-- dump date 20140619_095424 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 441952000001 SEQ_END SEQ_END NC_010677.1 1893886 1893886 DR NC_010677.1; contig end 1893886..1893886 Francisella tularensis subsp. mediasiatica FSC147 YP_001890898.1 CDS dnaA NC_010677.1 130 1521 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 130..1521 Francisella tularensis subsp. mediasiatica FSC147 6291181 YP_001890899.1 CDS dnaN NC_010677.1 1558 2661 D DNA polymerase III subunit beta 1558..2661 Francisella tularensis subsp. mediasiatica FSC147 6291114 YP_001890900.1 CDS sdaC NC_010677.1 4828 6051 R serine permease complement(4828..6051) Francisella tularensis subsp. mediasiatica FSC147 6291081 YP_001890901.1 CDS FTM_0005 NC_010677.1 6379 6615 R hypothetical protein complement(6379..6615) Francisella tularensis subsp. mediasiatica FSC147 6290098 YP_001890902.1 CDS FTM_0006 NC_010677.1 7112 7990 D 3-hydroxyisobutyrate dehydrogenase 7112..7990 Francisella tularensis subsp. mediasiatica FSC147 6290376 YP_001890903.1 CDS pyrB NC_010677.1 8004 8924 R aspartate carbamoyltransferase complement(8004..8924) Francisella tularensis subsp. mediasiatica FSC147 6290658 YP_001890904.1 CDS carB NC_010677.1 9066 12350 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(9066..12350) Francisella tularensis subsp. mediasiatica FSC147 6290661 YP_001890905.1 CDS carA NC_010677.1 12355 13521 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(12355..13521) Francisella tularensis subsp. mediasiatica FSC147 6290666 YP_001890906.1 CDS FTM_0010 NC_010677.1 13937 14992 D histidine acid phosphatase 13937..14992 Francisella tularensis subsp. mediasiatica FSC147 6290674 YP_001890907.1 CDS tmpT NC_010677.1 15116 15796 R catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide; thiopurine S-methyltransferase complement(15116..15796) Francisella tularensis subsp. mediasiatica FSC147 6290679 YP_001890908.1 CDS pyrC NC_010677.1 15928 17274 D Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 15928..17274 Francisella tularensis subsp. mediasiatica FSC147 6290785 YP_001890909.1 CDS FTM_0013 NC_010677.1 17302 18321 R regulatory protein ArsR complement(17302..18321) Francisella tularensis subsp. mediasiatica FSC147 6290787 YP_001890910.1 CDS FTM_0014 NC_010677.1 18592 18834 D hypothetical protein 18592..18834 Francisella tularensis subsp. mediasiatica FSC147 6290791 YP_001890911.1 CDS FTM_0015 NC_010677.1 18881 19159 D hypothetical protein 18881..19159 Francisella tularensis subsp. mediasiatica FSC147 6290795 YP_001890912.1 CDS FTM_0017 NC_010677.1 20215 21267 R membrane protein complement(20215..21267) Francisella tularensis subsp. mediasiatica FSC147 6291440 YP_001890913.1 CDS FTM_0018 NC_010677.1 21254 22219 R HlyD family secretion protein complement(21254..22219) Francisella tularensis subsp. mediasiatica FSC147 6290388 YP_001890914.1 CDS FTM_0019 NC_010677.1 22308 22715 R membrane protein complement(22308..22715) Francisella tularensis subsp. mediasiatica FSC147 6291587 YP_001890915.1 CDS FTM_0020 NC_010677.1 22841 23710 D transcriptional regulator, LysR family 22841..23710 Francisella tularensis subsp. mediasiatica FSC147 6291242 YP_001890916.1 CDS FTM_0021 NC_010677.1 23711 24337 R soul domain-containing protein complement(23711..24337) Francisella tularensis subsp. mediasiatica FSC147 6291318 YP_001890917.1 CDS FTM_0022 NC_010677.1 24480 25028 D chorismate mutase 24480..25028 Francisella tularensis subsp. mediasiatica FSC147 6290060 YP_001890918.1 CDS pyrF NC_010677.1 28727 29371 D orotidine-5'-phosphate decarboxylase 28727..29371 Francisella tularensis subsp. mediasiatica FSC147 6290102 YP_001890919.1 CDS pyrD NC_010677.1 29373 30119 D diyroorotate dehydrogenase 29373..30119 Francisella tularensis subsp. mediasiatica FSC147 6291220 YP_001890920.1 CDS dtd NC_010677.1 30381 30860 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(30381..30860) Francisella tularensis subsp. mediasiatica FSC147 6290110 YP_001890921.1 CDS FTM_0028 NC_010677.1 32312 33790 R beta-fructofuranosidase complement(32312..33790) Francisella tularensis subsp. mediasiatica FSC147 6291395 YP_001890922.1 CDS FTM_0030 NC_010677.1 35592 36257 R nitroreductase complement(35592..36257) Francisella tularensis subsp. mediasiatica FSC147 6291199 YP_001890923.1 CDS FTM_0031 NC_010677.1 36660 37352 D hypothetical protein 36660..37352 Francisella tularensis subsp. mediasiatica FSC147 6290976 YP_001890924.1 CDS FTM_0032 NC_010677.1 37349 38554 R hydroxy/aromatic amino acid permease complement(37349..38554) Francisella tularensis subsp. mediasiatica FSC147 6290903 YP_001890925.1 CDS gidB NC_010677.1 38663 39271 D glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 38663..39271 Francisella tularensis subsp. mediasiatica FSC147 6290717 YP_001890926.1 CDS FTM_0034 NC_010677.1 39268 39936 D hypothetical protein 39268..39936 Francisella tularensis subsp. mediasiatica FSC147 6290882 YP_001890927.1 CDS FTM_0035 NC_010677.1 39929 40813 R membrane protein complement(39929..40813) Francisella tularensis subsp. mediasiatica FSC147 6290858 YP_001890928.1 CDS FTM_0036 NC_010677.1 41015 41911 R transcription regulator, LysR family complement(41015..41911) Francisella tularensis subsp. mediasiatica FSC147 6290021 YP_001890929.1 CDS FTM_0037 NC_010677.1 42014 43150 D drug:H+ antiporter-1 (DHA1) family protein 42014..43150 Francisella tularensis subsp. mediasiatica FSC147 6290245 YP_001890930.1 CDS FTM_0039 NC_010677.1 45699 46295 D phosphoheptose isomerase 45699..46295 Francisella tularensis subsp. mediasiatica FSC147 6290563 YP_001890931.1 CDS FTM_0040 NC_010677.1 46303 46659 D outer membrane lipoprotein 46303..46659 Francisella tularensis subsp. mediasiatica FSC147 6291553 YP_001890932.1 CDS rpsT NC_010677.1 46733 47005 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(46733..47005) Francisella tularensis subsp. mediasiatica FSC147 6290507 YP_001890933.1 CDS lepA NC_010677.1 47275 49068 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 47275..49068 Francisella tularensis subsp. mediasiatica FSC147 6290886 YP_001890934.1 CDS mnmA NC_010677.1 49074 50153 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 49074..50153 Francisella tularensis subsp. mediasiatica FSC147 6290706 YP_001890935.1 CDS FTM_0044 NC_010677.1 50173 51150 R lipoprotein complement(50173..51150) Francisella tularensis subsp. mediasiatica FSC147 6290001 YP_001890936.1 CDS FTM_0045 NC_010677.1 51244 51762 R peptide deformylase complement(51244..51762) Francisella tularensis subsp. mediasiatica FSC147 6290350 YP_001890937.1 CDS ribH NC_010677.1 51765 52208 R 6,7-dimethyl-8-ribityllumazine synthase complement(51765..52208) Francisella tularensis subsp. mediasiatica FSC147 6291289 YP_001890938.1 CDS FTM_0047 NC_010677.1 52218 53429 R riboflavin biosynthesis protein ribAB complement(52218..53429) Francisella tularensis subsp. mediasiatica FSC147 6291550 YP_001890939.1 CDS ribC NC_010677.1 53422 54027 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(53422..54027) Francisella tularensis subsp. mediasiatica FSC147 6290652 YP_001890940.1 CDS ribD NC_010677.1 54020 55087 R riboflavin biosynthesis protein RibD complement(54020..55087) Francisella tularensis subsp. mediasiatica FSC147 6291110 YP_001890941.1 CDS FTM_0052 NC_010677.1 57620 58012 D membrane protein 57620..58012 Francisella tularensis subsp. mediasiatica FSC147 6290088 YP_001890942.1 CDS FTM_0053 NC_010677.1 58033 58443 D membrane protein 58033..58443 Francisella tularensis subsp. mediasiatica FSC147 6291350 YP_001890943.1 CDS eriC NC_010677.1 58937 60349 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 58937..60349 Francisella tularensis subsp. mediasiatica FSC147 6290296 YP_001890944.1 CDS trpB NC_010677.1 61853 63043 D catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 61853..63043 Francisella tularensis subsp. mediasiatica FSC147 6290673 YP_001890945.1 CDS trpA NC_010677.1 63043 63852 D catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 63043..63852 Francisella tularensis subsp. mediasiatica FSC147 6290699 YP_001890946.1 CDS clpB NC_010677.1 65278 67857 D chaperone ClpB 65278..67857 Francisella tularensis subsp. mediasiatica FSC147 6290362 YP_001890947.1 CDS chiB NC_010677.1 68108 70300 D chitinase 68108..70300 Francisella tularensis subsp. mediasiatica FSC147 6291290 YP_001890948.1 CDS purT NC_010677.1 70354 71514 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 70354..71514 Francisella tularensis subsp. mediasiatica FSC147 6290165 YP_001890949.1 CDS FTM_0065 NC_010677.1 72203 72844 R membrane protein complement(72203..72844) Francisella tularensis subsp. mediasiatica FSC147 6290259 YP_001890950.1 CDS FTM_0066 NC_010677.1 73081 73404 D ferredoxin-1 73081..73404 Francisella tularensis subsp. mediasiatica FSC147 6290654 YP_001890951.1 CDS FTM_0067 NC_010677.1 73567 74319 D acyltransferase 73567..74319 Francisella tularensis subsp. mediasiatica FSC147 6290465 YP_001890952.1 CDS FTM_0068 NC_010677.1 74333 75073 D acyltransferase 74333..75073 Francisella tularensis subsp. mediasiatica FSC147 6291261 YP_001890953.1 CDS FTM_0069 NC_010677.1 75079 75798 R hypothetical protein complement(75079..75798) Francisella tularensis subsp. mediasiatica FSC147 6290641 YP_001890954.1 CDS nhaA NC_010677.1 75863 77014 R exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter complement(75863..77014) Francisella tularensis subsp. mediasiatica FSC147 6290040 YP_001890955.1 CDS FTM_0071 NC_010677.1 77108 78004 D rieske protein 77108..78004 Francisella tularensis subsp. mediasiatica FSC147 6290544 YP_001890956.1 CDS FTM_0072 NC_010677.1 78070 78579 D B-type cytochrome 78070..78579 Francisella tularensis subsp. mediasiatica FSC147 6290638 YP_001890957.1 CDS FTM_0076 NC_010677.1 82386 83246 D galactose mutarotase 82386..83246 Francisella tularensis subsp. mediasiatica FSC147 6290972 YP_001890958.1 CDS purB NC_010677.1 85014 86312 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 85014..86312 Francisella tularensis subsp. mediasiatica FSC147 6290695 YP_001890959.1 CDS FTM_0080 NC_010677.1 86284 86925 D hypothetical protein 86284..86925 Francisella tularensis subsp. mediasiatica FSC147 6290733 YP_001890960.1 CDS FTM_0081 NC_010677.1 87012 88553 D ATP-binding cassette 87012..88553 Francisella tularensis subsp. mediasiatica FSC147 6290751 YP_001890961.1 CDS FTM_0082 NC_010677.1 88564 89634 D membrane-fusion protein 88564..89634 Francisella tularensis subsp. mediasiatica FSC147 6291528 YP_001890962.1 CDS gatC NC_010677.1 89717 89998 D glutamyl-tRNA(Gln) amidotransferase subunit C 89717..89998 Francisella tularensis subsp. mediasiatica FSC147 6290703 YP_001890963.1 CDS gatA NC_010677.1 90007 91452 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 90007..91452 Francisella tularensis subsp. mediasiatica FSC147 6291177 YP_001890964.1 CDS gatB NC_010677.1 91455 92876 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 91455..92876 Francisella tularensis subsp. mediasiatica FSC147 6290764 YP_001890965.1 CDS FTM_0086 NC_010677.1 92891 93298 D hypothetical protein 92891..93298 Francisella tularensis subsp. mediasiatica FSC147 6291115 YP_001890966.1 CDS FTM_0088 NC_010677.1 94855 96384 R membrane protein complement(94855..96384) Francisella tularensis subsp. mediasiatica FSC147 6290247 YP_001890967.1 CDS FTM_0089 NC_010677.1 96470 97660 R drug:H+ antiporter-1 complement(96470..97660) Francisella tularensis subsp. mediasiatica FSC147 6290468 YP_001890968.1 CDS FTM_0090 NC_010677.1 97676 98929 R diaminopimelate decarboxylase complement(97676..98929) Francisella tularensis subsp. mediasiatica FSC147 6291504 YP_001890969.1 CDS FTM_0091 NC_010677.1 98922 100184 R drug:H+ antiporter-1 complement(98922..100184) Francisella tularensis subsp. mediasiatica FSC147 6290854 YP_001890970.1 CDS frgA NC_010677.1 100191 102110 R siderophore biosynthesis protein complement(100191..102110) Francisella tularensis subsp. mediasiatica FSC147 6291131 YP_001890971.1 CDS fur NC_010677.1 102363 102785 R ferric uptake regulation protein complement(102363..102785) Francisella tularensis subsp. mediasiatica FSC147 6290677 YP_001890972.1 CDS nuoA NC_010677.1 102993 103391 D NADH dehydrogenase I subunit A 102993..103391 Francisella tularensis subsp. mediasiatica FSC147 6290047 YP_001890973.1 CDS nuoB NC_010677.1 103382 103858 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 103382..103858 Francisella tularensis subsp. mediasiatica FSC147 6291122 YP_001890974.1 CDS nuoC NC_010677.1 103861 104505 D NADH dehydrogenase I subunit C 103861..104505 Francisella tularensis subsp. mediasiatica FSC147 6291447 YP_001890975.1 CDS nuoD NC_010677.1 104527 105780 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 104527..105780 Francisella tularensis subsp. mediasiatica FSC147 6290629 YP_001890976.1 CDS nuoE NC_010677.1 105790 106278 D NADH dehydrogenase I subunit E 105790..106278 Francisella tularensis subsp. mediasiatica FSC147 6291505 YP_001890977.1 CDS nuoF NC_010677.1 106285 107559 D NADH dehydrogenase I subunit F 106285..107559 Francisella tularensis subsp. mediasiatica FSC147 6290644 YP_001890978.1 CDS nuoG NC_010677.1 107577 109943 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 107577..109943 Francisella tularensis subsp. mediasiatica FSC147 6290633 YP_001890979.1 CDS nuoH NC_010677.1 109945 110955 D NADH dehydrogenase I subunit H 109945..110955 Francisella tularensis subsp. mediasiatica FSC147 6290634 YP_001890980.1 CDS nuoI NC_010677.1 110969 111457 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 110969..111457 Francisella tularensis subsp. mediasiatica FSC147 6290377 YP_001890981.1 CDS nuoJ NC_010677.1 111462 112067 D NADH dehydrogenase I subunit J 111462..112067 Francisella tularensis subsp. mediasiatica FSC147 6290161 YP_001890982.1 CDS nuoK NC_010677.1 112060 112377 D NADH dehydrogenase I subunit K 112060..112377 Francisella tularensis subsp. mediasiatica FSC147 6290339 YP_001890983.1 CDS nuoL NC_010677.1 112387 114396 D NADH dehydrogenase I subunit L 112387..114396 Francisella tularensis subsp. mediasiatica FSC147 6290832 YP_001890984.1 CDS nuoM NC_010677.1 114422 116011 D NADH dehydrogenase I subunit M 114422..116011 Francisella tularensis subsp. mediasiatica FSC147 6290805 YP_001890985.1 CDS nuoN NC_010677.1 116027 117478 D NADH dehydrogenase I subunit N 116027..117478 Francisella tularensis subsp. mediasiatica FSC147 6291488 YP_001890986.1 CDS FTM_0108 NC_010677.1 117554 117748 D hypothetical protein 117554..117748 Francisella tularensis subsp. mediasiatica FSC147 6290910 YP_001890987.1 CDS hemE NC_010677.1 119311 120345 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 119311..120345 Francisella tularensis subsp. mediasiatica FSC147 6290887 YP_001890988.1 CDS FTM_0112 NC_010677.1 120571 121023 D hypothetical protein 120571..121023 Francisella tularensis subsp. mediasiatica FSC147 6290309 YP_001890989.1 CDS nusA NC_010677.1 121041 122510 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 121041..122510 Francisella tularensis subsp. mediasiatica FSC147 6290933 YP_001890990.1 CDS infB NC_010677.1 122549 125089 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 122549..125089 Francisella tularensis subsp. mediasiatica FSC147 6290237 YP_001890991.1 CDS rbfA NC_010677.1 125092 125523 D ribosome-binding factor A 125092..125523 Francisella tularensis subsp. mediasiatica FSC147 6290698 YP_001890992.1 CDS hisS NC_010677.1 125531 126796 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 125531..126796 Francisella tularensis subsp. mediasiatica FSC147 6290568 YP_001890993.1 CDS FTM_0117 NC_010677.1 126803 128101 D major facilitator superfamily protein 126803..128101 Francisella tularensis subsp. mediasiatica FSC147 6290765 YP_001890994.1 CDS FTM_0118 NC_010677.1 128104 129171 D ATPase 128104..129171 Francisella tularensis subsp. mediasiatica FSC147 6290518 YP_001890995.1 CDS rluC NC_010677.1 129164 130093 D ribosomal large subunit pseudouridine synthase C 129164..130093 Francisella tularensis subsp. mediasiatica FSC147 6291198 YP_001890996.1 CDS FTM_0120 NC_010677.1 130095 131399 R major facilitator superfamily protein complement(130095..131399) Francisella tularensis subsp. mediasiatica FSC147 6291194 YP_001890997.1 CDS FTM_0121 NC_010677.1 131476 131907 D membrane protein 131476..131907 Francisella tularensis subsp. mediasiatica FSC147 6291423 YP_001890998.1 CDS atpB NC_010677.1 131960 132751 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 131960..132751 Francisella tularensis subsp. mediasiatica FSC147 6290228 YP_001890999.1 CDS atpE NC_010677.1 132802 133107 D produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 132802..133107 Francisella tularensis subsp. mediasiatica FSC147 6290732 YP_001891000.1 CDS atpF NC_010677.1 133153 133623 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 133153..133623 Francisella tularensis subsp. mediasiatica FSC147 6290205 YP_001891001.1 CDS atpH NC_010677.1 133643 134167 D Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 133643..134167 Francisella tularensis subsp. mediasiatica FSC147 6290293 YP_001891002.1 CDS atpA NC_010677.1 134186 135727 D produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 134186..135727 Francisella tularensis subsp. mediasiatica FSC147 6290651 YP_001891003.1 CDS atpG NC_010677.1 135742 136638 D produces ATP from ADP in the presence of a proton gradient across the membrane; the gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 135742..136638 Francisella tularensis subsp. mediasiatica FSC147 6291293 YP_001891004.1 CDS atpD NC_010677.1 136648 138024 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 136648..138024 Francisella tularensis subsp. mediasiatica FSC147 6290360 YP_001891005.1 CDS atpC NC_010677.1 138037 138474 D produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon 138037..138474 Francisella tularensis subsp. mediasiatica FSC147 6290959 YP_001891006.1 CDS FTM_0130 NC_010677.1 138685 141528 D hypothetical protein 138685..141528 Francisella tularensis subsp. mediasiatica FSC147 6291000 YP_001891007.1 CDS FTM_0131 NC_010677.1 141545 141874 R glutaredoxin-like protein complement(141545..141874) Francisella tularensis subsp. mediasiatica FSC147 6291112 YP_001891008.1 CDS sodB NC_010677.1 142010 142588 D iron/manganese superoxide dismutase family protein 142010..142588 Francisella tularensis subsp. mediasiatica FSC147 6291328 YP_001891009.1 CDS FTM_0133 NC_010677.1 142600 142788 D hypothetical protein 142600..142788 Francisella tularensis subsp. mediasiatica FSC147 6291586 YP_001891010.1 CDS ampG NC_010677.1 142793 144058 R peptide-acetyl-coenzyme A transporter (PAT) family protein complement(142793..144058) Francisella tularensis subsp. mediasiatica FSC147 6291671 YP_001891011.1 CDS gltA NC_010677.1 144148 145407 R citrate synthase I complement(144148..145407) Francisella tularensis subsp. mediasiatica FSC147 6291165 YP_001891012.1 CDS sdhC NC_010677.1 145665 146138 D succinate dehydrogenase, cytochrome b556 subunit 145665..146138 Francisella tularensis subsp. mediasiatica FSC147 6290475 YP_001891013.1 CDS sdhD NC_010677.1 146114 146482 D succinate dehydrogenase, hydrophobic membrane anchor protein 146114..146482 Francisella tularensis subsp. mediasiatica FSC147 6291254 YP_001891014.1 CDS sdhA NC_010677.1 146495 148288 D succinate dehydrogenase, flavoprotein subunit 146495..148288 Francisella tularensis subsp. mediasiatica FSC147 6290984 YP_001891015.1 CDS sdhB NC_010677.1 148306 149007 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 148306..149007 Francisella tularensis subsp. mediasiatica FSC147 6291540 YP_001891016.1 CDS sucA NC_010677.1 149037 151850 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 149037..151850 Francisella tularensis subsp. mediasiatica FSC147 6290849 YP_001891017.1 CDS sucB NC_010677.1 151876 153345 D 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 151876..153345 Francisella tularensis subsp. mediasiatica FSC147 6290808 YP_001891018.1 CDS apt NC_010677.1 153385 153912 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 153385..153912 Francisella tularensis subsp. mediasiatica FSC147 6290574 YP_001891019.1 CDS glmM NC_010677.1 153923 155254 D catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 153923..155254 Francisella tularensis subsp. mediasiatica FSC147 6290434 YP_001891020.1 CDS tpiA NC_010677.1 155257 156018 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 155257..156018 Francisella tularensis subsp. mediasiatica FSC147 6291134 YP_001891021.1 CDS secG NC_010677.1 156006 156359 D preprotein translocase subunit SecG 156006..156359 Francisella tularensis subsp. mediasiatica FSC147 6290834 YP_001891022.1 CDS hemN NC_010677.1 158036 159178 R coproporphyrinogen III oxidase, anaerobic complement(158036..159178) Francisella tularensis subsp. mediasiatica FSC147 6291398 YP_001891023.1 CDS FTM_0150 NC_010677.1 159183 159560 R GtrA-like protein complement(159183..159560) Francisella tularensis subsp. mediasiatica FSC147 6290576 YP_001891024.1 CDS FTM_0151 NC_010677.1 159630 160508 D iron-dependent peroxidase 159630..160508 Francisella tularensis subsp. mediasiatica FSC147 6290664 YP_001891025.1 CDS acnA NC_010677.1 160613 163426 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 160613..163426 Francisella tularensis subsp. mediasiatica FSC147 6290445 YP_001891026.1 CDS FTM_0155 NC_010677.1 166432 166878 R hypothetical protein complement(166432..166878) Francisella tularensis subsp. mediasiatica FSC147 6290783 YP_001891027.1 CDS FTM_0158 NC_010677.1 169467 170348 D NAD dependent epimerase/dehydratase family 169467..170348 Francisella tularensis subsp. mediasiatica FSC147 6290702 YP_001891028.1 CDS FTM_0159 NC_010677.1 170345 171772 R two-component regulator, sensor histidine kinase complement(170345..171772) Francisella tularensis subsp. mediasiatica FSC147 6290069 YP_001891029.1 CDS FTM_0162 NC_010677.1 174285 174806 D hypothetical protein 174285..174806 Francisella tularensis subsp. mediasiatica FSC147 6290310 YP_001891030.1 CDS FTM_0164 NC_010677.1 177103 178116 D peptidase, U61 family 177103..178116 Francisella tularensis subsp. mediasiatica FSC147 6290573 YP_001891031.1 CDS FTM_0165 NC_010677.1 179561 180142 R transposase, IS4 family protein complement(179561..180142) Francisella tularensis subsp. mediasiatica FSC147 6290495 YP_001891032.1 CDS FTM_0166 NC_010677.1 180384 181664 R major facilitator superfamily protein complement(180384..181664) Francisella tularensis subsp. mediasiatica FSC147 6290396 YP_001891033.1 CDS FTM_0167 NC_010677.1 181784 184897 R transporter, AcrB/AcrD/AcrF family complement(181784..184897) Francisella tularensis subsp. mediasiatica FSC147 6290987 YP_001891034.1 CDS FTM_0168 NC_010677.1 184897 186270 R membrane fusion protein complement(184897..186270) Francisella tularensis subsp. mediasiatica FSC147 6291436 YP_001891035.1 CDS dsbB NC_010677.1 186283 186774 R disulfide bond formation protein complement(186283..186774) Francisella tularensis subsp. mediasiatica FSC147 6290255 YP_001891036.1 CDS cca NC_010677.1 186814 187896 R catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase complement(186814..187896) Francisella tularensis subsp. mediasiatica FSC147 6291168 YP_001891037.1 CDS msbA NC_010677.1 188001 189830 D lipid A export permease/ATP-binding protein MsbA 188001..189830 Francisella tularensis subsp. mediasiatica FSC147 6290571 YP_001891038.1 CDS lpxK NC_010677.1 189836 190804 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 189836..190804 Francisella tularensis subsp. mediasiatica FSC147 6291251 YP_001891039.1 CDS polA NC_010677.1 190900 193593 D DNA polymerase I 190900..193593 Francisella tularensis subsp. mediasiatica FSC147 6290271 YP_001891040.1 CDS FTM_0174 NC_010677.1 193613 194389 D type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 193613..194389 Francisella tularensis subsp. mediasiatica FSC147 6291256 YP_001891041.1 CDS deoB NC_010677.1 194394 195638 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 194394..195638 Francisella tularensis subsp. mediasiatica FSC147 6291514 YP_001891042.1 CDS deoC NC_010677.1 195601 196362 D deoxyribose-phosphate aldolase 195601..196362 Francisella tularensis subsp. mediasiatica FSC147 6290640 YP_001891043.1 CDS nupC1 NC_010677.1 196352 197551 D nucleoside permease NupC 196352..197551 Francisella tularensis subsp. mediasiatica FSC147 6291281 YP_001891044.1 CDS nupC NC_010677.1 197570 198772 D nucleoside permease NupC 197570..198772 Francisella tularensis subsp. mediasiatica FSC147 6290393 YP_001891045.1 CDS tmk NC_010677.1 198785 199414 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 198785..199414 Francisella tularensis subsp. mediasiatica FSC147 6291568 YP_001891046.1 CDS prfC NC_010677.1 199476 201053 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 199476..201053 Francisella tularensis subsp. mediasiatica FSC147 6290759 YP_001891047.1 CDS fimV NC_010677.1 201128 202447 D type IV pili, pilus assembly protein 201128..202447 Francisella tularensis subsp. mediasiatica FSC147 6290373 YP_001891048.1 CDS ftsY NC_010677.1 202480 203475 D signal recognition particle-docking protein FtsY 202480..203475 Francisella tularensis subsp. mediasiatica FSC147 6291352 YP_001891049.1 CDS uvrD NC_010677.1 203566 205788 D DNA helicase II 203566..205788 Francisella tularensis subsp. mediasiatica FSC147 6290848 YP_001891050.1 CDS FTM_0184 NC_010677.1 205907 207475 D oligopeptide ABC transporter periplasmic protein 205907..207475 Francisella tularensis subsp. mediasiatica FSC147 6290454 YP_001891051.1 CDS oppD NC_010677.1 209380 210348 D peptide/opine/nickel uptake transporter (PepT) family protein 209380..210348 Francisella tularensis subsp. mediasiatica FSC147 6291498 YP_001891052.1 CDS FTM_0189 NC_010677.1 211326 212528 R major facilitator superfamily protein complement(211326..212528) Francisella tularensis subsp. mediasiatica FSC147 6291086 YP_001891053.1 CDS FTM_0190 NC_010677.1 212662 213243 D hypothetical protein 212662..213243 Francisella tularensis subsp. mediasiatica FSC147 6291014 YP_001891054.1 CDS FTM_0191 NC_010677.1 213342 214655 D sugar transporter, MFS superfamily 213342..214655 Francisella tularensis subsp. mediasiatica FSC147 6290753 YP_001891055.1 CDS glpK NC_010677.1 214712 216220 D glycerol kinase 214712..216220 Francisella tularensis subsp. mediasiatica FSC147 6291474 YP_001891056.1 CDS glpD NC_010677.1 217283 218815 D glycerol-3-phosphate dehydrogenase 217283..218815 Francisella tularensis subsp. mediasiatica FSC147 6291416 YP_001891057.1 CDS glpF NC_010677.1 218825 219589 D glycerol uptake facilitator protein 218825..219589 Francisella tularensis subsp. mediasiatica FSC147 6290723 YP_001891058.1 CDS FTM_0195 NC_010677.1 219593 220306 D membrane protein 219593..220306 Francisella tularensis subsp. mediasiatica FSC147 6291706 YP_001891059.1 CDS FTM_0196 NC_010677.1 220284 220781 D small conductance mechanosensitive ion channel (MscS) family protein 220284..220781 Francisella tularensis subsp. mediasiatica FSC147 6291611 YP_001891060.1 CDS tufA NC_010677.1 222659 223843 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 222659..223843 Francisella tularensis subsp. mediasiatica FSC147 6290303 YP_001891061.1 CDS secE NC_010677.1 224036 224506 D forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 224036..224506 Francisella tularensis subsp. mediasiatica FSC147 6290966 YP_001891062.1 CDS nusG NC_010677.1 224522 225055 D transcription termination/antitermination factor NusG 224522..225055 Francisella tularensis subsp. mediasiatica FSC147 6291087 YP_001891063.1 CDS rplK NC_010677.1 225125 225559 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 225125..225559 Francisella tularensis subsp. mediasiatica FSC147 6290334 YP_001891064.1 CDS rplA NC_010677.1 225562 226257 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 225562..226257 Francisella tularensis subsp. mediasiatica FSC147 6290762 YP_001891065.1 CDS rplJ NC_010677.1 226427 226945 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 226427..226945 Francisella tularensis subsp. mediasiatica FSC147 6291613 YP_001891066.1 CDS rplL NC_010677.1 227008 227388 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 227008..227388 Francisella tularensis subsp. mediasiatica FSC147 6291579 YP_001891067.1 CDS rpoB NC_010677.1 227542 231618 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 227542..231618 Francisella tularensis subsp. mediasiatica FSC147 6291615 YP_001891068.1 CDS rpoC NC_010677.1 231680 235933 D DNA-directed RNA polymerase subunit beta' 231680..235933 Francisella tularensis subsp. mediasiatica FSC147 6290545 YP_001891069.1 CDS FTM_0211 NC_010677.1 236036 236272 D membrane protein 236036..236272 Francisella tularensis subsp. mediasiatica FSC147 6290821 YP_001891070.1 CDS gcp NC_010677.1 236272 237282 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 236272..237282 Francisella tularensis subsp. mediasiatica FSC147 6290867 YP_001891071.1 CDS FTM_0213 NC_010677.1 237396 238562 D fatty acid desaturase 237396..238562 Francisella tularensis subsp. mediasiatica FSC147 6290222 YP_001891072.1 CDS metK NC_010677.1 238774 239934 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(238774..239934) Francisella tularensis subsp. mediasiatica FSC147 6290868 YP_001891073.1 CDS rpsP NC_010677.1 240228 240476 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 240228..240476 Francisella tularensis subsp. mediasiatica FSC147 6291210 YP_001891074.1 CDS rimM NC_010677.1 240519 241028 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 240519..241028 Francisella tularensis subsp. mediasiatica FSC147 6291374 YP_001891075.1 CDS trmD NC_010677.1 241431 242189 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 241431..242189 Francisella tularensis subsp. mediasiatica FSC147 6290685 YP_001891076.1 CDS rplS NC_010677.1 242189 242536 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 242189..242536 Francisella tularensis subsp. mediasiatica FSC147 6290213 YP_001891077.1 CDS xerD NC_010677.1 242702 243580 D tyrosine recombinase XerD 242702..243580 Francisella tularensis subsp. mediasiatica FSC147 6291390 YP_001891078.1 CDS FTM_0221 NC_010677.1 244554 245138 D acid phosphatase, HAD superfamily protein 244554..245138 Francisella tularensis subsp. mediasiatica FSC147 6291149 YP_001891079.1 CDS FTM_0224 NC_010677.1 247820 248287 D hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 247820..248287 Francisella tularensis subsp. mediasiatica FSC147 6290935 YP_001891080.1 CDS nudH NC_010677.1 248297 248923 R dGTP pyrophosphohydrolase complement(248297..248923) Francisella tularensis subsp. mediasiatica FSC147 6290300 