-- dump date 20140619_104155 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_247664.1 68248552 3429406 2..1021 1 NC_007146.2 GAPDH; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 1021 gapA 3429406 gapA Haemophilus influenzae 86-028NP glyceraldehyde-3-phosphate dehydrogenase YP_247664.1 2 D 281310 CDS YP_247665.1 68248553 3429407 1191..3014 1 NC_007146.2 Long-chain acyl-CoA synthetase; LACS; Similar to: HI0002, LCFH_HAEIN; long chain fatty acid CoA ligase 3014 3429407 NTHI0002 Haemophilus influenzae 86-028NP long chain fatty acid CoA ligase YP_247665.1 1191 D 281310 CDS YP_247666.1 68248554 3429408 complement(3051..3839) 1 NC_007146.2 Similar to: HI0003, Y003_HAEIN; hypothetical protein 3839 3429408 NTHI0003 Haemophilus influenzae 86-028NP hypothetical protein YP_247666.1 3051 R 281310 CDS YP_247667.1 68248555 3429409 complement(3855..4319) 1 NC_007146.2 Similar to: HI0004, Y004_HAEIN; metalloprotease 4319 3429409 NTHI0004 Haemophilus influenzae 86-028NP metalloprotease YP_247667.1 3855 R 281310 CDS YP_247668.1 68248556 3429410 complement(4581..5393) 1 NC_007146.2 protein required for formate dehydrogenase activity; involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 5393 fdhD 3429410 fdhD Haemophilus influenzae 86-028NP formate dehydrogenase accessory protein YP_247668.1 4581 R 281310 CDS YP_247669.1 68248557 3429411 5664..8750 1 NC_007146.2 formate dehydrogenase alpha subunit; FDH alpha subunit; Similar to: FDXG_HAEIN; Opal (TGA) stop encodes selenocysteine; formate dehydrogenase major subunit 8750 fdxG 3429411 fdxG Haemophilus influenzae 86-028NP formate dehydrogenase major subunit YP_247669.1 5664 D 281310 CDS YP_247670.1 68248558 3429412 8752..9690 1 NC_007146.2 formate dehydrogenase beta subunit; FDH beta subunit; Similar to: HI0007, FDXH_HAEIN; formate dehydrogenase, iron-sulfur subunit 9690 fdxH 3429412 fdxH Haemophilus influenzae 86-028NP formate dehydrogenase, iron-sulfur subunit YP_247670.1 8752 D 281310 CDS YP_247671.1 68248559 3429413 9683..10399 1 NC_007146.2 formate dehydrogenase gamma subunit; FDH gamma subunit; Similar to: HI0008, FDXI_HAEIN; formate dehydrogenase, cytochrome B556 subunit 10399 fdxI 3429413 fdxI Haemophilus influenzae 86-028NP formate dehydrogenase, cytochrome B556 subunit YP_247671.1 9683 D 281310 CDS YP_247672.1 68248560 3429414 10469..11377 1 NC_007146.2 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 11377 fdhE 3429414 fdhE Haemophilus influenzae 86-028NP formate dehydrogenase accessory protein FdhE YP_247672.1 10469 D 281310 CDS YP_247673.1 68248561 3429415 complement(11421..11861) 1 NC_007146.2 acetylating enzyme for N-terminal of ribosomal protein S18; alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 11861 rimI 3429415 rimI Haemophilus influenzae 86-028NP ribosomal-protein-alanine N-acetyltransferase YP_247673.1 11421 R 281310 CDS YP_247674.1 68248562 3429416 complement(11864..12268) 1 NC_007146.2 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 12268 holD 3429416 holD Haemophilus influenzae 86-028NP DNA polymerase III subunit psi YP_247674.1 11864 R 281310 CDS YP_247675.1 68248563 3429417 12374..13366 1 NC_007146.2 rRNA (guanine-N(2)-)-methyltransferase; 16S rRNA m2G1207 methyltransferase; 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 13366 rsmC 3429417 rsmC Haemophilus influenzae 86-028NP 16S ribosomal RNA m2G1207 methyltransferase YP_247675.1 12374 D 281310 CDS YP_247676.1 68248564 3429418 complement(13434..14342) 1 NC_007146.2 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 14342 era 3429418 era Haemophilus influenzae 86-028NP GTP-binding protein Era YP_247676.1 13434 R 281310 CDS YP_247677.1 68248565 3429419 complement(14339..15022) 1 NC_007146.2 RNase III; cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 15022 rnc 3429419 rnc Haemophilus influenzae 86-028NP ribonuclease III YP_247677.1 14339 R 281310 CDS YP_247678.1 68248566 3429420 complement(15024..16073) 1 NC_007146.2 SPase I; Leader peptidase I; Similar to: HI0015, LEP_HAEIN; Signal peptidase I 16073 lepB 3429420 lepB Haemophilus influenzae 86-028NP Signal peptidase I YP_247678.1 