-- dump date   	20140619_100358
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
767434000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
767434000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
767434000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434000004	ATP binding site [chemical binding]; other site
767434000005	Walker B motif; other site
767434000006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
767434000007	arginine finger; other site
767434000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
767434000009	DnaA box-binding interface [nucleotide binding]; other site
767434000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
767434000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
767434000012	putative DNA binding surface [nucleotide binding]; other site
767434000013	dimer interface [polypeptide binding]; other site
767434000014	beta-clamp/clamp loader binding surface; other site
767434000015	beta-clamp/translesion DNA polymerase binding surface; other site
767434000016	recombination protein F; Reviewed; Region: recF; PRK00064
767434000017	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434000018	Walker A/P-loop; other site
767434000019	ATP binding site [chemical binding]; other site
767434000020	Q-loop/lid; other site
767434000021	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434000022	ABC transporter signature motif; other site
767434000023	Walker B; other site
767434000024	D-loop; other site
767434000025	H-loop/switch region; other site
767434000026	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
767434000027	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434000028	Mg2+ binding site [ion binding]; other site
767434000029	G-X-G motif; other site
767434000030	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
767434000031	anchoring element; other site
767434000032	dimer interface [polypeptide binding]; other site
767434000033	ATP binding site [chemical binding]; other site
767434000034	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
767434000035	active site
767434000036	putative metal-binding site [ion binding]; other site
767434000037	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
767434000038	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434000039	TPR motif; other site
767434000040	binding surface
767434000041	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
767434000042	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
767434000043	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
767434000044	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
767434000045	TolR protein; Region: tolR; TIGR02801
767434000046	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
767434000047	TolR protein; Region: tolR; TIGR02801
767434000048	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
767434000049	Domain of unknown function (DUF336); Region: DUF336; pfam03928
767434000050	DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533
767434000051	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
767434000052	FeS/SAM binding site; other site
767434000053	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
767434000054	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
767434000055	Walker A/P-loop; other site
767434000056	ATP binding site [chemical binding]; other site
767434000057	Q-loop/lid; other site
767434000058	ABC transporter signature motif; other site
767434000059	Walker B; other site
767434000060	D-loop; other site
767434000061	H-loop/switch region; other site
767434000062	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
767434000063	DNA-binding site [nucleotide binding]; DNA binding site
767434000064	Acetyl esterase (deacetylase) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3458
767434000065	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
767434000066	Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387
767434000067	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
767434000068	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
767434000069	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
767434000070	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
767434000071	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
767434000072	uncharacterized xylulose kinase-like proteins; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_XK_like_1; cd07804
767434000073	N- and C-terminal domain interface [polypeptide binding]; other site
767434000074	putative active site [active]
767434000075	MgATP binding site [chemical binding]; other site
767434000076	catalytic site [active]
767434000077	metal binding site [ion binding]; metal-binding site
767434000078	putative xylulose binding site [chemical binding]; other site
767434000079	putative homodimer interface [polypeptide binding]; other site
767434000080	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
767434000081	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434000082	putative substrate translocation pore; other site
767434000083	fructose-1,6-bisphosphatase family protein; Region: PLN02628
767434000084	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
767434000085	AMP binding site [chemical binding]; other site
767434000086	metal binding site [ion binding]; metal-binding site
767434000087	active site
767434000088	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
767434000089	OmpW family; Region: OmpW; cl17427
767434000090	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
767434000091	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
767434000092	putative acyl-acceptor binding pocket; other site
767434000093	putative hydrolase; Provisional; Region: PRK10985
767434000094	Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133
767434000095	Bacterial protein of unknown function (DUF883); Region: DUF883; cl01888
767434000096	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
767434000097	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
767434000098	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
767434000099	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
767434000100	putative peptidase; Provisional; Region: PRK11649
767434000101	Peptidase family M23; Region: Peptidase_M23; pfam01551
767434000102	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
767434000103	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
767434000104	active site
767434000105	HIGH motif; other site
767434000106	dimer interface [polypeptide binding]; other site
767434000107	KMSKS motif; other site
767434000108	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
767434000109	active site
767434000110	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
767434000111	putative active site [active]
767434000112	putative catalytic site [active]
767434000113	putative DNA binding site [nucleotide binding]; other site
767434000114	putative phosphate binding site [ion binding]; other site
767434000115	metal binding site A [ion binding]; metal-binding site
767434000116	putative AP binding site [nucleotide binding]; other site
767434000117	putative metal binding site B [ion binding]; other site
767434000118	muropeptide transporter; Validated; Region: ampG; cl17669
767434000119	muropeptide transporter; Reviewed; Region: ampG; PRK11902
767434000120	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
767434000121	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
767434000122	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
767434000123	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
767434000124	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434000125	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434000126	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
767434000127	Bacterial protein of unknown function (Gcw_chp); Region: Gcw_chp; cl09901
767434000128	proline/glycine betaine transporter; Provisional; Region: PRK10642
767434000129	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434000130	putative substrate translocation pore; other site
767434000131	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
767434000132	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
767434000133	active site
767434000134	intersubunit interface [polypeptide binding]; other site
767434000135	catalytic residue [active]
767434000136	phosphogluconate dehydratase; Validated; Region: PRK09054
767434000137	6-phosphogluconate dehydratase; Region: edd; TIGR01196
767434000138	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
767434000139	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
767434000140	putative active site [active]
767434000141	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
767434000142	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
767434000143	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
767434000144	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
767434000145	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
767434000146	DNA-binding site [nucleotide binding]; DNA binding site
767434000147	UTRA domain; Region: UTRA; pfam07702
767434000148	Major royal jelly protein; Region: MRJP; pfam03022
767434000149	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
767434000150	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
767434000151	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
767434000152	active site
767434000153	N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) [Cell envelope biogenesis, outer membrane]; Region: GlmU; COG1207
767434000154	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
767434000155	Substrate binding site; other site
767434000156	Mg++ binding site; other site
767434000157	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
767434000158	active site
767434000159	substrate binding site [chemical binding]; other site
767434000160	CoA binding site [chemical binding]; other site
767434000161	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
767434000162	active site
767434000163	catalytic residues [active]
767434000164	Uncharacterized conserved protein [Function unknown]; Region: COG3391
767434000165	Phosphopantetheine attachment site; Region: PP-binding; cl09936
767434000166	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
767434000167	putative acyl-acceptor binding pocket; other site
767434000168	Predicted exporter [General function prediction only]; Region: COG4258
767434000169	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
767434000170	active site 2 [active]
767434000171	active site 1 [active]
767434000172	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
767434000173	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
767434000174	Ligand binding site; other site
767434000175	Putative Catalytic site; other site
767434000176	DXD motif; other site
767434000177	Beta-ketoacyl synthase, N-terminal domain; Region: Ketoacyl-synt_2; pfam13723
767434000178	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK09185
767434000179	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
767434000180	dimer interface [polypeptide binding]; other site
767434000181	active site
767434000182	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
767434000183	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
767434000184	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
767434000185	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
767434000186	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
767434000187	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
767434000188	dimerization interface [polypeptide binding]; other site
767434000189	putative DNA binding site [nucleotide binding]; other site
767434000190	putative Zn2+ binding site [ion binding]; other site
767434000191	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
767434000192	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434000193	NAD(P) binding site [chemical binding]; other site
767434000194	active site
767434000195	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
767434000196	catalytic core [active]
767434000197	Membrane fusogenic activity; Region: BMFP; pfam04380
767434000198	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
767434000199	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
767434000200	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
767434000201	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
767434000202	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
767434000203	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
767434000204	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
767434000205	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
767434000206	TrkA-N domain; Region: TrkA_N; pfam02254
767434000207	isocitrate lyase; Provisional; Region: PRK15063
767434000208	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
767434000209	tetramer interface [polypeptide binding]; other site
767434000210	active site
767434000211	Mg2+/Mn2+ binding site [ion binding]; other site
767434000212	malate synthase A; Region: malate_syn_A; TIGR01344
767434000213	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
767434000214	active site
767434000215	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434000216	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434000217	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
767434000218	dimerization interface [polypeptide binding]; other site
767434000219	isocitrate dehydrogenase; Validated; Region: PRK07362
767434000220	isocitrate dehydrogenase; Reviewed; Region: PRK07006
767434000221	Isocitrate dehydrogenase kinase/phosphatase (AceK); Region: AceK; cl01891
767434000222	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
767434000223	TraB family; Region: TraB; pfam01963
767434000224	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
767434000225	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
767434000226	active site
767434000227	catalytic tetrad [active]
767434000228	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
767434000229	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434000230	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
767434000231	dimerization interface [polypeptide binding]; other site
767434000232	substrate binding pocket [chemical binding]; other site
767434000233	LabA_like proteins; Region: LabA_like; cd06167
767434000234	Uncharacterized conserved protein [Function unknown]; Region: COG1432
767434000235	putative metal binding site [ion binding]; other site
767434000236	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
767434000237	pseudouridine synthase; Region: TIGR00093
767434000238	active site
767434000239	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
767434000240	active site
767434000241	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
767434000242	type II secretion system protein E; Region: type_II_gspE; TIGR02533
767434000243	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
767434000244	Walker A motif; other site
767434000245	ATP binding site [chemical binding]; other site
767434000246	Walker B motif; other site
767434000247	type II secretion system protein F; Region: GspF; TIGR02120
767434000248	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
767434000249	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
767434000250	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
767434000251	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
767434000252	general secretion pathway protein J; Validated; Region: PRK08808
767434000253	Type II secretory pathway, component PulK [Intracellular trafficking and secretion]; Region: PulK; COG3156
767434000254	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
767434000255	Type II secretion system (T2SS), protein M subtype b; Region: T2SM_b; pfam10741
767434000256	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
767434000257	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
767434000258	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
767434000259	pilus (MSHA type) biogenesis protein MshL; Region: pilus_MshL; TIGR02519
767434000260	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
767434000261	ATP-dependent helicase HrpB; Region: DEAH_box_HrpB; TIGR01970
767434000262	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
767434000263	ATP binding site [chemical binding]; other site
767434000264	putative Mg++ binding site [ion binding]; other site
767434000265	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
767434000266	nucleotide binding region [chemical binding]; other site
767434000267	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
767434000268	benzoate transporter; Region: benE; TIGR00843
767434000269	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
767434000270	Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; Region: Fiu; COG4774
767434000271	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434000272	N-terminal plug; other site
767434000273	ligand-binding site [chemical binding]; other site
767434000274	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
767434000275	Ligand Binding Site [chemical binding]; other site
767434000276	RNase_H superfamily; Region: RNase_H_2; pfam13482
767434000277	helicase/secretion neighborhood putative DEAH-box helicase; Region: DECH_helic; TIGR03817
767434000278	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
767434000279	ATP binding site [chemical binding]; other site
767434000280	putative Mg++ binding site [ion binding]; other site
767434000281	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
767434000282	nucleotide binding region [chemical binding]; other site
767434000283	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
767434000284	Bacterial DNA-binding protein; Region: Bac_DNA_binding; pfam00216
767434000285	IHF dimer interface [polypeptide binding]; other site
767434000286	IHF - DNA interface [nucleotide binding]; other site
767434000287	Uncharacterized protein conserved in bacteria (DUF2058); Region: DUF2058; pfam09831
767434000288	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
767434000289	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
767434000290	active site
767434000291	catalytic tetrad [active]
767434000292	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
767434000293	dimer interface [polypeptide binding]; other site
767434000294	putative radical transfer pathway; other site
767434000295	diiron center [ion binding]; other site
767434000296	tyrosyl radical; other site
767434000297	ribonucleoside--diphosphate reductase large subunit; Region: PLN02437
767434000298	ATP cone domain; Region: ATP-cone; pfam03477
767434000299	Class I ribonucleotide reductase; Region: RNR_I; cd01679
767434000300	active site
767434000301	dimer interface [polypeptide binding]; other site
767434000302	catalytic residues [active]
767434000303	effector binding site; other site
767434000304	R2 peptide binding site; other site
767434000305	AMP-binding domain protein; Validated; Region: PRK08315
767434000306	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
767434000307	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_2; cd05917
767434000308	acyl-activating enzyme (AAE) consensus motif; other site
767434000309	acyl-activating enzyme (AAE) consensus motif; other site
767434000310	putative AMP binding site [chemical binding]; other site
767434000311	putative active site [active]
767434000312	putative CoA binding site [chemical binding]; other site
767434000313	hypothetical protein; Provisional; Region: PRK05409
767434000314	Uncharacterized protein conserved in bacteria (DUF2063); Region: DUF2063; pfam09836
767434000315	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428; cl00437
767434000316	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
767434000317	Peptidase family M23; Region: Peptidase_M23; pfam01551
767434000318	CDP-diacylglycerol pyrophosphatase; Region: CDH; cl00934
767434000319	Putative catalytic domain, repeat 1, of vertebrate phospholipases, PLD3, PLD4 and PLD5, viral envelope proteins K4 and p37, and similar proteins; Region: PLDc_vPLD3_4_5_like_1; cd09106
767434000320	PLD-like domain; Region: PLDc_2; pfam13091
767434000321	putative active site [active]
767434000322	putative catalytic site [active]
767434000323	Putative catalytic domain, repeat 2, of vertebrate phospholipases, PLD3, PLD4 and PLD5, viral envelope proteins K4 and p37, and similar proteins; Region: PLDc_vPLD3_4_5_like_2; cd09107
767434000324	PLD-like domain; Region: PLDc_2; pfam13091
767434000325	putative active site [active]
767434000326	putative catalytic site [active]
767434000327	Peptidase S46; Region: Peptidase_S46; pfam10459
767434000328	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
767434000329	Predicted ATPase [General function prediction only]; Region: COG1485
767434000330	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434000331	Walker A/P-loop; other site
767434000332	ATP binding site [chemical binding]; other site
767434000333	ABC transporter signature motif; other site
767434000334	Walker B; other site
767434000335	D-loop; other site
767434000336	H-loop/switch region; other site
767434000337	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945
767434000338	Protein of unknown function, DUF479; Region: DUF479; cl01203
767434000339	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
767434000340	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
767434000341	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
767434000342	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
767434000343	Protein export membrane protein; Region: SecD_SecF; cl14618
767434000344	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
767434000345	non-specific DNA binding site [nucleotide binding]; other site
767434000346	salt bridge; other site
767434000347	sequence-specific DNA binding site [nucleotide binding]; other site
767434000348	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
767434000349	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434000350	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434000351	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
767434000352	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434000353	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434000354	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434000355	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
767434000356	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434000357	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434000358	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434000359	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
767434000360	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434000361	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
767434000362	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
767434000363	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
767434000364	dimer interface [polypeptide binding]; other site
767434000365	motif 1; other site
767434000366	active site
767434000367	motif 2; other site
767434000368	motif 3; other site
767434000369	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
767434000370	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
767434000371	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
767434000372	Walker A motif; other site
767434000373	ATP binding site [chemical binding]; other site
767434000374	Walker B motif; other site
767434000375	Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: Triacylglycerol_lipase_like; cd01847
767434000376	active site
767434000377	catalytic triad [active]
767434000378	oxyanion hole [active]
767434000379	Autotransporter beta-domain; Region: Autotransporter; smart00869
767434000380	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
767434000381	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
767434000382	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
767434000383	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
767434000384	RNA binding site [nucleotide binding]; other site
767434000385	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
767434000386	RDD family; Region: RDD; pfam06271
767434000387	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
767434000388	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
767434000389	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
767434000390	aminopeptidase N; Provisional; Region: pepN; PRK14015
767434000391	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
767434000392	Zn binding site [ion binding]; other site
767434000393	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
767434000394	active site
767434000395	catalytic residues [active]
767434000396	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
767434000397	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
767434000398	putative ADP-ribose binding site [chemical binding]; other site
767434000399	putative active site [active]
767434000400	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
767434000401	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
767434000402	NAD(P) binding site [chemical binding]; other site
767434000403	catalytic residues [active]
767434000404	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
767434000405	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434000406	S-adenosylmethionine binding site [chemical binding]; other site
767434000407	pimelyl-[acyl-carrier protein] methyl ester esterase; Region: bioH; TIGR01738
767434000408	rhodanese superfamily protein; Provisional; Region: PRK05320
767434000409	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
767434000410	active site residue [active]
767434000411	threonine dehydratase; Reviewed; Region: PRK09224
767434000412	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
767434000413	tetramer interface [polypeptide binding]; other site
767434000414	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434000415	catalytic residue [active]
767434000416	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
767434000417	putative Ile/Val binding site [chemical binding]; other site
767434000418	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
767434000419	putative Ile/Val binding site [chemical binding]; other site
767434000420	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
767434000421	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
767434000422	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
767434000423	catalytic residue [active]
767434000424	biotin synthase; Region: bioB; TIGR00433
767434000425	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
767434000426	FeS/SAM binding site; other site
767434000427	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
767434000428	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
767434000429	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
767434000430	active site
767434000431	Protein of unknown function (DUF2968); Region: DUF2968; pfam11180
767434000432	Predicted membrane protein [Function unknown]; Region: COG4655
767434000433	Protein of unknown function (DUF3613); Region: DUF3613; pfam12266
767434000434	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434000435	binding surface
767434000436	TPR motif; other site
767434000437	Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: TadC; COG2064
767434000438	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
767434000439	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
767434000440	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
767434000441	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
767434000442	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
767434000443	ATP binding site [chemical binding]; other site
767434000444	Walker A motif; other site
767434000445	hexamer interface [polypeptide binding]; other site
767434000446	Walker B motif; other site
767434000447	AAA domain; Region: AAA_31; pfam13614
767434000448	This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains...; Region: CpaE_like; cd03111
767434000449	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
767434000450	Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629
767434000451	Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion]; Region: CpaC; COG4964
767434000452	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
767434000453	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
767434000454	Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: CpaA; COG4960
767434000455	Flp/Fap pilin component; Region: Flp_Fap; cl01585
767434000456	Helix-turn-helix domain; Region: HTH_18; pfam12833
767434000457	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434000458	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
767434000459	UbiA prenyltransferase family; Region: UbiA; pfam01040
767434000460	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
767434000461	active site
767434000462	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
767434000463	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
767434000464	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
767434000465	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
767434000466	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
767434000467	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
767434000468	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
767434000469	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
767434000470	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
767434000471	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
767434000472	beta subunit interaction interface [polypeptide binding]; other site
767434000473	Walker A motif; other site
767434000474	ATP binding site [chemical binding]; other site
767434000475	Walker B motif; other site
767434000476	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
767434000477	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
767434000478	core domain interface [polypeptide binding]; other site
767434000479	delta subunit interface [polypeptide binding]; other site
767434000480	epsilon subunit interface [polypeptide binding]; other site
767434000481	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
767434000482	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
767434000483	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
767434000484	alpha subunit interaction interface [polypeptide binding]; other site
767434000485	Walker A motif; other site
767434000486	ATP binding site [chemical binding]; other site
767434000487	Walker B motif; other site
767434000488	inhibitor binding site; inhibition site
767434000489	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
767434000490	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
767434000491	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
767434000492	gamma subunit interface [polypeptide binding]; other site
767434000493	epsilon subunit interface [polypeptide binding]; other site
767434000494	LBP interface [polypeptide binding]; other site
767434000495	PhoPQ-activated pathogenicity-related protein; Region: PhoPQ_related; cl01750
767434000496	MarR family; Region: MarR_2; cl17246
767434000497	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
767434000498	Pirin-related protein [General function prediction only]; Region: COG1741
767434000499	Pirin; Region: Pirin; pfam02678
767434000500	Protein of unknown function (DUF3224); Region: DUF3224; pfam11528
767434000501	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
767434000502	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
767434000503	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
767434000504	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
767434000505	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
767434000506	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
767434000507	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
767434000508	Transcriptional regulators [Transcription]; Region: FadR; COG2186
767434000509	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
767434000510	DNA-binding site [nucleotide binding]; DNA binding site
767434000511	FCD domain; Region: FCD; pfam07729
767434000512	Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318
767434000513	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
767434000514	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
767434000515	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
767434000516	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434000517	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434000518	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
767434000519	Predicted archaeal methyltransferase [General function prediction only]; Region: COG2521
767434000520	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434000521	S-adenosylmethionine binding site [chemical binding]; other site
767434000522	putative S-transferase; Provisional; Region: PRK11752
767434000523	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
767434000524	C-terminal domain interface [polypeptide binding]; other site
767434000525	GSH binding site (G-site) [chemical binding]; other site
767434000526	dimer interface [polypeptide binding]; other site
767434000527	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
767434000528	N-terminal domain interface [polypeptide binding]; other site
767434000529	dimer interface [polypeptide binding]; other site
767434000530	substrate binding pocket (H-site) [chemical binding]; other site
767434000531	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
767434000532	Uncharacterized conserved protein [Function unknown]; Region: COG3189
767434000533	Dibenzothiophene (DBT) desulfurization enzyme C; Region: DszC; cd01163
767434000534	sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022
767434000535	Flavin binding site [chemical binding]; other site
767434000536	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
767434000537	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
767434000538	active site
767434000539	non-prolyl cis peptide bond; other site
767434000540	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_15; cd08492
767434000541	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
767434000542	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
767434000543	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
767434000544	dimer interface [polypeptide binding]; other site
767434000545	conserved gate region; other site
767434000546	putative PBP binding loops; other site
767434000547	ABC-ATPase subunit interface; other site
767434000548	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
767434000549	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
767434000550	putative PBP binding loops; other site
767434000551	ABC-ATPase subunit interface; other site
767434000552	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
767434000553	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
767434000554	Walker A/P-loop; other site
767434000555	ATP binding site [chemical binding]; other site
767434000556	Q-loop/lid; other site
767434000557	ABC transporter signature motif; other site
767434000558	Walker B; other site
767434000559	D-loop; other site
767434000560	H-loop/switch region; other site
767434000561	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
767434000562	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
767434000563	Walker A/P-loop; other site
767434000564	ATP binding site [chemical binding]; other site
767434000565	Q-loop/lid; other site
767434000566	ABC transporter signature motif; other site
767434000567	Walker B; other site
767434000568	D-loop; other site
767434000569	H-loop/switch region; other site
767434000570	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
767434000571	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
767434000572	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434000573	Walker A motif; other site
767434000574	ATP binding site [chemical binding]; other site
767434000575	Walker B motif; other site
767434000576	arginine finger; other site
767434000577	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
767434000578	sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022
767434000579	Dibenzothiophene (DBT) desulfurization enzyme C; Region: DszC; cd01163
767434000580	Flavin binding site [chemical binding]; other site
767434000581	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
767434000582	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
767434000583	active site
767434000584	dimer interface [polypeptide binding]; other site
767434000585	non-prolyl cis peptide bond; other site
767434000586	insertion regions; other site
767434000587	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
767434000588	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
767434000589	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
767434000590	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
767434000591	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
767434000592	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
767434000593	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
767434000594	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
767434000595	catalytic loop [active]
767434000596	iron binding site [ion binding]; other site
767434000597	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
767434000598	Cytochrome c; Region: Cytochrom_C; pfam00034
767434000599	Protein of unknown function (DUF1269); Region: DUF1269; cl01978
767434000600	multiple promoter invertase; Provisional; Region: mpi; PRK13413
767434000601	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
767434000602	catalytic residues [active]
767434000603	catalytic nucleophile [active]
767434000604	Presynaptic Site I dimer interface [polypeptide binding]; other site
767434000605	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
767434000606	Synaptic Flat tetramer interface [polypeptide binding]; other site
767434000607	Synaptic Site I dimer interface [polypeptide binding]; other site
767434000608	DNA binding site [nucleotide binding]
767434000609	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
767434000610	DNA-binding interface [nucleotide binding]; DNA binding site
767434000611	AAA domain; Region: AAA_23; pfam13476
767434000612	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434000613	Walker A/P-loop; other site
767434000614	ATP binding site [chemical binding]; other site
767434000615	AAA domain; Region: AAA_21; pfam13304
767434000616	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434000617	ABC transporter signature motif; other site
767434000618	Walker B; other site
767434000619	D-loop; other site
767434000620	H-loop/switch region; other site
767434000621	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
767434000622	active site
767434000623	Int/Topo IB signature motif; other site
767434000624	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
767434000625	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
767434000626	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
767434000627	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
767434000628	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
767434000629	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
767434000630	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
767434000631	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
767434000632	DNA binding residues [nucleotide binding]
767434000633	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
767434000634	putative active site [active]
767434000635	dimerization interface [polypeptide binding]; other site
767434000636	putative tRNAtyr binding site [nucleotide binding]; other site
767434000637	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
767434000638	putative acyl-acceptor binding pocket; other site
767434000639	TPR repeat; Region: TPR_11; pfam13414
767434000640	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
767434000641	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
767434000642	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
767434000643	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
767434000644	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
767434000645	putative metal binding site; other site
767434000646	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
767434000647	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
767434000648	active site
767434000649	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
767434000650	N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase; Region: GT2_Chondriotin_Pol_N; cd06420
767434000651	Substrate binding site; other site
767434000652	metal-binding site
767434000653	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
767434000654	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
767434000655	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
767434000656	DNA binding site [nucleotide binding]
767434000657	Catalytic domain of Protein Kinases; Region: PKc; cd00180
767434000658	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
767434000659	active site
767434000660	ATP binding site [chemical binding]; other site
767434000661	substrate binding site [chemical binding]; other site
767434000662	activation loop (A-loop); other site
767434000663	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434000664	TPR motif; other site
767434000665	binding surface
767434000666	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
767434000667	HNH endonuclease; Region: HNH_2; pfam13391
767434000668	Cupin; Region: Cupin_6; pfam12852
767434000669	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
767434000670	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434000671	short chain dehydrogenase; Validated; Region: PRK06182
767434000672	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
767434000673	NADP binding site [chemical binding]; other site
767434000674	active site
767434000675	steroid binding site; other site
767434000676	oxidative damage protection protein; Provisional; Region: PRK05408
767434000677	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
767434000678	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
767434000679	minor groove reading motif; other site
767434000680	helix-hairpin-helix signature motif; other site
767434000681	substrate binding pocket [chemical binding]; other site
767434000682	active site
767434000683	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
767434000684	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
767434000685	DNA binding and oxoG recognition site [nucleotide binding]
767434000686	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
767434000687	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
767434000688	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
767434000689	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
767434000690	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434000691	S-adenosylmethionine binding site [chemical binding]; other site
767434000692	Class I aldolases; Region: Aldolase_Class_I; cl17187
767434000693	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
767434000694	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
767434000695	active site
767434000696	(T/H)XGH motif; other site
767434000697	benzoyl-CoA oxygenase/reductase, BoxA protein; Region: benzo_boxA; TIGR03224
767434000698	Protein of unknown function (DUF1625); Region: DUF1625; pfam07787
767434000699	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
767434000700	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
767434000701	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
767434000702	dimer interface [polypeptide binding]; other site
767434000703	ADP-ribose binding site [chemical binding]; other site
767434000704	active site
767434000705	nudix motif; other site
767434000706	metal binding site [ion binding]; metal-binding site
767434000707	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
767434000708	5'-3' exonuclease; Region: 53EXOc; smart00475
767434000709	active site
767434000710	metal binding site 1 [ion binding]; metal-binding site
767434000711	putative 5' ssDNA interaction site; other site
767434000712	metal binding site 3; metal-binding site
767434000713	metal binding site 2 [ion binding]; metal-binding site
767434000714	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
767434000715	putative DNA binding site [nucleotide binding]; other site
767434000716	putative metal binding site [ion binding]; other site
767434000717	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
767434000718	putative FMN binding site [chemical binding]; other site
767434000719	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
767434000720	active site
767434000721	catalytic motif [active]
767434000722	Zn binding site [ion binding]; other site
767434000723	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
767434000724	RNA polymerase factor sigma-70; Validated; Region: PRK09047
767434000725	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
767434000726	DNA binding residues [nucleotide binding]
767434000727	probable FeS assembly SUF system protein SufT; Region: FeS_long_SufT; TIGR03406
767434000728	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
767434000729	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
767434000730	ligand binding site [chemical binding]; other site
767434000731	flexible hinge region; other site
767434000732	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
767434000733	putative switch regulator; other site
767434000734	non-specific DNA interactions [nucleotide binding]; other site
767434000735	DNA binding site [nucleotide binding]
767434000736	sequence specific DNA binding site [nucleotide binding]; other site
767434000737	putative cAMP binding site [chemical binding]; other site
767434000738	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
767434000739	pyrroloquinoline quinone biosynthesis protein PqqB; Provisional; Region: PRK05184
767434000740	coenzyme PQQ biosynthesis protein B; Region: PQQ_syn_pqqB; TIGR02108
767434000741	pyrroloquinoline quinone biosynthesis protein PqqC; Provisional; Region: PRK05157
767434000742	Coenzyme PQQ synthesis protein D (PqqD); Region: PqqD; pfam05402
767434000743	pyrroloquinoline quinone biosynthesis protein PqqE; Provisional; Region: PRK05301
767434000744	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
767434000745	FeS/SAM binding site; other site
767434000746	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
767434000747	Demethoxyubiquinone hydroxylase, ferritin-like diiron-binding domain; Region: DMQH; cd01042
767434000748	diiron binding motif [ion binding]; other site
767434000749	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
767434000750	23S rRNA interface [nucleotide binding]; other site
767434000751	L3 interface [polypeptide binding]; other site
767434000752	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
767434000753	Ketosteroid isomerase-related protein [General function prediction only]; Region: COG3631
767434000754	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434000755	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434000756	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434000757	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434000758	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_1; cd08460
767434000759	putative substrate binding pocket [chemical binding]; other site
767434000760	putative dimerization interface [polypeptide binding]; other site
767434000761	Methyltransferase domain; Region: Methyltransf_31; pfam13847
767434000762	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434000763	S-adenosylmethionine binding site [chemical binding]; other site
767434000764	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
767434000765	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
767434000766	salt bridge; other site
767434000767	non-specific DNA binding site [nucleotide binding]; other site
767434000768	sequence-specific DNA binding site [nucleotide binding]; other site
767434000769	atypical (a) SDRs, subgroup 7; Region: SDR_a7; cd05262
767434000770	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
767434000771	putative NAD(P) binding site [chemical binding]; other site
767434000772	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
767434000773	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
767434000774	RNA binding surface [nucleotide binding]; other site
767434000775	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
767434000776	active site
767434000777	RIO kinase family; RIO1, RIO3 and similar proteins, catalytic domain. The RIO kinase catalytic domain family is part of a larger superfamily, that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; Region: RIO1_like; cd05145
767434000778	ATP binding site [chemical binding]; other site
767434000779	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
767434000780	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
767434000781	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
767434000782	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
767434000783	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
767434000784	Protein export membrane protein; Region: SecD_SecF; cl14618
767434000785	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
767434000786	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
767434000787	HlyD family secretion protein; Region: HlyD_3; pfam13437
767434000788	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
767434000789	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
767434000790	Transcriptional regulators [Transcription]; Region: FadR; COG2186
767434000791	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
767434000792	DNA-binding site [nucleotide binding]; DNA binding site
767434000793	FCD domain; Region: FCD; pfam07729
767434000794	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
767434000795	galactarate dehydratase; Region: galactar-dH20; TIGR03248
767434000796	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
767434000797	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
767434000798	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
767434000799	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
767434000800	Protein of unknown function (DUF445); Region: DUF445; pfam04286
767434000801	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
767434000802	Mechanosensitive ion channel; Region: MS_channel; pfam00924
767434000803	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
767434000804	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
767434000805	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
767434000806	shikimate binding site; other site
767434000807	NAD(P) binding site [chemical binding]; other site
767434000808	RimK-like ATPgrasp N-terminal domain; Region: RLAN; pfam14401
767434000809	Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Coenzyme metabolism / Translation, ribosomal structure and biogenesis]; Region: RimK; COG0189
767434000810	ATP-grasp domain; Region: ATP-grasp_4; cl17255
767434000811	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
767434000812	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
767434000813	Coenzyme A binding pocket [chemical binding]; other site
767434000814	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
767434000815	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
767434000816	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
767434000817	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
767434000818	Protein of unknown function, DUF484; Region: DUF484; cl17449
767434000819	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
767434000820	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
767434000821	active site
767434000822	DNA binding site [nucleotide binding]
767434000823	Int/Topo IB signature motif; other site
767434000824	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
767434000825	active site
767434000826	HslU subunit interaction site [polypeptide binding]; other site
767434000827	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
767434000828	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434000829	Walker A motif; other site
767434000830	ATP binding site [chemical binding]; other site
767434000831	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
767434000832	Walker B motif; other site
767434000833	arginine finger; other site
767434000834	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
767434000835	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
767434000836	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
767434000837	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
767434000838	ATP-grasp domain; Region: ATP-grasp_4; cl17255
767434000839	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
767434000840	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434000841	active site
767434000842	phosphorylation site [posttranslational modification]
767434000843	intermolecular recognition site; other site
767434000844	dimerization interface [polypeptide binding]; other site
767434000845	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
767434000846	DNA binding site [nucleotide binding]
767434000847	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
767434000848	HAMP domain; Region: HAMP; pfam00672
767434000849	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434000850	dimer interface [polypeptide binding]; other site
767434000851	phosphorylation site [posttranslational modification]
767434000852	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434000853	ATP binding site [chemical binding]; other site
767434000854	Mg2+ binding site [ion binding]; other site
767434000855	G-X-G motif; other site
767434000856	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
767434000857	The adenylation domain of nonribosomal peptide synthetases (NRPS), including salinosporamide A polyketide synthase; Region: A_NRPS_Ta1_like; cd12116
767434000858	acyl-activating enzyme (AAE) consensus motif; other site
767434000859	AMP binding site [chemical binding]; other site
767434000860	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
767434000861	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
767434000862	active site
767434000863	TDP-binding site; other site
767434000864	acceptor substrate-binding pocket; other site
767434000865	homodimer interface [polypeptide binding]; other site
767434000866	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
767434000867	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
767434000868	active site
767434000869	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
767434000870	L-rhamnosyltransferase; Region: rhamnosyltran; TIGR01556
767434000871	active site
767434000872	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
767434000873	FAD binding site [chemical binding]; other site
767434000874	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
767434000875	Predicted transporter component [General function prediction only]; Region: COG2391
767434000876	Sulphur transport; Region: Sulf_transp; pfam04143
767434000877	Domain of unknown function (DUF4341); Region: DUF4341; pfam14241
767434000878	Predicted transporter component [General function prediction only]; Region: COG2391
767434000879	Sulphur transport; Region: Sulf_transp; pfam04143
767434000880	Adenosylhomocysteinase; Provisional; Region: PTZ00075
767434000881	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
767434000882	homotetramer interface [polypeptide binding]; other site
767434000883	ligand binding site [chemical binding]; other site
767434000884	catalytic site [active]
767434000885	NAD binding site [chemical binding]; other site
767434000886	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
767434000887	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
767434000888	Isochorismatase family; Region: Isochorismatase; pfam00857
767434000889	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
767434000890	catalytic triad [active]
767434000891	conserved cis-peptide bond; other site
767434000892	Glycosyl hydrolases family 32; Region: Glyco_32; smart00640
767434000893	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
767434000894	substrate binding [chemical binding]; other site
767434000895	active site
767434000896	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
767434000897	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
767434000898	active site
767434000899	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
767434000900	catalytic tetrad [active]
767434000901	ABC transporter ATPase component; Reviewed; Region: PRK11147
767434000902	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434000903	Walker A/P-loop; other site
767434000904	ATP binding site [chemical binding]; other site
767434000905	Q-loop/lid; other site
767434000906	ABC transporter signature motif; other site
767434000907	Walker B; other site
767434000908	D-loop; other site
767434000909	H-loop/switch region; other site
767434000910	ABC transporter; Region: ABC_tran_2; pfam12848
767434000911	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
767434000912	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
767434000913	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
767434000914	xylulokinase; Provisional; Region: PRK15027
767434000915	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
767434000916	N- and C-terminal domain interface [polypeptide binding]; other site
767434000917	active site
767434000918	MgATP binding site [chemical binding]; other site
767434000919	catalytic site [active]
767434000920	metal binding site [ion binding]; metal-binding site
767434000921	xylulose binding site [chemical binding]; other site
767434000922	homodimer interface [polypeptide binding]; other site
767434000923	Uncharacterized conserved protein [Function unknown]; Region: COG1284
767434000924	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
767434000925	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
767434000926	S-adenosylmethionine synthetase; Validated; Region: PRK05250
767434000927	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
767434000928	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
767434000929	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
767434000930	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
767434000931	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
767434000932	THF binding site; other site
767434000933	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
767434000934	substrate binding site [chemical binding]; other site
767434000935	THF binding site; other site
767434000936	zinc-binding site [ion binding]; other site
767434000937	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
767434000938	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
767434000939	FMN binding site [chemical binding]; other site
767434000940	active site
767434000941	catalytic residues [active]
767434000942	substrate binding site [chemical binding]; other site
767434000943	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
767434000944	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
767434000945	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
767434000946	Nucleoside recognition; Region: Gate; pfam07670
767434000947	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
767434000948	LysE type translocator; Region: LysE; cl00565
767434000949	hypothetical protein; Reviewed; Region: PRK12497
767434000950	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
767434000951	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
767434000952	putative ligand binding site [chemical binding]; other site
767434000953	Predicted methyltransferases [General function prediction only]; Region: COG0313
767434000954	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
767434000955	putative SAM binding site [chemical binding]; other site
767434000956	putative homodimer interface [polypeptide binding]; other site
767434000957	cell division protein MraZ; Reviewed; Region: PRK00326
767434000958	MraZ protein; Region: MraZ; pfam02381
767434000959	MraZ protein; Region: MraZ; pfam02381
767434000960	MraW methylase family; Region: Methyltransf_5; cl17771
767434000961	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
767434000962	Cell division protein FtsL; Region: FtsL; pfam04999
767434000963	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
767434000964	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
767434000965	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
767434000966	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
767434000967	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
767434000968	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
767434000969	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
767434000970	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
767434000971	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
767434000972	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
767434000973	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
767434000974	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
767434000975	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
767434000976	Mg++ binding site [ion binding]; other site
767434000977	putative catalytic motif [active]
767434000978	putative substrate binding site [chemical binding]; other site
767434000979	cell division protein FtsW; Region: ftsW; TIGR02614
767434000980	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
767434000981	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
767434000982	active site
767434000983	homodimer interface [polypeptide binding]; other site
767434000984	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
767434000985	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
767434000986	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
767434000987	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
767434000988	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
767434000989	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
767434000990	ATP-grasp domain; Region: ATP-grasp_4; cl17255
767434000991	cell division protein FtsQ; Provisional; Region: PRK10775
767434000992	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
767434000993	Cell division protein FtsQ; Region: FtsQ; pfam03799
767434000994	cell division protein FtsA; Region: ftsA; TIGR01174
767434000995	Cell division protein FtsA; Region: FtsA; smart00842
767434000996	Cell division protein FtsA; Region: FtsA; pfam14450
767434000997	cell division protein FtsZ; Validated; Region: PRK09330
767434000998	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
767434000999	nucleotide binding site [chemical binding]; other site
767434001000	SulA interaction site; other site
767434001001	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
767434001002	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
767434001003	Protein of unknown function (DUF721); Region: DUF721; cl02324
767434001004	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
767434001005	DEAD/DEAH box helicase; Region: DEAD; pfam00270
767434001006	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
767434001007	SEC-C motif; Region: SEC-C; pfam02810
767434001008	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
767434001009	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
767434001010	active site
767434001011	metal binding site [ion binding]; metal-binding site
767434001012	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
767434001013	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
767434001014	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
767434001015	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
767434001016	SurA N-terminal domain; Region: SurA_N; pfam09312
767434001017	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
767434001018	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
767434001019	organic solvent tolerance protein; Provisional; Region: PRK04423
767434001020	Organic solvent tolerance protein; Region: OstA_C; pfam04453
767434001021	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
767434001022	Histone deacetylases and histone-like deacetylases, classII; Region: HDAC_classII_2; cd11599
767434001023	putative active site [active]
767434001024	Zn binding site [ion binding]; other site
767434001025	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
767434001026	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
767434001027	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984
767434001028	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
767434001029	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
767434001030	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
767434001031	dimer interface [polypeptide binding]; other site
767434001032	catalytic triad [active]
767434001033	peroxidatic and resolving cysteines [active]
767434001034	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
767434001035	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
767434001036	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
767434001037	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
767434001038	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
767434001039	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
767434001040	catalytic residue [active]
767434001041	S1/P1 nucleases and related enzymes; Region: S1-P1_nuclease; cd11010
767434001042	active site
767434001043	Zn binding site [ion binding]; other site
767434001044	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
767434001045	pyruvate kinase; Provisional; Region: PRK05826
767434001046	domain interfaces; other site
767434001047	active site
767434001048	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
767434001049	Fructose-1,6-bisphosphate aldolase; Region: FBP_aldolase_I_a; cd00948
767434001050	active site
767434001051	intersubunit interface [polypeptide binding]; other site
767434001052	catalytic residue [active]
767434001053	transketolase; Reviewed; Region: PRK12753
767434001054	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
767434001055	TPP-binding site [chemical binding]; other site
767434001056	dimer interface [polypeptide binding]; other site
767434001057	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
767434001058	PYR/PP interface [polypeptide binding]; other site
767434001059	dimer interface [polypeptide binding]; other site
767434001060	TPP binding site [chemical binding]; other site
767434001061	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
767434001062	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
767434001063	tetramer (dimer of dimers) interface [polypeptide binding]; other site
767434001064	active site
767434001065	dimer interface [polypeptide binding]; other site
767434001066	Uncharacterized conserved protein [Function unknown]; Region: COG2947
767434001067	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212
767434001068	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
767434001069	Cell division protein ZapA; Region: ZapA; pfam05164
767434001070	TIGR02449 family protein; Region: TIGR02449
767434001071	Uncharacterized protein family (UPF0149); Region: UPF0149; cl01173
767434001072	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
767434001073	proline aminopeptidase P II; Provisional; Region: PRK10879
767434001074	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
767434001075	active site
767434001076	proline dipeptidase; Provisional; Region: PRK13607
767434001077	Aminopeptidase P, N-terminal domain; Region: AMP_N; cl08433
767434001078	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
767434001079	active site
767434001080	HemN family oxidoreductase; Provisional; Region: PRK05660
767434001081	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
767434001082	FeS/SAM binding site; other site
767434001083	HemN C-terminal domain; Region: HemN_C; pfam06969
767434001084	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
767434001085	active site
767434001086	dimerization interface [polypeptide binding]; other site
767434001087	ribonuclease PH; Reviewed; Region: rph; PRK00173
767434001088	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
767434001089	oligomer interface [polypeptide binding]; other site
767434001090	RNA binding site [nucleotide binding]; other site
767434001091	hypothetical protein; Provisional; Region: PRK11820
767434001092	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
767434001093	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
767434001094	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
767434001095	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
767434001096	catalytic site [active]
767434001097	G-X2-G-X-G-K; other site
767434001098	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
767434001099	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
767434001100	Walker A/P-loop; other site
767434001101	ATP binding site [chemical binding]; other site
767434001102	Q-loop/lid; other site
767434001103	ABC transporter signature motif; other site
767434001104	Walker B; other site
767434001105	D-loop; other site
767434001106	H-loop/switch region; other site
767434001107	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
767434001108	Permease; Region: Permease; pfam02405
767434001109	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
767434001110	mce related protein; Region: MCE; pfam02470
767434001111	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
767434001112	mce related protein; Region: MCE; pfam02470
767434001113	Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; pfam05494
767434001114	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
767434001115	anti sigma factor interaction site; other site
767434001116	regulatory phosphorylation site [posttranslational modification]; other site
767434001117	VacJ like lipoprotein; Region: VacJ; cl01073
767434001118	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
767434001119	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
767434001120	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
767434001121	Zn2+ binding site [ion binding]; other site
767434001122	Mg2+ binding site [ion binding]; other site
767434001123	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
767434001124	synthetase active site [active]
767434001125	NTP binding site [chemical binding]; other site
767434001126	metal binding site [ion binding]; metal-binding site
767434001127	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
767434001128	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
767434001129	Transglycosylase SLT domain; Region: SLT_2; pfam13406
767434001130	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
767434001131	N-acetyl-D-glucosamine binding site [chemical binding]; other site
767434001132	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
767434001133	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
767434001134	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
767434001135	putative RNA binding site [nucleotide binding]; other site
767434001136	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434001137	S-adenosylmethionine binding site [chemical binding]; other site
767434001138	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
767434001139	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
767434001140	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434001141	short chain dehydrogenase; Provisional; Region: PRK07023
767434001142	NAD(P) binding site [chemical binding]; other site
767434001143	active site
767434001144	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
767434001145	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
767434001146	Protein of unknown function (DUF1190); Region: DUF1190; pfam06693
767434001147	serine/threonine protein kinase; Provisional; Region: PRK11768
