4960425 FTW_1065 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122002.1 1008067 R 418136 CDS YP_001122003.1 134302034 4960445 1009043..1009375 1 NC_009257.1 hypothetical protein 1009375 4960445 FTW_1066 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122003.1 1009043 D 418136 CDS YP_001122004.1 134302035 4959015 complement(1009783..1009902) 1 NC_009257.1 hypothetical protein 1009902 4959015 FTW_1067 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122004.1 1009783 R 418136 CDS YP_001122005.1 134302036 4959017 complement(1009856..1010443) 1 NC_009257.1 hypothetical protein 1010443 4959017 FTW_1068 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122005.1 1009856 R 418136 CDS YP_001122006.1 134302037 4959102 complement(1010492..1011907) 1 NC_009257.1 RmuC domain-containing DNA recombination protein 1011907 4959102 FTW_1069 Francisella tularensis subsp. tularensis WY96-3418 RmuC domain-containing DNA recombination protein YP_001122006.1 1010492 R 418136 CDS YP_001122007.1 134302038 4959013 complement(1011933..1012583) 1 NC_009257.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1012583 ruvA 4959013 ruvA Francisella tularensis subsp. tularensis WY96-3418 Holliday junction DNA helicase RuvA YP_001122007.1 1011933 R 418136 CDS YP_001122008.1 134302039 4958880 complement(1012596..1013789) 1 NC_009257.1 major facilitator superfamily transporter 1013789 4958880 FTW_1071 Francisella tularensis subsp. tularensis WY96-3418 major facilitator superfamily transporter YP_001122008.1 1012596 R 418136 CDS YP_001122009.1 134302040 4958814 complement(1013871..1014386) 1 NC_009257.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1014386 ruvC 4958814 ruvC Francisella tularensis subsp. tularensis WY96-3418 Holliday junction resolvase YP_001122009.1 1013871 R 418136 CDS YP_001122010.1 134302041 4960357 complement(1014483..1015229) 1 NC_009257.1 hypothetical protein 1015229 4960357 FTW_1073 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122010.1 1014483 R 418136 CDS YP_001122011.1 134302042 4959092 complement(1015245..1015904) 1 NC_009257.1 isoprenoid biosynthesis protein with amidotransferase-like domain 1015904 4959092 FTW_1074 Francisella tularensis subsp. tularensis WY96-3418 isoprenoid biosynthesis protein with amidotransferase-like domain YP_001122011.1 1015245 R 418136 CDS YP_001122012.1 134302043 4960225 complement(1015934..1016917) 1 NC_009257.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1016917 lipA 4960225 lipA Francisella tularensis subsp. tularensis WY96-3418 lipoyl synthase YP_001122012.1 1015934 R 418136 CDS YP_001122013.1 134302044 4959880 complement(1017626..1019173) 1 NC_009257.1 amino acid/peptide transporter (peptide:H+ symporter) 1019173 4959880 FTW_1078 Francisella tularensis subsp. tularensis WY96-3418 amino acid/peptide transporter (peptide:H+ symporter) YP_001122013.1 1017626 R 418136 CDS YP_001122014.1 134302045 4959677 1019256..1019900 1 NC_009257.1 cofactor involved in the reduction of disulfides; glutaredoxin 1019900 4959677 FTW_1079 Francisella tularensis subsp. tularensis WY96-3418 glutaredoxin YP_001122014.1 1019256 D 418136 CDS YP_001122015.1 134302046 4960484 1019902..1020531 1 NC_009257.1 RnfABCDGE type electron transport complex subunit B 1020531 4960484 FTW_1080 Francisella tularensis subsp. tularensis WY96-3418 RnfABCDGE type electron transport complex subunit B YP_001122015.1 1019902 D 418136 CDS YP_001122016.1 134302047 4960468 1020524..1021162 1 NC_009257.1 endonuclease III 1021162 nth 4960468 nth Francisella tularensis subsp. tularensis WY96-3418 endonuclease III YP_001122016.1 1020524 D 418136 CDS YP_001122017.1 134302048 4960512 1021159..1021590 1 NC_009257.1 hypothetical protein 1021590 4960512 FTW_1082 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122017.1 1021159 D 418136 CDS YP_001122018.1 134302049 4960458 1021590..1022849 1 NC_009257.1 hypothetical protein 1022849 4960458 FTW_1083 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122018.1 1021590 D 418136 CDS YP_001122019.1 134302050 4960520 1022965..1023651 1 NC_009257.1 hypothetical protein 1023651 4960520 FTW_1084 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122019.1 1022965 D 418136 CDS YP_001122020.1 134302051 4960516 1023696..1027121 1 NC_009257.1 transcription-repair coupling factor 1027121 mfd 4960516 mfd Francisella tularensis subsp. tularensis WY96-3418 transcription-repair coupling factor YP_001122020.1 1023696 D 418136 CDS YP_001122021.1 134302052 4958907 complement(1027244..1028287) 1 NC_009257.1 ketol-acid reductoisomerase 1028287 ilvC 4958907 ilvC Francisella tularensis subsp. tularensis WY96-3418 ketol-acid reductoisomerase YP_001122021.1 1027244 R 418136 CDS YP_001122022.1 134302053 4958711 complement(1028315..1028632) 1 NC_009257.1 ACT domain-containing protein/acetolactate synthase small subunit 1028632 4958711 FTW_1087 Francisella tularensis subsp. tularensis WY96-3418 ACT domain-containing protein/acetolactate synthase small subunit YP_001122022.1 1028315 R 418136 CDS YP_001122023.1 134302054 4958703 complement(1030469..1032151) 1 NC_009257.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1032151 ilvD 4958703 ilvD Francisella tularensis subsp. tularensis WY96-3418 dihydroxy-acid dehydratase YP_001122023.1 1030469 R 418136 CDS YP_001122024.1 134302055 4958692 complement(1032327..1032728) 1 NC_009257.1 hypothetical protein 1032728 4958692 FTW_1091 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122024.1 1032327 R 418136 CDS YP_001122025.1 134302056 4958684 complement(1032785..1033786) 1 NC_009257.1 putative threonine synthase 1033786 4958684 FTW_1092 Francisella tularensis subsp. tularensis WY96-3418 putative threonine synthase YP_001122025.1 1032785 R 418136 CDS YP_001122026.1 134302057 4960368 complement(1034103..1034696) 1 NC_009257.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1034696 engB 4960368 engB Francisella tularensis subsp. tularensis WY96-3418 ribosome biogenesis GTP-binding protein YsxC YP_001122026.1 1034103 R 418136 CDS YP_001122027.1 134302058 4960364 complement(1034693..1035178) 1 NC_009257.1 low molecular weight (LMW) phosphotyrosine protein phosphatase 1035178 4960364 FTW_1094 Francisella tularensis subsp. tularensis WY96-3418 low molecular weight (LMW) phosphotyrosine protein phosphatase YP_001122027.1 1034693 R 418136 CDS YP_001122028.1 134302059 4960391 complement(1035179..1036105) 1 NC_009257.1 HflC protein 1036105 hflC 4960391 hflC Francisella tularensis subsp. tularensis WY96-3418 HflC protein YP_001122028.1 1035179 R 418136 CDS YP_001122029.1 134302060 4960401 complement(1036107..1037174) 1 NC_009257.1 HflK protein 1037174 hflK 4960401 hflK Francisella tularensis subsp. tularensis WY96-3418 HflK protein YP_001122029.1 1036107 R 418136 CDS YP_001122030.1 134302061 4960404 1037359..1038537 1 NC_009257.1 hypothetical protein 1038537 4960404 FTW_1097 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122030.1 1037359 D 418136 CDS YP_001122031.1 134302062 4960424 complement(1038548..1039855) 1 NC_009257.1 protease, GTP-binding subunit 1039855 4960424 FTW_1098 Francisella tularensis subsp. tularensis WY96-3418 protease, GTP-binding subunit YP_001122031.1 1038548 R 418136 CDS YP_001122032.1 134302063 4960429 complement(1039907..1040236) 1 NC_009257.1 host factor I for bacteriophage Q beta replication 1040236 hfq 4960429 hfq Francisella tularensis subsp. tularensis WY96-3418 host factor I for bacteriophage Q beta replication YP_001122032.1 1039907 R 418136 CDS YP_001122033.1 134302064 4960433 complement(1040347..1041273) 1 NC_009257.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1041273 miaA 4960433 miaA Francisella tularensis subsp. tularensis WY96-3418 tRNA delta(2)-isopentenylpyrophosphate transferase YP_001122033.1 1040347 R 418136 CDS YP_001122034.1 134302065 4959936 complement(1041274..1042704) 1 NC_009257.1 hypothetical protein 1042704 4959936 FTW_1101 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122034.1 1041274 R 418136 CDS YP_001122035.1 134302066 4960420 complement(1042817..1043089) 1 NC_009257.1 DNA-binding protein HU-beta 1043089 hup 4960420 hup Francisella tularensis subsp. tularensis WY96-3418 DNA-binding protein HU-beta YP_001122035.1 1042817 R 418136 CDS YP_001122036.1 134302067 4959972 complement(1043176..1045500) 1 NC_009257.1 DNA-binding, ATP-dependent protease La 1045500 lon 4959972 lon Francisella tularensis subsp. tularensis WY96-3418 DNA-binding, ATP-dependent protease La YP_001122036.1 1043176 R 418136 CDS YP_001122037.1 134302068 4959574 complement(1045525..1046778) 1 NC_009257.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1046778 clpX 4959574 clpX Francisella tularensis subsp. tularensis WY96-3418 ATP-dependent protease ATP-binding subunit ClpX YP_001122037.1 1045525 R 418136 CDS YP_001122038.1 134302069 4959262 complement(1046802..1047407) 1 NC_009257.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1047407 clpP 4959262 clpP Francisella tularensis subsp. tularensis WY96-3418 ATP-dependent Clp protease proteolytic subunit YP_001122038.1 1046802 R 418136 CDS YP_001122039.1 134302070 4959501 complement(1047433..1048749) 1 NC_009257.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1048749 tig 4959501 tig Francisella tularensis subsp. tularensis WY96-3418 trigger factor YP_001122039.1 1047433 R 418136 CDS YP_001122040.1 134302071 4960356 complement(1049411..1050004) 1 NC_009257.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1050004 tdk 4960356 tdk Francisella tularensis subsp. tularensis WY96-3418 thymidine kinase YP_001122040.1 1049411 R 418136 CDS YP_001122041.1 134302072 4960342 complement(1050020..1050739) 1 NC_009257.1 acid phosphatase 1050739 4960342 FTW_1108 Francisella tularensis subsp. tularensis WY96-3418 acid phosphatase YP_001122041.1 1050020 R 418136 CDS YP_001122042.1 134302073 4959450 complement(1050772..1051407) 1 NC_009257.1 o-methyltransferase family protein 1051407 4959450 FTW_1109 Francisella tularensis subsp. tularensis WY96-3418 o-methyltransferase family protein YP_001122042.1 1050772 R 418136 CDS YP_001122043.1 134302074 4960286 1051669..1052997 1 NC_009257.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1052997 miaB 4960286 miaB Francisella tularensis subsp. tularensis WY96-3418 (dimethylallyl)adenosine tRNA methylthiotransferase YP_001122043.1 1051669 D 418136 CDS YP_001122044.1 134302075 4960245 1053046..1053984 1 NC_009257.1 phoH family protein 1053984 4960245 FTW_1111 Francisella tularensis subsp. tularensis WY96-3418 phoH family protein YP_001122044.1 1053046 D 418136 CDS YP_001122045.1 134302076 4960187 1053977..1054465 1 NC_009257.1 hypothetical protein 1054465 4960187 FTW_1112 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122045.1 1053977 D 418136 CDS YP_001122046.1 134302077 4960114 1054455..1055297 1 NC_009257.1 hypothetical protein 1055297 4960114 FTW_1113 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122046.1 1054455 D 418136 CDS YP_001122047.1 134302078 4959924 1055297..1056787 1 NC_009257.1 apolipoprotein N-acyltransferase 1056787 lnt 4959924 lnt Francisella tularensis subsp. tularensis WY96-3418 apolipoprotein N-acyltransferase YP_001122047.1 1055297 D 418136 CDS YP_001122048.1 134302079 4959874 1057033..1057452 1 NC_009257.1 hypothetical protein 1057452 4959874 FTW_1115 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122048.1 1057033 D 418136 CDS YP_001122049.1 134302080 4959798 complement(1057604..1058587) 1 NC_009257.1 hypothetical protein 1058587 4959798 FTW_1116 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122049.1 1057604 R 418136 CDS YP_001122050.1 134302081 4959769 1059023..1059886 1 NC_009257.1 putative beta-lactamase 1059886 4959769 FTW_1117 Francisella tularensis subsp. tularensis WY96-3418 putative beta-lactamase YP_001122050.1 1059023 D 418136 CDS YP_001122051.1 134302082 4959621 complement(1059877..1060941) 1 NC_009257.1 DNA/RNA endonuclease 1060941 4959621 FTW_1118 Francisella tularensis subsp. tularensis WY96-3418 DNA/RNA endonuclease YP_001122051.1 1059877 R 418136 CDS YP_001122052.1 134302083 4959667 complement(1061039..1062832) 1 NC_009257.1 M24 family peptidase 1062832 4959667 FTW_1119 Francisella tularensis subsp. tularensis WY96-3418 M24 family peptidase YP_001122052.1 1061039 R 418136 CDS YP_001122053.1 134302084 4959556 complement(1062851..1063558) 1 NC_009257.1 hypothetical protein 1063558 4959556 FTW_1120 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122053.1 1062851 R 418136 CDS YP_001122054.1 134302085 4959091 complement(1063573..1064778) 1 NC_009257.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1064778 ispG 4959091 ispG Francisella tularensis subsp. tularensis WY96-3418 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_001122054.1 1063573 R 418136 CDS YP_001122055.1 134302086 4959074 complement(1066919..1067098) 1 NC_009257.1 hypothetical protein 1067098 4959074 FTW_1126 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122055.1 1066919 R 418136 CDS YP_001122056.1 134302087 4959503 1067721..1069136 1 NC_009257.1 hypothetical protein 1069136 4959503 FTW_1127 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122056.1 1067721 D 418136 CDS YP_001122057.1 134302088 4959492 complement(1069740..1069859) 1 NC_009257.1 hypothetical protein 1069859 4959492 FTW_1128 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122057.1 1069740 R 418136 CDS YP_001122058.1 134302089 4958826 complement(1070014..1071417) 1 NC_009257.1 major facilitator superfamily sugar transporter 1071417 4958826 FTW_1129 Francisella tularensis subsp. tularensis WY96-3418 major facilitator superfamily sugar transporter YP_001122058.1 1070014 R 418136 CDS YP_001122059.1 134302090 4958881 complement(1071442..1072470) 1 NC_009257.1 SIS domain-containing protein 1072470 4958881 FTW_1130 Francisella tularensis subsp. tularensis WY96-3418 SIS domain-containing protein YP_001122059.1 1071442 R 418136 CDS YP_001122060.1 134302091 4958680 1072672..1073946 1 NC_009257.1 DAACS family dicarboxylate/amino acid:sodium or proton symporter 1073946 4958680 FTW_1131 Francisella tularensis subsp. tularensis WY96-3418 DAACS family dicarboxylate/amino acid:sodium or proton symporter YP_001122060.1 1072672 D 418136 CDS YP_001122061.1 134302092 4958690 complement(1073978..1075372) 1 NC_009257.1 hypothetical protein 1075372 4958690 FTW_1132 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122061.1 1073978 R 418136 CDS YP_001122062.1 134302093 4958687 1075484..1076101 1 NC_009257.1 hypothetical protein 1076101 4958687 FTW_1133 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122062.1 1075484 D 418136 CDS YP_001122063.1 134302094 4959487 1076188..1076358 1 NC_009257.1 rubredoxin 1076358 rubA 4959487 rubA Francisella tularensis subsp. tularensis WY96-3418 rubredoxin YP_001122063.1 1076188 D 418136 CDS YP_001122064.1 134302095 4958746 1076367..1077239 1 NC_009257.1 hypothetical protein 1077239 4958746 FTW_1135 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122064.1 1076367 D 418136 CDS YP_001122065.1 134302096 4959112 1077303..1077908 1 NC_009257.1 hypothetical protein 1077908 4959112 FTW_1136 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122065.1 1077303 D 418136 CDS YP_001122066.1 134302097 4958957 complement(1078195..1078881) 1 NC_009257.1 carbonic anhydrase 1078881 cynT 4958957 cynT Francisella tularensis subsp. tularensis WY96-3418 carbonic anhydrase YP_001122066.1 1078195 R 418136 CDS YP_001122067.1 134302098 4958772 complement(1078952..1079989) 1 NC_009257.1 L-asparaginase 1079989 ansA 4958772 ansA Francisella tularensis subsp. tularensis WY96-3418 L-asparaginase YP_001122067.1 1078952 R 418136 CDS YP_001122068.1 134302099 4958830 complement(1079991..1080449) 1 NC_009257.1 RNase H 1080449 rnhA 4958830 rnhA Francisella tularensis subsp. tularensis WY96-3418 RNase H YP_001122068.1 1079991 R 418136 CDS YP_001122069.1 134302100 4958847 complement(1080424..1081014) 1 NC_009257.1 hypothetical protein 1081014 4958847 FTW_1140 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122069.1 1080424 R 418136 CDS YP_001122070.1 134302101 4958812 complement(1081017..1082294) 1 NC_009257.1 3-phosphoshikimate 1-carboxyvinyltransferase 1082294 aroA 4958812 aroA Francisella tularensis subsp. tularensis WY96-3418 3-phosphoshikimate 1-carboxyvinyltransferase YP_001122070.1 1081017 R 418136 CDS YP_001122071.1 134302102 4959089 complement(1083248..1084126) 1 NC_009257.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 1084126 rpoH 4959089 rpoH Francisella tularensis subsp. tularensis WY96-3418 RNA polymerase factor sigma-32 YP_001122071.1 1083248 R 418136 CDS YP_001122072.1 134302103 4959496 complement(1084150..1084680) 1 NC_009257.1 hypothetical protein 1084680 4959496 FTW_1145 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122072.1 1084150 R 418136 CDS YP_001122073.1 134302104 4959469 complement(1084712..1085656) 1 NC_009257.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1085656 secF 4959469 secF Francisella tularensis subsp. tularensis WY96-3418 preprotein translocase subunit SecF YP_001122073.1 1084712 R 418136 CDS YP_001122074.1 134302105 4959499 complement(1085675..1087612) 1 NC_009257.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1087612 secD 4959499 secD Francisella tularensis subsp. tularensis WY96-3418 preprotein translocase subunit SecD YP_001122074.1 1085675 R 418136 CDS YP_001122075.1 134302106 4959315 complement(1087669..1088025) 1 NC_009257.1 preprotein translocase subunit YajC 1088025 yajC 4959315 yajC Francisella tularensis subsp. tularensis WY96-3418 preprotein translocase subunit YajC YP_001122075.1 1087669 R 418136 CDS YP_001122076.1 134302107 4959312 complement(1088288..1088461) 1 NC_009257.1 hypothetical protein 1088461 4959312 FTW_1149 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122076.1 1088288 R 418136 CDS YP_001122077.1 134302108 4959414 complement(1088580..1089152) 1 NC_009257.1 isochorismatase hydrolase family protein 1089152 4959414 FTW_1150 Francisella tularensis subsp. tularensis WY96-3418 isochorismatase hydrolase family protein YP_001122077.1 1088580 R 418136 CDS YP_001122078.1 134302109 4958817 complement(1089164..1090039) 1 NC_009257.1 integral membrane protein 1090039 4958817 FTW_1151 Francisella tularensis subsp. tularensis WY96-3418 integral membrane protein YP_001122078.1 1089164 R 418136 CDS YP_001122079.1 134302110 4959020 1090144..1091019 1 NC_009257.1 LysR family transcriptional regulator 1091019 4959020 FTW_1152 Francisella tularensis subsp. tularensis WY96-3418 LysR family transcriptional regulator YP_001122079.1 1090144 D 418136 CDS YP_001122080.1 134302111 4958767 complement(1091026..1092129) 1 NC_009257.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1092129 tgt 4958767 tgt Francisella tularensis subsp. tularensis WY96-3418 queuine tRNA-ribosyltransferase YP_001122080.1 1091026 R 418136 CDS YP_001122081.1 134302112 4959054 1092434..1092655 1 NC_009257.1 IS1016 family transposase 1092655 4959054 FTW_1154 Francisella tularensis subsp. tularensis WY96-3418 IS1016 family transposase YP_001122081.1 1092434 D 418136 CDS YP_001122082.1 134302113 4958762 complement(1093111..1093506) 1 NC_009257.1 hypothetical protein 1093506 4958762 FTW_1155 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122082.1 1093111 R 418136 CDS YP_001122083.1 134302114 4959477 1094203..1094778 1 NC_009257.1 hypothetical protein 1094778 4959477 FTW_1156 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122083.1 1094203 D 418136 CDS YP_001122084.1 134302115 4959002 1094741..1095817 1 NC_009257.1 ABC transporter ATP-binding protein 1095817 4959002 FTW_1157 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter ATP-binding protein YP_001122084.1 1094741 D 418136 CDS YP_001122085.1 134302116 4959474 1095795..1097267 1 NC_009257.1 ABC transporter permease 1097267 4959474 FTW_1158 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter permease YP_001122085.1 1095795 D 418136 CDS YP_001122086.1 134302117 4959494 1097338..1098549 1 NC_009257.1 tryptophan/tyrosine permease family protein 1098549 4959494 FTW_1159 Francisella tularensis subsp. tularensis WY96-3418 tryptophan/tyrosine permease family protein YP_001122086.1 1097338 D 418136 CDS YP_001122087.1 134302118 4959476 1098615..1099373 1 NC_009257.1 rhodanese-like domain-containing protein 1099373 4959476 FTW_1160 Francisella tularensis subsp. tularensis WY96-3418 rhodanese-like domain-containing protein YP_001122087.1 1098615 D 418136 CDS YP_001122088.1 134302119 4959471 1099386..1099865 1 NC_009257.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1099865 ispF 4959471 ispF Francisella tularensis subsp. tularensis WY96-3418 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_001122088.1 1099386 D 418136 CDS YP_001122089.1 134302120 4959458 complement(1099870..1101555) 1 NC_009257.1 glutamate ligase domain-containing protein 1101555 4959458 FTW_1162 Francisella tularensis subsp. tularensis WY96-3418 glutamate ligase domain-containing protein YP_001122089.1 1099870 R 418136 CDS YP_001122090.1 134302121 4959383 complement(1101581..1104403) 1 NC_009257.1 catalyze the formation of cyanophycin which may act to store excess nitrogen; cyanophycin synthetase 1104403 cphA 4959383 cphA Francisella tularensis subsp. tularensis WY96-3418 cyanophycin synthetase YP_001122090.1 1101581 R 418136 CDS YP_001122091.1 134302122 4959506 1104527..1105270 1 NC_009257.1 molybdopterin binding domain-containing protein 1105270 4959506 FTW_1164 Francisella tularensis subsp. tularensis WY96-3418 molybdopterin binding domain-containing protein YP_001122091.1 1104527 D 418136 CDS YP_001122092.1 134302123 4959382 complement(1105259..1106011) 1 NC_009257.1 glycerophosphoryl diester phosphodiesterase 1106011 4959382 FTW_1165 Francisella tularensis subsp. tularensis WY96-3418 glycerophosphoryl diester phosphodiesterase YP_001122092.1 1105259 R 418136 CDS YP_001122093.1 134302124 4959598 1106169..1107947 1 NC_009257.1 type IV-A pilus assembly ATPase/type II secretion system protein 1107947 pilB 4959598 pilB Francisella tularensis subsp. tularensis WY96-3418 type IV-A pilus assembly ATPase/type II secretion system protein YP_001122093.1 1106169 D 418136 CDS YP_001122094.1 134302125 4959561 1107962..1109191 1 NC_009257.1 Type IV pili polytopic inner membrane protein 1109191 4959561 FTW_1167 Francisella tularensis subsp. tularensis WY96-3418 Type IV pili polytopic inner membrane protein YP_001122094.1 1107962 D 418136 CDS YP_001122095.1 134302126 4959648 complement(1110436..1110771) 1 NC_009257.1 hypothetical protein 1110771 4959648 FTW_1170 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122095.1 1110436 R 418136 CDS YP_001122096.1 134302127 4959740 complement(1110788..1111039) 1 NC_009257.1 hypothetical protein 1111039 4959740 FTW_1171 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122096.1 1110788 R 418136 CDS YP_001122097.1 134302128 4959684 1111182..1112183 1 NC_009257.