YP_001891081.1 CDS ampD NC_010677.1 248997 249521 D N-acetyl-anhydromuranmyl-L-alanine amidase 248997..249521 Francisella tularensis subsp. mediasiatica FSC147 6291559 YP_001891082.1 CDS parE NC_010677.1 249569 251452 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(249569..251452) Francisella tularensis subsp. mediasiatica FSC147 6290461 YP_001891083.1 CDS FTM_0228 NC_010677.1 251543 252724 R drug:H+ antiporter-1 (DHA1) family protein complement(251543..252724) Francisella tularensis subsp. mediasiatica FSC147 6290277 YP_001891084.1 CDS FTM_0229 NC_010677.1 252724 254094 R outer membrane assembly lipoprotein YfgL complement(252724..254094) Francisella tularensis subsp. mediasiatica FSC147 6290649 YP_001891085.1 CDS FTM_0230 NC_010677.1 254097 254735 R hypothetical protein complement(254097..254735) Francisella tularensis subsp. mediasiatica FSC147 6291315 YP_001891086.1 CDS hemA NC_010677.1 254915 256159 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 254915..256159 Francisella tularensis subsp. mediasiatica FSC147 6290352 YP_001891087.1 CDS prfA NC_010677.1 256160 257245 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 256160..257245 Francisella tularensis subsp. mediasiatica FSC147 6290270 YP_001891088.1 CDS hemK NC_010677.1 257238 258092 D HemK family modification methylase 257238..258092 Francisella tularensis subsp. mediasiatica FSC147 6290811 YP_001891089.1 CDS groEL NC_010677.1 259511 261145 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(259511..261145) Francisella tularensis subsp. mediasiatica FSC147 6290555 YP_001891090.1 CDS groES NC_010677.1 261183 261470 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(261183..261470) Francisella tularensis subsp. mediasiatica FSC147 6291636 YP_001891091.1 CDS FTM_0237 NC_010677.1 261720 262154 D hypothetical protein 261720..262154 Francisella tularensis subsp. mediasiatica FSC147 6291486 YP_001891092.1 CDS FTM_0239 NC_010677.1 262795 263559 D hypothetical protein 262795..263559 Francisella tularensis subsp. mediasiatica FSC147 6290337 YP_001891093.1 CDS proQ NC_010677.1 266052 266753 D activator of osmoprotectant transporter ProP 266052..266753 Francisella tularensis subsp. mediasiatica FSC147 6291100 YP_001891094.1 CDS FTM_0244 NC_010677.1 266776 267321 D hypothetical protein 266776..267321 Francisella tularensis subsp. mediasiatica FSC147 6290264 YP_001891095.1 CDS trkH NC_010677.1 267336 268790 R K+ transporter (Trk) family protein complement(267336..268790) Francisella tularensis subsp. mediasiatica FSC147 6291072 YP_001891096.1 CDS FTM_0246 NC_010677.1 268902 269105 D hypothetical protein 268902..269105 Francisella tularensis subsp. mediasiatica FSC147 6291468 YP_001891097.1 CDS lolA NC_010677.1 269487 270104 R lipoprotein releasing system, subunit A, outer membrane lipoproteins carrier complement(269487..270104) Francisella tularensis subsp. mediasiatica FSC147 6291424 YP_001891098.1 CDS ftsK NC_010677.1 270105 272600 R cell division protein FtsK complement(270105..272600) Francisella tularensis subsp. mediasiatica FSC147 6291592 YP_001891099.1 CDS FTM_0249 NC_010677.1 272722 273390 D phosphatidic acid phosphatase, PAP2 superfamily 272722..273390 Francisella tularensis subsp. mediasiatica FSC147 6290988 YP_001891100.1 CDS lysP NC_010677.1 273637 275091 D lysine:H+ symporter 273637..275091 Francisella tularensis subsp. mediasiatica FSC147 6291632 YP_001891101.1 CDS FTM_0251 NC_010677.1 275100 275738 D hypothetical protein 275100..275738 Francisella tularensis subsp. mediasiatica FSC147 6291581 YP_001891102.1 CDS glpX NC_010677.1 275758 276744 D type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 275758..276744 Francisella tularensis subsp. mediasiatica FSC147 6291267 YP_001891103.1 CDS FTM_0254 NC_010677.1 278587 280266 D glycosyl transferase 278587..280266 Francisella tularensis subsp. mediasiatica FSC147 6290758 YP_001891104.1 CDS FTM_0255 NC_010677.1 280277 281584 D transporter-associated protein, HlyC/CorC family 280277..281584 Francisella tularensis subsp. mediasiatica FSC147 6291618 YP_001891105.1 CDS FTM_0256 NC_010677.1 281655 282002 D hypothetical protein 281655..282002 Francisella tularensis subsp. mediasiatica FSC147 6291321 YP_001891106.1 CDS FTM_0259 NC_010677.1 284318 284938 D pilus assembly protein 284318..284938 Francisella tularensis subsp. mediasiatica FSC147 6291458 YP_001891107.1 CDS FTM_0263 NC_010677.1 288762 289253 R acetyltransferase complement(288762..289253) Francisella tularensis subsp. mediasiatica FSC147 6291399 YP_001891108.1 CDS FTM_0264 NC_010677.1 289279 290457 R drug:H+ antiporter-1 complement(289279..290457) Francisella tularensis subsp. mediasiatica FSC147 6290844 YP_001891109.1 CDS FTM_0265 NC_010677.1 290513 291457 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(290513..291457) Francisella tularensis subsp. mediasiatica FSC147 6290379 YP_001891110.1 CDS cysS NC_010677.1 291461 292840 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(291461..292840) Francisella tularensis subsp. mediasiatica FSC147 6291324 YP_001891111.1 CDS FTM_0269 NC_010677.1 294289 294570 R membrane protein complement(294289..294570) Francisella tularensis subsp. mediasiatica FSC147 6291178 YP_001891112.1 CDS FTM_0270 NC_010677.1 294583 296085 R amino acid-polyamine-organocation family protein complement(294583..296085) Francisella tularensis subsp. mediasiatica FSC147 6291249 YP_001891113.1 CDS FTM_0271 NC_010677.1 296450 297193 R hypothetical protein complement(296450..297193) Francisella tularensis subsp. mediasiatica FSC147 6290239 YP_001891114.1 CDS ubiG NC_010677.1 297195 297890 R Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase complement(297195..297890) Francisella tularensis subsp. mediasiatica FSC147 6291037 YP_001891115.1 CDS FTM_0273 NC_010677.1 298032 299132 D VacJ family protein 298032..299132 Francisella tularensis subsp. mediasiatica FSC147 6290378 YP_001891116.1 CDS FTM_0277 NC_010677.1 304236 304961 D hypothetical protein 304236..304961 Francisella tularensis subsp. mediasiatica FSC147 6291141 YP_001891117.1 CDS FTM_0281 NC_010677.1 311395 311865 D hypothetical protein 311395..311865 Francisella tularensis subsp. mediasiatica FSC147 6291183 YP_001891118.1 CDS FTM_0282 NC_010677.1 312002 312826 D short-chain dehydrogenase/reductase 312002..312826 Francisella tularensis subsp. mediasiatica FSC147 6290625 YP_001891119.1 CDS FTM_0283 NC_010677.1 312848 314197 R amino acid-polyamine-organocation (APC) superfamily protein complement(312848..314197) Francisella tularensis subsp. mediasiatica FSC147 6290705 YP_001891120.1 CDS FTM_0284 NC_010677.1 314456 315328 R hypothetical protein complement(314456..315328) Francisella tularensis subsp. mediasiatica FSC147 6291604 YP_001891121.1 CDS FTM_0285 NC_010677.1 316274 316723 R hypothetical protein complement(316274..316723) Francisella tularensis subsp. mediasiatica FSC147 6291160 YP_001891122.1 CDS FTM_0286 NC_010677.1 316732 317127 R hypothetical protein complement(316732..317127) Francisella tularensis subsp. mediasiatica FSC147 6291235 YP_001891123.1 CDS FTM_0287 NC_010677.1 317210 317941 D oxidoreductase 317210..317941 Francisella tularensis subsp. mediasiatica FSC147 6291464 YP_001891124.1 CDS rpmE NC_010677.1 318063 318278 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 318063..318278 Francisella tularensis subsp. mediasiatica FSC147 6290323 YP_001891125.1 CDS gshA NC_010677.1 318489 319994 R glutamate-cysteine ligase complement(318489..319994) Francisella tularensis subsp. mediasiatica FSC147 6290212 YP_001891126.1 CDS mviN NC_010677.1 320047 321588 R multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) transporter complement(320047..321588) Francisella tularensis subsp. mediasiatica FSC147 6290838 YP_001891127.1 CDS FTM_0291 NC_010677.1 321611 322672 R hypothetical protein complement(321611..322672) Francisella tularensis subsp. mediasiatica FSC147 6290913 YP_001891128.1 CDS FTM_0292 NC_010677.1 322755 323165 R hypothetical protein complement(322755..323165) Francisella tularensis subsp. mediasiatica FSC147 6291492 YP_001891129.1 CDS folC NC_010677.1 323143 324324 R folylpoly-gamma-glutamate synthetase/ dihydrofolate synthetase complement(323143..324324) Francisella tularensis subsp. mediasiatica FSC147 6291167 YP_001891130.1 CDS accD NC_010677.1 324339 325241 R acetyl-CoA carboxylase, carboxyl transferase subunit beta complement(324339..325241) Francisella tularensis subsp. mediasiatica FSC147 6291022 YP_001891131.1 CDS ndk NC_010677.1 325283 325705 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(325283..325705) Francisella tularensis subsp. mediasiatica FSC147 6290365 YP_001891132.1 CDS pyrG NC_010677.1 325778 327418 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(325778..327418) Francisella tularensis subsp. mediasiatica FSC147 6290575 YP_001891133.1 CDS FTM_0298 NC_010677.1 329475 330431 R membrane protein complement(329475..330431) Francisella tularensis subsp. mediasiatica FSC147 6290816 YP_001891134.1 CDS FTM_0299 NC_010677.1 332556 333521 D glycosyltransferase sugar-binding region containing DXD motif family 332556..333521 Francisella tularensis subsp. mediasiatica FSC147 6291499 YP_001891135.1 CDS htpG NC_010677.1 334630 336516 D molecular chaperone; heat shock protein 90 334630..336516 Francisella tularensis subsp. mediasiatica FSC147 6290281 YP_001891136.1 CDS fumA NC_010677.1 337979 339493 R fumarate hydratase, class I complement(337979..339493) Francisella tularensis subsp. mediasiatica FSC147 6290444 YP_001891137.1 CDS FTM_0302 NC_010677.1 340045 340242 R hypothetical protein complement(340045..340242) Francisella tularensis subsp. mediasiatica FSC147 6291154 YP_001891138.1 CDS recG NC_010677.1 340246 342285 R ATP-dependent DNA helicase RecG complement(340246..342285) Francisella tularensis subsp. mediasiatica FSC147 6291649 YP_001891139.1 CDS FTM_0304 NC_010677.1 342415 342759 D hypothetical protein 342415..342759 Francisella tularensis subsp. mediasiatica FSC147 6290862 YP_001891140.1 CDS rpmB NC_010677.1 342894 343130 D required for 70S ribosome assembly; 50S ribosomal protein L28 342894..343130 Francisella tularensis subsp. mediasiatica FSC147 6291215 YP_001891141.1 CDS rpmG NC_010677.1 343157 343312 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 343157..343312 Francisella tularensis subsp. mediasiatica FSC147 6291537 YP_001891142.1 CDS minC NC_010677.1 343347 344033 D septum formation inhibitor 343347..344033 Francisella tularensis subsp. mediasiatica FSC147 6291005 YP_001891143.1 CDS minD NC_010677.1 344073 344897 D septum formation inhibitor-activating ATPase 344073..344897 Francisella tularensis subsp. mediasiatica FSC147 6290250 YP_001891144.1 CDS minE NC_010677.1 344900 345172 D works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 344900..345172 Francisella tularensis subsp. mediasiatica FSC147 6290768 YP_001891145.1 CDS FTM_0310 NC_010677.1 345186 345989 D ABC transporter ATP-binding protein 345186..345989 Francisella tularensis subsp. mediasiatica FSC147 6291312 YP_001891146.1 CDS FTM_0311 NC_010677.1 345993 346757 D ABC-type transport system permease protein 345993..346757 Francisella tularensis subsp. mediasiatica FSC147 6291577 YP_001891147.1 CDS FTM_0312 NC_010677.1 346757 347290 D ABC transporter substrate-binding protein 346757..347290 Francisella tularensis subsp. mediasiatica FSC147 6290922 YP_001891148.1 CDS FTM_0313 NC_010677.1 347364 348026 D hypothetical protein 347364..348026 Francisella tularensis subsp. mediasiatica FSC147 6291331 YP_001891149.1 CDS FTM_0314 NC_010677.1 348026 348319 D hypothetical protein 348026..348319 Francisella tularensis subsp. mediasiatica FSC147 6291371 YP_001891150.1 CDS FTM_0315 NC_010677.1 348336 348572 D BolA family protein 348336..348572 Francisella tularensis subsp. mediasiatica FSC147 6291419 YP_001891151.1 CDS FTM_0319 NC_010677.1 353138 353638 D hypothetical protein 353138..353638 Francisella tularensis subsp. mediasiatica FSC147 6290840 YP_001891152.1 CDS FTM_0320 NC_010677.1 353839 356565 D type III restriction enzyme 353839..356565 Francisella tularensis subsp. mediasiatica FSC147 6291516 YP_001891153.1 CDS ung NC_010677.1 356562 357224 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 356562..357224 Francisella tularensis subsp. mediasiatica FSC147 6291028 YP_001891154.1 CDS gyrA NC_010677.1 359184 361790 D DNA gyrase subunit A 359184..361790 Francisella tularensis subsp. mediasiatica FSC147 6291067 YP_001891155.1 CDS dxr NC_010677.1 361796 362953 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 361796..362953 Francisella tularensis subsp. mediasiatica FSC147 6290418 YP_001891156.1 CDS FTM_0325 NC_010677.1 362959 365337 D hypothetical protein 362959..365337 Francisella tularensis subsp. mediasiatica FSC147 6290543 YP_001891157.1 CDS ompH NC_010677.1 365473 365976 D outer membrane protein OmpH 365473..365976 Francisella tularensis subsp. mediasiatica FSC147 6290879 YP_001891158.1 CDS lpxD NC_010677.1 365995 367008 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 365995..367008 Francisella tularensis subsp. mediasiatica FSC147 6291542 YP_001891159.1 CDS fabZ NC_010677.1 367023 367514 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 367023..367514 Francisella tularensis subsp. mediasiatica FSC147 6291157 YP_001891160.1 CDS lpxA NC_010677.1 367517 368296 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 367517..368296 Francisella tularensis subsp. mediasiatica FSC147 6290678 YP_001891161.1 CDS lpxB NC_010677.1 368296 369438 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 368296..369438 Francisella tularensis subsp. mediasiatica FSC147 6290459 YP_001891162.1 CDS FTM_0331 NC_010677.1 369497 370084 D membrane protein 369497..370084 Francisella tularensis subsp. mediasiatica FSC147 6291633 YP_001891163.1 CDS FTM_0332 NC_010677.1 370175 370549 D hypothetical protein 370175..370549 Francisella tularensis subsp. mediasiatica FSC147 6291225 YP_001891164.1 CDS FTM_0335 NC_010677.1 372346 373155 R polyphosphate kinase 2 complement(372346..373155) Francisella tularensis subsp. mediasiatica FSC147 6291430 YP_001891165.1 CDS pcs NC_010677.1 373225 373989 R (CDP-alcohol) phosphatidyltransferase complement(373225..373989) Francisella tularensis subsp. mediasiatica FSC147 6290713 YP_001891166.1 CDS ispA NC_010677.1 374037 374918 R geranyl diphosphate synthase/farnesyl diphosphate synthase complement(374037..374918) Francisella tularensis subsp. mediasiatica FSC147 6290742 YP_001891167.1 CDS kdtA NC_010677.1 374915 376210 R 3-deoxy-D-manno-octulosonic-acid transferase complement(374915..376210) Francisella tularensis subsp. mediasiatica FSC147 6290819 YP_001891168.1 CDS FTM_0339 NC_010677.1 376315 376893 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase complement(376315..376893) Francisella tularensis subsp. mediasiatica FSC147 6291201 YP_001891169.1 CDS proC NC_010677.1 377000 377797 D pyrroline-5-carboxylate reductase 377000..377797 Francisella tularensis subsp. mediasiatica FSC147 6290374 YP_001891170.1 CDS FTM_0342 NC_010677.1 379560 380246 D two-component response regulator 379560..380246 Francisella tularensis subsp. mediasiatica FSC147 6290565 YP_001891171.1 CDS lepB NC_010677.1 380251 381114 D signal peptidase I 380251..381114 Francisella tularensis subsp. mediasiatica FSC147 6291325 YP_001891172.1 CDS rnc NC_010677.1 381121 381813 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 381121..381813 Francisella tularensis subsp. mediasiatica FSC147 6290804 YP_001891173.1 CDS truB NC_010677.1 381800 382708 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 381800..382708 Francisella tularensis subsp. mediasiatica FSC147 6291500 YP_001891174.1 CDS rnr NC_010677.1 382701 384998 D ribonuclease R 382701..384998 Francisella tularensis subsp. mediasiatica FSC147 6290598 YP_001891175.1 CDS FTM_0348 NC_010677.1 385455 386198 R oxidoreductase complement(385455..386198) Francisella tularensis subsp. mediasiatica FSC147 6290752 YP_001891176.1 CDS FTM_0350 NC_010677.1 386781 387254 R frameshift compared to novicida makes this ORF 15 aa shorter; hypothetical protein complement(386781..387254) Francisella tularensis subsp. mediasiatica FSC147 6290769 YP_001891177.1 CDS FTM_0355 NC_010677.1 392469 393158 R two component response regulator complement(392469..393158) Francisella tularensis subsp. mediasiatica FSC147 6290450 YP_001891178.1 CDS FTM_0356 NC_010677.1 393301 393840 D membrane protein 393301..393840 Francisella tularensis subsp. mediasiatica FSC147 6290941 YP_001891179.1 CDS FTM_0357 NC_010677.1 393958 394359 D membrane protein 393958..394359 Francisella tularensis subsp. mediasiatica FSC147 6290403 YP_001891180.1 CDS FTM_0358 NC_010677.1 394534 395142 D lipoprotein 394534..395142 Francisella tularensis subsp. mediasiatica FSC147 6290284 YP_001891181.1 CDS FTM_0359 NC_010677.1 395199 396629 D hypothetical protein 395199..396629 Francisella tularensis subsp. mediasiatica FSC147 6291193 YP_001891182.1 CDS FTM_0360 NC_010677.1 396640 397623 D hypothetical protein 396640..397623 Francisella tularensis subsp. mediasiatica FSC147 6291554 YP_001891183.1 CDS FTM_0361 NC_010677.1 397629 399023 D lipoprotein 397629..399023 Francisella tularensis subsp. mediasiatica FSC147 6291573 YP_001891184.1 CDS FTM_0362 NC_010677.1 399163 400077 D hypothetical protein 399163..400077 Francisella tularensis subsp. mediasiatica FSC147 6290647 YP_001891185.1 CDS FTM_0364 NC_010677.1 401409 402824 D putative nicotinate phosphoribosyltransferase 401409..402824 Francisella tularensis subsp. mediasiatica FSC147 6290696 YP_001891186.1 CDS FTM_0366 NC_010677.1 404402 404890 R thioesterase family protein complement(404402..404890) Francisella tularensis subsp. mediasiatica FSC147 6290904 YP_001891187.1 CDS fadA NC_010677.1 404952 406139 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase complement(404952..406139) Francisella tularensis subsp. mediasiatica FSC147 6290562 YP_001891188.1 CDS FTM_0368 NC_010677.1 406152 408848 R bifunctional 3-hydroxacyl-CoA dehydrogenase/acyl-CoA-binding protein complement(406152..408848) Francisella tularensis subsp. mediasiatica FSC147 6290346 YP_001891189.1 CDS fadE NC_010677.1 408921 411161 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(408921..411161) Francisella tularensis subsp. mediasiatica FSC147 6290767 YP_001891190.1 CDS fadD NC_010677.1 411199 412887 R long chain fatty acid-CoA ligase complement(411199..412887) Francisella tularensis subsp. mediasiatica FSC147 6290653 YP_001891191.1 CDS FTM_0371 NC_010677.1 413031 413450 D arsenate reductase 413031..413450 Francisella tularensis subsp. mediasiatica FSC147 6290855 YP_001891192.1 CDS icd NC_010677.1 413499 415715 D isocitrate dehydrogenase 413499..415715 Francisella tularensis subsp. mediasiatica FSC147 6291670 YP_001891193.1 CDS FTM_0373 NC_010677.1 415729 416616 D membrane protein 415729..416616 Francisella tularensis subsp. mediasiatica FSC147 6291196 YP_001891194.1 CDS hrpA NC_010677.1 416640 420908 D ATP-dependent helicase HrpA 416640..420908 Francisella tularensis subsp. mediasiatica FSC147 6291347 YP_001891195.1 CDS FTM_0375 NC_010677.1 422409 423092 D hypothetical protein 422409..423092 Francisella tularensis subsp. mediasiatica FSC147 6290342 YP_001891196.1 CDS FTM_0379 NC_010677.1 426155 426727 R methylated DNA protein cysteine methyltransferase complement(426155..426727) Francisella tularensis subsp. mediasiatica FSC147 6291280 YP_001891197.1 CDS FTM_0380 NC_010677.1 426757 427476 D hypothetical protein 426757..427476 Francisella tularensis subsp. mediasiatica FSC147 6290148 YP_001891198.1 CDS FTM_0381 NC_010677.1 427479 428897 D dihydrolipoamide dehydrogenase 427479..428897 Francisella tularensis subsp. mediasiatica FSC147 6290333 YP_001891199.1 CDS FTM_0382 NC_010677.1 428894 429439 D phosphatidyltransferase 428894..429439 Francisella tularensis subsp. mediasiatica FSC147 6290859 YP_001891200.1 CDS FTM_0385 NC_010677.1 430639 431565 D subunit of DnaJ/DnaK/GrpE 430639..431565 Francisella tularensis subsp. mediasiatica FSC147 6290409 YP_001891201.1 CDS FTM_0386 NC_010677.1 431555 432439 R drug/metabolite exporter protein complement(431555..432439) Francisella tularensis subsp. mediasiatica FSC147 6290793 YP_001891202.1 CDS FTM_0388 NC_010677.1 433532 433888 D hypothetical protein 433532..433888 Francisella tularensis subsp. mediasiatica FSC147 6291564 YP_001891203.1 CDS relA NC_010677.1 434192 436201 D GDP pyrophosphokinase/GTP pyrophosphokinase 434192..436201 Francisella tularensis subsp. mediasiatica FSC147 6290404 YP_001891204.1 CDS FTM_0390 NC_010677.1 436317 436949 R hypothetical protein complement(436317..436949) Francisella tularensis subsp. mediasiatica FSC147 6291451 YP_001891205.1 CDS FTM_0392 NC_010677.1 437695 438309 D membrane protein 437695..438309 Francisella tularensis subsp. mediasiatica FSC147 6290297 YP_001891206.1 CDS FTM_0393 NC_010677.1 438316 439041 R hypothetical protein complement(438316..439041) Francisella tularensis subsp. mediasiatica FSC147 6290328 YP_001891207.1 CDS xerC NC_010677.1 439041 439919 R site-specific recombinase complement(439041..439919) Francisella tularensis subsp. mediasiatica FSC147 6290968 YP_001891208.1 CDS FTM_0395 NC_010677.1 439929 441101 R hydroxy/aromatic amino acid permease (HAAAP) family protein complement(439929..441101) Francisella tularensis subsp. mediasiatica FSC147 6290225 YP_001891209.1 CDS secB2 NC_010677.1 442579 443022 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(442579..443022) Francisella tularensis subsp. mediasiatica FSC147 6290864 YP_001891210.1 CDS mutS NC_010677.1 443099 445633 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(443099..445633) Francisella tularensis subsp. mediasiatica FSC147 6290338 YP_001891211.1 CDS accA NC_010677.1 445800 446747 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 445800..446747 Francisella tularensis subsp. mediasiatica FSC147 6291064 YP_001891212.1 CDS FTM_0400 NC_010677.1 446767 447270 D pilus assembly protein 446767..447270 Francisella tularensis subsp. mediasiatica FSC147 6290343 YP_001891213.1 CDS FTM_0401 NC_010677.1 447251 448264 D pilus assembly protein 447251..448264 Francisella tularensis subsp. mediasiatica FSC147 6290469 YP_001891214.1 CDS FTM_0402 NC_010677.1 448273 450237 D membrane protein 448273..450237 Francisella tularensis subsp. mediasiatica FSC147 6291703 YP_001891215.1 CDS murQ NC_010677.1 450234 451118 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 450234..451118 Francisella tularensis subsp. mediasiatica FSC147 6290852 YP_001891216.1 CDS FTM_0404 NC_010677.1 451120 451512 D hypothetical protein 451120..451512 Francisella tularensis subsp. mediasiatica FSC147 6290232 YP_001891217.1 CDS FTM_0406 NC_010677.1 454242 455540 R monovalent cation:proton antiporter-1 complement(454242..455540) Francisella tularensis subsp. mediasiatica FSC147 6290451 YP_001891218.1 CDS FTM_0407 NC_010677.1 455550 456275 R hypothetical protein complement(455550..456275) Francisella tularensis subsp. mediasiatica FSC147 6290722 YP_001891219.1 CDS trpS NC_010677.1 456277 457281 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(456277..457281) Francisella tularensis subsp. mediasiatica FSC147 6290655 YP_001891220.1 CDS coaE NC_010677.1 457578 458192 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(457578..458192) Francisella tularensis subsp. mediasiatica FSC147 6290511 YP_001891221.1 CDS FTM_0412 NC_010677.1 458321 459457 D hypothetical protein 458321..459457 Francisella tularensis subsp. mediasiatica FSC147 6291509 YP_001891222.1 CDS aceE NC_010677.1 459757 462438 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 459757..462438 Francisella tularensis subsp. mediasiatica FSC147 6290756 YP_001891223.1 CDS aceF NC_010677.1 462456 464039 D Deletion of 104 aa in FTM that is not present in SCHU; dihydrolipoamide acetyltransferase 462456..464039 Francisella tularensis subsp. mediasiatica FSC147 6290774 YP_001891224.1 CDS lpdA NC_010677.1 464053 465477 D pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase 464053..465477 Francisella tularensis subsp. mediasiatica FSC147 6290324 YP_001891225.1 CDS FTM_0416 NC_010677.1 466696 467343 D MutT/nudix family protein 466696..467343 Francisella tularensis subsp. mediasiatica FSC147 6291570 YP_001891226.1 CDS FTM_0417 NC_010677.1 467361 467714 D arsenate reductase 467361..467714 Francisella tularensis subsp. mediasiatica FSC147 6290682 YP_001891227.1 CDS FTM_0418 NC_010677.1 467738 468073 R lipoprotein complement(467738..468073) Francisella tularensis subsp. mediasiatica FSC147 6291449 YP_001891228.1 CDS FTM_0419 NC_010677.1 468573 469886 R permease complement(468573..469886) Francisella tularensis subsp. mediasiatica FSC147 6291603 YP_001891229.1 CDS FTM_0420 NC_010677.1 469953 471539 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(469953..471539) Francisella tularensis subsp. mediasiatica FSC147 6290364 YP_001891230.1 CDS FTM_0423 NC_010677.1 474447 475700 R OmpA family protein complement(474447..475700) Francisella tularensis subsp. mediasiatica FSC147 6291388 YP_001891231.1 CDS fkpB NC_010677.1 475892 476356 D fkbp-type 16 kda peptidyl-prolyl cis-transisomerase 475892..476356 Francisella tularensis subsp. mediasiatica FSC147 6290841 YP_001891232.1 CDS ispH NC_010677.1 476337 477293 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 476337..477293 Francisella tularensis subsp. mediasiatica FSC147 6291106 YP_001891233.1 CDS aroH NC_010677.1 477295 477657 D chorismate mutase 477295..477657 Francisella tularensis subsp. mediasiatica FSC147 6290839 YP_001891234.1 CDS pssA NC_010677.1 477666 478487 D phosphatidylserine synthase 477666..478487 Francisella tularensis subsp. mediasiatica FSC147 6290828 YP_001891235.1 CDS FTM_0428 NC_010677.1 478492 478716 R lipoprotein complement(478492..478716) Francisella tularensis subsp. mediasiatica FSC147 6290354 YP_001891236.1 CDS tolQ NC_010677.1 478869 479576 D group A colicin translocation protein TolQ 478869..479576 Francisella tularensis subsp. mediasiatica FSC147 6290489 YP_001891237.1 CDS tolR NC_010677.1 479592 480032 D group A colicin translocation protein TolR 479592..480032 Francisella tularensis subsp. mediasiatica FSC147 6290835 YP_001891238.1 CDS tolA NC_010677.1 480019 480906 D group A colicin translocation protein TolA 480019..480906 Francisella tularensis subsp. mediasiatica FSC147 6291545 YP_001891239.1 CDS tolB NC_010677.1 480918 482225 D group A colicin translocation protein TolB 480918..482225 Francisella tularensis subsp. mediasiatica FSC147 6290561 YP_001891240.1 CDS FTM_0433 NC_010677.1 482235 482480 D lipoprotein 482235..482480 Francisella tularensis subsp. mediasiatica FSC147 6290344 YP_001891241.1 CDS pal NC_010677.1 482499 483122 D peptidoglycan-associated lipoprotein 482499..483122 Francisella tularensis subsp. mediasiatica FSC147 6290997 YP_001891242.1 CDS FTM_0436 NC_010677.1 484653 485375 D short-chain dehydrogenase/reductase SDR 484653..485375 Francisella tularensis subsp. mediasiatica FSC147 6291661 YP_001891243.1 CDS FTM_0437 NC_010677.1 485438 485629 D hypothetical protein 485438..485629 Francisella tularensis subsp. mediasiatica FSC147 6290290 YP_001891244.1 CDS FTM_0438 NC_010677.1 485610 487109 D deoxyribodipyrimidine photolyase 485610..487109 Francisella tularensis subsp. mediasiatica FSC147 6290700 YP_001891245.1 CDS FTM_0440 NC_010677.1 488896 489825 D bile acid symporter family protein 488896..489825 Francisella tularensis subsp. mediasiatica FSC147 6291385 YP_001891246.1 CDS FTM_0442 NC_010677.1 490519 491277 D hypothetical protein 490519..491277 Francisella tularensis subsp. mediasiatica FSC147 6290442 YP_001891247.1 CDS FTM_0444 NC_010677.1 491814 492800 D hypothetical protein 491814..492800 Francisella tularensis subsp. mediasiatica FSC147 6290801 YP_001891248.1 CDS FTM_0445 NC_010677.1 493061 494209 D ORF shortened compared to SCHU and novicida. RBS site more suited to shorter version; arsenite permease family protein 493061..494209 Francisella tularensis subsp. mediasiatica FSC147 6291666 YP_001891249.1 CDS FTM_0446 NC_010677.1 494188 494610 R hypothetical protein complement(494188..494610) Francisella tularensis subsp. mediasiatica FSC147 6290431 YP_001891250.1 CDS FTM_0447 NC_010677.1 494630 494989 R hypothetical protein complement(494630..494989) Francisella tularensis subsp. mediasiatica FSC147 6291234 YP_001891251.1 CDS ubiA NC_010677.1 495003 495857 R UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase complement(495003..495857) Francisella tularensis subsp. mediasiatica FSC147 6290375 YP_001891252.1 CDS ubiC NC_010677.1 495860 496366 R chorismate pyruvate lyase complement(495860..496366) Francisella tularensis subsp. mediasiatica FSC147 6291532 YP_001891253.1 CDS rph NC_010677.1 496465 497172 D RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 496465..497172 Francisella tularensis subsp. mediasiatica FSC147 6290584 YP_001891254.1 CDS FTM_0451 NC_010677.1 497226 497549 R hypothetical protein complement(497226..497549) Francisella tularensis subsp. mediasiatica FSC147 6290306 YP_001891255.1 CDS htpX NC_010677.1 498666 499739 R putative metalloprotease; heat shock protein HtpX complement(498666..499739) Francisella tularensis subsp. mediasiatica FSC147 6291546 YP_001891256.1 CDS FTM_0454 NC_010677.1 499743 500318 R LemA-like protein complement(499743..500318) Francisella tularensis subsp. mediasiatica FSC147 6290889 YP_001891257.1 CDS FTM_0456 NC_010677.1 501402 502457 D hypothetical protein 501402..502457 Francisella tularensis subsp. mediasiatica FSC147 6290895 YP_001891258.1 CDS FTM_0458 NC_010677.1 503853 504218 R ArsR family transcriptional regulator complement(503853..504218) Francisella tularensis subsp. mediasiatica FSC147 6290907 YP_001891259.1 CDS gpsA NC_010677.1 505334 506332 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 505334..506332 Francisella tularensis subsp. mediasiatica FSC147 6290911 YP_001891260.1 CDS FTM_0461 NC_010677.1 506333 506869 R hypothetical protein complement(506333..506869) Francisella tularensis subsp. mediasiatica FSC147 6290916 YP_001891261.1 CDS radA NC_010677.1 506874 508244 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(506874..508244) Francisella tularensis subsp. mediasiatica FSC147 6290920 YP_001891262.1 CDS FTM_0463 NC_010677.1 508252 509022 R hypothetical protein complement(508252..509022) Francisella tularensis subsp. mediasiatica FSC147 6290928 YP_001891263.1 CDS FTM_0464 NC_010677.1 509019 509618 R membrane protein complement(509019..509618) Francisella tularensis subsp. mediasiatica FSC147 6290936 YP_001891264.1 CDS aroC NC_010677.1 509621 