767434001148	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
767434001149	CoenzymeA binding site [chemical binding]; other site
767434001150	subunit interaction site [polypeptide binding]; other site
767434001151	PHB binding site; other site
767434001152	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
767434001153	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
767434001154	FAD binding pocket [chemical binding]; other site
767434001155	FAD binding motif [chemical binding]; other site
767434001156	phosphate binding motif [ion binding]; other site
767434001157	beta-alpha-beta structure motif; other site
767434001158	NAD binding pocket [chemical binding]; other site
767434001159	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4307
767434001160	Uncharacterized protein conserved in bacteria (DUF2248); Region: DUF2248; pfam10005
767434001161	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
767434001162	active site
767434001163	catalytic residues [active]
767434001164	metal binding site [ion binding]; metal-binding site
767434001165	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
767434001166	nuc_hydro: Nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity.  This group contains eukaryotic, bacterial and archeal...; Region: nuc_hydro; cl00226
767434001167	active site
767434001168	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
767434001169	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
767434001170	catalytic core [active]
767434001171	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
767434001172	active site
767434001173	dimer interface [polypeptide binding]; other site
767434001174	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
767434001175	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
767434001176	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
767434001177	ABC transporter; Region: ABC_tran_2; pfam12848
767434001178	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
767434001179	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434001180	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434001181	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
767434001182	dimerization interface [polypeptide binding]; other site
767434001183	Domain of unknown function (DUF3315); Region: DUF3315; cl02275
767434001184	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
767434001185	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
767434001186	dimer interface [polypeptide binding]; other site
767434001187	active site
767434001188	glycine-pyridoxal phosphate binding site [chemical binding]; other site
767434001189	folate binding site [chemical binding]; other site
767434001190	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
767434001191	ATP cone domain; Region: ATP-cone; pfam03477
767434001192	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
767434001193	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
767434001194	catalytic motif [active]
767434001195	Zn binding site [ion binding]; other site
767434001196	RibD C-terminal domain; Region: RibD_C; cl17279
767434001197	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
767434001198	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
767434001199	dimer interface [polypeptide binding]; other site
767434001200	FMN binding site [chemical binding]; other site
767434001201	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
767434001202	Lumazine binding domain; Region: Lum_binding; pfam00677
767434001203	Lumazine binding domain; Region: Lum_binding; pfam00677
767434001204	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
767434001205	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
767434001206	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
767434001207	dimer interface [polypeptide binding]; other site
767434001208	catalytic triad [active]
767434001209	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
767434001210	homopentamer interface [polypeptide binding]; other site
767434001211	active site
767434001212	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
767434001213	thiamine monophosphate kinase; Provisional; Region: PRK05731
767434001214	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
767434001215	ATP binding site [chemical binding]; other site
767434001216	dimerization interface [polypeptide binding]; other site
767434001217	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
767434001218	tetramer interfaces [polypeptide binding]; other site
767434001219	binuclear metal-binding site [ion binding]; other site
767434001220	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
767434001221	catalytic tetrad [active]
767434001222	Hemin uptake protein hemP; Region: hemP; pfam10636
767434001223	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
767434001224	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
767434001225	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
767434001226	HlyD family secretion protein; Region: HlyD_3; pfam13437
767434001227	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
767434001228	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
767434001229	Walker A/P-loop; other site
767434001230	ATP binding site [chemical binding]; other site
767434001231	Q-loop/lid; other site
767434001232	ABC transporter signature motif; other site
767434001233	Walker B; other site
767434001234	D-loop; other site
767434001235	H-loop/switch region; other site
767434001236	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
767434001237	FtsX-like permease family; Region: FtsX; pfam02687
767434001238	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
767434001239	FtsX-like permease family; Region: FtsX; pfam02687
767434001240	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
767434001241	FtsX-like permease family; Region: FtsX; pfam02687
767434001242	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
767434001243	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
767434001244	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434001245	active site
767434001246	phosphorylation site [posttranslational modification]
767434001247	intermolecular recognition site; other site
767434001248	dimerization interface [polypeptide binding]; other site
767434001249	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434001250	Walker A motif; other site
767434001251	ATP binding site [chemical binding]; other site
767434001252	Walker B motif; other site
767434001253	arginine finger; other site
767434001254	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
767434001255	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
767434001256	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434001257	ATP binding site [chemical binding]; other site
767434001258	Mg2+ binding site [ion binding]; other site
767434001259	G-X-G motif; other site
767434001260	Predicted acyl esterases [General function prediction only]; Region: COG2936
767434001261	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
767434001262	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
767434001263	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
767434001264	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
767434001265	Uncharacterized conserved protein [Function unknown]; Region: COG2966
767434001266	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
767434001267	Protein of unknown function (DUF3815); Region: DUF3815; cl01118
767434001268	H-NS histone family; Region: Histone_HNS; pfam00816
767434001269	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
767434001270	prolyl-tRNA synthetase; Provisional; Region: PRK09194
767434001271	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
767434001272	dimer interface [polypeptide binding]; other site
767434001273	motif 1; other site
767434001274	active site
767434001275	motif 2; other site
767434001276	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
767434001277	putative deacylase active site [active]
767434001278	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
767434001279	active site
767434001280	motif 3; other site
767434001281	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
767434001282	anticodon binding site; other site
767434001283	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
767434001284	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
767434001285	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
767434001286	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
767434001287	Coenzyme A binding pocket [chemical binding]; other site
767434001288	Mitochondrial fission ELM1; Region: Mito_fiss_Elm1; pfam06258
767434001289	Uncharacterized conserved protein [Function unknown]; Region: COG2353
767434001290	Zinc-finger domain; Region: zf-CHCC; cl01821
767434001291	This family is most closely related to the GT1 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core; Region: GT1_WavL_like; cd03819
767434001292	Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439
767434001293	putative ADP-binding pocket [chemical binding]; other site
767434001294	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
767434001295	O-Antigen ligase; Region: Wzy_C; pfam04932
767434001296	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
767434001297	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
767434001298	putative metal binding site; other site
767434001299	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
767434001300	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
767434001301	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
767434001302	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
767434001303	putative active site [active]
767434001304	putative metal binding site [ion binding]; other site
767434001305	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
767434001306	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
767434001307	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
767434001308	putative acyl-acceptor binding pocket; other site
767434001309	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
767434001310	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
767434001311	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
767434001312	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
767434001313	Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: Pcm; COG2518
767434001314	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434001315	S-adenosylmethionine binding site [chemical binding]; other site
767434001316	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434001317	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434001318	AefR-like transcriptional repressor, C-terminal region; Region: TetR_C_7; pfam14246
767434001319	Ferritin-like domain; Region: Ferritin; pfam00210
767434001320	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
767434001321	dinuclear metal binding motif [ion binding]; other site
767434001322	Short repeat of unknown function (DUF308); Region: DUF308; cl15828
767434001323	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
767434001324	dimer interface [polypeptide binding]; other site
767434001325	substrate binding site [chemical binding]; other site
767434001326	metal binding sites [ion binding]; metal-binding site
767434001327	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
767434001328	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
767434001329	trimer interface [polypeptide binding]; other site
767434001330	active site
767434001331	substrate binding site [chemical binding]; other site
767434001332	CoA binding site [chemical binding]; other site
767434001333	O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425
767434001334	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
767434001335	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
767434001336	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
767434001337	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp1; TIGR03087
767434001338	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3664
767434001339	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
767434001340	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
767434001341	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
767434001342	Chain length determinant protein; Region: Wzz; cl15801
767434001343	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
767434001344	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
767434001345	SLBB domain; Region: SLBB; pfam10531
767434001346	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
767434001347	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
767434001348	active site
767434001349	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
767434001350	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
767434001351	adenylate kinase; Reviewed; Region: adk; PRK00279
767434001352	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
767434001353	AMP-binding site [chemical binding]; other site
767434001354	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
767434001355	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
767434001356	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
767434001357	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
767434001358	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
767434001359	Uncharacterized protein, similar to the N-terminal domain of Lon protease [General function prediction only]; Region: COG2802
767434001360	acetylornithine transaminase protein; Provisional; Region: argD; PRK04612
767434001361	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
767434001362	inhibitor-cofactor binding pocket; inhibition site
767434001363	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434001364	catalytic residue [active]
767434001365	putative transporter; Provisional; Region: PRK12382
767434001366	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434001367	putative substrate translocation pore; other site
767434001368	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
767434001369	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
767434001370	inhibitor-cofactor binding pocket; inhibition site
767434001371	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434001372	catalytic residue [active]
767434001373	Rubredoxin [Energy production and conversion]; Region: COG1773
767434001374	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
767434001375	iron binding site [ion binding]; other site
767434001376	heat shock protein HtpX; Provisional; Region: PRK05457
767434001377	heat shock protein 90; Provisional; Region: PRK05218
767434001378	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434001379	ATP binding site [chemical binding]; other site
767434001380	Mg2+ binding site [ion binding]; other site
767434001381	G-X-G motif; other site
767434001382	acid phosphatase, Burkholderia-type; Region: acid_phos_Burk; TIGR03397
767434001383	Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132
767434001384	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
767434001385	Multicopper oxidase; Region: Cu-oxidase; pfam00394
767434001386	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
767434001387	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
767434001388	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
767434001389	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434001390	N-terminal plug; other site
767434001391	ligand-binding site [chemical binding]; other site
767434001392	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
767434001393	Phosphotransferase enzyme family; Region: APH; pfam01636
767434001394	active site
767434001395	substrate binding site [chemical binding]; other site
767434001396	ATP binding site [chemical binding]; other site
767434001397	Membrane transport protein; Region: Mem_trans; cl09117
767434001398	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
767434001399	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
767434001400	RNA binding surface [nucleotide binding]; other site
767434001401	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231
767434001402	classical (c) SDRs; Region: SDR_c; cd05233
767434001403	NAD(P) binding site [chemical binding]; other site
767434001404	active site
767434001405	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
767434001406	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
767434001407	tetramer interface [polypeptide binding]; other site
767434001408	heme binding pocket [chemical binding]; other site
767434001409	NADPH binding site [chemical binding]; other site
767434001410	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
767434001411	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
767434001412	G1 box; other site
767434001413	GTP/Mg2+ binding site [chemical binding]; other site
767434001414	Switch I region; other site
767434001415	G3 box; other site
767434001416	Switch II region; other site
767434001417	G4 box; other site
767434001418	G5 box; other site
767434001419	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
767434001420	UreF; Region: UreF; pfam01730
767434001421	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
767434001422	dimer interface [polypeptide binding]; other site
767434001423	catalytic residues [active]
767434001424	urease subunit alpha; Reviewed; Region: ureC; PRK13207
767434001425	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
767434001426	subunit interactions [polypeptide binding]; other site
767434001427	active site
767434001428	flap region; other site
767434001429	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
767434001430	gamma-beta subunit interface [polypeptide binding]; other site
767434001431	alpha-beta subunit interface [polypeptide binding]; other site
767434001432	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
767434001433	alpha-gamma subunit interface [polypeptide binding]; other site
767434001434	beta-gamma subunit interface [polypeptide binding]; other site
767434001435	UreD urease accessory protein; Region: UreD; cl00530
767434001436	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
767434001437	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
767434001438	active site
767434001439	dimer interface [polypeptide binding]; other site
767434001440	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
767434001441	dimer interface [polypeptide binding]; other site
767434001442	active site
767434001443	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
767434001444	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
767434001445	Sulfate transporter family; Region: Sulfate_transp; pfam00916
767434001446	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
767434001447	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434001448	putative substrate translocation pore; other site
767434001449	Major Facilitator Superfamily; Region: MFS_1; pfam07690
767434001450	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
767434001451	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434001452	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
767434001453	dimerization interface [polypeptide binding]; other site
767434001454	substrate binding pocket [chemical binding]; other site
767434001455	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
767434001456	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
767434001457	active site
767434001458	dimer interface [polypeptide binding]; other site
767434001459	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
767434001460	dimer interface [polypeptide binding]; other site
767434001461	active site
767434001462	hypothetical protein; Validated; Region: PRK00029
767434001463	Uncharacterized conserved protein [Function unknown]; Region: COG0397
767434001464	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
767434001465	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
767434001466	active site
767434001467	Zn binding site [ion binding]; other site
767434001468	Nuclease-related domain; Region: NERD; pfam08378
767434001469	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3972
767434001470	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
767434001471	Family description; Region: UvrD_C_2; pfam13538
767434001472	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
767434001473	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
767434001474	Predicted acetyltransferase [General function prediction only]; Region: COG2388
767434001475	Protein of unknown function (DUF1345); Region: DUF1345; pfam07077
767434001476	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
767434001477	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
767434001478	CAP-like domain; other site
767434001479	active site
767434001480	primary dimer interface [polypeptide binding]; other site
767434001481	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
767434001482	N-formylglutamate amidohydrolase; Region: FGase; cl01522
767434001483	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
767434001484	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434001485	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434001486	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
767434001487	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
767434001488	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
767434001489	dimer interface [polypeptide binding]; other site
767434001490	conserved gate region; other site
767434001491	putative PBP binding loops; other site
767434001492	ABC-ATPase subunit interface; other site
767434001493	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
767434001494	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
767434001495	dimer interface [polypeptide binding]; other site
767434001496	conserved gate region; other site
767434001497	putative PBP binding loops; other site
767434001498	ABC-ATPase subunit interface; other site
767434001499	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
767434001500	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
767434001501	Walker A/P-loop; other site
767434001502	ATP binding site [chemical binding]; other site
767434001503	Q-loop/lid; other site
767434001504	ABC transporter signature motif; other site
767434001505	Walker B; other site
767434001506	D-loop; other site
767434001507	H-loop/switch region; other site
767434001508	TOBE domain; Region: TOBE_2; pfam08402
767434001509	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
767434001510	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
767434001511	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
767434001512	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
767434001513	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434001514	S-adenosylmethionine binding site [chemical binding]; other site
767434001515	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434001516	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434001517	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
767434001518	dimerization interface [polypeptide binding]; other site
767434001519	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
767434001520	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
767434001521	NAD(P) binding site [chemical binding]; other site
767434001522	catalytic residues [active]
767434001523	Fumarate hydratase (Fumerase); Region: Fumerase; pfam05681
767434001524	Fumarase C-terminus; Region: Fumerase_C; pfam05683
767434001525	Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505
767434001526	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
767434001527	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
767434001528	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
767434001529	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
767434001530	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
767434001531	amphipathic channel; other site
767434001532	Asn-Pro-Ala signature motifs; other site
767434001533	glycerol kinase; Provisional; Region: glpK; PRK00047
767434001534	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
767434001535	N- and C-terminal domain interface [polypeptide binding]; other site
767434001536	active site
767434001537	MgATP binding site [chemical binding]; other site
767434001538	catalytic site [active]
767434001539	metal binding site [ion binding]; metal-binding site
767434001540	glycerol binding site [chemical binding]; other site
767434001541	homotetramer interface [polypeptide binding]; other site
767434001542	homodimer interface [polypeptide binding]; other site
767434001543	FBP binding site [chemical binding]; other site
767434001544	protein IIAGlc interface [polypeptide binding]; other site
767434001545	Ribokinase-like subgroup A.  Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_A; cd01942
767434001546	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
767434001547	substrate binding site [chemical binding]; other site
767434001548	ATP binding site [chemical binding]; other site
767434001549	rod shape-determining protein MreB; Provisional; Region: PRK13927
767434001550	MreB and similar proteins; Region: MreB_like; cd10225
767434001551	nucleotide binding site [chemical binding]; other site
767434001552	Mg binding site [ion binding]; other site
767434001553	putative protofilament interaction site [polypeptide binding]; other site
767434001554	RodZ interaction site [polypeptide binding]; other site
767434001555	rod shape-determining protein MreC; Provisional; Region: PRK13922
767434001556	rod shape-determining protein MreC; Region: MreC; pfam04085
767434001557	rod shape-determining protein MreD; Region: MreD; cl01087
767434001558	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
767434001559	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
767434001560	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
767434001561	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
767434001562	Transglycosylase SLT domain; Region: SLT_2; pfam13406
767434001563	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
767434001564	N-acetyl-D-glucosamine binding site [chemical binding]; other site
767434001565	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
767434001566	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
767434001567	Sporulation related domain; Region: SPOR; pfam05036
767434001568	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
767434001569	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
767434001570	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
767434001571	Protein of unknown function (DUF493); Region: DUF493; cl01102
767434001572	lipoate-protein ligase B; Provisional; Region: PRK14342
767434001573	lipoyl synthase; Provisional; Region: PRK05481
767434001574	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
767434001575	FeS/SAM binding site; other site
767434001576	carboxy-terminal protease; Provisional; Region: PRK11186
767434001577	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
767434001578	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
767434001579	protein binding site [polypeptide binding]; other site
767434001580	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
767434001581	Catalytic dyad [active]
767434001582	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
767434001583	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
767434001584	Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260
767434001585	interface (dimer of trimers) [polypeptide binding]; other site
767434001586	Substrate-binding/catalytic site; other site
767434001587	Zn-binding sites [ion binding]; other site
767434001588	PBP superfamily domain; Region: PBP_like_2; cl17296
767434001589	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
767434001590	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
767434001591	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
767434001592	ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Region: NrdJ_Z; TIGR02504
767434001593	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
767434001594	active site
767434001595	dimer interface [polypeptide binding]; other site
767434001596	effector binding site; other site
767434001597	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
767434001598	TSCPD domain; Region: TSCPD; pfam12637
767434001599	HipA N-terminal domain; Region: Couple_hipA; cl11853
767434001600	polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707
767434001601	peptide chain release factor 1; Validated; Region: prfA; PRK00591
767434001602	This domain is found in peptide chain release factors; Region: PCRF; smart00937
767434001603	RF-1 domain; Region: RF-1; pfam00472
767434001604	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
767434001605	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
767434001606	tRNA; other site
767434001607	putative tRNA binding site [nucleotide binding]; other site
767434001608	putative NADP binding site [chemical binding]; other site
767434001609	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
767434001610	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434001611	TPR motif; other site
767434001612	binding surface
767434001613	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
767434001614	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
767434001615	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
767434001616	Coenzyme A binding pocket [chemical binding]; other site
767434001617	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
767434001618	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
767434001619	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
767434001620	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
767434001621	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
767434001622	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
767434001623	active site
767434001624	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
767434001625	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
767434001626	5S rRNA interface [nucleotide binding]; other site
767434001627	CTC domain interface [polypeptide binding]; other site
767434001628	L16 interface [polypeptide binding]; other site
767434001629	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
767434001630	putative active site [active]
767434001631	catalytic residue [active]
767434001632	GTP-binding protein YchF; Reviewed; Region: PRK09601
767434001633	YchF GTPase; Region: YchF; cd01900
767434001634	G1 box; other site
767434001635	GTP/Mg2+ binding site [chemical binding]; other site
767434001636	Switch I region; other site
767434001637	G2 box; other site
767434001638	Switch II region; other site
767434001639	G3 box; other site
767434001640	G4 box; other site
767434001641	G5 box; other site
767434001642	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
767434001643	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
767434001644	Uncharacterized conserved protein [Function unknown]; Region: COG4127
767434001645	Restriction endonuclease; Region: Mrr_cat; pfam04471
767434001646	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
767434001647	HsdM N-terminal domain; Region: HsdM_N; pfam12161
767434001648	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434001649	S-adenosylmethionine binding site [chemical binding]; other site
767434001650	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
767434001651	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
767434001652	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
767434001653	AAA domain; Region: AAA_13; pfam13166
767434001654	AAA domain; Region: AAA_13; pfam13166
767434001655	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
767434001656	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
767434001657	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
767434001658	ATP binding site [chemical binding]; other site
767434001659	putative Mg++ binding site [ion binding]; other site
767434001660	Domain of unknown function (DUF4411); Region: DUF4411; pfam14367
767434001661	Predicted Zn peptidase [Amino acid transport and metabolism]; Region: COG2856
767434001662	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
767434001663	sugar phosphate phosphatase; Provisional; Region: PRK10513
767434001664	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
767434001665	active site
767434001666	motif I; other site
767434001667	motif II; other site
767434001668	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
767434001669	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
767434001670	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434001671	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434001672	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
767434001673	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
767434001674	active site
767434001675	metal binding site [ion binding]; metal-binding site
767434001676	Domain of unknown function (DUF1338); Region: DUF1338; pfam07063
767434001677	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
767434001678	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
767434001679	elongation factor Tu; Reviewed; Region: PRK00049
767434001680	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
767434001681	G1 box; other site
767434001682	GEF interaction site [polypeptide binding]; other site
767434001683	GTP/Mg2+ binding site [chemical binding]; other site
767434001684	Switch I region; other site
767434001685	G2 box; other site
767434001686	G3 box; other site
767434001687	Switch II region; other site
767434001688	G4 box; other site
767434001689	G5 box; other site
767434001690	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
767434001691	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
767434001692	Antibiotic Binding Site [chemical binding]; other site
767434001693	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
767434001694	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
767434001695	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
767434001696	putative homodimer interface [polypeptide binding]; other site
767434001697	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
767434001698	heterodimer interface [polypeptide binding]; other site
767434001699	homodimer interface [polypeptide binding]; other site
767434001700	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
767434001701	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
767434001702	23S rRNA interface [nucleotide binding]; other site
767434001703	L7/L12 interface [polypeptide binding]; other site
767434001704	putative thiostrepton binding site; other site
767434001705	L25 interface [polypeptide binding]; other site
767434001706	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
767434001707	mRNA/rRNA interface [nucleotide binding]; other site
767434001708	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
767434001709	23S rRNA interface [nucleotide binding]; other site
767434001710	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
767434001711	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
767434001712	core dimer interface [polypeptide binding]; other site
767434001713	peripheral dimer interface [polypeptide binding]; other site
767434001714	L10 interface [polypeptide binding]; other site
767434001715	L11 interface [polypeptide binding]; other site
767434001716	putative EF-Tu interaction site [polypeptide binding]; other site
767434001717	putative EF-G interaction site [polypeptide binding]; other site
767434001718	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
767434001719	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
767434001720	MoCF_BD: molybdenum cofactor (MoCF) binding domain (BD). This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor, like MoaB, MogA, and MoeA. The domain is presumed to bind molybdopterin; Region: MoCF_BD; cl00451
767434001721	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
767434001722	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
767434001723	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
767434001724	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
767434001725	RPB1 interaction site [polypeptide binding]; other site
767434001726	RNA polymerase Rpb2, domain 7; Region: RNA_pol_Rpb2_7; pfam04560
767434001727	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
767434001728	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
767434001729	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
767434001730	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
767434001731	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
767434001732	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
767434001733	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
767434001734	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
767434001735	cleft; other site
767434001736	Rpb1 - Rpb5 interaction site [polypeptide binding]; other site
767434001737	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
767434001738	DNA binding site [nucleotide binding]
767434001739	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
767434001740	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
767434001741	S17 interaction site [polypeptide binding]; other site
767434001742	S8 interaction site; other site
767434001743	16S rRNA interaction site [nucleotide binding]; other site
767434001744	streptomycin interaction site [chemical binding]; other site
767434001745	23S rRNA interaction site [nucleotide binding]; other site
767434001746	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
767434001747	30S ribosomal protein S7; Validated; Region: PRK05302
767434001748	elongation factor G; Reviewed; Region: PRK00007
767434001749	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
767434001750	G1 box; other site
767434001751	putative GEF interaction site [polypeptide binding]; other site
767434001752	GTP/Mg2+ binding site [chemical binding]; other site
767434001753	Switch I region; other site
767434001754	G2 box; other site
767434001755	G3 box; other site
767434001756	Switch II region; other site
767434001757	G4 box; other site
767434001758	G5 box; other site
767434001759	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
767434001760	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
767434001761	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
767434001762	elongation factor Tu; Reviewed; Region: PRK00049
767434001763	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
767434001764	G1 box; other site
767434001765	GEF interaction site [polypeptide binding]; other site
767434001766	GTP/Mg2+ binding site [chemical binding]; other site
767434001767	Switch I region; other site
767434001768	G2 box; other site
767434001769	G3 box; other site
767434001770	Switch II region; other site
767434001771	G4 box; other site
767434001772	G5 box; other site
767434001773	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
767434001774	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
767434001775	Antibiotic Binding Site [chemical binding]; other site
767434001776	Nitronate monooxygenase; Region: NMO; pfam03060
767434001777	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
767434001778	FMN binding site [chemical binding]; other site
767434001779	substrate binding site [chemical binding]; other site
767434001780	putative catalytic residue [active]
767434001781	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
767434001782	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434001783	N-terminal plug; other site
767434001784	ligand-binding site [chemical binding]; other site
767434001785	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
767434001786	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
767434001787	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
767434001788	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
767434001789	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
767434001790	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
767434001791	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
767434001792	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
767434001793	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
767434001794	putative translocon binding site; other site
767434001795	protein-rRNA interface [nucleotide binding]; other site
767434001796	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
767434001797	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
767434001798	G-X-X-G motif; other site
767434001799	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
767434001800	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
767434001801	23S rRNA interface [nucleotide binding]; other site
767434001802	5S rRNA interface [nucleotide binding]; other site
767434001803	putative antibiotic binding site [chemical binding]; other site
767434001804	L25 interface [polypeptide binding]; other site
767434001805	L27 interface [polypeptide binding]; other site
767434001806	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
767434001807	putative translocon interaction site; other site
767434001808	signal recognition particle (SRP54) interaction site; other site
767434001809	L23 interface [polypeptide binding]; other site
767434001810	trigger factor interaction site; other site
767434001811	23S rRNA interface [nucleotide binding]; other site
767434001812	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
767434001813	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
767434001814	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
767434001815	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
767434001816	RNA binding site [nucleotide binding]; other site
767434001817	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
767434001818	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
767434001819	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
767434001820	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
767434001821	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
767434001822	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
767434001823	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
767434001824	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
767434001825	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
767434001826	5S rRNA interface [nucleotide binding]; other site
767434001827	23S rRNA interface [nucleotide binding]; other site
767434001828	L5 interface [polypeptide binding]; other site
767434001829	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
767434001830	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
767434001831	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
767434001832	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
767434001833	23S rRNA binding site [nucleotide binding]; other site
767434001834	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
767434001835	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
767434001836	SecY translocase; Region: SecY; pfam00344
767434001837	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
767434001838	30S ribosomal protein S13; Region: bact_S13; TIGR03631
767434001839	30S ribosomal protein S11; Validated; Region: PRK05309
767434001840	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
767434001841	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
767434001842	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
767434001843	RNA binding surface [nucleotide binding]; other site
767434001844	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
767434001845	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
767434001846	alphaNTD homodimer interface [polypeptide binding]; other site
767434001847	alphaNTD - beta interaction site [polypeptide binding]; other site
767434001848	alphaNTD - beta' interaction site [polypeptide binding]; other site
767434001849	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
767434001850	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
767434001851	Disulfide bond formation protein DsbB; Region: DsbB; cl00649
767434001852	Class-II DAHP synthetase family; Region: DAHP_synth_2; pfam01474
767434001853	Cytochrome c; Region: Cytochrom_C; cl11414
767434001854	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434001855	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434001856	Cytochrome c; Region: Cytochrom_C; pfam00034
767434001857	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
767434001858	active site
767434001859	SUMO-1 interface [polypeptide binding]; other site
767434001860	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
767434001861	Mechanosensitive ion channel; Region: MS_channel; pfam00924
767434001862	ribonuclease G; Provisional; Region: PRK11712
767434001863	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
767434001864	homodimer interface [polypeptide binding]; other site
767434001865	oligonucleotide binding site [chemical binding]; other site
767434001866	TIGR02099 family protein; Region: TIGR02099
767434001867	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
767434001868	protease TldD; Provisional; Region: tldD; PRK10735
767434001869	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
767434001870	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
767434001871	PA/protease or protease-like domain interface [polypeptide binding]; other site
767434001872	M28 Zn-Peptidases containing a PA domain insert; Region: M28_like_PA; cd03877
767434001873	Peptidase family M28; Region: Peptidase_M28; pfam04389
767434001874	metal binding site [ion binding]; metal-binding site
767434001875	FtsX-like permease family; Region: FtsX; pfam02687
767434001876	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
767434001877	FtsX-like permease family; Region: FtsX; pfam02687
767434001878	YceI-like domain; Region: YceI; pfam04264
767434001879	hypothetical protein; Provisional; Region: PRK05255
767434001880	Protein of unknown function (DUF1653); Region: DUF1653; pfam07866
767434001881	peptidase PmbA; Provisional; Region: PRK11040
767434001882	Tic20-like protein; Region: Tic20; pfam09685
767434001883	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
767434001884	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
767434001885	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
767434001886	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
767434001887	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
767434001888	Ligand Binding Site [chemical binding]; other site
767434001889	TilS substrate binding domain; Region: TilS; pfam09179
767434001890	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
767434001891	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
767434001892	active site
767434001893	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
767434001894	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
767434001895	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
767434001896	putative active site [active]
767434001897	heme pocket [chemical binding]; other site
767434001898	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
767434001899	PAS domain; Region: PAS_9; pfam13426
767434001900	putative active site [active]
767434001901	heme pocket [chemical binding]; other site
767434001902	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
767434001903	putative CheW interface [polypeptide binding]; other site
767434001904	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
767434001905	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; pfam03255
767434001906	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
767434001907	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
767434001908	putative active site [active]
767434001909	putative PHP Thumb interface [polypeptide binding]; other site
767434001910	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
767434001911	generic binding surface II; other site
767434001912	generic binding surface I; other site
767434001913	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845
767434001914	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845
767434001915	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
767434001916	RNA/DNA hybrid binding site [nucleotide binding]; other site
767434001917	active site
767434001918	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
767434001919	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
767434001920	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
767434001921	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
767434001922	active site
767434001923	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
767434001924	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
767434001925	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
767434001926	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
767434001927	trimer interface [polypeptide binding]; other site
767434001928	active site
767434001929	UDP-GlcNAc binding site [chemical binding]; other site
767434001930	lipid binding site [chemical binding]; lipid-binding site
767434001931	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
767434001932	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
767434001933	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
767434001934	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
767434001935	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
767434001936	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
767434001937	Surface antigen; Region: Bac_surface_Ag; pfam01103
767434001938	zinc metallopeptidase RseP; Provisional; Region: PRK10779
767434001939	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
767434001940	active site
767434001941	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
767434001942	protein binding site [polypeptide binding]; other site
767434001943	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
767434001944	protein binding site [polypeptide binding]; other site
767434001945	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
767434001946	putative substrate binding region [chemical binding]; other site
767434001947	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
767434001948	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
767434001949	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
767434001950	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
767434001951	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
767434001952	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
767434001953	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
767434001954	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
767434001955	catalytic residue [active]
767434001956	putative FPP diphosphate  binding site; other site
767434001957	putative FPP binding hydrophobic cleft; other site
767434001958	dimer interface [polypeptide binding]; other site
767434001959	putative IPP diphosphate binding site; other site
767434001960	ribosome recycling factor; Reviewed; Region: frr; PRK00083
767434001961	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
767434001962	hinge region; other site
767434001963	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
767434001964	putative nucleotide binding site [chemical binding]; other site
767434001965	uridine monophosphate binding site [chemical binding]; other site
767434001966	homohexameric interface [polypeptide binding]; other site
767434001967	elongation factor Ts; Provisional; Region: tsf; PRK09377
767434001968	UBA/TS-N domain; Region: UBA; pfam00627
767434001969	Elongation factor TS; Region: EF_TS; pfam00889
767434001970	Elongation factor TS; Region: EF_TS; pfam00889
767434001971	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
767434001972	rRNA interaction site [nucleotide binding]; other site
767434001973	S8 interaction site; other site
767434001974	putative laminin-1 binding site; other site
767434001975	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
767434001976	active site
767434001977	PII uridylyl-transferase; Provisional; Region: PRK05007
767434001978	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
767434001979	metal binding triad; other site
767434001980	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
767434001981	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
767434001982	Zn2+ binding site [ion binding]; other site
767434001983	Mg2+ binding site [ion binding]; other site
767434001984	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
767434001985	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
767434001986	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434001987	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434001988	metal binding site [ion binding]; metal-binding site
767434001989	active site
767434001990	I-site; other site
767434001991	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
767434001992	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
767434001993	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
767434001994	trimer interface [polypeptide binding]; other site
767434001995	active site
767434001996	substrate binding site [chemical binding]; other site
767434001997	CoA binding site [chemical binding]; other site
767434001998	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
767434001999	ArsC family; Region: ArsC; pfam03960
767434002000	putative catalytic residues [active]
767434002001	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
767434002002	dinuclear metal binding motif [ion binding]; other site
767434002003	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_2; cd02433
767434002004	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
767434002005	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
767434002006	metal binding site [ion binding]; metal-binding site
767434002007	dimer interface [polypeptide binding]; other site
767434002008	Predicted periplasmic protein [Function unknown]; Region: COG3698
767434002009	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
767434002010	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
767434002011	putative active site [active]
767434002012	nucleotide binding site [chemical binding]; other site
767434002013	nudix motif; other site
767434002014	putative metal binding site [ion binding]; other site
767434002015	Glutaredoxin-like domain (DUF836); Region: DUF836; pfam05768
767434002016	YceI-like domain; Region: YceI; smart00867
767434002017	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
767434002018	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
767434002019	dimerization interface [polypeptide binding]; other site
767434002020	substrate binding site [chemical binding]; other site
767434002021	active site
767434002022	calcium binding site [ion binding]; other site
767434002023	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
767434002024	DNA-binding site [nucleotide binding]; DNA binding site
767434002025	RNA-binding motif; other site
767434002026	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
767434002027	DNA-binding site [nucleotide binding]; DNA binding site
767434002028	RNA-binding motif; other site
767434002029	Predicted alpha/beta hydrolase [General function prediction only]; Region: COG4757
767434002030	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
767434002031	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
767434002032	putative ATP binding site [chemical binding]; other site
767434002033	putative substrate interface [chemical binding]; other site
767434002034	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
767434002035	acetoacetyl-CoA reductase; Region: AcAcCoA_reduct; TIGR01829
767434002036	NAD(P) binding site [chemical binding]; other site
767434002037	homotetramer interface [polypeptide binding]; other site
767434002038	homodimer interface [polypeptide binding]; other site
767434002039	active site
767434002040	glutamyl-queuosine tRNA(Asp) synthetase; Region: queuosine_YadB; TIGR03838
767434002041	active site
767434002042	nucleotide binding site [chemical binding]; other site
767434002043	HIGH motif; other site
767434002044	KMSKS motif; other site
767434002045	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
767434002046	catalytic residues [active]
767434002047	hinge region; other site
767434002048	alpha helical domain; other site
767434002049	Competence-damaged protein; Region: CinA; cl00666
767434002050	recombinase A; Provisional; Region: recA; PRK09354
767434002051	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
767434002052	hexamer interface [polypeptide binding]; other site
767434002053	Walker A motif; other site
767434002054	ATP binding site [chemical binding]; other site
767434002055	Walker B motif; other site
767434002056	recombination regulator RecX; Reviewed; Region: recX; PRK00117
767434002057	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
767434002058	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
767434002059	motif 1; other site
767434002060	active site
767434002061	motif 2; other site
767434002062	motif 3; other site
767434002063	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
767434002064	carbon storage regulator; Provisional; Region: PRK01712
767434002065	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
767434002066	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
767434002067	Nitrilases, cyanide hydratase (CH)s, and similar proteins (class 1 nitrilases); Region: nitrilases_CHs; cd07564
767434002068	Predicted amidohydrolase [General function prediction only]; Region: COG0388
767434002069	putative active site [active]
767434002070	catalytic triad [active]
767434002071	putative dimer interface [polypeptide binding]; other site
767434002072	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism]; Region: FhuE; COG4773
767434002073	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434002074	N-terminal plug; other site
767434002075	ligand-binding site [chemical binding]; other site
767434002076	squalene-hopene cyclase; Region: hopene_cyclase; TIGR01507
767434002077	Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY)  and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; Region: SQCY_1; cd02892
767434002078	Active site cavity [active]
767434002079	catalytic acid [active]
767434002080	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434002081	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434002082	Domain of unknown function (DUF336); Region: DUF336; cl01249
767434002083	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
767434002084	GAF domain; Region: GAF_2; pfam13185
767434002085	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
767434002086	AAA domain; Region: AAA_26; pfam13500
767434002087	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
767434002088	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
767434002089	active site
767434002090	Zn binding site [ion binding]; other site
767434002091	Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318
767434002092	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
767434002093	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
767434002094	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434002095	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434002096	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
767434002097	Domain of unknown function (DUF336); Region: DUF336; cl01249
767434002098	glutamate--cysteine ligase; Region: PLN02611
767434002099	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
767434002100	transcription termination factor Rho; Provisional; Region: rho; PRK09376
767434002101	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
767434002102	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
767434002103	RNA binding site [nucleotide binding]; other site
767434002104	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
767434002105	multimer interface [polypeptide binding]; other site
767434002106	Walker A motif; other site
767434002107	ATP binding site [chemical binding]; other site
767434002108	Walker B motif; other site
767434002109	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
767434002110	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
767434002111	catalytic residues [active]
767434002112	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
767434002113	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
767434002114	ATP binding site [chemical binding]; other site
767434002115	Mg++ binding site [ion binding]; other site
767434002116	motif III; other site
767434002117	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
767434002118	nucleotide binding region [chemical binding]; other site
767434002119	ATP-binding site [chemical binding]; other site
767434002120	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
767434002121	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
767434002122	Walker A/P-loop; other site
767434002123	ATP binding site [chemical binding]; other site
767434002124	Q-loop/lid; other site
767434002125	ABC transporter signature motif; other site
767434002126	Walker B; other site
767434002127	D-loop; other site
767434002128	H-loop/switch region; other site
767434002129	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
767434002130	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
767434002131	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
767434002132	ligand binding site [chemical binding]; other site
767434002133	active site
767434002134	UGI interface [polypeptide binding]; other site
767434002135	catalytic site [active]
767434002136	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
767434002137	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
767434002138	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
767434002139	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
767434002140	DNA binding residues [nucleotide binding]
767434002141	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
767434002142	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434002143	active site
767434002144	phosphorylation site [posttranslational modification]
767434002145	intermolecular recognition site; other site
767434002146	dimerization interface [polypeptide binding]; other site
767434002147	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
767434002148	DNA binding site [nucleotide binding]
767434002149	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
767434002150	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
767434002151	dimerization interface [polypeptide binding]; other site
767434002152	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434002153	ATP binding site [chemical binding]; other site
767434002154	Mg2+ binding site [ion binding]; other site
767434002155	G-X-G motif; other site
767434002156	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
767434002157	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
767434002158	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
767434002159	lipoyl-biotinyl attachment site [posttranslational modification]; other site
767434002160	HlyD family secretion protein; Region: HlyD_3; pfam13437
767434002161	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
767434002162	transaldolase-like protein; Provisional; Region: PTZ00411
767434002163	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
767434002164	active site
767434002165	dimer interface [polypeptide binding]; other site
767434002166	catalytic residue [active]
767434002167	primosome assembly protein PriA; Validated; Region: PRK05580
767434002168	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
767434002169	ATP binding site [chemical binding]; other site
767434002170	putative Mg++ binding site [ion binding]; other site
767434002171	Ring finger domain; Region: zf-RING_2; pfam13639
767434002172	helicase superfamily c-terminal domain; Region: HELICc; smart00490
767434002173	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
767434002174	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
767434002175	cation binding site [ion binding]; other site
767434002176	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cl00216
767434002177	active site
767434002178	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
767434002179	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
767434002180	ribonuclease BN/unknown domain fusion protein; Reviewed; Region: rbn; PRK04214
767434002181	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
767434002182	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
767434002183	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
767434002184	catalytic residues [active]
767434002185	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
767434002186	acyl-CoA dehydrogenase; Provisional; Region: PTZ00456
767434002187	Acyl-CoA dehydrogenase N terminal; Region: AcylCoA_DH_N; pfam12418
767434002188	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
767434002189	active site
767434002190	Acetyl-CoA dehydrogenase C-terminal like; Region: Acyl-CoA_dh_C; pfam12806
767434002191	Late embryogenesis abundant protein; Region: LEA_2; pfam03168
767434002192	Proteins containing SET domain [General function prediction only]; Region: COG2940
767434002193	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; Region: SET; smart00317
767434002194	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
767434002195	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
767434002196	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
767434002197	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
767434002198	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
767434002199	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
767434002200	Switch I; other site
767434002201	Switch II; other site
767434002202	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
767434002203	septum formation inhibitor; Reviewed; Region: minC; PRK04596
767434002204	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
767434002205	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
767434002206	Coenzyme A binding pocket [chemical binding]; other site
767434002207	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
767434002208	Histidine kinase; Region: HisKA_3; pfam07730
767434002209	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
767434002210	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
767434002211	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434002212	active site
767434002213	phosphorylation site [posttranslational modification]
767434002214	intermolecular recognition site; other site
767434002215	dimerization interface [polypeptide binding]; other site
767434002216	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
767434002217	dimerization interface [polypeptide binding]; other site
767434002218	DNA binding residues [nucleotide binding]
767434002219	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
767434002220	hydrophobic ligand binding site; other site
767434002221	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
767434002222	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
767434002223	Walker A/P-loop; other site
767434002224	ATP binding site [chemical binding]; other site
767434002225	Q-loop/lid; other site
767434002226	ABC transporter signature motif; other site
767434002227	Walker B; other site
767434002228	D-loop; other site
767434002229	H-loop/switch region; other site
767434002230	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
767434002231	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
767434002232	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
767434002233	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; pfam09678
767434002234	Protein of unknown function (DUF461); Region: DUF461; pfam04314
767434002235	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
767434002236	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
767434002237	Cu(I) binding site [ion binding]; other site
767434002238	Protein of unknown function (DUF423); Region: DUF423; pfam04241
767434002239	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4877
767434002240	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
767434002241	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_2; cd03402
767434002242	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
767434002243	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434002244	ATP-grasp domain; Region: ATP-grasp; pfam02222
767434002245	arginyl-tRNA-protein transferase; Provisional; Region: PRK01305
767434002246	Arginine-tRNA-protein transferase, N terminus; Region: ATE_N; pfam04376
767434002247	Arginine-tRNA-protein transferase, C terminus; Region: ATE_C; pfam04377
767434002248	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
767434002249	Acyl-CoA thioesterase [Lipid metabolism]; Region: TesB; COG1946
767434002250	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
767434002251	active site
767434002252	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
767434002253	catalytic triad [active]
767434002254	dimer interface [polypeptide binding]; other site
767434002255	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
767434002256	amidase catalytic site [active]
767434002257	Zn binding residues [ion binding]; other site
767434002258	substrate binding site [chemical binding]; other site
767434002259	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
767434002260	PGAP1-like protein; Region: PGAP1; pfam07819
767434002261	Serine hydrolase; Region: Ser_hydrolase; cl17834
767434002262	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
767434002263	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
767434002264	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
767434002265	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434002266	S-adenosylmethionine binding site [chemical binding]; other site
767434002267	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
767434002268	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
767434002269	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
767434002270	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
767434002271	ATP-dependent helicase HrpA; Region: DEAH_box_HrpA; TIGR01967
767434002272	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
767434002273	ATP binding site [chemical binding]; other site
767434002274	putative Mg++ binding site [ion binding]; other site
767434002275	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
767434002276	nucleotide binding region [chemical binding]; other site
767434002277	ATP-binding site [chemical binding]; other site
767434002278	Helicase associated domain (HA2); Region: HA2; pfam04408
767434002279	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
767434002280	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
767434002281	HD domain; Region: HD_4; pfam13328
767434002282	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
767434002283	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
767434002284	synthetase active site [active]
767434002285	NTP binding site [chemical binding]; other site
767434002286	metal binding site [ion binding]; metal-binding site
767434002287	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
767434002288	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
767434002289	NADH(P)-binding; Region: NAD_binding_10; pfam13460
767434002290	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434002291	penicillin-binding protein 1B; Region: PBP_1b; TIGR02071
767434002292	Transglycosylase; Region: Transgly; pfam00912
767434002293	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
767434002294	TPR repeat; Region: TPR_11; pfam13414
767434002295	prephenate dehydrogenase; Provisional; Region: PRK08818
767434002296	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
767434002297	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
767434002298	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434002299	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434002300	metal binding site [ion binding]; metal-binding site
767434002301	active site