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1112183 hemH 4959684 hemH Francisella tularensis subsp. tularensis WY96-3418 ferrochelatase YP_001122097.1 1111182 D 418136 CDS YP_001122098.1 134302129 4959750 1112168..1113562 1 NC_009257.1 deoxyribodipyrimidine photolyase 1113562 phrB1 4959750 phrB1 Francisella tularensis subsp. tularensis WY96-3418 deoxyribodipyrimidine photolyase YP_001122098.1 1112168 D 418136 CDS YP_001122099.1 134302130 4959773 complement(1113657..1113779) 1 NC_009257.1 hypothetical protein 1113779 4959773 FTW_1174 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122099.1 1113657 R 418136 CDS YP_001122100.1 134302131 4959795 1114399..1114596 1 NC_009257.1 hypothetical protein 1114596 4959795 FTW_1175 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122100.1 1114399 D 418136 CDS YP_001122101.1 134302132 4959888 complement(join(1114754..1115305,1115305..1115634)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1115634 4959888 FTW_1177 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122101.1 1114754 R 418136 CDS YP_001122102.1 134302133 4959957 1115972..1116217 1 NC_009257.1 hypothetical protein 1116217 4959957 FTW_1180 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122102.1 1115972 D 418136 CDS YP_001122103.1 134302134 4959974 1117273..1117527 1 NC_009257.1 cation transport regulator 1117527 4959974 FTW_1183 Francisella tularensis subsp. tularensis WY96-3418 cation transport regulator YP_001122103.1 1117273 D 418136 CDS YP_001122104.1 134302135 4960100 complement(1118586..1119761) 1 NC_009257.1 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase 1119761 coaBC 4960100 coaBC Francisella tularensis subsp. tularensis WY96-3418 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase YP_001122104.1 1118586 R 418136 CDS YP_001122105.1 134302136 4960164 complement(1119774..1120958) 1 NC_009257.1 major facilitator family transporter 1120958 4960164 FTW_1187 Francisella tularensis subsp. tularensis WY96-3418 major facilitator family transporter YP_001122105.1 1119774 R 418136 CDS YP_001122106.1 134302137 4960107 complement(1121034..1122542) 1 NC_009257.1 amino acid transporter 1122542 4960107 FTW_1188 Francisella tularensis subsp. tularensis WY96-3418 amino acid transporter YP_001122106.1 1121034 R 418136 CDS YP_001122107.1 134302138 4960196 complement(1122702..1126766) 1 NC_009257.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1126766 putA 4960196 putA Francisella tularensis subsp. tularensis WY96-3418 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_001122107.1 1122702 R 418136 CDS YP_001122108.1 134302139 4959919 complement(1126783..1127070) 1 NC_009257.1 hypothetical protein 1127070 4959919 FTW_1190 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122108.1 1126783 R 418136 CDS YP_001122109.1 134302140 4960240 1127284..1127667 1 NC_009257.1 hypothetical protein 1127667 4960240 FTW_1191 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122109.1 1127284 D 418136 CDS YP_001122110.1 134302141 4959932 complement(1127839..1127958) 1 NC_009257.1 hypothetical protein 1127958 4959932 FTW_1192 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122110.1 1127839 R 418136 CDS YP_001122111.1 134302142 4959611 complement(1128016..1129095) 1 NC_009257.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1129095 aroB 4959611 aroB Francisella tularensis subsp. tularensis WY96-3418 3-dehydroquinate synthase YP_001122111.1 1128016 R 418136 CDS YP_001122112.1 134302143 4960263 complement(1129092..1129622) 1 NC_009257.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 1129622 aroK 4960263 aroK Francisella tularensis subsp. tularensis WY96-3418 shikimate kinase I YP_001122112.1 1129092 R 418136 CDS YP_001122113.1 134302144 4958796 complement(1129748..1131520) 1 NC_009257.1 type IV pilus secretin/type II and III secretion system protein 1131520 pilQ 4958796 pilQ Francisella tularensis subsp. tularensis WY96-3418 type IV pilus secretin/type II and III secretion system protein YP_001122113.1 1129748 R 418136 CDS YP_001122114.1 134302145 4960302 complement(1131533..1132123) 1 NC_009257.1 Type IV pilus biogenesis protein 1132123 4960302 FTW_1196 Francisella tularensis subsp. tularensis WY96-3418 Type IV pilus biogenesis protein YP_001122114.1 1131533 R 418136 CDS YP_001122115.1 134302146 4960332 complement(1132129..1132725) 1 NC_009257.1 hypothetical protein 1132725 4960332 FTW_1197 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122115.1 1132129 R 418136 CDS YP_001122116.1 134302147 4960306 complement(1132719..1133282) 1 NC_009257.1 Type IV pili associated protein 1133282 4960306 FTW_1198 Francisella tularensis subsp. tularensis WY96-3418 Type IV pili associated protein YP_001122116.1 1132719 R 418136 CDS YP_001122117.1 134302148 4960324 complement(1133284..1134288) 1 NC_009257.1 hypothetical protein 1134288 4960324 FTW_1199 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122117.1 1133284 R 418136 CDS YP_001122118.1 134302149 4959378 1134415..1135071 1 NC_009257.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1135071 adk 4959378 adk Francisella tularensis subsp. tularensis WY96-3418 adenylate kinase YP_001122118.1 1134415 D 418136 CDS YP_001122119.1 134302150 4960283 complement(1138411..1138827) 1 NC_009257.1 hypothetical protein 1138827 4960283 FTW_1206 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122119.1 1138411 R 418136 CDS YP_001122120.1 134302151 4959190 complement(1138842..1139735) 1 NC_009257.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1139735 era 4959190 era Francisella tularensis subsp. tularensis WY96-3418 GTP-binding protein Era YP_001122120.1 1138842 R 418136 CDS YP_001122121.1 134302152 4959371 complement(1139849..1141042) 1 NC_009257.1 aspartate aminotransferase 1141042 4959371 FTW_1208 Francisella tularensis subsp. tularensis WY96-3418 aspartate aminotransferase YP_001122121.1 1139849 R 418136 CDS YP_001122122.1 134302153 4959428 complement(1141052..1141858) 1 NC_009257.1 hypothetical protein 1141858 4959428 FTW_1209 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122122.1 1141052 R 418136 CDS YP_001122123.1 134302154 4959175 complement(1141862..1142500) 1 NC_009257.1 putative glycoprotease 1142500 4959175 FTW_1210 Francisella tularensis subsp. tularensis WY96-3418 putative glycoprotease YP_001122123.1 1141862 R 418136 CDS YP_001122124.1 134302155 4959232 complement(1142504..1143637) 1 NC_009257.1 N-acetylglucosamine-6-phosphate deacetylase 1143637 nagA 4959232 nagA Francisella tularensis subsp. tularensis WY96-3418 N-acetylglucosamine-6-phosphate deacetylase YP_001122124.1 1142504 R 418136 CDS YP_001122125.1 134302156 4959377 1143700..1144572 1 NC_009257.1 GTP-binding protein 1144572 4959377 FTW_1212 Francisella tularensis subsp. tularensis WY96-3418 GTP-binding protein YP_001122125.1 1143700 D 418136 CDS YP_001122126.1 134302157 4959040 1144639..1146384 1 NC_009257.1 hypothetical protein 1146384 4959040 FTW_1213 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122126.1 1144639 D 418136 CDS YP_001122127.1 134302158 4959441 complement(1146374..1147822) 1 NC_009257.1 N-6 DNA methylase family 1147822 4959441 FTW_1214 Francisella tularensis subsp. tularensis WY96-3418 N-6 DNA methylase family YP_001122127.1 1146374 R 418136 CDS YP_001122128.1 134302159 4959208 complement(1147827..1148258) 1 NC_009257.1 cold shock DNA -binding domain-containing protein 1148258 4959208 FTW_1215 Francisella tularensis subsp. tularensis WY96-3418 cold shock DNA -binding domain-containing protein YP_001122128.1 1147827 R 418136 CDS YP_001122129.1 134302160 4959191 complement(1149770..1149979) 1 NC_009257.1 hypothetical protein 1149979 4959191 FTW_1219 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122129.1 1149770 R 418136 CDS YP_001122130.1 134302161 4959397 complement(1150124..1150819) 1 NC_009257.1 hypothetical protein 1150819 4959397 FTW_1220 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122130.1 1150124 R 418136 CDS YP_001122131.1 134302162 4959379 1155278..1157095 1 NC_009257.1 GTP binding translational elongation factor Tu and G family protein 1157095 typA 4959379 typA Francisella tularensis subsp. tularensis WY96-3418 GTP binding translational elongation factor Tu and G family protein YP_001122131.1 1155278 D 418136 CDS YP_001122132.1 134302163 4959094 complement(1158038..1159843) 1 NC_009257.1 gamma-glutamyltransferase 1159843 ggt 4959094 ggt Francisella tularensis subsp. tularensis WY96-3418 gamma-glutamyltransferase YP_001122132.1 1158038 R 418136 CDS YP_001122133.1 134302164 4959584 complement(1160893..1162098) 1 NC_009257.1 FAD dependent oxidoreductase 1162098 4959584 FTW_1231 Francisella tularensis subsp. tularensis WY96-3418 FAD dependent oxidoreductase YP_001122133.1 1160893 R 418136 CDS YP_001122134.1 134302165 4959599 complement(1162140..1162445) 1 NC_009257.1 hypothetical protein 1162445 4959599 FTW_1232 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122134.1 1162140 R 418136 CDS YP_001122135.1 134302166 4959615 complement(1162445..1162876) 1 NC_009257.1 hypothetical protein 1162876 4959615 FTW_1233 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122135.1 1162445 R 418136 CDS YP_001122136.1 134302167 4959605 1162951..1163424 1 NC_009257.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1163424 smpB 4959605 smpB Francisella tularensis subsp. tularensis WY96-3418 SsrA-binding protein YP_001122136.1 1162951 D 418136 CDS YP_001122137.1 134302168 4959635 1163425..1164180 1 NC_009257.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1164180 4959635 FTW_1235 Francisella tularensis subsp. tularensis WY96-3418 C32 tRNA thiolase YP_001122137.1 1163425 D 418136 CDS YP_001122138.1 134302169 4959636 1164451..1165086 1 NC_009257.1 hypothetical protein 1165086 4959636 FTW_1236 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122138.1 1164451 D 418136 CDS YP_001122139.1 134302170 4959644 complement(1165326..1166597) 1 NC_009257.1 major facilitator superfamily transporter 1166597 4959644 FTW_1237 Francisella tularensis subsp. tularensis WY96-3418 major facilitator superfamily transporter YP_001122139.1 1165326 R 418136 CDS YP_001122140.1 134302171 4959671 complement(1166695..1166895) 1 NC_009257.1 hypothetical protein 1166895 4959671 FTW_1238 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122140.1 1166695 R 418136 CDS YP_001122141.1 134302172 4959704 complement(1166879..1168264) 1 NC_009257.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1168264 xseA 4959704 xseA Francisella tularensis subsp. tularensis WY96-3418 exodeoxyribonuclease VII large subunit YP_001122141.1 1166879 R 418136 CDS YP_001122142.1 134302173 4959724 1168417..1169577 1 NC_009257.1 aminoacylase 1169577 4959724 FTW_1240 Francisella tularensis subsp. tularensis WY96-3418 aminoacylase YP_001122142.1 1168417 D 418136 CDS YP_001122143.1 134302174 4959730 complement(1169627..1171378) 1 NC_009257.1 transglutaminase-like superfamily protein 1171378 4959730 FTW_1241 Francisella tularensis subsp. tularensis WY96-3418 transglutaminase-like superfamily protein YP_001122143.1 1169627 R 418136 CDS YP_001122144.1 134302175 4959747 complement(1171395..1172663) 1 NC_009257.1 hypothetical protein 1172663 4959747 FTW_1242 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122144.1 1171395 R 418136 CDS YP_001122145.1 134302176 4959771 complement(1172814..1174097) 1 NC_009257.1 major facilitator superfamily transporter 1174097 4959771 FTW_1243 Francisella tularensis subsp. tularensis WY96-3418 major facilitator superfamily transporter YP_001122145.1 1172814 R 418136 CDS YP_001122146.1 134302177 4959784 complement(1174182..1174979) 1 NC_009257.1 glutamate racemase 1174979 murI 4959784 murI Francisella tularensis subsp. tularensis WY96-3418 glutamate racemase YP_001122146.1 1174182 R 418136 CDS YP_001122147.1 134302178 4959793 complement(1174979..1175809) 1 NC_009257.1 hypothetical protein 1175809 4959793 FTW_1245 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122147.1 1174979 R 418136 CDS YP_001122148.1 134302179 4959658 complement(1175813..1177819) 1 NC_009257.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1177819 uvrB 4959658 uvrB Francisella tularensis subsp. tularensis WY96-3418 excinuclease ABC subunit B YP_001122148.1 1175813 R 418136 CDS YP_001122149.1 134302180 4959804 complement(1177821..1179269) 1 NC_009257.1 exonuclease 1179269 4959804 FTW_1247 Francisella tularensis subsp. tularensis WY96-3418 exonuclease YP_001122149.1 1177821 R 418136 CDS YP_001122150.1 134302181 4959816 complement(1179403..1180125) 1 NC_009257.1 short chain dehydrogenase/reductase family oxidoreductase 1180125 4959816 FTW_1248 Francisella tularensis subsp. tularensis WY96-3418 short chain dehydrogenase/reductase family oxidoreductase YP_001122150.1 1179403 R 418136 CDS YP_001122151.1 134302182 4959830 1180241..1181140 1 NC_009257.1 LysR family transcriptional regulator 1181140 4959830 FTW_1249 Francisella tularensis subsp. tularensis WY96-3418 LysR family transcriptional regulator YP_001122151.1 1180241 D 418136 CDS YP_001122152.1 134302183 4959799 complement(1181151..1182056) 1 NC_009257.1 hypothetical protein 1182056 4959799 FTW_1250 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122152.1 1181151 R 418136 CDS YP_001122153.1 134302184 4959854 complement(1182043..1183125) 1 NC_009257.1 hypothetical protein 1183125 4959854 FTW_1251 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122153.1 1182043 R 418136 CDS YP_001122154.1 134302185 4959876 1183268..1185151 1 NC_009257.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 1185151 gidA 4959876 gidA Francisella tularensis subsp. tularensis WY96-3418 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_001122154.1 1183268 D 418136 CDS YP_001122155.1 134302186 4959835 1185163..1185555 1 NC_009257.1 hypothetical protein 1185555 4959835 FTW_1253 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122155.1 1185163 D 418136 CDS YP_001122156.1 134302187 4959899 1185569..1186939 1 NC_009257.1 hypothetical protein 1186939 4959899 FTW_1254 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122156.1 1185569 D 418136 CDS YP_001122157.1 134302188 4959905 1186941..1187615 1 NC_009257.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 1187615 rpiA 4959905 rpiA Francisella tularensis subsp. tularensis WY96-3418 ribose-5-phosphate isomerase A YP_001122157.1 1186941 D 418136 CDS YP_001122158.1 134302189 4959925 complement(join(1189588..1190139,1190139..1190468)) 1 NC_009257.1 Transposase, member of the IS630 Tc-1 mariner family. This gene contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' which permits frameshifting to produce a single ORF; programmed frameshift; transposase ISFtu1 1190468 4959925 FTW_1258 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122158.1 1189588 R 418136 CDS YP_001122159.1 134302190 4959941 complement(1190603..1192051) 1 NC_009257.1 hypothetical protein 1192051 4959941 FTW_1260 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122159.1 1190603 R 418136 CDS YP_001122160.1 134302191 4960014 complement(1192068..1193741) 1 NC_009257.1 lipoprotein 1193741 4960014 FTW_1261 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001122160.1 1192068 R 418136 CDS YP_001122161.1 134302192 4960010 complement(1193904..1195718) 1 NC_009257.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1195718 4960010 FTW_1262 Francisella tularensis subsp. tularensis WY96-3418 malate dehydrogenase YP_001122161.1 1193904 R 418136 CDS YP_001122162.1 134302193 4960020 1195869..1196789 1 NC_009257.1 riboflavin biosynthesis protein RibF 1196789 ribF 4960020 ribF Francisella tularensis subsp. tularensis WY96-3418 riboflavin biosynthesis protein RibF YP_001122162.1 1195869 D 418136 CDS YP_001122163.1 134302194 4960029 1196882..1199689 1 NC_009257.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1199689 ileS 4960029 ileS Francisella tularensis subsp. tularensis WY96-3418 isoleucyl-tRNA synthetase YP_001122163.1 1196882 D 418136 CDS YP_001122164.1 134302195 4960030 1199682..1200161 1 NC_009257.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1200161 lspA 4960030 lspA Francisella tularensis subsp. tularensis WY96-3418 lipoprotein signal peptidase YP_001122164.1 1199682 D 418136 CDS YP_001122165.1 134302196 4960036 complement(1200156..1200623) 1 NC_009257.1 hypothetical protein 1200623 4960036 FTW_1266 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122165.1 1200156 R 418136 CDS YP_001122166.1 134302197 4959897 1200781..1201401 1 NC_009257.1 ribosomal large subunit methyltransferase J 1201401 rrmJ 4959897 rrmJ Francisella tularensis subsp. tularensis WY96-3418 ribosomal large subunit methyltransferase J YP_001122166.1 1200781 D 418136 CDS YP_001122167.1 134302198 4960043 complement(1201461..1202051) 1 NC_009257.1 metal-dependent phosphohydrolase 1202051 4960043 FTW_1268 Francisella tularensis subsp. tularensis WY96-3418 metal-dependent phosphohydrolase YP_001122167.1 1201461 R 418136 CDS YP_001122168.1 134302199 4960025 complement(1202048..1202929) 1 NC_009257.1 hypothetical protein 1202929 4960025 FTW_1269 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122168.1 1202048 R 418136 CDS YP_001122169.1 134302200 4960060 complement(1202932..1203639) 1 NC_009257.1 glutamine amidotransferase 1203639 4960060 FTW_1270 Francisella tularensis subsp. tularensis WY96-3418 glutamine amidotransferase YP_001122169.1 1202932 R 418136 CDS YP_001122170.1 134302201 4960061 complement(1203653..1204567) 1 NC_009257.1 ParB-like nuclease 1204567 4960061 FTW_1271 Francisella tularensis subsp. tularensis WY96-3418 ParB-like nuclease YP_001122170.1 1203653 R 418136 CDS YP_001122171.1 134302202 4960066 complement(1204560..1205201) 1 NC_009257.1 CobQ/CobB/MinD/ParA nucleotide binding domain-containing protein 1205201 4960066 FTW_1272 Francisella tularensis subsp. tularensis WY96-3418 CobQ/CobB/MinD/ParA nucleotide binding domain-containing protein YP_001122171.1 1204560 R 418136 CDS YP_001122172.1 134302203 4960078 1205400..1207694 1 NC_009257.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity; DNA topoisomerase I 1207694 topA 4960078 topA Francisella tularensis subsp. tularensis WY96-3418 DNA topoisomerase I YP_001122172.1 1205400 D 418136 CDS YP_001122173.1 134302204 4960077 complement(1207748..1209190) 1 NC_009257.1 putative O antigen polymerase 1209190 4960077 FTW_1274 Francisella tularensis subsp. tularensis WY96-3418 putative O antigen polymerase YP_001122173.1 1207748 R 418136 CDS YP_001122174.1 134302205 4960082 complement(1209263..1209730) 1 NC_009257.1 lipoprotein 1209730 4960082 FTW_1275 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001122174.1 1209263 R 418136 CDS YP_001122175.1 134302206 4960087 complement(1209763..1210212) 1 NC_009257.1 hypothetical protein 1210212 4960087 FTW_1276 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122175.1 1209763 R 418136 CDS YP_001122176.1 134302207 4960083 complement(1210366..1210809) 1 NC_009257.1 hypothetical protein 1210809 4960083 FTW_1277 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122176.1 1210366 R 418136 CDS YP_001122177.1 134302208 4960096 complement(1211003..1211452) 1 NC_009257.1 lipoprotein 1211452 4960096 FTW_1278 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001122177.1 1211003 R 418136 CDS YP_001122178.1 134302209 4960118 complement(1211533..1211904) 1 NC_009257.1 hypothetical protein 1211904 4960118 FTW_1279 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122178.1 1211533 R 418136 CDS YP_001122179.1 134302210 4960109 1211996..1214017 1 NC_009257.1 M3 family peptidase 1214017 4960109 FTW_1280 Francisella tularensis subsp. tularensis WY96-3418 M3 family peptidase YP_001122179.1 1211996 D 418136 CDS YP_001122180.1 134302211 4960123 1214084..1214437 1 NC_009257.1 hypothetical protein 1214437 4960123 FTW_1281 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122180.1 1214084 D 418136 CDS YP_001122181.1 134302212 4960125 complement(1214434..1215531) 1 NC_009257.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1215531 purK 4960125 purK Francisella tularensis subsp. tularensis WY96-3418 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_001122181.1 1214434 R 418136 CDS YP_001122182.1 134302213 4960134 complement(1215535..1216026) 1 NC_009257.1 phosphoribosylaminoimidazole carboxylase catalytic subunit 1216026 purE 4960134 purE Francisella tularensis subsp. tularensis WY96-3418 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_001122182.1 1215535 R 418136 CDS YP_001122183.1 134302214 4960136 complement(1216143..1216718) 1 NC_009257.1 phosphoribosylglycinamide formyltransferase 1216718 purN 4960136 purN Francisella tularensis subsp. tularensis WY96-3418 phosphoribosylglycinamide formyltransferase YP_001122183.1 1216143 R 418136 CDS YP_001122184.1 134302215 4960137 complement(1216722..1219034) 1 NC_009257.1 fusion protein PurC/PurD 1219034 purCD 4960137 purCD Francisella tularensis subsp. tularensis WY96-3418 fusion protein PurC/PurD YP_001122184.1 1216722 R 418136 CDS YP_001122185.1 134302216 4960159 complement(1219034..1220077) 1 NC_009257.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1220077 purM 4960159 purM Francisella tularensis subsp. tularensis WY96-3418 phosphoribosylaminoimidazole synthetase YP_001122185.1 1219034 R 418136 CDS YP_001122186.1 134302217 4960146 complement(1220311..1221159) 1 NC_009257.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1221159 folD 4960146 folD Francisella tularensis subsp. tularensis WY96-3418 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001122186.1 1220311 R 418136 CDS YP_001122187.1 134302218 4958971 complement(1221299..1222018) 1 NC_009257.1 lipid A 1-phosphatase 1222018 4958971 FTW_1288 Francisella tularensis subsp. tularensis WY96-3418 lipid A 1-phosphatase YP_001122187.1 1221299 R 418136 CDS YP_001122188.1 134302219 4958712 1222402..1222809 1 NC_009257.1 type IV pilus assembly protein 1222809 pilA 4958712 pilA Francisella tularensis subsp. tularensis WY96-3418 type IV pilus assembly protein YP_001122188.1 1222402 D 418136 CDS YP_001122189.1 134302220 4959009 1222940..1223380 1 NC_009257.1 type IV pili fiber building block protein 1223380 4959009 FTW_1290 Francisella tularensis subsp. tularensis WY96-3418 type IV pili fiber building block protein YP_001122189.1 1222940 D 418136 CDS YP_001122190.1 134302221 4960167 complement(1225584..1227233) 1 NC_009257.1 DNA repair protein RecN 1227233 recN 4960167 recN Francisella tularensis subsp. tularensis WY96-3418 DNA repair protein RecN YP_001122190.1 1225584 R 418136 CDS YP_001122191.1 134302222 4959236 complement(1227319..1228206) 1 NC_009257.1 cation diffusion facilitator family transporter 1228206 4959236 FTW_1294 Francisella tularensis subsp. tularensis WY96-3418 cation diffusion facilitator family transporter YP_001122191.1 1227319 R 418136 CDS YP_001122192.1 134302223 4958892 1228409..1229599 1 NC_009257.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1229599 4958892 FTW_1295 Francisella tularensis subsp. tularensis WY96-3418 aspartate aminotransferase YP_001122192.1 1228409 D 418136 CDS YP_001122193.1 134302224 4960162 complement(1230851..1231213) 1 NC_009257.1 mannose-6-phosphate isomerase 1231213 4960162 FTW_1298 Francisella tularensis subsp. tularensis WY96-3418 mannose-6-phosphate isomerase YP_001122193.1 1230851 R 418136 CDS YP_001122194.1 134302225 4959153 1231363..1232757 1 NC_009257.1 amino acid permease 1232757 4959153 FTW_1299 Francisella tularensis subsp. tularensis WY96-3418 amino acid permease YP_001122194.1 1231363 D 418136 CDS YP_001122195.1 134302226 4959387 complement(1232732..1233523) 1 NC_009257.1 sterol desaturase 1233523 4959387 FTW_1300 Francisella tularensis subsp. tularensis WY96-3418 sterol desaturase YP_001122195.1 1232732 R 418136 CDS YP_001122196.1 134302227 4958998 complement(1233527..1234084) 1 NC_009257.1 copper/zinc superoxide dismutase 1234084 sodC 4958998 sodC Francisella tularensis subsp. tularensis WY96-3418 copper/zinc superoxide dismutase YP_001122196.1 1233527 R 418136 CDS YP_001122197.1 134302228 4958954 1234364..1234756 1 NC_009257.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1234756 msrB 4958954 msrB Francisella tularensis subsp. tularensis WY96-3418 methionine sulfoxide reductase B YP_001122197.1 1234364 D 418136 CDS YP_001122198.1 134302229 4958860 1234775..1235428 1 NC_009257.1 hypothetical protein 1235428 4958860 FTW_1303 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122198.1 1234775 D 418136 CDS YP_001122199.1 134302230 4958836 1235569..1236627 1 NC_009257.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1236627 aroC 4958836 aroC Francisella tularensis subsp. tularensis WY96-3418 chorismate synthase YP_001122199.1 1235569 D 418136 CDS YP_001122200.1 134302231 4959327 1236630..1237229 1 NC_009257.1 hypothetical protein 1237229 4959327 FTW_1305 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122200.1 1236630 D 418136 CDS YP_001122201.1 134302232 4959067 1237226..1237996 1 NC_009257.1 hypothetical protein 1237996 4959067 FTW_1306 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122201.1 1237226 D 418136 CDS YP_001122202.1 134302233 4958776 1238004..1239374 1 NC_009257.