-- dump date 20140619_104054 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type NP_872636.1 33151283 1490023 296..2188 1 NC_002940.2 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 2188 gidA 1490023 gidA Haemophilus ducreyi 35000HP tRNA uridine 5-carboxymethylaminomethyl modification protein GidA NP_872636.1 296 D 233412 CDS NP_872637.1 33151284 1490024 2293..2904 1 NC_002940.2 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 2904 gidB 1490024 gidB Haemophilus ducreyi 35000HP 16S rRNA methyltransferase GidB NP_872637.1 2293 D 233412 CDS NP_872638.1 33151285 1490025 3220..3603 1 NC_002940.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 3603 1490025 HD0003 Haemophilus ducreyi 35000HP F0F1 ATP synthase subunit I NP_872638.1 3220 D 233412 CDS NP_872639.1 33151286 1490026 3629..4417 1 NC_002940.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 4417 atpB 1490026 atpB Haemophilus ducreyi 35000HP ATP synthase F0F1 subunit A NP_872639.1 3629 D 233412 CDS NP_872640.1 33151287 1490027 4538..4792 1 NC_002940.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 4792 atpE 1490027 atpE Haemophilus ducreyi 35000HP ATP synthase F0F1 subunit C NP_872640.1 4538 D 233412 CDS NP_872641.1 33151288 1490028 4846..5316 1 NC_002940.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 5316 atpF 1490028 atpF Haemophilus ducreyi 35000HP ATP synthase F0F1 subunit B NP_872641.1 4846 D 233412 CDS NP_872642.1 33151289 1490029 5330..5863 1 NC_002940.2 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 5863 atpH 1490029 atpH Haemophilus ducreyi 35000HP ATP synthase F0F1 subunit delta NP_872642.1 5330 D 233412 CDS NP_872643.1 33151290 1490030 5876..7417 1 NC_002940.2 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 7417 atpA 1490030 atpA Haemophilus ducreyi 35000HP ATP synthase F0F1 subunit alpha NP_872643.1 5876 D 233412 CDS NP_872644.1 33151291 1490031 7441..8307 1 NC_002940.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 8307 atpG 1490031 atpG Haemophilus ducreyi 35000HP ATP synthase F0F1 subunit gamma NP_872644.1 7441 D 233412 CDS NP_872645.1 33151292 1490032 8323..9696 1 NC_002940.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 9696 atpD 1490032 atpD Haemophilus ducreyi 35000HP ATP synthase F0F1 subunit beta NP_872645.1 8323 D 233412 CDS NP_872646.1 33151293 1490033 9736..10155 1 NC_002940.2 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 10155 atpC 1490033 atpC Haemophilus ducreyi 35000HP ATP synthase F0F1 subunit epsilon NP_872646.1 9736 D 233412 CDS NP_872647.1 33151294 1490043 16486..17379 1 NC_002940.2 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 17379 xerD 1490043 xerD Haemophilus ducreyi 35000HP site-specific tyrosine recombinase XerD NP_872647.1 16486 D 233412 CDS NP_872648.1 33151295 1490044 complement(17376..18662) 1 NC_002940.2 cell-cycle protein MesJ 18662 mesJ 1490044 mesJ Haemophilus ducreyi 35000HP cell-cycle protein MesJ NP_872648.1 17376 R 233412 CDS NP_872649.1 33151296 1490045 18773..20233 1 NC_002940.2 TldD protein 20233 tldD 1490045 tldD Haemophilus ducreyi 35000HP TldD protein NP_872649.1 18773 D 233412 CDS NP_872650.1 33151297 1490046 20276..21157 1 NC_002940.2 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 21157 prmA 1490046 prmA Haemophilus ducreyi 35000HP 50S ribosomal protein L11 methyltransferase NP_872650.1 20276 D 233412 CDS NP_872651.1 33151298 1490049 complement(23154..23306) 1 NC_002940.2 hypothetical protein 23306 1490049 HD0022 Haemophilus ducreyi 35000HP hypothetical protein NP_872651.1 23154 R 233412 CDS NP_872652.1 33151299 1490050 23295..24359 1 NC_002940.2 transport system permease 24359 1490050 HD0023 Haemophilus ducreyi 35000HP transport system permease NP_872652.1 23295 D 233412 CDS NP_872653.1 33151300 1490051 24359..24733 1 NC_002940.2 CrcB protein 24733 crcB 1490051 crcB Haemophilus ducreyi 35000HP CrcB protein NP_872653.1 24359 D 233412 CDS NP_872654.1 33151301 1490052 complement(24825..26168) 1 NC_002940.2 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 26168 dcuB1 1490052 dcuB1 Haemophilus ducreyi 35000HP anaerobic C4-dicarboxylate transporter NP_872654.1 24825 R 233412 CDS NP_872655.1 33151302 1490053 26348..27172 1 NC_002940.2 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 27172 dapF 1490053 dapF Haemophilus ducreyi 35000HP diaminopimelate epimerase NP_872655.1 26348 D 233412 CDS NP_872656.1 33151303 1490054 complement(27251..28234) 1 NC_002940.2 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 28234 genX 1490054 genX Haemophilus ducreyi 35000HP lysyl-tRNA synthetase NP_872656.1 27251 R 233412 CDS NP_872657.1 33151304 1490055 28584..30383 1 NC_002940.2 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 30383 frdA 1490055 frdA Haemophilus ducreyi 35000HP fumarate reductase flavoprotein subunit NP_872657.1 28584 D 233412 CDS NP_872658.1 33151305 1490056 30396..31130 1 NC_002940.2 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 31130 frdB 1490056 frdB Haemophilus ducreyi 35000HP fumarate reductase iron-sulfur subunit NP_872658.1 30396 D 233412 CDS NP_872659.1 33151306 1490057 31139..31525 1 NC_002940.2 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 31525 frdC 1490057 frdC Haemophilus ducreyi 35000HP fumarate reductase subunit C NP_872659.1 31139 D 233412 CDS NP_872660.1 33151307 1490058 31535..31879 1 NC_002940.2 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 31879 frdD 1490058 frdD Haemophilus ducreyi 35000HP fumarate reductase subunit D NP_872660.1 31535 D 233412 CDS NP_872661.1 33151308 1490059 32032..32130 1 NC_002940.2 hypothetical protein 32130 1490059 HD0035 Haemophilus ducreyi 35000HP hypothetical protein NP_872661.1 32032 D 233412 CDS NP_872662.1 33151309 1490060 32231..33484 1 NC_002940.2 diaminopimelate decarboxylase 33484 lysA 1490060 lysA Haemophilus ducreyi 35000HP diaminopimelate decarboxylase NP_872662.1 32231 D 233412 CDS NP_872663.1 33151310 1490061 33596..35410 1 NC_002940.2 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 35410 chuW 1490061 chuW Haemophilus ducreyi 35000HP coproporphyrinogen III oxidase NP_872663.1 33596 D 233412 CDS NP_872664.1 33151311 1490062 35412..36011 1 NC_002940.2 hypothetical protein 36011 1490062 HD0038 Haemophilus ducreyi 35000HP hypothetical protein NP_872664.1 35412 D 233412 CDS NP_872665.1 33151312 1490063 complement(36101..37459) 1 NC_002940.2 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 37459 trmE 1490063 trmE Haemophilus ducreyi 35000HP tRNA modification GTPase TrmE NP_872665.1 36101 R 233412 CDS NP_872666.1 33151313 1490064 complement(37610..39220) 1 NC_002940.2 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 39220 yidC 1490064 yidC Haemophilus ducreyi 35000HP inner membrane protein translocase component YidC NP_872666.1 37610 R 233412 CDS NP_872667.1 33151314 1490065 complement(39217..39312) 1 NC_002940.2 hypothetical protein 39312 1490065 HD0041 Haemophilus ducreyi 35000HP hypothetical protein NP_872667.1 39217 R 233412 CDS NP_872668.1 33151315 1490066 complement(39364..39795) 1 NC_002940.2 hypothetical protein 39795 1490066 HD0042 Haemophilus ducreyi 35000HP hypothetical protein NP_872668.1 39364 R 233412 CDS NP_872669.1 33151316 1490067 39765..39884 1 NC_002940.2 hypothetical protein 39884 1490067 HD0043 Haemophilus ducreyi 35000HP hypothetical protein NP_872669.1 39765 D 233412 CDS NP_872670.1 33151317 1490068 complement(39951..40070) 1 NC_002940.2 hypothetical protein 40070 1490068 HD0044 Haemophilus ducreyi 35000HP hypothetical protein NP_872670.1 39951 R 233412 CDS NP_872671.1 33151318 1490069 40269..41480 1 NC_002940.2 major outer membrane protein 41480 momp 1490069 momp Haemophilus ducreyi 35000HP major outer membrane protein NP_872671.1 40269 D 233412 CDS NP_872672.1 33151319 1490070 41761..42984 1 NC_002940.2 major outer membrane protein, OmpA2 42984 ompA2 1490070 ompA2 Haemophilus ducreyi 35000HP major outer membrane protein, OmpA2 NP_872672.1 41761 D 233412 CDS NP_872673.1 33151320 1490071 43024..43116 1 NC_002940.2 hypothetical protein 43116 1490071 HD0047 Haemophilus ducreyi 35000HP hypothetical protein NP_872673.1 43024 D 233412 CDS NP_872674.1 33151321 1490072 43035..43130 1 NC_002940.2 hypothetical protein 43130 1490072 HD0048 Haemophilus ducreyi 35000HP hypothetical protein NP_872674.1 43035 D 233412 CDS NP_872675.1 33151322 1490073 43187..43912 1 NC_002940.2 1-acyl-sn-glycerol-3-phosphate acyltransferase 43912 plsC 1490073 plsC Haemophilus ducreyi 35000HP 1-acyl-sn-glycerol-3-phosphate acyltransferase NP_872675.1 43187 D 233412 CDS NP_872676.1 33151323 1490074 43919..45337 1 NC_002940.2 SufI protein 45337 sufI 1490074 sufI Haemophilus ducreyi 35000HP SufI protein NP_872676.1 43919 D 233412 CDS NP_872677.1 33151324 1490075 45469..46422 1 NC_002940.2 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 46422 accA 1490075 accA Haemophilus ducreyi 35000HP acetyl-CoA carboxylase carboxyltransferase subunit alpha NP_872677.1 45469 D 233412 CDS NP_872678.1 33151325 1490076 complement(46419..46514) 1 NC_002940.2 hypothetical protein 46514 1490076 HD0052 Haemophilus ducreyi 35000HP hypothetical protein NP_872678.1 46419 R 233412 CDS NP_872679.1 33151326 1490077 complement(46609..47808) 1 NC_002940.2 hypothetical protein 47808 1490077 HD0053 Haemophilus ducreyi 35000HP hypothetical protein NP_872679.1 46609 R 233412 CDS NP_872680.1 33151327 1490078 complement(47920..49104) 1 NC_002940.2 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 49104 tuf 1490078 tuf Haemophilus ducreyi 35000HP elongation factor Tu NP_872680.1 47920 R 233412 CDS NP_872681.1 33151328 1490082 49672..49767 1 NC_002940.2 hypothetical protein 49767 1490082 HD0055 Haemophilus ducreyi 35000HP hypothetical protein NP_872681.1 49672 D 233412 CDS NP_872682.1 33151329 1490083 49866..50816 1 NC_002940.2 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 50816 coaA 1490083 coaA Haemophilus ducreyi 35000HP pantothenate kinase NP_872682.1 49866 D 233412 CDS NP_872683.1 33151330 1490084 50893..51432 1 NC_002940.2 thiol:disulfide interchange protein DsbE 51432 dsbE1 1490084 dsbE1 Haemophilus ducreyi 35000HP thiol:disulfide interchange protein DsbE NP_872683.1 50893 D 233412 CDS NP_872684.1 33151331 1490086 52812..53396 1 NC_002940.2 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 53396 mogA 1490086 mogA Haemophilus ducreyi 35000HP molybdenum cofactor biosynthesis protein MogA NP_872684.1 52812 D 233412 CDS NP_872685.1 33151332 1490087 53408..53746 1 NC_002940.2 nitrogen regulatory protein P-II 53746 glnB 1490087 glnB Haemophilus ducreyi 35000HP nitrogen regulatory protein P-II NP_872685.1 53408 D 233412 CDS NP_872686.1 33151333 1490088 53810..54295 1 NC_002940.2 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 54295 lspA 1490088 lspA Haemophilus ducreyi 35000HP lipoprotein signal peptidase NP_872686.1 53810 D 233412 CDS NP_872687.1 33151334 1490089 54296..55240 1 NC_002940.2 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 55240 ispH 1490089 ispH Haemophilus ducreyi 35000HP 4-hydroxy-3-methylbut-2-enyl diphosphate reductase NP_872687.1 54296 D 233412 CDS NP_872688.1 33151335 1490090 55240..55488 1 NC_002940.2 hypothetical protein 55488 1490090 HD0065 Haemophilus ducreyi 35000HP hypothetical protein NP_872688.1 55240 D 233412 CDS NP_872689.1 33151336 1490091 complement(55564..56937) 1 NC_002940.2 hypothetical protein 56937 1490091 HD0066 Haemophilus ducreyi 35000HP hypothetical protein NP_872689.1 55564 R 233412 CDS NP_872690.1 33151337 1490092 complement(57151..57723) 1 NC_002940.2 fine tangled pili major subunit 57723 ftpA 1490092 ftpA Haemophilus ducreyi 35000HP fine tangled pili major subunit NP_872690.1 57151 R 233412 CDS NP_872691.1 33151338 1490093 complement(57947..60142) 1 NC_002940.2 hypothetical protein 60142 1490093 HD0069 Haemophilus ducreyi 35000HP hypothetical protein NP_872691.1 57947 R 233412 CDS NP_872692.1 33151339 1490094 complement(60447..60557) 1 NC_002940.2 hypothetical protein 60557 1490094 HD0070 Haemophilus ducreyi 35000HP hypothetical protein NP_872692.1 60447 R 233412 CDS NP_872693.1 33151340 1490095 60848..61375 1 NC_002940.2 ferredoxin-type protein NapF 61375 napF 1490095 napF Haemophilus ducreyi 35000HP ferredoxin-type protein NapF NP_872693.1 60848 D 233412 CDS NP_872694.1 33151341 1490096 61417..61680 1 NC_002940.2 periplasmic nitrate reductase subunit NapD 61680 napD 1490096 napD Haemophilus ducreyi 35000HP periplasmic nitrate reductase subunit NapD NP_872694.1 61417 D 233412 CDS NP_872695.1 33151342 1490097 61718..64201 1 NC_002940.2 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 64201 napA 1490097 napA Haemophilus ducreyi 35000HP nitrate reductase catalytic subunit NP_872695.1 61718 D 233412 CDS NP_872696.1 33151343 1490098 64322..65221 1 NC_002940.2 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 65221 napG 1490098 napG Haemophilus ducreyi 35000HP quinol dehydrogenase periplasmic component NP_872696.1 64322 D 233412 CDS NP_872697.1 33151344 1490099 65221..66114 1 NC_002940.2 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 66114 napH 1490099 napH Haemophilus ducreyi 35000HP quinol dehydrogenase membrane component NP_872697.1 65221 D 233412 CDS NP_872698.1 33151345 1490100 66189..66629 1 NC_002940.2 cytochrome c-type protein 66629 napB 1490100 napB Haemophilus ducreyi 35000HP cytochrome c-type protein NP_872698.1 66189 D 233412 CDS NP_872699.1 33151346 1490101 66641..67258 1 NC_002940.2 cytochrome c-type protein 67258 napC 1490101 napC Haemophilus ducreyi 35000HP cytochrome c-type protein NP_872699.1 66641 D 233412 CDS NP_872700.1 33151347 1490102 67395..68429 1 NC_002940.2 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 68429 murB 1490102 murB Haemophilus ducreyi 35000HP UDP-N-acetylenolpyruvoylglucosamine reductase NP_872700.1 67395 D 233412 CDS NP_872701.1 33151348 1490103 68356..69192 1 NC_002940.2 bifunctional; biotin--(acetyl-CoA-carboxylase) synthetase; biotin operon represssor 69192 birA 1490103 birA Haemophilus ducreyi 35000HP biotin operon represssor NP_872701.1 68356 D 233412 CDS NP_872702.1 33151349 1490104 69227..69352 1 NC_002940.2 hypothetical protein 69352 1490104 HD0083 Haemophilus ducreyi 35000HP hypothetical protein NP_872702.1 69227 D 233412 CDS NP_872703.1 33151350 1490105 69429..70574 1 NC_002940.2 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 70574 lldD 1490105 lldD Haemophilus ducreyi 35000HP L-lactate dehydrogenase NP_872703.1 69429 D 233412 CDS NP_872704.1 33151351 1490106 complement(70943..71167) 1 NC_002940.2 hypothetical protein 71167 1490106 HD0085 Haemophilus ducreyi 35000HP hypothetical protein NP_872704.1 70943 R 233412 CDS NP_872705.1 33151352 1490107 71207..72166 1 NC_002940.2 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 72166 rpoH 1490107 rpoH Haemophilus ducreyi 35000HP RNA polymerase factor sigma-32 NP_872705.1 71207 D 233412 CDS NP_872706.1 33151353 1490108 72188..72292 1 NC_002940.2 hypothetical protein 72292 1490108 HD0087 Haemophilus ducreyi 35000HP hypothetical protein NP_872706.1 72188 D 233412 CDS NP_872707.1 33151354 1490109 complement(72533..73234) 1 NC_002940.2 transcriptional regulator 73234 1490109 HD0089 Haemophilus ducreyi 35000HP transcriptional regulator NP_872707.1 72533 R 233412 CDS NP_872708.1 33151355 1490110 73434..73694 1 NC_002940.2 DNA-binding protein 73694 ner 1490110 ner Haemophilus ducreyi 35000HP DNA-binding protein NP_872708.1 73434 D 233412 CDS NP_872709.1 33151356 1490112 75767..76684 1 NC_002940.2 Mu phage DNA transposition protein B 76684 1490112 HD0095 Haemophilus ducreyi 35000HP Mu phage DNA transposition protein B NP_872709.1 75767 D 233412 CDS NP_872710.1 33151357 1490113 76684..76917 1 NC_002940.2 hypothetical protein 76917 1490113 HD0096 Haemophilus ducreyi 35000HP hypothetical protein NP_872710.1 76684 D 233412 CDS NP_872711.1 33151358 1490114 76930..77547 1 NC_002940.2 hypothetical protein 77547 1490114 HD0097 Haemophilus ducreyi 35000HP hypothetical protein NP_872711.1 76930 D 233412 CDS NP_872712.1 33151359 1490115 77540..77776 1 NC_002940.2 hypothetical protein 77776 1490115 HD0098 Haemophilus ducreyi 35000HP hypothetical protein NP_872712.1 77540 D 233412 CDS NP_872713.1 33151360 1490116 77879..77974 1 NC_002940.2 hypothetical protein 77974 1490116 HD0099 Haemophilus ducreyi 35000HP hypothetical protein NP_872713.1 77879 D 233412 CDS NP_872714.1 33151361 1490117 78034..78168 1 NC_002940.2 hypothetical protein 78168 1490117 HD0100 Haemophilus ducreyi 35000HP hypothetical protein NP_872714.1 78034 D 233412 CDS NP_872715.1 33151362 1490118 78171..78389 1 NC_002940.2 hypothetical protein 78389 1490118 HD0101 Haemophilus ducreyi 35000HP hypothetical protein NP_872715.1 78171 D 233412 CDS NP_872716.1 33151363 1490119 78392..78595 1 NC_002940.2 hypothetical protein 78595 1490119 HD0102 Haemophilus ducreyi 35000HP hypothetical protein NP_872716.1 78392 D 233412 CDS NP_872717.1 33151364 1490120 78592..78927 1 NC_002940.2 hypothetical protein 78927 1490120 HD0103 Haemophilus ducreyi 35000HP hypothetical protein NP_872717.1 78592 D 233412 CDS NP_872718.1 33151365 1490121 78936..79229 1 NC_002940.2 hypothetical protein 79229 1490121 HD0104 Haemophilus ducreyi 35000HP hypothetical protein NP_872718.1 78936 D 233412 CDS NP_872719.1 33151366 1490122 79231..79968 1 NC_002940.2 hypothetical protein 79968 1490122 HD0105 Haemophilus ducreyi 35000HP hypothetical protein NP_872719.1 79231 D 233412 CDS NP_872720.1 33151367 1490123 79968..80243 1 NC_002940.2 hypothetical protein 80243 1490123 HD0106 Haemophilus ducreyi 35000HP hypothetical protein NP_872720.1 79968 D 233412 CDS NP_872721.1 33151368 1490124 80321..80791 1 NC_002940.2 hypothetical protein 80791 1490124 HD0107 Haemophilus ducreyi 35000HP hypothetical protein NP_872721.1 80321 D 233412 CDS NP_872722.1 33151369 1490125 80773..81141 1 NC_002940.2 hypothetical protein 81141 1490125 HD0108 Haemophilus ducreyi 35000HP hypothetical protein NP_872722.1 80773 D 233412 CDS NP_872723.1 33151370 1490126 complement(81037..81471) 1 NC_002940.2 hypothetical protein 81471 1490126 HD0109 Haemophilus ducreyi 35000HP hypothetical protein NP_872723.1 81037 R 233412 CDS NP_872724.1 33151371 1490127 81119..81583 1 NC_002940.2 Mu-like phage E16 protein 81583 1490127 HD0110 Haemophilus ducreyi 35000HP Mu-like phage E16 protein NP_872724.1 81119 D 233412 CDS NP_872725.1 33151372 1490128 81559..81915 1 NC_002940.2 Mu-like phage C protein, positive regulator of late transcription 81915 1490128 HD0111 Haemophilus ducreyi 35000HP Mu-like phage C protein, positive regulator of late transcription NP_872725.1 81559 D 233412 CDS NP_872726.1 33151373 1490129 82023..82544 1 NC_002940.2 N-acetylmuramoyl-L-alanine amidase 82544 1490129 HD0112 Haemophilus ducreyi 35000HP N-acetylmuramoyl-L-alanine amidase NP_872726.1 82023 D 233412 CDS NP_872727.1 33151374 1490130 82549..82767 1 NC_002940.2 hypothetical protein 82767 1490130 HD0113 Haemophilus ducreyi 35000HP hypothetical protein NP_872727.1 82549 D 233412 CDS NP_872728.1 33151375 1490131 82777..83007 1 NC_002940.2 hypothetical protein 83007 1490131 HD0114 Haemophilus ducreyi 35000HP hypothetical protein NP_872728.1 82777 D 233412 CDS NP_872729.1 33151376 1490132 83010..83294 1 NC_002940.2 hypothetical protein 83294 1490132 HD0115 Haemophilus ducreyi 35000HP hypothetical protein NP_872729.1 83010 D 233412 CDS NP_872730.1 33151377 1490133 complement(83355..84017) 1 NC_002940.2 hypothetical protein 84017 1490133 HD0119 Haemophilus ducreyi 35000HP hypothetical protein NP_872730.1 83355 R 233412 CDS NP_872731.1 33151378 1490134 83414..83644 1 NC_002940.2 hypothetical protein 83644 1490134 HD0117 Haemophilus ducreyi 35000HP hypothetical protein NP_872731.1 83414 D 233412 CDS NP_872732.1 33151379 1490135 83641..83976 1 NC_002940.2 Mu-like phage gp25 83976 1490135 HD0118 Haemophilus ducreyi 35000HP Mu-like phage gp25 NP_872732.1 83641 D 233412 CDS NP_872733.1 33151380 1490136 84064..84279 1 NC_002940.2 Mu-like phage gp26 84279 1490136 HD0120 Haemophilus ducreyi 35000HP Mu-like phage gp26 NP_872733.1 84064 D 233412 CDS NP_872734.1 33151381 1490137 84302..84871 1 NC_002940.2 Mu-like phage gp27 84871 1490137 HD0121 Haemophilus ducreyi 35000HP Mu-like phage gp27 NP_872734.1 84302 D 233412 CDS NP_872735.1 33151382 1490138 84871..86430 1 NC_002940.2 Mu-like phage gp28 86430 1490138 HD0123 Haemophilus ducreyi 35000HP Mu-like phage gp28 NP_872735.1 84871 D 233412 CDS NP_872736.1 33151383 1490139 86434..88038 1 NC_002940.2 Mu-like phage gp29 88038 1490139 HD0124 Haemophilus ducreyi 35000HP Mu-like phage gp29 NP_872736.1 86434 D 233412 CDS NP_872737.1 33151384 1490141 89500..89943 1 NC_002940.2 Mu-like phage G protein 1 89943 1490141 HD0127 Haemophilus ducreyi 35000HP Mu-like phage G protein 1 NP_872737.1 89500 D 233412 CDS NP_872738.1 33151385 1490142 complement(89897..89989) 1 NC_002940.2 hypothetical protein 89989 1490142 HD0128 Haemophilus ducreyi 35000HP hypothetical protein NP_872738.1 89897 R 233412 CDS NP_872739.1 33151386 1490144 91186..92097 1 NC_002940.2 hypothetical protein 92097 1490144 HD0132 Haemophilus ducreyi 35000HP hypothetical protein NP_872739.1 91186 D 233412 CDS NP_872740.1 33151387 1490145 92172..92552 1 NC_002940.2 hypothetical protein 92552 1490145 HD0133 Haemophilus ducreyi 35000HP hypothetical protein NP_872740.1 92172 D 233412 CDS NP_872741.1 33151388 1490146 92552..92971 1 NC_002940.2 Mu-like prophage protein GP36 92971 1490146 HD0134 Haemophilus ducreyi 35000HP Mu-like prophage protein GP36 NP_872741.1 92552 D 233412 CDS NP_872742.1 33151389 1490147 92971..93624 1 NC_002940.2 hypothetical protein 93624 1490147 HD0135 Haemophilus ducreyi 35000HP hypothetical protein NP_872742.1 92971 D 233412 CDS NP_872743.1 33151390 1490148 93614..94354 1 NC_002940.2 hypothetical protein 94354 1490148 HD0136 Haemophilus ducreyi 35000HP hypothetical protein NP_872743.1 93614 D 233412 CDS NP_872744.1 33151391 1490149 94400..94828 1 NC_002940.2 hypothetical protein 94828 1490149 HD0137 Haemophilus ducreyi 35000HP hypothetical protein NP_872744.1 94400 D 233412 CDS NP_872745.1 33151392 1490150 94837..95016 1 NC_002940.2 hypothetical protein 95016 1490150 HD0138 Haemophilus ducreyi 35000HP hypothetical protein NP_872745.1 94837 D 233412 CDS NP_872746.1 33151393 1490151 95053..97293 1 NC_002940.2 tail length tape measure protein 97293 1490151 HD0140 Haemophilus ducreyi 35000HP tail length tape measure protein NP_872746.1 95053 D 233412 CDS NP_872747.1 33151394 1490152 97275..97457 1 NC_002940.2 hypothetical protein 97457 1490152 HD0141 Haemophilus ducreyi 35000HP hypothetical protein NP_872747.1 97275 D 233412 CDS NP_872748.1 33151395 1490153 97508..97816 1 NC_002940.2 hypothetical protein 97816 1490153 HD0142 Haemophilus ducreyi 35000HP hypothetical protein NP_872748.1 97508 D 233412 CDS NP_872749.1 33151396 1490154 97831..98232 1 NC_002940.2 bacteriophage TM4 gp14 protein 98232 1490154 HD0143 Haemophilus ducreyi 35000HP bacteriophage TM4 gp14 protein NP_872749.1 97831 D 233412 CDS NP_872750.1 33151397 1490155 98214..98309 1 NC_002940.2 hypothetical protein 98309 1490155 HD0144 Haemophilus ducreyi 35000HP hypothetical protein NP_872750.1 98214 D 233412 CDS NP_872751.1 33151398 1490156 98318..99310 1 NC_002940.2 hypothetical protein 99310 1490156 HD0145 Haemophilus ducreyi 35000HP hypothetical protein NP_872751.1 98318 D 233412 CDS NP_872752.1 33151399 1490157 99312..100277 1 NC_002940.2 hypothetical protein 100277 1490157 HD0146 Haemophilus ducreyi 35000HP hypothetical protein NP_872752.1 99312 D 233412 CDS NP_872753.1 33151400 1490158 100283..100579 1 NC_002940.2 hypothetical protein 100579 1490158 HD0147 Haemophilus ducreyi 35000HP hypothetical protein NP_872753.1 100283 D 233412 CDS NP_872754.1 33151401 1490159 100604..101974 1 NC_002940.2 hypothetical protein 101974 1490159 HD0148 Haemophilus ducreyi 35000HP hypothetical protein NP_872754.1 100604 D 233412 CDS NP_872755.1 33151402 1490160 102012..102200 1 NC_002940.2 hypothetical protein 102200 1490160 HD0149 Haemophilus ducreyi 35000HP hypothetical protein NP_872755.1 102012 D 233412 CDS NP_872756.1 33151403 1490161 102209..102820 1 NC_002940.2 hypothetical protein 102820 1490161 HD0150 Haemophilus ducreyi 35000HP hypothetical protein NP_872756.1 102209 D 233412 CDS NP_872757.1 33151404 1490162 102830..103078 1 NC_002940.2 hypothetical protein 103078 1490162 HD0151 Haemophilus ducreyi 35000HP hypothetical protein NP_872757.1 102830 D 233412 CDS NP_872758.1 33151405 1490163 103082..103288 1 NC_002940.2 hypothetical protein 103288 1490163 HD0152 Haemophilus ducreyi 35000HP hypothetical protein NP_872758.1 103082 D 233412 CDS NP_872759.1 33151406 1490164 103288..103758 1 NC_002940.2 hypothetical protein 103758 1490164 HD0153 Haemophilus ducreyi 35000HP hypothetical protein NP_872759.1 103288 D 233412 CDS NP_872760.1 33151407 1490165 103742..105391 1 NC_002940.2 hypothetical protein 105391 1490165 HD0154 Haemophilus ducreyi 35000HP hypothetical protein NP_872760.1 103742 D 233412 CDS NP_872761.1 33151408 1490166 105420..106013 1 NC_002940.2 hypothetical protein 106013 1490166 HD0155 Haemophilus ducreyi 35000HP hypothetical protein NP_872761.1 105420 D 233412 CDS NP_872762.1 33151409 1490167 106110..106940 1 NC_002940.2 hypothetical protein 106940 1490167 HD0156 Haemophilus ducreyi 35000HP hypothetical protein NP_872762.1 106110 D 233412 CDS NP_872763.1 33151410 1490168 107120..107344 1 NC_002940.2 hypothetical protein 107344 1490168 HD0157 Haemophilus ducreyi 35000HP hypothetical protein NP_872763.1 107120 D 233412 CDS NP_872764.1 33151411 1490169 complement(107273..107386) 1 NC_002940.2 hypothetical protein 107386 1490169 HD0158 Haemophilus ducreyi 35000HP hypothetical protein NP_872764.1 107273 R 233412 CDS NP_872765.1 33151412 1490170 107754..108614 1 NC_002940.2 hypothetical protein 108614 1490170 HD0159 Haemophilus ducreyi 35000HP hypothetical protein NP_872765.1 107754 D 233412 CDS NP_872766.1 33151413 1490171 complement(108685..108795) 1 NC_002940.2 hypothetical protein 108795 1490171 HD0160 Haemophilus ducreyi 35000HP hypothetical protein NP_872766.1 108685 R 233412 CDS NP_872767.1 33151414 1490172 108921..109334 1 NC_002940.2 hypothetical protein 109334 1490172 HD0161 Haemophilus ducreyi 35000HP hypothetical protein NP_872767.1 108921 D 233412 CDS NP_872768.1 33151415 1490173 109890..109988 1 NC_002940.2 hypothetical protein 109988 1490173 HD0162 Haemophilus ducreyi 35000HP hypothetical protein NP_872768.1 109890 D 233412 CDS NP_872769.1 33151416 1490175 111069..112538 1 NC_002940.2 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 112538 mqo 1490175 mqo Haemophilus ducreyi 35000HP malate:quinone oxidoreductase NP_872769.1 111069 D 233412 CDS NP_872770.1 33151417 1490176 112673..113170 1 NC_002940.2 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 113170 menG 1490176 menG Haemophilus ducreyi 35000HP ribonuclease activity regulator protein RraA NP_872770.1 112673 D 233412 CDS NP_872771.1 33151418 1490177 complement(113225..113329) 1 NC_002940.2 hypothetical protein 113329 1490177 HD0167 Haemophilus ducreyi 35000HP hypothetical protein NP_872771.1 113225 R 233412 CDS NP_872772.1 33151419 1490178 complement(113672..113935) 1 NC_002940.2 hypothetical protein 113935 1490178 HD0168 Haemophilus ducreyi 35000HP hypothetical protein NP_872772.1 113672 R 233412 CDS NP_872773.1 33151420 1490179 114009..114536 1 NC_002940.2 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 114536 ppa 1490179 ppa Haemophilus ducreyi 35000HP inorganic pyrophosphatase NP_872773.1 114009 D 233412 CDS NP_872774.1 33151421 1490180 complement(114746..114904) 1 NC_002940.2 hypothetical protein 114904 1490180 HD0170 Haemophilus ducreyi 35000HP hypothetical protein NP_872774.1 114746 R 233412 CDS NP_872775.1 33151422 1490181 114974..115081 1 NC_002940.2 hypothetical protein 115081 1490181 HD0171 Haemophilus ducreyi 35000HP hypothetical protein NP_872775.1 114974 D 233412 CDS NP_872776.1 33151423 1490182 115108..115701 1 NC_002940.2 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 115701 nudH 1490182 nudH Haemophilus ducreyi 35000HP dinucleoside polyphosphate hydrolase NP_872776.1 115108 D 233412 CDS NP_872777.1 33151424 1490183 115704..116495 1 NC_002940.2 hypothetical protein 116495 1490183 HD0173 Haemophilus ducreyi 35000HP hypothetical protein NP_872777.1 115704 D 233412 CDS NP_872778.1 33151425 1490184 116565..117362 1 NC_002940.2 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 117362 lgt 1490184 lgt Haemophilus ducreyi 35000HP prolipoprotein diacylglyceryl transferase NP_872778.1 116565 D 233412 CDS NP_872779.1 33151426 1490185 complement(117345..117476) 1 NC_002940.2 hypothetical protein 117476 1490185 HD0175 Haemophilus ducreyi 35000HP hypothetical protein NP_872779.1 117345 R 233412 CDS NP_872780.1 33151427 1490186 117436..118098 1 NC_002940.2 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 118098 gph 1490186 gph Haemophilus ducreyi 35000HP phosphoglycolate phosphatase NP_872780.1 117436 D 233412 CDS NP_872781.1 33151428 1490187 118266..119294 1 NC_002940.2 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 119294 trpS 1490187 trpS Haemophilus ducreyi 35000HP tryptophanyl-tRNA synthetase NP_872781.1 118266 D 233412 CDS NP_872782.1 33151429 1490188 complement(119385..119831) 1 NC_002940.2 hypothetical protein 119831 1490188 HD0178 Haemophilus ducreyi 35000HP hypothetical protein NP_872782.1 119385 R 233412 CDS NP_872783.1 33151430 1490189 119914..121551 1 NC_002940.2 lon protease 121551 lonH 1490189 lonH Haemophilus ducreyi 35000HP lon protease NP_872783.1 119914 D 233412 CDS NP_872784.1 33151431 1490190 121573..121665 1 NC_002940.2 hypothetical protein 121665 1490190 HD0180 Haemophilus ducreyi 35000HP hypothetical protein NP_872784.1 121573 D 233412 CDS NP_872785.1 33151432 1490191 121662..122192 1 NC_002940.2 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 122192 fabA 1490191 fabA Haemophilus ducreyi 35000HP 3-hydroxydecanoyl-ACP dehydratase NP_872785.1 121662 D 233412 CDS NP_872786.1 33151433 1490192 122281..122820 1 NC_002940.2 hypothetical protein 122820 1490192 HD0182 Haemophilus ducreyi 35000HP hypothetical protein NP_872786.1 122281 D 233412 CDS NP_872787.1 33151434 1490193 122768..123487 1 NC_002940.2 hypothetical protein 123487 1490193 HD0183 Haemophilus ducreyi 35000HP hypothetical protein NP_872787.1 122768 D 233412 CDS NP_872788.1 33151435 1490194 123462..124148 1 NC_002940.2 hypothetical protein 124148 1490194 HD0184 Haemophilus ducreyi 35000HP hypothetical protein NP_872788.1 123462 D 233412 CDS NP_872789.1 33151436 1490195 124168..124458 1 NC_002940.2 hypothetical protein 124458 1490195 HD0185 Haemophilus ducreyi 35000HP hypothetical protein NP_872789.1 124168 D 233412 CDS NP_872790.1 33151437 1490196 124536..127877 1 NC_002940.2 exodeoxyribonuclease V subunit gamma 127877 recC 1490196 recC Haemophilus ducreyi 35000HP exodeoxyribonuclease V subunit gamma NP_872790.1 124536 D 233412 CDS NP_872791.1 33151438 1490197 127874..130828 1 NC_002940.2 protease III 130828 ptrA 1490197 ptrA Haemophilus ducreyi 35000HP protease III NP_872791.1 127874 D 233412 CDS NP_872792.1 33151439 1490198 complement(130926..132059) 1 NC_002940.2 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 132059 dnaJ 1490198 dnaJ Haemophilus ducreyi 35000HP molecular chaperone DnaJ NP_872792.1 130926 R 233412 CDS NP_872793.1 33151440 1490199 complement(132286..134190) 1 NC_002940.2 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 134190 dnaK 1490199 dnaK Haemophilus ducreyi 35000HP molecular chaperone DnaK NP_872793.1 132286 R 233412 CDS NP_872794.1 33151441 1490200 134398..136569 1 NC_002940.2 metallopeptidase 136569 pepO 1490200 pepO Haemophilus ducreyi 35000HP metallopeptidase NP_872794.1 134398 D 233412 CDS NP_872795.1 33151442 1490201 complement(134432..134533) 1 NC_002940.2 hypothetical protein 134533 1490201 HD0190 Haemophilus ducreyi 35000HP hypothetical protein NP_872795.1 134432 R 233412 CDS NP_872796.1 33151443 1490202 complement(136704..137174) 1 NC_002940.2 hypothetical protein 137174 1490202 HD0192 Haemophilus ducreyi 35000HP hypothetical protein NP_872796.1 136704 R 233412 CDS NP_872797.1 33151444 1490203 137257..137352 1 NC_002940.2 hypothetical protein 137352 1490203 HD0193 Haemophilus ducreyi 35000HP hypothetical protein NP_872797.1 137257 D 233412 CDS NP_872798.1 33151445 1490204 complement(137451..140393) 1 NC_002940.2 ribonuclease E 140393 rne 1490204 rne Haemophilus ducreyi 35000HP ribonuclease E NP_872798.1 137451 R 233412 CDS NP_872799.1 33151446 1490205 140859..141857 1 NC_002940.2 hypothetical protein 141857 1490205 HD0195 Haemophilus ducreyi 35000HP hypothetical protein NP_872799.1 140859 D 233412 CDS NP_872800.1 33151447 1490206 complement(141889..142410) 1 NC_002940.2 hypothetical protein 142410 1490206 HD0196 Haemophilus ducreyi 35000HP hypothetical protein NP_872800.1 141889 R 233412 CDS NP_872801.1 33151448 1490207 complement(142571..144034) 1 NC_002940.2 polyprenyl P-hydroxybenzoate decarboxylase; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 144034 ubiD 1490207 ubiD Haemophilus ducreyi 35000HP 3-octaprenyl-4-hydroxybenzoate carboxy-lyase NP_872801.1 142571 R 233412 CDS NP_872802.1 33151449 1490208 144181..145113 1 NC_002940.2 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 145113 znuA 1490208 znuA Haemophilus ducreyi 35000HP high-affinity zinc transporter periplasmic protein NP_872802.1 144181 D 233412 CDS NP_872803.1 33151450 1490209 complement(145225..145884) 1 NC_002940.2 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 145884 rpiA 1490209 rpiA Haemophilus ducreyi 35000HP ribose-5-phosphate isomerase A NP_872803.1 145225 R 233412 CDS NP_872804.1 33151451 1490210 complement(145999..147333) 1 NC_002940.2 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 147333 glmM 1490210 glmM Haemophilus ducreyi 35000HP phosphoglucosamine mutase NP_872804.1 145999 R 233412 CDS NP_872805.1 33151452 1490211 complement(147529..148098) 1 NC_002940.2 FKBP-type peptidylprolyl isomerase 148098 slyD 1490211 slyD Haemophilus ducreyi 35000HP FKBP-type peptidylprolyl isomerase NP_872805.1 147529 R 233412 CDS NP_872806.1 33151453 1490212 148390..148701 1 NC_002940.2 50S ribosomal protein L21 148701 rplU 1490212 rplU Haemophilus ducreyi 35000HP 50S ribosomal protein L21 NP_872806.1 148390 D 233412 CDS NP_872807.1 33151454 1490213 148722..148979 1 NC_002940.2 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 148979 rpmA 1490213 rpmA Haemophilus ducreyi 35000HP 50S ribosomal protein L27 NP_872807.1 148722 D 233412 CDS NP_872808.1 33151455 1490214 149085..150017 1 NC_002940.2 hypothetical protein 150017 1490214 HD0206 Haemophilus ducreyi 35000HP hypothetical protein NP_872808.1 149085 D 233412 CDS NP_872809.1 33151456 1490215 complement(150068..150877) 1 NC_002940.2 hypothetical protein 150877 1490215 HD0207 Haemophilus ducreyi 35000HP hypothetical protein NP_872809.1 150068 R 233412 CDS NP_872810.1 33151457 1490216 150998..151675 1 NC_002940.2 competence protein F 151675 comF 1490216 comF Haemophilus ducreyi 35000HP competence protein F NP_872810.1 150998 D 233412 CDS NP_872811.1 33151458 1490217 complement(151724..152713) 1 NC_002940.2 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 152713 rsmC 1490217 rsmC Haemophilus ducreyi 35000HP 16S ribosomal RNA m2G1207 methyltransferase NP_872811.1 151724 R 233412 CDS NP_872812.1 33151459 1490218 152892..153296 1 NC_002940.2 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 153296 holD 1490218 holD Haemophilus ducreyi 35000HP DNA polymerase III subunit psi NP_872812.1 152892 D 233412 CDS NP_872813.1 33151460 1490219 153305..153742 1 NC_002940.2 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 153742 rimI 1490219 rimI Haemophilus ducreyi 35000HP ribosomal-protein-alanine N-acetyltransferase NP_872813.1 153305 D 233412 CDS NP_872814.1 33151461 1490220 153787..155115 1 NC_002940.2 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 155115 srmB 1490220 srmB Haemophilus ducreyi 35000HP ATP-dependent RNA helicase SrmB NP_872814.1 153787 D 233412 CDS NP_872815.1 33151462 1490221 155182..155811 1 NC_002940.2 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 155811 pdxH 1490221 pdxH Haemophilus ducreyi 35000HP pyridoxamine 5'-phosphate oxidase NP_872815.1 155182 D 233412 CDS NP_872816.1 33151463 1490222 complement(155855..157489) 1 NC_002940.2 heme-binding protein A 157489 hbpA 1490222 hbpA Haemophilus ducreyi 35000HP heme-binding protein A NP_872816.1 155855 R 233412 CDS NP_872817.1 33151464 1490223 complement(157650..157817) 1 NC_002940.2 hypothetical protein 157817 1490223 HD0216 Haemophilus ducreyi 35000HP hypothetical protein NP_872817.1 157650 R 233412 CDS NP_872818.1 33151465 1490224 complement(157810..158796) 1 NC_002940.2 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 158796 lpxK 1490224 lpxK Haemophilus ducreyi 35000HP tetraacyldisaccharide 4'-kinase NP_872818.1 157810 R 233412 CDS NP_872819.1 33151466 1490225 complement(158826..160082) 1 NC_002940.2 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding protein ClpX 160082 clpX 1490225 clpX Haemophilus ducreyi 35000HP ATP-dependent protease ATP-binding protein ClpX NP_872819.1 158826 R 233412 CDS NP_872820.1 33151467 1490226 complement(160082..160675) 1 NC_002940.2 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 160675 clpP 1490226 clpP Haemophilus ducreyi 35000HP ATP-dependent Clp protease proteolytic subunit NP_872820.1 160082 R 233412 CDS NP_872821.1 33151468 1490227 160813..161205 1 NC_002940.2 hypothetical protein 161205 1490227 HD0222 Haemophilus ducreyi 35000HP hypothetical protein NP_872821.1 160813 D 233412 CDS NP_872822.1 33151469 1490229 complement(161456..162226) 1 NC_002940.2 DNA polymerase III subunit epsilon 162226 dnaQ 1490229 dnaQ Haemophilus ducreyi 35000HP DNA polymerase III subunit epsilon NP_872822.1 161456 R 233412 CDS NP_872823.1 33151470 1490230 complement(162299..163969) 1 NC_002940.2 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 163969 1490230 HD0224 Haemophilus ducreyi 35000HP ABC transporter ATP-binding protein NP_872823.1 162299 R 233412 CDS NP_872824.1 33151471 1490231 complement(164055..165482) 1 NC_002940.2 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 165482 1490231 HD0226 Haemophilus ducreyi 35000HP (dimethylallyl)adenosine tRNA methylthiotransferase NP_872824.1 164055 R 233412 CDS NP_872825.1 33151472 1490232 complement(165662..166165) 1 NC_002940.2 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 166165 crr 1490232 crr Haemophilus ducreyi 35000HP PTS system glucose-specific transporter NP_872825.1 165662 R 233412 CDS NP_872826.1 33151473 1490233 complement(166255..167976) 1 NC_002940.2 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 167976 ptsI 1490233 ptsI Haemophilus ducreyi 35000HP phosphoenolpyruvate-protein phosphotransferase NP_872826.1 166255 R 233412 CDS NP_872827.1 33151474 1490234 complement(168107..168364) 1 NC_002940.2 PTS system phosphocarrier protein HPr 168364 ptsH 1490234 ptsH Haemophilus ducreyi 35000HP PTS system phosphocarrier protein HPr NP_872827.1 168107 R 233412 CDS NP_872828.1 33151475 1490235 168639..170225 1 NC_002940.2 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 170225 thiP 1490235 thiP Haemophilus ducreyi 35000HP thiamine transporter membrane protein NP_872828.1 168639 D 233412 CDS NP_872829.1 33151476 1490236 170222..170863 1 NC_002940.2 thiamin ABC transporter ATP-binding protein 170863 thiQ 1490236 thiQ Haemophilus ducreyi 35000HP thiamin ABC transporter ATP-binding protein NP_872829.1 170222 D 233412 CDS NP_872830.1 33151477 1490237 complement(170989..171993) 1 NC_002940.2 ornithine carbamoyltransferase 171993 arcB1 1490237 arcB1 Haemophilus ducreyi 35000HP ornithine carbamoyltransferase NP_872830.1 170989 R 233412 CDS NP_872831.1 33151478 1490238 complement(172092..175319) 1 NC_002940.2 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 175319 carB 1490238 carB Haemophilus ducreyi 35000HP carbamoyl phosphate synthase large subunit NP_872831.1 172092 R 233412 CDS NP_872832.1 33151479 1490239 complement(175357..176526) 1 NC_002940.2 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 176526 carA 1490239 carA Haemophilus ducreyi 35000HP carbamoyl phosphate synthase small subunit NP_872832.1 175357 R 233412 CDS NP_872833.1 33151480 1490240 complement(176633..176782) 1 NC_002940.2 hypothetical protein 176782 1490240 HD0236 Haemophilus ducreyi 35000HP hypothetical protein NP_872833.1 176633 R 233412 CDS NP_872834.1 33151481 1490241 176846..178180 1 NC_002940.2 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 178180 dcuB2 1490241 dcuB2 Haemophilus ducreyi 35000HP anaerobic C4-dicarboxylate transporter NP_872834.1 176846 D 233412 CDS NP_872835.1 33151482 1490242 178184..178312 1 NC_002940.2 hypothetical protein 178312 1490242 HD0238 Haemophilus ducreyi 35000HP hypothetical protein NP_872835.1 178184 D 233412 CDS NP_872836.1 33151483 1490243 178471..179412 1 NC_002940.2 S-adenosyl-methyltransferase MraW 179412 mraW 1490243 mraW Haemophilus ducreyi 35000HP S-adenosyl-methyltransferase MraW NP_872836.1 178471 D 233412 CDS NP_872837.1 33151484 1490244 179425..179739 1 NC_002940.2 cell division protein FtsL 179739 ftsL 1490244 ftsL Haemophilus ducreyi 35000HP cell division protein FtsL NP_872837.1 179425 D 233412 CDS NP_872838.1 33151485 1490245 179745..181790 1 NC_002940.2 penicillin-binding protein 3 181790 ftsI 1490245 ftsI Haemophilus ducreyi 35000HP penicillin-binding protein 3 NP_872838.1 179745 D 233412 CDS NP_872839.1 33151486 1490246 181813..183318 1 NC_002940.2 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 183318 murE 1490246 murE Haemophilus ducreyi 35000HP UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase NP_872839.1 181813 D 233412 CDS NP_872840.1 33151487 1490247 183362..184765 1 NC_002940.2 UDP-MurNAc-pentapeptide synthetase 184765 murF 1490247 murF Haemophilus ducreyi 35000HP UDP-MurNAc-pentapeptide synthetase NP_872840.1 183362 D 233412 CDS NP_872841.1 33151488 1490248 184765..185847 1 NC_002940.2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 185847 mraY 1490248 mraY Haemophilus ducreyi 35000HP phospho-N-acetylmuramoyl-pentapeptide- transferase NP_872841.1 184765 D 233412 CDS NP_872842.1 33151489 1490249 185927..187234 1 NC_002940.2 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 187234 murD 1490249 murD Haemophilus ducreyi 35000HP UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase NP_872842.1 185927 D 233412 CDS NP_872843.1 33151490 1490250 187238..188431 1 NC_002940.2 cell division protein FtsW 188431 ftsW 1490250 ftsW Haemophilus ducreyi 35000HP cell division protein FtsW NP_872843.1 187238 D 233412 CDS NP_872844.1 33151491 1490251 188468..188959 1 NC_002940.2 hypothetical protein 188959 1490251 HD0247 Haemophilus ducreyi 35000HP hypothetical protein NP_872844.1 188468 D 233412 CDS NP_872845.1 33151492 1490252 complement(189019..189825) 1 NC_002940.2 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 189825 map 1490252 map Haemophilus ducreyi 35000HP methionine aminopeptidase NP_872845.1 189019 R 233412 CDS NP_872846.1 33151493 1490253 complement(189914..190579) 1 NC_002940.2 hypothetical protein 190579 1490253 HD0250 Haemophilus ducreyi 35000HP hypothetical protein NP_872846.1 189914 R 233412 CDS NP_872847.1 33151494 1490255 complement(191658..192938) 1 NC_002940.2 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 192938 murA 1490255 murA Haemophilus ducreyi 35000HP UDP-N-acetylglucosamine 1-carboxyvinyltransferase NP_872847.1 191658 R 233412 CDS NP_872848.1 33151495 1490256 complement(193041..193301) 1 NC_002940.2 hypothetical protein 193301 1490256 HD0254 Haemophilus ducreyi 35000HP hypothetical protein NP_872848.1 193041 R 233412 CDS NP_872849.1 33151496 1490257 complement(193310..193651) 1 NC_002940.2 anti-sigma factor B antagonist 193651 1490257 HD0255 Haemophilus ducreyi 35000HP anti-sigma factor B antagonist NP_872849.1 193310 R 233412 CDS NP_872850.1 33151497 1490258 complement(193659..194297) 1 NC_002940.2 hypothetical protein 194297 1490258 HD0256 Haemophilus ducreyi 35000HP hypothetical protein NP_872850.1 193659 R 233412 CDS NP_872851.1 33151498 1490259 complement(194398..194883) 1 NC_002940.2 hypothetical protein 194883 1490259 HD0257 Haemophilus ducreyi 35000HP hypothetical protein NP_872851.1 194398 R 233412 CDS NP_872852.1 33151499 1490260 complement(194904..195683) 1 NC_002940.2 permease 195683 1490260 HD0258 Haemophilus ducreyi 35000HP permease NP_872852.1 194904 R 233412 CDS NP_872853.1 33151500 1490261 complement(195673..196476) 1 NC_002940.2 ABC transporter ATP-binding protein 196476 1490261 HD0259 Haemophilus ducreyi 35000HP ABC transporter ATP-binding protein NP_872853.1 195673 R 233412 CDS NP_872854.1 33151501 1490262 196739..198157 1 NC_002940.2 periplasmic serine protease do 198157 degP 1490262 degP Haemophilus ducreyi 35000HP periplasmic serine protease do NP_872854.1 196739 D 233412 CDS NP_872855.1 33151502 1490263 complement(198202..199095) 1 NC_002940.2 hypothetical protein 199095 1490263 HD0261 Haemophilus ducreyi 35000HP hypothetical protein NP_872855.1 198202 R 233412 CDS NP_872856.1 33151503 1490264 complement(199095..199556) 1 NC_002940.2 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 199556 argR 1490264 argR Haemophilus ducreyi 35000HP arginine repressor ArgR NP_872856.1 199095 R 233412 CDS NP_872857.1 33151504 1490265 199746..200720 1 NC_002940.2 oxidizes malate to oxaloacetate; malate dehydrogenase 200720 mdh 1490265 mdh Haemophilus ducreyi 35000HP malate dehydrogenase NP_872857.1 199746 D 233412 CDS NP_872858.1 33151505 1490266 complement(200788..201258) 1 NC_002940.2 hypothetical protein 201258 lpp 1490266 lpp Haemophilus ducreyi 35000HP hypothetical protein NP_872858.1 200788 R 233412 CDS NP_872859.1 33151506 1490267 complement(201282..201878) 1 NC_002940.2 hypothetical protein 201878 1490267 HD0267 Haemophilus ducreyi 35000HP hypothetical protein NP_872859.1 201282 R 233412 CDS NP_872860.2 161511522 1490268 201978..203705 1 NC_002940.2 