-- dump date 20140619_102555 -- class Genbank::CDS -- table cds_note -- id note YP_001228792.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001228793.1 TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain YP_001228794.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001228795.1 TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II YP_001228796.1 TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal repeat, beta-propeller YP_001228798.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001228799.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001228800.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001228801.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001228802.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein YP_001228803.1 TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001228804.1 PFAM: ABC-2 type transporter YP_001228805.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001228806.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001228808.1 PFAM: protein of unknown function DUF323; Methyltransferase type 11; Methyltransferase type 12 YP_001228809.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001228811.1 PFAM: heat shock protein DnaJ domain protein YP_001228813.1 PFAM: Hsp33 protein YP_001228815.1 PFAM: peptidase U32 YP_001228816.1 PFAM: ATP-binding region, ATPase domain protein YP_001228818.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001228819.1 PFAM: protein of unknown function DUF882; Peptidase M15A YP_001228820.1 PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type YP_001228822.1 PFAM: peptidase M16 domain protein YP_001228823.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein YP_001228824.1 PFAM: Precorrin-8X methylmutase CbiC/CobH YP_001228825.1 TIGRFAM: cobalamin biosynthesis protein CbiD; PFAM: cobalamin (vitamin B12) biosynthesis CbiD protein YP_001228826.1 TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001228827.1 TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001228828.1 TIGRFAM: prevent-host-death family protein YP_001228829.1 PFAM: PilT protein domain protein YP_001228830.1 TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001228831.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein YP_001228832.1 TIGRFAM: cobyric acid synthase CobQ; precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Cobyrinic acid a,c-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase YP_001228833.1 TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB YP_001228834.1 TIGRFAM: putative L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase, class I and II; aminotransferase class-III YP_001228835.1 PFAM: type IV pilus assembly PilZ YP_001228836.1 PFAM: ferric-uptake regulator YP_001228837.1 PFAM: periplasmic solute binding protein YP_001228838.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001228839.1 PFAM: ABC-3 protein YP_001228840.1 PFAM: response regulator receiver YP_001228841.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001228842.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001228843.1 PFAM: extracellular solute-binding protein, family 1 YP_001228844.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001228845.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001228846.1 PFAM: CMP/dCMP deaminase, zinc-binding YP_001228849.1 PFAM: Integrase, catalytic region YP_001228855.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase YP_001228856.1 PFAM: Integrase, catalytic region YP_001228857.1 PFAM: coagulation factor 5/8 type domain protein; Fibronectin, type III domain protein YP_001228859.1 PFAM: APHP domain protein; WD40 domain protein beta Propeller YP_001228860.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001228861.1 TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase YP_001228862.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_001228863.1 PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP YP_001228864.1 TIGRFAM: cytochrome C family protein YP_001228865.1 TIGRFAM: cytochrome C family protein YP_001228866.1 TIGRFAM: cytochrome C family protein YP_001228868.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001228869.1 PFAM: Heavy metal transport/detoxification protein YP_001228871.1 PFAM: protein of unknown function DUF214 YP_001228872.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001228873.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001228874.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001228876.1 PFAM: outer membrane efflux protein YP_001228877.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001228878.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein YP_001228883.1 PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2 YP_001228884.1 PFAM: alpha/beta hydrolase fold YP_001228885.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase YP_001228888.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001228893.1 PFAM: Ankyrin YP_001228894.1 PFAM: TPR repeat-containing protein; Sel1 domain protein repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001228895.1 PFAM: transposase, mutator type YP_001228896.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001228897.1 PFAM: transposase, mutator type YP_001228900.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal YP_001228901.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001228902.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001228903.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001228904.1 PFAM: inner-membrane translocator YP_001228905.1 PFAM: inner-membrane translocator YP_001228906.1 PFAM: Extracellular ligand-binding receptor YP_001228907.1 TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; AAA ATPase YP_001228908.1 TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III YP_001228909.1 TIGRFAM: cytochrome C family protein YP_001228910.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001228911.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001228913.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001228917.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001228918.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger, DksA/TraR C4-type YP_001228919.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001228920.1 PFAM: PBS lyase HEAT domain protein repeat-containing protein YP_001228921.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001228922.1 PFAM: HEAT domain containing protein; PBS lyase HEAT domain protein repeat-containing protein YP_001228924.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III YP_001228928.1 PFAM: transposase, IS4 family protein YP_001228929.1 TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001228930.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001228931.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001228932.1 PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein YP_001228933.1 TIGRFAM: protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase YP_001228934.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001228935.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001228936.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001228937.1 PFAM: methyl-viologen-reducing hydrogenase, delta subunit YP_001228938.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001228939.1 PFAM: protein of unknown function DUF224, cysteine-rich region domain protein YP_001228941.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF162; protein of unknown function DUF224, cysteine-rich region domain protein YP_001228942.1 PFAM: protein of unknown function DUF162 YP_001228943.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease YP_001228944.1 TIGRFAM: succinyl-CoA synthetase, beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein YP_001228945.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase YP_001228947.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001228948.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001228949.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001228953.1 TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; small GTP-binding protein domain YP_001228954.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001228955.1 PFAM: response regulator receiver YP_001228957.1 PFAM: isochorismatase hydrolase YP_001228958.1 PFAM: PilT protein domain protein YP_001228959.1 TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein YP_001228960.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001228962.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001228963.1 PFAM: cyclase family protein YP_001228964.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001228965.1 PFAM: NUDIX hydrolase YP_001228966.1 PFAM: protein of unknown function DUF1458 YP_001228967.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001228968.1 PFAM: Rubrerythrin YP_001228969.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001228971.1 PFAM: SEC-C motif domain protein YP_001228972.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001228973.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain YP_001228974.1 TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: ribonucleotide reductase large subunit; Ribonucleotide reductase large subunit, N terminal domain protein YP_001228976.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5 YP_001228977.1 PFAM: protein of unknown function DUF58 YP_001228978.1 PFAM: transglutaminase domain protein YP_001228979.1 TIGRFAM: MJ0042 family finger-like protein YP_001228980.1 PFAM: phospholipase D/Transphosphatidylase YP_001228982.1 TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44 YP_001228983.1 PFAM: ribulose-phosphate 3-epimerase YP_001228984.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver YP_001228985.1 PFAM: HhH-GPD family protein YP_001228988.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001228989.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001228990.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001228991.1 PFAM: OmpA/MotB domain protein YP_001228992.1 PFAM: WD40 domain protein beta Propeller YP_001228993.1 TIGRFAM: TonB family protein YP_001228994.1 PFAM: Biopolymer transport protein ExbD/TolR YP_001228995.1 PFAM: MotA/TolQ/ExbB proton channel YP_001228996.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001228997.1 TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001228998.1 TIGRFAM: heat-inducible transcription repressor HrcA; PFAM: Negative regulator of class I heat shock protein YP_001228999.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001229000.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001229001.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001229002.1 PFAM: phospholipase D/Transphosphatidylase YP_001229004.1 PFAM: protein of unknown function DUF111 YP_001229005.1 PFAM: phosphatidylglycerophosphatase A YP_001229006.1 TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein YP_001229007.1 TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001229008.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001229009.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E YP_001229010.1 PFAM: regulatory protein RecX YP_001229011.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001229012.1 PFAM: Cupin 2, conserved barrel domain protein YP_001229013.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001229014.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001229015.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001229016.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001229017.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001229018.1 PFAM: NUDIX hydrolase YP_001229020.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001229021.1 PFAM: Fibronectin, type III domain protein YP_001229022.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2 YP_001229023.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001229024.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001229025.1 PFAM: DNA polymerase, beta domain protein region YP_001229026.1 PFAM: HEPN domain protein YP_001229027.1 catalyzes the interconversion of tetrahydrodipicolinate and L,L-diaminopimelate in lysine biosynthesis YP_001229030.1 PFAM: DNA polymerase, beta domain protein region YP_001229032.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001229033.1 PFAM: transposase, mutator type YP_001229034.1 PFAM: transposase, IS4 family protein YP_001229035.1 PFAM: protein of unknown function UPF0153 YP_001229038.1 PFAM: major facilitator superfamily MFS_1 YP_001229039.1 PFAM: protein of unknown function DUF45 YP_001229040.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001229041.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001229043.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001229045.1 PFAM: major facilitator superfamily MFS_1 YP_001229046.1 PFAM: pseudouridine synthase YP_001229048.1 PFAM: helix-turn-helix domain protein YP_001229049.1 PFAM: thioesterase superfamily protein YP_001229050.1 PFAM: Endonuclease V YP_001229051.1 PFAM: protein of unknown function DUF1653 YP_001229052.1 PFAM: protein of unknown function UPF0126 YP_001229054.1 TIGRFAM: PAS sensor protein; PFAM: CHASE4 domain protein; PAS fold-4 domain protein; PAS fold domain protein YP_001229055.1 PFAM: beta-lactamase domain protein YP_001229056.1 PFAM: PEBP family protein YP_001229057.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001229058.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001229060.1 PFAM: major facilitator superfamily MFS_1 YP_001229062.1 PFAM: dihydrouridine synthase, DuS YP_001229063.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001229064.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001229065.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001229066.1 PFAM: protein of unknown function DUF480 YP_001229067.1 PFAM: ATP-binding region, ATPase domain protein YP_001229068.1 PFAM: NUDIX hydrolase YP_001229070.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; HDOD; SMART: metal-dependent phosphohydrolase, HD region YP_001229071.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001229074.1 TIGRFAM: 2'-5' RNA ligase; PFAM: 2',5' RNA ligase YP_001229076.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001229078.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001229079.1 PFAM: response regulator receiver YP_001229080.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001229081.1 TIGRFAM: poly(A) polymerase; PFAM: Polynucleotide adenylyltransferase region YP_001229083.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229084.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001229085.1 PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B YP_001229089.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001229090.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein YP_001229091.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001229092.1 PFAM: Rieske [2Fe-2S] domain protein YP_001229093.1 PFAM: ribosomal protein L21 YP_001229094.1 involved in the peptidyltransferase reaction during translation YP_001229095.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001229096.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; Ig family protein YP_001229097.1 PFAM: PilT protein domain protein; SMART: Nucleotide binding protein, PINc YP_001229100.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172 YP_001229101.1 TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin, Txe/YoeB YP_001229102.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001229103.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001229107.1 PFAM: Integrase, catalytic region YP_001229108.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001229109.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I) YP_001229110.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L YP_001229111.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 YP_001229112.1 Catalyzes the transfer of electrons from NADH to quinone YP_001229114.1 PFAM: respiratory-chain NADH dehydrogenase, subunit 1 YP_001229115.1 Catalyzes the transfer of electrons from NADH to quinone YP_001229116.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001229117.1 PFAM: 4-vinyl reductase, 4VR YP_001229118.1 PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit YP_001229119.1 PFAM: protein of unknown function DUF488 YP_001229120.1 PFAM: cytochrome c, class I YP_001229121.1 Catalyzes the transfer of electrons from NADH to quinone YP_001229122.1 NuoBCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex YP_001229123.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_001229124.1 PFAM: Thioredoxin domain; Contains selenocysteine YP_001229125.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein YP_001229126.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein YP_001229127.1 TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein YP_001229128.1 TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel YP_001229129.1 PFAM: CMP/dCMP deaminase, zinc-binding YP_001229130.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001229131.1 PFAM: RNA-binding S4 domain protein YP_001229132.1 involved in start site selection during the initiation of translation YP_001229133.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein YP_001229134.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_001229135.1 PFAM: Cupin 2, conserved barrel domain protein YP_001229136.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001229138.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001229139.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein YP_001229140.1 PFAM: protein of unknown function DUF362 YP_001229141.1 PFAM: plasmid stabilization system YP_001229142.1 TIGRFAM: putative addiction module component, TIGR02574 family YP_001229143.1 PFAM: DNA polymerase, beta domain protein region YP_001229147.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4 YP_001229148.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001229149.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001229150.1 PFAM: cytochrome c assembly protein YP_001229151.1 TIGRFAM: siroheme synthase YP_001229152.1 TIGRFAM: thioredoxin; PFAM: Redoxin domain protein; Thioredoxin domain YP_001229153.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Thioredoxin domain YP_001229154.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001229156.1 PFAM: Peptidoglycan-binding LysM YP_001229159.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001229160.1 PFAM: beta-lactamase domain protein; flavodoxin/nitric oxide synthase YP_001229161.1 PFAM: DNA polymerase, beta domain protein region YP_001229163.1 TIGRFAM: primosomal protein N'; PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001229164.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001229165.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001229167.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001229170.1 PFAM: sodium:dicarboxylate symporter YP_001229171.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Contains selenocysteine YP_001229172.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; Fibronectin, type III domain protein; Cna B domain protein; APHP domain protein; SMART: Immunoglobulin subtype YP_001229175.1 SMART: PAS domain containing protein YP_001229176.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein YP_001229182.1 PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase YP_001229183.1 TIGRFAM: acetate kinase; PFAM: acetate and butyrate kinase YP_001229184.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001229185.1 PFAM: biotin/lipoate A/B protein ligase YP_001229187.1 TIGRFAM: cytochrome C family protein YP_001229188.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001229189.1 PFAM: peptidase M23B YP_001229190.1 PFAM: protein of unknown function DUF309 YP_001229193.1 PFAM: UbiA prenyltransferase YP_001229194.1 PFAM: cytochrome oxidase assembly YP_001229195.1 TIGRFAM: caa(3)-type oxidase, subunit IV YP_001229196.1 PFAM: cytochrome c oxidase, subunit III YP_001229197.1 PFAM: cytochrome c oxidase, subunit I YP_001229198.1 PFAM: DNA polymerase, beta domain protein region YP_001229200.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein-like YP_001229201.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein YP_001229202.1 PFAM: plasmid maintenance system killer YP_001229203.1 TIGRFAM: cytochrome C oxidase subunit II, transmembrane region; PFAM: cytochrome c oxidase, subunit II; cytochrome c, class I YP_001229207.1 PFAM: V-type ATPase, 116 kDa subunit YP_001229208.1 PFAM: H+-transporting two-sector ATPase, C subunit YP_001229209.1 PFAM: H+-transporting two-sector ATPase, E subunit YP_001229210.1 PFAM: Vacuolar H+-transporting two-sector ATPase, F subunit YP_001229211.1 PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; H+-transporting two-sector ATPase, alpha/beta subunit domain protein YP_001229212.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001229213.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the B subunit is part of the catalytic core of the ATP synthase complex YP_001229214.1 TIGRFAM: V-type ATPase, D subunit; PFAM: H+-transporting two-sector ATPase, D subunit YP_001229215.1 PFAM: filamentation induced by cAMP protein Fic YP_001229216.1 PFAM: MscS Mechanosensitive ion channel YP_001229217.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region YP_001229218.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229219.1 PFAM: Rubrerythrin YP_001229220.1 SMART: PAS domain containing protein YP_001229221.1 PFAM: protein of unknown function DUF542, ScdA domain protein; Hemerythrin HHE cation binding domain protein YP_001229222.1 PFAM: Radical SAM domain protein YP_001229223.1 PFAM: cytochrome c biogenesis protein, transmembrane region YP_001229224.1 PFAM: Thioredoxin domain YP_001229225.1 TIGRFAM: redox-active disulfide protein 2 YP_001229226.1 SMART: Rhodanese domain protein YP_001229227.1 PFAM: permease YP_001229228.1 PFAM: regulatory protein, ArsR YP_001229229.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229231.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001229232.1 PFAM: transposase, IS4 family protein YP_001229233.1 SMART: Rhodanese domain protein YP_001229234.1 PFAM: phosphate-selective porin O and P YP_001229238.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001229239.1 SMART: Rhodanese domain protein YP_001229240.1 PFAM: phosphate-selective porin O and P YP_001229246.1 PFAM: Rieske [2Fe-2S] domain protein YP_001229247.1 PFAM: Cytochrome b/b6, N-terminal domain YP_001229251.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV YP_001229252.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region YP_001229255.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001229256.1 TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter YP_001229257.1 PFAM: regulatory protein, ArsR YP_001229259.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001229260.1 PFAM: cytoplasmic chaperone TorD family protein YP_001229261.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229262.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229264.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001229265.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001229266.1 PFAM: adenosine/AMP deaminase YP_001229267.1 PFAM: regulatory protein, MarR YP_001229269.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229272.1 TIGRFAM: putative CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type YP_001229273.1 PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component YP_001229275.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001229277.1 PFAM: dihydropteroate synthase, DHPS; homocysteine S-methyltransferase; Methionine synthase, B12-binding module, cap domain protein; cobalamin B12-binding domain protein YP_001229279.1 PFAM: Transketolase domain protein YP_001229280.1 PFAM: Transketolase, central region; Transketolase domain protein YP_001229282.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001229283.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001229284.1 PFAM: NHL repeat containing protein YP_001229285.1 TIGRFAM: cytochrome C family protein YP_001229286.1 TIGRFAM: cytochrome C family protein YP_001229287.1 TIGRFAM: cytochrome C family protein YP_001229288.1 TIGRFAM: cytochrome C family protein YP_001229290.1 PFAM: glycosyl transferase, family 39 YP_001229292.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001229293.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001229294.1 PFAM: Radical SAM domain protein YP_001229295.1 PFAM: glycosyl transferase, family 9 YP_001229296.1 PFAM: glycosyl transferase, family 2 YP_001229297.1 PFAM: Radical SAM domain protein YP_001229299.1 PFAM: cytochrome c assembly protein YP_001229301.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001229304.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001229306.1 PFAM: OmpA/MotB domain protein YP_001229308.1 TIGRFAM: cytochrome C family protein YP_001229310.1 PFAM: cytochrome c assembly protein YP_001229311.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229313.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001229314.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001229315.1 PFAM: acriflavin resistance protein YP_001229317.1 PFAM: regulatory protein, IclR YP_001229319.1 PFAM: regulatory protein, IclR YP_001229320.1 PFAM: outer membrane efflux protein; Sporulation domain protein YP_001229322.1 TIGRFAM: putative ribonuclease BN; PFAM: ribonuclease BN YP_001229323.1 PFAM: purine or other phosphorylase, family 1 YP_001229324.1 PFAM: amidohydrolase 2 YP_001229328.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001229329.1 TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; hydrogenase maturation peptidase superfamily; PFAM: peptidase M52, hydrogen uptake protein YP_001229330.