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 1239374 radA 4958776 radA Francisella tularensis subsp. tularensis WY96-3418 DNA repair protein RadA YP_001122202.1 1238004 D 418136 CDS YP_001122203.1 134302234 4959114 1239379..1239915 1 NC_009257.1 colicin V production (cvpA ) family protein 1239915 4959114 FTW_1308 Francisella tularensis subsp. tularensis WY96-3418 colicin V production (cvpA ) family protein YP_001122203.1 1239379 D 418136 CDS YP_001122204.1 134302235 4959454 complement(1239916..1240914) 1 NC_009257.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1240914 gpsA 4959454 gpsA Francisella tularensis subsp. tularensis WY96-3418 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_001122204.1 1239916 R 418136 CDS YP_001122205.1 134302236 4958965 complement(1240952..1241089) 1 NC_009257.1 hypothetical protein 1241089 4958965 FTW_1310 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122205.1 1240952 R 418136 CDS YP_001122206.1 134302237 4959101 1241091..1241222 1 NC_009257.1 hypothetical protein 1241222 4959101 FTW_1311 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122206.1 1241091 D 418136 CDS YP_001122207.1 134302238 4959077 1242030..1242395 1 NC_009257.1 ArsR family transcriptional regulator 1242395 4959077 FTW_1314 Francisella tularensis subsp. tularensis WY96-3418 ArsR family transcriptional regulator YP_001122207.1 1242030 D 418136 CDS YP_001122208.1 134302239 4960176 complement(1245422..1246477) 1 NC_009257.1 hypothetical protein 1246477 4960176 FTW_1319 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122208.1 1245422 R 418136 CDS YP_001122209.1 134302240 4960178 1246616..1247512 1 NC_009257.1 LysR family transcriptional regulator 1247512 4960178 FTW_1320 Francisella tularensis subsp. tularensis WY96-3418 LysR family transcriptional regulator YP_001122209.1 1246616 D 418136 CDS YP_001122210.1 134302241 4960182 1247560..1248135 1 NC_009257.1 LemA-like protein 1248135 4960182 FTW_1321 Francisella tularensis subsp. tularensis WY96-3418 LemA-like protein YP_001122210.1 1247560 D 418136 CDS YP_001122211.1 134302242 4960186 1248139..1249212 1 NC_009257.1 putative metalloprotease; heat shock protein HtpX 1249212 4960186 FTW_1322 Francisella tularensis subsp. tularensis WY96-3418 heat shock protein HtpX YP_001122211.1 1248139 D 418136 CDS YP_001122212.1 134302243 4960213 1250329..1250652 1 NC_009257.1 hypothetical protein 1250652 4960213 FTW_1325 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122212.1 1250329 D 418136 CDS YP_001122213.1 134302244 4960230 complement(1250706..1251413) 1 NC_009257.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 1251413 rph 4960230 rph Francisella tularensis subsp. tularensis WY96-3418 ribonuclease PH YP_001122213.1 1250706 R 418136 CDS YP_001122214.1 134302245 4959174 1251512..1252018 1 NC_009257.1 chorismate lyase 1252018 4959174 FTW_1327 Francisella tularensis subsp. tularensis WY96-3418 chorismate lyase YP_001122214.1 1251512 D 418136 CDS YP_001122215.1 134302246 4960233 1252021..1252890 1 NC_009257.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 1252890 ubiA 4960233 ubiA Francisella tularensis subsp. tularensis WY96-3418 4-hydroxybenzoate polyprenyltransferase YP_001122215.1 1252021 D 418136 CDS YP_001122216.1 134302247 4960252 1252887..1253246 1 NC_009257.1 hypothetical protein 1253246 4960252 FTW_1329 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122216.1 1252887 D 418136 CDS YP_001122217.1 134302248 4960262 1253266..1253688 1 NC_009257.1 hypothetical protein 1253688 4960262 FTW_1330 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122217.1 1253266 D 418136 CDS YP_001122218.1 134302249 4960264 complement(1253667..1254905) 1 NC_009257.1 arsenical pump membrane protein 1254905 4960264 FTW_1331 Francisella tularensis subsp. tularensis WY96-3418 arsenical pump membrane protein YP_001122218.1 1253667 R 418136 CDS YP_001122219.1 134302250 4959617 complement(1256553..1257311) 1 NC_009257.1 hypothetical protein 1257311 4959617 FTW_1334 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122219.1 1256553 R 418136 CDS YP_001122220.1 134302251 4960314 complement(1257335..1257958) 1 NC_009257.1 hypothetical protein 1257958 4960314 FTW_1335 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122220.1 1257335 R 418136 CDS YP_001122221.1 134302252 4960325 complement(1258007..1258819) 1 NC_009257.1 bile acid symporter family protein 1258819 4960325 FTW_1336 Francisella tularensis subsp. tularensis WY96-3418 bile acid symporter family protein YP_001122221.1 1258007 R 418136 CDS YP_001122222.1 134302253 4960329 complement(1260609..1262108) 1 NC_009257.1 deoxyribodipyrimidine photolyase 1262108 phrB2 4960329 phrB2 Francisella tularensis subsp. tularensis WY96-3418 deoxyribodipyrimidine photolyase YP_001122222.1 1260609 R 418136 CDS YP_001122223.1 134302254 4960341 complement(1262089..1262319) 1 NC_009257.1 hypothetical protein 1262319 4960341 FTW_1340 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122223.1 1262089 R 418136 CDS YP_001122224.1 134302255 4959664 complement(1262343..1263065) 1 NC_009257.1 hypothetical protein 1263065 4959664 FTW_1341 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122224.1 1262343 R 418136 CDS YP_001122225.1 134302256 4960352 complement(1264594..1265217) 1 NC_009257.1 OmpA family protein 1265217 4960352 FTW_1344 Francisella tularensis subsp. tularensis WY96-3418 OmpA family protein YP_001122225.1 1264594 R 418136 CDS YP_001122226.1 134302257 4960362 complement(1265236..1265481) 1 NC_009257.1 lipoprotein 1265481 4960362 FTW_1345 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001122226.1 1265236 R 418136 CDS YP_001122227.1 134302258 4960373 complement(1265491..1266798) 1 NC_009257.1 beta propeller repeat-containing outer membrane protein 1266798 tolB 4960373 tolB Francisella tularensis subsp. tularensis WY96-3418 beta propeller repeat-containing outer membrane protein YP_001122227.1 1265491 R 418136 CDS YP_001122228.1 134302259 4960378 complement(1266810..1267721) 1 NC_009257.1 protein TolA 1267721 tolA 4960378 tolA Francisella tularensis subsp. tularensis WY96-3418 protein TolA YP_001122228.1 1266810 R 418136 CDS YP_001122229.1 134302260 4960366 complement(1267708..1268154) 1 NC_009257.1 TolR protein 1268154 tolR 4960366 tolR Francisella tularensis subsp. tularensis WY96-3418 TolR protein YP_001122229.1 1267708 R 418136 CDS YP_001122230.1 134302261 4960400 complement(1268164..1268883) 1 NC_009257.1 TolQ protein 1268883 tolQ 4960400 tolQ Francisella tularensis subsp. tularensis WY96-3418 TolQ protein YP_001122230.1 1268164 R 418136 CDS YP_001122231.1 134302262 4960394 1269024..1269248 1 NC_009257.1 hypothetical protein 1269248 4960394 FTW_1350 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122231.1 1269024 D 418136 CDS YP_001122232.1 134302263 4960416 complement(1269253..1270074) 1 NC_009257.1 CDP-alcohol phosphatidyltransferase 1270074 4960416 FTW_1351 Francisella tularensis subsp. tularensis WY96-3418 CDP-alcohol phosphatidyltransferase YP_001122232.1 1269253 R 418136 CDS YP_001122233.1 134302264 4960417 complement(1270083..1270445) 1 NC_009257.1 chorismate mutase 1270445 aroH 4960417 aroH Francisella tularensis subsp. tularensis WY96-3418 chorismate mutase YP_001122233.1 1270083 R 418136 CDS YP_001122234.1 134302265 4960428 complement(1270447..1271403) 1 NC_009257.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1271403 ispH 4960428 ispH Francisella tularensis subsp. tularensis WY96-3418 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_001122234.1 1270447 R 418136 CDS YP_001122235.1 134302266 4960426 complement(1271384..1271848) 1 NC_009257.1 FKBP-type peptidyl-prolyl cis-trans isomerase 1271848 4960426 FTW_1354 Francisella tularensis subsp. tularensis WY96-3418 FKBP-type peptidyl-prolyl cis-trans isomerase YP_001122235.1 1271384 R 418136 CDS YP_001122236.1 134302267 4960430 1272040..1273293 1 NC_009257.1 ompA family protein 1273293 4960430 FTW_1355 Francisella tularensis subsp. tularensis WY96-3418 ompA family protein YP_001122236.1 1272040 D 418136 CDS YP_001122237.1 134302268 4960432 1273293..1274399 1 NC_009257.1 DNA processing protein DprA 1274399 dprA 4960432 dprA Francisella tularensis subsp. tularensis WY96-3418 DNA processing protein DprA YP_001122237.1 1273293 D 418136 CDS YP_001122238.1 134302269 4960434 1274474..1276189 1 NC_009257.1 premease membrane region 1276189 4960434 FTW_1357 Francisella tularensis subsp. tularensis WY96-3418 premease membrane region YP_001122238.1 1274474 D 418136 CDS YP_001122239.1 134302270 4959105 1276202..1277788 1 NC_009257.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1277788 4959105 FTW_1358 Francisella tularensis subsp. tularensis WY96-3418 aspartate aminotransferase YP_001122239.1 1276202 D 418136 CDS YP_001122240.1 134302271 4959329 1277855..1279168 1 NC_009257.1 xanthine/uracil permease family/inorganic anion transporter, sulfate permease (SulP) family protein 1279168 4959329 FTW_1359 Francisella tularensis subsp. tularensis WY96-3418 xanthine/uracil permease family/inorganic anion transporter, sulfate permease (SulP) family protein YP_001122240.1 1277855 D 418136 CDS YP_001122241.1 134302272 4960133 1279245..1279490 1 NC_009257.1 hypothetical protein 1279490 4960133 FTW_1360 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122241.1 1279245 D 418136 CDS YP_001122242.1 134302273 4960353 1279667..1280002 1 NC_009257.1 hypothetical protein 1280002 4960353 FTW_1361 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122242.1 1279667 D 418136 CDS YP_001122243.1 134302274 4960131 complement(1280026..1280379) 1 NC_009257.1 arsenate reductase 1280379 4960131 FTW_1362 Francisella tularensis subsp. tularensis WY96-3418 arsenate reductase YP_001122243.1 1280026 R 418136 CDS YP_001122244.1 134302275 4960059 complement(1280397..1281002) 1 NC_009257.1 NUDIX family hydrolase 1281002 4960059 FTW_1363 Francisella tularensis subsp. tularensis WY96-3418 NUDIX family hydrolase YP_001122244.1 1280397 R 418136 CDS YP_001122245.1 134302276 4959961 complement(join(1281172..1281723,1281723..1282052)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1282052 4959961 FTW_1364 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122245.1 1281172 R 418136 CDS YP_001122246.1 134302277 4959850 complement(1282205..1282579) 1 NC_009257.1 hypothetical protein 1282579 4959850 FTW_1366 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122246.1 1282205 R 418136 CDS YP_001122247.1 134302278 4959534 complement(1285972..1286478) 1 NC_009257.1 hypothetical protein 1286478 4959534 FTW_1369 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122247.1 1285972 R 418136 CDS YP_001122248.1 134302279 4959533 complement(1286567..1287472) 1 NC_009257.1 hypothetical protein 1287472 4959533 FTW_1370 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122248.1 1286567 R 418136 CDS YP_001122249.1 134302280 4960469 complement(1290685..1291191) 1 NC_009257.1 putative antirestriction protein 1291191 4960469 FTW_1373 Francisella tularensis subsp. tularensis WY96-3418 putative antirestriction protein YP_001122249.1 1290685 R 418136 CDS YP_001122250.1 134302281 4959291 1291424..1291558 1 NC_009257.1 hypothetical protein 1291558 4959291 FTW_1374 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122250.1 1291424 D 418136 CDS YP_001122251.1 134302282 4958705 1291835..1292464 1 NC_009257.1 hypothetical protein 1292464 4958705 FTW_1375 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122251.1 1291835 D 418136 CDS YP_001122252.1 134302283 4958677 complement(1292622..1293134) 1 NC_009257.1 hypothetical protein 1293134 4958677 FTW_1376 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122252.1 1292622 R 418136 CDS YP_001122253.1 134302284 4958754 join(1293228..1293557,1293557..1294108) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1294108 4958754 FTW_1377 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122253.1 1293228 D 418136 CDS YP_001122254.1 134302285 4958976 complement(1294195..1294314) 1 NC_009257.1 hypothetical protein 1294314 4958976 FTW_1379 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122254.1 1294195 R 418136 CDS YP_001122255.1 134302286 4959242 complement(1294422..1294631) 1 NC_009257.1 hypothetical protein 1294631 4959242 FTW_1380 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122255.1 1294422 R 418136 CDS YP_001122256.1 134302287 4958916 1294896..1295111 1 NC_009257.1 transcriptional regulator 1295111 4958916 FTW_1381 Francisella tularensis subsp. tularensis WY96-3418 transcriptional regulator YP_001122256.1 1294896 D 418136 CDS YP_001122257.1 134302288 4959305 complement(1297960..1298838) 1 NC_009257.1 hypothetical protein 1298838 4959305 FTW_1386 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122257.1 1297960 R 418136 CDS YP_001122258.1 134302289 4958950 complement(1298838..1299641) 1 NC_009257.1 hypothetical protein 1299641 4958950 FTW_1387 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122258.1 1298838 R 418136 CDS YP_001122259.1 134302290 4959341 1299867..1300289 1 NC_009257.1 hypothetical protein 1300289 4959341 FTW_1388 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122259.1 1299867 D 418136 CDS YP_001122260.1 134302291 4959219 complement(1300305..1300562) 1 NC_009257.1 hypothetical protein 1300562 4959219 FTW_1389 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122260.1 1300305 R 418136 CDS YP_001122261.1 134302292 4959355 complement(1300567..1301427) 1 NC_009257.1 Required for efficient pilin antigenic variation; recombination associated protein 1301427 rdgC 4959355 rdgC Francisella tularensis subsp. tularensis WY96-3418 recombination associated protein YP_001122261.1 1300567 R 418136 CDS YP_001122262.1 134302293 4958909 1301609..1302607 1 NC_009257.1 rhodanese-like domain-containing protein 1302607 4958909 FTW_1391 Francisella tularensis subsp. tularensis WY96-3418 rhodanese-like domain-containing protein YP_001122262.1 1301609 D 418136 CDS YP_001122263.1 134302294 4959406 complement(1302738..1303568) 1 NC_009257.1 hypothetical protein 1303568 4959406 FTW_1392 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122263.1 1302738 R 418136 CDS YP_001122264.1 134302295 4959335 complement(1303624..1305639) 1 NC_009257.1 ATP-dependent DNA helicase 1305639 4959335 FTW_1393 Francisella tularensis subsp. tularensis WY96-3418 ATP-dependent DNA helicase YP_001122264.1 1303624 R 418136 CDS YP_001122265.1 134302296 4959332 complement(1305633..1306379) 1 NC_009257.1 putative aminomethyl transferase 1306379 4959332 FTW_1394 Francisella tularensis subsp. tularensis WY96-3418 putative aminomethyl transferase YP_001122265.1 1305633 R 418136 CDS YP_001122266.1 134302297 4959265 1307020..1307508 1 NC_009257.1 isochorismatase hydrolase family protein 1307508 4959265 FTW_1395 Francisella tularensis subsp. tularensis WY96-3418 isochorismatase hydrolase family protein YP_001122266.1 1307020 D 418136 CDS YP_001122267.1 134302298 4959486 1307559..1308182 1 NC_009257.1 nicotinamide mononucleotide transporter 1308182 pnuC2 4959486 pnuC2 Francisella tularensis subsp. tularensis WY96-3418 nicotinamide mononucleotide transporter YP_001122267.1 1307559 D 418136 CDS YP_001122268.1 134302299 4959326 1308195..1308683 1 NC_009257.1 isochorismatase hydrolase family protein 1308683 4959326 FTW_1397 Francisella tularensis subsp. tularensis WY96-3418 isochorismatase hydrolase family protein YP_001122268.1 1308195 D 418136 CDS YP_001122269.1 134302300 4959325 complement(1308840..1309295) 1 NC_009257.1 hypothetical protein 1309295 4959325 FTW_1398 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122269.1 1308840 R 418136 CDS YP_001122270.1 134302301 4959322 complement(1309321..1310340) 1 NC_009257.1 transaldolase B 1310340 tal 4959322 tal Francisella tularensis subsp. tularensis WY96-3418 transaldolase B YP_001122270.1 1309321 R 418136 CDS YP_001122271.1 134302302 4959317 complement(1310420..1311799) 1 NC_009257.1 cytosol aminopeptidase 1311799 4959317 FTW_1400 Francisella tularensis subsp. tularensis WY96-3418 cytosol aminopeptidase YP_001122271.1 1310420 R 418136 CDS YP_001122272.1 134302303 4959314 complement(1311802..1313184) 1 NC_009257.1 outer membrane efflux protein 1313184 4959314 FTW_1401 Francisella tularensis subsp. tularensis WY96-3418 outer membrane efflux protein YP_001122272.1 1311802 R 418136 CDS YP_001122273.1 134302304 4959311 complement(1313192..1315789) 1 NC_009257.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1315789 alaS 4959311 alaS Francisella tularensis subsp. tularensis WY96-3418 alanyl-tRNA synthetase YP_001122273.1 1313192 R 418136 CDS YP_001122274.1 134302305 4959244 1315945..1316391 1 NC_009257.1 hypothetical protein 1316391 4959244 FTW_1403 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122274.1 1315945 D 418136 CDS YP_001122275.1 134302306 4959309 complement(1316388..1318454) 1 NC_009257.1 UvrD/REP helicase 1318454 4959309 FTW_1404 Francisella tularensis subsp. tularensis WY96-3418 UvrD/REP helicase YP_001122275.1 1316388 R 418136 CDS YP_001122276.1 134302307 4959308 complement(1318481..1318816) 1 NC_009257.1 hypothetical protein 1318816 4959308 FTW_1405 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122276.1 1318481 R 418136 CDS YP_001122277.1 134302308 4959302 1318847..1319254 1 NC_009257.1 iojap family protein 1319254 4959302 FTW_1407 Francisella tularensis subsp. tularensis WY96-3418 iojap family protein YP_001122277.1 1318847 D 418136 CDS YP_001122278.1 134302309 4959127 1320430..1320720 1 NC_009257.1 hypothetical protein 1320720 4959127 FTW_1410 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122278.1 1320430 D 418136 CDS YP_001122279.1 134302310 4960435 1320741..1321862 1 NC_009257.1 DSBA-like thioredoxin domain-containing protein 1321862 4960435 FTW_1411 Francisella tularensis subsp. tularensis WY96-3418 DSBA-like thioredoxin domain-containing protein YP_001122279.1 1320741 D 418136 CDS YP_001122280.1 134302311 4960444 complement(1323338..1324192) 1 NC_009257.1 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae; bifunctional methionine sulfoxide reductase B/A protein 1324192 4960444 FTW_1414 Francisella tularensis subsp. tularensis WY96-3418 bifunctional methionine sulfoxide reductase B/A protein YP_001122280.1 1323338 R 418136 CDS YP_001122281.1 134302312 4960239 1324321..1324797 1 NC_009257.1 tryptophan-rich sensory (TspO)/MBR family protein 1324797 4960239 FTW_1415 Francisella tularensis subsp. tularensis WY96-3418 tryptophan-rich sensory (TspO)/MBR family protein YP_001122281.1 1324321 D 418136 CDS YP_001122282.1 134302313 4960462 1326885..1327637 1 NC_009257.1 rRNA methyltransferase 1327637 spoU 4960462 spoU Francisella tularensis subsp. tularensis WY96-3418 rRNA methyltransferase YP_001122282.1 1326885 D 418136 CDS YP_001122283.1 134302314 4958761 1327731..1328699 1 NC_009257.1 linear amide C-N hydrolase, choloylglycine hydrolase family protein 1328699 4958761 FTW_1419 Francisella tularensis subsp. tularensis WY96-3418 linear amide C-N hydrolase, choloylglycine hydrolase family protein YP_001122283.1 1327731 D 418136 CDS YP_001122284.1 134302315 4958878 1328864..1329217 1 NC_009257.1 hypothetical protein 1329217 4958878 FTW_1420 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122284.1 1328864 D 418136 CDS YP_001122285.1 134302316 4958718 complement(1330480..1331052) 1 NC_009257.1 CRISPR-associated Cas4 family protein 1331052 4958718 FTW_1423 Francisella tularensis subsp. tularensis WY96-3418 CRISPR-associated Cas4 family protein YP_001122285.1 1330480 R 418136 CDS YP_001122286.1 134302317 4958779 complement(1331039..1331332) 1 NC_009257.1 putative CRISPR-associated Cas2 family protein 1331332 4958779 FTW_1424 Francisella tularensis subsp. tularensis WY96-3418 putative CRISPR-associated Cas2 family protein YP_001122286.1 1331039 R 418136 CDS YP_001122287.1 134302318 4958852 complement(1332426..1335803) 1 NC_009257.1 CRISPR-associated large protein 1335803 4958852 FTW_1427 Francisella tularensis subsp. tularensis WY96-3418 CRISPR-associated large protein YP_001122287.1 1332426 R 418136 CDS YP_001122288.1 134302319 4958945 complement(1336465..1337646) 1 NC_009257.1 ompA family protein 1337646 4958945 FTW_1428 Francisella tularensis subsp. tularensis WY96-3418 ompA family protein YP_001122288.1 1336465 R 418136 CDS YP_001122289.1 134302320 4958922 complement(1337753..1337998) 1 NC_009257.1 4Fe-4S ferredoxin 1337998 4958922 FTW_1429 Francisella tularensis subsp. tularensis WY96-3418 4Fe-4S ferredoxin YP_001122289.1 1337753 R 418136 CDS YP_001122290.1 134302321 4959087 complement(1338003..1338491) 1 NC_009257.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1338491 coaD 4959087 coaD Francisella tularensis subsp. tularensis WY96-3418 phosphopantetheine adenylyltransferase YP_001122290.1 1338003 R 418136 CDS YP_001122291.1 134302322 4958985 complement(1338503..1339054) 1 NC_009257.1 hypothetical protein 1339054 4958985 FTW_1431 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122291.1 1338503 R 418136 CDS YP_001122292.1 134302323 4959030 complement(1339068..1339424) 1 NC_009257.1 iron-sulfur cluster assembly accessory protein/HesB family protein 1339424 4959030 FTW_1432 Francisella tularensis subsp. tularensis WY96-3418 iron-sulfur cluster assembly accessory protein/HesB family protein YP_001122292.1 1339068 R 418136 CDS YP_001122293.1 134302324 4958686 complement(1339445..1340668) 1 NC_009257.1 sufS subfamily cysteine desulfurase 1340668 4958686 FTW_1433 Francisella tularensis subsp. tularensis WY96-3418 sufS subfamily cysteine desulfurase YP_001122293.1 1339445 R 418136 CDS YP_001122294.1 134302325 4959303 complement(1340771..1342144) 1 NC_009257.1 L-serine ammonia-lyase 1342144 sdaA 4959303 sdaA Francisella tularensis subsp. tularensis WY96-3418 L-serine ammonia-lyase YP_001122294.1 1340771 R 418136 CDS YP_001122295.1 134302326 4959324 complement(1342200..1342868) 1 NC_009257.1 hypothetical protein 1342868 4959324 FTW_1435 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122295.1 1342200 R 418136 CDS YP_001122296.1 134302327 4959132 complement(1342894..1343736) 1 NC_009257.1 prephenate dehydratase 1343736 pheA 4959132 pheA Francisella tularensis subsp. tularensis WY96-3418 prephenate dehydratase YP_001122296.1 1342894 R 418136 CDS YP_001122297.1 134302328 4958737 complement(1345510..1346607) 1 NC_009257.1 alanine racemase 1346607 alr 4958737 alr Francisella tularensis subsp. tularensis WY96-3418 alanine racemase YP_001122297.1 1345510 R 418136 CDS YP_001122298.1 134302329 4958795 complement(1346620..1348113) 1 NC_009257.1 amino acid/peptide transporter (peptide:H+ symporter) 1348113 4958795 FTW_1440 Francisella tularensis subsp. tularensis WY96-3418 amino acid/peptide transporter (peptide:H+ symporter) YP_001122298.1 1346620 R 418136 CDS YP_001122299.1 134302330 4958818 complement(1348238..1348945) 1 NC_009257.1 hypothetical protein 1348945 4958818 FTW_1441 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122299.1 1348238 R 418136 CDS YP_001122300.1 134302331 4959438 complement(1348957..1349355) 1 NC_009257.1 hypothetical protein 1349355 4959438 FTW_1442 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122300.1 1348957 R 418136 CDS YP_001122301.1 134302332 4959412 1349435..1350457 1 NC_009257.1 hypothetical protein 1350457 4959412 FTW_1443 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122301.1 1349435 D 418136 CDS YP_001122302.1 134302333 4958825 complement(1350446..1351096) 1 NC_009257.1 HAD-superfamily hydrolase 1351096 4958825 FTW_1444 Francisella tularensis subsp. tularensis WY96-3418 HAD-superfamily hydrolase YP_001122302.1 1350446 R 418136 CDS YP_001122303.1 134302334 4960451 complement(1353296..1353628) 1 NC_009257.1 hypothetical protein 1353628 4960451 FTW_1447 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122303.1 1353296 R 418136 CDS YP_001122304.1 134302335 4959707 join(1354599..1354928,1354928..1355479) 1 NC_009257.1 Transposase, member of the IS630 Tc-1 mariner family. This gene contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' which permits frameshifting to produce a single ORF; programmed frameshift; transposase ISFtu1 1355479 4959707 FTW_1451 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122304.1 1354599 D 418136 CDS YP_001122305.1 134302336 4959705 complement(1355480..1355620) 1 NC_009257.1 hypothetical protein 1355620 4959705 FTW_1452 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122305.1 1355480 R 418136 CDS YP_001122306.1 134302337 4959735 1355765..1356886 1 NC_009257.1 polyamine transporter, ATP-binding protein 1356886 4959735 FTW_1453 Francisella tularensis subsp. tularensis WY96-3418 polyamine transporter, ATP-binding protein YP_001122306.1 1355765 D 418136 CDS YP_001122307.1 134302338 4959772 1356886..1357767 1 NC_009257.1 ABC transporter permease 1357767 4959772 FTW_1454 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter permease YP_001122307.1 1356886 D 418136 CDS YP_001122308.1 134302339 4959789 1357781..1358587 1 NC_009257.1 ABC transporter permease 1358587 4959789 FTW_1455 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter permease YP_001122308.1 1357781 D 418136 CDS YP_001122309.1 134302340 4959907 1359596..1360591 1 NC_009257.1 hypothetical protein 1360591 4959907 FTW_1457 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122309.1 1359596 D 418136 CDS YP_001122310.1 134302341 4959937 complement(join(1360787..1361338,1361338..1361667)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1361667 4959937 FTW_1458 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122310.1 1360787 R 418136 CDS YP_001122311.1 134302342 4959695 complement(1361729..1362103) 1 NC_009257.1 hypothetical protein 1362103 4959695 FTW_1460 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122311.1 1361729 R 418136 CDS YP_001122312.1 134302343 4959947 complement(1362170..1364008) 1 NC_009257.