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 203705 argS 1490268 argS Haemophilus ducreyi 35000HP arginyl-tRNA synthetase NP_872860.2 201978 D 233412 CDS NP_872861.1 33151508 1490269 203812..204987 1 NC_002940.2 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 204987 obgE 1490269 obgE Haemophilus ducreyi 35000HP GTPase ObgE NP_872861.1 203812 D 233412 CDS NP_872862.1 33151509 1490270 complement(205071..205811) 1 NC_002940.2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 205811 1490270 HD0270 Haemophilus ducreyi 35000HP 23S rRNA (guanosine-2'-O-)-methyltransferase NP_872862.1 205071 R 233412 CDS NP_872863.1 33151510 1490271 complement(205844..207208) 1 NC_002940.2 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 207208 pssA 1490271 pssA Haemophilus ducreyi 35000HP phosphatidylserine synthase NP_872863.1 205844 R 233412 CDS NP_872864.1 33151511 1490272 complement(207310..210117) 1 NC_002940.2 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 210117 ileS 1490272 ileS Haemophilus ducreyi 35000HP isoleucyl-tRNA synthetase NP_872864.1 207310 R 233412 CDS NP_872865.1 33151512 1490273 complement(210152..211132) 1 NC_002940.2 riboflavin biosynthesis protein RibF 211132 ribF 1490273 ribF Haemophilus ducreyi 35000HP riboflavin biosynthesis protein RibF NP_872865.1 210152 R 233412 CDS NP_872866.1 33151513 1490275 212735..212932 1 NC_002940.2 hypothetical protein 212932 1490275 HD0276 Haemophilus ducreyi 35000HP hypothetical protein NP_872866.1 212735 D 233412 CDS NP_872867.1 33151514 1490276 212929..213438 1 NC_002940.2 phosphoesterase 213438 1490276 HD0277 Haemophilus ducreyi 35000HP phosphoesterase NP_872867.1 212929 D 233412 CDS NP_872868.1 33151515 1490277 213635..214348 1 NC_002940.2 two-component response regulator 214348 arcA 1490277 arcA Haemophilus ducreyi 35000HP two-component response regulator NP_872868.1 213635 D 233412 CDS NP_872869.1 33151516 1490278 214484..215005 1 NC_002940.2 hypothetical protein 215005 1490278 HD0279 Haemophilus ducreyi 35000HP hypothetical protein NP_872869.1 214484 D 233412 CDS NP_872870.1 33151517 1490279 complement(215430..215663) 1 NC_002940.2 hypothetical protein 215663 1490279 HD0280 Haemophilus ducreyi 35000HP hypothetical protein NP_872870.1 215430 R 233412 CDS NP_872871.1 33151518 1490280 215687..216253 1 NC_002940.2 fimbrial major pilin protein 216253 fimA 1490280 fimA Haemophilus ducreyi 35000HP fimbrial major pilin protein NP_872871.1 215687 D 233412 CDS NP_872872.1 33151519 1490281 216292..216789 1 NC_002940.2 fimbrial structural subunit 216789 fimB 1490281 fimB Haemophilus ducreyi 35000HP fimbrial structural subunit NP_872872.1 216292 D 233412 CDS NP_872873.1 33151520 1490282 216833..219334 1 NC_002940.2 fimbrial outer membrane usher protein 219334 fimC 1490282 fimC Haemophilus ducreyi 35000HP fimbrial outer membrane usher protein NP_872873.1 216833 D 233412 CDS NP_872874.1 33151521 1490283 219386..220126 1 NC_002940.2 periplasmic fimbrial chaperone 220126 fimD 1490283 fimD Haemophilus ducreyi 35000HP periplasmic fimbrial chaperone NP_872874.1 219386 D 233412 CDS NP_872875.1 33151522 1490284 220188..220709 1 NC_002940.2 minor fimbrial subunit 220709 1490284 HD0285 Haemophilus ducreyi 35000HP minor fimbrial subunit NP_872875.1 220188 D 233412 CDS NP_872876.1 33151523 1490285 220769..221290 1 NC_002940.2 hypothetical protein 221290 1490285 HD0286 Haemophilus ducreyi 35000HP hypothetical protein NP_872876.1 220769 D 233412 CDS NP_872877.1 33151524 1490286 221365..221835 1 NC_002940.2 hypothetical protein 221835 1490286 HD0287 Haemophilus ducreyi 35000HP hypothetical protein NP_872877.1 221365 D 233412 CDS NP_872878.1 33151525 1490287 221870..222337 1 NC_002940.2 hypothetical protein 222337 1490287 HD0288 Haemophilus ducreyi 35000HP hypothetical protein NP_872878.1 221870 D 233412 CDS NP_872879.1 33151526 1490288 complement(222366..222851) 1 NC_002940.2 hypothetical protein 222851 1490288 HD0289 Haemophilus ducreyi 35000HP hypothetical protein NP_872879.1 222366 R 233412 CDS NP_872880.1 33151527 1490289 complement(222797..223390) 1 NC_002940.2 hypothetical protein 223390 1490289 HD0290 Haemophilus ducreyi 35000HP hypothetical protein NP_872880.1 222797 R 233412 CDS NP_872881.1 33151528 1490290 complement(223368..223835) 1 NC_002940.2 transposase 223835 1490290 HD0291 Haemophilus ducreyi 35000HP transposase NP_872881.1 223368 R 233412 CDS NP_872882.1 33151529 1490291 223958..224296 1 NC_002940.2 hypothetical protein 224296 1490291 HD0292 Haemophilus ducreyi 35000HP hypothetical protein NP_872882.1 223958 D 233412 CDS NP_872883.1 33151530 1490292 224483..225823 1 NC_002940.2 type II DNA modification (methyltransferase 225823 1490292 HD0293 Haemophilus ducreyi 35000HP type II DNA modification (methyltransferase NP_872883.1 224483 D 233412 CDS NP_872884.1 33151531 1490293 225932..226924 1 NC_002940.2 type II DNA restriction endonuclease 226924 1490293 HD0294 Haemophilus ducreyi 35000HP type II DNA restriction endonuclease NP_872884.1 225932 D 233412 CDS NP_872885.1 33151532 1490294 227282..227635 1 NC_002940.2 hypothetical protein 227635 1490294 HD0295 Haemophilus ducreyi 35000HP hypothetical protein NP_872885.1 227282 D 233412 CDS NP_872886.1 33151533 1490295 227681..228172 1 NC_002940.2 hypothetical protein 228172 1490295 HD0296 Haemophilus ducreyi 35000HP hypothetical protein NP_872886.1 227681 D 233412 CDS NP_872887.1 33151534 1490296 complement(228350..228886) 1 NC_002940.2 hypothetical protein 228886 1490296 HD0297 Haemophilus ducreyi 35000HP hypothetical protein NP_872887.1 228350 R 233412 CDS NP_872888.1 33151535 1490297 228941..229645 1 NC_002940.2 K+ uptake protein 229645 fkuA 1490297 fkuA Haemophilus ducreyi 35000HP K+ uptake protein NP_872888.1 228941 D 233412 CDS NP_872889.1 33151536 1490298 229829..231676 1 NC_002940.2 GTP-binding protein, elongation factor typA/bipA-like protein 231676 typA 1490298 typA Haemophilus ducreyi 35000HP GTP-binding protein, elongation factor typA/bipA-like protein NP_872889.1 229829 D 233412 CDS NP_872890.1 33151537 1490299 231796..232059 1 NC_002940.2 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 232059 grxA 1490299 grxA Haemophilus ducreyi 35000HP glutaredoxin NP_872890.1 231796 D 233412 CDS NP_872891.1 33151538 1490300 complement(232099..232815) 1 NC_002940.2 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 232815 rph 1490300 rph Haemophilus ducreyi 35000HP ribonuclease PH NP_872891.1 232099 R 233412 CDS NP_872892.1 33151539 1490301 232966..233829 1 NC_002940.2 hypothetical protein 233829 1490301 HD0302 Haemophilus ducreyi 35000HP hypothetical protein NP_872892.1 232966 D 233412 CDS NP_872893.1 33151540 1490302 233837..234724 1 NC_002940.2 hypothetical protein 234724 1490302 HD0303 Haemophilus ducreyi 35000HP hypothetical protein NP_872893.1 233837 D 233412 CDS NP_872894.1 33151541 1490303 complement(234781..235041) 1 NC_002940.2 ferredoxin 235041 fdx1 1490303 fdx1 Haemophilus ducreyi 35000HP ferredoxin NP_872894.1 234781 R 233412 CDS NP_872895.1 33151542 1490304 complement(235104..235745) 1 NC_002940.2 nitrate/nitrite response regulator protein 235745 narP 1490304 narP Haemophilus ducreyi 35000HP nitrate/nitrite response regulator protein NP_872895.1 235104 R 233412 CDS NP_872896.1 33151543 1490305 complement(235841..235948) 1 NC_002940.2 hypothetical protein 235948 1490305 HD0306 Haemophilus ducreyi 35000HP hypothetical protein NP_872896.1 235841 R 233412 CDS NP_872897.1 33151544 1490306 235938..238085 1 NC_002940.2 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 238085 rlmL 1490306 rlmL Haemophilus ducreyi 35000HP 23S rRNA m(2)G2445 methyltransferase NP_872897.1 235938 D 233412 CDS NP_872898.1 33151545 1490307 238123..238602 1 NC_002940.2 tRNA/rRNA methyltransferase 238602 1490307 HD0308 Haemophilus ducreyi 35000HP tRNA/rRNA methyltransferase NP_872898.1 238123 D 233412 CDS NP_872899.1 33151546 1490308 complement(238701..239648) 1 NC_002940.2 Maintains the balance of metabolites in the pentose-phosphate pathway; transaldolase B 239648 tal 1490308 tal Haemophilus ducreyi 35000HP transaldolase B NP_872899.1 238701 R 233412 CDS NP_872900.1 33151547 1490315 246105..246221 1 NC_002940.2 hypothetical protein 246221 1490315 HD0311 Haemophilus ducreyi 35000HP hypothetical protein NP_872900.1 246105 D 233412 CDS NP_872901.1 33151548 1490316 246284..247288 1 NC_002940.2 dipeptide transport system permease 247288 dppB 1490316 dppB Haemophilus ducreyi 35000HP dipeptide transport system permease NP_872901.1 246284 D 233412 CDS NP_872902.1 33151549 1490317 247309..248196 1 NC_002940.2 dipeptide transport system permease 248196 dppC 1490317 dppC Haemophilus ducreyi 35000HP dipeptide transport system permease NP_872902.1 247309 D 233412 CDS NP_872903.1 33151550 1490318 248208..249212 1 NC_002940.2 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding protein 249212 dppD 1490318 dppD Haemophilus ducreyi 35000HP dipeptide transporter ATP-binding protein NP_872903.1 248208 D 233412 CDS NP_872904.1 33151551 1490319 249190..250194 1 NC_002940.2 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding protein 250194 dppF 1490319 dppF Haemophilus ducreyi 35000HP dipeptide transporter ATP-binding protein NP_872904.1 249190 D 233412 CDS NP_872905.1 33151552 1490320 complement(250251..252569) 1 NC_002940.2 transcription accessory protein tex-like protein 252569 1490320 HD0317 Haemophilus ducreyi 35000HP transcription accessory protein tex-like protein NP_872905.1 250251 R 233412 CDS NP_872906.1 33151553 1490321 complement(252640..253185) 1 NC_002940.2 fimbrial biogenesis and twitching motility protein PilF-like protein 253185 1490321 HD0318 Haemophilus ducreyi 35000HP fimbrial biogenesis and twitching motility protein PilF-like protein NP_872906.1 252640 R 233412 CDS NP_872907.1 33151554 1490322 complement(253224..254405) 1 NC_002940.2 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 254405 1490322 HD0319 Haemophilus ducreyi 35000HP ribosomal RNA large subunit methyltransferase N NP_872907.1 253224 R 233412 CDS NP_872908.1 33151555 1490325 255170..256609 1 NC_002940.2 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 256609 gltX 1490325 gltX Haemophilus ducreyi 35000HP glutamyl-tRNA synthetase NP_872908.1 255170 D 233412 CDS NP_872909.1 33151556 1490327 complement(256863..257504) 1 NC_002940.2 manganese superoxide dismutase 257504 sodA 1490327 sodA Haemophilus ducreyi 35000HP manganese superoxide dismutase NP_872909.1 256863 R 233412 CDS NP_872910.1 33151557 1490328 complement(257643..257996) 1 NC_002940.2 hypothetical protein 257996 1490328 HD0322 Haemophilus ducreyi 35000HP hypothetical protein NP_872910.1 257643 R 233412 CDS NP_872911.1 33151558 1490329 258033..258131 1 NC_002940.2 hypothetical protein 258131 1490329 HD0323 Haemophilus ducreyi 35000HP hypothetical protein NP_872911.1 258033 D 233412 CDS NP_872912.1 33151559 1490330 complement(258140..258463) 1 NC_002940.2 glutaredoxin-like protein 258463 1490330 HD0324 Haemophilus ducreyi 35000HP glutaredoxin-like protein NP_872912.1 258140 R 233412 CDS NP_872913.1 33151560 1490331 complement(258535..259140) 1 NC_002940.2 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 259140 recR 1490331 recR Haemophilus ducreyi 35000HP recombination protein RecR NP_872913.1 258535 R 233412 CDS NP_872914.1 33151561 1490332 complement(259206..259535) 1 NC_002940.2 hypothetical protein 259535 1490332 HD0326 Haemophilus ducreyi 35000HP hypothetical protein NP_872914.1 259206 R 233412 CDS NP_872915.1 33151562 1490333 complement(259687..260526) 1 NC_002940.2 TobB energy transducing protein 260526 tonB 1490333 tonB Haemophilus ducreyi 35000HP TobB energy transducing protein NP_872915.1 259687 R 233412 CDS NP_872916.1 33151563 1490334 complement(260536..260925) 1 NC_002940.2 biopolymer transport protein 260925 exbD 1490334 exbD Haemophilus ducreyi 35000HP biopolymer transport protein NP_872916.1 260536 R 233412 CDS NP_872917.1 33151564 1490335 complement(260970..261422) 1 NC_002940.2 biopolymer transport protein 261422 exbB 1490335 exbB Haemophilus ducreyi 35000HP biopolymer transport protein NP_872917.1 260970 R 233412 CDS NP_872918.1 33151565 1490336 261618..261950 1 NC_002940.2 thiosulfate sulfurtransferase 261950 glpE 1490336 glpE Haemophilus ducreyi 35000HP thiosulfate sulfurtransferase NP_872918.1 261618 D 233412 CDS NP_872919.1 33151566 1490337 261966..262811 1 NC_002940.2 thioredoxin-like protein 262811 1490337 HD0331 Haemophilus ducreyi 35000HP thioredoxin-like protein NP_872919.1 261966 D 233412 CDS NP_872920.1 33151567 1490338 262768..262872 1 NC_002940.2 hypothetical protein 262872 1490338 HD0332 Haemophilus ducreyi 35000HP hypothetical protein NP_872920.1 262768 D 233412 CDS NP_872921.1 33151568 1490339 262911..263864 1 NC_002940.2 thioredoxin reductase 263864 trxB 1490339 trxB Haemophilus ducreyi 35000HP thioredoxin reductase NP_872921.1 262911 D 233412 CDS NP_872922.1 33151569 1490340 263881..264642 1 NC_002940.2 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 264642 kdsB 1490340 kdsB Haemophilus ducreyi 35000HP 3-deoxy-manno-octulosonate cytidylyltransferase NP_872922.1 263881 D 233412 CDS NP_872923.1 33151570 1490341 complement(264625..264732) 1 NC_002940.2 hypothetical protein 264732 1490341 HD0336 Haemophilus ducreyi 35000HP hypothetical protein NP_872923.1 264625 R 233412 CDS NP_872924.1 33151571 1490342 complement(264722..265411) 1 NC_002940.2 pseudouridylate synthase 265411 rluB 1490342 rluB Haemophilus ducreyi 35000HP pseudouridylate synthase NP_872924.1 264722 R 233412 CDS NP_872925.1 33151572 1490343 complement(265415..265837) 1 NC_002940.2 hypothetical protein 265837 1490343 HD0338 Haemophilus ducreyi 35000HP hypothetical protein NP_872925.1 265415 R 233412 CDS NP_872926.1 33151573 1490344 266020..266259 1 NC_002940.2 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 266259 sirA 1490344 sirA Haemophilus ducreyi 35000HP sulfur transfer protein SirA NP_872926.1 266020 D 233412 CDS NP_872927.1 33151574 1490345 complement(266374..266805) 1 NC_002940.2 hypothetical protein 266805 1490345 HD0340 Haemophilus ducreyi 35000HP hypothetical protein NP_872927.1 266374 R 233412 CDS NP_872928.1 33151575 1490346 complement(266807..267439) 1 NC_002940.2 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 267439 engB 1490346 engB Haemophilus ducreyi 35000HP ribosome biogenesis GTP-binding protein YsxC NP_872928.1 266807 R 233412 CDS NP_872929.1 33151576 1490347 complement(267500..267922) 1 NC_002940.2 hypothetical protein 267922 1490347 HD0343 Haemophilus ducreyi 35000HP hypothetical protein NP_872929.1 267500 R 233412 CDS NP_872930.1 33151577 1490348 268342..269808 1 NC_002940.2 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 269808 nrfA 1490348 nrfA Haemophilus ducreyi 35000HP cytochrome c552 NP_872930.1 268342 D 233412 CDS NP_872931.1 33151578 1490349 269829..270473 1 NC_002940.2 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 270473 nrfB 1490349 nrfB Haemophilus ducreyi 35000HP cytochrome c nitrite reductase pentaheme subunit NP_872931.1 269829 D 233412 CDS NP_872932.1 33151579 1490350 270473..271150 1 NC_002940.2 nitrate reductase, Fe-S protein 271150 nrfC 1490350 nrfC Haemophilus ducreyi 35000HP nitrate reductase, Fe-S protein NP_872932.1 270473 D 233412 CDS NP_872933.1 33151580 1490351 271150..272115 1 NC_002940.2 nitrate reductase, transmembrane protein 272115 nrfD 1490351 nrfD Haemophilus ducreyi 35000HP nitrate reductase, transmembrane protein NP_872933.1 271150 D 233412 CDS NP_872934.1 33151581 1490352 272333..273913 1 NC_002940.2 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 273913 prfC 1490352 prfC Haemophilus ducreyi 35000HP peptide chain release factor 3 NP_872934.1 272333 D 233412 CDS NP_872935.1 33151582 1490353 274007..274099 1 NC_002940.2 hypothetical protein 274099 1490353 HD0352 Haemophilus ducreyi 35000HP hypothetical protein NP_872935.1 274007 D 233412 CDS NP_872936.1 33151583 1490354 274131..275000 1 NC_002940.2 metalloprotease; heat shock protein HtpX 275000 htpX 1490354 htpX Haemophilus ducreyi 35000HP heat shock protein HtpX NP_872936.1 274131 D 233412 CDS NP_872937.1 33151584 1490355 275169..276539 1 NC_002940.2 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 276539 gshR 1490355 gshR Haemophilus ducreyi 35000HP glutathione reductase NP_872937.1 275169 D 233412 CDS NP_872938.1 33151585 1490356 complement(276603..277403) 1 NC_002940.2 deoxyribonuclease 277403 1490356 HD0356 Haemophilus ducreyi 35000HP deoxyribonuclease NP_872938.1 276603 R 233412 CDS NP_872939.1 33151586 1490357 complement(277467..279053) 1 NC_002940.2 carbon starvation protein A 279053 1490357 HD0357 Haemophilus ducreyi 35000HP carbon starvation protein A NP_872939.1 277467 R 233412 CDS NP_872940.1 33151587 1490358 complement(279428..279919) 1 NC_002940.2 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 279919 1490358 HD0358 Haemophilus ducreyi 35000HP nucleotide-binding protein NP_872940.1 279428 R 233412 CDS NP_872941.1 33151588 1490359 complement(279932..280072) 1 NC_002940.2 hypothetical protein 280072 1490359 HD0359 Haemophilus ducreyi 35000HP hypothetical protein NP_872941.1 279932 R 233412 CDS NP_872942.1 33151589 1490360 280189..280851 1 NC_002940.2 AphA (smp-like) protein 280851 aphA 1490360 aphA Haemophilus ducreyi 35000HP AphA (smp-like) protein NP_872942.1 280189 D 233412 CDS NP_872943.1 33151590 1490361 280938..281156 1 NC_002940.2 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 281156 infA 1490361 infA Haemophilus ducreyi 35000HP translation initiation factor IF-1 NP_872943.1 280938 D 233412 CDS NP_872944.1 33151591 1490362 complement(281227..282417) 1 NC_002940.2 hypothetical protein 282417 1490362 HD0362 Haemophilus ducreyi 35000HP hypothetical protein NP_872944.1 281227 R 233412 CDS NP_872945.1 33151592 1490363 complement(282448..283434) 1 NC_002940.2 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 283434 1490363 HD0363 Haemophilus ducreyi 35000HP aspartate-semialdehyde dehydrogenase NP_872945.1 282448 R 233412 CDS NP_872946.1 33151593 1490364 283516..283989 1 NC_002940.2 transcriptional regulator 283989 1490364 HD0364 Haemophilus ducreyi 35000HP transcriptional regulator NP_872946.1 283516 D 233412 CDS NP_872947.1 33151594 1490365 284215..284511 1 NC_002940.2 LexA regulated protein 284511 1490365 HD0365 Haemophilus ducreyi 35000HP LexA regulated protein NP_872947.1 284215 D 233412 CDS NP_872948.1 33151595 1490366 284522..285046 1 NC_002940.2 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 285046 fldA 1490366 fldA Haemophilus ducreyi 35000HP flavodoxin FldA NP_872948.1 284522 D 233412 CDS NP_872949.1 33151596 1490367 285076..285525 1 NC_002940.2 ferric uptake regulation protein 285525 fur 1490367 fur Haemophilus ducreyi 35000HP ferric uptake regulation protein NP_872949.1 285076 D 233412 CDS NP_872950.1 33151597 1490368 285737..288391 1 NC_002940.2 hypothetical protein 288391 1490368 HD0369 Haemophilus ducreyi 35000HP hypothetical protein NP_872950.1 285737 D 233412 CDS NP_872951.1 33151598 1490369 288423..288932 1 NC_002940.2 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 288932 luxS 1490369 luxS Haemophilus ducreyi 35000HP S-ribosylhomocysteinase NP_872951.1 288423 D 233412 CDS NP_872952.1 33151599 1490370 288999..290624 1 NC_002940.2 hypothetical protein 290624 1490370 HD0371 Haemophilus ducreyi 35000HP hypothetical protein NP_872952.1 288999 D 233412 CDS NP_872953.1 33151600 1490371 complement(290711..291760) 1 NC_002940.2 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 291760 ansB 1490371 ansB Haemophilus ducreyi 35000HP L-asparaginase II NP_872953.1 290711 R 233412 CDS NP_872954.1 33151601 1490372 292034..293671 1 NC_002940.2 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 293671 pyrG 1490372 pyrG Haemophilus ducreyi 35000HP CTP synthetase NP_872954.1 292034 D 233412 CDS NP_872955.1 33151602 1490373 293783..294289 1 NC_002940.2 hypothetical protein 294289 1490373 HD0374 Haemophilus ducreyi 35000HP hypothetical protein NP_872955.1 293783 D 233412 CDS NP_872956.1 33151603 1490374 294325..295125 1 NC_002940.2 glycosyltransferase 295125 1490374 HD0375 Haemophilus ducreyi 35000HP glycosyltransferase NP_872956.1 294325 D 233412 CDS NP_872957.1 33151604 1490375 complement(295204..296175) 1 NC_002940.2 tRNA-dihydrouridine synthase A 296175 1490375 HD0376 Haemophilus ducreyi 35000HP tRNA-dihydrouridine synthase A NP_872957.1 295204 R 233412 CDS NP_872958.1 33151605 1490376 296430..297464 1 NC_002940.2 catalyzes the formation of inosine from adenosine; adenosine deaminase 297464 add 1490376 add Haemophilus ducreyi 35000HP adenosine deaminase NP_872958.1 296430 D 233412 CDS NP_872959.1 33151606 1490377 complement(297566..298165) 1 NC_002940.2 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 298165 1490377 HD0378 Haemophilus ducreyi 35000HP DNA uptake protein NP_872959.1 297566 R 233412 CDS NP_872960.1 33151607 1490378 298640..299971 1 NC_002940.2 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A 299971 nqrA 1490378 nqrA Haemophilus ducreyi 35000HP Na(+)-translocating NADH-quinone reductase subunit A NP_872960.1 298640 D 233412 CDS NP_872961.1 33151608 1490379 299976..301208 1 NC_002940.2 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B 301208 nqrB 1490379 nqrB Haemophilus ducreyi 35000HP Na(+)-translocating NADH-quinone reductase subunit B NP_872961.1 299976 D 233412 CDS NP_872962.1 33151609 1490380 301210..301983 1 NC_002940.2 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C 301983 nqrC 1490380 nqrC Haemophilus ducreyi 35000HP Na(+)-translocating NADH-quinone reductase subunit C NP_872962.1 301210 D 233412 CDS NP_872963.1 33151610 1490381 301983..302606 1 NC_002940.2 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D 302606 nqrD 1490381 nqrD Haemophilus ducreyi 35000HP Na(+)-translocating NADH-quinone reductase subunit D NP_872963.1 301983 D 233412 CDS NP_872964.1 33151611 1490382 302608..303204 1 NC_002940.2 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.; Na(+)-translocating NADH-quinone reductase subunit E 303204 nqrE 1490382 nqrE Haemophilus ducreyi 35000HP Na(+)-translocating NADH-quinone reductase subunit E NP_872964.1 302608 D 233412 CDS NP_872965.1 33151612 1490383 303215..304444 1 NC_002940.2 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F 304444 nqrF 1490383 nqrF Haemophilus ducreyi 35000HP Na(+)-translocating NADH-quinone reductase subunit F NP_872965.1 303215 D 233412 CDS NP_872966.1 33151613 1490384 304613..305641 1 NC_002940.2 thiamine biosynthesis lipoprotein 305641 apbE 1490384 apbE Haemophilus ducreyi 35000HP thiamine biosynthesis lipoprotein NP_872966.1 304613 D 233412 CDS NP_872967.1 33151614 1490385 305653..305901 1 NC_002940.2 hypothetical protein 305901 1490385 HD0387 Haemophilus ducreyi 35000HP hypothetical protein NP_872967.1 305653 D 233412 CDS NP_872968.1 33151615 1490386 complement(305957..308176) 1 NC_002940.2 ton-dependent heme receptor A 308176 tdhA 1490386 tdhA Haemophilus ducreyi 35000HP ton-dependent heme receptor A NP_872968.1 305957 R 233412 CDS NP_872969.1 33151616 1490387 308379..309533 1 NC_002940.2 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 309533 mnmA 1490387 mnmA Haemophilus ducreyi 35000HP tRNA-specific 2-thiouridylase MnmA NP_872969.1 308379 D 233412 CDS NP_872970.1 33151617 1490388 complement(309601..310755) 1 NC_002940.2 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 310755 hcat 1490388 hcat Haemophilus ducreyi 35000HP 3-phenylpropionic acid transporter NP_872970.1 309601 R 233412 CDS NP_872971.1 33151618 1490389 310898..311800 1 NC_002940.2 Required for efficient pilin antigenic variation; recombination associated protein 311800 rdgC 1490389 rdgC Haemophilus ducreyi 35000HP recombination associated protein NP_872971.1 310898 D 233412 CDS NP_872972.1 33151619 1490390 complement(311911..313692) 1 NC_002940.2 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 313692 1490390 HD0393 Haemophilus ducreyi 35000HP anaerobic ribonucleoside triphosphate reductase NP_872972.1 311911 R 233412 CDS NP_872973.1 33151620 1490391 complement(313692..314165) 1 NC_002940.2 hypothetical protein 314165 1490391 HD0394 Haemophilus ducreyi 35000HP hypothetical protein NP_872973.1 313692 R 233412 CDS NP_872974.1 33151621 1490392 314537..315118 1 NC_002940.2 Na(+)-translocating NADH-quinone reductase subunit E 315118 rnfA 1490392 rnfA Haemophilus ducreyi 35000HP Na(+)-translocating NADH-quinone reductase subunit E NP_872974.1 314537 D 233412 CDS NP_872975.1 33151622 1490393 315118..315741 1 NC_002940.2 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 315741 rnfB 1490393 rnfB Haemophilus ducreyi 35000HP electron transport complex protein RnfB NP_872975.1 315118 D 233412 CDS NP_872976.1 33151623 1490394 315734..317842 1 NC_002940.2 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 317842 rnfC 1490394 rnfC Haemophilus ducreyi 35000HP electron transport complex protein RnfC NP_872976.1 315734 D 233412 CDS NP_872977.1 33151624 1490395 317848..318894 1 NC_002940.2 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 318894 rnfD 1490395 rnfD Haemophilus ducreyi 35000HP electron transport complex protein RnfD NP_872977.1 317848 D 233412 CDS NP_872978.1 33151625 1490396 318894..319526 1 NC_002940.2 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 319526 rnfG 1490396 rnfG Haemophilus ducreyi 35000HP electron transport complex protein RnfG NP_872978.1 318894 D 233412 CDS NP_872979.1 33151626 1490397 319526..320209 1 NC_002940.2 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 320209 rnfE 1490397 rnfE Haemophilus ducreyi 35000HP electron transport complex protein RsxE NP_872979.1 319526 D 233412 CDS NP_872980.1 33151627 1490398 320252..321208 1 NC_002940.2 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 321208 lpxM 1490398 lpxM Haemophilus ducreyi 35000HP lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase NP_872980.1 320252 D 233412 CDS NP_872981.1 33151628 1490399 complement(321251..321700) 1 NC_002940.2 hypothetical protein 321700 1490399 HD0405 Haemophilus ducreyi 35000HP hypothetical protein NP_872981.1 321251 R 233412 CDS NP_872982.1 33151629 1490400 complement(321755..322342) 1 NC_002940.2 catalyzes the formation of anthranilate from chorismate and glutamine; functions in tryptophan biosynthesis; anthranilate synthase component II 322342 trpG 1490400 trpG Haemophilus ducreyi 35000HP anthranilate synthase component II NP_872982.1 321755 R 233412 CDS NP_872983.1 33151630 1490401 complement(322323..323951) 1 NC_002940.2 hypothetical protein 323951 1490401 HD0407 Haemophilus ducreyi 35000HP hypothetical protein NP_872983.1 322323 R 233412 CDS NP_872984.1 33151631 1490402 324068..325057 1 NC_002940.2 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; para-aminobenzoate synthase component I 325057 pabB 1490402 pabB Haemophilus ducreyi 35000HP para-aminobenzoate synthase component I NP_872984.1 324068 D 233412 CDS NP_872985.1 33151632 1490403 325035..325634 1 NC_002940.2 hypothetical protein 325634 1490403 HD0409 Haemophilus ducreyi 35000HP hypothetical protein NP_872985.1 325035 D 233412 CDS NP_872986.1 33151633 1490404 325753..326871 1 NC_002940.2 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 326871 recA 1490404 recA Haemophilus ducreyi 35000HP recombinase A NP_872986.1 325753 D 233412 CDS NP_872987.1 33151634 1490405 326950..327405 1 NC_002940.2 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 327405 recX 1490405 recX Haemophilus ducreyi 35000HP recombination regulator RecX NP_872987.1 326950 D 233412 CDS NP_872988.1 33151635 1490406 327398..327706 1 NC_002940.2 hypothetical protein 327706 1490406 HD0412 Haemophilus ducreyi 35000HP hypothetical protein NP_872988.1 327398 D 233412 CDS NP_872989.1 33151636 1490407 327703..328239 1 NC_002940.2 DNA topoisomerase I-related protein 328239 1490407 HD0413 Haemophilus ducreyi 35000HP DNA topoisomerase I-related protein NP_872989.1 327703 D 233412 CDS NP_872990.1 33151637 1490408 328232..328786 1 NC_002940.2 hypothetical protein 328786 1490408 HD0414 Haemophilus ducreyi 35000HP hypothetical protein NP_872990.1 328232 D 233412 CDS NP_872991.1 33151638 1490409 328786..329616 1 NC_002940.2 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 329616 aroE 1490409 aroE Haemophilus ducreyi 35000HP shikimate 5-dehydrogenase NP_872991.1 328786 D 233412 CDS NP_872992.1 33151639 1490410 complement(329609..329806) 1 NC_002940.2 hypothetical protein 329806 1490410 HD0416 Haemophilus ducreyi 35000HP hypothetical protein NP_872992.1 329609 R 233412 CDS NP_872993.1 33151640 1490414 330182..330433 1 NC_002940.2 hypothetical protein 330433 1490414 HD0417 Haemophilus ducreyi 35000HP hypothetical protein NP_872993.1 330182 D 233412 CDS NP_872994.1 33151641 1490415 330472..332115 1 NC_002940.2 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 332115 pgi 1490415 pgi Haemophilus ducreyi 35000HP glucose-6-phosphate isomerase NP_872994.1 330472 D 233412 CDS NP_872995.1 33151642 1490416 complement(332216..333574) 1 NC_002940.2 sodium-dependent transporter 333574 1490416 HD0419 Haemophilus ducreyi 35000HP sodium-dependent transporter NP_872995.1 332216 R 233412 CDS NP_872996.1 33151643 1490417 complement(333655..334491) 1 NC_002940.2 DNA adenine methylase 334491 dam 1490417 dam Haemophilus ducreyi 35000HP DNA adenine methylase NP_872996.1 333655 R 233412 CDS NP_872997.1 33151644 1490418 334401..334511 1 NC_002940.2 hypothetical protein 334511 1490418 HD0421 Haemophilus ducreyi 35000HP hypothetical protein NP_872997.1 334401 D 233412 CDS NP_872998.1 33151645 1490419 complement(334498..335586) 1 NC_002940.2 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 335586 aroB 1490419 aroB Haemophilus ducreyi 35000HP 3-dehydroquinate synthase NP_872998.1 334498 R 233412 CDS NP_872999.1 33151646 1490420 complement(335597..336121) 1 NC_002940.2 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 336121 aroK 1490420 aroK Haemophilus ducreyi 35000HP shikimate kinase NP_872999.1 335597 R 233412 CDS NP_873000.1 33151647 1490421 complement(336150..336275) 1 NC_002940.2 hypothetical protein 336275 1490421 HD0424 Haemophilus ducreyi 35000HP hypothetical protein NP_873000.1 336150 R 233412 CDS NP_873001.1 33151648 1490422 complement(336182..336331) 1 NC_002940.2 hypothetical protein 336331 1490422 HD0425 Haemophilus ducreyi 35000HP hypothetical protein NP_873001.1 336182 R 233412 CDS NP_873002.1 33151649 1490423 complement(336370..338988) 1 NC_002940.2 penicillin-binding protein 1A 338988 mrcA 1490423 mrcA Haemophilus ducreyi 35000HP penicillin-binding protein 1A NP_873002.1 336370 R 233412 CDS NP_873003.1 33151650 1490424 339064..339525 1 NC_002940.2 competence protein A-like protein 339525 comA 1490424 comA Haemophilus ducreyi 35000HP competence protein A-like protein NP_873003.1 339064 D 233412 CDS NP_873004.1 33151651 1490425 339529..339732 1 NC_002940.2 hypothetical protein 339732 1490425 HD0428 Haemophilus ducreyi 35000HP hypothetical protein NP_873004.1 339529 D 233412 CDS NP_873005.1 33151652 1490426 339758..339859 1 NC_002940.2 hypothetical protein 339859 1490426 HD0429 Haemophilus ducreyi 35000HP hypothetical protein NP_873005.1 339758 D 233412 CDS NP_873006.1 33151653 1490427 339831..340055 1 NC_002940.2 hypothetical protein 340055 1490427 HD0430 Haemophilus ducreyi 35000HP hypothetical protein NP_873006.1 339831 D 233412 CDS NP_873007.1 33151654 1490428 340046..340231 1 NC_002940.2 hypothetical protein 340231 1490428 HD0431 Haemophilus ducreyi 35000HP hypothetical protein NP_873007.1 340046 D 233412 CDS NP_873008.1 33151655 1490429 340212..340754 1 NC_002940.2 hypothetical protein 340754 1490429 HD0432 Haemophilus ducreyi 35000HP hypothetical protein NP_873008.1 340212 D 233412 CDS NP_873009.1 33151656 1490430 340757..341152 1 NC_002940.2 hypothetical protein 341152 1490430 HD0433 Haemophilus ducreyi 35000HP hypothetical protein NP_873009.1 340757 D 233412 CDS NP_873010.1 33151657 1490431 341162..342421 1 NC_002940.2 competence protein E 342421 comE 1490431 comE Haemophilus ducreyi 35000HP competence protein E NP_873010.1 341162 D 233412 CDS NP_873011.1 33151658 1490432 342591..343004 1 NC_002940.2 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 343004 nusB 1490432 nusB Haemophilus ducreyi 35000HP transcription antitermination protein NusB NP_873011.1 342591 D 233412 CDS NP_873012.1 33151659 1490433 343061..344026 1 NC_002940.2 thiamin-monophosphate kinase 344026 thiL 1490433 thiL Haemophilus ducreyi 35000HP thiamin-monophosphate kinase NP_873012.1 343061 D 233412 CDS NP_873013.1 33151660 1490434 344019..344501 1 NC_002940.2 phosphatidylglycerophosphatase A 344501 pgpA 1490434 pgpA Haemophilus ducreyi 35000HP phosphatidylglycerophosphatase A NP_873013.1 344019 D 233412 CDS NP_873014.1 33151661 1490435 complement(344631..345680) 1 NC_002940.2 tRNA/rRNA methyltransferase 345680 1490435 HD0438 Haemophilus ducreyi 35000HP tRNA/rRNA methyltransferase NP_873014.1 344631 R 233412 CDS NP_873015.1 33151662 1490436 345820..346632 1 NC_002940.2 inositol monophosphatase 346632 suhB 1490436 suhB Haemophilus ducreyi 35000HP inositol monophosphatase NP_873015.1 345820 D 233412 CDS NP_873016.1 33151663 1490437 346704..348557 1 NC_002940.2 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 348557 dxs 1490437 dxs Haemophilus ducreyi 35000HP 1-deoxy-D-xylulose-5-phosphate synthase NP_873016.1 346704 D 233412 CDS NP_873017.1 33151664 1490439 complement(349730..350809) 1 NC_002940.2 DAHP synthetase, tyrosine repressible; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 350809 aroF 1490439 aroF Haemophilus ducreyi 35000HP phospho-2-dehydro-3-deoxyheptonate aldolase NP_873017.1 349730 R 233412 CDS NP_873018.1 33151665 1490440 complement(350849..351895) 1 NC_002940.2 ADP-heptose--lipooligosaccharide heptosyltransferase I 351895 1490440 HD0445 Haemophilus ducreyi 35000HP ADP-heptose--lipooligosaccharide heptosyltransferase I NP_873018.1 350849 R 233412 CDS NP_873019.1 33151666 1490441 complement(351995..353434) 1 NC_002940.2 pyruvate kinase II 353434 pykA 1490441 pykA Haemophilus ducreyi 35000HP pyruvate kinase II NP_873019.1 351995 R 233412 CDS NP_873020.1 33151667 1490442 353555..354043 1 NC_002940.2 phosphohistidine phosphatase 354043 sixA 1490442 sixA Haemophilus ducreyi 35000HP phosphohistidine phosphatase NP_873020.1 353555 D 233412 CDS NP_873021.1 33151668 1490443 354269..355231 1 NC_002940.2 dehydrogenase 355231 1490443 HD0448 Haemophilus ducreyi 35000HP dehydrogenase NP_873021.1 354269 D 233412 CDS NP_873022.1 33151669 1490444 355260..355556 1 NC_002940.2 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 355556 fis 1490444 fis Haemophilus ducreyi 35000HP DNA-binding protein Fis NP_873022.1 355260 D 233412 CDS NP_873023.1 33151670 1490445 complement(355684..356715) 1 NC_002940.2 N-acetylmuramoyl-L-alanine amidase 356715 amiB 1490445 amiB Haemophilus ducreyi 35000HP N-acetylmuramoyl-L-alanine amidase NP_873023.1 355684 R 233412 CDS NP_873024.1 33151671 1490446 complement(356730..357230) 1 NC_002940.2 hypothetical protein 357230 1490446 HD0451 Haemophilus ducreyi 35000HP hypothetical protein NP_873024.1 356730 R 233412 CDS NP_873025.1 33151672 1490447 complement(357272..357823) 1 NC_002940.2 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 357823 orn 1490447 orn Haemophilus ducreyi 35000HP oligoribonuclease NP_873025.1 357272 R 233412 CDS NP_873026.1 33151673 1490448 complement(357816..358301) 1 NC_002940.2 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 358301 coaD 1490448 coaD Haemophilus ducreyi 35000HP phosphopantetheine adenylyltransferase NP_873026.1 357816 R 233412 CDS NP_873027.1 33151674 1490449 complement(358304..359587) 1 NC_002940.2 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 359587 waaA 1490449 waaA Haemophilus ducreyi 35000HP 3-deoxy-D-manno-octulosonic-acid transferase NP_873027.1 358304 R 233412 CDS NP_873028.1 33151675 1490450 complement(359731..361134) 1 NC_002940.2 protease 361134 1490450 HD0455 Haemophilus ducreyi 35000HP protease NP_873028.1 359731 R 233412 CDS NP_873029.1 33151676 1490451 361279..361674 1 NC_002940.2 hypothetical protein 361674 1490451 HD0457 Haemophilus ducreyi 35000HP hypothetical protein NP_873029.1 361279 D 233412 CDS NP_873030.1 33151677 1490452 361782..361904 1 NC_002940.2 hypothetical protein 361904 1490452 HD0458 Haemophilus ducreyi 35000HP hypothetical protein NP_873030.1 361782 D 233412 CDS NP_873031.1 33151678 1490453 361928..362827 1 NC_002940.2 hypothetical protein 362827 1490453 HD0459 Haemophilus ducreyi 35000HP hypothetical protein NP_873031.1 361928 D 233412 CDS NP_873032.1 33151679 1490454 363074..363214 1 NC_002940.2 hypothetical protein 363214 1490454 HD0460 Haemophilus ducreyi 35000HP hypothetical protein NP_873032.1 363074 D 233412 CDS NP_873033.1 33151680 1490455 363278..364645 1 NC_002940.2 amino-acid transporter sodium-dependent 364645 1490455 HD0461 Haemophilus ducreyi 35000HP amino-acid transporter sodium-dependent NP_873033.1 363278 D 233412 CDS NP_873034.1 33151681 1490456 364725..364823 1 NC_002940.2 hypothetical protein 364823 1490456 HD0463 Haemophilus ducreyi 35000HP hypothetical protein NP_873034.1 364725 D 233412 CDS NP_873035.1 33151682 1490457 364820..366022 1 NC_002940.2 aminotransferase 366022 1490457 HD0464 Haemophilus ducreyi 35000HP aminotransferase NP_873035.1 364820 D 233412 CDS NP_873036.1 33151683 1490458 366131..367105 1 NC_002940.2 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 367105 pfkA 1490458 pfkA Haemophilus ducreyi 35000HP 6-phosphofructokinase NP_873036.1 366131 D 233412 CDS NP_873037.1 33151684 1490459 367222..368214 1 NC_002940.2 lipooligosaccharide N-acetylglucosamine glycosyltransferase 368214 lgtA 1490459 lgtA Haemophilus ducreyi 35000HP lipooligosaccharide N-acetylglucosamine glycosyltransferase NP_873037.1 367222 D 233412 CDS NP_873038.1 33151685 1490460 368257..368967 1 NC_002940.2 hypothetical protein 368967 1490460 HD0467 Haemophilus ducreyi 35000HP hypothetical protein NP_873038.1 368257 D 233412 CDS NP_873039.1 33151686 1490461 complement(368975..369952) 1 NC_002940.2 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 369952 rluD 1490461 rluD Haemophilus ducreyi 35000HP 23S rRNA pseudouridine synthase D NP_873039.1 368975 R 233412 CDS NP_873040.1 33151687 1490462 370106..370888 1 NC_002940.2 lipoprotein 370888 1490462 HD0470 Haemophilus ducreyi 35000HP lipoprotein NP_873040.1 370106 D 233412 CDS NP_873041.1 33151688 1490463 370973..372019 1 NC_002940.2 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 372019 gcp 1490463 gcp Haemophilus ducreyi 35000HP DNA-binding/iron metalloprotein/AP endonuclease NP_873041.1 370973 D 233412 CDS NP_873042.1 33151689 1490464 372034..372876 1 NC_002940.2 lipooligosaccharide galactosyltransferase II 372876 lgtB 1490464 lgtB Haemophilus ducreyi 35000HP lipooligosaccharide galactosyltransferase II NP_873042.1 372034 D 233412 CDS NP_873043.1 33151690 1490466 373282..375087 1 NC_002940.2 ATP-dependent DNA helicase 375087 recQ 1490466 recQ Haemophilus ducreyi 35000HP ATP-dependent DNA helicase NP_873043.1 373282 D 233412 CDS NP_873044.1 33151691 1490467 complement(375156..376457) 1 NC_002940.2 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 376457 eno 1490467 eno Haemophilus ducreyi 35000HP phosphopyruvate hydratase NP_873044.1 375156 R 233412 CDS NP_873045.1 33151692 1490468 complement(376645..377286) 1 NC_002940.2 Catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA (uracil-5-)-methyltransferase 377286 1490468 HD0478 Haemophilus ducreyi 35000HP 23S rRNA (uracil-5-)-methyltransferase NP_873045.1 376645 R 233412 CDS NP_873046.1 33151693 1490469 complement(377702..378544) 1 NC_002940.2 DNA-binding protein 378544 1490469 HD0479 Haemophilus ducreyi 35000HP DNA-binding protein NP_873046.1 377702 R 233412 CDS NP_873047.1 33151694 1490470 378623..378886 1 NC_002940.2 hypothetical protein 378886 1490470 HD0480 Haemophilus ducreyi 35000HP hypothetical protein NP_873047.1 378623 D 233412 CDS NP_873048.1 33151695 1490472 complement(380852..381094) 1 NC_002940.2 hypothetical protein 381094 1490472 HD0483 Haemophilus ducreyi 35000HP hypothetical protein NP_873048.1 380852 R 233412 CDS NP_873049.1 33151696 1490474 382034..382240 1 NC_002940.2 hypothetical protein 382240 1490474 HD0486 Haemophilus ducreyi 35000HP hypothetical protein NP_873049.1 382034 D 233412 CDS NP_873050.1 33151697 1490475 382227..382571 1 NC_002940.2 hypothetical protein 382571 1490475 HD0488 Haemophilus ducreyi 35000HP hypothetical protein NP_873050.1 382227 D 233412 CDS NP_873051.1 33151698 1490476 382582..383199 1 NC_002940.2 hypothetical protein 383199 1490476 HD0489 Haemophilus ducreyi 35000HP hypothetical protein NP_873051.1 382582 D 233412 CDS NP_873052.1 33151699 1490477 383253..383501 1 NC_002940.2 hypothetical protein 383501 1490477 HD0490 Haemophilus ducreyi 35000HP hypothetical protein NP_873052.1 383253 D 233412 CDS NP_873053.1 33151700 1490478 383505..383684 1 NC_002940.2 hypothetical protein 383684 1490478 HD0492 Haemophilus ducreyi 35000HP hypothetical protein NP_873053.1 383505 D 233412 CDS NP_873054.1 33151701 1490479 383703..383999 1 NC_002940.2 hypothetical protein 383999 1490479 HD0493 Haemophilus ducreyi 35000HP hypothetical protein NP_873054.1 383703 D 233412 CDS NP_873055.1 33151702 1490480 383996..384199 1 NC_002940.2 hypothetical protein 384199 1490480 HD0494 Haemophilus ducreyi 35000HP hypothetical protein NP_873055.1 383996 D 233412 CDS NP_873056.1 33151703 1490481 384200..384478 1 NC_002940.2 hypothetical protein 384478 1490481 HD0495 Haemophilus ducreyi 35000HP hypothetical protein NP_873056.1 384200 D 233412 CDS NP_873057.1 33151704 1490482 384518..385102 1 NC_002940.2 hypothetical protein 385102 1490482 HD0496 Haemophilus ducreyi 35000HP hypothetical protein NP_873057.1 384518 D 233412 CDS NP_873058.1 33151705 1490483 385086..385514 1 NC_002940.2 hypothetical protein 385514 1490483 HD0497 Haemophilus ducreyi 35000HP hypothetical protein NP_873058.1 385086 D 233412 CDS NP_873059.1 33151706 1490484 385828..386427 1 NC_002940.2 phage anti-repressor protein 386427 1490484 HD0498 Haemophilus ducreyi 35000HP phage anti-repressor protein NP_873059.1 385828 D 233412 CDS NP_873060.1 33151707 1490485 386438..386647 1 NC_002940.2 hypothetical protein 386647 1490485 HD0499 Haemophilus ducreyi 35000HP hypothetical protein NP_873060.1 386438 D 233412 CDS NP_873061.1 33151708 1490486 386776..387198 1 NC_002940.2 hypothetical protein 387198 1490486 HD0500 Haemophilus ducreyi 35000HP hypothetical protein NP_873061.1 386776 D 233412 CDS NP_873062.1 33151709 1490487 387199..387834 1 NC_002940.2 N-acetylmuramoyl-L-alanine amidase 387834 1490487 HD0501 Haemophilus ducreyi 35000HP N-acetylmuramoyl-L-alanine amidase NP_873062.1 387199 D 233412 CDS NP_873063.1 33151710 1490488 387839..388192 1 NC_002940.2 hypothetical protein 388192 1490488 HD0502 Haemophilus ducreyi 35000HP hypothetical protein NP_873063.1 387839 D 233412 CDS NP_873064.1 33151711 1490489 388179..388412 1 NC_002940.2 hypothetical protein 388412 1490489 HD0503 Haemophilus ducreyi 35000HP hypothetical protein NP_873064.1 388179 D 233412 CDS NP_873065.1 33151712 1490490 388412..388801 1 NC_002940.2 hypothetical protein 388801 1490490 HD0504 Haemophilus ducreyi 35000HP hypothetical protein NP_873065.1 388412 D 233412 CDS NP_873066.1 33151713 1490491 388850..389128 1 NC_002940.2 hypothetical protein 389128 1490491 HD0506 Haemophilus ducreyi 35000HP hypothetical protein NP_873066.1 388850 D 233412 CDS NP_873067.1 33151714 1490492 389125..389379 1 NC_002940.2 hypothetical protein 389379 1490492 HD0507 Haemophilus ducreyi 35000HP hypothetical protein NP_873067.1 389125 D 233412 CDS NP_873068.1 33151715 1490493 389387..389887 1 NC_002940.2 DNA-binding protein 389887 1490493 HD0509 Haemophilus ducreyi 35000HP DNA-binding protein NP_873068.1 389387 D 233412 CDS NP_873069.1 33151716 1490494 389887..389982 1 NC_002940.2 hypothetical protein 389982 1490494 HD0510 Haemophilus ducreyi 35000HP hypothetical protein NP_873069.1 389887 D 233412 CDS NP_873070.1 33151717 1490496 391626..393263 1 NC_002940.2 hypothetical protein 393263 1490496 HD0514 Haemophilus ducreyi 35000HP hypothetical protein NP_873070.1 391626 D 233412 CDS NP_873071.1 33151718 1490497 393247..394557 1 NC_002940.2 hypothetical protein 394557 1490497 HD0515 Haemophilus ducreyi 35000HP hypothetical protein NP_873071.1 393247 D 233412 CDS NP_873072.1 33151719 1490498 394690..395106 1 NC_002940.2 mu-like bacteriophage G protein 2 395106 mug-2 1490498 mug-2 Haemophilus ducreyi 35000HP mu-like bacteriophage G protein 2 NP_873072.1 394690 D 233412 CDS NP_873073.1 33151720 1490499 395346..396431 1 NC_002940.2 bacteriophage Mu I protein GP32 396431 1490499 HD0518 Haemophilus ducreyi 35000HP bacteriophage Mu I protein GP32 NP_873073.1 395346 D 233412 CDS NP_873074.1 33151721 1490500 396431..397354 1 NC_002940.2 bacteriophage mu T protein 397354 1490500 HD0519 Haemophilus ducreyi 35000HP bacteriophage mu T protein NP_873074.1 396431 D 233412 CDS NP_873075.1 33151722 1490501 397401..397688 1 NC_002940.2 hypothetical protein 397688 1490501 HD0520 Haemophilus ducreyi 35000HP hypothetical protein NP_873075.1 397401 D 233412 CDS NP_873076.1 33151723 1490502 397691..398077 1 NC_002940.2 hypothetical protein 398077 1490502 HD0521 Haemophilus ducreyi 35000HP hypothetical protein NP_873076.1 397691 D 233412 CDS NP_873077.1 33151724 1490503 398074..398520 1 NC_002940.2 hypothetical protein 398520 1490503 HD0522 Haemophilus ducreyi 35000HP hypothetical protein NP_873077.1 398074 D 233412 CDS NP_873078.1 33151725 1490504 398550..399293 1 NC_002940.2 hypothetical protein 399293 1490504 HD0523 Haemophilus ducreyi 35000HP hypothetical protein NP_873078.1 398550 D 233412 CDS NP_873079.1 33151726 1490505 399351..399770 1 NC_002940.2 hypothetical protein 399770 1490505 HD0525 Haemophilus ducreyi 35000HP hypothetical protein NP_873079.1 399351 D 233412 CDS NP_873080.1 33151727 1490506 complement(399947..400201) 1 NC_002940.2 hypothetical protein 400201 1490506 HD0526 Haemophilus ducreyi 35000HP