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561 YP_001229331.1 PFAM: nickel-dependent hydrogenase, large subunit YP_001229332.1 TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein YP_001229334.1 PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like YP_001229335.1 PFAM: N-6 DNA methylase YP_001229336.1 PFAM: restriction modification system DNA specificity domain YP_001229338.1 PFAM: sigma-54 factor, interaction domain-containing protein; GAF domain protein YP_001229340.1 PFAM: beta-lactamase domain protein YP_001229341.1 PFAM: protein of unknown function UPF0150 YP_001229342.1 PFAM: YcfA family protein YP_001229345.1 PFAM: IstB domain protein ATP-binding protein; IstB ATP binding N-terminal domain protein; SMART: AAA ATPase YP_001229346.1 PFAM: Integrase, catalytic region YP_001229347.1 PFAM: putative transposase YP_001229348.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001229354.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001229356.1 PFAM: protein of unknown function DUF195 YP_001229357.1 PFAM: alpha/beta hydrolase fold YP_001229358.1 TIGRFAM: cytochrome C family protein YP_001229359.1 PFAM: Fibronectin, type III domain protein; SMART: LamG domain protein jellyroll fold domain protein YP_001229362.1 PFAM: type IV pilus assembly PilZ YP_001229363.1 TIGRFAM: exodeoxyribonuclease V, alpha subunit YP_001229364.1 TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase YP_001229366.1 PFAM: protein of unknown function DUF497 YP_001229367.1 TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V, RecC subunit YP_001229368.1 TIGRFAM: homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold YP_001229371.1 PFAM: HEPN domain protein YP_001229373.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_001229376.1 PFAM: helix-turn-helix domain protein YP_001229377.1 PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases-like YP_001229378.1 PFAM: DNA methylase N-4/N-6 domain protein YP_001229380.1 PFAM: PilT protein domain protein YP_001229382.1 PFAM: filamentation induced by cAMP protein Fic YP_001229383.1 PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases-like YP_001229385.1 PFAM: protein of unknown function UPF0150 YP_001229386.1 PFAM: YcfA family protein YP_001229388.1 PFAM: Activator of Hsp90 ATPase 1 family protein YP_001229391.1 PFAM: zinc finger, SWIM domain protein YP_001229392.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein YP_001229394.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001229395.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001229396.1 PFAM: Appr-1-p processing domain protein YP_001229397.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001229400.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001229401.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229403.1 TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane YP_001229404.1 PFAM: LytTr DNA-binding region YP_001229405.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein YP_001229407.1 PFAM: regulatory protein, LuxR YP_001229408.1 PFAM: Cupin 2, conserved barrel domain protein YP_001229409.1 PFAM: protein of unknown function DUF161 YP_001229411.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229413.1 PFAM: methyltransferase small; Methyltransferase type 11; Methyltransferase type 12 YP_001229415.1 TIGRFAM: prevent-host-death family protein YP_001229417.1 PFAM: protein of unknown function UPF0118 YP_001229418.1 PFAM: protein of unknown function UPF0118 YP_001229420.1 PFAM: metallophosphoesterase YP_001229421.1 PFAM: protein of unknown function UPF0153 YP_001229422.1 PFAM: penicillin-binding protein, transpeptidase YP_001229423.1 TIGRFAM: putative ribonuclease BN; PFAM: protein of unknown function UPF0074; ribonuclease BN YP_001229429.1 PFAM: multiple antibiotic resistance (MarC)-related protein YP_001229430.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001229431.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient YP_001229433.1 PFAM: FAD linked oxidase domain protein YP_001229434.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein YP_001229435.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001229436.1 PFAM: carboxyl transferase YP_001229437.1 PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding YP_001229439.1 TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase YP_001229440.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001229443.1 PFAM: DNA polymerase, beta domain protein region YP_001229444.1 PFAM: protein of unknown function DUF86 YP_001229446.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_001229447.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001229448.2 catalyzes the reduction of hydroxylamine to ammonia and water YP_001229450.1 PFAM: cytochrome c552 YP_001229451.1 PFAM: HPP family protein+B94 YP_001229452.1 PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type YP_001229453.1 PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein YP_001229455.1 PFAM: peptidase M48, Ste24p YP_001229456.1 PFAM: peptidase M48, Ste24p YP_001229460.1 TIGRFAM: general secretion pathway protein L YP_001229461.1 PFAM: General secretion pathway protein K YP_001229465.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G YP_001229466.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein YP_001229467.1 TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; SMART: AAA ATPase YP_001229468.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein YP_001229470.1 PFAM: purine or other phosphorylase, family 1 YP_001229471.1 PFAM: protein of unknown function DUF191 YP_001229472.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001229473.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A YP_001229474.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001229475.1 PFAM: heat shock protein Hsp20 YP_001229476.1 TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001229477.1 TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein YP_001229478.1 PFAM: protein of unknown function UPF0047 YP_001229480.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001229482.1 PFAM: acyltransferase 3 YP_001229485.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein YP_001229486.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_001229488.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_001229491.1 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions YP_001229493.1 PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region YP_001229494.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001229495.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229496.1 PFAM: PilT protein domain protein YP_001229497.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172 YP_001229498.1 PFAM: zinc finger, DksA/TraR C4-type YP_001229499.1 TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme YliG; PFAM: deoxyribonuclease/rho motif-related TRAM; Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB YP_001229500.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001229501.1 PFAM: outer membrane lipoprotein carrier protein LolA YP_001229502.1 PFAM: outer membrane lipoprotein carrier protein LolA YP_001229503.1 PFAM: CheC domain protein YP_001229504.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein YP_001229505.1 PFAM: response regulator receiver YP_001229506.1 PFAM: CheW domain protein YP_001229507.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001229508.1 PFAM: MCP methyltransferase, CheR-type YP_001229509.1 PFAM: type IV pilus assembly PilZ YP_001229510.1 PFAM: transport-associated protein YP_001229513.1 PFAM: aminotransferase, class I and II YP_001229516.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001229519.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001229520.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region YP_001229521.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2 YP_001229522.1 PFAM: Cna B domain protein YP_001229523.1 PFAM: Fibronectin, type III domain protein; protein of unknown function DUF1566 YP_001229524.1 PFAM: protein of unknown function DUF1566 YP_001229526.1 PFAM: ATP-binding region, ATPase domain protein; Diverse 7TM receptor, transmembrane region; histidine kinase, dimerisation and phosphoacceptor region YP_001229527.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001229531.1 PFAM: GCN5-related N-acetyltransferase YP_001229535.1 PFAM: phage Tail Collar domain protein YP_001229536.1 PFAM: phage Tail Collar domain protein YP_001229537.1 PFAM: coagulation factor 5/8 type domain protein YP_001229538.1 TIGRFAM: polymorphic outer membrane protein; PFAM: cell surface receptor IPT/TIG domain protein; Polymorphic membrane protein, Chlamydia; Fibronectin, type III domain protein YP_001229541.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001229542.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001229543.1 PFAM: pentapeptide repeat protein; glycosyl hydrolase, BNR repeat-containing protein YP_001229547.1 PFAM: Tetratricopeptide TPR_4 YP_001229552.1 PFAM: Hemerythrin HHE cation binding domain protein YP_001229553.1 Inhibits transcription at high concentrations of nickel YP_001229554.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein YP_001229555.1 PFAM: CobN/magnesium chelatase YP_001229559.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001229560.1 PFAM: Carbohydrate-selective porin OprB YP_001229561.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein YP_001229562.1 PFAM: Sel1 domain protein repeat-containing protein YP_001229563.1 PFAM: thioesterase superfamily protein YP_001229565.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001229566.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001229567.1 PFAM: helix-turn-helix domain protein YP_001229568.1 PFAM: CopG domain protein DNA-binding domain protein YP_001229569.1 PFAM: protein of unknown function DUF497 YP_001229570.1 PFAM: major facilitator superfamily MFS_1 YP_001229571.1 TIGRFAM: ribosome small subunit-dependent GTPase A; PFAM: GTPase EngC YP_001229574.1 PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain YP_001229575.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001229582.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase YP_001229583.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229584.1 PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa YP_001229586.1 TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001229587.1 PFAM: MscS Mechanosensitive ion channel YP_001229589.1 PFAM: Paraquat-inducible protein A YP_001229593.1 PFAM: Carbohydrate-selective porin OprB YP_001229595.1 PFAM: outer membrane efflux protein YP_001229596.1 PFAM: acriflavin resistance protein YP_001229597.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001229598.1 PFAM: regulatory protein, TetR YP_001229599.1 TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase YP_001229600.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein YP_001229601.1 PFAM: protein of unknown function DUF116 YP_001229602.1 PFAM: polysaccharide deacetylase YP_001229603.1 TIGRFAM: cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001229607.1 TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein; SMART: DEAD-like helicases-like YP_001229608.1 TIGRFAM: CRISPR-associated protein, Cse1 family YP_001229610.1 TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein, CT1974 YP_001229611.1 TIGRFAM: CRISPR-associated protein, Cse4 family YP_001229612.1 TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5 YP_001229613.1 PFAM: PemK family protein YP_001229614.1 PFAM: CopG domain protein DNA-binding domain protein YP_001229615.1 PFAM: S23 ribosomal protein YP_001229616.1 TIGRFAM: CRISPR-associated protein Cas1 YP_001229617.1 PFAM: transposase, IS4 family protein YP_001229618.1 TIGRFAM: CRISPR-associated protein Cas2 YP_001229621.1 TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region YP_001229622.1 TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase, central region YP_001229623.1 PFAM: protein of unknown function UPF0150; HicB family protein YP_001229625.1 PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain YP_001229628.1 PFAM: 3-demethylubiquinone-9 3-methyltransferase YP_001229629.1 PFAM: putative transposase YP_001229630.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp YP_001229631.1 PFAM: protein of unknown function DUF523 YP_001229632.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001229633.1 PFAM: response regulator receiver YP_001229634.1 PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II YP_001229635.1 PFAM: glycoside hydrolase, family 57 YP_001229636.1 TIGRFAM: galactose-1-phosphate uridylyltransferase YP_001229637.1 TIGRFAM: glycogen/starch synthase, ADP-glucose type; PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein YP_001229642.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229643.1 PFAM: Polysulphide reductase, NrfD YP_001229645.1 PFAM: aminotransferase, class V YP_001229648.1 PFAM: Rubredoxin-type Fe(Cys)4 protein YP_001229649.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP YP_001229650.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001229651.1 TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein YP_001229652.1 PFAM: nickel-dependent hydrogenase, large subunit YP_001229653.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561 YP_001229654.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001229655.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001229657.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001229658.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001229660.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001229661.1 PFAM: protein of unknown function DUF152 YP_001229665.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001229667.1 PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa; NADH dehydrogenase (ubiquinone), 30 kDa subunit YP_001229668.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001229671.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001229672.1 TIGRFAM: DNA binding domain, excisionase family; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_001229673.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001229674.1 PFAM: protein of unknown function DUF214 YP_001229677.1 PFAM: CopG domain protein DNA-binding domain protein YP_001229678.1 PFAM: Integral membrane protein TerC YP_001229680.1 PFAM: import inner membrane translocase, subunit Tim44 YP_001229681.1 PFAM: protein of unknown function UPF0182 YP_001229684.1 TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related YP_001229685.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001229686.1 PFAM: GAF domain protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001229690.1 PFAM: response regulator receiver YP_001229691.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region YP_001229692.1 PFAM: Silent information regulator protein Sir2 YP_001229693.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase, DuS; dihydroorotate dehydrogenase YP_001229694.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001229695.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001229696.1 PFAM: isochorismatase hydrolase YP_001229697.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001229698.1 PFAM: PKD domain containing protein YP_001229702.1 PFAM: NHL repeat containing protein YP_001229704.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001229705.1 PFAM: response regulator receiver; type IV pilus assembly PilZ YP_001229707.1 TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase, N-terminal domain protein; DnaB domain protein helicase, C-terminal domain protein YP_001229708.1 TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O, RecO YP_001229711.1 PFAM: dihydrofolate reductase region YP_001229712.1 PFAM: amine oxidase; FAD dependent oxidoreductase YP_001229713.1 TIGRFAM: cytochrome C family protein YP_001229714.1 TIGRFAM: MutS2 family protein; PFAM: DNA mismatch repair protein MutS domain protein; Smr protein/MutS2; SMART: MutS III domain protein YP_001229716.1 PFAM: phospholipase D/Transphosphatidylase YP_001229718.1 PFAM: nitrogen-fixing NifU domain protein YP_001229719.1 catalyzes the formation of fumarate from aspartate YP_001229720.1 PFAM: Rubrerythrin YP_001229721.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001229722.1 PFAM: protein of unknown function DUF185 YP_001229723.1 PFAM: Helix-turn-helix, type 11 domain protein YP_001229724.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001229725.1 PFAM: PilT protein domain protein YP_001229729.1 PFAM: protein of unknown function DUF1568 YP_001229730.1 PFAM: peptidase S10, serine carboxypeptidase; Pyridoxal-dependent decarboxylase YP_001229733.1 PFAM: peptidase M23B YP_001229734.1 TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; PFAM: putative methyltransferase YP_001229735.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal YP_001229736.1 PFAM: CheW domain protein YP_001229737.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001229739.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001229742.1 PFAM: CheD family protein YP_001229743.1 PFAM: dienelactone hydrolase YP_001229744.1 PFAM: phosphoribosyltransferase YP_001229745.1 PFAM: peptidase S9B, dipeptidylpeptidase IV domain protein; WD40 domain protein beta Propeller YP_001229746.1 PFAM: Rhomboid family protein YP_001229747.1 PFAM: phosphoesterase, PA-phosphatase related YP_001229748.1 PFAM: response regulator receiver YP_001229749.1 TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase, central region YP_001229750.1 PFAM: tRNA pseudouridine synthase D, TruD YP_001229752.1 PFAM: Na+/solute symporter YP_001229753.1 PFAM: protein of unknown function DUF294, nucleotidyltransferase putative YP_001229754.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001229755.1 PFAM: polysaccharide deacetylase YP_001229757.1 PFAM: response regulator receiver; General secretory system II, protein E domain protein YP_001229758.1 TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001229759.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001229760.1 PFAM: Saccharopine dehydrogenase YP_001229761.1 TIGRFAM: carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2 YP_001229762.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001229763.1 PFAM: major facilitator superfamily MFS_1 YP_001229764.1 PFAM: Hpt domain protein YP_001229765.1 PFAM: regulatory protein, TetR YP_001229772.1 TIGRFAM: cytochrome C family protein YP_001229776.1 PFAM: molybdopterin binding domain YP_001229777.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; ferredoxin; [2Fe-2S]-binding domain protein; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001229778.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein YP_001229780.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001229782.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001229784.1 PFAM: protein of unknown function DUF182 YP_001229785.1 PFAM: metal-dependent phosphohydrolase, HD sub domain YP_001229786.1 PFAM: Phosphoglycerate mutase YP_001229788.1 PFAM: protein of unknown function DUF497 YP_001229790.1 PFAM: protein of unknown function DUF1016 YP_001229795.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955 YP_001229796.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001229797.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001229798.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; NmrA family protein; Male sterility C-terminal domain YP_001229799.1 TIGRFAM: squalene/oxidosqualene cyclase; squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase YP_001229801.1 PFAM: putative rRNA methylase YP_001229802.1 PFAM: protein of unknown function DUF399 YP_001229803.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001229804.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like YP_001229805.1 PFAM: N-6 DNA methylase YP_001229806.1 PFAM: restriction modification system DNA specificity domain YP_001229811.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001229812.1 PFAM: aldehyde dehydrogenase YP_001229816.1 PFAM: General secretory system II, protein E domain protein YP_001229817.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_001229818.1 PFAM: protein of unknown function DUF140 YP_001229819.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001229820.1 PFAM: Mammalian cell entry related domain protein YP_001229821.1 PFAM: outer membrane efflux protein YP_001229822.1 PFAM: toluene tolerance family protein YP_001229823.1 TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A YP_001229824.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001229825.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001229826.1 TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region YP_001229827.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001229828.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001229829.1 forms a direct contact with the tRNA during translation YP_001229830.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001229831.1 PFAM: Radical SAM domain protein; Radical SAM N-terminal domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001229832.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001229833.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif YP_001229834.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001229835.1 TIGRFAM: transcription termination/antitermination factor NusG; PFAM: transcription antitermination protein NusG; KOW domain protein; SMART: NGN domain protein; KOW (Kyrpides, Ouzounis, Woese) domain protein YP_001229836.1 binds directly to 23S ribosomal RNA YP_001229837.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001229838.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001229839.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001229840.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001229841.1 TIGRFAM: DNA-directed RNA polymerase, beta' subunit; PFAM: RNA polymerase, alpha subunit; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 5; RNA polymerase Rpb1, domain 4; SMART: RNA polymerase I subunit A domain protein YP_001229842.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001229843.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001229844.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001229845.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001229846.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001229847.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001229848.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001229849.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001229850.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001229851.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001229852.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001229853.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001229854.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001229855.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001229856.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001229857.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001229858.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif YP_001229859.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001229860.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001229861.1 binds 5S rRNA along with protein L5 and L25 YP_001229862.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001229863.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001229864.1 late assembly protein YP_001229865.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001229866.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001229867.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24 YP_001229868.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001229869.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001229870.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001229871.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001229872.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001229873.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein YP_001229874.1 PFAM: Roadblock/LC7 family protein YP_001229875.1 TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54, G- domain; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_001229878.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase YP_001229879.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP YP_001229880.1 PFAM: metallophosphoesterase YP_001229881.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001229884.1 PFAM: Integrase, catalytic region YP_001229885.1 SMART: AAA ATPase YP_001229889.1 PFAM: transcriptional activator domain YP_001229891.1 SMART: LamG domain protein jellyroll fold domain protein YP_001229899.1 PFAM: sugar fermentation stimulation protein YP_001229900.1 PFAM: nickel-dependent hydrogenase, large subunit YP_001229901.1 PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001229902.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001229903.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229904.1 PFAM: outer membrane efflux protein YP_001229905.1 PFAM: protein of unknown function DUF214 YP_001229906.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001229907.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001229908.1 PFAM: regulatory protein, MarR YP_001229909.1 PFAM: phosphoesterase, PA-phosphatase related YP_001229910.1 PFAM: UMUC domain protein DNA-repair protein YP_001229911.1 PFAM: DNA polymerase, beta domain protein region YP_001229912.1 TIGRFAM: nucleotidyltransferase substrate binding protein, HI0074 family; PFAM: Nucleotidyltransferase substrate binding protein, HI0074 YP_001229913.1 PFAM: helix-turn-helix domain protein YP_001229915.1 PFAM: PilT protein domain protein YP_001229916.1 SMART: Nucleotide binding protein, PINc YP_001229917.1 TIGRFAM: prevent-host-death family protein YP_001229919.1 TIGRFAM: LexA repressor; PFAM: peptidase S24, S26A and S26B; LexA DNA-binding domain protein YP_001229920.