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1364008 uvrC 4959947 uvrC Francisella tularensis subsp. tularensis WY96-3418 excinuclease ABC subunit C YP_001122312.1 1362170 R 418136 CDS YP_001122313.1 134302344 4959945 1364117..1365211 1 NC_009257.1 putative ribonuclease D 1365211 4959945 FTW_1462 Francisella tularensis subsp. tularensis WY96-3418 putative ribonuclease D YP_001122313.1 1364117 D 418136 CDS YP_001122314.1 134302345 4960101 1365240..1366454 1 NC_009257.1 Bcr/CflA subfamily drug resistance transporter 1366454 4960101 FTW_1463 Francisella tularensis subsp. tularensis WY96-3418 Bcr/CflA subfamily drug resistance transporter YP_001122314.1 1365240 D 418136 CDS YP_001122315.1 134302346 4959944 complement(1366451..1366828) 1 NC_009257.1 hypothetical protein 1366828 4959944 FTW_1464 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122315.1 1366451 R 418136 CDS YP_001122316.1 134302347 4960032 complement(1367215..1367469) 1 NC_009257.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1367469 rpmA 4960032 rpmA Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L27 YP_001122316.1 1367215 R 418136 CDS YP_001122317.1 134302348 4960040 complement(1367500..1367814) 1 NC_009257.1 50S ribosomal protein L21 1367814 rplU 4960040 rplU Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L21 YP_001122317.1 1367500 R 418136 CDS YP_001122318.1 134302349 4960111 complement(1369876..1372596) 1 NC_009257.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1372596 secA 4960111 secA Francisella tularensis subsp. tularensis WY96-3418 preprotein translocase subunit SecA YP_001122318.1 1369876 R 418136 CDS YP_001122319.1 134302350 4960128 complement(1374207..1374929) 1 NC_009257.1 purine nucleoside phosphorylase 1374929 deoD 4960128 deoD Francisella tularensis subsp. tularensis WY96-3418 purine nucleoside phosphorylase YP_001122319.1 1374207 R 418136 CDS YP_001122320.1 134302351 4960321 complement(join(1375002..1375553,1375553..1375882)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1375882 4960321 FTW_1474 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122320.1 1375002 R 418136 CDS YP_001122321.1 134302352 4958787 complement(1376104..1378050) 1 NC_009257.1 ATP-dependent metallopeptidase HflB 1378050 4958787 FTW_1476 Francisella tularensis subsp. tularensis WY96-3418 ATP-dependent metallopeptidase HflB YP_001122321.1 1376104 R 418136 CDS YP_001122322.1 134302353 4960247 1378261..1379649 1 NC_009257.1 major facilitator superfamily transporter 1379649 4960247 FTW_1477 Francisella tularensis subsp. tularensis WY96-3418 major facilitator superfamily transporter YP_001122322.1 1378261 D 418136 CDS YP_001122323.1 134302354 4960506 complement(1379655..1382477) 1 NC_009257.1 excinuclease ABC subunit A 1382477 uvrA 4960506 uvrA Francisella tularensis subsp. tularensis WY96-3418 excinuclease ABC subunit A YP_001122323.1 1379655 R 418136 CDS YP_001122324.1 134302355 4960268 complement(1382516..1382998) 1 NC_009257.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1382998 greA 4960268 greA Francisella tularensis subsp. tularensis WY96-3418 transcription elongation factor GreA YP_001122324.1 1382516 R 418136 CDS YP_001122325.1 134302356 4960280 complement(1383032..1383616) 1 NC_009257.1 type IV pili fiber building block protein 1383616 4960280 FTW_1480 Francisella tularensis subsp. tularensis WY96-3418 type IV pili fiber building block protein YP_001122325.1 1383032 R 418136 CDS YP_001122326.1 134302357 4960274 complement(1383617..1385239) 1 NC_009257.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1385239 pgi 4960274 pgi Francisella tularensis subsp. tularensis WY96-3418 glucose-6-phosphate isomerase YP_001122326.1 1383617 R 418136 CDS YP_001122327.1 134302358 4960344 complement(1385226..1385879) 1 NC_009257.1 thiamine pyrophosphokinase 1385879 4960344 FTW_1482 Francisella tularensis subsp. tularensis WY96-3418 thiamine pyrophosphokinase YP_001122327.1 1385226 R 418136 CDS YP_001122328.1 134302359 4960348 complement(1385945..1387405) 1 NC_009257.1 inosine-5'-monophosphate dehydrogenase 1387405 guaB 4960348 guaB Francisella tularensis subsp. tularensis WY96-3418 inosine-5'-monophosphate dehydrogenase YP_001122328.1 1385945 R 418136 CDS YP_001122329.1 134302360 4960331 complement(1387506..1388945) 1 NC_009257.1 cytosol aminopeptidase 1388945 4960331 FTW_1484 Francisella tularensis subsp. tularensis WY96-3418 cytosol aminopeptidase YP_001122329.1 1387506 R 418136 CDS YP_001122330.1 134302361 4960316 1389111..1390193 1 NC_009257.1 YjgP/YjgQ permease 1390193 4960316 FTW_1485 Francisella tularensis subsp. tularensis WY96-3418 YjgP/YjgQ permease YP_001122330.1 1389111 D 418136 CDS YP_001122331.1 134302362 4960442 1390199..1391254 1 NC_009257.1 YjgP/YjgQ permease 1391254 4960442 FTW_1486 Francisella tularensis subsp. tularensis WY96-3418 YjgP/YjgQ permease YP_001122331.1 1390199 D 418136 CDS YP_001122332.1 134302363 4960241 1391262..1392515 1 NC_009257.1 M16 family metallopeptidase 1392515 4960241 FTW_1487 Francisella tularensis subsp. tularensis WY96-3418 M16 family metallopeptidase YP_001122332.1 1391262 D 418136 CDS YP_001122333.1 134302364 4958851 1392522..1393745 1 NC_009257.1 M16 family metallopeptidase 1393745 4958851 FTW_1488 Francisella tularensis subsp. tularensis WY96-3418 M16 family metallopeptidase YP_001122333.1 1392522 D 418136 CDS YP_001122334.1 134302365 4958803 1393746..1394324 1 NC_009257.1 putative methyltransferase family protein 1394324 4958803 FTW_1489 Francisella tularensis subsp. tularensis WY96-3418 putative methyltransferase family protein YP_001122334.1 1393746 D 418136 CDS YP_001122335.1 134302366 4958698 1394358..1395008 1 NC_009257.1 hypothetical protein 1395008 4958698 FTW_1490 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122335.1 1394358 D 418136 CDS YP_001122336.1 134302367 4958763 complement(1395061..1395672) 1 NC_009257.1 tRNA-(ms(2)io(6)a)-hydroxylase 1395672 4958763 FTW_1491 Francisella tularensis subsp. tularensis WY96-3418 tRNA-(ms(2)io(6)a)-hydroxylase YP_001122336.1 1395061 R 418136 CDS YP_001122337.1 134302368 4958895 1395788..1396591 1 NC_009257.1 uridine phosphorylase 1396591 4958895 FTW_1492 Francisella tularensis subsp. tularensis WY96-3418 uridine phosphorylase YP_001122337.1 1395788 D 418136 CDS YP_001122338.1 134302369 4958710 1396612..1397013 1 NC_009257.1 cytidine deaminase 1397013 cdd 4958710 cdd Francisella tularensis subsp. tularensis WY96-3418 cytidine deaminase YP_001122338.1 1396612 D 418136 CDS YP_001122339.1 134302370 4959573 complement(1397211..1400240) 1 NC_009257.1 FAD linked oxidase 1400240 4959573 FTW_1494 Francisella tularensis subsp. tularensis WY96-3418 FAD linked oxidase YP_001122339.1 1397211 R 418136 CDS YP_001122340.1 134302371 4958875 1400460..1401998 1 NC_009257.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 1401998 gpmI 4958875 gpmI Francisella tularensis subsp. tularensis WY96-3418 phosphoglyceromutase YP_001122340.1 1400460 D 418136 CDS YP_001122341.1 134302372 4960457 1402013..1403293 1 NC_009257.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1403293 serS 4960457 serS Francisella tularensis subsp. tularensis WY96-3418 seryl-tRNA synthetase YP_001122341.1 1402013 D 418136 CDS YP_001122342.1 134302373 4959423 1403403..1404302 1 NC_009257.1 ROK family protein 1404302 4959423 FTW_1497 Francisella tularensis subsp. tularensis WY96-3418 ROK family protein YP_001122342.1 1403403 D 418136 CDS YP_001122343.1 134302374 4959409 1404380..1405639 1 NC_009257.1 polysaccharide biosynthesis protein 1405639 4959409 FTW_1498 Francisella tularensis subsp. tularensis WY96-3418 polysaccharide biosynthesis protein YP_001122343.1 1404380 D 418136 CDS YP_001122344.1 134302375 4959316 complement(1405643..1405843) 1 NC_009257.1 hypothetical protein 1405843 4959316 FTW_1499 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122344.1 1405643 R 418136 CDS YP_001122345.1 134302376 4959107 complement(1405871..1406380) 1 NC_009257.1 hypothetical protein 1406380 4959107 FTW_1500 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122345.1 1405871 R 418136 CDS YP_001122346.1 134302377 4959229 1406757..1408538 1 NC_009257.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1408538 4959229 FTW_1501 Francisella tularensis subsp. tularensis WY96-3418 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_001122346.1 1406757 D 418136 CDS YP_001122347.1 134302378 4959215 1408535..1410184 1 NC_009257.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1410184 4959215 FTW_1502 Francisella tularensis subsp. tularensis WY96-3418 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_001122347.1 1408535 D 418136 CDS YP_001122348.1 134302379 4959256 complement(1410186..1411436) 1 NC_009257.1 dicarboxylate/amino acid:cation (Na+ or H+) symporter 1411436 4959256 FTW_1503 Francisella tularensis subsp. tularensis WY96-3418 dicarboxylate/amino acid:cation (Na+ or H+) symporter YP_001122348.1 1410186 R 418136 CDS YP_001122349.1 134302380 4959508 complement(1411575..1411955) 1 NC_009257.1 putative endoribonuclease L-PSP 1411955 4959508 FTW_1504 Francisella tularensis subsp. tularensis WY96-3418 putative endoribonuclease L-PSP YP_001122349.1 1411575 R 418136 CDS YP_001122350.1 134302381 4959565 complement(1411955..1413499) 1 NC_009257.1 sulfate permease family protein 1413499 4959565 FTW_1505 Francisella tularensis subsp. tularensis WY96-3418 sulfate permease family protein YP_001122350.1 1411955 R 418136 CDS YP_001122351.1 134302382 4959618 complement(1414459..1415577) 1 NC_009257.1 ABC -2 type transporter 1415577 4959618 FTW_1508 Francisella tularensis subsp. tularensis WY96-3418 ABC -2 type transporter YP_001122351.1 1414459 R 418136 CDS YP_001122352.1 134302383 4959838 complement(1415574..1416506) 1 NC_009257.1 ABC transporter ATP-binding protein 1416506 4959838 FTW_1509 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter ATP-binding protein YP_001122352.1 1415574 R 418136 CDS YP_001122353.1 134302384 4959953 1417591..1418619 1 NC_009257.1 glycerophosphoryl diester phosphodiesterase 1418619 4959953 FTW_1512 Francisella tularensis subsp. tularensis WY96-3418 glycerophosphoryl diester phosphodiesterase YP_001122353.1 1417591 D 418136 CDS YP_001122354.1 134302385 4959976 1418726..1420042 1 NC_009257.1 glycerol-3-phosphate transporter 1420042 glpT 4959976 glpT Francisella tularensis subsp. tularensis WY96-3418 glycerol-3-phosphate transporter YP_001122354.1 1418726 D 418136 CDS YP_001122355.1 134302386 4959983 1420058..1421452 1 NC_009257.1 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 1421452 dacB2 4959983 dacB2 Francisella tularensis subsp. tularensis WY96-3418 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase YP_001122355.1 1420058 D 418136 CDS YP_001122356.1 134302387 4959988 1421446..1422234 1 NC_009257.1 oxidoreductase, short-chain dehydrogenase/reductase 1422234 4959988 FTW_1515 Francisella tularensis subsp. tularensis WY96-3418 oxidoreductase, short-chain dehydrogenase/reductase YP_001122356.1 1421446 D 418136 CDS YP_001122357.1 134302388 4960038 join(1422525..1422854,1422854..1423405) 1 NC_009257.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. This gene contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' which permits frameshifting to produce a single ORF; programmed frameshift; transposase ISFtu1 1423405 4960038 FTW_1516 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122357.1 1422525 D 418136 CDS YP_001122358.1 134302389 4960054 1424174..1426399 1 NC_009257.1 catalase/peroxidase HPI 1426399 katG 4960054 katG Francisella tularensis subsp. tularensis WY96-3418 catalase/peroxidase HPI YP_001122358.1 1424174 D 418136 CDS YP_001122359.1 134302390 4960079 1426504..1427829 1 NC_009257.1 dGTP triphosphohydrolase 1427829 dgt 4960079 dgt Francisella tularensis subsp. tularensis WY96-3418 dGTP triphosphohydrolase YP_001122359.1 1426504 D 418136 CDS YP_001122360.1 134302391 4960095 complement(1427813..1429033) 1 NC_009257.1 major facilitator transporter 1429033 4960095 FTW_1520 Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001122360.1 1427813 R 418136 CDS YP_001122361.1 134302392 4960099 complement(1429093..1429437) 1 NC_009257.1 hypothetical protein 1429437 4960099 FTW_1521 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122361.1 1429093 R 418136 CDS YP_001122362.1 134302393 4959464 complement(1430445..1431074) 1 NC_009257.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 1431074 upp 4959464 upp Francisella tularensis subsp. tularensis WY96-3418 uracil phosphoribosyltransferase YP_001122362.1 1430445 R 418136 CDS YP_001122363.1 134302394 4960276 1434319..1435515 1 NC_009257.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 1435515 kbl 4960276 kbl Francisella tularensis subsp. tularensis WY96-3418 2-amino-3-ketobutyrate coenzyme A ligase YP_001122363.1 1434319 D 418136 CDS YP_001122364.1 134302395 4959117 1435538..1436593 1 NC_009257.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 1436593 tdh 4959117 tdh Francisella tularensis subsp. tularensis WY96-3418 L-threonine 3-dehydrogenase YP_001122364.1 1435538 D 418136 CDS YP_001122365.1 134302396 4959328 1436595..1437857 1 NC_009257.1 hypothetical protein 1437857 4959328 FTW_1529 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122365.1 1436595 D 418136 CDS YP_001122366.1 134302397 4958701 complement(1437862..1438551) 1 NC_009257.1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1438551 ispD 4958701 ispD Francisella tularensis subsp. tularensis WY96-3418 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_001122366.1 1437862 R 418136 CDS YP_001122367.1 134302398 4959301 complement(1438541..1438831) 1 NC_009257.1 cell division protein; COG2919; contain pfam profile PF04977:Septum formation initiator; putative septum formation initiator 1438831 4959301 FTW_1531 Francisella tularensis subsp. tularensis WY96-3418 putative septum formation initiator YP_001122367.1 1438541 R 418136 CDS YP_001122368.1 134302399 4959319 complement(1438839..1440209) 1 NC_009257.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1440209 eno 4959319 eno Francisella tularensis subsp. tularensis WY96-3418 phosphopyruvate hydratase YP_001122368.1 1438839 R 418136 CDS YP_001122369.1 134302400 4959138 complement(1440318..1441571) 1 NC_009257.1 major facilitator transporter 1441571 4959138 FTW_1533 Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001122369.1 1440318 R 418136 CDS YP_001122370.1 134302401 4960197 complement(1441659..1442423) 1 NC_009257.1 nicotinamide mononucleotide transporter 1442423 pnuC3 4960197 pnuC3 Francisella tularensis subsp. tularensis WY96-3418 nicotinamide mononucleotide transporter YP_001122370.1 1441659 R 418136 CDS YP_001122371.1 134302680 4960215 complement(1443374..1444339) 1 NC_009257.1 ROK family glucokinase 1444339 4960215 FTW_2105 Francisella tularensis subsp. tularensis WY96-3418 ROK family glucokinase YP_001122371.1 1443374 R 418136 CDS YP_001122372.1 134302402 4960523 complement(1444349..1445698) 1 NC_009257.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 1445698 rumA 4960523 rumA Francisella tularensis subsp. tularensis WY96-3418 23S rRNA 5-methyluridine methyltransferase YP_001122372.1 1444349 R 418136 CDS YP_001122373.1 134302403 4960257 complement(1445787..1446359) 1 NC_009257.1 hypothetical protein 1446359 4960257 FTW_1539 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122373.1 1445787 R 418136 CDS YP_001122374.1 134302404 4959694 complement(1446624..1446842) 1 NC_009257.1 Contains equivalog HMM TIGR00690: DNA-directed RNA polymerase, omega subunit; DNA-directed RNA polymerase subunit omega 1446842 rpoZ 4959694 rpoZ Francisella tularensis subsp. tularensis WY96-3418 DNA-directed RNA polymerase subunit omega YP_001122374.1 1446624 R 418136 CDS YP_001122375.1 134302405 4960299 complement(1446835..1447500) 1 NC_009257.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1447500 udk 4960299 udk Francisella tularensis subsp. tularensis WY96-3418 uridine kinase YP_001122375.1 1446835 R 418136 CDS YP_001122376.1 134302406 4960410 complement(1447511..1448359) 1 NC_009257.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1448359 kdsA 4960410 kdsA Francisella tularensis subsp. tularensis WY96-3418 2-dehydro-3-deoxyphosphooctonate aldolase YP_001122376.1 1447511 R 418136 CDS YP_001122377.1 134302407 4960441 complement(1448369..1448719) 1 NC_009257.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 1448719 4960441 FTW_1543 Francisella tularensis subsp. tularensis WY96-3418 iron-sulfur cluster insertion protein ErpA YP_001122377.1 1448369 R 418136 CDS YP_001122378.1 134302408 4958990 complement(1448725..1450806) 1 NC_009257.1 Similar to RNA binding S1:KH [Halorhodospira halophila SL1] GI:88948524 and Polyribonucleotide nucleotidyltransferase [Nitrococcus mobilis Nb-231] GI:88812956; polynucleotide phosphorylase/polyadenylase 1450806 4958990 FTW_1544 Francisella tularensis subsp. tularensis WY96-3418 polynucleotide phosphorylase/polyadenylase YP_001122378.1 1448725 R 418136 CDS YP_001122379.1 134302409 4959399 complement(1450863..1451129) 1 NC_009257.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1451129 rpsO 4959399 rpsO Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S15 YP_001122379.1 1450863 R 418136 CDS YP_001122380.1 134302410 4958863 complement(1451235..1452929) 1 NC_009257.1 Similar to Peptidoglycan glycosyltransferase [Oceanospirillum sp. MED92](GI:89095265) that has experimental mRNA evidence; putative peptidoglycan glycosyltransferase 1452929 4958863 FTW_1546 Francisella tularensis subsp. tularensis WY96-3418 putative peptidoglycan glycosyltransferase YP_001122380.1 1451235 R 418136 CDS YP_001122381.1 134302411 4959612 complement(1452922..1453269) 1 NC_009257.1 Contains TIGR equivalog HMM TIGR02209: cell division protein FtsL; cell division protein FtsL 1453269 ftsL 4959612 ftsL Francisella tularensis subsp. tularensis WY96-3418 cell division protein FtsL YP_001122381.1 1452922 R 418136 CDS YP_001122382.1 134302412 4959019 complement(1453269..1454168) 1 NC_009257.1 Contains TIGR equivalog HMM TIGR00006: S-adenosyl-methyltransferase MraW; S-adenosyl-methyltransferase MraW 1454168 mraW 4959019 mraW Francisella tularensis subsp. tularensis WY96-3418 S-adenosyl-methyltransferase MraW YP_001122382.1 1453269 R 418136 CDS YP_001122383.1 134302413 4959408 complement(1454192..1456291) 1 NC_009257.1 Contains HMM profile PF00501: AMP-binding enzyme. Similar to 2-acyl-glycerophospho-ethanolamine acyltransferase [Oceanospirillum sp. MED92](GI:89092511) that has experiment mRNA evidence; AMP binding protein 1456291 4959408 FTW_1549 Francisella tularensis subsp. tularensis WY96-3418 AMP binding protein YP_001122383.1 1454192 R 418136 CDS YP_001122384.1 134302414 4958952 1456385..1457209 1 NC_009257.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 1457209 mutM 4958952 mutM Francisella tularensis subsp. tularensis WY96-3418 formamidopyrimidine-DNA glycosylase YP_001122384.1 1456385 D 418136 CDS YP_001122385.1 134302415 4959046 join(1457280..1457609,1457609..1458160) 1 NC_009257.1 This gene contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' which permits frameshifting to produce a single ORF; programmed frameshift; transposase ISFtu1 1458160 4959046 FTW_1551 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122385.1 1457280 D 418136 CDS YP_001122386.1 134302416 4959023 complement(1458168..1458707) 1 NC_009257.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 1458707 4959023 FTW_1553 Francisella tularensis subsp. tularensis WY96-3418 glutamine amidotransferase subunit PdxT YP_001122386.1 1458168 R 418136 CDS YP_001122387.1 134302417 4959082 complement(1458710..1459573) 1 NC_009257.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 1459573 4959082 FTW_1554 Francisella tularensis subsp. tularensis WY96-3418 pyridoxal biosynthesis lyase PdxS YP_001122387.1 1458710 R 418136 CDS YP_001122388.1 134302418 4958728 complement(1459703..1462114) 1 NC_009257.1 Contains equivalog HMM TIGR01059: DNA gyrase, B subunit; DNA gyrase subunit B 1462114 gyrB 4958728 gyrB Francisella tularensis subsp. tularensis WY96-3418 DNA gyrase subunit B YP_001122388.1 1459703 R 418136 CDS YP_001122389.1 134302419 4959031 1462314..1463096 1 NC_009257.1 hypothetical protein 1463096 4959031 FTW_1556 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122389.1 1462314 D 418136 CDS YP_001122390.1 134302420 4960455 1463130..1464113 1 NC_009257.1 Contains HMM profile PF01207: Dihydrouridine synthase (Dus). Similar to tRNA-dihydrouridine synthase A [Escherichia coli K12]GI:16131875; tRNA-dihydrouridine synthase A 1464113 4960455 FTW_1557 Francisella tularensis subsp. tularensis WY96-3418 tRNA-dihydrouridine synthase A YP_001122390.1 1463130 D 418136 CDS YP_001122391.1 134302421 4960415 complement(1464120..1464887) 1 NC_009257.1 Mapped to COG1651: Protein-disulfide isomerase; putative protein disulfide isomerase 1464887 4960415 FTW_1558 Francisella tularensis subsp. tularensis WY96-3418 putative protein disulfide isomerase YP_001122391.1 1464120 R 418136 CDS YP_001122392.1 134302422 4959535 complement(1465377..1465625) 1 NC_009257.1 hypothetical protein 1465625 4959535 FTW_1559 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122392.1 1465377 R 418136 CDS YP_001122393.1 134302423 4960008 complement(1465868..1467781) 1 NC_009257.1 hypothetical protein 1467781 4960008 FTW_1560 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122393.1 1465868 R 418136 CDS YP_001122394.1 134302424 4959939 1467951..1469114 1 NC_009257.