15024 R 281310 CDS YP_247679.1 68248567 3429421 complement(16082..17878) 1 NC_007146.2 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 17878 lepA 3429421 lepA Haemophilus influenzae 86-028NP GTP-binding protein LepA YP_247679.1 16082 R 281310 CDS YP_247680.1 68248568 3429422 complement(18047..18430) 1 NC_007146.2 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 18430 3429422 NTHI0022 Haemophilus influenzae 86-028NP autonomous glycyl radical cofactor GrcA YP_247680.1 18047 R 281310 CDS YP_247681.1 68248569 3429423 18688..19347 1 NC_007146.2 UDG; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 19347 ung 3429423 ung Haemophilus influenzae 86-028NP uracil-DNA glycosylase YP_247681.1 18688 D 281310 CDS YP_247682.1 68248570 3429424 complement(19417..20841) 1 NC_007146.2 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 20841 3429424 NTHI0026 Haemophilus influenzae 86-028NP (dimethylallyl)adenosine tRNA methylthiotransferase YP_247682.1 19417 R 281310 CDS YP_247683.1 68248571 3429425 complement(21224..22663) 1 NC_007146.2 Similar to: HI0020, YBHI_HAEIN; hypothetical protein 22663 3429425 NTHI0027 Haemophilus influenzae 86-028NP hypothetical protein YP_247683.1 21224 R 281310 CDS YP_247684.1 68248572 3429426 complement(22665..24062) 1 NC_007146.2 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase; Holo-citrate lyase synthase; Apo-ACP nucleodityltransferase; Similar to: HI0021, CIXG_HAEIN; CitXG 24062 citG 3429426 citG Haemophilus influenzae 86-028NP CitXG YP_247684.1 22665 R 281310 CDS YP_247685.1 68248573 3429427 complement(24243..25745) 1 NC_007146.2 citrase; citrate CoA-transferase subunit; Similar to: HI0022, CILA_HAEIN; citrate lyase alpha chain 25745 citF 3429427 citF Haemophilus influenzae 86-028NP citrate lyase alpha chain YP_247685.1 24243 R 281310 CDS YP_247686.1 68248574 3429428 complement(25760..26635) 1 NC_007146.2 citrase; Citryl-CoA lyase subunit; Similar to: HI0023, CILB_HAEIN; citrate lyase beta chain 26635 citE 3429428 citE Haemophilus influenzae 86-028NP citrate lyase beta chain YP_247686.1 25760 R 281310 CDS YP_247687.1 68248575 3429429 complement(26632..26919) 1 NC_007146.2 citrate lyase gamma chain; acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 26919 citD 3429429 citD Haemophilus influenzae 86-028NP citrate lyase subunit gamma YP_247687.1 26632 R 281310 CDS YP_247688.1 68248576 3431068 complement(26957..27964) 1 NC_007146.2 citrate lyase synthetase; acetate:SH-citrate lyase ligase; Similar to: HI0025, CITC_HAEIN; [citrate (pro-3S)-lyase] ligase 27964 citC 3431068 citC Haemophilus influenzae 86-028NP [citrate (pro-3S)-lyase] ligase YP_247688.1 26957 R 281310 CDS YP_247689.1 68248577 3431069 complement(28215..29177) 1 NC_007146.2 Lip-syn; lipoate synthase; catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 29177 lipA 3431069 lipA Haemophilus influenzae 86-028NP lipoyl synthase YP_247689.1 28215 R 281310 CDS YP_247690.1 68248578 3431070 complement(29231..29869) 1 NC_007146.2 lipoate biosynthesis protein B; lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 29869 lipB 3431070 lipB Haemophilus influenzae 86-028NP lipoate-protein ligase B YP_247690.1 29231 R 281310 CDS YP_247691.1 68248579 3431071 complement(29871..30149) 1 NC_007146.2 Similar to: HI0028, Y028_HAEIN; hypothetical protein 30149 3431071 NTHI0035 Haemophilus influenzae 86-028NP hypothetical protein YP_247691.1 29871 R 281310 CDS YP_247692.1 68248580 3431072 complement(30205..31386) 1 NC_007146.2 D-alanyl-D-alanine carboxypeptidase fraction A; DD-peptidase; DD-carboxypeptidase; PBP-5; Similar to: HI0029, DACA_HAEIN; penicillin-binding protein 5 31386 dacA 3431072 dacA Haemophilus influenzae 86-028NP penicillin-binding protein 5 YP_247692.1 30205 R 281310 CDS YP_247693.1 68248581 3431073 complement(31402..32265) 1 NC_007146.2 Similar to: HI0030, RLPA_HAEIN; RlpA-like protein 32265 rlpA 3431073 rlpA Haemophilus influenzae 86-028NP RlpA-like protein YP_247693.1 31402 R 281310 CDS YP_247694.1 68248582 3431074 complement(32318..33433) 1 NC_007146.2 Similar to: HI0031, RODA_HAEIN; rod shape-determining protein 33433 mrdB 