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region YP_001229921.1 PFAM: Integral membrane protein TerC YP_001229922.1 PFAM: peptidase M48, Ste24p YP_001229923.1 PFAM: response regulator receiver; ANTAR domain protein YP_001229924.1 PFAM: secretion protein HlyD family protein YP_001229925.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001229926.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001229927.1 PFAM: ABC-2 type transporter YP_001229928.1 PFAM: ABC-2 type transporter YP_001229929.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; type IV pilus assembly PilZ; SMART: AAA ATPase YP_001229932.1 PFAM: peptidase C39, bacteriocin processing YP_001229935.1 TIGRFAM: YD repeat protein; PFAM: YD repeat-containing protein; FG-GAP repeat protein YP_001229936.1 PFAM: OmpW family protein YP_001229942.1 PFAM: protein of unknown function YGGT YP_001229943.1 PFAM: DivIVA family protein YP_001229944.1 PFAM: protein of unknown function DUF167 YP_001229945.1 TIGRFAM: putative regulatory protein, FmdB family YP_001229946.1 PFAM: tetrahydrofolate dehydrogenase/cyclohydrolase YP_001229948.1 PFAM: methylenetetrahydrofolate reductase YP_001229949.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase YP_001229950.1 TIGRFAM: TonB family protein YP_001229951.1 PFAM: protein of unknown function UPF0016 YP_001229952.1 TIGRFAM: nitrogenase iron protein; PFAM: NifH/frxC-family protein YP_001229953.1 TIGRFAM: nitrogenase molybdenum-iron protein alpha chain; nitrogenase component I, alpha chain; PFAM: oxidoreductase/nitrogenase, component 1 YP_001229954.1 TIGRFAM: nitrogenase molybdenum-iron protein beta chain; PFAM: oxidoreductase/nitrogenase, component 1 YP_001229959.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001229960.1 PFAM: secretion protein HlyD family protein YP_001229961.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001229962.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001229963.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001229964.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001229965.1 PFAM: protein of unknown function DUF559 YP_001229966.1 PFAM: extracellular solute-binding protein, family 5 YP_001229967.1 PFAM: regulatory protein, TetR YP_001229968.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; SMART: PAS domain containing protein YP_001229969.1 PFAM: beta-Ig-H3/fasciclin YP_001229970.1 PFAM: UBA/THIF-type NAD/FAD binding protein YP_001229971.1 PFAM: thiamineS protein YP_001229972.1 PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase-like YP_001229973.1 PFAM: iron-containing alcohol dehydrogenase YP_001229974.1 PFAM: isochorismatase hydrolase YP_001229975.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001229976.1 PFAM: HEPN domain protein YP_001229977.1 PFAM: DNA polymerase, beta domain protein region YP_001229978.1 in some organisms the NifE and NifN proteins are encoded separately; functions in assembly of FeMo cofactor; functions in assembly of nitrogenase MoFe YP_001229979.1 TIGRFAM: nitrogen fixation protein NifX; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein YP_001229980.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229981.1 PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein YP_001229982.1 PFAM: Dinitrogenase reductase ADP-ribosyltransferase YP_001229985.1 TIGRFAM: ADP-ribosyl-[dinitrogen reductase] hydrolase; PFAM: ADP-ribosylation/Crystallin J1 YP_001229986.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001229987.1 PFAM: GCN5-related N-acetyltransferase YP_001229988.1 PFAM: electron transfer flavoprotein beta-subunit YP_001229989.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit; 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001229990.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein YP_001229991.1 PFAM: glutamine amidotransferase class-I YP_001229992.1 PFAM: plasmid maintenance system killer YP_001229993.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein YP_001229994.1 PFAM: helix-turn-helix- domain containing protein, AraC type; transcription activator, effector binding YP_001229995.1 PFAM: CopG domain protein DNA-binding domain protein; protein of unknown function UPF0150 YP_001229996.1 PFAM: glycosyl hydrolase, BNR repeat-containing protein; metallophosphoesterase YP_001229997.1 PFAM: ribonuclease H; 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2 YP_001229998.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001229999.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001230000.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001230001.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Osmosensitive K+ channel His kinase sensor; UspA domain protein YP_001230002.1 TIGRFAM: potassium-transporting ATPase, C subunit; PFAM: K+ transporting ATPase, KdpC subunit YP_001230003.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; K+-transporting ATPase, B subunit; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein YP_001230004.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001230005.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Contains selenocysteine YP_001230006.1 PFAM: DTW domain containing protein YP_001230009.1 PFAM: Integrase, catalytic region YP_001230014.1 TIGRFAM: YD repeat protein YP_001230015.1 PFAM: Integrase, catalytic region YP_001230017.1 TIGRFAM: YD repeat protein YP_001230018.1 PFAM: nitroreductase YP_001230020.1 PFAM: Mammalian cell entry related domain protein YP_001230021.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001230022.1 PFAM: protein of unknown function DUF140 YP_001230023.1 TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001230024.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001230025.1 PFAM: plasmid stabilization system YP_001230027.1 PFAM: HNH endonuclease YP_001230029.1 PFAM: Post-segregation antitoxin CcdA YP_001230030.1 PFAM: RNP-1 like RNA-binding protein YP_001230031.1 PFAM: DTW domain containing protein YP_001230033.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein YP_001230035.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001230036.1 PFAM: protein of unknown function DUF190 YP_001230037.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001230038.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001230039.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172 YP_001230040.1 PFAM: plasmid stabilization system YP_001230041.1 TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase YP_001230042.1 Catalyzes the conversion of citrate to isocitrate YP_001230043.1 PFAM: dehydrogenase, E1 component YP_001230044.1 PFAM: Transketolase, central region; Transketolase domain protein YP_001230045.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001230046.1 TIGRFAM: lipoate-protein ligase B; PFAM: biotin/lipoate A/B protein ligase YP_001230047.1 PFAM: peptidase S16, lon domain protein YP_001230048.1 PFAM: NAD(P)H dehydrogenase (quinone) YP_001230050.1 PFAM: DSBA oxidoreductase YP_001230051.1 PFAM: isochorismatase hydrolase YP_001230053.1 PFAM: DNA polymerase, beta domain protein region YP_001230055.1 PFAM: filamentation induced by cAMP protein Fic YP_001230056.1 PFAM: sigma-54 factor, interaction domain-containing protein; GAF domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001230057.1 PFAM: glycosyl transferase, family 2 YP_001230058.1 PFAM: response regulator receiver; CheW domain protein YP_001230059.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001230060.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; Cache domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001230061.1 PFAM: Chromate transporter YP_001230062.1 PFAM: Chromate transporter YP_001230065.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001230066.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001230067.1 PFAM: protein of unknown function DUF214 YP_001230068.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001230069.1 PFAM: secretion protein HlyD family protein YP_001230070.1 PFAM: protein of unknown function DUF1622 YP_001230071.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001230072.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001230074.1 SMART: helix-turn-helix domain protein YP_001230076.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001230078.1 catalyzes the hydrolysis of acylphosphate YP_001230079.1 TIGRFAM: DNA ligase, NAD-dependent; PFAM: BRCT domain protein; zinc-finger, NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase, OB-fold; NAD-dependent DNA ligase, adenylation; SMART: Helix-hairpin-helix DNA-binding, class 1; NAD-dependent DNA ligase-like YP_001230080.1 PFAM: extracellular solute-binding protein, family 1 YP_001230081.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001230082.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001230086.1 PFAM: extracellular solute-binding protein, family 3; ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001230087.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001230088.1 PFAM: glycosyl transferase, group 1 YP_001230090.1 PFAM: Di-haem cytochrome c peroxidase YP_001230092.1 PFAM: plasmid stabilization system YP_001230093.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172 YP_001230095.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001230097.1 PFAM: glycosyl transferase, family 2 YP_001230098.1 TIGRFAM: hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain protein YP_001230099.1 PFAM: UvrD/REP helicase YP_001230100.1 PFAM: response regulator receiver YP_001230102.1 PFAM: helix-turn-helix domain protein YP_001230104.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001230105.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001230106.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001230107.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001230108.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001230109.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001230110.1 PFAM: regulatory protein, MerR YP_001230111.1 PFAM: acetyl-CoA hydrolase/transferase YP_001230112.1 SMART: regulatory protein, IclR YP_001230113.1 PFAM: protein of unknown function DUF485 YP_001230114.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter YP_001230116.1 TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: ArgK protein; methylmalonyl-CoA mutase; cobalamin B12-binding domain protein YP_001230117.1 PFAM: thioesterase superfamily protein YP_001230118.1 PFAM: nitroreductase YP_001230119.1 PFAM: creatinase; peptidase M24 YP_001230120.1 PFAM: asparagine synthase YP_001230121.1 PFAM: GCN5-related N-acetyltransferase YP_001230122.1 PFAM: phage Tail Collar domain protein YP_001230123.1 PFAM: phage Tail Collar domain protein YP_001230124.1 PFAM: phage Tail Collar domain protein YP_001230125.1 PFAM: asparagine synthase YP_001230128.1 PFAM: sulfotransferase YP_001230131.1 PFAM: protein of unknown function DUF6, transmembrane YP_001230132.1 SMART: helix-turn-helix domain protein YP_001230133.1 PFAM: protein of unknown function DUF891 YP_001230138.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001230139.1 PFAM: Tellurite resistance protein TehB; Methyltransferase type 11; Methyltransferase type 12 YP_001230140.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001230141.1 PFAM: protein of unknown function DUF147; YbbR family protein YP_001230142.1 PFAM: NLP/P60 protein; Peptidoglycan-binding LysM YP_001230143.1 PFAM: TPR repeat-containing protein; cobalamin B12-binding domain protein; Radical SAM domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Elongator protein 3/MiaB/NifB; Tetratricopeptide domain protein YP_001230145.1 PFAM: AsmA family protein YP_001230146.1 PFAM: response regulator receiver YP_001230148.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001230149.1 PFAM: sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001230150.1 PFAM: regulatory protein, MarR YP_001230152.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase YP_001230153.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001230154.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001230155.1 TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase; SMART: AAA ATPase YP_001230156.1 PFAM: Arsenical resistance operon trans-acting repressor ArsD YP_001230158.1 PFAM: cytochrome c biogenesis protein, transmembrane region YP_001230160.1 PFAM: amino acid permease-associated region YP_001230161.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001230162.1 PFAM: ABC-1 domain protein YP_001230165.1 PFAM: protein of unknown function DUF208 YP_001230166.1 PFAM: protein of unknown function DUF101 YP_001230167.1 PFAM: protein of unknown function UPF0027 YP_001230168.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001230170.1 PFAM: protein of unknown function DUF497 YP_001230171.1 PFAM: NLP/P60 protein YP_001230172.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001230173.1 PFAM: creatinase; peptidase M24 YP_001230174.1 PFAM: regulatory protein, MerR YP_001230178.1 PFAM: PilT protein domain protein YP_001230179.1 TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein YP_001230186.1 PFAM: Chromosomal replication initiator, DnaA YP_001230187.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001230188.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001230189.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001230190.1 PFAM: protein of unknown function DUF28 YP_001230192.1 PFAM: regulatory protein, IclR YP_001230193.1 PFAM: protein of unknown function DUF485 YP_001230194.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter YP_001230195.1 PFAM: protein of unknown function DUF294, nucleotidyltransferase putative YP_001230196.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; Cache, type 2 domain protein YP_001230197.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172 YP_001230198.1 PFAM: plasmid stabilization system YP_001230202.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001230206.1 PFAM: protein of unknown function DUF81 YP_001230210.1 PFAM: SlyX family protein YP_001230211.1 PFAM: aldo/keto reductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001230216.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172 YP_001230217.1 TIGRFAM: addiction module toxin, Txe/YoeB family; addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; Addiction module toxin, Txe/YoeB YP_001230219.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001230220.1 PFAM: Porphyromonas-type peptidyl-arginine deiminase YP_001230221.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP YP_001230222.1 PFAM: Sel1 domain protein repeat-containing protein YP_001230224.1 PFAM: protein of unknown function DUF503 YP_001230225.1 PFAM: manganese and iron superoxide dismutase YP_001230226.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein YP_001230228.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001230229.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001230230.1 PFAM: protein of unknown function DUF214 YP_001230231.1 PFAM: protein of unknown function DUF214 YP_001230234.1 PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein YP_001230235.1 PFAM: Prephenate dehydrogenase YP_001230236.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001230237.1 TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region YP_001230238.1 TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein YP_001230239.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001230240.1 PFAM: histone family protein DNA-binding protein YP_001230243.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001230244.1 TIGRFAM: YD repeat protein YP_001230247.1 PFAM: regulator of chromosome condensation, RCC1 YP_001230248.1 PFAM: helix-turn-helix domain protein YP_001230249.1 PFAM: HipA domain protein YP_001230250.1 PFAM: SpoVT/AbrB domain protein YP_001230252.1 PFAM: N-6 DNA methylase YP_001230254.1 PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like YP_001230255.1 PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase YP_001230257.1 PFAM: protein of unknown function UPF0153 YP_001230259.1 PFAM: plasmid stabilization system YP_001230260.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172 YP_001230262.1 TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: deoxyribonuclease/rho motif-related TRAM; Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB YP_001230263.1 PFAM: transposase, IS4 family protein YP_001230264.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001230265.1 PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001230266.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074 YP_001230267.1 TIGRFAM: serine O-acetyltransferase YP_001230268.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001230270.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001230271.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001230272.1 TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001230273.1 PFAM: protein of unknown function DUF155 YP_001230277.1 PFAM: phosphatidylserine decarboxylase-related YP_001230279.1 TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001230280.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001230281.1 TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001230282.1 PFAM: EAL domain protein YP_001230285.1 PFAM: CBS domain containing protein; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein YP_001230286.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein YP_001230287.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001230288.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component YP_001230289.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component YP_001230290.1 TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001230292.1 PFAM: protein of unknown function DUF502 YP_001230294.1 PFAM: GCN5-related N-acetyltransferase YP_001230295.1 PFAM: YbaK/prolyl-tRNA synthetase associated region YP_001230297.1 PFAM: adenylate cyclase YP_001230298.1 PFAM: protein of unknown function DUF169 YP_001230300.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001230301.1 TIGRFAM: lipoprotein signal peptidase; PFAM: peptidase A8, signal peptidase II YP_001230302.1 PFAM: protein of unknown function DUF156 YP_001230303.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein YP_001230304.1 PFAM: alpha/beta hydrolase fold YP_001230305.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain YP_001230307.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001230309.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001230310.1 TIGRFAM: putative CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type YP_001230311.1 PFAM: transposase IS3/IS911 family protein YP_001230312.1 PFAM: Integrase, catalytic region YP_001230314.1 PFAM: ATP-binding region, ATPase domain protein YP_001230315.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001230316.1 PFAM: transposase, IS4 family protein YP_001230318.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001230319.1 PFAM: response regulator receiver YP_001230320.1 TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001230321.1 TIGRFAM: PAS sensor protein; PFAM: histidine kinase, HAMP region domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001230323.1 PFAM: TonB-dependent receptor, plug YP_001230324.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001230325.1 PFAM: regulatory protein, MarR YP_001230328.1 PFAM: Rhodanese domain protein YP_001230329.1 PFAM: Rhodanese domain protein YP_001230331.1 PFAM: protein of unknown function DUF224, cysteine-rich region domain protein YP_001230332.1 PFAM: glycosyl transferase, family 2 YP_001230333.1 PFAM: Rhodanese domain protein YP_001230335.1 PFAM: Radical SAM domain protein YP_001230336.1 PFAM: glycosyl transferase, family 2 YP_001230338.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001230339.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_001230340.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001230341.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001230342.1 activates fatty acids by binding to coenzyme A YP_001230344.1 PFAM: creatinase; peptidase M24 YP_001230345.1 PFAM: Citrate synthase YP_001230346.1 PFAM: AMMECR1 domain protein YP_001230347.1 PFAM: aldehyde dehydrogenase YP_001230349.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001230350.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001230351.1 TIGRFAM: methylthioadenosine phosphorylase; PFAM: purine phosphorylase, family 2 YP_001230352.1 PFAM: protein of unknown function DUF815 YP_001230357.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation YP_001230359.1 PFAM: AMP-dependent synthetase and ligase YP_001230360.1 PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001230361.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001230362.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001230363.1 PFAM: beta-lactamase domain protein YP_001230364.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001230366.1 PFAM: alpha/beta hydrolase fold YP_001230367.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001230368.1 PFAM: regulatory protein, MerR YP_001230369.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein YP_001230370.1 PFAM: electron transfer flavoprotein beta-subunit YP_001230371.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit YP_001230372.1 PFAM: electron transfer flavoprotein beta-subunit; protein of unknown function DUF224, cysteine-rich region domain protein YP_001230373.1 PFAM: GTP-binding protein, HSR1-related YP_001230374.1 PFAM: pseudouridine synthase YP_001230375.1 PFAM: protein of unknown function RIO1 YP_001230376.1 TIGRFAM: alanine dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; alanine dehydrogenase/PNT domain protein YP_001230377.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001230378.1 PFAM: dehydrogenase, E1 component YP_001230379.1 PFAM: Transketolase, central region; Transketolase domain protein YP_001230380.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001230384.1 PFAM: RNP-1 like RNA-binding protein YP_001230385.1 TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_001230387.1 PFAM: Abortive infection protein YP_001230388.1 PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain YP_001230390.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase YP_001230391.1 PFAM: Integrase, catalytic region YP_001230392.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein YP_001230393.1 PFAM: sulfatase YP_001230394.1 PFAM: diacylglycerol kinase, catalytic region YP_001230399.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein YP_001230400.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001230401.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001230402.1 PFAM: pentapeptide repeat protein YP_001230403.1 PFAM: protein of unknown function DUF500 YP_001230404.1 PFAM: peptidase M1, membrane alanine aminopeptidase YP_001230405.1 PFAM: Rhomboid family protein YP_001230408.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001230409.1 PFAM: response regulator receiver YP_001230411.1 PFAM: protein of unknown function DUF6, transmembrane YP_001230412.1 PFAM: protein of unknown function DUF815 YP_001230416.1 PFAM: PEBP family protein YP_001230418.1 PFAM: regulatory protein, TetR YP_001230419.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region YP_001230422.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; Male sterility C-terminal domain YP_001230423.1 PFAM: regulatory protein, TetR YP_001230424.1 PFAM: ABC-1 domain protein YP_001230425.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001230426.1 PFAM: protein of unknown function DUF214 YP_001230432.1 PFAM: PHP C-terminal domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; Helix-hairpin-helix DNA-binding, class 1 YP_001230433.1 PFAM: RNA 3'-terminal phosphate cyclase; RNA 3'-terminal phosphate cyclase, insert region YP_001230437.1 PFAM: polysaccharide export protein YP_001230438.1 PFAM: lipopolysaccharide biosynthesis protein YP_001230440.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001230441.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase, NAD-binding YP_001230442.1 PFAM: ABC-2 type transporter YP_001230443.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001230445.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain YP_001230446.1 PFAM: Methyltransferase type 11 YP_001230447.1 PFAM: glycosyl transferase, family 11 YP_001230450.1 PFAM: glycosyl transferase, family 2 YP_001230451.1 PFAM: glycosyl transferase, group 1 YP_001230452.1 PFAM: glycosyl transferase, group 1 YP_001230453.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain YP_001230454.1 PFAM: glycosyl transferase, group 1 YP_001230455.1 TIGRFAM: methyltransferase FkbM family YP_001230456.1 PFAM: glycosyl transferase, group 1 YP_001230457.1 PFAM: glycosyl transferase, group 1 YP_001230459.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001230460.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamide and glutamine to imidazole-glycerolphosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001230461.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain YP_001230464.1 PFAM: UDP-N-acetylglucosamine 2-epimerase YP_001230465.1 PFAM: glycosyl transferase, group 1 YP_001230466.1 PFAM: sugar transferase YP_001230469.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001230470.