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1469114 sucC 4959939 sucC Francisella tularensis subsp. tularensis WY96-3418 succinyl-CoA synthetase subunit beta YP_001122394.1 1467951 D 418136 CDS YP_001122395.1 134302425 4959883 1469146..1470018 1 NC_009257.1 Contains subfamily HMM TIGR01019: succinyl-CoA synthetase, alpha subunit; succinyl-CoA synthetase, alpha subunit 1470018 sucA2 4959883 sucA2 Francisella tularensis subsp. tularensis WY96-3418 succinyl-CoA synthetase, alpha subunit YP_001122395.1 1469146 D 418136 CDS YP_001122396.1 134302426 4959728 1470130..1470555 1 NC_009257.1 hypothetical protein 1470555 4959728 FTW_1563 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122396.1 1470130 D 418136 CDS YP_001122397.1 134302427 4960494 1470954..1471979 1 NC_009257.1 hypothetical protein 1471979 4960494 FTW_1565 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122397.1 1470954 D 418136 CDS YP_001122398.1 134302428 4959241 complement(1472111..1473328) 1 NC_009257.1 hypothetical protein 1473328 4959241 FTW_1566 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122398.1 1472111 R 418136 CDS YP_001122399.1 134302429 4959427 complement(1475921..1476685) 1 NC_009257.1 hypothetical protein 1476685 4959427 FTW_1571 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122399.1 1475921 R 418136 CDS YP_001122400.1 134302430 4959016 1477527..1478249 1 NC_009257.1 Contains PFAM profile PF03932: CutC family; putative copper transport (CutC) family protein 1478249 4959016 FTW_1574 Francisella tularensis subsp. tularensis WY96-3418 putative copper transport (CutC) family protein YP_001122400.1 1477527 D 418136 CDS YP_001122401.1 134302431 4960155 1479544..1480470 1 NC_009257.1 Contains Pfam profiles PF03466: LysR substrate binding domain and PF00126: transcriptional regulator, LysR family. Map to COG0583 Transcriptional regulator; LysR family transcriptional regulator 1480470 4960155 FTW_1577 Francisella tularensis subsp. tularensis WY96-3418 LysR family transcriptional regulator YP_001122401.1 1479544 D 418136 CDS YP_001122402.1 134302432 4959014 1480526..1481185 1 NC_009257.1 phosphoglycolate phosphatase 1481185 gph 4959014 gph Francisella tularensis subsp. tularensis WY96-3418 phosphoglycolate phosphatase YP_001122402.1 1480526 D 418136 CDS YP_001122403.1 134302433 4958933 1481228..1482445 1 NC_009257.1 putative phospholipase D family protein 1482445 4958933 FTW_1579 Francisella tularensis subsp. tularensis WY96-3418 putative phospholipase D family protein YP_001122403.1 1481228 D 418136 CDS YP_001122404.1 134302434 4959151 1482537..1483487 1 NC_009257.1 Contains TIGR equivalog HMM TIGR01292: thioredoxin-disulfide reductase; thioredoxin reductase 1483487 trxB 4959151 trxB Francisella tularensis subsp. tularensis WY96-3418 thioredoxin reductase YP_001122404.1 1482537 D 418136 CDS YP_001122405.1 134302435 4959433 1483595..1484761 1 NC_009257.1 hypothetical protein 1484761 4959433 FTW_1581 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122405.1 1483595 D 418136 CDS YP_001122406.1 134302436 4958720 complement(1485859..1487661) 1 NC_009257.1 Contains TIGR superfamily HMM TIGR00585: DNA mismatch repair protein MutL; DNA mismatch repair protein 1487661 mutL 4958720 mutL Francisella tularensis subsp. tularensis WY96-3418 DNA mismatch repair protein YP_001122406.1 1485859 R 418136 CDS YP_001122407.1 134302437 4958715 complement(1487669..1488331) 1 NC_009257.1 hypothetical protein 1488331 4958715 FTW_1585 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122407.1 1487669 R 418136 CDS YP_001122408.1 134302438 4958834 complement(1488399..1489118) 1 NC_009257.1 hypothetical protein 1489118 4958834 FTW_1586 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122408.1 1488399 R 418136 CDS YP_001122409.1 134302439 4958953 1489272..1490159 1 NC_009257.1 Contains equivalog HMM TIGR00157: ribosome small subunit-dependent GTPase A; ribosome small subunit-dependent GTPase A 1490159 rsgA 4958953 rsgA Francisella tularensis subsp. tularensis WY96-3418 ribosome small subunit-dependent GTPase A YP_001122409.1 1489272 D 418136 CDS YP_001122410.1 134302440 4959429 1490378..1491193 1 NC_009257.1 lipoprotein 1491193 4959429 FTW_1588 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001122410.1 1490378 D 418136 CDS YP_001122411.1 134302441 4959293 complement(1491446..1492588) 1 NC_009257.1 Mapped to COG0687 Spermidine/putrescine-binding periplasmic protein; hypothetical protein 1492588 4959293 FTW_1589 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122411.1 1491446 R 418136 CDS YP_001122412.1 134302442 4958794 1492711..1494120 1 NC_009257.1 hypothetical protein 1494120 4958794 FTW_1590 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122412.1 1492711 D 418136 CDS YP_001122413.1 134302443 4959530 1494222..1495328 1 NC_009257.1 PerM family protein 1495328 4959530 FTW_1591 Francisella tularensis subsp. tularensis WY96-3418 PerM family protein YP_001122413.1 1494222 D 418136 CDS YP_001122414.1 134302444 4959511 1495322..1497064 1 NC_009257.1 Mapped to equivalog HMM TIGR00644: single-stranded-DNA-specific exonuclease; single-stranded-DNA-specific exonuclease RecJ 1497064 recJ 4959511 recJ Francisella tularensis subsp. tularensis WY96-3418 single-stranded-DNA-specific exonuclease RecJ YP_001122414.1 1495322 D 418136 CDS YP_001122415.1 134302445 4959536 1497061..1497843 1 NC_009257.1 Contains equivalog domain HMM TIGR00121: biotin-[acetyl-CoA-carboxylase] ligase. Maps to COG0340 Biotin-(acetyl-CoA carboxylase) ligase; biotin--acetyl-CoA-carboxylase ligase 1497843 4959536 FTW_1593 Francisella tularensis subsp. tularensis WY96-3418 biotin--acetyl-CoA-carboxylase ligase YP_001122415.1 1497061 D 418136 CDS YP_001122416.1 134302446 4959538 1497840..1498763 1 NC_009257.1 Contains hypoth_equivalog HMM TIGR00462: lysyl-tRNA synthetase homolog GenX. Maps to COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II); tRNA synthetase 1498763 4959538 FTW_1594 Francisella tularensis subsp. tularensis WY96-3418 tRNA synthetase YP_001122416.1 1497840 D 418136 CDS YP_001122417.1 134302447 4959537 complement(1498768..1499700) 1 NC_009257.1 Contains pfam profile PF00924: transporter, small conductance mechanosensitive ion channel (MscS) family. Maps to COG0668 Small-conductance mechanosensitive channel; small conductance mechanosensitive ion channel protein 1499700 4959537 FTW_1595 Francisella tularensis subsp. tularensis WY96-3418 small conductance mechanosensitive ion channel protein YP_001122417.1 1498768 R 418136 CDS YP_001122418.1 134302448 4959540 complement(1499912..1500592) 1 NC_009257.1 hypothetical protein 1500592 4959540 FTW_1596 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122418.1 1499912 R 418136 CDS YP_001122419.1 134302449 4959541 complement(1500686..1502041) 1 NC_009257.1 Maps to equivalog HMM TIGR00514: acetyl-CoA carboxylase, biotin carboxylase. Maps to COG0439 Biotin carboxylase; acetyl-CoA carboxylase, biotin carboxylase 1502041 accC 4959541 accC Francisella tularensis subsp. tularensis WY96-3418 acetyl-CoA carboxylase, biotin carboxylase YP_001122419.1 1500686 R 418136 CDS YP_001122420.1 134302450 4959542 complement(1502106..1502579) 1 NC_009257.1 Maps to equivalog HMM TIGR00531: acetyl-CoA carboxylase, biotin carboxyl carrier protein. Maps to COG0511 Biotin carboxyl carrier protein; acetyl-CoA carboxylase, biotin carboxyl carrier protein 1502579 accB 4959542 accB Francisella tularensis subsp. tularensis WY96-3418 acetyl-CoA carboxylase, biotin carboxyl carrier protein YP_001122420.1 1502106 R 418136 CDS YP_001122421.1 134302451 4959543 complement(1502584..1503021) 1 NC_009257.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 1503021 aroQ 4959543 aroQ Francisella tularensis subsp. tularensis WY96-3418 3-dehydroquinate dehydratase YP_001122421.1 1502584 R 418136 CDS YP_001122422.1 134302452 4959544 complement(1503025..1503852) 1 NC_009257.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 1503852 apaH 4959544 apaH Francisella tularensis subsp. tularensis WY96-3418 diadenosine tetraphosphatase YP_001122422.1 1503025 R 418136 CDS YP_001122423.1 134302453 4959545 complement(1503864..1504652) 1 NC_009257.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1504652 ksgA 4959545 ksgA Francisella tularensis subsp. tularensis WY96-3418 dimethyladenosine transferase YP_001122423.1 1503864 R 418136 CDS YP_001122424.1 134302454 4959548 complement(1504654..1506057) 1 NC_009257.1 hypothetical protein 1506057 4959548 FTW_1602 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122424.1 1504654 R 418136 CDS YP_001122425.1 134302455 4959549 complement(1506057..1508663) 1 NC_009257.1 Contains Pfam profile PF04453: Organic solvent tolerance protein. Maps to COG1452 Organic solvent tolerance protein OstA; organic solvent tolerance protein 1508663 4959549 FTW_1603 Francisella tularensis subsp. tularensis WY96-3418 organic solvent tolerance protein YP_001122425.1 1506057 R 418136 CDS YP_001122426.1 134302456 4959550 1508789..1510534 1 NC_009257.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1510534 argS 4959550 argS Francisella tularensis subsp. tularensis WY96-3418 arginyl-tRNA synthetase YP_001122426.1 1508789 D 418136 CDS YP_001122427.1 134302457 4959554 complement(1510586..1511005) 1 NC_009257.1 lipoprotein 1511005 4959554 FTW_1605 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein YP_001122427.1 1510586 R 418136 CDS YP_001122428.1 134302458 4959553 complement(1511498..1512559) 1 NC_009257.1 Maps to subfamily HMM TIGR00520: L-asparaginases, type II; type II L-asparaginase 1512559 ansB 4959553 ansB Francisella tularensis subsp. tularensis WY96-3418 type II L-asparaginase YP_001122428.1 1511498 R 418136 CDS YP_001122429.1 134302459 4959516 complement(1512677..1513144) 1 NC_009257.1 RNA methyltransferase 1513144 4959516 FTW_1607 Francisella tularensis subsp. tularensis WY96-3418 RNA methyltransferase YP_001122429.1 1512677 R 418136 CDS YP_001122430.1 134302460 4959582 complement(1513148..1514122) 1 NC_009257.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 1514122 hemB 4959582 hemB Francisella tularensis subsp. tularensis WY96-3418 delta-aminolevulinic acid dehydratase YP_001122430.1 1513148 R 418136 CDS YP_001122431.1 134302461 4959575 complement(1514130..1514408) 1 NC_009257.1 Maps to COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein; RNA-binding protein 1514408 4959575 FTW_1609 Francisella tularensis subsp. tularensis WY96-3418 RNA-binding protein YP_001122431.1 1514130 R 418136 CDS YP_001122432.1 134302462 4959708 complement(1514419..1515330) 1 NC_009257.1 DNA polymerase III, delta prime subunit 1515330 4959708 FTW_1610 Francisella tularensis subsp. tularensis WY96-3418 DNA polymerase III, delta prime subunit YP_001122432.1 1514419 R 418136 CDS YP_001122433.1 134302463 4958722 complement(1515338..1516354) 1 NC_009257.1 SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 1516354 4958722 FTW_1611 Francisella tularensis subsp. tularensis WY96-3418 putative periplasmic protease YP_001122433.1 1515338 R 418136 CDS YP_001122434.1 134302464 4960449 complement(1516366..1516995) 1 NC_009257.1 glutathione S-transferase 1516995 4960449 FTW_1612 Francisella tularensis subsp. tularensis WY96-3418 glutathione S-transferase YP_001122434.1 1516366 R 418136 CDS YP_001122435.1 134302465 4959786 1517084..1517398 1 NC_009257.1 Maps to pfam profile PF04358: DsrC like protein; putative DsrC like protein 1517398 4959786 FTW_1613 Francisella tularensis subsp. tularensis WY96-3418 putative DsrC like protein YP_001122435.1 1517084 D 418136 CDS YP_001122436.1 134302466 4959756 1517389..1517682 1 NC_009257.1 Maps to pfam profile PF04362: Protein of unknown function (DUF495), this is a family of bacterial Fe(2+) trafficking proteins; hypothetical protein 1517682 4959756 FTW_1614 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122436.1 1517389 D 418136 CDS YP_001122437.1 134302467 4959214 1517774..1519537 1 NC_009257.1 Maps to pfam profile PF02366: dolichyl-phosphate-mannose-protein mannosyltransferase; dolichyl-phosphate-mannose-protein mannosyltransferase family protein 1519537 4959214 FTW_1615 Francisella tularensis subsp. tularensis WY96-3418 dolichyl-phosphate-mannose-protein mannosyltransferase family protein YP_001122437.1 1517774 D 418136 CDS YP_001122438.1 134302468 4959845 complement(1519929..1520882) 1 NC_009257.1 Maps to pfam profile PF00535: glycosyl transferase, group 2 family protein; putative glucosyl transferase, group 2 family protein 1520882 4959845 FTW_1616 Francisella tularensis subsp. tularensis WY96-3418 putative glucosyl transferase, group 2 family protein YP_001122438.1 1519929 R 418136 CDS YP_001122439.1 134302469 4959909 1520984..1521790 1 NC_009257.1 Maps to pfam profile PF04794: YdjC-like protein. This region is possibly involved in the the cleavage of cellobiose-phosphate; hypothetical protein 1521790 4959909 FTW_1617 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122439.1 1520984 D 418136 CDS YP_001122440.1 134302470 4959940 complement(1521798..1523003) 1 NC_009257.1 Maps to equivalog HMM TIGR02614: cell division protein FtsW; cell division protein FtsW 1523003 ftsW 4959940 ftsW Francisella tularensis subsp. tularensis WY96-3418 cell division protein FtsW YP_001122440.1 1521798 R 418136 CDS YP_001122441.1 134302471 4959969 complement(1523013..1524263) 1 NC_009257.1 Maps to equivalog HMM TIGR01087: UDP-N-acetylmuramoylalanine--D-glutamate ligase; UDP-N-acetylmuramoylalanine--D-glutamate ligase 1524263 murD 4959969 murD Francisella tularensis subsp. tularensis WY96-3418 UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_001122441.1 1523013 R 418136 CDS YP_001122442.1 134302472 4959990 complement(1524263..1525360) 1 NC_009257.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1525360 mraY 4959990 mraY Francisella tularensis subsp. tularensis WY96-3418 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001122442.1 1524263 R 418136 CDS YP_001122443.1 134302473 4959977 complement(1525435..1527027) 1 NC_009257.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 1527027 pckA 4959977 pckA Francisella tularensis subsp. tularensis WY96-3418 phosphoenolpyruvate carboxykinase YP_001122443.1 1525435 R 418136 CDS YP_001122444.1 134302474 4960002 1527172..1528818 1 NC_009257.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 1528818 glnS 4960002 glnS Francisella tularensis subsp. tularensis WY96-3418 glutaminyl-tRNA synthetase YP_001122444.1 1527172 D 418136 CDS YP_001122445.1 134302475 4960005 1528839..1530299 1 NC_009257.1 hypothetical protein 1530299 4960005 FTW_1623 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122445.1 1528839 D 418136 CDS YP_001122446.1 134302476 4959422 complement(1531785..1533626) 1 NC_009257.1 Maps to pfam profile PF00005: ABC transporter, ATP-binding protein; ABC transporter ATP-binding protein 1533626 4959422 FTW_1626 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter ATP-binding protein YP_001122446.1 1531785 R 418136 CDS YP_001122447.1 134302477 4960003 complement(1533660..1534886) 1 NC_009257.1 Maps to pfam profile PF07690: transporter, major facilitator family. Also maps to COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily transporter 1534886 4960003 FTW_1627 Francisella tularensis subsp. tularensis WY96-3418 major facilitator superfamily transporter YP_001122447.1 1533660 R 418136 CDS YP_001122448.1 134302478 4960028 complement(1534969..1536012) 1 NC_009257.1 hypothetical protein 1536012 4960028 FTW_1628 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122448.1 1534969 R 418136 CDS YP_001122449.1 134302479 4958747 1536284..1537477 1 NC_009257.1 Maps to subfamily HMM TIGR00710: drug resistance transporter, Bcr/CflA subfamily; drug resistance transporter, Bcr/CflA subfamily protein 1537477 4958747 FTW_1629 Francisella tularensis subsp. tularensis WY96-3418 drug resistance transporter, Bcr/CflA subfamily protein YP_001122449.1 1536284 D 418136 CDS YP_001122450.1 134302480 4960044 1537507..1538151 1 NC_009257.1 hypothetical protein 1538151 4960044 FTW_1630 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122450.1 1537507 D 418136 CDS YP_001122451.1 134302481 4960072 join(1538349..1538678,1538678..1539229) 1 NC_009257.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. This gene contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' which permits frameshifting to produce a single ORF; programmed frameshift; transposase ISFtu1 1539229 4960072 FTW_1632 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122451.1 1538349 D 418136 CDS YP_001122452.1 134302482 4959007 complement(1539860..1541230) 1 NC_009257.1 Maps to equivalog HMM TIGR01081: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 1541230 mpl 4959007 mpl Francisella tularensis subsp. tularensis WY96-3418 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_001122452.1 1539860 R 418136 CDS YP_001122453.1 134302483 4960150 1541390..1542016 1 NC_009257.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1542016 pyrE 4960150 pyrE Francisella tularensis subsp. tularensis WY96-3418 orotate phosphoribosyltransferase YP_001122453.1 1541390 D 418136 CDS YP_001122454.1 134302484 4960151 1542006..1542722 1 NC_009257.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 1542722 lpxH 4960151 lpxH Francisella tularensis subsp. tularensis WY96-3418 UDP-2,3-diacylglucosamine hydrolase YP_001122454.1 1542006 D 418136 CDS YP_001122455.1 134302485 4960152 complement(1542739..1543599) 1 NC_009257.1 Maps to HMM profile PF00795: hydrolase, carbon-nitrogen family; carbon-nitrogen hydrolase family protein 1543599 4960152 FTW_1638 Francisella tularensis subsp. tularensis WY96-3418 carbon-nitrogen hydrolase family protein YP_001122455.1 1542739 R 418136 CDS YP_001122456.1 134302486 4960153 complement(1543601..1544587) 1 NC_009257.1 Maps to pfam profile PF04371: Porphyromonas-type peptidyl-arginine deiminase; peptidyl-arginine deiminase 1544587 4960153 FTW_1639 Francisella tularensis subsp. tularensis WY96-3418 peptidyl-arginine deiminase YP_001122456.1 1543601 R 418136 CDS YP_001122457.1 134302487 4958833 complement(1546242..1547111) 1 NC_009257.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 1547111 speE 4958833 speE Francisella tularensis subsp. tularensis WY96-3418 spermidine synthase YP_001122457.1 1546242 R 418136 CDS YP_001122458.1 134302488 4960179 complement(1547111..1547599) 1 NC_009257.1 Maps to pfam profile PF02675: S-adenosylmethionine decarboxylase; S-adenosylmethionine decarboxylase 1547599 4960179 FTW_1644 Francisella tularensis subsp. tularensis WY96-3418 S-adenosylmethionine decarboxylase YP_001122458.1 1547111 R 418136 CDS YP_001122459.1 134302489 4960127 1547855..1548085 1 NC_009257.1 hypothetical protein 1548085 4960127 FTW_1645 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122459.1 1547855 D 418136 CDS YP_001122460.1 134302490 4959435 complement(1548164..1549399) 1 NC_009257.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1549399 thrC 4959435 thrC Francisella tularensis subsp. tularensis WY96-3418 threonine synthase YP_001122460.1 1548164 R 418136 CDS YP_001122461.1 134302491 4960198 complement(1549412..1550365) 1 NC_009257.1 Maps to equivalog HMM TIGR00191: homoserine kinase; homoserine kinase 1550365 thrB 4960198 thrB Francisella tularensis subsp. tularensis WY96-3418 homoserine kinase YP_001122461.1 1549412 R 418136 CDS YP_001122462.1 134302492 4960200 complement(1550368..1552788) 1 NC_009257.1 bifunctional aspartokinase/homoserine dehydrogenase 1552788 4960200 FTW_1648 Francisella tularensis subsp. tularensis WY96-3418 bifunctional aspartokinase/homoserine dehydrogenase YP_001122462.1 1550368 R 418136 CDS YP_001122463.1 134302493 4960202 1552884..1553984 1 NC_009257.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1553984 asd 4960202 asd Francisella tularensis subsp. tularensis WY96-3418 aspartate-semialdehyde dehydrogenase YP_001122463.1 1552884 D 418136 CDS YP_001122464.1 134302494 4960214 complement(1553958..1554851) 1 NC_009257.1 hypothetical protein 1554851 4960214 FTW_1650 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122464.1 1553958 R 418136 CDS YP_001122465.1 134302495 4959430 complement(1554860..1556218) 1 NC_009257.1 Maps to subfamily HMM profile TIGR01143: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; UDP-N--acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase 1556218 murF 4959430 murF Francisella tularensis subsp. tularensis WY96-3418 UDP-N--acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase YP_001122465.1 1554860 R 418136 CDS YP_001122466.1 134302496 4960228 complement(1556571..1556960) 1 NC_009257.1 hypothetical protein 1556960 4960228 FTW_1652 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122466.1 1556571 R 418136 CDS YP_001122467.1 134302497 4960229 complement(1557011..1558450) 1 NC_009257.1 Maps to subfamily HMM profile TIGR01085: UDP-N-acetylmuramyl-tripeptide synthetases; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1558450 murE 4960229 murE Francisella tularensis subsp. tularensis WY96-3418 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_001122467.1 1557011 R 418136 CDS YP_001122468.1 134302498 4960238 complement(1558661..1559551) 1 NC_009257.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1559551 glyQ 4960238 glyQ Francisella tularensis subsp. tularensis WY96-3418 glycyl-tRNA synthetase subunit alpha YP_001122468.1 1558661 R 418136 CDS YP_001122469.1 134302499 4960254 complement(1559643..1561106) 1 NC_009257.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 1561106 malQ 4960254 malQ Francisella tularensis subsp. tularensis WY96-3418 4-alpha-glucanotransferase YP_001122469.1 1559643 R 418136 CDS YP_001122470.1 134302500 4960265 complement(1561150..1563423) 1 NC_009257.1 glycogen/starch/alpha-glucan phosphorylase 1563423 glgP 4960265 glgP Francisella tularensis subsp. tularensis WY96-3418 glycogen/starch/alpha-glucan phosphorylase YP_001122470.1 1561150 R 418136 CDS YP_001122471.1 134302501 4960315 complement(1563528..1564997) 1 NC_009257.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 1564997 glgA 4960315 glgA Francisella tularensis subsp. tularensis WY96-3418 glycogen synthase YP_001122471.1 1563528 R 418136 CDS YP_001122472.1 134302502 4960275 complement(1565007..1566278) 1 NC_009257.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1566278 glgC 4960275 glgC Francisella tularensis subsp. tularensis WY96-3418 glucose-1-phosphate adenylyltransferase YP_001122472.1 1565007 R 418136 CDS YP_001122473.1 134302503 4960443 complement(1566312..1567946) 1 NC_009257.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 1567946 4960443 FTW_1659 Francisella tularensis subsp. tularensis WY96-3418 phosphoglucomutase YP_001122473.1 1566312 R 418136 CDS YP_001122474.1 134302504 4960446 1568248..1570170 1 NC_009257.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 1570170 glgB 4960446 glgB Francisella tularensis subsp. tularensis WY96-3418 glycogen branching protein YP_001122474.1 1568248 D 418136 CDS YP_001122475.1 134302505 4960039 1570204..1573416 1 NC_009257.1 pullulonase, type I 1573416 pulA 4960039 pulA Francisella tularensis subsp. tularensis WY96-3418 pullulonase, type I YP_001122475.1 1570204 D 418136 CDS YP_001122476.1 134302506 4960023 1573442..1574287 1 NC_009257.1 shikimate / quinate 5-dehydrogenase 1574287 4960023 FTW_1662 Francisella tularensis subsp. tularensis WY96-3418 shikimate / quinate 5-dehydrogenase YP_001122476.1 1573442 D 418136 CDS YP_001122477.1 134302507 4958979 complement(1574407..1575852) 1 NC_009257.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 1575852 gcvP2 4958979 gcvP2 Francisella tularensis subsp. tularensis WY96-3418 glycine dehydrogenase subunit 2 YP_001122477.1 1574407 R 418136 CDS YP_001122478.1 134302508 4960158 complement(1575858..1577225) 1 NC_009257.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 1577225 gcvP1 4960158 gcvP1 Francisella tularensis subsp. tularensis WY96-3418 glycine dehydrogenase subunit 1 YP_001122478.1 1575858 R 418136 CDS YP_001122479.1 134302509 4959171 complement(1577290..1577673) 1 NC_009257.1 glycine cleavage system H protein 1577673 gcvH2 4959171 gcvH2 Francisella tularensis subsp. tularensis WY96-3418 glycine cleavage system H protein YP_001122479.1 1577290 R 418136 CDS YP_001122480.1 134302510 4958917 complement(1577730..1578806) 1 NC_009257.