3431074 mrdB Haemophilus influenzae 86-028NP rod shape-determining protein YP_247694.1 32318 R 281310 CDS YP_247695.1 68248583 3431075 complement(33423..35378) 1 NC_007146.2 PBP-2; Similar to: HI0032, PBP2_HAEIN; penicillin-binding protein 2 35378 mrdA 3431075 mrdA Haemophilus influenzae 86-028NP penicillin-binding protein 2 YP_247695.1 33423 R 281310 CDS YP_247696.1 68248584 3431076 complement(35400..35867) 1 NC_007146.2 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 35867 3431076 NTHI0041 Haemophilus influenzae 86-028NP rRNA large subunit methyltransferase YP_247696.1 35400 R 281310 CDS YP_247697.1 68248585 3431077 complement(35921..36229) 1 NC_007146.2 Similar to: HI0034, YBEB_HAEIN; hypothetical protein 36229 3431077 NTHI0042 Haemophilus influenzae 86-028NP hypothetical protein YP_247697.1 35921 R 281310 CDS YP_247698.1 68248586 3431078 complement(36354..38009) 1 NC_007146.2 Similar to: HI0035, Y035_HAEIN; hypothetical protein 38009 3431078 NTHI0043 Haemophilus influenzae 86-028NP hypothetical protein YP_247698.1 36354 R 281310 CDS YP_247699.1 68248587 3431079 38215..39993 1 NC_007146.2 Similar to: HI0036, Y036_HAEIN; ABC transporter ATP-binding protein 39993 3431079 NTHI0044 Haemophilus influenzae 86-028NP ABC transporter ATP-binding protein YP_247699.1 38215 D 281310 CDS YP_247700.2 229335608 3431080 40123..41178 1 NC_007146.2 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 41178 mreB 3431080 mreB Haemophilus influenzae 86-028NP rod shape-determining protein MreB YP_247700.2 40123 D 281310 CDS YP_247701.1 68248589 3431081 41258..42313 1 NC_007146.2 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 42313 mreC 3431081 mreC Haemophilus influenzae 86-028NP rod shape-determining protein MreC YP_247701.1 41258 D 281310 CDS YP_247702.1 68248590 3431082 42313..42801 1 NC_007146.2 Similar to: HI0039, MRED_HAEIN; rod shape-determining protein MreD 42801 mreD 3431082 mreD Haemophilus influenzae 86-028NP rod shape-determining protein MreD YP_247702.1 42313 D 281310 CDS YP_247703.1 68248591 3431083 complement(42852..43628) 1 NC_007146.2 Similar to: HI0040, Y040_HAEIN; hypothetical protein 43628 3431083 NTHI0048 Haemophilus influenzae 86-028NP hypothetical protein YP_247703.1 42852 R 281310 CDS YP_247704.1 68248592 3431084 complement(43638..44441) 1 NC_007146.2 exonuclease III; EXO III; removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 44441 xthA 3431084 xthA Haemophilus influenzae 86-028NP exonuclease III YP_247704.1 43638 R 281310 CDS YP_247705.1 68248593 3431085 complement(44489..45163) 1 NC_007146.2 pseudouridylate synthase; Uracil hydrolyase; Similar to: HI0042, Y042_HAEIN; pseudouridine synthase 45163 rluA2 3431085 rluA2 Haemophilus influenzae 86-028NP pseudouridine synthase YP_247705.1 44489 R 281310 CDS YP_247706.1 68248594 3431086 complement(45163..46227) 1 NC_007146.2 Similar to: HI0043, Y043_HAEIN; hypothetical protein 46227 3431086 NTHI0051 Haemophilus influenzae 86-028NP hypothetical protein YP_247706.1 45163 R 281310 CDS YP_247707.1 68248595 3431051 complement(46287..46949) 1 NC_007146.2 Similar to: HI0044, YCCA_HAEIN; FtsH-interacting integral membrane protein 46949 3431051 NTHI0052 Haemophilus influenzae 86-028NP FtsH-interacting integral membrane protein YP_247707.1 46287 R 281310 CDS YP_247708.1 68248596 3431053 complement(47276..47830) 1 NC_007146.2 Similar to: HI0045, YTFJ_HAEIN; hypothetical protein 47830 3431053 NTHI0053 Haemophilus influenzae 86-028NP hypothetical protein YP_247708.1 47276 R 281310 CDS YP_247709.1 68248597 3431054 47897..48259 1 NC_007146.2 Similar to: HI0046, PHNA_HAEIN; PhnA-like protein 48259 phnA 3431054 phnA Haemophilus influenzae 86-028NP PhnA-like protein YP_247709.1 47897 D 281310 CDS YP_247710.1 68248598 3431055 complement(48312..48950) 1 NC_007146.2 2-keto-4-hydroxyglutarate aldolase; KHG-aldolase; phospho-2-dehydro-3-deoxygluconate aldolase; phospho-2-keto-3-deoxygluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; KDPG-aldolase; catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 48950 eda 3431055 eda Haemophilus influenzae 86-028NP keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_247710.1 48312 R 281310 CDS YP_247711.1 68248599 3431056 complement(48959..50362) 1 NC_007146.2 glucuronate isomerase; Uronic isomerase; catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 50362 uxuC 3431056 uxuC Haemophilus influenzae 86-028NP glucuronate isomerase YP_247711.1 48959 R 281310 CDS YP_247712.1 68248600 3431057 complement(50372..51229) 1 NC_007146.2 Converts D-mannonate to D-mannuronate; D-mannonate oxidoreductase 51229 3431057 NTHI0057 Haemophilus influenzae 86-028NP D-mannonate oxidoreductase YP_247712.1 50372 R 281310 CDS YP_247713.1 68248601 3431059 complement(52192..53463) 1 NC_007146.2 Similar to: HI0050, Y050_HAEIN; TRAP-type C4-dicarboxylate transport system, large permease 53463 3431059 NTHI0060 Haemophilus influenzae 86-028NP TRAP-type C4-dicarboxylate transport system, large permease YP_247713.1 52192 R 281310 CDS YP_247714.1 68248602 3431060 complement(53473..53970) 1 NC_007146.2 Similar to: HI0051, Y051_HAEIN; TRAP-type C4-dicarboxylate transport system, small permease 53970 3431060 NTHI0061 Haemophilus influenzae 86-028NP TRAP-type C4-dicarboxylate transport system, small permease YP_247714.1 53473 R 281310 CDS YP_247715.1 68248603 3431061 complement(54009..54995) 1 NC_007146.2 Similar to: HI0052, Y052_HAEIN; TRAP-type C4-dicarboxylate transport system, periplasmic component 54995 3431061 NTHI0062 Haemophilus influenzae 86-028NP TRAP-type C4-dicarboxylate transport system, periplasmic component YP_247715.1 54009 R 281310 CDS YP_247716.1 68248604 3431062 complement(55022..56050) 1 NC_007146.2 Similar to: HI0053, Y053_HAEIN; hypothetical protein 56050 3431062 NTHI0063 Haemophilus influenzae 86-028NP hypothetical protein YP_247716.1 55022 R 281310 CDS YP_247717.1 68248605 3431063 56160..56960 1 NC_007146.2 Similar to: HI0054, UXUR_HAEIN; uxu operon regulator 56960 uxuR 3431063 uxuR Haemophilus influenzae 86-028NP uxu operon regulator YP_247717.1 56160 D 281310 CDS YP_247718.1 68248606 3431064 56988..58172 1 NC_007146.2 D-mannonate hydrolase; catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 58172 uxuA 3431064 uxuA Haemophilus influenzae 86-028NP mannonate dehydratase YP_247718.1 56988 D 281310 CDS YP_247719.1 68248607 3431065 complement(58225..58938) 1 NC_007146.2 possibly involved in tellurium resistance; Similar to: HI0056, YGDQ_HAEIN; membrane protein TerC 58938 3431065 NTHI0066 Haemophilus influenzae 86-028NP membrane protein TerC YP_247719.1 58225 R 281310 CDS YP_247720.1 68248608 3431066 complement(59036..60865) 1 NC_007146.2 UvrC; excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 60865 uvrC 3431066 uvrC Haemophilus influenzae 86-028NP excinuclease ABC subunit C YP_247720.1 59036 R 281310 CDS YP_247721.1 68248609 3431067 complement(60867..61631) 1 NC_007146.2 CMP-KDO synthetase; CMP-2-keto-3-deoxyoctulosonic acid synthetase; CKS; CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 61631 kdsB 3431067 kdsB Haemophilus influenzae 86-028NP 3-deoxy-manno-octulosonate cytidylyltransferase YP_247721.1 60867 R 281310 CDS YP_247722.1 68248610 3431087 complement(61702..62700) 1 NC_007146.2 lipid A 4'-kinase; transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 62700 lpxK 3431087 lpxK Haemophilus influenzae 86-028NP tetraacyldisaccharide 4'-kinase YP_247722.1 61702 R 281310 CDS YP_247723.1 68248611 3431088 complement(62773..64536) 1 NC_007146.2 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease protein 64536 msbA 3431088 msbA Haemophilus influenzae 86-028NP lipid transporter ATP-binding/permease protein YP_247723.1 62773 R 281310 CDS YP_247724.1 68248612 3431089 complement(64577..66943) 1 NC_007146.2 Similar to: HI0061, REC2_HAEIN; recombination protein 2 66943 rec2 3431089 rec2 Haemophilus influenzae 86-028NP recombination protein 2 YP_247724.1 64577 R 281310 CDS YP_247725.1 68248613 3431090 67202..67639 1 NC_007146.2 Similar to: HI0062, DKSA_HAEIN; DnaK suppressor protein 67639 dksA 3431090 dksA Haemophilus influenzae 86-028NP DnaK suppressor protein YP_247725.1 67202 D 281310 CDS YP_247726.1 68248614 3431091 67887..69245 1 NC_007146.2 Similar