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; CoA-binding domain protein; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KR YP_001230471.1 TIGRFAM: 6-phosphofructokinase; PFAM: phosphofructokinase YP_001230472.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_001230473.1 TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase, family 35 YP_001230474.1 PFAM: ATP-NAD/AcoX kinase YP_001230475.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein YP_001230476.1 catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate YP_001230477.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001230478.1 PFAM: regulatory protein, ArsR YP_001230479.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001230480.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001230481.1 TIGRFAM: metal dependent phophohydrolase; PFAM: GAF domain protein; histidine kinase, HAMP region domain protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001230482.1 TIGRFAM: SpoIID/LytB domain; PFAM: Stage II sporulation D domain protein YP_001230483.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001230484.1 TIGRFAM: tRNA-guanine transglycosylase, various specificities; queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase YP_001230485.1 TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein YP_001230486.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001230487.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001230488.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001230489.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1 YP_001230490.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001230492.1 PFAM: DNA polymerase, beta domain protein region YP_001230493.1 PFAM: HEPN domain protein YP_001230495.1 molecular chaperone YP_001230496.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; Cache domain protein; histidine kinase, dimerisation/phosphoacceptor; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001230497.1 PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001230498.1 TIGRFAM: anthranilate synthase component I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein YP_001230499.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001230500.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001230501.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001230502.1 catalyzes the formation of L-tryptophan from indole and L-serine YP_001230503.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_001230504.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001230505.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001230506.1 PFAM: isochorismatase hydrolase YP_001230509.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001230511.1 PFAM: lipolytic enzyme, G-D-S-L family YP_001230514.1 PFAM: DNA polymerase, beta domain protein region YP_001230515.1 TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A YP_001230517.1 PFAM: PilT protein domain protein YP_001230520.1 TIGRFAM: metal dependent phophohydrolase; PFAM: GAF domain protein; histidine kinase, HAMP region domain protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001230522.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_001230523.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001230524.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase YP_001230525.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001230531.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001230533.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001230534.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001230535.1 TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein, core YP_001230536.1 PFAM: protein of unknown function UPF0118 YP_001230537.1 PFAM: protein of unknown function DUF512 YP_001230538.1 PFAM: protein of unknown function DUF399 YP_001230540.1 PFAM: transposase, IS4 family protein YP_001230541.1 TIGRFAM: transcription elongation factor GreB; PFAM: transcription elongation factor GreA/GreB domain protein YP_001230543.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001230544.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; metal-dependent phosphohydrolase, 7TM intracellular region; SMART: metal-dependent phosphohydrolase, HD region YP_001230545.1 PFAM: protein of unknown function UPF0054 YP_001230546.1 PFAM: phosphoesterase, PA-phosphatase related; diacylglycerol kinase YP_001230547.1 PFAM: CBS domain containing protein; transporter-associated region YP_001230548.1 Transfers the fatty acyl group on membrane lipoproteins YP_001230549.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein YP_001230550.1 PFAM: NLP/P60 protein; Sporulation domain protein YP_001230552.1 PFAM: uncharacterised conserved protein UCP033563 YP_001230553.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001230555.1 PFAM: regulator of chromosome condensation, RCC1 YP_001230556.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001230557.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001230558.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001230560.1 PFAM: beta-lactamase YP_001230561.1 PFAM: response regulator receiver YP_001230562.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001230563.1 PFAM: peptidase A24A, prepilin type IV; peptidase A24A domain protein YP_001230564.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001230565.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001230572.1 PFAM: helix-turn-helix domain protein YP_001230573.1 TIGRFAM: type IV pilus assembly protein PilM YP_001230574.1 PFAM: Fimbrial assembly family protein YP_001230575.1 PFAM: Pilus assembly protein, PilO YP_001230577.1 TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB, short N-terminal domain YP_001230579.1 PFAM: Ig family protein YP_001230581.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001230582.1 PFAM: shikimate kinase YP_001230583.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001230584.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001230586.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001230587.1 PFAM: creatinase; peptidase M24 YP_001230588.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein YP_001230589.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp YP_001230590.1 TIGRFAM: glycine cleavage system H protein; PFAM: glycine cleavage H-protein YP_001230591.1 PFAM: protein of unknown function DUF178 YP_001230592.1 PFAM: NUDIX hydrolase YP_001230594.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III YP_001230595.1 TIGRFAM: Fe-S cluster assembly protein NifU; PFAM: nitrogen-fixing NifU domain protein; BFD domain protein [2Fe-2S]-binding domain protein YP_001230596.1 PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001230597.1 TIGRFAM: cytochrome C family protein YP_001230599.1 PFAM: NHL repeat containing protein YP_001230600.1 TIGRFAM: cytochrome C family protein YP_001230603.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001230604.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001230605.1 TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein YP_001230606.1 PFAM: SEFIR domain protein YP_001230608.1 PFAM: UvrD/REP helicase YP_001230611.1 PFAM: Integrase, catalytic region YP_001230613.1 PFAM: transposase, IS4 family protein YP_001230618.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_001230619.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001230620.1 TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; Amidohydrolase 3 YP_001230621.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001230622.1 PFAM: Radical SAM domain protein YP_001230623.1 PFAM: protein of unknown function DUF486 YP_001230624.1 PFAM: DNA polymerase, beta domain protein region YP_001230625.1 PFAM: protein of unknown function DUF86 YP_001230626.1 PFAM: SEC-C motif domain protein YP_001230627.1 TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp YP_001230628.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001230630.1 PFAM: SpoVT/AbrB domain protein YP_001230631.1 PFAM: PilT protein domain protein; SMART: Nucleotide binding protein, PINc YP_001230632.1 catalyzes branch migration in Holliday junction intermediates YP_001230633.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001230634.1 TIGRFAM: putative delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase; Proline dehydrogenase YP_001230635.1 PFAM: protein of unknown function DUF177 YP_001230636.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001230637.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001230638.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III YP_001230639.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein YP_001230640.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001230641.1 carries the fatty acid chain in fatty acid biosynthesis YP_001230642.1 PFAM: beta-ketoacyl synthase YP_001230643.1 TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase YP_001230644.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001230648.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein YP_001230649.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver YP_001230650.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001230651.1 PFAM: protein of unknown function DUF610, YibQ YP_001230653.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001230654.1 PFAM: Haloacid dehalogenase domain protein hydrolase YP_001230655.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001230656.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001230657.1 PFAM: Mammalian cell entry related domain protein YP_001230659.1 PFAM: protein of unknown function DUF140 YP_001230660.1 PFAM: beta-lactamase domain protein YP_001230661.1 PFAM: protein of unknown function DUF150 YP_001230662.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001230663.1 PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; protein of unknown function DUF448 YP_001230664.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001230665.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001230666.1 PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1 YP_001230667.1 TIGRFAM: tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein YP_001230668.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001230669.1 PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein YP_001230670.1 PFAM: peptidase M16 domain protein YP_001230671.1 catalyzes the formation of dUMP from dUTP YP_001230672.1 PFAM: peptidase M29, aminopeptidase II YP_001230673.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain YP_001230675.1 PFAM: Patatin YP_001230677.1 TIGRFAM: trigger factor; PFAM: peptidylprolyl isomerase, FKBP-type; trigger factor, C-terminal domain protein; trigger factor, N-terminal domain YP_001230678.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001230679.1 binds and unfolds substrates as part of the ClpXP protease YP_001230680.1 TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001230681.1 PFAM: histone family protein DNA-binding protein YP_001230682.1 PFAM: glycosyl transferase, family 2 YP_001230683.1 PFAM: NHL repeat containing protein YP_001230686.1 PFAM: type II secretion system protein YP_001230687.1 PFAM: type II secretion system protein E; General secretory system II, protein E domain protein YP_001230689.1 PFAM: Fimbrial assembly family protein YP_001230692.1 PFAM: TPR repeat-containing protein; cellulosome anchoring protein, cohesin region; type II and III secretion system protein; NolW domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001230694.1 PFAM: type II secretion system protein G YP_001230695.1 TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase YP_001230696.1 PFAM: protein of unknown function DUF214 YP_001230697.1 PFAM: peptidase M23B YP_001230698.1 TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001230700.1 PFAM: Ig domain protein, group 1 domain protein YP_001230702.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001230704.1 PFAM: GAF domain protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001230705.1 TIGRFAM: hydrogenase nickel insertion protein HypA; PFAM: hydrogenase expression/synthesis, HypA YP_001230706.1 TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein YP_001230707.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2 YP_001230708.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits YP_001230709.1 PFAM: nickel-dependent hydrogenase, large subunit YP_001230710.1 TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52, hydrogen uptake protein YP_001230711.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106 YP_001230712.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K YP_001230713.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein YP_001230714.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC) YP_001230715.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein YP_001230716.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein YP_001230717.1 PFAM: type IV pilus assembly PilZ YP_001230718.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001230720.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001230722.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001230723.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001230724.1 PFAM: Radical SAM domain protein YP_001230725.1 PFAM: Radical SAM domain protein YP_001230726.1 PFAM: polysaccharide biosynthesis protein YP_001230727.1 PFAM: TonB-dependent receptor, plug YP_001230730.1 PFAM: response regulator receiver YP_001230734.1 PFAM: PemK family protein YP_001230735.1 PFAM: ADP-ribosylation/Crystallin J1 YP_001230736.1 PFAM: GCN5-related N-acetyltransferase YP_001230737.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001230739.1 PFAM: peptidase M20; peptidase M28 YP_001230740.1 TIGRFAM: apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001230741.1 PFAM: transport-associated protein YP_001230742.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase YP_001230743.1 PFAM: SMC domain protein YP_001230744.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001230748.1 PFAM: Sel1 domain protein repeat-containing protein YP_001230749.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein YP_001230750.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001230753.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein YP_001230758.1 TIGRFAM: cytochrome C family protein YP_001230759.1 TIGRFAM: cytochrome C family protein YP_001230760.1 PFAM: NHL repeat containing protein YP_001230761.1 PFAM: Sel1 domain protein repeat-containing protein YP_001230763.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein YP_001230764.1 PFAM: carbonic anhydrase YP_001230766.1 PFAM: PemK family protein YP_001230769.1 PFAM: 4'-phosphopantetheinyl transferase YP_001230770.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain YP_001230771.1 Catalyzes the specific recognition and activation of amino acids during peptide synthesis YP_001230772.1 PFAM: alpha/beta hydrolase fold YP_001230773.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001230774.1 PFAM: beta-ketoacyl synthase; Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_001230775.1 PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; KR YP_001230776.1 PFAM: 2-nitropropane dioxygenase, NPD YP_001230777.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001230780.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001230781.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001230782.1 PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type YP_001230785.1 PFAM: Fibronectin, type III domain protein YP_001230786.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001230787.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease YP_001230788.1 TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP YP_001230789.1 PFAM: cobalamin B12-binding domain protein YP_001230790.1 TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; SMART: AAA ATPase YP_001230791.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein YP_001230793.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU) YP_001230795.1 PFAM: LemA family protein YP_001230796.1 PFAM: protein of unknown function DUF477 YP_001230797.1 PFAM: protein of unknown function DUF477 YP_001230798.1 TIGRFAM: cytochrome C family protein YP_001230799.1 PFAM: Fibronectin, type III domain protein YP_001230800.1 TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein YP_001230801.1 PFAM: histidine triad (HIT) protein YP_001230803.1 PFAM: natural resistance-associated macrophage protein YP_001230804.1 PFAM: CBS domain containing protein; MgtE intracellular region YP_001230805.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001230806.1 PFAM: ATP-binding region, ATPase domain protein YP_001230807.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS YP_001230808.1 PFAM: Na+/solute symporter; GAF domain protein; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein YP_001230811.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001230812.1 PFAM: extracellular solute-binding protein, family 5 YP_001230813.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001230814.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001230815.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001230817.1 PFAM: protein of unknown function DUF815 YP_001230818.1 TIGRFAM: oligoendopeptidase, pepF/M3 family; PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; Oligopeptidase F YP_001230820.1 PFAM: outer membrane lipoprotein Slp YP_001230821.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit YP_001230822.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001230823.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001230824.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001230825.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; PAS fold domain protein YP_001230826.1 PFAM: beta-lactamase domain protein YP_001230827.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001230828.1 PFAM: MscS Mechanosensitive ion channel YP_001230829.1 TIGRFAM: phosphoribosylformylglycinamidine synthase II; PFAM: AIR synthase related protein; AIR synthase related protein domain protein YP_001230831.1 TIGRFAM: amidophosphoribosyltransferase; PFAM: glutamine amidotransferase, class-II; phosphoribosyltransferase YP_001230832.1 TIGRFAM: orotate phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001230834.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein YP_001230836.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001230837.1 PFAM: histidine triad (HIT) protein YP_001230838.1 PFAM: ROK family protein YP_001230839.1 PFAM: phosphofructokinase YP_001230840.1 PFAM: GAF domain protein; chemotaxis sensory transducer YP_001230841.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001230842.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001230843.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001230844.1 PFAM: amidohydrolase; Amidohydrolase 3 YP_001230846.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001230849.1 PFAM: DNA polymerase, beta domain protein region YP_001230850.1 PFAM: protein of unknown function UPF0270 YP_001230853.1 PFAM: phage Gp37Gp68 family protein YP_001230855.1 PFAM: helix-turn-helix domain protein YP_001230856.1 PFAM: HipA domain protein YP_001230858.1 PFAM: putative RNA methylase; N-6 DNA methylase YP_001230860.1 PFAM: restriction modification system DNA specificity domain YP_001230861.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172 YP_001230862.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system YP_001230864.1 PFAM: DNA topoisomerase, type IA, zn finger domain protein YP_001230865.1 PFAM: protein of unknown function DUF167 YP_001230866.1 PFAM: nitroreductase YP_001230867.1 PFAM: protein of unknown function UPF0047 YP_001230872.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001230873.1 PFAM: DEAD_2 domain protein; SMART: DEXDc2; helicase c2; DEAD-like helicases-like YP_001230875.1 PFAM: peptidase S10, serine carboxypeptidase YP_001230876.1 PFAM: extracellular solute-binding protein, family 3; ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001230877.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001230878.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001230879.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, dimerisation/phosphoacceptor; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001230880.1 PFAM: domain of unknown function DUF1745 YP_001230881.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_001230882.1 PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein YP_001230883.1 PFAM: Radical SAM domain protein YP_001230884.1 PFAM: Creatininase YP_001230886.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001230887.1 PFAM: transposase IS200-family protein YP_001230888.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001230889.1 PFAM: inner-membrane translocator YP_001230890.1 PFAM: inner-membrane translocator YP_001230891.1 PFAM: Extracellular ligand-binding receptor YP_001230892.1 PFAM: Extracellular ligand-binding receptor YP_001230893.1 PFAM: amino acid-binding ACT domain protein YP_001230895.1 Involved in the incorporation of exogenous aryl acids in the biosynthesis of aromatic amino acids: catalysis of the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. YP_001230896.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate enzyme domain protein TPP-binding YP_001230898.1 PFAM: Ppx/GppA phosphatase YP_001230899.1 PFAM: Na+/Pi-cotransporter YP_001230902.1 PFAM: OmpA/MotB domain protein YP_001230903.1 PFAM: histone family protein DNA-binding protein YP_001230905.1 TIGRFAM: RNA methyltransferase, TrmA family; PFAM: deoxyribonuclease/rho motif-related TRAM; (Uracil-5)-methyltransferase YP_001230907.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001230908.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001230909.1 PFAM: tRNA synthetase, class II (D, K and N) YP_001230910.1 TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein YP_001230911.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits YP_001230912.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001230913.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase YP_001230914.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001230915.1 TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein YP_001230916.1 PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001230917.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001230918.1 PFAM: transposase, mutator type YP_001230919.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein YP_001230921.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; Sporulation domain protein YP_001230922.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II YP_001230923.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I YP_001230924.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074 YP_001230925.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001230926.1 PFAM: MCP methyltransferase, CheR-type YP_001230927.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein YP_001230928.1 PFAM: CheW domain protein YP_001230929.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein YP_001230931.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001230932.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein YP_001230933.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001230934.1 PFAM: heat shock protein DnaJ domain protein YP_001230935.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001230936.1 PFAM: Polyprenyl synthetase YP_001230937.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001230938.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001230939.1 TIGRFAM: transcription antitermination factor NusB; PFAM: NusB/RsmB/TIM44 YP_001230940.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001230941.1 PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II YP_001230942.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001230943.1 TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein YP_001230944.1 PFAM: ATP-cone domain protein YP_001230945.1 PFAM: CMP/dCMP deaminase, zinc-binding YP_001230948.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001230949.1 PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase YP_001230950.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin YP_001230951.1 PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein YP_001230952.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001230953.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_001230954.1 TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type YP_001230955.1 PFAM: Peptidoglycan-binding LysM YP_001230956.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001230957.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001230958.1 PFAM: protein of unknown function DUF224, cysteine-rich region domain protein YP_001230959.1 PFAM: FAD linked oxidase domain protein YP_001230960.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease YP_001230962.1 PFAM: Integrase, catalytic region YP_001230963.1 TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: peptidase S49 YP_001230965.1 PFAM: Desulfoferrodoxin, ferrous iron-binding region YP_001230966.1 PFAM: protein of unknown function DUF6, transmembrane YP_001230970.1 PFAM: UBA/THIF-type NAD/FAD binding protein YP_001230973.1 PFAM: protein of unknown function DUF955 YP_001230982.1 PFAM: glutamyl-tRNA synthetase, class Ic YP_001230983.1 PFAM: protein of unknown function DUF1255 YP_001230984.1 TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp YP_001230985.1 PFAM: nitrogen regulatory protein P-II YP_001230986.1 catalyzes the formation of 2-dehydropantoate from (R)-pantoate YP_001230987.1 PFAM: peptidase M23B YP_001230988.1 TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent, C-terminal domain protein; SMART: DEAD-like helicases-like YP_001230989.