510679 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(509621..510679) Francisella tularensis subsp. mediasiatica FSC147 6290940 YP_001891265.1 CDS FTM_0466 NC_010677.1 510819 511472 R membrane protein complement(510819..511472) Francisella tularensis subsp. mediasiatica FSC147 6290944 YP_001891266.1 CDS FTM_0467 NC_010677.1 511487 511999 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(511487..511999) Francisella tularensis subsp. mediasiatica FSC147 6290946 YP_001891267.1 CDS sodC NC_010677.1 512160 512717 D copper/zinc superoxide dismutase 512160..512717 Francisella tularensis subsp. mediasiatica FSC147 6290948 YP_001891268.1 CDS FTM_0469 NC_010677.1 512721 513512 D sterol desaturase 512721..513512 Francisella tularensis subsp. mediasiatica FSC147 6290949 YP_001891269.1 CDS FTM_0470 NC_010677.1 513487 514881 R amino acid transporter (AAT) family protein complement(513487..514881) Francisella tularensis subsp. mediasiatica FSC147 6290953 YP_001891270.1 CDS FTM_0472 NC_010677.1 515486 516598 D Zn-dependent alcohol dehydrogenase 515486..516598 Francisella tularensis subsp. mediasiatica FSC147 6290963 YP_001891271.1 CDS FTM_0473 NC_010677.1 516647 517837 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(516647..517837) Francisella tularensis subsp. mediasiatica FSC147 6290970 YP_001891272.1 CDS FTM_0474 NC_010677.1 518040 518927 D cation diffusion facilitator (CDF) family protein 518040..518927 Francisella tularensis subsp. mediasiatica FSC147 6290975 YP_001891273.1 CDS recN NC_010677.1 519013 520662 D DNA repair protein RecN 519013..520662 Francisella tularensis subsp. mediasiatica FSC147 6290990 YP_001891274.1 CDS FTM_0477 NC_010677.1 522866 523306 R Type IV pili, pilus assembly protein complement(522866..523306) Francisella tularensis subsp. mediasiatica FSC147 6291003 YP_001891275.1 CDS pilA NC_010677.1 523437 523844 R Type IV pili, pilus assembly protein complement(523437..523844) Francisella tularensis subsp. mediasiatica FSC147 6291004 YP_001891276.1 CDS lpxE NC_010677.1 524226 524945 D lipid A 1-phosphatase 524226..524945 Francisella tularensis subsp. mediasiatica FSC147 6291007 YP_001891277.1 CDS folD NC_010677.1 525084 525932 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 525084..525932 Francisella tularensis subsp. mediasiatica FSC147 6291009 YP_001891278.1 CDS purM NC_010677.1 526166 527209 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 526166..527209 Francisella tularensis subsp. mediasiatica FSC147 6291012 YP_001891279.1 CDS FTM_0482 NC_010677.1 527209 529521 D saicar synthetase/phosphoribosylamine-glycine ligase 527209..529521 Francisella tularensis subsp. mediasiatica FSC147 6291017 YP_001891280.1 CDS purN NC_010677.1 529525 530100 D phosphoribosylglycinamide formyltransferase 529525..530100 Francisella tularensis subsp. mediasiatica FSC147 6291031 YP_001891281.1 CDS purE NC_010677.1 530217 530708 D N5-carboxyaminoimidazole ribonucleotide mutase 530217..530708 Francisella tularensis subsp. mediasiatica FSC147 6291034 YP_001891282.1 CDS purK NC_010677.1 530712 531809 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 530712..531809 Francisella tularensis subsp. mediasiatica FSC147 6291045 YP_001891283.1 CDS FTM_0486 NC_010677.1 531806 532159 R hypothetical protein complement(531806..532159) Francisella tularensis subsp. mediasiatica FSC147 6291049 YP_001891284.1 CDS prlC NC_010677.1 532226 534247 R oligopeptidase A complement(532226..534247) Francisella tularensis subsp. mediasiatica FSC147 6291051 YP_001891285.1 CDS FTM_0488 NC_010677.1 534339 534710 D membrane protein 534339..534710 Francisella tularensis subsp. mediasiatica FSC147 6291058 YP_001891286.1 CDS FTM_0489 NC_010677.1 534786 535235 D hypothetical protein 534786..535235 Francisella tularensis subsp. mediasiatica FSC147 6291060 YP_001891287.1 CDS FTM_0490 NC_010677.1 535392 535871 D lipoprotein 535392..535871 Francisella tularensis subsp. mediasiatica FSC147 6291062 YP_001891288.1 CDS FTM_0492 NC_010677.1 536507 536974 D hypothetical protein 536507..536974 Francisella tularensis subsp. mediasiatica FSC147 6291071 YP_001891289.1 CDS FTM_0493 NC_010677.1 537047 538489 D hypothetical protein 537047..538489 Francisella tularensis subsp. mediasiatica FSC147 6291077 YP_001891290.1 CDS topA NC_010677.1 538543 540837 R catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity; DNA topoisomerase I complement(538543..540837) Francisella tularensis subsp. mediasiatica FSC147 6291079 YP_001891291.1 CDS parA NC_010677.1 541036 541677 D chmomosome partition protein A 541036..541677 Francisella tularensis subsp. mediasiatica FSC147 6291092 YP_001891292.1 CDS parB NC_010677.1 541670 542584 D chromosome partition protein B 541670..542584 Francisella tularensis subsp. mediasiatica FSC147 6291098 YP_001891293.1 CDS FTM_0497 NC_010677.1 542598 543305 D glutamine amidotransferase 542598..543305 Francisella tularensis subsp. mediasiatica FSC147 6291108 YP_001891294.1 CDS FTM_0498 NC_010677.1 543308 544189 D lipolytic protein 543308..544189 Francisella tularensis subsp. mediasiatica FSC147 6291119 YP_001891295.1 CDS rrmJ NC_010677.1 544835 545455 R 23S rRNA methylase complement(544835..545455) Francisella tularensis subsp. mediasiatica FSC147 6291126 YP_001891296.1 CDS FTM_0501 NC_010677.1 545613 546080 D hypothetical protein 545613..546080 Francisella tularensis subsp. mediasiatica FSC147 6291139 YP_001891297.1 CDS lspA NC_010677.1 546075 546560 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(546075..546560) Francisella tularensis subsp. mediasiatica FSC147 6291152 YP_001891298.1 CDS ileS NC_010677.1 546547 549354 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(546547..549354) Francisella tularensis subsp. mediasiatica FSC147 6291158 YP_001891299.1 CDS ribF NC_010677.1 549447 550367 R riboflavin kinase/FMN adenylyltransferase complement(549447..550367) Francisella tularensis subsp. mediasiatica FSC147 6291162 YP_001891300.1 CDS maeA NC_010677.1 550518 552332 D malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 550518..552332 Francisella tularensis subsp. mediasiatica FSC147 6291163 YP_001891301.1 CDS FTM_0506 NC_010677.1 552495 554168 D lipoprotein 552495..554168 Francisella tularensis subsp. mediasiatica FSC147 6291166 YP_001891302.1 CDS FTM_0507 NC_010677.1 554185 555630 D hypothetical protein 554185..555630 Francisella tularensis subsp. mediasiatica FSC147 6291169 YP_001891303.1 CDS FTM_0509 NC_010677.1 557523 558041 D hypothetical protein 557523..558041 Francisella tularensis subsp. mediasiatica FSC147 6291179 YP_001891304.1 CDS engA NC_010677.1 558258 559655 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 558258..559655 Francisella tularensis subsp. mediasiatica FSC147 6291184 YP_001891305.1 CDS murA NC_010677.1 559624 560928 D UDP-N-acetylglucosamine enolpyruvoyl transferase 559624..560928 Francisella tularensis subsp. mediasiatica FSC147 6291188 YP_001891306.1 CDS murB NC_010677.1 560936 561784 D UDP-N-acetylmuramate dehydrogenase 560936..561784 Francisella tularensis subsp. mediasiatica FSC147 6291190 YP_001891307.1 CDS FTM_0513 NC_010677.1 561863 562738 D hypothetical protein 561863..562738 Francisella tularensis subsp. mediasiatica FSC147 6291195 YP_001891308.1 CDS FTM_0514 NC_010677.1 562740 563516 R hypothetical protein complement(562740..563516) Francisella tularensis subsp. mediasiatica FSC147 6291197 YP_001891309.1 CDS hitA NC_010677.1 564707 565045 R histidine triad (HIT) family protein complement(564707..565045) Francisella tularensis subsp. mediasiatica FSC147 6291203 YP_001891310.1 CDS ubiB NC_010677.1 565051 566709 R 2-octaprenylphenol hydroxylase complement(565051..566709) Francisella tularensis subsp. mediasiatica FSC147 6291205 YP_001891311.1 CDS FTM_0518 NC_010677.1 566702 567289 R hypothetical protein complement(566702..567289) Francisella tularensis subsp. mediasiatica FSC147 6291209 YP_001891312.1 CDS ubiE NC_010677.1 567291 568043 R ubiquinone/menaquinone biosynthesis methyltransferase UbiE complement(567291..568043) Francisella tularensis subsp. mediasiatica FSC147 6291216 YP_001891313.1 CDS glk NC_010677.1 568137 569153 D glucokinase 568137..569153 Francisella tularensis subsp. mediasiatica FSC147 6291218 YP_001891314.1 CDS ispZ NC_010677.1 569467 569997 R intracellular septation protein A family protein complement(569467..569997) Francisella tularensis subsp. mediasiatica FSC147 6291637 YP_001891315.1 CDS FTM_0522 NC_010677.1 570058 570672 D Sua5/YciO/YrdC family protein 570058..570672 Francisella tularensis subsp. mediasiatica FSC147 6291222 YP_001891316.1 CDS FTM_0523 NC_010677.1 570722 571324 D hypothetical protein 570722..571324 Francisella tularensis subsp. mediasiatica FSC147 6291224 YP_001891317.1 CDS FTM_0524 NC_010677.1 571321 572544 R major facilitator superfamily protein complement(571321..572544) Francisella tularensis subsp. mediasiatica FSC147 6291226 YP_001891318.1 CDS FTM_0529 NC_010677.1 575575 575832 R hypothetical protein complement(575575..575832) Francisella tularensis subsp. mediasiatica FSC147 6291275 YP_001891319.1 CDS FTM_0536 NC_010677.1 582489 583544 R hypothetical protein complement(582489..583544) Francisella tularensis subsp. mediasiatica FSC147 6291346 YP_001891320.1 CDS FTM_0537 NC_010677.1 583677 584333 R metallopeptidase complement(583677..584333) Francisella tularensis subsp. mediasiatica FSC147 6291358 YP_001891321.1 CDS FTM_0538 NC_010677.1 586480 586815 D hypothetical protein 586480..586815 Francisella tularensis subsp. mediasiatica FSC147 6291363 YP_001891322.1 CDS psd NC_010677.1 586788 587639 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(586788..587639) Francisella tularensis subsp. mediasiatica FSC147 6291369 YP_001891323.1 CDS FTM_0540 NC_010677.1 587739 588719 D hypothetical protein 587739..588719 Francisella tularensis subsp. mediasiatica FSC147 6291378 YP_001891324.1 CDS FTM_0541 NC_010677.1 588728 589771 D NadM-Nudix subfamily; involved in creation of nicotanimide adenine dinucleotide NAD from either biosynthetic or salvage pathways; bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase 588728..589771 Francisella tularensis subsp. mediasiatica FSC147 6291380 YP_001891325.1 CDS glmU NC_010677.1 589785 591152 D UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase 589785..591152 Francisella tularensis subsp. mediasiatica FSC147 6291389 YP_001891326.1 CDS glmS NC_010677.1 591173 593011 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 591173..593011 Francisella tularensis subsp. mediasiatica FSC147 6291402 YP_001891327.1 CDS rpsU NC_010677.1 593612 593809 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(593612..593809) Francisella tularensis subsp. mediasiatica FSC147 6291406 YP_001891328.1 CDS cspC NC_010677.1 593809 594012 R cold shock protein, DNA-binding complement(593809..594012) Francisella tularensis subsp. mediasiatica FSC147 6291421 YP_001891329.1 CDS FTM_0547 NC_010677.1 594261 594590 R hypothetical protein complement(594261..594590) Francisella tularensis subsp. mediasiatica FSC147 6291425 YP_001891330.1 CDS map NC_010677.1 594717 595487 D methionine aminopeptidase 594717..595487 Francisella tularensis subsp. mediasiatica FSC147 6291453 YP_001891331.1 CDS FTM_0549 NC_010677.1 595489 596337 D hypothetical protein 595489..596337 Francisella tularensis subsp. mediasiatica FSC147 6291455 YP_001891332.1 CDS parC NC_010677.1 597224 599449 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 597224..599449 Francisella tularensis subsp. mediasiatica FSC147 6291465 YP_001891333.1 CDS mtn NC_010677.1 599449 600135 D enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 599449..600135 Francisella tularensis subsp. mediasiatica FSC147 6291469 YP_001891334.1 CDS FTM_0553 NC_010677.1 600122 600721 R membrane protein complement(600122..600721) Francisella tularensis subsp. mediasiatica FSC147 6291472 YP_001891335.1 CDS FTM_0554 NC_010677.1 600714 601832 R BNR/Asp-box repeat-containing protein complement(600714..601832) Francisella tularensis subsp. mediasiatica FSC147 6291477 YP_001891336.1 CDS slt NC_010677.1 602031 604007 D soluble lytic murein transglycosylase 602031..604007 Francisella tularensis subsp. mediasiatica FSC147 6291508 YP_001891337.1 CDS FTM_0556 NC_010677.1 604021 604656 R hypothetical protein complement(604021..604656) Francisella tularensis subsp. mediasiatica FSC147 6291522 YP_001891338.1 CDS FTM_0557 NC_010677.1 605009 606163 D membrane protein 605009..606163 Francisella tularensis subsp. mediasiatica FSC147 6291529 YP_001891339.1 CDS FTM_0558 NC_010677.1 606520 609999 D DNA polymerase III subunit alpha 606520..609999 Francisella tularensis subsp. mediasiatica FSC147 6291531 YP_001891340.1 CDS FTM_0560 NC_010677.1 611388 612650 D ABC transporter involved in lipoprotein release, permease component 611388..612650 Francisella tularensis subsp. mediasiatica FSC147 6291560 YP_001891341.1 CDS FTM_0561 NC_010677.1 612643 613338 D ABC transporter ATPase 612643..613338 Francisella tularensis subsp. mediasiatica FSC147 6291599 YP_001891342.1 CDS gcvT NC_010677.1 615688 616764 D catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 615688..616764 Francisella tularensis subsp. mediasiatica FSC147 6291614 YP_001891343.1 CDS gcvH NC_010677.1 616821 617204 D glycine cleavage system H protein 616821..617204 Francisella tularensis subsp. mediasiatica FSC147 6291643 YP_001891344.1 CDS gcvP1 NC_010677.1 617269 618636 D acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 617269..618636 Francisella tularensis subsp. mediasiatica FSC147 6291653 YP_001891345.1 CDS gcvP2 NC_010677.1 618642 620087 D acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 618642..620087 Francisella tularensis subsp. mediasiatica FSC147 6291659 YP_001891346.1 CDS FTM_0567 NC_010677.1 620207 621052 R shikimate 5-dehydrogenase complement(620207..621052) Francisella tularensis subsp. mediasiatica FSC147 6291663 YP_001891347.1 CDS glgX NC_010677.1 621078 624290 R pullulanase complement(621078..624290) Francisella tularensis subsp. mediasiatica FSC147 6291665 YP_001891348.1 CDS glgB NC_010677.1 624324 626246 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein complement(624324..626246) Francisella tularensis subsp. mediasiatica FSC147 6291669 YP_001891349.1 CDS pgm NC_010677.1 626548 628182 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 626548..628182 Francisella tularensis subsp. mediasiatica FSC147 6291672 YP_001891350.1 CDS glgC NC_010677.1 628216 629487 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 628216..629487 Francisella tularensis subsp. mediasiatica FSC147 6291673 YP_001891351.1 CDS glgA NC_010677.1 629497 630966 D catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 629497..630966 Francisella tularensis subsp. mediasiatica FSC147 6291674 YP_001891352.1 CDS glgP NC_010677.1 631071 633344 D glycogen phosphorylase 631071..633344 Francisella tularensis subsp. mediasiatica FSC147 6291675 YP_001891353.1 CDS malQ NC_010677.1 633388 634851 D amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 633388..634851 Francisella tularensis subsp. mediasiatica FSC147 6291677 YP_001891354.1 CDS glyQ NC_010677.1 634943 635833 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 634943..635833 Francisella tularensis subsp. mediasiatica FSC147 6291681 YP_001891355.1 CDS murE NC_010677.1 636044 637483 D UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 636044..637483 Francisella tularensis subsp. mediasiatica FSC147 6291682 YP_001891356.1 CDS FTM_0577 NC_010677.1 637563 637922 D outer membrane lipoprotein 637563..637922 Francisella tularensis subsp. mediasiatica FSC147 6291683 YP_001891357.1 CDS murF NC_010677.1 638274 639632 D d-alanyl-d-alanine-adding enzyme 638274..639632 Francisella tularensis subsp. mediasiatica FSC147 6291684 YP_001891358.1 CDS FTM_0579 NC_010677.1 639641 640459 D hypothetical protein 639641..640459 Francisella tularensis subsp. mediasiatica FSC147 6291685 YP_001891359.1 CDS thrA NC_010677.1 641682 644102 D aspartate kinase I/homoserine dehydrogenase I 641682..644102 Francisella tularensis subsp. mediasiatica FSC147 6291690 YP_001891360.1 CDS thrB NC_010677.1 644105 645058 D homoserine kinase 644105..645058 Francisella tularensis subsp. mediasiatica FSC147 6291691 YP_001891361.1 CDS FTM_0585 NC_010677.1 646942 647430 D S-adenosylmethionine decarboxylase 646942..647430 Francisella tularensis subsp. mediasiatica FSC147 6291699 YP_001891362.1 CDS FTM_0586 NC_010677.1 647430 648299 D catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 647430..648299 Francisella tularensis subsp. mediasiatica FSC147 6291702 YP_001891363.1 CDS FTM_0587 NC_010677.1 648325 649734 D putative arginine decarboxylase 648325..649734 Francisella tularensis subsp. mediasiatica FSC147 6291705 YP_001891364.1 CDS FTM_0589 NC_010677.1 650944 651804 D hydrolase, carbon-nitrogen family 650944..651804 Francisella tularensis subsp. mediasiatica FSC147 6291711 YP_001891365.1 CDS lpxH NC_010677.1 651821 652537 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(651821..652537) Francisella tularensis subsp. mediasiatica FSC147 6291713 YP_001891366.1 CDS pyrE NC_010677.1 652527 653153 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(652527..653153) Francisella tularensis subsp. mediasiatica FSC147 6291714 YP_001891367.1 CDS mpl NC_010677.1 653313 654683 D UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 653313..654683 Francisella tularensis subsp. mediasiatica FSC147 6291715 YP_001891368.1 CDS FTM_0594 NC_010677.1 656238 656537 D ArsR family transcriptional regulator 656238..656537 Francisella tularensis subsp. mediasiatica FSC147 6290668 YP_001891369.1 CDS FTM_0597 NC_010677.1 658880 659566 D Zn-dependent hydrolase 658880..659566 Francisella tularensis subsp. mediasiatica FSC147 6291572 YP_001891370.1 CDS FTM_0599 NC_010677.1 660309 660929 R oxidoreductase complement(660309..660929) Francisella tularensis subsp. mediasiatica FSC147 6291481 YP_001891371.1 CDS FTM_0600 NC_010677.1 660969 661418 R hypothetical protein complement(660969..661418) Francisella tularensis subsp. mediasiatica FSC147 6291647 YP_001891372.1 CDS FTM_0602 NC_010677.1 662165 662566 R hypothetical protein complement(662165..662566) Francisella tularensis subsp. mediasiatica FSC147 6291595 YP_001891373.1 CDS nusB NC_010677.1 662753 663178 D transcription antitermination factor NusB 662753..663178 Francisella tularensis subsp. mediasiatica FSC147 6291627 YP_001891374.1 CDS FTM_0604 NC_010677.1 663162 663932 R carbon-nitrogen hydrolase complement(663162..663932) Francisella tularensis subsp. mediasiatica FSC147 6291538 YP_001891375.1 CDS FTM_0605 NC_010677.1 664101 664514 D lipoprotein 664101..664514 Francisella tularensis subsp. mediasiatica FSC147 6291525 YP_001891376.1 CDS FTM_0607 NC_010677.1 666059 667192 R aspartate/tyrosine/aromatic aminotransferase complement(666059..667192) Francisella tularensis subsp. mediasiatica FSC147 6291503 YP_001891377.1 CDS proS NC_010677.1 667338 669035 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(667338..669035) Francisella tularensis subsp. mediasiatica FSC147 6291487 YP_001891378.1 CDS FTM_0609 NC_010677.1 671064 671291 R hypothetical protein complement(671064..671291) Francisella tularensis subsp. mediasiatica FSC147 6291494 YP_001891379.1 CDS FTM_0610 NC_010677.1 671623 672159 R disulfide bond formation protein, DsbB family complement(671623..672159) Francisella tularensis subsp. mediasiatica FSC147 6291479 YP_001891380.1 CDS sufE NC_010677.1 672866 673282 D sulfur acceptor protein SufE 672866..673282 Francisella tularensis subsp. mediasiatica FSC147 6291471 YP_001891381.1 CDS FTM_0613 NC_010677.1 673283 674032 D uroporphyrinogen III synthase 673283..674032 Francisella tularensis subsp. mediasiatica FSC147 6291473 YP_001891382.1 CDS FTM_0614 NC_010677.1 673998 675083 D membrane protein 673998..675083 Francisella tularensis subsp. mediasiatica FSC147 6291442 YP_001891383.1 CDS FTM_0615 NC_010677.1 675080 676237 D membrane protein 675080..676237 Francisella tularensis subsp. mediasiatica FSC147 6291446 YP_001891384.1 CDS gloB NC_010677.1 676251 677009 D hydroxyacylglutathione hydrolase 676251..677009 Francisella tularensis subsp. mediasiatica FSC147 6291422 YP_001891385.1 CDS FTM_0617 NC_010677.1 677087 677794 R hypothetical protein complement(677087..677794) Francisella tularensis subsp. mediasiatica FSC147 6291434 YP_001891386.1 CDS feoA NC_010677.1 677903 678127 D Fe2+ transport system protein A 677903..678127 Francisella tularensis subsp. mediasiatica FSC147 6291401 YP_001891387.1 CDS FTM_0619 NC_010677.1 678144 679778 D hypothetical protein 678144..679778 Francisella tularensis subsp. mediasiatica FSC147 6291403 YP_001891388.1 CDS FTM_0623 NC_010677.1 680350 681003 R prophage repressor protein complement(680350..681003) Francisella tularensis subsp. mediasiatica FSC147 6291356 YP_001891389.1 CDS FTM_0624 NC_010677.1 681172 681558 D hypothetical protein 681172..681558 Francisella tularensis subsp. mediasiatica FSC147 6291322 YP_001891390.1 CDS FTM_0625 NC_010677.1 681572 682441 R drug/metabolite exporter complement(681572..682441) Francisella tularensis subsp. mediasiatica FSC147 6291335 YP_001891391.1 CDS gltB NC_010677.1 682618 684204 D glutamate synthase domain 2 682618..684204 Francisella tularensis subsp. mediasiatica FSC147 6291295 YP_001891392.1 CDS recC NC_010677.1 684281 687520 D exodeoxyribonuclease V subunit gamma 684281..687520 Francisella tularensis subsp. mediasiatica FSC147 6291297 YP_001891393.1 CDS FTM_0628 NC_010677.1 687462 688034 D hypothetical protein 687462..688034 Francisella tularensis subsp. mediasiatica FSC147 6291263 YP_001891394.1 CDS FTM_0629 NC_010677.1 688177 689565 D ATP-dependent DNA helicase 688177..689565 Francisella tularensis subsp. mediasiatica FSC147 6291712 YP_001891395.1 CDS recB NC_010677.1 689637 693290 D exodeoxyribonuclease V subunit beta 689637..693290 Francisella tularensis subsp. mediasiatica FSC147 6291707 YP_001891396.1 CDS recD NC_010677.1 693256 695124 D exodeoxyribonuclease V subunit alpha 693256..695124 Francisella tularensis subsp. mediasiatica FSC147 6290108 YP_001891397.1 CDS FTM_0632 NC_010677.1 695133 695903 R type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase complement(695133..695903) Francisella tularensis subsp. mediasiatica FSC147 6291244 YP_001891398.1 CDS panD NC_010677.1 695907 696242 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(695907..696242) Francisella tularensis subsp. mediasiatica FSC147 6291250 YP_001891399.1 CDS panC NC_010677.1 696236 697021 R pantoate-beta-alanine ligase complement(696236..697021) Francisella tularensis subsp. mediasiatica FSC147 6291213 YP_001891400.1 CDS panB NC_010677.1 697008 697805 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(697008..697805) Francisella tularensis subsp. mediasiatica FSC147 6291217 YP_001891401.1 CDS FTM_0636 NC_010677.1 697807 698523 R hypothetical protein complement(697807..698523) Francisella tularensis subsp. mediasiatica FSC147 6291208 YP_001891402.1 CDS ligA NC_010677.1 698831 700867 D NAD-dependent DNA ligase 698831..700867 Francisella tularensis subsp. mediasiatica FSC147 6291189 YP_001891403.1 CDS FTM_0639 NC_010677.1 702322 702813 D acetyltransferase 702322..702813 Francisella tularensis subsp. mediasiatica FSC147 6291020 YP_001891404.1 CDS sun NC_010677.1 702791 704071 R tRNA and rRNA cytosine-C5-methylase, sun protein complement(702791..704071) Francisella tularensis subsp. mediasiatica FSC147 6291185 YP_001891405.1 CDS FTM_0641 NC_010677.1 704071 704859 R inositol-1-monophosphatase complement(704071..704859) Francisella tularensis subsp. mediasiatica FSC147 6291164 YP_001891406.1 CDS FTM_0643 NC_010677.1 705884 707083 R hypothetical protein complement(705884..707083) Francisella tularensis subsp. mediasiatica FSC147 6291155 YP_001891407.1 CDS FTM_0644 NC_010677.1 707205 707891 D hypothetical protein 707205..707891 Francisella tularensis subsp. mediasiatica FSC147 6291159 YP_001891408.1 CDS FTM_0645 NC_010677.1 707881 708165 R hypothetical protein complement(707881..708165) Francisella tularensis subsp. mediasiatica FSC147 6291140 YP_001891409.1 CDS fabF NC_010677.1 708245 709504 R beta-ketoacyl-ACP synthase II complement(708245..709504) Francisella tularensis subsp. mediasiatica FSC147 6291150 YP_001891410.1 CDS acpP NC_010677.1 709584 709868 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(709584..709868) Francisella tularensis subsp. mediasiatica FSC147 6291101 YP_001891411.1 CDS fabG NC_010677.1 709964 710707 R beta-ketoacyl-ACP reductase complement(709964..710707) Francisella tularensis subsp. mediasiatica FSC147 6291093 YP_001891412.1 CDS fabD NC_010677.1 710721 711641 R malonyl-CoA:ACP transacylase complement(710721..711641) Francisella tularensis subsp. mediasiatica FSC147 6291078 YP_001891413.1 CDS fabH NC_010677.1 711689 712660 R 3-oxoacyl-ACP synthase complement(711689..712660) Francisella tularensis subsp. mediasiatica FSC147 6291059 YP_001891414.1 CDS plsX NC_010677.1 712757 713803 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX complement(712757..713803) Francisella tularensis subsp. mediasiatica FSC147 6291068 YP_001891415.1 CDS rpmF NC_010677.1 713902 714084 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(713902..714084) Francisella tularensis subsp. mediasiatica FSC147 6291048 YP_001891416.1 CDS FTM_0653 NC_010677.1 714128 714631 R hypothetical protein complement(714128..714631) Francisella tularensis subsp. mediasiatica FSC147 6291050 YP_001891417.1 CDS FTM_0654 NC_010677.1 714771 717800 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 714771..717800 Francisella tularensis subsp. mediasiatica FSC147 6291029 YP_001891418.1 CDS pgk NC_010677.1 717819 718997 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 717819..718997 Francisella tularensis subsp. mediasiatica FSC147 6291083 YP_001891419.1 CDS pyk NC_010677.1 719013 720449 D pyruvate kinase 719013..720449 Francisella tularensis subsp. mediasiatica FSC147 6291024 YP_001891420.1 CDS fbaA NC_010677.1 720465 721529 D class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 720465..721529 Francisella tularensis subsp. mediasiatica FSC147 6291033 YP_001891421.1 CDS potG NC_010677.1 724593 725714 D ATP-binding cassette putrescine uptake system, ATP-binding protein 724593..725714 Francisella tularensis subsp. mediasiatica FSC147 6291008 YP_001891422.1 CDS potH NC_010677.1 725714 726595 D ATP-binding cassette putrescine uptake system, membrane protein, subunit H 725714..726595 Francisella tularensis subsp. mediasiatica FSC147 6291010 YP_001891423.1 CDS potI NC_010677.1 726609 727415 D ATP-binding cassette putrescine uptake system, membrane protein, subunit I 726609..727415 Francisella tularensis subsp. mediasiatica FSC147 6290996 YP_001891424.1 CDS aroA NC_010677.1 728464 729741 D 3-phosphoshikimate 1-carboxyvinyltransferase 728464..729741 Francisella tularensis subsp. mediasiatica FSC147 6291006 YP_001891425.1 CDS FTM_0664 NC_010677.1 729744 730334 D hypothetical protein 729744..730334 Francisella tularensis subsp. mediasiatica FSC147 6290989 YP_001891426.1 CDS rnhA NC_010677.1 730309 730767 D Ribonuclease H 730309..730767 Francisella tularensis subsp. mediasiatica FSC147 6290991 YP_001891427.1 CDS ansA NC_010677.1 730769 731806 D L-asparaginase 1 730769..731806 Francisella tularensis subsp. mediasiatica FSC147 6290981 YP_001891428.1 CDS cynT NC_010677.1 731877 732563 D carbonic anhydrase 731877..732563 Francisella tularensis subsp. mediasiatica FSC147 6290956 YP_001891429.1 CDS FTM_0668 NC_010677.1 732850 733455 R membrane protein complement(732850..733455) Francisella tularensis subsp. mediasiatica FSC147 6291695 YP_001891430.1 CDS FTM_0669 NC_010677.1 733519 734391 R hypothetical protein complement(733519..734391) Francisella tularensis subsp. mediasiatica FSC147 6290958 YP_001891431.1 CDS rubA NC_010677.1 734400 734570 R rubredoxin complement(734400..734570) Francisella tularensis subsp. mediasiatica FSC147 6290951 YP_001891432.1 CDS FTM_0671 NC_010677.1 734657 735274 R hypothetical protein complement(734657..735274) Francisella tularensis subsp. mediasiatica FSC147 6290955 YP_001891433.1 CDS FTM_0672 NC_010677.1 735386 736777 D hypothetical protein 735386..736777 Francisella tularensis subsp. mediasiatica FSC147 6290939 YP_001891434.1 CDS FTM_0673 NC_010677.1 736809 738083 R dicarboxylate/amino acid:cation (Na+ or H+) symporter complement(736809..738083) Francisella tularensis subsp. mediasiatica FSC147 6290947 YP_001891435.1 CDS FTM_0674 NC_010677.1 738285 739313 D phosphosugar binding protein 738285..739313 Francisella tularensis subsp. mediasiatica FSC147 6290923 YP_001891436.1 CDS FTM_0675 NC_010677.1 739338 740741 D MFS family major facilitator transporter 739338..740741 Francisella tularensis subsp. mediasiatica FSC147 6290931 YP_001891437.1 CDS FTM_0676 NC_010677.1 740895 741014 D hypothetical protein 740895..741014 Francisella tularensis subsp. mediasiatica FSC147 6290919 YP_001891438.1 CDS FTM_0677 NC_010677.1 741128 741436 D IS1 transposase 741128..741436 Francisella tularensis subsp. mediasiatica FSC147 6290914 YP_001891439.1 CDS FTM_0679 NC_010677.1 743655 743834 D hypothetical protein 743655..743834 Francisella tularensis subsp. mediasiatica FSC147 6290891 YP_001891440.1 CDS ispG NC_010677.1 745851 747068 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 745851..747068 Francisella tularensis subsp. mediasiatica FSC147 6291147 YP_001891441.1 CDS FTM_0683 NC_010677.1 747083 747790 D hypothetical protein 747083..747790 Francisella tularensis subsp. mediasiatica FSC147 6291099 YP_001891442.1 CDS FTM_0684 NC_010677.1 747809 749602 D X-prolyl aminopeptidase 2 747809..749602 Francisella tularensis subsp. mediasiatica FSC147 6291326 YP_001891443.1 CDS FTM_0685 NC_010677.1 749700 750764 D DNA/RNA endonuclease G 749700..750764 Francisella tularensis subsp. mediasiatica FSC147 6291052 YP_001891444.1 CDS FTM_0686 NC_010677.1 750755 751618 R beta-lactamase class A complement(750755..751618) Francisella tularensis subsp. mediasiatica FSC147 6291689 YP_001891445.1 CDS FTM_0688 NC_010677.1 753187 753606 R hypothetical protein complement(753187..753606) Francisella tularensis subsp. mediasiatica FSC147 6291292 YP_001891446.1 CDS lnt NC_010677.1 753852 755342 R apolipoprotein N-acyltransferase complement(753852..755342) Francisella tularensis subsp. mediasiatica FSC147 6291704 YP_001891447.1 CDS FTM_0690 NC_010677.1 755342 756184 R transporter-associated protein, HlyC/CorC family complement(755342..756184) Francisella tularensis subsp. mediasiatica FSC147 6291448 YP_001891448.1 CDS FTM_0691 NC_010677.1 