to: HI0063, PCNB_HAEIN; poly polymerase 69245 pcnB 3431091 pcnB Haemophilus influenzae 86-028NP poly polymerase YP_247726.1 67887 D 281310 CDS YP_247727.1 68248615 3431092 69254..69736 1 NC_007146.2 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; HPPK; 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; PPPK; Similar to: HI0064, HPPK_HAEIN; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 69736 folK 3431092 folK Haemophilus influenzae 86-028NP 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_247727.1 69254 D 281310 CDS YP_247728.1 68248616 3431093 69812..70288 1 NC_007146.2 Similar to: HI0065, YJEE_HAEIN; predicted ATPase activity; hypothetical protein 70288 3431093 NTHI0078 Haemophilus influenzae 86-028NP hypothetical protein YP_247728.1 69812 D 281310 CDS YP_247729.1 68248617 3431094 70296..71594 1 NC_007146.2 Similar to: HI0066, AMIB_HAEIN; N-acetylmuramoyl-L-alanine amidase 71594 amiB 3431094 amiB Haemophilus influenzae 86-028NP N-acetylmuramoyl-L-alanine amidase YP_247729.1 70296 D 281310 CDS YP_247730.1 68248618 3431095 71595..73484 1 NC_007146.2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 73484 mutL 3431095 mutL Haemophilus influenzae 86-028NP DNA mismatch repair protein YP_247730.1 71595 D 281310 CDS YP_247731.1 68248619 3431096 73492..74427 1 NC_007146.2 IPP transferase; isopentenyl-diphosphate:tRNA isopentenyltransferase; IPTase; IPPT; IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 74427 miaA 3431096 miaA Haemophilus influenzae 86-028NP tRNA delta(2)-isopentenylpyrophosphate transferase YP_247731.1 73492 D 281310 CDS YP_247732.1 68248620 3431097 74433..77378 1 NC_007146.2 glutamine-synthetase adenylyltransferase; ATASE; catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 77378 glnE 3431097 glnE Haemophilus influenzae 86-028NP bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_247732.1 74433 D 281310 CDS YP_247733.1 68248621 3431098 complement(77463..79139) 1 NC_007146.2 recombination protein N; Similar to: HI0070, RECN_HAEIN; DNA repair protein RecN 79139 recN 3431098 recN Haemophilus influenzae 86-028NP DNA repair protein RecN YP_247733.1 77463 R 281310 CDS YP_247734.1 68248622 3431099 complement(79251..80069) 1 NC_007146.2 Poly(P)/ATP NAD kinase; catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 80069 ppnK 3431099 ppnK Haemophilus influenzae 86-028NP inorganic polyphosphate/ATP-NAD kinase YP_247734.1 79251 R 281310 CDS YP_247735.1 68248623 3431100 80133..80837 1 NC_007146.2 HSP-70 cofactor; with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 80837 grpE 3431100 grpE Haemophilus influenzae 86-028NP heat shock protein GrpE YP_247735.1 80133 D 281310 CDS YP_247736.1 68248624 3431101 complement(80850..81194) 1 NC_007146.2 Similar to: HI0073, Y073_HAEIN; nucleotidyltransferase family; hypothetical protein 81194 3431101 NTHI0086 Haemophilus influenzae 86-028NP hypothetical protein YP_247736.1 80850 R 281310 CDS YP_247737.1 68248625 3431102 complement(81187..81627) 1 NC_007146.2 Similar to: HI0074, Y074_HAEIN; nucleotidyltransferase family; hypothetical protein 81627 3431102 NTHI0087 Haemophilus influenzae 86-028NP hypothetical protein YP_247737.1 81187 R 281310 CDS YP_247738.1 68248626 3431103 81908..84031 1 NC_007146.2 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 84031 nrdD 3431103 nrdD Haemophilus influenzae 86-028NP anaerobic ribonucleoside triphosphate reductase YP_247738.1 81908 D 281310 CDS YP_247739.1 68248627 3431104 84150..85010 1 NC_007146.2 TEII; Similar to: HI0076, TESB_HAEIN; acyl-CoA thioesterase 85010 tesB 3431104 tesB Haemophilus influenzae 86-028NP acyl-CoA thioesterase YP_247739.1 84150 D 281310 CDS YP_247740.1 68248628 3431105 complement(85171..86550) 1 NC_007146.2 cysteine--tRNA ligase; CysRS; catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 86550 cysS 3431105 cysS Haemophilus influenzae 86-028NP cysteinyl-tRNA synthetase YP_247740.1 85171 R 281310 CDS YP_247741.1 68248629 3431106 86653..87162 1 NC_007146.2 PPIase B; rotamase B; Similar to: HI0079, PPIB_HAEIN; peptidyl-prolyl cis-trans isomerase B 87162 ppiB 3431106 ppiB Haemophilus