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 1578806 gcvT 4958917 gcvT Francisella tularensis subsp. tularensis WY96-3418 glycine cleavage system aminomethyltransferase T YP_001122480.1 1577730 R 418136 CDS YP_001122481.1 134302511 4959284 complement(1578897..1581038) 1 NC_009257.1 Lys decarboxylase 1581038 cadA 4959284 cadA Francisella tularensis subsp. tularensis WY96-3418 Lys decarboxylase YP_001122481.1 1578897 R 418136 CDS YP_001122482.1 134302512 4959688 complement(1581155..1581850) 1 NC_009257.1 pfam03550; lipoprotein releasing ABC transporter ATP-binding protein 1581850 lolB1 4959688 lolB1 Francisella tularensis subsp. tularensis WY96-3418 lipoprotein releasing ABC transporter ATP-binding protein YP_001122482.1 1581155 R 418136 CDS YP_001122483.1 134302513 4959719 complement(1581843..1583105) 1 NC_009257.1 LolC/E family lipoprotein releasing system ABC transporter transmembrane protein 1583105 lolC 4959719 lolC Francisella tularensis subsp. tularensis WY96-3418 LolC/E family lipoprotein releasing system ABC transporter transmembrane protein YP_001122483.1 1581843 R 418136 CDS YP_001122484.1 134302514 4959206 complement(1583810..1584442) 1 NC_009257.1 peptide deformylase 1584442 def1 4959206 def1 Francisella tularensis subsp. tularensis WY96-3418 peptide deformylase YP_001122484.1 1583810 R 418136 CDS YP_001122485.1 134302515 4959742 complement(1584521..1588000) 1 NC_009257.1 DNA polymerase III subunit alpha 1588000 dnaE 4959742 dnaE Francisella tularensis subsp. tularensis WY96-3418 DNA polymerase III subunit alpha YP_001122485.1 1584521 R 418136 CDS YP_001122486.1 134302516 4959818 complement(1588250..1589080) 1 NC_009257.1 hypothetical protein 1589080 4959818 FTW_1673 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122486.1 1588250 R 418136 CDS YP_001122487.1 134302517 4959879 complement(1589370..1591313) 1 NC_009257.1 lytic murein transglycosylase 1591313 4959879 FTW_1674 Francisella tularensis subsp. tularensis WY96-3418 lytic murein transglycosylase YP_001122487.1 1589370 R 418136 CDS YP_001122488.1 134302518 4958893 1591545..1592663 1 NC_009257.1 BNR/Asp-box repeat-containing protein 1592663 4958893 FTW_1675 Francisella tularensis subsp. tularensis WY96-3418 BNR/Asp-box repeat-containing protein YP_001122488.1 1591545 D 418136 CDS YP_001122489.1 134302519 4959962 1592656..1593255 1 NC_009257.1 hypothetical protein 1593255 4959962 FTW_1676 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122489.1 1592656 D 418136 CDS YP_001122490.1 134302520 4960094 complement(1593242..1593928) 1 NC_009257.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1593928 mtnN 4960094 mtnN Francisella tularensis subsp. tularensis WY96-3418 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_001122490.1 1593242 R 418136 CDS YP_001122491.1 134302521 4960138 complement(1593928..1596153) 1 NC_009257.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1596153 parC 4960138 parC Francisella tularensis subsp. tularensis WY96-3418 DNA topoisomerase IV subunit A YP_001122491.1 1593928 R 418136 CDS YP_001122492.1 134302522 4958758 complement(1596286..1596999) 1 NC_009257.1 hypothetical protein 1596999 4958758 FTW_1679 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122492.1 1596286 R 418136 CDS YP_001122493.1 134302523 4958808 complement(1597045..1597893) 1 NC_009257.1 hypothetical protein 1597893 4958808 FTW_1680 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122493.1 1597045 R 418136 CDS YP_001122494.1 134302524 4959058 complement(1597895..1598665) 1 NC_009257.1 methionine aminopeptidase 1598665 map 4959058 map Francisella tularensis subsp. tularensis WY96-3418 methionine aminopeptidase YP_001122494.1 1597895 R 418136 CDS YP_001122495.1 134302525 4958862 1598792..1599121 1 NC_009257.1 hypothetical protein 1599121 4958862 FTW_1682 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122495.1 1598792 D 418136 CDS YP_001122496.1 134302526 4959337 1599370..1599573 1 NC_009257.1 Ribonuclease B OB domain protein; cold shock protein 1599573 4959337 FTW_1683 Francisella tularensis subsp. tularensis WY96-3418 cold shock protein YP_001122496.1 1599370 D 418136 CDS YP_001122497.1 134302527 4959330 1599573..1599770 1 NC_009257.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1599770 rpsU 4959330 rpsU Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S21 YP_001122497.1 1599573 D 418136 CDS YP_001122498.1 134302528 4959359 complement(1600371..1602209) 1 NC_009257.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1602209 glmS 4959359 glmS Francisella tularensis subsp. tularensis WY96-3418 glucosamine--fructose-6-phosphate aminotransferase YP_001122498.1 1600371 R 418136 CDS YP_001122499.1 134302529 4959306 complement(1602230..1603597) 1 NC_009257.1 UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase 1603597 glmU 4959306 glmU Francisella tularensis subsp. tularensis WY96-3418 UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase YP_001122499.1 1602230 R 418136 CDS YP_001122500.1 134302530 4959200 complement(1603611..1604654) 1 NC_009257.1 NadM-Nudix subfamily; involved in creation of nicotanimide adenine dinucleotide NAD from either biosynthetic or salvage pathways; bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase 1604654 4959200 FTW_1688 Francisella tularensis subsp. tularensis WY96-3418 bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase YP_001122500.1 1603611 R 418136 CDS YP_001122501.1 134302531 4959133 complement(1604663..1605601) 1 NC_009257.1 hypothetical protein 1605601 4959133 FTW_1689 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122501.1 1604663 R 418136 CDS YP_001122502.1 134302532 4958766 1605743..1606594 1 NC_009257.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 1606594 psd 4958766 psd Francisella tularensis subsp. tularensis WY96-3418 phosphatidylserine decarboxylase YP_001122502.1 1605743 D 418136 CDS YP_001122503.1 134302533 4958919 complement(1606567..1606902) 1 NC_009257.1 hypothetical protein 1606902 4958919 FTW_1691 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122503.1 1606567 R 418136 CDS YP_001122504.1 134302534 4959149 join(1608991..1609320,1609320..1609871) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1609871 4959149 FTW_1694 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122504.1 1608991 D 418136 CDS YP_001122505.1 134302535 4959166 complement(1609899..1610348) 1 NC_009257.1 hypothetical protein 1610348 4959166 FTW_1696 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122505.1 1609899 R 418136 CDS YP_001122506.1 134302536 4959182 1610830..1611561 1 NC_009257.1 phenol 2-monooxygenase 1611561 poxF 4959182 poxF Francisella tularensis subsp. tularensis WY96-3418 phenol 2-monooxygenase YP_001122506.1 1610830 D 418136 CDS YP_001122507.2 162329652 4958729 1611683..1611898 1 NC_009257.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1611898 rpmE 4958729 rpmE Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L31 YP_001122507.2 1611683 D 418136 CDS YP_001122508.1 134302538 4958756 complement(1612110..1613615) 1 NC_009257.1 glutamate--cysteine ligase 1613615 gshA 4958756 gshA Francisella tularensis subsp. tularensis WY96-3418 glutamate--cysteine ligase YP_001122508.1 1612110 R 418136 CDS YP_001122509.1 134302539 4958887 complement(1613668..1615212) 1 NC_009257.1 conserved virulence factor; integral membrane protein MviN 1615212 mviN 4958887 mviN Francisella tularensis subsp. tularensis WY96-3418 integral membrane protein MviN YP_001122509.1 1613668 R 418136 CDS YP_001122510.1 134302540 4960175 complement(1615235..1616296) 1 NC_009257.1 hypothetical protein 1616296 4960175 FTW_1703 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122510.1 1615235 R 418136 CDS YP_001122511.1 134302541 4958848 complement(1616379..1616789) 1 NC_009257.1 ATPase; hypothetical protein 1616789 4958848 FTW_1704 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122511.1 1616379 R 418136 CDS YP_001122512.1 134302542 4959356 complement(1616767..1617948) 1 NC_009257.1 presence of both enzymatic activities needs to be experiementally confirmed, protein not always bifunctional; dihydrofolate synthetase 1617948 folC 4959356 folC Francisella tularensis subsp. tularensis WY96-3418 dihydrofolate synthetase YP_001122512.1 1616767 R 418136 CDS YP_001122513.1 134302543 4960195 complement(1617963..1618865) 1 NC_009257.1 acetyl-CoA carboxylase, carboxyl transferase subunit beta 1618865 accD 4960195 accD Francisella tularensis subsp. tularensis WY96-3418 acetyl-CoA carboxylase, carboxyl transferase subunit beta YP_001122513.1 1617963 R 418136 CDS YP_001122514.1 134302544 4958724 complement(1618907..1619329) 1 NC_009257.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1619329 ndk 4958724 ndk Francisella tularensis subsp. tularensis WY96-3418 nucleoside diphosphate kinase YP_001122514.1 1618907 R 418136 CDS YP_001122515.1 134302545 4960208 complement(1619402..1621042) 1 NC_009257.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1621042 pyrG 4960208 pyrG Francisella tularensis subsp. tularensis WY96-3418 CTP synthetase YP_001122515.1 1619402 R 418136 CDS YP_001122516.1 134302546 4960223 complement(1623099..1624055) 1 NC_009257.1 hypothetical protein 1624055 4960223 FTW_1711 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122516.1 1623099 R 418136 CDS YP_001122517.1 134302547 4960525 join(1624428..1624757,1624757..1625308) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1625308 4960525 FTW_1713 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122517.1 1624428 D 418136 CDS YP_001122518.1 134302548 4960291 1626216..1627211 1 NC_009257.1 hypothetical protein 1627211 4960291 FTW_1715 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122518.1 1626216 D 418136 CDS YP_001122519.1 134302549 4960369 complement(join(1627407..1627958,1627958..1628287)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1628287 4960369 FTW_1716 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122519.1 1627407 R 418136 CDS YP_001122520.1 134302550 4960351 1628455..1629327 1 NC_009257.1 hypothetical protein 1629327 4960351 FTW_1718 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122520.1 1628455 D 418136 CDS YP_001122521.1 134302551 4959385 1629586..1630935 1 NC_009257.1 amino acid transporter 1630935 4959385 FTW_1719 Francisella tularensis subsp. tularensis WY96-3418 amino acid transporter YP_001122521.1 1629586 D 418136 CDS YP_001122522.1 134302552 4958765 complement(1630957..1631781) 1 NC_009257.1 short chain dehydrogenase/reductase family oxidoreductase 1631781 4958765 FTW_1720 Francisella tularensis subsp. tularensis WY96-3418 short chain dehydrogenase/reductase family oxidoreductase YP_001122522.1 1630957 R 418136 CDS YP_001122523.1 134302553 4960461 complement(1631918..1632388) 1 NC_009257.1 hypothetical protein 1632388 4960461 FTW_1721 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122523.1 1631918 R 418136 CDS YP_001122524.1 134302554 4960473 complement(1632442..1633479) 1 NC_009257.1 predicted flavoproteins; hypothetical protein 1633479 4960473 FTW_1722 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122524.1 1632442 R 418136 CDS YP_001122525.1 134302555 4960495 join(1633654..1633983,1633983..1634534) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1634534 4960495 FTW_1723 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122525.1 1633654 D 418136 CDS YP_001122526.1 134302556 4959180 complement(1634730..1635725) 1 NC_009257.1 hypothetical protein 1635725 4959180 FTW_1725 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122526.1 1634730 R 418136 CDS YP_001122527.1 134302557 4959230 complement(join(1636633..1637184,1637184..1637513)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1637513 4959230 FTW_1727 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122527.1 1636633 R 418136 CDS YP_001122528.1 134302558 4959570 1637675..1639561 1 NC_009257.1 molecular chaperone; heat shock protein 90 1639561 htpG 4959570 htpG Francisella tularensis subsp. tularensis WY96-3418 heat shock protein 90 YP_001122528.1 1637675 D 418136 CDS YP_001122529.1 134302559 4959606 complement(join(1639791..1640342,1640342..1640671)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1640671 4959606 FTW_1730 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122529.1 1639791 R 418136 CDS YP_001122530.1 134302560 4959674 complement(1640825..1641262) 1 NC_009257.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1641262 rplQ 4959674 rplQ Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L17 YP_001122530.1 1640825 R 418136 CDS YP_001122531.1 134302561 4959710 complement(1641307..1642278) 1 NC_009257.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1642278 rpoA2 4959710 rpoA2 Francisella tularensis subsp. tularensis WY96-3418 DNA-directed RNA polymerase subunit alpha YP_001122531.1 1641307 R 418136 CDS YP_001122532.1 134302562 4959754 complement(1642336..1642956) 1 NC_009257.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1642956 rpsD 4959754 rpsD Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S4 YP_001122532.1 1642336 R 418136 CDS YP_001122533.1 134302563 4959762 complement(1642978..1643367) 1 NC_009257.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1643367 rpsK 4959762 rpsK Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S11 YP_001122533.1 1642978 R 418136 CDS YP_001122534.1 134302564 4959791 complement(1643407..1643763) 1 NC_009257.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1643763 rpsM 4959791 rpsM Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S13 YP_001122534.1 1643407 R 418136 CDS YP_001122535.1 134302565 4959840 complement(1643880..1643993) 1 NC_009257.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 1643993 rpmJ 4959840 rpmJ Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L36 YP_001122535.1 1643880 R 418136 CDS YP_001122536.1 134302566 4959890 complement(1644017..1645342) 1 NC_009257.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1645342 secY 4959890 secY Francisella tularensis subsp. tularensis WY96-3418 preprotein translocase subunit SecY YP_001122536.1 1644017 R 418136 CDS YP_001122537.1 134302567 4959929 complement(1645353..1645784) 1 NC_009257.1 late assembly protein; 50S ribosomal protein L15 1645784 rplO 4959929 rplO Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L15 YP_001122537.1 1645353 R 418136 CDS YP_001122538.1 134302568 4960065 complement(1645791..1645976) 1 NC_009257.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 1645976 rpmD 4960065 rpmD Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L30 YP_001122538.1 1645791 R 418136 CDS YP_001122539.1 134302569 4960089 complement(1645983..1646483) 1 NC_009257.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1646483 rpsE 4960089 rpsE Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S5 YP_001122539.1 1645983 R 418136 CDS YP_001122540.1 134302570 4960116 complement(1646511..1646864) 1 NC_009257.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1646864 rplR 4960116 rplR Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L18 YP_001122540.1 1646511 R 418136 CDS YP_001122541.1 134302571 4960135 complement(1646887..1647423) 1 NC_009257.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1647423 rplF 4960135 rplF Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L6 YP_001122541.1 1646887 R 418136 CDS YP_001122542.1 134302572 4958702 complement(1647442..1647840) 1 NC_009257.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1647840 rpsH 4958702 rpsH Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S8 YP_001122542.1 1647442 R 418136 CDS YP_001122543.1 134302573 4958867 complement(1647857..1648162) 1 NC_009257.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1648162 rpsN 4958867 rpsN Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S14 YP_001122543.1 1647857 R 418136 CDS YP_001122544.1 134302574 4958839 complement(1648181..1648720) 1 NC_009257.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1648720 rplE 4958839 rplE Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L5 YP_001122544.1 1648181 R 418136 CDS YP_001122545.1 134302575 4959362 complement(1648733..1649050) 1 NC_009257.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1649050 rplX 4959362 rplX Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L24 YP_001122545.1 1648733 R 418136 CDS YP_001122546.1 134302576 4959259 complement(1649072..1649440) 1 NC_009257.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1649440 rplN 4959259 rplN Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L14 YP_001122546.1 1649072 R 418136 CDS YP_001122547.1 134302577 4959212 complement(1649532..1649783) 1 NC_009257.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1649783 rpsQ 4959212 rpsQ Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S17 YP_001122547.1 1649532 R 418136 CDS YP_001122548.1 134302631 4959394 complement(1649796..1649996) 1 NC_009257.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 1649996 4959394 FTW_2082 Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L29 YP_001122548.1 1649796 R 418136 CDS YP_001122549.1 134302578 4959431 complement(1649996..1650409) 1 NC_009257.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1650409 rplP 4959431 rplP Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L16 YP_001122549.1 1649996 R 418136 CDS YP_001122550.1 134302579 4959210 complement(1650409..1651080) 1 NC_009257.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1651080 rpsC 4959210 rpsC Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S3 YP_001122550.1 1650409 R 418136 CDS YP_001122551.1 134302580 4959271 complement(1651095..1651430) 1 NC_009257.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1651430 rplV 4959271 rplV Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L22 YP_001122551.1 1651095 R 418136 CDS YP_001122552.1 134302581 4959209 complement(1651446..1651724) 1 NC_009257.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1651724 rpsS 4959209 rpsS Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S19 YP_001122552.1 1651446 R 418136 CDS YP_001122553.1 134302582 4959199 complement(1651739..1652563) 1 NC_009257.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1652563 rplB 4959199 rplB Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L2 YP_001122553.1 1651739 R 418136 CDS YP_001122554.1 134302583 4958865 complement(1652585..1652884) 1 NC_009257.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1652884 rplW 4958865 rplW Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L23 YP_001122554.1 1652585 R 418136 CDS YP_001122555.1 134302584 4958885 complement(1652881..1653504) 1 NC_009257.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1653504 rplD 4958885 rplD Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L4 YP_001122555.1 1652881 R 418136 CDS YP_001122556.1 134302585 4959183 complement(1653537..1654169) 1 NC_009257.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1654169 rplC 4959183 rplC Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L3 YP_001122556.1 1653537 R 418136 CDS YP_001122557.1 134302586 4958989 complement(1654273..1654590) 1 NC_009257.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 1654590 rpsJ 4958989 rpsJ Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S10 YP_001122557.1 1654273 R 418136 CDS YP_001122558.1 134302587 4959159 complement(1654611..1656725) 1 NC_009257.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1656725 fusA 4959159 fusA Francisella tularensis subsp. tularensis WY96-3418 elongation factor G YP_001122558.1 1654611 R 418136 CDS YP_001122559.1 134302588 4959176 complement(1656740..1657213) 1 NC_009257.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1657213 rpsG 4959176 rpsG Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S7 YP_001122559.1 1656740 R 418136 CDS YP_001122560.1 134302589 4959032 complement(1657252..1657626) 1 NC_009257.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1657626 rpsL 4959032 rpsL Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S12 YP_001122560.1 1657252 R 418136 CDS YP_001122561.1 134302590 4958980 complement(1657761..1658357) 1 NC_009257.1 phosphatidylglycerophosphate synthetase 1658357 pgsA 4958980 pgsA Francisella tularensis subsp. tularensis WY96-3418 phosphatidylglycerophosphate synthetase YP_001122561.1 1657761 R 418136 CDS YP_001122562.1 134302591 4958713 complement(1658361..1658807) 1 NC_009257.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 1658807 dut 4958713 dut Francisella tularensis subsp. tularensis WY96-3418 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001122562.1 1658361 R 418136 CDS YP_001122563.1 134302592 4958804 complement(1658817..1659611) 1 NC_009257.1 phosphatidate cytidylyltransferase 1659611 cdsA 4958804 cdsA Francisella tularensis subsp. tularensis WY96-3418 phosphatidate cytidylyltransferase YP_001122563.1 1658817 R 418136 CDS YP_001122564.1 134302593 4959165 complement(1659625..1660347) 1 NC_009257.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 1660347 uppS 4959165 uppS Francisella tularensis subsp. tularensis WY96-3418 undecaprenyl pyrophosphate synthase YP_001122564.1 1659625 R 418136 CDS YP_001122565.1 134302594 4960185 complement(1660431..1660988) 1 NC_009257.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1660988 frr 4960185 frr Francisella tularensis subsp. tularensis WY96-3418 ribosome recycling factor YP_001122565.1 1660431 R 418136 CDS YP_001122566.1 134302595 4960191 complement(1661017..1661766) 1 NC_009257.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1661766 pyrH 4960191 pyrH Francisella tularensis subsp. tularensis WY96-3418 uridylate kinase YP_001122566.1 1661017 R 418136 CDS YP_001122567.1 134302596 4960460 complement(1661770..1662639) 1 NC_009257.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1662639 tsf 4960460 tsf Francisella tularensis subsp. tularensis WY96-3418 elongation factor Ts YP_001122567.1 1661770 R 418136 CDS YP_001122568.1 134302597 4960218 complement(1662661..1663380) 1 NC_009257.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1663380 rpsB 4960218 rpsB Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S2 YP_001122568.1 1662661 R 418136 CDS YP_001122569.1 134302598 4960231 1663588..1664112 1 NC_009257.1 dihydrofolate reductase type I 1664112 folA 4960231 folA Francisella tularensis subsp. tularensis WY96-3418 dihydrofolate reductase type I YP_001122569.1 1663588 D 418136 CDS YP_001122570.1 134302599 4959445 complement(1667941..1668918) 1 NC_009257.1 hypothetical protein 1668918 4959445 FTW_1777 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122570.1 1667941 R 418136 CDS YP_001122571.1 134302600 4960431 complement(1668909..1670315) 1 NC_009257.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1670315 gltX 4960431 gltX Francisella tularensis subsp. tularensis WY96-3418 glutamyl-tRNA synthetase YP_001122571.1 1668909 R 418136 CDS YP_001122572.1 134302601 4960398 complement(1670445..1671836) 1 NC_009257.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1671836 fumC 4960398 fumC Francisella tularensis subsp. tularensis WY96-3418 fumarate hydratase YP_001122572.1 1670445 R 418136 CDS YP_001122573.1 134302602 4960371 complement(1672009..1672386) 1 NC_009257.1 MutT/nudix family protein 1672386 4960371 FTW_1780 Francisella tularensis subsp. tularensis WY96-3418 MutT/nudix family protein YP_001122573.1 1672009 R 418136 CDS YP_001122574.1 134302603 4960312 1672526..1673212 1 NC_009257.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 1673212 nfnB 4960312 nfnB Francisella tularensis subsp. tularensis WY96-3418 dihydropteridine reductase YP_001122574.1 1672526 D 418136 CDS YP_001122575.1 134302604 4960246 1673202..1674359 1 NC_009257.1 L-lactate dehydrogenase 1674359 lldD 4960246 lldD Francisella tularensis subsp. tularensis WY96-3418 L-lactate dehydrogenase YP_001122575.1 1673202 D 418136 CDS YP_001122576.1 134302605 4960104 complement(1674356..1674691) 1 NC_009257.1 cell envelope; hypothetical protein 1674691 4960104 FTW_1783 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122576.1 1674356 R 418136 CDS YP_001122577.1 134302606 4959986 complement(1674875..1675831) 1 NC_009257.1 hypothetical protein 1675831 4959986 FTW_1784 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122577.1 1674875 R 418136 CDS YP_001122578.1 134302607 4959948 complement(1675821..1676675) 1 NC_009257.1 hypothetical protein 1676675 4959948 FTW_1785 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122578.1 1675821 R 418136 CDS YP_001122579.1 134302608 4959917 complement(1676704..1679463) 1 NC_009257.