756174 756662 R hypothetical protein complement(756174..756662) Francisella tularensis subsp. mediasiatica FSC147 6290924 YP_001891449.1 CDS FTM_0692 NC_010677.1 756655 757638 R PhoH family protein ATPase complement(756655..757638) Francisella tularensis subsp. mediasiatica FSC147 6291002 YP_001891450.1 CDS miaB NC_010677.1 757642 758970 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(757642..758970) Francisella tularensis subsp. mediasiatica FSC147 6291686 YP_001891451.1 CDS FTM_0694 NC_010677.1 759193 759867 D O-methyltransferase family protein 759193..759867 Francisella tularensis subsp. mediasiatica FSC147 6291567 YP_001891452.1 CDS tdk NC_010677.1 760619 761212 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 760619..761212 Francisella tularensis subsp. mediasiatica FSC147 6291454 YP_001891453.1 CDS FTM_0697 NC_010677.1 761255 761719 R membrane protein complement(761255..761719) Francisella tularensis subsp. mediasiatica FSC147 6291620 YP_001891454.1 CDS tig NC_010677.1 761874 763190 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 761874..763190 Francisella tularensis subsp. mediasiatica FSC147 6291070 YP_001891455.1 CDS clpP NC_010677.1 763216 763821 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 763216..763821 Francisella tularensis subsp. mediasiatica FSC147 6291510 YP_001891456.1 CDS clpX NC_010677.1 763845 765098 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 763845..765098 Francisella tularensis subsp. mediasiatica FSC147 6291414 YP_001891457.1 CDS lon NC_010677.1 765123 767447 D ATP-dependent protease La 765123..767447 Francisella tularensis subsp. mediasiatica FSC147 6291571 YP_001891458.1 CDS hupB NC_010677.1 767534 767806 D DNA-binding protein HU-beta 767534..767806 Francisella tularensis subsp. mediasiatica FSC147 6291413 YP_001891459.1 CDS FTM_0703 NC_010677.1 767920 769353 D hypothetical protein 767920..769353 Francisella tularensis subsp. mediasiatica FSC147 6291575 YP_001891460.1 CDS miaA NC_010677.1 769354 770280 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 769354..770280 Francisella tularensis subsp. mediasiatica FSC147 6291710 YP_001891461.1 CDS hfq NC_010677.1 770391 770720 D host factor I for bacteriophage Q beta replication 770391..770720 Francisella tularensis subsp. mediasiatica FSC147 6291457 YP_001891462.1 CDS hflX NC_010677.1 770769 772079 D protease, GTP-binding subunit 770769..772079 Francisella tularensis subsp. mediasiatica FSC147 6291284 YP_001891463.1 CDS FTM_0707 NC_010677.1 772090 773268 R hypothetical protein complement(772090..773268) Francisella tularensis subsp. mediasiatica FSC147 6291552 YP_001891464.1 CDS hflK NC_010677.1 773453 774520 D HflK-HflC membrane protein complex, HflK 773453..774520 Francisella tularensis subsp. mediasiatica FSC147 6291521 YP_001891465.1 CDS hflC NC_010677.1 774522 775448 D HflK-HflC membrane protein complex, HflC 774522..775448 Francisella tularensis subsp. mediasiatica FSC147 6291679 YP_001891466.1 CDS wzb NC_010677.1 775449 775934 D low molecular weight (LMW) phosphotyrosine protein phosphatase 775449..775934 Francisella tularensis subsp. mediasiatica FSC147 6291452 YP_001891467.1 CDS engB NC_010677.1 775931 776524 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 775931..776524 Francisella tularensis subsp. mediasiatica FSC147 6289967 YP_001891468.1 CDS FTM_0712 NC_010677.1 777577 778773 R ATPase complement(777577..778773) Francisella tularensis subsp. mediasiatica FSC147 6289968 YP_001891469.1 CDS serA NC_010677.1 778774 780009 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(778774..780009) Francisella tularensis subsp. mediasiatica FSC147 6289969 YP_001891470.1 CDS thyA NC_010677.1 780021 780845 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(780021..780845) Francisella tularensis subsp. mediasiatica FSC147 6289970 YP_001891471.1 CDS lgt NC_010677.1 780830 781636 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(780830..781636) Francisella tularensis subsp. mediasiatica FSC147 6289972 YP_001891472.1 CDS rne NC_010677.1 781651 784308 R ribonuclease E complement(781651..784308) Francisella tularensis subsp. mediasiatica FSC147 6289973 YP_001891473.1 CDS iscS NC_010677.1 784558 785733 D cysteine desulfurase 784558..785733 Francisella tularensis subsp. mediasiatica FSC147 6289975 YP_001891474.1 CDS FTM_0718 NC_010677.1 785726 786055 D hypothetical protein 785726..786055 Francisella tularensis subsp. mediasiatica FSC147 6289976 YP_001891475.1 CDS recO NC_010677.1 786039 786737 D RecFOR complex, RecO component 786039..786737 Francisella tularensis subsp. mediasiatica FSC147 6289977 YP_001891476.1 CDS FTM_0720 NC_010677.1 786813 787460 R DedA family protein complement(786813..787460) Francisella tularensis subsp. mediasiatica FSC147 6289978 YP_001891477.1 CDS FTM_0721 NC_010677.1 787516 788142 R DedA family protein complement(787516..788142) Francisella tularensis subsp. mediasiatica FSC147 6289979 YP_001891478.1 CDS FTM_0722 NC_010677.1 788149 788415 R BolA family protein complement(788149..788415) Francisella tularensis subsp. mediasiatica FSC147 6289980 YP_001891479.1 CDS FTM_0723 NC_010677.1 788418 788966 R 5-formyltetrahydrofolate cyclo-ligase complement(788418..788966) Francisella tularensis subsp. mediasiatica FSC147 6289981 YP_001891480.1 CDS FTM_0724 NC_010677.1 789292 789942 D hypothetical protein 789292..789942 Francisella tularensis subsp. mediasiatica FSC147 6289982 YP_001891481.1 CDS ubiH NC_010677.1 789951 791162 D 2-octaprenyl-6-methoxyphenyl hydroxylase 789951..791162 Francisella tularensis subsp. mediasiatica FSC147 6289984 YP_001891482.1 CDS FTM_0726 NC_010677.1 791152 792387 D 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 791152..792387 Francisella tularensis subsp. mediasiatica FSC147 6289985 YP_001891483.1 CDS FTM_0727 NC_010677.1 792409 792870 D hypothetical protein 792409..792870 Francisella tularensis subsp. mediasiatica FSC147 6289987 YP_001891484.1 CDS queA NC_010677.1 792896 793912 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 792896..793912 Francisella tularensis subsp. mediasiatica FSC147 6289988 YP_001891485.1 CDS FTM_0729 NC_010677.1 794548 795339 D haloacid dehalogenase-like hydrolase 794548..795339 Francisella tularensis subsp. mediasiatica FSC147 6289990 YP_001891486.1 CDS FTM_0730 NC_010677.1 795593 796378 R hypothetical protein complement(795593..796378) Francisella tularensis subsp. mediasiatica FSC147 6289991 YP_001891487.1 CDS FTM_0733 NC_010677.1 798640 798828 D hypothetical protein 798640..798828 Francisella tularensis subsp. mediasiatica FSC147 6289994 YP_001891488.1 CDS kdsB NC_010677.1 798821 799573 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 798821..799573 Francisella tularensis subsp. mediasiatica FSC147 6289995 YP_001891489.1 CDS FTM_0735 NC_010677.1 799566 799961 D HIT family protein 799566..799961 Francisella tularensis subsp. mediasiatica FSC147 6289996 YP_001891490.1 CDS galK NC_010677.1 799958 801106 R galactokinase complement(799958..801106) Francisella tularensis subsp. mediasiatica FSC147 6289997 YP_001891491.1 CDS galT NC_010677.1 801109 802134 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(801109..802134) Francisella tularensis subsp. mediasiatica FSC147 6289999 YP_001891492.1 CDS galP1 NC_010677.1 802225 803607 D galactose-proton symporter 802225..803607 Francisella tularensis subsp. mediasiatica FSC147 6290000 YP_001891493.1 CDS galP2 NC_010677.1 803639 805033 D galactose-proton symporter 803639..805033 Francisella tularensis subsp. mediasiatica FSC147 6290003 YP_001891494.1 CDS ppiC NC_010677.1 805128 805406 D parvulin-like peptidyl-prolyl isomerase domain 805128..805406 Francisella tularensis subsp. mediasiatica FSC147 6290004 YP_001891495.1 CDS deaD NC_010677.1 805471 807180 D DEAD/DEAH box helicase 805471..807180 Francisella tularensis subsp. mediasiatica FSC147 6290005 YP_001891496.1 CDS gmk NC_010677.1 807297 807869 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 807297..807869 Francisella tularensis subsp. mediasiatica FSC147 6290006 YP_001891497.1 CDS nadA NC_010677.1 807890 808915 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 807890..808915 Francisella tularensis subsp. mediasiatica FSC147 6290008 YP_001891498.1 CDS nadC NC_010677.1 808924 809784 D nicotinate-nucleotide pyrophosphorylase 808924..809784 Francisella tularensis subsp. mediasiatica FSC147 6290010 YP_001891499.1 CDS nadB NC_010677.1 809787 811274 D L-aspartate oxidase 809787..811274 Francisella tularensis subsp. mediasiatica FSC147 6290011 YP_001891500.1 CDS FTM_0748 NC_010677.1 813968 814258 D hypothetical protein 813968..814258 Francisella tularensis subsp. mediasiatica FSC147 6290014 YP_001891501.1 CDS FTM_0749 NC_010677.1 814287 814757 D glutathione peroxidase 814287..814757 Francisella tularensis subsp. mediasiatica FSC147 6290015 YP_001891502.1 CDS FTM_0752 NC_010677.1 817045 817692 D hypothetical protein 817045..817692 Francisella tularensis subsp. mediasiatica FSC147 6290018 YP_001891503.1 CDS FTM_0753 NC_010677.1 817703 817831 R membrane protein complement(817703..817831) Francisella tularensis subsp. mediasiatica FSC147 6290020 YP_001891504.1 CDS FTM_0754 NC_010677.1 817999 819492 D carbohydrate kinase family protein 817999..819492 Francisella tularensis subsp. mediasiatica FSC147 6290022 YP_001891505.1 CDS FTM_0755 NC_010677.1 819527 819895 R heat shock protein 15 complement(819527..819895) Francisella tularensis subsp. mediasiatica FSC147 6290023 YP_001891506.1 CDS FTM_0758 NC_010677.1 825643 826458 D hypothetical protein 825643..826458 Francisella tularensis subsp. mediasiatica FSC147 6290027 YP_001891507.1 CDS FTM_0760 NC_010677.1 828252 829097 R auxiliary transport protein complement(828252..829097) Francisella tularensis subsp. mediasiatica FSC147 6290029 YP_001891508.1 CDS FTM_0761 NC_010677.1 829099 829302 R hypothetical protein complement(829099..829302) Francisella tularensis subsp. mediasiatica FSC147 6290030 YP_001891509.1 CDS FTM_0762 NC_010677.1 829499 830218 D transcriptional regulator, IclR family 829499..830218 Francisella tularensis subsp. mediasiatica FSC147 6290033 YP_001891510.1 CDS FTM_0764 NC_010677.1 831312 831428 R hypothetical protein complement(831312..831428) Francisella tularensis subsp. mediasiatica FSC147 6290035 YP_001891511.1 CDS FTM_0765 NC_010677.1 831467 832453 D aminomutase 831467..832453 Francisella tularensis subsp. mediasiatica FSC147 6290036 YP_001891512.1 CDS cspA NC_010677.1 832524 832727 R cold shock protein, DNA-binding complement(832524..832727) Francisella tularensis subsp. mediasiatica FSC147 6290041 YP_001891513.1 CDS FTM_0767 NC_010677.1 832926 833210 R hypothetical protein complement(832926..833210) Francisella tularensis subsp. mediasiatica FSC147 6290042 YP_001891514.1 CDS rpsU NC_010677.1 833500 833700 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 833500..833700 Francisella tularensis subsp. mediasiatica FSC147 6290043 YP_001891515.1 CDS FTM_0771 NC_010677.1 835219 836358 D Co/Zn/Cd cation transporter 835219..836358 Francisella tularensis subsp. mediasiatica FSC147 6290049 YP_001891516.1 CDS galU NC_010677.1 836375 837238 D UTP-glucose-1-phosphate uridylyltransferase 836375..837238 Francisella tularensis subsp. mediasiatica FSC147 6290050 YP_001891517.1 CDS FTM_0774 NC_010677.1 838711 839628 D integral membrane protein 838711..839628 Francisella tularensis subsp. mediasiatica FSC147 6290053 YP_001891518.1 CDS FTM_0775 NC_010677.1 839631 839837 R lipoprotein complement(839631..839837) Francisella tularensis subsp. mediasiatica FSC147 6290056 YP_001891519.1 CDS FTM_0776 NC_010677.1 839922 840215 R hypothetical protein complement(839922..840215) Francisella tularensis subsp. mediasiatica FSC147 6290059 YP_001891520.1 CDS recF NC_010677.1 840237 841286 R RecFOR complex, RecF component complement(840237..841286) Francisella tularensis subsp. mediasiatica FSC147 6290061 YP_001891521.1 CDS FTM_0778 NC_010677.1 841290 842036 R Mg-dependent DNase complement(841290..842036) Francisella tularensis subsp. mediasiatica FSC147 6290063 YP_001891522.1 CDS glyS NC_010677.1 842229 844313 D glycyl-tRNA synthetase subunit beta 842229..844313 Francisella tularensis subsp. mediasiatica FSC147 6290064 YP_001891523.1 CDS rpiA NC_010677.1 847186 847860 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(847186..847860) Francisella tularensis subsp. mediasiatica FSC147 6290067 YP_001891524.1 CDS FTM_0782 NC_010677.1 847862 849232 R membrane protein complement(847862..849232) Francisella tularensis subsp. mediasiatica FSC147 6290070 YP_001891525.1 CDS FTM_0783 NC_010677.1 849246 849638 R lipoprotein complement(849246..849638) Francisella tularensis subsp. mediasiatica FSC147 6290071 YP_001891526.1 CDS gidA NC_010677.1 849650 851533 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(849650..851533) Francisella tularensis subsp. mediasiatica FSC147 6290072 YP_001891527.1 CDS FTM_0785 NC_010677.1 851676 852758 D membrane protein 851676..852758 Francisella tularensis subsp. mediasiatica FSC147 6290074 YP_001891528.1 CDS FTM_0786 NC_010677.1 852745 853650 D membrane protein 852745..853650 Francisella tularensis subsp. mediasiatica FSC147 6290075 YP_001891529.1 CDS FTM_0787 NC_010677.1 853661 854560 R transcriptional regulator, LysR family complement(853661..854560) Francisella tularensis subsp. mediasiatica FSC147 6290077 YP_001891530.1 CDS FTM_0788 NC_010677.1 854676 855398 D oxidoreductase, short-chain dehydrogenase family protein 854676..855398 Francisella tularensis subsp. mediasiatica FSC147 6290078 YP_001891531.1 CDS sbcB NC_010677.1 855532 856980 D exodeoxyribonuclease I 855532..856980 Francisella tularensis subsp. mediasiatica FSC147 6290080 YP_001891532.1 CDS uvrB NC_010677.1 856982 858988 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 856982..858988 Francisella tularensis subsp. mediasiatica FSC147 6290083 YP_001891533.1 CDS FTM_0791 NC_010677.1 859025 859822 D membrane protein 859025..859822 Francisella tularensis subsp. mediasiatica FSC147 6290087 YP_001891534.1 CDS murI NC_010677.1 859822 860619 D glutamate racemase 859822..860619 Francisella tularensis subsp. mediasiatica FSC147 6290089 YP_001891535.1 CDS FTM_0793 NC_010677.1 860710 861987 D metabolite:H+ symporter (MHS) family protein 860710..861987 Francisella tularensis subsp. mediasiatica FSC147 6290092 YP_001891536.1 CDS FTM_0795 NC_010677.1 863660 864586 D hypothetical protein 863660..864586 Francisella tularensis subsp. mediasiatica FSC147 6290094 YP_001891537.1 CDS xseA NC_010677.1 867716 869101 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 867716..869101 Francisella tularensis subsp. mediasiatica FSC147 6290103 YP_001891538.1 CDS FTM_0799 NC_010677.1 869085 869285 D hypothetical protein 869085..869285 Francisella tularensis subsp. mediasiatica FSC147 6290104 YP_001891539.1 CDS FTM_0801 NC_010677.1 870894 871529 R membrane protein complement(870894..871529) Francisella tularensis subsp. mediasiatica FSC147 6290107 YP_001891540.1 CDS smpB NC_010677.1 872546 873019 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(872546..873019) Francisella tularensis subsp. mediasiatica FSC147 6290112 YP_001891541.1 CDS FTM_0804 NC_010677.1 873094 873525 D oligoketide cyclase/lipid transport protein 873094..873525 Francisella tularensis subsp. mediasiatica FSC147 6290114 YP_001891542.1 CDS FTM_0805 NC_010677.1 873525 873830 D hypothetical protein 873525..873830 Francisella tularensis subsp. mediasiatica FSC147 6290116 YP_001891543.1 CDS FTM_0806 NC_010677.1 873872 875077 D hypothetical protein 873872..875077 Francisella tularensis subsp. mediasiatica FSC147 6290117 YP_001891544.1 CDS FTM_0807 NC_010677.1 875154 876074 D VacJ like lipoprotein 875154..876074 Francisella tularensis subsp. mediasiatica FSC147 6290118 YP_001891545.1 CDS ggt NC_010677.1 876129 877934 D gamma-glutamyltranspeptidase 876129..877934 Francisella tularensis subsp. mediasiatica FSC147 6290119 YP_001891546.1 CDS FTM_0809 NC_010677.1 877950 878705 R methyltransferase complement(877950..878705) Francisella tularensis subsp. mediasiatica FSC147 6290121 YP_001891547.1 CDS FTM_0810 NC_010677.1 878877 880694 R GTP binding translational elongation factor Tu and G family protein complement(878877..880694) Francisella tularensis subsp. mediasiatica FSC147 6290123 YP_001891548.1 CDS FTM_0813 NC_010677.1 885119 885283 D membrane protein 885119..885283 Francisella tularensis subsp. mediasiatica FSC147 6290127 YP_001891549.1 CDS FTM_0814 NC_010677.1 885959 886168 D hypothetical protein 885959..886168 Francisella tularensis subsp. mediasiatica FSC147 6290128 YP_001891550.1 CDS FTM_0817 NC_010677.1 888113 889561 D type I restriction-modification system, M subunit 888113..889561 Francisella tularensis subsp. mediasiatica FSC147 6290132 YP_001891551.1 CDS FTM_0818 NC_010677.1 889551 891296 R hypothetical protein complement(889551..891296) Francisella tularensis subsp. mediasiatica FSC147 6290134 YP_001891552.1 CDS FTM_0819 NC_010677.1 891363 892235 R GTP-binding protein complement(891363..892235) Francisella tularensis subsp. mediasiatica FSC147 6290136 YP_001891553.1 CDS nagA NC_010677.1 892298 893431 D N-acetylglucosamine-6-phosphate deacetylase 892298..893431 Francisella tularensis subsp. mediasiatica FSC147 6290137 YP_001891554.1 CDS FTM_0821 NC_010677.1 893435 894073 D glycoprotease family protein 893435..894073 Francisella tularensis subsp. mediasiatica FSC147 6290138 YP_001891555.1 CDS FTM_0822 NC_010677.1 894077 894883 D glutamine amidotransferase 894077..894883 Francisella tularensis subsp. mediasiatica FSC147 6290143 YP_001891556.1 CDS FTM_0823 NC_010677.1 894893 896086 D aspartate aminotransferase 894893..896086 Francisella tularensis subsp. mediasiatica FSC147 6290145 YP_001891557.1 CDS era NC_010677.1 896200 897093 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 896200..897093 Francisella tularensis subsp. mediasiatica FSC147 6290147 YP_001891558.1 CDS FTM_0825 NC_010677.1 897108 897524 D membrane protein 897108..897524 Francisella tularensis subsp. mediasiatica FSC147 6290149 YP_001891559.1 CDS adk NC_010677.1 900861 901517 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(900861..901517) Francisella tularensis subsp. mediasiatica FSC147 6290152 YP_001891560.1 CDS pilM NC_010677.1 901644 902648 D type IV pili, pilus assembly protein 901644..902648 Francisella tularensis subsp. mediasiatica FSC147 6290153 YP_001891561.1 CDS pilN NC_010677.1 902650 903213 D type IV pili associated protein 902650..903213 Francisella tularensis subsp. mediasiatica FSC147 6290154 YP_001891562.1 CDS pilO NC_010677.1 903207 903803 D type IV pili glycosylation protein 903207..903803 Francisella tularensis subsp. mediasiatica FSC147 6290155 YP_001891563.1 CDS pilP NC_010677.1 903809 904399 D Type IV pili periplasmic component 903809..904399 Francisella tularensis subsp. mediasiatica FSC147 6290158 YP_001891564.1 CDS pilQ NC_010677.1 904412 906184 D type IV pili secretin component 904412..906184 Francisella tularensis subsp. mediasiatica FSC147 6290159 YP_001891565.1 CDS aroK NC_010677.1 906309 906839 D type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 906309..906839 Francisella tularensis subsp. mediasiatica FSC147 6290164 YP_001891566.1 CDS aroB NC_010677.1 906836 907915 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 906836..907915 Francisella tularensis subsp. mediasiatica FSC147 6290167 YP_001891567.1 CDS FTM_0835 NC_010677.1 907973 908197 D hypothetical protein 907973..908197 Francisella tularensis subsp. mediasiatica FSC147 6290168 YP_001891568.1 CDS FTM_0836 NC_010677.1 908264 908647 R hypothetical protein complement(908264..908647) Francisella tularensis subsp. mediasiatica FSC147 6290169 YP_001891569.1 CDS FTM_0837 NC_010677.1 908860 909147 D hypothetical protein 908860..909147 Francisella tularensis subsp. mediasiatica FSC147 6290171 YP_001891570.1 CDS putA NC_010677.1 909164 913228 D proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 909164..913228 Francisella tularensis subsp. mediasiatica FSC147 6290172 YP_001891571.1 CDS FTM_0839 NC_010677.1 913388 914896 D amino acid-polyamine-organocation (APC) superfamily 913388..914896 Francisella tularensis subsp. mediasiatica FSC147 6290173 YP_001891572.1 CDS FTM_0840 NC_010677.1 914972 916156 D major facilitator superfamily (MFS) transport protein 914972..916156 Francisella tularensis subsp. mediasiatica FSC147 6290174 YP_001891573.1 CDS dfp NC_010677.1 916169 917344 D phosphopantothenoylcysteine decarboxylase/phosphopantothenate cysteine ligase 916169..917344 Francisella tularensis subsp. mediasiatica FSC147 6290175 YP_001891574.1 CDS FTM_0843 NC_010677.1 918397 918651 R hypothetical protein complement(918397..918651) Francisella tularensis subsp. mediasiatica FSC147 6290177 YP_001891575.1 CDS FTM_0845 NC_010677.1 919693 919938 R hypothetical protein complement(919693..919938) Francisella tularensis subsp. mediasiatica FSC147 6290180 YP_001891576.1 CDS FTM_0850 NC_010677.1 923786 924592 D ROK family protein 923786..924592 Francisella tularensis subsp. mediasiatica FSC147 6290187 YP_001891577.1 CDS bioD NC_010677.1 925598 926275 R dethiobiotin synthase complement(925598..926275) Francisella tularensis subsp. mediasiatica FSC147 6290191 YP_001891578.1 CDS bioC NC_010677.1 926279 927016 R biotin synthesis protein BioC complement(926279..927016) Francisella tularensis subsp. mediasiatica FSC147 6290192 YP_001891579.1 CDS bioF NC_010677.1 926994 928121 R 8-amino-7-oxononanoate synthase complement(926994..928121) Francisella tularensis subsp. mediasiatica FSC147 6290193 YP_001891580.1 CDS bioB NC_010677.1 928115 929056 R biotin synthase complement(928115..929056) Francisella tularensis subsp. mediasiatica FSC147 6290195 YP_001891581.1 CDS bioA NC_010677.1 929103 930434 D adenosylmethionine-8-amino-7-oxononanoate aminotransferase 929103..930434 Francisella tularensis subsp. mediasiatica FSC147 6290197 YP_001891582.1 CDS glyA NC_010677.1 935361 936614 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(935361..936614) Francisella tularensis subsp. mediasiatica FSC147 6290214 YP_001891583.1 CDS FTM_0861 NC_010677.1 936718 937266 D hypothetical protein 936718..937266 Francisella tularensis subsp. mediasiatica FSC147 6290215 YP_001891584.1 CDS FTM_0862 NC_010677.1 937281 938552 R membrane protein complement(937281..938552) Francisella tularensis subsp. mediasiatica FSC147 6290219 YP_001891585.1 CDS FTM_0863 NC_010677.1 938760 940091 D membrane protein 938760..940091 Francisella tularensis subsp. mediasiatica FSC147 6290220 YP_001891586.1 CDS FTM_0864 NC_010677.1 940117 941007 R glycosyl transferase family protein complement(940117..941007) Francisella tularensis subsp. mediasiatica FSC147 6290226 YP_001891587.1 CDS FTM_0865 NC_010677.1 941015 942103 R hypothetical protein complement(941015..942103) Francisella tularensis subsp. mediasiatica FSC147 6290227 YP_001891588.1 CDS lpcC NC_010677.1 942273 943337 D glycosyl transferase family protein 942273..943337 Francisella tularensis subsp. mediasiatica FSC147 6290230 YP_001891589.1 CDS FTM_0867 NC_010677.1 943338 944435 R choloylglycine hydrolase family protein complement(943338..944435) Francisella tularensis subsp. mediasiatica FSC147 6290235 YP_001891590.1 CDS FTM_0868 NC_010677.1 944682 946073 D proton-dependent oligopeptide transporter disrupted by IS element 944682..946073 Francisella tularensis subsp. mediasiatica FSC147 6290236 YP_001891591.1 CDS FTM_0869 NC_010677.1 946895 947407 D hypothetical protein 946895..947407 Francisella tularensis subsp. mediasiatica FSC147 6290251 YP_001891592.1 CDS FTM_0870 NC_010677.1 947565 948194 R hypothetical protein complement(947565..948194) Francisella tularensis subsp. mediasiatica FSC147 6290257 YP_001891593.1 CDS FTM_0871 NC_010677.1 948838 949344 D hypothetical protein 948838..949344 Francisella tularensis subsp. mediasiatica FSC147 6290263 YP_001891594.1 CDS FTM_0873 NC_010677.1 952618 953418 D hypothetical protein 952618..953418 Francisella tularensis subsp. mediasiatica FSC147 6290267 YP_001891595.1 CDS FTM_0875 NC_010677.1 954242 956899 D type III restriction system endonuclease 954242..956899 Francisella tularensis subsp. mediasiatica FSC147 6290273 YP_001891596.1 CDS FTM_0876 NC_010677.1 956918 957448 D type III restriction enzyme, res subunit 956918..957448 Francisella tularensis subsp. mediasiatica FSC147 6290276 YP_001891597.1 CDS FTM_0877 NC_010677.1 957547 957888 D hypothetical protein 957547..957888 Francisella tularensis subsp. mediasiatica FSC147 6290278 YP_001891598.1 CDS FTM_0878 NC_010677.1 959208 960071 D hypothetical protein 959208..960071 Francisella tularensis subsp. mediasiatica FSC147 6290282 YP_001891599.1 CDS FTM_0880 NC_010677.1 961036 961590 D fatty acid hydroxylase 961036..961590 Francisella tularensis subsp. mediasiatica FSC147 6290285 YP_001891600.1 CDS rlmL NC_010677.1 961665 963818 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 961665..963818 Francisella tularensis subsp. mediasiatica FSC147 6290287 YP_001891601.1 CDS FTM_0882 NC_010677.1 963920 964318 D membrane protein 963920..964318 Francisella tularensis subsp. mediasiatica FSC147 6290288 YP_001891602.1 CDS fmt NC_010677.1 964323 965264 D methionyl-tRNA formyltransferase 964323..965264 Francisella tularensis subsp. mediasiatica FSC147 6290292 YP_001891603.1 CDS gshB NC_010677.1 965268 966242 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 965268..966242 Francisella tularensis subsp. mediasiatica FSC147 6290294 YP_001891604.1 CDS hemL NC_010677.1 966232 967527 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 966232..967527 Francisella tularensis subsp. mediasiatica FSC147 6290311 YP_001891605.1 CDS FTM_0886 NC_010677.1 967548 969215 R glycosyl hydrolase family protein complement(967548..969215) Francisella tularensis subsp. mediasiatica FSC147 6290316 YP_001891606.1 CDS hemF NC_010677.1 971461 972387 R catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase complement(971461..972387) Francisella tularensis subsp. mediasiatica FSC147 6290322 YP_001891607.1 CDS rpsF NC_010677.1 973066 973401 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 973066..973401 Francisella tularensis subsp. mediasiatica FSC147 6290326 YP_001891608.1 CDS rpsR NC_010677.1 973417 973635 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 973417..973635 Francisella tularensis subsp. mediasiatica FSC147 6290327 YP_001891609.1 CDS rplI NC_010677.1 973654 974109 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 973654..974109 Francisella tularensis subsp. mediasiatica FSC147 6290335 YP_001891610.1 CDS dnaB NC_010677.1 974199 975596 D replicative DNA helicase 974199..975596 Francisella tularensis subsp. mediasiatica FSC147 6290341 YP_001891611.1 CDS FTM_0895 NC_010677.1 975627 976739 D radical SAM protein 975627..976739 Francisella tularensis subsp. mediasiatica FSC147 6290530 YP_001891612.1 CDS pilF NC_010677.1 976729 977634 D Type IV pili, pilus assembly protein 976729..977634 Francisella tularensis subsp. mediasiatica FSC147 6290345 YP_001891613.1 CDS rsuA NC_010677.1 977627 978442 D 16S rRNA pseudouridine synthase 977627..978442 Francisella tularensis subsp. mediasiatica FSC147 6290347 YP_001891614.1 CDS FTM_0898 NC_010677.1 978442 978867 D hypothetical protein 978442..978867 Francisella tularensis subsp. mediasiatica FSC147 6290348 YP_001891615.1 CDS rimI NC_010677.1 978845 979285 D ribosomal-protein-alanine acetyltransferase 978845..979285 Francisella tularensis subsp. mediasiatica FSC147 6290351 YP_001891616.1 CDS FTM_0900 NC_010677.1 981726 981890 D hypothetical protein 981726..981890 Francisella tularensis subsp. mediasiatica FSC147 6290361 YP_001891617.1 CDS FTM_0904 NC_010677.1 986432 987055 D membrane protein 986432..987055 Francisella tularensis subsp. mediasiatica FSC147 6290369 YP_001891618.1 CDS FTM_0905 NC_010677.1 987136 987567 D hypothetical protein 987136..987567 Francisella tularensis subsp. mediasiatica FSC147 6290370 YP_001891619.1 CDS ispB NC_010677.1 987657 988634 D octaprenyl-diphosphate synthase 987657..988634 Francisella tularensis subsp. mediasiatica FSC147 6290372 YP_001891620.1 CDS FTM_0907 NC_010677.1 988652 989464 R fkbp-type peptidyl-prolyl cis-trans isomerase family protein complement(988652..989464) Francisella tularensis subsp. mediasiatica FSC147 6290382 YP_001891621.1 CDS FTM_0908 NC_010677.1 989478 990281 R ATPase complement(989478..990281) Francisella tularensis subsp. mediasiatica FSC147 6290383 YP_001891622.1 CDS FTM_0909 NC_010677.1 990274 990690 R thioesterase complement(990274..990690) Francisella tularensis subsp. mediasiatica FSC147 6290385 YP_001891623.1 CDS FTM_0910 NC_010677.1 990706 991317 R hypothetical protein complement(990706..991317) Francisella tularensis subsp. mediasiatica FSC147 6290386 YP_001891624.1 CDS FTM_0911 NC_010677.1 991318 992721 R serine-type D-Ala-D-Ala carboxypeptidase complement(991318..992721) Francisella tularensis subsp. mediasiatica FSC147 6290387 YP_001891625.1 CDS rpsU NC_010677.1 992977 993165 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 992977..993165 Francisella tularensis subsp. mediasiatica FSC147 6290389 YP_001891626.1 CDS FTM_0913 NC_010677.1 993240 993686 D GatB/YqeY domain-containing protein 993240..993686 Francisella tularensis subsp. mediasiatica FSC147 6290390 YP_001891627.1 CDS dnaG NC_010677.1 993707 995524 D DNA primase 993707..995524 Francisella tularensis subsp. mediasiatica FSC147 6290394 YP_001891628.1 CDS rpoD NC_010677.1 995549 997282 D RNA polymerase sigma-70 factor RpoD 995549..997282 Francisella tularensis subsp. mediasiatica FSC147 6290395 YP_001891629.1 CDS lipB NC_010677.1 1002746 1003366 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(1002746..1003366) Francisella tularensis subsp. mediasiatica FSC147 6290407 YP_001891630.1 CDS FTM_0920 NC_010677.1 1003376 1003660 R hypothetical protein complement(1003376..1003660) Francisella tularensis subsp. mediasiatica FSC147 6290408 YP_001891631.1 CDS FTM_0921 NC_010677.1 1003693 1005027 R D-alanyl-D-alanine carboxypeptidase complement(1003693..1005027) Francisella tularensis subsp. mediasiatica FSC147 6290410 YP_001891632.1 CDS ppa NC_010677.1 1005184 1005705 D inorganic pyrophosphatase 1005184..1005705 Francisella tularensis subsp. mediasiatica FSC147 6290411 YP_001891633.1 CDS yrbI NC_010677.1 1005796 1006344 D 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 1005796..1006344 Francisella tularensis subsp. mediasiatica FSC147 6290414 YP_001891634.1 CDS FTM_0924 NC_010677.1 1006352 1006978 D hypothetical protein 1006352..1006978 Francisella tularensis subsp. mediasiatica FSC147 6290415 