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001230990.1 PFAM: phosphoesterase, PA-phosphatase related YP_001230991.1 PFAM: lipopolysaccharide biosynthesis protein YP_001230992.1 PFAM: polysaccharide export protein; Fibronectin, type III domain protein YP_001230993.1 PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase YP_001230994.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding YP_001230995.1 catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA YP_001230996.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001230997.1 PFAM: ROSMUCR transcriptional regulator YP_001230998.1 TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_001230999.1 TIGRFAM: dethiobiotin synthase YP_001231000.1 TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III YP_001231002.1 PFAM: CBS domain containing protein; phosphoesterase, RecJ domain protein; Polynucleotide adenylyltransferase region; phosphoesterase, DHHA1 YP_001231003.1 PFAM: protein of unknown function DUF52 YP_001231004.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB YP_001231005.1 PFAM: chromosome segregation and condensation protein ScpA YP_001231006.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001231007.1 PFAM: peptidase M50 YP_001231008.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold YP_001231010.1 PFAM: PKD domain containing protein YP_001231011.1 hydrolyzes non-standard nucleotides such as xanthine and inosine YP_001231012.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001231014.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein YP_001231015.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001231017.1 PFAM: helix-turn-helix domain protein YP_001231018.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001231020.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001231023.1 PFAM: Allergen V5/Tpx-1 family protein YP_001231025.1 PFAM: protein of unknown function DUF497 YP_001231029.1 PFAM: amidohydrolase 2 YP_001231030.1 PFAM: Rubrerythrin YP_001231031.1 PFAM: Excinuclease ABC, C subunit domain protein YP_001231032.1 PFAM: General secretory system II, protein E domain protein YP_001231033.1 PFAM: membrane protein of unknown function YP_001231034.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001231035.1 PFAM: Radical SAM domain protein YP_001231036.1 PFAM: protein of unknown function DUF255 YP_001231037.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001231038.1 TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: peptidase S49 YP_001231039.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase YP_001231041.1 PFAM: response regulator receiver YP_001231042.1 PFAM: protein of unknown function DUF534 YP_001231044.1 TIGRFAM: cytochrome C family protein YP_001231045.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001231047.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001231049.1 PFAM: histone deacetylase superfamily YP_001231050.1 PFAM: Rh family protein/ammonium transporter YP_001231051.1 PFAM: response regulator receiver; General secretory system II, protein E domain protein YP_001231052.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001231053.1 PFAM: protein of unknown function DUF329 YP_001231054.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001231055.1 PFAM: Sporulation domain protein YP_001231056.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001231058.1 PFAM: Septum formation initiator YP_001231059.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001231060.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase YP_001231061.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001231062.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001231063.1 PFAM: PhoH family protein; SMART: Nucleotide binding protein, PINc YP_001231065.1 TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase, class V YP_001231066.1 PFAM: phosphoesterase, RecJ domain protein YP_001231069.1 TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain YP_001231070.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_001231071.1 PFAM: protein of unknown function UPF0079 YP_001231072.1 PFAM: CBS domain containing protein YP_001231073.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family N-terminal domain protein YP_001231074.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001231075.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp YP_001231076.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001231077.1 TIGRFAM: histidine kinase; PFAM: ATP-binding region, ATPase domain protein YP_001231078.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001231079.1 PFAM: Fibronectin, type III domain protein YP_001231080.1 PFAM: Fibronectin, type III domain protein YP_001231081.1 PFAM: glycosyl transferase, group 1 YP_001231082.1 PFAM: glycosyl transferase, family 2 YP_001231085.1 PFAM: glycosyl transferase, family 2 YP_001231086.1 PFAM: glycosyl transferase, group 1 YP_001231087.1 PFAM: protein of unknown function DUF201 YP_001231088.1 PFAM: polysaccharide deacetylase YP_001231089.1 PFAM: low molecular weight phosphotyrosine protein phosphatase YP_001231090.1 PFAM: O-antigen polymerase YP_001231091.1 PFAM: glycosyl transferase, group 1 YP_001231092.1 PFAM: glycosyl transferase, family 2 YP_001231094.1 TIGRFAM: eight transmembrane protein EpsH YP_001231095.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase YP_001231097.1 PFAM: glycosyl transferase, family 2 YP_001231099.1 PFAM: glycosyl transferase, family 2 YP_001231100.1 PFAM: glycosyl transferase, family 2 YP_001231102.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001231103.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase YP_001231104.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001231105.1 PFAM: Arginase/agmatinase/formiminoglutamase YP_001231107.1 PFAM: GCN5-related N-acetyltransferase YP_001231110.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001231111.1 PFAM: ABC-2 type transporter YP_001231112.1 PFAM: polysaccharide deacetylase YP_001231114.1 SMART: AAA ATPase YP_001231116.1 PFAM: lipopolysaccharide biosynthesis protein YP_001231117.1 PFAM: polysaccharide export protein YP_001231118.1 PFAM: sugar transferase YP_001231119.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001231120.1 PFAM: Abortive infection protein YP_001231123.1 PFAM: acriflavin resistance protein YP_001231124.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001231125.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001231126.1 TIGRFAM: metal dependent phophohydrolase; PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001231127.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001231128.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001231130.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001231131.1 PFAM: Rieske [2Fe-2S] domain protein YP_001231132.1 PFAM: Cytochrome b/b6, N-terminal domain; Cytochrome b/b6, C-terminal domain YP_001231134.1 catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate; this enzyme does not require the cofactor 2,3-bisphosphoglycerate as a phosphate donor; BPG-independent PGAM; aPGAM YP_001231135.1 TIGRFAM: tyrosine recombinase XerD; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001231136.1 TIGRFAM: protein-P-II uridylyltransferase; PFAM: amino acid-binding ACT domain protein; DNA polymerase, beta domain protein region; metal-dependent phosphohydrolase, HD sub domain; GlnD PII-uridylyltransferase; SMART: metal-dependent phosphohydrolase, HD region YP_001231137.1 PFAM: cell wall hydrolase/autolysin YP_001231138.1 This protein performs the mismatch recognition step during the DNA repair process YP_001231139.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001231140.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001231141.1 PFAM: iron-containing alcohol dehydrogenase YP_001231143.1 PFAM: Fibronectin, type III domain protein YP_001231146.1 PFAM: putative transposase YP_001231148.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001231149.1 TIGRFAM: prevent-host-death family protein YP_001231150.1 PFAM: PilT protein domain protein YP_001231151.1 TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase YP_001231156.1 PFAM: transposase, IS4 family protein YP_001231157.1 PFAM: CsbD family protein YP_001231159.1 PFAM: transport-associated protein; SMART: transport-associated protein and nodulation region, bacteria YP_001231160.1 PFAM: OmpW family protein YP_001231161.1 PFAM: molybdopterin binding domain YP_001231163.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001231164.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein YP_001231165.1 PFAM: Radical SAM domain protein YP_001231166.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein YP_001231167.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit; 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001231168.1 PFAM: electron transfer flavoprotein beta-subunit YP_001231170.1 PFAM: MOSC domain containing protein YP_001231171.1 TIGRFAM: molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001231172.1 PFAM: iron-containing alcohol dehydrogenase YP_001231173.1 PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase-like YP_001231174.1 PFAM: thiamineS protein YP_001231175.1 PFAM: UBA/THIF-type NAD/FAD binding protein YP_001231177.1 PFAM: Radical SAM domain protein YP_001231178.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001231179.1 PFAM: protein of unknown function DUF534 YP_001231180.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001231182.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001231183.1 TIGRFAM: putative regulatory protein, FmdB family YP_001231184.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001231187.1 PFAM: nitroreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001231189.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001231190.1 PFAM: protein of unknown function DUF214 YP_001231194.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase internal region YP_001231195.1 PFAM: response regulator receiver; LytTr DNA-binding region YP_001231196.1 PFAM: putative RNA methylase; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001231197.1 PFAM: regulatory protein, ArsR YP_001231200.1 PFAM: major facilitator superfamily MFS_1 YP_001231201.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family YP_001231202.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001231203.1 PFAM: SufBD protein YP_001231204.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001231206.1 PFAM: MCP methyltransferase, CheR-type YP_001231207.1 PFAM: PilT protein domain protein YP_001231208.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172 YP_001231211.1 PFAM: beta-lactamase domain protein YP_001231213.1 PFAM: transposase, IS4 family protein YP_001231214.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001231218.1 PFAM: 4-oxalocrotonate tautomerase YP_001231221.1 PFAM: HEPN domain protein YP_001231222.1 PFAM: DNA polymerase, beta domain protein region YP_001231223.1 PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001231231.1 PFAM: SMC domain protein YP_001231232.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001231233.1 PFAM: NUDIX hydrolase YP_001231234.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001231235.1 PFAM: extracellular solute-binding protein, family 1 YP_001231236.1 TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001231237.1 PFAM: Lytic transglycosylase, catalytic YP_001231238.1 TIGRFAM: L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase YP_001231239.1 PFAM: Chorismate mutase YP_001231241.1 PFAM: glutamate synthase, alpha subunit domain protein YP_001231242.1 PFAM: glutamine amidotransferase, class-II YP_001231243.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001231244.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001231245.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; ferredoxin-dependent glutamate synthase YP_001231246.1 PFAM: protein of unknown function UPF0044 YP_001231249.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001231250.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95 YP_001231251.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001231252.1 PFAM: aminotransferase, class I and II YP_001231254.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001231255.1 TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_001231256.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001231257.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001231258.1 TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: phosphoesterase PHP domain protein YP_001231259.1 stationary phase protein that binds TrpR repressor YP_001231261.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; Radical SAM domain protein YP_001231264.1 TIGRFAM: desulfoferrodoxin; PFAM: Desulfoferrodoxin, ferrous iron-binding region; Desulfoferrodoxin Dfx domain protein YP_001231265.1 PFAM: cytochrome c assembly protein YP_001231267.1 PFAM: major facilitator superfamily MFS_1 YP_001231269.1 PFAM: Carboxymuconolactone decarboxylase YP_001231270.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF362 YP_001231271.1 TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein YP_001231272.1 PFAM: NADPH-dependent FMN reductase YP_001231273.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001231274.1 PFAM: AMP-dependent synthetase and ligase YP_001231275.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001231277.1 PFAM: beta-ketoacyl synthase YP_001231278.1 PFAM: beta-ketoacyl synthase YP_001231280.1 catalyzes the formation of L-tryptophan from indole and L-serine YP_001231281.1 PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase, GAPDH domain protein YP_001231282.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001231283.1 catalyzes the formation of L-tryptophan from indole and L-serine YP_001231284.1 PFAM: protein of unknown function DUF169 YP_001231285.1 PFAM: regulatory protein, MarR YP_001231287.1 PFAM: major facilitator superfamily MFS_1 YP_001231288.1 PFAM: transglutaminase domain protein YP_001231289.1 PFAM: Rhodanese domain protein YP_001231290.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001231291.1 PFAM: Class I peptide chain release factor YP_001231292.1 TIGRFAM: metal dependent phophohydrolase YP_001231293.1 TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; protein phosphatase 2C domain protein YP_001231295.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; E1-E2 ATPase-associated domain protein YP_001231298.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001231300.1 PFAM: Radical SAM domain protein YP_001231301.1 TIGRFAM: putative outer membrane adhesin like protein; PFAM: Hemolysin-type calcium-binding region; Ig family protein; Haemolysin-type calcium binding domain protein; SMART: Dystroglycan-type cadherin domain protein YP_001231303.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein YP_001231304.1 PFAM: alpha/beta hydrolase fold YP_001231306.1 PFAM: transposase, mutator type YP_001231307.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001231309.1 TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001231310.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component YP_001231311.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component YP_001231312.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001231313.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein YP_001231314.1 PFAM: transposase, IS4 family protein YP_001231315.1 PFAM: Phosphoglycerate mutase YP_001231317.1 PFAM: thymidylate kinase YP_001231318.1 PFAM: thymidylate kinase YP_001231320.1 PFAM: CHAD domain containing protein YP_001231321.1 PFAM: Ppx/GppA phosphatase; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001231324.1 PFAM: GH3 auxin-responsive promoter YP_001231331.1 PFAM: lipopolysaccharide biosynthesis protein YP_001231333.1 PFAM: polysaccharide export protein YP_001231334.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001231335.1 PFAM: glycosyl transferase, family 4 YP_001231336.1 TIGRFAM: eight transmembrane protein EpsH YP_001231337.1 PFAM: Radical SAM domain protein YP_001231338.1 PFAM: glycosyl transferase, group 1 YP_001231339.1 PFAM: glycosyl transferase, group 1 YP_001231340.1 PFAM: glycoside hydrolase, family 20 YP_001231341.1 PFAM: glycosyl transferase, group 1 YP_001231342.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001231343.1 PFAM: glycosyl transferase, family 2 YP_001231345.1 PFAM: multi antimicrobial extrusion protein MatE; polysaccharide biosynthesis protein YP_001231348.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001231349.1 TIGRFAM: conserved repeat domain; PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protein of unknown function DUF11; peptidase domain protein YP_001231352.1 PFAM: glycosyl transferase, group 1; PHP C-terminal domain protein YP_001231355.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001231358.1 PFAM: Biopolymer transport protein ExbD/TolR YP_001231359.1 PFAM: MotA/TolQ/ExbB proton channel YP_001231360.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein YP_001231361.1 PFAM: Polypeptide-transport-associated protein domain protein, ShlB-type YP_001231362.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001231363.1 PFAM: peptidylprolyl isomerase, FKBP-type; Thioredoxin domain YP_001231366.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001231367.1 PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 region 1.2 YP_001231368.1 TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_001231369.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001231370.1 PFAM: regulatory protein, LuxR YP_001231371.1 PFAM: regulatory protein, MerR YP_001231372.1 PFAM: histone family protein DNA-binding protein YP_001231373.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001231374.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001231375.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001231376.1 PFAM: ribosomal protein L35 YP_001231377.1 TIGRFAM: translation initiation factor IF-3; PFAM: initiation factor 3 YP_001231378.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001231383.1 PFAM: protein of unknown function UPF0118 YP_001231384.1 PFAM: protein of unknown function DUF330 YP_001231385.1 PFAM: Mammalian cell entry related domain protein YP_001231386.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001231387.1 PFAM: protein of unknown function DUF140 YP_001231389.1 PFAM: CHAD domain containing protein YP_001231391.1 PFAM: thymidylate kinase YP_001231392.1 PFAM: thymidylate kinase YP_001231394.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase YP_001231396.1 PFAM: protein of unknown function DUF344 YP_001231397.1 SMART: Aldehyde ferredoxin oxidoreductase-like YP_001231398.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001231399.1 PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001231400.1 PFAM: respiratory-chain NADH dehydrogenase, subunit 1 YP_001231401.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001231402.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001231403.1 PFAM: pyruvate kinase YP_001231404.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001231405.1 catalyzes the formation of fructose 1,6-bisphosphate from fructose 6-phosphate and diphosphate YP_001231407.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001231409.1 TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase, family 35 YP_001231410.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001231411.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein YP_001231412.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001231417.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001231418.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001231422.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001231423.1 PFAM: transposase, IS4 family protein YP_001231425.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001231426.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001231427.1 PFAM: type II secretion system protein YP_001231428.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001231429.1 TIGRFAM: type IV-A pilus assembly ATPase PilB; PFAM: type II secretion system protein E; General secretory system II, protein E domain protein YP_001231430.1 TIGRFAM: shikimate 5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding, N-terminal domain protein YP_001231432.1 PFAM: conserved hypothetical protein 374 YP_001231433.1 TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; cytidylyltransferase YP_001231434.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase YP_001231435.1 PFAM: CheB methylesterase; response regulator receiver YP_001231436.1 PFAM: MCP methyltransferase, CheR-type YP_001231437.1 PFAM: HEAT domain containing protein; PBS lyase HEAT domain protein repeat-containing protein YP_001231438.1 PFAM: MCP methyltransferase, CheR-type YP_001231439.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001231440.1 PFAM: CheW domain protein YP_001231441.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein YP_001231442.1 PFAM: response regulator receiver YP_001231443.1 PFAM: response regulator receiver YP_001231444.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001231445.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; SMART: PAS domain containing protein YP_001231446.1 TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B, OB region N-terminal domain; SMART: Cold shock protein YP_001231447.1 PFAM: TPR repeat-containing protein; Lytic transglycosylase, catalytic; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001231448.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001231450.1 PFAM: regulatory protein, MarR YP_001231451.1 PFAM: outer membrane efflux protein YP_001231452.1 PFAM: secretion protein HlyD family protein YP_001231453.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001231454.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001231455.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001231460.1 PFAM: cytochrome B561 YP_001231462.1 PFAM: CopG domain protein DNA-binding domain protein YP_001231463.1 PFAM: PemK family protein YP_001231464.1 PFAM: CopG domain protein DNA-binding domain protein YP_001231465.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system YP_001231468.1 TIGRFAM: CRISPR-associated protein Cas2; PFAM: protein of unknown function DUF196 YP_001231469.1 PFAM: protein of unknown function DUF559 YP_001231470.1 TIGRFAM: CRISPR-associated protein Cas4 YP_001231473.1 TIGRFAM: putative addiction module component, TIGR02574 family YP_001231475.1 PFAM: ATP-binding region, ATPase domain protein YP_001231476.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001231477.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001231479.1 PFAM: protein of unknown function DUF147 YP_001231480.1 TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS YP_001231481.1 TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001231482.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; tRNA(Ile)-lysidine synthetase domain protein YP_001231484.1 PFAM: filamentation induced by cAMP protein Fic YP_001231485.1 PFAM: AAA-4 family protein YP_001231487.1 PFAM: DNA methylase N-4/N-6 domain protein YP_001231489.1 SMART: TIR protein YP_001231490.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001231491.1 PFAM: response regulator receiver YP_001231498.1 PFAM: magnesium chelatase, ChlI subunit; response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001231499.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001231500.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein YP_001231502.1 PFAM: NHL repeat containing protein; SMP-30/Gluconolaconase/LRE domain protein YP_001231504.1 TIGRFAM: cytochrome C family protein YP_001231505.1 PFAM: NHL repeat containing protein YP_001231506.1 TIGRFAM: cytochrome C family protein YP_001231507.1 TIGRFAM: cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001231508.1 TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein YP_001231509.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein YP_001231513.1 PFAM: major facilitator superfamily MFS_1 YP_001231514.1 SMART: Parallel beta-helix repeat YP_001231515.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001231516.1 PFAM: cytochrome c biogenesis protein, transmembrane region; high-affinity nickel-transporter YP_001231519.1 SMART: Parallel beta-helix repeat YP_001231522.1 PFAM: Polysulphide reductase, NrfD YP_001231523.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001231524.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001231526.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001231527.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001231528.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001231529.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2 YP_001231530.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase, dimerisation and phosphoacceptor region; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001231531.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001231533.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component YP_001231534.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001231535.1 PFAM: Citrate transporter YP_001231536.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001231537.1 PFAM: carbon starvation protein CstA YP_001231538.1 PFAM: response regulator receiver; LytTr DNA-binding region YP_001231539.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type, transmembrane region YP_001231541.1 PFAM: SMC domain protein YP_001231542.1 TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding YP_001231543.1 TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase YP_001231544.