767434002302	I-site; other site
767434002303	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
767434002304	CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cl17460
767434002305	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
767434002306	putative acyltransferase; Provisional; Region: PRK05790
767434002307	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
767434002308	dimer interface [polypeptide binding]; other site
767434002309	active site
767434002310	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
767434002311	TMAO/DMSO reductase; Reviewed; Region: PRK05363
767434002312	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
767434002313	Moco binding site; other site
767434002314	metal coordination site [ion binding]; other site
767434002315	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
767434002316	Ligand Binding Site [chemical binding]; other site
767434002317	Transcriptional regulators [Transcription]; Region: FadR; COG2186
767434002318	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
767434002319	DNA-binding site [nucleotide binding]; DNA binding site
767434002320	FCD domain; Region: FCD; pfam07729
767434002321	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434002322	putative substrate translocation pore; other site
767434002323	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
767434002324	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
767434002325	HlyD family secretion protein; Region: HlyD_3; pfam13437
767434002326	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
767434002327	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
767434002328	Ligand Binding Site [chemical binding]; other site
767434002329	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
767434002330	ligand binding site [chemical binding]; other site
767434002331	flexible hinge region; other site
767434002332	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
767434002333	putative switch regulator; other site
767434002334	non-specific DNA interactions [nucleotide binding]; other site
767434002335	DNA binding site [nucleotide binding]
767434002336	sequence specific DNA binding site [nucleotide binding]; other site
767434002337	putative cAMP binding site [chemical binding]; other site
767434002338	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
767434002339	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
767434002340	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
767434002341	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
767434002342	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
767434002343	dimerization interface [polypeptide binding]; other site
767434002344	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Region: GlcNAc_2-epim; pfam07221
767434002345	putative active cleft [active]
767434002346	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
767434002347	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
767434002348	motif II; other site
767434002349	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
767434002350	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497
767434002351	Protein of unknown function, DUF482; Region: DUF482; pfam04339
767434002352	Predicted protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: COG3531
767434002353	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
767434002354	catalytic residues [active]
767434002355	thioredoxin reductase; Provisional; Region: PRK10262
767434002356	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
767434002357	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
767434002358	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
767434002359	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
767434002360	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
767434002361	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
767434002362	putative deacylase active site [active]
767434002363	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
767434002364	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
767434002365	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
767434002366	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
767434002367	dimer interface [polypeptide binding]; other site
767434002368	FMN binding site [chemical binding]; other site
767434002369	NADPH bind site [chemical binding]; other site
767434002370	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
767434002371	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
767434002372	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
767434002373	Methyltransferase domain; Region: Methyltransf_23; pfam13489
767434002374	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434002375	S-adenosylmethionine binding site [chemical binding]; other site
767434002376	exonuclease subunit SbcD; Provisional; Region: PRK10966
767434002377	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
767434002378	active site
767434002379	metal binding site [ion binding]; metal-binding site
767434002380	DNA binding site [nucleotide binding]
767434002381	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
767434002382	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434002383	AAA domain; Region: AAA_23; pfam13476
767434002384	Walker A/P-loop; other site
767434002385	ATP binding site [chemical binding]; other site
767434002386	Q-loop/lid; other site
767434002387	exonuclease subunit SbcC; Provisional; Region: PRK10246
767434002388	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434002389	ABC transporter signature motif; other site
767434002390	Walker B; other site
767434002391	D-loop; other site
767434002392	H-loop/switch region; other site
767434002393	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
767434002394	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
767434002395	Trp docking motif [polypeptide binding]; other site
767434002396	putative active site [active]
767434002397	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434002398	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434002399	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
767434002400	dimerization interface [polypeptide binding]; other site
767434002401	glutaredoxin 2; Provisional; Region: PRK10387
767434002402	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
767434002403	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
767434002404	N-terminal domain interface [polypeptide binding]; other site
767434002405	dimer interface [polypeptide binding]; other site
767434002406	substrate binding pocket (H-site) [chemical binding]; other site
767434002407	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
767434002408	non-specific DNA binding site [nucleotide binding]; other site
767434002409	salt bridge; other site
767434002410	sequence-specific DNA binding site [nucleotide binding]; other site
767434002411	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
767434002412	dimer interface [polypeptide binding]; other site
767434002413	ligand binding site [chemical binding]; other site
767434002414	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
767434002415	dimer interface [polypeptide binding]; other site
767434002416	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
767434002417	putative CheW interface [polypeptide binding]; other site
767434002418	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
767434002419	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
767434002420	16S RNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; Region: RsmC; COG2813
767434002421	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
767434002422	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
767434002423	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
767434002424	active site
767434002425	uracil binding [chemical binding]; other site
767434002426	epoxyqueuosine reductase; Region: TIGR00276
767434002427	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
767434002428	Uncharacterized conserved protein [Function unknown]; Region: COG0062
767434002429	putative carbohydrate kinase; Provisional; Region: PRK10565
767434002430	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
767434002431	putative substrate binding site [chemical binding]; other site
767434002432	putative ATP binding site [chemical binding]; other site
767434002433	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
767434002434	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; pfam03349
767434002435	3-hydroxyanthranilate 3,4-dioxygenase; Provisional; Region: PRK13264
767434002436	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
767434002437	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
767434002438	homodimer interface [polypeptide binding]; other site
767434002439	oligonucleotide binding site [chemical binding]; other site
767434002440	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
767434002441	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
767434002442	RNA binding surface [nucleotide binding]; other site
767434002443	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
767434002444	active site
767434002445	PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH  (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme.  DCoH stimulates gene expression by...; Region: PCD_DCoH_subfamily_a; cd00913
767434002446	aromatic arch; other site
767434002447	DCoH dimer interaction site [polypeptide binding]; other site
767434002448	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
767434002449	DCoH tetramer interaction site [polypeptide binding]; other site
767434002450	substrate binding site [chemical binding]; other site
767434002451	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
767434002452	IscR-regulated protein YhgI; Region: YhgI_GntY; TIGR03341
767434002453	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
767434002454	Cytochrome c553 [Energy production and conversion]; Region: COG2863
767434002455	Cytochrome c553 [Energy production and conversion]; Region: COG2863
767434002456	Uncharacterized homolog of PrgY (pheromone shutdown protein) [Function unknown]; Region: COG1916
767434002457	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
767434002458	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
767434002459	putative active site; other site
767434002460	catalytic triad [active]
767434002461	putative dimer interface [polypeptide binding]; other site
767434002462	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
767434002463	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
767434002464	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
767434002465	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434002466	Walker A/P-loop; other site
767434002467	ATP binding site [chemical binding]; other site
767434002468	Q-loop/lid; other site
767434002469	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
767434002470	ABC transporter; Region: ABC_tran_2; pfam12848
767434002471	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
767434002472	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4255
767434002473	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
767434002474	DHH family; Region: DHH; pfam01368
767434002475	DHHA1 domain; Region: DHHA1; pfam02272
767434002476	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
767434002477	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
767434002478	PAS domain; Region: PAS_9; pfam13426
767434002479	putative active site [active]
767434002480	heme pocket [chemical binding]; other site
767434002481	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434002482	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434002483	metal binding site [ion binding]; metal-binding site
767434002484	active site
767434002485	I-site; other site
767434002486	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
767434002487	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
767434002488	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
767434002489	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
767434002490	ATP binding site [chemical binding]; other site
767434002491	putative Mg++ binding site [ion binding]; other site
767434002492	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
767434002493	nucleotide binding region [chemical binding]; other site
767434002494	ATP-binding site [chemical binding]; other site
767434002495	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
767434002496	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
767434002497	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
767434002498	Outer membrane lipoprotein Slp family; Region: Slp; cl01164
767434002499	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
767434002500	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
767434002501	EamA-like transporter family; Region: EamA; pfam00892
767434002502	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
767434002503	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
767434002504	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
767434002505	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
767434002506	FAD binding pocket [chemical binding]; other site
767434002507	FAD binding motif [chemical binding]; other site
767434002508	phosphate binding motif [ion binding]; other site
767434002509	NAD binding pocket [chemical binding]; other site
767434002510	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cl17326
767434002511	putative DNA binding helix; other site
767434002512	Predicted transcriptional regulators [Transcription]; Region: COG1695
767434002513	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
767434002514	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
767434002515	EamA-like transporter family; Region: EamA; pfam00892
767434002516	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
767434002517	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434002518	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
767434002519	Walker A/P-loop; other site
767434002520	ATP binding site [chemical binding]; other site
767434002521	Q-loop/lid; other site
767434002522	ABC transporter signature motif; other site
767434002523	Walker B; other site
767434002524	D-loop; other site
767434002525	H-loop/switch region; other site
767434002526	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434002527	S-adenosylmethionine binding site [chemical binding]; other site
767434002528	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; Region: Pro_isomerase; pfam00160
767434002529	active site
767434002530	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
767434002531	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
767434002532	dimerization interface [polypeptide binding]; other site
767434002533	ligand binding site [chemical binding]; other site
767434002534	NADP binding site [chemical binding]; other site
767434002535	catalytic site [active]
767434002536	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
767434002537	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
767434002538	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
767434002539	FimV C-terminal domain; Region: FimV_Cterm; TIGR03504
767434002540	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
767434002541	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
767434002542	dimerization interface 3.5A [polypeptide binding]; other site
767434002543	active site
767434002544	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
767434002545	active site
767434002546	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
767434002547	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434002548	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
767434002549	dimerization interface [polypeptide binding]; other site
767434002550	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
767434002551	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
767434002552	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434002553	catalytic residue [active]
767434002554	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
767434002555	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
767434002556	substrate binding site [chemical binding]; other site
767434002557	active site
767434002558	catalytic residues [active]
767434002559	heterodimer interface [polypeptide binding]; other site
767434002560	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
767434002561	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
767434002562	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
767434002563	AMIN domain; Region: AMIN; pfam11741
767434002564	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
767434002565	active site
767434002566	metal binding site [ion binding]; metal-binding site
767434002567	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
767434002568	active site
767434002569	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_2; cd03814
767434002570	Domain of unknown function (DUF4399); Region: DUF4399; pfam14347
767434002571	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
767434002572	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
767434002573	active site
767434002574	HIGH motif; other site
767434002575	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
767434002576	active site
767434002577	KMSKS motif; other site
767434002578	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
767434002579	metal binding site 2 [ion binding]; metal-binding site
767434002580	putative DNA binding helix; other site
767434002581	metal binding site 1 [ion binding]; metal-binding site
767434002582	dimer interface [polypeptide binding]; other site
767434002583	structural Zn2+ binding site [ion binding]; other site
767434002584	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
767434002585	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
767434002586	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
767434002587	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
767434002588	active site
767434002589	substrate binding site [chemical binding]; other site
767434002590	cosubstrate binding site; other site
767434002591	catalytic site [active]
767434002592	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
767434002593	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
767434002594	dimerization interface [polypeptide binding]; other site
767434002595	putative ATP binding site [chemical binding]; other site
767434002596	Uncharacterized protein conserved in bacteria (DUF2066); Region: DUF2066; pfam09839
767434002597	Domain of unknown function DUF20; Region: UPF0118; pfam01594
767434002598	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
767434002599	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
767434002600	DnaA regulatory inactivator Hda; Region: DnaA_homol_Hda; TIGR03420
767434002601	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
767434002602	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
767434002603	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
767434002604	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
767434002605	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
767434002606	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
767434002607	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
767434002608	Protein export membrane protein; Region: SecD_SecF; pfam02355
767434002609	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
767434002610	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434002611	active site
767434002612	phosphorylation site [posttranslational modification]
767434002613	intermolecular recognition site; other site
767434002614	dimerization interface [polypeptide binding]; other site
767434002615	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
767434002616	DNA binding residues [nucleotide binding]
767434002617	dimerization interface [polypeptide binding]; other site
767434002618	Carbohydrate-selective porin, OprB family; Region: OprB; cl17816
767434002619	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434002620	cytochrome c-550; Provisional; Region: psbV; cl17239
767434002621	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434002622	Cytochrome c; Region: Cytochrom_C; pfam00034
767434002623	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
767434002624	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
767434002625	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
767434002626	Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318
767434002627	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434002628	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434002629	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
767434002630	putative effector binding pocket; other site
767434002631	dimerization interface [polypeptide binding]; other site
767434002632	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
767434002633	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
767434002634	Uncharacterized protein containing double-stranded beta helix domain [Function unknown]; Region: COG4297
767434002635	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
767434002636	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
767434002637	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
767434002638	active site
767434002639	DNA binding site [nucleotide binding]
767434002640	Int/Topo IB signature motif; other site
767434002641	Domain of unknown function (DUF4224); Region: DUF4224; pfam13986
767434002642	HNH endonuclease; Region: HNH_3; pfam13392
767434002643	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
767434002644	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
767434002645	dimer interface [polypeptide binding]; other site
767434002646	ssDNA binding site [nucleotide binding]; other site
767434002647	tetramer (dimer of dimers) interface [polypeptide binding]; other site
767434002648	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434002649	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434002650	metal binding site [ion binding]; metal-binding site
767434002651	active site
767434002652	I-site; other site
767434002653	Domain of unknown function (DUF4415); Region: DUF4415; cl01401
767434002654	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
767434002655	non-specific DNA binding site [nucleotide binding]; other site
767434002656	salt bridge; other site
767434002657	sequence-specific DNA binding site [nucleotide binding]; other site
767434002658	Predicted transcriptional regulator [Transcription]; Region: COG2932
767434002659	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
767434002660	Catalytic site [active]
767434002661	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
767434002662	Protein of unknown function (DUF1376); Region: DUF1376; pfam07120
767434002663	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
767434002664	VRR-NUC domain; Region: VRR_NUC; pfam08774
767434002665	glutaminyl-tRNA synthetase; Region: glnS; TIGR00440
767434002666	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
767434002667	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
767434002668	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; cl10713
767434002669	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
767434002670	catalytic residues [active]
767434002671	Phage DNA packaging protein Nu1; Region: Phage_Nu1; cl01720
767434002672	Phage terminase large subunit (GpA); Region: Terminase_GpA; pfam05876
767434002673	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
767434002674	Phage portal protein, lambda family; Region: Phage_portal_2; pfam05136
767434002675	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
767434002676	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
767434002677	tandem repeat interface [polypeptide binding]; other site
767434002678	oligomer interface [polypeptide binding]; other site
767434002679	active site residues [active]
767434002680	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
767434002681	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
767434002682	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; cl05094
767434002683	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
767434002684	Phage-related baseplate assembly protein; Region: Phage_base_V; cl17812
767434002685	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
767434002686	Baseplate J-like protein; Region: Baseplate_J; cl01294
767434002687	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; cl01817
767434002688	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
767434002689	Phage tail tube protein FII; Region: Phage_tube; pfam04985
767434002690	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
767434002691	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
767434002692	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
767434002693	Phage Tail Protein X; Region: Phage_tail_X; cl02088
767434002694	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
767434002695	SnoaL-like domain; Region: SnoaL_2; pfam12680
767434002696	Predicted transcriptional regulators [Transcription]; Region: COG1733
767434002697	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
767434002698	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434002699	NADH(P)-binding; Region: NAD_binding_10; pfam13460
767434002700	NAD(P) binding site [chemical binding]; other site
767434002701	active site
767434002702	Major Facilitator Superfamily; Region: MFS_1; pfam07690
767434002703	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434002704	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434002705	Sensors of blue-light using FAD; Region: BLUF; pfam04940
767434002706	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
767434002707	Sensors of blue-light using FAD; Region: BLUF; pfam04940
767434002708	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
767434002709	Protein of unknown function (DUF3325); Region: DUF3325; pfam11804
767434002710	PepSY-associated TM helix; Region: PepSY_TM_3; pfam13706
767434002711	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
767434002712	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
767434002713	Transcriptional regulators [Transcription]; Region: FadR; COG2186
767434002714	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
767434002715	DNA-binding site [nucleotide binding]; DNA binding site
767434002716	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
767434002717	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
767434002718	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434002719	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434002720	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
767434002721	non-specific DNA binding site [nucleotide binding]; other site
767434002722	salt bridge; other site
767434002723	sequence-specific DNA binding site [nucleotide binding]; other site
767434002724	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_31; cd04690
767434002725	nudix motif; other site
767434002726	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
767434002727	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
767434002728	tetramer interface [polypeptide binding]; other site
767434002729	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434002730	catalytic residue [active]
767434002731	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434002732	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434002733	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
767434002734	DNA-binding site [nucleotide binding]; DNA binding site
767434002735	transcriptional regulator protein; Region: phnR; TIGR03337
767434002736	UTRA domain; Region: UTRA; pfam07702
767434002737	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
767434002738	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
767434002739	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
767434002740	active site residue [active]
767434002741	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
767434002742	active site residue [active]
767434002743	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
767434002744	active site
767434002745	ATP binding site [chemical binding]; other site
767434002746	substrate binding site [chemical binding]; other site
767434002747	NMT1/THI5 like; Region: NMT1; pfam09084
767434002748	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
767434002749	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
767434002750	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434002751	N-terminal plug; other site
767434002752	ligand-binding site [chemical binding]; other site
767434002753	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434002754	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434002755	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
767434002756	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434002757	putative substrate translocation pore; other site
767434002758	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
767434002759	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
767434002760	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
767434002761	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
767434002762	catalytic residues [active]
767434002763	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
767434002764	Homoserine acetyltransferase [Amino acid transport and metabolism]; Region: MET2; COG2021
767434002765	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434002766	TPR repeat; Region: TPR_11; pfam13414
767434002767	binding surface
767434002768	TPR motif; other site
767434002769	Cytochrome C biogenesis protein; Region: CcmH; pfam03918
767434002770	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
767434002771	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
767434002772	catalytic residues [active]
767434002773	central insert; other site
767434002774	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
767434002775	CcmE; Region: CcmE; cl00994
767434002776	heme exporter protein CcmD; Region: cytochro_ccmD; TIGR03141
767434002777	heme exporter protein CcmC; Region: ccmC; TIGR01191
767434002778	CcmB protein; Region: CcmB; cl17444
767434002779	ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones]; Region: CcmA; COG4133
767434002780	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434002781	Walker A/P-loop; other site
767434002782	ATP binding site [chemical binding]; other site
767434002783	Q-loop/lid; other site
767434002784	ABC transporter signature motif; other site
767434002785	Walker B; other site
767434002786	D-loop; other site
767434002787	H-loop/switch region; other site
767434002788	Protein of unknown function (DUF3293); Region: DUF3293; pfam11697
767434002789	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
767434002790	RNA polymerase sigma factor AlgU; Provisional; Region: algU; PRK11923
767434002791	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
767434002792	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
767434002793	DNA binding residues [nucleotide binding]
767434002794	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
767434002795	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
767434002796	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
767434002797	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
767434002798	protein binding site [polypeptide binding]; other site
767434002799	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
767434002800	GTP-binding protein LepA; Provisional; Region: PRK05433
767434002801	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
767434002802	G1 box; other site
767434002803	putative GEF interaction site [polypeptide binding]; other site
767434002804	GTP/Mg2+ binding site [chemical binding]; other site
767434002805	Switch I region; other site
767434002806	G2 box; other site
767434002807	G3 box; other site
767434002808	Switch II region; other site
767434002809	G4 box; other site
767434002810	G5 box; other site
767434002811	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
767434002812	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
767434002813	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
767434002814	signal peptidase I; Provisional; Region: PRK10861
767434002815	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
767434002816	Catalytic site [active]
767434002817	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
767434002818	ribonuclease III; Reviewed; Region: rnc; PRK00102
767434002819	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
767434002820	dimerization interface [polypeptide binding]; other site
767434002821	active site
767434002822	metal binding site [ion binding]; metal-binding site
767434002823	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
767434002824	dsRNA binding site [nucleotide binding]; other site
767434002825	GTPase Era; Reviewed; Region: era; PRK00089
767434002826	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
767434002827	G1 box; other site
767434002828	GTP/Mg2+ binding site [chemical binding]; other site
767434002829	Switch I region; other site
767434002830	G2 box; other site
767434002831	Switch II region; other site
767434002832	G3 box; other site
767434002833	G4 box; other site
767434002834	G5 box; other site
767434002835	KH domain; Region: KH_2; pfam07650
767434002836	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
767434002837	Recombination protein O N terminal; Region: RecO_N; pfam11967
767434002838	Recombination protein O C terminal; Region: RecO_C; pfam02565
767434002839	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
767434002840	Helix-turn-helix domain; Region: HTH_18; pfam12833
767434002841	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
767434002842	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
767434002843	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
767434002844	DNA binding site [nucleotide binding]
767434002845	active site
767434002846	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
767434002847	catalytic motif [active]
767434002848	Catalytic residue [active]
767434002849	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
767434002850	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
767434002851	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
767434002852	Walker A/P-loop; other site
767434002853	ATP binding site [chemical binding]; other site
767434002854	Q-loop/lid; other site
767434002855	ABC transporter signature motif; other site
767434002856	Walker B; other site
767434002857	D-loop; other site
767434002858	H-loop/switch region; other site
767434002859	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
767434002860	DNA-binding site [nucleotide binding]; DNA binding site
767434002861	TraB family; Region: TraB; cl12050
767434002862	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
767434002863	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
767434002864	FAD binding domain; Region: FAD_binding_4; pfam01565
767434002865	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
767434002866	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
767434002867	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
767434002868	quinone interaction residues [chemical binding]; other site
767434002869	active site
767434002870	catalytic residues [active]
767434002871	FMN binding site [chemical binding]; other site
767434002872	substrate binding site [chemical binding]; other site
767434002873	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4994
767434002874	aldehyde dehydrogenase family 7 member; Region: PLN02315
767434002875	NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B; Region: ALDH_F7_AASADH; cd07130
767434002876	tetrameric interface [polypeptide binding]; other site
767434002877	NAD binding site [chemical binding]; other site
767434002878	catalytic residues [active]
767434002879	ribosome maturation protein RimP; Reviewed; Region: PRK00092
767434002880	Sm and related proteins; Region: Sm_like; cl00259
767434002881	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
767434002882	putative oligomer interface [polypeptide binding]; other site
767434002883	putative RNA binding site [nucleotide binding]; other site
767434002884	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
767434002885	NusA N-terminal domain; Region: NusA_N; pfam08529
767434002886	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
767434002887	RNA binding site [nucleotide binding]; other site
767434002888	homodimer interface [polypeptide binding]; other site
767434002889	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
767434002890	G-X-X-G motif; other site
767434002891	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
767434002892	G-X-X-G motif; other site
767434002893	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
767434002894	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
767434002895	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
767434002896	translation initiation factor IF-2; Region: IF-2; TIGR00487
767434002897	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
767434002898	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
767434002899	G1 box; other site
767434002900	putative GEF interaction site [polypeptide binding]; other site
767434002901	GTP/Mg2+ binding site [chemical binding]; other site
767434002902	Switch I region; other site
767434002903	G2 box; other site
767434002904	G3 box; other site
767434002905	Switch II region; other site
767434002906	G4 box; other site
767434002907	G5 box; other site
767434002908	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
767434002909	Translation-initiation factor 2; Region: IF-2; pfam11987
767434002910	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
767434002911	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
767434002912	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK04642
767434002913	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
767434002914	RNA binding site [nucleotide binding]; other site
767434002915	active site
767434002916	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
767434002917	16S/18S rRNA binding site [nucleotide binding]; other site
767434002918	S13e-L30e interaction site [polypeptide binding]; other site
767434002919	25S rRNA binding site [nucleotide binding]; other site
767434002920	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
767434002921	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
767434002922	RNase E interface [polypeptide binding]; other site
767434002923	trimer interface [polypeptide binding]; other site
767434002924	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
767434002925	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
767434002926	RNase E interface [polypeptide binding]; other site
767434002927	trimer interface [polypeptide binding]; other site
767434002928	active site
767434002929	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
767434002930	putative nucleic acid binding region [nucleotide binding]; other site
767434002931	G-X-X-G motif; other site
767434002932	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
767434002933	RNA binding site [nucleotide binding]; other site
767434002934	domain interface; other site
767434002935	Protein of unknown function (DUF3037); Region: DUF3037; pfam11236
767434002936	Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E); Region: PHA_synth_III_E; cl09914
767434002937	poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit; Region: PHA_synth_III_C; TIGR01836
767434002938	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
767434002939	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
767434002940	GtrA-like protein; Region: GtrA; pfam04138
767434002941	DNA gyrase subunit A; Validated; Region: PRK05560
767434002942	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
767434002943	CAP-like domain; other site
767434002944	active site
767434002945	primary dimer interface [polypeptide binding]; other site
767434002946	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
767434002947	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
767434002948	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
767434002949	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
767434002950	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
767434002951	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
767434002952	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
767434002953	sequence-specific DNA binding site [nucleotide binding]; other site
767434002954	salt bridge; other site
767434002955	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
767434002956	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434002957	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
767434002958	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
767434002959	putative dimer interface [polypeptide binding]; other site
767434002960	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
767434002961	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
767434002962	HSP70 interaction site [polypeptide binding]; other site
767434002963	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
767434002964	substrate binding site [polypeptide binding]; other site
767434002965	dimer interface [polypeptide binding]; other site
767434002966	Predicted transcriptional regulators [Transcription]; Region: COG1733
767434002967	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
767434002968	Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltE; COG3967
767434002969	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434002970	NAD(P) binding site [chemical binding]; other site
767434002971	active site
767434002972	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
767434002973	putative pectinesterase; Region: PLN02432; cl01911
767434002974	FAD binding domain; Region: FAD_binding_3; pfam01494
767434002975	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
767434002976	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
767434002977	Transcriptional regulator [Transcription]; Region: IclR; COG1414
767434002978	Bacterial transcriptional regulator; Region: IclR; pfam01614
767434002979	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
767434002980	Zn binding site [ion binding]; other site
767434002981	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
767434002982	HI0933-like protein; Region: HI0933_like; pfam03486
767434002983	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
767434002984	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
767434002985	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
767434002986	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
767434002987	Predicted aminopeptidase (DUF2265); Region: DUF2265; pfam10023
767434002988	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
767434002989	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
767434002990	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
767434002991	active site
767434002992	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
767434002993	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
767434002994	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
767434002995	dimer interface [polypeptide binding]; other site
767434002996	conserved gate region; other site
767434002997	ABC-ATPase subunit interface; other site
767434002998	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
767434002999	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
767434003000	Walker A/P-loop; other site
767434003001	ATP binding site [chemical binding]; other site
767434003002	Q-loop/lid; other site
767434003003	ABC transporter signature motif; other site
767434003004	Walker B; other site
767434003005	D-loop; other site
767434003006	H-loop/switch region; other site
767434003007	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
767434003008	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
767434003009	catalytic residues [active]
767434003010	dimer interface [polypeptide binding]; other site
767434003011	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
767434003012	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
767434003013	dimer interface [polypeptide binding]; other site
767434003014	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434003015	catalytic residue [active]
767434003016	Homoserine acetyltransferase [Amino acid transport and metabolism]; Region: MET2; COG2021
767434003017	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
767434003018	O-succinylhomoserine (thiol)-lyase; Region: O_succ_thio_ly; TIGR02080
767434003019	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
767434003020	homodimer interface [polypeptide binding]; other site
767434003021	substrate-cofactor binding pocket; other site
767434003022	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434003023	catalytic residue [active]
767434003024	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
767434003025	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
767434003026	Fusaric acid resistance protein family; Region: FUSC; pfam04632
767434003027	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
767434003028	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
767434003029	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
767434003030	HlyD family secretion protein; Region: HlyD_3; pfam13437
767434003031	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
767434003032	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
767434003033	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
767434003034	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
767434003035	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
767434003036	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419
767434003037	putative active site [active]
767434003038	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
767434003039	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434003040	Walker A/P-loop; other site
767434003041	ATP binding site [chemical binding]; other site
767434003042	Q-loop/lid; other site
767434003043	ABC transporter signature motif; other site
767434003044	Walker B; other site
767434003045	D-loop; other site
767434003046	H-loop/switch region; other site
767434003047	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
767434003048	HlyD family secretion protein; Region: HlyD_3; pfam13437
767434003049	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
767434003050	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
767434003051	E3 interaction surface; other site
767434003052	lipoyl attachment site [posttranslational modification]; other site
767434003053	e3 binding domain; Region: E3_binding; pfam02817
767434003054	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
767434003055	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
767434003056	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
767434003057	alpha subunit interface [polypeptide binding]; other site
767434003058	TPP binding site [chemical binding]; other site
767434003059	heterodimer interface [polypeptide binding]; other site
767434003060	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
767434003061	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
767434003062	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
767434003063	TPP-binding site [chemical binding]; other site
767434003064	tetramer interface [polypeptide binding]; other site
767434003065	heterodimer interface [polypeptide binding]; other site
767434003066	phosphorylation loop region [posttranslational modification]
767434003067	Tryptophan 2,3-dioxygenase; Region: Trp_dioxygenase; cl03994
767434003068	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
767434003069	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
767434003070	ATP binding site [chemical binding]; other site
767434003071	putative Mg++ binding site [ion binding]; other site
767434003072	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
767434003073	nucleotide binding region [chemical binding]; other site
767434003074	ATP-binding site [chemical binding]; other site
767434003075	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
767434003076	HRDC domain; Region: HRDC; pfam00570
767434003077	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
767434003078	MPT binding site; other site
767434003079	trimer interface [polypeptide binding]; other site
767434003080	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434003081	S-adenosylmethionine binding site [chemical binding]; other site
767434003082	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434003083	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434003084	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_7; cd08476
767434003085	putative effector binding pocket; other site
767434003086	putative dimerization interface [polypeptide binding]; other site
767434003087	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
767434003088	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
767434003089	putative NAD(P) binding site [chemical binding]; other site
767434003090	dimer interface [polypeptide binding]; other site
767434003091	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
767434003092	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
767434003093	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
767434003094	G1 box; other site
767434003095	putative GEF interaction site [polypeptide binding]; other site
767434003096	GTP/Mg2+ binding site [chemical binding]; other site
767434003097	Switch I region; other site
767434003098	G2 box; other site
767434003099	G3 box; other site
767434003100	Switch II region; other site
767434003101	G4 box; other site
767434003102	G5 box; other site
767434003103	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
767434003104	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
767434003105	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
767434003106	active site
767434003107	Bacterial protein of unknown function (DUF937); Region: DUF937; cl01528
767434003108	Predicted membrane protein [Function unknown]; Region: COG2261
767434003109	malate dehydrogenase; Provisional; Region: PRK05442
767434003110	Chloroplast-like malate dehydrogenases; Region: MDH_choloroplast_like; cd01338
767434003111	NAD(P) binding site [chemical binding]; other site
767434003112	dimer interface [polypeptide binding]; other site
767434003113	malate binding site [chemical binding]; other site
767434003114	progesterone 5-beta-reductase-like proteins (5beta-POR), atypical (a) SDRs; Region: 5beta-POR_like_SDR_a; cd08948
767434003115	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
767434003116	NAD(P) binding site [chemical binding]; other site
767434003117	active site
767434003118	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434003119	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434003120	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
767434003121	dimerization interface [polypeptide binding]; other site
767434003122	Alginate lyase; Region: Alginate_lyase; pfam05426
767434003123	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
767434003124	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
767434003125	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
767434003126	ligand binding site [chemical binding]; other site
767434003127	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
767434003128	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
767434003129	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
767434003130	ligand binding site [chemical binding]; other site
767434003131	integral membrane protein, YjbE family; Region: R_switched_YjbE; TIGR03717
767434003132	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
767434003133	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
767434003134	RNA binding surface [nucleotide binding]; other site
767434003135	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
767434003136	active site
767434003137	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
767434003138	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
767434003139	substrate-cofactor binding pocket; other site
767434003140	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434003141	catalytic residue [active]
767434003142	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
767434003143	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
767434003144	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
767434003145	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
767434003146	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
767434003147	ligand binding site [chemical binding]; other site
767434003148	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
767434003149	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
767434003150	NAD(P) binding site [chemical binding]; other site
767434003151	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
767434003152	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
767434003153	bacterial Hfq-like; Region: Hfq; cd01716
767434003154	hexamer interface [polypeptide binding]; other site
767434003155	Sm1 motif; other site
767434003156	RNA binding site [nucleotide binding]; other site
767434003157	Sm2 motif; other site
767434003158	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
767434003159	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
767434003160	HflX GTPase family; Region: HflX; cd01878
767434003161	G1 box; other site
767434003162	GTP/Mg2+ binding site [chemical binding]; other site
767434003163	Switch I region; other site
767434003164	G2 box; other site
767434003165	G3 box; other site
767434003166	Switch II region; other site
767434003167	G4 box; other site
767434003168	G5 box; other site
767434003169	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
767434003170	active site
767434003171	8-oxo-dGMP binding site [chemical binding]; other site
767434003172	hypothetical protein; Provisional; Region: PRK08999
767434003173	nudix motif; other site
767434003174	metal binding site [ion binding]; metal-binding site
767434003175	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
767434003176	thiamine phosphate binding site [chemical binding]; other site
767434003177	active site
767434003178	pyrophosphate binding site [ion binding]; other site
767434003179	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
767434003180	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
767434003181	CoA-binding site [chemical binding]; other site
767434003182	ATP-binding [chemical binding]; other site
767434003183	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
767434003184	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
767434003185	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
767434003186	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
767434003187	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
767434003188	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
767434003189	type IV-A pilus assembly ATPase PilB; Region: type_IV_pilB; TIGR02538
767434003190	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
767434003191	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
767434003192	Walker A motif; other site
767434003193	ATP binding site [chemical binding]; other site
767434003194	Walker B motif; other site
767434003195	helicase 45; Provisional; Region: PTZ00424
767434003196	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
767434003197	ATP binding site [chemical binding]; other site
767434003198	Mg++ binding site [ion binding]; other site
767434003199	motif III; other site
767434003200	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
767434003201	nucleotide binding region [chemical binding]; other site
767434003202	ATP-binding site [chemical binding]; other site
767434003203	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
767434003204	putative RNA binding site [nucleotide binding]; other site
767434003205	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
767434003206	clavulanic acid dehydrogenase (CAD), classical (c) SDR; Region: CAD_SDR_c; cd08934
767434003207	NADP binding site [chemical binding]; other site
767434003208	homotetramer interface [polypeptide binding]; other site
767434003209	homodimer interface [polypeptide binding]; other site
767434003210	active site
767434003211	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
767434003212	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
767434003213	helicase 45; Provisional; Region: PTZ00424
767434003214	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
767434003215	ATP binding site [chemical binding]; other site
767434003216	Mg++ binding site [ion binding]; other site
767434003217	motif III; other site
767434003218	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
767434003219	nucleotide binding region [chemical binding]; other site
767434003220	ATP-binding site [chemical binding]; other site
767434003221	putative sialic acid transporter; Region: 2A0112; TIGR00891
767434003222	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434003223	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
767434003224	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
767434003225	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
767434003226	NlpC/P60 family; Region: NLPC_P60; pfam00877
767434003227	Protein of unknown function (DUF489); Region: DUF489; cl01097
767434003228	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
767434003229	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
767434003230	Ligand Binding Site [chemical binding]; other site
767434003231	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
767434003232	nudix motif; other site
767434003233	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
767434003234	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
767434003235	Clp amino terminal domain; Region: Clp_N; pfam02861
767434003236	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434003237	Walker A motif; other site
767434003238	ATP binding site [chemical binding]; other site
767434003239	Walker B motif; other site
767434003240	arginine finger; other site
767434003241	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434003242	Walker A motif; other site
767434003243	ATP binding site [chemical binding]; other site
767434003244	Walker B motif; other site
767434003245	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
767434003246	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
767434003247	rRNA binding site [nucleotide binding]; other site
767434003248	predicted 30S ribosome binding site; other site
767434003249	Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn); Region: PHA_gran_rgn; pfam09650
767434003250	FHA domain; Region: FHA; pfam00498
767434003251	phosphopeptide binding site; other site
767434003252	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
767434003253	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
767434003254	catalytic residue [active]
767434003255	Chorismate mutase type II; Region: CM_2; cl00693
767434003256	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
767434003257	Prephenate dehydratase; Region: PDT; pfam00800
767434003258	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
767434003259	putative L-Phe binding site [chemical binding]; other site
767434003260	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
767434003261	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
767434003262	hinge; other site
767434003263	active site
767434003264	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
767434003265	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
767434003266	Ligand binding site; other site
767434003267	oligomer interface; other site
767434003268	putative choline sulfate-utilization transcription factor; Region: chol_sulf_TF; TIGR03418
767434003269	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434003270	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
767434003271	putative effector binding pocket; other site
767434003272	dimerization interface [polypeptide binding]; other site
767434003273	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
767434003274	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
767434003275	substrate binding site [chemical binding]; other site
767434003276	catalytic Zn binding site [ion binding]; other site
767434003277	NAD binding site [chemical binding]; other site
767434003278	structural Zn binding site [ion binding]; other site
767434003279	dimer interface [polypeptide binding]; other site
767434003280	SnoaL-like domain; Region: SnoaL_2; pfam12680
767434003281	Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625
767434003282	Helix-turn-helix domain; Region: HTH_18; pfam12833
767434003283	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434003284	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
767434003285	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
767434003286	trimer interface [polypeptide binding]; other site
767434003287	YadA-like C-terminal region; Region: YadA; pfam03895
767434003288	Protein of unknown function (DUF2827); Region: DUF2827; pfam10933
767434003289	Protein of unknown function (DUF2827); Region: DUF2827; pfam10933
767434003290	Protein of unknown function (DUF2827); Region: DUF2827; pfam10933
767434003291	Gram-negative bacterial tonB protein; Region: TonB; cl10048
767434003292	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
767434003293	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
767434003294	GIY-YIG motif/motif A; other site
767434003295	active site
767434003296	catalytic site [active]
767434003297	putative DNA binding site [nucleotide binding]; other site
767434003298	metal binding site [ion binding]; metal-binding site
767434003299	UvrB/uvrC motif; Region: UVR; pfam02151
767434003300	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
767434003301	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
767434003302	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434003303	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434003304	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
767434003305	putative effector binding pocket; other site
767434003306	putative dimerization interface [polypeptide binding]; other site
767434003307	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
767434003308	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
767434003309	putative NAD(P) binding site [chemical binding]; other site
767434003310	putative substrate binding site [chemical binding]; other site
767434003311	catalytic Zn binding site [ion binding]; other site
767434003312	structural Zn binding site [ion binding]; other site
767434003313	dimer interface [polypeptide binding]; other site
767434003314	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
767434003315	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
767434003316	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
767434003317	Uncharacterized conserved protein [Function unknown]; Region: COG4925
767434003318	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
767434003319	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
767434003320	putative NAD(P) binding site [chemical binding]; other site
767434003321	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
767434003322	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434003323	putative substrate translocation pore; other site
767434003324	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434003325	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434003326	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
767434003327	putative effector binding pocket; other site
767434003328	putative dimerization interface [polypeptide binding]; other site
767434003329	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
767434003330	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
767434003331	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
767434003332	catalytic loop [active]
767434003333	iron binding site [ion binding]; other site
767434003334	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
767434003335	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
767434003336	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
767434003337	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
767434003338	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
767434003339	cytochrome c-550; Provisional; Region: psbV; cl17239
767434003340	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434003341	Cytochrome c; Region: Cytochrom_C; pfam00034
767434003342	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434003343	Cytochrome c; Region: Cytochrom_C; pfam00034
767434003344	Predicted transcriptional regulators [Transcription]; Region: COG1733
767434003345	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
767434003346	dimerization interface [polypeptide binding]; other site
767434003347	putative DNA binding site [nucleotide binding]; other site
767434003348	putative Zn2+ binding site [ion binding]; other site
767434003349	atypical (a) SDRs, subgroup 6; Region: SDR_a6; cd05267
767434003350	NADH(P)-binding; Region: NAD_binding_10; pfam13460
767434003351	putative NAD(P) binding site [chemical binding]; other site
767434003352	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
767434003353	RibD C-terminal domain; Region: RibD_C; cl17279
767434003354	RibD C-terminal domain; Region: RibD_C; cl17279
767434003355	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
767434003356	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434003357	putative substrate translocation pore; other site
767434003358	short chain dehydrogenase; Provisional; Region: PRK07060
767434003359	classical (c) SDRs; Region: SDR_c; cd05233
767434003360	NAD(P) binding site [chemical binding]; other site
767434003361	active site
767434003362	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434003363	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434003364	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
767434003365	putative effector binding pocket; other site
767434003366	putative dimerization interface [polypeptide binding]; other site
767434003367	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
767434003368	Autoinducer binding domain; Region: Autoind_bind; pfam03472
767434003369	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
767434003370	DNA binding residues [nucleotide binding]
767434003371	dimerization interface [polypeptide binding]; other site
767434003372	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
767434003373	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
767434003374	iron-sulfur cluster [ion binding]; other site
767434003375	[2Fe-2S] cluster binding site [ion binding]; other site
767434003376	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
767434003377	substrate binding pocket [chemical binding]; other site
767434003378	substrate-Mg2+ binding site; other site
767434003379	aspartate-rich region 1; other site
767434003380	aspartate-rich region 2; other site
767434003381	Cytochrome P450; Region: p450; cl12078
767434003382	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
767434003383	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
767434003384	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
767434003385	active site
767434003386	dimer interface [polypeptide binding]; other site
767434003387	motif 1; other site
767434003388	motif 2; other site
767434003389	motif 3; other site
767434003390	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
767434003391	anticodon binding site; other site
767434003392	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
767434003393	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
767434003394	substrate binding [chemical binding]; other site
767434003395	active site
767434003396	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
767434003397	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
767434003398	salt bridge; other site
767434003399	non-specific DNA binding site [nucleotide binding]; other site
767434003400	sequence-specific DNA binding site [nucleotide binding]; other site
767434003401	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
767434003402	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
767434003403	NAD(P) binding site [chemical binding]; other site
767434003404	catalytic residues [active]
767434003405	acetolactate synthase; Reviewed; Region: PRK08322
767434003406	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
767434003407	PYR/PP interface [polypeptide binding]; other site
767434003408	dimer interface [polypeptide binding]; other site
767434003409	TPP binding site [chemical binding]; other site
767434003410	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
767434003411	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
767434003412	TPP-binding site [chemical binding]; other site
767434003413	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
767434003414	catalytic motif [active]
767434003415	Zn binding site [ion binding]; other site
767434003416	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
767434003417	Glycoprotease family; Region: Peptidase_M22; pfam00814
767434003418	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
767434003419	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434003420	active site
767434003421	phosphorylation site [posttranslational modification]
767434003422	intermolecular recognition site; other site
767434003423	dimerization interface [polypeptide binding]; other site
767434003424	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
767434003425	DNA binding site [nucleotide binding]
767434003426	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434003427	dimer interface [polypeptide binding]; other site
767434003428	phosphorylation site [posttranslational modification]
767434003429	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434003430	ATP binding site [chemical binding]; other site
767434003431	Mg2+ binding site [ion binding]; other site
767434003432	G-X-G motif; other site
767434003433	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
767434003434	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
767434003435	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
767434003436	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
767434003437	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
767434003438	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
767434003439	dimerization domain swap beta strand [polypeptide binding]; other site
767434003440	regulatory protein interface [polypeptide binding]; other site
767434003441	active site
767434003442	regulatory phosphorylation site [posttranslational modification]; other site
767434003443	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
767434003444	active pocket/dimerization site; other site
767434003445	active site
767434003446	phosphorylation site [posttranslational modification]
767434003447	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
767434003448	AAA domain; Region: AAA_18; pfam13238
767434003449	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
767434003450	Hpr(Ser) kinase/phosphatase; Region: hpr-ser; TIGR00679
767434003451	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
767434003452	Hpr binding site; other site
767434003453	active site
767434003454	homohexamer subunit interaction site [polypeptide binding]; other site
767434003455	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
767434003456	30S subunit binding site; other site
767434003457	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
767434003458	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
767434003459	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
767434003460	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
767434003461	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