YP_001891635.1 CDS FTM_0925 NC_010677.1 1006965 1007795 D hypothetical protein 1006965..1007795 Francisella tularensis subsp. mediasiatica FSC147 6290416 YP_001891636.1 CDS FTM_0926 NC_010677.1 1007869 1008600 D ABC transporter ATP-binding protein 1007869..1008600 Francisella tularensis subsp. mediasiatica FSC147 6290419 YP_001891637.1 CDS FTM_0927 NC_010677.1 1008649 1009242 D isomerase 1008649..1009242 Francisella tularensis subsp. mediasiatica FSC147 6290421 YP_001891638.1 CDS FTM_0928 NC_010677.1 1009255 1011087 D hypothetical protein 1009255..1011087 Francisella tularensis subsp. mediasiatica FSC147 6290423 YP_001891639.1 CDS truA NC_010677.1 1011090 1011866 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1011090..1011866 Francisella tularensis subsp. mediasiatica FSC147 6290424 YP_001891640.1 CDS FTM_0930 NC_010677.1 1011922 1013466 D amino acid permease 1011922..1013466 Francisella tularensis subsp. mediasiatica FSC147 6290425 YP_001891641.1 CDS guaA NC_010677.1 1013554 1015104 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1013554..1015104 Francisella tularensis subsp. mediasiatica FSC147 6290426 YP_001891642.1 CDS dxs NC_010677.1 1015186 1017033 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1015186..1017033 Francisella tularensis subsp. mediasiatica FSC147 6290428 YP_001891643.1 CDS FTM_0933 NC_010677.1 1017049 1017384 D hypothetical protein 1017049..1017384 Francisella tularensis subsp. mediasiatica FSC147 6290429 YP_001891644.1 CDS FTM_0934 NC_010677.1 1017603 1018034 D lipolytic enzyme, GDSL family 1017603..1018034 Francisella tularensis subsp. mediasiatica FSC147 6290606 YP_001891645.1 CDS FTM_0935 NC_010677.1 1018044 1018634 R hypothetical protein complement(1018044..1018634) Francisella tularensis subsp. mediasiatica FSC147 6290435 YP_001891646.1 CDS FTM_0936 NC_010677.1 1018752 1019477 D short chain dehydrogenase family protein 1018752..1019477 Francisella tularensis subsp. mediasiatica FSC147 6290437 YP_001891647.1 CDS ruvB NC_010677.1 1019541 1020587 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1019541..1020587 Francisella tularensis subsp. mediasiatica FSC147 6290438 YP_001891648.1 CDS FTM_0938 NC_010677.1 1020629 1021216 R peptidoglycan hydrolase complement(1020629..1021216) Francisella tularensis subsp. mediasiatica FSC147 6290439 YP_001891649.1 CDS FTM_0939 NC_010677.1 1021562 1021750 R hypothetical protein complement(1021562..1021750) Francisella tularensis subsp. mediasiatica FSC147 6290441 YP_001891650.1 CDS FTM_0940 NC_010677.1 1021862 1022065 R hypothetical protein complement(1021862..1022065) Francisella tularensis subsp. mediasiatica FSC147 6290443 YP_001891651.1 CDS FTM_0941 NC_010677.1 1022080 1022616 R membrane protein complement(1022080..1022616) Francisella tularensis subsp. mediasiatica FSC147 6290446 YP_001891652.1 CDS FTM_0942 NC_010677.1 1022776 1023693 D hypothetical protein 1022776..1023693 Francisella tularensis subsp. mediasiatica FSC147 6290447 YP_001891653.1 CDS FTM_0944 NC_010677.1 1025130 1026605 D proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 1025130..1026605 Francisella tularensis subsp. mediasiatica FSC147 6290449 YP_001891654.1 CDS FTM_0945 NC_010677.1 1026630 1027523 D drug/metabolite transporter superfamily protein 1026630..1027523 Francisella tularensis subsp. mediasiatica FSC147 6290453 YP_001891655.1 CDS pheS NC_010677.1 1027609 1028622 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1027609..1028622 Francisella tularensis subsp. mediasiatica FSC147 6290457 YP_001891656.1 CDS pheT NC_010677.1 1028643 1031015 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1028643..1031015 Francisella tularensis subsp. mediasiatica FSC147 6290460 YP_001891657.1 CDS FTM_0948 NC_010677.1 1031058 1031489 R Fe2+/Zn2+ uptake regulator protein complement(1031058..1031489) Francisella tularensis subsp. mediasiatica FSC147 6290462 YP_001891658.1 CDS FTM_0949 NC_010677.1 1031631 1032848 D hypothetical protein 1031631..1032848 Francisella tularensis subsp. mediasiatica FSC147 6290464 YP_001891659.1 CDS FTM_0950 NC_010677.1 1032851 1033597 D zinc (Zn2+)-iron (Fe2+) permease (ZIP) family protein 1032851..1033597 Francisella tularensis subsp. mediasiatica FSC147 6290466 YP_001891660.1 CDS FTM_0951 NC_010677.1 1033619 1034608 R lipoprotein complement(1033619..1034608) Francisella tularensis subsp. mediasiatica FSC147 6290472 YP_001891661.1 CDS cls NC_010677.1 1034777 1036207 R cardiolipin synthetase complement(1034777..1036207) Francisella tularensis subsp. mediasiatica FSC147 6290474 YP_001891662.1 CDS FTM_0955 NC_010677.1 1039091 1039951 D Mrp-like protein 1039091..1039951 Francisella tularensis subsp. mediasiatica FSC147 6290481 YP_001891663.1 CDS dcd NC_010677.1 1039963 1040529 D Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 1039963..1040529 Francisella tularensis subsp. mediasiatica FSC147 6290482 YP_001891664.1 CDS FTM_0957 NC_010677.1 1040536 1041726 R small conductance mechanosensitive ion channel (MscS) family protein complement(1040536..1041726) Francisella tularensis subsp. mediasiatica FSC147 6290483 YP_001891665.1 CDS FTM_0958 NC_010677.1 1041786 1042361 R rare lipoprotein B family protein complement(1041786..1042361) Francisella tularensis subsp. mediasiatica FSC147 6290484 YP_001891666.1 CDS leuS NC_010677.1 1042369 1044810 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(1042369..1044810) Francisella tularensis subsp. mediasiatica FSC147 6290486 YP_001891667.1 CDS FTM_0960 NC_010677.1 1044918 1046813 R hypothetical protein complement(1044918..1046813) Francisella tularensis subsp. mediasiatica FSC147 6290488 YP_001891668.1 CDS FTM_0962 NC_010677.1 1047602 1048012 R hypothetical protein complement(1047602..1048012) Francisella tularensis subsp. mediasiatica FSC147 6290492 YP_001891669.1 CDS FTM_0963 NC_010677.1 1048014 1048598 R hypothetical protein complement(1048014..1048598) Francisella tularensis subsp. mediasiatica FSC147 6290494 YP_001891670.1 CDS FTM_0965 NC_010677.1 1049234 1049605 R hypothetical protein complement(1049234..1049605) Francisella tularensis subsp. mediasiatica FSC147 6290497 YP_001891671.1 CDS FTM_0967 NC_010677.1 1050622 1051788 R hypothetical protein complement(1050622..1051788) Francisella tularensis subsp. mediasiatica FSC147 6290501 YP_001891672.1 CDS FTM_0968 NC_010677.1 1052133 1053362 R hypothetical protein complement(1052133..1053362) Francisella tularensis subsp. mediasiatica FSC147 6290502 YP_001891673.1 CDS FTM_0969 NC_010677.1 1053584 1054963 D amino acid transporter (AAT) family protein 1053584..1054963 Francisella tularensis subsp. mediasiatica FSC147 6290503 YP_001891674.1 CDS FTM_0970 NC_010677.1 1055005 1055610 D membrane protein 1055005..1055610 Francisella tularensis subsp. mediasiatica FSC147 6290504 YP_001891675.1 CDS FTM_0971 NC_010677.1 1055614 1055907 D transcriptional regulator, MarR family 1055614..1055907 Francisella tularensis subsp. mediasiatica FSC147 6290505 YP_001891676.1 CDS trxA2 NC_010677.1 1056304 1056630 R thioredoxin complement(1056304..1056630) Francisella tularensis subsp. mediasiatica FSC147 6290506 YP_001891677.1 CDS FTM_0973 NC_010677.1 1056634 1057323 R lipoprotein complement(1056634..1057323) Francisella tularensis subsp. mediasiatica FSC147 6290509 YP_001891678.1 CDS sufD NC_010677.1 1058279 1059424 R SufS activator complex, sufD subunit complement(1058279..1059424) Francisella tularensis subsp. mediasiatica FSC147 6290514 YP_001891679.1 CDS sufC NC_010677.1 1059437 1060186 R sufS activator complex, sufC subunit complement(1059437..1060186) Francisella tularensis subsp. mediasiatica FSC147 6290515 YP_001891680.1 CDS sufB NC_010677.1 1060229 1061671 R with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB complement(1060229..1061671) Francisella tularensis subsp. mediasiatica FSC147 6290516 YP_001891681.1 CDS FTM_0978 NC_010677.1 1061678 1062088 R FeS assembly SUF system regulator complement(1061678..1062088) Francisella tularensis subsp. mediasiatica FSC147 6290517 YP_001891682.1 CDS trkA NC_010677.1 1062241 1063614 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 1062241..1063614 Francisella tularensis subsp. mediasiatica FSC147 6290519 YP_001891683.1 CDS FTM_0980 NC_010677.1 1063673 1065094 D amino acid antiporter 1063673..1065094 Francisella tularensis subsp. mediasiatica FSC147 6290520 YP_001891684.1 CDS infA NC_010677.1 1066056 1066274 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(1066056..1066274) Francisella tularensis subsp. mediasiatica FSC147 6290522 YP_001891685.1 CDS FTM_0983 NC_010677.1 1066434 1067273 D hypothetical protein 1066434..1067273 Francisella tularensis subsp. mediasiatica FSC147 6290523 YP_001891686.1 CDS FTM_0984 NC_010677.1 1067270 1067536 D hypothetical protein 1067270..1067536 Francisella tularensis subsp. mediasiatica FSC147 6290524 YP_001891687.1 CDS ffh NC_010677.1 1067617 1068993 D signal recognition particle GTPase 1067617..1068993 Francisella tularensis subsp. mediasiatica FSC147 6290525 YP_001891688.1 CDS aroG NC_010677.1 1069025 1070137 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1069025..1070137 Francisella tularensis subsp. mediasiatica FSC147 6290526 YP_001891689.1 CDS xthA NC_010677.1 1072848 1073636 D exodeoxyribonuclease III 1072848..1073636 Francisella tularensis subsp. mediasiatica FSC147 6290051 YP_001891690.1 CDS FTM_0991 NC_010677.1 1073657 1074364 D short chain dehydrogenase 1073657..1074364 Francisella tularensis subsp. mediasiatica FSC147 6290531 YP_001891691.1 CDS FTM_0992 NC_010677.1 1074367 1074870 D putative kinase 1074367..1074870 Francisella tularensis subsp. mediasiatica FSC147 6290536 YP_001891692.1 CDS FTM_0993 NC_010677.1 1074870 1075589 D membrane protein 1074870..1075589 Francisella tularensis subsp. mediasiatica FSC147 6290541 YP_001891693.1 CDS gor NC_010677.1 1075627 1076988 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 1075627..1076988 Francisella tularensis subsp. mediasiatica FSC147 6290542 YP_001891694.1 CDS FTM_0995 NC_010677.1 1076999 1077319 D hypothetical protein 1076999..1077319 Francisella tularensis subsp. mediasiatica FSC147 6290546 YP_001891695.1 CDS FTM_0996 NC_010677.1 1077457 1078998 D proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 1077457..1078998 Francisella tularensis subsp. mediasiatica FSC147 6290548 YP_001891696.1 CDS FTM_0997 NC_010677.1 1078995 1080320 R ATP-dependent RNA helicase complement(1078995..1080320) Francisella tularensis subsp. mediasiatica FSC147 6290550 YP_001891697.1 CDS folE NC_010677.1 1080447 1081067 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1080447..1081067 Francisella tularensis subsp. mediasiatica FSC147 6290553 YP_001891698.1 CDS FTM_1000 NC_010677.1 1081914 1082339 D hypothetical protein 1081914..1082339 Francisella tularensis subsp. mediasiatica FSC147 6290557 YP_001891699.1 CDS FTM_1001 NC_010677.1 1082417 1083337 D carbon-nitrogen hydrolase family protein 1082417..1083337 Francisella tularensis subsp. mediasiatica FSC147 6290559 YP_001891700.1 CDS pabA NC_010677.1 1085715 1086269 R para-aminobenzoate synthase component complement(1085715..1086269) Francisella tularensis subsp. mediasiatica FSC147 6290567 YP_001891701.1 CDS FTM_1005 NC_010677.1 1086271 1088034 R para-aminobenzoate synthase component I complement(1086271..1088034) Francisella tularensis subsp. mediasiatica FSC147 6290569 YP_001891702.1 CDS FTM_1006 NC_010677.1 1088027 1089397 R AMP-binding protein complement(1088027..1089397) Francisella tularensis subsp. mediasiatica FSC147 6290572 YP_001891703.1 CDS folB NC_010677.1 1089479 1089832 D dihydroneopterin aldolase 1089479..1089832 Francisella tularensis subsp. mediasiatica FSC147 6290577 YP_001891704.1 CDS FTM_1008 NC_010677.1 1089834 1091096 D 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase/dihydropteroate synthase 1089834..1091096 Francisella tularensis subsp. mediasiatica FSC147 6290578 YP_001891705.1 CDS FTM_1009 NC_010677.1 1091109 1092029 D lipase/esterase 1091109..1092029 Francisella tularensis subsp. mediasiatica FSC147 6290580 YP_001891706.1 CDS FTM_1010 NC_010677.1 1092045 1092545 D hypothetical protein 1092045..1092545 Francisella tularensis subsp. mediasiatica FSC147 6290581 YP_001891707.1 CDS FTM_1012 NC_010677.1 1093889 1094884 R hypothetical protein complement(1093889..1094884) Francisella tularensis subsp. mediasiatica FSC147 6290583 YP_001891708.1 CDS FTM_1014 NC_010677.1 1096816 1097520 R hypothetical protein complement(1096816..1097520) Francisella tularensis subsp. mediasiatica FSC147 6290586 YP_001891709.1 CDS rplT NC_010677.1 1097551 1097916 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1097551..1097916) Francisella tularensis subsp. mediasiatica FSC147 6290587 YP_001891710.1 CDS rpmI NC_010677.1 1097952 1098149 R 50S ribosomal protein L35 complement(1097952..1098149) Francisella tularensis subsp. mediasiatica FSC147 6290588 YP_001891711.1 CDS infC NC_010677.1 1098192 1098704 R translation initiation factor IF-3 complement(1098192..1098704) Francisella tularensis subsp. mediasiatica FSC147 6290589 YP_001891712.1 CDS thrS NC_010677.1 1098735 1100639 R catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase complement(1098735..1100639) Francisella tularensis subsp. mediasiatica FSC147 6290590 YP_001891713.1 CDS FTM_1020 NC_010677.1 1102955 1103251 R hypothetical protein complement(1102955..1103251) Francisella tularensis subsp. mediasiatica FSC147 6290592 YP_001891714.1 CDS gcvH1 NC_010677.1 1103241 1103621 R glycine cleavage system H protein complement(1103241..1103621) Francisella tularensis subsp. mediasiatica FSC147 6290593 YP_001891715.1 CDS murG NC_010677.1 1103725 1104840 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1103725..1104840 Francisella tularensis subsp. mediasiatica FSC147 6290594 YP_001891716.1 CDS FTM_1023 NC_010677.1 1104850 1105188 D hypothetical protein 1104850..1105188 Francisella tularensis subsp. mediasiatica FSC147 6290595 YP_001891717.1 CDS recR NC_010677.1 1105188 1105790 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1105188..1105790 Francisella tularensis subsp. mediasiatica FSC147 6290596 YP_001891718.1 CDS spoT NC_010677.1 1105798 1107912 R GDP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase complement(1105798..1107912) Francisella tularensis subsp. mediasiatica FSC147 6290597 YP_001891719.1 CDS FTM_1026 NC_010677.1 1107981 1109192 R hypothetical protein complement(1107981..1109192) Francisella tularensis subsp. mediasiatica FSC147 6290599 YP_001891720.1 CDS capC NC_010677.1 1109194 1109658 R capsule biosynthesis protein CapC complement(1109194..1109658) Francisella tularensis subsp. mediasiatica FSC147 6290600 YP_001891721.1 CDS capB NC_010677.1 1109683 1110900 R capsule biosynthesis protein CapB complement(1109683..1110900) Francisella tularensis subsp. mediasiatica FSC147 6290601 YP_001891722.1 CDS FTM_1029 NC_010677.1 1110976 1112211 R major facilitator superfamily protein complement(1110976..1112211) Francisella tularensis subsp. mediasiatica FSC147 6290602 YP_001891723.1 CDS ans NC_010677.1 1112905 1113768 R asparaginase complement(1112905..1113768) Francisella tularensis subsp. mediasiatica FSC147 6290609 YP_001891724.1 CDS cphB NC_010677.1 1113984 1114802 R cyanophycinase complement(1113984..1114802) Francisella tularensis subsp. mediasiatica FSC147 6290610 YP_001891725.1 CDS FTM_1037 NC_010677.1 1115005 1116111 D ribokinase, pfkB family protein 1115005..1116111 Francisella tularensis subsp. mediasiatica FSC147 6290611 YP_001891726.1 CDS FTM_1038 NC_010677.1 1116389 1117051 R haloacid dehalogenase-like hydrolase complement(1116389..1117051) Francisella tularensis subsp. mediasiatica FSC147 6290612 YP_001891727.1 CDS FTM_1039 NC_010677.1 1117070 1118083 R glycosyl transferase family protein complement(1117070..1118083) Francisella tularensis subsp. mediasiatica FSC147 6290613 YP_001891728.1 CDS FTM_1040 NC_010677.1 1118086 1119093 R glycosyl transferase family 2 protein complement(1118086..1119093) Francisella tularensis subsp. mediasiatica FSC147 6290614 YP_001891729.1 CDS FTM_1041 NC_010677.1 1119110 1120069 R glycosyl transferase family 2 protein complement(1119110..1120069) Francisella tularensis subsp. mediasiatica FSC147 6290615 YP_001891730.1 CDS FTM_1042 NC_010677.1 1120078 1120761 R hypothetical protein complement(1120078..1120761) Francisella tularensis subsp. mediasiatica FSC147 6290617 YP_001891731.1 CDS FTM_1043 NC_010677.1 1120843 1121472 R methyltransferase domain-containing protein complement(1120843..1121472) Francisella tularensis subsp. mediasiatica FSC147 6290618 YP_001891732.1 CDS FTM_1044 NC_010677.1 1121465 1122751 R hypothetical protein complement(1121465..1122751) Francisella tularensis subsp. mediasiatica FSC147 6290619 YP_001891733.1 CDS FTM_1045 NC_010677.1 1122765 1124447 R ATP-binding cassette (ABC) superfamily protein complement(1122765..1124447) Francisella tularensis subsp. mediasiatica FSC147 6290620 YP_001891734.1 CDS FTM_1046 NC_010677.1 1124444 1125673 R glycosyl transferase family protein complement(1124444..1125673) Francisella tularensis subsp. mediasiatica FSC147 6290621 YP_001891735.1 CDS galE NC_010677.1 1125677 1126696 R UDP-glucose 4-epimerase complement(1125677..1126696) Francisella tularensis subsp. mediasiatica FSC147 6290622 YP_001891736.1 CDS FTM_1048 NC_010677.1 1126689 1128083 R lipopolysaccharide synthesis sugar transferase complement(1126689..1128083) Francisella tularensis subsp. mediasiatica FSC147 6290623 YP_001891737.1 CDS rpe NC_010677.1 1128064 1128732 R D-ribulose-phosphate 3-epimerase complement(1128064..1128732) Francisella tularensis subsp. mediasiatica FSC147 6290921 YP_001891738.1 CDS kpsF NC_010677.1 1128869 1129840 D phosphosugar isomerase 1128869..1129840 Francisella tularensis subsp. mediasiatica FSC147 6290624 YP_001891739.1 CDS FTM_1052 NC_010677.1 1130344 1131042 R hypothetical protein complement(1130344..1131042) Francisella tularensis subsp. mediasiatica FSC147 6290627 YP_001891740.1 CDS FTM_1053 NC_010677.1 1131039 1131854 R hypothetical protein complement(1131039..1131854) Francisella tularensis subsp. mediasiatica FSC147 6290635 YP_001891741.1 CDS FTM_1055 NC_010677.1 1132193 1133155 R metallo-beta-lactamase superfamily protein complement(1132193..1133155) Francisella tularensis subsp. mediasiatica FSC147 6290639 YP_001891742.1 CDS fabI NC_010677.1 1133302 1134084 R enoyl-ACP reductase I complement(1133302..1134084) Francisella tularensis subsp. mediasiatica FSC147 6290645 YP_001891743.1 CDS FTM_1057 NC_010677.1 1134360 1135073 D hypothetical protein 1134360..1135073 Francisella tularensis subsp. mediasiatica FSC147 6290650 YP_001891744.1 CDS dnaJ NC_010677.1 1138003 1139190 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(1138003..1139190) Francisella tularensis subsp. mediasiatica FSC147 6291191 YP_001891745.1 CDS dnaK NC_010677.1 1139216 1141144 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(1139216..1141144) Francisella tularensis subsp. mediasiatica FSC147 6290675 YP_001891746.1 CDS grpE NC_010677.1 1141245 1141832 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(1141245..1141832) Francisella tularensis subsp. mediasiatica FSC147 6290680 YP_001891747.1 CDS mltA NC_010677.1 1141921 1143087 D membrane-bound lytic murein transglycosylase A 1141921..1143087 Francisella tularensis subsp. mediasiatica FSC147 6290681 YP_001891748.1 CDS hemG NC_010677.1 1143080 1144264 D protoporphyrinogen oxidase 1143080..1144264 Francisella tularensis subsp. mediasiatica FSC147 6290686 YP_001891749.1 CDS rplM NC_010677.1 1144403 1144831 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1144403..1144831 Francisella tularensis subsp. mediasiatica FSC147 6290687 YP_001891750.1 CDS rpsI NC_010677.1 1144847 1145236 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1144847..1145236 Francisella tularensis subsp. mediasiatica FSC147 6290688 YP_001891751.1 CDS mglA NC_010677.1 1145296 1145913 D macrophage growth locus, subunit A 1145296..1145913 Francisella tularensis subsp. mediasiatica FSC147 6290689 YP_001891752.1 CDS mglB NC_010677.1 1145915 1146322 D ClpXP protease specificity-enhancing factor 1145915..1146322 Francisella tularensis subsp. mediasiatica FSC147 6290691 YP_001891753.1 CDS FTM_1069 NC_010677.1 1146350 1147588 R sodium-solute symporter family protein complement(1146350..1147588) Francisella tularensis subsp. mediasiatica FSC147 6290697 YP_001891754.1 CDS rnhB NC_010677.1 1147581 1148144 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(1147581..1148144) Francisella tularensis subsp. mediasiatica FSC147 6290704 YP_001891755.1 CDS FTM_1071 NC_010677.1 1148146 1148889 R SpoU family rRNA methyltransferase complement(1148146..1148889) Francisella tularensis subsp. mediasiatica FSC147 6290707 YP_001891756.1 CDS ptsN NC_010677.1 1148882 1149337 R PEP-dependent sugar phosphotransferase system complement(1148882..1149337) Francisella tularensis subsp. mediasiatica FSC147 6290708 YP_001891757.1 CDS FTM_1073 NC_010677.1 1149374 1149670 R sigma54 modulation protein complement(1149374..1149670) Francisella tularensis subsp. mediasiatica FSC147 6290712 YP_001891758.1 CDS FTM_1074 NC_010677.1 1149789 1150034 D hypothetical protein 1149789..1150034 Francisella tularensis subsp. mediasiatica FSC147 6290714 YP_001891759.1 CDS trmE NC_010677.1 1150040 1151392 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1150040..1151392 Francisella tularensis subsp. mediasiatica FSC147 6290715 YP_001891760.1 CDS FTM_1076 NC_010677.1 1151402 1151596 R hypothetical protein complement(1151402..1151596) Francisella tularensis subsp. mediasiatica FSC147 6290719 YP_001891761.1 CDS cysK NC_010677.1 1153916 1154839 D cysteine synthase 1153916..1154839 Francisella tularensis subsp. mediasiatica FSC147 6290726 YP_001891762.1 CDS FTM_1080 NC_010677.1 1155101 1155670 D disulfide bond formation protein DsbB family 1155101..1155670 Francisella tularensis subsp. mediasiatica FSC147 6290728 YP_001891763.1 CDS pdpA1 NC_010677.1 1161310 1163772 D hypothetical protein 1161310..1163772 Francisella tularensis subsp. mediasiatica FSC147 6290737 YP_001891764.1 CDS pdpB1 NC_010677.1 1163777 1167058 D hypothetical protein 1163777..1167058 Francisella tularensis subsp. mediasiatica FSC147 6290740 YP_001891765.1 CDS FTM_1088 NC_010677.1 1167048 1167425 D lipoprotein 1167048..1167425 Francisella tularensis subsp. mediasiatica FSC147 6290741 YP_001891766.1 CDS FTM_1089 NC_010677.1 1167438 1167932 D hypothetical protein 1167438..1167932 Francisella tularensis subsp. mediasiatica FSC147 6290743 YP_001891767.1 CDS FTM_1090 NC_010677.1 1167937 1169601 D hypothetical protein 1167937..1169601 Francisella tularensis subsp. mediasiatica FSC147 6289974 YP_001891768.1 CDS FTM_1091 NC_010677.1 1169669 1170190 D hypothetical protein 1169669..1170190 Francisella tularensis subsp. mediasiatica FSC147 6290745 YP_001891769.1 CDS FTM_1092 NC_010677.1 1170203 1171633 D hypothetical protein 1170203..1171633 Francisella tularensis subsp. mediasiatica FSC147 6290746 YP_001891770.1 CDS FTM_1093 NC_010677.1 1171646 1172263 D hypothetical protein 1171646..1172263 Francisella tularensis subsp. mediasiatica FSC147 6290748 YP_001891771.1 CDS FTM_1094 NC_010677.1 1172285 1173436 D hypothetical protein 1172285..1173436 Francisella tularensis subsp. mediasiatica FSC147 6290750 YP_001891772.1 CDS FTM_1095 NC_010677.1 1173402 1174175 D hypothetical protein 1173402..1174175 Francisella tularensis subsp. mediasiatica FSC147 6290754 YP_001891773.1 CDS pdpC1 NC_010677.1 1174215 1178201 D PdpC 1174215..1178201 Francisella tularensis subsp. mediasiatica FSC147 6290761 YP_001891774.1 CDS FTM_1097 NC_010677.1 1178219 1178794 D hypothetical protein 1178219..1178794 Francisella tularensis subsp. mediasiatica FSC147 6290763 YP_001891775.1 CDS iglD1 NC_010677.1 1178801 1179997 R intracellular growth locus protein D complement(1178801..1179997) Francisella tularensis subsp. mediasiatica FSC147 6290766 YP_001891776.1 CDS iglC1 NC_010677.1 1180018 1180647 R intracellular growth locus C protein complement(1180018..1180647) Francisella tularensis subsp. mediasiatica FSC147 6291276 YP_001891777.1 CDS iglB1 NC_010677.1 1180664 1182184 R intracellular growth locus protein B complement(1180664..1182184) Francisella tularensis subsp. mediasiatica FSC147 6290770 YP_001891778.1 CDS iglA1 NC_010677.1 1182198 1182752 R intracellular growth locus protein A complement(1182198..1182752) Francisella tularensis subsp. mediasiatica FSC147 6290771 YP_001891779.1 CDS pdpD1 NC_010677.1 1182833 1186564 R hypothetical protein complement(1182833..1186564) Francisella tularensis subsp. mediasiatica FSC147 6290775 YP_001891780.1 CDS anmK NC_010677.1 1186795 1187778 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(1186795..1187778) Francisella tularensis subsp. mediasiatica FSC147 6290776 YP_001891781.1 CDS FTM_1106 NC_010677.1 1190083 1190505 R lipoprotein complement(1190083..1190505) Francisella tularensis subsp. mediasiatica FSC147 6290782 YP_001891782.1 CDS nadE NC_010677.1 1190609 1191358 R NAD+ synthetase complement(1190609..1191358) Francisella tularensis subsp. mediasiatica FSC147 6290784 YP_001891783.1 CDS FTM_1108 NC_010677.1 1191487 1192959 R outer membrane efflux protein complement(1191487..1192959) Francisella tularensis subsp. mediasiatica FSC147 6290786 YP_001891784.1 CDS FTM_1109 NC_010677.1 1192969 1193991 R membrane fusion protein complement(1192969..1193991) Francisella tularensis subsp. mediasiatica FSC147 6290788 YP_001891785.1 CDS FTM_1110 NC_010677.1 1194013 1195542 R drug:H+ antiporter-1 (DHA2) family protein complement(1194013..1195542) Francisella tularensis subsp. mediasiatica FSC147 6290790 YP_001891786.1 CDS FTM_1111 NC_010677.1 1195707 1196534 D transcriptional regulator AraC family protein 1195707..1196534 Francisella tularensis subsp. mediasiatica FSC147 6290792 YP_001891787.1 CDS FTM_1112 NC_010677.1 1196522 1198213 R long chain fatty acid CoA ligase complement(1196522..1198213) Francisella tularensis subsp. mediasiatica FSC147 6290798 YP_001891788.1 CDS FTM_1113 NC_010677.1 1198321 1199802 R proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter complement(1198321..1199802) Francisella tularensis subsp. mediasiatica FSC147 6290799 YP_001891789.1 CDS FTM_1114 NC_010677.1 1200039 1200767 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE complement(1200039..1200767) Francisella tularensis subsp. mediasiatica FSC147 6290800 YP_001891790.1 CDS FTM_1115 NC_010677.1 1200838 1201524 D hypothetical protein 1200838..1201524 Francisella tularensis subsp. mediasiatica FSC147 6290806 YP_001891791.1 CDS FTM_1116 NC_010677.1 1201514 1202212 R hypothetical protein complement(1201514..1202212) Francisella tularensis subsp. mediasiatica FSC147 6290807 YP_001891792.1 CDS FTM_1117 NC_010677.1 1202217 1202942 R hypothetical protein complement(1202217..1202942) Francisella tularensis subsp. mediasiatica FSC147 6290809 YP_001891793.1 CDS FTM_1118 NC_010677.1 1202952 1203713 R ATP-binding Cassette (ABC) superfamily protein complement(1202952..1203713) Francisella tularensis subsp. mediasiatica FSC147 6290810 YP_001891794.1 CDS FTM_1119 NC_010677.1 1203728 1204828 R ABC-type transport system permease protein complement(1203728..1204828) Francisella tularensis subsp. mediasiatica FSC147 6290812 YP_001891795.1 CDS rluD NC_010677.1 1205693 1206691 R ribosomal large subunit pseudouridine synthase D complement(1205693..1206691) Francisella tularensis subsp. mediasiatica FSC147 6290820 YP_001891796.1 CDS comL NC_010677.1 1206780 1207604 D competence lipoprotein ComL 1206780..1207604 Francisella tularensis subsp. mediasiatica FSC147 6290822 YP_001891797.1 CDS serC NC_010677.1 1209114 1210166 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1209114..1210166 Francisella tularensis subsp. mediasiatica FSC147 6290825 YP_001891798.1 CDS cmk NC_010677.1 1210153 1210818 D cytidylate kinase 1210153..1210818 Francisella tularensis subsp. mediasiatica FSC147 6290826 YP_001891799.1 CDS FTM_1127 NC_010677.1 1210835 1211446 R short chain dehydrogenase complement(1210835..1211446) Francisella tularensis subsp. mediasiatica FSC147 6290829 YP_001891800.1 CDS FTM_1128 NC_010677.1 1211449 1211973 R peroxiredoxin, AhpC-TSA family protein complement(1211449..1211973) Francisella tularensis subsp. mediasiatica FSC147 6290830 YP_001891801.1 CDS oxyR NC_010677.1 1212071 1212940 D oxidative stress transcriptional regulator 1212071..1212940 Francisella tularensis subsp. mediasiatica FSC147 6290831 YP_001891802.1 CDS FTM_1130 NC_010677.1 1212943 1213674 R hypothetical protein complement(1212943..1213674) Francisella tularensis subsp. mediasiatica FSC147 6290833 YP_001891803.1 CDS FTM_1131 NC_010677.1 1213688 1213960 R hypothetical protein complement(1213688..1213960) Francisella tularensis subsp. mediasiatica FSC147 6290836 YP_001891804.1 CDS FTM_1132 NC_010677.1 1214029 1214808 R hypothetical protein complement(1214029..1214808) Francisella tularensis subsp. mediasiatica FSC147 6290837 YP_001891805.1 CDS FTM_1135 NC_010677.1 1217739 1219148 R hypothetical protein complement(1217739..1219148) Francisella tularensis subsp. mediasiatica FSC147 6290846 YP_001891806.1 CDS vanY NC_010677.1 1219135 1219608 R D-alanyl-D-alanine carboxypeptidase complement(1219135..1219608) Francisella tularensis subsp. mediasiatica FSC147 6290847 YP_001891807.1 CDS dnaQ NC_010677.1 1219602 1220294 R DNA polymerase III subunit epsilon complement(1219602..1220294) Francisella tularensis subsp. mediasiatica FSC147 6290850 YP_001891808.1 CDS FTM_1139 NC_010677.1 1221840 1222055 R membrane protein complement(1221840..1222055) Francisella tularensis subsp. mediasiatica FSC147 6290856 YP_001891809.1 CDS phnA NC_010677.1 1222061 1222330 R phosphonoacetate hydrolase complement(1222061..1222330) Francisella tularensis subsp. mediasiatica FSC147 6290860 YP_001891810.1 CDS FTM_1142 NC_010677.1 1223940 1224539 R peroxiredoxin of the AhpC/TSA family complement(1223940..1224539) Francisella tularensis subsp. mediasiatica FSC147 6290865 YP_001891811.1 CDS FTM_1143 NC_010677.1 1224631 1225212 D haloacid dehalogenase-like hydrolase 1224631..1225212 Francisella tularensis subsp. mediasiatica FSC147 6290866 YP_001891812.1 CDS FTM_1144 NC_010677.1 1225265 1226767 D hypothetical protein 1225265..1226767 Francisella tularensis subsp. mediasiatica FSC147 6290302 YP_001891813.1 CDS FTM_1146 NC_010677.1 1227585 1228070 D hypothetical protein 1227585..1228070 Francisella tularensis subsp. mediasiatica FSC147 6290973 YP_001891814.1 CDS FTM_1147 NC_010677.1 1228163 1228798 R ubiquinone biosynthesis protein