hypothetical protein NP_873080.1 399947 R 233412 CDS NP_873081.1 33151728 1490507 400216..403575 1 NC_002940.2 tail length tape measure protein 403575 1490507 HD0527 Haemophilus ducreyi 35000HP tail length tape measure protein NP_873081.1 400216 D 233412 CDS NP_873082.1 33151729 1490508 403575..404573 1 NC_002940.2 hypothetical protein 404573 1490508 HD0529 Haemophilus ducreyi 35000HP hypothetical protein NP_873082.1 403575 D 233412 CDS NP_873083.1 33151730 1490509 404576..405475 1 NC_002940.2 hypothetical protein 405475 1490509 HD0530 Haemophilus ducreyi 35000HP hypothetical protein NP_873083.1 404576 D 233412 CDS NP_873084.1 33151731 1490510 405541..406230 1 NC_002940.2 hypothetical protein 406230 1490510 HD0531 Haemophilus ducreyi 35000HP hypothetical protein NP_873084.1 405541 D 233412 CDS NP_873085.1 33151732 1490511 406236..407222 1 NC_002940.2 hypothetical protein 407222 1490511 HD0532 Haemophilus ducreyi 35000HP hypothetical protein NP_873085.1 406236 D 233412 CDS NP_873086.1 33151733 1490512 407267..407791 1 NC_002940.2 hypothetical protein 407791 1490512 HD0533 Haemophilus ducreyi 35000HP hypothetical protein NP_873086.1 407267 D 233412 CDS NP_873087.1 33151734 1490513 407794..408075 1 NC_002940.2 hypothetical protein 408075 1490513 HD0534 Haemophilus ducreyi 35000HP hypothetical protein NP_873087.1 407794 D 233412 CDS NP_873088.1 33151735 1490514 408088..408339 1 NC_002940.2 hypothetical protein 408339 1490514 HD0535 Haemophilus ducreyi 35000HP hypothetical protein NP_873088.1 408088 D 233412 CDS NP_873089.1 33151736 1490515 408357..408560 1 NC_002940.2 hypothetical protein 408560 1490515 HD0536 Haemophilus ducreyi 35000HP hypothetical protein NP_873089.1 408357 D 233412 CDS NP_873090.1 33151737 1490516 408560..411349 1 NC_002940.2 hypothetical protein 411349 1490516 HD0538 Haemophilus ducreyi 35000HP hypothetical protein NP_873090.1 408560 D 233412 CDS NP_873091.1 33151738 1490517 411500..411901 1 NC_002940.2 hypothetical protein 411901 1490517 HD0539 Haemophilus ducreyi 35000HP hypothetical protein NP_873091.1 411500 D 233412 CDS NP_873092.1 33151739 1490518 complement(411956..412066) 1 NC_002940.2 hypothetical protein 412066 1490518 HD0540 Haemophilus ducreyi 35000HP hypothetical protein NP_873092.1 411956 R 233412 CDS NP_873093.1 33151740 1490520 complement(412800..413834) 1 NC_002940.2 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 413834 nagZ 1490520 nagZ Haemophilus ducreyi 35000HP beta-hexosaminidase NP_873093.1 412800 R 233412 CDS NP_873094.1 33151741 1490521 complement(413865..414545) 1 NC_002940.2 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 414545 mutH 1490521 mutH Haemophilus ducreyi 35000HP DNA mismatch repair protein NP_873094.1 413865 R 233412 CDS NP_873095.1 33151742 1490522 complement(414589..415224) 1 NC_002940.2 Represses a number of genes involved in the response to DNA damage; LexA repressor 415224 lexA 1490522 lexA Haemophilus ducreyi 35000HP LexA repressor NP_873095.1 414589 R 233412 CDS NP_873096.1 33151743 1490523 415387..417822 1 NC_002940.2 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 417822 plsB 1490523 plsB Haemophilus ducreyi 35000HP glycerol-3-phosphate acyltransferase NP_873096.1 415387 D 233412 CDS NP_873097.1 33151744 1490524 417929..419110 1 NC_002940.2 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 419110 purT 1490524 purT Haemophilus ducreyi 35000HP phosphoribosylglycinamide formyltransferase 2 NP_873097.1 417929 D 233412 CDS NP_873098.1 33151745 1490525 complement(419178..422654) 1 NC_002940.2 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 422654 dnaE 1490525 dnaE Haemophilus ducreyi 35000HP DNA polymerase III subunit alpha NP_873098.1 419178 R 233412 CDS NP_873099.1 33151746 1490526 complement(422766..423848) 1 NC_002940.2 hypothetical protein 423848 1490526 HD0552 Haemophilus ducreyi 35000HP hypothetical protein NP_873099.1 422766 R 233412 CDS NP_873100.1 33151747 1490527 complement(423849..424952) 1 NC_002940.2 hypothetical protein 424952 1490527 HD0553 Haemophilus ducreyi 35000HP hypothetical protein NP_873100.1 423849 R 233412 CDS NP_873101.1 33151748 1490528 425042..425197 1 NC_002940.2 hypothetical protein 425197 1490528 HD0554 Haemophilus ducreyi 35000HP hypothetical protein NP_873101.1 425042 D 233412 CDS NP_873102.1 33151749 1490529 425279..426778 1 NC_002940.2 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 426778 pepA 1490529 pepA Haemophilus ducreyi 35000HP leucyl aminopeptidase NP_873102.1 425279 D 233412 CDS NP_873103.1 33151750 1490530 complement(426848..427477) 1 NC_002940.2 hypothetical protein 427477 1490530 HD0556 Haemophilus ducreyi 35000HP hypothetical protein NP_873103.1 426848 R 233412 CDS NP_873104.1 33151751 1490531 complement(427477..427899) 1 NC_002940.2 6-pyruvoyl tetrahydrobiopterin synthase 427899 1490531 HD0557 Haemophilus ducreyi 35000HP 6-pyruvoyl tetrahydrobiopterin synthase NP_873104.1 427477 R 233412 CDS NP_873105.1 33151752 1490532 complement(427892..428566) 1 NC_002940.2 hypothetical protein 428566 1490532 HD0558 Haemophilus ducreyi 35000HP hypothetical protein NP_873105.1 427892 R 233412 CDS NP_873106.1 33151753 1490533 complement(428576..428761) 1 NC_002940.2 hypothetical protein 428761 1490533 HD0560 Haemophilus ducreyi 35000HP hypothetical protein NP_873106.1 428576 R 233412 CDS NP_873107.1 33151754 1490534 428786..428884 1 NC_002940.2 hypothetical protein 428884 1490534 HD0559 Haemophilus ducreyi 35000HP hypothetical protein NP_873107.1 428786 D 233412 CDS NP_873108.1 33151755 1490535 428931..429842 1 NC_002940.2 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 429842 purM 1490535 purM Haemophilus ducreyi 35000HP phosphoribosylaminoimidazole synthetase NP_873108.1 428931 D 233412 CDS NP_873109.1 33151756 1490536 429944..430231 1 NC_002940.2 hypothetical protein 430231 1490536 HD0563 Haemophilus ducreyi 35000HP hypothetical protein NP_873109.1 429944 D 233412 CDS NP_873110.1 33151757 1490537 430360..431787 1 NC_002940.2 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 431787 aspA 1490537 aspA Haemophilus ducreyi 35000HP aspartate ammonia-lyase NP_873110.1 430360 D 233412 CDS NP_873111.1 33151758 1490538 complement(431865..434435) 1 NC_002940.2 ATP-dependent Clp protease subunit B 434435 clpB 1490538 clpB Haemophilus ducreyi 35000HP ATP-dependent Clp protease subunit B NP_873111.1 431865 R 233412 CDS NP_873112.1 33151759 1490539 complement(434657..435679) 1 NC_002940.2 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 435679 argE 1490539 argE Haemophilus ducreyi 35000HP acetylornithine deacetylase NP_873112.1 434657 R 233412 CDS NP_873113.1 33151760 1490540 complement(435672..435767) 1 NC_002940.2 hypothetical protein 435767 1490540 HD0567 Haemophilus ducreyi 35000HP hypothetical protein NP_873113.1 435672 R 233412 CDS NP_873114.1 33151761 1490541 complement(435736..437136) 1 NC_002940.2 arginine/ornithine antiporter protein 437136 arcD 1490541 arcD Haemophilus ducreyi 35000HP arginine/ornithine antiporter protein NP_873114.1 435736 R 233412 CDS NP_873115.2 161511521 1490542 437428..438573 1 NC_002940.2 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 438573 metK 1490542 metK Haemophilus ducreyi 35000HP S-adenosylmethionine synthetase NP_873115.2 437428 D 233412 CDS NP_873116.1 33151763 1490543 438648..439400 1 NC_002940.2 TatD family deoxyribonuclease 439400 1490543 HD0570 Haemophilus ducreyi 35000HP TatD family deoxyribonuclease NP_873116.1 438648 D 233412 CDS NP_873117.1 33151764 1490544 complement(439517..441535) 1 NC_002940.2 ATP-dependent DNA helicase 441535 rep 1490544 rep Haemophilus ducreyi 35000HP ATP-dependent DNA helicase NP_873117.1 439517 R 233412 CDS NP_873118.1 33151765 1490545 441823..442938 1 NC_002940.2 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 442938 potA 1490545 potA Haemophilus ducreyi 35000HP putrescine/spermidine ABC transporter ATPase NP_873118.1 441823 D 233412 CDS NP_873119.1 33151766 1490546 442925..443791 1 NC_002940.2 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 443791 potB 1490546 potB Haemophilus ducreyi 35000HP spermidine/putrescine ABC transporter membrane protein NP_873119.1 442925 D 233412 CDS NP_873120.1 33151767 1490547 443791..444558 1 NC_002940.2 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 444558 potC 1490547 potC Haemophilus ducreyi 35000HP spermidine/putrescine ABC transporter membrane protein NP_873120.1 443791 D 233412 CDS NP_873121.1 33151768 1490548 complement(444654..445709) 1 NC_002940.2 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 445709 prfB 1490548 prfB Haemophilus ducreyi 35000HP peptide chain release factor 2 NP_873121.1 444654 R 233412 CDS NP_873122.1 33151769 1490549 445959..446930 1 NC_002940.2 selenophosphate synthetase; selenide, water dikinase 446930 selD 1490549 selD Haemophilus ducreyi 35000HP selenide, water dikinase NP_873122.1 445959 D 233412 CDS NP_873123.1 33151770 1490551 complement(448196..448825) 1 NC_002940.2 lipoprotein Hlp 448825 hlp 1490551 hlp Haemophilus ducreyi 35000HP lipoprotein Hlp NP_873123.1 448196 R 233412 CDS NP_873124.1 33151771 1490552 complement(448883..449365) 1 NC_002940.2 lipoprotein HlpB 449365 HlpB 1490552 HlpB Haemophilus ducreyi 35000HP lipoprotein HlpB NP_873124.1 448883 R 233412 CDS NP_873125.1 33151772 1490553 complement(449515..450696) 1 NC_002940.2 monoxygenase 450696 visC 1490553 visC Haemophilus ducreyi 35000HP monoxygenase NP_873125.1 449515 R 233412 CDS NP_873126.1 33151773 1490554 complement(450741..451604) 1 NC_002940.2 hypothetical protein 451604 1490554 HD0584 Haemophilus ducreyi 35000HP hypothetical protein NP_873126.1 450741 R 233412 CDS NP_873127.1 33151774 1490555 complement(451624..452148) 1 NC_002940.2 PTS system, nitrogen regulatory IIA-like protein 452148 ptsN 1490555 ptsN Haemophilus ducreyi 35000HP PTS system, nitrogen regulatory IIA-like protein NP_873127.1 451624 R 233412 CDS NP_873128.1 33151775 1490556 complement(452181..452906) 1 NC_002940.2 ABC transporter ATP-binding protein 452906 1490556 HD0586 Haemophilus ducreyi 35000HP ABC transporter ATP-binding protein NP_873128.1 452181 R 233412 CDS NP_873129.1 33151776 1490557 complement(452915..453418) 1 NC_002940.2 hypothetical protein 453418 1490557 HD0587 Haemophilus ducreyi 35000HP hypothetical protein NP_873129.1 452915 R 233412 CDS NP_873130.1 33151777 1490558 complement(453451..454032) 1 NC_002940.2 hypothetical protein 454032 1490558 HD0588 Haemophilus ducreyi 35000HP hypothetical protein NP_873130.1 453451 R 233412 CDS NP_873131.1 33151778 1490559 complement(454201..454971) 1 NC_002940.2 hypothetical protein 454971 1490559 HD0589 Haemophilus ducreyi 35000HP hypothetical protein NP_873131.1 454201 R 233412 CDS NP_873132.1 33151779 1490560 complement(454968..455417) 1 NC_002940.2 hypothetical protein 455417 1490560 HD0590 Haemophilus ducreyi 35000HP hypothetical protein NP_873132.1 454968 R 233412 CDS NP_873133.1 33151780 1490561 complement(455487..456071) 1 NC_002940.2 hypothetical protein 456071 1490561 HD0591 Haemophilus ducreyi 35000HP hypothetical protein NP_873133.1 455487 R 233412 CDS NP_873134.1 33151781 1490562 complement(456113..456253) 1 NC_002940.2 hypothetical protein 456253 1490562 HD0592 Haemophilus ducreyi 35000HP hypothetical protein NP_873134.1 456113 R 233412 CDS NP_873135.1 33151782 1490563 complement(456253..456831) 1 NC_002940.2 Holliday junction nuclease; endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 456831 ruvC 1490563 ruvC Haemophilus ducreyi 35000HP Holliday junction resolvase NP_873135.1 456253 R 233412 CDS NP_873136.1 33151783 1490564 complement(456914..457447) 1 NC_002940.2 hypothetical protein 457447 1490564 HD0595 Haemophilus ducreyi 35000HP hypothetical protein NP_873136.1 456914 R 233412 CDS NP_873137.1 33151784 1490565 complement(457527..458267) 1 NC_002940.2 hypothetical protein 458267 1490565 HD0596 Haemophilus ducreyi 35000HP hypothetical protein NP_873137.1 457527 R 233412 CDS NP_873138.1 33151785 1490566 complement(458348..458803) 1 NC_002940.2 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 458803 ntpA 1490566 ntpA Haemophilus ducreyi 35000HP dATP pyrophosphohydrolase NP_873138.1 458348 R 233412 CDS NP_873139.1 33151786 1490567 458784..458903 1 NC_002940.2 hypothetical protein 458903 1490567 HD0597 Haemophilus ducreyi 35000HP hypothetical protein NP_873139.1 458784 D 233412 CDS NP_873140.1 33151787 1490568 complement(458909..460678) 1 NC_002940.2 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 460678 aspS 1490568 aspS Haemophilus ducreyi 35000HP aspartyl-tRNA synthetase NP_873140.1 458909 R 233412 CDS NP_873141.1 33151788 1490569 complement(460870..461856) 1 NC_002940.2 hypothetical protein 461856 1490569 HD0600 Haemophilus ducreyi 35000HP hypothetical protein NP_873141.1 460870 R 233412 CDS NP_873142.1 33151789 1490570 462241..463209 1 NC_002940.2 thiamine-binding periplasmic protein 463209 tbpA 1490570 tbpA Haemophilus ducreyi 35000HP thiamine-binding periplasmic protein NP_873142.1 462241 D 233412 CDS NP_873143.1 33151790 1490571 463188..463340 1 NC_002940.2 hypothetical protein 463340 1490571 HD0602 Haemophilus ducreyi 35000HP hypothetical protein NP_873143.1 463188 D 233412 CDS NP_873144.1 33151791 1490572 463406..463855 1 NC_002940.2 dosage-dependent DnaK suppressor protein 463855 dksA 1490572 dksA Haemophilus ducreyi 35000HP dosage-dependent DnaK suppressor protein NP_873144.1 463406 D 233412 CDS NP_873145.1 33151792 1490573 463910..465481 1 NC_002940.2 polynucleotide adenylyltransferase; polyA polymerase 465481 pcnB 1490573 pcnB Haemophilus ducreyi 35000HP polyA polymerase NP_873145.1 463910 D 233412 CDS NP_873146.1 33151793 1490574 465551..466036 1 NC_002940.2 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 466036 folK 1490574 folK Haemophilus ducreyi 35000HP 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase NP_873146.1 465551 D 233412 CDS NP_873147.1 33151794 1490575 complement(466046..466291) 1 NC_002940.2 hypothetical protein 466291 1490575 HD0606 Haemophilus ducreyi 35000HP hypothetical protein NP_873147.1 466046 R 233412 CDS NP_873148.1 33151795 1490576 complement(466284..469007) 1 NC_002940.2 hypothetical protein 469007 1490576 HD0607 Haemophilus ducreyi 35000HP hypothetical protein NP_873148.1 466284 R 233412 CDS NP_873149.1 33151796 1490577 complement(469102..469263) 1 NC_002940.2 hypothetical protein 469263 1490577 HD0608 Haemophilus ducreyi 35000HP hypothetical protein NP_873149.1 469102 R 233412 CDS NP_873150.1 33151797 1490578 complement(469113..469832) 1 NC_002940.2 hypothetical protein 469832 1490578 HD0609 Haemophilus ducreyi 35000HP hypothetical protein NP_873150.1 469113 R 233412 CDS NP_873151.1 33151798 1490579 469916..470323 1 NC_002940.2 lactoylglutathione lyase 470323 gloA 1490579 gloA Haemophilus ducreyi 35000HP lactoylglutathione lyase NP_873151.1 469916 D 233412 CDS NP_873152.1 33151799 1490580 470479..471123 1 NC_002940.2 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 471123 rnt 1490580 rnt Haemophilus ducreyi 35000HP ribonuclease T NP_873152.1 470479 D 233412 CDS NP_873153.1 33151800 1490581 complement(471320..472537) 1 NC_002940.2 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 472537 fabB 1490581 fabB Haemophilus ducreyi 35000HP 3-oxoacyl-ACP synthase NP_873153.1 471320 R 233412 CDS NP_873154.1 33151801 1490582 472900..475314 1 NC_002940.2 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 475314 cyaA 1490582 cyaA Haemophilus ducreyi 35000HP adenylate cyclase NP_873154.1 472900 D 233412 CDS NP_873155.1 33151802 1490583 475463..477343 1 NC_002940.2 glutathione-regulated potassium-efflux system protein 477343 kefB 1490583 kefB Haemophilus ducreyi 35000HP glutathione-regulated potassium-efflux system protein NP_873155.1 475463 D 233412 CDS NP_873156.1 33151803 1490584 477456..479351 1 NC_002940.2 cytochrome c-type biogenesis protein 479351 nfrE 1490584 nfrE Haemophilus ducreyi 35000HP cytochrome c-type biogenesis protein NP_873156.1 477456 D 233412 CDS NP_873157.1 33151804 1490585 479353..479889 1 NC_002940.2 thiol:disulfide interchange protein DsbE 479889 dsbE2 1490585 dsbE2 Haemophilus ducreyi 35000HP thiol:disulfide interchange protein DsbE NP_873157.1 479353 D 233412 CDS NP_873158.1 33151805 1490587 481162..481686 1 NC_002940.2 heme binding protein 481686 hugZ 1490587 hugZ Haemophilus ducreyi 35000HP heme binding protein NP_873158.1 481162 D 233412 CDS NP_873159.1 33151806 1490588 complement(481863..483140) 1 NC_002940.2 synthesizes isochorismate acid from chorismate; menaquinone-specific isochorismate synthase 483140 menF 1490588 menF Haemophilus ducreyi 35000HP menaquinone-specific isochorismate synthase NP_873159.1 481863 R 233412 CDS NP_873160.1 33151807 1490589 483458..483583 1 NC_002940.2 hypothetical protein 483583 1490589 HD0622 Haemophilus ducreyi 35000HP hypothetical protein NP_873160.1 483458 D 233412 CDS NP_873161.1 33151808 1490590 483603..485747 1 NC_002940.2 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 485747 priA 1490590 priA Haemophilus ducreyi 35000HP primosome assembly protein PriA NP_873161.1 483603 D 233412 CDS NP_873162.1 33151809 1490591 complement(485783..486907) 1 NC_002940.2 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 486907 alr 1490591 alr Haemophilus ducreyi 35000HP alanine racemase NP_873162.1 485783 R 233412 CDS NP_873163.1 33151810 1490592 486894..486986 1 NC_002940.2 hypothetical protein 486986 1490592 HD0625 Haemophilus ducreyi 35000HP hypothetical protein NP_873163.1 486894 D 233412 CDS NP_873164.1 33151811 1490593 487021..488967 1 NC_002940.2 exodeoxyribonuclease V subunit alpha 488967 recD 1490593 recD Haemophilus ducreyi 35000HP exodeoxyribonuclease V subunit alpha NP_873164.1 487021 D 233412 CDS NP_873165.1 33151812 1490594 488961..489056 1 NC_002940.2 hypothetical protein 489056 1490594 HD0627 Haemophilus ducreyi 35000HP hypothetical protein NP_873165.1 488961 D 233412 CDS NP_873166.1 33151813 1490600 494797..496035 1 NC_002940.2 hypothetical protein 496035 1490600 HD0629 Haemophilus ducreyi 35000HP hypothetical protein NP_873166.1 494797 D 233412 CDS NP_873167.1 33151814 1490601 496188..497012 1 NC_002940.2 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 497012 dapD 1490601 dapD Haemophilus ducreyi 35000HP 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase NP_873167.1 496188 D 233412 CDS NP_873168.1 33151815 1490602 497057..497401 1 NC_002940.2 arsenate reductase 497401 arsC 1490602 arsC Haemophilus ducreyi 35000HP arsenate reductase NP_873168.1 497057 D 233412 CDS NP_873169.1 33151816 1490603 497410..497844 1 NC_002940.2 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 497844 aroQ 1490603 aroQ Haemophilus ducreyi 35000HP 3-dehydroquinate dehydratase NP_873169.1 497410 D 233412 CDS NP_873170.1 33151817 1490604 498075..498533 1 NC_002940.2 biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP) 498533 accB 1490604 accB Haemophilus ducreyi 35000HP biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP) NP_873170.1 498075 D 233412 CDS NP_873171.1 33151818 1490605 498720..500063 1 NC_002940.2 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 500063 accC 1490605 accC Haemophilus ducreyi 35000HP acetyl-CoA carboxylase biotin carboxylase subunit NP_873171.1 498720 D 233412 CDS NP_873172.1 33151819 1490606 complement(500108..501208) 1 NC_002940.2 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; MobB is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobA/MobB 501208 mobAB 1490606 mobAB Haemophilus ducreyi 35000HP bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobA/MobB NP_873172.1 500108 R 233412 CDS NP_873173.1 33151820 1490607 501292..501561 1 NC_002940.2 hypothetical protein 501561 1490607 HD0637 Haemophilus ducreyi 35000HP hypothetical protein NP_873173.1 501292 D 233412 CDS NP_873174.1 33151821 1490608 501611..502249 1 NC_002940.2 thiol:disulfide interchange protein 502249 dsbA 1490608 dsbA Haemophilus ducreyi 35000HP thiol:disulfide interchange protein NP_873174.1 501611 D 233412 CDS NP_873175.1 33151822 1490609 complement(502293..503138) 1 NC_002940.2 cell division protein 503138 1490609 HD0639 Haemophilus ducreyi 35000HP cell division protein NP_873175.1 502293 R 233412 CDS NP_873176.1 33151823 1490610 complement(503263..504018) 1 NC_002940.2 SAM-dependent methyltransferase 504018 1490610 HD0640 Haemophilus ducreyi 35000HP SAM-dependent methyltransferase NP_873176.1 503263 R 233412 CDS NP_873177.1 33151824 1490611 complement(504028..504708) 1 NC_002940.2 D,D-carboxypeptidase-related protein 504708 1490611 HD0641 Haemophilus ducreyi 35000HP D,D-carboxypeptidase-related protein NP_873177.1 504028 R 233412 CDS NP_873178.1 33151825 1490612 complement(504718..505848) 1 NC_002940.2 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 505848 dapE 1490612 dapE Haemophilus ducreyi 35000HP succinyl-diaminopimelate desuccinylase NP_873178.1 504718 R 233412 CDS NP_873179.1 33151826 1490613 complement(505932..506285) 1 NC_002940.2 hypothetical protein 506285 1490613 HD0643 Haemophilus ducreyi 35000HP hypothetical protein NP_873179.1 505932 R 233412 CDS NP_873180.1 33151827 1490614 complement(506294..507139) 1 NC_002940.2 dihydropteroate synthase 507139 folP 1490614 folP Haemophilus ducreyi 35000HP dihydropteroate synthase NP_873180.1 506294 R 233412 CDS NP_873181.1 33151828 1490615 complement(507141..508103) 1 NC_002940.2 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 508103 rluC 1490615 rluC Haemophilus ducreyi 35000HP 23S rRNA pseudouridylate synthase C NP_873181.1 507141 R 233412 CDS NP_873182.1 33151829 1490616 508270..510765 1 NC_002940.2 hypothetical protein 510765 1490616 HD0646 Haemophilus ducreyi 35000HP hypothetical protein NP_873182.1 508270 D 233412 CDS NP_873183.1 33151830 1490617 510876..511844 1 NC_002940.2 hypothetical protein 511844 1490617 HD0647 Haemophilus ducreyi 35000HP hypothetical protein NP_873183.1 510876 D 233412 CDS NP_873184.1 33151831 1490618 complement(511908..513107) 1 NC_002940.2 tryptophan-specific transport protein 513107 tnaB 1490618 tnaB Haemophilus ducreyi 35000HP tryptophan-specific transport protein NP_873184.1 511908 R 233412 CDS NP_873185.1 33151832 1490619 complement(513166..514059) 1 NC_002940.2 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 514059 psd 1490619 psd Haemophilus ducreyi 35000HP phosphatidylserine decarboxylase NP_873185.1 513166 R 233412 CDS NP_873186.1 33151833 1490620 complement(514212..514571) 1 NC_002940.2 hypothetical protein 514571 1490620 HD0650 Haemophilus ducreyi 35000HP hypothetical protein NP_873186.1 514212 R 233412 CDS NP_873187.1 33151834 1490621 514878..516107 1 NC_002940.2 opacity associated protein A 516107 oapA 1490621 oapA Haemophilus ducreyi 35000HP opacity associated protein A NP_873187.1 514878 D 233412 CDS NP_873188.1 33151835 1490622 516198..516614 1 NC_002940.2 opacity associated protein B 516614 oapB 1490622 oapB Haemophilus ducreyi 35000HP opacity associated protein B NP_873188.1 516198 D 233412 CDS NP_873189.1 33151836 1490623 516830..517735 1 NC_002940.2 ADP-heptose--lipooligosaccharide heptosyltransferase II 517735 waaF 1490623 waaF Haemophilus ducreyi 35000HP ADP-heptose--lipooligosaccharide heptosyltransferase II NP_873189.1 516830 D 233412 CDS NP_873190.1 33151837 1490624 complement(517686..517901) 1 NC_002940.2 hypothetical protein 517901 1490624 HD0654 Haemophilus ducreyi 35000HP hypothetical protein NP_873190.1 517686 R 233412 CDS NP_873191.1 33151838 1490625 517884..518258 1 NC_002940.2 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 518258 rpsL 1490625 rpsL Haemophilus ducreyi 35000HP 30S ribosomal protein S12 NP_873191.1 517884 D 233412 CDS NP_873192.1 33151839 1490626 518395..518865 1 NC_002940.2 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 518865 rpsG 1490626 rpsG Haemophilus ducreyi 35000HP 30S ribosomal protein S7 NP_873192.1 518395 D 233412 CDS NP_873193.1 33151840 1490627 518964..521069 1 NC_002940.2 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 521069 fusA 1490627 fusA Haemophilus ducreyi 35000HP elongation factor G NP_873193.1 518964 D 233412 CDS NP_873194.1 33151841 1490628 521131..522315 1 NC_002940.2 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 522315 tuf 1490628 tuf Haemophilus ducreyi 35000HP elongation factor Tu NP_873194.1 521131 D 233412 CDS NP_873195.1 33151842 1490629 complement(522487..523302) 1 NC_002940.2 catalyzes the O-acetylation of serine; serine acetyltransferase 523302 cysE 1490629 cysE Haemophilus ducreyi 35000HP serine acetyltransferase NP_873195.1 522487 R 233412 CDS NP_873196.1 33151843 1490630 complement(523314..524324) 1 NC_002940.2 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 524324 gpsA 1490630 gpsA Haemophilus ducreyi 35000HP NAD(P)H-dependent glycerol-3-phosphate dehydrogenase NP_873196.1 523314 R 233412 CDS NP_873197.1 33151844 1490631 complement(524451..524969) 1 NC_002940.2 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 524969 secB 1490631 secB Haemophilus ducreyi 35000HP preprotein translocase subunit SecB NP_873197.1 524451 R 233412 CDS NP_873198.1 33151845 1490632 complement(524989..525435) 1 NC_002940.2 rhodanese-related sulfurtransferase 525435 1490632 HD0662 Haemophilus ducreyi 35000HP rhodanese-related sulfurtransferase NP_873198.1 524989 R 233412 CDS NP_873199.1 33151846 1490633 complement(525554..526855) 1 NC_002940.2 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 526855 tig 1490633 tig Haemophilus ducreyi 35000HP trigger factor NP_873199.1 525554 R 233412 CDS NP_873200.1 33151847 1490634 complement(526948..527049) 1 NC_002940.2 hypothetical protein 527049 1490634 HD0664 Haemophilus ducreyi 35000HP hypothetical protein NP_873200.1 526948 R 233412 CDS NP_873201.1 33151848 1490635 complement(527074..527517) 1 NC_002940.2 LysM domain/BON superfamily protein 527517 1490635 HD0665 Haemophilus ducreyi 35000HP LysM domain/BON superfamily protein NP_873201.1 527074 R 233412 CDS NP_873202.1 33151849 1490636 527767..528228 1 NC_002940.2 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 528228 holC 1490636 holC Haemophilus ducreyi 35000HP DNA polymerase III subunit chi NP_873202.1 527767 D 233412 CDS NP_873203.1 33151850 1490637 528291..529163 1 NC_002940.2 hypothetical protein 529163 1490637 HD0668 Haemophilus ducreyi 35000HP hypothetical protein NP_873203.1 528291 D 233412 CDS NP_873204.1 33151851 1490638 529205..532090 1 NC_002940.2 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 532090 valS 1490638 valS Haemophilus ducreyi 35000HP valyl-tRNA synthetase NP_873204.1 529205 D 233412 CDS NP_873205.1 33151852 1490639 complement(532200..533627) 1 NC_002940.2 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 533627 panF 1490639 panF Haemophilus ducreyi 35000HP sodium/panthothenate symporter NP_873205.1 532200 R 233412 CDS NP_873206.1 33151853 1490640 complement(533620..533868) 1 NC_002940.2 hypothetical protein 533868 1490640 HD0673 Haemophilus ducreyi 35000HP hypothetical protein NP_873206.1 533620 R 233412 CDS NP_873207.1 33151854 1490641 complement(533928..534245) 1 NC_002940.2 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 534245 metJ 1490641 metJ Haemophilus ducreyi 35000HP transcriptional repressor protein MetJ NP_873207.1 533928 R 233412 CDS NP_873208.1 33151855 1490642 534438..535181 1 NC_002940.2 VacJ lipoprotein 535181 vacJ 1490642 vacJ Haemophilus ducreyi 35000HP VacJ lipoprotein NP_873208.1 534438 D 233412 CDS NP_873209.1 33151856 1490643 535390..537360 1 NC_002940.2 site-specific recombinase 537360 gcr 1490643 gcr Haemophilus ducreyi 35000HP site-specific recombinase NP_873209.1 535390 D 233412 CDS NP_873210.1 33151857 1490644 complement(537432..538109) 1 NC_002940.2 hypothetical protein 538109 1490644 HD0680 Haemophilus ducreyi 35000HP hypothetical protein NP_873210.1 537432 R 233412 CDS NP_873211.1 33151858 1490645 complement(538081..538182) 1 NC_002940.2 hypothetical protein 538182 1490645 HD0681 Haemophilus ducreyi 35000HP hypothetical protein NP_873211.1 538081 R 233412 CDS NP_873212.1 33151859 1490646 complement(538216..538950) 1 NC_002940.2 hypothetical protein 538950 1490646 HD0682 Haemophilus ducreyi 35000HP hypothetical protein NP_873212.1 538216 R 233412 CDS NP_873213.1 33151860 1490647 539049..539957 1 NC_002940.2 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 539957 menA 1490647 menA Haemophilus ducreyi 35000HP 1,4-dihydroxy-2-naphthoate octaprenyltransferase NP_873213.1 539049 D 233412 CDS NP_873214.1 33151861 1490648 complement(540037..540381) 1 NC_002940.2 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 540381 1490648 HD0684 Haemophilus ducreyi 35000HP iron-sulfur cluster insertion protein ErpA NP_873214.1 540037 R 233412 CDS NP_873215.1 33151862 1490649 540594..541283 1 NC_002940.2 cytidine 5'monophosphate N-acetylneuraminic acid synthetase; acylneuraminate cytidylyltransferase 541283 neuA 1490649 neuA Haemophilus ducreyi 35000HP acylneuraminate cytidylyltransferase NP_873215.1 540594 D 233412 CDS NP_873216.1 33151863 1490650 541332..542219 1 NC_002940.2 lipooligosaccharide sialyltransferase 542219 lst 1490650 lst Haemophilus ducreyi 35000HP lipooligosaccharide sialyltransferase NP_873216.1 541332 D 233412 CDS NP_873217.1 33151864 1490651 542311..543351 1 NC_002940.2 dTDP-D-glucose 4,6-dehydratase 543351 rmlB 1490651 rmlB Haemophilus ducreyi 35000HP dTDP-D-glucose 4,6-dehydratase NP_873217.1 542311 D 233412 CDS NP_873218.1 33151865 1490652 543373..544260 1 NC_002940.2 dTDP-glucose synthase; glucose-1-phosphate thymidyltransferase; dTDP-glucose phosphorylase 544260 rmlA 1490652 rmlA Haemophilus ducreyi 35000HP dTDP-glucose phosphorylase NP_873218.1 543373 D 233412 CDS NP_873219.1 33151866 1490653 544413..544628 1 NC_002940.2 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 544628 rpsU 1490653 rpsU Haemophilus ducreyi 35000HP 30S ribosomal protein S21 NP_873219.1 544413 D 233412 CDS NP_873220.1 33151867 1490654 544816..546555 1 NC_002940.2 synthesizes RNA primers at the replication forks; DNA primase 546555 dnaG 1490654 dnaG Haemophilus ducreyi 35000HP DNA primase NP_873220.1 544816 D 233412 CDS NP_873221.1 33151868 1490655 546696..548537 1 NC_002940.2 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 548537 rpoD 1490655 rpoD Haemophilus ducreyi 35000HP RNA polymerase sigma factor RpoD NP_873221.1 546696 D 233412 CDS NP_873222.1 33151869 1490656 complement(548683..549873) 1 NC_002940.2 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 549873 tyrS 1490656 tyrS Haemophilus ducreyi 35000HP tyrosyl-tRNA synthetase NP_873222.1 548683 R 233412 CDS NP_873223.1 33151870 1490657 complement(550101..550223) 1 NC_002940.2 hypothetical protein 550223 1490657 HD0694 Haemophilus ducreyi 35000HP hypothetical protein NP_873223.1 550101 R 233412 CDS NP_873224.1 33151871 1490658 complement(550216..552573) 1 NC_002940.2 ribonuclease r, virulence associated protein VacB-like protein 552573 vacB 1490658 vacB Haemophilus ducreyi 35000HP ribonuclease r, virulence associated protein VacB-like protein NP_873224.1 550216 R 233412 CDS NP_873225.1 33151872 1490659 complement(552635..553153) 1 NC_002940.2 thioredoxin-like protein 553153 1490659 HD0697 Haemophilus ducreyi 35000HP thioredoxin-like protein NP_873225.1 552635 R 233412 CDS NP_873226.1 33151873 1490660 complement(553155..553781) 1 NC_002940.2 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 553781 1490660 HD0698 Haemophilus ducreyi 35000HP DNA-binding transcriptional repressor FabR NP_873226.1 553155 R 233412 CDS NP_873227.1 33151874 1490661 complement(553774..554667) 1 NC_002940.2 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 554667 oxyR 1490661 oxyR Haemophilus ducreyi 35000HP DNA-binding transcriptional regulator OxyR NP_873227.1 553774 R 233412 CDS NP_873228.1 33151875 1490662 554795..555529 1 NC_002940.2 peroxiredoxin/glutaredoxin family protein 555529 1490662 HD0700 Haemophilus ducreyi 35000HP peroxiredoxin/glutaredoxin family protein NP_873228.1 554795 D 233412 CDS NP_873229.1 33151876 1490663 complement(555639..556643) 1 NC_002940.2 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 556643 fbp 1490663 fbp Haemophilus ducreyi 35000HP fructose-1,6-bisphosphatase NP_873229.1 555639 R 233412 CDS NP_873230.1 33151877 1490664 556767..558146 1 NC_002940.2 murein peptide ligase; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamayl- meso-diaminopimelate ligase 558146 mpl 1490664 mpl Haemophilus ducreyi 35000HP UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamayl- meso-diaminopimelate ligase NP_873230.1 556767 D 233412 CDS NP_873231.1 33151878 1490665 complement(558164..558355) 1 NC_002940.2 hypothetical protein 558355 1490665 HD0704 Haemophilus ducreyi 35000HP hypothetical protein NP_873231.1 558164 R 233412 CDS NP_873232.1 33151879 1490666 558367..559350 1 NC_002940.2 octaprenyl-diphosphate synthase; octaprenyl pyrophosphate synthetase 559350 ispB 1490666 ispB Haemophilus ducreyi 35000HP octaprenyl pyrophosphate synthetase NP_873232.1 558367 D 233412 CDS NP_873233.1 33151880 1490667 559387..560136 1 NC_002940.2 hypothetical protein 560136 1490667 HD0706 Haemophilus ducreyi 35000HP hypothetical protein NP_873233.1 559387 D 233412 CDS NP_873234.1 33151881 1490668 560270..561205 1 NC_002940.2 ACP S-malonyltransferase 561205 fabD 1490668 fabD Haemophilus ducreyi 35000HP ACP S-malonyltransferase NP_873234.1 560270 D 233412 CDS NP_873235.1 33151882 1490669 561260..561916 1 NC_002940.2 3-oxoacyl-ACP reductase 561916 fabG 1490669 fabG Haemophilus ducreyi 35000HP 3-oxoacyl-ACP reductase NP_873235.1 561260 D 233412 CDS NP_873236.1 33151883 1490670 562116..563420 1 NC_002940.2 branched-chain amino acid carrier protein 563420 brnQ 1490670 brnQ Haemophilus ducreyi 35000HP branched-chain amino acid carrier protein NP_873236.1 562116 D 233412 CDS NP_873237.1 33151884 1490671 563452..564276 1 NC_002940.2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 564276 mutM 1490671 mutM Haemophilus ducreyi 35000HP formamidopyrimidine-DNA glycosylase NP_873237.1 563452 D 233412 CDS NP_873238.1 33151885 1490672 complement(564342..564704) 1 NC_002940.2 hypothetical protein 564704 1490672 HD0713 Haemophilus ducreyi 35000HP hypothetical protein NP_873238.1 564342 R 233412 CDS NP_873239.1 33151886 1490673 complement(564771..565520) 1 NC_002940.2 Sec-independent protein secretion pathway component TatC 565520 tatC 1490673 tatC Haemophilus ducreyi 35000HP Sec-independent protein secretion pathway component TatC NP_873239.1 564771 R 233412 CDS NP_873240.1 33151887 1490674 complement(565510..565998) 1 NC_002940.2 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 565998 tatB 1490674 tatB Haemophilus ducreyi 35000HP sec-independent translocase NP_873240.1 565510 R 233412 CDS NP_873241.1 33151888 1490675 complement(566002..566226) 1 NC_002940.2 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 566226 tatA 1490675 tatA Haemophilus ducreyi 35000HP twin arginine translocase protein A NP_873241.1 566002 R 233412 CDS NP_873242.1 33151889 1490676 complement(566355..567983) 1 NC_002940.2 ubiquinone biosynthesis protein 567983 ubiB 1490676 ubiB Haemophilus ducreyi 35000HP ubiquinone biosynthesis protein NP_873242.1 566355 R 233412 CDS NP_873243.1 33151890 1490677 complement(567980..568618) 1 NC_002940.2 hypothetical protein 568618 1490677 HD0718 Haemophilus ducreyi 35000HP hypothetical protein NP_873243.1 567980 R 233412 CDS NP_873244.1 33151891 1490678 complement(568650..569429) 1 NC_002940.2 ubiquinone/menaquinone biosynthesis methyltransferase 569429 ubiE 1490678 ubiE Haemophilus ducreyi 35000HP ubiquinone/menaquinone biosynthesis methyltransferase NP_873244.1 568650 R 233412 CDS NP_873245.1 33151892 1490679 complement(569440..569541) 1 NC_002940.2 hypothetical protein 569541 1490679 HD0720 Haemophilus ducreyi 35000HP hypothetical protein NP_873245.1 569440 R 233412 CDS NP_873246.1 33151893 1490680 569718..570671 1 NC_002940.2 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 570671 corA 1490680 corA Haemophilus ducreyi 35000HP magnesium/nickel/cobalt transporter CorA NP_873246.1 569718 D 233412 CDS NP_873247.1 33151894 1490682 complement(570808..570963) 1 NC_002940.2 hypothetical protein 570963 1490682 HD0722 Haemophilus ducreyi 35000HP hypothetical protein NP_873247.1 570808 R 233412 CDS NP_873248.1 33151895 1490683 complement(570980..572089) 1 NC_002940.2 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 572089 trmA 1490683 trmA Haemophilus ducreyi 35000HP tRNA (uracil-5-)-methyltransferase NP_873248.1 570980 R 233412 CDS NP_873249.1 33151896 1490684 complement(572209..572541) 1 NC_002940.2 hypothetical protein 572541 1490684 HD0725 Haemophilus ducreyi 35000HP hypothetical protein NP_873249.1 572209 R 233412 CDS NP_873250.1 33151897 1490685 complement(572758..574293) 1 NC_002940.2 L-2,4-diaminobutyrate decarboxylase 574293 ddc 1490685 ddc Haemophilus ducreyi 35000HP L-2,4-diaminobutyrate decarboxylase NP_873250.1 572758 R 233412 CDS NP_873251.1 33151898 1490686 574330..574449 1 NC_002940.2 hypothetical protein 574449 1490686 HD0727 Haemophilus ducreyi 35000HP hypothetical protein NP_873251.1 574330 D 233412 CDS NP_873252.1 33151899 1490687 complement(574450..575814) 1 NC_002940.2 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase 575814 dat 1490687 dat Haemophilus ducreyi 35000HP diaminobutyrate--2-oxoglutarate aminotransferase NP_873252.1 574450 R 233412 CDS NP_873253.1 33151900 1490688 complement(576143..576313) 1 NC_002940.2 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 576313 rpmG 1490688 rpmG Haemophilus ducreyi 35000HP 50S ribosomal protein L33 NP_873253.1 576143 R 233412 CDS NP_873254.1 33151901 1490689 complement(576325..576561) 1 NC_002940.2 required for 70S ribosome assembly; 50S ribosomal protein L28 576561 rpmB 1490689 rpmB Haemophilus ducreyi 35000HP 50S ribosomal protein L28 NP_873254.1 576325 R 233412 CDS NP_873255.1 33151902 1490690 complement(576722..577393) 1 NC_002940.2 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 577393 radC 1490690 radC Haemophilus ducreyi 35000HP DNA repair protein RadC NP_873255.1 576722 R 233412 CDS NP_873256.1 33151903 1490691 577607..578851 1 NC_002940.2 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 578851 dfp 1490691 dfp Haemophilus ducreyi 35000HP bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase NP_873256.1 577607 D 233412 CDS NP_873257.1 33151904 1490692 578835..579293 1 NC_002940.2 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 579293 dut 1490692 dut Haemophilus ducreyi 35000HP deoxyuridine 5'-triphosphate nucleotidohydrolase NP_873257.1 578835 D 233412 CDS NP_873258.1 33151905 1490693 579397..580005 1 NC_002940.2 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 580005 slmA 1490693 slmA Haemophilus ducreyi 35000HP nucleoid occlusion protein NP_873258.1 579397 D 233412 CDS NP_873259.1 33151906 1490694 580014..580232 1 NC_002940.2 hypothetical protein 580232 1490694 HD0737 Haemophilus ducreyi 35000HP hypothetical protein NP_873259.1 580014 D 233412 CDS NP_873260.1 33151907 1490695 580317..581000 1 NC_002940.2 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 581000 crp 1490695 crp Haemophilus ducreyi 35000HP cAMP-regulatory protein NP_873260.1 580317 D 233412 CDS NP_873261.1 33151908 1490696 complement(581070..582419) 1 NC_002940.2 GTP-binding protein HflX 582419 hflX 1490696 hflX Haemophilus ducreyi 35000HP GTP-binding protein HflX NP_873261.1 581070 R 233412 CDS NP_873262.1 33151909 1490697 complement(582457..582762) 1 NC_002940.2 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 582762 hfq 1490697 hfq Haemophilus ducreyi 35000HP RNA-binding protein Hfq NP_873262.1 582457 R 233412 CDS NP_873263.1 33151910 1490698 complement(582837..583778) 1 NC_002940.2 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 583778 miaA 1490698 miaA Haemophilus ducreyi 35000HP tRNA delta(2)-isopentenylpyrophosphate transferase NP_873263.1 582837 R 233412 CDS NP_873264.1 33151911 1490699 complement(583842..585638) 1 NC_002940.2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 585638 mutL 1490699 mutL Haemophilus ducreyi 35000HP DNA mismatch repair protein NP_873264.1 583842 R 233412 CDS NP_873265.1 33151912 1490700 585746..586573 1 NC_002940.2 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 586573 rbn 1490700 rbn Haemophilus ducreyi 35000HP ribonuclease BN NP_873265.1 585746 D 233412 CDS NP_873266.1 33151913 1490701 586563..587009 1 NC_002940.2 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 587009 dtd 1490701 dtd Haemophilus ducreyi 35000HP D-tyrosyl-tRNA(Tyr) deacylase NP_873266.1 586563 D 233412 CDS NP_873267.1 33151914 1490702 complement(587075..587614) 1 NC_002940.2 possible xylanase A; endo-1,4-beta-xylanase A 587614 1490702 HD0746 Haemophilus ducreyi 35000HP endo-1,4-beta-xylanase A NP_873267.1 587075 R 233412 CDS NP_873268.1 33151915 1490703 complement(587760..588944) 1 NC_002940.2 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 588944 nhaA 1490703 nhaA Haemophilus ducreyi 35000HP pH-dependent sodium/proton antiporter NP_873268.1 587760 R 233412 CDS NP_873269.1 33151916 1490704 589116..589856 1 NC_002940.2 hypothetical protein 589856 1490704 HD0748 Haemophilus ducreyi 35000HP hypothetical protein NP_873269.1 589116 D 233412 CDS NP_873270.1 33151917 1490705 590081..590908 1 NC_002940.2 cyclic 3',5'-adenosine monophosphate phosphodiesterase 590908 icc 1490705 icc Haemophilus ducreyi 35000HP cyclic 3',5'-adenosine monophosphate phosphodiesterase NP_873270.1 590081 D 233412 CDS NP_873271.1 33151918 1490706 591128..592558 1 NC_002940.2 glutamine synthetase; glutamate--ammonia ligase 592558 glnA 1490706 glnA Haemophilus ducreyi 35000HP glutamate--ammonia ligase NP_873271.1 591128 D 233412 CDS NP_873272.1 33151919 1490707 complement(592591..592689) 1 NC_002940.2 hypothetical protein 592689 1490707 HD0751 Haemophilus ducreyi 35000HP hypothetical protein NP_873272.1 592591 R 233412 CDS NP_873273.1 33151920 1490708 complement(592839..593210) 1 NC_002940.2 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 593210 rnpA 1490708 rnpA Haemophilus ducreyi 35000HP ribonuclease P NP_873273.1 592839 R 233412 CDS NP_873274.1 33151921 1490709 complement(593243..593377) 1 NC_002940.2 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 593377 rpmH 1490709 rpmH Haemophilus ducreyi 35000HP 50S ribosomal protein L34 NP_873274.1 593243 R 233412 CDS NP_873275.1 33151922 1490710 complement(593415..593516) 1 NC_002940.2 hypothetical protein 593516 1490710 HD0754 Haemophilus ducreyi 35000HP hypothetical protein NP_873275.1 593415 R 233412 CDS NP_873276.1 33151923 1490711 complement(593671..594789) 1 NC_002940.2 lipoprotein 594789 nlpD 1490711 nlpD Haemophilus ducreyi 35000HP lipoprotein NP_873276.1 593671 R 233412 CDS NP_873277.1 33151924 1490712 complement(594874..595452) 1 NC_002940.2 lipoprotein 595452 1490712 HD0756 Haemophilus ducreyi 35000HP lipoprotein NP_873277.1 594874 R 233412 CDS NP_873278.1 33151925 1490713 complement(595464..596048) 1 NC_002940.2 hypothetical protein 596048 1490713 HD0757 Haemophilus ducreyi 35000HP hypothetical protein NP_873278.1 595464 R 233412 CDS NP_873279.1 33151926 1490714 complement(596049..596810) 1 NC_002940.2 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 596810 surE 1490714 surE Haemophilus ducreyi 35000HP stationary phase survival protein SurE NP_873279.1 596049 R 233412 CDS NP_873280.1 33151927 1490716 598103..598873 1 NC_002940.2 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 598873 tpiA 1490716 tpiA Haemophilus ducreyi 35000HP triosephosphate isomerase NP_873280.1 598103 D 233412 CDS NP_873281.1 33151928 1490717 complement(598978..600189) 1 NC_002940.2 mannose-6-phosphate isomerase 600189 manA 1490717 manA Haemophilus ducreyi 35000HP mannose-6-phosphate isomerase NP_873281.1 598978 R 233412 CDS NP_873282.1 33151929 1490718 complement(600349..601200) 1 NC_002940.2 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 601200 manZ 1490718 manZ Haemophilus ducreyi 35000HP PTS system mannose-specific transporter subunit IID NP_873282.1 600349 R 233412 CDS NP_873283.1 33151930 1490719 complement(601200..602000) 1 NC_002940.2 mannose-specific phosphotransferase system IIC component 602000 manY 1490719 manY Haemophilus ducreyi 35000HP mannose-specific phosphotransferase system IIC component NP_873283.1 601200 R 233412 CDS NP_873284.1 33151931 1490720 complement(602010..602990) 1 NC_002940.2 mannose-specific phosphotransferase IIAB component 602990 manX 1490720 manX Haemophilus ducreyi 35000HP mannose-specific phosphotransferase IIAB component NP_873284.1 602010 R 233412 CDS NP_873285.1 33151932 1490721 603357..604130 1 NC_002940.2 serum resistance protein DrsA 604130 dsrA 1490721 dsrA Haemophilus ducreyi 35000HP serum resistance protein DrsA NP_873285.1 603357 D 233412 CDS NP_873286.1 33151933 1490722 complement(604278..605600) 1 NC_002940.2 hypothetical protein 605600 1490722 HD0770 Haemophilus ducreyi 35000HP hypothetical protein NP_873286.1 604278 R 233412 CDS NP_873287.1 33151934 1490723 605719..606243 1 NC_002940.2 hypothetical protein 606243 1490723 HD0771 Haemophilus ducreyi 35000HP hypothetical protein NP_873287.1 605719 D 233412 CDS NP_873288.1 33151935 1490724 606262..606432 1 NC_002940.2 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 606432 rpmF 1490724 rpmF Haemophilus ducreyi 35000HP 50S ribosomal protein L32 NP_873288.1 606262 D 233412 CDS NP_873289.1 33151936 1490725 606454..607485 1 NC_002940.2 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 607485 plsX 1490725 plsX Haemophilus ducreyi 35000HP glycerol-3-phosphate acyltransferase PlsX NP_873289.1 606454 D 233412 CDS NP_873290.1 33151937 1490726 607497..608447 1 NC_002940.2 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 608447 fabH 1490726 fabH Haemophilus ducreyi 35000HP 3-oxoacyl-ACP synthase NP_873290.1 607497 D 233412 CDS NP_873291.1 33151938 1490727 608457..609206 1 NC_002940.2 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 609206 trmB 1490727 trmB Haemophilus ducreyi 35000HP tRNA (guanine-N(7)-)-methyltransferase NP_873291.1 608457 D 233412 CDS NP_873292.1 33151939 