767434003462	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
767434003463	Walker A/P-loop; other site
767434003464	ATP binding site [chemical binding]; other site
767434003465	Q-loop/lid; other site
767434003466	ABC transporter signature motif; other site
767434003467	Walker B; other site
767434003468	D-loop; other site
767434003469	H-loop/switch region; other site
767434003470	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
767434003471	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3117; cl01200
767434003472	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
767434003473	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
767434003474	active site
767434003475	motif I; other site
767434003476	motif II; other site
767434003477	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
767434003478	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
767434003479	putative active site [active]
767434003480	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
767434003481	BolA-like protein; Region: BolA; cl00386
767434003482	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
767434003483	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
767434003484	hinge; other site
767434003485	active site
767434003486	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
767434003487	ClC chloride channel family. These protein sequences, closely related to the ClC Eric family, are putative halogen ion (Cl-, Br- and I-) transport proteins found in eubacteria. They belong to the ClC superfamily of chloride ion channels, which share a...; Region: EriC_like; cd01034
767434003488	putative ion selectivity filter; other site
767434003489	putative pore gating glutamate residue; other site
767434003490	putative H+/Cl- coupling transport residue; other site
767434003491	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
767434003492	AAA domain; Region: AAA_30; pfam13604
767434003493	Family description; Region: UvrD_C_2; pfam13538
767434003494	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
767434003495	Part of AAA domain; Region: AAA_19; pfam13245
767434003496	Family description; Region: UvrD_C_2; pfam13538
767434003497	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
767434003498	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
767434003499	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
767434003500	cobalamin biosynthesis protein CobW; Region: CobW; TIGR02475
767434003501	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
767434003502	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
767434003503	cobaltochelatase subunit CobN; Reviewed; Region: cobN; PRK05989
767434003504	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
767434003505	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
767434003506	Mg-protoporyphyrin IX chelatase; Region: chlI; CHL00081
767434003507	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434003508	Walker A motif; other site
767434003509	ATP binding site [chemical binding]; other site
767434003510	Walker B motif; other site
767434003511	arginine finger; other site
767434003512	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
767434003513	metal ion-dependent adhesion site (MIDAS); other site
767434003514	Cobalamin biosynthesis protein CbiG [Coenzyme metabolism]; Region: CbiG; COG2073
767434003515	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
767434003516	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
767434003517	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
767434003518	active site
767434003519	SAM binding site [chemical binding]; other site
767434003520	homodimer interface [polypeptide binding]; other site
767434003521	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
767434003522	active site
767434003523	SAM binding site [chemical binding]; other site
767434003524	homodimer interface [polypeptide binding]; other site
767434003525	precorrin-8X methylmutase; Reviewed; Region: cobH; PRK08285
767434003526	Precorrin-8X methylmutase; Region: CbiC; pfam02570
767434003527	precorrin-3B synthase; Region: CobG; TIGR02435
767434003528	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
767434003529	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
767434003530	active site
767434003531	putative homodimer interface [polypeptide binding]; other site
767434003532	SAM binding site [chemical binding]; other site
767434003533	Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242
767434003534	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434003535	S-adenosylmethionine binding site [chemical binding]; other site
767434003536	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
767434003537	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
767434003538	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
767434003539	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
767434003540	Diphthamide biosynthesis methyltransferase [Translation, ribosomal structure and biogenesis]; Region: DPH5; COG1798
767434003541	active site
767434003542	SAM binding site [chemical binding]; other site
767434003543	homodimer interface [polypeptide binding]; other site
767434003544	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
767434003545	L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140
767434003546	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
767434003547	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434003548	homodimer interface [polypeptide binding]; other site
767434003549	catalytic residue [active]
767434003550	cobyric acid synthase; Provisional; Region: PRK00784
767434003551	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
767434003552	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
767434003553	catalytic triad [active]
767434003554	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
767434003555	homotrimer interface [polypeptide binding]; other site
767434003556	Walker A motif; other site
767434003557	GTP binding site [chemical binding]; other site
767434003558	Walker B motif; other site
767434003559	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
767434003560	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
767434003561	putative dimer interface [polypeptide binding]; other site
767434003562	active site pocket [active]
767434003563	putative cataytic base [active]
767434003564	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
767434003565	catalytic core [active]
767434003566	cobalamin synthase; Reviewed; Region: cobS; PRK00235
767434003567	Subfamily of the nitroreductase family that includes BluB protein in Rhodobacter capsulatus is involved in the conversion of cobinamide to cobalamin in Cobalamin (vitamin B12) biosynthesis. Nitroreductases typically reduce their substrates by using NAD(P)...; Region: BluB; cd02145
767434003568	putative FMN binding site [chemical binding]; other site
767434003569	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
767434003570	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
767434003571	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
767434003572	catalytic triad [active]
767434003573	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
767434003574	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
767434003575	homodimer interface [polypeptide binding]; other site
767434003576	Walker A motif; other site
767434003577	ATP binding site [chemical binding]; other site
767434003578	hydroxycobalamin binding site [chemical binding]; other site
767434003579	Walker B motif; other site
767434003580	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
767434003581	short chain dehydrogenase; Provisional; Region: PRK09291
767434003582	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
767434003583	NADP binding site [chemical binding]; other site
767434003584	active site
767434003585	steroid binding site; other site
767434003586	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
767434003587	EamA-like transporter family; Region: EamA; pfam00892
767434003588	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
767434003589	Malic enzyme, N-terminal domain; Region: malic; pfam00390
767434003590	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
767434003591	putative NAD(P) binding site [chemical binding]; other site
767434003592	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434003593	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434003594	Secretin and TonB N terminus short domain; Region: STN; smart00965
767434003595	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434003596	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
767434003597	fec operon regulator FecR; Reviewed; Region: PRK09774
767434003598	FecR protein; Region: FecR; pfam04773
767434003599	RNA polymerase sigma factor FecI; Provisional; Region: PRK09651
767434003600	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
767434003601	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
767434003602	DNA binding residues [nucleotide binding]
767434003603	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
767434003604	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434003605	N-terminal plug; other site
767434003606	ligand-binding site [chemical binding]; other site
767434003607	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434003608	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434003609	short chain dehydrogenase; Provisional; Region: PRK06500
767434003610	classical (c) SDRs; Region: SDR_c; cd05233
767434003611	NAD(P) binding site [chemical binding]; other site
767434003612	active site
767434003613	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434003614	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
767434003615	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
767434003616	SmpB-tmRNA interface; other site
767434003617	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
767434003618	putative coenzyme Q binding site [chemical binding]; other site
767434003619	hypothetical protein; Validated; Region: PRK01777
767434003620	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
767434003621	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
767434003622	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
767434003623	metal binding site 2 [ion binding]; metal-binding site
767434003624	putative DNA binding helix; other site
767434003625	metal binding site 1 [ion binding]; metal-binding site
767434003626	dimer interface [polypeptide binding]; other site
767434003627	structural Zn2+ binding site [ion binding]; other site
767434003628	MASE1; Region: MASE1; cl17823
767434003629	Signal transduction histidine kinase, glucose-6-phosphate specific [Signal transduction mechanisms]; Region: UhpB; COG3851
767434003630	Histidine kinase; Region: HisKA_3; pfam07730
767434003631	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434003632	ATP binding site [chemical binding]; other site
767434003633	Mg2+ binding site [ion binding]; other site
767434003634	G-X-G motif; other site
767434003635	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
767434003636	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434003637	active site
767434003638	phosphorylation site [posttranslational modification]
767434003639	intermolecular recognition site; other site
767434003640	dimerization interface [polypeptide binding]; other site
767434003641	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
767434003642	DNA binding residues [nucleotide binding]
767434003643	dimerization interface [polypeptide binding]; other site
767434003644	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
767434003645	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
767434003646	Walker A/P-loop; other site
767434003647	ATP binding site [chemical binding]; other site
767434003648	Q-loop/lid; other site
767434003649	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
767434003650	ABC transporter signature motif; other site
767434003651	Walker B; other site
767434003652	D-loop; other site
767434003653	H-loop/switch region; other site
767434003654	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
767434003655	Transcriptional regulator; Region: Rrf2; cl17282
767434003656	GrpE; Region: GrpE; pfam01025
767434003657	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
767434003658	dimer interface [polypeptide binding]; other site
767434003659	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
767434003660	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
767434003661	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
767434003662	nucleotide binding site [chemical binding]; other site
767434003663	chaperone protein DnaJ; Provisional; Region: PRK10767
767434003664	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
767434003665	HSP70 interaction site [polypeptide binding]; other site
767434003666	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
767434003667	substrate binding site [polypeptide binding]; other site
767434003668	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
767434003669	Zn binding sites [ion binding]; other site
767434003670	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
767434003671	dimer interface [polypeptide binding]; other site
767434003672	dihydrodipicolinate reductase; Provisional; Region: PRK00048
767434003673	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
767434003674	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
767434003675	Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; Region: ECM27; COG0530
767434003676	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
767434003677	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
767434003678	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
767434003679	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
767434003680	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
767434003681	catalytic site [active]
767434003682	subunit interface [polypeptide binding]; other site
767434003683	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
767434003684	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
767434003685	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
767434003686	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
767434003687	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
767434003688	ATP-grasp domain; Region: ATP-grasp_4; cl17255
767434003689	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
767434003690	IMP binding site; other site
767434003691	dimer interface [polypeptide binding]; other site
767434003692	interdomain contacts; other site
767434003693	partial ornithine binding site; other site
767434003694	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
767434003695	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
767434003696	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
767434003697	Fimbrial protein; Region: Fimbrial; cl01416
767434003698	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
767434003699	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
767434003700	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
767434003701	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
767434003702	PapC N-terminal domain; Region: PapC_N; pfam13954
767434003703	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
767434003704	PapC C-terminal domain; Region: PapC_C; pfam13953
767434003705	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
767434003706	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
767434003707	methionine sulfoxide reductase A; Provisional; Region: PRK14054
767434003708	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
767434003709	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
767434003710	active site
767434003711	FMN binding site [chemical binding]; other site
767434003712	2,4-decadienoyl-CoA binding site; other site
767434003713	catalytic residue [active]
767434003714	4Fe-4S cluster binding site [ion binding]; other site
767434003715	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
767434003716	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
767434003717	cytidylate kinase; Provisional; Region: cmk; PRK00023
767434003718	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
767434003719	CMP-binding site; other site
767434003720	The sites determining sugar specificity; other site
767434003721	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
767434003722	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
767434003723	RNA binding site [nucleotide binding]; other site
767434003724	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
767434003725	RNA binding site [nucleotide binding]; other site
767434003726	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
767434003727	RNA binding site [nucleotide binding]; other site
767434003728	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
767434003729	RNA binding site [nucleotide binding]; other site
767434003730	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
767434003731	RNA binding site [nucleotide binding]; other site
767434003732	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
767434003733	RNA binding site [nucleotide binding]; other site
767434003734	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
767434003735	IHF dimer interface [polypeptide binding]; other site
767434003736	IHF - DNA interface [nucleotide binding]; other site
767434003737	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
767434003738	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
767434003739	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
767434003740	G1 box; other site
767434003741	GTP/Mg2+ binding site [chemical binding]; other site
767434003742	Switch I region; other site
767434003743	G2 box; other site
767434003744	G3 box; other site
767434003745	Switch II region; other site
767434003746	G4 box; other site
767434003747	G5 box; other site
767434003748	Nucleoside recognition; Region: Gate; pfam07670
767434003749	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
767434003750	Protein of unknown function (DUF4254); Region: DUF4254; pfam14063
767434003751	PAS fold; Region: PAS_4; pfam08448
767434003752	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
767434003753	putative active site [active]
767434003754	heme pocket [chemical binding]; other site
767434003755	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
767434003756	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434003757	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434003758	hydroxyproline-2-epimerase; Provisional; Region: PRK13970
767434003759	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
767434003760	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
767434003761	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
767434003762	inhibitor site; inhibition site
767434003763	active site
767434003764	dimer interface [polypeptide binding]; other site
767434003765	catalytic residue [active]
767434003766	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
767434003767	Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129
767434003768	dimer interface [polypeptide binding]; other site
767434003769	NADP binding site [chemical binding]; other site
767434003770	catalytic residues [active]
767434003771	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
767434003772	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
767434003773	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434003774	N-terminal plug; other site
767434003775	ligand-binding site [chemical binding]; other site
767434003776	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
767434003777	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
767434003778	alpha-galactosidase; Region: PLN02808; cl17638
767434003779	amino acid transporter; Region: 2A0306; TIGR00909
767434003780	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
767434003781	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4805
767434003782	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
767434003783	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
767434003784	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cl17196
767434003785	ATP binding site [chemical binding]; other site
767434003786	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
767434003787	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
767434003788	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
767434003789	Glycosyltransferase family 9 (heptosyltransferase); Region: Glyco_transf_9; pfam01075
767434003790	putative active site [active]
767434003791	Lipopolysaccharide kinase (Kdo/WaaP) family; Region: Kdo; cl17488
767434003792	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
767434003793	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
767434003794	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434003795	Walker A motif; other site
767434003796	ATP binding site [chemical binding]; other site
767434003797	Walker B motif; other site
767434003798	arginine finger; other site
767434003799	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
767434003800	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
767434003801	hypothetical protein; Validated; Region: PRK00153
767434003802	recombination protein RecR; Reviewed; Region: recR; PRK00076
767434003803	RecR protein; Region: RecR; pfam02132
767434003804	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
767434003805	putative active site [active]
767434003806	putative metal-binding site [ion binding]; other site
767434003807	tetramer interface [polypeptide binding]; other site
767434003808	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
767434003809	nucleotide binding site/active site [active]
767434003810	HIT family signature motif; other site
767434003811	catalytic residue [active]
767434003812	Outer membrane lipoprotein Slp family; Region: Slp; pfam03843
767434003813	Domain of unknown function (DUF3488); Region: DUF3488; pfam11992
767434003814	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
767434003815	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
767434003816	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
767434003817	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
767434003818	Protein of unknown function DUF58; Region: DUF58; pfam01882
767434003819	MoxR-like ATPases [General function prediction only]; Region: COG0714
767434003820	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434003821	Walker A motif; other site
767434003822	ATP binding site [chemical binding]; other site
767434003823	Walker B motif; other site
767434003824	arginine finger; other site
767434003825	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
767434003826	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
767434003827	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
767434003828	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
767434003829	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
767434003830	dimer interface [polypeptide binding]; other site
767434003831	active site
767434003832	CoA binding pocket [chemical binding]; other site
767434003833	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
767434003834	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
767434003835	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
767434003836	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
767434003837	NAD(P) binding site [chemical binding]; other site
767434003838	homotetramer interface [polypeptide binding]; other site
767434003839	homodimer interface [polypeptide binding]; other site
767434003840	active site
767434003841	acyl carrier protein; Provisional; Region: acpP; PRK00982
767434003842	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
767434003843	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
767434003844	dimer interface [polypeptide binding]; other site
767434003845	active site
767434003846	hypothetical protein; Validated; Region: PRK09070
767434003847	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
767434003848	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
767434003849	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
767434003850	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
767434003851	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434003852	catalytic residue [active]
767434003853	YceG-like family; Region: YceG; pfam02618
767434003854	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
767434003855	dimerization interface [polypeptide binding]; other site
767434003856	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
767434003857	thymidylate kinase; Validated; Region: tmk; PRK00698
767434003858	TMP-binding site; other site
767434003859	ATP-binding site [chemical binding]; other site
767434003860	DNA polymerase III subunit delta'; Validated; Region: PRK08769
767434003861	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
767434003862	PilZ domain; Region: PilZ; cl01260
767434003863	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
767434003864	NADH dehydrogenase subunit B; Validated; Region: PRK06411
767434003865	NADH dehydrogenase subunit C; Provisional; Region: PRK06074
767434003866	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
767434003867	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
767434003868	NADH dehydrogenase subunit D; Validated; Region: PRK06075
767434003869	NADH dehydrogenase subunit E; Validated; Region: PRK07539
767434003870	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
767434003871	putative dimer interface [polypeptide binding]; other site
767434003872	[2Fe-2S] cluster binding site [ion binding]; other site
767434003873	NADH-quinone oxidoreductase, F subunit; Region: nuoF_fam; TIGR01959
767434003874	SLBB domain; Region: SLBB; pfam10531
767434003875	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
767434003876	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
767434003877	NADH dehydrogenase subunit G; Validated; Region: PRK09129
767434003878	catalytic loop [active]
767434003879	iron binding site [ion binding]; other site
767434003880	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
767434003881	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
767434003882	molybdopterin cofactor binding site; other site
767434003883	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
767434003884	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
767434003885	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
767434003886	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
767434003887	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
767434003888	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
767434003889	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
767434003890	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
767434003891	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
767434003892	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
767434003893	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
767434003894	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
767434003895	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
767434003896	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
767434003897	Domain of unknown function (DUF955); Region: DUF955; pfam06114
767434003898	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
767434003899	Part of AAA domain; Region: AAA_19; pfam13245
767434003900	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
767434003901	Family description; Region: UvrD_C_2; pfam13538
767434003902	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
767434003903	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
767434003904	active site
767434003905	catalytic site [active]
767434003906	substrate binding site [chemical binding]; other site
767434003907	putative phosphoketolase; Provisional; Region: PRK05261
767434003908	XFP N-terminal domain; Region: XFP_N; pfam09364
767434003909	XFP C-terminal domain; Region: XFP_C; pfam09363
767434003910	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
767434003911	propionate/acetate kinase; Provisional; Region: PRK12379
767434003912	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
767434003913	NADH(P)-binding; Region: NAD_binding_10; pfam13460
767434003914	NAD binding site [chemical binding]; other site
767434003915	substrate binding site [chemical binding]; other site
767434003916	putative active site [active]
767434003917	Predicted transcriptional regulators [Transcription]; Region: COG1733
767434003918	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
767434003919	dimerization interface [polypeptide binding]; other site
767434003920	putative DNA binding site [nucleotide binding]; other site
767434003921	putative Zn2+ binding site [ion binding]; other site
767434003922	Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178
767434003923	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434003924	Walker A/P-loop; other site
767434003925	ATP binding site [chemical binding]; other site
767434003926	Q-loop/lid; other site
767434003927	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434003928	ABC transporter signature motif; other site
767434003929	Walker B; other site
767434003930	D-loop; other site
767434003931	H-loop/switch region; other site
767434003932	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434003933	Walker A/P-loop; other site
767434003934	ATP binding site [chemical binding]; other site
767434003935	Q-loop/lid; other site
767434003936	ABC transporter signature motif; other site
767434003937	Walker B; other site
767434003938	D-loop; other site
767434003939	H-loop/switch region; other site
767434003940	AAA ATPase domain; Region: AAA_16; pfam13191
767434003941	Uncharacterized conserved protein (DUF2075); Region: DUF2075; pfam09848
767434003942	Uncharacterized conserved protein [Function unknown]; Region: COG3410
767434003943	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434003944	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
767434003945	putative substrate translocation pore; other site
767434003946	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434003947	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434003948	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
767434003949	putative effector binding pocket; other site
767434003950	putative dimerization interface [polypeptide binding]; other site
767434003951	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
767434003952	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
767434003953	active site
767434003954	catalytic tetrad [active]
767434003955	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
767434003956	Zn2+ binding site [ion binding]; other site
767434003957	Mg2+ binding site [ion binding]; other site
767434003958	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
767434003959	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
767434003960	cofactor binding site; other site
767434003961	DNA binding site [nucleotide binding]
767434003962	substrate interaction site [chemical binding]; other site
767434003963	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
767434003964	YqaJ-like viral recombinase domain; Region: YqaJ; cl09232
767434003965	RecT family; Region: RecT; cl04285
767434003966	hypothetical protein; Provisional; Region: PRK09946
767434003967	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u5; cd11542
767434003968	metal binding site [ion binding]; metal-binding site
767434003969	tRNA_anti-like; Region: tRNA_anti-like; pfam12869
767434003970	Short C-terminal domain; Region: SHOCT; pfam09851
767434003971	Helix-turn-helix domain; Region: HTH_36; pfam13730
767434003972	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
767434003973	FMN-binding domain; Region: FMN_bind; cl01081
767434003974	Head fiber protein; Region: Phage_head_fibr; pfam11133
767434003975	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
767434003976	Terminase-like family; Region: Terminase_6; pfam03237
767434003977	Phage-related terminase [General function prediction only]; Region: COG5362; cl02216
767434003978	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
767434003979	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
767434003980	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4834
767434003981	Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950
767434003982	Protein of unknown function (DUF4054); Region: DUF4054; pfam13262
767434003983	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
767434003984	Protein of unknown function (DUF3277); Region: DUF3277; pfam11681
767434003985	virion protein; Provisional; Region: V; PHA02564
767434003986	Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; cl15410
767434003987	Baseplate J-like protein; Region: Baseplate_J; cl01294
767434003988	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
767434003989	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
767434003990	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
767434003991	active site
767434003992	DNA binding site [nucleotide binding]
767434003993	Int/Topo IB signature motif; other site
767434003994	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
767434003995	ThiC-associated domain; Region: ThiC-associated; pfam13667
767434003996	ThiC family; Region: ThiC; pfam01964
767434003997	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
767434003998	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
767434003999	thiS-thiF/thiG interaction site; other site
767434004000	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
767434004001	ThiS interaction site; other site
767434004002	putative active site [active]
767434004003	tetramer interface [polypeptide binding]; other site
767434004004	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
767434004005	active site
767434004006	thiamine phosphate binding site [chemical binding]; other site
767434004007	pyrophosphate binding site [ion binding]; other site
767434004008	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
767434004009	dimer interface [polypeptide binding]; other site
767434004010	substrate binding site [chemical binding]; other site
767434004011	ATP binding site [chemical binding]; other site
767434004012	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
767434004013	Protein of unknown function (DUF3574); Region: DUF3574; pfam12098
767434004014	Archaeal/vacuolar-type H+-ATPase subunit I [Energy production and conversion]; Region: NtpI; COG1269
767434004015	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
767434004016	dimer interface [polypeptide binding]; other site
767434004017	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
767434004018	active site
767434004019	metal binding site [ion binding]; metal-binding site
767434004020	glutathione binding site [chemical binding]; other site
767434004021	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
767434004022	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
767434004023	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
767434004024	MOSC domain; Region: MOSC; pfam03473
767434004025	ATP-dependent helicase HepA; Validated; Region: PRK04914
767434004026	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
767434004027	ATP binding site [chemical binding]; other site
767434004028	putative Mg++ binding site [ion binding]; other site
767434004029	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
767434004030	nucleotide binding region [chemical binding]; other site
767434004031	ATP-binding site [chemical binding]; other site
767434004032	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain [Signal transduction mechanisms / Transcription]; Region: COG4567
767434004033	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434004034	active site
767434004035	phosphorylation site [posttranslational modification]
767434004036	intermolecular recognition site; other site
767434004037	dimerization interface [polypeptide binding]; other site
767434004038	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
767434004039	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
767434004040	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434004041	phosphorylation site [posttranslational modification]
767434004042	dimer interface [polypeptide binding]; other site
767434004043	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434004044	ATP binding site [chemical binding]; other site
767434004045	G-X-G motif; other site
767434004046	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
767434004047	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434004048	putative substrate translocation pore; other site
767434004049	POT family; Region: PTR2; cl17359
767434004050	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
767434004051	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
767434004052	tetramer interface [polypeptide binding]; other site
767434004053	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434004054	catalytic residue [active]
767434004055	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
767434004056	LemA family; Region: LemA; pfam04011
767434004057	Repair protein; Region: Repair_PSII; pfam04536
767434004058	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
767434004059	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
767434004060	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
767434004061	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
767434004062	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
767434004063	Outer membrane efflux protein; Region: OEP; pfam02321
767434004064	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
767434004065	HlyD family secretion protein; Region: HlyD_3; pfam13437
767434004066	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
767434004067	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
767434004068	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
767434004069	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
767434004070	Secretory lipase; Region: LIP; pfam03583
767434004071	thymidylate synthase; Reviewed; Region: thyA; PRK01827
767434004072	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
767434004073	dimerization interface [polypeptide binding]; other site
767434004074	active site
767434004075	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
767434004076	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
767434004077	folate binding site [chemical binding]; other site
767434004078	NADP+ binding site [chemical binding]; other site
767434004079	citrate-proton symporter; Provisional; Region: PRK15075
767434004080	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434004081	putative substrate translocation pore; other site
767434004082	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
767434004083	[2Fe-2S] cluster binding site [ion binding]; other site
767434004084	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
767434004085	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434004086	dimer interface [polypeptide binding]; other site
767434004087	phosphorylation site [posttranslational modification]
767434004088	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434004089	ATP binding site [chemical binding]; other site
767434004090	Mg2+ binding site [ion binding]; other site
767434004091	G-X-G motif; other site
767434004092	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
767434004093	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434004094	active site
767434004095	phosphorylation site [posttranslational modification]
767434004096	intermolecular recognition site; other site
767434004097	dimerization interface [polypeptide binding]; other site
767434004098	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
767434004099	DNA binding site [nucleotide binding]
767434004100	HIT domain; Region: HIT; pfam01230
767434004101	nucleotide binding site/active site [active]
767434004102	HIT family signature motif; other site
767434004103	catalytic residue [active]
767434004104	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
767434004105	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
767434004106	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
767434004107	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
767434004108	FeS/SAM binding site; other site
767434004109	Protein of unknown function (DUF3025); Region: DUF3025; pfam11227
767434004110	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
767434004111	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
767434004112	catalytic residues [active]
767434004113	Paraquat-inducible protein A; Region: PqiA; pfam04403
767434004114	Paraquat-inducible protein A; Region: PqiA; pfam04403
767434004115	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
767434004116	mce related protein; Region: MCE; pfam02470
767434004117	mce related protein; Region: MCE; pfam02470
767434004118	mce related protein; Region: MCE; pfam02470
767434004119	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
767434004120	Protein of unknown function (DUF330); Region: DUF330; pfam03886
767434004121	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
767434004122	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
767434004123	HIGH motif; other site
767434004124	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
767434004125	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
767434004126	active site
767434004127	KMSKS motif; other site
767434004128	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
767434004129	tRNA binding surface [nucleotide binding]; other site
767434004130	Lipopolysaccharide-assembly; Region: LptE; cl01125
767434004131	DNA polymerase III, delta subunit; Region: holA; TIGR01128
767434004132	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
767434004133	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
767434004134	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
767434004135	active site
767434004136	(T/H)XGH motif; other site
767434004137	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
767434004138	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
767434004139	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
767434004140	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
767434004141	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
767434004142	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
767434004143	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434004144	Walker A/P-loop; other site
767434004145	ATP binding site [chemical binding]; other site
767434004146	Q-loop/lid; other site
767434004147	ABC transporter signature motif; other site
767434004148	Walker B; other site
767434004149	D-loop; other site
767434004150	H-loop/switch region; other site
767434004151	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
767434004152	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
767434004153	Walker A/P-loop; other site
767434004154	ATP binding site [chemical binding]; other site
767434004155	Q-loop/lid; other site
767434004156	ABC transporter signature motif; other site
767434004157	Walker B; other site
767434004158	D-loop; other site
767434004159	H-loop/switch region; other site
767434004160	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
767434004161	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
767434004162	putative hydrolase; Provisional; Region: PRK11460
767434004163	Predicted esterase [General function prediction only]; Region: COG0400
767434004164	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
767434004165	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
767434004166	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
767434004167	Maf-like protein; Region: Maf; pfam02545
767434004168	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
767434004169	active site
767434004170	dimer interface [polypeptide binding]; other site
767434004171	CAAX protease self-immunity; Region: Abi; pfam02517
767434004172	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
767434004173	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
767434004174	Transporter associated domain; Region: CorC_HlyC; smart01091
767434004175	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
767434004176	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
767434004177	Ligand binding site; other site
767434004178	Putative Catalytic site; other site
767434004179	DXD motif; other site
767434004180	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
767434004181	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
767434004182	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
767434004183	active site
767434004184	RfbF is a putative dTDP-rhamnosyl transferase; Region: GT2_RfbF_like; cd02526
767434004185	Ligand binding site; other site
767434004186	L-rhamnosyltransferase; Region: rhamnosyltran; TIGR01556
767434004187	Uncharacterized protein conserved in bacteria (DUF2236); Region: DUF2236; pfam09995
767434004188	molybdopterin biosynthesis protein MoeB; Validated; Region: PRK08762
767434004189	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
767434004190	active site residue [active]
767434004191	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
767434004192	ATP binding site [chemical binding]; other site
767434004193	substrate interface [chemical binding]; other site
767434004194	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
767434004195	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
767434004196	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
767434004197	homodimer interface [polypeptide binding]; other site
767434004198	NADP binding site [chemical binding]; other site
767434004199	substrate binding site [chemical binding]; other site
767434004200	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
767434004201	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
767434004202	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
767434004203	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
767434004204	active site
767434004205	GMP synthase; Reviewed; Region: guaA; PRK00074
767434004206	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
767434004207	AMP/PPi binding site [chemical binding]; other site
767434004208	candidate oxyanion hole; other site
767434004209	catalytic triad [active]
767434004210	potential glutamine specificity residues [chemical binding]; other site
767434004211	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
767434004212	ATP Binding subdomain [chemical binding]; other site
767434004213	Ligand Binding sites [chemical binding]; other site
767434004214	Dimerization subdomain; other site
767434004215	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
767434004216	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
767434004217	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
767434004218	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
767434004219	putative transposase OrfB; Reviewed; Region: PHA02517
767434004220	Integrase core domain; Region: rve; pfam00665
767434004221	Integrase core domain; Region: rve_3; pfam13683
767434004222	Protein of unknown function (DUF1153); Region: DUF1153; pfam06627
767434004223	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
767434004224	Integrase core domain; Region: rve; pfam00665
767434004225	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
767434004226	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
767434004227	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
767434004228	catalytic residue [active]
767434004229	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4320
767434004230	Uncharacterized protein conserved in bacteria (DUF2252); Region: DUF2252; pfam10009
767434004231	Bacterial protein of unknown function (DUF925); Region: DUF925; pfam06042
767434004232	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434004233	NAD(P) binding site [chemical binding]; other site
767434004234	active site
767434004235	Inosine-uridine preferring nucleoside hydrolase; Region: IU_nuc_hydro; pfam01156
767434004236	active site
767434004237	Precorrin-6A synthase, the cobalamin biosynthesis enzyme CobF; Region: Precorrin-6A-synthase; cd11643
767434004238	active site
767434004239	SAM binding site [chemical binding]; other site
767434004240	homodimer interface [polypeptide binding]; other site
767434004241	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434004242	TPR motif; other site
767434004243	binding surface
767434004244	Tetratricopeptide repeat; Region: TPR_12; pfam13424
767434004245	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434004246	binding surface
767434004247	TPR motif; other site
767434004248	Tetratricopeptide repeat; Region: TPR_12; pfam13424
767434004249	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434004250	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434004251	metal binding site [ion binding]; metal-binding site
767434004252	active site
767434004253	I-site; other site
767434004254	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
767434004255	Part of AAA domain; Region: AAA_19; pfam13245
767434004256	Phage endonuclease I; Region: Phage_endo_I; cl11622
767434004257	Family description; Region: UvrD_C_2; pfam13538
767434004258	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
767434004259	FOG: WD40 repeat [General function prediction only]; Region: COG2319
767434004260	PAS domain; Region: PAS_9; pfam13426
767434004261	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
767434004262	putative active site [active]
767434004263	heme pocket [chemical binding]; other site
767434004264	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
767434004265	PAS domain; Region: PAS_9; pfam13426
767434004266	putative active site [active]
767434004267	heme pocket [chemical binding]; other site
767434004268	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
767434004269	dimer interface [polypeptide binding]; other site
767434004270	putative CheW interface [polypeptide binding]; other site
767434004271	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
767434004272	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
767434004273	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434004274	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434004275	AefR-like transcriptional repressor, C-terminal region; Region: TetR_C_7; pfam14246
767434004276	EamA-like transporter family; Region: EamA; pfam00892
767434004277	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
767434004278	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434004279	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434004280	N-terminal plug; other site
767434004281	ligand-binding site [chemical binding]; other site
767434004282	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
767434004283	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434004284	N-terminal plug; other site
767434004285	ligand-binding site [chemical binding]; other site
767434004286	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434004287	Walker A/P-loop; other site
767434004288	ATP binding site [chemical binding]; other site
767434004289	Q-loop/lid; other site
767434004290	ABC transporter signature motif; other site
767434004291	Walker B; other site
767434004292	D-loop; other site
767434004293	H-loop/switch region; other site
767434004294	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
767434004295	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
767434004296	ligand binding site [chemical binding]; other site
767434004297	homodimer interface [polypeptide binding]; other site
767434004298	NAD(P) binding site [chemical binding]; other site
767434004299	trimer interface B [polypeptide binding]; other site
767434004300	trimer interface A [polypeptide binding]; other site
767434004301	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
767434004302	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
767434004303	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
767434004304	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
767434004305	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
767434004306	NAD(P) binding site [chemical binding]; other site
767434004307	catalytic residues [active]
767434004308	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
767434004309	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
767434004310	NAD binding site [chemical binding]; other site
767434004311	substrate binding site [chemical binding]; other site
767434004312	catalytic Zn binding site [ion binding]; other site
767434004313	tetramer interface [polypeptide binding]; other site
767434004314	structural Zn binding site [ion binding]; other site
767434004315	Purine nucleoside permease (NUP); Region: NUP; cl17832
767434004316	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
767434004317	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
767434004318	active site
767434004319	tetramer interface [polypeptide binding]; other site
767434004320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434004321	D-galactonate transporter; Region: 2A0114; TIGR00893
767434004322	putative substrate translocation pore; other site
767434004323	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
767434004324	Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129
767434004325	dimer interface [polypeptide binding]; other site
767434004326	NADP binding site [chemical binding]; other site
767434004327	catalytic residues [active]
767434004328	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
767434004329	5-dehydro-4-deoxyglucarate dehydratase, also called 5-keto-4-deoxy-glucarate dehydratase (KDGDH); Region: KDGDH; cd00951
767434004330	putative active site [active]
767434004331	catalytic residue [active]
767434004332	Major royal jelly protein; Region: MRJP; pfam03022
767434004333	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
767434004334	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434004335	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to regulators involved in the catabolism of aromatic compounds, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like_1; cd08447
767434004336	putative dimerization interface [polypeptide binding]; other site
767434004337	putative substrate binding pocket [chemical binding]; other site
767434004338	glutathione reductase; Validated; Region: PRK06116
767434004339	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
767434004340	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
767434004341	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
767434004342	PepSY-associated TM helix; Region: PepSY_TM_3; pfam13706
767434004343	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
767434004344	polyhydroxyalkanoate synthesis repressor PhaR; Region: PHA_reg_PhaR; TIGR01848
767434004345	PHB/PHA accumulation regulator DNA-binding domain; Region: PHB_acc_N; pfam07879
767434004346	PHB accumulation regulatory domain; Region: PHB_acc; pfam05233
767434004347	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
767434004348	active site
767434004349	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
767434004350	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
767434004351	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
767434004352	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
767434004353	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
767434004354	Iron-sulfur protein interface; other site
767434004355	proximal quinone binding site [chemical binding]; other site
767434004356	SdhD (CybS) interface [polypeptide binding]; other site
767434004357	proximal heme binding site [chemical binding]; other site
767434004358	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit-like; composed of predominantly uncharacterized bacterial proteins with similarity to the E. coli SdhD subunit. One characterized protein is the respiratory...; Region: SQR_TypeC_SdhD_like; cd03495
767434004359	putative SdhC subunit interface [polypeptide binding]; other site
767434004360	putative proximal heme binding site [chemical binding]; other site
767434004361	putative Iron-sulfur protein interface [polypeptide binding]; other site
767434004362	putative proximal quinone binding site; other site
767434004363	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK09078
767434004364	L-aspartate oxidase; Provisional; Region: PRK06175
767434004365	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
767434004366	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
767434004367	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
767434004368	Flavinator of succinate dehydrogenase; Region: Sdh5; cl01110
767434004369	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
767434004370	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
767434004371	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
767434004372	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
767434004373	Walker A/P-loop; other site
767434004374	ATP binding site [chemical binding]; other site
767434004375	Q-loop/lid; other site
767434004376	ABC transporter signature motif; other site
767434004377	Walker B; other site
767434004378	D-loop; other site
767434004379	H-loop/switch region; other site
767434004380	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
767434004381	Competence protein; Region: Competence; pfam03772
767434004382	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
767434004383	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
767434004384	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
767434004385	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
767434004386	lipid A export permease/ATP-binding protein MsbA; Region: MsbA_lipidA; TIGR02203
767434004387	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
767434004388	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
767434004389	Walker A/P-loop; other site
767434004390	ATP binding site [chemical binding]; other site
767434004391	Q-loop/lid; other site
767434004392	ABC transporter signature motif; other site
767434004393	Walker B; other site
767434004394	D-loop; other site
767434004395	H-loop/switch region; other site
767434004396	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
767434004397	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
767434004398	AMIN domain; Region: AMIN; pfam11741
767434004399	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
767434004400	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
767434004401	active site
767434004402	metal binding site [ion binding]; metal-binding site
767434004403	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
767434004404	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
767434004405	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
767434004406	Zn binding site [ion binding]; other site
767434004407	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
767434004408	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
767434004409	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
767434004410	ATP binding site [chemical binding]; other site
767434004411	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
767434004412	Protein of unknown function (DUF1684); Region: DUF1684; pfam07920
767434004413	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
767434004414	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
767434004415	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
767434004416	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
767434004417	putative active site [active]
767434004418	putative CoA binding site [chemical binding]; other site
767434004419	nudix motif; other site
767434004420	metal binding site [ion binding]; metal-binding site
767434004421	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
767434004422	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
767434004423	active site residue [active]
767434004424	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
767434004425	active site residue [active]
767434004426	Uncharacterized conserved protein [Function unknown]; Region: COG5316
767434004427	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
767434004428	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
767434004429	active site
767434004430	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
767434004431	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
767434004432	active site
767434004433	catalytic tetrad [active]
767434004434	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
767434004435	RibD C-terminal domain; Region: RibD_C; cl17279
767434004436	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
767434004437	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
767434004438	formaldehyde dehydrogenase (FDH)-like; Region: FDH_like_ADH3; cd08287
767434004439	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
767434004440	catalytic Zn binding site [ion binding]; other site
767434004441	NAD(P) binding site [chemical binding]; other site
767434004442	structural Zn binding site [ion binding]; other site
767434004443	Yhdh and yhfp-like putative quinone oxidoreductases; Region: MDR_yhdh_yhfp; cd05280
767434004444	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
767434004445	NADP binding site [chemical binding]; other site
767434004446	dimer interface [polypeptide binding]; other site
767434004447	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
767434004448	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
767434004449	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
767434004450	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
767434004451	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
767434004452	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
767434004453	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
767434004454	E3 interaction surface; other site
767434004455	lipoyl attachment site [posttranslational modification]; other site
767434004456	e3 binding domain; Region: E3_binding; pfam02817
767434004457	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
767434004458	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
767434004459	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
767434004460	TPP-binding site [chemical binding]; other site
767434004461	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
767434004462	Cupin superfamily protein; Region: Cupin_4; pfam08007
767434004463	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
767434004464	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
767434004465	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434004466	N-terminal plug; other site
767434004467	ligand-binding site [chemical binding]; other site
767434004468	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
767434004469	adenylosuccinate lyase; Provisional; Region: PRK09285
767434004470	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
767434004471	tetramer interface [polypeptide binding]; other site
767434004472	active site
767434004473	fumarate hydratase; Reviewed; Region: fumC; PRK00485
767434004474	Class II fumarases; Region: Fumarase_classII; cd01362
767434004475	active site
767434004476	tetramer interface [polypeptide binding]; other site
767434004477	cytosine deaminase; Validated; Region: PRK07572
767434004478	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
767434004479	active site
767434004480	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
767434004481	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
767434004482	Response regulator receiver domain; Region: Response_reg; pfam00072
767434004483	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434004484	active site
767434004485	phosphorylation site [posttranslational modification]
767434004486	intermolecular recognition site; other site
767434004487	dimerization interface [polypeptide binding]; other site
767434004488	Hpt domain; Region: Hpt; pfam01627
767434004489	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
767434004490	TRAM domain; Region: TRAM; pfam01938
767434004491	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434004492	S-adenosylmethionine binding site [chemical binding]; other site
767434004493	CYTH-like Clostridium thermocellum TTM-like subgroup 1; Region: CYTH-like_CthTTM-like_1; cd07891
767434004494	putative active site [active]
767434004495	putative metal binding residues [ion binding]; other site
767434004496	signature motif; other site
767434004497	putative dimer interface [polypeptide binding]; other site
767434004498	putative phosphate binding site [ion binding]; other site
767434004499	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
767434004500	beta-hexosaminidase; Provisional; Region: PRK05337
767434004501	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
767434004502	active site
767434004503	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
767434004504	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
767434004505	DNA-binding site [nucleotide binding]; DNA binding site
767434004506	RNA-binding motif; other site
767434004507	ABC transporter, permease/ATP-binding protein; Region: MsbA_rel; TIGR02204
767434004508	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
767434004509	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434004510	Walker A/P-loop; other site
767434004511	ATP binding site [chemical binding]; other site
767434004512	Q-loop/lid; other site
767434004513	ABC transporter signature motif; other site
767434004514	Walker B; other site
767434004515	D-loop; other site
767434004516	H-loop/switch region; other site
767434004517	copper-resistance protein, CopA family; Region: copper_res_A; TIGR01480
767434004518	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
767434004519	Multicopper oxidase; Region: Cu-oxidase; pfam00394
767434004520	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
767434004521	Copper resistance protein B precursor (CopB); Region: CopB; pfam05275
767434004522	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
767434004523	DNA binding residues [nucleotide binding]
767434004524	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
767434004525	dimer interface [polypeptide binding]; other site
767434004526	metal binding site [ion binding]; metal-binding site
767434004527	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
767434004528	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
767434004529	metal-binding site [ion binding]
767434004530	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
767434004531	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
767434004532	metal-binding site [ion binding]
767434004533	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
767434004534	Soluble P-type ATPase [General function prediction only]; Region: COG4087
767434004535	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
767434004536	metal-binding site [ion binding]
767434004537	asparagine synthetase B; Provisional; Region: asnB; PRK09431
767434004538	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
767434004539	active site
767434004540	dimer interface [polypeptide binding]; other site
767434004541	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
767434004542	Ligand Binding Site [chemical binding]; other site
767434004543	Molecular Tunnel; other site
767434004544	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
767434004545	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
767434004546	dimer interface [polypeptide binding]; other site
767434004547	catalytic residues [active]
767434004548	peptide chain release factor 2; Validated; Region: prfB; PRK00578
767434004549	This domain is found in peptide chain release factors; Region: PCRF; smart00937
767434004550	RF-1 domain; Region: RF-1; pfam00472
767434004551	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
767434004552	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
767434004553	dimer interface [polypeptide binding]; other site
767434004554	putative anticodon binding site; other site
767434004555	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
767434004556	motif 1; other site
767434004557	active site
767434004558	motif 2; other site
767434004559	motif 3; other site
767434004560	GWT1; Region: GWT1; cl02109
767434004561	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
767434004562	EamA-like transporter family; Region: EamA; pfam00892
767434004563	Major royal jelly protein; Region: MRJP; pfam03022
767434004564	YciI-like protein; Reviewed; Region: PRK11370
767434004565	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
767434004566	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
767434004567	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
767434004568	Walker A/P-loop; other site
767434004569	ATP binding site [chemical binding]; other site
767434004570	Q-loop/lid; other site
767434004571	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; pfam06470
767434004572	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
767434004573	ABC transporter signature motif; other site
767434004574	Walker B; other site
767434004575	D-loop; other site
767434004576	H-loop/switch region; other site
767434004577	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
767434004578	FtsZ protein binding site [polypeptide binding]; other site
767434004579	polyphosphate kinase; Provisional; Region: PRK05443
767434004580	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
767434004581	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
767434004582	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
767434004583	putative active site [active]
767434004584	catalytic site [active]
767434004585	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
767434004586	putative domain interface [polypeptide binding]; other site
767434004587	putative active site [active]
767434004588	catalytic site [active]
767434004589	Uncharacterized conserved protein [Function unknown]; Region: COG1434
767434004590	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
767434004591	putative active site [active]
767434004592	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
767434004593	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
767434004594	generic binding surface II; other site
767434004595	generic binding surface I; other site
767434004596	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
767434004597	PLD-like domain; Region: PLDc_2; pfam13091
767434004598	putative active site [active]
767434004599	catalytic site [active]
767434004600	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
767434004601	PLD-like domain; Region: PLDc_2; pfam13091
767434004602	putative active site [active]
767434004603	catalytic site [active]
767434004604	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434004605	Major Facilitator Superfamily; Region: MFS_1; pfam07690
767434004606	putative substrate translocation pore; other site
767434004607	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434004608	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
767434004609	Haem-binding domain; Region: Haem_bd; pfam14376
767434004610	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
767434004611	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
767434004612	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
767434004613	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
767434004614	putative substrate binding pocket [chemical binding]; other site
767434004615	trimer interface [polypeptide binding]; other site
767434004616	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
767434004617	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
767434004618	putative active site [active]
767434004619	putative metal binding site [ion binding]; other site
767434004620	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
767434004621	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
767434004622	NAD binding site [chemical binding]; other site
767434004623	catalytic residues [active]
767434004624	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; Region: HpaG-C-term; TIGR02303