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1679463 valS 4959917 valS Francisella tularensis subsp. tularensis WY96-3418 valyl-tRNA synthetase YP_001122579.1 1676704 R 418136 CDS YP_001122580.1 134302609 4959906 complement(1679595..1680032) 1 NC_009257.1 DNA polymerase III subunit chi 1680032 holC 4959906 holC Francisella tularensis subsp. tularensis WY96-3418 DNA polymerase III subunit chi YP_001122580.1 1679595 R 418136 CDS YP_001122581.1 134302610 4959814 complement(1680066..1680548) 1 NC_009257.1 putative cytochrome c-type biogenesis protein 1680548 4959814 FTW_1788 Francisella tularensis subsp. tularensis WY96-3418 putative cytochrome c-type biogenesis protein YP_001122581.1 1680066 R 418136 CDS YP_001122582.1 134302611 4959805 complement(1680556..1681224) 1 NC_009257.1 pyrrolidone-carboxylate peptidase 1681224 pcp 4959805 pcp Francisella tularensis subsp. tularensis WY96-3418 pyrrolidone-carboxylate peptidase YP_001122582.1 1680556 R 418136 CDS YP_001122583.1 134302612 4960503 complement(1681231..1682856) 1 NC_009257.1 hypothetical protein 1682856 4960503 FTW_1790 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122583.1 1681231 R 418136 CDS YP_001122584.1 134302613 4959645 complement(1684472..1685473) 1 NC_009257.1 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; hypothetical protein 1685473 4959645 FTW_1793 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122584.1 1684472 R 418136 CDS YP_001122585.1 134302614 4959566 complement(1685470..1685946) 1 NC_009257.1 hypothetical protein 1685946 4959566 FTW_1794 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122585.1 1685470 R 418136 CDS YP_001122586.1 134302615 4959696 complement(1685936..1686847) 1 NC_009257.1 contains a von Willebrand factor type A (vWA) domain; hypothetical protein 1686847 4959696 FTW_1795 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122586.1 1685936 R 418136 CDS YP_001122587.1 134302616 4959980 complement(1686860..1687816) 1 NC_009257.1 methanol dehydrogenase regulatory protein 1687816 moxR 4959980 moxR Francisella tularensis subsp. tularensis WY96-3418 methanol dehydrogenase regulatory protein YP_001122587.1 1686860 R 418136 CDS YP_001122588.1 134302617 4960437 1687962..1688396 1 NC_009257.1 Possibly located in cell envelope; hypothetical protein 1688396 4960437 FTW_1797 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122588.1 1687962 D 418136 CDS YP_001122589.1 134302618 4960498 1688403..1689254 1 NC_009257.1 pyridoxal kinase 1689254 pdxY 4960498 pdxY Francisella tularensis subsp. tularensis WY96-3418 pyridoxal kinase YP_001122589.1 1688403 D 418136 CDS YP_001122590.1 134302619 4959096 1689254..1689949 1 NC_009257.1 hypothetical protein 1689949 4959096 FTW_1799 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122590.1 1689254 D 418136 CDS YP_001122591.1 134302620 4959156 1690017..1691060 1 NC_009257.1 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase 1691060 lpxD2 4959156 lpxD2 Francisella tularensis subsp. tularensis WY96-3418 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase YP_001122591.1 1690017 D 418136 CDS YP_001122592.1 134302621 4959221 complement(1691209..1692057) 1 NC_009257.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 1692057 cyoE 4959221 cyoE Francisella tularensis subsp. tularensis WY96-3418 protoheme IX farnesyltransferase YP_001122592.1 1691209 R 418136 CDS YP_001122593.1 134302622 4959123 complement(1692088..1692420) 1 NC_009257.1 cytochrome o ubiquinol oxidase subunit IV 1692420 cyoD 4959123 cyoD Francisella tularensis subsp. tularensis WY96-3418 cytochrome o ubiquinol oxidase subunit IV YP_001122593.1 1692088 R 418136 CDS YP_001122594.1 134302623 4960527 complement(1692422..1693024) 1 NC_009257.1 cytochrome o ubiquinol oxidase subunit III 1693024 cyoC 4960527 cyoC Francisella tularensis subsp. tularensis WY96-3418 cytochrome o ubiquinol oxidase subunit III YP_001122594.1 1692422 R 418136 CDS YP_001122595.1 134302624 4959755 complement(1693021..1695051) 1 NC_009257.1 cytochrome o ubiquinol oxidase subunit I 1695051 cyoB 4959755 cyoB Francisella tularensis subsp. tularensis WY96-3418 cytochrome o ubiquinol oxidase subunit I YP_001122595.1 1693021 R 418136 CDS YP_001122596.1 134302625 4960509 complement(1695090..1695992) 1 NC_009257.1 cytochrome O ubiquinol oxidase, subunit II 1695992 cyoA 4960509 cyoA Francisella tularensis subsp. tularensis WY96-3418 cytochrome O ubiquinol oxidase, subunit II YP_001122596.1 1695090 R 418136 CDS YP_001122597.1 134302626 4960396 1696353..1697720 1 NC_009257.1 major facilitator superfamily transporter 1697720 4960396 FTW_1806 Francisella tularensis subsp. tularensis WY96-3418 major facilitator superfamily transporter YP_001122597.1 1696353 D 418136 CDS YP_001122598.1 134302627 4960546 1698173..1699927 1 NC_009257.1 cytochrome D ubiquinol oxidase subunit I 1699927 cydA 4960546 cydA Francisella tularensis subsp. tularensis WY96-3418 cytochrome D ubiquinol oxidase subunit I YP_001122598.1 1698173 D 418136 CDS YP_001122599.1 134302628 4959361 1699938..1701131 1 NC_009257.1 cytochrome D ubiquinol oxidase subunit II 1701131 cydB 4959361 cydB Francisella tularensis subsp. tularensis WY96-3418 cytochrome D ubiquinol oxidase subunit II YP_001122599.1 1699938 D 418136 CDS YP_001122600.1 134302629 4959152 1701324..1702064 1 NC_009257.1 cyclohexadienyl dehydratase 1702064 pheC 4959152 pheC Francisella tularensis subsp. tularensis WY96-3418 cyclohexadienyl dehydratase YP_001122600.1 1701324 D 418136 CDS YP_001122601.1 134302632 4959768 complement(join(1703229..1703780,1703780..1704109)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1704109 4959768 FTW_1812 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122601.1 1703229 R 418136 CDS YP_001122602.1 134302633 4960510 complement(1704599..1705558) 1 NC_009257.1 hypothetical protein 1705558 4960510 FTW_1814 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122602.1 1704599 R 418136 CDS YP_001122603.1 134302634 4959624 complement(1705895..1706863) 1 NC_009257.1 lipopolysaccharide core biosynthesis protein 1706863 lpsA 4959624 lpsA Francisella tularensis subsp. tularensis WY96-3418 lipopolysaccharide core biosynthesis protein YP_001122603.1 1705895 R 418136 CDS YP_001122604.1 134302635 4959653 1707052..1708908 1 NC_009257.1 ribonuclease II family protein 1708908 4959653 FTW_1816 Francisella tularensis subsp. tularensis WY96-3418 ribonuclease II family protein YP_001122604.1 1707052 D 418136 CDS YP_001122605.1 134302636 4959689 1709254..1709907 1 NC_009257.1 phospholipase/carboxylesterase family protein 1709907 4959689 FTW_1817 Francisella tularensis subsp. tularensis WY96-3418 phospholipase/carboxylesterase family protein YP_001122605.1 1709254 D 418136 CDS YP_001122606.1 134302637 4959733 1709904..1710806 1 NC_009257.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 1710806 hemC 4959733 hemC Francisella tularensis subsp. tularensis WY96-3418 porphobilinogen deaminase YP_001122606.1 1709904 D 418136 CDS YP_001122607.1 134302638 4959777 1710807..1711202 1 NC_009257.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1711202 crcB 4959777 crcB Francisella tularensis subsp. tularensis WY96-3418 camphor resistance protein CrcB YP_001122607.1 1710807 D 418136 CDS YP_001122608.1 134302639 4959794 1711253..1711606 1 NC_009257.1 hypothetical protein 1711606 4959794 FTW_1820 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122608.1 1711253 D 418136 CDS YP_001122609.1 134302640 4959927 complement(1712238..1712411) 1 NC_009257.1 hypothetical protein 1712411 4959927 FTW_1823 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122609.1 1712238 R 418136 CDS YP_001122610.1 134302641 4959846 1712541..1714340 1 NC_009257.1 Maps HMM profile PF00528: ABC transporter, permease protein; ABC transporter membrane protein 1714340 4959846 FTW_1824 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter membrane protein YP_001122610.1 1712541 D 418136 CDS YP_001122611.1 134302642 4960021 1714359..1715675 1 NC_009257.1 Maps to pfam profile PF00005: ABC transporter, ATP-binding protein; ABC transporter ATP-binding protein 1715675 4960021 FTW_1825 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter ATP-binding protein YP_001122611.1 1714359 D 418136 CDS YP_001122612.1 134302643 4960048 1715762..1717300 1 NC_009257.1 hypothetical protein 1717300 4960048 FTW_1826 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122612.1 1715762 D 418136 CDS YP_001122613.1 134302644 4960053 1717406..1719280 1 NC_009257.1 Maps to pfam profile PF00999: transporter, monovalent cation:proton antiporter-2 (CPA2) family. Also maps to COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; monovalent cation:proton antiporter-2 (CPA2) family protein 1719280 4960053 FTW_1827 Francisella tularensis subsp. tularensis WY96-3418 monovalent cation:proton antiporter-2 (CPA2) family protein YP_001122613.1 1717406 D 418136 CDS YP_001122614.1 134302645 4960081 1719265..1719804 1 NC_009257.1 acyltransferase/carbonic anhydrase family 3 protein 1719804 4960081 FTW_1828 Francisella tularensis subsp. tularensis WY96-3418 acyltransferase/carbonic anhydrase family 3 protein YP_001122614.1 1719265 D 418136 CDS YP_001122615.1 134302646 4960097 1719767..1720390 1 NC_009257.1 Maps to pfam profile PF03550: Outer membrane lipoprotein LolB; outer membrane lipoprotein LolB 1720390 lolB2 4960097 lolB2 Francisella tularensis subsp. tularensis WY96-3418 outer membrane lipoprotein LolB YP_001122615.1 1719767 D 418136 CDS YP_001122616.1 134302647 4960056 1720378..1721205 1 NC_009257.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1721205 ipk 4960056 ipk Francisella tularensis subsp. tularensis WY96-3418 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_001122616.1 1720378 D 418136 CDS YP_001122617.1 134302648 4959589 1721394..1721714 1 NC_009257.1 hypothetical protein 1721714 4959589 FTW_1831 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122617.1 1721394 D 418136 CDS YP_001122618.1 134302649 4960121 join(1721738..1722067,1722067..1722306) 1 NC_009257.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. This gene contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' which permits frameshifting to produce a single ORF; programmed frameshift; transposase ISFtu1 1722306 4960121 FTW_1832 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122618.1 1721738 D 418136 CDS YP_001122619.1 134302650 4960168 complement(1722554..1722901) 1 NC_009257.1 hypothetical protein 1722901 4960168 FTW_1835 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122619.1 1722554 R 418136 CDS YP_001122620.1 134302651 4960180 complement(1723150..1724145) 1 NC_009257.1 Maps to pfam profile PF01384: Phosphate transporter family; phosphate transporter family protein 1724145 4960180 FTW_1836 Francisella tularensis subsp. tularensis WY96-3418 phosphate transporter family protein YP_001122620.1 1723150 R 418136 CDS YP_001122621.1 134302652 4959218 complement(1724163..1724819) 1 NC_009257.1 Maps to COG1392 Phosphate transport regulator; hypothetical protein 1724819 4959218 FTW_1837 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122621.1 1724163 R 418136 CDS YP_001122622.1 134302653 4959366 1725057..1726601 1 NC_009257.1 Maps to pfam profile PF04185: Phosphoesterase family; phospholipase C 1726601 4959366 FTW_1838 Francisella tularensis subsp. tularensis WY96-3418 phospholipase C YP_001122622.1 1725057 D 418136 CDS YP_001122623.1 134302654 4959348 complement(1726608..1727420) 1 NC_009257.1 Maps to COG1984 Allophanate hydrolase subunit 2; hydrolase subunit 1727420 4959348 FTW_1839 Francisella tularensis subsp. tularensis WY96-3418 hydrolase subunit YP_001122623.1 1726608 R 418136 CDS YP_001122624.1 134302655 4959252 complement(1727347..1728123) 1 NC_009257.1 Maps to pfam profile PF03746: LamB/YcsF family; LamB/YcsF family protein 1728123 4959252 FTW_1840 Francisella tularensis subsp. tularensis WY96-3418 LamB/YcsF family protein YP_001122624.1 1727347 R 418136 CDS YP_001122625.1 134302656 4959268 complement(1728123..1728740) 1 NC_009257.1 Maps to COG2049 Allophanate hydrolase subunit 1; putative allophanate hydrolase subunit 1 1728740 4959268 FTW_1841 Francisella tularensis subsp. tularensis WY96-3418 putative allophanate hydrolase subunit 1 YP_001122625.1 1728123 R 418136 CDS YP_001122626.1 134302657 4959093 complement(join(1729820..1730371,1730371..1730700)) 1 NC_009257.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. This gene contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' which permits frameshifting to produce a single ORF; programmed frameshift; transposase ISFtu1 1730700 4959093 FTW_1844 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122626.1 1729820 R 418136 CDS YP_001122627.1 134302658 4958749 complement(1731060..1731896) 1 NC_009257.1 Maps to pfam profile PF00582: universal stress protein family; universal stress protein 1731896 uspA 4958749 uspA Francisella tularensis subsp. tularensis WY96-3418 universal stress protein YP_001122627.1 1731060 R 418136 CDS YP_001122628.1 134302659 4959140 complement(1731972..1734713) 1 NC_009257.1 DNA/RNA helicase 1734713 4959140 FTW_1847 Francisella tularensis subsp. tularensis WY96-3418 DNA/RNA helicase YP_001122628.1 1731972 R 418136 CDS YP_001122629.1 134302660 4958864 complement(1734697..1735476) 1 NC_009257.1 hypothetical protein 1735476 4958864 FTW_1848 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122629.1 1734697 R 418136 CDS YP_001122630.1 134302661 4959021 complement(1735549..1736112) 1 NC_009257.1 hypothetical protein 1736112 4959021 FTW_1849 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122630.1 1735549 R 418136 CDS YP_001122631.1 134302662 4958792 1736509..1736922 1 NC_009257.1 hypothetical protein 1736922 4958792 FTW_1850 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122631.1 1736509 D 418136 CDS YP_001122632.1 134302663 4959080 complement(1736933..1737805) 1 NC_009257.1 Maps to pfam profile PF00590: Tetrapyrrole (Corrin/Porphyrin) Methylases; tetrapyrrole (corrin/porphyrin) methylase family protein 1737805 4959080 FTW_1851 Francisella tularensis subsp. tularensis WY96-3418 tetrapyrrole (corrin/porphyrin) methylase family protein YP_001122632.1 1736933 R 418136 CDS YP_001122633.1 134302664 4958790 complement(1737798..1739153) 1 NC_009257.1 Maps to equivalog HMM TIGR01082: UDP-N-acetylmuramate--alanine ligase; UDP-N-acetylmuramate--L-alanine ligase 1739153 murC 4958790 murC Francisella tularensis subsp. tularensis WY96-3418 UDP-N-acetylmuramate--L-alanine ligase YP_001122633.1 1737798 R 418136 CDS YP_001122634.1 134302665 4958958 complement(1739220..1739993) 1 NC_009257.1 putative shikimate 5-dehydrogenase 1739993 4958958 FTW_1853 Francisella tularensis subsp. tularensis WY96-3418 putative shikimate 5-dehydrogenase YP_001122634.1 1739220 R 418136 CDS YP_001122635.1 134302666 4958960 1740120..1740578 1 NC_009257.1 hypothetical protein 1740578 4958960 FTW_1854 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122635.1 1740120 D 418136 CDS YP_001122636.1 134302667 4959460 1740670..1740804 1 NC_009257.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1740804 rpmH 4959460 rpmH Francisella tularensis subsp. tularensis WY96-3418 50S ribosomal protein L34 YP_001122636.1 1740670 D 418136 CDS YP_001122637.1 134302668 4960203 1741380..1743035 1 NC_009257.1 Maps to pfam PF02096: 60Kd inner membrane protein; hypothetical protein 1743035 4960203 FTW_1856 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122637.1 1741380 D 418136 CDS YP_001122638.1 134302669 4960209 1743042..1743941 1 NC_009257.1 Maps to pfam PF03279: Bacterial lipid A biosynthesis acyltransferase; putative lipid A biosynthesis acyltransferase 1743941 4960209 FTW_1857 Francisella tularensis subsp. tularensis WY96-3418 putative lipid A biosynthesis acyltransferase YP_001122638.1 1743042 D 418136 CDS YP_001122639.1 134302670 4960226 1744002..1744925 1 NC_009257.1 Mmaps to pfam PF03279: Bacterial lipid A biosynthesis acyltransferase; putative lipid A biosynthesis acyltransferase 1744925 4960226 FTW_1858 Francisella tularensis subsp. tularensis WY96-3418 putative lipid A biosynthesis acyltransferase YP_001122639.1 1744002 D 418136 CDS YP_001122640.1 134302671 4960267 1744938..1745345 1 NC_009257.1 type IV pili fiber building block protein 1745345 4960267 FTW_1859 Francisella tularensis subsp. tularensis WY96-3418 type IV pili fiber building block protein YP_001122640.1 1744938 D 418136 CDS YP_001122641.1 134302672 4960293 1745385..1745954 1 NC_009257.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1745954 efp 4960293 efp Francisella tularensis subsp. tularensis WY96-3418 elongation factor P YP_001122641.1 1745385 D 418136 CDS YP_001122642.1 134302673 4960307 1745957..1746493 1 NC_009257.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1746493 4960307 FTW_1861 Francisella tularensis subsp. tularensis WY96-3418 oligoribonuclease YP_001122642.1 1745957 D 418136 CDS YP_001122643.1 134302674 4960456 join(1746747..1747076,1747076..1747315) 1 NC_009257.1 ISFtu1. Transposase, member of the IS630 Tc-1 mariner family. This gene contains a programmed ribosomal frameshifting motif, 5'-AAAAAAAG-3' which permits frameshifting to produce a single ORF; programmed frameshift; transposase ISFtu1 1747315 4960456 FTW_1863 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122643.1 1746747 D 418136 CDS YP_001122644.1 134302675 4960544 1747861..1750104 1 NC_009257.1 Maps to equivalog HMM TIGR00437: ferrous iron transport protein B; ferrous iron transport protein B 1750104 feoB 4960544 feoB Francisella tularensis subsp. tularensis WY96-3418 ferrous iron transport protein B YP_001122644.1 1747861 D 418136 CDS YP_001122645.1 134302676 4960381 1750931..1753564 1 NC_009257.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 1753564 ppdK 4960381 ppdK Francisella tularensis subsp. tularensis WY96-3418 pyruvate phosphate dikinase YP_001122645.1 1750931 D 418136 CDS YP_001122646.1 134302677 4960418 1753964..1754851 1 NC_009257.1 Maps to equivalog HMM TIGR01122: branched-chain amino acid aminotransferase; branched-chain amino acid aminotransferase 1754851 ilvE 4960418 ilvE Francisella tularensis subsp. tularensis WY96-3418 branched-chain amino acid aminotransferase YP_001122646.1 1753964 D 418136 CDS YP_001122647.1 134302678 4960436 1754862..1756235 1 NC_009257.1 HMGL-like domain-containing protein 1756235 4960436 FTW_1869 Francisella tularensis subsp. tularensis WY96-3418 HMGL-like domain-containing protein YP_001122647.1 1754862 D 418136 CDS YP_001122648.1 134302679 4960374 complement(join(1756236..1756787,1756787..1757116)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1757116 4960374 FTW_1870 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122648.1 1756236 R 418136 CDS YP_001122649.1 134302681 4960047 complement(1757246..1759399) 1 NC_009257.1 primosomal protein N' 1759399 priA 4960047 priA Francisella tularensis subsp. tularensis WY96-3418 primosomal protein N' YP_001122649.1 1757246 R 418136 CDS YP_001122650.1 134302682 4960022 complement(1759396..1759971) 1 NC_009257.1 nicotinamide mononucleotide transporter pnuC protein 1759971 pnuC4 4960022 pnuC4 Francisella tularensis subsp. tularensis WY96-3418 nicotinamide mononucleotide transporter pnuC protein YP_001122650.1 1759396 R 418136 CDS YP_001122651.1 134302683 4960514 complement(1759990..1761177) 1 NC_009257.1 tRNA processing ribonuclease BN 1761177 4960514 FTW_1874 Francisella tularensis subsp. tularensis WY96-3418 tRNA processing ribonuclease BN YP_001122651.1 1759990 R 418136 CDS YP_001122652.1 134302684 4959981 1761184..1761780 1 NC_009257.1 flavodoxin domain-containing protein 1761780 4959981 FTW_1875 Francisella tularensis subsp. tularensis WY96-3418 flavodoxin domain-containing protein YP_001122652.1 1761184 D 418136 CDS YP_001122653.1 134302685 4959954 1761791..1762255 1 NC_009257.1 outer membrane lipoprotein 1762255 4959954 FTW_1876 Francisella tularensis subsp. tularensis WY96-3418 outer membrane lipoprotein YP_001122653.1 1761791 D 418136 CDS YP_001122654.1 134302686 4959811 1763672..1764589 1 NC_009257.1 periplasmic solute binding family protein 1764589 4959811 FTW_1879 Francisella tularensis subsp. tularensis WY96-3418 periplasmic solute binding family protein YP_001122654.1 1763672 D 418136 CDS YP_001122655.1 134302687 4960427 1764591..1765268 1 NC_009257.1 ABC transporter ATP-binding protein 1765268 4960427 FTW_1880 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter ATP-binding protein YP_001122655.1 1764591 D 418136 CDS YP_001122656.1 134302688 4960542 1765261..1766052 1 NC_009257.1 ABC transporter 1766052 4960542 FTW_1881 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter YP_001122656.1 1765261 D 418136 CDS YP_001122657.1 134302689 4960242 1766150..1766866 1 NC_009257.1 dienelactone hydrolase family protein 1766866 4960242 FTW_1882 Francisella tularensis subsp. tularensis WY96-3418 dienelactone hydrolase family protein YP_001122657.1 1766150 D 418136 CDS YP_001122658.1 134302690 4959130 complement(1766885..1767418) 1 NC_009257.1 hypoxanthine phosphoribosyltransferase 1767418 hpt 4959130 hpt Francisella tularensis subsp. tularensis WY96-3418 hypoxanthine phosphoribosyltransferase YP_001122658.1 1766885 R 418136 CDS YP_001122659.1 134302691 4959181 complement(1767422..1768708) 1 NC_009257.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1768708 purA 4959181 purA Francisella tularensis subsp. tularensis WY96-3418 adenylosuccinate synthetase YP_001122659.1 1767422 R 418136 CDS YP_001122660.1 134302692 4959207 1768885..1770432 1 NC_009257.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1770432 purH 4959207 purH Francisella tularensis subsp. tularensis WY96-3418 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_001122660.1 1768885 D 418136 CDS YP_001122661.1 134302693 4960539 complement(1772998..1774434) 1 NC_009257.1 hypothetical protein 1774434 4960539 FTW_1892 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122661.1 1772998 R 418136 CDS YP_001122662.1 134302694 4960517 complement(1774558..1775076) 1 NC_009257.1 outer membrane lipoprotein 1775076 4960517 FTW_1893 Francisella tularensis subsp. tularensis WY96-3418 outer membrane lipoprotein YP_001122662.1 1774558 R 418136 CDS YP_001122663.1 134302695 4960508 1775162..1776139 1 NC_009257.1 DNA polymerase III subunit delta 1776139 holA 4960508 holA Francisella tularensis subsp. tularensis WY96-3418 DNA polymerase III subunit delta YP_001122663.1 1775162 D 418136 CDS YP_001122664.1 134302696 4960548 1776259..1777296 1 NC_009257.1 glutamine synthetase 1777296 4960548 FTW_1895 Francisella tularensis subsp. tularensis WY96-3418 glutamine synthetase YP_001122664.1 1776259 D 418136 CDS YP_001122665.1 134302697 4960540 1777377..1778918 1 NC_009257.1 glutaminase/ankyrin repeat-containing protein 1778918 4960540 FTW_1896 Francisella tularensis subsp. tularensis WY96-3418 glutaminase/ankyrin repeat-containing protein YP_001122665.1 1777377 D 418136 CDS YP_001122666.1 134302698 4959363 1778927..1779799 1 NC_009257.1 CAAX amino terminal protease family protein 1779799 4959363 FTW_1897 Francisella tularensis subsp. tularensis WY96-3418 CAAX amino terminal protease family protein YP_001122666.1 1778927 D 418136 CDS YP_001122667.1 134302699 4959204 1779898..1780440 1 NC_009257.1 hypothetical protein 1780440 4959204 FTW_1898 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122667.1 1779898 D 418136 CDS YP_001122668.1 134302700 4958997 complement(1780825..1782507) 1 NC_009257.1 lysyl-tRNA synthetase 1782507 lysS 4958997 lysS Francisella tularensis subsp. tularensis WY96-3418 lysyl-tRNA synthetase YP_001122668.1 1780825 R 418136 CDS YP_001122669.1 134302701 4959484 complement(1782688..1783671) 1 NC_009257.1 peptide chain release factor 2 1783671 prfB 4959484 prfB Francisella tularensis subsp. tularensis WY96-3418 peptide chain release factor 2 YP_001122669.1 1782688 R 418136 CDS YP_001122670.1 134302702 4959145 1783944..1785584 1 NC_009257.1 DNA polymerase III subunit gamma and tau 1785584 dnaX 4959145 dnaX Francisella tularensis subsp. tularensis WY96-3418 DNA polymerase III subunit gamma and tau YP_001122670.1 1783944 D 418136 CDS YP_001122671.1 134302703 4960502 complement(1785598..1786458) 1 NC_009257.