complement(1228163..1228798) Francisella tularensis subsp. mediasiatica FSC147 6290261 YP_001891815.1 CDS FTM_1148 NC_010677.1 1228814 1229326 R major facilitator superfamily (MFS) transport protein complement(1228814..1229326) Francisella tularensis subsp. mediasiatica FSC147 6290054 YP_001891816.1 CDS mdh NC_010677.1 1229477 1230436 D Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 1229477..1230436 Francisella tularensis subsp. mediasiatica FSC147 6291327 YP_001891817.1 CDS nrdA NC_010677.1 1230640 1232412 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1230640..1232412 Francisella tularensis subsp. mediasiatica FSC147 6291600 YP_001891818.1 CDS grxA NC_010677.1 1232416 1232676 D glutaredoxin 1232416..1232676 Francisella tularensis subsp. mediasiatica FSC147 6291432 YP_001891819.1 CDS FTM_1152 NC_010677.1 1232683 1233915 D bifunctional gluaredoxin/ribonucleoside-diphosphate reductase subunit beta 1232683..1233915 Francisella tularensis subsp. mediasiatica FSC147 6291192 YP_001891820.1 CDS FTM_1154 NC_010677.1 1235914 1236516 D DJ-1/PfpI family protein 1235914..1236516 Francisella tularensis subsp. mediasiatica FSC147 6290380 YP_001891821.1 CDS FTM_1155 NC_010677.1 1236523 1237572 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1236523..1237572 Francisella tularensis subsp. mediasiatica FSC147 6290196 YP_001891822.1 CDS FTM_1158 NC_010677.1 1239028 1239684 R hypothetical protein complement(1239028..1239684) Francisella tularensis subsp. mediasiatica FSC147 6290318 YP_001891823.1 CDS FTM_1161 NC_010677.1 1241193 1243280 R N-6 DNA Methylase family complement(1241193..1243280) Francisella tularensis subsp. mediasiatica FSC147 6290452 YP_001891824.1 CDS FTM_1162 NC_010677.1 1243510 1244493 R tRNA-dihydrouridine synthase complement(1243510..1244493) Francisella tularensis subsp. mediasiatica FSC147 6291283 YP_001891825.1 CDS prmA NC_010677.1 1244483 1245328 R 50S ribosomal protein L11 methyltransferase complement(1244483..1245328) Francisella tularensis subsp. mediasiatica FSC147 6290498 YP_001891826.1 CDS yghD NC_010677.1 1245551 1246708 R Fe-dependent alcohol dehydrogenase YqhD complement(1245551..1246708) Francisella tularensis subsp. mediasiatica FSC147 6291239 YP_001891827.1 CDS lldD NC_010677.1 1249841 1250983 R L-lactate dehydrogenase complement(1249841..1250983) Francisella tularensis subsp. mediasiatica FSC147 6291151 YP_001891828.1 CDS tyrS NC_010677.1 1252233 1253423 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(1252233..1253423) Francisella tularensis subsp. mediasiatica FSC147 6290817 YP_001891829.1 CDS lplA NC_010677.1 1253537 1254439 D lipoate-protein ligase A 1253537..1254439 Francisella tularensis subsp. mediasiatica FSC147 6291476 YP_001891830.1 CDS FTM_1169 NC_010677.1 1254442 1255191 R membrane protein complement(1254442..1255191) Francisella tularensis subsp. mediasiatica FSC147 6291016 YP_001891831.1 CDS hslV NC_010677.1 1255383 1255934 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 1255383..1255934 Francisella tularensis subsp. mediasiatica FSC147 6290727 YP_001891832.1 CDS hslU NC_010677.1 1255942 1257309 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 1255942..1257309 Francisella tularensis subsp. mediasiatica FSC147 6290289 YP_001891833.1 CDS FTM_1173 NC_010677.1 1258943 1260100 D potassium channel protein 1258943..1260100 Francisella tularensis subsp. mediasiatica FSC147 6290683 YP_001891834.1 CDS udhA NC_010677.1 1260196 1261596 D catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 1260196..1261596 Francisella tularensis subsp. mediasiatica FSC147 6290299 YP_001891835.1 CDS pilD NC_010677.1 1261627 1262418 D Type IV pili leader peptidase and methylase 1261627..1262418 Francisella tularensis subsp. mediasiatica FSC147 6291317 YP_001891836.1 CDS FTM_1176 NC_010677.1 1262458 1263303 D hypothetical protein 1262458..1263303 Francisella tularensis subsp. mediasiatica FSC147 6290883 YP_001891837.1 CDS blaA NC_010677.1 1263312 1264196 D beta-lactamase class A 1263312..1264196 Francisella tularensis subsp. mediasiatica FSC147 6291433 YP_001891838.1 CDS pth NC_010677.1 1264189 1264764 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1264189..1264764 Francisella tularensis subsp. mediasiatica FSC147 6290458 YP_001891839.1 CDS ychF NC_010677.1 1264783 1265874 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1264783..1265874 Francisella tularensis subsp. mediasiatica FSC147 6290223 YP_001891840.1 CDS FTM_1180 NC_010677.1 1265889 1266164 D lipoprotein 1265889..1266164 Francisella tularensis subsp. mediasiatica FSC147 6291631 YP_001891841.1 CDS FTM_1182 NC_010677.1 1267754 1269013 R transporter-associated protein, HlyC/CorC family complement(1267754..1269013) Francisella tularensis subsp. mediasiatica FSC147 6290969 YP_001891842.1 CDS rplY NC_010677.1 1269109 1269399 R the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 complement(1269109..1269399) Francisella tularensis subsp. mediasiatica FSC147 6290275 YP_001891843.1 CDS prsA NC_010677.1 1269499 1270467 R ribose-phosphate pyrophosphokinase complement(1269499..1270467) Francisella tularensis subsp. mediasiatica FSC147 6291001 YP_001891844.1 CDS FTM_1187 NC_010677.1 1272968 1274245 R major facilitator superfamily protein complement(1272968..1274245) Francisella tularensis subsp. mediasiatica FSC147 6291700 YP_001891845.1 CDS FTM_1189 NC_010677.1 1275356 1276531 R monovalent cation:proton antiporter family protein complement(1275356..1276531) Francisella tularensis subsp. mediasiatica FSC147 6291144 YP_001891846.1 CDS FTM_1190 NC_010677.1 1276629 1277261 R nicotinamide ribonucleoside (NR) uptake permease (PnuC) family protein complement(1276629..1277261) Francisella tularensis subsp. mediasiatica FSC147 6290684 YP_001891847.1 CDS FTM_1191 NC_010677.1 1277261 1277764 R isochorismatase family protein complement(1277261..1277764) Francisella tularensis subsp. mediasiatica FSC147 6291443 YP_001891848.1 CDS FTM_1193 NC_010677.1 1278565 1279263 D aldolase/adducin class II family protein 1278565..1279263 Francisella tularensis subsp. mediasiatica FSC147 6291204 YP_001891849.1 CDS hdc NC_010677.1 1279278 1280414 D catalyzes the formation of histamine from L-histidine; histidine decarboxylase 1279278..1280414 Francisella tularensis subsp. mediasiatica FSC147 6290298 YP_001891850.1 CDS FTM_1195 NC_010677.1 1280401 1281213 R hypothetical protein complement(1280401..1281213) Francisella tularensis subsp. mediasiatica FSC147 6290778 YP_001891851.1 CDS FTM_1197 NC_010677.1 1281869 1282165 D hypothetical protein 1281869..1282165 Francisella tularensis subsp. mediasiatica FSC147 6290648 YP_001891852.1 CDS FTM_1198 NC_010677.1 1282187 1282774 R membrane protein complement(1282187..1282774) Francisella tularensis subsp. mediasiatica FSC147 6291268 YP_001891853.1 CDS FTM_1199 NC_010677.1 1282823 1284238 R DNA recombination protein RmuC family protein complement(1282823..1284238) Francisella tularensis subsp. mediasiatica FSC147 6291397 YP_001891854.1 CDS ruvA NC_010677.1 1284264 1284914 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(1284264..1284914) Francisella tularensis subsp. mediasiatica FSC147 6290773 YP_001891855.1 CDS FTM_1201 NC_010677.1 1284927 1286120 R sugar transporter, MFS superfamily complement(1284927..1286120) Francisella tularensis subsp. mediasiatica FSC147 6291506 YP_001891856.1 CDS ruvC NC_010677.1 1286202 1286717 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(1286202..1286717) Francisella tularensis subsp. mediasiatica FSC147 6291171 YP_001891857.1 CDS FTM_1203 NC_010677.1 1286814 1287560 R hypothetical protein complement(1286814..1287560) Francisella tularensis subsp. mediasiatica FSC147 6291651 YP_001891858.1 CDS FTM_1204 NC_010677.1 1287576 1288235 R isoprenoid biosynthesis protein with amidotransferase-like domain complement(1287576..1288235) Francisella tularensis subsp. mediasiatica FSC147 6290384 YP_001891859.1 CDS lipA NC_010677.1 1288265 1289248 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(1288265..1289248) Francisella tularensis subsp. mediasiatica FSC147 6290999 YP_001891860.1 CDS ftnA NC_010677.1 1289455 1289955 D ferric iron binding protein, ferritin-like protein 1289455..1289955 Francisella tularensis subsp. mediasiatica FSC147 6291036 YP_001891861.1 CDS FTM_1207 NC_010677.1 1289958 1291526 R proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter complement(1289958..1291526) Francisella tularensis subsp. mediasiatica FSC147 6290942 YP_001891862.1 CDS grxB NC_010677.1 1291588 1292232 D cofactor involved in the reduction of disulfides; glutaredoxin 1291588..1292232 Francisella tularensis subsp. mediasiatica FSC147 6290218 YP_001891863.1 CDS rnfB NC_010677.1 1292234 1292863 D iron-sulfur cluster-binding protein 1292234..1292863 Francisella tularensis subsp. mediasiatica FSC147 6290818 YP_001891864.1 CDS nth NC_010677.1 1292856 1293494 D endonuclease III 1292856..1293494 Francisella tularensis subsp. mediasiatica FSC147 6291515 YP_001891865.1 CDS FTM_1211 NC_010677.1 1293491 1293919 D hypothetical protein 1293491..1293919 Francisella tularensis subsp. mediasiatica FSC147 6291035 YP_001891866.1 CDS FTM_1212 NC_010677.1 1293919 1295178 D membrane protein 1293919..1295178 Francisella tularensis subsp. mediasiatica FSC147 6291624 YP_001891867.1 CDS FTM_1213 NC_010677.1 1295294 1295980 D hypothetical protein 1295294..1295980 Francisella tularensis subsp. mediasiatica FSC147 6290537 YP_001891868.1 CDS mfd NC_010677.1 1296025 1299450 D transcription-repair coupling factor 1296025..1299450 Francisella tularensis subsp. mediasiatica FSC147 6290412 YP_001891869.1 CDS ilvN NC_010677.1 1300644 1300961 R acetolactate synthase small subunit complement(1300644..1300961) Francisella tularensis subsp. mediasiatica FSC147 6290642 YP_001891870.1 CDS ilvD NC_010677.1 1302806 1304488 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(1302806..1304488) Francisella tularensis subsp. mediasiatica FSC147 6290456 YP_001891871.1 CDS FTM_1220 NC_010677.1 1307899 1308126 D transcriptional regulator 1307899..1308126 Francisella tularensis subsp. mediasiatica FSC147 6290291 YP_001891872.1 CDS FTM_1221 NC_010677.1 1308129 1309487 D transcriptional regulator 1308129..1309487 Francisella tularensis subsp. mediasiatica FSC147 6290676 YP_001891873.1 CDS FTM_1222 NC_010677.1 1309509 1310690 R hypothetical protein complement(1309509..1310690) Francisella tularensis subsp. mediasiatica FSC147 6291412 YP_001891874.1 CDS FTM_1223 NC_010677.1 1310705 1310965 R hypothetical protein complement(1310705..1310965) Francisella tularensis subsp. mediasiatica FSC147 6291450 YP_001891875.1 CDS FTM_1227 NC_010677.1 1313317 1313574 R hypothetical protein complement(1313317..1313574) Francisella tularensis subsp. mediasiatica FSC147 6291025 YP_001891876.1 CDS rdgC NC_010677.1 1313579 1314439 R Required for efficient pilin antigenic variation; recombination associated protein complement(1313579..1314439) Francisella tularensis subsp. mediasiatica FSC147 6290329 YP_001891877.1 CDS FTM_1229 NC_010677.1 1314629 1315615 D putative rhodanese, sulfurtransferase 1314629..1315615 Francisella tularensis subsp. mediasiatica FSC147 6291372 YP_001891878.1 CDS rep NC_010677.1 1316632 1318647 R UvrD/REP superfamily I DNA and RNA helicase complement(1316632..1318647) Francisella tularensis subsp. mediasiatica FSC147 6290371 YP_001891879.1 CDS FTM_1232 NC_010677.1 1318641 1319387 R hypothetical protein complement(1318641..1319387) Francisella tularensis subsp. mediasiatica FSC147 6290945 YP_001891880.1 CDS FTM_1233 NC_010677.1 1320009 1320512 D isochorismatase hydrolase family protein 1320009..1320512 Francisella tularensis subsp. mediasiatica FSC147 6291345 YP_001891881.1 CDS FTM_1235 NC_010677.1 1321200 1321688 D isochorismatase hydrolase family protein 1321200..1321688 Francisella tularensis subsp. mediasiatica FSC147 6291648 YP_001891882.1 CDS FTM_1236 NC_010677.1 1321838 1322296 R hypothetical protein complement(1321838..1322296) Francisella tularensis subsp. mediasiatica FSC147 6291355 YP_001891883.1 CDS talA NC_010677.1 1322319 1323284 R transaldolase B complement(1322319..1323284) Francisella tularensis subsp. mediasiatica FSC147 6290871 YP_001891884.1 CDS pepB NC_010677.1 1323422 1324801 R cytosol aminopeptidase complement(1323422..1324801) Francisella tularensis subsp. mediasiatica FSC147 6290747 YP_001891885.1 CDS FTM_1239 NC_010677.1 1324804 1326186 R putative outer membrane efflux protein complement(1324804..1326186) Francisella tularensis subsp. mediasiatica FSC147 6290796 YP_001891886.1 CDS alaS NC_010677.1 1326194 1328791 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1326194..1328791) Francisella tularensis subsp. mediasiatica FSC147 6290534 YP_001891887.1 CDS FTM_1241 NC_010677.1 1328947 1329393 D hypothetical protein 1328947..1329393 Francisella tularensis subsp. mediasiatica FSC147 6291373 YP_001891888.1 CDS FTM_1243 NC_010677.1 1331481 1331816 R hypothetical protein complement(1331481..1331816) Francisella tularensis subsp. mediasiatica FSC147 6290772 YP_001891889.1 CDS FTM_1244 NC_010677.1 1331847 1332254 D hypothetical protein 1331847..1332254 Francisella tularensis subsp. mediasiatica FSC147 6291678 YP_001891890.1 CDS FTM_1247 NC_010677.1 1333741 1334862 D protein-disulfide isomerase 1333741..1334862 Francisella tularensis subsp. mediasiatica FSC147 6291563 YP_001891891.1 CDS FTM_1249 NC_010677.1 1336311 1337165 R this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae; bifunctional methionine sulfoxide reductase B/A protein complement(1336311..1337165) Francisella tularensis subsp. mediasiatica FSC147 6290716 YP_001891892.1 CDS betT NC_010677.1 1337762 1339714 R betaine/carnitine/choline transporter (BCCT) family protein complement(1337762..1339714) Francisella tularensis subsp. mediasiatica FSC147 6291441 YP_001891893.1 CDS spoU NC_010677.1 1339856 1340608 D rRNA methyltransferase 1339856..1340608 Francisella tularensis subsp. mediasiatica FSC147 6290701 YP_001891894.1 CDS FTM_1253 NC_010677.1 1340702 1341649 D choloylglycine hydrolase family protein 1340702..1341649 Francisella tularensis subsp. mediasiatica FSC147 6291282 YP_001891895.1 CDS FTM_1254 NC_010677.1 1341814 1342167 D hypothetical protein 1341814..1342167 Francisella tularensis subsp. mediasiatica FSC147 6291562 YP_001891896.1 CDS FTM_1256 NC_010677.1 1343989 1344282 R hypothetical protein complement(1343989..1344282) Francisella tularensis subsp. mediasiatica FSC147 6290755 YP_001891897.1 CDS fopA NC_010677.1 1350948 1352126 R outer membrane protein FopA complement(1350948..1352126) Francisella tularensis subsp. mediasiatica FSC147 6290229 YP_001891898.1 CDS FTM_1262 NC_010677.1 1352236 1352481 R 4Fe-4S ferredoxin complement(1352236..1352481) Francisella tularensis subsp. mediasiatica FSC147 6291337 YP_001891899.1 CDS coaD NC_010677.1 1352486 1352974 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(1352486..1352974) Francisella tularensis subsp. mediasiatica FSC147 6290632 YP_001891900.1 CDS FTM_1264 NC_010677.1 1352986 1353537 R hypothetical protein complement(1352986..1353537) Francisella tularensis subsp. mediasiatica FSC147 6290463 YP_001891901.1 CDS FTM_1265 NC_010677.1 1353551 1353907 R hypothetical protein complement(1353551..1353907) Francisella tularensis subsp. mediasiatica FSC147 6291429 YP_001891902.1 CDS sufS NC_010677.1 1353928 1355151 R selenocysteine lyase complement(1353928..1355151) Francisella tularensis subsp. mediasiatica FSC147 6290934 YP_001891903.1 CDS sdaA NC_010677.1 1355254 1356627 R L-serine dehydratase complement(1355254..1356627) Francisella tularensis subsp. mediasiatica FSC147 6291489 YP_001891904.1 CDS FTM_1268 NC_010677.1 1356683 1357351 R metal-dependent hydrolase complement(1356683..1357351) Francisella tularensis subsp. mediasiatica FSC147 6291330 YP_001891905.1 CDS pheA NC_010677.1 1357377 1358219 R prephenate dehydratase complement(1357377..1358219) Francisella tularensis subsp. mediasiatica FSC147 6291123 YP_001891906.1 CDS alr NC_010677.1 1359994 1361091 R alanine racemase complement(1359994..1361091) Francisella tularensis subsp. mediasiatica FSC147 6291127 YP_001891907.1 CDS FTM_1272 NC_010677.1 1361104 1362597 R proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter complement(1361104..1362597) Francisella tularensis subsp. mediasiatica FSC147 6290024 YP_001891908.1 CDS FTM_1273 NC_010677.1 1362722 1363429 R hypothetical protein complement(1362722..1363429) Francisella tularensis subsp. mediasiatica FSC147 6290739 YP_001891909.1 CDS FTM_1274 NC_010677.1 1363441 1363836 R hypothetical protein complement(1363441..1363836) Francisella tularensis subsp. mediasiatica FSC147 6290401 YP_001891910.1 CDS FTM_1275 NC_010677.1 1363923 1364945 D hypothetical protein 1363923..1364945 Francisella tularensis subsp. mediasiatica FSC147 6291418 YP_001891911.1 CDS serB NC_010677.1 1364934 1365584 R phosphoserine phosphatase complement(1364934..1365584) Francisella tularensis subsp. mediasiatica FSC147 6290471 YP_001891912.1 CDS FTM_1277 NC_010677.1 1366198 1367655 D proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 1366198..1367655 Francisella tularensis subsp. mediasiatica FSC147 6291310 YP_001891913.1 CDS FTM_1278 NC_010677.1 1367784 1368047 R hypothetical protein complement(1367784..1368047) Francisella tularensis subsp. mediasiatica FSC147 6290539 YP_001891914.1 CDS rpoH NC_010677.1 1368983 1369861 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(1368983..1369861) Francisella tularensis subsp. mediasiatica FSC147 6290478 YP_001891915.1 CDS FTM_1280 NC_010677.1 1369885 1370373 R hypothetical protein complement(1369885..1370373) Francisella tularensis subsp. mediasiatica FSC147 6291375 YP_001891916.1 CDS secF NC_010677.1 1370447 1371391 R forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF complement(1370447..1371391) Francisella tularensis subsp. mediasiatica FSC147 6291536 YP_001891917.1 CDS secD NC_010677.1 1371410 1373347 R part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD complement(1371410..1373347) Francisella tularensis subsp. mediasiatica FSC147 6291638 YP_001891918.1 CDS yajC NC_010677.1 1373404 1373760 R preprotein translocase subunit YajC complement(1373404..1373760) Francisella tularensis subsp. mediasiatica FSC147 6290692 YP_001891919.1 CDS FTM_1284 NC_010677.1 1374316 1374888 R isochorismatase hydrolase family protein complement(1374316..1374888) Francisella tularensis subsp. mediasiatica FSC147 6290813 YP_001891920.1 CDS tgt NC_010677.1 1376739 1377842 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(1376739..1377842) Francisella tularensis subsp. mediasiatica FSC147 6290427 YP_001891921.1 CDS FTM_1289 NC_010677.1 1378825 1379091 R hypothetical protein complement(1378825..1379091) Francisella tularensis subsp. mediasiatica FSC147 6290667 YP_001891922.1 CDS FTM_1290 NC_010677.1 1379247 1379588 R hypothetical protein complement(1379247..1379588) Francisella tularensis subsp. mediasiatica FSC147 6290019 YP_001891923.1 CDS FTM_1291 NC_010677.1 1380224 1380838 D hypothetical protein 1380224..1380838 Francisella tularensis subsp. mediasiatica FSC147 6290186 YP_001891924.1 CDS metIQ NC_010677.1 1381854 1383326 D methionine uptake transporter (MUT) family protein, membrane and periplasmic protein 1381854..1383326 Francisella tularensis subsp. mediasiatica FSC147 6291377 YP_001891925.1 CDS FTM_1294 NC_010677.1 1383397 1384608 D hydroxy/aromatic amino acid permease (HAAAP) family protein 1383397..1384608 Francisella tularensis subsp. mediasiatica FSC147 6290157 YP_001891926.1 CDS FTM_1295 NC_010677.1 1384683 1385438 D rhodanese-like family protein 1384683..1385438 Francisella tularensis subsp. mediasiatica FSC147 6291118 YP_001891927.1 CDS ispF NC_010677.1 1385445 1385924 D catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1385445..1385924 Francisella tularensis subsp. mediasiatica FSC147 6290532 YP_001891928.1 CDS FTM_1297 NC_010677.1 1385929 1387614 R Mur ligase family protein complement(1385929..1387614) Francisella tularensis subsp. mediasiatica FSC147 6290558 YP_001891929.1 CDS cphA NC_010677.1 1387640 1390462 R catalyze the formation of cyanophycin which may act to store excess nitrogen; cyanophycin synthetase complement(1387640..1390462) Francisella tularensis subsp. mediasiatica FSC147 6290100 YP_001891930.1 CDS glpQ NC_010677.1 1391317 1392069 R glycerophosphoryl diester phosphodiesterase complement(1391317..1392069) Francisella tularensis subsp. mediasiatica FSC147 6290738 YP_001891931.1 CDS pilB NC_010677.1 1392227 1394005 D Type IV pili ATPase 1392227..1394005 Francisella tularensis subsp. mediasiatica FSC147 6290760 YP_001891932.1 CDS pilC NC_010677.1 1394020 1395249 D Type IV pili polytopic inner membrane protein 1394020..1395249 Francisella tularensis subsp. mediasiatica FSC147 6290744 YP_001891933.1 CDS FTM_1304 NC_010677.1 1396500 1396889 R hypothetical protein complement(1396500..1396889) Francisella tularensis subsp. mediasiatica FSC147 6291186 YP_001891934.1 CDS FTM_1305 NC_010677.1 1396852 1397112 R hypothetical protein complement(1396852..1397112) Francisella tularensis subsp. mediasiatica FSC147 6290926 YP_001891935.1 CDS hemH NC_010677.1 1397246 1398247 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1397246..1398247 Francisella tularensis subsp. mediasiatica FSC147 6290971 YP_001891936.1 CDS uvrC NC_010677.1 1402085 1403923 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(1402085..1403923) Francisella tularensis subsp. mediasiatica FSC147 6291420 YP_001891937.1 CDS rnd NC_010677.1 1404032 1405126 D ribonuclease D 1404032..1405126 Francisella tularensis subsp. mediasiatica FSC147 6291080 YP_001891938.1 CDS FTM_1313 NC_010677.1 1405155 1406369 D drug:H+ antiporter-1 (DHA1) family protein 1405155..1406369 Francisella tularensis subsp. mediasiatica FSC147 6291551 YP_001891939.1 CDS FTM_1314 NC_010677.1 1406366 1406743 R hypothetical protein complement(1406366..1406743) Francisella tularensis subsp. mediasiatica FSC147 6291583 YP_001891940.1 CDS rpmA NC_010677.1 1407130 1407384 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(1407130..1407384) Francisella tularensis subsp. mediasiatica FSC147 6291585 YP_001891941.1 CDS rplU NC_010677.1 1407415 1407729 R 50S ribosomal protein L21 complement(1407415..1407729) Francisella tularensis subsp. mediasiatica FSC147 6291607 YP_001891942.1 CDS secA NC_010677.1 1409797 1412517 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(1409797..1412517) Francisella tularensis subsp. mediasiatica FSC147 6290549 YP_001891943.1 CDS FTM_1320 NC_010677.1 1412649 1413677 D hypothetical protein 1412649..1413677 Francisella tularensis subsp. mediasiatica FSC147 6291591 YP_001891944.1 CDS FTM_1321 NC_010677.1 1413681 1414130 D hypothetical protein 1413681..1414130 Francisella tularensis subsp. mediasiatica FSC147 6290188 YP_001891945.1 CDS deoD NC_010677.1 1414127 1414849 R purine nucleoside phosphorylase complement(1414127..1414849) Francisella tularensis subsp. mediasiatica FSC147 6291367 YP_001891946.1 CDS hflB NC_010677.1 1415910 1417856 R ATP-dependent metalloprotease complement(1415910..1417856) Francisella tularensis subsp. mediasiatica FSC147 6290062 YP_001891947.1 CDS uvrA NC_010677.1 1419461 1422283 R excinuclease ABC subunit A complement(1419461..1422283) Francisella tularensis subsp. mediasiatica FSC147 6290254 YP_001891948.1 CDS greA NC_010677.1 1422322 1422804 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(1422322..1422804) Francisella tularensis subsp. mediasiatica FSC147 6291161 YP_001891949.1 CDS fimT NC_010677.1 1422838 1423422 R type IV pili, pilus assembly protein complement(1422838..1423422) Francisella tularensis subsp. mediasiatica FSC147 6290430 YP_001891950.1 CDS pgi NC_010677.1 1423423 1425045 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(1423423..1425045) Francisella tularensis subsp. mediasiatica FSC147 6290631 YP_001891951.1 CDS FTM_1329 NC_010677.1 1425032 1425685 R thiamine pyrophosphokinase complement(1425032..1425685) Francisella tularensis subsp. mediasiatica FSC147 6290090 YP_001891952.1 CDS guaB NC_010677.1 1425751 1427211 R IMP dehydrogenase/GMP reductase complement(1425751..1427211) Francisella tularensis subsp. mediasiatica FSC147 6290690 YP_001891953.1 CDS pepA NC_010677.1 1427312 1428751 R cytosol aminopeptidase complement(1427312..1428751) Francisella tularensis subsp. mediasiatica FSC147 6290540 YP_001891954.1 CDS FTM_1332 NC_010677.1 1428917 1429999 D hypothetical protein 1428917..1429999 Francisella tularensis subsp. mediasiatica FSC147 6291662 YP_001891955.1 CDS FTM_1333 NC_010677.1 1429999 1431060 D YjgP/YjgQ family permease 1429999..1431060 Francisella tularensis subsp. mediasiatica FSC147 6290142 YP_001891956.1 CDS FTM_1334 NC_010677.1 1431068 1432321 D metallopeptidase M16 family protein 1431068..1432321 Francisella tularensis subsp. mediasiatica FSC147 6291340 YP_001891957.1 CDS FTM_1335 NC_010677.1 1432328 1433551 D Zn-dependent peptidase M16 family protein 1432328..1433551 Francisella tularensis subsp. mediasiatica FSC147 6291667 YP_001891958.1 CDS FTM_1336 NC_010677.1 1433552 1434130 D N6-adenine-specific methylase 1433552..1434130 Francisella tularensis subsp. mediasiatica FSC147 6290305 YP_001891959.1 CDS FTM_1337 NC_010677.1 1434164 1434814 D hypothetical protein 1434164..1434814 Francisella tularensis subsp. mediasiatica FSC147 6290556 YP_001891960.1 CDS miaE NC_010677.1 1434867 1435478 R tRNA-(ms(2)io(6)A)-hydroxylase complement(1434867..1435478) Francisella tularensis subsp. mediasiatica FSC147 6290485 YP_001891961.1 CDS udp NC_010677.1 1435594 1436397 D uridine phosphorylase 1435594..1436397 Francisella tularensis subsp. mediasiatica FSC147 6290487 YP_001891962.1 CDS cdd NC_010677.1 1436418 1436819 D cytidine deaminase 1436418..1436819 Francisella tularensis subsp. mediasiatica FSC147 6291129 YP_001891963.1 CDS FTM_1342 NC_010677.1 1437017 1440046 R 4Fe-4S ferredoxin complement(1437017..1440046) Francisella tularensis subsp. mediasiatica FSC147 6290150 YP_001891964.1 CDS gpmI NC_010677.1 1440264 1441802 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 1440264..1441802 Francisella tularensis subsp. mediasiatica FSC147 6290643 YP_001891965.1 CDS serS NC_010677.1 1441817 1443097 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1441817..1443097 Francisella tularensis subsp. mediasiatica FSC147 6290671 YP_001891966.1 CDS cscK NC_010677.1 1443207 1444106 D ROK family protein 1443207..1444106 Francisella tularensis subsp. mediasiatica FSC147 6290139 YP_001891967.1 CDS FTM_1346 NC_010677.1 1444184 1445443 D multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) transporter 1444184..1445443 Francisella tularensis subsp. mediasiatica FSC147 6290295 YP_001891968.1 CDS FTM_1347 NC_010677.1 1445447 1445647 R hypothetical protein complement(1445447..1445647) Francisella tularensis subsp. mediasiatica FSC147 6290473 YP_001891969.1 CDS FTM_1348 NC_010677.1 1445675 1446184 R hypothetical protein complement(1445675..1446184) Francisella tularensis subsp. mediasiatica FSC147 6290413 YP_001891970.1 CDS cydD NC_010677.1 1446561 1448342 D in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1446561..1448342 Francisella tularensis subsp. mediasiatica FSC147 6290160 YP_001891971.1 CDS cydC NC_010677.1 1448339 1449988 D in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1448339..1449988 Francisella tularensis subsp. mediasiatica FSC147 6291056 YP_001891972.1 CDS dctA NC_010677.1 1449990 1451240 R aerobic C4-dicarboxylate transport protein complement(1449990..1451240) Francisella tularensis subsp. mediasiatica FSC147 6290995 YP_001891973.1 CDS FTM_1352 NC_010677.1 1451379 1451759 R endoribonuclease L-PSP complement(1451379..1451759) Francisella tularensis subsp. mediasiatica FSC147 6290076 YP_001891974.1 CDS FTM_1354 NC_010677.1 1453577 1454695 R ABC transporter membrane protein complement(1453577..1454695) Francisella tularensis subsp. mediasiatica FSC147 6290101 YP_001891975.1 CDS FTM_1356 NC_010677.1 1455621 1456424 R hypothetical protein complement(1455621..1456424) Francisella tularensis subsp. mediasiatica FSC147 6291187 YP_001891976.1 CDS ugpQ NC_010677.1 1456730 1457764 D glycerophosphoryl diester phosphodiesterase family protein 1456730..1457764 Francisella tularensis subsp. mediasiatica FSC147 6291556 YP_001891977.1 CDS glpT NC_010677.1 1457871 1459187 D glycerol-3-phosphate transporter 1457871..1459187 Francisella tularensis subsp. mediasiatica FSC147 6291523 YP_001891978.1 CDS katG NC_010677.1 1463195 1465420 D peroxidase/catalase 1463195..1465420 Francisella tularensis subsp. mediasiatica FSC147 6290122 YP_001891979.1 CDS FTM_1362 NC_010677.1 1465524 1466849 D dGTP triphosphohydrolase 1465524..1466849 Francisella tularensis subsp. mediasiatica FSC147 6291230 YP_001891980.1 CDS FTM_1363 NC_010677.1 1466833 1468053 R metabolite:H+ symporter (MHS) family protein complement(1466833..1468053) Francisella tularensis subsp. mediasiatica FSC147 6290039 YP_001891981.1 CDS FTM_1364 NC_010677.1 1468114 1468458 R hypothetical protein complement(1468114..1468458) Francisella tularensis subsp. mediasiatica FSC147 6290307 YP_001891982.1 CDS upp NC_010677.1 1469466 1470095 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(1469466..1470095) Francisella tularensis subsp. mediasiatica FSC147 6290058 YP_001891983.1 CDS chiA NC_010677.1 1470289 1472619 R chitinase, glycosyl hydrolase family 18 complement(1470289..1472619) Francisella tularensis subsp. mediasiatica FSC147 6290508 YP_001891984.1 CDS kbl NC_010677.1 1473153 1474349 D catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 1473153..1474349 Francisella tularensis subsp. mediasiatica FSC147 6290851 YP_001891985.1 CDS tdh NC_010677.1 1474372 1475427 D converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 1474372..1475427 Francisella tularensis subsp. mediasiatica FSC147 6290512 YP_001891986.1 CDS FTM_1370 NC_010677.1 1475429 1476691 D serine permease 1475429..1476691 Francisella tularensis subsp. mediasiatica FSC147 6290194 YP_001891987.1 CDS ispD NC_010677.1 1476696 1477385 R 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(1476696..1477385) Francisella tularensis subsp. mediasiatica FSC147 6290140 YP_001891988.1 CDS ftsB NC_010677.1 1477375 1477665 R cell division protein, septum formation initiator complement(1477375..1477665) Francisella tularensis subsp. mediasiatica FSC147 6289983 YP_001891989.1 CDS eno NC_010677.1 1477673 1479043 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(1477673..1479043) Francisella tularensis subsp. mediasiatica FSC147 6290135 YP_001891990.1 CDS FTM_1374 NC_010677.1 1479152 1480390 R major