767434004625	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
767434004626	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
767434004627	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
767434004628	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
767434004629	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
767434004630	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434004631	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434004632	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434004633	metal binding site [ion binding]; metal-binding site
767434004634	active site
767434004635	I-site; other site
767434004636	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
767434004637	heme-binding site [chemical binding]; other site
767434004638	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434004639	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434004640	metal binding site [ion binding]; metal-binding site
767434004641	active site
767434004642	I-site; other site
767434004643	Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: HisS; COG0124
767434004644	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
767434004645	dimer interface [polypeptide binding]; other site
767434004646	motif 1; other site
767434004647	active site
767434004648	motif 2; other site
767434004649	motif 3; other site
767434004650	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
767434004651	anticodon binding site; other site
767434004652	Trp repressor protein; Region: Trp_repressor; cl17266
767434004653	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
767434004654	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
767434004655	HisG, C-terminal domain; Region: HisG_C; cl06867
767434004656	histidinol dehydrogenase; Region: hisD; TIGR00069
767434004657	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
767434004658	dimerization interface [polypeptide binding]; other site
767434004659	NAD binding site [chemical binding]; other site
767434004660	product binding site; other site
767434004661	substrate binding site [chemical binding]; other site
767434004662	zinc binding site [ion binding]; other site
767434004663	catalytic residues [active]
767434004664	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
767434004665	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
767434004666	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434004667	homodimer interface [polypeptide binding]; other site
767434004668	catalytic residue [active]
767434004669	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
767434004670	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
767434004671	active site
767434004672	motif I; other site
767434004673	motif II; other site
767434004674	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
767434004675	putative active site pocket [active]
767434004676	4-fold oligomerization interface [polypeptide binding]; other site
767434004677	metal binding residues [ion binding]; metal-binding site
767434004678	3-fold/trimer interface [polypeptide binding]; other site
767434004679	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
767434004680	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
767434004681	putative active site [active]
767434004682	oxyanion strand; other site
767434004683	catalytic triad [active]
767434004684	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
767434004685	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
767434004686	catalytic residues [active]
767434004687	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
767434004688	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
767434004689	substrate binding site [chemical binding]; other site
767434004690	glutamase interaction surface [polypeptide binding]; other site
767434004691	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
767434004692	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
767434004693	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
767434004694	metal binding site [ion binding]; metal-binding site
767434004695	Phosphopantetheinyl transferase component of siderophore synthetase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntD; COG2977
767434004696	Peptidase C13 family; Region: Peptidase_C13; cl02159
767434004697	Predicted enolase-phosphatase [Energy production and conversion]; Region: COG4229
767434004698	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
767434004699	motif II; other site
767434004700	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
767434004701	Cupin domain; Region: Cupin_2; cl17218
767434004702	methylthioribulose-1-phosphate dehydratase; Provisional; Region: PRK09220
767434004703	intersubunit interface [polypeptide binding]; other site
767434004704	active site
767434004705	Zn2+ binding site [ion binding]; other site
767434004706	High potential iron-sulfur protein; Region: HIPIP; pfam01355
767434004707	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
767434004708	SelR domain; Region: SelR; pfam01641
767434004709	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
767434004710	FeS/SAM binding site; other site
767434004711	elongation factor P; Validated; Region: PRK00529
767434004712	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
767434004713	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
767434004714	RNA binding site [nucleotide binding]; other site
767434004715	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
767434004716	RNA binding site [nucleotide binding]; other site
767434004717	N-ethylammeline chlorohydrolase; Provisional; Region: PRK09045
767434004718	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
767434004719	active site
767434004720	putative substrate binding pocket [chemical binding]; other site
767434004721	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
767434004722	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434004723	S-adenosylmethionine binding site [chemical binding]; other site
767434004724	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
767434004725	motif II; other site
767434004726	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
767434004727	putative GTP cyclohydrolase; Provisional; Region: PRK13674
767434004728	Uncharacterized conserved protein [Function unknown]; Region: COG1359
767434004729	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
767434004730	Coenzyme A binding pocket [chemical binding]; other site
767434004731	Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4232
767434004732	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
767434004733	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
767434004734	DsbD alpha interface [polypeptide binding]; other site
767434004735	catalytic residues [active]
767434004736	RNA polymerase sigma factor; Reviewed; Region: PRK12527
767434004737	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
767434004738	DNA binding residues [nucleotide binding]
767434004739	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
767434004740	FecR protein; Region: FecR; pfam04773
767434004741	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434004742	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434004743	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434004744	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
767434004745	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
767434004746	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
767434004747	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
767434004748	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
767434004749	PhnA protein; Region: PhnA; pfam03831
767434004750	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
767434004751	Putative ammonia monooxygenase; Region: AmoA; pfam05145
767434004752	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
767434004753	Isochorismatase family; Region: Isochorismatase; pfam00857
767434004754	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
767434004755	catalytic triad [active]
767434004756	conserved cis-peptide bond; other site
767434004757	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434004758	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434004759	Cysteine dioxygenase type I; Region: CDO_I; pfam05995
767434004760	glucokinase, proteobacterial type; Region: glk; TIGR00749
767434004761	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
767434004762	nucleotide binding site [chemical binding]; other site
767434004763	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
767434004764	active site
767434004765	dimer interface [polypeptide binding]; other site
767434004766	catalytic nucleophile [active]
767434004767	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
767434004768	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
767434004769	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
767434004770	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
767434004771	active site
767434004772	catalytic tetrad [active]
767434004773	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434004774	metabolite-proton symporter; Region: 2A0106; TIGR00883
767434004775	putative substrate translocation pore; other site
767434004776	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
767434004777	Transcriptional regulator [Transcription]; Region: IclR; COG1414
767434004778	Bacterial transcriptional regulator; Region: IclR; pfam01614
767434004779	type VI secretion-associated protein, ImpA family; Region: VI_chp_8; TIGR03363
767434004780	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
767434004781	Protein of unknown function (DUF770); Region: DUF770; pfam05591
767434004782	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
767434004783	Protein of unknown function (DUF877); Region: DUF877; pfam05943
767434004784	Protein of unknown function (DUF796); Region: DUF796; pfam05638
767434004785	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
767434004786	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
767434004787	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
767434004788	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
767434004789	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
767434004790	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
767434004791	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
767434004792	Uncharacterized protein conserved in bacteria (DUF2169); Region: DUF2169; pfam09937
767434004793	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
767434004794	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
767434004795	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
767434004796	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
767434004797	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
767434004798	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
767434004799	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
767434004800	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
767434004801	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
767434004802	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
767434004803	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
767434004804	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
767434004805	Protein of unknown function (DUF3540); Region: DUF3540; pfam12059
767434004806	Domain of unknown function (DUF4150); Region: DUF4150; pfam13665
767434004807	Type VI secretion lipoprotein; Region: T6SS-SciN; cl01405
767434004808	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
767434004809	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
767434004810	hypothetical protein; Provisional; Region: PRK07033
767434004811	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
767434004812	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
767434004813	ligand binding site [chemical binding]; other site
767434004814	type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348
767434004815	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
767434004816	G1 box; other site
767434004817	GTP/Mg2+ binding site [chemical binding]; other site
767434004818	G2 box; other site
767434004819	Switch I region; other site
767434004820	G3 box; other site
767434004821	Switch II region; other site
767434004822	G4 box; other site
767434004823	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
767434004824	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
767434004825	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cl00062
767434004826	phosphopeptide binding site; other site
767434004827	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
767434004828	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
767434004829	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
767434004830	Protein of unknown function (DUF1523); Region: DUF1523; pfam07509
767434004831	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
767434004832	N-acetyl-D-glucosamine binding site [chemical binding]; other site
767434004833	catalytic residue [active]
767434004834	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
767434004835	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
767434004836	HemK family putative methylases; Region: hemK_fam; TIGR00536
767434004837	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434004838	S-adenosylmethionine binding site [chemical binding]; other site
767434004839	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
767434004840	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
767434004841	Tetramer interface [polypeptide binding]; other site
767434004842	active site
767434004843	FMN-binding site [chemical binding]; other site
767434004844	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
767434004845	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
767434004846	FeS/SAM binding site; other site
767434004847	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
767434004848	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
767434004849	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
767434004850	GTP binding site; other site
767434004851	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
767434004852	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
767434004853	dimer interface [polypeptide binding]; other site
767434004854	putative functional site; other site
767434004855	putative MPT binding site; other site
767434004856	putative oxidoreductase; Provisional; Region: PRK09939
767434004857	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
767434004858	putative molybdopterin cofactor binding site [chemical binding]; other site
767434004859	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
767434004860	putative molybdopterin cofactor binding site; other site
767434004861	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
767434004862	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
767434004863	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
767434004864	putative ligand binding residues [chemical binding]; other site
767434004865	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
767434004866	dimer interface [polypeptide binding]; other site
767434004867	putative PBP binding regions; other site
767434004868	ABC-ATPase subunit  interface; other site
767434004869	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
767434004870	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
767434004871	Walker A/P-loop; other site
767434004872	ATP binding site [chemical binding]; other site
767434004873	Q-loop/lid; other site
767434004874	ABC transporter signature motif; other site
767434004875	Walker B; other site
767434004876	D-loop; other site
767434004877	H-loop/switch region; other site
767434004878	Cupin domain; Region: Cupin_2; pfam07883
767434004879	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
767434004880	short chain dehydrogenase; Provisional; Region: PRK07062
767434004881	putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR; Region: BKR_like_SDR_like; cd05344
767434004882	putative NAD(P) binding site [chemical binding]; other site
767434004883	putative active site [active]
767434004884	hypothetical protein; Provisional; Region: PRK07064
767434004885	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
767434004886	PYR/PP interface [polypeptide binding]; other site
767434004887	dimer interface [polypeptide binding]; other site
767434004888	TPP binding site [chemical binding]; other site
767434004889	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
767434004890	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cd00568
767434004891	TPP-binding site [chemical binding]; other site
767434004892	L-aspartate dehydrogenase; Provisional; Region: PRK13303
767434004893	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
767434004894	Domain of unknown function DUF108; Region: DUF108; pfam01958
767434004895	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
767434004896	Uncharacterized Candidatus pelagibacter aldehyde dehydrogenase, DhaS-like; Region: ALDH_DhaS; cd07114
767434004897	NAD(P) binding site [chemical binding]; other site
767434004898	catalytic residues [active]
767434004899	C-terminal domain of Burkholderia sp. NF100 MhqB and similar proteins; MhqB is a type I extradiol dioxygenase involved in the catabolism of methylhydroquinone, an intermediate in the degradation of fenitrothion; Region: MhqB_like_C; cd08360
767434004900	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
767434004901	putative active site [active]
767434004902	putative metal binding site [ion binding]; other site
767434004903	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434004904	putative substrate translocation pore; other site
767434004905	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
767434004906	dimer interface [polypeptide binding]; other site
767434004907	FMN binding site [chemical binding]; other site
767434004908	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
767434004909	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
767434004910	Coniferyl aldehyde dehydrogenase-like; Region: ALDH_CALDH_CalB; cd07133
767434004911	NAD(P) binding site [chemical binding]; other site
767434004912	catalytic residues [active]
767434004913	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
767434004914	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
767434004915	active site
767434004916	catalytic tetrad [active]
767434004917	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
767434004918	active site
767434004919	DNA binding site [nucleotide binding]
767434004920	Int/Topo IB signature motif; other site
767434004921	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
767434004922	catalytic motif [active]
767434004923	Catalytic residue [active]
767434004924	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
767434004925	Transposase; Region: HTH_Tnp_1; pfam01527
767434004926	Peptidase M14-like domain; uncharacterized subfamily; Region: M14-like_4; cd06231
767434004927	putative active site [active]
767434004928	Zn binding site [ion binding]; other site
767434004929	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
767434004930	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434004931	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434004932	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
767434004933	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
767434004934	dimer interface [polypeptide binding]; other site
767434004935	active site
767434004936	metal binding site [ion binding]; metal-binding site
767434004937	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
767434004938	Prostaglandin dehydrogenases; Region: PGDH; cd05288
767434004939	NAD(P) binding site [chemical binding]; other site
767434004940	substrate binding site [chemical binding]; other site
767434004941	dimer interface [polypeptide binding]; other site
767434004942	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
767434004943	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
767434004944	potential catalytic triad [active]
767434004945	conserved cys residue [active]
767434004946	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434004947	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434004948	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
767434004949	putative effector binding pocket; other site
767434004950	dimerization interface [polypeptide binding]; other site
767434004951	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
767434004952	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434004953	putative substrate translocation pore; other site
767434004954	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
767434004955	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
767434004956	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434004957	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434004958	metal binding site [ion binding]; metal-binding site
767434004959	active site
767434004960	I-site; other site
767434004961	Inhibitor of vertebrate lysozyme (Ivy); Region: Ivy; cl07428
767434004962	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
767434004963	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
767434004964	ATP-grasp domain; Region: ATP-grasp_4; cl17255
767434004965	YaeQ protein; Region: YaeQ; pfam07152
767434004966	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
767434004967	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
767434004968	homodimer interface [polypeptide binding]; other site
767434004969	substrate-cofactor binding pocket; other site
767434004970	catalytic residue [active]
767434004971	Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318
767434004972	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
767434004973	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
767434004974	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
767434004975	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434004976	Cytochrome c; Region: Cytochrom_C; pfam00034
767434004977	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
767434004978	Transcriptional regulators [Transcription]; Region: PurR; COG1609
767434004979	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
767434004980	DNA binding site [nucleotide binding]
767434004981	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
767434004982	dimerization interface [polypeptide binding]; other site
767434004983	ligand binding site [chemical binding]; other site
767434004984	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
767434004985	FtsH Extracellular; Region: FtsH_ext; pfam06480
767434004986	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
767434004987	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434004988	Walker A motif; other site
767434004989	ATP binding site [chemical binding]; other site
767434004990	Walker B motif; other site
767434004991	arginine finger; other site
767434004992	Peptidase family M41; Region: Peptidase_M41; pfam01434
767434004993	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
767434004994	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434004995	S-adenosylmethionine binding site [chemical binding]; other site
767434004996	CRS1 / YhbY (CRM) domain; Region: CRS1_YhbY; pfam01985
767434004997	Mth938-like domain. The members of this family include: Mth938, 2P1, Xcr35, Rpa2829, and several uncharacterized sequences. Mth938 is a hypothetical protein encoded by the Methanobacterium thermoautotrophicum (Mth) genome. This protein crystallizes as a...; Region: Mth938-like; cl00182
767434004998	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
767434004999	Peptidase family M23; Region: Peptidase_M23; pfam01551
767434005000	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
767434005001	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
767434005002	Methyltransferase domain; Region: Methyltransf_18; pfam12847
767434005003	S-adenosylmethionine binding site [chemical binding]; other site
767434005004	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
767434005005	Smr domain; Region: Smr; pfam01713
767434005006	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
767434005007	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
767434005008	Permutation of conserved domain; other site
767434005009	active site
767434005010	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
767434005011	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
767434005012	MgtE intracellular N domain; Region: MgtE_N; smart00924
767434005013	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
767434005014	Divalent cation transporter; Region: MgtE; cl00786
767434005015	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
767434005016	homotrimer interaction site [polypeptide binding]; other site
767434005017	zinc binding site [ion binding]; other site
767434005018	CDP-binding sites; other site
767434005019	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
767434005020	substrate binding site; other site
767434005021	dimer interface; other site
767434005022	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
767434005023	Septum formation initiator; Region: DivIC; cl17659
767434005024	enolase; Provisional; Region: eno; PRK00077
767434005025	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
767434005026	dimer interface [polypeptide binding]; other site
767434005027	metal binding site [ion binding]; metal-binding site
767434005028	substrate binding pocket [chemical binding]; other site
767434005029	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
767434005030	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
767434005031	CTP synthetase; Validated; Region: pyrG; PRK05380
767434005032	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
767434005033	Catalytic site [active]
767434005034	active site
767434005035	UTP binding site [chemical binding]; other site
767434005036	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
767434005037	active site
767434005038	putative oxyanion hole; other site
767434005039	catalytic triad [active]
767434005040	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
767434005041	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
767434005042	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
767434005043	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
767434005044	active site
767434005045	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
767434005046	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434005047	Mg2+ binding site [ion binding]; other site
767434005048	G-X-G motif; other site
767434005049	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
767434005050	anchoring element; other site
767434005051	dimer interface [polypeptide binding]; other site
767434005052	ATP binding site [chemical binding]; other site
767434005053	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
767434005054	active site
767434005055	metal binding site [ion binding]; metal-binding site
767434005056	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
767434005057	ATP-NAD kinase; Region: NAD_kinase; pfam01513
767434005058	inorganic polyphosphate/ATP-NAD kinase; Reviewed; Region: ppnK; PRK04761
767434005059	Bacterial NAD-glutamate dehydrogenase; Region: Bac_GDH; pfam05088
767434005060	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; smart00839
767434005061	periplasmic multidrug efflux lipoprotein precursor; Reviewed; Region: PRK09578
767434005062	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
767434005063	HlyD family secretion protein; Region: HlyD_3; pfam13437
767434005064	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
767434005065	Protein export membrane protein; Region: SecD_SecF; cl14618
767434005066	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
767434005067	dimerization interface [polypeptide binding]; other site
767434005068	putative DNA binding site [nucleotide binding]; other site
767434005069	putative Zn2+ binding site [ion binding]; other site
767434005070	Methyltransferase domain; Region: Methyltransf_23; pfam13489
767434005071	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434005072	S-adenosylmethionine binding site [chemical binding]; other site
767434005073	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
767434005074	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
767434005075	Methionine synthase I, cobalamin-binding domain [Amino acid transport and metabolism]; Region: MetH; COG1410
767434005076	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
767434005077	substrate binding pocket [chemical binding]; other site
767434005078	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
767434005079	B12 binding site [chemical binding]; other site
767434005080	cobalt ligand [ion binding]; other site
767434005081	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
767434005082	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
767434005083	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
767434005084	amidase catalytic site [active]
767434005085	Zn binding residues [ion binding]; other site
767434005086	substrate binding site [chemical binding]; other site
767434005087	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
767434005088	Lipid A Biosynthesis N-terminal domain; Region: LAB_N; cl01627
767434005089	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
767434005090	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
767434005091	active site pocket [active]
767434005092	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434005093	D-galactonate transporter; Region: 2A0114; TIGR00893
767434005094	putative substrate translocation pore; other site
767434005095	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
767434005096	dimethyl sulfone monooxygenase SfnG; Region: LLM_DMSO2_sfnG; TIGR04021
767434005097	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
767434005098	active site
767434005099	dimer interface [polypeptide binding]; other site
767434005100	non-prolyl cis peptide bond; other site
767434005101	insertion regions; other site
767434005102	replicative DNA helicase; Region: DnaB; TIGR00665
767434005103	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
767434005104	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
767434005105	Walker A motif; other site
767434005106	ATP binding site [chemical binding]; other site
767434005107	Walker B motif; other site
767434005108	DNA binding loops [nucleotide binding]
767434005109	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
767434005110	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
767434005111	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
767434005112	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
767434005113	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
767434005114	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
767434005115	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
767434005116	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
767434005117	putative dimer interface [polypeptide binding]; other site
767434005118	putative anticodon binding site; other site
767434005119	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
767434005120	homodimer interface [polypeptide binding]; other site
767434005121	motif 1; other site
767434005122	motif 2; other site
767434005123	active site
767434005124	motif 3; other site
767434005125	Maltose operon periplasmic protein precursor (MalM); Region: MalM; cl11647
767434005126	short chain dehydrogenase; Provisional; Region: PRK08339
767434005127	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434005128	NAD(P) binding site [chemical binding]; other site
767434005129	active site
767434005130	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434005131	putative substrate translocation pore; other site
767434005132	Protein of unknown function (DUF3465); Region: DUF3465; pfam11948
767434005133	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
767434005134	homotrimer interaction site [polypeptide binding]; other site
767434005135	putative active site [active]
767434005136	Predicted membrane protein [Function unknown]; Region: COG4648
767434005137	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
767434005138	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
767434005139	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
767434005140	Ubiquitin-like proteins; Region: UBQ; cl00155
767434005141	charged pocket; other site
767434005142	hydrophobic patch; other site
767434005143	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
767434005144	MoaE homodimer interface [polypeptide binding]; other site
767434005145	MoaD interaction [polypeptide binding]; other site
767434005146	active site residues [active]
767434005147	bifunctional molybdenum cofactor biosynthesis protein MoaC/MogA; Provisional; Region: moaC; PRK03604
767434005148	MoaC family. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine derivative to the precursor...; Region: MoaC; cd00528
767434005149	trimer interface [polypeptide binding]; other site
767434005150	dimer interface [polypeptide binding]; other site
767434005151	putative active site [active]
767434005152	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
767434005153	MPT binding site; other site
767434005154	trimer interface [polypeptide binding]; other site
767434005155	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
767434005156	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
767434005157	XdhC Rossmann domain; Region: XdhC_C; pfam13478
767434005158	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
767434005159	Ligand binding site; other site
767434005160	metal-binding site
767434005161	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
767434005162	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
767434005163	dimer interface [polypeptide binding]; other site
767434005164	putative functional site; other site
767434005165	putative MPT binding site; other site
767434005166	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434005167	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434005168	Cytochrome c; Region: Cytochrom_C; pfam00034
767434005169	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
767434005170	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
767434005171	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
767434005172	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
767434005173	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
767434005174	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
767434005175	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
767434005176	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434005177	error-prone DNA polymerase; Validated; Region: dnaE2; PRK05672
767434005178	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at DnaE2 gene; Region: PHP_PolIIIA_DnaE2; cd07434
767434005179	putative active site [active]
767434005180	putative PHP Thumb interface [polypeptide binding]; other site
767434005181	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
767434005182	generic binding surface I; other site
767434005183	generic binding surface II; other site
767434005184	DNA Polymerase Y-family; Region: PolY_like; cd03468
767434005185	active site
767434005186	DNA binding site [nucleotide binding]
767434005187	Uncharacterized conserved protein [Function unknown]; Region: COG4544
767434005188	LexA repressor; Validated; Region: PRK00215
767434005189	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
767434005190	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
767434005191	Catalytic site [active]
767434005192	malate dehydrogenase; Provisional; Region: PRK13529
767434005193	Malic enzyme, N-terminal domain; Region: malic; pfam00390
767434005194	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
767434005195	NAD(P) binding site [chemical binding]; other site
767434005196	Membrane transport protein; Region: Mem_trans; cl09117
767434005197	TPR repeat; Region: TPR_11; pfam13414
767434005198	Uncharacterized protein conserved in bacteria (DUF2076); Region: DUF2076; pfam09849
767434005199	AAA domain; Region: AAA_30; pfam13604
767434005200	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
767434005201	Walker A motif; other site
767434005202	ATP binding site [chemical binding]; other site
767434005203	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
767434005204	AAA domain; Region: AAA_12; pfam13087
767434005205	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
767434005206	putative active site [active]
767434005207	catalytic site [active]
767434005208	Peptidase family M48; Region: Peptidase_M48; cl12018
767434005209	putative GTP cyclohydrolase; Provisional; Region: PRK13674
767434005210	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
767434005211	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
767434005212	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
767434005213	Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]; Region: Fur; COG0735
767434005214	metal binding site 2 [ion binding]; metal-binding site
767434005215	putative DNA binding helix; other site
767434005216	metal binding site 1 [ion binding]; metal-binding site
767434005217	dimer interface [polypeptide binding]; other site
767434005218	structural Zn2+ binding site [ion binding]; other site
767434005219	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434005220	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434005221	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
767434005222	putative effector binding pocket; other site
767434005223	dimerization interface [polypeptide binding]; other site
767434005224	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
767434005225	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434005226	putative substrate translocation pore; other site
767434005227	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
767434005228	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
767434005229	active site
767434005230	catalytic tetrad [active]
767434005231	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
767434005232	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
767434005233	FMN binding site [chemical binding]; other site
767434005234	active site
767434005235	substrate binding site [chemical binding]; other site
767434005236	catalytic residue [active]
767434005237	Rhodococcus ruber 6-oxolauric acid dehydrogenase-like; Region: ALDH_CddD_SSP0762; cd07138
767434005238	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
767434005239	NAD binding site [chemical binding]; other site
767434005240	catalytic residues [active]
767434005241	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434005242	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434005243	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
767434005244	putative effector binding pocket; other site
767434005245	putative dimerization interface [polypeptide binding]; other site
767434005246	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
767434005247	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
767434005248	FAD binding pocket [chemical binding]; other site
767434005249	FAD binding motif [chemical binding]; other site
767434005250	phosphate binding motif [ion binding]; other site
767434005251	NAD binding pocket [chemical binding]; other site
767434005252	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
767434005253	Helix-turn-helix domain; Region: HTH_18; pfam12833
767434005254	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434005255	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434005256	D-lactate dehydrogenase; Provisional; Region: PRK11183
767434005257	FAD binding domain; Region: FAD_binding_4; pfam01565
767434005258	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
767434005259	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434005260	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434005261	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
767434005262	putative dimerization interface [polypeptide binding]; other site
767434005263	putative substrate binding pocket [chemical binding]; other site
767434005264	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
767434005265	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434005266	NAD(P) binding site [chemical binding]; other site
767434005267	active site
767434005268	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
767434005269	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
767434005270	Protein of unknown function (DUF1153); Region: DUF1153; pfam06627
767434005271	putative transposase OrfB; Reviewed; Region: PHA02517
767434005272	Integrase core domain; Region: rve; pfam00665
767434005273	Integrase core domain; Region: rve_3; pfam13683
767434005274	Protein of unknown function (DUF1376); Region: DUF1376; pfam07120
767434005275	Predicted transcriptional regulator [Transcription]; Region: COG2932
767434005276	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
767434005277	non-specific DNA binding site [nucleotide binding]; other site
767434005278	salt bridge; other site
767434005279	sequence-specific DNA binding site [nucleotide binding]; other site
767434005280	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
767434005281	Catalytic site [active]
767434005282	chaperone protein DnaJ; Provisional; Region: PRK14295
767434005283	RecT family; Region: RecT; cl04285
767434005284	YqaJ-like viral recombinase domain; Region: YqaJ; cl09232
767434005285	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
767434005286	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
767434005287	active site
767434005288	DNA binding site [nucleotide binding]
767434005289	Int/Topo IB signature motif; other site
767434005290	Domain of unknown function (DUF927); Region: DUF927; pfam06048
767434005291	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
767434005292	active site
767434005293	metal binding site [ion binding]; metal-binding site
767434005294	interdomain interaction site; other site
767434005295	KilA-N domain; Region: KilA-N; pfam04383
767434005296	Helix-turn-helix domain; Region: HTH_39; pfam14090
767434005297	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
767434005298	integrase; Provisional; Region: PRK09692
767434005299	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
767434005300	active site
767434005301	Int/Topo IB signature motif; other site
767434005302	preprotein translocase subunit SecG; Reviewed; Region: secG; PRK06870
767434005303	triosephosphate isomerase; Provisional; Region: PRK14567
767434005304	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
767434005305	substrate binding site [chemical binding]; other site
767434005306	dimer interface [polypeptide binding]; other site
767434005307	catalytic triad [active]
767434005308	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
767434005309	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
767434005310	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
767434005311	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
767434005312	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
767434005313	active site
767434005314	substrate binding site [chemical binding]; other site
767434005315	metal binding site [ion binding]; metal-binding site
767434005316	dihydropteroate synthase; Region: DHPS; TIGR01496
767434005317	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
767434005318	substrate binding pocket [chemical binding]; other site
767434005319	dimer interface [polypeptide binding]; other site
767434005320	inhibitor binding site; inhibition site
767434005321	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
767434005322	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
767434005323	catalytic site [active]
767434005324	putative active site [active]
767434005325	putative substrate binding site [chemical binding]; other site
767434005326	dimer interface [polypeptide binding]; other site
767434005327	exonuclease I; Provisional; Region: sbcB; PRK11779
767434005328	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
767434005329	active site
767434005330	catalytic site [active]
767434005331	substrate binding site [chemical binding]; other site
767434005332	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
767434005333	Conserved hypothetical protein (DUF2461); Region: DUF2461; pfam09365
767434005334	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434005335	metabolite-proton symporter; Region: 2A0106; TIGR00883
767434005336	putative substrate translocation pore; other site
767434005337	Protein of unknown function (DUF1302); Region: DUF1302; pfam06980
767434005338	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
767434005339	EF-P lysine aminoacylase GenX; Region: genX; TIGR00462
767434005340	motif 1; other site
767434005341	dimer interface [polypeptide binding]; other site
767434005342	active site
767434005343	motif 2; other site
767434005344	motif 3; other site
767434005345	Ligase N family; Region: LIGANc; smart00532
767434005346	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
767434005347	nucleotide binding pocket [chemical binding]; other site
767434005348	K-X-D-G motif; other site
767434005349	catalytic site [active]
767434005350	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
767434005351	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
767434005352	Helix-hairpin-helix motif; Region: HHH_2; pfam12826
767434005353	Major Facilitator Superfamily; Region: MFS_1; pfam07690
767434005354	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434005355	putative substrate translocation pore; other site
767434005356	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434005357	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
767434005358	nucleoside/Zn binding site; other site
767434005359	dimer interface [polypeptide binding]; other site
767434005360	catalytic motif [active]
767434005361	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a...; Region: Nudix_Hydrolase_1; cd03674
767434005362	nudix motif; other site
767434005363	amino acid transporter; Region: 2A0306; TIGR00909
767434005364	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
767434005365	amino acid transporter; Region: 2A0306; TIGR00909
767434005366	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
767434005367	GTP-binding protein Der; Reviewed; Region: PRK00093
767434005368	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
767434005369	G1 box; other site
767434005370	GTP/Mg2+ binding site [chemical binding]; other site
767434005371	Switch I region; other site
767434005372	G2 box; other site
767434005373	Switch II region; other site
767434005374	G3 box; other site
767434005375	G4 box; other site
767434005376	G5 box; other site
767434005377	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
767434005378	G1 box; other site
767434005379	GTP/Mg2+ binding site [chemical binding]; other site
767434005380	Switch I region; other site
767434005381	G2 box; other site
767434005382	G3 box; other site
767434005383	Switch II region; other site
767434005384	G4 box; other site
767434005385	G5 box; other site
767434005386	outer membrane assembly lipoprotein YfgL; Region: assembly_YfgL; TIGR03300
767434005387	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
767434005388	Trp docking motif [polypeptide binding]; other site
767434005389	active site
767434005390	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
767434005391	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
767434005392	Helix-turn-helix domain; Region: HTH_25; pfam13413
767434005393	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
767434005394	type IV pilus biogenesis/stability protein PilW; Region: type_IV_pilW; TIGR02521
767434005395	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434005396	binding surface
767434005397	TPR motif; other site
767434005398	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434005399	binding surface
767434005400	TPR motif; other site
767434005401	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
767434005402	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
767434005403	FeS/SAM binding site; other site
767434005404	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
767434005405	active site
767434005406	multimer interface [polypeptide binding]; other site
767434005407	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434005408	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434005409	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
767434005410	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
767434005411	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
767434005412	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
767434005413	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
767434005414	substrate binding site [chemical binding]; other site
767434005415	oxyanion hole (OAH) forming residues; other site
767434005416	trimer interface [polypeptide binding]; other site
767434005417	acetyl-CoA acetyltransferase; Provisional; Region: PRK09052
767434005418	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
767434005419	dimer interface [polypeptide binding]; other site
767434005420	active site
767434005421	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
767434005422	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
767434005423	putative acyl-acceptor binding pocket; other site
767434005424	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
767434005425	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
767434005426	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
767434005427	catalytic residue [active]
767434005428	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
767434005429	FeS assembly protein SufD; Region: sufD; TIGR01981
767434005430	FeS assembly ATPase SufC; Region: sufC; TIGR01978
767434005431	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
767434005432	Walker A/P-loop; other site
767434005433	ATP binding site [chemical binding]; other site
767434005434	Q-loop/lid; other site
767434005435	ABC transporter signature motif; other site
767434005436	Walker B; other site
767434005437	D-loop; other site
767434005438	H-loop/switch region; other site
767434005439	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
767434005440	putative ABC transporter; Region: ycf24; CHL00085
767434005441	FeS assembly SUF system regulator, gammaproteobacterial; Region: suf_reg_Xantho; TIGR02944
767434005442	Transcriptional regulator; Region: Rrf2; pfam02082
767434005443	Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347
767434005444	Nitrogen regulatory protein P-II; Region: P-II; smart00938
767434005445	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
767434005446	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
767434005447	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
767434005448	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
767434005449	Phosphotransferase enzyme family; Region: APH; pfam01636
767434005450	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
767434005451	substrate binding site [chemical binding]; other site
767434005452	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
767434005453	NTP_transferase_like_1 is a member of the nucleotidyl transferase family; Region: NTP_transferase_like_1; cd06422
767434005454	Substrate binding site; other site
767434005455	metal-binding site
767434005456	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
767434005457	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
767434005458	active site
767434005459	tetramer interface; other site
767434005460	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
767434005461	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
767434005462	NAD(P) binding site [chemical binding]; other site
767434005463	homodimer interface [polypeptide binding]; other site
767434005464	substrate binding site [chemical binding]; other site
767434005465	active site
767434005466	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
767434005467	Glycosyltransferase 4 (GT4) includes both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases. They catalyze the transfer of a D-N-acetylhexosamine 1-phosphate to a membrane-bound...; Region: GT_MraY-like; cl10571
767434005468	Mg++ binding site [ion binding]; other site
767434005469	putative catalytic motif [active]
767434005470	tetratricopeptide repeat protein; Provisional; Region: PRK11788
767434005471	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434005472	binding surface
767434005473	TPR motif; other site
767434005474	elongation factor P; Provisional; Region: PRK04542
767434005475	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
767434005476	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
767434005477	RNA binding site [nucleotide binding]; other site
767434005478	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
767434005479	RNA binding site [nucleotide binding]; other site
767434005480	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
767434005481	kynureninase; Region: kynureninase; TIGR01814
767434005482	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
767434005483	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
767434005484	catalytic residue [active]
767434005485	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
767434005486	anti sigma factor interaction site; other site
767434005487	regulatory phosphorylation site [posttranslational modification]; other site
767434005488	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
767434005489	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
767434005490	dimer interface [polypeptide binding]; other site
767434005491	putative CheW interface [polypeptide binding]; other site
767434005492	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
767434005493	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434005494	active site
767434005495	phosphorylation site [posttranslational modification]
767434005496	intermolecular recognition site; other site
767434005497	dimerization interface [polypeptide binding]; other site
767434005498	CheB methylesterase; Region: CheB_methylest; pfam01339
767434005499	CheD chemotactic sensory transduction; Region: CheD; cl00810
767434005500	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
767434005501	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
767434005502	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
767434005503	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
767434005504	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
767434005505	dimerization interface [polypeptide binding]; other site
767434005506	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
767434005507	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
767434005508	dimer interface [polypeptide binding]; other site
767434005509	putative CheW interface [polypeptide binding]; other site
767434005510	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
767434005511	putative CheA interaction surface; other site
767434005512	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
767434005513	putative binding surface; other site
767434005514	active site
767434005515	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
767434005516	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
767434005517	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434005518	ATP binding site [chemical binding]; other site
767434005519	Mg2+ binding site [ion binding]; other site
767434005520	G-X-G motif; other site
767434005521	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
767434005522	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
767434005523	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434005524	active site
767434005525	phosphorylation site [posttranslational modification]
767434005526	intermolecular recognition site; other site
767434005527	dimerization interface [polypeptide binding]; other site
767434005528	STAS domain; Region: STAS_2; pfam13466
767434005529	FlgN protein; Region: FlgN; pfam05130
767434005530	Anti-sigma-28 factor, FlgM; Region: FlgM; pfam04316
767434005531	SAF-like; Region: SAF_2; pfam13144
767434005532	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
767434005533	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
767434005534	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
767434005535	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
767434005536	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
767434005537	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434005538	active site
767434005539	phosphorylation site [posttranslational modification]
767434005540	intermolecular recognition site; other site
767434005541	dimerization interface [polypeptide binding]; other site
767434005542	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
767434005543	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
767434005544	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
767434005545	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
767434005546	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
767434005547	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
767434005548	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
767434005549	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
767434005550	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
767434005551	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
767434005552	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
767434005553	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640
767434005554	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
767434005555	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
767434005556	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
767434005557	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
767434005558	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
767434005559	Flagellar L-ring protein; Region: FlgH; pfam02107
767434005560	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
767434005561	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
767434005562	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
767434005563	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
767434005564	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
767434005565	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK06945
767434005566	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08870
767434005567	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
767434005568	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
767434005569	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
767434005570	catalytic residue [active]
767434005571	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
767434005572	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
767434005573	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
767434005574	Probable Catalytic site; other site
767434005575	metal-binding site
767434005576	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
767434005577	flagellin; Reviewed; Region: PRK08869
767434005578	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
767434005579	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
767434005580	flagellar capping protein; Reviewed; Region: fliD; PRK08032
767434005581	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
767434005582	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
767434005583	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
767434005584	Flagellar protein FliS; Region: FliS; cl00654
767434005585	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
767434005586	Flagellar regulatory protein FleQ; Region: FleQ; pfam06490
767434005587	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434005588	Walker A motif; other site
767434005589	ATP binding site [chemical binding]; other site
767434005590	Walker B motif; other site
767434005591	arginine finger; other site
767434005592	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
767434005593	Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139
767434005594	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
767434005595	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
767434005596	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
767434005597	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
767434005598	FliG C-terminal domain; Region: FliG_C; pfam01706
767434005599	Flagellar assembly protein FliH; Region: FliH; pfam02108
767434005600	flagellar protein export ATPase FliI; Region: FliI_clade1; TIGR03496
767434005601	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
767434005602	Walker A motif/ATP binding site; other site
767434005603	Walker B motif; other site
767434005604	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
767434005605	Flagellar basal body-associated protein FliL; Region: FliL; pfam03748
767434005606	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
767434005607	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
767434005608	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
767434005609	Flagellar biosynthesis protein, FliO; Region: FliO; pfam04347
767434005610	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
767434005611	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
767434005612	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
767434005613	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
767434005614	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
767434005615	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
767434005616	FHIPEP family; Region: FHIPEP; pfam00771
767434005617	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
767434005618	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
767434005619	AAA domain; Region: AAA_31; pfam13614
767434005620	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
767434005621	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
767434005622	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
767434005623	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
767434005624	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
767434005625	DNA binding residues [nucleotide binding]
767434005626	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
767434005627	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434005628	active site
767434005629	phosphorylation site [posttranslational modification]
767434005630	intermolecular recognition site; other site
767434005631	dimerization interface [polypeptide binding]; other site
767434005632	Chemotaxis phosphatase, CheZ; Region: CheZ; cl01219
767434005633	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
767434005634	putative binding surface; other site
767434005635	active site
767434005636	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
767434005637	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
767434005638	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434005639	ATP binding site [chemical binding]; other site
767434005640	Mg2+ binding site [ion binding]; other site
767434005641	G-X-G motif; other site
767434005642	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
767434005643	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
767434005644	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
767434005645	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
767434005646	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
767434005647	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
767434005648	ligand binding site [chemical binding]; other site
767434005649	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
767434005650	Protein of unknown function (DUF2802); Region: DUF2802; pfam10975
767434005651	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
767434005652	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
767434005653	putative catalytic cysteine [active]
767434005654	gamma-glutamyl kinase; Provisional; Region: PRK05429
767434005655	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
767434005656	nucleotide binding site [chemical binding]; other site
767434005657	homotetrameric interface [polypeptide binding]; other site
767434005658	putative phosphate binding site [ion binding]; other site
767434005659	putative allosteric binding site; other site
767434005660	PUA domain; Region: PUA; pfam01472
767434005661	argininosuccinate lyase; Provisional; Region: PRK00855
767434005662	Lyase class I_like superfamily: contains the lyase class I family, histidine ammonia-lyase and phenylalanine ammonia-lyase, which catalyze similar beta-elimination reactions; Region: Lyase_I_like; cl00013
767434005663	tetramer interface [polypeptide binding]; other site
767434005664	Purine nucleoside permease (NUP); Region: NUP; pfam06516
767434005665	N-acetyl-gamma-glutamyl-phosphate reductase, common form; Region: argC; TIGR01850
767434005666	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
767434005667	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
767434005668	acetylglutamate kinase; Provisional; Region: PRK04531
767434005669	AAK_NAGK-fArgBP: N-Acetyl-L-glutamate kinase (NAGK) of the fungal arginine-biosynthetic pathway (fArgBP). The nuclear-encoded, mitochondrial polyprotein precursor with an N-terminal NAGK (ArgB) domain (this CD), a central DUF619 domain, and a C-terminal...; Region: AAK_NAGK-fArgBP; cd04252
767434005670	putative nucleotide binding site [chemical binding]; other site
767434005671	putative N-acetyl-L-glutamate binding site [chemical binding]; other site
767434005672	DUF619 domain of various N-acetylglutamate Synthases (NAGS) of the urea (U) cycle of humans and fish; Region: DUF619-NAGS-U; cd04265
767434005673	acetylornithine deacetylase; Provisional; Region: PRK08737
767434005674	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
767434005675	metal binding site [ion binding]; metal-binding site
767434005676	argininosuccinate synthase; Provisional; Region: PRK13820
767434005677	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
767434005678	ANP binding site [chemical binding]; other site
767434005679	Substrate Binding Site II [chemical binding]; other site
767434005680	Substrate Binding Site I [chemical binding]; other site
767434005681	OsmC-like protein; Region: OsmC; cl00767
767434005682	Putative FMN-binding domain; Region: FMN_bind_2; pfam04299
767434005683	N-acetylornithine carbamoyltransferase; Reviewed; Region: PRK04523
767434005684	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
767434005685	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
767434005686	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
767434005687	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
767434005688	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
767434005689	active site
767434005690	HIGH motif; other site
767434005691	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
767434005692	KMSKS motif; other site
767434005693	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
767434005694	tRNA binding surface [nucleotide binding]; other site
767434005695	anticodon binding site; other site
767434005696	Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]; Region: sufE; COG2166
767434005697	DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism]; Region: NUC1; COG1864
767434005698	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
767434005699	active site
767434005700	substrate binding site [chemical binding]; other site
767434005701	Mg2+ binding site [ion binding]; other site
767434005702	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
767434005703	Protein of unknown function (DUF1470); Region: DUF1470; pfam07336
767434005704	CGNR zinc finger; Region: zf-CGNR; pfam11706
767434005705	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
767434005706	DNA repair protein RadA; Provisional; Region: PRK11823
767434005707	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
767434005708	Walker A motif; other site
767434005709	ATP binding site [chemical binding]; other site
767434005710	Walker B motif; other site
767434005711	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
767434005712	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
767434005713	dimerization interface [polypeptide binding]; other site
767434005714	putative DNA binding site [nucleotide binding]; other site
767434005715	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
767434005716	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
767434005717	active site
767434005718	FMN binding site [chemical binding]; other site
767434005719	substrate binding site [chemical binding]; other site
767434005720	homotetramer interface [polypeptide binding]; other site
767434005721	catalytic residue [active]
767434005722	Cupin domain; Region: Cupin_2; cl17218
767434005723	Rhamnan synthesis protein F; Region: RgpF; pfam05045
767434005724	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
767434005725	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
767434005726	hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13548
767434005727	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
767434005728	Walker A/P-loop; other site
767434005729	ATP binding site [chemical binding]; other site
767434005730	Q-loop/lid; other site
767434005731	ABC transporter signature motif; other site
767434005732	Walker B; other site
767434005733	D-loop; other site
767434005734	H-loop/switch region; other site
767434005735	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
767434005736	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
767434005737	dimer interface [polypeptide binding]; other site
767434005738	putative PBP binding regions; other site
767434005739	ABC-ATPase subunit  interface; other site
767434005740	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
767434005741	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
767434005742	intersubunit interface [polypeptide binding]; other site
767434005743	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
767434005744	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
767434005745	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
767434005746	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434005747	N-terminal plug; other site
767434005748	ligand-binding site [chemical binding]; other site
767434005749	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
767434005750	DNA-binding site [nucleotide binding]; DNA binding site
767434005751	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
767434005752	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
767434005753	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434005754	homodimer interface [polypeptide binding]; other site
767434005755	catalytic residue [active]
767434005756	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
767434005757	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
767434005758	active site
767434005759	multimer interface [polypeptide binding]; other site
767434005760	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
767434005761	predicted active site [active]
767434005762	catalytic triad [active]
767434005763	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434005764	putative substrate translocation pore; other site
767434005765	Major Facilitator Superfamily; Region: MFS_1; pfam07690
767434005766	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
767434005767	progesterone 5-beta-reductase-like proteins (5beta-POR), atypical (a) SDRs; Region: 5beta-POR_like_SDR_a; cd08948
767434005768	NAD(P) binding site [chemical binding]; other site
767434005769	active site
767434005770	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
767434005771	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434005772	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
767434005773	dimerization interface [polypeptide binding]; other site
767434005774	substrate binding pocket [chemical binding]; other site
767434005775	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; pfam01977