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001231545.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001231546.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001231547.1 TIGRFAM: RNA methyltransferase, TrmA family; PFAM: deoxyribonuclease/rho motif-related TRAM; (Uracil-5)-methyltransferase YP_001231549.1 TIGRFAM: metal dependent phophohydrolase; PFAM: histidine kinase, HAMP region domain protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001231550.1 PFAM: transposase, IS4 family protein YP_001231551.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_001231552.1 PFAM: HhH-GPD family protein YP_001231554.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein YP_001231555.1 PFAM: transport-associated protein YP_001231557.1 PFAM: MgtC/SapB transporter YP_001231560.1 PFAM: Sporulation domain protein YP_001231561.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001231562.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_001231563.1 TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; Helix-turn-helix, type 11 domain protein YP_001231564.1 TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_001231565.1 PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein YP_001231570.1 PFAM: Heat shock protein 70 YP_001231571.1 PFAM: gas vesicle protein GVPa YP_001231572.1 PFAM: Gas vesicle synthesis GvpLGvpF YP_001231574.1 PFAM: gas vesicle protein GVPa YP_001231575.1 TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase YP_001231577.1 PFAM: Gas vesicle G YP_001231578.1 PFAM: heat shock protein DnaJ domain protein; Gas vesicle synthesis GvpLGvpF YP_001231579.1 PFAM: heat shock protein Hsp20 YP_001231580.1 PFAM: Gas vesicle synthesis GvpLGvpF YP_001231582.1 TIGRFAM: gas vesicle protein GvpN; PFAM: ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001231585.1 involved in formation of gas vesicle which are protein structures that contain gas involved in buoyancy; part of an operon of other gas vesicle synthesis proteins YP_001231586.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001231587.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001231588.1 TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein; AAA ATPase, central domain protein; cell division protein 48, CDC48, domain 2; SMART: AAA ATPase YP_001231591.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001231592.1 PFAM: flavin reductase domain protein, FMN-binding YP_001231595.1 PFAM: Haloacid dehalogenase domain protein hydrolase YP_001231596.1 PFAM: HNH endonuclease; SMART: HNH nuclease YP_001231597.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001231598.1 PFAM: phospholipid/glycerol acyltransferase YP_001231599.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001231600.1 PFAM: Radical SAM domain protein YP_001231603.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein YP_001231604.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain YP_001231606.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001231608.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase YP_001231609.1 TIGRFAM: D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA YP_001231610.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_001231611.1 PFAM: glycosyl transferase, family 2 YP_001231612.1 TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell division protein FtsA; cell shape determining protein MreB/Mrl YP_001231614.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001231615.1 TIGRFAM: integron integrase; PFAM: phage integrase family protein YP_001231617.1 PFAM: putative transposase YP_001231618.1 PFAM: phage integrase family protein YP_001231620.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase YP_001231621.1 PFAM: Integrase, catalytic region YP_001231622.1 PFAM: putative transposase YP_001231624.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001231628.1 PFAM: Myosin, N-terminal, SH3 domain protein YP_001231629.1 PFAM: transposase, mutator type YP_001231630.1 PFAM: protein of unknown function DUF1568 YP_001231631.1 PFAM: transposase, IS4 family protein YP_001231632.1 PFAM: protein of unknown function DUF1568 YP_001231634.1 PFAM: Alkaline phosphatase YP_001231635.1 PFAM: protein of unknown function DUF1566 YP_001231636.1 PFAM: peptidase C45, acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase YP_001231639.1 PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001231640.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region YP_001231642.1 PFAM: CoA-binding domain protein YP_001231643.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001231644.1 PFAM: Transketolase, central region; Transketolase domain protein YP_001231645.1 PFAM: dehydrogenase, E1 component YP_001231647.1 PFAM: Activator of Hsp90 ATPase 1 family protein YP_001231648.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001231649.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001231650.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; GAF domain protein; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein YP_001231651.1 PFAM: LemA family protein YP_001231652.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_001231653.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001231655.1 PFAM: Ferritin, Dps family protein YP_001231657.1 PFAM: band 7 protein YP_001231658.1 PFAM: protein of unknown function DUF107 YP_001231659.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001231667.1 PFAM: AAA-4 family protein YP_001231668.1 PFAM: thioesterase superfamily protein YP_001231669.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001231670.1 TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily YP_001231672.1 TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein YP_001231673.1 PFAM: beta-lactamase domain protein YP_001231674.1 TIGRFAM: metal dependent phophohydrolase; PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001231676.1 PFAM: response regulator receiver YP_001231677.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001231678.1 PFAM: UspA domain protein YP_001231679.1 PFAM: response regulator receiver YP_001231680.1 PFAM: GAF domain protein YP_001231681.1 SMART: helix-turn-helix domain protein YP_001231682.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001231683.1 PFAM: PfkB domain protein YP_001231684.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001231687.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: pseudouridine synthase YP_001231694.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001231696.1 PFAM: Roadblock/LC7 family protein YP_001231698.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001231701.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_001231702.1 PFAM: protein of unknown function DUF985 YP_001231703.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001231704.1 PFAM: PDZ/DHR/GLGF domain protein YP_001231705.1 TIGRFAM: glutaredoxin-like protein, YruB-family; PFAM: glutaredoxin YP_001231707.1 PFAM: YdjC family protein YP_001231708.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001231709.1 PFAM: purine or other phosphorylase, family 1 YP_001231710.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein YP_001231711.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein YP_001231712.1 PFAM: PTS system fructose subfamily IIA component YP_001231713.1 PFAM: uncharacterised P-loop ATPase protein UPF0042 YP_001231714.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system YP_001231715.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_001231716.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA YP_001231717.1 TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 factor; sigma-54 factor, core-binding region; sigma-54, DNA-binding domain protein YP_001231718.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001231719.1 PFAM: OstA family protein YP_001231720.1 PFAM: protein of unknown function DUF1239 YP_001231721.1 TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family YP_001231722.1 TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001231723.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001231724.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001231725.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001231726.1 PFAM: EAL domain protein; HDOD YP_001231727.1 PFAM: CheB methylesterase; response regulator receiver YP_001231728.1 PFAM: CheD family protein YP_001231729.1 PFAM: MCP methyltransferase, CheR-type YP_001231730.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001231731.1 PFAM: CheW domain protein YP_001231732.1 PFAM: response regulator receiver YP_001231733.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001231734.1 TIGRFAM: PAS sensor protein; PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein YP_001231736.1 PFAM: CheW domain protein YP_001231737.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001231738.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein YP_001231739.1 PFAM: response regulator receiver YP_001231740.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS YP_001231744.1 PFAM: iron dependent repressor; FeoA family protein YP_001231746.1 TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein YP_001231747.1 PFAM: ferric-uptake regulator YP_001231748.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: NHL repeat containing protein; Ig domain protein, group 2 domain protein YP_001231750.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001231751.1 PFAM: regulatory protein, ArsR; UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001231752.1 PFAM: 2-nitropropane dioxygenase, NPD YP_001231753.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein YP_001231755.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001231756.1 SMART: LamG domain protein jellyroll fold domain protein YP_001231757.1 TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein YP_001231758.1 PFAM: PilT protein domain protein YP_001231761.1 PFAM: protein of unknown function DUF1568; SMART: Chromosomal replication initiator, DnaA C-terminal domain YP_001231765.1 PFAM: protein of unknown function DUF1568 YP_001231768.1 PFAM: peptidase S41 YP_001231769.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001231772.1 PFAM: Integrase, catalytic region YP_001231773.1 PFAM: Integrase, catalytic region YP_001231779.1 PFAM: coenzyme A transferase YP_001231780.1 PFAM: coenzyme A transferase YP_001231781.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001231782.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit YP_001231783.1 PFAM: electron transfer flavoprotein beta-subunit YP_001231784.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein YP_001231785.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001231786.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001231787.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001231788.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001231789.1 PFAM: Helix-turn-helix, type 11 domain protein YP_001231790.1 PFAM: chemotaxis sensory transducer; Cache, type 2 domain protein YP_001231791.1 PFAM: glycosyl transferase, family 4; FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type YP_001231793.1 PFAM: multicopper oxidase, type 2; FG-GAP repeat protein YP_001231795.1 PFAM: glycosyl transferase, group 1 YP_001231796.1 PFAM: glycoside hydrolase, family 20 YP_001231797.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001231801.1 PFAM: glycosyl transferase, family 2 YP_001231802.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001231803.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001231804.1 PFAM: virulence factor MVIN family protein YP_001231805.1 PFAM: lipopolysaccharide biosynthesis protein YP_001231806.1 PFAM: polysaccharide export protein YP_001231807.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001231810.1 PFAM: Cache, type 2 domain protein YP_001231811.1 PFAM: filamentation induced by cAMP protein Fic YP_001231812.1 PFAM: Ricin B lectin YP_001231813.1 PFAM: filamentation induced by cAMP protein Fic YP_001231816.1 PFAM: Biopolymer transport protein ExbD/TolR YP_001231817.1 PFAM: MotA/TolQ/ExbB proton channel YP_001231819.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein YP_001231820.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein YP_001231823.1 PFAM: OmpA/MotB domain protein YP_001231824.1 TIGRFAM: conserved repeat domain; PFAM: protein of unknown function DUF11 YP_001231826.1 PFAM: phage integrase family protein YP_001231828.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001231829.1 PFAM: secretion protein HlyD family protein YP_001231830.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001231831.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein YP_001231832.1 PFAM: beta-ketoacyl synthase; phosphopantetheine-binding YP_001231833.1 PFAM: beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR YP_001231834.1 PFAM: beta-ketoacyl synthase; phosphopantetheine-binding YP_001231835.1 PFAM: beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR YP_001231836.1 PFAM: beta-ketoacyl synthase; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR YP_001231837.1 PFAM: transposase, mutator type YP_001231838.1 PFAM: Rubredoxin-type Fe(Cys)4 protein YP_001231839.1 TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_001231840.1 TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; PFAM: transferase hexapeptide repeat containing protein; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD YP_001231841.1 PFAM: transposase IS3/IS911 family protein YP_001231842.1 PFAM: helix-turn-helix- domain containing protein, AraC type; response regulator receiver YP_001231843.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; Malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein; 2-nitropropane dioxygenase, NPD YP_001231844.1 PFAM: acyl transferase domain protein YP_001231845.1 PFAM: 4'-phosphopantetheinyl transferase YP_001231846.1 PFAM: beta-lactamase domain protein YP_001231847.1 PFAM: phage integrase family protein YP_001231848.1 PFAM: putative transposase YP_001231850.1 PFAM: regulatory protein, LuxR; Autoinducer-binding domain protein YP_001231854.1 PFAM: Polynucleotide adenylyltransferase region YP_001231856.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001231857.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001231858.1 TIGRFAM: inosine-5'-monophosphate dehydrogenase; PFAM: CBS domain containing protein; IMP dehydrogenase/GMP reductase YP_001231859.1 PFAM: peptidase M20; peptidase M42 family protein YP_001231860.1 PFAM: protein of unknown function DUF151 YP_001231861.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001231865.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001231866.1 TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta YP_001231868.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001231870.1 PFAM: response regulator receiver YP_001231871.1 PFAM: GAF domain protein YP_001231872.1 PFAM: CheB methylesterase; response regulator receiver YP_001231873.1 PFAM: MCP methyltransferase, CheR-type YP_001231874.1 PFAM: HEAT domain containing protein; PBS lyase HEAT domain protein repeat-containing protein YP_001231875.1 TIGRFAM: MJ0042 family finger-like protein; PFAM: response regulator receiver YP_001231876.1 PFAM: CheW domain protein YP_001231877.1 PFAM: response regulator receiver YP_001231878.1 PFAM: CheW domain protein YP_001231879.1 SMART: AAA ATPase YP_001231880.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein YP_001231881.1 PFAM: response regulator receiver YP_001231882.1 PFAM: response regulator receiver YP_001231883.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001231884.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001231885.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001231886.1 PFAM: ribonuclease III; double-stranded RNA binding domain protein YP_001231887.1 PFAM: thymidylate kinase YP_001231888.1 TIGRFAM: DNA polymerase III, delta prime subunit YP_001231889.1 PFAM: PSP1 domain protein YP_001231890.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001231891.1 PFAM: protein of unknown function DUF218 YP_001231892.1 required for 70S ribosome assembly YP_001231893.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP YP_001231894.1 TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_001231895.1 TIGRFAM: DNA-directed RNA polymerase, omega subunit; PFAM: RNA polymerase Rpb6 YP_001231896.1 Essential for recycling GMP and indirectly, cGMP YP_001231897.1 PFAM: YicC N-terminal domain protein; domain of unknown function DUF1732 YP_001231898.1 PFAM: PilT protein domain protein YP_001231899.1 PFAM: CopG domain protein DNA-binding domain protein YP_001231902.1 PFAM: glycosyl transferase, family 2 YP_001231903.1 PFAM: glycosyl transferase, group 1 YP_001231904.1 PFAM: glycosyl transferase, family 2 YP_001231905.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001231907.1 PFAM: DNA polymerase, beta domain protein region YP_001231908.1 TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein YP_001231911.1 PFAM: sugar transferase YP_001231915.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001231916.1 PFAM: glycosyl transferase, group 1 YP_001231917.1 PFAM: glycosyl transferase, group 1 YP_001231919.1 PFAM: glycosyl transferase, family 2 YP_001231920.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain YP_001231921.1 PFAM: transferase hexapeptide repeat containing protein YP_001231922.1 PFAM: glycosyl transferase, family 2 YP_001231923.1 PFAM: polysaccharide biosynthesis protein YP_001231924.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001231925.1 PFAM: WxcM domain protein, C-terminal domain protein YP_001231926.1 PFAM: Methyltransferase type 12 YP_001231930.1 TIGRFAM: HAD-superfamily phosphatase, subfamily IIIC; FkbH like protein YP_001231933.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system YP_001231936.1 PFAM: protein of unknown function DUF86 YP_001231937.1 PFAM: DNA polymerase, beta domain protein region YP_001231943.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase YP_001231944.1 TIGRFAM: GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase YP_001231945.1 TIGRFAM: cytidyltransferase-related domain; rfaE bifunctional protein; PFAM: cytidylyltransferase; PfkB domain protein YP_001231946.1 PFAM: S23 ribosomal protein YP_001231948.1 TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase, family 9 YP_001231949.1 PFAM: glycosyl transferase, family 9 YP_001231952.1 PFAM: glycosyl transferase, family 2 YP_001231953.1 PFAM: glycosyl transferase, family 2 YP_001231954.1 PFAM: glycosyl transferase, group 1 YP_001231955.1 PFAM: glycosyl transferase, family 2 YP_001231956.1 PFAM: glycosyl transferase, group 1 YP_001231958.1 PFAM: glycosyl transferase, family 2 YP_001231959.1 PFAM: glycosyl transferase, family 2 YP_001231960.1 PFAM: glycosyl transferase, family 9 YP_001231961.1 PFAM: protein of unknown function DUF343 YP_001231962.1 TIGRFAM: tetraacyldisaccharide 4'-kinase; PFAM: Tetraacyldisaccharide-1-P 4'-kinase YP_001231963.1 PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein YP_001231964.1 PFAM: lipid A biosynthesis acyltransferase YP_001231965.1 TIGRFAM: lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001231966.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001231967.1 TIGRFAM: acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase YP_001231968.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001231969.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001231970.1 PFAM: outer membrane chaperone Skp (OmpH) YP_001231971.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein YP_001231972.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001231973.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214 YP_001231974.1 TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S); tRNA synthetase, class II (D, K and N); nucleic acid binding, OB-fold, tRNA/helicase-type YP_001231975.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001231976.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001231977.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_001231978.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001231979.1 PFAM: alpha/beta hydrolase fold YP_001231980.1 TIGRFAM: 8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II YP_001231981.1 PFAM: metallophosphoesterase YP_001231983.1 TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001231984.1 amylomaltase; acts to release glucose from maltodextrins YP_001231986.1 TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001231989.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001231990.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001231991.1 TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family YP_001231992.1 TIGRFAM: tRNA-guanine transglycosylase, various specificities; queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase YP_001231993.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001231994.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase YP_001231995.1 TIGRFAM: integral membrane protein MviN; PFAM: multi antimicrobial extrusion protein MatE; virulence factor MVIN family protein YP_001231997.1 PFAM: class II aldolase/adducin family protein YP_001231998.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001232001.1 PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase-like YP_001232002.1 PFAM: mannose-6-phosphate isomerase, type II; Nucleotidyl transferase YP_001232003.1 PFAM: mannose-6-phosphate isomerase, type II; Cupin 2, conserved barrel domain protein YP_001232004.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase YP_001232005.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001232008.1 PFAM: OstA family protein; Organic solvent tolerance protein YP_001232009.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001232011.1 TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit YP_001232012.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001232013.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001232017.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001232018.1 SMART: Water Stress and Hypersensitive response YP_001232020.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001232021.1 PFAM: acriflavin resistance protein YP_001232022.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001232023.1 PFAM: tRNA/rRNA methyltransferase (SpoU) YP_001232025.1 PFAM: import inner membrane translocase, subunit Tim44 YP_001232027.1 PFAM: metal-dependent phosphohydrolase, HD sub domain YP_001232028.1 PFAM: type IV pilus assembly PilZ YP_001232030.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; E1-E2 ATPase-associated domain protein YP_001232031.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001232037.1 PFAM: NUDIX hydrolase YP_001232038.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein; Cache, type 2 domain protein YP_001232039.1 PFAM: regulatory protein, ArsR YP_001232040.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001232041.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001232042.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001232043.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001232044.1 PFAM: aldehyde dehydrogenase YP_001232045.1 PFAM: protein phosphatase 2C domain protein YP_001232046.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; Ig family protein YP_001232048.1 PFAM: Integrase, catalytic region YP_001232049.1 PFAM: FxsA cytoplasmic membrane protein YP_001232050.1 PFAM: carbonic anhydrase YP_001232051.1 TIGRFAM: molybdate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001232052.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001232053.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001232054.1 PFAM: TOBE domain protein YP_001232055.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001232056.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001232057.1 PFAM: cobalamin synthesis protein, P47K YP_001232059.1 PFAM: phosphate-selective porin O and P YP_001232061.1 TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; Methyltransferase type 11 YP_001232063.1 PFAM: regulatory protein, LuxR; GAF domain protein YP_001232065.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001232066.1 PFAM: Auxin Efflux Carrier YP_001232068.1 PFAM: DoxX family protein YP_001232070.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001232073.1 PFAM: Roadblock/LC7 family protein YP_001232074.1 PFAM: domain of unknown function DUF1745 YP_001232077.1 PFAM: protein of unknown function DUF547 YP_001232081.1 PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein YP_001232082.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; uncharacterized peroxidase-related enzyme; PFAM: Carboxymuconolactone decarboxylase YP_001232083.1 PFAM: regulatory protein, TetR YP_001232084.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001232085.1 PFAM: inositol monophosphatase YP_001232090.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein YP_001232091.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001232092.1 PFAM: outer membrane efflux protein YP_001232094.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001232095.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter YP_001232096.1 PFAM: nitrogen regulatory protein P-II YP_001232098.1 in Methanococcus jannaschii this protein catalyzes the condensation of alpha-ketoglutarate and acetyl-CoA to form trans-homoaconitate; functions in alphaketosuberate synthesis which is a precursor in coenzyme B and biotin synthesis YP_001232099.1 PFAM: Na+/H+ antiporter NhaA YP_001232100.1 TIGRFAM: formate dehydrogenase family accessory protein FdhD; PFAM: formate dehydrogenase, subunit FdhD YP_001232102.1 TIGRFAM: formate dehydrogenase, gamma subunit YP_001232103.