1490728 609287..609628 1 NC_002940.2 hypothetical protein 609628 1490728 HD0776 Haemophilus ducreyi 35000HP hypothetical protein NP_873292.1 609287 D 233412 CDS NP_873293.1 33151940 1490729 609767..610300 1 NC_002940.2 hypothetical protein 610300 1490729 HD0777 Haemophilus ducreyi 35000HP hypothetical protein NP_873293.1 609767 D 233412 CDS NP_873294.1 33151941 1490730 610300..610593 1 NC_002940.2 hypothetical protein 610593 1490730 HD0778 Haemophilus ducreyi 35000HP hypothetical protein NP_873294.1 610300 D 233412 CDS NP_873295.1 33151942 1490732 complement(612267..612590) 1 NC_002940.2 alkylphosphonate uptake protein 612590 phnA 1490732 phnA Haemophilus ducreyi 35000HP alkylphosphonate uptake protein NP_873295.1 612267 R 233412 CDS NP_873296.1 33151943 1490733 complement(612707..614014) 1 NC_002940.2 oxaloacetate decarboxylase subunit beta 614014 oadB 1490733 oadB Haemophilus ducreyi 35000HP oxaloacetate decarboxylase subunit beta NP_873296.1 612707 R 233412 CDS NP_873297.1 33151944 1490734 complement(614026..615831) 1 NC_002940.2 catalyzes the formation of pyruvate from oxaloacetate; oxaloacetate decarboxylase 615831 oadA 1490734 oadA Haemophilus ducreyi 35000HP oxaloacetate decarboxylase NP_873297.1 614026 R 233412 CDS NP_873298.1 33151945 1490735 complement(615841..616098) 1 NC_002940.2 catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide; oxaloacetate decarboxylase subunit gamma 616098 oadG 1490735 oadG Haemophilus ducreyi 35000HP oxaloacetate decarboxylase subunit gamma NP_873298.1 615841 R 233412 CDS NP_873299.1 33151946 1490742 622394..623104 1 NC_002940.2 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 623104 yfgE 1490742 yfgE Haemophilus ducreyi 35000HP DNA replication initiation factor NP_873299.1 622394 D 233412 CDS NP_873300.1 33151947 1490743 623243..623875 1 NC_002940.2 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 623875 ccmA 1490743 ccmA Haemophilus ducreyi 35000HP cytochrome c biogenesis protein CcmA NP_873300.1 623243 D 233412 CDS NP_873301.1 33151948 1490744 623937..624599 1 NC_002940.2 heme exporter protein B; cytochrome c-type biogenesis protein 624599 ccmB 1490744 ccmB Haemophilus ducreyi 35000HP cytochrome c-type biogenesis protein NP_873301.1 623937 D 233412 CDS NP_873302.1 33151949 1490745 624661..625398 1 NC_002940.2 heme exporter protein C; cytochrome c-type biogenesis protein 625398 ccmC 1490745 ccmC Haemophilus ducreyi 35000HP cytochrome c-type biogenesis protein NP_873302.1 624661 D 233412 CDS NP_873303.1 33151950 1490746 625421..625624 1 NC_002940.2 heme exporter protein D; cytochrome c maturation protein D 625624 ccmD 1490746 ccmD Haemophilus ducreyi 35000HP cytochrome c maturation protein D NP_873303.1 625421 D 233412 CDS NP_873304.1 33151951 1490747 625806..626351 1 NC_002940.2 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 626351 ccmE 1490747 ccmE Haemophilus ducreyi 35000HP cytochrome c-type biogenesis protein CcmE NP_873304.1 625806 D 233412 CDS NP_873305.1 33151952 1490748 626351..628309 1 NC_002940.2 cytochrome c-type biogenesis protein 628309 ccmF 1490748 ccmF Haemophilus ducreyi 35000HP cytochrome c-type biogenesis protein NP_873305.1 626351 D 233412 CDS NP_873306.1 33151953 1490749 628456..629472 1 NC_002940.2 transport system permease 629472 1490749 HD0793 Haemophilus ducreyi 35000HP transport system permease NP_873306.1 628456 D 233412 CDS NP_873307.1 33151954 1490750 629444..629698 1 NC_002940.2 hypothetical protein 629698 1490750 HD0794 Haemophilus ducreyi 35000HP hypothetical protein NP_873307.1 629444 D 233412 CDS NP_873308.1 33151955 1490751 629673..630878 1 NC_002940.2 thiosulfate sulfur transferase 630878 1490751 HD0795 Haemophilus ducreyi 35000HP thiosulfate sulfur transferase NP_873308.1 629673 D 233412 CDS NP_873309.1 33151956 1490755 632928..634346 1 NC_002940.2 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 634346 1490755 HD0798 Haemophilus ducreyi 35000HP transglycosylase NP_873309.1 632928 D 233412 CDS NP_873310.1 33151957 1490756 634410..634547 1 NC_002940.2 hypothetical protein 634547 1490756 HD0799 Haemophilus ducreyi 35000HP hypothetical protein NP_873310.1 634410 D 233412 CDS NP_873311.1 33151958 1490757 complement(634617..635207) 1 NC_002940.2 hypothetical protein 635207 1490757 HD0800 Haemophilus ducreyi 35000HP hypothetical protein NP_873311.1 634617 R 233412 CDS NP_873312.1 33151959 1490758 complement(635226..635807) 1 NC_002940.2 phosphoheptose isomerase 635807 1490758 HD0801 Haemophilus ducreyi 35000HP phosphoheptose isomerase NP_873312.1 635226 R 233412 CDS NP_873313.1 33151960 1490759 complement(635818..636198) 1 NC_002940.2 hypothetical protein 636198 1490759 HD0802 Haemophilus ducreyi 35000HP hypothetical protein NP_873313.1 635818 R 233412 CDS NP_873314.1 33151961 1490760 complement(636173..637924) 1 NC_002940.2 lipoprotein C 637924 lppC 1490760 lppC Haemophilus ducreyi 35000HP lipoprotein C NP_873314.1 636173 R 233412 CDS NP_873315.1 33151962 1490761 637997..638851 1 NC_002940.2 hypothetical protein 638851 1490761 HD0804 Haemophilus ducreyi 35000HP hypothetical protein NP_873315.1 637997 D 233412 CDS NP_873316.1 33151963 1490762 complement(638903..639706) 1 NC_002940.2 hypothetical protein 639706 1490762 HD0805 Haemophilus ducreyi 35000HP hypothetical protein NP_873316.1 638903 R 233412 CDS NP_873317.1 33151964 1490763 complement(639852..640421) 1 NC_002940.2 hypothetical protein 640421 1490763 HD0806 Haemophilus ducreyi 35000HP hypothetical protein NP_873317.1 639852 R 233412 CDS NP_873318.1 33151965 1490764 complement(640469..642190) 1 NC_002940.2 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 642190 dipZ 1490764 dipZ Haemophilus ducreyi 35000HP thiol:disulfide interchange protein NP_873318.1 640469 R 233412 CDS NP_873319.1 33151966 1490765 642241..642357 1 NC_002940.2 hypothetical protein 642357 1490765 HD0809 Haemophilus ducreyi 35000HP hypothetical protein NP_873319.1 642241 D 233412 CDS NP_873320.1 33151967 1490766 complement(642354..643316) 1 NC_002940.2 sodium/calcium exchange protein 643316 1490766 HD0810 Haemophilus ducreyi 35000HP sodium/calcium exchange protein NP_873320.1 642354 R 233412 CDS NP_873321.1 33151968 1490767 643486..644220 1 NC_002940.2 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding protein 644220 artP 1490767 artP Haemophilus ducreyi 35000HP arginine transporter ATP-binding protein NP_873321.1 643486 D 233412 CDS NP_873322.1 33151969 1490768 644257..644976 1 NC_002940.2 arginine ABC transporter substrate-binding protein 644976 artI 1490768 artI Haemophilus ducreyi 35000HP arginine ABC transporter substrate-binding protein NP_873322.1 644257 D 233412 CDS NP_873323.1 33151970 1490769 644981..645646 1 NC_002940.2 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 645646 artQ 1490769 artQ Haemophilus ducreyi 35000HP arginine transporter permease subunit ArtQ NP_873323.1 644981 D 233412 CDS NP_873324.1 33151971 1490770 645652..646335 1 NC_002940.2 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 646335 artM 1490770 artM Haemophilus ducreyi 35000HP arginine transporter permease subunit ArtM NP_873324.1 645652 D 233412 CDS NP_873325.1 33151972 1490771 complement(646402..648081) 1 NC_002940.2 DNA repair protein 648081 recN 1490771 recN Haemophilus ducreyi 35000HP DNA repair protein NP_873325.1 646402 R 233412 CDS NP_873326.1 33151973 1490772 complement(648238..649158) 1 NC_002940.2 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 649158 lpxC 1490772 lpxC Haemophilus ducreyi 35000HP UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase NP_873326.1 648238 R 233412 CDS NP_873327.1 33151974 1490773 complement(649189..650379) 1 NC_002940.2 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 650379 ftsZ 1490773 ftsZ Haemophilus ducreyi 35000HP cell division protein FtsZ NP_873327.1 649189 R 233412 CDS NP_873328.1 33151975 1490774 complement(650417..651697) 1 NC_002940.2 cell division protein FtsA 651697 ftsA 1490774 ftsA Haemophilus ducreyi 35000HP cell division protein FtsA NP_873328.1 650417 R 233412 CDS NP_873329.1 33151976 1490775 complement(651728..652519) 1 NC_002940.2 cell division protein FtsQ 652519 ftsQ 1490775 ftsQ Haemophilus ducreyi 35000HP cell division protein FtsQ NP_873329.1 651728 R 233412 CDS NP_873330.1 33151977 1490776 complement(652519..653430) 1 NC_002940.2 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 653430 ddl 1490776 ddl Haemophilus ducreyi 35000HP D-alanine--D-alanine ligase NP_873330.1 652519 R 233412 CDS NP_873331.1 33151978 1490777 complement(653450..654877) 1 NC_002940.2 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 654877 murC 1490777 murC Haemophilus ducreyi 35000HP UDP-N-acetylmuramate--L-alanine ligase NP_873331.1 653450 R 233412 CDS NP_873332.1 33151979 1490778 complement(654912..655979) 1 NC_002940.2 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 655979 murG 1490778 murG Haemophilus ducreyi 35000HP undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase NP_873332.1 654912 R 233412 CDS NP_873333.1 33151980 1490779 complement(656284..656931) 1 NC_002940.2 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 656931 adk 1490779 adk Haemophilus ducreyi 35000HP adenylate kinase NP_873333.1 656284 R 233412 CDS NP_873334.1 33151981 1490780 complement(657033..658316) 1 NC_002940.2 permease and signal transducer AmpG 658316 ampG 1490780 ampG Haemophilus ducreyi 35000HP permease and signal transducer AmpG NP_873334.1 657033 R 233412 CDS NP_873335.1 33151982 1490781 complement(658377..659393) 1 NC_002940.2 UDP-glucose-4-epimerase 659393 galE 1490781 galE Haemophilus ducreyi 35000HP UDP-glucose-4-epimerase NP_873335.1 658377 R 233412 CDS NP_873336.1 33151983 1490782 complement(659456..661516) 1 NC_002940.2 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 661516 ligA 1490782 ligA Haemophilus ducreyi 35000HP NAD-dependent DNA ligase LigA NP_873336.1 659456 R 233412 CDS NP_873337.1 33151984 1490783 complement(661589..662593) 1 NC_002940.2 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 662593 zipA 1490783 zipA Haemophilus ducreyi 35000HP cell division protein ZipA NP_873337.1 661589 R 233412 CDS NP_873338.1 33151985 1490784 662703..663590 1 NC_002940.2 role in sulfur assimilation; sulfate transport protein CysZ 663590 cysZ 1490784 cysZ Haemophilus ducreyi 35000HP sulfate transport protein CysZ NP_873338.1 662703 D 233412 CDS NP_873339.1 33151986 1490785 complement(663662..665116) 1 NC_002940.2 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 665116 gnd 1490785 gnd Haemophilus ducreyi 35000HP 6-phosphogluconate dehydrogenase NP_873339.1 663662 R 233412 CDS NP_873340.1 33151987 1490786 complement(665230..666555) 1 NC_002940.2 transporter 666555 1490786 HD0835 Haemophilus ducreyi 35000HP transporter NP_873340.1 665230 R 233412 CDS NP_873341.1 33151988 1490787 complement(666578..667279) 1 NC_002940.2 catalyzes the formation of 6-phospho-D-gluconate from 6-phospho-D-glucono-1,5-lactone; 6-phosphogluconolactonase 667279 pgl 1490787 pgl Haemophilus ducreyi 35000HP 6-phosphogluconolactonase NP_873341.1 666578 R 233412 CDS NP_873342.1 33151989 1490788 complement(667336..668823) 1 NC_002940.2 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 668823 zwf 1490788 zwf Haemophilus ducreyi 35000HP glucose-6-phosphate 1-dehydrogenase NP_873342.1 667336 R 233412 CDS NP_873343.1 33151990 1490789 complement(668892..669704) 1 NC_002940.2 3'-phosphoadenosine 5'-phosphosulfate 3'-phosphatase 669704 cysQ 1490789 cysQ Haemophilus ducreyi 35000HP 3'-phosphoadenosine 5'-phosphosulfate 3'-phosphatase NP_873343.1 668892 R 233412 CDS NP_873344.1 33151991 1490790 complement(669718..670263) 1 NC_002940.2 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 670263 nudE 1490790 nudE Haemophilus ducreyi 35000HP ADP-ribose diphosphatase NudE NP_873344.1 669718 R 233412 CDS NP_873345.1 33151992 1490791 670384..670803 1 NC_002940.2 heat shock protein 15 670803 hslR 1490791 hslR Haemophilus ducreyi 35000HP heat shock protein 15 NP_873345.1 670384 D 233412 CDS NP_873346.1 33151993 1490792 670876..671769 1 NC_002940.2 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 671769 hslO 1490792 hslO Haemophilus ducreyi 35000HP Hsp33-like chaperonin NP_873346.1 670876 D 233412 CDS NP_873347.1 33151994 1490793 complement(671836..672891) 1 NC_002940.2 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 672891 SohB 1490793 SohB Haemophilus ducreyi 35000HP periplasmic protease NP_873347.1 671836 R 233412 CDS NP_873348.1 33151995 1490794 complement(672926..674098) 1 NC_002940.2 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 674098 lpxB 1490794 lpxB Haemophilus ducreyi 35000HP lipid-A-disaccharide synthase NP_873348.1 672926 R 233412 CDS NP_873349.1 33151996 1490795 complement(674212..675330) 1 NC_002940.2 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 675330 asd 1490795 asd Haemophilus ducreyi 35000HP aspartate-semialdehyde dehydrogenase NP_873349.1 674212 R 233412 CDS NP_873350.1 33151997 1490796 675522..676121 1 NC_002940.2 superoxide dismutase [Cu-Zn] 676121 sodC 1490796 sodC Haemophilus ducreyi 35000HP superoxide dismutase [Cu-Zn] NP_873350.1 675522 D 233412 CDS NP_873351.1 33151998 1490797 complement(676162..677244) 1 NC_002940.2 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 677244 recF 1490797 recF Haemophilus ducreyi 35000HP recombination protein F NP_873351.1 676162 R 233412 CDS NP_873352.1 33151999 1490798 complement(677306..678409) 1 NC_002940.2 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 678409 dnaN 1490798 dnaN Haemophilus ducreyi 35000HP DNA polymerase III subunit beta NP_873352.1 677306 R 233412 CDS NP_873353.1 33152000 1490799 complement(678427..679773) 1 NC_002940.2 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 679773 dnaA 1490799 dnaA Haemophilus ducreyi 35000HP chromosomal replication initiation protein NP_873353.1 678427 R 233412 CDS NP_873354.1 33152001 1490800 679999..681654 1 NC_002940.2 hypothetical protein 681654 1490800 HD0852 Haemophilus ducreyi 35000HP hypothetical protein NP_873354.1 679999 D 233412 CDS NP_873355.1 33152002 1490801 681783..682865 1 NC_002940.2 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 682865 prfA 1490801 prfA Haemophilus ducreyi 35000HP peptide chain release factor 1 NP_873355.1 681783 D 233412 CDS NP_873356.1 33152003 1490802 682982..683854 1 NC_002940.2 protein-glutamine N-methyl transferase 683854 hemK 1490802 hemK Haemophilus ducreyi 35000HP protein-glutamine N-methyl transferase NP_873356.1 682982 D 233412 CDS NP_873357.1 33152004 1490803 683854..684720 1 NC_002940.2 hypothetical protein 684720 1490803 HD0856 Haemophilus ducreyi 35000HP hypothetical protein NP_873357.1 683854 D 233412 CDS NP_873358.1 33152005 1490804 684749..685609 1 NC_002940.2 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 685609 kdsA 1490804 kdsA Haemophilus ducreyi 35000HP 2-dehydro-3-deoxyphosphooctonate aldolase NP_873358.1 684749 D 233412 CDS NP_873359.1 33152006 1490805 685615..686787 1 NC_002940.2 lipoprotein releasing system transmembrane protein 686787 lolC 1490805 lolC Haemophilus ducreyi 35000HP lipoprotein releasing system transmembrane protein NP_873359.1 685615 D 233412 CDS NP_873360.1 33152007 1490806 686872..687552 1 NC_002940.2 lipoprotein releasing system ATP-binding protein 687552 lolD 1490806 lolD Haemophilus ducreyi 35000HP lipoprotein releasing system ATP-binding protein NP_873360.1 686872 D 233412 CDS NP_873361.1 33152008 1490807 687552..688802 1 NC_002940.2 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 688802 lolE 1490807 lolE Haemophilus ducreyi 35000HP outer membrane-specific lipoprotein transporter subunit LolE NP_873361.1 687552 D 233412 CDS NP_873362.1 33152009 1490808 complement(688854..689648) 1 NC_002940.2 peptide transport system ATP-binding protein SapF 689648 sapF 1490808 sapF Haemophilus ducreyi 35000HP peptide transport system ATP-binding protein SapF NP_873362.1 688854 R 233412 CDS NP_873363.1 33152010 1490809 complement(689748..690824) 1 NC_002940.2 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 690824 fbaA 1490809 fbaA Haemophilus ducreyi 35000HP fructose-bisphosphate aldolase NP_873363.1 689748 R 233412 CDS NP_873364.1 33152011 1490810 complement(690932..692107) 1 NC_002940.2 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 692107 pgk 1490810 pgk Haemophilus ducreyi 35000HP phosphoglycerate kinase NP_873364.1 690932 R 233412 CDS NP_873365.1 33152012 1490811 complement(692232..693506) 1 NC_002940.2 sodium/sulfate transporter 693506 1490811 HD0866 Haemophilus ducreyi 35000HP sodium/sulfate transporter NP_873365.1 692232 R 233412 CDS NP_873366.1 33152013 1490812 complement(693762..694103) 1 NC_002940.2 hypothetical protein 694103 1490812 HD0868 Haemophilus ducreyi 35000HP hypothetical protein NP_873366.1 693762 R 233412 CDS NP_873367.1 33152014 1490813 694092..694202 1 NC_002940.2 hypothetical protein 694202 1490813 HD0869 Haemophilus ducreyi 35000HP hypothetical protein NP_873367.1 694092 D 233412 CDS NP_873368.1 33152015 1490814 complement(694332..696248) 1 NC_002940.2 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 696248 parE 1490814 parE Haemophilus ducreyi 35000HP DNA topoisomerase IV subunit B NP_873368.1 694332 R 233412 CDS NP_873369.1 33152016 1490815 696407..696574 1 NC_002940.2 hypothetical protein 696574 1490815 HD0872 Haemophilus ducreyi 35000HP hypothetical protein NP_873369.1 696407 D 233412 CDS NP_873370.1 33152017 1490816 complement(696571..697734) 1 NC_002940.2 includes: chorismate mutase; prephenate dehydratase; P-protein 697734 pheA 1490816 pheA Haemophilus ducreyi 35000HP P-protein NP_873370.1 696571 R 233412 CDS NP_873371.1 33152018 1490817 complement(697916..699202) 1 NC_002940.2 NADH dehydrogenase 699202 ndh 1490817 ndh Haemophilus ducreyi 35000HP NADH dehydrogenase NP_873371.1 697916 R 233412 CDS NP_873372.1 33152019 1490818 complement(699285..699785) 1 NC_002940.2 hypothetical protein 699785 sprT 1490818 sprT Haemophilus ducreyi 35000HP hypothetical protein NP_873372.1 699285 R 233412 CDS NP_873373.1 33152020 1490819 complement(699752..700591) 1 NC_002940.2 ribonuclease 700591 1490819 HD0876 Haemophilus ducreyi 35000HP ribonuclease NP_873373.1 699752 R 233412 CDS NP_873374.1 33152021 1490820 complement(700628..700738) 1 NC_002940.2 hypothetical protein 700738 1490820 HD0877 Haemophilus ducreyi 35000HP hypothetical protein NP_873374.1 700628 R 233412 CDS NP_873375.1 33152022 1490821 complement(700711..702567) 1 NC_002940.2 protease IV, signal peptide peptidase 702567 sppA 1490821 sppA Haemophilus ducreyi 35000HP protease IV, signal peptide peptidase NP_873375.1 700711 R 233412 CDS NP_873376.1 33152023 1490822 702679..703248 1 NC_002940.2 hypothetical protein 703248 1490822 HD0879 Haemophilus ducreyi 35000HP hypothetical protein NP_873376.1 702679 D 233412 CDS NP_873377.1 33152024 1490823 703261..704082 1 NC_002940.2 dehydrogenase 704082 1490823 HD0880 Haemophilus ducreyi 35000HP dehydrogenase NP_873377.1 703261 D 233412 CDS NP_873378.1 33152025 1490824 complement(704079..704825) 1 NC_002940.2 hypothetical protein 704825 1490824 HD0881 Haemophilus ducreyi 35000HP hypothetical protein NP_873378.1 704079 R 233412 CDS NP_873379.1 33152026 1490825 704960..706162 1 NC_002940.2 lipopolysaccharide biosynthesis protein 706162 lsgA 1490825 lsgA Haemophilus ducreyi 35000HP lipopolysaccharide biosynthesis protein NP_873379.1 704960 D 233412 CDS NP_873380.1 33152027 1490826 706181..706975 1 NC_002940.2 lipooligosaccharide N-acetylglucosamine glycosyltransferase 706975 lsgD 1490826 lsgD Haemophilus ducreyi 35000HP lipooligosaccharide N-acetylglucosamine glycosyltransferase NP_873380.1 706181 D 233412 CDS NP_873381.1 33152028 1490827 706956..708140 1 NC_002940.2 hypothetical protein 708140 1490827 HD0884 Haemophilus ducreyi 35000HP hypothetical protein NP_873381.1 706956 D 233412 CDS NP_873382.1 33152029 1490828 708150..709031 1 NC_002940.2 lipooligosaccharide galactosyltransferase 709031 lsgE 1490828 lsgE Haemophilus ducreyi 35000HP lipooligosaccharide galactosyltransferase NP_873382.1 708150 D 233412 CDS NP_873383.1 33152030 1490829 709031..709831 1 NC_002940.2 lipooligosaccharide galactosyltransferase 709831 lsgF 1490829 lsgF Haemophilus ducreyi 35000HP lipooligosaccharide galactosyltransferase NP_873383.1 709031 D 233412 CDS NP_873384.1 33152031 1490830 710136..711404 1 NC_002940.2 nucleoside transporter 711404 1490830 HD0887 Haemophilus ducreyi 35000HP nucleoside transporter NP_873384.1 710136 D 233412 CDS NP_873385.1 33152032 1490831 711556..712332 1 NC_002940.2 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 712332 deoC 1490831 deoC Haemophilus ducreyi 35000HP deoxyribose-phosphate aldolase NP_873385.1 711556 D 233412 CDS NP_873386.1 33152033 1490832 712408..713124 1 NC_002940.2 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 713124 deoD 1490832 deoD Haemophilus ducreyi 35000HP purine nucleoside phosphorylase NP_873386.1 712408 D 233412 CDS NP_873387.1 33152034 1490833 713264..714208 1 NC_002940.2 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; N-acetyl-gamma-glutamyl-phosphate reductase 714208 argC 1490833 argC Haemophilus ducreyi 35000HP N-acetyl-gamma-glutamyl-phosphate reductase NP_873387.1 713264 D 233412 CDS NP_873388.1 33152035 1490834 714218..715072 1 NC_002940.2 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 715072 argB 1490834 argB Haemophilus ducreyi 35000HP acetylglutamate kinase NP_873388.1 714218 D 233412 CDS NP_873389.1 33152036 1490835 715069..716253 1 NC_002940.2 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 716253 argD 1490835 argD Haemophilus ducreyi 35000HP acetylornithine aminotransferase NP_873389.1 715069 D 233412 CDS NP_873390.1 33152037 1490836 complement(716334..717596) 1 NC_002940.2 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 717596 rho 1490836 rho Haemophilus ducreyi 35000HP transcription termination factor Rho NP_873390.1 716334 R 233412 CDS NP_873391.1 33152038 1490837 complement(717778..718728) 1 NC_002940.2 cysteine synthase; O-acetylserine sulfhydrylase 718728 cysK 1490837 cysK Haemophilus ducreyi 35000HP O-acetylserine sulfhydrylase NP_873391.1 717778 R 233412 CDS NP_873392.1 33152039 1490839 complement(719286..720140) 1 NC_002940.2 integrase/recombinase 720140 1490839 HD0897 Haemophilus ducreyi 35000HP integrase/recombinase NP_873392.1 719286 R 233412 CDS NP_873393.1 33152040 1490840 complement(720211..720900) 1 NC_002940.2 hypothetical protein 720900 1490840 HD0898 Haemophilus ducreyi 35000HP hypothetical protein NP_873393.1 720211 R 233412 CDS NP_873394.1 33152041 1490841 complement(720977..721417) 1 NC_002940.2 hypothetical protein 721417 1490841 HD0899 Haemophilus ducreyi 35000HP hypothetical protein NP_873394.1 720977 R 233412 CDS NP_873395.1 33152042 1490842 complement(721421..722074) 1 NC_002940.2 hypothetical protein 722074 1490842 HD0900 Haemophilus ducreyi 35000HP hypothetical protein NP_873395.1 721421 R 233412 CDS NP_873396.1 33152043 1490843 722364..722606 1 NC_002940.2 hypothetical protein 722606 1490843 HD0901 Haemophilus ducreyi 35000HP hypothetical protein NP_873396.1 722364 D 233412 CDS NP_873397.1 33152044 1490844 723239..723910 1 NC_002940.2 cytolethal distending toxin protein A 723910 cdtA 1490844 cdtA Haemophilus ducreyi 35000HP cytolethal distending toxin protein A NP_873397.1 723239 D 233412 CDS NP_873398.1 33152045 1490845 723925..724776 1 NC_002940.2 cytolethal distending toxin protein B 724776 cdtB 1490845 cdtB Haemophilus ducreyi 35000HP cytolethal distending toxin protein B NP_873398.1 723925 D 233412 CDS NP_873399.1 33152046 1490846 724787..725347 1 NC_002940.2 cytolethal distending toxin protein C 725347 cdtC 1490846 cdtC Haemophilus ducreyi 35000HP cytolethal distending toxin protein C NP_873399.1 724787 D 233412 CDS NP_873400.1 33152047 1490847 725682..726008 1 NC_002940.2 IstB , C-terminal fragment 726008 1490847 HD0905 Haemophilus ducreyi 35000HP IstB , C-terminal fragment NP_873400.1 725682 D 233412 CDS NP_873401.1 33152048 1490848 726224..726373 1 NC_002940.2 hypothetical protein 726373 1490848 HD0906 Haemophilus ducreyi 35000HP hypothetical protein NP_873401.1 726224 D 233412 CDS NP_873402.1 33152049 1490849 complement(726539..727120) 1 NC_002940.2 hypothetical protein 727120 1490849 HD0907 Haemophilus ducreyi 35000HP hypothetical protein NP_873402.1 726539 R 233412 CDS NP_873403.1 33152050 1490850 727649..728233 1 NC_002940.2 transposon gamma-delta resolvase 728233 tnpR 1490850 tnpR Haemophilus ducreyi 35000HP transposon gamma-delta resolvase NP_873403.1 727649 D 233412 CDS NP_873404.1 33152051 1490851 complement(728253..728669) 1 NC_002940.2 hypothetical protein 728669 1490851 HD0909 Haemophilus ducreyi 35000HP hypothetical protein NP_873404.1 728253 R 233412 CDS NP_873405.1 33152052 1490852 complement(728678..729181) 1 NC_002940.2 HicB protein 729181 hicB 1490852 hicB Haemophilus ducreyi 35000HP HicB protein NP_873405.1 728678 R 233412 CDS NP_873406.1 33152053 1490853 complement(729191..729445) 1 NC_002940.2 HicA protein 729445 hicA 1490853 hicA Haemophilus ducreyi 35000HP HicA protein NP_873406.1 729191 R 233412 CDS NP_873407.1 33152054 1490854 729797..730264 1 NC_002940.2 hypothetical protein 730264 1490854 HD0912 Haemophilus ducreyi 35000HP hypothetical protein NP_873407.1 729797 D 233412 CDS NP_873408.1 33152055 1490855 complement(730261..731187) 1 NC_002940.2 hypothetical protein 731187 1490855 HD0913 Haemophilus ducreyi 35000HP hypothetical protein NP_873408.1 730261 R 233412 CDS NP_873409.1 33152056 1490856 complement(731304..732062) 1 NC_002940.2 type I restriction enzyme M subunit 732062 1490856 HD0914 Haemophilus ducreyi 35000HP type I restriction enzyme M subunit NP_873409.1 731304 R 233412 CDS NP_873410.1 33152057 1490857 complement(732144..732872) 1 NC_002940.2 hypothetical protein 732872 1490857 HD0915 Haemophilus ducreyi 35000HP hypothetical protein NP_873410.1 732144 R 233412 CDS NP_873411.1 33152058 1490858 complement(732982..733926) 1 NC_002940.2 DNA primase 733926 traC 1490858 traC Haemophilus ducreyi 35000HP DNA primase NP_873411.1 732982 R 233412 CDS NP_873412.1 33152059 1490859 complement(734003..734287) 1 NC_002940.2 hypothetical protein 734287 1490859 HD0918 Haemophilus ducreyi 35000HP hypothetical protein NP_873412.1 734003 R 233412 CDS NP_873413.1 33152060 1490860 complement(734362..734700) 1 NC_002940.2 hypothetical protein 734700 1490860 HD0919 Haemophilus ducreyi 35000HP hypothetical protein NP_873413.1 734362 R 233412 CDS NP_873414.1 33152061 1490861 735343..735513 1 NC_002940.2 hypothetical protein 735513 1490861 HD0920 Haemophilus ducreyi 35000HP hypothetical protein NP_873414.1 735343 D 233412 CDS NP_873415.1 33152062 1490862 735782..736438 1 NC_002940.2 hypothetical protein 736438 1490862 HD0921 Haemophilus ducreyi 35000HP hypothetical protein NP_873415.1 735782 D 233412 CDS NP_873416.1 33152063 1490863 736465..738462 1 NC_002940.2 hypothetical protein 738462 1490863 HD0922 Haemophilus ducreyi 35000HP hypothetical protein NP_873416.1 736465 D 233412 CDS NP_873417.1 33152064 1490864 738479..738826 1 NC_002940.2 hypothetical protein 738826 1490864 HD0923 Haemophilus ducreyi 35000HP hypothetical protein NP_873417.1 738479 D 233412 CDS NP_873418.1 33152065 1490865 738977..739444 1 NC_002940.2 hypothetical protein 739444 1490865 HD0924 Haemophilus ducreyi 35000HP hypothetical protein NP_873418.1 738977 D 233412 CDS NP_873419.1 33152066 1490866 739428..739559 1 NC_002940.2 hypothetical protein 739559 1490866 HD0925 Haemophilus ducreyi 35000HP hypothetical protein NP_873419.1 739428 D 233412 CDS NP_873420.1 33152067 1490867 complement(739493..739924) 1 NC_002940.2 hypothetical protein 739924 1490867 HD0926 Haemophilus ducreyi 35000HP hypothetical protein NP_873420.1 739493 R 233412 CDS NP_873421.1 33152068 1490868 complement(740037..740180) 1 NC_002940.2 hypothetical protein 740180 1490868 HD0927 Haemophilus ducreyi 35000HP hypothetical protein NP_873421.1 740037 R 233412 CDS NP_873422.1 33152069 1490869 complement(740201..741004) 1 NC_002940.2 hypothetical protein 741004 1490869 HD0928 Haemophilus ducreyi 35000HP hypothetical protein NP_873422.1 740201 R 233412 CDS NP_873423.1 33152070 1490870 complement(741017..741349) 1 NC_002940.2 hypothetical protein 741349 1490870 HD0930 Haemophilus ducreyi 35000HP hypothetical protein NP_873423.1 741017 R 233412 CDS NP_873424.1 33152071 1490871 complement(741330..741785) 1 NC_002940.2 hypothetical protein 741785 1490871 HD0931 Haemophilus ducreyi 35000HP hypothetical protein NP_873424.1 741330 R 233412 CDS NP_873425.1 33152072 1490872 complement(741757..742149) 1 NC_002940.2 hypothetical protein 742149 1490872 HD0932 Haemophilus ducreyi 35000HP hypothetical protein NP_873425.1 741757 R 233412 CDS NP_873426.1 33152073 1490873 complement(742130..744538) 1 NC_002940.2 hypothetical protein 744538 1490873 HD0933 Haemophilus ducreyi 35000HP hypothetical protein NP_873426.1 742130 R 233412 CDS NP_873427.1 33152074 1490874 complement(744538..744945) 1 NC_002940.2 hypothetical protein 744945 1490874 HD0934 Haemophilus ducreyi 35000HP hypothetical protein NP_873427.1 744538 R 233412 CDS NP_873428.1 33152075 1490875 complement(744962..746407) 1 NC_002940.2 hypothetical protein 746407 1490875 HD0935 Haemophilus ducreyi 35000HP hypothetical protein NP_873428.1 744962 R 233412 CDS NP_873429.1 33152076 1490876 complement(746420..747280) 1 NC_002940.2 hypothetical protein 747280 1490876 HD0936 Haemophilus ducreyi 35000HP hypothetical protein NP_873429.1 746420 R 233412 CDS NP_873430.1 33152077 1490877 complement(747344..747919) 1 NC_002940.2 hypothetical protein 747919 1490877 HD0937 Haemophilus ducreyi 35000HP hypothetical protein NP_873430.1 747344 R 233412 CDS NP_873431.1 33152078 1490878 complement(747931..748305) 1 NC_002940.2 hypothetical protein 748305 1490878 HD0938 Haemophilus ducreyi 35000HP hypothetical protein NP_873431.1 747931 R 233412 CDS NP_873432.1 33152079 1490879 complement(748323..748712) 1 NC_002940.2 hypothetical protein 748712 1490879 HD0939 Haemophilus ducreyi 35000HP hypothetical protein NP_873432.1 748323 R 233412 CDS NP_873433.1 33152080 1490880 complement(748972..749298) 1 NC_002940.2 hypothetical protein 749298 1490880 HD0940 Haemophilus ducreyi 35000HP hypothetical protein NP_873433.1 748972 R 233412 CDS NP_873434.1 33152081 1490881 complement(749465..750151) 1 NC_002940.2 hypothetical protein 750151 1490881 HD0941 Haemophilus ducreyi 35000HP hypothetical protein NP_873434.1 749465 R 233412 CDS NP_873435.1 33152082 1490882 complement(750151..750477) 1 NC_002940.2 hypothetical protein 750477 1490882 HD0942 Haemophilus ducreyi 35000HP hypothetical protein NP_873435.1 750151 R 233412 CDS NP_873436.1 33152083 1490883 complement(750478..750717) 1 NC_002940.2 hypothetical protein 750717 1490883 HD0943 Haemophilus ducreyi 35000HP hypothetical protein NP_873436.1 750478 R 233412 CDS NP_873437.1 33152084 1490884 complement(750624..751232) 1 NC_002940.2 hypothetical protein 751232 1490884 HD0944 Haemophilus ducreyi 35000HP hypothetical protein NP_873437.1 750624 R 233412 CDS NP_873438.1 33152085 1490885 complement(751351..751824) 1 NC_002940.2 DNA repair protein 751824 1490885 HD0945 Haemophilus ducreyi 35000HP DNA repair protein NP_873438.1 751351 R 233412 CDS NP_873439.1 33152086 1490886 complement(751906..752250) 1 NC_002940.2 hypothetical protein 752250 1490886 HD0946 Haemophilus ducreyi 35000HP hypothetical protein NP_873439.1 751906 R 233412 CDS NP_873440.1 33152087 1490887 complement(752505..752786) 1 NC_002940.2 hypothetical protein 752786 1490887 HD0947 Haemophilus ducreyi 35000HP hypothetical protein NP_873440.1 752505 R 233412 CDS NP_873441.1 33152088 1490888 complement(752898..753062) 1 NC_002940.2 hypothetical protein 753062 1490888 HD0948 Haemophilus ducreyi 35000HP hypothetical protein NP_873441.1 752898 R 233412 CDS NP_873442.1 33152089 1490889 complement(753101..753550) 1 NC_002940.2 hypothetical protein 753550 1490889 HD0950 Haemophilus ducreyi 35000HP hypothetical protein NP_873442.1 753101 R 233412 CDS NP_873443.1 33152090 1490890 complement(753611..754084) 1 NC_002940.2 hypothetical protein 754084 1490890 HD0951 Haemophilus ducreyi 35000HP hypothetical protein NP_873443.1 753611 R 233412 CDS NP_873444.1 33152091 1490891 complement(754179..754394) 1 NC_002940.2 hypothetical protein 754394 1490891 HD0952 Haemophilus ducreyi 35000HP hypothetical protein NP_873444.1 754179 R 233412 CDS NP_873445.1 33152092 1490892 754809..755018 1 NC_002940.2 hypothetical protein 755018 1490892 HD0953 Haemophilus ducreyi 35000HP hypothetical protein NP_873445.1 754809 D 233412 CDS NP_873446.1 33152093 1490893 complement(755180..756691) 1 NC_002940.2 DNA topoisomerase III 756691 topB1 1490893 topB1 Haemophilus ducreyi 35000HP DNA topoisomerase III NP_873446.1 755180 R 233412 CDS NP_873447.1 33152094 1490894 complement(756688..756885) 1 NC_002940.2 filamentous phage CTX RstR-like repressor 756885 1490894 HD0955 Haemophilus ducreyi 35000HP filamentous phage CTX RstR-like repressor NP_873447.1 756688 R 233412 CDS NP_873448.1 33152095 1490895 757015..758004 1 NC_002940.2 hypothetical protein 758004 1490895 HD0956 Haemophilus ducreyi 35000HP hypothetical protein NP_873448.1 757015 D 233412 CDS NP_873449.1 33152096 1490896 complement(757973..758374) 1 NC_002940.2 hypothetical protein 758374 1490896 HD0957 Haemophilus ducreyi 35000HP hypothetical protein NP_873449.1 757973 R 233412 CDS NP_873450.1 33152097 1490897 complement(758470..758700) 1 NC_002940.2 hypothetical protein 758700 1490897 HD0958 Haemophilus ducreyi 35000HP hypothetical protein NP_873450.1 758470 R 233412 CDS NP_873451.1 33152098 1490898 758979..759077 1 NC_002940.2 hypothetical protein 759077 1490898 HD0959 Haemophilus ducreyi 35000HP hypothetical protein NP_873451.1 758979 D 233412 CDS NP_873452.1 33152099 1490899 complement(758989..759486) 1 NC_002940.2 hypothetical protein 759486 1490899 HD0960 Haemophilus ducreyi 35000HP hypothetical protein NP_873452.1 758989 R 233412 CDS NP_873453.1 33152100 1490900 complement(759539..760042) 1 NC_002940.2 hypothetical protein 760042 1490900 HD0961 Haemophilus ducreyi 35000HP hypothetical protein NP_873453.1 759539 R 233412 CDS NP_873454.1 33152101 1490901 complement(760133..760549) 1 NC_002940.2 single-stranded DNA-binding protein 760549 ssb2 1490901 ssb2 Haemophilus ducreyi 35000HP single-stranded DNA-binding protein NP_873454.1 760133 R 233412 CDS NP_873455.1 33152102 1490902 complement(760905..761153) 1 NC_002940.2 hypothetical protein 761153 1490902 HD0963 Haemophilus ducreyi 35000HP hypothetical protein NP_873455.1 760905 R 233412 CDS NP_873456.1 33152103 1490903 complement(761289..761438) 1 NC_002940.2 hypothetical protein 761438 1490903 HD0964 Haemophilus ducreyi 35000HP hypothetical protein NP_873456.1 761289 R 233412 CDS NP_873457.1 33152104 1490904 761531..761623 1 NC_002940.2 hypothetical protein 761623 1490904 HD0965 Haemophilus ducreyi 35000HP hypothetical protein NP_873457.1 761531 D 233412 CDS NP_873458.1 33152105 1490905 complement(761795..762562) 1 NC_002940.2 hypothetical protein 762562 1490905 HD0966 Haemophilus ducreyi 35000HP hypothetical protein NP_873458.1 761795 R 233412 CDS NP_873459.1 33152106 1490906 complement(762639..763016) 1 NC_002940.2 hypothetical protein 763016 1490906 HD0967 Haemophilus ducreyi 35000HP hypothetical protein NP_873459.1 762639 R 233412 CDS NP_873460.1 33152107 1490907 complement(763036..763803) 1 NC_002940.2 hypothetical protein 763803 1490907 HD0968 Haemophilus ducreyi 35000HP hypothetical protein NP_873460.1 763036 R 233412 CDS NP_873461.1 33152108 1490908 complement(764006..764563) 1 NC_002940.2 hypothetical protein 764563 1490908 HD0969 Haemophilus ducreyi 35000HP hypothetical protein NP_873461.1 764006 R 233412 CDS NP_873462.1 33152109 1490909 complement(764550..765248) 1 NC_002940.2 hypothetical protein 765248 1490909 HD0970 Haemophilus ducreyi 35000HP hypothetical protein NP_873462.1 764550 R 233412 CDS NP_873463.1 33152110 1490910 complement(765230..765877) 1 NC_002940.2 hypothetical protein 765877 1490910 HD0971 Haemophilus ducreyi 35000HP hypothetical protein NP_873463.1 765230 R 233412 CDS NP_873464.1 33152111 1490911 complement(765930..766166) 1 NC_002940.2 hypothetical protein 766166 1490911 HD0972 Haemophilus ducreyi 35000HP hypothetical protein NP_873464.1 765930 R 233412 CDS NP_873465.1 33152112 1490912 complement(766159..767535) 1 NC_002940.2 replicative DNA helicase 767535 dnaB1 1490912 dnaB1 Haemophilus ducreyi 35000HP replicative DNA helicase NP_873465.1 766159 R 233412 CDS NP_873466.1 33152113 1490913 complement(767541..768374) 1 NC_002940.2 chromosome partitioning-like protein 768374 1490913 HD0974 Haemophilus ducreyi 35000HP chromosome partitioning-like protein NP_873466.1 767541 R 233412 CDS NP_873467.1 33152114 1490917 complement(768923..772405) 1 NC_002940.2 transcription repair coupling factor 772405 mfd 1490917 mfd Haemophilus ducreyi 35000HP transcription repair coupling factor NP_873467.1 768923 R 233412 CDS NP_873468.1 33152115 1490918 772508..775117 1 NC_002940.2 aminopeptidase 775117 pepN 1490918 pepN Haemophilus ducreyi 35000HP aminopeptidase NP_873468.1 772508 D 233412 CDS NP_873469.1 33152116 1490919 complement(775228..775827) 1 NC_002940.2 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 775827 1490919 HD0977 Haemophilus ducreyi 35000HP glycerol-3-phosphate acyltransferase PlsY NP_873469.1 775228 R 233412 CDS NP_873470.1 33152117 1490920 775887..776258 1 NC_002940.2 dihydroneopterin aldolase 776258 folB 1490920 folB Haemophilus ducreyi 35000HP dihydroneopterin aldolase NP_873470.1 775887 D 233412 CDS NP_873471.1 33152118 1490921 776341..777240 1 NC_002940.2 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 777240 cdd 1490921 cdd Haemophilus ducreyi 35000HP cytidine deaminase NP_873471.1 776341 D 233412 CDS NP_873472.1 33152119 1490922 complement(777282..778220) 1 NC_002940.2 ABC transporter membrane protein; cell division protein FtsX 778220 ftsX 1490922 ftsX Haemophilus ducreyi 35000HP cell division protein FtsX NP_873472.1 777282 R 233412 CDS NP_873473.1 33152120 1490923 complement(778230..778883) 1 NC_002940.2 cell division ATP-binding protein FtsE 778883 fstE 1490923 fstE Haemophilus ducreyi 35000HP cell division ATP-binding protein FtsE NP_873473.1 778230 R 233412 CDS NP_873474.1 33152121 1490924 complement(778922..780481) 1 NC_002940.2 cell division protein FtsY 780481 ftsY 1490924 ftsY Haemophilus ducreyi 35000HP cell division protein FtsY NP_873474.1 778922 R 233412 CDS NP_873475.1 33152122 1490925 780561..781154 1 NC_002940.2 hypothetical protein 781154 1490925 HD0985 Haemophilus ducreyi 35000HP hypothetical protein NP_873475.1 780561 D 233412 CDS NP_873476.1 33152123 1490926 781201..781512 1 NC_002940.2 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 781512 1490926 HD0986 Haemophilus ducreyi 35000HP dsDNA-mimic protein NP_873476.1 781201 D 233412 CDS NP_873477.1 33152124 1490927 781528..782037 1 NC_002940.2 Flavin:NADH oxidoreductase component; 4-hydroxyphenylacetic acid hydroxylase coupling protein 782037 hpaC 1490927 hpaC Haemophilus ducreyi 35000HP 4-hydroxyphenylacetic acid hydroxylase coupling protein NP_873477.1 781528 D 233412 CDS NP_873478.1 33152125 1490928 complement(782105..784135) 1 NC_002940.2 oligopeptidase A 784135 prlC 1490928 prlC Haemophilus ducreyi 35000HP oligopeptidase A NP_873478.1 782105 R 233412 CDS NP_873479.1 33152126 1490929 complement(784262..784996) 1 NC_002940.2 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 784996 pflA 1490929 pflA Haemophilus ducreyi 35000HP pyruvate formate lyase-activating enzyme 1 NP_873479.1 784262 R 233412 CDS NP_873480.1 33152127 1490930 complement(785164..787476) 1 NC_002940.2 formate acetyltransferase 787476 pflB 1490930 pflB Haemophilus ducreyi 35000HP formate acetyltransferase NP_873480.1 785164 R 233412 CDS NP_873481.1 33152128 1490931 complement(787574..788398) 1 NC_002940.2 formate transporter 788398 focA 1490931 focA Haemophilus ducreyi 35000HP formate transporter NP_873481.1 787574 R 233412 CDS NP_873482.1 33152129 1490932 788667..789092 1 NC_002940.2 hypothetical protein 789092 1490932 HD0992 Haemophilus ducreyi 35000HP hypothetical protein NP_873482.1 788667 D 233412 CDS NP_873483.1 33152130 1490933 complement(789058..789150) 1 NC_002940.2 hypothetical protein 789150 1490933 HD0993 Haemophilus ducreyi 35000HP hypothetical protein NP_873483.1 789058 R 233412 CDS NP_873484.1 33152131 1490934 complement(789156..790202) 1 NC_002940.2 spermidine/putrescine-binding periplasmic protein (SPBP) 790202 potD1 1490934 potD1 Haemophilus ducreyi 35000HP spermidine/putrescine-binding periplasmic protein (SPBP) NP_873484.1 789156 R 233412 CDS NP_873485.1 33152132 1490935 complement(790412..791503) 1 NC_002940.2 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 791503 1490935 HD0995 Haemophilus ducreyi 35000HP GTP-dependent nucleic acid-binding protein EngD NP_873485.1 790412 R 233412 CDS NP_873486.1 33152133 1490936 complement(791604..792206) 1 NC_002940.2 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 792206 pth 1490936 pth Haemophilus ducreyi 35000HP peptidyl-tRNA hydrolase NP_873486.1 791604 R 233412 CDS NP_873487.1 33152134 1490937 complement(792207..792359) 1 NC_002940.2 hypothetical protein 792359 1490937 HD0997 Haemophilus ducreyi 35000HP hypothetical protein NP_873487.1 792207 R 233412 CDS NP_873488.1 33152135 1490938 complement(792361..793587) 1 NC_002940.2 uracil permease 793587 uraA 1490938 uraA Haemophilus ducreyi 35000HP uracil permease NP_873488.1 792361 R 233412 CDS NP_873489.1 33152136 1490939 complement(793737..795260) 1 NC_002940.2 sodium/proline symporter, proline permease 795260 putP 1490939 putP Haemophilus ducreyi 35000HP sodium/proline symporter, proline permease NP_873489.1 793737 R 233412 CDS NP_873490.1 33152137 1490940 complement(795558..795710) 1 NC_002940.2 hypothetical protein 795710 1490940 HD1000 Haemophilus ducreyi 35000HP hypothetical protein NP_873490.1 795558 R 233412 CDS NP_873491.1 33152138 1490941 complement(796176..796586) 1 NC_002940.2 hypothetical protein 796586 1490941 HD1001 Haemophilus ducreyi 35000HP hypothetical protein NP_873491.1 796176 R 233412 CDS NP_873492.1 33152139 1490942 796572..797123 1 NC_002940.2 hypothetical protein 797123 1490942 HD1002 Haemophilus ducreyi 35000HP hypothetical protein NP_873492.1 796572 D 233412 CDS NP_873493.1 33152140 1490943 797179..797769 1 NC_002940.2 hypothetical protein 797769 1490943 HD1003 Haemophilus ducreyi 35000HP hypothetical protein NP_873493.1 797179 D 233412 CDS NP_873494.1 33152141 1490944 797905..798177 1 NC_002940.2 DNA-binding protein HU 798177 hupA 1490944 hupA Haemophilus ducreyi 35000HP DNA-binding protein HU NP_873494.1 797905 D 233412 CDS NP_873495.1 33152142 1490945 complement(798241..799092) 1 NC_002940.2 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 799092 thyA 1490945 thyA Haemophilus ducreyi 35000HP thymidylate synthase NP_873495.1 798241 R 233412 CDS NP_873496.1 33152143 1490946 799193..799762 1 NC_002940.2 hypothetical protein 799762 1490946 HD1006 Haemophilus ducreyi 35000HP hypothetical protein NP_873496.1 799193 D 233412 CDS NP_873497.1 33152144 1490947 799854..800858 1 NC_002940.2 biotin synthetase 800858 bioB 1490947 bioB Haemophilus ducreyi 35000HP biotin synthetase NP_873497.1 799854 D 233412 CDS NP_873498.1 33152145 1490948 complement(800910..801119) 1 NC_002940.2 cold shock-like protein CspC 801119 cspC 1490948 cspC Haemophilus ducreyi 35000HP cold shock-like protein CspC NP_873498.1 800910 R 233412 CDS NP_873499.1 33152146 1490949 801490..802038 1 NC_002940.2 affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 802038 proQ 1490949 proQ Haemophilus ducreyi 35000HP solute/DNA competence effector NP_873499.1 801490 D 233412 CDS NP_873500.1 33152147 1490950 802103..804169 1 NC_002940.2 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 804169 prc 1490950 prc Haemophilus ducreyi 35000HP carboxy-terminal protease NP_873500.1 802103 D 233412 CDS NP_873501.1 33152148 1490951 804267..804506 1 NC_002940.2 hypothetical protein 804506 1490951 HD1011 Haemophilus ducreyi 35000HP hypothetical protein NP_873501.1 804267 D 233412 CDS NP_873502.1 33152149 1490952 complement(805434..805664) 1 NC_002940.2 hypothetical protein 805664 1490952 HD1013 Haemophilus ducreyi 35000HP hypothetical protein NP_873502.1 805434 R 233412 CDS NP_873503.1 33152150 1490953 complement(805718..806095) 1 NC_002940.2 hypothetical protein 806095 1490953 HD1014 Haemophilus ducreyi 35000HP hypothetical protein NP_873503.1 805718 R 233412 CDS NP_873504.1 33152151 1490954 complement(806255..806404) 1 NC_002940.2 hypothetical protein 806404 1490954 HD1015 Haemophilus ducreyi 35000HP hypothetical protein NP_873504.1 806255 R 233412 CDS NP_873505.1 33152152 1490955 complement(806377..806523) 1 NC_002940.2 hypothetical protein 806523 1490955 HD1016 Haemophilus ducreyi 35000HP hypothetical protein NP_873505.1 806377 R 233412 CDS NP_873506.1 33152153 1490956 807600..808031 1 NC_002940.2 hypothetical protein 808031 1490956 HD1017 Haemophilus ducreyi 35000HP hypothetical protein NP_873506.1 807600 D 233412 CDS NP_873507.1 33152154 1490957 808192..809364 1 NC_002940.2 macrolide-specific efflux protein 809364 macA 1490957 macA Haemophilus ducreyi 35000HP macrolide-specific efflux protein NP_873507.1 808192 D 233412 CDS NP_873508.1 33152155 1490958 809613..811703 1 NC_002940.2 macrolide-specific ABC-type efflux carrier 811703 macB 1490958 macB Haemophilus ducreyi 35000HP macrolide-specific ABC-type efflux carrier NP_873508.1 809613 D 233412 CDS NP_873509.1 33152156 1490959 812185..812814 1 NC_002940.2 glyoxalase II family protein 812814 1490959 HD1020 Haemophilus ducreyi 35000HP glyoxalase II family protein NP_873509.1 812185 D 233412 CDS NP_873510.1 33152157 1490960 complement(812807..813574) 1 NC_002940.2 hypothetical protein 813574 1490960 HD1021 Haemophilus ducreyi 35000HP hypothetical protein NP_873510.1 812807 R 233412 CDS NP_873511.1 33152158 1490961 complement(813571..813948) 1 NC_002940.2 