767434005776	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
767434005777	Flavoprotein; Region: Flavoprotein; pfam02441
767434005778	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
767434005779	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
767434005780	Metal-binding active site; metal-binding site
767434005781	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
767434005782	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434005783	putative substrate translocation pore; other site
767434005784	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3787; cl17897
767434005785	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
767434005786	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
767434005787	active site
767434005788	catalytic residue [active]
767434005789	dimer interface [polypeptide binding]; other site
767434005790	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
767434005791	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
767434005792	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
767434005793	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
767434005794	RimM N-terminal domain; Region: RimM; pfam01782
767434005795	PRC-barrel domain; Region: PRC; pfam05239
767434005796	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
767434005797	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
767434005798	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
767434005799	substrate binding pocket [chemical binding]; other site
767434005800	membrane-bound complex binding site; other site
767434005801	ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG4525
767434005802	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
767434005803	Walker A/P-loop; other site
767434005804	ATP binding site [chemical binding]; other site
767434005805	Q-loop/lid; other site
767434005806	ABC transporter signature motif; other site
767434005807	Walker B; other site
767434005808	D-loop; other site
767434005809	H-loop/switch region; other site
767434005810	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
767434005811	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
767434005812	dimer interface [polypeptide binding]; other site
767434005813	conserved gate region; other site
767434005814	putative PBP binding loops; other site
767434005815	ABC-ATPase subunit interface; other site
767434005816	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
767434005817	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
767434005818	signal recognition particle protein; Provisional; Region: PRK10867
767434005819	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
767434005820	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
767434005821	P loop; other site
767434005822	GTP binding site [chemical binding]; other site
767434005823	Signal peptide binding domain; Region: SRP_SPB; pfam02978
767434005824	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
767434005825	catalytic residues [active]
767434005826	Disulphide bond corrector protein DsbC; Region: DsbC; cl15830
767434005827	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
767434005828	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
767434005829	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
767434005830	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
767434005831	putative active site [active]
767434005832	putative substrate binding site [chemical binding]; other site
767434005833	putative cosubstrate binding site; other site
767434005834	catalytic site [active]
767434005835	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
767434005836	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
767434005837	C-terminal domain interface [polypeptide binding]; other site
767434005838	GSH binding site (G-site) [chemical binding]; other site
767434005839	dimer interface [polypeptide binding]; other site
767434005840	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
767434005841	dimer interface [polypeptide binding]; other site
767434005842	N-terminal domain interface [polypeptide binding]; other site
767434005843	substrate binding pocket (H-site) [chemical binding]; other site
767434005844	RNA polymerase-binding protein DksA; Region: dksA; TIGR02420
767434005845	Haemolytic domain; Region: Haemolytic; pfam01809
767434005846	dihydroorotase; Reviewed; Region: PRK09236
767434005847	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
767434005848	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
767434005849	active site
767434005850	Protein of unknown function (DUF3014); Region: DUF3014; pfam11219
767434005851	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
767434005852	dinuclear metal binding motif [ion binding]; other site
767434005853	amidophosphoribosyltransferase; Provisional; Region: PRK09246
767434005854	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
767434005855	active site
767434005856	tetramer interface [polypeptide binding]; other site
767434005857	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
767434005858	active site
767434005859	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
767434005860	Colicin V production protein; Region: Colicin_V; pfam02674
767434005861	Sporulation related domain; Region: SPOR; pfam05036
767434005862	Sporulation related domain; Region: SPOR; cl10051
767434005863	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
767434005864	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
767434005865	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
767434005866	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
767434005867	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
767434005868	active site
767434005869	ribulose/triose binding site [chemical binding]; other site
767434005870	phosphate binding site [ion binding]; other site
767434005871	substrate (anthranilate) binding pocket [chemical binding]; other site
767434005872	product (indole) binding pocket [chemical binding]; other site
767434005873	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
767434005874	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
767434005875	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
767434005876	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
767434005877	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
767434005878	glutamine binding [chemical binding]; other site
767434005879	catalytic triad [active]
767434005880	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
767434005881	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
767434005882	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
767434005883	Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; Region: Fiu; COG4774
767434005884	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434005885	N-terminal plug; other site
767434005886	ligand-binding site [chemical binding]; other site
767434005887	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
767434005888	putative metal binding site [ion binding]; other site
767434005889	putative homodimer interface [polypeptide binding]; other site
767434005890	S-formylglutathione hydrolase; Region: PLN02442
767434005891	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
767434005892	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
767434005893	Peptidase family M1; Region: Peptidase_M1; pfam01433
767434005894	Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); Region: M1_APN_2; cd09601
767434005895	Zn binding site [ion binding]; other site
767434005896	Domain of unknown function (DUF3358); Region: DUF3358; pfam11838
767434005897	NAD-dependent deacetylase; Provisional; Region: PRK05333
767434005898	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
767434005899	Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimT; COG4970
767434005900	Type II transport protein GspH; Region: GspH; pfam12019
767434005901	Tfp pilus assembly protein PilE [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilE; COG4968
767434005902	Tfp pilus assembly protein, tip-associated adhesin PilY1 [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilY1; COG3419
767434005903	Neisseria PilC beta-propeller domain; Region: Neisseria_PilC; pfam05567
767434005904	Tfp pilus assembly protein PilX [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilX; COG4726
767434005905	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
767434005906	type IV pilus modification protein PilV; Region: type_IV_pilV; TIGR02523
767434005907	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
767434005908	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
767434005909	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
767434005910	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
767434005911	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
767434005912	active site
767434005913	HIGH motif; other site
767434005914	KMSKS motif; other site
767434005915	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
767434005916	tRNA binding surface [nucleotide binding]; other site
767434005917	anticodon binding site; other site
767434005918	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
767434005919	dimer interface [polypeptide binding]; other site
767434005920	putative tRNA-binding site [nucleotide binding]; other site
767434005921	inner membrane protein; Provisional; Region: PRK10995
767434005922	ferredoxin; Provisional; Region: PRK08764
767434005923	Putative Fe-S cluster; Region: FeS; pfam04060
767434005924	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
767434005925	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
767434005926	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
767434005927	minor groove reading motif; other site
767434005928	helix-hairpin-helix signature motif; other site
767434005929	substrate binding pocket [chemical binding]; other site
767434005930	active site
767434005931	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
767434005932	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
767434005933	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
767434005934	Sel1-like repeats; Region: SEL1; smart00671
767434005935	Sel1-like repeats; Region: SEL1; smart00671
767434005936	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
767434005937	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
767434005938	Beta-lactamase; Region: Beta-lactamase; pfam00144
767434005939	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
767434005940	Uncharacterized conserved protein [Function unknown]; Region: COG1739
767434005941	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
767434005942	SurA N-terminal domain; Region: SurA_N_3; cl07813
767434005943	periplasmic folding chaperone; Provisional; Region: PRK10788
767434005944	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
767434005945	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
767434005946	IHF dimer interface [polypeptide binding]; other site
767434005947	IHF - DNA interface [nucleotide binding]; other site
767434005948	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
767434005949	Found in ATP-dependent protease La (LON); Region: LON; smart00464
767434005950	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434005951	Walker A motif; other site
767434005952	ATP binding site [chemical binding]; other site
767434005953	Walker B motif; other site
767434005954	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
767434005955	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
767434005956	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
767434005957	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434005958	Walker A motif; other site
767434005959	ATP binding site [chemical binding]; other site
767434005960	Walker B motif; other site
767434005961	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
767434005962	Clp protease; Region: CLP_protease; pfam00574
767434005963	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
767434005964	oligomer interface [polypeptide binding]; other site
767434005965	active site residues [active]
767434005966	trigger factor; Provisional; Region: tig; PRK01490
767434005967	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
767434005968	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
767434005969	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
767434005970	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
767434005971	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434005972	Walker A/P-loop; other site
767434005973	ATP binding site [chemical binding]; other site
767434005974	Q-loop/lid; other site
767434005975	ABC transporter signature motif; other site
767434005976	Walker B; other site
767434005977	D-loop; other site
767434005978	H-loop/switch region; other site
767434005979	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: COG3264
767434005980	Protein of unknown function (DUF3772); Region: DUF3772; pfam12607
767434005981	Mechanosensitive ion channel; Region: MS_channel; pfam00924
767434005982	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
767434005983	Predicted 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG1023
767434005984	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
767434005985	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
767434005986	Predicted transcriptional regulator [Transcription]; Region: COG1959
767434005987	Transcriptional regulator; Region: Rrf2; pfam02082
767434005988	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK08261
767434005989	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434005990	NAD(P) binding site [chemical binding]; other site
767434005991	active site
767434005992	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
767434005993	active site 2 [active]
767434005994	active site 1 [active]
767434005995	acetyl-CoA acetyltransferase; Provisional; Region: PRK09268
767434005996	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
767434005997	dimer interface [polypeptide binding]; other site
767434005998	active site
767434005999	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
767434006000	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434006001	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
767434006002	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
767434006003	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434006004	NAD(P) binding site [chemical binding]; other site
767434006005	active site
767434006006	transcriptional regulator; Provisional; Region: PRK10632
767434006007	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434006008	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
767434006009	putative effector binding pocket; other site
767434006010	dimerization interface [polypeptide binding]; other site
767434006011	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
767434006012	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
767434006013	catalytic site [active]
767434006014	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
767434006015	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
767434006016	putative acyl-acceptor binding pocket; other site
767434006017	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
767434006018	MarC family integral membrane protein; Region: MarC; cl00919
767434006019	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
767434006020	superoxide dismutase; Provisional; Region: PRK10543
767434006021	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
767434006022	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
767434006023	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
767434006024	ATP-grasp domain; Region: ATP-grasp; pfam02222
767434006025	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
767434006026	Trm112p-like protein; Region: Trm112p; cl01066
767434006027	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
767434006028	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
767434006029	dimerization interface [polypeptide binding]; other site
767434006030	active site
767434006031	Protein of unknown function (DUF3301); Region: DUF3301; pfam11743
767434006032	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
767434006033	Cytochrome c; Region: Cytochrom_C; cl11414
767434006034	Cytochrome C1 family; Region: Cytochrom_C1; pfam02167
767434006035	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
767434006036	Qi binding site; other site
767434006037	intrachain domain interface; other site
767434006038	interchain domain interface [polypeptide binding]; other site
767434006039	heme bH binding site [chemical binding]; other site
767434006040	heme bL binding site [chemical binding]; other site
767434006041	Qo binding site; other site
767434006042	Cytochrome b(C-terminus)/b6/petD:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: cytochrome_b_C; cl00193
767434006043	interchain domain interface [polypeptide binding]; other site
767434006044	intrachain domain interface; other site
767434006045	Qi binding site; other site
767434006046	Qo binding site; other site
767434006047	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
767434006048	Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470
767434006049	[2Fe-2S] cluster binding site [ion binding]; other site
767434006050	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
767434006051	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
767434006052	protein binding site [polypeptide binding]; other site
767434006053	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
767434006054	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
767434006055	N-acetyl-D-glucosamine binding site [chemical binding]; other site
767434006056	catalytic residue [active]
767434006057	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
767434006058	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
767434006059	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
767434006060	FeS/SAM binding site; other site
767434006061	TRAM domain; Region: TRAM; pfam01938
767434006062	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
767434006063	PhoH-like protein; Region: PhoH; pfam02562
767434006064	metal-binding heat shock protein; Provisional; Region: PRK00016
767434006065	Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism]; Region: CorC; COG4535
767434006066	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
767434006067	Transporter associated domain; Region: CorC_HlyC; smart01091
767434006068	Domain of unknown function (DUF4105); Region: DUF4105; pfam13387
767434006069	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
767434006070	Mycobacterium tuberculosis CorA-like subfamily; Region: MtCorA-like; cd12830
767434006071	oligomer interface [polypeptide binding]; other site
767434006072	metal binding site [ion binding]; metal-binding site
767434006073	metal binding site [ion binding]; metal-binding site
767434006074	putative Cl binding site [ion binding]; other site
767434006075	basic sphincter; other site
767434006076	hydrophobic gate; other site
767434006077	periplasmic entrance; other site
767434006078	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
767434006079	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
767434006080	Pilin (bacterial filament); Region: Pilin; pfam00114
767434006081	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
767434006082	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
767434006083	catalytic core [active]
767434006084	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
767434006085	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
767434006086	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
767434006087	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
767434006088	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
767434006089	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
767434006090	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434006091	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434006092	metal binding site [ion binding]; metal-binding site
767434006093	active site
767434006094	I-site; other site
767434006095	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
767434006096	Protein of unknown function (DUF3667); Region: DUF3667; pfam12412
767434006097	ATP-dependent Clp protease proteolytic subunit; Provisional; Region: PRK14512
767434006098	chromosome condensation membrane protein; Provisional; Region: PRK14196
767434006099	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
767434006100	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
767434006101	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
767434006102	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434006103	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
767434006104	classical (c) SDRs; Region: SDR_c; cd05233
767434006105	NAD(P) binding site [chemical binding]; other site
767434006106	active site
767434006107	short chain dehydrogenase; Provisional; Region: PRK06180
767434006108	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
767434006109	NADP binding site [chemical binding]; other site
767434006110	active site
767434006111	steroid binding site; other site
767434006112	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
767434006113	Predicted transcriptional regulators [Transcription]; Region: COG1733
767434006114	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
767434006115	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
767434006116	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434006117	NAD(P) binding site [chemical binding]; other site
767434006118	active site
767434006119	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434006120	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434006121	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
767434006122	putative effector binding pocket; other site
767434006123	putative dimerization interface [polypeptide binding]; other site
767434006124	phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs; Region: PCBER_SDR_a; cd05259
767434006125	NAD(P) binding site [chemical binding]; other site
767434006126	active site lysine
767434006127	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
767434006128	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
767434006129	Coenzyme A binding pocket [chemical binding]; other site
767434006130	Cytochrome c; Region: Cytochrom_C; pfam00034
767434006131	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434006132	Cytochrome c; Region: Cytochrom_C; pfam00034
767434006133	Cytochrome c; Region: Cytochrom_C; pfam00034
767434006134	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
767434006135	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
767434006136	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
767434006137	Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318
767434006138	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
767434006139	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
767434006140	Trp docking motif [polypeptide binding]; other site
767434006141	putative active site [active]
767434006142	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
767434006143	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
767434006144	Trp docking motif [polypeptide binding]; other site
767434006145	putative active site [active]
767434006146	RNA polymerase sigma factor; Provisional; Region: PRK12512
767434006147	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
767434006148	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
767434006149	DNA binding residues [nucleotide binding]
767434006150	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
767434006151	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
767434006152	DsbD alpha interface [polypeptide binding]; other site
767434006153	catalytic residues [active]
767434006154	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
767434006155	catalytic triad [active]
767434006156	Right handed beta helix region; Region: Beta_helix; pfam13229
767434006157	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
767434006158	putative deacylase active site [active]
767434006159	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cl00234
767434006160	active site
767434006161	catalytic residues [active]
767434006162	metal binding site [ion binding]; metal-binding site
767434006163	Initiator Replication protein; Region: Rep_3; pfam01051
767434006164	aromatic amino acid exporter; Provisional; Region: PRK11689
767434006165	myosin-cross-reactive antigen; Provisional; Region: PRK13977
767434006166	hypothetical protein; Provisional; Region: PRK02237
767434006167	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
767434006168	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
767434006169	active site
767434006170	Zn binding site [ion binding]; other site
767434006171	seryl-tRNA synthetase; Provisional; Region: PRK05431
767434006172	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
767434006173	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
767434006174	dimer interface [polypeptide binding]; other site
767434006175	active site
767434006176	motif 1; other site
767434006177	motif 2; other site
767434006178	motif 3; other site
767434006179	recombination factor protein RarA; Reviewed; Region: PRK13342
767434006180	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434006181	Walker A motif; other site
767434006182	ATP binding site [chemical binding]; other site
767434006183	Walker B motif; other site
767434006184	arginine finger; other site
767434006185	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
767434006186	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
767434006187	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434006188	dimer interface [polypeptide binding]; other site
767434006189	phosphorylation site [posttranslational modification]
767434006190	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
767434006191	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
767434006192	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434006193	active site
767434006194	phosphorylation site [posttranslational modification]
767434006195	intermolecular recognition site; other site
767434006196	dimerization interface [polypeptide binding]; other site
767434006197	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
767434006198	DNA binding site [nucleotide binding]
767434006199	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
767434006200	active site
767434006201	catalytic triad [active]
767434006202	oxyanion hole [active]
767434006203	switch loop; other site
767434006204	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG4181
767434006205	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
767434006206	Walker A/P-loop; other site
767434006207	ATP binding site [chemical binding]; other site
767434006208	Q-loop/lid; other site
767434006209	ABC transporter signature motif; other site
767434006210	Walker B; other site
767434006211	D-loop; other site
767434006212	H-loop/switch region; other site
767434006213	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
767434006214	FtsX-like permease family; Region: FtsX; pfam02687
767434006215	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
767434006216	nucleotide binding site [chemical binding]; other site
767434006217	putative NEF/HSP70 interaction site [polypeptide binding]; other site
767434006218	SBD interface [polypeptide binding]; other site
767434006219	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
767434006220	transmembrane helices; other site
767434006221	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
767434006222	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
767434006223	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
767434006224	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
767434006225	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
767434006226	homodimer interface [polypeptide binding]; other site
767434006227	metal binding site [ion binding]; metal-binding site
767434006228	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
767434006229	homodimer interface [polypeptide binding]; other site
767434006230	active site
767434006231	putative chemical substrate binding site [chemical binding]; other site
767434006232	metal binding site [ion binding]; metal-binding site
767434006233	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
767434006234	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
767434006235	active site
767434006236	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
767434006237	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
767434006238	dimer interface [polypeptide binding]; other site
767434006239	ADP-ribose binding site [chemical binding]; other site
767434006240	active site
767434006241	nudix motif; other site
767434006242	metal binding site [ion binding]; metal-binding site
767434006243	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
767434006244	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
767434006245	active site
767434006246	Type II secretion system (T2SS), protein N; Region: T2SN; pfam01203
767434006247	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK07030
767434006248	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
767434006249	inhibitor-cofactor binding pocket; inhibition site
767434006250	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434006251	catalytic residue [active]
767434006252	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
767434006253	RNA methyltransferase, RsmE family; Region: TIGR00046
767434006254	glutathione synthetase; Provisional; Region: PRK05246
767434006255	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
767434006256	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
767434006257	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
767434006258	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
767434006259	hypothetical protein; Validated; Region: PRK00228
767434006260	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
767434006261	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
767434006262	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
767434006263	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
767434006264	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434006265	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434006266	N-terminal plug; other site
767434006267	ligand-binding site [chemical binding]; other site
767434006268	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
767434006269	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434006270	N-terminal plug; other site
767434006271	ligand-binding site [chemical binding]; other site
767434006272	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
767434006273	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
767434006274	active site
767434006275	dimerization interface [polypeptide binding]; other site
767434006276	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
767434006277	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
767434006278	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
767434006279	Domain of unknown function DUF21; Region: DUF21; pfam01595
767434006280	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
767434006281	Transporter associated domain; Region: CorC_HlyC; smart01091
767434006282	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
767434006283	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
767434006284	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
767434006285	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
767434006286	motif II; other site
767434006287	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
767434006288	active site
767434006289	DNA binding site [nucleotide binding]
767434006290	PQQ-dependent dehydrogenase, methanol/ethanol family; Region: PQQ_enz_alc_DH; TIGR03075
767434006291	PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); Region: PQQ_ADH_II; cd10279
767434006292	Trp docking motif [polypeptide binding]; other site
767434006293	cytochrome domain interface [polypeptide binding]; other site
767434006294	active site
767434006295	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434006296	Cytochrome c; Region: Cytochrom_C; pfam00034
767434006297	Cytochrome c; Region: Cytochrom_C; pfam00034
767434006298	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434006299	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434006300	Cytochrome c; Region: Cytochrom_C; pfam00034
767434006301	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
767434006302	PhoU domain; Region: PhoU; pfam01895
767434006303	PhoU domain; Region: PhoU; pfam01895
767434006304	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
767434006305	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
767434006306	Walker A/P-loop; other site
767434006307	ATP binding site [chemical binding]; other site
767434006308	Q-loop/lid; other site
767434006309	ABC transporter signature motif; other site
767434006310	Walker B; other site
767434006311	D-loop; other site
767434006312	H-loop/switch region; other site
767434006313	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
767434006314	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
767434006315	dimer interface [polypeptide binding]; other site
767434006316	conserved gate region; other site
767434006317	putative PBP binding loops; other site
767434006318	ABC-ATPase subunit interface; other site
767434006319	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
767434006320	dimer interface [polypeptide binding]; other site
767434006321	conserved gate region; other site
767434006322	putative PBP binding loops; other site
767434006323	ABC-ATPase subunit interface; other site
767434006324	PBP superfamily domain; Region: PBP_like_2; cl17296
767434006325	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
767434006326	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
767434006327	dimer interface [polypeptide binding]; other site
767434006328	catalytic site [active]
767434006329	putative active site [active]
767434006330	putative substrate binding site [chemical binding]; other site
767434006331	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
767434006332	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
767434006333	Tetratricopeptide repeat; Region: TPR_16; pfam13432
767434006334	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434006335	binding surface
767434006336	TPR motif; other site
767434006337	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434006338	binding surface
767434006339	Tetratricopeptide repeat; Region: TPR_16; pfam13432
767434006340	TPR motif; other site
767434006341	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
767434006342	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
767434006343	endo-1,4-D-glucanase; Provisional; Region: PRK11097
767434006344	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
767434006345	cellulose synthase catalytic subunit (UDP-forming); Region: CelA; TIGR03030
767434006346	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
767434006347	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
767434006348	DXD motif; other site
767434006349	PilZ domain; Region: PilZ; pfam07238
767434006350	Cellulose synthase subunit D; Region: Cellsynth_D; pfam03500
767434006351	Glycosyl hydrolases family 8; Region: Glyco_hydro_8; cl01351
767434006352	Glycosyl hydrolases family 8; Region: Glyco_hydro_8; cl01351
767434006353	Protein of unknown function (DUF2819); Region: DUF2819; cl17862
767434006354	Protein of unknown function (DUF3260); Region: DUF3260; cl11881
767434006355	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
767434006356	YhjQ protein; Region: YhjQ; pfam06564
767434006357	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
767434006358	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
767434006359	DXD motif; other site
767434006360	PilZ domain; Region: PilZ; pfam07238
767434006361	cellulose synthase regulator protein; Provisional; Region: PRK11114
767434006362	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
767434006363	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434006364	binding surface
767434006365	TPR motif; other site
767434006366	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434006367	binding surface
767434006368	TPR motif; other site
767434006369	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
767434006370	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
767434006371	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
767434006372	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
767434006373	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434006374	active site
767434006375	phosphorylation site [posttranslational modification]
767434006376	intermolecular recognition site; other site
767434006377	dimerization interface [polypeptide binding]; other site
767434006378	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
767434006379	DNA binding residues [nucleotide binding]
767434006380	dimerization interface [polypeptide binding]; other site
767434006381	Histidine kinase; Region: HisKA_3; pfam07730
767434006382	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434006383	ATP binding site [chemical binding]; other site
767434006384	Mg2+ binding site [ion binding]; other site
767434006385	G-X-G motif; other site
767434006386	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
767434006387	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
767434006388	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
767434006389	catalytic residue [active]
767434006390	psiF repeat; Region: PsiF_repeat; pfam07769
767434006391	psiF repeat; Region: PsiF_repeat; pfam07769
767434006392	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
767434006393	active site
767434006394	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
767434006395	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
767434006396	TAP-like protein; Region: Abhydrolase_4; pfam08386
767434006397	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
767434006398	FAD binding domain; Region: FAD_binding_4; pfam01565
767434006399	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
767434006400	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
767434006401	ligand binding site [chemical binding]; other site
767434006402	NAD binding site [chemical binding]; other site
767434006403	tetramer interface [polypeptide binding]; other site
767434006404	catalytic site [active]
767434006405	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
767434006406	L-serine binding site [chemical binding]; other site
767434006407	ACT domain interface; other site
767434006408	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434006409	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434006410	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
767434006411	dimerization interface [polypeptide binding]; other site
767434006412	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
767434006413	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
767434006414	substrate binding site [chemical binding]; other site
767434006415	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
767434006416	substrate binding site [chemical binding]; other site
767434006417	ligand binding site [chemical binding]; other site
767434006418	aconitate hydratase; Validated; Region: PRK09277
767434006419	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
767434006420	substrate binding site [chemical binding]; other site
767434006421	ligand binding site [chemical binding]; other site
767434006422	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
767434006423	substrate binding site [chemical binding]; other site
767434006424	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism]; Region: FhuE; COG4773
767434006425	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434006426	N-terminal plug; other site
767434006427	ligand-binding site [chemical binding]; other site
767434006428	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434006429	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434006430	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
767434006431	putative effector binding pocket; other site
767434006432	dimerization interface [polypeptide binding]; other site
767434006433	Predicted membrane protein [Function unknown]; Region: COG2259
767434006434	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
767434006435	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
767434006436	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434006437	N-terminal plug; other site
767434006438	ligand-binding site [chemical binding]; other site
767434006439	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
767434006440	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434006441	putative substrate translocation pore; other site
767434006442	Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939
767434006443	Serine carboxypeptidase; Region: Peptidase_S10; cl08270
767434006444	putative arabinose transporter; Provisional; Region: PRK03545
767434006445	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434006446	putative substrate translocation pore; other site
767434006447	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434006448	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434006449	metal binding site [ion binding]; metal-binding site
767434006450	active site
767434006451	I-site; other site
767434006452	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
767434006453	MutS domain I; Region: MutS_I; pfam01624
767434006454	MutS domain II; Region: MutS_II; pfam05188
767434006455	MutS domain III; Region: MutS_III; pfam05192
767434006456	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
767434006457	Walker A/P-loop; other site
767434006458	ATP binding site [chemical binding]; other site
767434006459	Q-loop/lid; other site
767434006460	ABC transporter signature motif; other site
767434006461	Walker B; other site
767434006462	D-loop; other site
767434006463	H-loop/switch region; other site
767434006464	Uncharacterized subfamily of Uracil-DNA glycosylases; Region: UDG_like_1; cd10033
767434006465	putative uracil binding site [chemical binding]; other site
767434006466	putative active site [active]
767434006467	tryptophanyl-tRNA synthetase; Reviewed; Region: PRK12284
767434006468	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
767434006469	active site
767434006470	HIGH motif; other site
767434006471	dimer interface [polypeptide binding]; other site
767434006472	KMSKS motif; other site
767434006473	agmatinase; Region: agmatinase; TIGR01230
767434006474	Arginase family; Region: Arginase; cd09989
767434006475	active site
767434006476	Mn binding site [ion binding]; other site
767434006477	oligomer interface [polypeptide binding]; other site
767434006478	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3825
767434006479	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
767434006480	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434006481	Walker A motif; other site
767434006482	ATP binding site [chemical binding]; other site
767434006483	Walker B motif; other site
767434006484	arginine finger; other site
767434006485	Predicted membrane protein (DUF2127); Region: DUF2127; pfam09900
767434006486	EamA-like transporter family; Region: EamA; pfam00892
767434006487	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
767434006488	EamA-like transporter family; Region: EamA; pfam00892
767434006489	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
767434006490	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
767434006491	Probable Catalytic site; other site
767434006492	metal-binding site
767434006493	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
767434006494	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
767434006495	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
767434006496	dimerization interface [polypeptide binding]; other site
767434006497	ATP binding site [chemical binding]; other site
767434006498	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
767434006499	dimerization interface [polypeptide binding]; other site
767434006500	ATP binding site [chemical binding]; other site
767434006501	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
767434006502	putative active site [active]
767434006503	catalytic triad [active]
767434006504	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
767434006505	dimerization domain [polypeptide binding]; other site
767434006506	dimer interface [polypeptide binding]; other site
767434006507	catalytic residues [active]
767434006508	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
767434006509	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
767434006510	active site
767434006511	DNA binding site [nucleotide binding]
767434006512	Int/Topo IB signature motif; other site
767434006513	RDD family; Region: RDD; pfam06271
767434006514	Poly-beta-hydroxyalkanoate depolymerase [Lipid metabolism]; Region: DepA; COG4553
767434006515	PHB de-polymerase C-terminus; Region: PHB_depo_C; pfam06850
767434006516	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
767434006517	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
767434006518	tetramer interface [polypeptide binding]; other site
767434006519	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434006520	catalytic residue [active]
767434006521	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
767434006522	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
767434006523	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
767434006524	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
767434006525	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
767434006526	multifunctional aminopeptidase A; Provisional; Region: PRK00913
767434006527	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
767434006528	interface (dimer of trimers) [polypeptide binding]; other site
767434006529	Substrate-binding/catalytic site; other site
767434006530	Zn-binding sites [ion binding]; other site
767434006531	DNA polymerase III chi subunit, HolC; Region: DNA_pol3_chi; pfam04364
767434006532	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434006533	dimer interface [polypeptide binding]; other site
767434006534	phosphorylation site [posttranslational modification]
767434006535	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434006536	ATP binding site [chemical binding]; other site
767434006537	Mg2+ binding site [ion binding]; other site
767434006538	G-X-G motif; other site
767434006539	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
767434006540	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
767434006541	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
767434006542	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
767434006543	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
767434006544	elongation factor G; Reviewed; Region: PRK00007
767434006545	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
767434006546	G1 box; other site
767434006547	GTP/Mg2+ binding site [chemical binding]; other site
767434006548	G2 box; other site
767434006549	Switch I region; other site
767434006550	G3 box; other site
767434006551	Switch II region; other site
767434006552	G4 box; other site
767434006553	G5 box; other site
767434006554	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
767434006555	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
767434006556	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
767434006557	M20 Peptidase, carboxypeptidase yscS-like; Region: M20_yscS_like; cd05675
767434006558	hypothetical protein; Provisional; Region: PRK09133
767434006559	putative metal binding site [ion binding]; other site
767434006560	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
767434006561	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
767434006562	G1 box; other site
767434006563	putative GEF interaction site [polypeptide binding]; other site
767434006564	GTP/Mg2+ binding site [chemical binding]; other site
767434006565	Switch I region; other site
767434006566	G2 box; other site
767434006567	G3 box; other site
767434006568	Switch II region; other site
767434006569	G4 box; other site
767434006570	G5 box; other site
767434006571	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
767434006572	CHASE3 domain; Region: CHASE3; pfam05227
767434006573	HAMP domain; Region: HAMP; pfam00672
767434006574	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
767434006575	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434006576	dimer interface [polypeptide binding]; other site
767434006577	phosphorylation site [posttranslational modification]
767434006578	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434006579	ATP binding site [chemical binding]; other site
767434006580	Mg2+ binding site [ion binding]; other site
767434006581	G-X-G motif; other site
767434006582	Response regulator receiver domain; Region: Response_reg; pfam00072
767434006583	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434006584	active site
767434006585	phosphorylation site [posttranslational modification]
767434006586	intermolecular recognition site; other site
767434006587	dimerization interface [polypeptide binding]; other site
767434006588	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
767434006589	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434006590	active site
767434006591	phosphorylation site [posttranslational modification]
767434006592	intermolecular recognition site; other site
767434006593	dimerization interface [polypeptide binding]; other site
767434006594	Response regulator receiver domain; Region: Response_reg; pfam00072
767434006595	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434006596	active site
767434006597	phosphorylation site [posttranslational modification]
767434006598	intermolecular recognition site; other site
767434006599	dimerization interface [polypeptide binding]; other site
767434006600	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
767434006601	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
767434006602	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
767434006603	CheB methylesterase; Region: CheB_methylest; pfam01339
767434006604	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
767434006605	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434006606	active site
767434006607	phosphorylation site [posttranslational modification]
767434006608	intermolecular recognition site; other site
767434006609	dimerization interface [polypeptide binding]; other site
767434006610	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434006611	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434006612	metal binding site [ion binding]; metal-binding site
767434006613	active site
767434006614	I-site; other site
767434006615	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
767434006616	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
767434006617	FMN binding site [chemical binding]; other site
767434006618	active site
767434006619	catalytic residues [active]
767434006620	substrate binding site [chemical binding]; other site
767434006621	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
767434006622	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434006623	active site
767434006624	phosphorylation site [posttranslational modification]
767434006625	intermolecular recognition site; other site
767434006626	dimerization interface [polypeptide binding]; other site
767434006627	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
767434006628	DNA binding site [nucleotide binding]
767434006629	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
767434006630	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434006631	dimer interface [polypeptide binding]; other site
767434006632	phosphorylation site [posttranslational modification]
767434006633	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434006634	ATP binding site [chemical binding]; other site
767434006635	Mg2+ binding site [ion binding]; other site
767434006636	G-X-G motif; other site
767434006637	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
767434006638	putative DNA binding site [nucleotide binding]; other site
767434006639	dimerization interface [polypeptide binding]; other site
767434006640	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
767434006641	putative Zn2+ binding site [ion binding]; other site
767434006642	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
767434006643	Type III pantothenate kinase; Region: Pan_kinase; pfam03309
767434006644	Long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07059
767434006645	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
767434006646	acyl-activating enzyme (AAE) consensus motif; other site
767434006647	putative AMP binding site [chemical binding]; other site
767434006648	putative active site [active]
767434006649	putative CoA binding site [chemical binding]; other site
767434006650	Rec8/ScpA/Scc1-like protein (kleisin family) [Replication,    recombination, and repair]; Region: scpA; COG1354
767434006651	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
767434006652	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
767434006653	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
767434006654	RNA binding surface [nucleotide binding]; other site
767434006655	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
767434006656	probable active site [active]
767434006657	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
767434006658	ArsC family; Region: ArsC; pfam03960
767434006659	catalytic residues [active]
767434006660	C-N hydrolase family amidase; Provisional; Region: PRK10438
767434006661	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
767434006662	putative active site [active]
767434006663	catalytic triad [active]
767434006664	dimer interface [polypeptide binding]; other site
767434006665	multimer interface [polypeptide binding]; other site
767434006666	methionine aminotransferase; Validated; Region: PRK09082
767434006667	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
767434006668	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434006669	homodimer interface [polypeptide binding]; other site
767434006670	catalytic residue [active]
767434006671	LysR family transcriptional regulator; Provisional; Region: PRK14997
767434006672	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434006673	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
767434006674	putative effector binding pocket; other site
767434006675	putative dimerization interface [polypeptide binding]; other site
767434006676	Protein of unknown function (DUF2846); Region: DUF2846; pfam11008
767434006677	Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg2; cd04765
767434006678	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
767434006679	DNA binding residues [nucleotide binding]
767434006680	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
767434006681	IHF - DNA interface [nucleotide binding]; other site
767434006682	IHF dimer interface [polypeptide binding]; other site
767434006683	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
767434006684	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
767434006685	putative tRNA-binding site [nucleotide binding]; other site
767434006686	B3/4 domain; Region: B3_4; pfam03483
767434006687	tRNA synthetase B5 domain; Region: B5; smart00874
767434006688	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
767434006689	dimer interface [polypeptide binding]; other site
767434006690	motif 1; other site
767434006691	motif 3; other site
767434006692	motif 2; other site
767434006693	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
767434006694	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
767434006695	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
767434006696	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
767434006697	dimer interface [polypeptide binding]; other site
767434006698	motif 1; other site
767434006699	active site
767434006700	motif 2; other site
767434006701	motif 3; other site
767434006702	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
767434006703	23S rRNA binding site [nucleotide binding]; other site
767434006704	L21 binding site [polypeptide binding]; other site
767434006705	L13 binding site [polypeptide binding]; other site
767434006706	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
767434006707	translation initiation factor IF-3; Region: infC; TIGR00168
767434006708	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
767434006709	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
767434006710	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
767434006711	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
767434006712	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
767434006713	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
767434006714	active site
767434006715	dimer interface [polypeptide binding]; other site
767434006716	motif 1; other site
767434006717	motif 2; other site
767434006718	motif 3; other site
767434006719	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
767434006720	anticodon binding site; other site
767434006721	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
767434006722	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
767434006723	putative NAD(P) binding site [chemical binding]; other site
767434006724	active site
767434006725	putative substrate binding site [chemical binding]; other site
767434006726	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434006727	malonic semialdehyde reductase; Provisional; Region: PRK10538
767434006728	NAD(P) binding site [chemical binding]; other site
767434006729	active site
767434006730	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
767434006731	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
767434006732	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
767434006733	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
767434006734	active site
767434006735	intersubunit interface [polypeptide binding]; other site
767434006736	catalytic residue [active]
767434006737	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
767434006738	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434006739	putative substrate translocation pore; other site
767434006740	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434006741	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144
767434006742	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
767434006743	dimerization interface [polypeptide binding]; other site
767434006744	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
767434006745	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
767434006746	dimer interface [polypeptide binding]; other site
767434006747	putative CheW interface [polypeptide binding]; other site
767434006748	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cd02106
767434006749	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434006750	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434006751	metal binding site [ion binding]; metal-binding site
767434006752	active site
767434006753	I-site; other site
767434006754	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434006755	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434006756	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_2; cd06216
767434006757	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
767434006758	FAD binding pocket [chemical binding]; other site
767434006759	FAD binding motif [chemical binding]; other site
767434006760	phosphate binding motif [ion binding]; other site
767434006761	beta-alpha-beta structure motif; other site
767434006762	NAD binding pocket [chemical binding]; other site
767434006763	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
767434006764	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
767434006765	catalytic loop [active]
767434006766	iron binding site [ion binding]; other site
767434006767	Fatty acid desaturase; Region: FA_desaturase; pfam00487
767434006768	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
767434006769	putative di-iron ligands [ion binding]; other site
767434006770	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
767434006771	Helix-turn-helix domain; Region: HTH_38; pfam13936
767434006772	Integrase core domain; Region: rve; pfam00665
767434006773	excinuclease ABC subunit B; Provisional; Region: PRK05298
767434006774	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
767434006775	ATP binding site [chemical binding]; other site
767434006776	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
767434006777	nucleotide binding region [chemical binding]; other site
767434006778	ATP-binding site [chemical binding]; other site
767434006779	Ultra-violet resistance protein B; Region: UvrB; pfam12344
767434006780	UvrB/uvrC motif; Region: UVR; pfam02151
767434006781	Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimT; COG4970
767434006782	Type II transport protein GspH; Region: GspH; pfam12019
767434006783	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
767434006784	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
767434006785	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
767434006786	shikimate binding site; other site
767434006787	NAD(P) binding site [chemical binding]; other site
767434006788	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
767434006789	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
767434006790	Coenzyme A binding pocket [chemical binding]; other site
767434006791	SapC; Region: SapC; pfam07277
767434006792	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
767434006793	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
767434006794	active site
767434006795	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
767434006796	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
767434006797	TPP-binding site; other site
767434006798	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
767434006799	PYR/PP interface [polypeptide binding]; other site
767434006800	dimer interface [polypeptide binding]; other site
767434006801	TPP binding site [chemical binding]; other site
767434006802	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
767434006803	hopanoid biosynthesis associated RND transporter like protein HpnN; Region: HpnN; TIGR03480
767434006804	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
767434006805	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434006806	S-adenosylmethionine binding site [chemical binding]; other site
767434006807	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
767434006808	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434006809	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
767434006810	dimerization interface [polypeptide binding]; other site
767434006811	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
767434006812	active site
767434006813	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
767434006814	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
767434006815	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
767434006816	active site
767434006817	HIGH motif; other site
767434006818	nucleotide binding site [chemical binding]; other site
767434006819	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
767434006820	KMSKS motif; other site
767434006821	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
767434006822	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
767434006823	nucleoside/Zn binding site; other site
767434006824	dimer interface [polypeptide binding]; other site
767434006825	catalytic motif [active]
767434006826	Uncharacterized conserved protein [Function unknown]; Region: COG0398
767434006827	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
767434006828	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
767434006829	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
767434006830	GDP-binding site [chemical binding]; other site
767434006831	ACT binding site; other site
767434006832	IMP binding site; other site
767434006833	Uncharacterized protein conserved in bacteria (DUF2065); Region: DUF2065; cl01275
767434006834	HflC protein; Region: hflC; TIGR01932
767434006835	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
767434006836	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
767434006837	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
767434006838	HflK protein; Region: hflK; TIGR01933
767434006839	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
767434006840	RibD C-terminal domain; Region: RibD_C; cl17279
767434006841	Domain of unknown function (DUF336); Region: DUF336; pfam03928
767434006842	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
767434006843	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
767434006844	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434006845	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434006846	metal binding site [ion binding]; metal-binding site
767434006847	active site
767434006848	I-site; other site
767434006849	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
767434006850	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
767434006851	active site
767434006852	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
767434006853	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
767434006854	active site
767434006855	catalytic site [active]
767434006856	substrate binding site [chemical binding]; other site
767434006857	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
767434006858	RNA/DNA hybrid binding site [nucleotide binding]; other site
767434006859	active site
767434006860	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434006861	hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413
767434006862	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
767434006863	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
767434006864	N-acetyl-D-glucosamine binding site [chemical binding]; other site
767434006865	catalytic residue [active]
767434006866	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
767434006867	Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623
767434006868	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
767434006869	NAD binding site [chemical binding]; other site
767434006870	homotetramer interface [polypeptide binding]; other site
767434006871	homodimer interface [polypeptide binding]; other site
767434006872	substrate binding site [chemical binding]; other site
767434006873	active site
767434006874	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
767434006875	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
767434006876	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
767434006877	Predicted transcriptional regulators [Transcription]; Region: COG1733
767434006878	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
767434006879	dimerization interface [polypeptide binding]; other site
767434006880	putative DNA binding site [nucleotide binding]; other site
767434006881	putative Zn2+ binding site [ion binding]; other site
767434006882	Uncharacterized protein conserved in bacteria (DUF2058); Region: DUF2058; cl01201
767434006883	SlyX; Region: SlyX; pfam04102
767434006884	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
767434006885	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
767434006886	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
767434006887	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
767434006888	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
767434006889	NlpC/P60 family; Region: NLPC_P60; pfam00877
767434006890	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
767434006891	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
767434006892	catalytic residue [active]
767434006893	hypothetical protein; Provisional; Region: PRK07907
767434006894	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_5; cd05682
767434006895	metal binding site [ion binding]; metal-binding site
767434006896	putative dimer interface [polypeptide binding]; other site
767434006897	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
767434006898	SET domain; Region: SET; cl02566
767434006899	Peptidase M14-like domain; uncharacterized subgroup; Region: M14-like_1_4; cd06241
767434006900	putative active site [active]
767434006901	Zn binding site [ion binding]; other site
767434006902	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
767434006903	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
767434006904	active site
767434006905	Zn binding site [ion binding]; other site
767434006906	Tfp pilus assembly protein, ATPase PilU [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilU; COG5008
767434006907	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
767434006908	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
767434006909	Walker A motif; other site
767434006910	ATP binding site [chemical binding]; other site
767434006911	Walker B motif; other site
767434006912	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
767434006913	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
767434006914	Walker A motif; other site
767434006915	ATP binding site [chemical binding]; other site
767434006916	Walker B motif; other site
767434006917	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
767434006918	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
767434006919	YGGT family; Region: YGGT; pfam02325
767434006920	YGGT family; Region: YGGT; pfam02325
767434006921	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
767434006922	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
767434006923	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
767434006924	ribonuclease R; Region: RNase_R; TIGR02063
767434006925	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
767434006926	RNB domain; Region: RNB; pfam00773
767434006927	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
767434006928	RNA binding site [nucleotide binding]; other site
767434006929	Protein of unknown function (DUF1153); Region: DUF1153; pfam06627
767434006930	Integrase core domain; Region: rve; pfam00665
767434006931	Integrase core domain; Region: rve_3; pfam13683
767434006932	Protein of unknown function DUF262; Region: DUF262; pfam03235
767434006933	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
767434006934	active site
767434006935	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
767434006936	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
767434006937	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
767434006938	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
767434006939	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
767434006940	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557
767434006941	Protein of unknown function (DUF1249); Region: DUF1249; cl01223
767434006942	PEP synthetase regulatory protein; Provisional; Region: PRK05339
767434006943	phosphoenolpyruvate synthase; Validated; Region: PRK06464
767434006944	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
767434006945	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
767434006946	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
767434006947	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
767434006948	tetramerization interface [polypeptide binding]; other site
767434006949	active site
767434006950	Pantoate-beta-alanine ligase; Region: PanC; cd00560
767434006951	pantoate--beta-alanine ligase; Region: panC; TIGR00018
767434006952	active site
767434006953	ATP-binding site [chemical binding]; other site
767434006954	pantoate-binding site; other site
767434006955	HXXH motif; other site
767434006956	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
767434006957	active site
767434006958	oligomerization interface [polypeptide binding]; other site