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001232104.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; Contains selenocysteine YP_001232105.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001232106.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001232107.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001232108.1 PFAM: PemK family protein YP_001232109.1 PFAM: SpoVT/AbrB domain protein YP_001232111.1 PFAM: Radical SAM domain protein YP_001232112.1 PFAM: protein of unknown function DUF820 YP_001232113.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001232114.1 TIGRFAM: formate dehydrogenase family accessory protein FdhD; PFAM: formate dehydrogenase, subunit FdhD YP_001232115.1 PFAM: Polysulphide reductase, NrfD YP_001232116.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001232117.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; Contains selenocysteine YP_001232118.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001232119.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001232120.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001232121.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001232122.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV YP_001232123.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein YP_001232124.1 TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase YP_001232125.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001232126.1 TIGRFAM: MJ0042 family finger-like protein YP_001232127.1 TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001232128.1 PFAM: protein of unknown function DUF1573 YP_001232129.1 PFAM: beta-lactamase domain protein YP_001232131.1 PFAM: BRO domain protein YP_001232133.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001232134.1 PFAM: Methyltransferase type 11 YP_001232135.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001232136.1 PFAM: protein of unknown function DUF214 YP_001232137.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001232138.1 PFAM: outer membrane efflux protein YP_001232139.1 PFAM: regulatory protein, TetR YP_001232141.1 PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type YP_001232143.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001232144.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001232146.1 TIGRFAM: cytochrome C family protein YP_001232148.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2+ transporter protein, CorA family protein YP_001232149.1 PFAM: plasmid stabilization system YP_001232150.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172 YP_001232153.1 PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; conserved hypothetical protein 156 YP_001232154.1 PFAM: glycosyl hydrolase, BNR repeat-containing protein YP_001232155.1 TIGRFAM: cytochrome C family protein YP_001232156.1 TIGRFAM: cytochrome C family protein YP_001232157.1 TIGRFAM: cytochrome C family protein YP_001232160.1 PFAM: surface antigen msp4 family protein YP_001232164.1 PFAM: helix-turn-helix domain protein YP_001232165.1 PFAM: protein of unknown function DUF107 YP_001232166.1 PFAM: band 7 protein YP_001232169.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001232172.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001232174.1 PFAM: protein of unknown function DUF480 YP_001232175.1 PFAM: protein of unknown function DUF55 YP_001232176.1 PFAM: protein of unknown function DUF1456 YP_001232177.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001232178.1 PFAM: Pirin domain protein; Pirin domain protein YP_001232179.1 PFAM: alpha/beta hydrolase fold YP_001232180.1 PFAM: protein of unknown function DUF72 YP_001232181.1 PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase YP_001232182.1 PFAM: DNA primase, small subunit YP_001232183.1 PFAM: Ku domain protein YP_001232184.1 PFAM: Ku domain protein YP_001232187.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001232188.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; Methyltransferase type 11; Methyltransferase type 12; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001232189.1 PFAM: zinc/iron permease YP_001232191.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001232192.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001232193.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3-methyltransferase YP_001232195.1 PFAM: acriflavin resistance protein YP_001232197.1 PFAM: acriflavin resistance protein YP_001232200.1 PFAM: Propeptide, PepSY amd peptidase M4 YP_001232202.1 PFAM: Peptidoglycan-binding domain 1 protein YP_001232203.1 PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase YP_001232206.1 PFAM: sigma-54 factor, interaction domain-containing protein; SMART: AAA ATPase YP_001232209.1 TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase YP_001232210.1 PFAM: cobalamin B12-binding domain protein YP_001232211.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate enzyme domain protein TPP-binding YP_001232212.1 NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate YP_001232213.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase YP_001232214.1 TIGRFAM: succinyl-CoA synthetase, beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein YP_001232215.1 PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding YP_001232216.1 PFAM: carboxyl transferase YP_001232217.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001232221.1 PFAM: PilT protein domain protein YP_001232222.1 TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein YP_001232223.1 PFAM: metal-dependent phosphohydrolase, HD sub domain YP_001232225.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001232226.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein YP_001232227.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001232228.1 PFAM: regulatory protein, TetR YP_001232229.1 TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_001232230.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001232231.1 PFAM: helix-turn-helix- domain containing protein, AraC type; transcription activator, effector binding YP_001232233.1 PFAM: penicillin-binding protein, transpeptidase YP_001232234.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001232235.1 PFAM: pentapeptide repeat protein YP_001232237.1 PFAM: Methyltransferase type 11 YP_001232238.1 PFAM: restriction endonuclease YP_001232240.1 PFAM: protein of unknown function DUF81 YP_001232241.1 PFAM: helix-turn-helix, HxlR type YP_001232242.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001232243.1 PFAM: nitroreductase YP_001232244.1 PFAM: beta-lactamase domain protein YP_001232245.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001232246.1 TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_001232248.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001232249.1 PFAM: Helix-turn-helix, type 11 domain protein YP_001232251.1 PFAM: NADPH-dependent FMN reductase YP_001232252.1 PFAM: regulatory protein, MerR YP_001232253.1 PFAM: protein of unknown function DUF1697 YP_001232254.1 PFAM: aldo/keto reductase YP_001232255.1 PFAM: regulatory protein, MarR YP_001232256.1 PFAM: ThiJ/PfpI domain protein YP_001232257.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001232258.1 PFAM: ThiJ/PfpI domain protein YP_001232259.1 PFAM: Excinuclease ABC, C subunit domain protein; regulatory protein, ArsR YP_001232260.1 PFAM: iron-containing alcohol dehydrogenase YP_001232261.1 TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; protein phosphatase 2C domain protein YP_001232262.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA YP_001232265.1 PFAM: aldehyde dehydrogenase YP_001232266.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; SMART: AAA ATPase YP_001232267.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain YP_001232268.1 TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region YP_001232269.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV YP_001232270.1 PFAM: ABC transporter related; TOBE domain protein; transport-associated protein OB domain protein; SMART: AAA ATPase YP_001232271.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001232273.1 PFAM: molybdopterin biosynthesis MoaE protein YP_001232274.1 PFAM: regulatory protein, IclR YP_001232276.1 PFAM: thiamineS protein YP_001232278.1 PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase-like YP_001232279.1 PFAM: domain of unknown function DUF1745 YP_001232281.1 PFAM: glycosyl transferase, family 2 YP_001232282.1 PFAM: electron transfer flavoprotein beta-subunit YP_001232283.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001232284.1 PFAM: monooxygenase, FAD-binding; HI0933 family protein; FAD dependent oxidoreductase YP_001232285.1 PFAM: electron transfer flavoprotein, alpha subunit YP_001232286.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001232287.1 PFAM: Radical SAM domain protein YP_001232289.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001232290.1 TIGRFAM: hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain protein YP_001232291.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain YP_001232292.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001232293.1 PFAM: VWA containing CoxE family protein YP_001232294.1 PFAM: ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001232295.1 PFAM: iron-containing alcohol dehydrogenase YP_001232296.1 PFAM: Radical SAM domain protein YP_001232297.1 PFAM: MOSC domain containing protein YP_001232298.1 TIGRFAM: molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001232299.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001232300.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001232301.1 PFAM: iron-containing alcohol dehydrogenase YP_001232307.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001232309.1 PFAM: protein of unknown function DUF224, cysteine-rich region domain protein YP_001232310.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001232311.1 PFAM: methyl-viologen-reducing hydrogenase, delta subunit YP_001232312.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001232313.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001232314.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001232315.1 PFAM: Radical SAM domain protein YP_001232318.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001232320.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001232323.1 PFAM: outer membrane lipoprotein carrier protein LolA YP_001232324.1 PFAM: protein of unknown function DUF1016 YP_001232325.1 TIGRFAM: death-on-curing family protein; PFAM: Death-on-curing protein YP_001232327.1 PFAM: N-6 DNA methylase; protein of unknown function DUF450 YP_001232328.1 PFAM: restriction endonuclease YP_001232329.1 PFAM: helix-turn-helix domain protein YP_001232331.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_001232332.1 PFAM: beta-ketoacyl synthase YP_001232333.1 PFAM: beta-ketoacyl synthase YP_001232334.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001232335.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001232336.1 PFAM: thioesterase superfamily protein YP_001232338.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001232340.1 PFAM: lipid A biosynthesis acyltransferase YP_001232341.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001232342.1 PFAM: Radical SAM domain protein YP_001232343.1 PFAM: glycosyl transferase, family 2 YP_001232344.1 PFAM: polysaccharide deacetylase YP_001232345.1 PFAM: aminodeoxychorismate lyase YP_001232346.1 PFAM: TPR repeat-containing protein; heat shock protein DnaJ domain protein; response regulator receiver; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001232348.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II YP_001232349.1 TIGRFAM: putative undecaprenol kinase; PFAM: Bacitracin resistance protein BacA YP_001232350.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein YP_001232351.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001232352.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001232353.1 TIGRFAM: cytochrome C family protein YP_001232356.1 PFAM: peptidase M16 domain protein YP_001232357.1 PFAM: peptidase M16 domain protein YP_001232359.1 PFAM: protein of unknown function DUF1568; Chromosomal replication initiator, DnaA C-terminal domain YP_001232360.1 PFAM: alpha/beta hydrolase fold YP_001232363.1 TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein YP_001232365.1 PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001232366.1 PFAM: glucose-inhibited division protein A; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001232368.1 PFAM: protein of unknown function DUF342 YP_001232369.1 TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase YP_001232370.1 PFAM: regulatory protein, IclR YP_001232371.1 PFAM: UspA domain protein YP_001232372.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001232373.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001232375.1 PFAM: response regulator receiver YP_001232379.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001232382.1 PFAM: histidine kinase, HAMP region domain protein YP_001232384.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein YP_001232385.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001232386.1 TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase YP_001232387.1 TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001232388.1 PFAM: AAA-4 family protein YP_001232391.1 PFAM: transposase, mutator type YP_001232392.1 PFAM: fumarylacetoacetate (FAA) hydrolase YP_001232394.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001232396.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001232397.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001232398.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001232399.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001232400.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001232401.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001232403.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001232404.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001232405.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001232406.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001232407.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001232408.1 TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase YP_001232409.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001232410.1 PFAM: carbonic anhydrase YP_001232411.1 PFAM: alanine racemase domain protein YP_001232412.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001232414.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_001232415.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity YP_001232416.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein YP_001232417.1 PFAM: Peptidoglycan-binding LysM YP_001232418.1 TIGRFAM: Tetratricopeptide domain protein YP_001232419.1 PFAM: peptidase U32 YP_001232420.1 PFAM: glycosyl transferase, family 39 YP_001232421.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001232422.1 PFAM: glycosyl transferase, family 2 YP_001232423.1 PFAM: formyl transferase domain protein YP_001232424.1 PFAM: NAD-dependent epimerase/dehydratase YP_001232425.1 PFAM: polysaccharide deacetylase YP_001232427.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001232429.1 PFAM: transposase, mutator type YP_001232430.1 PFAM: transposase, mutator type YP_001232431.1 PFAM: Mammalian cell entry related domain protein YP_001232432.1 PFAM: protein of unknown function DUF140 YP_001232434.1 PFAM: aconitate hydratase domain protein YP_001232435.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis YP_001232436.1 PFAM: conserved hypothetical protein 730 YP_001232437.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001232441.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001232442.1 TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001232443.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_001232444.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001232445.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001232446.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein YP_001232447.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001232449.1 PFAM: Fibronectin, type III domain protein YP_001232450.1 TIGRFAM: cytochrome C family protein YP_001232451.1 PFAM: peptidase M22, glycoprotease YP_001232452.1 TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein YP_001232453.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001232454.1 PFAM: phosphatidate cytidylyltransferase YP_001232455.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_001232456.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001232457.1 Catalyzes the phosphorylation of UMP to UDP YP_001232458.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001232459.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001232460.1 PFAM: permease YjgP/YjgQ family protein YP_001232461.1 PFAM: permease YjgP/YjgQ family protein YP_001232463.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001232464.1 PFAM: cytochrome c biogenesis protein, transmembrane region YP_001232465.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001232466.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001232467.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001232469.1 PFAM: Polyprenyl synthetase YP_001232470.1 PFAM: response regulator receiver; GAF domain protein YP_001232471.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein YP_001232472.1 PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B YP_001232475.1 Enables the enzymatic reduction of mercuric ions to elemental mercury YP_001232477.1 PFAM: Radical SAM domain protein YP_001232478.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001232479.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001232480.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001232481.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001232482.1 PFAM: protein of unknown function UPF0102 YP_001232483.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001232484.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001232486.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001232487.1 TIGRFAM: 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel domain protein YP_001232488.1 PFAM: KH, type 1, domain protein YP_001232489.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001232490.1 TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54, G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_001232491.1 PFAM: SirA family protein YP_001232496.1 PFAM: glycosyl transferase, family 2 YP_001232498.1 PFAM: putative RNA methylase; methyltransferase small YP_001232500.1 PFAM: glycosyl transferase, group 1 YP_001232502.1 PFAM: glycosyl transferase, group 1 YP_001232503.1 PFAM: glycosyl transferase, family 2 YP_001232504.1 PFAM: NAD-dependent epimerase/dehydratase YP_001232505.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001232506.1 PFAM: glycosyl transferase, group 1 YP_001232508.1 PFAM: glycosyl transferase, family 2 YP_001232509.1 PFAM: polysaccharide biosynthesis protein YP_001232510.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001232511.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain YP_001232512.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001232513.1 TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain YP_001232514.1 TIGRFAM: glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase YP_001232515.1 PFAM: regulatory protein, MarR YP_001232517.1 PFAM: glycosyl transferase, family 2 YP_001232518.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001232519.1 PFAM: glycosyl transferase, family 2 YP_001232520.1 PFAM: glycosyl transferase, group 1 YP_001232521.1 PFAM: glycosyl transferase, family 9 YP_001232522.1 PFAM: glycosyl transferase, family 2 YP_001232523.1 PFAM: glycosyl transferase, group 1 YP_001232524.1 PFAM: glycosyl transferase, group 1 YP_001232525.1 PFAM: NAD-dependent epimerase/dehydratase YP_001232526.1 PFAM: glycosyl transferase, group 1 YP_001232528.1 PFAM: glycosyl transferase, family 2 YP_001232529.1 PFAM: glycosyl transferase, family 2 YP_001232530.1 PFAM: glycosyl transferase, family 2 YP_001232532.1 PFAM: glycosyl transferase, family 9 YP_001232533.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001232534.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001232535.1 PFAM: Radical SAM domain protein YP_001232536.1 PFAM: sulfotransferase YP_001232537.1 PFAM: sulfotransferase; ABC transporter related; SMART: AAA ATPase YP_001232540.1 crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is unknown YP_001232541.1 PFAM: ABC-2 type transporter YP_001232542.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein YP_001232543.1 PFAM: transposase IS3/IS911 family protein YP_001232544.1 PFAM: Integrase, catalytic region YP_001232548.1 crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is unknown YP_001232551.1 TIGRFAM: small GTP-binding protein; sulfate adenylyltransferase, large subunit; PFAM: protein synthesis factor, GTP-binding YP_001232552.1 PFAM: S23 ribosomal protein YP_001232553.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001232554.1 PFAM: adenylylsulfate kinase YP_001232555.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein YP_001232556.1 PFAM: glycosyl transferase, group 1 YP_001232557.1 PFAM: glycosyl transferase, family 2 YP_001232561.1 PFAM: NHL repeat containing protein YP_001232562.1 TIGRFAM: cytochrome C family protein YP_001232563.1 TIGRFAM: cytochrome C family protein YP_001232564.1 PFAM: cytochrome c assembly protein YP_001232565.1 PFAM: ResB family protein YP_001232567.1 TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001232568.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001232569.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: APHP domain protein YP_001232570.1 involved in de novo purine biosynthesis YP_001232572.1 TIGRFAM: selenide, water dikinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein YP_001232573.1 TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein YP_001232574.1 TIGRFAM: thiamine-phosphate pyrophosphorylase; phosphomethylpyrimidine kinase; PFAM: protein of unknown function UPF0031; thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1 YP_001232575.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001232577.1 TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase, family 35 YP_001232580.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_001232581.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_001232582.1 TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001232583.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001232584.1 PFAM: major facilitator superfamily MFS_1 YP_001232586.1 PFAM: PilT protein domain protein YP_001232588.1 PFAM: PilT protein domain protein YP_001232589.1 TIGRFAM: prevent-host-death family protein YP_001232590.1 SMART: Nucleotide binding protein, PINc YP_001232594.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001232595.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001232596.1 TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; PFAM: ABC transporter, substrate-binding protein, aliphatic sulphonates; SMART: extracellular solute-binding protein, family 3 YP_001232597.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001232598.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001232599.1 PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component YP_001232600.1 PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component YP_001232601.1 TIGRFAM: putative CoA-substrate-specific enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type YP_001232604.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001232605.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001232606.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001232607.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001232609.1 PFAM: phosphate-selective porin O and P YP_001232610.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001232611.1 PFAM: NifH/frxC-family protein YP_001232613.1 TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001232614.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component YP_001232615.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component YP_001232616.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001232617.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074 YP_001232618.1 PFAM: Smr protein/MutS2 YP_001232619.1 PFAM: OmpA/MotB domain protein YP_001232620.1 PFAM: type II secretion system protein E; General secretory system II, protein E domain protein YP_001232621.1 PFAM: HDOD; SMART: metal-dependent phosphohydrolase, HD region YP_001232623.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001232624.1 TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2 YP_001232627.1 PFAM: heat shock protein Hsp20 YP_001232628.1 PFAM: PP-loop domain protein YP_001232629.1 TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001232630.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074 YP_001232633.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001232634.1 PFAM: histidine triad (HIT) protein YP_001232635.1 PFAM: transposase IS200-family protein YP_001232636.1 TIGRFAM: apurinic endonuclease Apn1; PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease, family 2 YP_001232637.1 PFAM: protein of unknown function DUF891 YP_001232639.1 PFAM: transposase, mutator type YP_001232640.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001232641.1 PFAM: Rhodanese domain protein YP_001232642.1 PFAM: DoxX family protein YP_001232643.1 PFAM: protein of unknown function DUF205 YP_001232644.1 PFAM: type IV pilus assembly PilZ YP_001232645.1 PFAM: filamentation induced by cAMP protein Fic YP_001232647.1 PFAM: protein of unknown function DUF1568; Chromosomal replication initiator, DnaA C-terminal domain YP_001232649.1 PFAM: Integrase, catalytic region YP_001232652.1 PFAM: helix-turn-helix domain protein YP_001232653.1 TIGRFAM: sulfate adenylyltransferase, large subunit; PFAM: protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein YP_001232654.