influenzae 86-028NP peptidyl-prolyl cis-trans isomerase B YP_247741.1 86653 D 281310 CDS YP_247742.1 68248630 3429430 87166..87597 1 NC_007146.2 Similar to: HI0080, YIFN_HAEIN; hypothetical protein 87597 3429430 NTHI0093 Haemophilus influenzae 86-028NP hypothetical protein YP_247742.1 87166 D 281310 CDS YP_247743.1 68248631 3429431 87739..88527 1 NC_007146.2 Similar to: HI0081, YJJV_HAEIN; deoxyribonuclease 88527 3429431 NTHI0095 Haemophilus influenzae 86-028NP deoxyribonuclease YP_247743.1 87739 D 281310 CDS YP_247744.1 68248632 3429432 88589..88846 1 NC_007146.2 hypothetical protein 88846 3429432 NTHI0096 Haemophilus influenzae 86-028NP hypothetical protein YP_247744.1 88589 D 281310 CDS YP_247745.1 68248633 3429433 88857..89132 1 NC_007146.2 hypothetical protein 89132 3429433 NTHI0097 Haemophilus influenzae 86-028NP hypothetical protein YP_247745.1 88857 D 281310 CDS YP_247746.1 68248634 3429434 complement(89182..89505) 1 NC_007146.2 TRX; Similar to: HI0084, THIO_HAEIN; thioredoxin 89505 trxA 3429434 trxA Haemophilus influenzae 86-028NP thioredoxin YP_247746.1 89182 R 281310 CDS YP_247747.1 68248635 3429435 complement(89625..90620) 1 NC_007146.2 Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthes; D-lactate dehydrogenase 90620 ddh 3429435 ddh Haemophilus influenzae 86-028NP D-lactate dehydrogenase YP_247747.1 89625 R 281310 CDS YP_247748.1 68248636 3429436 complement(90633..91778) 1 NC_007146.2 CGS; O-succinylhomoserine (Thiol)-lyase; catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity; cystathionine gamma-synthase 91778 metB 3429436 metB Haemophilus influenzae 86-028NP cystathionine gamma-synthase YP_247748.1 90633 R 281310 CDS YP_247749.1 68248637 3429440 92334..93170 1 NC_007146.2 chromosome partitioning ATPase 93170 3429440 NTHI0101 Haemophilus influenzae 86-028NP chromosome partitioning ATPase YP_247749.1 92334 D 281310 CDS YP_247750.1 68248638 3429441 93172..94527 1 NC_007146.2 Similar to: HI1574, DNAB_PASMU; replicative DNA helicase 94527 dnaB2 3429441 dnaB2 Haemophilus influenzae 86-028NP replicative DNA helicase YP_247750.1 93172 D 281310 CDS YP_247751.1 68248639 3429442 94520..96220 1 NC_007146.2 hypothetical protein 96220 3429442 NTHI0103 Haemophilus influenzae 86-028NP hypothetical protein YP_247751.1 94520 D 281310 CDS YP_247752.1 68248640 3429443 96220..96771 1 NC_007146.2 hypothetical protein 96771 3429443 NTHI0104 Haemophilus influenzae 86-028NP hypothetical protein YP_247752.1 96220 D 281310 CDS YP_247753.1 68248641 3429444 96921..98144 1 NC_007146.2 hypothetical protein 98144 3429444 NTHI0106 Haemophilus influenzae 86-028NP hypothetical protein YP_247753.1 96921 D 281310 CDS YP_247754.1 68248642 3429445 98441..99196 1 NC_007146.2 hypothetical protein 99196 3429445 NTHI0107 Haemophilus influenzae 86-028NP hypothetical protein YP_247754.1 98441 D 281310 CDS YP_247755.1 68248643 3429446 99196..99684 1 NC_007146.2 hypothetical protein 99684 3429446 NTHI0108 Haemophilus influenzae 86-028NP hypothetical protein YP_247755.1 99196 D 281310 CDS YP_247756.1 68248644 3429447 99930..100352 1 NC_007146.2 SSB; Helix-destabilizing protein; binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 100352 ssb2 3429447 ssb2 Haemophilus influenzae 86-028NP single-stranded DNA-binding protein YP_247756.1 99930 D 281310 CDS YP_247757.1 68248645 3429448 100379..100897 1 NC_007146.2 lipoprotein 100897 3429448 NTHI0110 Haemophilus influenzae 86-028NP lipoprotein YP_247757.1 100379 D 281310 CDS YP_247758.1 68248646 3429449 complement(101113..101670) 1 NC_007146.2 hypothetical protein 101670 3429449 NTHI0111 Haemophilus influenzae 86-028NP hypothetical protein YP_247758.1 101113 R 281310 CDS YP_247759.1 68248647 3429450 101746..103806 1 NC_007146.2 decatenates replicating daughter chromosomes; DNA topoisomerase III 103806 topB2 3429450 topB2 Haemophilus influenzae 86-028NP DNA topoisomerase III YP_247759.1 101746 D 281310 CDS YP_247760.1 68248648 3429451 104691..105119 1 NC_007146.2 hypothetical protein 105119 3429451 NTHI0113 Haemophilus influenzae 86-028NP hypothetical protein YP_247760.1 104691 D 281310 CDS YP_247761.1 