hypothetical protein 813948 1490961 HD1022 Haemophilus ducreyi 35000HP hypothetical protein NP_873511.1 813571 R 233412 CDS NP_873512.1 33152159 1490962 complement(813950..814312) 1 NC_002940.2 histidine triad, HIT-like protein 814312 1490962 HD1023 Haemophilus ducreyi 35000HP histidine triad, HIT-like protein NP_873512.1 813950 R 233412 CDS NP_873513.1 33152160 1490963 complement(814390..815220) 1 NC_002940.2 iron (chelated) transport system membrane protein 815220 yfeD 1490963 yfeD Haemophilus ducreyi 35000HP iron (chelated) transport system membrane protein NP_873513.1 814390 R 233412 CDS NP_873514.1 33152161 1490964 complement(815213..816070) 1 NC_002940.2 iron (chelated) transport system membrane protein 816070 yfeC 1490964 yfeC Haemophilus ducreyi 35000HP iron (chelated) transport system membrane protein NP_873514.1 815213 R 233412 CDS NP_873515.1 33152162 1490965 complement(816071..816664) 1 NC_002940.2 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 816664 rnhB 1490965 rnhB Haemophilus ducreyi 35000HP ribonuclease HII NP_873515.1 816071 R 233412 CDS NP_873516.1 33152163 1490966 complement(816681..817709) 1 NC_002940.2 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 817709 1490966 HD1027 Haemophilus ducreyi 35000HP ribosome-associated GTPase NP_873516.1 816681 R 233412 CDS NP_873517.1 33152164 1490967 818228..819121 1 NC_002940.2 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 819121 gcvA 1490967 gcvA Haemophilus ducreyi 35000HP DNA-binding transcriptional activator GcvA NP_873517.1 818228 D 233412 CDS NP_873518.1 33152165 1490968 819118..819804 1 NC_002940.2 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 819804 1490968 HD1029 Haemophilus ducreyi 35000HP nucleotidase NP_873518.1 819118 D 233412 CDS NP_873519.1 33152166 1490969 819801..820784 1 NC_002940.2 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 820784 cysB 1490969 cysB Haemophilus ducreyi 35000HP transcriptional regulator CysB NP_873519.1 819801 D 233412 CDS NP_873520.1 33152167 1490970 820785..821429 1 NC_002940.2 hypothetical protein 821429 1490970 HD1031 Haemophilus ducreyi 35000HP hypothetical protein NP_873520.1 820785 D 233412 CDS NP_873521.1 33152168 1490971 821593..823782 1 NC_002940.2 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 823782 uvrD 1490971 uvrD Haemophilus ducreyi 35000HP DNA-dependent helicase II NP_873521.1 821593 D 233412 CDS NP_873522.1 33152169 1490972 823942..825318 1 NC_002940.2 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 825318 argH 1490972 argH Haemophilus ducreyi 35000HP argininosuccinate lyase NP_873522.1 823942 D 233412 CDS NP_873523.1 33152170 1490973 complement(825390..826940) 1 NC_002940.2 integral membrane sulfate transporter 826940 1490973 HD1034 Haemophilus ducreyi 35000HP integral membrane sulfate transporter NP_873523.1 825390 R 233412 CDS NP_873524.1 33152171 1490974 827192..828163 1 NC_002940.2 hypothetical protein 828163 1490974 HD1036 Haemophilus ducreyi 35000HP hypothetical protein NP_873524.1 827192 D 233412 CDS NP_873525.1 33152172 1490975 828171..829280 1 NC_002940.2 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 829280 ispG 1490975 ispG Haemophilus ducreyi 35000HP 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase NP_873525.1 828171 D 233412 CDS NP_873526.1 33152173 1490976 829393..830664 1 NC_002940.2 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 830664 hisS 1490976 hisS Haemophilus ducreyi 35000HP histidyl-tRNA synthetase NP_873526.1 829393 D 233412 CDS NP_873527.1 33152174 1490977 830701..831324 1 NC_002940.2 hypothetical protein 831324 1490977 HD1040 Haemophilus ducreyi 35000HP hypothetical protein NP_873527.1 830701 D 233412 CDS NP_873528.1 33152175 1490978 831446..832129 1 NC_002940.2 hypothetical protein 832129 1490978 HD1041 Haemophilus ducreyi 35000HP hypothetical protein NP_873528.1 831446 D 233412 CDS NP_873529.1 33152176 1490980 833112..833291 1 NC_002940.2 hypothetical protein 833291 1490980 HD1044 Haemophilus ducreyi 35000HP hypothetical protein NP_873529.1 833112 D 233412 CDS NP_873530.1 33152177 1490981 833324..833698 1 NC_002940.2 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 833698 rpsF 1490981 rpsF Haemophilus ducreyi 35000HP 30S ribosomal protein S6 NP_873530.1 833324 D 233412 CDS NP_873531.1 33152178 1490982 833673..834047 1 NC_002940.2 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 834047 priB 1490982 priB Haemophilus ducreyi 35000HP primosomal replication protein N NP_873531.1 833673 D 233412 CDS NP_873532.1 33152179 1490983 834022..834249 1 NC_002940.2 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 834249 rpsR 1490983 rpsR Haemophilus ducreyi 35000HP 30S ribosomal protein S18 NP_873532.1 834022 D 233412 CDS NP_873533.1 33152180 1490984 834267..834716 1 NC_002940.2 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 834716 rplI 1490984 rplI Haemophilus ducreyi 35000HP 50S ribosomal protein L9 NP_873533.1 834267 D 233412 CDS NP_873534.1 33152181 1490985 834976..835719 1 NC_002940.2 hypothetical protein 835719 1490985 HD1049 Haemophilus ducreyi 35000HP hypothetical protein NP_873534.1 834976 D 233412 CDS NP_873535.1 33152182 1490986 complement(835737..836489) 1 NC_002940.2 ubiquinone/menaquinone biosynthesis methyltransferase 836489 1490986 HD1050 Haemophilus ducreyi 35000HP ubiquinone/menaquinone biosynthesis methyltransferase NP_873535.1 835737 R 233412 CDS NP_873536.1 33152183 1490987 836666..837283 1 NC_002940.2 hypothetical protein 837283 1490987 HD1051 Haemophilus ducreyi 35000HP hypothetical protein NP_873536.1 836666 D 233412 CDS NP_873537.1 33152184 1490988 837343..838407 1 NC_002940.2 pseudouridine synthase 838407 1490988 HD1052 Haemophilus ducreyi 35000HP pseudouridine synthase NP_873537.1 837343 D 233412 CDS NP_873538.1 33152185 1490989 complement(838510..838926) 1 NC_002940.2 nucleoside diphosphate kinase 838926 ndk 1490989 ndk Haemophilus ducreyi 35000HP nucleoside diphosphate kinase NP_873538.1 838510 R 233412 CDS NP_873539.1 33152186 1490990 complement(838996..841050) 1 NC_002940.2 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 841050 metG 1490990 metG Haemophilus ducreyi 35000HP methionyl-tRNA synthetase NP_873539.1 838996 R 233412 CDS NP_873540.1 33152187 1490991 841198..842175 1 NC_002940.2 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 842175 menC 1490991 menC Haemophilus ducreyi 35000HP O-succinylbenzoate synthase NP_873540.1 841198 D 233412 CDS NP_873541.1 33152188 1490992 842281..842973 1 NC_002940.2 ribosomal small subunit pseudouridine synthase A 842973 rsuA 1490992 rsuA Haemophilus ducreyi 35000HP ribosomal small subunit pseudouridine synthase A NP_873541.1 842281 D 233412 CDS NP_873542.1 33152189 1490993 complement(843048..843428) 1 NC_002940.2 hypothetical protein 843428 1490993 HD1060 Haemophilus ducreyi 35000HP hypothetical protein NP_873542.1 843048 R 233412 CDS NP_873543.1 33152190 1490994 complement(843508..844062) 1 NC_002940.2 hypothetical protein 844062 1490994 HD1061 Haemophilus ducreyi 35000HP hypothetical protein NP_873543.1 843508 R 233412 CDS NP_873544.1 33152191 1490995 844116..844961 1 NC_002940.2 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 844961 nfo 1490995 nfo Haemophilus ducreyi 35000HP endonuclease IV NP_873544.1 844116 D 233412 CDS NP_873545.1 33152192 1490996 complement(845042..845497) 1 NC_002940.2 hypothetical protein 845497 1490996 HD1063 Haemophilus ducreyi 35000HP hypothetical protein NP_873545.1 845042 R 233412 CDS NP_873546.1 33152193 1490997 complement(845726..846112) 1 NC_002940.2 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 846112 1490997 HD1064 Haemophilus ducreyi 35000HP autonomous glycyl radical cofactor GrcA NP_873546.1 845726 R 233412 CDS NP_873547.1 33152194 1490998 complement(846171..846275) 1 NC_002940.2 hypothetical protein 846275 1490998 HD1065 Haemophilus ducreyi 35000HP hypothetical protein NP_873547.1 846171 R 233412 CDS NP_873548.1 33152195 1490999 846314..846985 1 NC_002940.2 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 846985 ung 1490999 ung Haemophilus ducreyi 35000HP uracil-DNA glycosylase NP_873548.1 846314 D 233412 CDS NP_873549.1 33152196 1491001 complement(850833..851027) 1 NC_002940.2 hypothetical protein 851027 1491001 HD1070 Haemophilus ducreyi 35000HP hypothetical protein NP_873549.1 850833 R 233412 CDS NP_873550.1 33152197 1491002 complement(851085..851537) 1 NC_002940.2 hypothetical protein 851537 1491002 HD1071 Haemophilus ducreyi 35000HP hypothetical protein NP_873550.1 851085 R 233412 CDS NP_873551.1 33152198 1491003 complement(851650..852246) 1 NC_002940.2 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 852246 grpE 1491003 grpE Haemophilus ducreyi 35000HP heat shock protein GrpE NP_873551.1 851650 R 233412 CDS NP_873552.1 33152199 1491004 852497..853576 1 NC_002940.2 spermidine/putrescine-binding periplasmic protein (SPBP) 853576 potD2 1491004 potD2 Haemophilus ducreyi 35000HP spermidine/putrescine-binding periplasmic protein (SPBP) NP_873552.1 852497 D 233412 CDS NP_873553.1 33152200 1491005 853720..855111 1 NC_002940.2 multidrug resistance protein NorM 855111 norM 1491005 norM Haemophilus ducreyi 35000HP multidrug resistance protein NorM NP_873553.1 853720 D 233412 CDS NP_873554.1 33152201 1491006 855164..858760 1 NC_002940.2 exodeoxyribonuclease V subunit beta 858760 recB 1491006 recB Haemophilus ducreyi 35000HP exodeoxyribonuclease V subunit beta NP_873554.1 855164 D 233412 CDS NP_873555.1 33152202 1491007 complement(858836..859393) 1 NC_002940.2 methylated-DNA--protein-cysteine S-methyltransferase 859393 ogt 1491007 ogt Haemophilus ducreyi 35000HP methylated-DNA--protein-cysteine S-methyltransferase NP_873555.1 858836 R 233412 CDS NP_873556.1 33152203 1491008 complement(859457..860764) 1 NC_002940.2 outer membrane protein P1 860764 ompP1 1491008 ompP1 Haemophilus ducreyi 35000HP outer membrane protein P1 NP_873556.1 859457 R 233412 CDS NP_873557.1 33152204 1491009 860922..861029 1 NC_002940.2 hypothetical protein 861029 1491009 HD1079 Haemophilus ducreyi 35000HP hypothetical protein NP_873557.1 860922 D 233412 CDS NP_873558.1 33152205 1491010 861222..861674 1 NC_002940.2 hypothetical protein 861674 1491010 HD1080 Haemophilus ducreyi 35000HP hypothetical protein NP_873558.1 861222 D 233412 CDS NP_873559.1 33152206 1491011 861728..862948 1 NC_002940.2 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 862948 iscS 1491011 iscS Haemophilus ducreyi 35000HP cysteine desulfurase NP_873559.1 861728 D 233412 CDS NP_873560.1 33152207 1491012 862996..863379 1 NC_002940.2 scaffold protein 863379 iscU 1491012 iscU Haemophilus ducreyi 35000HP scaffold protein NP_873560.1 862996 D 233412 CDS NP_873561.1 33152208 1491013 863513..863836 1 NC_002940.2 hesB family protein 863836 1491013 HD1084 Haemophilus ducreyi 35000HP hesB family protein NP_873561.1 863513 D 233412 CDS NP_873562.1 33152209 1491014 863845..864366 1 NC_002940.2 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 864366 hscB 1491014 hscB Haemophilus ducreyi 35000HP co-chaperone HscB NP_873562.1 863845 D 233412 CDS NP_873563.1 33152210 1491015 864411..865043 1 NC_002940.2 hypothetical protein 865043 1491015 HD1086 Haemophilus ducreyi 35000HP hypothetical protein NP_873563.1 864411 D 233412 CDS NP_873564.1 33152211 1491016 865095..866948 1 NC_002940.2 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 866948 hscA 1491016 hscA Haemophilus ducreyi 35000HP chaperone protein HscA NP_873564.1 865095 D 233412 CDS NP_873565.1 33152212 1491017 866960..867301 1 NC_002940.2 ferredoxin 867301 fdx2 1491017 fdx2 Haemophilus ducreyi 35000HP ferredoxin NP_873565.1 866960 D 233412 CDS NP_873566.1 33152213 1491018 867346..867495 1 NC_002940.2 hypothetical protein 867495 1491018 HD1089 Haemophilus ducreyi 35000HP hypothetical protein NP_873566.1 867346 D 233412 CDS NP_873567.1 33152214 1491019 complement(867534..868343) 1 NC_002940.2 glycosyl transferase family protein 868343 1491019 HD1090 Haemophilus ducreyi 35000HP glycosyl transferase family protein NP_873567.1 867534 R 233412 CDS NP_873568.1 33152215 1491020 complement(868356..869594) 1 NC_002940.2 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 869594 cca 1491020 cca Haemophilus ducreyi 35000HP multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase NP_873568.1 868356 R 233412 CDS NP_873569.1 33152216 1491021 complement(869698..870207) 1 NC_002940.2 peptidyl-prolyl cis-trans isomerase B 870207 ppiB 1491021 ppiB Haemophilus ducreyi 35000HP peptidyl-prolyl cis-trans isomerase B NP_873569.1 869698 R 233412 CDS NP_873570.1 33152217 1491022 870350..871729 1 NC_002940.2 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 871729 cysS 1491022 cysS Haemophilus ducreyi 35000HP cysteinyl-tRNA synthetase NP_873570.1 870350 D 233412 CDS NP_873571.1 33152218 1491023 871818..874130 1 NC_002940.2 outer membrane serine protease 874130 1491023 HD1094 Haemophilus ducreyi 35000HP outer membrane serine protease NP_873571.1 871818 D 233412 CDS NP_873572.1 33152219 1491024 874155..874562 1 NC_002940.2 hypothetical protein 874562 1491024 HD1095 Haemophilus ducreyi 35000HP hypothetical protein NP_873572.1 874155 D 233412 CDS NP_873573.1 33152220 1491025 complement(874715..875104) 1 NC_002940.2 hypothetical protein 875104 1491025 HD1096 Haemophilus ducreyi 35000HP hypothetical protein NP_873573.1 874715 R 233412 CDS NP_873574.1 33152221 1491026 complement(875184..875300) 1 NC_002940.2 hypothetical protein 875300 1491026 HD1097 Haemophilus ducreyi 35000HP hypothetical protein NP_873574.1 875184 R 233412 CDS NP_873575.1 33152222 1491027 875420..876454 1 NC_002940.2 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding protein 876454 metN 1491027 metN Haemophilus ducreyi 35000HP DL-methionine transporter ATP-binding protein NP_873575.1 875420 D 233412 CDS NP_873576.1 33152223 1491028 876444..877121 1 NC_002940.2 D-methionine transport system permease protein MetI 877121 metI 1491028 metI Haemophilus ducreyi 35000HP D-methionine transport system permease protein MetI NP_873576.1 876444 D 233412 CDS NP_873577.1 33152224 1491029 877171..877983 1 NC_002940.2 hypothetical protein 877983 hlpA 1491029 hlpA Haemophilus ducreyi 35000HP hypothetical protein NP_873577.1 877171 D 233412 CDS NP_873578.1 33152225 1491030 complement(878056..878784) 1 NC_002940.2 catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position; 3-deoxy-D-manno-octulosonic-acid kinase 878784 kdkA 1491030 kdkA Haemophilus ducreyi 35000HP 3-deoxy-D-manno-octulosonic-acid kinase NP_873578.1 878056 R 233412 CDS NP_873579.1 33152226 1491031 complement(878759..878899) 1 NC_002940.2 hypothetical protein 878899 1491031 HD1102 Haemophilus ducreyi 35000HP hypothetical protein NP_873579.1 878759 R 233412 CDS NP_873580.1 33152227 1491032 878892..879548 1 NC_002940.2 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 879548 folE 1491032 folE Haemophilus ducreyi 35000HP GTP cyclohydrolase I NP_873580.1 878892 D 233412 CDS NP_873581.1 33152228 1491033 879647..880432 1 NC_002940.2 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 880432 truA 1491033 truA Haemophilus ducreyi 35000HP tRNA pseudouridine synthase A NP_873581.1 879647 D 233412 CDS NP_873582.1 33152229 1491034 complement(880491..880808) 1 NC_002940.2 hypothetical protein 880808 1491034 HD1105 Haemophilus ducreyi 35000HP hypothetical protein NP_873582.1 880491 R 233412 CDS NP_873583.1 33152230 1491035 880973..881911 1 NC_002940.2 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 881911 lpxL 1491035 lpxL Haemophilus ducreyi 35000HP lipid A biosynthesis lauroyl acyltransferase NP_873583.1 880973 D 233412 CDS NP_873584.1 33152231 1491036 882025..882918 1 NC_002940.2 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 882918 dapA 1491036 dapA Haemophilus ducreyi 35000HP dihydrodipicolinate synthase NP_873584.1 882025 D 233412 CDS NP_873585.1 33152232 1491039 883385..884248 1 NC_002940.2 bifunctional; methylenetetrahydrofolate dehydrogenase; methenyltetrahydrofolate cyclohydrolase 884248 folD 1491039 folD Haemophilus ducreyi 35000HP methenyltetrahydrofolate cyclohydrolase NP_873585.1 883385 D 233412 CDS NP_873586.1 33152233 1491040 884370..885911 1 NC_002940.2 oxalate/formate antiporter 885911 1491040 HD1109 Haemophilus ducreyi 35000HP oxalate/formate antiporter NP_873586.1 884370 D 233412 CDS NP_873587.1 33152234 1491041 complement(885961..886878) 1 NC_002940.2 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 886878 fdhE 1491041 fdhE Haemophilus ducreyi 35000HP formate dehydrogenase accessory protein FdhE NP_873587.1 885961 R 233412 CDS NP_873588.1 33152235 1491042 complement(886978..887652) 1 NC_002940.2 formate dehydrogenase, gamma subunit; cytochrome B556 subunit 887652 fdnI 1491042 fdnI Haemophilus ducreyi 35000HP cytochrome B556 subunit NP_873588.1 886978 R 233412 CDS NP_873589.1 33152236 1491043 complement(887645..887761) 1 NC_002940.2 formate dehydrogenase, iron-sulfur subunit, beta subunit 887761 1491043 HD1112 Haemophilus ducreyi 35000HP formate dehydrogenase, iron-sulfur subunit, beta subunit NP_873589.1 887645 R 233412 CDS NP_873590.1 33152237 1491044 887771..888442 1 NC_002940.2 formate dehydrogenase formation protein 888442 fdhD 1491044 fdhD Haemophilus ducreyi 35000HP formate dehydrogenase formation protein NP_873590.1 887771 D 233412 CDS NP_873591.1 33152238 1491045 complement(888520..889155) 1 NC_002940.2 endonuclease III, DNA (apurinic or apyrimidinic site) lyase 889155 nth 1491045 nth Haemophilus ducreyi 35000HP endonuclease III, DNA (apurinic or apyrimidinic site) lyase NP_873591.1 888520 R 233412 CDS NP_873592.1 33152239 1491046 complement(889185..889967) 1 NC_002940.2 hypothetical protein 889967 1491046 HD1117 Haemophilus ducreyi 35000HP hypothetical protein NP_873592.1 889185 R 233412 CDS NP_873593.1 33152240 1491047 890053..890538 1 NC_002940.2 dihydrofolate reductase 890538 folA 1491047 folA Haemophilus ducreyi 35000HP dihydrofolate reductase NP_873593.1 890053 D 233412 CDS NP_873594.1 33152241 1491048 complement(890516..890614) 1 NC_002940.2 hypothetical protein 890614 1491048 HD1119 Haemophilus ducreyi 35000HP hypothetical protein NP_873594.1 890516 R 233412 CDS NP_873595.1 33152242 1491049 890660..890875 1 NC_002940.2 hypothetical protein 890875 1491049 HD1120 Haemophilus ducreyi 35000HP hypothetical protein NP_873595.1 890660 D 233412 CDS NP_873596.1 33152243 1491050 complement(890942..892321) 1 NC_002940.2 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 892321 radA 1491050 radA Haemophilus ducreyi 35000HP DNA repair protein RadA NP_873596.1 890942 R 233412 CDS NP_873597.1 33152244 1491051 892515..892964 1 NC_002940.2 prepilin peptidase dependent protein D 892964 1491051 HD1123 Haemophilus ducreyi 35000HP prepilin peptidase dependent protein D NP_873597.1 892515 D 233412 CDS NP_873598.1 33152245 1491052 892976..894370 1 NC_002940.2 protein transport protein HofB, pili/fimbriae biogenesis protein 894370 hofB 1491052 hofB Haemophilus ducreyi 35000HP protein transport protein HofB, pili/fimbriae biogenesis protein NP_873598.1 892976 D 233412 CDS NP_873599.1 33152246 1491053 894354..895547 1 NC_002940.2 protein transport protein HofC; pili/fimbriae biogenesis protein 895547 hofC 1491053 hofC Haemophilus ducreyi 35000HP pili/fimbriae biogenesis protein NP_873599.1 894354 D 233412 CDS NP_873600.1 33152247 1491054 895685..896239 1 NC_002940.2 hypothetical protein 896239 1491054 HD1126 Haemophilus ducreyi 35000HP hypothetical protein NP_873600.1 895685 D 233412 CDS NP_873601.1 33152248 1491055 896257..896874 1 NC_002940.2 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 896874 coaE 1491055 coaE Haemophilus ducreyi 35000HP dephospho-CoA kinase NP_873601.1 896257 D 233412 CDS NP_873602.1 33152249 1491056 896877..897065 1 NC_002940.2 hypothetical protein 897065 1491056 HD1129 Haemophilus ducreyi 35000HP hypothetical protein NP_873602.1 896877 D 233412 CDS NP_873603.1 33152250 1491057 complement(897099..898124) 1 NC_002940.2 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 898124 holA 1491057 holA Haemophilus ducreyi 35000HP DNA polymerase III subunit delta NP_873603.1 897099 R 233412 CDS NP_873604.1 33152251 1491058 complement(898130..898627) 1 NC_002940.2 rare lipoprotein B 898627 rlpB 1491058 rlpB Haemophilus ducreyi 35000HP rare lipoprotein B NP_873604.1 898130 R 233412 CDS NP_873605.1 33152252 1491059 complement(898676..901261) 1 NC_002940.2 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 901261 leuS 1491059 leuS Haemophilus ducreyi 35000HP leucyl-tRNA synthetase NP_873605.1 898676 R 233412 CDS NP_873606.1 33152253 1491060 complement(901412..902719) 1 NC_002940.2 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 902719 serS 1491060 serS Haemophilus ducreyi 35000HP seryl-tRNA synthetase NP_873606.1 901412 R 233412 CDS NP_873607.1 33152254 1491061 complement(902777..903259) 1 NC_002940.2 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 903259 smpB 1491061 smpB Haemophilus ducreyi 35000HP SsrA-binding protein NP_873607.1 902777 R 233412 CDS NP_873608.1 33152255 1491062 complement(903365..904774) 1 NC_002940.2 hypothetical protein 904774 1491062 HD1136 Haemophilus ducreyi 35000HP hypothetical protein NP_873608.1 903365 R 233412 CDS NP_873609.1 33152256 1491063 complement(904828..904986) 1 NC_002940.2 hypothetical protein 904986 1491063 HD1137 Haemophilus ducreyi 35000HP hypothetical protein NP_873609.1 904828 R 233412 CDS NP_873610.1 33152257 1491064 complement(904995..905726) 1 NC_002940.2 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 905726 1491064 HD1138 Haemophilus ducreyi 35000HP tRNA pseudouridine synthase C NP_873610.1 904995 R 233412 CDS NP_873611.1 33152258 1491065 complement(905726..906079) 1 NC_002940.2 hypothetical protein 906079 1491065 HD1139 Haemophilus ducreyi 35000HP hypothetical protein NP_873611.1 905726 R 233412 CDS NP_873612.1 33152259 1491066 906163..906294 1 NC_002940.2 hypothetical protein 906294 1491066 HD1140 Haemophilus ducreyi 35000HP hypothetical protein NP_873612.1 906163 D 233412 CDS NP_873613.1 33152260 1491067 906346..908349 1 NC_002940.2 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 908349 mnmC 1491067 mnmC Haemophilus ducreyi 35000HP 5-methylaminomethyl-2-thiouridine methyltransferase NP_873613.1 906346 D 233412 CDS NP_873614.1 33152261 1491068 complement(908408..909787) 1 NC_002940.2 L-serine dehydratase 909787 sdaA 1491068 sdaA Haemophilus ducreyi 35000HP L-serine dehydratase NP_873614.1 908408 R 233412 CDS NP_873615.1 33152262 1491069 complement(909898..911124) 1 NC_002940.2 serine transporter 911124 sdaC 1491069 sdaC Haemophilus ducreyi 35000HP serine transporter NP_873615.1 909898 R 233412 CDS NP_873616.1 33152263 1491070 complement(911305..912822) 1 NC_002940.2 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 912822 lnt 1491070 lnt Haemophilus ducreyi 35000HP apolipoprotein N-acyltransferase NP_873616.1 911305 R 233412 CDS NP_873617.1 33152264 1491071 complement(912883..913773) 1 NC_002940.2 magnesium and cobalt efflux protein 913773 corC 1491071 corC Haemophilus ducreyi 35000HP magnesium and cobalt efflux protein NP_873617.1 912883 R 233412 CDS NP_873618.1 33152265 1491072 914141..914923 1 NC_002940.2 glycerol uptake facilitator protein 914923 glpF 1491072 glpF Haemophilus ducreyi 35000HP glycerol uptake facilitator protein NP_873618.1 914141 D 233412 CDS NP_873619.1 33152266 1491074 complement(916573..918981) 1 NC_002940.2 ATP-dependent protease LA 918981 lon 1491074 lon Haemophilus ducreyi 35000HP ATP-dependent protease LA NP_873619.1 916573 R 233412 CDS NP_873620.1 33152267 1491075 complement(919175..920611) 1 NC_002940.2 glycerol 3-phosphate transporter; G-3-P permease 920611 glpT 1491075 glpT Haemophilus ducreyi 35000HP G-3-P permease NP_873620.1 919175 R 233412 CDS NP_873621.1 33152268 1491076 complement(920631..920732) 1 NC_002940.2 hypothetical protein 920732 1491076 HD1151 Haemophilus ducreyi 35000HP hypothetical protein NP_873621.1 920631 R 233412 CDS NP_873622.1 33152269 1491078 921945..923714 1 NC_002940.2 large supernatant protein exporter 923714 lspB 1491078 lspB Haemophilus ducreyi 35000HP large supernatant protein exporter NP_873622.1 921945 D 233412 CDS NP_873623.1 33152270 1491079 923760..938519 1 NC_002940.2 large supernatant protein 2 938519 lspA2 1491079 lspA2 Haemophilus ducreyi 35000HP large supernatant protein 2 NP_873623.1 923760 D 233412 CDS NP_873624.1 33152271 1491080 938752..940434 1 NC_002940.2 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 940434 glpA 1491080 glpA Haemophilus ducreyi 35000HP sn-glycerol-3-phosphate dehydrogenase subunit A NP_873624.1 938752 D 233412 CDS NP_873625.1 33152272 1491081 940424..941704 1 NC_002940.2 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 941704 glpB 1491081 glpB Haemophilus ducreyi 35000HP anaerobic glycerol-3-phosphate dehydrogenase subunit B NP_873625.1 940424 D 233412 CDS NP_873626.1 33152273 1491082 941701..942975 1 NC_002940.2 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 942975 glpC 1491082 glpC Haemophilus ducreyi 35000HP sn-glycerol-3-phosphate dehydrogenase subunit C NP_873626.1 941701 D 233412 CDS NP_873627.1 33152274 1491083 943332..944438 1 NC_002940.2 riboflavin-specific deaminase; riboflavin biosynthesis protein RibD 944438 ribD 1491083 ribD Haemophilus ducreyi 35000HP riboflavin biosynthesis protein RibD NP_873627.1 943332 D 233412 CDS NP_873628.1 33152275 1491084 944453..945100 1 NC_002940.2 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 945100 ribE 1491084 ribE Haemophilus ducreyi 35000HP riboflavin synthase subunit alpha NP_873628.1 944453 D 233412 CDS NP_873629.1 33152276 1491085 945156..946361 1 NC_002940.2 Includes: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase; riboflavin biosynthesis protein ribA 946361 ribAB 1491085 ribAB Haemophilus ducreyi 35000HP riboflavin biosynthesis protein ribA NP_873629.1 945156 D 233412 CDS NP_873630.1 33152277 1491086 946471..946932 1 NC_002940.2 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 946932 ribH 1491086 ribH Haemophilus ducreyi 35000HP 6,7-dimethyl-8-ribityllumazine synthase NP_873630.1 946471 D 233412 CDS NP_873631.1 33152278 1491087 complement(946950..947042) 1 NC_002940.2 hypothetical protein 947042 1491087 HD1166 Haemophilus ducreyi 35000HP hypothetical protein NP_873631.1 946950 R 233412 CDS NP_873632.1 33152279 1491088 complement(947020..947508) 1 NC_002940.2 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 947508 greB 1491088 greB Haemophilus ducreyi 35000HP transcription elongation factor GreB NP_873632.1 947020 R 233412 CDS NP_873633.1 33152280 1491089 complement(947516..948451) 1 NC_002940.2 arabinose-5-phosphate isomerase 948451 kpsF 1491089 kpsF Haemophilus ducreyi 35000HP arabinose-5-phosphate isomerase NP_873633.1 947516 R 233412 CDS NP_873634.1 33152281 1491090 complement(948543..949853) 1 NC_002940.2 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase 949853 pepB 1491090 pepB Haemophilus ducreyi 35000HP aminopeptidase NP_873634.1 948543 R 233412 CDS NP_873635.1 33152282 1491091 complement(949960..950790) 1 NC_002940.2 outer membrane protein P4 950790 ompP4 1491091 ompP4 Haemophilus ducreyi 35000HP outer membrane protein P4 NP_873635.1 949960 R 233412 CDS NP_873636.1 33152283 1491092 complement(950986..951801) 1 NC_002940.2 haloacid dehalogenase-like hydrolase 951801 1491092 HD1171 Haemophilus ducreyi 35000HP haloacid dehalogenase-like hydrolase NP_873636.1 950986 R 233412 CDS NP_873637.1 33152284 1491093 952698..953276 1 NC_002940.2 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 953276 rpoE 1491093 rpoE Haemophilus ducreyi 35000HP RNA polymerase sigma factor RpoE NP_873637.1 952698 D 233412 CDS NP_873638.1 33152285 1491094 953295..953906 1 NC_002940.2 sigma-E factor negative regulatory protein 953906 rseA 1491094 rseA Haemophilus ducreyi 35000HP sigma-E factor negative regulatory protein NP_873638.1 953295 D 233412 CDS NP_873639.1 33152286 1491095 954084..954512 1 NC_002940.2 sigma-E factor regulatory protein 954512 rseC 1491095 rseC Haemophilus ducreyi 35000HP sigma-E factor regulatory protein NP_873639.1 954084 D 233412 CDS NP_873640.1 33152287 1491097 956253..956879 1 NC_002940.2 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 956879 upp 1491097 upp Haemophilus ducreyi 35000HP uracil phosphoribosyltransferase NP_873640.1 956253 D 233412 CDS NP_873641.1 33152288 1491098 complement(956945..957814) 1 NC_002940.2 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 957814 ksgA 1491098 ksgA Haemophilus ducreyi 35000HP dimethyladenosine transferase NP_873641.1 956945 R 233412 CDS NP_873642.1 33152289 1491099 complement(957879..958832) 1 NC_002940.2 survival protein SurA; peptidyl-prolyl cis-trans isomerase 958832 surA 1491099 surA Haemophilus ducreyi 35000HP peptidyl-prolyl cis-trans isomerase NP_873642.1 957879 R 233412 CDS NP_873643.1 33152290 1491100 complement(958921..959460) 1 NC_002940.2 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 959460 pyrR 1491100 pyrR Haemophilus ducreyi 35000HP bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase NP_873643.1 958921 R 233412 CDS NP_873644.1 33152291 1491101 complement(959473..960903) 1 NC_002940.2 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 960903 waaE 1491101 waaE Haemophilus ducreyi 35000HP bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase NP_873644.1 959473 R 233412 CDS NP_873645.1 33152292 1491102 complement(960963..962495) 1 NC_002940.2 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 962495 engA 1491102 engA Haemophilus ducreyi 35000HP GTP-binding protein EngA NP_873645.1 960963 R 233412 CDS NP_873646.1 33152293 1491103 962822..965029 1 NC_002940.2 ppGpp synthetase I; GTP pyrophosphokinase 965029 relA 1491103 relA Haemophilus ducreyi 35000HP GTP pyrophosphokinase NP_873646.1 962822 D 233412 CDS NP_873647.1 33152294 1491104 965108..966298 1 NC_002940.2 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 966298 dxr 1491104 dxr Haemophilus ducreyi 35000HP 1-deoxy-D-xylulose 5-phosphate reductoisomerase NP_873647.1 965108 D 233412 CDS NP_873648.1 33152295 1491105 complement(966368..967162) 1 NC_002940.2 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 967162 lpxA 1491105 lpxA Haemophilus ducreyi 35000HP UDP-N-acetylglucosamine acyltransferase NP_873648.1 966368 R 233412 CDS NP_873649.1 33152296 1491106 complement(967204..967668) 1 NC_002940.2 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 967668 fabZ 1491106 fabZ Haemophilus ducreyi 35000HP (3R)-hydroxymyristoyl-ACP dehydratase NP_873649.1 967204 R 233412 CDS NP_873650.1 33152297 1491107 complement(967735..968760) 1 NC_002940.2 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 968760 lpxD 1491107 lpxD Haemophilus ducreyi 35000HP UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase NP_873650.1 967735 R 233412 CDS NP_873651.1 33152298 1491108 complement(968760..969539) 1 NC_002940.2 hypothetical protein 969539 1491108 HD1190 Haemophilus ducreyi 35000HP hypothetical protein NP_873651.1 968760 R 233412 CDS NP_873652.1 33152299 1491109 complement(969641..972022) 1 NC_002940.2 outer membrane protein D-15 972022 D15 1491109 D15 Haemophilus ducreyi 35000HP outer membrane protein D-15 NP_873652.1 969641 R 233412 CDS NP_873653.1 33152300 1491110 complement(972071..973384) 1 NC_002940.2 protease EcfE 973384 ecfE 1491110 ecfE Haemophilus ducreyi 35000HP protease EcfE NP_873653.1 972071 R 233412 CDS NP_873654.1 33152301 1491111 complement(973391..974260) 1 NC_002940.2 Phosphatidate cytidylyltransferase; CDP-diglyceride pyrophosphorylase 974260 cdsA 1491111 cdsA Haemophilus ducreyi 35000HP CDP-diglyceride pyrophosphorylase NP_873654.1 973391 R 233412 CDS NP_873655.1 33152302 1491112 complement(974277..975005) 1 NC_002940.2 undecaprenyl pyrophosphate synthetase; UPP synthase 975005 uppS 1491112 uppS Haemophilus ducreyi 35000HP UPP synthase NP_873655.1 974277 R 233412 CDS NP_873656.1 33152303 1491113 complement(975156..975863) 1 NC_002940.2 hydroxyacylglutathione hydrolase 975863 gloB 1491113 gloB Haemophilus ducreyi 35000HP hydroxyacylglutathione hydrolase NP_873656.1 975156 R 233412 CDS NP_873657.1 33152304 1491114 complement(975913..976641) 1 NC_002940.2 phosphatidylglycerophosphatase B 976641 pgpB 1491114 pgpB Haemophilus ducreyi 35000HP phosphatidylglycerophosphatase B NP_873657.1 975913 R 233412 CDS NP_873658.1 33152305 1491115 complement(976714..977028) 1 NC_002940.2 hypothetical protein 977028 1491115 HD1200 Haemophilus ducreyi 35000HP hypothetical protein NP_873658.1 976714 R 233412 CDS NP_873659.1 33152306 1491116 977139..977897 1 NC_002940.2 UDP-glucose--lipooligosaccharide beta 1-4 glucosyltransferase 977897 LgtF 1491116 LgtF Haemophilus ducreyi 35000HP UDP-glucose--lipooligosaccharide beta 1-4 glucosyltransferase NP_873659.1 977139 D 233412 CDS NP_873660.1 33152307 1491117 complement(977937..978971) 1 NC_002940.2 ADP-heptose--LPS heptosyltransferase III 978971 WaaQ 1491117 WaaQ Haemophilus ducreyi 35000HP ADP-heptose--LPS heptosyltransferase III NP_873660.1 977937 R 233412 CDS NP_873661.1 33152308 1491118 978977..979114 1 NC_002940.2 hypothetical protein 979114 1491118 HD1203 Haemophilus ducreyi 35000HP hypothetical protein NP_873661.1 978977 D 233412 CDS NP_873662.1 33152309 1491119 979180..980511 1 NC_002940.2 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 980511 argG 1491119 argG Haemophilus ducreyi 35000HP argininosuccinate synthase NP_873662.1 979180 D 233412 CDS NP_873663.1 33152310 1491120 980616..981257 1 NC_002940.2 hypothetical protein 981257 1491120 HD1205 Haemophilus ducreyi 35000HP hypothetical protein NP_873663.1 980616 D 233412 CDS NP_873664.1 33152311 1491121 981501..981962 1 NC_002940.2 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 981962 rnhA 1491121 rnhA Haemophilus ducreyi 35000HP ribonuclease H NP_873664.1 981501 D 233412 CDS NP_873665.1 33152312 1491122 complement(981988..982137) 1 NC_002940.2 hypothetical protein 982137 1491122 HD1207 Haemophilus ducreyi 35000HP hypothetical protein NP_873665.1 981988 R 233412 CDS NP_873666.1 33152313 1491123 982118..982630 1 NC_002940.2 colicin V production protein 982630 cvpA 1491123 cvpA Haemophilus ducreyi 35000HP colicin V production protein NP_873666.1 982118 D 233412 CDS NP_873667.1 33152314 1491125 complement(984290..984772) 1 NC_002940.2 hypothetical protein 984772 1491125 HD1211 Haemophilus ducreyi 35000HP hypothetical protein NP_873667.1 984290 R 233412 CDS NP_873668.1 33152315 1491126 complement(985049..985432) 1 NC_002940.2 small protein A 985432 smpA 1491126 smpA Haemophilus ducreyi 35000HP small protein A NP_873668.1 985049 R 233412 CDS NP_873669.1 33152316 1491128 986581..986970 1 NC_002940.2 hypothetical protein 986970 1491128 HD1215 Haemophilus ducreyi 35000HP hypothetical protein NP_873669.1 986581 D 233412 CDS NP_873670.1 33152317 1491129 986995..987732 1 NC_002940.2 hypothetical protein 987732 1491129 HD1216 Haemophilus ducreyi 35000HP hypothetical protein NP_873670.1 986995 D 233412 CDS NP_873671.1 33152318 1491131 complement(987952..988296) 1 NC_002940.2 PliC; periplasmic lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 988296 1491131 HD1218 Haemophilus ducreyi 35000HP lysozyme inhibitor NP_873671.1 987952 R 233412 CDS NP_873672.1 33152319 1491132 complement(988501..989235) 1 NC_002940.2 hypothetical protein 989235 1491132 HD1219 Haemophilus ducreyi 35000HP hypothetical protein NP_873672.1 988501 R 233412 CDS NP_873673.1 33152320 1491133 complement(989280..990689) 1 NC_002940.2 iron-sulfur electron transport protein 990689 ykgF 1491133 ykgF Haemophilus ducreyi 35000HP iron-sulfur electron transport protein NP_873673.1 989280 R 233412 CDS NP_873674.1 33152321 1491134 complement(990704..991429) 1 NC_002940.2 dehydrogenase subunit 991429 ykgE 1491134 ykgE Haemophilus ducreyi 35000HP dehydrogenase subunit NP_873674.1 990704 R 233412 CDS NP_873675.1 33152322 1491137 992342..992713 1 NC_002940.2 hypothetical protein 992713 1491137 HD1225 Haemophilus ducreyi 35000HP hypothetical protein NP_873675.1 992342 D 233412 CDS NP_873676.1 33152323 1491138 993037..994770 1 NC_002940.2 integral membrane protein 994770 1491138 HD1227 Haemophilus ducreyi 35000HP integral membrane protein NP_873676.1 993037 D 233412 CDS NP_873677.1 33152324 1491139 complement(994843..995427) 1 NC_002940.2 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 995427 gmhA 1491139 gmhA Haemophilus ducreyi 35000HP phosphoheptose isomerase NP_873677.1 994843 R 233412 CDS NP_873678.1 33152325 1491140 995630..996781 1 NC_002940.2 transcriptional regulatory protein 996781 tyrR 1491140 tyrR Haemophilus ducreyi 35000HP transcriptional regulatory protein NP_873678.1 995630 D 233412 CDS NP_873679.1 33152326 1491141 996781..998463 1 NC_002940.2 peptide transport periplasmic protein SapA 998463 sapA 1491141 sapA Haemophilus ducreyi 35000HP peptide transport periplasmic protein SapA NP_873679.1 996781 D 233412 CDS NP_873680.1 33152327 1491142 998469..999431 1 NC_002940.2 peptide transport system permease SapB 999431 sapB 1491142 sapB Haemophilus ducreyi 35000HP peptide transport system permease SapB NP_873680.1 998469 D 233412 CDS NP_873681.1 33152328 1491143 999421..1000308 1 NC_002940.2 peptide transport system permease SapC 1000308 sapC 1491143 sapC Haemophilus ducreyi 35000HP peptide transport system permease SapC NP_873681.1 999421 D 233412 CDS NP_873682.1 33152329 1491144 1000324..1001361 1 NC_002940.2 peptide transport system ATP binding protein SapD 1001361 sapD 1491144 sapD Haemophilus ducreyi 35000HP peptide transport system ATP binding protein SapD NP_873682.1 1000324 D 233412 CDS NP_873683.1 33152330 1491145 1001515..1004403 1 NC_002940.2 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 1004403 polA 1491145 polA Haemophilus ducreyi 35000HP DNA polymerase I NP_873683.1 1001515 D 233412 CDS NP_873684.1 33152331 1491146 1004481..1005113 1 NC_002940.2 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1005113 lolA 1491146 lolA Haemophilus ducreyi 35000HP outer-membrane lipoprotein carrier protein NP_873684.1 1004481 D 233412 CDS NP_873685.1 33152332 1491147 1005195..1006112 1 NC_002940.2 ribosomal protein S6 modification protein 1006112 rimK 1491147 rimK Haemophilus ducreyi 35000HP ribosomal protein S6 modification protein NP_873685.1 1005195 D 233412 CDS NP_873686.1 33152333 1491148 complement(1006116..1006886) 1 NC_002940.2 hypothetical protein 1006886 1491148 HD1239 Haemophilus ducreyi 35000HP hypothetical protein NP_873686.1 1006116 R 233412 CDS NP_873687.1 33152334 1491149 1007088..1008104 1 NC_002940.2 citrate lyase synthetase; [citrate [pro-3S]-lyase] ligase 1008104 citC 1491149 citC Haemophilus ducreyi 35000HP [citrate [pro-3S]-lyase] ligase NP_873687.1 1007088 D 233412 CDS NP_873688.1 33152335 1491150 1008148..1008450 1 NC_002940.2 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 1008450 citD 1491150 citD Haemophilus ducreyi 35000HP citrate lyase subunit gamma NP_873688.1 1008148 D 233412 CDS NP_873689.1 33152336 1491151 1008447..1009334 1 NC_002940.2 citryl-CoA lyase subunit; citrate lyase beta chain 1009334 citE 1491151 citE Haemophilus ducreyi 35000HP citrate lyase beta chain NP_873689.1 1008447 D 233412 CDS NP_873690.1 33152337 1491152 1009346..1010848 1 NC_002940.2 citrate lyase alpha chain; citrate CoA-transferase subunit 1010848 citF 1491152 citF Haemophilus ducreyi 35000HP citrate CoA-transferase subunit NP_873690.1 1009346 D 233412 CDS NP_873691.1 33152338 1491153 1010902..1012317 1 NC_002940.2 Includes: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; 2-(5''- triphosphoribosyl) -3'-dephosphocoenzyme-A synthase; CitXG protein 1012317 citG 1491153 citG Haemophilus ducreyi 35000HP CitXG protein NP_873691.1 1010902 D 233412 CDS NP_873692.1 33152339 1491154 1012326..1013774 1 NC_002940.2 oxoglutarate/malate translocator 1013774 1491154 HD1246 Haemophilus ducreyi 35000HP oxoglutarate/malate translocator NP_873692.1 1012326 D 233412 CDS NP_873693.1 33152340 1491155 1014008..1015276 1 NC_002940.2 malate oxidoreductase (NAD) 1015276 maeA 1491155 maeA Haemophilus ducreyi 35000HP malate oxidoreductase (NAD) NP_873693.1 1014008 D 233412 CDS NP_873694.1 33152341 1491156 complement(1015281..1015376) 1 NC_002940.2 hypothetical protein 1015376 1491156 HD1248 Haemophilus ducreyi 35000HP hypothetical protein NP_873694.1 1015281 R 233412 CDS NP_873695.1 33152342 1491157 1015461..1015748 1 NC_002940.2 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1015748 rplY 1491157 rplY Haemophilus ducreyi 35000HP 50S ribosomal protein L25 NP_873695.1 1015461 D 233412 CDS NP_873696.1 33152343 1491159 complement(1017475..1017579) 1 NC_002940.2 hypothetical protein 1017579 1491159 HD1252 Haemophilus ducreyi 35000HP hypothetical protein NP_873696.1 1017475 R 233412 CDS NP_873697.1 33152344 1491160 complement(1017558..1017917) 1 NC_002940.2 diacylglycerol kinase 1017917 dgkA 1491160 dgkA Haemophilus ducreyi 35000HP diacylglycerol kinase NP_873697.1 1017558 R 233412 CDS NP_873698.1 33152345 1491161 1018150..1019361 1 NC_002940.2 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 1019361 1491161 HD1254 Haemophilus ducreyi 35000HP serine/threonine transporter SstT NP_873698.1 1018150 D 233412 CDS NP_873699.1 33152346 1491162 1019499..1021787 1 NC_002940.2 recombination protein 2 1021787 rec2 1491162 rec2 Haemophilus ducreyi 35000HP recombination protein 2 NP_873699.1 1019499 D 233412 CDS NP_873700.1 33152347 1491163 complement(1021839..1022924) 1 NC_002940.2 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1022924 queA 1491163 queA Haemophilus ducreyi 35000HP S-adenosylmethionine--tRNA ribosyltransferase-isomerase NP_873700.1 1021839 R 233412 CDS NP_873701.1 33152348 1491164 complement(1023004..1024059) 1 NC_002940.2 permease 1024059 perM 1491164 perM Haemophilus ducreyi 35000HP permease NP_873701.1 1023004 R 233412 CDS NP_873702.1 33152349 1491167 complement(1025214..1026026) 1 NC_002940.2 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 1026026 apaH 1491167 apaH Haemophilus ducreyi 35000HP diadenosine tetraphosphatase NP_873702.1 1025214 R 233412 CDS NP_873703.1 33152350 1491168 complement(1026086..1028065) 1 NC_002940.2 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1028065 rnb 1491168 rnb Haemophilus ducreyi 35000HP exoribonuclease II NP_873703.1 1026086 R 233412 CDS NP_873704.1 33152351 1491169 complement(1028254..1029042) 1 NC_002940.2 enoyl-[acyl-carrier-protein] reductase [NADH]; NADH- dependent enoyl-ACP reductase 1029042 fabI 1491169 fabI Haemophilus ducreyi 35000HP NADH- dependent enoyl-ACP reductase NP_873704.1 1028254 R 233412 CDS NP_873705.1 33152352 1491170 complement(1029213..1029947) 1 NC_002940.2 SAM-dependent methyltransferase 1029947 1491170 HD1267 Haemophilus ducreyi 35000HP SAM-dependent methyltransferase NP_873705.1 1029213 R 233412 CDS NP_873706.1 33152353 1491171 complement(1029947..1030738) 1 NC_002940.2 esterase/lipase 1030738 1491171 HD1268 Haemophilus ducreyi 35000HP esterase/lipase NP_873706.1 1029947 R 233412 CDS NP_873707.1 33152354 1491172 1030863..1031423 1 NC_002940.2 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 1031423 seqA 1491172 seqA Haemophilus ducreyi 35000HP replication initiation regulator SeqA NP_873707.1 1030863 D 233412 CDS NP_873708.1 33152355 1491173 1031424..1032842 1 NC_002940.2 O-succinylbenzoic acid--CoA ligase 1032842 menE 1491173 menE Haemophilus ducreyi 35000HP O-succinylbenzoic acid--CoA ligase NP_873708.1 1031424 D 233412 CDS NP_873709.1 33152356 1491175 1036193..1037275 1 NC_002940.2 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1037275 aroC 1491175 aroC Haemophilus ducreyi 35000HP chorismate synthase NP_873709.1 1036193 D 233412 CDS NP_873710.1 33152357 1491176 1037327..1038157 1 NC_002940.2 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 1038157 mepA 1491176 mepA Haemophilus ducreyi 35000HP penicillin-insensitive murein endopeptidase NP_873710.1 1037327 D 233412 CDS NP_873711.1 33152358 1491177 1038166..1040085 1 NC_002940.2 decatenates replicating daughter chromosomes; DNA topoisomerase III 1040085 topB2 1491177 topB2 Haemophilus ducreyi 35000HP DNA topoisomerase III NP_873711.1 1038166 D 233412 CDS NP_873712.1 33152359 1491178 1040214..1040543 1 NC_002940.2 preprotein translocase subunit SecG 1040543 secG 1491178 secG Haemophilus ducreyi 35000HP preprotein translocase subunit SecG NP_873712.1 1040214 D 233412 CDS NP_873713.1 33152360 1491180 1040787..1041965 1 NC_002940.2 serine protease 1041965 1491180 HD1278 Haemophilus ducreyi 35000HP serine protease NP_873713.1 1040787 D 233412 CDS NP_873714.1 33152361 1491181 1041966..1043861 1 NC_002940.2 serine protease-like protein 1043861 1491181 HD1280 Haemophilus ducreyi 35000HP serine protease-like protein NP_873714.1 1041966 D 233412 CDS NP_873715.1 33152362 1491182 complement(1043954..1045624) 1 NC_002940.2 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1045624 fhs 1491182 fhs Haemophilus ducreyi 35000HP formate--tetrahydrofolate ligase NP_873715.1 1043954 R 233412 CDS NP_873716.1 33152363 1491183 1045600..1045710 1 NC_002940.2 hypothetical protein 1045710 1491183 HD1283 Haemophilus ducreyi 35000HP hypothetical protein NP_873716.1 1045600 D 233412 CDS NP_873717.1 33152364 1491184 1045743..1046186 1 NC_002940.2 hypothetical protein 1046186 1491184 HD1284 Haemophilus ducreyi 35000HP hypothetical protein NP_873717.1 1045743 D 233412 CDS NP_873718.1 33152365 1491185 complement(1046317..1046847) 1 NC_002940.2 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1046847 ssb 1491185 ssb Haemophilus ducreyi 35000HP single-stranded DNA-binding protein NP_873718.1 1046317 R 233412 CDS NP_873719.1 33152366 1491186 1046994..1049822 1 NC_002940.