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001232655.1 TIGRFAM: adenylylsulfate reductase, thioredoxin dependent; PFAM: phosphoadenosine phosphosulfate reductase YP_001232656.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter YP_001232658.1 PFAM: transposase IS200-family protein YP_001232660.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region YP_001232661.1 PFAM: Mov34/MPN/PAD-1 family protein YP_001232662.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein YP_001232663.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein YP_001232664.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001232666.1 TIGRFAM: membrane lipoprotein lipid attachment site YP_001232667.1 PFAM: protein of unknown function DUF1425 YP_001232668.1 PFAM: Tetratricopeptide TPR_2 repeat protein YP_001232669.1 TIGRFAM: RNA polymerase sigma factor RpoH; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein YP_001232670.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001232672.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001232674.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001232678.1 PFAM: ThiJ/PfpI domain protein YP_001232680.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001232681.1 PFAM: protein of unknown function DUF1016 YP_001232685.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001232686.1 PFAM: cell division protein FtsA YP_001232687.1 PFAM: Polypeptide-transport-associated protein domain protein, FtsQ-type YP_001232688.1 TIGRFAM: D-alanine--D-alanine ligase; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; D-alanine--D-alanine ligase domain protein YP_001232689.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001232690.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001232691.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001232692.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein YP_001232693.1 TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001232694.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001232695.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001232696.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001232697.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA domain containing protein YP_001232698.1 TIGRFAM: cell division protein FtsL; PFAM: Septum formation initiator YP_001232699.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase YP_001232700.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001232703.1 PFAM: response regulator receiver; type IV pilus assembly PilZ YP_001232704.1 PFAM: protein of unknown function DUF164 YP_001232705.1 PFAM: protein of unknown function DUF34 YP_001232706.1 TIGRFAM: conserved repeat domain; PFAM: APHP domain protein; FG-GAP repeat protein YP_001232707.1 PFAM: peptidase M23B YP_001232711.1 PFAM: putative RNA methylase; THUMP domain protein YP_001232715.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001232716.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase YP_001232717.1 PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region YP_001232722.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein YP_001232725.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein YP_001232727.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase, catalytic YP_001232728.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF362 YP_001232729.1 TIGRFAM: tyrosine recombinase XerC; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein YP_001232731.1 PFAM: protein of unknown function DUF188 YP_001232732.1 PFAM: YaeQ family protein YP_001232734.1 PFAM: CoA-binding domain protein YP_001232735.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein YP_001232736.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001232737.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001232742.1 PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase YP_001232743.1 PFAM: outer membrane chaperone Skp (OmpH) YP_001232744.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001232746.1 PFAM: acetyl-CoA hydrolase/transferase YP_001232747.1 PFAM: response regulator receiver; histidine kinase A domain protein YP_001232748.1 TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001232749.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001232751.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001232752.1 catalyzes the formation of 2-oxobutanoate from L-threonine YP_001232753.1 PFAM: protein of unknown function DUF45 YP_001232754.1 TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like YP_001232756.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955 YP_001232759.1 PFAM: restriction modification system DNA specificity domain YP_001232760.1 PFAM: N-6 DNA methylase YP_001232762.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_001232763.1 TIGRFAM: exsB protein; PFAM: ExsB family protein YP_001232764.1 TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma factor RpoD domain protein; PFAM: sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 region 1.2 YP_001232765.1 TIGRFAM: DNA primase; PFAM: zinc finger, CHC2-family protein; TOPRIM domain protein; DNA primase catalytic core, N-terminal domain; SMART: Toprim sub domain protein YP_001232766.1 PFAM: Colicin V production protein YP_001232767.1 PFAM: GatB/Yqey domain protein YP_001232768.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001232769.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_001232770.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001232771.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001232772.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001232773.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001232774.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001232775.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_001232776.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001232777.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; Methyltransferase type 12 YP_001232778.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001232779.1 PFAM: protein of unknown function DUF1385 YP_001232780.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor YP_001232781.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001232782.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001232783.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001232784.1 PFAM: Class I peptide chain release factor YP_001232786.1 PFAM: protein of unknown function DUF606 YP_001232789.1 TIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B YP_001232792.1 PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein YP_001232793.1 PFAM: O-methyltransferase, family 3 YP_001232794.1 PFAM: flagellar FlbD family protein YP_001232795.1 PFAM: MotA/TolQ/ExbB proton channel YP_001232796.1 PFAM: OmpA/MotB domain protein YP_001232797.1 PFAM: transposase, mutator type YP_001232798.1 PFAM: type IV pilus assembly PilZ YP_001232799.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001232800.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001232801.1 PFAM: UDP-N-acetylglucosamine 2-epimerase YP_001232802.1 PFAM: N-acetylneuraminic acid synthase, N-terminal domain YP_001232804.1 PFAM: CBS domain containing protein; Nucleotidyl transferase YP_001232805.1 PFAM: acylneuraminate cytidylyltransferase YP_001232806.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001232807.1 PFAM: protein of unknown function DUF115 YP_001232809.1 PFAM: flagellar protein FliS YP_001232810.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein YP_001232811.1 PFAM: flagellin domain protein YP_001232812.1 binds to flagellin and appears to stabilize flagellin during flagella assembly YP_001232813.1 PFAM: carbon storage regulator YP_001232814.1 TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein YP_001232815.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein YP_001232819.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001232820.1 PFAM: flagellar L-ring protein YP_001232821.1 PFAM: SAF domain YP_001232822.1 makes up the distal portion of the flagellar basal body rod YP_001232823.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein YP_001232824.1 TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001232825.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001232826.1 PFAM: GTP-binding signal recognition particle SRP54, G- domain; SMART: AAA ATPase YP_001232827.1 membrane protein involved in the flagellar export apparatus YP_001232828.1 PFAM: surface antigen (D15) YP_001232829.1 PFAM: AAA-4 family protein YP_001232831.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001232834.1 PFAM: protein of unknown function DUF559 YP_001232835.1 TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001232836.1 PFAM: helix-turn-helix domain protein YP_001232838.1 SMART: helicase c2 YP_001232842.1 PFAM: protein of unknown function DUF1121 YP_001232843.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001232844.1 PFAM: protein of unknown function DUF163 YP_001232845.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein YP_001232846.1 TIGRFAM: cytidyltransferase-related domain; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase YP_001232847.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001232848.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001232850.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein YP_001232851.1 PFAM: phosphate transporter YP_001232852.1 PFAM: protein of unknown function DUF47 YP_001232853.1 TIGRFAM: putative undecaprenol kinase; PFAM: Bacitracin resistance protein BacA YP_001232854.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001232855.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001232857.1 PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 YP_001232858.1 PFAM: protein of unknown function DUF898, transmembrane YP_001232859.1 PFAM: peptidase M48, Ste24p YP_001232860.1 SMART: AAA ATPase YP_001232863.1 PFAM: protein of unknown function DUF1526 YP_001232864.1 PFAM: filamentation induced by cAMP protein Fic YP_001232867.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001232868.1 PFAM: histidine triad (HIT) protein YP_001232869.1 PFAM: Rubrerythrin YP_001232870.1 PFAM: O-methyltransferase, family 2; Methyltransferase type 12 YP_001232873.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001232874.1 PFAM: CMP/dCMP deaminase, zinc-binding YP_001232875.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001232876.1 PFAM: TrkA-N domain protein; TrkA-C domain protein; Ion transport 2 domain protein YP_001232877.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001232878.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_001232879.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001232880.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001232881.1 PFAM: DNA polymerase, beta domain protein region YP_001232882.1 PFAM: protein of unknown function DUF86 YP_001232883.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001232884.1 PFAM: MCP methyltransferase, CheR-type; TPR repeat-containing protein; response regulator receiver; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001232885.1 PFAM: CheW domain protein YP_001232886.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001232887.1 PFAM: response regulator receiver; CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein YP_001232888.1 PFAM: CheB methylesterase; response regulator receiver YP_001232889.1 PFAM: response regulator receiver YP_001232890.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001232891.1 PFAM: CopG domain protein DNA-binding domain protein YP_001232892.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; hydrogenase large subunit domain protein; Fe-S cluster domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001232894.1 PFAM: transglutaminase domain protein YP_001232895.1 TIGRFAM: cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001232896.1 TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein YP_001232898.1 catalyzes the ATP-dependent transport of cobalt YP_001232899.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001232900.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_001232901.1 PFAM: Phosphoglycerate mutase YP_001232902.1 TIGRFAM: cobalamin 5'-phosphate synthase; PFAM: cobalamin-5-phosphate synthase CobS YP_001232903.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001232904.1 PFAM: cobalbumin biosynthesis enzyme YP_001232905.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001232906.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; HDOD; SMART: metal-dependent phosphohydrolase, HD region YP_001232907.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001232908.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001232909.1 TIGRFAM: alpha-glucan phosphorylase; PFAM: glycosyl transferase, family 35 YP_001232912.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001232913.1 TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein YP_001232914.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ, family 3 YP_001232915.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001232917.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein YP_001232918.1 PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM YP_001232919.1 PFAM: flagellar basal body-associated protein FliL YP_001232920.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein YP_001232921.1 TIGRFAM: flagellar operon protein YP_001232922.1 PFAM: flagellar hook capping protein YP_001232923.1 PFAM: flagellar hook-length control protein YP_001232925.1 TIGRFAM: flagellar export protein FliJ YP_001232926.1 TIGRFAM: ATPase, FliI/YscN family; flagellar protein export ATPase FliI; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; SMART: AAA ATPase YP_001232928.1 PFAM: flagellar motor switch protein FliG YP_001232929.1 TIGRFAM: flagellar M-ring protein FliF; PFAM: secretory protein YscJ/FliF family protein; Flagellar M-ring C-terminal domain protein YP_001232930.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE YP_001232931.1 TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein YP_001232932.1 TIGRFAM: flagellar basal-body rod protein FlgB YP_001232933.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein YP_001232934.1 PFAM: response regulator receiver YP_001232936.1 PFAM: response regulator receiver YP_001232937.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein YP_001232938.1 PFAM: chemotaxis sensory transducer YP_001232939.1 PFAM: regulatory protein, ArsR YP_001232940.1 PFAM: Rhodanese domain protein YP_001232941.1 PFAM: beta-lactamase domain protein YP_001232943.1 TIGRFAM: C_GCAxxG_C_C family protein YP_001232944.1 PFAM: acriflavin resistance protein YP_001232945.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001232946.1 PFAM: outer membrane efflux protein YP_001232947.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001232948.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001232949.1 TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I) YP_001232950.1 PFAM: NADH-ubiquinone oxidoreductase, chain 4L YP_001232951.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 YP_001232952.1 TIGRFAM: NADH-quinone oxidoreductase, chain I; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001232953.1 PFAM: respiratory-chain NADH dehydrogenase, subunit 1 YP_001232954.1 PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001232955.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit YP_001232956.1 PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit YP_001232957.1 TIGRFAM: NADH dehydrogenase I, D subunit; PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa YP_001232958.1 TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone), 30 kDa subunit YP_001232959.1 TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001232960.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_001232961.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001232964.1 TIGRFAM: ATP synthase F0, A subunit; PFAM: H+-transporting two-sector ATPase, A subunit YP_001232965.1 TIGRFAM: ATP synthase F0, C subunit; PFAM: H+-transporting two-sector ATPase, C subunit YP_001232966.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_001232967.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein YP_001232968.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001232969.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein YP_001232970.1 TIGRFAM: PAS sensor protein; PFAM: histidine kinase, HAMP region domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001232972.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001232973.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease YP_001232974.1 PFAM: H+-transporting two-sector ATPase, B/B' subunit YP_001232975.1 PFAM: H+-transporting two-sector ATPase, B/B' subunit YP_001232976.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001232977.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001232978.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the gamma chain is a regulatory subunit YP_001232979.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001232980.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex YP_001232981.1 PFAM: protein of unknown function UPF0153 YP_001232983.1 PFAM: metal-dependent phosphohydrolase, HD sub domain YP_001232984.1 TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA YP_001232985.1 PFAM: glycosyl transferase, family 51 YP_001232986.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001232987.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein YP_001232988.1 PFAM: thiamine biosynthesis protein YP_001232989.1 PFAM: General secretory system II, protein E domain protein YP_001232990.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001232991.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001232992.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase YP_001232993.1 PFAM: Semialdehyde dehydrogenase, NAD - binding; oxidoreductase domain protein; Oxidoreductase, C-terminal domain YP_001232994.1 PFAM: NDP-hexose 2,3-dehydratase YP_001232995.1 PFAM: glycosyl transferase, family 2 YP_001232997.1 TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein YP_001232998.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_001232999.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein YP_001233000.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001233001.1 PFAM: Radical SAM domain protein YP_001233002.1 TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II YP_001233003.1 PFAM: HRDC domain protein; 3'-5' exonuclease YP_001233005.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001233006.1 TIGRFAM: ribosomal protein L11 methyltransferase; PFAM: methyltransferase small; ribosomal L11 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001233007.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001233008.1 PFAM: protein of unknown function DUF299 YP_001233009.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001233010.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein YP_001233011.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001233012.1 TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001233014.1 PFAM: phospholipid/glycerol acyltransferase YP_001233015.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001233016.1 PFAM: AAA-4 family protein YP_001233017.1 PFAM: protein of unknown function DUF450 YP_001233018.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001233022.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001233023.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001233024.1 PFAM: PrkA serine kinase; PrkA AAA domain protein YP_001233027.1 SMART: PrkA AAA domain protein YP_001233028.1 PFAM: K+ potassium transporter YP_001233029.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001233030.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001233033.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001233035.1 PFAM: protein of unknown function DUF395, YeeE/YedE YP_001233036.1 PFAM: thioesterase superfamily protein YP_001233037.1 PFAM: glutamate-ammonia ligase adenylyltransferase YP_001233038.1 TIGRFAM: putative translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related YP_001233039.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001233040.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001233041.1 TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; PFAM: Glu-tRNAGln amidotransferase, C subunit YP_001233042.1 PFAM: UvrD/REP helicase YP_001233043.1 TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_001233044.1 PFAM: conserved hypothetical protein 103 YP_001233045.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001233046.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein YP_001233047.1 PFAM: Roadblock/LC7 family protein YP_001233049.1 PFAM: OmpA/MotB domain protein YP_001233050.1 PFAM: protein of unknown function DUF748 YP_001233051.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001233052.1 PFAM: GCN5-related N-acetyltransferase YP_001233053.1 PFAM: peptidase M20; peptidase dimerisation domain protein YP_001233056.1 PFAM: putative carbohydrate binding; glycosyltransferase 36; glycosyltransferase 36 associated YP_001233061.1 PFAM: Integrase, catalytic region YP_001233062.1 PFAM: regulatory protein, IclR YP_001233064.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase YP_001233065.1 TIGRFAM: succinyl-CoA synthetase, beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein YP_001233068.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001233070.1 PFAM: Thiolase YP_001233071.1 TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001233072.1 TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001233073.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein YP_001233075.1 PFAM: Hydantoinase B/oxoprolinase YP_001233076.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein YP_001233078.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein YP_001233079.1 PFAM: helix-turn-helix- domain containing protein, AraC type; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; SMART: AAA ATPase YP_001233080.1 PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Cache, type 2 domain protein YP_001233081.1 PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein YP_001233083.1 PFAM: Integrase, catalytic region YP_001233085.1 PFAM: aldo/keto reductase YP_001233086.1 PFAM: Carboxymuconolactone decarboxylase; Cupin 2, conserved barrel domain protein YP_001233089.1 PFAM: aldo/keto reductase YP_001233090.1 PFAM: aldo/keto reductase YP_001233091.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein YP_001233092.1 PFAM: Rhodanese domain protein YP_001233093.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001233094.1 TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001233095.1 TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter related YP_001233096.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001233097.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III YP_001233098.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001233100.1 PFAM: cytochrome c assembly protein YP_001233101.1 TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase YP_001233102.1 PFAM: amino acid-binding ACT domain protein YP_001233104.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955 YP_001233105.1 PFAM: type III restriction enzyme, res subunit YP_001233106.1 PFAM: DNA methylase N-4/N-6 domain protein YP_001233108.1 PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase YP_001233109.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase YP_001233112.1 TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase YP_001233113.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n YP_001233116.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE YP_001233117.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001233118.1 PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases-like YP_001233119.1 PFAM: protein of unknown function DUF6, transmembrane YP_001233122.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001233123.1 PFAM: histone family protein DNA-binding protein YP_001233125.1 PFAM: pyruvate kinase YP_001233126.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase YP_001233127.1 PFAM: Auxin Efflux Carrier YP_001233128.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001233129.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease YP_001233130.1 PFAM: UBA/THIF-type NAD/FAD binding protein YP_001233131.1 PFAM: Rubrerythrin YP_001233133.1 PFAM: Lytic transglycosylase, catalytic YP_001233134.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001233135.1 PFAM: CheW domain protein YP_001233136.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein YP_001233137.1 PFAM: MCP methyltransferase, CheR-type YP_001233138.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; HDOD; SMART: metal-dependent phosphohydrolase, HD region YP_001233139.1 PFAM: CheB methylesterase; response regulator receiver YP_001233142.1 TIGRFAM: methyltransferase GidB; PFAM: glucose inhibited division protein YP_001233143.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001233144.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001233145.1 PFAM: 60 kDa inner membrane insertion protein YP_001233146.1 PFAM: protein of unknown function DUF37 YP_001233147.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001233148.1 in Escherichia coli transcription of this gene is enhanced by polyamines