68248649 3429452 105131..105223 1 NC_007146.2 hypothetical protein 105223 3429452 NTHI0114 Haemophilus influenzae 86-028NP hypothetical protein YP_247761.1 105131 D 281310 CDS YP_247762.1 68248650 3429453 105234..105875 1 NC_007146.2 hypothetical protein 105875 3429453 NTHI0115 Haemophilus influenzae 86-028NP hypothetical protein YP_247762.1 105234 D 281310 CDS YP_247763.1 68248651 3429454 105910..106317 1 NC_007146.2 hypothetical protein 106317 3429454 NTHI0116 Haemophilus influenzae 86-028NP hypothetical protein YP_247763.1 105910 D 281310 CDS YP_247764.1 68248652 3429455 106418..106888 1 NC_007146.2 Similar to: HI0952; DNA repair radC-like protein 106888 radC2 3429455 radC2 Haemophilus influenzae 86-028NP DNA repair radC-like protein YP_247764.1 106418 D 281310 CDS YP_247765.1 68248653 3429456 106981..107577 1 NC_007146.2 hypothetical protein 107577 3429456 NTHI0118 Haemophilus influenzae 86-028NP hypothetical protein YP_247765.1 106981 D 281310 CDS YP_247766.1 68248654 3429457 107635..108399 1 NC_007146.2 hypothetical protein 108399 3429457 NTHI0119 Haemophilus influenzae 86-028NP hypothetical protein YP_247766.1 107635 D 281310 CDS YP_247767.1 68248655 3429458 108498..109127 1 NC_007146.2 lipoprotein 109127 pilL 3429458 pilL Haemophilus influenzae 86-028NP lipoprotein YP_247767.1 108498 D 281310 CDS YP_247768.1 68248656 3429459 109131..109871 1 NC_007146.2 hypothetical protein 109871 3429459 NTHI0121 Haemophilus influenzae 86-028NP hypothetical protein YP_247768.1 109131 D 281310 CDS YP_247769.1 68248657 3429460 109850..110608 1 NC_007146.2 hypothetical protein 110608 3429460 NTHI0122 Haemophilus influenzae 86-028NP hypothetical protein YP_247769.1 109850 D 281310 CDS YP_247770.1 68248658 3429461 110624..111130 1 NC_007146.2 hypothetical protein 111130 3429461 NTHI0123 Haemophilus influenzae 86-028NP hypothetical protein YP_247770.1 110624 D 281310 CDS YP_247771.1 68248659 3429462 111127..113376 1 NC_007146.2 hypothetical protein 113376 3429462 NTHI0125 Haemophilus influenzae 86-028NP hypothetical protein YP_247771.1 111127 D 281310 CDS YP_247772.1 68248660 3429463 113695..114381 1 NC_007146.2 hypothetical protein 114381 3429463 NTHI0126 Haemophilus influenzae 86-028NP hypothetical protein YP_247772.1 113695 D 281310 CDS YP_247773.1 68248661 3429464 114512..114862 1 NC_007146.2 hypothetical protein 114862 3429464 NTHI0127 Haemophilus influenzae 86-028NP hypothetical protein YP_247773.1 114512 D 281310 CDS YP_247774.1 68248662 3429465 115131..115532 1 NC_007146.2 hypothetical protein 115532 3429465 NTHI0128 Haemophilus influenzae 86-028NP hypothetical protein YP_247774.1 115131 D 281310 CDS YP_247775.1 68248663 3429466 115552..115923 1 NC_007146.2 hypothetical protein 115923 3429466 NTHI0129 Haemophilus influenzae 86-028NP hypothetical protein YP_247775.1 115552 D 281310 CDS YP_247776.1 68248664 3429467 115935..116579 1 NC_007146.2 hypothetical protein 116579 3429467 NTHI0130 Haemophilus influenzae 86-028NP hypothetical protein YP_247776.1 115935 D 281310 CDS YP_247777.1 68248665 3429468 116579..117448 1 NC_007146.2 hypothetical protein 117448 3429468 NTHI0131 Haemophilus influenzae 86-028NP hypothetical protein YP_247777.1 116579 D 281310 CDS YP_247778.1 68248666 3429469 117459..118859 1 NC_007146.2 hypothetical protein 118859 3429469 NTHI0132 Haemophilus influenzae 86-028NP hypothetical protein YP_247778.1 117459 D 281310 CDS YP_247779.1 68248667 3429470 118869..119276 1 NC_007146.2 lipoprotein 119276 3429470 NTHI0133 Haemophilus influenzae 86-028NP lipoprotein YP_247779.1 118869 D 281310 CDS YP_247780.1 68248668 3429471 119292..122162 1 NC_007146.2 hypothetical protein 122162 3429471 NTHI0134 Haemophilus influenzae 86-028NP hypothetical protein YP_247780.1 119292 D 281310 CDS YP_247781.1 68248669 3429472 122170..122577 1 NC_007146.2 hypothetical protein 122577 3429472 NTHI0135 Haemophilus influenzae 86-028NP hypothetical protein YP_247781.1 122170 D 281310 CDS YP_247782.1 68248670 3429473 122587..122910 1 NC_007146.2 hypothetical protein 122910 3429473 NTHI0136 Haemophilus influenzae 86-028NP hypothetical protein YP_247782.1 122587 