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1049822 uvrA 1491186 uvrA Haemophilus ducreyi 35000HP excinuclease ABC subunit A NP_873719.1 1046994 D 233412 CDS NP_873720.1 33152367 1491187 1049843..1051762 1 NC_002940.2 ATP-dependent helicase 1051762 1491187 HD1287 Haemophilus ducreyi 35000HP ATP-dependent helicase NP_873720.1 1049843 D 233412 CDS NP_873721.1 33152368 1491188 1051931..1052173 1 NC_002940.2 hypothetical protein 1052173 1491188 HD1288 Haemophilus ducreyi 35000HP hypothetical protein NP_873721.1 1051931 D 233412 CDS NP_873722.1 33152369 1491189 1052194..1052886 1 NC_002940.2 hypothetical protein 1052886 1491189 HD1289 Haemophilus ducreyi 35000HP hypothetical protein NP_873722.1 1052194 D 233412 CDS NP_873723.1 33152370 1491190 complement(1053040..1053432) 1 NC_002940.2 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1053432 msrB 1491190 msrB Haemophilus ducreyi 35000HP methionine sulfoxide reductase B NP_873723.1 1053040 R 233412 CDS NP_873724.1 33152371 1491191 1053689..1054693 1 NC_002940.2 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 1054693 gapA 1491191 gapA Haemophilus ducreyi 35000HP glyceraldehyde-3-phosphate dehydrogenase NP_873724.1 1053689 D 233412 CDS NP_873725.1 33152372 1491192 1054896..1055948 1 NC_002940.2 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 1055948 mreB 1491192 mreB Haemophilus ducreyi 35000HP rod shape-determining protein MreB NP_873725.1 1054896 D 233412 CDS NP_873726.1 33152373 1491193 1056044..1057105 1 NC_002940.2 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 1057105 mreC 1491193 mreC Haemophilus ducreyi 35000HP rod shape-determining protein MreC NP_873726.1 1056044 D 233412 CDS NP_873727.1 33152374 1491194 1057105..1057593 1 NC_002940.2 rod shape-determining protein MreD 1057593 mreD 1491194 mreD Haemophilus ducreyi 35000HP rod shape-determining protein MreD NP_873727.1 1057105 D 233412 CDS NP_873728.1 33152375 1491195 1057641..1058981 1 NC_002940.2 recombination factor protein RarA 1058981 1491195 HD1296 Haemophilus ducreyi 35000HP recombination factor protein RarA NP_873728.1 1057641 D 233412 CDS NP_873729.1 33152376 1491196 1059017..1059802 1 NC_002940.2 high-affinity zinc uptake system membrane protein 1059802 znuB 1491196 znuB Haemophilus ducreyi 35000HP high-affinity zinc uptake system membrane protein NP_873729.1 1059017 D 233412 CDS NP_873730.1 33152377 1491197 complement(1059964..1061652) 1 NC_002940.2 tight adherence protein G 1061652 tadG 1491197 tadG Haemophilus ducreyi 35000HP tight adherence protein G NP_873730.1 1059964 R 233412 CDS NP_873731.1 33152378 1491198 complement(1061686..1062297) 1 NC_002940.2 tight adherence protein F 1062297 tadF 1491198 tadF Haemophilus ducreyi 35000HP tight adherence protein F NP_873731.1 1061686 R 233412 CDS NP_873732.1 33152379 1491199 complement(1062266..1062772) 1 NC_002940.2 tight adherence protein E 1062772 tadE 1491199 tadE Haemophilus ducreyi 35000HP tight adherence protein E NP_873732.1 1062266 R 233412 CDS NP_873733.1 33152380 1491200 complement(1062775..1063527) 1 NC_002940.2 tight adherence protein D 1063527 tadD 1491200 tadD Haemophilus ducreyi 35000HP tight adherence protein D NP_873733.1 1062775 R 233412 CDS NP_873734.1 33152381 1491201 complement(1063517..1064389) 1 NC_002940.2 tight adherence protein C 1064389 tadC 1491201 tadC Haemophilus ducreyi 35000HP tight adherence protein C NP_873734.1 1063517 R 233412 CDS NP_873735.1 33152382 1491202 complement(1064362..1065249) 1 NC_002940.2 tight adherence protein B 1065249 tadB 1491202 tadB Haemophilus ducreyi 35000HP tight adherence protein B NP_873735.1 1064362 R 233412 CDS NP_873736.1 33152383 1491203 complement(1065246..1066529) 1 NC_002940.2 tight adherence protein A 1066529 tadA 1491203 tadA Haemophilus ducreyi 35000HP tight adherence protein A NP_873736.1 1065246 R 233412 CDS NP_873737.1 33152384 1491204 complement(1066538..1067659) 1 NC_002940.2 flp operon protein D 1067659 1491204 HD1305 Haemophilus ducreyi 35000HP flp operon protein D NP_873737.1 1066538 R 233412 CDS NP_873738.1 33152385 1491205 complement(1067682..1068173) 1 NC_002940.2 rough colony protein B 1068173 rcpB 1491205 rcpB Haemophilus ducreyi 35000HP rough colony protein B NP_873738.1 1067682 R 233412 CDS NP_873739.1 33152386 1491206 complement(1068170..1069540) 1 NC_002940.2 rough colony protein A 1069540 rcpA 1491206 rcpA Haemophilus ducreyi 35000HP rough colony protein A NP_873739.1 1068170 R 233412 CDS NP_873740.1 33152387 1491207 complement(1069540..1070376) 1 NC_002940.2 flp operon protein C 1070376 1491207 HD1308 Haemophilus ducreyi 35000HP flp operon protein C NP_873740.1 1069540 R 233412 CDS NP_873741.1 33152388 1491208 complement(1070407..1070841) 1 NC_002940.2 flp operon protein B 1070841 1491208 HD1309 Haemophilus ducreyi 35000HP flp operon protein B NP_873741.1 1070407 R 233412 CDS NP_873742.1 33152389 1491209 complement(1070912..1071181) 1 NC_002940.2 flp operon protein Flp3 1071181 flp3 1491209 flp3 Haemophilus ducreyi 35000HP flp operon protein Flp3 NP_873742.1 1070912 R 233412 CDS NP_873743.1 33152390 1491210 complement(1071199..1071444) 1 NC_002940.2 flp operon protein Flp2 1071444 flp2 1491210 flp2 Haemophilus ducreyi 35000HP flp operon protein Flp2 NP_873743.1 1071199 R 233412 CDS NP_873744.1 33152391 1491211 complement(1071473..1071730) 1 NC_002940.2 flp operon protein Flp1 1071730 flp1 1491211 flp1 Haemophilus ducreyi 35000HP flp operon protein Flp1 NP_873744.1 1071473 R 233412 CDS NP_873745.1 33152392 1491212 1071787..1071894 1 NC_002940.2 hypothetical protein 1071894 1491212 HD1313 Haemophilus ducreyi 35000HP hypothetical protein NP_873745.1 1071787 D 233412 CDS NP_873746.1 33152393 1491213 complement(1071883..1072014) 1 NC_002940.2 hypothetical protein 1072014 1491213 HD1314 Haemophilus ducreyi 35000HP hypothetical protein NP_873746.1 1071883 R 233412 CDS NP_873747.1 33152394 1491214 complement(1072230..1072373) 1 NC_002940.2 hypothetical protein 1072373 1491214 HD1315 Haemophilus ducreyi 35000HP hypothetical protein NP_873747.1 1072230 R 233412 CDS NP_873748.1 33152395 1491215 1072503..1073195 1 NC_002940.2 SanA protein 1073195 sanA 1491215 sanA Haemophilus ducreyi 35000HP SanA protein NP_873748.1 1072503 D 233412 CDS NP_873749.1 33152396 1491216 1073276..1073503 1 NC_002940.2 hypothetical protein 1073503 1491216 HD1317 Haemophilus ducreyi 35000HP hypothetical protein NP_873749.1 1073276 D 233412 CDS NP_873750.1 33152397 1491217 1073627..1075123 1 NC_002940.2 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 1075123 lysS 1491217 lysS Haemophilus ducreyi 35000HP lysyl-tRNA synthetase NP_873750.1 1073627 D 233412 CDS NP_873751.1 33152398 1491218 complement(1075189..1075854) 1 NC_002940.2 integral membrane protein 1075854 1491218 HD1319 Haemophilus ducreyi 35000HP integral membrane protein NP_873751.1 1075189 R 233412 CDS NP_873752.1 33152399 1491219 complement(1075866..1076690) 1 NC_002940.2 integral membrane protein 1076690 1491219 HD1320 Haemophilus ducreyi 35000HP integral membrane protein NP_873752.1 1075866 R 233412 CDS NP_873753.1 33152400 1491220 complement(1076683..1077294) 1 NC_002940.2 hypothetical protein 1077294 1491220 HD1321 Haemophilus ducreyi 35000HP hypothetical protein NP_873753.1 1076683 R 233412 CDS NP_873754.1 33152401 1491221 complement(1077316..1078242) 1 NC_002940.2 geranyltranstransferase; farnesyl-diphosphate synthase 1078242 ispA 1491221 ispA Haemophilus ducreyi 35000HP farnesyl-diphosphate synthase NP_873754.1 1077316 R 233412 CDS NP_873755.1 33152402 1491222 complement(1078211..1078435) 1 NC_002940.2 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1078435 xseB 1491222 xseB Haemophilus ducreyi 35000HP exodeoxyribonuclease VII small subunit NP_873755.1 1078211 R 233412 CDS NP_873756.1 33152403 1491223 1078487..1078594 1 NC_002940.2 hypothetical protein 1078594 1491223 HD1324 Haemophilus ducreyi 35000HP hypothetical protein NP_873756.1 1078487 D 233412 CDS NP_873757.1 33152404 1491224 1078607..1080568 1 NC_002940.2 hypothetical protein 1080568 1491224 HD1325 Haemophilus ducreyi 35000HP hypothetical protein NP_873757.1 1078607 D 233412 CDS NP_873758.1 33152405 1491225 1080829..1082427 1 NC_002940.2 hemolysin activation/secretion protein 1082427 hhdB 1491225 hhdB Haemophilus ducreyi 35000HP hemolysin activation/secretion protein NP_873758.1 1080829 D 233412 CDS NP_873759.1 33152406 1491226 1082511..1086038 1 NC_002940.2 hemolysin 1086038 hhdA 1491226 hhdA Haemophilus ducreyi 35000HP hemolysin NP_873759.1 1082511 D 233412 CDS NP_873760.1 33152407 1491227 complement(1086553..1087035) 1 NC_002940.2 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1087035 ispF 1491227 ispF Haemophilus ducreyi 35000HP 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase NP_873760.1 1086553 R 233412 CDS NP_873761.1 33152408 1491228 complement(1087037..1087717) 1 NC_002940.2 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1087717 ispD 1491228 ispD Haemophilus ducreyi 35000HP 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NP_873761.1 1087037 R 233412 CDS NP_873762.1 33152409 1491229 complement(1087731..1088006) 1 NC_002940.2 hypothetical protein 1088006 1491229 HD1330 Haemophilus ducreyi 35000HP hypothetical protein NP_873762.1 1087731 R 233412 CDS NP_873763.1 33152410 1491230 1088272..1089888 1 NC_002940.2 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 1089888 pckA 1491230 pckA Haemophilus ducreyi 35000HP phosphoenolpyruvate carboxykinase NP_873763.1 1088272 D 233412 CDS NP_873764.1 33152411 1491231 complement(1089949..1090806) 1 NC_002940.2 hypothetical protein 1090806 LapB 1491231 LapB Haemophilus ducreyi 35000HP hypothetical protein NP_873764.1 1089949 R 233412 CDS NP_873765.1 33152412 1491232 complement(1090888..1092099) 1 NC_002940.2 pyruvate dehydrogenase E2 component; dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex 1092099 sucB 1491232 sucB Haemophilus ducreyi 35000HP dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex NP_873765.1 1090888 R 233412 CDS NP_873766.1 33152413 1491233 complement(1092185..1095046) 1 NC_002940.2 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 1095046 sucA 1491233 sucA Haemophilus ducreyi 35000HP 2-oxoglutarate dehydrogenase E1 NP_873766.1 1092185 R 233412 CDS NP_873767.1 33152414 1491234 complement(1095241..1096035) 1 NC_002940.2 zinc ABC transporter ATP-binding protein 1096035 znuC 1491234 znuC Haemophilus ducreyi 35000HP zinc ABC transporter ATP-binding protein NP_873767.1 1095241 R 233412 CDS NP_873768.1 33152415 1491235 1096165..1097721 1 NC_002940.2 hypothetical protein 1097721 1491235 HD1339 Haemophilus ducreyi 35000HP hypothetical protein NP_873768.1 1096165 D 233412 CDS NP_873769.1 33152416 1491236 1097752..1098447 1 NC_002940.2 thiol:disulfide interchange protein 1098447 dsbC 1491236 dsbC Haemophilus ducreyi 35000HP thiol:disulfide interchange protein NP_873769.1 1097752 D 233412 CDS NP_873770.1 33152417 1491237 1098531..1100252 1 NC_002940.2 single-stranded-DNA-specific exonuclease RecJ 1100252 recJ 1491237 recJ Haemophilus ducreyi 35000HP single-stranded-DNA-specific exonuclease RecJ NP_873770.1 1098531 D 233412 CDS NP_873771.1 33152418 1491238 1100261..1100362 1 NC_002940.2 hypothetical protein 1100362 1491238 HD1343 Haemophilus ducreyi 35000HP hypothetical protein NP_873771.1 1100261 D 233412 CDS NP_873772.1 33152419 1491239 1100438..1101262 1 NC_002940.2 hypothetical protein 1101262 1491239 HD1344 Haemophilus ducreyi 35000HP hypothetical protein NP_873772.1 1100438 D 233412 CDS NP_873773.1 33152420 1491241 1103152..1103742 1 NC_002940.2 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 1103742 1491241 HD1348 Haemophilus ducreyi 35000HP deoxyribonucleotide triphosphate pyrophosphatase NP_873773.1 1103152 D 233412 CDS NP_873774.1 33152421 1491242 1103793..1104110 1 NC_002940.2 hypothetical protein 1104110 1491242 HD1349 Haemophilus ducreyi 35000HP hypothetical protein NP_873774.1 1103793 D 233412 CDS NP_873775.1 33152422 1491243 1104201..1105226 1 NC_002940.2 protease DegS 1105226 degS 1491243 degS Haemophilus ducreyi 35000HP protease DegS NP_873775.1 1104201 D 233412 CDS NP_873776.1 33152423 1491244 1105257..1105931 1 NC_002940.2 cytidylate kinase; cytidine monophosphate kinase 1105931 cmk 1491244 cmk Haemophilus ducreyi 35000HP cytidine monophosphate kinase NP_873776.1 1105257 D 233412 CDS NP_873777.1 33152424 1491245 1106027..1107694 1 NC_002940.2 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1107694 rpsA 1491245 rpsA Haemophilus ducreyi 35000HP 30S ribosomal protein S1 NP_873777.1 1106027 D 233412 CDS NP_873778.1 33152425 1491246 1107771..1108052 1 NC_002940.2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1108052 ihfB 1491246 ihfB Haemophilus ducreyi 35000HP integration host factor subunit beta NP_873778.1 1107771 D 233412 CDS NP_873779.1 33152426 1491247 1108106..1108393 1 NC_002940.2 hypothetical protein 1108393 1491247 HD1354 Haemophilus ducreyi 35000HP hypothetical protein NP_873779.1 1108106 D 233412 CDS NP_873780.1 33152427 1491248 1108393..1109583 1 NC_002940.2 tetratricopeptide repeat protein 1109583 1491248 HD1355 Haemophilus ducreyi 35000HP tetratricopeptide repeat protein NP_873780.1 1108393 D 233412 CDS NP_873781.1 33152428 1491249 1109619..1110311 1 NC_002940.2 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1110311 pyrF 1491249 pyrF Haemophilus ducreyi 35000HP orotidine 5'-phosphate decarboxylase NP_873781.1 1109619 D 233412 CDS NP_873782.1 33152429 1491250 1110383..1110694 1 NC_002940.2 involved in start site selection during the initiation of translation; translation initiation factor Sui1 1110694 1491250 HD1357 Haemophilus ducreyi 35000HP translation initiation factor Sui1 NP_873782.1 1110383 D 233412 CDS NP_873783.1 33152430 1491251 complement(1110738..1111178) 1 NC_002940.2 hypothetical protein 1111178 1491251 HD1359 Haemophilus ducreyi 35000HP hypothetical protein NP_873783.1 1110738 R 233412 CDS NP_873784.1 33152431 1491252 complement(1111191..1111754) 1 NC_002940.2 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; aromatic acid decarboxylase 1111754 ubiX 1491252 ubiX Haemophilus ducreyi 35000HP aromatic acid decarboxylase NP_873784.1 1111191 R 233412 CDS NP_873785.1 33152432 1491253 complement(1111824..1112195) 1 NC_002940.2 hypothetical protein 1112195 1491253 HD1361 Haemophilus ducreyi 35000HP hypothetical protein NP_873785.1 1111824 R 233412 CDS NP_873786.1 33152433 1491254 complement(1112231..1112761) 1 NC_002940.2 hypothetical protein 1112761 1491254 HD1362 Haemophilus ducreyi 35000HP hypothetical protein NP_873786.1 1112231 R 233412 CDS NP_873787.1 33152434 1491255 1112855..1114204 1 NC_002940.2 antibiotic maturation factor PmbA 1114204 pmbA 1491255 pmbA Haemophilus ducreyi 35000HP antibiotic maturation factor PmbA NP_873787.1 1112855 D 233412 CDS NP_873788.1 33152435 1491256 1114287..1114415 1 NC_002940.2 hypothetical protein 1114415 1491256 HD1364 Haemophilus ducreyi 35000HP hypothetical protein NP_873788.1 1114287 D 233412 CDS NP_873789.1 33152436 1491257 complement(1114404..1115087) 1 NC_002940.2 carbonic anhydrase 1115087 1491257 HD1365 Haemophilus ducreyi 35000HP carbonic anhydrase NP_873789.1 1114404 R 233412 CDS NP_873790.1 33152437 1491258 complement(1115208..1115414) 1 NC_002940.2 cold shock-like protein CspD 1115414 cspD 1491258 cspD Haemophilus ducreyi 35000HP cold shock-like protein CspD NP_873790.1 1115208 R 233412 CDS NP_873791.1 33152438 1491259 complement(1115522..1116112) 1 NC_002940.2 hypothetical protein 1116112 1491259 HD1367 Haemophilus ducreyi 35000HP hypothetical protein NP_873791.1 1115522 R 233412 CDS NP_873792.1 33152439 1491260 1116293..1117441 1 NC_002940.2 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1117441 tgt 1491260 tgt Haemophilus ducreyi 35000HP queuine tRNA-ribosyltransferase NP_873792.1 1116293 D 233412 CDS NP_873793.1 33152440 1491261 complement(1117526..1118125) 1 NC_002940.2 hypothetical protein 1118125 1491261 HD1369 Haemophilus ducreyi 35000HP hypothetical protein NP_873793.1 1117526 R 233412 CDS NP_873794.1 33152441 1491262 complement(1118195..1119457) 1 NC_002940.2 phosphate permease 1119457 1491262 HD1370 Haemophilus ducreyi 35000HP phosphate permease NP_873794.1 1118195 R 233412 CDS NP_873795.1 33152442 1491263 complement(1119467..1120147) 1 NC_002940.2 hypothetical protein 1120147 1491263 HD1371 Haemophilus ducreyi 35000HP hypothetical protein NP_873795.1 1119467 R 233412 CDS NP_873796.1 33152443 1491264 1120452..1121888 1 NC_002940.2 replicative DNA helicase 1121888 dnaB2 1491264 dnaB2 Haemophilus ducreyi 35000HP replicative DNA helicase NP_873796.1 1120452 D 233412 CDS NP_873797.1 33152444 1491265 1121866..1122165 1 NC_002940.2 hypothetical protein 1122165 1491265 HD1373 Haemophilus ducreyi 35000HP hypothetical protein NP_873797.1 1121866 D 233412 CDS NP_873798.1 33152445 1491266 1122165..1122614 1 NC_002940.2 transcriptional regulator NrdR 1122614 nrdR 1491266 nrdR Haemophilus ducreyi 35000HP transcriptional regulator NrdR NP_873798.1 1122165 D 233412 CDS NP_873799.1 33152446 1491267 complement(1122685..1124040) 1 NC_002940.2 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase 1124040 lysC 1491267 lysC Haemophilus ducreyi 35000HP aspartate kinase NP_873799.1 1122685 R 233412 CDS NP_873800.1 33152447 1491268 1124437..1124544 1 NC_002940.2 hypothetical protein 1124544 1491268 HD1376 Haemophilus ducreyi 35000HP hypothetical protein NP_873800.1 1124437 D 233412 CDS NP_873801.1 33152448 1491269 complement(1124541..1124876) 1 NC_002940.2 hypothetical protein 1124876 1491269 HD1377 Haemophilus ducreyi 35000HP hypothetical protein NP_873801.1 1124541 R 233412 CDS NP_873802.1 33152449 1491270 1125045..1126568 1 NC_002940.2 metaphosphatase; exopolyphosphatase 1126568 ppx 1491270 ppx Haemophilus ducreyi 35000HP exopolyphosphatase NP_873802.1 1125045 D 233412 CDS NP_873803.1 33152450 1491271 1126725..1127192 1 NC_002940.2 hypothetical protein 1127192 1491271 HD1379 Haemophilus ducreyi 35000HP hypothetical protein NP_873803.1 1126725 D 233412 CDS NP_873804.1 33152451 1491272 1127211..1128089 1 NC_002940.2 transcriptional regulator 1128089 1491272 HD1380 Haemophilus ducreyi 35000HP transcriptional regulator NP_873804.1 1127211 D 233412 CDS NP_873805.1 33152452 1491273 1128127..1128252 1 NC_002940.2 hypothetical protein 1128252 1491273 HD1381 Haemophilus ducreyi 35000HP hypothetical protein NP_873805.1 1128127 D 233412 CDS NP_873806.1 33152453 1491274 1128236..1129324 1 NC_002940.2 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1129324 serC 1491274 serC Haemophilus ducreyi 35000HP phosphoserine aminotransferase NP_873806.1 1128236 D 233412 CDS NP_873807.1 33152454 1491275 1129395..1130702 1 NC_002940.2 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1130702 aroA 1491275 aroA Haemophilus ducreyi 35000HP 3-phosphoshikimate 1-carboxyvinyltransferase NP_873807.1 1129395 D 233412 CDS NP_873808.1 33152455 1491276 1130797..1132110 1 NC_002940.2 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 1132110 argA 1491276 argA Haemophilus ducreyi 35000HP N-acetylglutamate synthase NP_873808.1 1130797 D 233412 CDS NP_873809.1 33152456 1491277 1132309..1134912 1 NC_002940.2 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1134912 topA 1491277 topA Haemophilus ducreyi 35000HP DNA topoisomerase I NP_873809.1 1132309 D 233412 CDS NP_873810.1 33152457 1491278 complement(1134948..1136744) 1 NC_002940.2 hypothetical protein 1136744 1491278 HD1386 Haemophilus ducreyi 35000HP hypothetical protein NP_873810.1 1134948 R 233412 CDS NP_873811.1 33152458 1491279 complement(1136755..1137231) 1 NC_002940.2 metalloprotease 1137231 1491279 HD1387 Haemophilus ducreyi 35000HP metalloprotease NP_873811.1 1136755 R 233412 CDS NP_873812.1 33152459 1491280 complement(1137315..1137770) 1 NC_002940.2 molybdopterin synthetase subunit 2; molybdopterin converting factor subunit 2 1137770 moaE 1491280 moaE Haemophilus ducreyi 35000HP molybdopterin converting factor subunit 2 NP_873812.1 1137315 R 233412 CDS NP_873813.1 33152460 1491281 complement(1137772..1138017) 1 NC_002940.2 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 1138017 moaD 1491281 moaD Haemophilus ducreyi 35000HP molybdopterin synthase small subunit NP_873813.1 1137772 R 233412 CDS NP_873814.1 33152461 1491282 complement(1138043..1138519) 1 NC_002940.2 molybdenum cofactor biosynthesis protein C 1138519 moaC 1491282 moaC Haemophilus ducreyi 35000HP molybdenum cofactor biosynthesis protein C NP_873814.1 1138043 R 233412 CDS NP_873815.1 33152462 1491283 complement(1138583..1139605) 1 NC_002940.2 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 1139605 moaA 1491283 moaA Haemophilus ducreyi 35000HP molybdenum cofactor biosynthesis protein A NP_873815.1 1138583 R 233412 CDS NP_873816.1 33152463 1491284 1140030..1141148 1 NC_002940.2 cytochrome c-type protein TorY 1141148 torY 1491284 torY Haemophilus ducreyi 35000HP cytochrome c-type protein TorY NP_873816.1 1140030 D 233412 CDS NP_873817.1 33152464 1491285 1141346..1143820 1 NC_002940.2 trimethylamine-N-oxide reductase 2; TMAO reductase 2 1143820 torZ 1491285 torZ Haemophilus ducreyi 35000HP TMAO reductase 2 NP_873817.1 1141346 D 233412 CDS NP_873818.1 33152465 1491286 1143916..1144008 1 NC_002940.2 hypothetical protein 1144008 1491286 HD1395 Haemophilus ducreyi 35000HP hypothetical protein NP_873818.1 1143916 D 233412 CDS NP_873819.2 229220789 1491287 1144053..1145039 1 NC_002940.2 RNA 2'-O-ribose methyltransferase 1145039 1491287 HD1396 Haemophilus ducreyi 35000HP RNA 2'-O-ribose methyltransferase NP_873819.2 1144053 D 233412 CDS NP_873820.1 33152467 1491288 1145196..1146005 1 NC_002940.2 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1146005 dapB 1491288 dapB Haemophilus ducreyi 35000HP dihydrodipicolinate reductase NP_873820.1 1145196 D 233412 CDS NP_873821.1 33152468 1491289 1146084..1146623 1 NC_002940.2 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 1146623 hpt 1491289 hpt Haemophilus ducreyi 35000HP hypoxanthine-guanine phosphoribosyltransferase NP_873821.1 1146084 D 233412 CDS NP_873822.1 33152469 1491290 1146724..1148856 1 NC_002940.2 soluble lytic murein transglycosylase 1148856 1491290 HD1400 Haemophilus ducreyi 35000HP soluble lytic murein transglycosylase NP_873822.1 1146724 D 233412 CDS NP_873823.1 33152470 1491292 complement(1150589..1152259) 1 NC_002940.2 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 1152259 glnS 1491292 glnS Haemophilus ducreyi 35000HP glutaminyl-tRNA synthetase NP_873823.1 1150589 R 233412 CDS NP_873824.1 33152471 1491293 complement(1152428..1152550) 1 NC_002940.2 hypothetical protein 1152550 1491293 HD1405 Haemophilus ducreyi 35000HP hypothetical protein NP_873824.1 1152428 R 233412 CDS NP_873825.1 33152472 1491294 complement(1152557..1153123) 1 NC_002940.2 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1153123 efp 1491294 efp Haemophilus ducreyi 35000HP elongation factor P NP_873825.1 1152557 R 233412 CDS NP_873826.1 33152473 1491295 1153123..1153227 1 NC_002940.2 hypothetical protein 1153227 1491295 HD1408 Haemophilus ducreyi 35000HP hypothetical protein NP_873826.1 1153123 D 233412 CDS NP_873827.1 33152474 1491296 1153275..1153847 1 NC_002940.2 hypothetical protein 1153847 1491296 HD1409 Haemophilus ducreyi 35000HP hypothetical protein NP_873827.1 1153275 D 233412 CDS NP_873828.1 33152475 1491297 1153915..1154907 1 NC_002940.2 hypothetical protein 1154907 1491297 HD1410 Haemophilus ducreyi 35000HP hypothetical protein NP_873828.1 1153915 D 233412 CDS NP_873829.1 33152476 1491298 complement(1155010..1156413) 1 NC_002940.2 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1156413 asnC 1491298 asnC Haemophilus ducreyi 35000HP asparaginyl-tRNA synthetase NP_873829.1 1155010 R 233412 CDS NP_873830.1 33152477 1491299 1156909..1158450 1 NC_002940.2 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 1158450 sbcB 1491299 sbcB Haemophilus ducreyi 35000HP exonuclease I NP_873830.1 1156909 D 233412 CDS NP_873831.1 33152478 1491300 1158472..1159071 1 NC_002940.2 hypothetical protein 1159071 1491300 HD1413 Haemophilus ducreyi 35000HP hypothetical protein NP_873831.1 1158472 D 233412 CDS NP_873832.1 33152479 1491301 1159075..1159902 1 NC_002940.2 metal-dependent phosphoesterase 1159902 trpH 1491301 trpH Haemophilus ducreyi 35000HP metal-dependent phosphoesterase NP_873832.1 1159075 D 233412 CDS NP_873833.1 33152480 1491302 1159958..1161985 1 NC_002940.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1161985 uvrB 1491302 uvrB Haemophilus ducreyi 35000HP excinuclease ABC subunit B NP_873833.1 1159958 D 233412 CDS NP_873834.1 33152481 1491303 1162098..1162340 1 NC_002940.2 hypothetical protein 1162340 1491303 HD1417 Haemophilus ducreyi 35000HP hypothetical protein NP_873834.1 1162098 D 233412 CDS NP_873835.1 33152482 1491304 1162475..1163761 1 NC_002940.2 aminopeptidase P II; Xaa-Pro aminopeptidase 1163761 pepP 1491304 pepP Haemophilus ducreyi 35000HP Xaa-Pro aminopeptidase NP_873835.1 1162475 D 233412 CDS NP_873836.1 33152483 1491305 complement(1163837..1165027) 1 NC_002940.2 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1165027 aspC 1491305 aspC Haemophilus ducreyi 35000HP aromatic amino acid aminotransferase NP_873836.1 1163837 R 233412 CDS NP_873837.1 33152484 1491306 1165105..1165206 1 NC_002940.2 hypothetical protein 1165206 1491306 HD1420 Haemophilus ducreyi 35000HP hypothetical protein NP_873837.1 1165105 D 233412 CDS NP_873838.1 33152485 1491307 complement(1165289..1165609) 1 NC_002940.2 phosphoribosylaminoimidazole carboxylase ATPase subunit (C terminal) 1165609 1491307 HD1421 Haemophilus ducreyi 35000HP phosphoribosylaminoimidazole carboxylase ATPase subunit (C terminal) NP_873838.1 1165289 R 233412 CDS NP_873839.1 33152486 1491308 complement(1165789..1165941) 1 NC_002940.2 hypothetical protein 1165941 1491308 HD1422 Haemophilus ducreyi 35000HP hypothetical protein NP_873839.1 1165789 R 233412 CDS NP_873840.1 33152487 1491309 complement(1165928..1166254) 1 NC_002940.2 phosphoribosylaminoimidazole carboxylase ATPase subunit 1166254 1491309 HD1423 Haemophilus ducreyi 35000HP phosphoribosylaminoimidazole carboxylase ATPase subunit NP_873840.1 1165928 R 233412 CDS NP_873841.1 33152488 1491310 complement(1166285..1166773) 1 NC_002940.2 Catalyzes a step in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase catalytic subunit 1166773 purE 1491310 purE Haemophilus ducreyi 35000HP phosphoribosylaminoimidazole carboxylase catalytic subunit NP_873841.1 1166285 R 233412 CDS NP_873842.1 33152489 1491311 1166987..1167631 1 NC_002940.2 stringent starvation protein A 1167631 sspA 1491311 sspA Haemophilus ducreyi 35000HP stringent starvation protein A NP_873842.1 1166987 D 233412 CDS NP_873843.1 33152490 1491312 1167631..1168032 1 NC_002940.2 ClpXP protease specificity-enhancing factor 1168032 sspB 1491312 sspB Haemophilus ducreyi 35000HP ClpXP protease specificity-enhancing factor NP_873843.1 1167631 D 233412 CDS NP_873844.1 33152491 1491313 complement(1168112..1168879) 1 NC_002940.2 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1168879 hlyX 1491313 hlyX Haemophilus ducreyi 35000HP fumarate/nitrate reduction transcriptional regulator NP_873844.1 1168112 R 233412 CDS NP_873845.1 33152492 1491314 1169132..1169557 1 NC_002940.2 universal stress protein A 1169557 uspA 1491314 uspA Haemophilus ducreyi 35000HP universal stress protein A NP_873845.1 1169132 D 233412 CDS NP_873846.1 33152493 1491315 1169725..1172349 1 NC_002940.2 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1172349 alaS 1491315 alaS Haemophilus ducreyi 35000HP alanyl-tRNA synthetase NP_873846.1 1169725 D 233412 CDS NP_873847.1 33152494 1491316 1172406..1172594 1 NC_002940.2 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 1172594 csrA 1491316 csrA Haemophilus ducreyi 35000HP carbon storage regulator NP_873847.1 1172406 D 233412 CDS NP_873848.1 33152495 1491317 1172605..1173492 1 NC_002940.2 UTP-glucose-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase 1173492 galU 1491317 galU Haemophilus ducreyi 35000HP UDP-glucose pyrophosphorylase NP_873848.1 1172605 D 233412 CDS NP_873849.1 33152496 1491318 complement(1173520..1174047) 1 NC_002940.2 hypothetical protein 1174047 1491318 HD1432 Haemophilus ducreyi 35000HP hypothetical protein NP_873849.1 1173520 R 233412 CDS NP_873850.1 33152497 1491319 1174546..1175820 1 NC_002940.2 outer membrane protein P2-like protein 1175820 ompP2A 1491319 ompP2A Haemophilus ducreyi 35000HP outer membrane protein P2-like protein NP_873850.1 1174546 D 233412 CDS NP_873851.1 33152498 1491320 1176086..1176184 1 NC_002940.2 hypothetical protein 1176184 1491320 HD1434 Haemophilus ducreyi 35000HP hypothetical protein NP_873851.1 1176086 D 233412 CDS NP_873852.1 33152499 1491321 1176194..1177387 1 NC_002940.2 outer membrane protein P2-like protein 1177387 ompP2B 1491321 ompP2B Haemophilus ducreyi 35000HP outer membrane protein P2-like protein NP_873852.1 1176194 D 233412 CDS NP_873853.1 33152500 1491322 complement(1177679..1178803) 1 NC_002940.2 phage-related secreted protein 1178803 1491322 HD1436 Haemophilus ducreyi 35000HP phage-related secreted protein NP_873853.1 1177679 R 233412 CDS NP_873854.1 33152501 1491323 complement(1178815..1179117) 1 NC_002940.2 phage-related membrane protein 1179117 1491323 HD1437 Haemophilus ducreyi 35000HP phage-related membrane protein NP_873854.1 1178815 R 233412 CDS NP_873855.1 33152502 1491324 complement(1179126..1180271) 1 NC_002940.2 hypothetical protein 1180271 1491324 HD1439 Haemophilus ducreyi 35000HP hypothetical protein NP_873855.1 1179126 R 233412 CDS NP_873856.1 33152503 1491325 complement(1180396..1180617) 1 NC_002940.2 hypothetical protein 1180617 1491325 HD1441 Haemophilus ducreyi 35000HP hypothetical protein NP_873856.1 1180396 R 233412 CDS NP_873857.1 33152504 1491326 complement(1180635..1180877) 1 NC_002940.2 hypothetical protein 1180877 1491326 HD1442 Haemophilus ducreyi 35000HP hypothetical protein NP_873857.1 1180635 R 233412 CDS NP_873858.1 33152505 1491327 complement(1180874..1181200) 1 NC_002940.2 single stranded DNA-binding protien 1181200 1491327 HD1443 Haemophilus ducreyi 35000HP single stranded DNA-binding protien NP_873858.1 1180874 R 233412 CDS NP_873859.1 33152506 1491328 complement(1181231..1182385) 1 NC_002940.2 hypothetical protein 1182385 1491328 HD1444 Haemophilus ducreyi 35000HP hypothetical protein NP_873859.1 1181231 R 233412 CDS NP_873860.1 33152507 1491329 1182543..1182734 1 NC_002940.2 RstR-like phage repressor protein 1182734 plpR1 1491329 plpR1 Haemophilus ducreyi 35000HP RstR-like phage repressor protein NP_873860.1 1182543 D 233412 CDS NP_873861.1 33152508 1491330 1182724..1183227 1 NC_002940.2 hypothetical protein 1183227 1491330 HD1445 Haemophilus ducreyi 35000HP hypothetical protein NP_873861.1 1182724 D 233412 CDS NP_873862.1 33152509 1491331 complement(1183331..1183618) 1 NC_002940.2 hypothetical protein 1183618 1491331 HD1446 Haemophilus ducreyi 35000HP hypothetical protein NP_873862.1 1183331 R 233412 CDS NP_873863.1 33152510 1491332 1183859..1185346 1 NC_002940.2 nicotinate phosphoribosyltransferase 1185346 nadV1 1491332 nadV1 Haemophilus ducreyi 35000HP nicotinate phosphoribosyltransferase NP_873863.1 1183859 D 233412 CDS NP_873864.1 33152511 1491333 complement(1185963..1186184) 1 NC_002940.2 hypothetical protein 1186184 1491333 HD1449 Haemophilus ducreyi 35000HP hypothetical protein NP_873864.1 1185963 R 233412 CDS NP_873865.1 33152512 1491334 complement(1186202..1186444) 1 NC_002940.2 hypothetical protein 1186444 1491334 HD1450 Haemophilus ducreyi 35000HP hypothetical protein NP_873865.1 1186202 R 233412 CDS NP_873866.1 33152513 1491335 complement(1186441..1186767) 1 NC_002940.2 hypothetical protein 1186767 1491335 HD1451 Haemophilus ducreyi 35000HP hypothetical protein NP_873866.1 1186441 R 233412 CDS NP_873867.1 33152514 1491336 complement(1186798..1187964) 1 NC_002940.2 hypothetical protein 1187964 1491336 HD1452 Haemophilus ducreyi 35000HP hypothetical protein NP_873867.1 1186798 R 233412 CDS NP_873868.1 33152515 1491337 1188110..1188301 1 NC_002940.2 RstR-like phage repressor protein 1188301 plpR2 1491337 plpR2 Haemophilus ducreyi 35000HP RstR-like phage repressor protein NP_873868.1 1188110 D 233412 CDS NP_873869.1 33152516 1491338 1188291..1188794 1 NC_002940.2 hypothetical protein 1188794 1491338 HD1453 Haemophilus ducreyi 35000HP hypothetical protein NP_873869.1 1188291 D 233412 CDS NP_873870.1 33152517 1491339 complement(1188898..1189185) 1 NC_002940.2 hypothetical protein 1189185 1491339 HD1454 Haemophilus ducreyi 35000HP hypothetical protein NP_873870.1 1188898 R 233412 CDS NP_873871.1 33152518 1491340 1189426..1190913 1 NC_002940.2 nicotinate phosphoribosyltransferase 1190913 nadV2 1491340 nadV2 Haemophilus ducreyi 35000HP nicotinate phosphoribosyltransferase NP_873871.1 1189426 D 233412 CDS NP_873872.1 33152519 1491341 1191116..1192318 1 NC_002940.2 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1192318 ackA 1491341 ackA Haemophilus ducreyi 35000HP acetate kinase NP_873872.1 1191116 D 233412 CDS NP_873873.1 33152520 1491342 1192390..1194528 1 NC_002940.2 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 1194528 pta 1491342 pta Haemophilus ducreyi 35000HP phosphate acetyltransferase NP_873873.1 1192390 D 233412 CDS NP_873874.1 33152521 1491343 complement(1194634..1195551) 1 NC_002940.2 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1195551 truB 1491343 truB Haemophilus ducreyi 35000HP tRNA pseudouridine synthase B NP_873874.1 1194634 R 233412 CDS NP_873875.1 33152522 1491344 complement(1195555..1195935) 1 NC_002940.2 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1195935 rbfA 1491344 rbfA Haemophilus ducreyi 35000HP ribosome-binding factor A NP_873875.1 1195555 R 233412 CDS NP_873876.1 33152523 1491345 complement(1195996..1198515) 1 NC_002940.2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1198515 infB 1491345 infB Haemophilus ducreyi 35000HP translation initiation factor IF-2 NP_873876.1 1195996 R 233412 CDS NP_873877.1 33152524 1491346 complement(1198537..1200018) 1 NC_002940.2 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1200018 nusA 1491346 nusA Haemophilus ducreyi 35000HP transcription elongation factor NusA NP_873877.1 1198537 R 233412 CDS NP_873878.1 33152525 1491347 complement(1200035..1200499) 1 NC_002940.2 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1200499 1491347 HD1463 Haemophilus ducreyi 35000HP hypothetical protein NP_873878.1 1200035 R 233412 CDS NP_873879.1 33152526 1491349 complement(1200963..1202264) 1 NC_002940.2 bifunctional folylpolyglutamate synthase/dihydrofolate synthase 1202264 folC 1491349 folC Haemophilus ducreyi 35000HP bifunctional folylpolyglutamate synthase/dihydrofolate synthase NP_873879.1 1200963 R 233412 CDS NP_873880.1 33152527 1491350 complement(1202264..1203154) 1 NC_002940.2 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 1203154 accD 1491350 accD Haemophilus ducreyi 35000HP acetyl-CoA carboxylase subunit beta NP_873880.1 1202264 R 233412 CDS NP_873881.1 33152528 1491351 1203517..1204314 1 NC_002940.2 MazG protein 1204314 mazG 1491351 mazG Haemophilus ducreyi 35000HP MazG protein NP_873881.1 1203517 D 233412 CDS NP_873882.1 33152529 1491352 1204379..1205101 1 NC_002940.2 transcriptional regulatory protein CpxR 1205101 cpxR 1491352 cpxR Haemophilus ducreyi 35000HP transcriptional regulatory protein CpxR NP_873882.1 1204379 D 233412 CDS NP_873883.1 33152530 1491353 1205164..1206558 1 NC_002940.2 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 1206558 cpxA 1491353 cpxA Haemophilus ducreyi 35000HP two-component sensor protein NP_873883.1 1205164 D 233412 CDS NP_873884.1 33152531 1491354 1206644..1207417 1 NC_002940.2 hypothetical protein 1207417 1491354 HD1471 Haemophilus ducreyi 35000HP hypothetical protein NP_873884.1 1206644 D 233412 CDS NP_873885.1 33152532 1491355 1207580..1207798 1 NC_002940.2 hypothetical protein 1207798 1491355 HD1472 Haemophilus ducreyi 35000HP hypothetical protein NP_873885.1 1207580 D 233412 CDS NP_873886.1 33152533 1491356 1207853..1208449 1 NC_002940.2 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1208449 tdk 1491356 tdk Haemophilus ducreyi 35000HP thymidine kinase NP_873886.1 1207853 D 233412 CDS NP_873887.1 33152534 1491357 complement(1208489..1209181) 1 NC_002940.2 hypothetical protein 1209181 1491357 HD1474 Haemophilus ducreyi 35000HP hypothetical protein NP_873887.1 1208489 R 233412 CDS NP_873888.1 33152535 1491358 complement(1209216..1210328) 1 NC_002940.2 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1210328 aroG 1491358 aroG Haemophilus ducreyi 35000HP phospho-2-dehydro-3-deoxyheptonate aldolase NP_873888.1 1209216 R 233412 CDS NP_873889.1 33152536 1491359 complement(1210578..1213451) 1 NC_002940.2 cell division protein FtsK 1213451 ftsK 1491359 ftsK Haemophilus ducreyi 35000HP cell division protein FtsK NP_873889.1 1210578 R 233412 CDS NP_873890.1 33152537 1491360 complement(1213455..1213937) 1 NC_002940.2 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 1213937 lrp 1491360 lrp Haemophilus ducreyi 35000HP leucine-responsive transcriptional regulator NP_873890.1 1213455 R 233412 CDS NP_873891.1 33152538 1491361 complement(1214014..1215135) 1 NC_002940.2 ribonuclease D 1215135 rnd 1491361 rnd Haemophilus ducreyi 35000HP ribonuclease D NP_873891.1 1214014 R 233412 CDS NP_873892.1 33152539 1491362 1215283..1216515 1 NC_002940.2 transcriptional repressor of carbohydrate metabolism; PTS operon 1216515 mlc 1491362 mlc Haemophilus ducreyi 35000HP transcriptional repressor of carbohydrate metabolism; PTS operon NP_873892.1 1215283 D 233412 CDS NP_873893.1 33152540 1491363 1216452..1217288 1 NC_002940.2 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1217288 bioD 1491363 bioD Haemophilus ducreyi 35000HP dithiobiotin synthetase NP_873893.1 1216452 D 233412 CDS NP_873894.1 33152541 1491364 complement(1217485..1218000) 1 NC_002940.2 lipoprotein 1218000 1491364 HD1481 Haemophilus ducreyi 35000HP lipoprotein NP_873894.1 1217485 R 233412 CDS NP_873895.1 33152542 1491365 complement(1218059..1218355) 1 NC_002940.2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1218355 ihfA 1491365 ihfA Haemophilus ducreyi 35000HP integration host factor subunit alpha NP_873895.1 1218059 R 233412 CDS NP_873896.1 33152543 1491366 complement(1218371..1220758) 1 NC_002940.2 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1220758 pheT 1491366 pheT Haemophilus ducreyi 35000HP phenylalanyl-tRNA synthetase subunit beta NP_873896.1 1218371 R 233412 CDS NP_873897.1 33152544 1491367 complement(1220830..1221813) 1 NC_002940.2 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1221813 pheS 1491367 pheS Haemophilus ducreyi 35000HP phenylalanyl-tRNA synthetase subunit alpha NP_873897.1 1220830 R 233412 CDS NP_873898.1 33152545 1491368 1222071..1222733 1 NC_002940.2 NAD(P)H nitroreductase 1222733 frxA 1491368 frxA Haemophilus ducreyi 35000HP NAD(P)H nitroreductase NP_873898.1 1222071 D 233412 CDS NP_873899.1 33152546 1491369 complement(1222797..1223570) 1 NC_002940.2 hypothetical protein 1223570 1491369 HD1486 Haemophilus ducreyi 35000HP hypothetical protein NP_873899.1 1222797 R 233412 CDS NP_873900.1 33152547 1491370 complement(1223551..1224474) 1 NC_002940.2 transmembrane efflux protein 1224474 1491370 HD1487 Haemophilus ducreyi 35000HP transmembrane efflux protein NP_873900.1 1223551 R 233412 CDS NP_873901.1 33152548 1491371 complement(1224502..1225041) 1 NC_002940.2 hypothetical protein 1225041 1491371 HD1489 Haemophilus ducreyi 35000HP hypothetical protein NP_873901.1 1224502 R 233412 CDS NP_873902.1 33152549 1491373 complement(1225929..1226324) 1 NC_002940.2 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1226324 rpsI 1491373 rpsI Haemophilus ducreyi 35000HP 30S ribosomal protein S9 NP_873902.1 1225929 R 233412 CDS NP_873903.1 33152550 1491374 complement(1226341..1226763) 1 NC_002940.2 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1226763 rplM 1491374 rplM Haemophilus ducreyi 35000HP 50S ribosomal protein L13 NP_873903.1 1226341 R 233412 CDS NP_873904.1 33152551 1491375 1227071..1227457 1 NC_002940.2 hypothetical protein 1227457 1491375 HD1495 Haemophilus ducreyi 35000HP hypothetical protein NP_873904.1 1227071 D 233412 CDS NP_873905.1 33152552 1491377 complement(1230139..1231356) 1 NC_002940.2 tyrosine-specific transport protein 1231356 tyrP 1491377 tyrP Haemophilus ducreyi 35000HP tyrosine-specific transport protein NP_873905.1 1230139 R 233412 CDS NP_873906.1 33152553 1491378 complement(1231553..1233472) 1 NC_002940.2 cell division protein, FtsH 1233472 ftsH 1491378 ftsH Haemophilus ducreyi 35000HP cell division protein, FtsH NP_873906.1 1231553 R 233412 CDS NP_873907.1 33152554 1491379 complement(1233514..1234140) 1 NC_002940.2 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase 1234140 rrmJ 1491379 rrmJ Haemophilus ducreyi 35000HP 23S rRNA methyltransferase NP_873907.1 1233514 R 233412 CDS NP_873908.1 33152555 1491380 complement(1234292..1234387) 1 NC_002940.2 hypothetical protein 1234387 1491380 HD1502 Haemophilus ducreyi 35000HP hypothetical protein NP_873908.1 1234292 R 233412 CDS NP_873909.1 33152556 1491381 1234410..1235873 1 NC_002940.2 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 1235873 guaB 1491381 guaB Haemophilus ducreyi 35000HP inosine 5'-monophosphate dehydrogenase NP_873909.1 1234410 D 233412 CDS NP_873910.1 33152557 1491382 1236023..1237594 1 NC_002940.2 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1237594 guaA 1491382 guaA Haemophilus ducreyi 35000HP GMP synthase NP_873910.1 1236023 D 233412 CDS NP_873911.1 33152558 1491383 complement(1237841..1250299) 1 NC_002940.2 large supernatant protein 1 1250299 lspA1 1491383 lspA1 Haemophilus ducreyi 35000HP large supernatant protein 1 NP_873911.1 1237841 R 233412 CDS NP_873912.1 33152559 1491384 complement(1250848..1252509) 1 NC_002940.2 phosphomannomutase 1252509 manB 1491384 manB Haemophilus ducreyi 35000HP phosphomannomutase NP_873912.1 1250848 R 233412 CDS NP_873913.1 33152560 1491386 complement(1253431..1254801) 1 NC_002940.2 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 1254801 glmU 1491386 glmU Haemophilus ducreyi 35000HP bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase NP_873913.1 1253431 R 233412 CDS NP_873914.1 33152561 1491387 complement(1254919..1258029) 1 NC_002940.2 acriflavine resistance protein 1258029 1491387 HD1512 Haemophilus ducreyi 35000HP acriflavine resistance protein NP_873914.1 1254919 R 233412 CDS NP_873915.1 33152562 1491388 complement(1258043..1259359) 1 NC_002940.2 RND efflux membrane fusion protein 1259359 1491388 HD1513 Haemophilus ducreyi 35000HP RND efflux membrane fusion protein NP_873915.1 1258043 R 233412 CDS NP_873916.1 33152563 1491389 1259924..1260145 1 NC_002940.2 hypothetical protein 1260145 1491389 HD1515 Haemophilus ducreyi 35000HP hypothetical protein NP_873916.1 1259924 D 233412 CDS NP_873917.1 33152564 1491390 1260148..1261878 1 NC_002940.2 sulfatase 1261878 1491390 HD1516 Haemophilus ducreyi 35000HP sulfatase NP_873917.1 1260148 D 233412 CDS NP_873918.1 33152565 1491391 complement(1262080..1262430) 1 NC_002940.2 hypothetical protein 1262430 1491391 HD1517 Haemophilus ducreyi 35000HP hypothetical protein NP_873918.1 1262080 R 233412 CDS NP_873919.1 33152566 1491392 complement(1262548..1262949) 1 NC_002940.2 hypothetical protein 1262949 1491392 HD1518 Haemophilus ducreyi 35000HP hypothetical protein NP_873919.1 1262548 R 233412 CDS NP_873920.1 33152567 1491393 complement(1262939..1263313) 1 NC_002940.2 hypothetical protein 1263313 1491393 HD1519 Haemophilus ducreyi 35000HP hypothetical protein NP_873920.1 1262939 R 233412 CDS NP_873921.1 33152568 1491394 complement(1263295..1263771) 1 NC_002940.2 hypothetical protein 1263771 1491394 HD1520 Haemophilus ducreyi 35000HP hypothetical protein NP_873921.1 1263295 R 233412 CDS NP_873922.1 33152569 1491395 complement(1263755..1263874) 1 NC_002940.2 hypothetical protein 1263874 1491395 HD1522 Haemophilus ducreyi 35000HP hypothetical protein NP_873922.1 1263755 R 233412 CDS NP_873923.1 33152570 1491396 complement(1263817..1263978) 1 NC_002940.2 hypothetical protein 1263978 1491396 HD1523 Haemophilus ducreyi 35000HP hypothetical protein NP_873923.1 1263817 R 233412 CDS NP_873924.1 33152571 1491397 complement(1263975..1264187) 1 NC_002940.2 hypothetical protein 1264187 1491397 HD1524 Haemophilus ducreyi 35000HP hypothetical protein NP_873924.1 1263975 R 233412 CDS NP_873925.1 33152572 1491398 complement(1264184..1264708) 1 NC_002940.2 mu-phage host-nuclease inhibitor protein 1264708 gam 1491398 gam Haemophilus ducreyi 35000HP mu-phage host-nuclease inhibitor protein NP_873925.1 1264184 R 233412 CDS NP_873926.1 33152573 1491399 complement(1264683..1264913) 1 NC_002940.2 hypothetical protein 1264913 1491399 HD1526 Haemophilus ducreyi 35000HP hypothetical protein NP_873926.1 1264683 R 233412 CDS NP_873927.1 33152574 1491400 complement(1264906..1266111) 1 NC_002940.2 Eha protein 1266111 1491400 HD1528 Haemophilus ducreyi 35000HP Eha protein NP_873927.1 1264906 R 233412 CDS NP_873928.1 33152575 1491401 complement(1266101..1267366) 1 NC_002940.2 hypothetical protein 1267366 1491401 HD1529 Haemophilus ducreyi 35000HP hypothetical protein NP_873928.1 1266101 R 233412 CDS NP_873929.1 33152576 1491402 complement(1267353..1267931) 1 NC_002940.2 hypothetical protein 1267931 1491402 HD1530 Haemophilus ducreyi 35000HP hypothetical protein NP_873929.1 1267353 R 233412 CDS NP_873930.1 33152577 1491403 complement(1267912..1268874) 1 NC_002940.2 hypothetical protein 1268874 1491403 HD1532 Haemophilus ducreyi 35000HP hypothetical protein NP_873930.1 1267912 R 233412 CDS NP_873931.1 33152578 1491404 complement(1268904..1269206) 1 NC_002940.2 hypothetical protein 1269206 1491404 HD1533 Haemophilus ducreyi 35000HP hypothetical protein NP_873931.1 1268904 R 233412 CDS NP_873932.1 33152579 1491405 complement(1269208..1269330) 1 NC_002940.2 hypothetical protein 1269330 1491405 HD1534 Haemophilus ducreyi 35000HP hypothetical protein NP_873932.1 1269208 R 233412 CDS NP_873933.1 33152580 1491406 1269386..1269691 1 NC_002940.2 hypothetical protein 1269691 1491406 HD1535 Haemophilus ducreyi 35000HP hypothetical protein NP_873933.1 1269386 D 233412 CDS NP_873934.1 33152581 1491407 complement(1269748..1269849) 1 NC_002940.2 hypothetical protein 1269849 1491407 HD1537 Haemophilus ducreyi 35000HP hypothetical protein NP_873934.1 1269748 R 233412 CDS