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 1786458 lpxC 4960502 lpxC Francisella tularensis subsp. tularensis WY96-3418 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_001122671.1 1785598 R 418136 CDS YP_001122672.1 134302704 4959288 complement(1786481..1787626) 1 NC_009257.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1787626 ftsZ 4959288 ftsZ Francisella tularensis subsp. tularensis WY96-3418 cell division protein FtsZ YP_001122672.1 1786481 R 418136 CDS YP_001122673.1 134302705 4958861 complement(1787670..1788932) 1 NC_009257.1 cell division protein FtsA 1788932 ftsA 4958861 ftsA Francisella tularensis subsp. tularensis WY96-3418 cell division protein FtsA YP_001122673.1 1787670 R 418136 CDS YP_001122674.1 134302706 4959034 complement(1789034..1789717) 1 NC_009257.1 cell division protein FtsQ 1789717 4959034 FTW_1905 Francisella tularensis subsp. tularensis WY96-3418 cell division protein FtsQ YP_001122674.1 1789034 R 418136 CDS YP_001122675.1 134302707 4959260 complement(1789714..1790604) 1 NC_009257.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 1790604 4959260 FTW_1906 Francisella tularensis subsp. tularensis WY96-3418 D-alanyl-alanine synthetase A YP_001122675.1 1789714 R 418136 CDS YP_001122676.1 134302708 4959071 complement(1790608..1791069) 1 NC_009257.1 cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein 1791069 4959071 FTW_1907 Francisella tularensis subsp. tularensis WY96-3418 cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein YP_001122676.1 1790608 R 418136 CDS YP_001122677.1 134302709 4959509 1791217..1792887 1 NC_009257.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1792887 rpsA 4959509 rpsA Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S1 YP_001122677.1 1791217 D 418136 CDS YP_001122678.1 134302710 4959510 1793005..1793547 1 NC_009257.1 Sua5/YciO/YrdC family protein 1793547 4959510 FTW_1909 Francisella tularensis subsp. tularensis WY96-3418 Sua5/YciO/YrdC family protein YP_001122678.1 1793005 D 418136 CDS YP_001122679.1 134302711 4959512 1793645..1794181 1 NC_009257.1 hypothetical protein 1794181 4959512 FTW_1910 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122679.1 1793645 D 418136 CDS YP_001122680.1 134302712 4959517 complement(1794578..1795456) 1 NC_009257.1 putative acyltransferase 1795456 4959517 FTW_1912 Francisella tularensis subsp. tularensis WY96-3418 putative acyltransferase YP_001122680.1 1794578 R 418136 CDS YP_001122681.1 134302713 4959539 complement(1795569..1797584) 1 NC_009257.1 putative ComEC/Rec2-like protein 1797584 4959539 FTW_1913 Francisella tularensis subsp. tularensis WY96-3418 putative ComEC/Rec2-like protein YP_001122681.1 1795569 R 418136 CDS YP_001122682.1 134302714 4959546 1797748..1799217 1 NC_009257.1 putative ribosomal protein S6 modification enzyme 1799217 4959546 FTW_1914 Francisella tularensis subsp. tularensis WY96-3418 putative ribosomal protein S6 modification enzyme YP_001122682.1 1797748 D 418136 CDS YP_001122683.1 134302715 4959547 1799204..1799629 1 NC_009257.1 acetyltransferase GNAT family protein 1799629 4959547 FTW_1915 Francisella tularensis subsp. tularensis WY96-3418 acetyltransferase GNAT family protein YP_001122683.1 1799204 D 418136 CDS YP_001122684.1 134302716 4959551 1800058..1801782 1 NC_009257.1 ABC transporter permease family protein 1801782 4959551 FTW_1916 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter permease family protein YP_001122684.1 1800058 D 418136 CDS YP_001122685.1 134302717 4959552 1801811..1802593 1 NC_009257.1 ABC transporter ATP-binding protein 1802593 4959552 FTW_1917 Francisella tularensis subsp. tularensis WY96-3418 ABC transporter ATP-binding protein YP_001122685.1 1801811 D 418136 CDS YP_001122686.1 134302718 4959555 complement(1802587..1803156) 1 NC_009257.1 YggT family membrane protein 1803156 4959555 FTW_1918 Francisella tularensis subsp. tularensis WY96-3418 YggT family membrane protein YP_001122686.1 1802587 R 418136 CDS YP_001122687.1 134302719 4959732 complement(join(1804509..1805060,1805060..1805389)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1805389 4959732 FTW_1920 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122687.1 1804509 R 418136 CDS YP_001122688.1 134302720 4959868 complement(1805413..1805964) 1 NC_009257.1 hypothetical protein 1805964 4959868 FTW_1922 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122688.1 1805413 R 418136 CDS YP_001122689.1 134302721 4959891 complement(1806037..1806165) 1 NC_009257.1 hypothetical protein 1806165 4959891 FTW_1923 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122689.1 1806037 R 418136 CDS YP_001122690.1 134302722 4959902 complement(1806235..1806900) 1 NC_009257.1 nitroreductase family protein 1806900 4959902 FTW_1924 Francisella tularensis subsp. tularensis WY96-3418 nitroreductase family protein YP_001122690.1 1806235 R 418136 CDS YP_001122691.1 134302723 4959920 1807125..1807244 1 NC_009257.1 hypothetical protein 1807244 4959920 FTW_1925 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122691.1 1807125 D 418136 CDS YP_001122692.1 134302724 4959928 1807303..1807995 1 NC_009257.1 hypothetical protein 1807995 4959928 FTW_1926 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122692.1 1807303 D 418136 CDS YP_001122693.1 134302725 4960496 complement(1807992..1809197) 1 NC_009257.1 aromatic amino acid transporter family protein 1809197 4960496 FTW_1927 Francisella tularensis subsp. tularensis WY96-3418 aromatic amino acid transporter family protein YP_001122693.1 1807992 R 418136 CDS YP_001122694.1 134302726 4960000 1809297..1809914 1 NC_009257.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1809914 gidB 4960000 gidB Francisella tularensis subsp. tularensis WY96-3418 16S rRNA methyltransferase GidB YP_001122694.1 1809297 D 418136 CDS YP_001122695.1 134302727 4960001 1809911..1810579 1 NC_009257.1 hypothetical protein 1810579 4960001 FTW_1929 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122695.1 1809911 D 418136 CDS YP_001122696.1 134302728 4960006 complement(1810572..1811456) 1 NC_009257.1 hypothetical protein 1811456 4960006 FTW_1930 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122696.1 1810572 R 418136 CDS YP_001122697.1 134302729 4960062 complement(1811658..1812554) 1 NC_009257.1 LysR family transcriptional regulator 1812554 4960062 FTW_1931 Francisella tularensis subsp. tularensis WY96-3418 LysR family transcriptional regulator YP_001122697.1 1811658 R 418136 CDS YP_001122698.1 134302730 4960064 1812657..1813808 1 NC_009257.1 major facilitator transporter 1813808 4960064 FTW_1932 Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001122698.1 1812657 D 418136 CDS YP_001122699.1 134302731 4960098 1816356..1816952 1 NC_009257.1 phosphoheptose isomerase 1816952 gmhA 4960098 gmhA Francisella tularensis subsp. tularensis WY96-3418 phosphoheptose isomerase YP_001122699.1 1816356 D 418136 CDS YP_001122700.1 134302732 4960142 1816960..1817316 1 NC_009257.1 outer membrane lipoprotein 1817316 4960142 FTW_1937 Francisella tularensis subsp. tularensis WY96-3418 outer membrane lipoprotein YP_001122700.1 1816960 D 418136 CDS YP_001122701.1 134302733 4960154 complement(1817390..1817662) 1 NC_009257.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1817662 rpsT 4960154 rpsT Francisella tularensis subsp. tularensis WY96-3418 30S ribosomal protein S20 YP_001122701.1 1817390 R 418136 CDS YP_001122702.1 134302734 4960156 1817932..1819716 1 NC_009257.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1819716 lepA 4960156 lepA Francisella tularensis subsp. tularensis WY96-3418 GTP-binding protein LepA YP_001122702.1 1817932 D 418136 CDS YP_001122703.1 134302735 4960160 1819730..1820809 1 NC_009257.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1820809 mnmA 4960160 mnmA Francisella tularensis subsp. tularensis WY96-3418 tRNA-specific 2-thiouridylase MnmA YP_001122703.1 1819730 D 418136 CDS YP_001122704.1 134302736 4960184 complement(1820829..1821773) 1 NC_009257.1 hypothetical protein 1821773 4960184 FTW_1941 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122704.1 1820829 R 418136 CDS YP_001122705.1 134302737 4958682 complement(1821855..1822379) 1 NC_009257.1 peptide deformylase 1822379 def2 4958682 def2 Francisella tularensis subsp. tularensis WY96-3418 peptide deformylase YP_001122705.1 1821855 R 418136 CDS YP_001122706.1 134302738 4958752 complement(1822376..1822819) 1 NC_009257.1 6,7-dimethyl-8-ribityllumazine synthase 1822819 ribH 4958752 ribH Francisella tularensis subsp. tularensis WY96-3418 6,7-dimethyl-8-ribityllumazine synthase YP_001122706.1 1822376 R 418136 CDS YP_001122707.1 134302739 4959481 complement(1822829..1824040) 1 NC_009257.1 3,4-dihydroxy-2-butanone 4-phosphate synthase 1824040 ribAB 4959481 ribAB Francisella tularensis subsp. tularensis WY96-3418 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001122707.1 1822829 R 418136 CDS YP_001122708.1 134302740 4959483 complement(1824033..1824638) 1 NC_009257.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1824638 ribE 4959483 ribE Francisella tularensis subsp. tularensis WY96-3418 riboflavin synthase subunit alpha YP_001122708.1 1824033 R 418136 CDS YP_001122709.1 134302741 4959493 complement(1824631..1825698) 1 NC_009257.1 riboflavin biosynthesis protein RibD 1825698 ribD 4959493 ribD Francisella tularensis subsp. tularensis WY96-3418 riboflavin biosynthesis protein RibD YP_001122709.1 1824631 R 418136 CDS YP_001122710.1 134302742 4959488 complement(join(1826681..1827232,1827232..1827561)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1827561 4959488 FTW_1948 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122710.1 1826681 R 418136 CDS YP_001122711.1 134302743 4959368 complement(1827825..1827995) 1 NC_009257.1 hypothetical protein 1827995 4959368 FTW_1950 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122711.1 1827825 R 418136 CDS YP_001122712.1 134302744 4959513 complement(1828546..1829769) 1 NC_009257.1 amino acid transporter 1829769 4959513 FTW_1951 Francisella tularensis subsp. tularensis WY96-3418 amino acid transporter YP_001122712.1 1828546 R 418136 CDS YP_001122713.1 134302745 4959261 complement(1830096..1830332) 1 NC_009257.1 hypothetical protein 1830332 4959261 FTW_1952 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122713.1 1830096 R 418136 CDS YP_001122714.1 134302746 4959280 1830820..1831707 1 NC_009257.1 dehydrogenase 1831707 4959280 FTW_1953 Francisella tularensis subsp. tularensis WY96-3418 dehydrogenase YP_001122714.1 1830820 D 418136 CDS YP_001122715.1 134302747 4959272 complement(1831721..1832641) 1 NC_009257.1 aspartate carbamoyltransferase 1832641 pyrB 4959272 pyrB Francisella tularensis subsp. tularensis WY96-3418 aspartate carbamoyltransferase YP_001122715.1 1831721 R 418136 CDS YP_001122716.1 134302748 4959097 complement(1832783..1836067) 1 NC_009257.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1836067 carB 4959097 carB Francisella tularensis subsp. tularensis WY96-3418 carbamoyl phosphate synthase large subunit YP_001122716.1 1832783 R 418136 CDS YP_001122717.1 134302749 4958883 complement(1836072..1837238) 1 NC_009257.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1837238 carA 4958883 carA Francisella tularensis subsp. tularensis WY96-3418 carbamoyl phosphate synthase small subunit YP_001122717.1 1836072 R 418136 CDS YP_001122718.1 134302750 4958947 complement(1838877..1839413) 1 NC_009257.1 thiopurine S-methyltransferase 1839413 4958947 FTW_1959 Francisella tularensis subsp. tularensis WY96-3418 thiopurine S-methyltransferase YP_001122718.1 1838877 R 418136 CDS YP_001122719.1 134302751 4958775 1839545..1840891 1 NC_009257.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 1840891 4958775 FTW_1960 Francisella tularensis subsp. tularensis WY96-3418 dihydroorotase YP_001122719.1 1839545 D 418136 CDS YP_001122720.1 134302752 4958956 complement(1840919..1841851) 1 NC_009257.1 hypothetical protein 1841851 4958956 FTW_1961 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122720.1 1840919 R 418136 CDS YP_001122721.1 134302753 4958782 1842197..1842451 1 NC_009257.1 hypothetical protein 1842451 4958782 FTW_1962 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122721.1 1842197 D 418136 CDS YP_001122722.1 134302754 4958924 1842498..1842701 1 NC_009257.1 hypothetical protein 1842701 4958924 FTW_1963 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122722.1 1842498 D 418136 CDS YP_001122723.1 134302755 4959467 1843165..1843716 1 NC_009257.1 hypothetical protein 1843716 4959467 FTW_1964 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122723.1 1843165 D 418136 CDS YP_001122724.1 134302756 4959470 complement(1843832..1844884) 1 NC_009257.1 hypothetical protein 1844884 4959470 FTW_1965 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122724.1 1843832 R 418136 CDS YP_001122725.1 134302757 4960204 complement(1844871..1845836) 1 NC_009257.1 HlyD family secretion protein 1845836 4960204 FTW_1966 Francisella tularensis subsp. tularensis WY96-3418 HlyD family secretion protein YP_001122725.1 1844871 R 418136 CDS YP_001122726.1 134302758 4960207 complement(1845925..1846332) 1 NC_009257.1 hypothetical protein 1846332 4960207 FTW_1967 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122726.1 1845925 R 418136 CDS YP_001122727.1 134302759 4960217 1846458..1847327 1 NC_009257.1 LysR family transcriptional regulator 1847327 4960217 FTW_1968 Francisella tularensis subsp. tularensis WY96-3418 LysR family transcriptional regulator YP_001122727.1 1846458 D 418136 CDS YP_001122728.1 134302760 4960250 complement(1847328..1847954) 1 NC_009257.1 putative SOUL heme-binding protein 1847954 4960250 FTW_1969 Francisella tularensis subsp. tularensis WY96-3418 putative SOUL heme-binding protein YP_001122728.1 1847328 R 418136 CDS YP_001122729.1 134302761 4960258 1848097..1848645 1 NC_009257.1 chorismate mutase 1848645 4960258 FTW_1970 Francisella tularensis subsp. tularensis WY96-3418 chorismate mutase YP_001122729.1 1848097 D 418136 CDS YP_001122730.1 134302762 4960537 1852361..1852984 1 NC_009257.1 orotidine 5'-phosphate decarboxylase 1852984 pyrF 4960537 pyrF Francisella tularensis subsp. tularensis WY96-3418 orotidine 5'-phosphate decarboxylase YP_001122730.1 1852361 D 418136 CDS YP_001122731.1 134302763 4960361 1852974..1853732 1 NC_009257.1 putative diyroorotate dehydrogenase 1853732 4960361 FTW_1974 Francisella tularensis subsp. tularensis WY96-3418 putative diyroorotate dehydrogenase YP_001122731.1 1852974 D 418136 CDS YP_001122732.1 134302764 4960545 complement(1854014..1854451) 1 NC_009257.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1854451 dtd 4960545 dtd Francisella tularensis subsp. tularensis WY96-3418 D-tyrosyl-tRNA(Tyr) deacylase YP_001122732.1 1854014 R 418136 CDS YP_001122733.1 134302765 4960367 complement(1854695..1855927) 1 NC_009257.1 major facilitator transporter 1855927 4960367 FTW_1976 Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001122733.1 1854695 R 418136 CDS YP_001122734.1 134302766 4960423 complement(1855946..1857658) 1 NC_009257.1 glycosyl hydrolase family protein 1857658 4960423 FTW_1977 Francisella tularensis subsp. tularensis WY96-3418 glycosyl hydrolase family protein YP_001122734.1 1855946 R 418136 CDS YP_001122735.1 134302767 4960439 complement(join(1857630..1857869,1857869..1858198)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1858198 4960439 FTW_1978 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122735.1 1857630 R 418136 CDS YP_001122736.1 134302768 4960440 complement(1858366..1858746) 1 NC_009257.1 hypothetical protein 1858746 4960440 FTW_1980 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122736.1 1858366 R 418136 CDS YP_001122737.1 134302769 4960292 1858769..1858927 1 NC_009257.1 hypothetical protein 1858927 4960292 FTW_1981 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122737.1 1858769 D 418136 CDS YP_001122738.1 134302770 4960504 complement(1858937..1860634) 1 NC_009257.1 thiamine pyrophosphate binding domain-containing protein 1860634 4960504 FTW_1982 Francisella tularensis subsp. tularensis WY96-3418 thiamine pyrophosphate binding domain-containing protein YP_001122738.1 1858937 R 418136 CDS YP_001122739.1 134302771 4959931 1861165..1862088 1 NC_009257.1 signal peptidase 1862088 4959931 FTW_1984 Francisella tularensis subsp. tularensis WY96-3418 signal peptidase YP_001122739.1 1861165 D 418136 CDS YP_001122740.1 134302772 4960501 1862142..1862717 1 NC_009257.1 OmpH-like outer membrane protein 1862717 4960501 FTW_1985 Francisella tularensis subsp. tularensis WY96-3418 OmpH-like outer membrane protein YP_001122740.1 1862142 D 418136 CDS YP_001122741.1 134302773 4959637 1862853..1863275 1 NC_009257.1 rhodanese-like domain-containing protein 1863275 4959637 FTW_1986 Francisella tularensis subsp. tularensis WY96-3418 rhodanese-like domain-containing protein YP_001122741.1 1862853 D 418136 CDS YP_001122742.1 134302774 4960488 1863302..1863751 1 NC_009257.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 1863751 secB2 4960488 secB2 Francisella tularensis subsp. tularensis WY96-3418 preprotein translocase subunit SecB YP_001122742.1 1863302 D 418136 CDS YP_001122743.1 134302775 4960485 1863773..1864852 1 NC_009257.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1864852 recA 4960485 recA Francisella tularensis subsp. tularensis WY96-3418 recombinase A YP_001122743.1 1863773 D 418136 CDS YP_001122744.1 134302776 4960492 1864839..1865291 1 NC_009257.1 regulatory protein RecX 1865291 recX 4960492 recX Francisella tularensis subsp. tularensis WY96-3418 regulatory protein RecX YP_001122744.1 1864839 D 418136 CDS YP_001122745.1 134302777 4960491 1865465..1865941 1 NC_009257.1 single-strand binding protein 1865941 ssb 4960491 ssb Francisella tularensis subsp. tularensis WY96-3418 single-strand binding protein YP_001122745.1 1865465 D 418136 CDS YP_001122746.1 134302778 4960478 1866047..1867201 1 NC_009257.1 acetate kinase 1867201 ackA 4960478 ackA Francisella tularensis subsp. tularensis WY96-3418 acetate kinase YP_001122746.1 1866047 D 418136 CDS YP_001122747.1 134302779 4960482 1867211..1869307 1 NC_009257.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 1869307 pta 4960482 pta Francisella tularensis subsp. tularensis WY96-3418 phosphate acetyltransferase YP_001122747.1 1867211 D 418136 CDS YP_001122748.1 134302780 4960487 complement(join(1870219..1870770,1870770..1871099)) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1871099 4960487 FTW_1994 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122748.1 1870219 R 418136 CDS YP_001122749.1 134302781 4960524 complement(1871595..1873367) 1 NC_009257.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1873367 aspS 4960524 aspS Francisella tularensis subsp. tularensis WY96-3418 aspartyl-tRNA synthetase YP_001122749.1 1871595 R 418136 CDS YP_001122750.1 134302782 4960115 join(1875394..1875723,1875723..1875962) 1 NC_009257.1 programmed frameshift; transposase ISFtu1 1875962 4960115 FTW_2002 Francisella tularensis subsp. tularensis WY96-3418 transposase ISFtu1 YP_001122750.1 1875394 D 418136 CDS YP_001122751.1 134302783 4960489 complement(1876049..1876843) 1 NC_009257.1 hypothetical protein 1876843 4960489 FTW_2004 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122751.1 1876049 R 418136 CDS YP_001122752.1 134302784 4960105 complement(1876800..1878479) 1 NC_009257.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 1878479 4960105 FTW_2005 Francisella tularensis subsp. tularensis WY96-3418 putative ABC transporter ATP-binding protein YP_001122752.1 1876800 R 418136 CDS YP_001122753.1 134302785 4959457 1878691..1879923 1 NC_009257.1 major facilitator transporter 1879923 4959457 FTW_2006 Francisella tularensis subsp. tularensis WY96-3418 major facilitator transporter YP_001122753.1 1878691 D 418136 CDS YP_001122754.1 134302786 4959283 complement(1880224..1880436) 1 NC_009257.1 hypothetical protein 1880436 4959283 FTW_2007 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122754.1 1880224 R 418136 CDS YP_001122755.1 134302787 4960402 1880482..1881462 1 NC_009257.1 hypothetical protein 1881462 4960402 FTW_2008 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122755.1 1880482 D 418136 CDS YP_001122756.1 134302788 4960355 complement(1881469..1882080) 1 NC_009257.1 LysE family translocator protein 1882080 4960355 FTW_2009 Francisella tularensis subsp. tularensis WY96-3418 LysE family translocator protein YP_001122756.1 1881469 R 418136 CDS YP_001122757.1 134302789 4959865 1882186..1883106 1 NC_009257.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 1883106 4959865 FTW_2010 Francisella tularensis subsp. tularensis WY96-3418 chromosome replication initiation inhibitor protein YP_001122757.1 1882186 D 418136 CDS YP_001122758.1 134302790 4960393 1883382..1884176 1 NC_009257.1 hypothetical protein 1884176 4960393 FTW_2011 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122758.1 1883382 D 418136 CDS YP_001122759.1 134302791 4960141 complement(1884336..1884479) 1 NC_009257.1 hypothetical protein 1884479 4960141 FTW_2012 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122759.1 1884336 R 418136 CDS YP_001122760.1 134302792 4959753 1888248..1888682 1 NC_009257.1 HSP20 family protein 1888682 4959753 FTW_2016 Francisella tularensis subsp. tularensis WY96-3418 HSP20 family protein YP_001122760.1 1888248 D 418136 CDS YP_001122761.1 134302793 4959126 complement(1888679..1890040) 1 NC_009257.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1890040 trpCF 4959126 trpCF Francisella tularensis subsp. tularensis WY96-3418 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_001122761.1 1888679 R 418136 CDS YP_001122762.1 134302794 4960547 complement(1890132..1890545) 1 NC_009257.1 hypothetical protein 1890545 4960547 FTW_2018 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122762.1 1890132 R 418136 CDS YP_001122763.1 134302795 4960543 complement(1890550..1891239) 1 NC_009257.1 methionine-S-sulfoxide reductase 1891239 msrA 4960543 msrA Francisella tularensis subsp. tularensis WY96-3418 methionine-S-sulfoxide reductase YP_001122763.1 1890550 R 418136 CDS YP_001122764.1 134302796 4960541 complement(1891323..1891691) 1 NC_009257.1 hypothetical protein 1891691 4960541 FTW_2020 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122764.1 1891323 R 418136 CDS YP_001122765.1 134302797 4960282 complement(1891684..1892025) 1 NC_009257.1 hypothetical protein 1892025 4960282 FTW_2021 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122765.1 1891684 R 418136 CDS YP_001122766.1 134302798 4959738 complement(1892094..1892495) 1 NC_009257.1 hypothetical protein 1892495 4959738 FTW_2022 Francisella tularensis subsp. tularensis WY96-3418 hypothetical protein YP_001122766.1 1892094 R 418136 CDS YP_001122767.1 134302799 4959048 complement(1892638..1893663) 1 NC_009257.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1893663 trpD 4959048 trpD Francisella tularensis subsp. tularensis WY96-3418 anthranilate phosphoribosyltransferase YP_001122767.1 1892638 R 418136 CDS YP_001122768.1 134302800 4959124 complement(1893648..1894226) 1 NC_009257.1 glutamine amidotransferase of anthranilate synthase 1894226 trpG 4959124 trpG Francisella tularensis subsp. tularensis WY96-3418 glutamine amidotransferase of anthranilate synthase YP_001122768.1 1893648 R 418136 CDS YP_001122769.1 134302801 4959036 complement(1894230..1895774) 1 NC_009257.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1895774 trpE 4959036 trpE Francisella tularensis subsp. tularensis WY96-3418 anthranilate synthase component I YP_001122769.1 1894230 R 418136 CDS YP_001122770.1 134302802 4959108 complement(1895783..1896070) 1 NC_009257.1 trp operon repressor 1896070 trpR 4959108 trpR Francisella tularensis subsp. tularensis WY96-3418 trp operon repressor YP_001122770.1 1895783 R 418136 CDS YP_001122771.1 134302803 4959725 complement(1896544..1898040) 1 NC_009257.1 ribonuclease 1898040 4959725 FTW_2027 Francisella tularensis subsp. tularensis WY96-3418 ribonuclease YP_001122771.1 1896544 R 418136 CDS