767434006959	metal binding site [ion binding]; metal-binding site
767434006960	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
767434006961	catalytic center binding site [active]
767434006962	ATP binding site [chemical binding]; other site
767434006963	poly(A) polymerase; Region: pcnB; TIGR01942
767434006964	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
767434006965	active site
767434006966	NTP binding site [chemical binding]; other site
767434006967	metal binding triad [ion binding]; metal-binding site
767434006968	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
767434006969	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
767434006970	Ferredoxin [Energy production and conversion]; Region: COG1146
767434006971	4Fe-4S binding domain; Region: Fer4; cl02805
767434006972	Domain of unknown function (DUF3470); Region: DUF3470; pfam11953
767434006973	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
767434006974	dihydrodipicolinate synthase; Region: dapA; TIGR00674
767434006975	dimer interface [polypeptide binding]; other site
767434006976	active site
767434006977	catalytic residue [active]
767434006978	Glycine cleavage system regulatory protein [Amino acid transport and metabolism]; Region: GcvR; COG2716
767434006979	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
767434006980	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_2; cd04869
767434006981	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
767434006982	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
767434006983	catalytic triad [active]
767434006984	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
767434006985	PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883
767434006986	putative active site [active]
767434006987	PhoH-like protein; Region: PhoH; pfam02562
767434006988	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
767434006989	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
767434006990	tartrate dehydrogenase; Region: TTC; TIGR02089
767434006991	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
767434006992	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
767434006993	GSH binding site [chemical binding]; other site
767434006994	catalytic residues [active]
767434006995	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
767434006996	Peptidase family M48; Region: Peptidase_M48; cl12018
767434006997	phosphate regulon transcriptional regulatory protein PhoB; Region: PhoB; TIGR02154
767434006998	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434006999	active site
767434007000	phosphorylation site [posttranslational modification]
767434007001	intermolecular recognition site; other site
767434007002	dimerization interface [polypeptide binding]; other site
767434007003	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
767434007004	DNA binding site [nucleotide binding]
767434007005	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
767434007006	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434007007	dimer interface [polypeptide binding]; other site
767434007008	phosphorylation site [posttranslational modification]
767434007009	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434007010	ATP binding site [chemical binding]; other site
767434007011	Mg2+ binding site [ion binding]; other site
767434007012	G-X-G motif; other site
767434007013	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
767434007014	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
767434007015	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
767434007016	active site
767434007017	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
767434007018	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
767434007019	putative active site [active]
767434007020	putative metal binding site [ion binding]; other site
767434007021	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434007022	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434007023	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434007024	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434007025	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434007026	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434007027	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434007028	ribonuclease D; Region: rnd; TIGR01388
767434007029	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
767434007030	catalytic site [active]
767434007031	putative active site [active]
767434007032	putative substrate binding site [chemical binding]; other site
767434007033	HRDC domain; Region: HRDC; pfam00570
767434007034	AAA domain; Region: AAA_30; pfam13604
767434007035	Major royal jelly protein; Region: MRJP; pfam03022
767434007036	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
767434007037	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
767434007038	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
767434007039	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
767434007040	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
767434007041	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
767434007042	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
767434007043	active site
767434007044	catalytic tetrad [active]
767434007045	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
767434007046	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434007047	NAD(P) binding site [chemical binding]; other site
767434007048	active site
767434007049	Probable cobalt transporter subunit (CbtA); Region: CbtA; cl02266
767434007050	Broad specificity phosphatase PhoE and related phosphatases [General function prediction only]; Region: phoE; COG0406
767434007051	Domain of unknown function (DUF3315); Region: DUF3315; pfam11776
767434007052	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
767434007053	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
767434007054	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
767434007055	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
767434007056	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
767434007057	E3 interaction surface; other site
767434007058	lipoyl attachment site [posttranslational modification]; other site
767434007059	dihydrolipoamide acetyltransferase; Provisional; Region: PRK14843
767434007060	e3 binding domain; Region: E3_binding; pfam02817
767434007061	e3 binding domain; Region: E3_binding; pfam02817
767434007062	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
767434007063	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
767434007064	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
767434007065	alpha subunit interface [polypeptide binding]; other site
767434007066	TPP binding site [chemical binding]; other site
767434007067	heterodimer interface [polypeptide binding]; other site
767434007068	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
767434007069	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
767434007070	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
767434007071	tetramer interface [polypeptide binding]; other site
767434007072	TPP-binding site [chemical binding]; other site
767434007073	heterodimer interface [polypeptide binding]; other site
767434007074	phosphorylation loop region [posttranslational modification]
767434007075	ATP-dependent transcriptional regulator [Transcription]; Region: MalT; COG2909
767434007076	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
767434007077	DNA binding residues [nucleotide binding]
767434007078	dimerization interface [polypeptide binding]; other site
767434007079	ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones]; Region: CcmA; COG4133
767434007080	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434007081	Walker A/P-loop; other site
767434007082	ATP binding site [chemical binding]; other site
767434007083	Q-loop/lid; other site
767434007084	ABC transporter signature motif; other site
767434007085	Walker B; other site
767434007086	D-loop; other site
767434007087	H-loop/switch region; other site
767434007088	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
767434007089	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
767434007090	LysR family transcriptional regulator; Provisional; Region: PRK14997
767434007091	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434007092	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
767434007093	putative effector binding pocket; other site
767434007094	dimerization interface [polypeptide binding]; other site
767434007095	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
767434007096	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434007097	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
767434007098	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
767434007099	FMN binding site [chemical binding]; other site
767434007100	active site
767434007101	substrate binding site [chemical binding]; other site
767434007102	catalytic residue [active]
767434007103	Pirin-related protein [General function prediction only]; Region: COG1741
767434007104	Pirin; Region: Pirin; pfam02678
767434007105	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
767434007106	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
767434007107	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434007108	N-terminal plug; other site
767434007109	ligand-binding site [chemical binding]; other site
767434007110	integrase; Provisional; Region: PRK09692
767434007111	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
767434007112	active site
767434007113	Int/Topo IB signature motif; other site
767434007114	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
767434007115	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
767434007116	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
767434007117	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
767434007118	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
767434007119	active site
767434007120	HIGH motif; other site
767434007121	nucleotide binding site [chemical binding]; other site
767434007122	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
767434007123	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
767434007124	active site
767434007125	KMSKS motif; other site
767434007126	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
767434007127	tRNA binding surface [nucleotide binding]; other site
767434007128	anticodon binding site; other site
767434007129	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
767434007130	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
767434007131	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
767434007132	active site
767434007133	Riboflavin kinase; Region: Flavokinase; smart00904
767434007134	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
767434007135	MviN-like protein; Region: MVIN; pfam03023
767434007136	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
767434007137	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
767434007138	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
767434007139	FAD binding pocket [chemical binding]; other site
767434007140	FAD binding motif [chemical binding]; other site
767434007141	phosphate binding motif [ion binding]; other site
767434007142	NAD binding pocket [chemical binding]; other site
767434007143	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
767434007144	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
767434007145	catalytic residue [active]
767434007146	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
767434007147	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
767434007148	Siderophore biosynthesis protein domain; Region: AlcB; smart01006
767434007149	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
767434007150	IucA / IucC family; Region: IucA_IucC; pfam04183
767434007151	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
767434007152	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
767434007153	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434007154	N-terminal plug; other site
767434007155	ligand-binding site [chemical binding]; other site
767434007156	Obg family GTPase CgtA; Region: Obg_CgtA; TIGR02729
767434007157	GTP1/OBG; Region: GTP1_OBG; pfam01018
767434007158	Obg GTPase; Region: Obg; cd01898
767434007159	G1 box; other site
767434007160	GTP/Mg2+ binding site [chemical binding]; other site
767434007161	Switch I region; other site
767434007162	G2 box; other site
767434007163	G3 box; other site
767434007164	Switch II region; other site
767434007165	G4 box; other site
767434007166	G5 box; other site
767434007167	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
767434007168	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
767434007169	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
767434007170	Uncharacterized protein conserved in bacteria (DUF2059); Region: DUF2059; pfam09832
767434007171	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
767434007172	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
767434007173	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
767434007174	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
767434007175	pyruvate dehydrogenase; Provisional; Region: PRK09124
767434007176	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
767434007177	PYR/PP interface [polypeptide binding]; other site
767434007178	dimer interface [polypeptide binding]; other site
767434007179	tetramer interface [polypeptide binding]; other site
767434007180	TPP binding site [chemical binding]; other site
767434007181	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
767434007182	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
767434007183	TPP-binding site [chemical binding]; other site
767434007184	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
767434007185	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
767434007186	substrate binding pocket [chemical binding]; other site
767434007187	membrane-bound complex binding site; other site
767434007188	hinge residues; other site
767434007189	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
767434007190	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
767434007191	Walker A/P-loop; other site
767434007192	ATP binding site [chemical binding]; other site
767434007193	Q-loop/lid; other site
767434007194	ABC transporter signature motif; other site
767434007195	Walker B; other site
767434007196	D-loop; other site
767434007197	H-loop/switch region; other site
767434007198	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
767434007199	dimer interface [polypeptide binding]; other site
767434007200	conserved gate region; other site
767434007201	putative PBP binding loops; other site
767434007202	ABC-ATPase subunit interface; other site
767434007203	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
767434007204	dimer interface [polypeptide binding]; other site
767434007205	conserved gate region; other site
767434007206	putative PBP binding loops; other site
767434007207	ABC-ATPase subunit interface; other site
767434007208	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
767434007209	classical (c) SDRs; Region: SDR_c; cd05233
767434007210	NAD(P) binding site [chemical binding]; other site
767434007211	active site
767434007212	LamB/YcsF family of  lactam utilization protein; Region: LamB_YcsF_like; cd10787
767434007213	putative active site [active]
767434007214	Biotin carboxyl carrier protein [Lipid metabolism]; Region: AccB; COG0511
767434007215	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
767434007216	carboxyltransferase (CT) interaction site; other site
767434007217	biotinylation site [posttranslational modification]; other site
767434007218	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
767434007219	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
767434007220	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049
767434007221	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
767434007222	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434007223	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
767434007224	putative dimerization interface [polypeptide binding]; other site
767434007225	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434007226	putative substrate translocation pore; other site
767434007227	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434007228	aspartate aminotransferase; Provisional; Region: PRK06107
767434007229	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
767434007230	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434007231	homodimer interface [polypeptide binding]; other site
767434007232	catalytic residue [active]
767434007233	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434007234	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434007235	N-terminal plug; other site
767434007236	ligand-binding site [chemical binding]; other site
767434007237	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
767434007238	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434007239	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
767434007240	putative dimerization interface [polypeptide binding]; other site
767434007241	putative substrate binding pocket [chemical binding]; other site
767434007242	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
767434007243	acetolactate synthase; Reviewed; Region: PRK08617
767434007244	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
767434007245	PYR/PP interface [polypeptide binding]; other site
767434007246	dimer interface [polypeptide binding]; other site
767434007247	TPP binding site [chemical binding]; other site
767434007248	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
767434007249	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
767434007250	TPP-binding site [chemical binding]; other site
767434007251	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
767434007252	Cysteine-rich domain; Region: CCG; pfam02754
767434007253	Cysteine-rich domain; Region: CCG; pfam02754
767434007254	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
767434007255	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
767434007256	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
767434007257	hypothetical protein; Provisional; Region: PRK11667
767434007258	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434007259	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434007260	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
767434007261	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
767434007262	active site
767434007263	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
767434007264	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434007265	Major Facilitator Superfamily; Region: MFS_1; pfam07690
767434007266	putative substrate translocation pore; other site
767434007267	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
767434007268	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
767434007269	FAD binding pocket [chemical binding]; other site
767434007270	FAD binding motif [chemical binding]; other site
767434007271	phosphate binding motif [ion binding]; other site
767434007272	beta-alpha-beta structure motif; other site
767434007273	NAD binding pocket [chemical binding]; other site
767434007274	serine/threonine protein kinase; Provisional; Region: PRK12274
767434007275	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
767434007276	Protein of unknown function (DUF456); Region: DUF456; pfam04306
767434007277	Haemolysin-III related; Region: HlyIII; cl03831
767434007278	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
767434007279	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; pfam01062
767434007280	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
767434007281	active site clefts [active]
767434007282	zinc binding site [ion binding]; other site
767434007283	dimer interface [polypeptide binding]; other site
767434007284	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
767434007285	Putative catalytic domain, repeat 1, of Pseudomonas aeruginosa cardiolipin synthase and similar proteins; Region: PLDc_PaCLS_like_1; cd09155
767434007286	putative active site [active]
767434007287	catalytic site [active]
767434007288	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
767434007289	putative active site [active]
767434007290	catalytic site [active]
767434007291	major facilitator superfamily transporter; Provisional; Region: PRK05122
767434007292	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434007293	putative substrate translocation pore; other site
767434007294	Isochorismatase family; Region: Isochorismatase; pfam00857
767434007295	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
767434007296	catalytic triad [active]
767434007297	metal binding site [ion binding]; metal-binding site
767434007298	conserved cis-peptide bond; other site
767434007299	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
767434007300	DNA photolyase; Region: DNA_photolyase; pfam00875
767434007301	MASE2 domain; Region: MASE2; pfam05230
767434007302	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434007303	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434007304	metal binding site [ion binding]; metal-binding site
767434007305	active site
767434007306	I-site; other site
767434007307	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
767434007308	Cupin domain; Region: Cupin_2; pfam07883
767434007309	anthranilate synthase component I; Provisional; Region: PRK13565
767434007310	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
767434007311	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
767434007312	Domon-like ligand-binding domains; Region: DOMON_like; cl14783
767434007313	proteobacterial dedicated sortase system histidine kinase; Region: marine_sort_HK; TIGR03785
767434007314	putative ligand binding site [chemical binding]; other site
767434007315	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434007316	dimer interface [polypeptide binding]; other site
767434007317	phosphorylation site [posttranslational modification]
767434007318	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434007319	ATP binding site [chemical binding]; other site
767434007320	Mg2+ binding site [ion binding]; other site
767434007321	G-X-G motif; other site
767434007322	proteobacterial dedicated sortase system response regulator; Region: marine_sort_RR; TIGR03787
767434007323	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434007324	active site
767434007325	phosphorylation site [posttranslational modification]
767434007326	intermolecular recognition site; other site
767434007327	dimerization interface [polypeptide binding]; other site
767434007328	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
767434007329	DNA binding site [nucleotide binding]
767434007330	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
767434007331	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
767434007332	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
767434007333	substrate binding site [chemical binding]; other site
767434007334	hexamer interface [polypeptide binding]; other site
767434007335	metal binding site [ion binding]; metal-binding site
767434007336	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
767434007337	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
767434007338	putative metal binding site [ion binding]; other site
767434007339	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
767434007340	HSP70 interaction site [polypeptide binding]; other site
767434007341	Cytochrome c; Region: Cytochrom_C; cl11414
767434007342	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
767434007343	ATP binding site [chemical binding]; other site
767434007344	active site
767434007345	substrate binding site [chemical binding]; other site
767434007346	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
767434007347	Predicted membrane protein (DUF2061); Region: DUF2061; cl01257
767434007348	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434007349	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434007350	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434007351	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434007352	Tetratricopeptide repeat; Region: TPR_16; pfam13432
767434007353	TPR motif; other site
767434007354	binding surface
767434007355	Sulfotransferase domain; Region: Sulfotransfer_1; pfam00685
767434007356	cAMP phosphodiesterases class-II; Region: PDEase_II; cl17776
767434007357	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
767434007358	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
767434007359	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
767434007360	motif II; other site
767434007361	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
767434007362	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
767434007363	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
767434007364	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
767434007365	active site
767434007366	DNA polymerase IV; Validated; Region: PRK02406
767434007367	DNA binding site [nucleotide binding]
767434007368	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
767434007369	Zn2+ binding site [ion binding]; other site
767434007370	Mg2+ binding site [ion binding]; other site
767434007371	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
767434007372	E3 interaction surface; other site
767434007373	lipoyl attachment site [posttranslational modification]; other site
767434007374	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
767434007375	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
767434007376	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
767434007377	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
767434007378	E3 interaction surface; other site
767434007379	lipoyl attachment site [posttranslational modification]; other site
767434007380	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
767434007381	E3 interaction surface; other site
767434007382	lipoyl attachment site [posttranslational modification]; other site
767434007383	e3 binding domain; Region: E3_binding; pfam02817
767434007384	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11857
767434007385	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
767434007386	Mechanosensitive ion channel; Region: MS_channel; pfam00924
767434007387	Domain of unknown function (DUF2383); Region: DUF2383; cl17556
767434007388	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
767434007389	dinuclear metal binding motif [ion binding]; other site
767434007390	H+ Antiporter protein; Region: 2A0121; TIGR00900
767434007391	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
767434007392	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
767434007393	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
767434007394	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
767434007395	putative C-terminal domain interface [polypeptide binding]; other site
767434007396	putative GSH binding site (G-site) [chemical binding]; other site
767434007397	putative dimer interface [polypeptide binding]; other site
767434007398	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
767434007399	putative N-terminal domain interface [polypeptide binding]; other site
767434007400	putative dimer interface [polypeptide binding]; other site
767434007401	putative substrate binding pocket (H-site) [chemical binding]; other site
767434007402	Bacterial protein of unknown function (DUF883); Region: DUF883; cl01888
767434007403	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
767434007404	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
767434007405	dimer interface [polypeptide binding]; other site
767434007406	TPP-binding site [chemical binding]; other site
767434007407	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
767434007408	Malic enzyme, N-terminal domain; Region: malic; pfam00390
767434007409	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
767434007410	putative NAD(P) binding site [chemical binding]; other site
767434007411	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
767434007412	Predicted GTPases [General function prediction only]; Region: COG1162
767434007413	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
767434007414	RNA binding site [nucleotide binding]; other site
767434007415	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
767434007416	GTPase/Zn-binding domain interface [polypeptide binding]; other site
767434007417	GTP/Mg2+ binding site [chemical binding]; other site
767434007418	G4 box; other site
767434007419	G5 box; other site
767434007420	G1 box; other site
767434007421	Switch I region; other site
767434007422	G2 box; other site
767434007423	G3 box; other site
767434007424	Switch II region; other site
767434007425	aminotransferase AlaT; Validated; Region: PRK09265
767434007426	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
767434007427	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434007428	homodimer interface [polypeptide binding]; other site
767434007429	catalytic residue [active]
767434007430	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
767434007431	active site
767434007432	catalytic triad [active]
767434007433	oxyanion hole [active]
767434007434	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
767434007435	metal binding site [ion binding]; metal-binding site
767434007436	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
767434007437	putative GSH binding site [chemical binding]; other site
767434007438	catalytic residues [active]
767434007439	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
767434007440	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
767434007441	active site residue [active]
767434007442	tropinone reductase; Provisional; Region: PRK09242
767434007443	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434007444	NAD(P) binding site [chemical binding]; other site
767434007445	active site
767434007446	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
767434007447	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434007448	Walker A/P-loop; other site
767434007449	ATP binding site [chemical binding]; other site
767434007450	Q-loop/lid; other site
767434007451	ABC transporter signature motif; other site
767434007452	Walker B; other site
767434007453	D-loop; other site
767434007454	H-loop/switch region; other site
767434007455	signal peptide peptidase SppA, 67K type; Region: SppA_67K; TIGR00705
767434007456	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
767434007457	tandem repeat interface [polypeptide binding]; other site
767434007458	oligomer interface [polypeptide binding]; other site
767434007459	active site residues [active]
767434007460	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
767434007461	tandem repeat interface [polypeptide binding]; other site
767434007462	oligomer interface [polypeptide binding]; other site
767434007463	active site residues [active]
767434007464	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
767434007465	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434007466	active site
767434007467	phosphorylation site [posttranslational modification]
767434007468	intermolecular recognition site; other site
767434007469	dimerization interface [polypeptide binding]; other site
767434007470	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
767434007471	DNA binding site [nucleotide binding]
767434007472	sensor protein QseC; Provisional; Region: PRK10337
767434007473	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434007474	dimer interface [polypeptide binding]; other site
767434007475	phosphorylation site [posttranslational modification]
767434007476	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434007477	ATP binding site [chemical binding]; other site
767434007478	Mg2+ binding site [ion binding]; other site
767434007479	G-X-G motif; other site
767434007480	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
767434007481	G1 box; other site
767434007482	GTP/Mg2+ binding site [chemical binding]; other site
767434007483	Switch I region; other site
767434007484	G2 box; other site
767434007485	G3 box; other site
767434007486	Switch II region; other site
767434007487	G4 box; other site
767434007488	G5 box; other site
767434007489	Cytochrome c553 [Energy production and conversion]; Region: COG2863
767434007490	Cytochrome c; Region: Cytochrom_C; cl11414
767434007491	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
767434007492	catalytic residues [active]
767434007493	hinge region; other site
767434007494	alpha helical domain; other site
767434007495	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
767434007496	catalytic residues [active]
767434007497	hinge region; other site
767434007498	alpha helical domain; other site
767434007499	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
767434007500	putative catalytic site [active]
767434007501	putative metal binding site [ion binding]; other site
767434007502	putative phosphate binding site [ion binding]; other site
767434007503	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
767434007504	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
767434007505	N-acetyl-D-glucosamine binding site [chemical binding]; other site
767434007506	catalytic residue [active]
767434007507	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs; Region: NDUFA9_like_SDR_a; cd05271
767434007508	NADH(P)-binding; Region: NAD_binding_10; pfam13460
767434007509	putative NAD(P) binding site [chemical binding]; other site
767434007510	active site
767434007511	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
767434007512	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
767434007513	active site
767434007514	NTP binding site [chemical binding]; other site
767434007515	metal binding triad [ion binding]; metal-binding site
767434007516	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
767434007517	Sulfatase; Region: Sulfatase; pfam00884
767434007518	Uncharacterized conserved protein [Function unknown]; Region: COG1565
767434007519	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434007520	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434007521	pteridine reductase; Provisional; Region: PRK09135
767434007522	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434007523	NAD(P) binding site [chemical binding]; other site
767434007524	active site
767434007525	Predicted proteasome-type protease [Posttranslational modification, protein turnover, chaperones]; Region: COG3484
767434007526	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
767434007527	active site
767434007528	A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168
767434007529	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307
767434007530	Uncharacterized conserved protein [Function unknown]; Region: COG2308
767434007531	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
767434007532	catalytic center binding site [active]
767434007533	ATP binding site [chemical binding]; other site
767434007534	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
767434007535	Mechanosensitive ion channel; Region: MS_channel; pfam00924
767434007536	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
767434007537	homooctamer interface [polypeptide binding]; other site
767434007538	active site
767434007539	UGMP family protein; Validated; Region: PRK09604
767434007540	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
767434007541	Yqey-like protein; Region: YqeY; pfam09424
767434007542	Small integral membrane protein [Function unknown]; Region: COG5487; cl17674
767434007543	DNA primase; Validated; Region: dnaG; PRK05667
767434007544	CHC2 zinc finger; Region: zf-CHC2; pfam01807
767434007545	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
767434007546	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
767434007547	active site
767434007548	metal binding site [ion binding]; metal-binding site
767434007549	interdomain interaction site; other site
767434007550	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
767434007551	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
767434007552	Tfp pilus assembly protein PilP [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilP; COG3168
767434007553	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
767434007554	UbiA prenyltransferase family; Region: UbiA; pfam01040
767434007555	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
767434007556	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
767434007557	SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; Region: SURF1; cd06662
767434007558	Protein of unknown function (DUF2909); Region: DUF2909; pfam11137
767434007559	Cytochrome c oxidase subunit III.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_III; cd01665
767434007560	Subunit III/VIIa interface [polypeptide binding]; other site
767434007561	Phospholipid binding site [chemical binding]; other site
767434007562	Subunit I/III interface [polypeptide binding]; other site
767434007563	Subunit III/VIb interface [polypeptide binding]; other site
767434007564	Subunit III/VIa interface; other site
767434007565	Subunit III/Vb interface [polypeptide binding]; other site
767434007566	cytochrome c oxidase subunit I; Validated; Region: COX1; MTH00007
767434007567	Cytochrome C oxidase subunit I.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_I; cd01663
767434007568	Subunit I/III interface [polypeptide binding]; other site
767434007569	D-pathway; other site
767434007570	Subunit I/VIIc interface [polypeptide binding]; other site
767434007571	Subunit I/IV interface [polypeptide binding]; other site
767434007572	Subunit I/II interface [polypeptide binding]; other site
767434007573	Low-spin heme (heme a) binding site [chemical binding]; other site
767434007574	Subunit I/VIIa interface [polypeptide binding]; other site
767434007575	Subunit I/VIa interface [polypeptide binding]; other site
767434007576	Dimer interface; other site
767434007577	Putative water exit pathway; other site
767434007578	Binuclear center (heme a3/CuB) [ion binding]; other site
767434007579	K-pathway; other site
767434007580	Subunit I/Vb interface [polypeptide binding]; other site
767434007581	Putative proton exit pathway; other site
767434007582	Subunit I/VIb interface; other site
767434007583	Subunit I/VIc interface [polypeptide binding]; other site
767434007584	Electron transfer pathway; other site
767434007585	Subunit I/VIIIb interface [polypeptide binding]; other site
767434007586	Subunit I/VIIb interface [polypeptide binding]; other site
767434007587	Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790
767434007588	cytochrome c oxidase subunit II; Provisional; Region: COX2; MTH00051
767434007589	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
767434007590	Integral membrane protein (DUF2244); Region: DUF2244; pfam10003
767434007591	bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: PRK11904
767434007592	Proline dehydrogenase; Region: Pro_dh; pfam01619
767434007593	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
767434007594	Glutamate binding site [chemical binding]; other site
767434007595	NAD binding site [chemical binding]; other site
767434007596	catalytic residues [active]
767434007597	YcgL domain; Region: YcgL; cl01189
767434007598	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
767434007599	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
767434007600	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
767434007601	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
767434007602	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
767434007603	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
767434007604	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cl02529
767434007605	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
767434007606	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
767434007607	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
767434007608	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
767434007609	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
767434007610	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
767434007611	FOG: Ankyrin repeat [General function prediction only]; Region: Arp; COG0666
767434007612	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
767434007613	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
767434007614	putative active site [active]
767434007615	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
767434007616	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
767434007617	TrkA-N domain; Region: TrkA_N; pfam02254
767434007618	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
767434007619	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
767434007620	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952
767434007621	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
767434007622	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
767434007623	Surface antigen; Region: Bac_surface_Ag; pfam01103
767434007624	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
767434007625	Family of unknown function (DUF490); Region: DUF490; pfam04357
767434007626	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK04690
767434007627	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
767434007628	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
767434007629	bifunctional aspartate kinase/diaminopimelate decarboxylase protein; Provisional; Region: PRK08961
767434007630	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
767434007631	nucleotide binding site [chemical binding]; other site
767434007632	substrate binding site [chemical binding]; other site
767434007633	ACT domains of a bifunctional AKIII (LysC)-like aspartokinase/meso-diaminopimelate decarboxylase (DAPDC) bacterial protein; Region: ACT_AKiii-DAPDC_1; cd04935
767434007634	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
767434007635	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
767434007636	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
767434007637	catalytic residue [active]
767434007638	Oxygen tolerance; Region: BatD; pfam13584
767434007639	von Willebrand factor type A domain; Region: VWA_2; pfam13519
767434007640	metal ion-dependent adhesion site (MIDAS); other site
767434007641	TPR repeat; Region: TPR_11; pfam13414
767434007642	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434007643	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
767434007644	metal ion-dependent adhesion site (MIDAS); other site
767434007645	Domain of unknown function (DUF4381); Region: DUF4381; pfam14316
767434007646	Protein of unknown function DUF58; Region: DUF58; pfam01882
767434007647	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
767434007648	metal ion-dependent adhesion site (MIDAS); other site
767434007649	MoxR-like ATPases [General function prediction only]; Region: COG0714
767434007650	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434007651	Walker A motif; other site
767434007652	ATP binding site [chemical binding]; other site
767434007653	Walker B motif; other site
767434007654	arginine finger; other site
767434007655	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
767434007656	FtsX-like permease family; Region: FtsX; pfam02687
767434007657	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
767434007658	FtsX-like permease family; Region: FtsX; pfam02687
767434007659	Rhomboid family; Region: Rhomboid; cl11446
767434007660	type IV pilus secretin (or competence protein) PilQ; Region: IV_pilus_PilQ; TIGR02515
767434007661	Secretin and TonB N terminus short domain; Region: STN; smart00965
767434007662	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
767434007663	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
767434007664	Pilus assembly protein, PilP; Region: PilP; pfam04351
767434007665	Pilus assembly protein, PilO; Region: PilO; pfam04350
767434007666	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
767434007667	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
767434007668	Competence protein A; Region: Competence_A; pfam11104
767434007669	Cell division protein FtsA; Region: FtsA; pfam14450
767434007670	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
767434007671	Transglycosylase; Region: Transgly; pfam00912
767434007672	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
767434007673	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
767434007674	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
767434007675	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
767434007676	dimer interface [polypeptide binding]; other site
767434007677	active site
767434007678	citrylCoA binding site [chemical binding]; other site
767434007679	NADH binding [chemical binding]; other site
767434007680	cationic pore residues; other site
767434007681	oxalacetate/citrate binding site [chemical binding]; other site
767434007682	coenzyme A binding site [chemical binding]; other site
767434007683	catalytic triad [active]
767434007684	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
767434007685	nuc_hydro_CeIAG: Nucleoside hydrolases similar to the inosine-adenosine-guanosine-preferring nucleoside hydrolase from Caenorhabditis elegans.  Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base; Region: nuc_hydro_CeIAG; cd02649
767434007686	active site
767434007687	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
767434007688	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
767434007689	ssDNA binding site; other site
767434007690	generic binding surface II; other site
767434007691	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
767434007692	ATP binding site [chemical binding]; other site
767434007693	putative Mg++ binding site [ion binding]; other site
767434007694	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
767434007695	nucleotide binding region [chemical binding]; other site
767434007696	ATP-binding site [chemical binding]; other site
767434007697	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
767434007698	homotrimer interaction site [polypeptide binding]; other site
767434007699	putative active site [active]
767434007700	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
767434007701	Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379
767434007702	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
767434007703	A circularly permuted ATPgrasp; Region: CP_ATPgrasp_1; cl17448
767434007704	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307
767434007705	A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168
767434007706	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
767434007707	GAF domain; Region: GAF_3; pfam13492
767434007708	GAF domain; Region: GAF_2; pfam13185
767434007709	GAF domain; Region: GAF; pfam01590
767434007710	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434007711	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434007712	metal binding site [ion binding]; metal-binding site
767434007713	active site
767434007714	I-site; other site
767434007715	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
767434007716	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
767434007717	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
767434007718	dimerization interface [polypeptide binding]; other site
767434007719	domain crossover interface; other site
767434007720	redox-dependent activation switch; other site
767434007721	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
767434007722	Transglycosylase; Region: Transgly; cl17702
767434007723	dimerization interface [polypeptide binding]; other site
767434007724	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); Region: GlcNAc_2-epim; pfam07221
767434007725	putative active cleft [active]
767434007726	short chain dehydrogenase; Provisional; Region: PRK06701
767434007727	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434007728	NAD(P) binding site [chemical binding]; other site
767434007729	active site
767434007730	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
767434007731	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
767434007732	Ligand binding site; other site
767434007733	Putative Catalytic site; other site
767434007734	DXD motif; other site
767434007735	TLC ATP/ADP transporter; Region: TLC; cl03940
767434007736	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cl00010
767434007737	dimerization interface [polypeptide binding]; other site
767434007738	DNA binding site [nucleotide binding]
767434007739	corepressor binding sites; other site
767434007740	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
767434007741	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
767434007742	tetramer interface [polypeptide binding]; other site
767434007743	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434007744	catalytic residue [active]
767434007745	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
767434007746	lipoyl attachment site [posttranslational modification]; other site
767434007747	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
767434007748	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
767434007749	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
767434007750	Permease; Region: Permease; pfam02405
767434007751	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
767434007752	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434007753	Walker A/P-loop; other site
767434007754	ATP binding site [chemical binding]; other site
767434007755	Q-loop/lid; other site
767434007756	ABC transporter signature motif; other site
767434007757	Walker B; other site
767434007758	D-loop; other site
767434007759	H-loop/switch region; other site
767434007760	virulence factor Mce family protein; Region: Mtu_fam_mce; TIGR00996
767434007761	mce related protein; Region: MCE; pfam02470
767434007762	Protein of unknown function (DUF330); Region: DUF330; cl01135
767434007763	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
767434007764	hydroxyglutarate oxidase; Provisional; Region: PRK11728
767434007765	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
767434007766	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
767434007767	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
767434007768	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
767434007769	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
767434007770	Probable Catalytic site; other site
767434007771	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159
767434007772	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
767434007773	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
767434007774	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
767434007775	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
767434007776	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
767434007777	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
767434007778	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
767434007779	WavE lipopolysaccharide synthesis; Region: WavE; pfam07507
767434007780	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
767434007781	active site
767434007782	Aminoglycoside/hydroxyurea antibiotic resistance kinase; Region: APH_6_hur; cl17810
767434007783	capsule biosynthesis phosphatase; Region: EcbF-BcbF; TIGR01689
767434007784	WavE lipopolysaccharide synthesis; Region: WavE; pfam07507
767434007785	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
767434007786	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
767434007787	Walker A/P-loop; other site
767434007788	ATP binding site [chemical binding]; other site
767434007789	Q-loop/lid; other site
767434007790	ABC transporter signature motif; other site
767434007791	Walker B; other site
767434007792	D-loop; other site
767434007793	H-loop/switch region; other site
767434007794	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
767434007795	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
767434007796	polysaccharide export inner-membrane protein, BexC/CtrB/KpsE family; Region: BexC_CtrB_KpsE; TIGR01010
767434007797	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsS; COG3562
767434007798	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159
767434007799	short chain dehydrogenase; Provisional; Region: PRK07024
767434007800	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434007801	NAD(P) binding site [chemical binding]; other site
767434007802	active site
767434007803	Sulfatase; Region: Sulfatase; pfam00884
767434007804	Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321
767434007805	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
767434007806	active site
767434007807	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
767434007808	Dehydratase domain in polyketide synthase (PKS) enzymes; Region: PKS_DH; smart00826
767434007809	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434007810	enoyl reductase of polyketide synthase; Region: enoyl_red; cd05195
767434007811	Enoylreductase; Region: PKS_ER; smart00829
767434007812	NAD(P) binding site [chemical binding]; other site
767434007813	beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 2, complex (x); Region: KR_2_FAS_SDR_x; cd08955
767434007814	KR domain; Region: KR; pfam08659
767434007815	putative NADP binding site [chemical binding]; other site
767434007816	active site
767434007817	Phosphopantetheine attachment site; Region: PKS_PP; smart00823
767434007818	UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell envelope biogenesis, outer membrane]; Region: LpxC; cl00512
767434007819	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
767434007820	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
767434007821	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
767434007822	substrate-cofactor binding pocket; other site
767434007823	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434007824	catalytic residue [active]
767434007825	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
767434007826	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
767434007827	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
767434007828	Ligand binding site [chemical binding]; other site
767434007829	Electron transfer flavoprotein domain; Region: ETF; pfam01012
767434007830	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
767434007831	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
767434007832	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
767434007833	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
767434007834	cell division ATP-binding protein FtsE; Region: FtsE; TIGR02673
767434007835	Walker A/P-loop; other site
767434007836	ATP binding site [chemical binding]; other site
767434007837	Q-loop/lid; other site
767434007838	ABC transporter signature motif; other site
767434007839	Walker B; other site
767434007840	D-loop; other site
767434007841	H-loop/switch region; other site
767434007842	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
767434007843	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
767434007844	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
767434007845	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
767434007846	homodimer interface [polypeptide binding]; other site
767434007847	substrate-cofactor binding pocket; other site
767434007848	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434007849	catalytic residue [active]
767434007850	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
767434007851	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
767434007852	NAD binding site [chemical binding]; other site
767434007853	substrate binding site [chemical binding]; other site
767434007854	homodimer interface [polypeptide binding]; other site
767434007855	active site
767434007856	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
767434007857	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
767434007858	substrate binding site; other site
767434007859	tetramer interface; other site
767434007860	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
767434007861	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
767434007862	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
767434007863	NADP binding site [chemical binding]; other site
767434007864	active site
767434007865	putative substrate binding site [chemical binding]; other site
767434007866	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
767434007867	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
767434007868	Substrate binding site; other site
767434007869	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
767434007870	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
767434007871	non-specific DNA binding site [nucleotide binding]; other site
767434007872	salt bridge; other site
767434007873	sequence-specific DNA binding site [nucleotide binding]; other site
767434007874	hypothetical protein; Provisional; Region: PRK04233
767434007875	SEC-C motif; Region: SEC-C; pfam02810
767434007876	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
767434007877	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
767434007878	HlyD family secretion protein; Region: HlyD_3; pfam13437
767434007879	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
767434007880	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
767434007881	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434007882	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
767434007883	dimerization interface [polypeptide binding]; other site
767434007884	Domain of unknown function (DUF202); Region: DUF202; pfam02656
767434007885	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4529
767434007886	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
767434007887	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
767434007888	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
767434007889	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
767434007890	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
767434007891	dimer interface [polypeptide binding]; other site
767434007892	ssDNA binding site [nucleotide binding]; other site
767434007893	tetramer (dimer of dimers) interface [polypeptide binding]; other site
767434007894	RES domain; Region: RES; cl02411
767434007895	putative toxin-antitoxin system antitoxin component, TIGR02293 family; Region: TAS_TIGR02293
767434007896	Protein of unknown function (DUF2384); Region: DUF2384; pfam09722
767434007897	penicillin-binding protein 1C; Provisional; Region: PRK11240
767434007898	Transglycosylase; Region: Transgly; pfam00912
767434007899	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
767434007900	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
767434007901	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
767434007902	MG2 domain; Region: A2M_N; pfam01835
767434007903	Alpha-2-macroglobulin family; Region: A2M; pfam00207
767434007904	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
767434007905	surface patch; other site
767434007906	thioester region; other site
767434007907	specificity defining residues; other site
767434007908	Domain of unknown function (DUF333); Region: DUF333; pfam03891
767434007909	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
767434007910	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
767434007911	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
767434007912	active site
767434007913	substrate binding site [chemical binding]; other site
767434007914	metal binding site [ion binding]; metal-binding site
767434007915	CopC domain; Region: CopC; pfam04234
767434007916	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434007917	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434007918	metal binding site [ion binding]; metal-binding site
767434007919	active site
767434007920	I-site; other site
767434007921	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
767434007922	Ligand Binding Site [chemical binding]; other site
767434007923	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE, gammaproteobacterial type; Region: rSAM_QueE_gams; TIGR04349
767434007924	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
767434007925	FeS/SAM binding site; other site
767434007926	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
767434007927	Tetratricopeptide repeat; Region: TPR_6; pfam13174
767434007928	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
767434007929	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
767434007930	ligand binding site [chemical binding]; other site
767434007931	translocation protein TolB; Provisional; Region: tolB; PRK04922
767434007932	TolB amino-terminal domain; Region: TolB_N; pfam04052
767434007933	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
767434007934	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
767434007935	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
767434007936	TolA protein; Region: tolA_full; TIGR02794
767434007937	TonB C terminal; Region: TonB_2; pfam13103
767434007938	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
767434007939	TolR protein; Region: tolR; TIGR02801
767434007940	TolQ protein; Region: tolQ; TIGR02796
767434007941	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
767434007942	active site
767434007943	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
767434007944	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434007945	Walker A motif; other site
767434007946	ATP binding site [chemical binding]; other site
767434007947	Walker B motif; other site
767434007948	arginine finger; other site
767434007949	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
767434007950	K+ transporter [Inorganic ion transport and metabolism]; Region: Kup; COG3158
767434007951	potassium uptake protein; Region: kup; TIGR00794
767434007952	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
767434007953	RuvA N terminal domain; Region: RuvA_N; pfam01330
767434007954	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
767434007955	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
767434007956	active site
767434007957	putative DNA-binding cleft [nucleotide binding]; other site
767434007958	dimer interface [polypeptide binding]; other site
767434007959	hypothetical protein; Validated; Region: PRK00110
767434007960	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
767434007961	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
767434007962	nucleophilic elbow; other site
767434007963	catalytic triad; other site
767434007964	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
767434007965	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
767434007966	dimer interface [polypeptide binding]; other site
767434007967	anticodon binding site; other site
767434007968	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
767434007969	homodimer interface [polypeptide binding]; other site
767434007970	motif 1; other site
767434007971	active site
767434007972	motif 2; other site
767434007973	GAD domain; Region: GAD; pfam02938
767434007974	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
767434007975	active site
767434007976	motif 3; other site
767434007977	putative regulatory protein, FmdB family; Region: CxxC_CxxC_SSSS; TIGR02605
767434007978	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434007979	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434007980	N-terminal plug; other site
767434007981	ligand-binding site [chemical binding]; other site
767434007982	putative aminotransferase; Provisional; Region: PRK09105
767434007983	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
767434007984	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434007985	homodimer interface [polypeptide binding]; other site
767434007986	catalytic residue [active]
767434007987	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
767434007988	Clp amino terminal domain; Region: Clp_N; pfam02861
767434007989	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434007990	Walker A motif; other site
767434007991	ATP binding site [chemical binding]; other site
767434007992	Walker B motif; other site
767434007993	arginine finger; other site
767434007994	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434007995	Walker A motif; other site
767434007996	ATP binding site [chemical binding]; other site
767434007997	Walker B motif; other site
767434007998	arginine finger; other site
767434007999	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
767434008000	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
767434008001	Trehalose-phosphatase; Region: Trehalose_PPase; pfam02358
767434008002	active site
767434008003	motif I; other site
767434008004	motif II; other site
767434008005	Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387
767434008006	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
767434008007	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
767434008008	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
767434008009	active site
767434008010	homotetramer interface [polypeptide binding]; other site
767434008011	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
767434008012	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650
767434008013	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
767434008014	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
767434008015	RNA binding surface [nucleotide binding]; other site
767434008016	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
767434008017	active site
767434008018	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
767434008019	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
767434008020	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434008021	NAD(P) binding site [chemical binding]; other site
767434008022	active site
767434008023	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434008024	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434008025	NAD synthetase; Provisional; Region: PRK13981
767434008026	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
767434008027	multimer interface [polypeptide binding]; other site
767434008028	active site
767434008029	catalytic triad [active]
767434008030	protein interface 1 [polypeptide binding]; other site
767434008031	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
767434008032	homodimer interface [polypeptide binding]; other site
767434008033	NAD binding pocket [chemical binding]; other site
767434008034	ATP binding pocket [chemical binding]; other site
767434008035	Mg binding site [ion binding]; other site
767434008036	active-site loop [active]
767434008037	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434008038	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434008039	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
767434008040	putative effector binding pocket; other site
767434008041	dimerization interface [polypeptide binding]; other site
767434008042	Cupin domain; Region: Cupin_2; cl17218
767434008043	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
767434008044	CoA binding domain; Region: CoA_binding; smart00881
767434008045	CoA-ligase; Region: Ligase_CoA; pfam00549
767434008046	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
767434008047	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
767434008048	CoA-ligase; Region: Ligase_CoA; pfam00549
767434008049	Response regulator receiver domain; Region: Response_reg; pfam00072
767434008050	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434008051	active site
767434008052	phosphorylation site [posttranslational modification]
767434008053	intermolecular recognition site; other site
767434008054	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434008055	dimer interface [polypeptide binding]; other site
767434008056	phosphorylation site [posttranslational modification]
767434008057	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434008058	ATP binding site [chemical binding]; other site
767434008059	Mg2+ binding site [ion binding]; other site
767434008060	G-X-G motif; other site
767434008061	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
767434008062	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434008063	active site
767434008064	phosphorylation site [posttranslational modification]
767434008065	intermolecular recognition site; other site
767434008066	dimerization interface [polypeptide binding]; other site
767434008067	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
767434008068	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
767434008069	putative active site [active]
767434008070	heme pocket [chemical binding]; other site
767434008071	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434008072	dimer interface [polypeptide binding]; other site
767434008073	phosphorylation site [posttranslational modification]
767434008074	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434008075	ATP binding site [chemical binding]; other site
767434008076	Mg2+ binding site [ion binding]; other site
767434008077	G-X-G motif; other site
767434008078	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
767434008079	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434008080	putative substrate translocation pore; other site
767434008081	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
767434008082	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
767434008083	putative substrate binding site [chemical binding]; other site
767434008084	putative ATP binding site [chemical binding]; other site
767434008085	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
767434008086	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
767434008087	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
767434008088	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
767434008089	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
767434008090	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
767434008091	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
767434008092	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
767434008093	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434008094	NADH(P)-binding; Region: NAD_binding_10; pfam13460
767434008095	NAD(P) binding site [chemical binding]; other site
767434008096	active site
767434008097	shikimate kinase; Reviewed; Region: aroK; PRK00131
767434008098	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
767434008099	ADP binding site [chemical binding]; other site
767434008100	magnesium binding site [ion binding]; other site
767434008101	putative shikimate binding site; other site
767434008102	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
767434008103	active site
767434008104	dimer interface [polypeptide binding]; other site
767434008105	metal binding site [ion binding]; metal-binding site
767434008106	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
767434008107	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
767434008108	substrate binding site [chemical binding]; other site
767434008109	active site
767434008110	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
767434008111	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
767434008112	active site
767434008113	HIGH motif; other site
767434008114	nucleotide binding site [chemical binding]; other site
767434008115	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
767434008116	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
767434008117	active site
767434008118	KMSKS motif; other site
767434008119	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
767434008120	tRNA binding surface [nucleotide binding]; other site
767434008121	anticodon binding site; other site
767434008122	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
767434008123	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
767434008124	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
767434008125	metal binding triad; other site
767434008126	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