NP_873935.1 33152582 1491408 complement(1269856..1270050) 1 NC_002940.2 hypothetical protein 1270050 1491408 HD1538 Haemophilus ducreyi 35000HP hypothetical protein NP_873935.1 1269856 R 233412 CDS NP_873936.1 33152583 1491409 complement(1270078..1270170) 1 NC_002940.2 hypothetical protein 1270170 1491409 HD1539 Haemophilus ducreyi 35000HP hypothetical protein NP_873936.1 1270078 R 233412 CDS NP_873937.1 33152584 1491410 1270186..1270656 1 NC_002940.2 hypothetical protein 1270656 1491410 HD1540 Haemophilus ducreyi 35000HP hypothetical protein NP_873937.1 1270186 D 233412 CDS NP_873938.1 33152585 1491411 1270657..1271076 1 NC_002940.2 hypothetical protein 1271076 1491411 HD1541 Haemophilus ducreyi 35000HP hypothetical protein NP_873938.1 1270657 D 233412 CDS NP_873939.1 33152586 1491412 1271098..1271616 1 NC_002940.2 hypothetical protein 1271616 1491412 HD1542 Haemophilus ducreyi 35000HP hypothetical protein NP_873939.1 1271098 D 233412 CDS NP_873940.1 33152587 1491413 1271652..1272455 1 NC_002940.2 hypothetical protein 1272455 1491413 HD1543 Haemophilus ducreyi 35000HP hypothetical protein NP_873940.1 1271652 D 233412 CDS NP_873941.1 33152588 1491414 1272449..1272697 1 NC_002940.2 hypothetical protein 1272697 1491414 HD1545 Haemophilus ducreyi 35000HP hypothetical protein NP_873941.1 1272449 D 233412 CDS NP_873942.1 33152589 1491415 1272694..1273149 1 NC_002940.2 hypothetical protein 1273149 1491415 HD1546 Haemophilus ducreyi 35000HP hypothetical protein NP_873942.1 1272694 D 233412 CDS NP_873943.1 33152590 1491416 complement(1273271..1273603) 1 NC_002940.2 hypothetical protein 1273603 1491416 HD1547 Haemophilus ducreyi 35000HP hypothetical protein NP_873943.1 1273271 R 233412 CDS NP_873944.1 33152591 1491417 1273742..1274116 1 NC_002940.2 hypothetical protein 1274116 1491417 HD1548 Haemophilus ducreyi 35000HP hypothetical protein NP_873944.1 1273742 D 233412 CDS NP_873945.1 33152592 1491418 1274119..1274727 1 NC_002940.2 hypothetical protein 1274727 1491418 HD1549 Haemophilus ducreyi 35000HP hypothetical protein NP_873945.1 1274119 D 233412 CDS NP_873946.1 33152593 1491419 1274712..1275152 1 NC_002940.2 hypothetical protein 1275152 1491419 HD1550 Haemophilus ducreyi 35000HP hypothetical protein NP_873946.1 1274712 D 233412 CDS NP_873947.1 33152594 1491420 1275255..1275605 1 NC_002940.2 hypothetical protein 1275605 1491420 HD1552 Haemophilus ducreyi 35000HP hypothetical protein NP_873947.1 1275255 D 233412 CDS NP_873948.1 33152595 1491421 1275607..1275912 1 NC_002940.2 hypothetical protein 1275912 1491421 HD1553 Haemophilus ducreyi 35000HP hypothetical protein NP_873948.1 1275607 D 233412 CDS NP_873949.1 33152596 1491422 1275922..1276461 1 NC_002940.2 bacteriophage Mu GP27-like protein 1276461 1491422 HD1554 Haemophilus ducreyi 35000HP bacteriophage Mu GP27-like protein NP_873949.1 1275922 D 233412 CDS NP_873950.1 33152597 1491423 1276461..1278080 1 NC_002940.2 bacteriophage Mu GP28-like protein 1278080 1491423 HD1555 Haemophilus ducreyi 35000HP bacteriophage Mu GP28-like protein NP_873950.1 1276461 D 233412 CDS NP_873951.1 33152598 1491424 1278083..1279594 1 NC_002940.2 hypothetical protein 1279594 1491424 HD1556 Haemophilus ducreyi 35000HP hypothetical protein NP_873951.1 1278083 D 233412 CDS NP_873952.1 33152599 1491425 1279587..1280837 1 NC_002940.2 bacteriophage Mu GP30-like protein 1280837 1491425 HD1557 Haemophilus ducreyi 35000HP bacteriophage Mu GP30-like protein NP_873952.1 1279587 D 233412 CDS NP_873953.1 33152600 1491426 1280944..1281435 1 NC_002940.2 bacteriophage Mu G-like protein 1281435 1491426 HD1558 Haemophilus ducreyi 35000HP bacteriophage Mu G-like protein NP_873953.1 1280944 D 233412 CDS NP_873954.1 33152601 1491427 1281658..1282674 1 NC_002940.2 hypothetical protein 1282674 1491427 HD1559 Haemophilus ducreyi 35000HP hypothetical protein NP_873954.1 1281658 D 233412 CDS NP_873955.1 33152602 1491428 1282671..1283039 1 NC_002940.2 hypothetical protein 1283039 1491428 HD1560 Haemophilus ducreyi 35000HP hypothetical protein NP_873955.1 1282671 D 233412 CDS NP_873956.1 33152603 1491429 1283090..1284016 1 NC_002940.2 hypothetical protein 1284016 1491429 HD1561 Haemophilus ducreyi 35000HP hypothetical protein NP_873956.1 1283090 D 233412 CDS NP_873957.1 33152604 1491430 1284025..1284534 1 NC_002940.2 hypothetical protein 1284534 1491430 HD1562 Haemophilus ducreyi 35000HP hypothetical protein NP_873957.1 1284025 D 233412 CDS NP_873958.1 33152605 1491431 1284587..1284979 1 NC_002940.2 hypothetical protein 1284979 1491431 HD1563 Haemophilus ducreyi 35000HP hypothetical protein NP_873958.1 1284587 D 233412 CDS NP_873959.1 33152606 1491432 1284976..1285233 1 NC_002940.2 hypothetical protein 1285233 1491432 HD1564 Haemophilus ducreyi 35000HP hypothetical protein NP_873959.1 1284976 D 233412 CDS NP_873960.1 33152607 1491433 1285233..1285976 1 NC_002940.2 hypothetical protein 1285976 1491433 HD1565 Haemophilus ducreyi 35000HP hypothetical protein NP_873960.1 1285233 D 233412 CDS NP_873961.1 33152608 1491434 1286034..1286453 1 NC_002940.2 hypothetical protein 1286453 1491434 HD1567 Haemophilus ducreyi 35000HP hypothetical protein NP_873961.1 1286034 D 233412 CDS NP_873962.1 33152609 1491435 complement(1286630..1286884) 1 NC_002940.2 hypothetical protein 1286884 1491435 HD1568 Haemophilus ducreyi 35000HP hypothetical protein NP_873962.1 1286630 R 233412 CDS NP_873963.1 33152610 1491436 1286899..1290258 1 NC_002940.2 tail length tape measure protein 1290258 1491436 HD1569 Haemophilus ducreyi 35000HP tail length tape measure protein NP_873963.1 1286899 D 233412 CDS NP_873964.1 33152611 1491437 1290258..1291256 1 NC_002940.2 hypothetical protein 1291256 1491437 HD1571 Haemophilus ducreyi 35000HP hypothetical protein NP_873964.1 1290258 D 233412 CDS NP_873965.1 33152612 1491438 1291259..1292158 1 NC_002940.2 hypothetical protein 1292158 1491438 HD1572 Haemophilus ducreyi 35000HP hypothetical protein NP_873965.1 1291259 D 233412 CDS NP_873966.1 33152613 1491439 1292224..1292913 1 NC_002940.2 hypothetical protein 1292913 1491439 HD1573 Haemophilus ducreyi 35000HP hypothetical protein NP_873966.1 1292224 D 233412 CDS NP_873967.1 33152614 1491440 1292919..1293905 1 NC_002940.2 hypothetical protein 1293905 1491440 HD1574 Haemophilus ducreyi 35000HP hypothetical protein NP_873967.1 1292919 D 233412 CDS NP_873968.1 33152615 1491441 1293950..1294474 1 NC_002940.2 hypothetical protein 1294474 1491441 HD1575 Haemophilus ducreyi 35000HP hypothetical protein NP_873968.1 1293950 D 233412 CDS NP_873969.1 33152616 1491442 1294594..1294758 1 NC_002940.2 hypothetical protein 1294758 1491442 HD1576 Haemophilus ducreyi 35000HP hypothetical protein NP_873969.1 1294594 D 233412 CDS NP_873970.1 33152617 1491443 1294771..1295022 1 NC_002940.2 hypothetical protein 1295022 1491443 HD1577 Haemophilus ducreyi 35000HP hypothetical protein NP_873970.1 1294771 D 233412 CDS NP_873971.1 33152618 1491444 1295040..1295243 1 NC_002940.2 hypothetical protein 1295243 1491444 HD1578 Haemophilus ducreyi 35000HP hypothetical protein NP_873971.1 1295040 D 233412 CDS NP_873972.1 33152619 1491445 1295243..1298032 1 NC_002940.2 hypothetical protein 1298032 1491445 HD1580 Haemophilus ducreyi 35000HP hypothetical protein NP_873972.1 1295243 D 233412 CDS NP_873973.1 33152620 1491446 1298136..1299062 1 NC_002940.2 hypothetical protein 1299062 1491446 HD1581 Haemophilus ducreyi 35000HP hypothetical protein NP_873973.1 1298136 D 233412 CDS NP_873974.1 33152621 1491447 complement(1299264..1303775) 1 NC_002940.2 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1303775 mukB 1491447 mukB Haemophilus ducreyi 35000HP cell division protein MukB NP_873974.1 1299264 R 233412 CDS NP_873975.1 33152622 1491448 complement(1303775..1304491) 1 NC_002940.2 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1304491 mukE 1491448 mukE Haemophilus ducreyi 35000HP condesin subunit E NP_873975.1 1303775 R 233412 CDS NP_873976.1 33152623 1491449 complement(1304504..1305835) 1 NC_002940.2 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1305835 mukF 1491449 mukF Haemophilus ducreyi 35000HP condesin subunit F NP_873976.1 1304504 R 233412 CDS NP_873977.1 33152624 1491450 complement(1305851..1305952) 1 NC_002940.2 hypothetical protein 1305952 1491450 HD1586 Haemophilus ducreyi 35000HP hypothetical protein NP_873977.1 1305851 R 233412 CDS NP_873978.1 33152625 1491451 complement(1305968..1308214) 1 NC_002940.2 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1308214 parC 1491451 parC Haemophilus ducreyi 35000HP DNA topoisomerase IV subunit A NP_873978.1 1305968 R 233412 CDS NP_873979.1 33152626 1491452 1308506..1310644 1 NC_002940.2 polynucleotide phosphorylase 1310644 pnp 1491452 pnp Haemophilus ducreyi 35000HP polynucleotide phosphorylase NP_873979.1 1308506 D 233412 CDS NP_873980.1 33152627 1491453 1310704..1311636 1 NC_002940.2 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 1311636 nlpI 1491453 nlpI Haemophilus ducreyi 35000HP lipoprotein NlpI NP_873980.1 1310704 D 233412 CDS NP_873981.1 33152628 1491454 1311864..1313684 1 NC_002940.2 cold-shock DEAD box protein-A; ATP-dependent RNA helicase 1313684 deaD 1491454 deaD Haemophilus ducreyi 35000HP ATP-dependent RNA helicase NP_873981.1 1311864 D 233412 CDS NP_873982.1 33152629 1491455 1313738..1314289 1 NC_002940.2 hypothetical protein 1314289 1491455 HD1591 Haemophilus ducreyi 35000HP hypothetical protein NP_873982.1 1313738 D 233412 CDS NP_873983.1 33152630 1491456 complement(1314325..1314894) 1 NC_002940.2 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 1314894 1491456 HD1592 Haemophilus ducreyi 35000HP glutamine amidotransferase subunit PdxT NP_873983.1 1314325 R 233412 CDS NP_873984.1 33152631 1491457 complement(1314894..1315781) 1 NC_002940.2 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 1315781 1491457 HD1593 Haemophilus ducreyi 35000HP pyridoxal biosynthesis lyase PdxS NP_873984.1 1314894 R 233412 CDS NP_873985.1 33152632 1491458 1315881..1315994 1 NC_002940.2 hypothetical protein 1315994 1491458 HD1594 Haemophilus ducreyi 35000HP hypothetical protein NP_873985.1 1315881 D 233412 CDS NP_873986.1 33152633 1491459 1315981..1317282 1 NC_002940.2 GntR family transcriptional regulator 1317282 1491459 HD1595 Haemophilus ducreyi 35000HP GntR family transcriptional regulator NP_873986.1 1315981 D 233412 CDS NP_873987.1 33152634 1491460 complement(1317344..1317901) 1 NC_002940.2 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1317901 frr 1491460 frr Haemophilus ducreyi 35000HP ribosome recycling factor NP_873987.1 1317344 R 233412 CDS NP_873988.1 33152635 1491461 complement(1318115..1318828) 1 NC_002940.2 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1318828 pyrH 1491461 pyrH Haemophilus ducreyi 35000HP uridylate kinase NP_873988.1 1318115 R 233412 CDS NP_873989.1 33152636 1491462 1318942..1320525 1 NC_002940.2 hypothetical protein 1320525 1491462 HD1598 Haemophilus ducreyi 35000HP hypothetical protein NP_873989.1 1318942 D 233412 CDS NP_873990.1 33152637 1491463 complement(1320591..1321442) 1 NC_002940.2 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1321442 tsf 1491463 tsf Haemophilus ducreyi 35000HP elongation factor Ts NP_873990.1 1320591 R 233412 CDS NP_873991.1 33152638 1491464 complement(1321542..1322258) 1 NC_002940.2 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1322258 rpsB 1491464 rpsB Haemophilus ducreyi 35000HP 30S ribosomal protein S2 NP_873991.1 1321542 R 233412 CDS NP_873992.1 33152639 1491465 complement(1322581..1324056) 1 NC_002940.2 hypothetical protein 1324056 1491465 HD1601 Haemophilus ducreyi 35000HP hypothetical protein NP_873992.1 1322581 R 233412 CDS NP_873993.1 33152640 1491467 complement(1325435..1326157) 1 NC_002940.2 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 1326157 recO 1491467 recO Haemophilus ducreyi 35000HP DNA repair protein RecO NP_873993.1 1325435 R 233412 CDS NP_873994.1 33152641 1491468 complement(1326173..1327087) 1 NC_002940.2 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1327087 era 1491468 era Haemophilus ducreyi 35000HP GTP-binding protein Era NP_873994.1 1326173 R 233412 CDS NP_873995.1 33152642 1491469 complement(1327164..1327832) 1 NC_002940.2 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1327832 rnc 1491469 rnc Haemophilus ducreyi 35000HP ribonuclease III NP_873995.1 1327164 R 233412 CDS NP_873996.1 33152643 1491470 complement(1327844..1328803) 1 NC_002940.2 signal peptidase I; SPase I 1328803 lepB 1491470 lepB Haemophilus ducreyi 35000HP SPase I NP_873996.1 1327844 R 233412 CDS NP_873997.1 33152644 1491471 complement(1328888..1330687) 1 NC_002940.2 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1330687 lepA 1491471 lepA Haemophilus ducreyi 35000HP GTP-binding protein LepA NP_873997.1 1328888 R 233412 CDS NP_873998.1 33152645 1491472 1330900..1331271 1 NC_002940.2 hypothetical protein 1331271 1491472 HD1609 Haemophilus ducreyi 35000HP hypothetical protein NP_873998.1 1330900 D 233412 CDS NP_873999.1 33152646 1491473 complement(1331135..1331338) 1 NC_002940.2 hypothetical protein 1331338 1491473 HD1610 Haemophilus ducreyi 35000HP hypothetical protein NP_873999.1 1331135 R 233412 CDS NP_874000.1 33152647 1491474 complement(1331323..1331763) 1 NC_002940.2 hypothetical protein 1331763 1491474 HD1611 Haemophilus ducreyi 35000HP hypothetical protein NP_874000.1 1331323 R 233412 CDS NP_874001.1 33152648 1491475 complement(1331754..1332791) 1 NC_002940.2 transposase 1332791 1491475 HD1612 Haemophilus ducreyi 35000HP transposase NP_874001.1 1331754 R 233412 CDS NP_874002.1 33152649 1491476 1332901..1333236 1 NC_002940.2 hypothetical protein 1333236 1491476 HD1613 Haemophilus ducreyi 35000HP hypothetical protein NP_874002.1 1332901 D 233412 CDS NP_874003.1 33152650 1491477 1333199..1333597 1 NC_002940.2 prophage ps3 protein01-like protein 1333597 1491477 HD1614 Haemophilus ducreyi 35000HP prophage ps3 protein01-like protein NP_874003.1 1333199 D 233412 CDS NP_874004.1 33152651 1491478 1333657..1333854 1 NC_002940.2 hypothetical protein 1333854 1491478 HD1615 Haemophilus ducreyi 35000HP hypothetical protein NP_874004.1 1333657 D 233412 CDS NP_874005.1 33152652 1491479 1334298..1335362 1 NC_002940.2 transposase 1335362 1491479 HD1616 Haemophilus ducreyi 35000HP transposase NP_874005.1 1334298 D 233412 CDS NP_874006.1 33152653 1491480 1335375..1335755 1 NC_002940.2 hypothetical protein 1335755 1491480 HD1617 Haemophilus ducreyi 35000HP hypothetical protein NP_874006.1 1335375 D 233412 CDS NP_874007.1 33152654 1491481 1335789..1336304 1 NC_002940.2 hypothetical protein 1336304 1491481 HD1618 Haemophilus ducreyi 35000HP hypothetical protein NP_874007.1 1335789 D 233412 CDS NP_874008.1 33152655 1491482 complement(1336482..1337930) 1 NC_002940.2 sodium/alanine symporter 1337930 1491482 HD1619 Haemophilus ducreyi 35000HP sodium/alanine symporter NP_874008.1 1336482 R 233412 CDS NP_874009.1 33152656 1491483 complement(1338012..1339004) 1 NC_002940.2 hypothetical protein 1339004 1491483 HD1621 Haemophilus ducreyi 35000HP hypothetical protein NP_874009.1 1338012 R 233412 CDS NP_874010.1 33152657 1491484 complement(1338995..1339639) 1 NC_002940.2 hypothetical protein 1339639 1491484 HD1622 Haemophilus ducreyi 35000HP hypothetical protein NP_874010.1 1338995 R 233412 CDS NP_874011.1 33152658 1491487 complement(1340628..1342052) 1 NC_002940.2 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1342052 lpdA 1491487 lpdA Haemophilus ducreyi 35000HP dihydrolipoamide dehydrogenase NP_874011.1 1340628 R 233412 CDS NP_874012.1 33152659 1491488 complement(1342118..1343689) 1 NC_002940.2 dihydrolipoamide acetyltransferase 1343689 aceF 1491488 aceF Haemophilus ducreyi 35000HP dihydrolipoamide acetyltransferase NP_874012.1 1342118 R 233412 CDS NP_874013.1 33152660 1491489 complement(1343768..1346425) 1 NC_002940.2 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 1346425 aceE 1491489 aceE Haemophilus ducreyi 35000HP pyruvate dehydrogenase subunit E1 NP_874013.1 1343768 R 233412 CDS NP_874014.1 33152661 1491490 complement(1346764..1347771) 1 NC_002940.2 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1347771 pyrD 1491490 pyrD Haemophilus ducreyi 35000HP dihydroorotate dehydrogenase 2 NP_874014.1 1346764 R 233412 CDS NP_874015.1 33152662 1491491 complement(1347890..1348840) 1 NC_002940.2 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1348840 prsA 1491491 prsA Haemophilus ducreyi 35000HP ribose-phosphate pyrophosphokinase NP_874015.1 1347890 R 233412 CDS NP_874016.1 33152663 1491492 complement(1348871..1349719) 1 NC_002940.2 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1349719 ipk 1491492 ipk Haemophilus ducreyi 35000HP 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase NP_874016.1 1348871 R 233412 CDS NP_874017.1 33152664 1491493 complement(1349720..1350349) 1 NC_002940.2 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 1350349 lolB 1491493 lolB Haemophilus ducreyi 35000HP outer membrane lipoprotein LolB NP_874017.1 1349720 R 233412 CDS NP_874018.1 33152665 1491494 complement(1350494..1352242) 1 NC_002940.2 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 1352242 msbA 1491494 msbA Haemophilus ducreyi 35000HP lipid transporter ATP-binding/permease NP_874018.1 1350494 R 233412 CDS NP_874019.1 33152666 1491495 complement(1352312..1353784) 1 NC_002940.2 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 1353784 cafA 1491495 cafA Haemophilus ducreyi 35000HP ribonuclease G NP_874019.1 1352312 R 233412 CDS NP_874020.1 33152667 1491496 1354078..1355040 1 NC_002940.2 hypothetical protein 1355040 1491496 HD1632 Haemophilus ducreyi 35000HP hypothetical protein NP_874020.1 1354078 D 233412 CDS NP_874021.1 33152668 1491497 1355068..1355415 1 NC_002940.2 hypothetical protein 1355415 1491497 HD1634 Haemophilus ducreyi 35000HP hypothetical protein NP_874021.1 1355068 D 233412 CDS NP_874022.1 33152669 1491498 1355283..1355405 1 NC_002940.2 hypothetical protein 1355405 1491498 HD1633 Haemophilus ducreyi 35000HP hypothetical protein NP_874022.1 1355283 D 233412 CDS NP_874023.1 33152670 1491499 complement(1355481..1356587) 1 NC_002940.2 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 1356587 mltA 1491499 mltA Haemophilus ducreyi 35000HP murein transglycosylase A NP_874023.1 1355481 R 233412 CDS NP_874024.1 33152671 1491503 1359265..1360473 1 NC_002940.2 hypothetical protein 1360473 1491503 HD1639 Haemophilus ducreyi 35000HP hypothetical protein NP_874024.1 1359265 D 233412 CDS NP_874025.1 33152672 1491504 complement(1360475..1360696) 1 NC_002940.2 hypothetical protein 1360696 1491504 HD1640 Haemophilus ducreyi 35000HP hypothetical protein NP_874025.1 1360475 R 233412 CDS NP_874026.1 33152673 1491505 1361011..1362030 1 NC_002940.2 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1362030 purR 1491505 purR Haemophilus ducreyi 35000HP DNA-binding transcriptional repressor PurR NP_874026.1 1361011 D 233412 CDS NP_874027.1 33152674 1491506 1362033..1362638 1 NC_002940.2 DedA family integral membrane protein 1362638 1491506 HD1642 Haemophilus ducreyi 35000HP DedA family integral membrane protein NP_874027.1 1362033 D 233412 CDS NP_874028.1 33152675 1491507 complement(1362720..1365152) 1 NC_002940.2 Type II topoisomerase; DNA gyrase subunit B 1365152 gyrB 1491507 gyrB Haemophilus ducreyi 35000HP DNA gyrase subunit B NP_874028.1 1362720 R 233412 CDS NP_874029.1 33152676 1491508 1365131..1365325 1 NC_002940.2 hypothetical protein 1365325 1491508 HD1644 Haemophilus ducreyi 35000HP hypothetical protein NP_874029.1 1365131 D 233412 CDS NP_874030.1 33152677 1491509 complement(1365248..1365364) 1 NC_002940.2 hypothetical protein 1365364 1491509 HD1645 Haemophilus ducreyi 35000HP hypothetical protein NP_874030.1 1365248 R 233412 CDS NP_874031.1 33152678 1491510 1365322..1365444 1 NC_002940.2 hypothetical protein 1365444 1491510 HD1646 Haemophilus ducreyi 35000HP hypothetical protein NP_874031.1 1365322 D 233412 CDS NP_874032.1 33152679 1491511 complement(1365484..1366317) 1 NC_002940.2 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 1366317 ubiA 1491511 ubiA Haemophilus ducreyi 35000HP 4-hydroxybenzoate octaprenyltransferase NP_874032.1 1365484 R 233412 CDS NP_874033.1 33152680 1491512 complement(1366367..1367128) 1 NC_002940.2 glycerol-3-phosphate regulon repressor 1367128 glpR 1491512 glpR Haemophilus ducreyi 35000HP glycerol-3-phosphate regulon repressor NP_874033.1 1366367 R 233412 CDS NP_874034.1 33152681 1491513 complement(1367205..1368572) 1 NC_002940.2 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1368572 purB 1491513 purB Haemophilus ducreyi 35000HP adenylosuccinate lyase NP_874034.1 1367205 R 233412 CDS NP_874035.1 33152682 1491514 complement(1368614..1369261) 1 NC_002940.2 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1369261 1491514 HD1650 Haemophilus ducreyi 35000HP hypothetical protein NP_874035.1 1368614 R 233412 CDS NP_874036.1 33152683 1491515 complement(1369377..1371050) 1 NC_002940.2 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1371050 cydC 1491515 cydC Haemophilus ducreyi 35000HP cysteine/glutathione ABC transporter membrane/ATP-binding protein NP_874036.1 1369377 R 233412 CDS NP_874037.1 33152684 1491516 complement(1371089..1372828) 1 NC_002940.2 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1372828 cydD 1491516 cydD Haemophilus ducreyi 35000HP cysteine/glutathione ABC transporter membrane/ATP-binding protein NP_874037.1 1371089 R 233412 CDS NP_874038.1 33152685 1491517 complement(1372845..1372991) 1 NC_002940.2 hypothetical protein 1372991 1491517 HD1653 Haemophilus ducreyi 35000HP hypothetical protein NP_874038.1 1372845 R 233412 CDS NP_874039.1 33152686 1491518 complement(1372978..1376931) 1 NC_002940.2 hypothetical protein 1376931 1491518 HD1654 Haemophilus ducreyi 35000HP hypothetical protein NP_874039.1 1372978 R 233412 CDS NP_874040.1 33152687 1491519 complement(1376947..1378755) 1 NC_002940.2 hypothetical protein 1378755 1491519 HD1655 Haemophilus ducreyi 35000HP hypothetical protein NP_874040.1 1376947 R 233412 CDS NP_874041.1 33152688 1491521 complement(1379662..1380897) 1 NC_002940.2 hypothetical protein 1380897 1491521 HD1658 Haemophilus ducreyi 35000HP hypothetical protein NP_874041.1 1379662 R 233412 CDS NP_874042.1 33152689 1491522 1381058..1381741 1 NC_002940.2 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1381741 gpmA 1491522 gpmA Haemophilus ducreyi 35000HP phosphoglyceromutase NP_874042.1 1381058 D 233412 CDS NP_874043.1 33152690 1491523 1381939..1382592 1 NC_002940.2 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1382592 udk 1491523 udk Haemophilus ducreyi 35000HP uridine kinase NP_874043.1 1381939 D 233412 CDS NP_874044.1 33152691 1491524 1382601..1383185 1 NC_002940.2 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 1383185 dcd 1491524 dcd Haemophilus ducreyi 35000HP deoxycytidine triphosphate deaminase NP_874044.1 1382601 D 233412 CDS NP_874045.1 33152692 1491525 complement(1383308..1384756) 1 NC_002940.2 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 1384756 pntB 1491525 pntB Haemophilus ducreyi 35000HP pyridine nucleotide transhydrogenase NP_874045.1 1383308 R 233412 CDS NP_874046.1 33152693 1491526 complement(1384769..1386304) 1 NC_002940.2 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 1386304 pntA 1491526 pntA Haemophilus ducreyi 35000HP NAD(P) transhydrogenase subunit alpha NP_874046.1 1384769 R 233412 CDS NP_874047.1 33152694 1491527 1386544..1387272 1 NC_002940.2 tRNA/rRNA methyltransferase 1387272 1491527 HD1664 Haemophilus ducreyi 35000HP tRNA/rRNA methyltransferase NP_874047.1 1386544 D 233412 CDS NP_874048.1 33152695 1491528 complement(1387399..1388238) 1 NC_002940.2 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1388238 queF 1491528 queF Haemophilus ducreyi 35000HP 7-cyano-7-deazaguanine reductase NP_874048.1 1387399 R 233412 CDS NP_874049.1 33152696 1491529 complement(1388251..1388799) 1 NC_002940.2 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 1388799 1491529 HD1666 Haemophilus ducreyi 35000HP D,D-heptose 1,7-bisphosphate phosphatase NP_874049.1 1388251 R 233412 CDS NP_874050.1 33152697 1491530 complement(1388799..1389269) 1 NC_002940.2 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 1389269 bcp 1491530 bcp Haemophilus ducreyi 35000HP thioredoxin-dependent thiol peroxidase NP_874050.1 1388799 R 233412 CDS NP_874051.1 33152698 1491531 complement(1389341..1390525) 1 NC_002940.2 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1390525 1491531 HD1668 Haemophilus ducreyi 35000HP coproporphyrinogen III oxidase NP_874051.1 1389341 R 233412 CDS NP_874052.1 33152699 1491532 1390763..1392340 1 NC_002940.2 ABC transporter substrate-binding protein 1392340 1491532 HD1669 Haemophilus ducreyi 35000HP ABC transporter substrate-binding protein NP_874052.1 1390763 D 233412 CDS NP_874053.1 33152700 1491533 1392558..1393511 1 NC_002940.2 ABC transporter permease 1393511 1491533 HD1670 Haemophilus ducreyi 35000HP ABC transporter permease NP_874053.1 1392558 D 233412 CDS NP_874054.1 33152701 1491534 1393511..1395466 1 NC_002940.2 ABC transporter ATPase and permease 1395466 1491534 HD1671 Haemophilus ducreyi 35000HP ABC transporter ATPase and permease NP_874054.1 1393511 D 233412 CDS NP_874055.1 33152702 1491535 1395496..1396302 1 NC_002940.2 ABC transporter ATP-binding protein 1396302 1491535 HD1672 Haemophilus ducreyi 35000HP ABC transporter ATP-binding protein NP_874055.1 1395496 D 233412 CDS NP_874056.1 33152703 1491537 complement(1398421..1399287) 1 NC_002940.2 integral membrane protein 1399287 1491537 HD1678 Haemophilus ducreyi 35000HP integral membrane protein NP_874056.1 1398421 R 233412 CDS NP_874057.1 33152704 1491538 complement(1399426..1399959) 1 NC_002940.2 hypothetical protein 1399959 1491538 HD1679 Haemophilus ducreyi 35000HP hypothetical protein NP_874057.1 1399426 R 233412 CDS NP_874058.1 33152705 1491539 complement(1399956..1400591) 1 NC_002940.2 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1400591 bioD 1491539 bioD Haemophilus ducreyi 35000HP dithiobiotin synthetase NP_874058.1 1399956 R 233412 CDS NP_874059.1 33152706 1491540 complement(1400584..1401360) 1 NC_002940.2 biotin synthesis protein 1401360 bioC 1491540 bioC Haemophilus ducreyi 35000HP biotin synthesis protein NP_874059.1 1400584 R 233412 CDS NP_874060.1 33152707 1491541 complement(1401348..1402016) 1 NC_002940.2 hypothetical protein 1402016 1491541 HD1682 Haemophilus ducreyi 35000HP hypothetical protein NP_874060.1 1401348 R 233412 CDS NP_874061.1 33152708 1491542 complement(1402029..1403192) 1 NC_002940.2 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 1403192 bioF 1491542 bioF Haemophilus ducreyi 35000HP 8-amino-7-oxononanoate synthase NP_874061.1 1402029 R 233412 CDS NP_874062.1 33152709 1491543 complement(1403276..1404589) 1 NC_002940.2 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 1404589 bioA 1491543 bioA Haemophilus ducreyi 35000HP adenosylmethionine-8-amino-7-oxononanoate aminotransferase NP_874062.1 1403276 R 233412 CDS NP_874063.1 33152710 1491544 1404680..1405624 1 NC_002940.2 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1405624 1491544 HD1686 Haemophilus ducreyi 35000HP N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase NP_874063.1 1404680 D 233412 CDS NP_874064.1 33152711 1491545 complement(1405599..1405703) 1 NC_002940.2 hypothetical protein 1405703 1491545 HD1687 Haemophilus ducreyi 35000HP hypothetical protein NP_874064.1 1405599 R 233412 CDS NP_874065.1 33152712 1491546 complement(1405788..1406279) 1 NC_002940.2 hypothetical protein 1406279 1491546 HD1688 Haemophilus ducreyi 35000HP hypothetical protein NP_874065.1 1405788 R 233412 CDS NP_874066.1 33152713 1491547 complement(1406296..1407387) 1 NC_002940.2 transposase 1407387 1491547 HD1689 Haemophilus ducreyi 35000HP transposase NP_874066.1 1406296 R 233412 CDS NP_874067.1 33152714 1491548 complement(1407737..1410367) 1 NC_002940.2 type III restriction enzyme 1410367 1491548 HD1690 Haemophilus ducreyi 35000HP type III restriction enzyme NP_874067.1 1407737 R 233412 CDS NP_874068.1 33152715 1491550 complement(1412498..1412833) 1 NC_002940.2 hypothetical protein 1412833 1491550 HD1694 Haemophilus ducreyi 35000HP hypothetical protein NP_874068.1 1412498 R 233412 CDS NP_874069.1 33152716 1491551 1412935..1413402 1 NC_002940.2 transposase 1413402 1491551 HD1695 Haemophilus ducreyi 35000HP transposase NP_874069.1 1412935 D 233412 CDS NP_874070.1 33152717 1491552 1413380..1413973 1 NC_002940.2 hypothetical protein 1413973 1491552 HD1696 Haemophilus ducreyi 35000HP hypothetical protein NP_874070.1 1413380 D 233412 CDS NP_874071.1 33152718 1491553 1413982..1414404 1 NC_002940.2 hypothetical protein 1414404 1491553 HD1697 Haemophilus ducreyi 35000HP hypothetical protein NP_874071.1 1413982 D 233412 CDS NP_874072.1 33152719 1491554 complement(1414433..1414909) 1 NC_002940.2 hypothetical protein 1414909 1491554 HD1698 Haemophilus ducreyi 35000HP hypothetical protein NP_874072.1 1414433 R 233412 CDS NP_874073.1 33152720 1491555 complement(1415040..1415516) 1 NC_002940.2 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1415516 greA 1491555 greA Haemophilus ducreyi 35000HP transcription elongation factor GreA NP_874073.1 1415040 R 233412 CDS NP_874074.1 33152721 1491557 1417347..1418735 1 NC_002940.2 bifunctional purine biosynthesis protein, N-terminal truncated 1418735 purH 1491557 purH Haemophilus ducreyi 35000HP bifunctional purine biosynthesis protein, N-terminal truncated NP_874074.1 1417347 D 233412 CDS NP_874075.1 33152722 1491558 complement(1418783..1421122) 1 NC_002940.2 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 1421122 imp 1491558 imp Haemophilus ducreyi 35000HP organic solvent tolerance protein NP_874075.1 1418783 R 233412 CDS NP_874076.1 33152723 1491559 complement(1421191..1421661) 1 NC_002940.2 coproporphyrinogen III oxidase 1421661 1491559 HD1705 Haemophilus ducreyi 35000HP coproporphyrinogen III oxidase NP_874076.1 1421191 R 233412 CDS NP_874077.1 33152724 1491560 complement(1421678..1422262) 1 NC_002940.2 hypothetical protein 1422262 1491560 HD1706 Haemophilus ducreyi 35000HP hypothetical protein NP_874077.1 1421678 R 233412 CDS NP_874078.1 33152725 1491561 1422527..1423747 1 NC_002940.2 sodium/glutamate symporter 1423747 gltS 1491561 gltS Haemophilus ducreyi 35000HP sodium/glutamate symporter NP_874078.1 1422527 D 233412 CDS NP_874079.1 33152726 1491562 complement(1423816..1424193) 1 NC_002940.2 hypothetical protein 1424193 1491562 HD1708 Haemophilus ducreyi 35000HP hypothetical protein NP_874079.1 1423816 R 233412 CDS NP_874080.1 33152727 1491563 complement(1424289..1427162) 1 NC_002940.2 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 1427162 glnE 1491563 glnE Haemophilus ducreyi 35000HP bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase NP_874080.1 1424289 R 233412 CDS NP_874081.1 33152728 1491564 complement(1427224..1427505) 1 NC_002940.2 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein 1427505 1491564 HD1710 Haemophilus ducreyi 35000HP hypothetical protein NP_874081.1 1427224 R 233412 CDS NP_874082.1 33152729 1491565 complement(1427542..1428012) 1 NC_002940.2 acyl CoA thioester hydrolase 1428012 1491565 HD1711 Haemophilus ducreyi 35000HP acyl CoA thioester hydrolase NP_874082.1 1427542 R 233412 CDS NP_874083.1 33152730 1491566 complement(1427999..1428550) 1 NC_002940.2 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1428550 ispZ 1491566 ispZ Haemophilus ducreyi 35000HP intracellular septation protein A NP_874083.1 1427999 R 233412 CDS NP_874084.1 33152731 1491567 complement(1428552..1429298) 1 NC_002940.2 hypothetical protein 1429298 1491567 HD1713 Haemophilus ducreyi 35000HP hypothetical protein NP_874084.1 1428552 R 233412 CDS NP_874085.1 33152732 1491568 1429353..1429454 1 NC_002940.2 hypothetical protein 1429454 1491568 HD1714 Haemophilus ducreyi 35000HP hypothetical protein NP_874085.1 1429353 D 233412 CDS NP_874086.1 33152733 1491569 1429435..1429881 1 NC_002940.2 hypothetical protein 1429881 1491569 HD1715 Haemophilus ducreyi 35000HP hypothetical protein NP_874086.1 1429435 D 233412 CDS NP_874087.1 33152734 1491570 1429947..1430978 1 NC_002940.2 ATPase 1430978 1491570 HD1716 Haemophilus ducreyi 35000HP ATPase NP_874087.1 1429947 D 233412 CDS NP_874088.1 33152735 1491571 1431168..1432544 1 NC_002940.2 transporter 1432544 1491571 HD1717 Haemophilus ducreyi 35000HP transporter NP_874088.1 1431168 D 233412 CDS NP_874089.1 33152736 1491572 1432567..1433370 1 NC_002940.2 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1433370 xthA 1491572 xthA Haemophilus ducreyi 35000HP exonuclease III NP_874089.1 1432567 D 233412 CDS NP_874090.1 33152737 1491573 complement(1433385..1434416) 1 NC_002940.2 lipooligosaccharide D-glycero-D-manno-heptosyltransferase 1434416 lbgB 1491573 lbgB Haemophilus ducreyi 35000HP lipooligosaccharide D-glycero-D-manno-heptosyltransferase NP_874090.1 1433385 R 233412 CDS NP_874091.1 33152738 1491574 complement(1434417..1435091) 1 NC_002940.2 lipooligosaccharide galactosyltransferase I 1435091 lbgA 1491574 lbgA Haemophilus ducreyi 35000HP lipooligosaccharide galactosyltransferase I NP_874091.1 1434417 R 233412 CDS NP_874092.1 33152739 1491575 complement(1435177..1435389) 1 NC_002940.2 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1435389 rpmE 1491575 rpmE Haemophilus ducreyi 35000HP 50S ribosomal protein L31 NP_874092.1 1435177 R 233412 CDS NP_874093.1 33152740 1491576 1435764..1437761 1 NC_002940.2 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1437761 tktA 1491576 tktA Haemophilus ducreyi 35000HP transketolase NP_874093.1 1435764 D 233412 CDS NP_874094.1 33152741 1491578 complement(1438895..1439641) 1 NC_002940.2 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1439641 fadR 1491578 fadR Haemophilus ducreyi 35000HP fatty acid metabolism regulator NP_874094.1 1438895 R 233412 CDS NP_874095.1 33152742 1491579 1439798..1441339 1 NC_002940.2 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1441339 nhaB 1491579 nhaB Haemophilus ducreyi 35000HP sodium/proton antiporter NP_874095.1 1439798 D 233412 CDS NP_874096.1 33152743 1491580 1441450..1441989 1 NC_002940.2 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1441989 dsbB 1491580 dsbB Haemophilus ducreyi 35000HP disulfide bond formation protein B NP_874096.1 1441450 D 233412 CDS NP_874097.1 33152744 1491581 complement(1442082..1442174) 1 NC_002940.2 hypothetical protein 1442174 1491581 HD1730 Haemophilus ducreyi 35000HP hypothetical protein NP_874097.1 1442082 R 233412 CDS NP_874098.1 33152745 1491582 1442319..1444589 1 NC_002940.2 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1444589 nrdA 1491582 nrdA Haemophilus ducreyi 35000HP ribonucleotide-diphosphate reductase subunit alpha NP_874098.1 1442319 D 233412 CDS NP_874099.1 33152746 1491583 1444741..1445871 1 NC_002940.2 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 1445871 nrdB 1491583 nrdB Haemophilus ducreyi 35000HP ribonucleotide-diphosphate reductase subunit beta NP_874099.1 1444741 D 233412 CDS NP_874100.1 33152747 1491584 complement(1445868..1445966) 1 NC_002940.2 hypothetical protein 1445966 1491584 HD1733 Haemophilus ducreyi 35000HP hypothetical protein NP_874100.1 1445868 R 233412 CDS NP_874101.1 33152748 1491585 complement(1445972..1447069) 1 NC_002940.2 ATPase 1447069 mrp 1491585 mrp Haemophilus ducreyi 35000HP ATPase NP_874101.1 1445972 R 233412 CDS NP_874102.1 33152749 1491586 complement(1447073..1448596) 1 NC_002940.2 oligopeptide transporter periplasmic-binding protein 1448596 1491586 HD1735 Haemophilus ducreyi 35000HP oligopeptide transporter periplasmic-binding protein NP_874102.1 1447073 R 233412 CDS NP_874103.1 33152750 1491587 complement(1448606..1449253) 1 NC_002940.2 hypothetical protein 1449253 1491587 HD1736 Haemophilus ducreyi 35000HP hypothetical protein NP_874103.1 1448606 R 233412 CDS NP_874104.1 33152751 1491588 complement(1449373..1451235) 1 NC_002940.2 peptidyl-prolyl cis-trans isomerase D 1451235 ppiD 1491588 ppiD Haemophilus ducreyi 35000HP peptidyl-prolyl cis-trans isomerase D NP_874104.1 1449373 R 233412 CDS NP_874105.1 33152752 1491589 1451444..1451713 1 NC_002940.2 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1451713 rpsO 1491589 rpsO Haemophilus ducreyi 35000HP 30S ribosomal protein S15 NP_874105.1 1451444 D 233412 CDS NP_874106.1 33152753 1491590 1451740..1451853 1 NC_002940.2 hypothetical protein 1451853 1491590 HD1739 Haemophilus ducreyi 35000HP hypothetical protein NP_874106.1 1451740 D 233412 CDS NP_874107.1 33152754 1491591 complement(1451828..1453069) 1 NC_002940.2 HemY protein 1453069 hemY 1491591 hemY Haemophilus ducreyi 35000HP HemY protein NP_874107.1 1451828 R 233412 CDS NP_874108.1 33152755 1491592 complement(1453079..1454473) 1 NC_002940.2 uroporphyrinogen III C-methyltransferase 1454473 hemX 1491592 hemX Haemophilus ducreyi 35000HP uroporphyrinogen III C-methyltransferase NP_874108.1 1453079 R 233412 CDS NP_874109.1 33152756 1491593 complement(1454483..1455238) 1 NC_002940.2 uroporphyrinogen III synthase 1455238 hemD 1491593 hemD Haemophilus ducreyi 35000HP uroporphyrinogen III synthase NP_874109.1 1454483 R 233412 CDS NP_874110.1 33152757 1491594 complement(1455538..1456302) 1 NC_002940.2 hypothetical protein 1456302 1491594 HD1744 Haemophilus ducreyi 35000HP hypothetical protein NP_874110.1 1455538 R 233412 CDS NP_874111.1 33152758 1491595 complement(1456343..1458280) 1 NC_002940.2 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1458280 uup 1491595 uup Haemophilus ducreyi 35000HP ABC transporter ATPase NP_874111.1 1456343 R 233412 CDS NP_874112.1 33152759 1491596 1458274..1458366 1 NC_002940.2 hypothetical protein 1458366 1491596 HD1746 Haemophilus ducreyi 35000HP hypothetical protein NP_874112.1 1458274 D 233412 CDS NP_874113.1 33152760 1491597 complement(1458363..1458476) 1 NC_002940.2 hypothetical protein 1458476 1491597 HD1747 Haemophilus ducreyi 35000HP hypothetical protein NP_874113.1 1458363 R 233412 CDS NP_874114.1 33152761 1491598 complement(1458547..1461249) 1 NC_002940.2 DNA gyrase subunit A 1461249 gyrA 1491598 gyrA Haemophilus ducreyi 35000HP DNA gyrase subunit A NP_874114.1 1458547 R 233412 CDS NP_874115.1 33152762 1491599 complement(1461363..1461743) 1 NC_002940.2 hypothetical protein 1461743 1491599 HD1749 Haemophilus ducreyi 35000HP hypothetical protein NP_874115.1 1461363 R 233412 CDS NP_874116.1 33152763 1491600 1461807..1462517 1 NC_002940.2 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 1462517 ubiG 1491600 ubiG Haemophilus ducreyi 35000HP 3-demethylubiquinone-9 3-methyltransferase NP_874116.1 1461807 D 233412 CDS NP_874117.1 33152764 1491601 1462631..1462927 1 NC_002940.2 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1462927 yajC 1491601 yajC Haemophilus ducreyi 35000HP preprotein translocase subunit YajC NP_874117.1 1462631 D 233412 CDS NP_874118.1 33152765 1491602 1462952..1464796 1 NC_002940.2 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1464796 secD 1491602 secD Haemophilus ducreyi 35000HP preprotein translocase subunit SecD NP_874118.1 1462952 D 233412 CDS NP_874119.1 33152766 1491603 1464807..1465781 1 NC_002940.2 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1465781 secF 1491603 secF Haemophilus ducreyi 35000HP preprotein translocase subunit SecF NP_874119.1 1464807 D 233412 CDS NP_874120.1 33152767 1491604 1465934..1466440 1 NC_002940.2 ferritin 1466440 ftnA 1491604 ftnA Haemophilus ducreyi 35000HP ferritin NP_874120.1 1465934 D 233412 CDS NP_874121.1 33152768 1491605 1466440..1466928 1 NC_002940.2 ferritin 1466928 ftnB 1491605 ftnB Haemophilus ducreyi 35000HP ferritin NP_874121.1 1466440 D 233412 CDS NP_874122.1 33152769 1491606 1467091..1468392 1 NC_002940.2 xanthine/uracil permease 1468392 1491606 HD1756 Haemophilus ducreyi 35000HP xanthine/uracil permease NP_874122.1 1467091 D 233412 CDS NP_874123.1 33152770 1491607 complement(1468473..1469477) 1 NC_002940.2 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1469477 ruvB 1491607 ruvB Haemophilus ducreyi 35000HP Holliday junction DNA helicase RuvB NP_874123.1 1468473 R 233412 CDS NP_874124.1 33152771 1491608 complement(1469533..1470138) 1 NC_002940.2 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1470138 ruvA 1491608 ruvA Haemophilus ducreyi 35000HP Holliday junction DNA helicase RuvA NP_874124.1 1469533 R 233412 CDS NP_874125.1 33152772 1491609 complement(1470299..1470940) 1 NC_002940.2 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1470940 pyrE 1491609 pyrE Haemophilus ducreyi 35000HP orotate phosphoribosyltransferase NP_874125.1 1470299 R 233412 CDS NP_874126.1 33152773 1491610 complement(1471043..1471885) 1 NC_002940.2 hypothetical protein 1471885 1491610 HD1760 Haemophilus ducreyi 35000HP hypothetical protein NP_874126.1 1471043 R 233412 CDS NP_874127.1 33152774 1491611 1471965..1472516 1 NC_002940.2 N-acetyl-anhydromuranmyl-L-alanine amidase 1472516 ampD 1491611 ampD Haemophilus ducreyi 35000HP N-acetyl-anhydromuranmyl-L-alanine amidase NP_874127.1 1471965 D 233412 CDS NP_874128.1 33152775 1491612 complement(1472701..1473369) 1 NC_002940.2 ribosomal large subunit pseudouridine synthase A; pseudouridylate synthase 1473369 rluA 1491612 rluA Haemophilus ducreyi 35000HP pseudouridylate synthase NP_874128.1 1472701 R 233412 CDS NP_874129.1 33152776 1491613 complement(1473426..1476347) 1 NC_002940.2 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 1476347 hepA 1491613 hepA Haemophilus ducreyi 35000HP ATP-dependent helicase HepA NP_874129.1 1473426 R 233412 CDS NP_874130.1 33152777 1491614 1476563..1477891 1 NC_002940.2 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 1477891 rumA 1491614 rumA Haemophilus ducreyi 35000HP 23S rRNA 5-methyluridine methyltransferase NP_874130.1 1476563 D 233412 CDS NP_874131.1 33152778 1491615 complement(1478188..1478937) 1 NC_002940.2 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 1478937 moeB 1491615 moeB Haemophilus ducreyi 35000HP molybdopterin biosynthesis protein MoeB NP_874131.1 1478188 R 233412 CDS NP_874132.1 33152779 1491616 complement(1478937..1480166) 1 NC_002940.2 molybdopterin biosynthesis protein MoeA 1480166 moeA 1491616 moeA Haemophilus ducreyi 35000HP molybdopterin biosynthesis protein MoeA NP_874132.1 1478937 R 233412 CDS NP_874133.1 33152780 1491617 1480305..1482221 1 NC_002940.2 ABC transporter ATP-binding protein 1482221 1491617 HD1768 Haemophilus ducreyi 35000HP ABC transporter ATP-binding protein NP_874133.1 1480305 D 233412 CDS NP_874134.1 33152781 1491618 complement(1482288..1483313) 1 NC_002940.2 hypothetical protein 1483313 1491618 HD1769 Haemophilus ducreyi 35000HP hypothetical protein NP_874134.1 1482288 R 233412 CDS NP_874135.1 33152782 1491619 complement(1483291..1484268) 1 NC_002940.2 nitrogen regulator protein 1484268 1491619 HD1770 Haemophilus ducreyi 35000HP nitrogen regulator protein NP_874135.1 1483291 R 233412 CDS NP_874136.1 33152783 1491620 complement(1484372..1485232) 1 NC_002940.2 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 1485232 djlA 1491620 djlA Haemophilus ducreyi 35000HP Dna-J like membrane chaperone protein NP_874136.1 1484372 R 233412 CDS NP_874137.1 33152784 1491621 complement(1485449..1485922) 1 NC_002940.2 18K peptidoglycan-associated outer membrane lipoprotein 1485922 pal 1491621 pal Haemophilus ducreyi 35000HP 18K peptidoglycan-associated outer membrane lipoprotein NP_874137.1 1485449 R 233412 CDS NP_874138.1 33152785 1491622 complement(1485947..1487227) 1 NC_002940.2 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 1487227 tolB 1491622 tolB Haemophilus ducreyi 35000HP translocation protein TolB NP_874138.1 1485947 R 233412 CDS NP_874139.1 33152786 1491624 complement(1488372..1488812) 1 NC_002940.2 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 1488812 tolR 1491624 tolR Haemophilus ducreyi 35000HP colicin uptake protein TolR NP_874139.1 1488372 R 233412 CDS NP_874140.1 33152787 1491625 complement(1488881..1489561) 1 NC_002940.2 colicin transport protein, TolQ 1489561 tolQ 1491625 tolQ Haemophilus ducreyi 35000HP colicin transport protein, TolQ NP_874140.1 1488881 R 233412 CDS NP_874141.1 33152788 1491626 complement(1489594..1489983) 1 NC_002940.2 hypothetical protein 1489983 1491626 HD1778 Haemophilus ducreyi 35000HP hypothetical protein NP_874141.1 1489594 R 233412 CDS NP_874142.1 33152789 1491627 complement(1490119..1490409) 1 NC_002940.2 hypothetical protein 1490409 1491627 HD1779 Haemophilus ducreyi 35000HP hypothetical protein NP_874142.1 1490119 R 233412 CDS NP_874143.1 33152790 1491628 complement(1490421..1490519) 1 NC_002940.2 hypothetical protein 1490519 1491628 HD1780 Haemophilus ducreyi 35000HP hypothetical protein NP_874143.1 1490421 R 233412 CDS NP_874144.1 33152791 1491629 complement(1490532..1491668) 1 NC_002940.2 cytochrome D ubiquinol oxidase subunit II 1491668 cydB 1491629 cydB Haemophilus ducreyi 35000HP cytochrome D ubiquinol oxidase subunit II NP_874144.1 1490532 R 233412 CDS NP_874145.1 33152792 1491630 complement(1491681..1493231) 1 NC_002940.2 cytochrome D ubiquinol oxidase, subunit I 1493231 cydA 1491630 cydA Haemophilus ducreyi 35000HP cytochrome D ubiquinol oxidase, subunit I NP_874145.1 1491681 R 233412 CDS NP_874146.1 33152793 1491631 1493687..1494022 1 NC_002940.2 hypothetical protein 1494022 1491631 HD1783 Haemophilus ducreyi 35000HP hypothetical protein NP_874146.1 1493687 D 233412 CDS NP_874147.1 33152794 1491632 complement(1494165..1495808) 1 NC_002940.2 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 1495808 groEL 1491632 groEL Haemophilus ducreyi 35000HP molecular chaperone GroEL NP_874147.1 1494165 R 233412 CDS NP_874148.1 33152795 1491633 complement(1495831..1496121) 1 NC_002940.2 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 1496121 groES 1491633 groES Haemophilus ducreyi 35000HP co-chaperonin GroES NP_874148.1 1495831 R 233412 CDS NP_874149.1 33152796 1491634 complement(1496301..1496699) 1 NC_002940.2 mutator MutT protein; 7,8-dihydro-8-oxoguanine-triphosphatase 1496699 mutT 1491634 mutT Haemophilus ducreyi 35000HP 7,8-dihydro-8-oxoguanine-triphosphatase NP_874149.1 1496301 R 233412 CDS NP_874150.1 33152797 1491635 complement(1496879..1499596) 1 NC_002940.2 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1499596 secA 1491635 secA Haemophilus ducreyi 35000HP preprotein translocase subunit SecA NP_874150.1 1496879 R 233412 CDS NP_874151.1 33152798 1491636 complement(1499683..1500003) 1 NC_002940.2 hypothetical protein 1500003 1491636 HD1789 Haemophilus ducreyi 35000HP hypothetical protein NP_874151.1 1499683 R 233412 CDS NP_874152.1 33152799 1491637 1500116..1500427 1 NC_002940.2 hypothetical protein 1500427 1491637 HD1790 Haemophilus ducreyi 35000HP hypothetical protein NP_874152.1 1500116 D 233412 CDS NP_874153.1 33152800 1491639 complement(1500715..1501026) 1 NC_002940.2 transcriptional regulator, BolA 1501026 bolA 1491639 bolA Haemophilus ducreyi 35000HP transcriptional regulator, BolA NP_874153.1 1500715 R 233412 CDS NP_874154.1 33152801 1491640 1501153..1501743 1 NC_002940.2 lipoprotein 1501743 1491640 HD1792 Haemophilus ducreyi 35000HP lipoprotein NP_874154.1 1501153 D 233412 CDS NP_874155.1 33152802 1491641 1501870..1502601 1 NC_002940.2 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1502601 1491641 HD1793 Haemophilus ducreyi 35000HP 16S ribosomal RNA methyltransferase RsmE NP_874155.1 1501870 D 233412 CDS NP_874156.1 33152803 1491642 1502603..1503163 1 NC_002940.2 hypothetical protein 1503163 1491642 HD1794 Haemophilus ducreyi 35000HP hypothetical protein NP_874156.1 1502603 D 233412 CDS NP_874157.1 33152804 1491643 1503175..1503591 1 NC_002940.2 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1503591 1491643 HD1795 Haemophilus ducreyi 35000HP Holliday junction resolvase-like protein NP_874157.1 1503175 D 233412 CDS NP_874158.1 33152805 1491644 1503575..1503721 1 NC_002940.2 hypothetical protein 1503721 1491644 HD1796 Haemophilus ducreyi 35000HP hypothetical protein NP_874158.1 1503575 D 233412 CDS NP_874159.1 33152806 1491645 1503780..1505069 1 NC_002940.2 hypothetical protein 1505069 1491645 HD1797 Haemophilus ducreyi 35000HP hypothetical protein NP_874159.1 1503780 D 233412 CDS NP_874160.1 33152807 1491646 complement(1505158..1505436) 1 NC_002940.2 hypothetical protein 1505436 1491646 HD1798 Haemophilus ducreyi 35000HP hypothetical protein NP_874160.1 1505158 R 233412 CDS NP_874161.1 33152808 1491647 complement(1505572..1505925) 1 NC_002940.2 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1505925 rplT 1491647 rplT Haemophilus ducreyi 35000HP 50S ribosomal protein L20 NP_874161.1 1505572 R 233412 CDS NP_874162.1 33152809 1491648 complement(1506002..1506199) 1 NC_002940.2 50S ribosomal protein L35 1506199 rpmI 1491648 rpmI Haemophilus ducreyi 35000HP 50S ribosomal protein L35 NP_874162.1 1506002 R 233412 CDS NP_874163.1 33152810 1491649 complement(1506442..1507020) 1 NC_002940.2 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1507020 infC 1491649 infC Haemophilus ducreyi 35000HP translation initiation factor IF-3 NP_874163.1 1506442 R 233412 CDS NP_874164.1 33152811 1491650 complement(1507243..1509174) 1 NC_002940.2 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1509174 thrS 1491650 thrS Haemophilus ducreyi 35000HP threonyl-tRNA synthetase NP_874164.1 1507243 R 233412 CDS NP_874165.1 33152812 1491651 1509444..1510343 1 NC_002940.2 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1510343 ppnK 1491651 ppnK Haemophilus ducreyi 35000HP inorganic polyphosphate/ATP-NAD kinase NP_874165.1 1509444 D 233412 CDS NP_874166.1 33152813 1491652 complement(1510375..1510968) 1 NC_002940.2 MAF protein 1510968 1491652 HD1805 Haemophilus ducreyi 35000HP MAF protein NP_874166.1 1510375 R 233412 CDS NP_874167.1 33152814 1491653 complement(1511041..1512495) 1 NC_002940.2 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 1512495 thiI 1491653 thiI Haemophilus ducreyi 35000HP thiamine biosynthesis protein ThiI NP_874167.1 1511041 R 233412 CDS NP_874168.1 33152815 1491654 complement(1512620..1513918) 1 NC_002940.2 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1513918 purA 1491654 purA Haemophilus ducreyi 35000HP adenylosuccinate synthetase NP_874168.1 1512620 R 233412 CDS NP_874169.1 33152816 1491655 complement(1514054..1514941) 1 NC_002940.2 HflC protein 1514941 hflC 1491655 hflC Haemophilus ducreyi 35000HP HflC protein NP_874169.1 1514054 R 233412 CDS NP_874170.1 33152817 1491656 complement(1514944..1516149) 1 NC_002940.2 HflK protein 1516149 hflK 1491656 hflK Haemophilus ducreyi 35000HP HflK protein NP_874170.1 1514944 R 233412 CDS NP_874171.1 33152818 1491657 complement(1516348..1516665) 1 NC_002940.2 thioredoxin 1516665 trxA 1491657 trxA Haemophilus ducreyi 35000HP thioredoxin NP_874171.1 1516348 R 233412 CDS NP_874172.1 33152819 1491658 complement(1516764..1518056) 1 NC_002940.2 xanthine permease 1518056 1491658 HD1811 Haemophilus ducreyi 35000HP xanthine permease NP_874172.1 1516764 R 233412 CDS NP_874173.1 33152820 1491659 complement(1518134..1519972) 1 NC_002940.