facilitator superfamily (MFS) transport protein complement(1479152..1480390) Francisella tularensis subsp. mediasiatica FSC147 6290538 YP_001891991.1 CDS FTM_1375 NC_010677.1 1480493 1481257 R nicotinamide mononucleotide transport (NMT) family protein complement(1480493..1481257) Francisella tularensis subsp. mediasiatica FSC147 6291073 YP_001891992.1 CDS FTM_1376 NC_010677.1 1481277 1482224 R ROK family protein complement(1481277..1482224) Francisella tularensis subsp. mediasiatica FSC147 6290031 YP_001891993.1 CDS FTM_1377 NC_010677.1 1482224 1483189 R ROK family protein complement(1482224..1483189) Francisella tularensis subsp. mediasiatica FSC147 6290368 YP_001891994.1 CDS rumA NC_010677.1 1483199 1484548 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(1483199..1484548) Francisella tularensis subsp. mediasiatica FSC147 6291116 YP_001891995.1 CDS FTM_1379 NC_010677.1 1484637 1485209 R hypothetical protein complement(1484637..1485209) Francisella tularensis subsp. mediasiatica FSC147 6291095 YP_001891996.1 CDS rpoZ NC_010677.1 1485474 1485692 R DNA-directed RNA polymerase subunit omega complement(1485474..1485692) Francisella tularensis subsp. mediasiatica FSC147 6291384 YP_001891997.1 CDS udk NC_010677.1 1485685 1486350 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(1485685..1486350) Francisella tularensis subsp. mediasiatica FSC147 6291698 YP_001891998.1 CDS kdsA NC_010677.1 1486361 1487188 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(1486361..1487188) Francisella tularensis subsp. mediasiatica FSC147 6290912 YP_001891999.1 CDS FTM_1384 NC_010677.1 1487219 1487569 R essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA complement(1487219..1487569) Francisella tularensis subsp. mediasiatica FSC147 6291565 YP_001892000.1 CDS pnp NC_010677.1 1487575 1489656 R polynucleotide phosphorylase/polyadenylase complement(1487575..1489656) Francisella tularensis subsp. mediasiatica FSC147 6290630 YP_001892001.1 CDS rpsO NC_010677.1 1489712 1489978 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(1489712..1489978) Francisella tularensis subsp. mediasiatica FSC147 6290915 YP_001892002.1 CDS ftsI NC_010677.1 1490085 1491779 R cell division protein, peptidoglycan synthetase (PBP) complement(1490085..1491779) Francisella tularensis subsp. mediasiatica FSC147 6290980 YP_001892003.1 CDS FTM_1388 NC_010677.1 1491772 1492122 R hypothetical protein complement(1491772..1492122) Francisella tularensis subsp. mediasiatica FSC147 6290332 YP_001892004.1 CDS mraW NC_010677.1 1492119 1493036 R S-adenosyl-methyltransferase MraW complement(1492119..1493036) Francisella tularensis subsp. mediasiatica FSC147 6290084 YP_001892005.1 CDS FTM_1390 NC_010677.1 1493042 1495141 R hypothetical protein complement(1493042..1495141) Francisella tularensis subsp. mediasiatica FSC147 6291173 YP_001892006.1 CDS mutM NC_010677.1 1495235 1496059 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 1495235..1496059 Francisella tularensis subsp. mediasiatica FSC147 6290141 YP_001892007.1 CDS FTM_1392 NC_010677.1 1496888 1497427 R with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT complement(1496888..1497427) Francisella tularensis subsp. mediasiatica FSC147 6291314 YP_001892008.1 CDS FTM_1393 NC_010677.1 1497430 1498293 R with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS complement(1497430..1498293) Francisella tularensis subsp. mediasiatica FSC147 6291645 YP_001892009.1 CDS gyrB NC_010677.1 1498423 1500834 R DNA gyrase subunit B complement(1498423..1500834) Francisella tularensis subsp. mediasiatica FSC147 6291641 YP_001892010.1 CDS FTM_1395 NC_010677.1 1501016 1501816 D hypothetical protein 1501016..1501816 Francisella tularensis subsp. mediasiatica FSC147 6290274 YP_001892011.1 CDS FTM_1396 NC_010677.1 1501850 1502833 D tRNA-dihydrouridine synthase A 1501850..1502833 Francisella tularensis subsp. mediasiatica FSC147 6290315 YP_001892012.1 CDS FTM_1397 NC_010677.1 1502840 1503607 R protein-disulfide isomerase complement(1502840..1503607) Francisella tularensis subsp. mediasiatica FSC147 6290780 YP_001892013.1 CDS FTM_1399 NC_010677.1 1504597 1506510 R hypothetical protein complement(1504597..1506510) Francisella tularensis subsp. mediasiatica FSC147 6291656 YP_001892014.1 CDS sucC NC_010677.1 1506680 1507843 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1506680..1507843 Francisella tularensis subsp. mediasiatica FSC147 6290313 YP_001892015.1 CDS sucD NC_010677.1 1507875 1508747 D succinyl-CoA ligase [ADP-forming] subunit alpha 1507875..1508747 Francisella tularensis subsp. mediasiatica FSC147 6289986 YP_001892016.1 CDS FTM_1402 NC_010677.1 1508859 1509284 D membrane protein 1508859..1509284 Francisella tularensis subsp. mediasiatica FSC147 6291145 YP_001892017.1 CDS FTM_1403 NC_010677.1 1509667 1510707 D hypothetical protein 1509667..1510707 Francisella tularensis subsp. mediasiatica FSC147 6291693 YP_001892018.1 CDS FTM_1404 NC_010677.1 1510839 1512056 R hypothetical protein complement(1510839..1512056) Francisella tularensis subsp. mediasiatica FSC147 6290802 YP_001892019.1 CDS FTM_1405 NC_010677.1 1512286 1513731 D proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 1512286..1513731 Francisella tularensis subsp. mediasiatica FSC147 6290711 YP_001892020.1 CDS FTM_1406 NC_010677.1 1513735 1514655 D asparaginase 1513735..1514655 Francisella tularensis subsp. mediasiatica FSC147 6290280 YP_001892021.1 CDS FTM_1408 NC_010677.1 1515432 1515935 R hypothetical protein complement(1515432..1515935) Francisella tularensis subsp. mediasiatica FSC147 6290665 YP_001892022.1 CDS cutC NC_010677.1 1516268 1516990 D copper homeostasis protein CutC family protein 1516268..1516990 Francisella tularensis subsp. mediasiatica FSC147 6291306 YP_001892023.1 CDS araJ NC_010677.1 1517033 1518172 R hypothetical protein complement(1517033..1518172) Francisella tularensis subsp. mediasiatica FSC147 6290983 YP_001892024.1 CDS gph NC_010677.1 1519246 1519920 D phosphoglycolate phosphatase 1519246..1519920 Francisella tularensis subsp. mediasiatica FSC147 6289971 YP_001892025.1 CDS trxB NC_010677.1 1521271 1522221 D thioredoxin reductase 1521271..1522221 Francisella tularensis subsp. mediasiatica FSC147 6290392 YP_001892026.1 CDS FTM_1415 NC_010677.1 1522329 1523495 D major facilitator superfamily (MFS) transport protein 1522329..1523495 Francisella tularensis subsp. mediasiatica FSC147 6291379 YP_001892027.1 CDS mutL NC_010677.1 1524593 1526395 R DNA mismatch repair enzyme with ATPase activity complement(1524593..1526395) Francisella tularensis subsp. mediasiatica FSC147 6290493 YP_001892028.1 CDS FTM_1418 NC_010677.1 1526403 1527065 R hypothetical protein complement(1526403..1527065) Francisella tularensis subsp. mediasiatica FSC147 6291241 YP_001892029.1 CDS FTM_1419 NC_010677.1 1527133 1527852 R hypothetical protein complement(1527133..1527852) Francisella tularensis subsp. mediasiatica FSC147 6290082 YP_001892030.1 CDS FTM_1420 NC_010677.1 1528006 1528893 D GTPase 1528006..1528893 Francisella tularensis subsp. mediasiatica FSC147 6290095 YP_001892031.1 CDS FTM_1421 NC_010677.1 1529110 1529925 D lipoprotein 1529110..1529925 Francisella tularensis subsp. mediasiatica FSC147 6290843 YP_001892032.1 CDS potF NC_010677.1 1530178 1531359 R ATP-binding cassette putrescine uptake system, periplasmic protein complement(1530178..1531359) Francisella tularensis subsp. mediasiatica FSC147 6290045 YP_001892033.1 CDS FTM_1423 NC_010677.1 1531443 1532852 D amino acid-polyamine-organocation (APC) superfamily protein 1531443..1532852 Francisella tularensis subsp. mediasiatica FSC147 6290467 YP_001892034.1 CDS perM NC_010677.1 1532954 1534060 D PerM family protein 1532954..1534060 Francisella tularensis subsp. mediasiatica FSC147 6290252 YP_001892035.1 CDS recJ NC_010677.1 1534054 1535796 D single-stranded-DNA-specific exonuclease RecJ 1534054..1535796 Francisella tularensis subsp. mediasiatica FSC147 6290490 YP_001892036.1 CDS FTM_1426 NC_010677.1 1535793 1536575 D birA-like protein 1535793..1536575 Francisella tularensis subsp. mediasiatica FSC147 6290002 YP_001892037.1 CDS FTM_1427 NC_010677.1 1536572 1537495 D tRNA synthetase 1536572..1537495 Francisella tularensis subsp. mediasiatica FSC147 6290993 YP_001892038.1 CDS FTM_1428 NC_010677.1 1537500 1538618 R mechanosensitive ion channel protein complement(1537500..1538618) Francisella tularensis subsp. mediasiatica FSC147 6290162 YP_001892039.1 CDS FTM_1429 NC_010677.1 1538644 1539324 R membrane protein complement(1538644..1539324) Francisella tularensis subsp. mediasiatica FSC147 6290129 YP_001892040.1 CDS accC NC_010677.1 1539418 1540773 R acetyl-CoA carboxylase, biotin carboxylase subunit complement(1539418..1540773) Francisella tularensis subsp. mediasiatica FSC147 6291013 YP_001892041.1 CDS accB NC_010677.1 1540838 1541311 R acetyl-CoA carboxylase, biotin carboxy carrier protein subunit complement(1540838..1541311) Francisella tularensis subsp. mediasiatica FSC147 6291596 YP_001892042.1 CDS aroD NC_010677.1 1541316 1541753 R catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase complement(1541316..1541753) Francisella tularensis subsp. mediasiatica FSC147 6291111 YP_001892043.1 CDS apaH NC_010677.1 1541757 1542584 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(1541757..1542584) Francisella tularensis subsp. mediasiatica FSC147 6290199 YP_001892044.1 CDS ksgA NC_010677.1 1542596 1543384 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(1542596..1543384) Francisella tularensis subsp. mediasiatica FSC147 6290156 YP_001892045.1 CDS FTM_1435 NC_010677.1 1543386 1544795 R peptidyl-prolyl cis-trans isomerase complement(1543386..1544795) Francisella tularensis subsp. mediasiatica FSC147 6290433 YP_001892046.1 CDS ostA1 NC_010677.1 1544795 1547398 R organic solvent tolerance protein complement(1544795..1547398) Francisella tularensis subsp. mediasiatica FSC147 6291232 YP_001892047.1 CDS argS NC_010677.1 1547525 1549270 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1547525..1549270 Francisella tularensis subsp. mediasiatica FSC147 6290729 YP_001892048.1 CDS FTM_1438 NC_010677.1 1549311 1549691 R hypothetical protein complement(1549311..1549691) Francisella tularensis subsp. mediasiatica FSC147 6290301 YP_001892049.1 CDS FTM_1440 NC_010677.1 1551403 1551870 R RNA methyltransferase, SpoU family complement(1551403..1551870) Francisella tularensis subsp. mediasiatica FSC147 6290244 YP_001892050.1 CDS hemB NC_010677.1 1551874 1552848 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(1551874..1552848) Francisella tularensis subsp. mediasiatica FSC147 6290032 YP_001892051.1 CDS yhbY NC_010677.1 1552856 1553134 R RNA-binding protein complement(1552856..1553134) Francisella tularensis subsp. mediasiatica FSC147 6290420 YP_001892052.1 CDS holB NC_010677.1 1553145 1554056 R DNA polymerase III, delta prime subunit complement(1553145..1554056) Francisella tularensis subsp. mediasiatica FSC147 6290085 YP_001892053.1 CDS sohB NC_010677.1 1554064 1555080 R SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease complement(1554064..1555080) Francisella tularensis subsp. mediasiatica FSC147 6290073 YP_001892054.1 CDS sspA NC_010677.1 1555092 1555724 R stringent starvation protein A complement(1555092..1555724) Francisella tularensis subsp. mediasiatica FSC147 6291085 YP_001892055.1 CDS FTM_1446 NC_010677.1 1555805 1556119 D hypothetical protein 1555805..1556119 Francisella tularensis subsp. mediasiatica FSC147 6291344 YP_001892056.1 CDS FTM_1447 NC_010677.1 1556140 1556403 D hypothetical protein 1556140..1556403 Francisella tularensis subsp. mediasiatica FSC147 6290304 YP_001892057.1 CDS FTM_1448 NC_010677.1 1556495 1558258 D dolichyl-phosphate-mannose-protein mannosyltransferase family protein 1556495..1558258 Francisella tularensis subsp. mediasiatica FSC147 6290967 YP_001892058.1 CDS FTM_1449 NC_010677.1 1558650 1559606 R glycosyltransferase complement(1558650..1559606) Francisella tularensis subsp. mediasiatica FSC147 6291021 YP_001892059.1 CDS FTM_1450 NC_010677.1 1559705 1560511 D hypothetical protein 1559705..1560511 Francisella tularensis subsp. mediasiatica FSC147 6290096 YP_001892060.1 CDS ftsW NC_010677.1 1560519 1561724 R cell division protein FtsW complement(1560519..1561724) Francisella tularensis subsp. mediasiatica FSC147 6290870 YP_001892061.1 CDS murD NC_010677.1 1561734 1562984 R UDP-N-acetylmuramoylalanine--D-glutamate ligase complement(1561734..1562984) Francisella tularensis subsp. mediasiatica FSC147 6290878 YP_001892062.1 CDS mraY NC_010677.1 1562984 1564081 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(1562984..1564081) Francisella tularensis subsp. mediasiatica FSC147 6290908 YP_001892063.1 CDS pckA NC_010677.1 1564156 1565748 R PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase complement(1564156..1565748) Francisella tularensis subsp. mediasiatica FSC147 6290917 YP_001892064.1 CDS glnS NC_010677.1 1565893 1567539 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 1565893..1567539 Francisella tularensis subsp. mediasiatica FSC147 6290925 YP_001892065.1 CDS yjjK NC_010677.1 1570527 1572368 R drug resistance ATPase-1 family protein complement(1570527..1572368) Francisella tularensis subsp. mediasiatica FSC147 6290960 YP_001892066.1 CDS FTM_1459 NC_010677.1 1572402 1573628 R drug:H+ antiporter-1 (DHA1) family protein complement(1572402..1573628) Francisella tularensis subsp. mediasiatica FSC147 6290962 YP_001892067.1 CDS FTM_1460 NC_010677.1 1573711 1574754 R hypothetical protein complement(1573711..1574754) Francisella tularensis subsp. mediasiatica FSC147 6290979 YP_001892068.1 CDS FTM_1462 NC_010677.1 1576220 1576801 D hypothetical protein 1576220..1576801 Francisella tularensis subsp. mediasiatica FSC147 6291046 YP_001892069.1 CDS FTM_1464 NC_010677.1 1577876 1578391 R acetyltransferase complement(1577876..1578391) Francisella tularensis subsp. mediasiatica FSC147 6291055 YP_001892070.1 CDS FTM_1465 NC_010677.1 1578396 1579112 R hypothetical protein complement(1578396..1579112) Francisella tularensis subsp. mediasiatica FSC147 6291057 YP_001892071.1 CDS rhtB NC_010677.1 1579881 1580516 D homoserine/threonine efflux family protein 1579881..1580516 Francisella tularensis subsp. mediasiatica FSC147 6291104 YP_001892072.1 CDS ppnK NC_010677.1 1580513 1581403 R NAD kinase complement(1580513..1581403) Francisella tularensis subsp. mediasiatica FSC147 6291128 YP_001892073.1 CDS gtrB NC_010677.1 1581591 1582535 D glycosyl transferase family protein 1581591..1582535 Francisella tularensis subsp. mediasiatica FSC147 6291207 YP_001892074.1 CDS FTM_1470 NC_010677.1 1582539 1583318 R ATP-binding cassette (ABC) superfamily protein complement(1582539..1583318) Francisella tularensis subsp. mediasiatica FSC147 6291212 YP_001892075.1 CDS FTM_1471 NC_010677.1 1583327 1584250 R ATP-binding cassette (ABC) superfamily protein complement(1583327..1584250) Francisella tularensis subsp. mediasiatica FSC147 6291219 YP_001892076.1 CDS FTM_1472 NC_010677.1 1585213 1585989 R hypothetical protein complement(1585213..1585989) Francisella tularensis subsp. mediasiatica FSC147 6291228 YP_001892077.1 CDS FTM_1473 NC_010677.1 1586439 1587206 R Mg-dependent DNase complement(1586439..1587206) Francisella tularensis subsp. mediasiatica FSC147 6291238 YP_001892078.1 CDS bfr NC_010677.1 1588919 1589359 D bacterioferritin 1588919..1589359 Francisella tularensis subsp. mediasiatica FSC147 6291257 YP_001892079.1 CDS FTM_1477 NC_010677.1 1589977 1590933 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(1589977..1590933) Francisella tularensis subsp. mediasiatica FSC147 6291285 YP_001892080.1 CDS ppx NC_010677.1 1592487 1593413 R exopolyphosphatase complement(1592487..1593413) Francisella tularensis subsp. mediasiatica FSC147 6290330 YP_001892081.1 CDS trxA1 NC_010677.1 1593611 1593934 D thioredoxin 1593611..1593934 Francisella tularensis subsp. mediasiatica FSC147 6291332 YP_001892082.1 CDS rho NC_010677.1 1593977 1595239 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1593977..1595239 Francisella tularensis subsp. mediasiatica FSC147 6291339 YP_001892083.1 CDS manB NC_010677.1 1596356 1597840 R phosphomannomutase complement(1596356..1597840) Francisella tularensis subsp. mediasiatica FSC147 6291357 YP_001892084.1 CDS manC NC_010677.1 1597871 1599277 R mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase complement(1597871..1599277) Francisella tularensis subsp. mediasiatica FSC147 6291382 YP_001892085.1 CDS wbtM NC_010677.1 1600425 1601474 R dTDP-glucose 4,6-dehydratase complement(1600425..1601474) Francisella tularensis subsp. mediasiatica FSC147 6291391 YP_001892086.1 CDS wbtL NC_010677.1 1601992 1602876 R glucose-1-phosphate thymidylyltransferase complement(1601992..1602876) Francisella tularensis subsp. mediasiatica FSC147 6291392 YP_001892087.1 CDS wbtK NC_010677.1 1602901 1603761 R glycosyltransferase complement(1602901..1603761) Francisella tularensis subsp. mediasiatica FSC147 6291444 YP_001892088.1 CDS wzx NC_010677.1 1603754 1605241 R O-antigen flippase complement(1603754..1605241) Francisella tularensis subsp. mediasiatica FSC147 6291478 YP_001892089.1 CDS wbtJ NC_010677.1 1605246 1605971 R hypothetical protein complement(1605246..1605971) Francisella tularensis subsp. mediasiatica FSC147 6291483 YP_001892090.1 CDS wbtI NC_010677.1 1605968 1607050 R sugar transamine/perosamine synthetase complement(1605968..1607050) Francisella tularensis subsp. mediasiatica FSC147 6291496 YP_001892091.1 CDS wbtH NC_010677.1 1607043 1608929 R glutamine amidotransferase/asparagine synthase complement(1607043..1608929) Francisella tularensis subsp. mediasiatica FSC147 6291511 YP_001892092.1 CDS wbtG NC_010677.1 1608929 1610029 R glycosyl transferase family protein complement(1608929..1610029) Francisella tularensis subsp. mediasiatica FSC147 6291513 YP_001892093.1 CDS wzy NC_010677.1 1610026 1611255 R membrane protein/O-antigen protein complement(1610026..1611255) Francisella tularensis subsp. mediasiatica FSC147 6291519 YP_001892094.1 CDS wbtF NC_010677.1 1611276 1612247 R NAD dependent epimerase complement(1611276..1612247) Francisella tularensis subsp. mediasiatica FSC147 6291520 YP_001892095.1 CDS wbtE NC_010677.1 1612247 1613557 R UDP-glucose/GDP-mannose dehydrogenase complement(1612247..1613557) Francisella tularensis subsp. mediasiatica FSC147 6291526 YP_001892096.1 CDS wbtD NC_010677.1 1613575 1614666 R group 1 glycosyl transferase complement(1613575..1614666) Francisella tularensis subsp. mediasiatica FSC147 6291527 YP_001892097.1 CDS wbtC NC_010677.1 1614656 1615447 R UDP-glucose 4-epimerase complement(1614656..1615447) Francisella tularensis subsp. mediasiatica FSC147 6291533 YP_001892098.1 CDS wbtB NC_010677.1 1615449 1616081 R galactosyl transferase complement(1615449..1616081) Francisella tularensis subsp. mediasiatica FSC147 6291534 YP_001892099.1 CDS wbtA NC_010677.1 1616074 1617810 R dTDP-glucose 4,6-dehydratase complement(1616074..1617810) Francisella tularensis subsp. mediasiatica FSC147 6291549 YP_001892100.1 CDS gdhA NC_010677.1 1618968 1620317 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1618968..1620317 Francisella tularensis subsp. mediasiatica FSC147 6291555 YP_001892101.1 CDS FTM_1500 NC_010677.1 1622357 1623322 R hypothetical protein complement(1622357..1623322) Francisella tularensis subsp. mediasiatica FSC147 6291566 YP_001892102.1 CDS rplQ NC_010677.1 1625146 1625583 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(1625146..1625583) Francisella tularensis subsp. mediasiatica FSC147 6291576 YP_001892103.1 CDS rpoA NC_010677.1 1625628 1626599 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(1625628..1626599) Francisella tularensis subsp. mediasiatica FSC147 6291582 YP_001892104.1 CDS rpsD NC_010677.1 1626657 1627277 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(1626657..1627277) Francisella tularensis subsp. mediasiatica FSC147 6291590 YP_001892105.1 CDS rpsK NC_010677.1 1627299 1627688 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(1627299..1627688) Francisella tularensis subsp. mediasiatica FSC147 6291606 YP_001892106.1 CDS rpsM NC_010677.1 1627727 1628083 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(1627727..1628083) Francisella tularensis subsp. mediasiatica FSC147 6291612 YP_001892107.1 CDS rpmJ NC_010677.1 1628200 1628313 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(1628200..1628313) Francisella tularensis subsp. mediasiatica FSC147 6291617 YP_001892108.1 CDS secY NC_010677.1 1628337 1629662 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(1628337..1629662) Francisella tularensis subsp. mediasiatica FSC147 6291623 YP_001892109.1 CDS rplO NC_010677.1 1629673 1630104 R late assembly protein; 50S ribosomal protein L15 complement(1629673..1630104) Francisella tularensis subsp. mediasiatica FSC147 6291625 YP_001892110.1 CDS rpmD NC_010677.1 1630111 1630296 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(1630111..1630296) Francisella tularensis subsp. mediasiatica FSC147 6291628 YP_001892111.1 CDS rpsE NC_010677.1 1630303 1630803 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(1630303..1630803) Francisella tularensis subsp. mediasiatica FSC147 6291630 YP_001892112.1 CDS rplR NC_010677.1 1630831 1631184 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(1630831..1631184) Francisella tularensis subsp. mediasiatica FSC147 6291640 YP_001892113.1 CDS rplF NC_010677.1 1631207 1631743 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(1631207..1631743) Francisella tularensis subsp. mediasiatica FSC147 6291650 YP_001892114.1 CDS rpsH NC_010677.1 1631762 1632160 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(1631762..1632160) Francisella tularensis subsp. mediasiatica FSC147 6291654 YP_001892115.1 CDS rpsN NC_010677.1 1632177 1632482 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(1632177..1632482) Francisella tularensis subsp. mediasiatica FSC147 6291660 YP_001892116.1 CDS rplE NC_010677.1 1632501 1633040 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(1632501..1633040) Francisella tularensis subsp. mediasiatica FSC147 6291664 YP_001892117.1 CDS rplX NC_010677.1 1633052 1633369 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(1633052..1633369) Francisella tularensis subsp. mediasiatica FSC147 6291676 YP_001892118.1 CDS rplN NC_010677.1 1633391 1633759 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(1633391..1633759) Francisella tularensis subsp. mediasiatica FSC147 6291701 YP_001892119.1 CDS rpsQ NC_010677.1 1633850 1634101 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(1633850..1634101) Francisella tularensis subsp. mediasiatica FSC147 6290417 YP_001892120.1 CDS rpmC NC_010677.1 1634114 1634314 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(1634114..1634314) Francisella tularensis subsp. mediasiatica FSC147 6290207 YP_001892121.1 CDS rplP NC_010677.1 1634314 1634727 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(1634314..1634727) Francisella tularensis subsp. mediasiatica FSC147 6290902 YP_001892122.1 CDS rpsC NC_010677.1 1634727 1635398 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(1634727..1635398) Francisella tularensis subsp. mediasiatica FSC147 6291291 YP_001892123.1 CDS rplV NC_010677.1 1635413 1635748 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(1635413..1635748) Francisella tularensis subsp. mediasiatica FSC147 6291366 YP_001892124.1 CDS rpsS NC_010677.1 1635764 1636042 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(1635764..1636042) Francisella tularensis subsp. mediasiatica FSC147 6291156 YP_001892125.1 CDS rplB NC_010677.1 1636057 1636881 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(1636057..1636881) Francisella tularensis subsp. mediasiatica FSC147 6290241 YP_001892126.1 CDS rplW NC_010677.1 1636903 1637202 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(1636903..1637202) Francisella tularensis subsp. mediasiatica FSC147 6290570 YP_001892127.1 CDS rplD NC_010677.1 1637199 1637822 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(1637199..1637822) Francisella tularensis subsp. mediasiatica FSC147 6291041 YP_001892128.1 CDS rplC NC_010677.1 1637855 1638487 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(1637855..1638487) Francisella tularensis subsp. mediasiatica FSC147 6290579 YP_001892129.1 CDS rpsJ NC_010677.1 1638591 1638908 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(1638591..1638908) Francisella tularensis subsp. mediasiatica FSC147 6290336 YP_001892130.1 CDS fusA NC_010677.1 1638929 1641043 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(1638929..1641043) Francisella tularensis subsp. mediasiatica FSC147 6290952 YP_001892131.1 CDS rpsG NC_010677.1 1641058 1641531 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(1641058..1641531) Francisella tularensis subsp. mediasiatica FSC147 6290961 YP_001892132.1 CDS rpsL NC_010677.1 1641570 1641944 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(1641570..1641944) Francisella tularensis subsp. mediasiatica FSC147 6290872 YP_001892133.1 CDS pgsA NC_010677.1 1642079 1642675 R phosphatidylglycerophosphate synthetase complement(1642079..1642675) Francisella tularensis subsp. mediasiatica FSC147 6291610 YP_001892134.1 CDS dut NC_010677.1 1642679 1643125 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(1642679..1643125) Francisella tularensis subsp. mediasiatica FSC147 6291558 YP_001892135.1 CDS cdsA NC_010677.1 1643135 1643929 R phosphatidate cytidylyltransferase complement(1643135..1643929) Francisella tularensis subsp. mediasiatica FSC147 6291409 YP_001892136.1 CDS uppS NC_010677.1 1643943 1644665 R catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase complement(1643943..1644665) Francisella tularensis subsp. mediasiatica FSC147 6291512 YP_001892137.1 CDS frr NC_010677.1 1644749 1645306 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(1644749..1645306) Francisella tularensis subsp. mediasiatica FSC147 6291475 YP_001892138.1 CDS pyrH NC_010677.1 1645335 1646084 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(1645335..1646084) Francisella tularensis subsp. mediasiatica FSC147 6291456 YP_001892139.1 CDS tsf NC_010677.1 1646088 1646957 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(1646088..1646957) Francisella tularensis subsp. mediasiatica FSC147 6291044 YP_001892140.1 CDS rpsB NC_010677.1 1646979 1647698 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(1646979..1647698) Francisella tularensis subsp. mediasiatica FSC147 6291277 YP_001892141.1 CDS folA NC_010677.1 1647890 1648432 D dihydrofolate reductase 1647890..1648432 Francisella tularensis subsp. mediasiatica FSC147 6290986 YP_001892142.1 CDS FTM_1541 NC_010677.1 1648514 1649437 D hypothetical protein 1648514..1649437 Francisella tularensis subsp. mediasiatica FSC147 6291038 YP_001892143.1 CDS FTM_1544 NC_010677.1 1652284 1653252 R hypothetical protein complement(1652284..1653252) Francisella tularensis subsp. mediasiatica FSC147 6291042 YP_001892144.1 CDS gltX NC_010677.1 1653252 1654658 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(1653252..1654658) Francisella tularensis subsp. mediasiatica FSC147 6291039 YP_001892145.1 CDS fumC NC_010677.1 1654788 1656179 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1654788..1656179) Francisella tularensis subsp. mediasiatica FSC147 6291137 YP_001892146.1 CDS nfnB NC_010677.1 1656868 1657521 D catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 1656868..1657521 Francisella tularensis subsp. mediasiatica FSC147 6291066 YP_001892147.1 CDS FTM_1549 NC_010677.1 1657548 1658705 D L-lactate dehydrogenase 1657548..1658705 Francisella tularensis subsp. mediasiatica FSC147 6291598 YP_001892148.1 CDS FTM_1550 NC_010677.1 1658702 1659037 R membrane protein complement(1658702..1659037) Francisella tularensis subsp. mediasiatica FSC147 6290994 YP_001892149.1 CDS FTM_1551 NC_010677.1 1659221 1661023 R hypothetical protein complement(1659221..1661023) Francisella tularensis subsp. mediasiatica FSC147 6291569 YP_001892150.1 CDS valS NC_010677.1 1661052 1663811 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(1661052..1663811) Francisella tularensis subsp. mediasiatica FSC147 6290982 YP_001892151.1 CDS holC NC_010677.1 1663943 1664383 R DNA polymerase III subunit chi complement(1663943..1664383) Francisella tularensis subsp. mediasiatica FSC147 6291019 YP_001892152.1 CDS FTM_1554 NC_010677.1 1664414 1664896 R membrane protein complement(1664414..1664896) Francisella tularensis subsp. mediasiatica FSC147 6291082 YP_001892153.1 CDS pcp NC_010677.1 1664904 1665572 R pyrrolidone carboxylylate peptidase complement(1664904..1665572) Francisella tularensis subsp. mediasiatica FSC147 6291136 YP_001892154.1 CDS FTM_1556 NC_010677.1 1665579 1667204 R hypothetical protein complement(1665579..1667204) Francisella tularensis subsp. mediasiatica FSC147 6291063 YP_001892155.1 CDS FTM_1557 NC_010677.1 1667194 1668027 R hypothetical protein complement(1667194..1668027) Francisella tularensis subsp. mediasiatica FSC147 6290884 YP_001892156.1 CDS FTM_1558 NC_010677.1 1668018 1669016 R membrane protein with von Willebrand factor type A domain complement(1668018..1669016) Francisella tularensis subsp. mediasiatica FSC147 6291359 YP_001892157.1 CDS FTM_1559 NC_010677.1 1669018 1670019 R hypothetical protein complement(1669018..1670019) Francisella tularensis subsp. mediasiatica FSC147 6291307 YP_001892158.1 CDS FTM_1560 NC_010677.1 1670016 1670492 R hypothetical protein complement(1670016..1670492) Francisella tularensis subsp. mediasiatica FSC147 6291491 YP_001892159.1 CDS FTM_1561 NC_010677.1 1670482 1671393 R hypothetical protein complement(1670482..1671393) Francisella tularensis subsp. mediasiatica FSC147 6291574 YP_001892160.1 CDS FTM_1562 NC_010677.1 1671406 1672362 R MoxR-like ATPase complement(1671406..1672362) Francisella tularensis subsp. mediasiatica FSC147 6291490 YP_001892161.1 CDS FTM_1563 NC_010677.1 1672508 1672942 D lipoprotein 1672508..1672942 Francisella tularensis subsp. mediasiatica FSC147 6291561 YP_001892162.1 CDS pdxY NC_010677.1 1672949 1673800 D pyridoxal kinase 1672949..1673800 Francisella tularensis subsp. mediasiatica FSC147 6291431 YP_001892163.1 CDS FTM_1565 NC_010677.1 1673800 1674495 D hypothetical protein 1673800..1674495 Francisella tularensis subsp. mediasiatica FSC147 6291415 YP_001892164.1 CDS lpxD2 NC_010677.1 1674570 1675613 D UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 1674570..1675613 Francisella tularensis subsp. mediasiatica FSC147 6291236 YP_001892165.1 CDS cyoE NC_010677.1 1675758 1676606 