767434008127	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
767434008128	metal binding triad; other site
767434008129	sulfite reductase [NADPH] flavoprotein, alpha-component; Region: cysJ; TIGR01931
767434008130	Flavodoxin; Region: Flavodoxin_1; pfam00258
767434008131	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
767434008132	FAD binding pocket [chemical binding]; other site
767434008133	FAD binding motif [chemical binding]; other site
767434008134	catalytic residues [active]
767434008135	NAD binding pocket [chemical binding]; other site
767434008136	phosphate binding motif [ion binding]; other site
767434008137	beta-alpha-beta structure motif; other site
767434008138	sulfite reductase subunit beta; Provisional; Region: PRK13504
767434008139	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
767434008140	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
767434008141	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
767434008142	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
767434008143	Active Sites [active]
767434008144	bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Validated; Region: PRK05537
767434008145	ATP-sulfurylase; Region: ATPS; cd00517
767434008146	active site
767434008147	HXXH motif; other site
767434008148	flexible loop; other site
767434008149	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
767434008150	ligand-binding site [chemical binding]; other site
767434008151	transcriptional regulator CysB-like protein; Reviewed; Region: PRK12680
767434008152	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434008153	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
767434008154	dimerization interface [polypeptide binding]; other site
767434008155	siroheme synthase; Provisional; Region: cysG; PRK10637
767434008156	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
767434008157	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
767434008158	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
767434008159	active site
767434008160	SAM binding site [chemical binding]; other site
767434008161	homodimer interface [polypeptide binding]; other site
767434008162	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434008163	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434008164	sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022
767434008165	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
767434008166	active site
767434008167	sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022
767434008168	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
767434008169	active site
767434008170	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
767434008171	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
767434008172	active site
767434008173	non-prolyl cis peptide bond; other site
767434008174	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
767434008175	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
767434008176	ring oligomerisation interface [polypeptide binding]; other site
767434008177	ATP/Mg binding site [chemical binding]; other site
767434008178	stacking interactions; other site
767434008179	hinge regions; other site
767434008180	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
767434008181	oligomerisation interface [polypeptide binding]; other site
767434008182	mobile loop; other site
767434008183	roof hairpin; other site
767434008184	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
767434008185	Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4232
767434008186	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
767434008187	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
767434008188	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
767434008189	DsbD alpha interface [polypeptide binding]; other site
767434008190	catalytic residues [active]
767434008191	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
767434008192	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
767434008193	catalytic residues [active]
767434008194	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
767434008195	Dehydroquinase class II; Region: DHquinase_II; pfam01220
767434008196	active site
767434008197	trimer interface [polypeptide binding]; other site
767434008198	dimer interface [polypeptide binding]; other site
767434008199	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
767434008200	carboxyltransferase (CT) interaction site; other site
767434008201	biotinylation site [posttranslational modification]; other site
767434008202	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
767434008203	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
767434008204	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
767434008205	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
767434008206	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
767434008207	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
767434008208	Protein of unknown function (DUF3426); Region: DUF3426; pfam11906
767434008209	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
767434008210	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
767434008211	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
767434008212	purine monophosphate binding site [chemical binding]; other site
767434008213	dimer interface [polypeptide binding]; other site
767434008214	putative catalytic residues [active]
767434008215	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
767434008216	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
767434008217	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
767434008218	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
767434008219	polyol permease family; Region: 2A0118; TIGR00897
767434008220	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434008221	putative substrate translocation pore; other site
767434008222	Predicted membrane protein [Function unknown]; Region: COG2510
767434008223	Protein of unknown function (DUF2782); Region: DUF2782; pfam11191
767434008224	DNA polymerase I; Provisional; Region: PRK05755
767434008225	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
767434008226	active site
767434008227	metal binding site 1 [ion binding]; metal-binding site
767434008228	putative 5' ssDNA interaction site; other site
767434008229	metal binding site 3; metal-binding site
767434008230	metal binding site 2 [ion binding]; metal-binding site
767434008231	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
767434008232	putative DNA binding site [nucleotide binding]; other site
767434008233	putative metal binding site [ion binding]; other site
767434008234	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
767434008235	active site
767434008236	catalytic site [active]
767434008237	substrate binding site [chemical binding]; other site
767434008238	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
767434008239	active site
767434008240	DNA binding site [nucleotide binding]
767434008241	catalytic site [active]
767434008242	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
767434008243	Part of AAA domain; Region: AAA_19; pfam13245
767434008244	Family description; Region: UvrD_C_2; pfam13538
767434008245	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
767434008246	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
767434008247	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434008248	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
767434008249	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434008250	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434008251	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
767434008252	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
767434008253	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
767434008254	TPR motif; other site
767434008255	TPR repeat; Region: TPR_11; pfam13414
767434008256	binding surface
767434008257	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
767434008258	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
767434008259	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
767434008260	active site
767434008261	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; cl17557
767434008262	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
767434008263	active site residue [active]
767434008264	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
767434008265	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434008266	active site
767434008267	phosphorylation site [posttranslational modification]
767434008268	intermolecular recognition site; other site
767434008269	dimerization interface [polypeptide binding]; other site
767434008270	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
767434008271	DNA binding site [nucleotide binding]
767434008272	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
767434008273	dimerization interface [polypeptide binding]; other site
767434008274	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
767434008275	dimer interface [polypeptide binding]; other site
767434008276	phosphorylation site [posttranslational modification]
767434008277	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434008278	ATP binding site [chemical binding]; other site
767434008279	Mg2+ binding site [ion binding]; other site
767434008280	G-X-G motif; other site
767434008281	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
767434008282	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
767434008283	sequence-specific DNA binding site [nucleotide binding]; other site
767434008284	salt bridge; other site
767434008285	Predicted flavoprotein [General function prediction only]; Region: COG0431
767434008286	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
767434008287	aminotransferase; Validated; Region: PRK08175
767434008288	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
767434008289	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434008290	homodimer interface [polypeptide binding]; other site
767434008291	catalytic residue [active]
767434008292	RmuC family; Region: RmuC; pfam02646
767434008293	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
767434008294	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434008295	putative substrate translocation pore; other site
767434008296	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434008297	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
767434008298	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
767434008299	active site
767434008300	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
767434008301	active site
767434008302	P-loop; other site
767434008303	phosphorylation site [posttranslational modification]
767434008304	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
767434008305	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
767434008306	active site
767434008307	P-loop; other site
767434008308	phosphorylation site [posttranslational modification]
767434008309	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; cl17425
767434008310	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
767434008311	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
767434008312	putative substrate binding site [chemical binding]; other site
767434008313	putative ATP binding site [chemical binding]; other site
767434008314	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
767434008315	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
767434008316	active site
767434008317	phosphorylation site [posttranslational modification]
767434008318	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
767434008319	dimerization domain swap beta strand [polypeptide binding]; other site
767434008320	regulatory protein interface [polypeptide binding]; other site
767434008321	active site
767434008322	regulatory phosphorylation site [posttranslational modification]; other site
767434008323	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
767434008324	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
767434008325	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
767434008326	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
767434008327	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
767434008328	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
767434008329	DNA binding site [nucleotide binding]
767434008330	domain linker motif; other site
767434008331	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
767434008332	Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377
767434008333	peptidase domain interface [polypeptide binding]; other site
767434008334	Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056
767434008335	active site
767434008336	catalytic triad [active]
767434008337	calcium binding site [ion binding]; other site
767434008338	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
767434008339	GTP cyclohydrolase I; Provisional; Region: PLN03044
767434008340	active site
767434008341	P-loop containing region of AAA domain; Region: AAA_29; cl17516
767434008342	AAA domain; Region: AAA_21; pfam13304
767434008343	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434008344	ABC transporter signature motif; other site
767434008345	Walker B; other site
767434008346	D-loop; other site
767434008347	H-loop/switch region; other site
767434008348	Domain of unknown function (DUF1993); Region: DUF1993; pfam09351
767434008349	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
767434008350	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
767434008351	dimer interface [polypeptide binding]; other site
767434008352	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434008353	catalytic residue [active]
767434008354	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
767434008355	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
767434008356	DEAD_2; Region: DEAD_2; pfam06733
767434008357	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
767434008358	Peptidase family M1; Region: Peptidase_M1; pfam01433
767434008359	Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); Region: M1_APN_2; cd09601
767434008360	Zn binding site [ion binding]; other site
767434008361	Domain of unknown function (DUF3358); Region: DUF3358; pfam11838
767434008362	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434008363	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434008364	metal binding site [ion binding]; metal-binding site
767434008365	active site
767434008366	I-site; other site
767434008367	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
767434008368	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
767434008369	heme-binding site [chemical binding]; other site
767434008370	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
767434008371	FAD binding pocket [chemical binding]; other site
767434008372	FAD binding motif [chemical binding]; other site
767434008373	phosphate binding motif [ion binding]; other site
767434008374	beta-alpha-beta structure motif; other site
767434008375	NAD binding pocket [chemical binding]; other site
767434008376	Heme binding  pocket [chemical binding]; other site
767434008377	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
767434008378	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434008379	Walker A motif; other site
767434008380	ATP binding site [chemical binding]; other site
767434008381	Walker B motif; other site
767434008382	arginine finger; other site
767434008383	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
767434008384	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
767434008385	Dopa 4,5-dioxygenase family; Region: DOPA_dioxygen; pfam08883
767434008386	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01096
767434008387	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
767434008388	Zn2+ binding site [ion binding]; other site
767434008389	Mg2+ binding site [ion binding]; other site
767434008390	HipA N-terminal domain; Region: Couple_hipA; pfam13657
767434008391	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
767434008392	HipA-like N-terminal domain; Region: HipA_N; pfam07805
767434008393	HipA-like C-terminal domain; Region: HipA_C; pfam07804
767434008394	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
767434008395	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
767434008396	non-specific DNA binding site [nucleotide binding]; other site
767434008397	salt bridge; other site
767434008398	sequence-specific DNA binding site [nucleotide binding]; other site
767434008399	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
767434008400	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
767434008401	glutaminase active site [active]
767434008402	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
767434008403	dimer interface [polypeptide binding]; other site
767434008404	active site
767434008405	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
767434008406	dimer interface [polypeptide binding]; other site
767434008407	active site
767434008408	cystathionine beta-synthase; Region: cysta_beta; TIGR01137
767434008409	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
767434008410	dimer interface [polypeptide binding]; other site
767434008411	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434008412	catalytic residue [active]
767434008413	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream.   The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; Region: CBS_pair_PALP_assoc2; cd04609
767434008414	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
767434008415	Phosphoglycerate kinase; Region: PGK; pfam00162
767434008416	substrate binding site [chemical binding]; other site
767434008417	hinge regions; other site
767434008418	ADP binding site [chemical binding]; other site
767434008419	catalytic site [active]
767434008420	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
767434008421	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
767434008422	substrate binding pocket [chemical binding]; other site
767434008423	chain length determination region; other site
767434008424	substrate-Mg2+ binding site; other site
767434008425	catalytic residues [active]
767434008426	aspartate-rich region 1; other site
767434008427	active site lid residues [active]
767434008428	aspartate-rich region 2; other site
767434008429	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434008430	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434008431	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434008432	N-terminal plug; other site
767434008433	ligand-binding site [chemical binding]; other site
767434008434	Uncharacterized protein involved in tolerance to divalent cations [Inorganic ion transport and metabolism]; Region: CutA; COG1324
767434008435	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
767434008436	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
767434008437	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
767434008438	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
767434008439	active site
767434008440	dimer interface [polypeptide binding]; other site
767434008441	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
767434008442	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
767434008443	active site
767434008444	FMN binding site [chemical binding]; other site
767434008445	substrate binding site [chemical binding]; other site
767434008446	3Fe-4S cluster binding site [ion binding]; other site
767434008447	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
767434008448	domain interface; other site
767434008449	Peptidase family M23; Region: Peptidase_M23; pfam01551
767434008450	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
767434008451	C-terminal peptidase (prc); Region: prc; TIGR00225
767434008452	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
767434008453	protein binding site [polypeptide binding]; other site
767434008454	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
767434008455	Catalytic dyad [active]
767434008456	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
767434008457	Sec-independent protein translocase protein (TatC); Region: TatC; cl00521
767434008458	Sec-independent protein secretion pathway components [Intracellular trafficking and secretion]; Region: TatA; COG1826
767434008459	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
767434008460	The SYLF domain (also called DUF500), a novel lipid-binding module; Region: SYLF; cd11524
767434008461	putative amphipathic alpha helix; other site
767434008462	ferrochelatase; Reviewed; Region: hemH; PRK00035
767434008463	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
767434008464	C-terminal domain interface [polypeptide binding]; other site
767434008465	active site
767434008466	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
767434008467	active site
767434008468	N-terminal domain interface [polypeptide binding]; other site
767434008469	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
767434008470	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
767434008471	PapC N-terminal domain; Region: PapC_N; pfam13954
767434008472	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
767434008473	PapC C-terminal domain; Region: PapC_C; pfam13953
767434008474	putative chaperone protein EcpD; Provisional; Region: PRK09926
767434008475	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
767434008476	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
767434008477	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
767434008478	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
767434008479	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
767434008480	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
767434008481	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434008482	Walker A/P-loop; other site
767434008483	ATP binding site [chemical binding]; other site
767434008484	Q-loop/lid; other site
767434008485	ABC transporter signature motif; other site
767434008486	Walker B; other site
767434008487	D-loop; other site
767434008488	H-loop/switch region; other site
767434008489	TAP-like protein; Region: Abhydrolase_4; pfam08386
767434008490	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
767434008491	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
767434008492	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434008493	Walker A/P-loop; other site
767434008494	ATP binding site [chemical binding]; other site
767434008495	Q-loop/lid; other site
767434008496	ABC transporter signature motif; other site
767434008497	Walker B; other site
767434008498	D-loop; other site
767434008499	H-loop/switch region; other site
767434008500	inner membrane transport permease; Provisional; Region: PRK15066
767434008501	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
767434008502	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
767434008503	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
767434008504	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
767434008505	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
767434008506	ATP binding site [chemical binding]; other site
767434008507	Mg++ binding site [ion binding]; other site
767434008508	motif III; other site
767434008509	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
767434008510	nucleotide binding region [chemical binding]; other site
767434008511	ATP-binding site [chemical binding]; other site
767434008512	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
767434008513	putative RNA binding site [nucleotide binding]; other site
767434008514	Glutamine cyclotransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG3823
767434008515	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
767434008516	Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939
767434008517	Serine carboxypeptidase; Region: Peptidase_S10; cl08270
767434008518	Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939
767434008519	Serine carboxypeptidase; Region: Peptidase_S10; cl08270
767434008520	Phospholipase C [Cell envelope biogenesis, outer membrane]; Region: PlcC; COG3511
767434008521	acid phosphatase, Burkholderia-type; Region: acid_phos_Burk; TIGR03397
767434008522	leukotriene A-4 hydrolase/aminopeptidase; Region: leuko_A4_hydro; TIGR02411
767434008523	Peptidase M1 family contains leukotriene A4 hydrolase; Region: M1_LTA4H; cd09599
767434008524	active site
767434008525	Zn binding site [ion binding]; other site
767434008526	Leukotriene A4 hydrolase, C-terminal; Region: Leuk-A4-hydro_C; pfam09127
767434008527	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
767434008528	Flagellar regulator YcgR; Region: YcgR; pfam07317
767434008529	PilZ domain; Region: PilZ; pfam07238
767434008530	Protein of unknown function DUF45; Region: DUF45; pfam01863
767434008531	Putative exonuclease, RdgC; Region: RdgC; pfam04381
767434008532	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
767434008533	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
767434008534	REG-2-like, HAD superfamily (subfamily IA) hydrolase; Region: DREG-2; TIGR02252
767434008535	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
767434008536	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
767434008537	OHCU decarboxylase; Region: OHCU_decarbox; pfam09349
767434008538	putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212
767434008539	Catalytic domain of bacterial PuuE allantoinases, Schizosaccharomyces pombe chitin deacetylase 1 (SpCDA1), and similar proteins; Region: CE4_PuuE_SpCDA1; cd10977
767434008540	active site
767434008541	catalytic site [active]
767434008542	tetramer interface [polypeptide binding]; other site
767434008543	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
767434008544	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
767434008545	iron-sulfur cluster [ion binding]; other site
767434008546	[2Fe-2S] cluster binding site [ion binding]; other site
767434008547	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
767434008548	hydrophobic ligand binding site; other site
767434008549	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
767434008550	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
767434008551	xanthine permease; Region: pbuX; TIGR03173
767434008552	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
767434008553	active site
767434008554	homotetramer interface [polypeptide binding]; other site
767434008555	Predicted membrane protein [Function unknown]; Region: COG3748
767434008556	Protein of unknown function (DUF989); Region: DUF989; pfam06181
767434008557	Cytochrome c; Region: Cytochrom_C; pfam00034
767434008558	allantoicase; Provisional; Region: PRK13257
767434008559	Allantoicase repeat; Region: Allantoicase; pfam03561
767434008560	Allantoicase repeat; Region: Allantoicase; pfam03561
767434008561	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
767434008562	ureidoglycolate hydrolase; Provisional; Region: PRK03606
767434008563	Carbohydrate-selective porin, OprB family; Region: OprB; cl17816
767434008564	Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318
767434008565	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434008566	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
767434008567	Cytochrome c; Region: Cytochrom_C; pfam00034
767434008568	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
767434008569	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
767434008570	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
767434008571	Pathogenicity locus; Region: Cdd1; pfam11731
767434008572	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434008573	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434008574	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
767434008575	dimerization interface [polypeptide binding]; other site
767434008576	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
767434008577	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434008578	NAD(P) binding site [chemical binding]; other site
767434008579	active site
767434008580	TonB-dependent copper receptor; Region: TonB-copper; TIGR01778
767434008581	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434008582	N-terminal plug; other site
767434008583	ligand-binding site [chemical binding]; other site
767434008584	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434008585	AAA domain; Region: AAA_21; pfam13304
767434008586	Walker A/P-loop; other site
767434008587	ATP binding site [chemical binding]; other site
767434008588	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
767434008589	KilA-N domain; Region: KilA-N; pfam04383
767434008590	Helix-turn-helix domain; Region: HTH_39; pfam14090
767434008591	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
767434008592	Toprim domain; Region: Toprim_3; pfam13362
767434008593	active site
767434008594	metal binding site [ion binding]; metal-binding site
767434008595	Domain of unknown function (DUF927); Region: DUF927; pfam06048
767434008596	integrase; Provisional; Region: PRK09692
767434008597	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
767434008598	active site
767434008599	Int/Topo IB signature motif; other site
767434008600	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
767434008601	putative active site [active]
767434008602	Ap4A binding site [chemical binding]; other site
767434008603	nudix motif; other site
767434008604	putative metal binding site [ion binding]; other site
767434008605	Bacterioferritin-associated ferredoxin [Inorganic ion transport and metabolism]; Region: Bfd; COG2906
767434008606	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
767434008607	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
767434008608	heme binding site [chemical binding]; other site
767434008609	ferroxidase pore; other site
767434008610	ferroxidase diiron center [ion binding]; other site
767434008611	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
767434008612	NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding [DNA replication, recombination, and repair]; Region: NPY1; COG2816
767434008613	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
767434008614	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
767434008615	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
767434008616	putative NADH binding site [chemical binding]; other site
767434008617	putative active site [active]
767434008618	nudix motif; other site
767434008619	putative metal binding site [ion binding]; other site
767434008620	CobD/Cbib protein; Region: CobD_Cbib; cl00561
767434008621	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
767434008622	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
767434008623	active site
767434008624	catalytic tetrad [active]
767434008625	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
767434008626	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
767434008627	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
767434008628	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
767434008629	H-NS histone family; Region: Histone_HNS; pfam00816
767434008630	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
767434008631	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
767434008632	acyl-activating enzyme (AAE) consensus motif; other site
767434008633	Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365
767434008634	AMP binding site [chemical binding]; other site
767434008635	active site
767434008636	CoA binding site [chemical binding]; other site
767434008637	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
767434008638	DNA topoisomerase I; Provisional; Region: PRK08780
767434008639	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
767434008640	active site
767434008641	interdomain interaction site; other site
767434008642	putative metal-binding site [ion binding]; other site
767434008643	nucleotide binding site [chemical binding]; other site
767434008644	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
767434008645	domain I; other site
767434008646	DNA binding groove [nucleotide binding]
767434008647	phosphate binding site [ion binding]; other site
767434008648	domain II; other site
767434008649	domain III; other site
767434008650	nucleotide binding site [chemical binding]; other site
767434008651	catalytic site [active]
767434008652	domain IV; other site
767434008653	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
767434008654	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
767434008655	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
767434008656	DNA protecting protein DprA; Region: dprA; TIGR00732
767434008657	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
767434008658	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
767434008659	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
767434008660	active site
767434008661	catalytic residues [active]
767434008662	metal binding site [ion binding]; metal-binding site
767434008663	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
767434008664	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
767434008665	putative active site [active]
767434008666	substrate binding site [chemical binding]; other site
767434008667	putative cosubstrate binding site; other site
767434008668	catalytic site [active]
767434008669	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
767434008670	substrate binding site [chemical binding]; other site
767434008671	16S rRNA methyltransferase B; Provisional; Region: PRK10901
767434008672	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
767434008673	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434008674	S-adenosylmethionine binding site [chemical binding]; other site
767434008675	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
767434008676	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
767434008677	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
767434008678	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
767434008679	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
767434008680	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
767434008681	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
767434008682	active site
767434008683	Pirin-related protein [General function prediction only]; Region: COG1741
767434008684	Pirin; Region: Pirin; pfam02678
767434008685	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
767434008686	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434008687	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434008688	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
767434008689	putative effector binding pocket; other site
767434008690	dimerization interface [polypeptide binding]; other site
767434008691	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
767434008692	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
767434008693	trimer interface [polypeptide binding]; other site
767434008694	putative metal binding site [ion binding]; other site
767434008695	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
767434008696	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
767434008697	active site
767434008698	Zn binding site [ion binding]; other site
767434008699	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
767434008700	putative catalytic site [active]
767434008701	putative phosphate binding site [ion binding]; other site
767434008702	active site
767434008703	metal binding site A [ion binding]; metal-binding site
767434008704	DNA binding site [nucleotide binding]
767434008705	putative AP binding site [nucleotide binding]; other site
767434008706	putative metal binding site B [ion binding]; other site
767434008707	Uncharacterized protein family (UPF0149); Region: UPF0149; pfam03695
767434008708	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
767434008709	AAA domain; Region: AAA_33; pfam13671
767434008710	ATP-binding site [chemical binding]; other site
767434008711	Gluconate-6-phosphate binding site [chemical binding]; other site
767434008712	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
767434008713	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
767434008714	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
767434008715	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
767434008716	P-loop; other site
767434008717	Magnesium ion binding site [ion binding]; other site
767434008718	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
767434008719	ParB-like nuclease domain; Region: ParBc; pfam02195
767434008720	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
767434008721	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
767434008722	Ligand binding site; other site
767434008723	Putative Catalytic site; other site
767434008724	DXD motif; other site
767434008725	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
767434008726	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
767434008727	nucleophile elbow; other site
767434008728	Predicted transcriptional regulator [Transcription]; Region: COG2378
767434008729	HTH domain; Region: HTH_11; pfam08279
767434008730	WYL domain; Region: WYL; pfam13280
767434008731	Protein of unknown function, DUF481; Region: DUF481; pfam04338
767434008732	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
767434008733	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
767434008734	pyridoxal 5'-phosphate binding site [chemical binding]; other site
767434008735	homodimer interface [polypeptide binding]; other site
767434008736	catalytic residue [active]
767434008737	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
767434008738	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
767434008739	Ligand Binding Site [chemical binding]; other site
767434008740	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3416
767434008741	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
767434008742	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
767434008743	HlyD family secretion protein; Region: HlyD_3; pfam13437
767434008744	Protein of unknown function (DUF1656); Region: DUF1656; cl11658
767434008745	Fusaric acid resistance protein family; Region: FUSC; pfam04632
767434008746	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
767434008747	MarR family; Region: MarR_2; cl17246
767434008748	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
767434008749	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
767434008750	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
767434008751	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
767434008752	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
767434008753	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
767434008754	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
767434008755	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
767434008756	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
767434008757	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
767434008758	SCP-2 sterol transfer family; Region: SCP2; pfam02036
767434008759	ABC1 family; Region: ABC1; cl17513
767434008760	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
767434008761	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
767434008762	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
767434008763	active site
767434008764	hypothetical protein; Provisional; Region: PRK09256
767434008765	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
767434008766	Protein of unknown function (DUF962); Region: DUF962; cl01879
767434008767	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
767434008768	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
767434008769	NAD(P) binding site [chemical binding]; other site
767434008770	catalytic residues [active]
767434008771	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
767434008772	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
767434008773	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
767434008774	DNA binding residues [nucleotide binding]
767434008775	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
767434008776	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
767434008777	Protein of unknown function (DUF560); Region: DUF560; pfam04575
767434008778	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
767434008779	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
767434008780	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
767434008781	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
767434008782	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
767434008783	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
767434008784	MgtC family; Region: MgtC; pfam02308
767434008785	short chain dehydrogenase; Provisional; Region: PRK06180
767434008786	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434008787	NAD(P) binding site [chemical binding]; other site
767434008788	active site
767434008789	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434008790	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434008791	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
767434008792	putative effector binding pocket; other site
767434008793	putative dimerization interface [polypeptide binding]; other site
767434008794	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
767434008795	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
767434008796	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434008797	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434008798	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
767434008799	putative effector binding pocket; other site
767434008800	dimerization interface [polypeptide binding]; other site
767434008801	short chain dehydrogenase; Provisional; Region: PRK06500
767434008802	classical (c) SDRs; Region: SDR_c; cd05233
767434008803	NAD(P) binding site [chemical binding]; other site
767434008804	active site
767434008805	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
767434008806	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434008807	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434008808	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
767434008809	Walker A/P-loop; other site
767434008810	ATP binding site [chemical binding]; other site
767434008811	Q-loop/lid; other site
767434008812	ABC transporter signature motif; other site
767434008813	Walker B; other site
767434008814	D-loop; other site
767434008815	H-loop/switch region; other site
767434008816	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
767434008817	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
767434008818	Walker A/P-loop; other site
767434008819	ATP binding site [chemical binding]; other site
767434008820	Q-loop/lid; other site
767434008821	ABC transporter signature motif; other site
767434008822	Walker B; other site
767434008823	D-loop; other site
767434008824	H-loop/switch region; other site
767434008825	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434008826	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434008827	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
767434008828	putative effector binding pocket; other site
767434008829	dimerization interface [polypeptide binding]; other site
767434008830	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
767434008831	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
767434008832	putative NAD(P) binding site [chemical binding]; other site
767434008833	dimer interface [polypeptide binding]; other site
767434008834	Major royal jelly protein; Region: MRJP; pfam03022
767434008835	Cellular and retroviral pepsin-like aspartate proteases; Region: pepsin_retropepsin_like; cl11403
767434008836	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
767434008837	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
767434008838	Transcriptional regulator [Transcription]; Region: LysR; COG0583
767434008839	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
767434008840	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
767434008841	putative effector binding pocket; other site
767434008842	putative dimerization interface [polypeptide binding]; other site
767434008843	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
767434008844	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
767434008845	HlyD family secretion protein; Region: HlyD_3; pfam13437
767434008846	AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873
767434008847	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
767434008848	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
767434008849	dimer interface [polypeptide binding]; other site
767434008850	active site
767434008851	aspartate-rich active site metal binding site; other site
767434008852	allosteric magnesium binding site [ion binding]; other site
767434008853	Schiff base residues; other site
767434008854	Glucokinase; Region: Glucokinase; pfam02685
767434008855	glucokinase, proteobacterial type; Region: glk; TIGR00749
767434008856	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
767434008857	FAD binding domain; Region: FAD_binding_4; pfam01565
767434008858	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
767434008859	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
767434008860	ATP binding site [chemical binding]; other site
767434008861	putative Mg++ binding site [ion binding]; other site
767434008862	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
767434008863	nucleotide binding region [chemical binding]; other site
767434008864	ATP-binding site [chemical binding]; other site
767434008865	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
767434008866	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
767434008867	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
767434008868	preprotein translocase subunit SecB; Validated; Region: PRK05751
767434008869	SecA binding site; other site
767434008870	Preprotein binding site; other site
767434008871	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
767434008872	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
767434008873	alanine racemase; Reviewed; Region: dadX; PRK03646
767434008874	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
767434008875	active site
767434008876	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
767434008877	substrate binding site [chemical binding]; other site
767434008878	catalytic residues [active]
767434008879	dimer interface [polypeptide binding]; other site
767434008880	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
767434008881	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
767434008882	hydroxyglutarate oxidase; Provisional; Region: PRK11728
767434008883	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
767434008884	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
767434008885	putative DNA binding site [nucleotide binding]; other site
767434008886	putative Zn2+ binding site [ion binding]; other site
767434008887	AsnC family; Region: AsnC_trans_reg; pfam01037
767434008888	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cl02915
767434008889	Cl- selectivity filter; other site
767434008890	Cl- binding residues [ion binding]; other site
767434008891	pore gating glutamate residue; other site
767434008892	dimer interface [polypeptide binding]; other site
767434008893	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
767434008894	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
767434008895	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
767434008896	MarR family; Region: MarR; pfam01047
767434008897	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
767434008898	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434008899	3-oxoacyl-(acyl-carrier-protein) reductase, putative; Region: fabG_rel; TIGR01831
767434008900	NAD(P) binding site [chemical binding]; other site
767434008901	active site
767434008902	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
767434008903	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
767434008904	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cd00136
767434008905	protein binding site [polypeptide binding]; other site
767434008906	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
767434008907	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
767434008908	FAD binding pocket [chemical binding]; other site
767434008909	FAD binding motif [chemical binding]; other site
767434008910	phosphate binding motif [ion binding]; other site
767434008911	NAD binding pocket [chemical binding]; other site
767434008912	phospholipase C, phosphocholine-specific, Pseudomonas-type; Region: PC_PLC; TIGR03396
767434008913	Phosphoesterase family; Region: Phosphoesterase; pfam04185
767434008914	Domain of unknown function (DUF756); Region: DUF756; pfam05506
767434008915	Domain of unknown function (DUF756); Region: DUF756; pfam05506
767434008916	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
767434008917	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
767434008918	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
767434008919	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
767434008920	Flavodoxin; Region: Flavodoxin_1; pfam00258
767434008921	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR_like1; cd06200
767434008922	FAD binding pocket [chemical binding]; other site
767434008923	FAD binding motif [chemical binding]; other site
767434008924	catalytic residues [active]
767434008925	NAD binding pocket [chemical binding]; other site
767434008926	phosphate binding motif [ion binding]; other site
767434008927	beta-alpha-beta structure motif; other site
767434008928	amino acid transporter; Region: 2A0306; TIGR00909
767434008929	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
767434008930	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
767434008931	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
767434008932	N-terminal plug; other site
767434008933	ligand-binding site [chemical binding]; other site
767434008934	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
767434008935	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
767434008936	dimerization interface [polypeptide binding]; other site
767434008937	DPS ferroxidase diiron center [ion binding]; other site
767434008938	ion pore; other site
767434008939	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
767434008940	Glycerophosphodiester phosphodiesterase domain of Streptomycin coelicolor (GlpQ1) and similar proteins; Region: GDPD_ScGlpQ1_like; cd08602
767434008941	putative active site [active]
767434008942	catalytic site [active]
767434008943	putative metal binding site [ion binding]; other site
767434008944	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
767434008945	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
767434008946	active site
767434008947	dimer interface [polypeptide binding]; other site
767434008948	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
767434008949	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
767434008950	active site
767434008951	metal binding site [ion binding]; metal-binding site
767434008952	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
767434008953	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
767434008954	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
767434008955	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cl08044
767434008956	AefR-like transcriptional repressor, C-terminal region; Region: TetR_C_7; pfam14246
767434008957	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
767434008958	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
767434008959	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
767434008960	HlyD family secretion protein; Region: HlyD_3; pfam13437
767434008961	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
767434008962	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434008963	putative substrate translocation pore; other site
767434008964	lipase chaperone; Provisional; Region: PRK01294
767434008965	Proteobacterial lipase chaperone protein; Region: Lipase_chap; pfam03280
767434008966	Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075
767434008967	Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075
767434008968	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
767434008969	catalytic site [active]
767434008970	Homoserine dehydrogenase [Amino acid transport and metabolism]; Region: ThrA; COG0460
767434008971	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
767434008972	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
767434008973	homoserine kinase; Provisional; Region: PRK01212
767434008974	threonine synthase; Validated; Region: PRK09225
767434008975	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
767434008976	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
767434008977	catalytic residue [active]
767434008978	2-isopropylmalate synthase; Validated; Region: PRK00915
767434008979	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
767434008980	active site
767434008981	catalytic residues [active]
767434008982	metal binding site [ion binding]; metal-binding site
767434008983	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
767434008984	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
767434008985	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
767434008986	substrate binding site [chemical binding]; other site
767434008987	ligand binding site [chemical binding]; other site
767434008988	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
767434008989	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
767434008990	substrate binding site [chemical binding]; other site
767434008991	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
767434008992	tartrate dehydrogenase; Region: TTC; TIGR02089
767434008993	ketol-acid reductoisomerase; Provisional; Region: PRK05479
767434008994	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
767434008995	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
767434008996	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
767434008997	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
767434008998	PYR/PP interface [polypeptide binding]; other site
767434008999	dimer interface [polypeptide binding]; other site
767434009000	TPP binding site [chemical binding]; other site
767434009001	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
767434009002	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
767434009003	TPP-binding site [chemical binding]; other site
767434009004	dimer interface [polypeptide binding]; other site
767434009005	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
767434009006	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
767434009007	putative valine binding site [chemical binding]; other site
767434009008	dimer interface [polypeptide binding]; other site
767434009009	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
767434009010	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
767434009011	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
767434009012	metal binding site [ion binding]; metal-binding site
767434009013	active site
767434009014	I-site; other site
767434009015	hopene-associated glycosyltransferase HpnB; Region: HpnB; TIGR03469
767434009016	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
767434009017	active site
767434009018	hopanoid biosynthesis associated radical SAM protein HpnH; Region: HpnH; TIGR03470
767434009019	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
767434009020	FeS/SAM binding site; other site
767434009021	Domain of unknown function (DUF3463); Region: DUF3463; pfam11946
767434009022	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
767434009023	isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150
767434009024	active site
767434009025	metal binding site [ion binding]; metal-binding site
767434009026	nudix motif; other site
767434009027	Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis; Region: Glucosylceramide_synthase; cd02520
767434009028	ligand binding site; other site
767434009029	Glycosyl transferase family 21; Region: Glyco_transf_21; pfam13506
767434009030	hopanoid biosynthesis associated radical SAM protein HpnJ; Region: HpnJ; TIGR03471
767434009031	B12 binding domain; Region: B12-binding; pfam02310
767434009032	B12 binding site [chemical binding]; other site
767434009033	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
767434009034	FeS/SAM binding site; other site
767434009035	hopanoid biosynthesis associated protein HpnK and similar proteins; Region: YdjC_HpnK_like; cd10804
767434009036	putative active site [active]
767434009037	YdjC motif; other site
767434009038	Mg binding site [ion binding]; other site
767434009039	putative homodimer interface [polypeptide binding]; other site
767434009040	Uncharacterized protein family (UPF0104); Region: UPF0104; cl04219
767434009041	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
767434009042	uncharacterized subgroup of aldehyde reductase and flavonoid reductase related proteins, extended (e) SDRs; Region: AR_FR_like_1_SDR_e; cd05228
767434009043	putative NADP binding site [chemical binding]; other site
767434009044	putative substrate binding site [chemical binding]; other site
767434009045	active site
767434009046	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
767434009047	active site lid residues [active]
767434009048	substrate binding pocket [chemical binding]; other site
767434009049	catalytic residues [active]
767434009050	substrate-Mg2+ binding site; other site
767434009051	aspartate-rich region 1; other site
767434009052	aspartate-rich region 2; other site
767434009053	Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY)  and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; Region: SQCY_1; cd02892
767434009054	squalene-hopene cyclase; Region: hopene_cyclase; TIGR01507
767434009055	Active site cavity [active]
767434009056	catalytic acid [active]
767434009057	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
767434009058	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
767434009059	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
767434009060	substrate binding pocket [chemical binding]; other site
767434009061	chain length determination region; other site
767434009062	substrate-Mg2+ binding site; other site
767434009063	catalytic residues [active]
767434009064	aspartate-rich region 1; other site
767434009065	active site lid residues [active]
767434009066	aspartate-rich region 2; other site
767434009067	Carbohydrate-selective porin, OprB family; Region: OprB; cl17816
767434009068	Carbohydrate-selective porin, OprB family; Region: OprB; cl17816
767434009069	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
767434009070	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
767434009071	catalytic residue [active]
767434009072	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
767434009073	catalytic residues [active]
767434009074	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
767434009075	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
767434009076	peroxiredoxin; Region: AhpC; TIGR03137
767434009077	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
767434009078	dimer interface [polypeptide binding]; other site
767434009079	decamer (pentamer of dimers) interface [polypeptide binding]; other site
767434009080	catalytic triad [active]
767434009081	peroxidatic and resolving cysteines [active]
767434009082	D-ribose pyranase; Provisional; Region: PRK11797
767434009083	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
767434009084	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
767434009085	substrate binding site [chemical binding]; other site
767434009086	dimer interface [polypeptide binding]; other site
767434009087	ATP binding site [chemical binding]; other site
767434009088	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
767434009089	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
767434009090	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
767434009091	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
767434009092	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
767434009093	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
767434009094	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
767434009095	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
767434009096	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
767434009097	meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs; Region: meso-BDH-like_SDR_c; cd05366
767434009098	acetoin reductases; Region: 23BDH; TIGR02415
767434009099	NAD binding site [chemical binding]; other site
767434009100	homotetramer interface [polypeptide binding]; other site
767434009101	homodimer interface [polypeptide binding]; other site
767434009102	active site
767434009103	substrate binding site [chemical binding]; other site
767434009104	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
767434009105	Fatty acid desaturase; Region: FA_desaturase; pfam00487
767434009106	Di-iron ligands [ion binding]; other site
767434009107	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
767434009108	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
767434009109	DNA binding site [nucleotide binding]
767434009110	catalytic residue [active]
767434009111	H2TH interface [polypeptide binding]; other site
767434009112	putative catalytic residues [active]
767434009113	turnover-facilitating residue; other site
767434009114	intercalation triad [nucleotide binding]; other site
767434009115	8OG recognition residue [nucleotide binding]; other site
767434009116	putative reading head residues; other site
767434009117	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
767434009118	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
767434009119	thymidine kinase; Provisional; Region: PRK04296
767434009120	ATP-dependent DNA helicase Rep; Region: rep; TIGR01074
767434009121	Part of AAA domain; Region: AAA_19; pfam13245
767434009122	Family description; Region: UvrD_C_2; pfam13538
767434009123	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
767434009124	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
767434009125	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
767434009126	putative acyl-acceptor binding pocket; other site
767434009127	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
767434009128	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
767434009129	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434009130	S-adenosylmethionine binding site [chemical binding]; other site
767434009131	Acyltransferase family; Region: Acyl_transf_3; pfam01757
767434009132	spermidine synthase; Provisional; Region: PRK00811
767434009133	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
767434009134	S-adenosylmethionine binding site [chemical binding]; other site
767434009135	arginine decarboxylase; Provisional; Region: PRK05354
767434009136	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
767434009137	dimer interface [polypeptide binding]; other site
767434009138	active site
767434009139	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
767434009140	catalytic residues [active]
767434009141	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
767434009142	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
767434009143	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434009144	putative substrate translocation pore; other site
767434009145	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434009146	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
767434009147	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434009148	putative substrate translocation pore; other site
767434009149	Fusaric acid resistance protein family; Region: FUSC; pfam04632
767434009150	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
767434009151	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
767434009152	metal binding site [ion binding]; metal-binding site
767434009153	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
767434009154	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434009155	putative substrate translocation pore; other site
767434009156	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
767434009157	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
767434009158	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
767434009159	HlyD family secretion protein; Region: HlyD_3; pfam13437
767434009160	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
767434009161	Transcriptional regulators [Transcription]; Region: MarR; COG1846
767434009162	MarR family; Region: MarR; pfam01047
767434009163	MarR family; Region: MarR_2; cl17246
767434009164	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
767434009165	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
767434009166	putative hydrolase; Provisional; Region: PRK11460
767434009167	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
767434009168	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
767434009169	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
767434009170	domain interfaces; other site
767434009171	active site
767434009172	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
767434009173	catalytic core [active]
767434009174	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
767434009175	PLD-like domain; Region: PLDc_2; pfam13091
767434009176	putative active site [active]
767434009177	catalytic site [active]
767434009178	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
767434009179	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
767434009180	putative active site [active]
767434009181	catalytic site [active]
767434009182	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
767434009183	nitrogen regulation protein NR(I); Region: ntrC; TIGR01818
767434009184	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
767434009185	active site
767434009186	phosphorylation site [posttranslational modification]
767434009187	intermolecular recognition site; other site
767434009188	dimerization interface [polypeptide binding]; other site
767434009189	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
767434009190	Walker A motif; other site
767434009191	ATP binding site [chemical binding]; other site
767434009192	Walker B motif; other site
767434009193	arginine finger; other site
767434009194	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
767434009195	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
767434009196	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
767434009197	ATP binding site [chemical binding]; other site
767434009198	G-X-G motif; other site
767434009199	glutamine synthetase; Provisional; Region: glnA; PRK09469
767434009200	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
767434009201	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
767434009202	Bacterial protein of unknown function (Gcw_chp); Region: Gcw_chp; cl09901
767434009203	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
767434009204	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
767434009205	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
767434009206	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
767434009207	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
767434009208	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
767434009209	active site
767434009210	substrate binding site [chemical binding]; other site
767434009211	metal binding site [ion binding]; metal-binding site
767434009212	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
767434009213	trimer interface [polypeptide binding]; other site
767434009214	active site
767434009215	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
767434009216	Flavoprotein; Region: Flavoprotein; pfam02441
767434009217	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
767434009218	hypothetical protein; Reviewed; Region: PRK00024
767434009219	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
767434009220	MPN+ (JAMM) motif; other site
767434009221	Zinc-binding site [ion binding]; other site
767434009222	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
767434009223	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
767434009224	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
767434009225	active site
767434009226	HIGH motif; other site
767434009227	KMSK motif region; other site
767434009228	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
767434009229	tRNA binding surface [nucleotide binding]; other site
767434009230	anticodon binding site; other site
767434009231	Sporulation related domain; Region: SPOR; pfam05036
767434009232	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
767434009233	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
767434009234	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
767434009235	DNA binding residues [nucleotide binding]
767434009236	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
767434009237	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
767434009238	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
767434009239	Protein export membrane protein; Region: SecD_SecF; cl14618
767434009240	Type III secretion system lipoprotein chaperone (YscW); Region: YscW; cl15825
767434009241	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
767434009242	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
767434009243	Ligand binding site; other site
767434009244	DXD motif; other site
767434009245	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
767434009246	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
767434009247	oxidoreductase; Validated; Region: PRK05717
767434009248	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
767434009249	NAD(P) binding site [chemical binding]; other site
767434009250	active site
767434009251	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
767434009252	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
767434009253	putative active site [active]
767434009254	metal binding site [ion binding]; metal-binding site
767434009255	putative hydrolase; Provisional; Region: PRK11460
767434009256	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
767434009257	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
767434009258	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
767434009259	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
767434009260	active site
767434009261	RNA polymerase sigma factor, TIGR02999 family; Region: Sig-70_X6
767434009262	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
767434009263	Catalytic domain of Protein Kinases; Region: PKc; cd00180
767434009264	active site
767434009265	ATP binding site [chemical binding]; other site
767434009266	substrate binding site [chemical binding]; other site
767434009267	activation loop (A-loop); other site
767434009268	Tetratricopeptide repeat; Region: TPR_12; pfam13424
767434009269	Tetratricopeptide repeat; Region: TPR_12; pfam13424
767434009270	Tetratricopeptide repeat; Region: TPR_10; pfam13374
767434009271	Helix-turn-helix domain; Region: HTH_18; pfam12833
767434009272	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434009273	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
767434009274	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
767434009275	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
767434009276	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
767434009277	trmE is a tRNA modification GTPase; Region: trmE; cd04164
767434009278	G1 box; other site
767434009279	GTP/Mg2+ binding site [chemical binding]; other site
767434009280	Switch I region; other site
767434009281	G2 box; other site
767434009282	Switch II region; other site
767434009283	G3 box; other site
767434009284	G4 box; other site
767434009285	G5 box; other site
767434009286	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
767434009287	membrane protein insertase; Provisional; Region: PRK01318
767434009288	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
767434009289	Ribonuclease P; Region: Ribonuclease_P; pfam00825
767434009290	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399