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1519972 uvrC 1491659 uvrC Haemophilus ducreyi 35000HP excinuclease ABC subunit C NP_874173.1 1518134 R 233412 CDS NP_874174.1 33152821 1491660 complement(1520059..1520613) 1 NC_002940.2 phosphatidylglycerophosphate synthase; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1520613 pgsA 1491660 pgsA Haemophilus ducreyi 35000HP CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase NP_874174.1 1520059 R 233412 CDS NP_874175.1 33152822 1491661 1520796..1521461 1 NC_002940.2 transporter 1521461 1491661 HD1814 Haemophilus ducreyi 35000HP transporter NP_874175.1 1520796 D 233412 CDS NP_874176.1 33152823 1491662 1521523..1521858 1 NC_002940.2 sulfite reductase 1521858 1491662 HD1815 Haemophilus ducreyi 35000HP sulfite reductase NP_874176.1 1521523 D 233412 CDS NP_874177.1 33152824 1491663 1521929..1522834 1 NC_002940.2 iron ABC transporter substrate-binding proten 1522834 yfeA 1491663 yfeA Haemophilus ducreyi 35000HP iron ABC transporter substrate-binding proten NP_874177.1 1521929 D 233412 CDS NP_874178.1 33152825 1491664 1522831..1523589 1 NC_002940.2 iron (chelated) transporter ATP-binding protein 1523589 yfeB 1491664 yfeB Haemophilus ducreyi 35000HP iron (chelated) transporter ATP-binding protein NP_874178.1 1522831 D 233412 CDS NP_874179.1 33152826 1491665 1523795..1524334 1 NC_002940.2 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1524334 apt 1491665 apt Haemophilus ducreyi 35000HP adenine phosphoribosyltransferase NP_874179.1 1523795 D 233412 CDS NP_874180.1 33152827 1491666 1524362..1526425 1 NC_002940.2 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1526425 dnaX 1491666 dnaX Haemophilus ducreyi 35000HP DNA polymerase III subunits gamma and tau NP_874180.1 1524362 D 233412 CDS NP_874181.1 33152828 1491667 1526425..1527345 1 NC_002940.2 ABC transporter ATP-binding protein 1527345 1491667 HD1820 Haemophilus ducreyi 35000HP ABC transporter ATP-binding protein NP_874181.1 1526425 D 233412 CDS NP_874182.1 33152829 1491668 1527348..1528109 1 NC_002940.2 ABC transporter 1528109 1491668 HD1821 Haemophilus ducreyi 35000HP ABC transporter NP_874182.1 1527348 D 233412 CDS NP_874183.1 33152830 1491669 1528188..1528946 1 NC_002940.2 molybdate-binding periplasmic protein, ABC transporter 1528946 modA 1491669 modA Haemophilus ducreyi 35000HP molybdate-binding periplasmic protein, ABC transporter NP_874183.1 1528188 D 233412 CDS NP_874184.1 33152831 1491670 1529022..1529714 1 NC_002940.2 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 1529714 modB 1491670 modB Haemophilus ducreyi 35000HP molybdate ABC transporter permease NP_874184.1 1529022 D 233412 CDS NP_874185.1 33152832 1491671 1529639..1529740 1 NC_002940.2 hypothetical protein 1529740 1491671 HD1825 Haemophilus ducreyi 35000HP hypothetical protein NP_874185.1 1529639 D 233412 CDS NP_874186.1 33152833 1491672 1529733..1530788 1 NC_002940.2 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 1530788 modC 1491672 modC Haemophilus ducreyi 35000HP molybdate transporter ATP-binding protein NP_874186.1 1529733 D 233412 CDS NP_874187.1 33152834 1491673 1530836..1531270 1 NC_002940.2 hypothetical protein 1531270 1491673 HD1827 Haemophilus ducreyi 35000HP hypothetical protein NP_874187.1 1530836 D 233412 CDS NP_874188.1 33152835 1491674 1531260..1531562 1 NC_002940.2 hypothetical protein 1531562 1491674 HD1828 Haemophilus ducreyi 35000HP hypothetical protein NP_874188.1 1531260 D 233412 CDS NP_874189.1 33152836 1491675 complement(1531604..1533010) 1 NC_002940.2 outer membrane protein 1533010 1491675 HD1829 Haemophilus ducreyi 35000HP outer membrane protein NP_874189.1 1531604 R 233412 CDS NP_874190.1 33152837 1491676 complement(1533123..1533743) 1 NC_002940.2 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1533743 gmk 1491676 gmk Haemophilus ducreyi 35000HP guanylate kinase NP_874190.1 1533123 R 233412 CDS NP_874191.1 33152838 1491677 complement(1533812..1534285) 1 NC_002940.2 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 1534285 gpt 1491677 gpt Haemophilus ducreyi 35000HP xanthine-guanine phosphoribosyltransferase NP_874191.1 1533812 R 233412 CDS NP_874192.1 33152839 1491678 1534457..1535905 1 NC_002940.2 aminoacyl-histidine dipeptidase 1535905 pepD 1491678 pepD Haemophilus ducreyi 35000HP aminoacyl-histidine dipeptidase NP_874192.1 1534457 D 233412 CDS NP_874193.1 33152840 1491687 complement(1541896..1542618) 1 NC_002940.2 UDP-N-acetyl-D-mannosaminuronic acid transferase 1542618 wecG 1491687 wecG Haemophilus ducreyi 35000HP UDP-N-acetyl-D-mannosaminuronic acid transferase NP_874193.1 1541896 R 233412 CDS NP_874194.1 33152841 1491688 complement(1542620..1543924) 1 NC_002940.2 enterobacterial common antigen polymerase; common antigen polymerase 1543924 1491688 HD1835 Haemophilus ducreyi 35000HP common antigen polymerase NP_874194.1 1542620 R 233412 CDS NP_874195.1 33152842 1491689 complement(1543921..1545018) 1 NC_002940.2 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 1545018 wecF 1491689 wecF Haemophilus ducreyi 35000HP 4-alpha-L-fucosyltransferase NP_874195.1 1543921 R 233412 CDS NP_874196.1 33152843 1491691 complement(1546298..1547428) 1 NC_002940.2 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 1547428 wecE 1491691 wecE Haemophilus ducreyi 35000HP TDP-4-oxo-6-deoxy-D-glucose transaminase NP_874196.1 1546298 R 233412 CDS NP_874197.1 33152844 1491692 complement(1547415..1548089) 1 NC_002940.2 TDP-fucosamine acetyltransferase 1548089 wecD 1491692 wecD Haemophilus ducreyi 35000HP TDP-fucosamine acetyltransferase NP_874197.1 1547415 R 233412 CDS NP_874198.1 33152845 1491693 complement(1548092..1549369) 1 NC_002940.2 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 1549369 wecC 1491693 wecC Haemophilus ducreyi 35000HP UDP-N-acetyl-D-mannosamine dehydrogenase NP_874198.1 1548092 R 233412 CDS NP_874199.1 33152846 1491694 complement(1549432..1550511) 1 NC_002940.2 UDP-N-acetylglucosamine 2-epimerase 1550511 wecB 1491694 wecB Haemophilus ducreyi 35000HP UDP-N-acetylglucosamine 2-epimerase NP_874199.1 1549432 R 233412 CDS NP_874200.1 33152847 1491695 complement(1550592..1551749) 1 NC_002940.2 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 1551749 wecA 1491695 wecA Haemophilus ducreyi 35000HP undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase NP_874200.1 1550592 R 233412 CDS NP_874201.1 33152848 1491696 complement(1551850..1552995) 1 NC_002940.2 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 1552995 nagA 1491696 nagA Haemophilus ducreyi 35000HP N-acetylglucosamine-6-phosphate deacetylase NP_874201.1 1551850 R 233412 CDS NP_874202.1 33152849 1491697 complement(1553043..1553846) 1 NC_002940.2 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 1553846 nagB 1491697 nagB Haemophilus ducreyi 35000HP glucosamine-6-phosphate deaminase NP_874202.1 1553043 R 233412 CDS NP_874203.1 33152850 1491698 complement(1554010..1554819) 1 NC_002940.2 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 1554819 nanA 1491698 nanA Haemophilus ducreyi 35000HP N-acetylneuraminate lyase NP_874203.1 1554010 R 233412 CDS NP_874204.1 33152851 1491699 complement(1555079..1555768) 1 NC_002940.2 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1555768 nanE 1491699 nanE Haemophilus ducreyi 35000HP N-acetylmannosamine-6-phosphate 2-epimerase NP_874204.1 1555079 R 233412 CDS NP_874205.1 33152852 1491700 1556101..1557810 1 NC_002940.2 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 1557810 menD 1491700 menD Haemophilus ducreyi 35000HP 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase NP_874205.1 1556101 D 233412 CDS NP_874206.1 33152853 1491701 1557810..1558595 1 NC_002940.2 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase 1558595 1491701 HD1854 Haemophilus ducreyi 35000HP acyl-CoA thioester hydrolase NP_874206.1 1557810 D 233412 CDS NP_874207.1 33152854 1491702 complement(1558660..1559625) 1 NC_002940.2 hypothetical protein 1559625 1491702 HD1856 Haemophilus ducreyi 35000HP hypothetical protein NP_874207.1 1558660 R 233412 CDS NP_874208.1 33152855 1491703 complement(1559836..1560516) 1 NC_002940.2 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 1560516 ulaD 1491703 ulaD Haemophilus ducreyi 35000HP 3-keto-L-gulonate-6-phosphate decarboxylase NP_874208.1 1559836 R 233412 CDS NP_874209.1 33152856 1491704 complement(1560657..1561124) 1 NC_002940.2 PTS system enzyme II-A permease 1561124 1491704 HD1859 Haemophilus ducreyi 35000HP PTS system enzyme II-A permease NP_874209.1 1560657 R 233412 CDS NP_874210.1 33152857 1491705 complement(1561193..1563010) 1 NC_002940.2 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunits IICB 1563010 ulaA 1491705 ulaA Haemophilus ducreyi 35000HP PTS system ascorbate-specific transporter subunits IICB NP_874210.1 1561193 R 233412 CDS NP_874211.1 33152858 1491706 1563470..1564561 1 NC_002940.2 L-ascorbate 6-phosphate lactonase 1564561 1491706 HD1861 Haemophilus ducreyi 35000HP L-ascorbate 6-phosphate lactonase NP_874211.1 1563470 D 233412 CDS NP_874212.1 33152859 1491707 1564660..1565406 1 NC_002940.2 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 1565406 1491707 HD1863 Haemophilus ducreyi 35000HP transcriptional repressor UlaR NP_874212.1 1564660 D 233412 CDS NP_874213.1 33152860 1491708 1565498..1566358 1 NC_002940.2 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 1566358 sgbU 1491708 sgbU Haemophilus ducreyi 35000HP L-xylulose 5-phosphate 3-epimerase NP_874213.1 1565498 D 233412 CDS NP_874214.1 33152861 1491709 1566352..1567065 1 NC_002940.2 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 1567065 araD 1491709 araD Haemophilus ducreyi 35000HP L-ribulose-5-phosphate 4-epimerase NP_874214.1 1566352 D 233412 CDS NP_874215.1 33152862 1491711 complement(1567393..1567491) 1 NC_002940.2 hypothetical protein 1567491 1491711 HD1869 Haemophilus ducreyi 35000HP hypothetical protein NP_874215.1 1567393 R 233412 CDS NP_874216.1 33152863 1491713 1569291..1570496 1 NC_002940.2 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 1570496 ubiF 1491713 ubiF Haemophilus ducreyi 35000HP 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase NP_874216.1 1569291 D 233412 CDS NP_874217.1 33152864 1491714 complement(1570582..1571808) 1 NC_002940.2 tyrosine-specific transport protein; tyrosine permease 1571808 tryP 1491714 tryP Haemophilus ducreyi 35000HP tyrosine permease NP_874217.1 1570582 R 233412 CDS NP_874218.1 33152865 1491715 complement(1572052..1576314) 1 NC_002940.2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1576314 rpoC 1491715 rpoC Haemophilus ducreyi 35000HP DNA-directed RNA polymerase subunit beta' NP_874218.1 1572052 R 233412 CDS NP_874219.1 33152866 1491716 complement(1576480..1580508) 1 NC_002940.2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1580508 rpoB 1491716 rpoB Haemophilus ducreyi 35000HP DNA-directed RNA polymerase subunit beta NP_874219.1 1576480 R 233412 CDS NP_874220.1 33152867 1491717 1580540..1580695 1 NC_002940.2 hypothetical protein 1580695 1491717 HD1878 Haemophilus ducreyi 35000HP hypothetical protein NP_874220.1 1580540 D 233412 CDS NP_874221.1 33152868 1491718 complement(1580958..1581320) 1 NC_002940.2 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1581320 rplL 1491718 rplL Haemophilus ducreyi 35000HP 50S ribosomal protein L7/L12 NP_874221.1 1580958 R 233412 CDS NP_874222.1 33152869 1491719 complement(1581381..1581872) 1 NC_002940.2 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1581872 rplJ 1491719 rplJ Haemophilus ducreyi 35000HP 50S ribosomal protein L10 NP_874222.1 1581381 R 233412 CDS NP_874223.1 33152870 1491720 complement(1582146..1582835) 1 NC_002940.2 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1582835 rplA 1491720 rplA Haemophilus ducreyi 35000HP 50S ribosomal protein L1 NP_874223.1 1582146 R 233412 CDS NP_874224.1 33152871 1491721 complement(1582840..1583268) 1 NC_002940.2 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1583268 rplK 1491721 rplK Haemophilus ducreyi 35000HP 50S ribosomal protein L11 NP_874224.1 1582840 R 233412 CDS NP_874225.1 33152872 1491722 complement(1583456..1584019) 1 NC_002940.2 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1584019 nusG 1491722 nusG Haemophilus ducreyi 35000HP transcription antitermination protein NusG NP_874225.1 1583456 R 233412 CDS NP_874226.1 33152873 1491723 complement(1584021..1584437) 1 NC_002940.2 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1584437 secE 1491723 secE Haemophilus ducreyi 35000HP preprotein translocase subunit SecE NP_874226.1 1584021 R 233412 CDS NP_874227.1 33152874 1491724 1584727..1586736 1 NC_002940.2 oligopeptide transporter 1586736 1491724 HD1887 Haemophilus ducreyi 35000HP oligopeptide transporter NP_874227.1 1584727 D 233412 CDS NP_874228.1 33152875 1491725 complement(1586846..1587988) 1 NC_002940.2 smf protein; DNA processing chain A 1587988 smf 1491725 smf Haemophilus ducreyi 35000HP DNA processing chain A NP_874228.1 1586846 R 233412 CDS NP_874229.1 33152876 1491726 1588178..1588693 1 NC_002940.2 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1588693 def 1491726 def Haemophilus ducreyi 35000HP peptide deformylase NP_874229.1 1588178 D 233412 CDS NP_874230.1 33152877 1491727 1588825..1589766 1 NC_002940.2 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 1589766 rfaD 1491727 rfaD Haemophilus ducreyi 35000HP ADP-L-glycero-D-manno-heptose-6-epimerase NP_874230.1 1588825 D 233412 CDS NP_874231.1 33152878 1491728 complement(1589862..1590194) 1 NC_002940.2 drug resistance protein 1590194 1491728 HD1891 Haemophilus ducreyi 35000HP drug resistance protein NP_874231.1 1589862 R 233412 CDS NP_874232.1 33152879 1491729 complement(1590650..1591066) 1 NC_002940.2 hypothetical protein 1591066 1491729 HD1892 Haemophilus ducreyi 35000HP hypothetical protein NP_874232.1 1590650 R 233412 CDS NP_874233.1 33152880 1491730 complement(1591072..1591368) 1 NC_002940.2 hypothetical protein 1591368 1491730 HD1893 Haemophilus ducreyi 35000HP hypothetical protein NP_874233.1 1591072 R 233412 CDS NP_874234.1 33152881 1491731 complement(1591723..1593555) 1 NC_002940.2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 1593555 glmS 1491731 glmS Haemophilus ducreyi 35000HP glucosamine--fructose-6-phosphate aminotransferase NP_874234.1 1591723 R 233412 CDS NP_874235.1 33152882 1491732 complement(1593664..1595628) 1 NC_002940.2 adhesin processing HmwC-like protein 1595628 1491732 HD1895 Haemophilus ducreyi 35000HP adhesin processing HmwC-like protein NP_874235.1 1593664 R 233412 CDS NP_874236.1 33152883 1491733 complement(1595656..1596987) 1 NC_002940.2 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 1596987 rimO 1491733 rimO Haemophilus ducreyi 35000HP ribosomal protein S12 methylthiotransferase NP_874236.1 1595656 R 233412 CDS NP_874237.1 33152884 1491734 complement(1597024..1597134) 1 NC_002940.2 hypothetical protein 1597134 1491734 HD1897 Haemophilus ducreyi 35000HP hypothetical protein NP_874237.1 1597024 R 233412 CDS NP_874238.1 33152885 1491735 complement(1597170..1597868) 1 NC_002940.2 Includes: 5'-methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase; MTA/SAH nucleosidase 1597868 mtn 1491735 mtn Haemophilus ducreyi 35000HP MTA/SAH nucleosidase NP_874238.1 1597170 R 233412 CDS NP_874239.1 33152886 1491736 complement(1597988..1598209) 1 NC_002940.2 hypothetical protein 1598209 slyX 1491736 slyX Haemophilus ducreyi 35000HP hypothetical protein NP_874239.1 1597988 R 233412 CDS NP_874240.1 33152887 1491737 1598298..1599032 1 NC_002940.2 FKBP-type peptidylprolyl isomerase 1599032 fkpA 1491737 fkpA Haemophilus ducreyi 35000HP FKBP-type peptidylprolyl isomerase NP_874240.1 1598298 D 233412 CDS NP_874241.1 33152888 1491738 1599143..1599805 1 NC_002940.2 hypothetical protein 1599805 1491738 HD1901 Haemophilus ducreyi 35000HP hypothetical protein NP_874241.1 1599143 D 233412 CDS NP_874242.1 33152889 1491739 1599805..1600182 1 NC_002940.2 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 1600182 1491739 HD1902 Haemophilus ducreyi 35000HP sulfur transfer complex subunit TusD NP_874242.1 1599805 D 233412 CDS NP_874243.1 33152890 1491740 1600185..1600556 1 NC_002940.2 hypothetical protein 1600556 1491740 HD1903 Haemophilus ducreyi 35000HP hypothetical protein NP_874243.1 1600185 D 233412 CDS NP_874244.1 33152891 1491741 1600577..1600843 1 NC_002940.2 hypothetical protein 1600843 1491741 HD1904 Haemophilus ducreyi 35000HP hypothetical protein NP_874244.1 1600577 D 233412 CDS NP_874245.1 33152892 1491747 complement(1606459..1607256) 1 NC_002940.2 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1607256 murI 1491747 murI Haemophilus ducreyi 35000HP glutamate racemase NP_874245.1 1606459 R 233412 CDS NP_874246.1 33152893 1491749 complement(1608322..1608765) 1 NC_002940.2 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 1608765 asnC 1491749 asnC Haemophilus ducreyi 35000HP DNA-binding transcriptional regulator AsnC NP_874246.1 1608322 R 233412 CDS NP_874247.1 33152894 1491750 1608766..1608885 1 NC_002940.2 hypothetical protein 1608885 1491750 HD1912 Haemophilus ducreyi 35000HP hypothetical protein NP_874247.1 1608766 D 233412 CDS NP_874248.1 33152895 1491751 1608977..1609969 1 NC_002940.2 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 1609969 asnA 1491751 asnA Haemophilus ducreyi 35000HP asparagine synthetase AsnA NP_874248.1 1608977 D 233412 CDS NP_874249.1 33152896 1491752 complement(1610073..1610666) 1 NC_002940.2 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 1610666 1491752 HD1915 Haemophilus ducreyi 35000HP sulfite oxidase subunit YedZ NP_874249.1 1610073 R 233412 CDS NP_874250.1 33152897 1491753 complement(1610666..1611622) 1 NC_002940.2 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 1611622 1491753 HD1916 Haemophilus ducreyi 35000HP sulfite oxidase subunit YedY NP_874250.1 1610666 R 233412 CDS NP_874251.1 33152898 1491754 1611711..1612295 1 NC_002940.2 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 1612295 1491754 HD1917 Haemophilus ducreyi 35000HP RNA polymerase sigma factor NP_874251.1 1611711 D 233412 CDS NP_874252.1 33152899 1491755 1612295..1612489 1 NC_002940.2 hypothetical protein 1612489 1491755 HD1918 Haemophilus ducreyi 35000HP hypothetical protein NP_874252.1 1612295 D 233412 CDS NP_874253.1 33152900 1491756 complement(1612594..1614309) 1 NC_002940.2 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1614309 proS 1491756 proS Haemophilus ducreyi 35000HP prolyl-tRNA synthetase NP_874253.1 1612594 R 233412 CDS NP_874254.1 33152901 1491757 complement(1614444..1615334) 1 NC_002940.2 hypothetical protein 1615334 1491757 HD1920 Haemophilus ducreyi 35000HP hypothetical protein NP_874254.1 1614444 R 233412 CDS NP_874255.1 33152902 1491758 1615543..1617636 1 NC_002940.2 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1617636 recG 1491758 recG Haemophilus ducreyi 35000HP ATP-dependent DNA helicase RecG NP_874255.1 1615543 D 233412 CDS NP_874256.1 33152903 1491759 1617755..1618060 1 NC_002940.2 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1618060 rpoZ 1491759 rpoZ Haemophilus ducreyi 35000HP DNA-directed RNA polymerase subunit omega NP_874256.1 1617755 D 233412 CDS NP_874257.1 33152904 1491760 1618164..1619870 1 NC_002940.2 ppGpp pyrophosphohydrolase; guanosine-3',5'-bis(diphosphate) 3'- pyrophosphohydrolase 1619870 spoT 1491760 spoT Haemophilus ducreyi 35000HP guanosine-3',5'-bis(diphosphate) 3'- pyrophosphohydrolase NP_874257.1 1618164 D 233412 CDS NP_874258.1 33152905 1491761 1619989..1620846 1 NC_002940.2 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 1620846 menB 1491761 menB Haemophilus ducreyi 35000HP naphthoate synthase NP_874258.1 1619989 D 233412 CDS NP_874259.1 33152906 1491762 complement(1621015..1621140) 1 NC_002940.2 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 1621140 rpmJ 1491762 rpmJ Haemophilus ducreyi 35000HP 50S ribosomal protein L36 NP_874259.1 1621015 R 233412 CDS NP_874260.1 33152907 1491763 complement(1621152..1621421) 1 NC_002940.2 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1621421 rpmE2 1491763 rpmE2 Haemophilus ducreyi 35000HP 50S ribosomal protein L31 NP_874260.1 1621152 R 233412 CDS NP_874261.1 33152908 1491764 1621675..1622349 1 NC_002940.2 pentose-5-phosphate 3- epimerase; D-ribulose-phosphate-3 epimerase 1622349 rpe 1491764 rpe Haemophilus ducreyi 35000HP D-ribulose-phosphate-3 epimerase NP_874261.1 1621675 D 233412 CDS NP_874262.1 33152909 1491765 complement(1622508..1622600) 1 NC_002940.2 hypothetical protein 1622600 1491765 HD1930 Haemophilus ducreyi 35000HP hypothetical protein NP_874262.1 1622508 R 233412 CDS NP_874263.1 33152910 1491766 1622630..1622863 1 NC_002940.2 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1622863 acpP 1491766 acpP Haemophilus ducreyi 35000HP acyl carrier protein NP_874263.1 1622630 D 233412 CDS NP_874264.1 33152911 1491768 1623259..1624293 1 NC_002940.2 hypothetical protein 1624293 1491768 HD1932 Haemophilus ducreyi 35000HP hypothetical protein NP_874264.1 1623259 D 233412 CDS NP_874265.1 33152912 1491769 1624280..1624924 1 NC_002940.2 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1624924 tmk 1491769 tmk Haemophilus ducreyi 35000HP thymidylate kinase NP_874265.1 1624280 D 233412 CDS NP_874266.1 33152913 1491770 1624937..1625923 1 NC_002940.2 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1625923 holB 1491770 holB Haemophilus ducreyi 35000HP DNA polymerase III subunit delta' NP_874266.1 1624937 D 233412 CDS NP_874267.1 33152914 1491771 1625962..1626750 1 NC_002940.2 deoxyribonuclease 1626750 1491771 HD1936 Haemophilus ducreyi 35000HP deoxyribonuclease NP_874267.1 1625962 D 233412 CDS NP_874268.1 33152915 1491772 1626806..1627345 1 NC_002940.2 hypothetical protein 1627345 1491772 HD1937 Haemophilus ducreyi 35000HP hypothetical protein NP_874268.1 1626806 D 233412 CDS NP_874269.1 33152916 1491773 1627415..1628119 1 NC_002940.2 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 1628119 lpxH 1491773 lpxH Haemophilus ducreyi 35000HP UDP-2,3-diacylglucosamine hydrolase NP_874269.1 1627415 D 233412 CDS NP_874270.1 33152917 1491774 1628278..1628670 1 NC_002940.2 hypothetical protein 1628670 1491774 HD1939 Haemophilus ducreyi 35000HP hypothetical protein NP_874270.1 1628278 D 233412 CDS NP_874271.1 33152918 1491775 complement(1628667..1629581) 1 NC_002940.2 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1629581 xerC 1491775 xerC Haemophilus ducreyi 35000HP site-specific tyrosine recombinase XerC NP_874271.1 1628667 R 233412 CDS NP_874272.1 33152919 1491776 complement(1629599..1629904) 1 NC_002940.2 hypothetical protein 1629904 1491776 HD1941 Haemophilus ducreyi 35000HP hypothetical protein NP_874272.1 1629599 R 233412 CDS NP_874273.1 33152920 1491777 complement(1629987..1632053) 1 NC_002940.2 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1632053 glyS 1491777 glyS Haemophilus ducreyi 35000HP glycyl-tRNA synthetase subunit beta NP_874273.1 1629987 R 233412 CDS NP_874274.1 33152921 1491778 complement(1632093..1633001) 1 NC_002940.2 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1633001 glyQ 1491778 glyQ Haemophilus ducreyi 35000HP glycyl-tRNA synthetase subunit alpha NP_874274.1 1632093 R 233412 CDS NP_874275.1 33152922 1491779 1633070..1633162 1 NC_002940.2 hypothetical protein 1633162 1491779 HD1944 Haemophilus ducreyi 35000HP hypothetical protein NP_874275.1 1633070 D 233412 CDS NP_874276.1 33152923 1491780 1633184..1634392 1 NC_002940.2 hypothetical protein 1634392 1491780 HD1945 Haemophilus ducreyi 35000HP hypothetical protein NP_874276.1 1633184 D 233412 CDS NP_874277.1 33152924 1491781 complement(1634484..1634834) 1 NC_002940.2 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1634834 rplS 1491781 rplS Haemophilus ducreyi 35000HP 50S ribosomal protein L19 NP_874277.1 1634484 R 233412 CDS NP_874278.1 33152925 1491782 complement(1634859..1635614) 1 NC_002940.2 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1635614 trmD 1491782 trmD Haemophilus ducreyi 35000HP tRNA (guanine-N(1)-)-methyltransferase NP_874278.1 1634859 R 233412 CDS NP_874279.1 33152926 1491783 complement(1635672..1636199) 1 NC_002940.2 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1636199 rimM 1491783 rimM Haemophilus ducreyi 35000HP 16S rRNA-processing protein RimM NP_874279.1 1635672 R 233412 CDS NP_874280.1 33152927 1491784 complement(1636232..1636480) 1 NC_002940.2 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1636480 rpsP 1491784 rpsP Haemophilus ducreyi 35000HP 30S ribosomal protein S16 NP_874280.1 1636232 R 233412 CDS NP_874281.1 33152928 1491785 complement(1636724..1637107) 1 NC_002940.2 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1637107 rplQ 1491785 rplQ Haemophilus ducreyi 35000HP 50S ribosomal protein L17 NP_874281.1 1636724 R 233412 CDS NP_874282.1 33152929 1491786 complement(1637144..1638133) 1 NC_002940.2 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1638133 rpoA 1491786 rpoA Haemophilus ducreyi 35000HP DNA-directed RNA polymerase subunit alpha NP_874282.1 1637144 R 233412 CDS NP_874283.1 33152930 1491787 complement(1638199..1638825) 1 NC_002940.2 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1638825 rpsD 1491787 rpsD Haemophilus ducreyi 35000HP 30S ribosomal protein S4 NP_874283.1 1638199 R 233412 CDS NP_874284.1 33152931 1491788 complement(1638854..1639243) 1 NC_002940.2 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1639243 rpsK 1491788 rpsK Haemophilus ducreyi 35000HP 30S ribosomal protein S11 NP_874284.1 1638854 R 233412 CDS NP_874285.1 33152932 1491789 complement(1639260..1639616) 1 NC_002940.2 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1639616 rpsM 1491789 rpsM Haemophilus ducreyi 35000HP 30S ribosomal protein S13 NP_874285.1 1639260 R 233412 CDS NP_874286.1 33152933 1491790 complement(1639753..1639866) 1 NC_002940.2 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 1639866 rpmJ 1491790 rpmJ Haemophilus ducreyi 35000HP 50S ribosomal protein L36 NP_874286.1 1639753 R 233412 CDS NP_874287.1 33152934 1491791 complement(1639898..1641217) 1 NC_002940.2 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1641217 secY 1491791 secY Haemophilus ducreyi 35000HP preprotein translocase subunit SecY NP_874287.1 1639898 R 233412 CDS NP_874288.1 33152935 1491792 complement(1641219..1641653) 1 NC_002940.2 late assembly protein; 50S ribosomal protein L15 1641653 rplO 1491792 rplO Haemophilus ducreyi 35000HP 50S ribosomal protein L15 NP_874288.1 1641219 R 233412 CDS NP_874289.1 33152936 1491793 complement(1641658..1641837) 1 NC_002940.2 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 1641837 rpmD 1491793 rpmD Haemophilus ducreyi 35000HP 50S ribosomal protein L30 NP_874289.1 1641658 R 233412 CDS NP_874290.1 33152937 1491794 complement(1641844..1642344) 1 NC_002940.2 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1642344 rpsE 1491794 rpsE Haemophilus ducreyi 35000HP 30S ribosomal protein S5 NP_874290.1 1641844 R 233412 CDS NP_874291.1 33152938 1491795 complement(1642359..1642712) 1 NC_002940.2 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1642712 rplR 1491795 rplR Haemophilus ducreyi 35000HP 50S ribosomal protein L18 NP_874291.1 1642359 R 233412 CDS NP_874292.1 33152939 1491796 complement(1642727..1643260) 1 NC_002940.2 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1643260 rplF 1491796 rplF Haemophilus ducreyi 35000HP 50S ribosomal protein L6 NP_874292.1 1642727 R 233412 CDS NP_874293.1 33152940 1491797 complement(1643276..1643668) 1 NC_002940.2 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1643668 rpsH 1491797 rpsH Haemophilus ducreyi 35000HP 30S ribosomal protein S8 NP_874293.1 1643276 R 233412 CDS NP_874294.1 33152941 1491798 complement(1643700..1644005) 1 NC_002940.2 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1644005 rpsN 1491798 rpsN Haemophilus ducreyi 35000HP 30S ribosomal protein S14 NP_874294.1 1643700 R 233412 CDS NP_874295.1 33152942 1491799 complement(1644017..1644556) 1 NC_002940.2 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1644556 rplE 1491799 rplE Haemophilus ducreyi 35000HP 50S ribosomal protein L5 NP_874295.1 1644017 R 233412 CDS NP_874296.1 33152943 1491800 complement(1644574..1644885) 1 NC_002940.2 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1644885 rplX 1491800 rplX Haemophilus ducreyi 35000HP 50S ribosomal protein L24 NP_874296.1 1644574 R 233412 CDS NP_874297.1 33152944 1491801 complement(1644896..1645267) 1 NC_002940.2 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1645267 rplN 1491801 rplN Haemophilus ducreyi 35000HP 50S ribosomal protein L14 NP_874297.1 1644896 R 233412 CDS NP_874298.1 33152945 1491802 complement(1645368..1645871) 1 NC_002940.2 insertion element IS1 1/5/6 protein InsB 1645871 InsB 1491802 InsB Haemophilus ducreyi 35000HP insertion element IS1 1/5/6 protein InsB NP_874298.1 1645368 R 233412 CDS NP_874299.1 33152946 1491803 complement(1645790..1646065) 1 NC_002940.2 insertion element IS1 1/2/3/5/6 protein InsA 1646065 InsA 1491803 InsA Haemophilus ducreyi 35000HP insertion element IS1 1/2/3/5/6 protein InsA NP_874299.1 1645790 R 233412 CDS NP_874300.1 33152947 1491804 1645995..1646105 1 NC_002940.2 hypothetical protein 1646105 1491804 HD1972 Haemophilus ducreyi 35000HP hypothetical protein NP_874300.1 1645995 D 233412 CDS NP_874301.1 33152948 1491805 1646107..1646211 1 NC_002940.2 hypothetical protein 1646211 1491805 HD1973 Haemophilus ducreyi 35000HP hypothetical protein NP_874301.1 1646107 D 233412 CDS NP_874302.1 33152949 1491806 complement(1646282..1646536) 1 NC_002940.2 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1646536 rpsQ 1491806 rpsQ Haemophilus ducreyi 35000HP 30S ribosomal protein S17 NP_874302.1 1646282 R 233412 CDS NP_874303.1 33152950 1491807 complement(1646536..1646727) 1 NC_002940.2 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 1646727 rpmC 1491807 rpmC Haemophilus ducreyi 35000HP 50S ribosomal protein L29 NP_874303.1 1646536 R 233412 CDS NP_874304.1 33152951 1491808 complement(1646727..1647137) 1 NC_002940.2 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1647137 rplP 1491808 rplP Haemophilus ducreyi 35000HP 50S ribosomal protein L16 NP_874304.1 1646727 R 233412 CDS NP_874305.1 33152952 1491809 complement(1647151..1647855) 1 NC_002940.2 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1647855 rpsC 1491809 rpsC Haemophilus ducreyi 35000HP 30S ribosomal protein S3 NP_874305.1 1647151 R 233412 CDS NP_874306.1 33152953 1491810 complement(1647873..1648205) 1 NC_002940.2 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1648205 rplV 1491810 rplV Haemophilus ducreyi 35000HP 50S ribosomal protein L22 NP_874306.1 1647873 R 233412 CDS NP_874307.1 33152954 1491811 complement(1648218..1648493) 1 NC_002940.2 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1648493 rpsS 1491811 rpsS Haemophilus ducreyi 35000HP 30S ribosomal protein S19 NP_874307.1 1648218 R 233412 CDS NP_874308.1 33152955 1491812 complement(1648523..1649344) 1 NC_002940.2 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1649344 rplB 1491812 rplB Haemophilus ducreyi 35000HP 50S ribosomal protein L2 NP_874308.1 1648523 R 233412 CDS NP_874309.1 33152956 1491813 complement(1649365..1649670) 1 NC_002940.2 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1649670 rplW 1491813 rplW Haemophilus ducreyi 35000HP 50S ribosomal protein L23 NP_874309.1 1649365 R 233412 CDS NP_874310.1 33152957 1491814 complement(1649667..1650269) 1 NC_002940.2 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1650269 rplD 1491814 rplD Haemophilus ducreyi 35000HP 50S ribosomal protein L4 NP_874310.1 1649667 R 233412 CDS NP_874311.1 33152958 1491815 complement(1650285..1650911) 1 NC_002940.2 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1650911 rplC 1491815 rplC Haemophilus ducreyi 35000HP 50S ribosomal protein L3 NP_874311.1 1650285 R 233412 CDS NP_874312.1 33152959 1491816 complement(1650937..1651248) 1 NC_002940.2 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 1651248 rpsJ 1491816 rpsJ Haemophilus ducreyi 35000HP 30S ribosomal protein S10 NP_874312.1 1650937 R 233412 CDS NP_874313.1 33152960 1491817 1651665..1652300 1 NC_002940.2 DNA transformation protein 1652300 1491817 HD1985 Haemophilus ducreyi 35000HP DNA transformation protein NP_874313.1 1651665 D 233412 CDS NP_874314.1 33152961 1491818 1652441..1653835 1 NC_002940.2 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1653835 fumC 1491818 fumC Haemophilus ducreyi 35000HP fumarate hydratase NP_874314.1 1652441 D 233412 CDS NP_874315.1 33152962 1491819 complement(1653949..1655475) 1 NC_002940.2 MviN virulence factor 1655475 mviN 1491819 mviN Haemophilus ducreyi 35000HP MviN virulence factor NP_874315.1 1653949 R 233412 CDS NP_874316.1 33152963 1491820 complement(1655510..1655629) 1 NC_002940.2 hypothetical protein 1655629 1491820 HD1989 Haemophilus ducreyi 35000HP hypothetical protein NP_874316.1 1655510 R 233412 CDS NP_874317.2 161511520 1491821 1655878..1656141 1 NC_002940.2 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1656141 rpsT 1491821 rpsT Haemophilus ducreyi 35000HP 30S ribosomal protein S20 NP_874317.2 1655878 D 233412 CDS NP_874318.1 33152965 1491822 complement(1656198..1657574) 1 NC_002940.2 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 1657574 trkA 1491822 trkA Haemophilus ducreyi 35000HP potassium transporter peripheral membrane protein NP_874318.1 1656198 R 233412 CDS NP_874319.1 33152966 1491823 complement(1657574..1658881) 1 NC_002940.2 Fmu protein 1658881 sun 1491823 sun Haemophilus ducreyi 35000HP Fmu protein NP_874319.1 1657574 R 233412 CDS NP_874320.1 33152967 1491824 complement(1658931..1660799) 1 NC_002940.2 selenocysteine-specific elongation factor; SelB translation factor 1660799 selB 1491824 selB Haemophilus ducreyi 35000HP SelB translation factor NP_874320.1 1658931 R 233412 CDS NP_874321.1 33152968 1491825 complement(1660796..1662178) 1 NC_002940.2 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 1662178 selA 1491825 selA Haemophilus ducreyi 35000HP selenocysteine synthase NP_874321.1 1660796 R 233412 CDS NP_874322.1 33152969 1491826 1662317..1662427 1 NC_002940.2 hypothetical protein 1662427 1491826 HD1995 Haemophilus ducreyi 35000HP hypothetical protein NP_874322.1 1662317 D 233412 CDS NP_874323.1 33152970 1491827 1662462..1662917 1 NC_002940.2 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 1662917 mioC 1491827 mioC Haemophilus ducreyi 35000HP flavodoxin NP_874323.1 1662462 D 233412 CDS NP_874324.1 33152971 1491828 complement(1662879..1662971) 1 NC_002940.2 hypothetical protein 1662971 1491828 HD1997 Haemophilus ducreyi 35000HP hypothetical protein NP_874324.1 1662879 R 233412 CDS NP_874325.1 33152972 1491829 complement(1662997..1664349) 1 NC_002940.2 signal recognition particle protein 1664349 ffh 1491829 ffh Haemophilus ducreyi 35000HP signal recognition particle protein NP_874325.1 1662997 R 233412 CDS NP_874326.1 33152973 1491833 complement(1666187..1667290) 1 NC_002940.2 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 1667290 mltC 1491833 mltC Haemophilus ducreyi 35000HP murein transglycosylase C NP_874326.1 1666187 R 233412 CDS NP_874327.1 33152974 1491834 complement(1667294..1667578) 1 NC_002940.2 hypothetical protein 1667578 1491834 HD2003 Haemophilus ducreyi 35000HP hypothetical protein NP_874327.1 1667294 R 233412 CDS NP_874328.1 33152975 1491835 complement(1667582..1668670) 1 NC_002940.2 A/G-specific adenine glycosylase 1668670 mutY 1491835 mutY Haemophilus ducreyi 35000HP A/G-specific adenine glycosylase NP_874328.1 1667582 R 233412 CDS NP_874329.1 33152976 1491836 1668916..1669437 1 NC_002940.2 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 1669437 hslV 1491836 hslV Haemophilus ducreyi 35000HP ATP-dependent protease peptidase subunit NP_874329.1 1668916 D 233412 CDS NP_874330.1 33152977 1491837 1669500..1670846 1 NC_002940.2 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding protein HslU 1670846 hslU 1491837 hslU Haemophilus ducreyi 35000HP ATP-dependent protease ATP-binding protein HslU NP_874330.1 1669500 D 233412 CDS NP_874331.1 33152978 1491839 complement(1675033..1675461) 1 NC_002940.2 hypothetical protein 1675461 1491839 HD2011 Haemophilus ducreyi 35000HP hypothetical protein NP_874331.1 1675033 R 233412 CDS NP_874332.1 33152979 1491840 complement(1675581..1676573) 1 NC_002940.2 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1676573 lipA 1491840 lipA Haemophilus ducreyi 35000HP lipoyl synthase NP_874332.1 1675581 R 233412 CDS NP_874333.1 33152980 1491841 complement(1676667..1677341) 1 NC_002940.2 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 1677341 lipB 1491841 lipB Haemophilus ducreyi 35000HP lipoate-protein ligase B NP_874333.1 1676667 R 233412 CDS NP_874334.1 33152981 1491842 complement(1677364..1677507) 1 NC_002940.2 hypothetical protein 1677507 1491842 HD2014 Haemophilus ducreyi 35000HP hypothetical protein NP_874334.1 1677364 R 233412 CDS NP_874335.1 33152982 1491843 complement(1677549..1677842) 1 NC_002940.2 hypothetical protein 1677842 1491843 HD2015 Haemophilus ducreyi 35000HP hypothetical protein NP_874335.1 1677549 R 233412 CDS NP_874336.1 33152983 1491844 complement(1677958..1679139) 1 NC_002940.2 penicillin-binding protein 5; D-alanyl-D-alanine carboxypeptidase fraction A 1679139 dacA 1491844 dacA Haemophilus ducreyi 35000HP D-alanyl-D-alanine carboxypeptidase fraction A NP_874336.1 1677958 R 233412 CDS NP_874337.1 33152984 1491845 complement(1679238..1679792) 1 NC_002940.2 rare lipoprotein A 1679792 1491845 HD2017 Haemophilus ducreyi 35000HP rare lipoprotein A NP_874337.1 1679238 R 233412 CDS NP_874338.1 33152985 1491846 complement(1679925..1681049) 1 NC_002940.2 rod-shape-determining protein RodA 1681049 mrdB 1491846 mrdB Haemophilus ducreyi 35000HP rod-shape-determining protein RodA NP_874338.1 1679925 R 233412 CDS NP_874339.1 33152986 1491847 complement(1681042..1683003) 1 NC_002940.2 penicillin binding protein 2 1683003 mrdA 1491847 mrdA Haemophilus ducreyi 35000HP penicillin binding protein 2 NP_874339.1 1681042 R 233412 CDS NP_874340.1 33152987 1491848 complement(1683020..1683487) 1 NC_002940.2 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 1683487 1491848 HD2022 Haemophilus ducreyi 35000HP rRNA large subunit methyltransferase NP_874340.1 1683020 R 233412 CDS NP_874341.1 33152988 1491849 complement(1683528..1683842) 1 NC_002940.2 hypothetical protein 1683842 1491849 HD2023 Haemophilus ducreyi 35000HP hypothetical protein NP_874341.1 1683528 R 233412 CDS NP_874342.1 33152989 1491850 complement(1683966..1686566) 1 NC_002940.2 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1686566 mutS 1491850 mutS Haemophilus ducreyi 35000HP DNA mismatch repair protein MutS NP_874342.1 1683966 R 233412 CDS NP_874343.1 33152990 1491851 complement(1686700..1689618) 1 NC_002940.2 hemoglobin-binding protein HgbA 1689618 hgbA 1491851 hgbA Haemophilus ducreyi 35000HP hemoglobin-binding protein HgbA NP_874343.1 1686700 R 233412 CDS NP_874344.1 33152991 1491852 complement(1689869..1690270) 1 NC_002940.2 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 1690270 mscL 1491852 mscL Haemophilus ducreyi 35000HP large-conductance mechanosensitive channel NP_874344.1 1689869 R 233412 CDS NP_874345.1 33152992 1491853 complement(1690379..1691839) 1 NC_002940.2 TRK system potassium uptake protein TrkH 1691839 trkH 1491853 trkH Haemophilus ducreyi 35000HP TRK system potassium uptake protein TrkH NP_874345.1 1690379 R 233412 CDS NP_874346.1 33152993 1491854 1691995..1692945 1 NC_002940.2 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1692945 fmt 1491854 fmt Haemophilus ducreyi 35000HP methionyl-tRNA formyltransferase NP_874346.1 1691995 D 233412 CDS NP_874347.1 33152994 1491855 complement(1692997..1695114) 1 NC_002940.2 hypothetical protein 1695114 1491855 HD2030 Haemophilus ducreyi 35000HP hypothetical protein NP_874347.1 1692997 R 233412 CDS NP_874348.1 33152995 1491856 complement(1695251..1696009) 1 NC_002940.2 amino acid ABC transporter ATP-binding protein 1696009 1491856 HD2032 Haemophilus ducreyi 35000HP amino acid ABC transporter ATP-binding protein NP_874348.1 1695251 R 233412 CDS NP_874349.1 33152996 1491857 complement(1696043..1696759) 1 NC_002940.2 amino-acid ABC transporter permease protein 1696759 1491857 HD2033 Haemophilus ducreyi 35000HP amino-acid ABC transporter permease protein NP_874349.1 1696043 R 233412 CDS NP_874350.1 33152997 1491858 complement(1696821..1696922) 1 NC_002940.2 hypothetical protein 1696922 1491858 HD2034 Haemophilus ducreyi 35000HP hypothetical protein NP_874350.1 1696821 R 233412 CDS NP_874351.1 33152998 1491859 complement(1696897..1697679) 1 NC_002940.2 amino acid ABC transporter substrate-binding protein 1697679 1491859 HD2035 Haemophilus ducreyi 35000HP amino acid ABC transporter substrate-binding protein NP_874351.1 1696897 R 233412 CDS NP_874352.1 33152999 1491860 1698210..1698707 1 NC_002940.2 hypothetical protein 1698707 1491860 HD2037 Haemophilus ducreyi 35000HP hypothetical protein NP_874352.1 1698210 D 233412 CDS