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(1675758..1676606) Francisella tularensis subsp. mediasiatica FSC147 6291231 YP_001892166.1 CDS cyoD NC_010677.1 1676637 1676969 R cytochrome bo terminal oxidase subunit IV complement(1676637..1676969) Francisella tularensis subsp. mediasiatica FSC147 6291246 YP_001892167.1 CDS cyoC NC_010677.1 1676971 1677573 R cytochrome bo terminal oxidase subunit III complement(1676971..1677573) Francisella tularensis subsp. mediasiatica FSC147 6290974 YP_001892168.1 CDS cyoB NC_010677.1 1677570 1679600 R cytochrome bo terminal oxidase subunit I complement(1677570..1679600) Francisella tularensis subsp. mediasiatica FSC147 6290359 YP_001892169.1 CDS cyoA NC_010677.1 1679639 1680541 R cytochrome bo terminal oxidase subunit II complement(1679639..1680541) Francisella tularensis subsp. mediasiatica FSC147 6291622 YP_001892170.1 CDS FTM_1572 NC_010677.1 1680901 1682268 D major facilitator superfamily (MFS) transport protein 1680901..1682268 Francisella tularensis subsp. mediasiatica FSC147 6291459 YP_001892171.1 CDS cydA NC_010677.1 1682722 1684476 D cytochrome bd-I terminal oxidase subunit I 1682722..1684476 Francisella tularensis subsp. mediasiatica FSC147 6291609 YP_001892172.1 CDS cydB NC_010677.1 1684487 1685680 D cytochrome bd-I terminal oxidase subunit II 1684487..1685680 Francisella tularensis subsp. mediasiatica FSC147 6291381 YP_001892173.1 CDS FTM_1575 NC_010677.1 1685913 1686611 D polar amino acid uptake transporter 1685913..1686611 Francisella tularensis subsp. mediasiatica FSC147 6291530 YP_001892174.1 CDS FTM_1578 NC_010677.1 1690304 1691272 R hypothetical protein complement(1690304..1691272) Francisella tularensis subsp. mediasiatica FSC147 6291302 YP_001892175.1 CDS FTM_1579 NC_010677.1 1691462 1693318 D ribonuclease II family protein 1691462..1693318 Francisella tularensis subsp. mediasiatica FSC147 6291120 YP_001892176.1 CDS FTM_1580 NC_010677.1 1693664 1694317 D acarboxylesterase/phospholipase family protein 1693664..1694317 Francisella tularensis subsp. mediasiatica FSC147 6291176 YP_001892177.1 CDS hemC NC_010677.1 1694314 1695216 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 1694314..1695216 Francisella tularensis subsp. mediasiatica FSC147 6291143 YP_001892178.1 CDS crcB NC_010677.1 1695217 1695609 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1695217..1695609 Francisella tularensis subsp. mediasiatica FSC147 6291211 YP_001892179.1 CDS FTM_1583 NC_010677.1 1695606 1696013 D membrane protein 1695606..1696013 Francisella tularensis subsp. mediasiatica FSC147 6290901 YP_001892180.1 CDS FTM_1584 NC_010677.1 1696156 1696725 D membrane protein 1696156..1696725 Francisella tularensis subsp. mediasiatica FSC147 6291107 YP_001892181.1 CDS FTM_1585 NC_010677.1 1696722 1696895 R hypothetical protein complement(1696722..1696895) Francisella tularensis subsp. mediasiatica FSC147 6291091 YP_001892182.1 CDS FTM_1586 NC_010677.1 1697025 1698824 D anion ABC transporter permease 1697025..1698824 Francisella tularensis subsp. mediasiatica FSC147 6290897 YP_001892183.1 CDS FTM_1587 NC_010677.1 1698843 1700159 D ABC transporter ATP-binding protein 1698843..1700159 Francisella tularensis subsp. mediasiatica FSC147 6291584 YP_001892184.1 CDS FTM_1589 NC_010677.1 1701872 1703758 D monovalent cation:proton antiporter 1701872..1703758 Francisella tularensis subsp. mediasiatica FSC147 6291495 YP_001892185.1 CDS paaY NC_010677.1 1703743 1704282 D carbonic anhydrase/acetyltransferase 1703743..1704282 Francisella tularensis subsp. mediasiatica FSC147 6291557 YP_001892186.1 CDS lolB NC_010677.1 1704233 1704877 D outer membrane lipoprotein LolB 1704233..1704877 Francisella tularensis subsp. mediasiatica FSC147 6291517 YP_001892187.1 CDS ipk NC_010677.1 1704865 1705692 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1704865..1705692 Francisella tularensis subsp. mediasiatica FSC147 6291342 YP_001892188.1 CDS FTM_1596 NC_010677.1 1707223 1707738 R cytochrome b561 family protein complement(1707223..1707738) Francisella tularensis subsp. mediasiatica FSC147 6290932 YP_001892189.1 CDS FTM_1597 NC_010677.1 1707819 1708814 R inorganic phosphate transporter (PiT) family protein complement(1707819..1708814) Francisella tularensis subsp. mediasiatica FSC147 6290930 YP_001892190.1 CDS FTM_1598 NC_010677.1 1708832 1709488 R hypothetical protein complement(1708832..1709488) Francisella tularensis subsp. mediasiatica FSC147 6290905 YP_001892191.1 CDS FTM_1599 NC_010677.1 1709725 1711269 D acid phosphatase 1709725..1711269 Francisella tularensis subsp. mediasiatica FSC147 6291351 YP_001892192.1 CDS uspA NC_010677.1 1715402 1716238 R universal stress protein complement(1715402..1716238) Francisella tularensis subsp. mediasiatica FSC147 6291518 YP_001892193.1 CDS FTM_1605 NC_010677.1 1716314 1719055 R DNA/RNA helicase complement(1716314..1719055) Francisella tularensis subsp. mediasiatica FSC147 6291541 YP_001892194.1 CDS FTM_1606 NC_010677.1 1719039 1719818 R hypothetical protein complement(1719039..1719818) Francisella tularensis subsp. mediasiatica FSC147 6291484 YP_001892195.1 CDS FTM_1607 NC_010677.1 1719891 1720454 R HAD superfamily hydrolase complement(1719891..1720454) Francisella tularensis subsp. mediasiatica FSC147 6291109 YP_001892196.1 CDS FTM_1609 NC_010677.1 1721277 1722149 R SAM-dependent methyltransferase complement(1721277..1722149) Francisella tularensis subsp. mediasiatica FSC147 6291580 YP_001892197.1 CDS murC NC_010677.1 1722142 1723497 R UDP-N-acetylmuramate-alanine ligase complement(1722142..1723497) Francisella tularensis subsp. mediasiatica FSC147 6291047 YP_001892198.1 CDS FTM_1611 NC_010677.1 1723564 1724337 R shikimate 5-dehydrogenase complement(1723564..1724337) Francisella tularensis subsp. mediasiatica FSC147 6291011 YP_001892199.1 CDS FTM_1612 NC_010677.1 1724464 1724922 D hypothetical protein 1724464..1724922 Francisella tularensis subsp. mediasiatica FSC147 6291348 YP_001892200.1 CDS rpmH NC_010677.1 1725014 1725148 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1725014..1725148 Francisella tularensis subsp. mediasiatica FSC147 6291103 YP_001892201.1 CDS rnpA NC_010677.1 1725138 1725491 D ribonuclease P protein component 1725138..1725491 Francisella tularensis subsp. mediasiatica FSC147 6291240 YP_001892202.1 CDS FTM_1615 NC_010677.1 1725467 1725715 D hypothetical protein 1725467..1725715 Francisella tularensis subsp. mediasiatica FSC147 6291435 YP_001892203.1 CDS FTM_1616 NC_010677.1 1725724 1727379 D membrane protein 1725724..1727379 Francisella tularensis subsp. mediasiatica FSC147 6291680 YP_001892204.1 CDS FTM_1617 NC_010677.1 1727386 1728285 D LPS fatty acid acyltransferase 1727386..1728285 Francisella tularensis subsp. mediasiatica FSC147 6291539 YP_001892205.1 CDS FTM_1618 NC_010677.1 1728346 1729269 D LPS fatty acid acyltransferase 1728346..1729269 Francisella tularensis subsp. mediasiatica FSC147 6291427 YP_001892206.1 CDS pilE NC_010677.1 1729281 1729688 D Type IV pili, pilus assembly protein 1729281..1729688 Francisella tularensis subsp. mediasiatica FSC147 6291311 YP_001892207.1 CDS efp NC_010677.1 1729728 1730297 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1729728..1730297 Francisella tularensis subsp. mediasiatica FSC147 6291621 YP_001892208.1 CDS orn NC_010677.1 1730300 1730836 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1730300..1730836 Francisella tularensis subsp. mediasiatica FSC147 6291428 YP_001892209.1 CDS ppdK NC_010677.1 1734512 1737145 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase complement(1734512..1737145) Francisella tularensis subsp. mediasiatica FSC147 6291271 YP_001892210.1 CDS feoB NC_010677.1 1737972 1740215 R ferrous iron transport protein B complement(1737972..1740215) Francisella tularensis subsp. mediasiatica FSC147 6291269 YP_001892211.1 CDS priA NC_010677.1 1741641 1743794 R primosomal protein N' complement(1741641..1743794) Francisella tularensis subsp. mediasiatica FSC147 6291364 YP_001892212.1 CDS FTM_1629 NC_010677.1 1743791 1744366 R nicotinamide ribonucleoside (NR) uptake permease (PnuC) family protein complement(1743791..1744366) Francisella tularensis subsp. mediasiatica FSC147 6291386 YP_001892213.1 CDS rbn NC_010677.1 1744385 1745572 R tRNA processing ribonuclease BN complement(1744385..1745572) Francisella tularensis subsp. mediasiatica FSC147 6291305 YP_001892214.1 CDS wrbA NC_010677.1 1745579 1746175 D trp repressor binding protein 1745579..1746175 Francisella tularensis subsp. mediasiatica FSC147 6291299 YP_001892215.1 CDS FTM_1632 NC_010677.1 1746186 1746650 D outer membrane lipoprotein 1746186..1746650 Francisella tularensis subsp. mediasiatica FSC147 6291032 YP_001892216.1 CDS FTM_1633 NC_010677.1 1746771 1747994 D major facilitator superfamily (MFS) transport protein 1746771..1747994 Francisella tularensis subsp. mediasiatica FSC147 6291027 YP_001892217.1 CDS FTM_1634 NC_010677.1 1748069 1748986 D manganese/Zinc/Iron chelate uptake transporter family protein 1748069..1748986 Francisella tularensis subsp. mediasiatica FSC147 6291135 YP_001892218.1 CDS FTM_1635 NC_010677.1 1748987 1749664 D ATP-binding cassette (ABC) superfamily protein 1748987..1749664 Francisella tularensis subsp. mediasiatica FSC147 6291589 YP_001892219.1 CDS FTM_1636 NC_010677.1 1749606 1750448 D manganese/zinc/iron chelate uptake transporter (MZT) family protein 1749606..1750448 Francisella tularensis subsp. mediasiatica FSC147 6291548 YP_001892220.1 CDS hpt NC_010677.1 1751270 1751803 R hypoxanthine-guanine phosphoribosyltransferase complement(1751270..1751803) Francisella tularensis subsp. mediasiatica FSC147 6291362 YP_001892221.1 CDS purA NC_010677.1 1751807 1753093 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(1751807..1753093) Francisella tularensis subsp. mediasiatica FSC147 6291343 YP_001892222.1 CDS purH NC_010677.1 1753270 1754817 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1753270..1754817 Francisella tularensis subsp. mediasiatica FSC147 6291023 YP_001892223.1 CDS blc NC_010677.1 1758946 1759464 R outer membrane lipoprotein blc complement(1758946..1759464) Francisella tularensis subsp. mediasiatica FSC147 6291270 YP_001892224.1 CDS holA NC_010677.1 1759550 1760527 D DNA polymerase III subunit delta 1759550..1760527 Francisella tularensis subsp. mediasiatica FSC147 6291125 YP_001892225.1 CDS glnA NC_010677.1 1760647 1761684 D glutamine synthetase 1760647..1761684 Francisella tularensis subsp. mediasiatica FSC147 6290781 YP_001892226.1 CDS FTM_1648 NC_010677.1 1764285 1764827 D hypothetical protein 1764285..1764827 Francisella tularensis subsp. mediasiatica FSC147 6291361 YP_001892227.1 CDS lysU NC_010677.1 1765212 1766942 R lysyl-tRNA synthetase complement(1765212..1766942) Francisella tularensis subsp. mediasiatica FSC147 6291121 YP_001892228.1 CDS prfB NC_010677.1 1767075 1768052 R peptide chain release factor 2 complement(1767075..1768052) Francisella tularensis subsp. mediasiatica FSC147 6291286 YP_001892229.1 CDS dnaX NC_010677.1 1768325 1769965 D DNA polymerase III subunit gamma/tau 1768325..1769965 Francisella tularensis subsp. mediasiatica FSC147 6291061 YP_001892230.1 CDS lpxC NC_010677.1 1769980 1770837 R zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase complement(1769980..1770837) Francisella tularensis subsp. mediasiatica FSC147 6290998 YP_001892231.1 CDS ftsZ NC_010677.1 1770863 1772008 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(1770863..1772008) Francisella tularensis subsp. mediasiatica FSC147 6290950 YP_001892232.1 CDS ftsA NC_010677.1 1772052 1773314 R cell division protein FtsA complement(1772052..1773314) Francisella tularensis subsp. mediasiatica FSC147 6291130 YP_001892233.1 CDS ftsQ NC_010677.1 1773416 1774099 R cell division protein FtsQ complement(1773416..1774099) Francisella tularensis subsp. mediasiatica FSC147 6291634 YP_001892234.1 CDS FTM_1657 NC_010677.1 1774991 1775452 R zinc-binding protein complement(1774991..1775452) Francisella tularensis subsp. mediasiatica FSC147 6290978 YP_001892235.1 CDS rpsA NC_010677.1 1775600 1777270 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1775600..1777270 Francisella tularensis subsp. mediasiatica FSC147 6291096 YP_001892236.1 CDS FTM_1659 NC_010677.1 1777387 1777929 D Sua5/YciO/YrdC family protein 1777387..1777929 Francisella tularensis subsp. mediasiatica FSC147 6291105 YP_001892237.1 CDS FTM_1660 NC_010677.1 1778027 1778563 D hypothetical protein 1778027..1778563 Francisella tularensis subsp. mediasiatica FSC147 6291319 YP_001892238.1 CDS plsC NC_010677.1 1778960 1779850 R putative acyltransferase complement(1778960..1779850) Francisella tularensis subsp. mediasiatica FSC147 6291316 YP_001892239.1 CDS rimK NC_010677.1 1782121 1783590 D glutathione synthase/ribosomal protein S6 modification protein 1782121..1783590 Francisella tularensis subsp. mediasiatica FSC147 6291353 YP_001892240.1 CDS FTM_1666 NC_010677.1 1785177 1785959 D nitrate/sulfonate/bicarbonate ABC transporter ATPase 1785177..1785959 Francisella tularensis subsp. mediasiatica FSC147 6291262 YP_001892241.1 CDS FTM_1667 NC_010677.1 1785953 1786522 R YggT family membrane protein complement(1785953..1786522) Francisella tularensis subsp. mediasiatica FSC147 6291260 YP_001892242.1 CDS purL NC_010677.1 1789187 1793059 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(1789187..1793059) Francisella tularensis subsp. mediasiatica FSC147 6291313 YP_001892243.1 CDS purF NC_010677.1 1793059 1794549 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(1793059..1794549) Francisella tularensis subsp. mediasiatica FSC147 6291309 YP_001892244.1 CDS FTM_1674 NC_010677.1 1795999 1796640 R phosphopantetheinyl transferase complement(1795999..1796640) Francisella tularensis subsp. mediasiatica FSC147 6291709 YP_001892245.1 CDS tolC NC_010677.1 1796649 1798178 R outer membrane efflux protein, TolC complement(1796649..1798178) Francisella tularensis subsp. mediasiatica FSC147 6290892 YP_001892246.1 CDS pcm NC_010677.1 1798187 1798807 R protein-L-isoaspartate O-methyltransferase complement(1798187..1798807) Francisella tularensis subsp. mediasiatica FSC147 6291088 YP_001892247.1 CDS FTM_1677 NC_010677.1 1799127 1800458 D peptidase U32 family 1799127..1800458 Francisella tularensis subsp. mediasiatica FSC147 6291094 YP_001892248.1 CDS FTM_1678 NC_010677.1 1800499 1801680 R drug:H+ antiporter-1 (DHA1) family protein complement(1800499..1801680) Francisella tularensis subsp. mediasiatica FSC147 6291227 YP_001892249.1 CDS nhaD NC_010677.1 1801855 1803282 D Na+:H+ antiporter, NhaD 1801855..1803282 Francisella tularensis subsp. mediasiatica FSC147 6290874 YP_001892250.1 CDS FTM_1681 NC_010677.1 1804935 1806809 R amino acid-polyamine-organocation (APC) superfamily protein complement(1804935..1806809) Francisella tularensis subsp. mediasiatica FSC147 6291626 YP_001892251.1 CDS obgE NC_010677.1 1806816 1807820 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(1806816..1807820) Francisella tularensis subsp. mediasiatica FSC147 6291502 YP_001892252.1 CDS tyrP NC_010677.1 1807896 1809092 R tyrosine permease complement(1807896..1809092) Francisella tularensis subsp. mediasiatica FSC147 6291349 YP_001892253.1 CDS FTM_1684 NC_010677.1 1809539 1810183 R outer membrane associated protein complement(1809539..1810183) Francisella tularensis subsp. mediasiatica FSC147 6291697 YP_001892254.1 CDS kdpD NC_010677.1 1810963 1813644 R two component regulator, sensor histidine kinase KdpD complement(1810963..1813644) Francisella tularensis subsp. mediasiatica FSC147 6291644 YP_001892255.1 CDS kdpC NC_010677.1 1813748 1814302 R potassium-transporting ATPase C chain complement(1813748..1814302) Francisella tularensis subsp. mediasiatica FSC147 6291524 YP_001892256.1 CDS kdpB NC_010677.1 1814319 1816358 R potassium-transporting ATPase B chain complement(1814319..1816358) Francisella tularensis subsp. mediasiatica FSC147 6291300 YP_001892257.1 CDS kdpA NC_010677.1 1816368 1818089 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(1816368..1818089) Francisella tularensis subsp. mediasiatica FSC147 6291298 YP_001892258.1 CDS pdpA2 NC_010677.1 1825027 1827489 D hypothetical protein 1825027..1827489 Francisella tularensis subsp. mediasiatica FSC147 6291153 YP_001892259.1 CDS pdpB2 NC_010677.1 1827494 1830775 D hypothetical protein 1827494..1830775 Francisella tularensis subsp. mediasiatica FSC147 6291113 YP_001892260.1 CDS FTM_1698 NC_010677.1 1830765 1831142 D lipoprotein 1830765..1831142 Francisella tularensis subsp. mediasiatica FSC147 6291410 YP_001892261.1 CDS FTM_1699 NC_010677.1 1831155 1831649 D hypothetical protein 1831155..1831649 Francisella tularensis subsp. mediasiatica FSC147 6291408 YP_001892262.1 CDS FTM_1700 NC_010677.1 1831654 1833318 D hypothetical protein 1831654..1833318 Francisella tularensis subsp. mediasiatica FSC147 6291074 YP_001892263.1 CDS FTM_1701 NC_010677.1 1833386 1833907 D hypothetical protein 1833386..1833907 Francisella tularensis subsp. mediasiatica FSC147 6291223 YP_001892264.1 CDS FTM_1702 NC_010677.1 1833920 1835350 D hypothetical protein 1833920..1835350 Francisella tularensis subsp. mediasiatica FSC147 6290977 YP_001892265.1 CDS FTM_1703 NC_010677.1 1835363 1835980 D hypothetical protein 1835363..1835980 Francisella tularensis subsp. mediasiatica FSC147 6291383 YP_001892266.1 CDS FTM_1704 NC_010677.1 1836002 1837153 D hypothetical protein 1836002..1837153 Francisella tularensis subsp. mediasiatica FSC147 6291370 YP_001892267.1 CDS FTM_1705 NC_010677.1 1837119 1837892 D hypothetical protein 1837119..1837892 Francisella tularensis subsp. mediasiatica FSC147 6291400 YP_001892268.1 CDS pdpC2 NC_010677.1 1837932 1841918 D PdpC 1837932..1841918 Francisella tularensis subsp. mediasiatica FSC147 6291396 YP_001892269.1 CDS FTM_1707 NC_010677.1 1841936 1842511 D hypothetical protein 1841936..1842511 Francisella tularensis subsp. mediasiatica FSC147 6289989 YP_001892270.1 CDS iglD2 NC_010677.1 1842518 1843714 R intracellular growth locus protein D complement(1842518..1843714) Francisella tularensis subsp. mediasiatica FSC147 6289998 YP_001892271.1 CDS iglC2 NC_010677.1 1843735 1844364 R intracellular growth locus protein C complement(1843735..1844364) Francisella tularensis subsp. mediasiatica FSC147 6290007 YP_001892272.1 CDS iglB2 NC_010677.1 1844381 1845901 R intracellular growth locus protein B complement(1844381..1845901) Francisella tularensis subsp. mediasiatica FSC147 6290009 YP_001892273.1 CDS iglA2 NC_010677.1 1845915 1846469 R intracellular growth locus protein A complement(1845915..1846469) Francisella tularensis subsp. mediasiatica FSC147 6290616 YP_001892274.1 CDS pdpD2 NC_010677.1 1846550 1850281 R hypothetical protein complement(1846550..1850281) Francisella tularensis subsp. mediasiatica FSC147 6290037 YP_001892275.1 CDS FTM_1716 NC_010677.1 1853681 1854889 D metabolite:H+ symporter (MHS) family protein 1853681..1854889 Francisella tularensis subsp. mediasiatica FSC147 6290057 YP_001892276.1 CDS aspS NC_010677.1 1855064 1856842 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1855064..1856842 Francisella tularensis subsp. mediasiatica FSC147 6290066 YP_001892277.1 CDS pta NC_010677.1 1858984 1861080 R catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase complement(1858984..1861080) Francisella tularensis subsp. mediasiatica FSC147 6290106 YP_001892278.1 CDS ackA NC_010677.1 1861090 1862244 R propionate kinase 2 / acetate kinase A complement(1861090..1862244) Francisella tularensis subsp. mediasiatica FSC147 6290111 YP_001892279.1 CDS ssb NC_010677.1 1862350 1862826 R single-strand DNA binding protein complement(1862350..1862826) Francisella tularensis subsp. mediasiatica FSC147 6290113 YP_001892280.1 CDS recX NC_010677.1 1863000 1863452 R regulatory protein RecX, inhibitor of RecA complement(1863000..1863452) Francisella tularensis subsp. mediasiatica FSC147 6290120 YP_001892281.1 CDS recA NC_010677.1 1863439 1864518 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(1863439..1864518) Francisella tularensis subsp. mediasiatica FSC147 6290126 YP_001892282.1 CDS secB1 NC_010677.1 1864540 1864989 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(1864540..1864989) Francisella tularensis subsp. mediasiatica FSC147 6290133 YP_001892283.1 CDS FTM_1726 NC_010677.1 1865016 1865438 R rhodanese-related sulfurtransferase complement(1865016..1865438) Francisella tularensis subsp. mediasiatica FSC147 6290144 YP_001892284.1 CDS FTM_1727 NC_010677.1 1865574 1866113 R outer membrane protein complement(1865574..1866113) Francisella tularensis subsp. mediasiatica FSC147 6290146 YP_001892285.1 CDS FTM_1728 NC_010677.1 1866203 1867126 R serine peptidase, S49 family complement(1866203..1867126) Francisella tularensis subsp. mediasiatica FSC147 6290163 YP_001892286.1 CDS idpC NC_010677.1 1867657 1869354 D indolepyruvate decarboxylase 1867657..1869354 Francisella tularensis subsp. mediasiatica FSC147 6290170 YP_001892287.1 CDS FTM_1733 NC_010677.1 1871639 1873318 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein complement(1871639..1873318) Francisella tularensis subsp. mediasiatica FSC147 6290198 YP_001892288.1 CDS FTM_1734 NC_010677.1 1873531 1874772 D metabolite:H+ symporter (MHS) family protein 1873531..1874772 Francisella tularensis subsp. mediasiatica FSC147 6290201 YP_001892289.1 CDS FTM_1735 NC_010677.1 1875161 1875286 R hypothetical protein complement(1875161..1875286) Francisella tularensis subsp. mediasiatica FSC147 6290202 YP_001892290.1 CDS FTM_1736 NC_010677.1 1875332 1876312 D hypothetical protein 1875332..1876312 Francisella tularensis subsp. mediasiatica FSC147 6290203 YP_001892291.1 CDS FTM_1738 NC_010677.1 1877038 1877958 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 1877038..1877958 Francisella tularensis subsp. mediasiatica FSC147 6290209 YP_001892292.1 CDS FTM_1741 NC_010677.1 1879479 1879799 D hypothetical protein 1879479..1879799 Francisella tularensis subsp. mediasiatica FSC147 6290216 YP_001892293.1 CDS pepN NC_010677.1 1880930 1883506 R aminopeptidase N complement(1880930..1883506) Francisella tularensis subsp. mediasiatica FSC147 6290217 YP_001892294.1 CDS FTM_1743 NC_010677.1 1883708 1884136 D heat shock protein, HSP20 family 1883708..1884136 Francisella tularensis subsp. mediasiatica FSC147 6290221 YP_001892295.1 CDS trpC NC_010677.1 1884133 1885494 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1884133..1885494) Francisella tularensis subsp. mediasiatica FSC147 6290224 YP_001892296.1 CDS FTM_1745 NC_010677.1 1885586 1885999 R hypothetical protein complement(1885586..1885999) Francisella tularensis subsp. mediasiatica FSC147 6290231 YP_001892297.1 CDS FTM_1748 NC_010677.1 1887137 1887478 R hypothetical protein complement(1887137..1887478) Francisella tularensis subsp. mediasiatica FSC147 6290243 YP_001892298.1 CDS FTM_1749 NC_010677.1 1887547 1887987 R hypothetical protein complement(1887547..1887987) Francisella tularensis subsp. mediasiatica FSC147 6290246 YP_001892299.1 CDS trpD NC_010677.1 1888049 1889062 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1888049..1889062) Francisella tularensis subsp. mediasiatica FSC147 6290249 YP_001892300.1 CDS trpG NC_010677.1 1889059 1889637 R anthranilate synthase component II complement(1889059..1889637) Francisella tularensis subsp. mediasiatica FSC147 6290253 YP_001892301.1 CDS trpE NC_010677.1 1889641 1891185 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1889641..1891185) Francisella tularensis subsp. mediasiatica FSC147 6290256 YP_001892302.1 CDS trpR NC_010677.1 1891194 1891481 R trp operon repressor complement(1891194..1891481) Francisella tularensis subsp. mediasiatica FSC147 6290258 YP_001892303.1 CDS rng NC_010677.1 1891956 1893452 R ribonuclease G complement(1891956..1893452) Francisella tularensis subsp. mediasiatica FSC147 6290269 FTM_0111 tRNA FTM_0111 NC_010677.1 120419 120495 D tRNA-Met 120419..120495 Francisella tularensis subsp. mediasiatica FSC147 6290694 FTM_0146 tRNA FTM_0146 NC_010677.1 156368 156453 D tRNA-Leu 156368..156453 Francisella tularensis subsp. mediasiatica FSC147 6291405 FTM_0198 tRNA FTM_0198 NC_010677.1 222352 222436 D tRNA-Tyr 222352..222436 Francisella tularensis subsp. mediasiatica FSC147 6290242 FTM_0199 tRNA FTM_0199 NC_010677.1 222438 222511 D tRNA-Gly 222438..222511 Francisella tularensis subsp. mediasiatica FSC147 6290877 FTM_0200 tRNA FTM_0200 NC_010677.1 222539 222614 D tRNA-Thr 222539..222614 Francisella tularensis subsp. mediasiatica FSC147 6290432 FTM_0202 tRNA FTM_0202 NC_010677.1 223863 223938 D tRNA-Trp 223863..223938 Francisella tularensis subsp. mediasiatica FSC147 6290672 FTM_0238 tRNA FTM_0238 NC_010677.1 262165 262240 D tRNA-Arg 262165..262240 Francisella tularensis subsp. mediasiatica FSC147 6290693 FTM_0242 tRNA FTM_0242 NC_010677.1 265798 265874 R tRNA-Met complement(265798..265874) Francisella tularensis subsp. mediasiatica FSC147 6291616 FTM_0334 tRNA FTM_0334 NC_010677.1 372206 372282 R tRNA-Met complement(372206..372282) Francisella tularensis subsp. mediasiatica FSC147 6290381 FTM_0409 tRNA FTM_0409 NC_010677.1 457381 457455 R tRNA-Gly complement(457381..457455) Francisella tularensis subsp. mediasiatica FSC147 6290317 FTM_0410 tRNA FTM_0410 NC_010677.1 457470 457546 R tRNA-Arg complement(457470..457546) Francisella tularensis subsp. mediasiatica FSC147 6291248 FTM_0443 tRNA FTM_0443 NC_010677.1 491322 491411 D tRNA-Ser 491322..491411 Francisella tularensis subsp. mediasiatica FSC147 6290893 FTM_0526 tRNA FTM_0526 NC_010677.1 574764 574855 D tRNA-Ser 574764..574855 Francisella tularensis subsp. mediasiatica FSC147 6291237 FTM_0527 tRNA FTM_0527 NC_010677.1 574883 574958 D tRNA-Val 574883..574958 Francisella tularensis subsp. mediasiatica FSC147 6291264 FTM_0531 tRNA FTM_0531 NC_010677.1 577826 577902 D tRNA-Ile 577826..577902 Francisella tularensis subsp. mediasiatica FSC147 6291294 FTM_0532 tRNA FTM_0532 NC_010677.1 577917 577992 D tRNA-Ala 577917..577992 Francisella tularensis subsp. mediasiatica FSC147 6291296 FTM_0611 tRNA FTM_0611 NC_010677.1 672564 672639 R tRNA-Asn complement(672564..672639) Francisella tularensis subsp. mediasiatica FSC147 6291485 FTM_0620 tRNA FTM_0620 NC_010677.1 679891 679965 D tRNA-Gly 679891..679965 Francisella tularensis subsp. mediasiatica FSC147 6291394 FTM_0621 tRNA FTM_0621 NC_010677.1 679981 680054 D tRNA-Cys 679981..680054 Francisella tularensis subsp. mediasiatica FSC147 6291376 FTM_0622 tRNA FTM_0622 NC_010677.1 680060 680148 D tRNA-Leu 680060..680148 Francisella tularensis subsp. mediasiatica FSC147 6291338 FTM_0769 tRNA FTM_0769 NC_010677.1 834337 834424 R tRNA-Ser complement(834337..834424) Francisella tularensis subsp. mediasiatica FSC147 6290044 FTM_0879 tRNA FTM_0879 NC_010677.1 960828 960904 R tRNA-Val complement(960828..960904) Francisella tularensis subsp. mediasiatica FSC147 6290283 FTM_1030 tRNA FTM_1030 NC_010677.1 1112401 1112483 R tRNA-Leu complement(1112401..1112483) Francisella tularensis subsp. mediasiatica FSC147 6290603 FTM_1031 tRNA FTM_1031 NC_010677.1 1112490 1112565 R tRNA-His complement(1112490..1112565) Francisella tularensis subsp. mediasiatica FSC147 6290604 FTM_1032 tRNA FTM_1032 NC_010677.1 1112593 1112669 R tRNA-Arg complement(1112593..1112669) Francisella tularensis subsp. mediasiatica FSC147 6290605 FTM_1033 tRNA FTM_1033 NC_010677.1 1112678 1112754 R tRNA-Pro complement(1112678..1112754) Francisella tularensis subsp. mediasiatica FSC147 6290607 FTM_1034 tRNA FTM_1034 NC_010677.1 1112772 1112847 R tRNA-Phe complement(1112772..1112847) Francisella tularensis subsp. mediasiatica FSC147 6290608 FTM_1083 tRNA FTM_1083 NC_010677.1 1159150 1159225 R tRNA-Ala complement(1159150..1159225) Francisella tularensis subsp. mediasiatica FSC147 6290734 FTM_1084 tRNA FTM_1084 NC_010677.1 1159240 1159316 R tRNA-Ile complement(1159240..1159316) Francisella tularensis subsp. mediasiatica FSC147 6290735 FTM_1341 tRNA FTM_1341 NC_010677.1 1436920 1436995 R tRNA-Lys complement(1436920..1436995) Francisella tularensis subsp. mediasiatica FSC147 6290357 FTM_1380 tRNA FTM_1380 NC_010677.1 1485334 1485409 R tRNA-Val complement(1485334..1485409) Francisella tularensis subsp. mediasiatica FSC147 6290500 FTM_1476 tRNA FTM_1476 NC_010677.1 1589882 1589968 R tRNA-Leu complement(1589882..1589968) Francisella tularensis subsp. mediasiatica FSC147 6291266 FTM_1542 tRNA FTM_1542 NC_010677.1 1649500 1649575 R tRNA-Glu complement(1649500..1649575) Francisella tularensis subsp. mediasiatica FSC147 6291437 FTM_1593 tRNA FTM_1593 NC_010677.1 1705711 1705785 D tRNA-Gln 1705711..1705785 Francisella tularensis subsp. mediasiatica FSC147 6290938 FTM_1693 tRNA FTM_1693 NC_010677.1 1822867 1822942 R tRNA-Ala complement(1822867..1822942) Francisella tularensis subsp. mediasiatica FSC147 6290899 FTM_1694 tRNA FTM_1694 NC_010677.1 1822957 1823033 R tRNA-Ile complement(1822957..1823033) Francisella tularensis subsp. mediasiatica FSC147 6291461 FTM_1754 tRNA FTM_1754 NC_010677.1 1891737 1891813 R tRNA-Asp complement(1891737..1891813) Francisella tularensis subsp. mediasiatica FSC147 6290260 FTM_1755 tRNA FTM_1755 NC_010677.1 1891818 1891893 R tRNA-Thr complement(1891818..1891893) Francisella tularensis subsp. mediasiatica FSC147 6290262 FTM_0530 rRNA FTM_0530 NC_010677.1 576207 577730 D 16S ribosomal RNA 576207..577730 Francisella tularensis subsp. mediasiatica FSC147 6291278 FTM_0533 rRNA FTM_0533 NC_010677.1 578066 580927 D 23S ribosomal RNA 578066..580927 Francisella tularensis subsp. mediasiatica FSC147 6291304 FTM_0534 rRNA FTM_0534 NC_010677.1 580978 581092 D 5S ribosomal RNA 580978..581092 Francisella tularensis subsp. mediasiatica FSC147 6291323 FTM_1081 rRNA FTM_1081 NC_010677.1 1156050 1156164 R 5S ribosomal RNA complement(1156050..1156164) Francisella tularensis subsp. mediasiatica FSC147 6290730 FTM_1082 rRNA FTM_1082 NC_010677.1 1156215 1159076 R 23S ribosomal RNA complement(1156215..1159076) Francisella tularensis subsp. mediasiatica FSC147 6290731 FTM_1085 rRNA FTM_1085 NC_010677.1 1159412 1160935 R 16S ribosomal RNA complement(1159412..1160935) Francisella tularensis subsp. mediasiatica FSC147 6290736 FTM_1691 rRNA FTM_1691 NC_010677.1 1819767 1819881 R 5S ribosomal RNA complement(1819767..1819881) Francisella tularensis subsp. mediasiatica FSC147 6291535 FTM_1692 rRNA FTM_1692 NC_010677.1 1819932 1822793 R 23S ribosomal RNA complement(1819932..1822793) Francisella tularensis subsp. mediasiatica FSC147 6291273 FTM_1695 rRNA FTM_1695 NC_010677.1 1823129 1824652 R 16S ribosomal RNA complement(1823129..1824652) Francisella tularensis subsp. mediasiatica FSC147 6291460