D 281310 CDS YP_247783.1 68248671 3429474 122919..124412 1 NC_007146.2 hypothetical protein 124412 3429474 NTHI0137 Haemophilus influenzae 86-028NP hypothetical protein YP_247783.1 122919 D 281310 CDS YP_247784.1 68248672 3429475 complement(124468..124797) 1 NC_007146.2 hypothetical protein 124797 3429475 NTHI0139 Haemophilus influenzae 86-028NP hypothetical protein YP_247784.1 124468 R 281310 CDS YP_247785.1 68248673 3429476 complement(124955..127960) 1 NC_007146.2 Similar to: TNP3_ECOLI; transposon Tn3 transposase 127960 tnpA 3429476 tnpA Haemophilus influenzae 86-028NP transposon Tn3 transposase YP_247785.1 124955 R 281310 CDS YP_247786.1 68248674 3429477 126925..127041 1 NC_007146.2 hypothetical protein 127041 3429477 NTHI0140 Haemophilus influenzae 86-028NP hypothetical protein YP_247786.1 126925 D 281310 CDS YP_247787.2 162960936 3429478 128088..128681 1 NC_007146.2 Similar to: TNR3_ECOLI; transposon Tn3 resolvase 128681 tnpR 3429478 tnpR Haemophilus influenzae 86-028NP transposon Tn3 resolvase YP_247787.2 128088 D 281310 CDS YP_001621483.1 162960937 5815435 128729..129589 1 NC_007146.2 beta-lactamase TEM 129589 5815435 NTHI2055 Haemophilus influenzae 86-028NP beta-lactamase TEM YP_001621483.1 128729 D 281310 CDS YP_247788.1 68248676 3429479 129813..129992 1 NC_007146.2 hypothetical protein 129992 3429479 NTHI0143 Haemophilus influenzae 86-028NP hypothetical protein YP_247788.1 129813 D 281310 CDS YP_247789.1 68248677 3429480 complement(130037..130444) 1 NC_007146.2 hypothetical protein 130444 3429480 NTHI0144 Haemophilus influenzae 86-028NP hypothetical protein YP_247789.1 130037 R 281310 CDS YP_247790.1 68248678 3429481 complement(130460..132460) 1 NC_007146.2 hypothetical protein 132460 3429481 NTHI0145 Haemophilus influenzae 86-028NP hypothetical protein YP_247790.1 130460 R 281310 CDS YP_247791.1 68248679 3429482 complement(132475..133416) 1 NC_007146.2 hypothetical protein 133416 3429482 NTHI0146 Haemophilus influenzae 86-028NP hypothetical protein YP_247791.1 132475 R 281310 CDS YP_247792.1 68248680 3429483 complement(133413..133856) 1 NC_007146.2 hypothetical protein 133856 3429483 NTHI0147 Haemophilus influenzae 86-028NP hypothetical protein YP_247792.1 133413 R 281310 CDS YP_247793.1 68248681 3429484 134168..134587 1 NC_007146.2 hypothetical protein 134587 3429484 NTHI0148 Haemophilus influenzae 86-028NP hypothetical protein YP_247793.1 134168 D 281310 CDS YP_247794.1 68248682 3429485 134672..134905 1 NC_007146.2 hypothetical protein 134905 3429485 NTHI0149 Haemophilus influenzae 86-028NP hypothetical protein YP_247794.1 134672 D 281310 CDS YP_247795.1 68248683 3429486 134908..135156 1 NC_007146.2 hypothetical protein 135156 3429486 NTHI0150 Haemophilus influenzae 86-028NP hypothetical protein YP_247795.1 134908 D 281310 CDS YP_247796.1 68248684 3429487 135160..135318 1 NC_007146.2 hypothetical protein 135318 3429487 NTHI0151 Haemophilus influenzae 86-028NP hypothetical protein YP_247796.1 135160 D 281310 CDS YP_247797.1 68248685 3429488 135449..136402 1 NC_007146.2 Similar to: TRC4_ECOLI; antirestriction protein 136402 traC 3429488 traC Haemophilus influenzae 86-028NP antirestriction protein YP_247797.1 135449 D 281310 CDS YP_247798.1 68248686 3429489 136506..137267 1 NC_007146.2 type I restriction enzyme M subunit 137267 3429489 NTHI0153 Haemophilus influenzae 86-028NP type I restriction enzyme M subunit YP_247798.1 136506 D 281310 CDS YP_247799.1 68248687 3429490 137493..138059 1 NC_007146.2 hypothetical protein 138059 3429490 NTHI0154 Haemophilus influenzae 86-028NP hypothetical protein YP_247799.1 137493 D 281310 CDS YP_247800.1 68248688 3429491 138099..138473 1 NC_007146.2 hypothetical protein 138473 3429491 NTHI0155 Haemophilus influenzae 86-028NP hypothetical protein YP_247800.1 138099 D 281310 CDS YP_247801.1 68248689 3429492 138463..139140 1 NC_007146.2 hypothetical protein 139140 3429492 NTHI0156 Haemophilus influenzae 86-028NP hypothetical protein YP_247801.1 138463 D 281310 CDS YP_247802.1 68248690 3429493 139118..139735 1 NC_007146.2 hypothetical protein 139735 3429493 NTHI0157 Haemophilus influenzae 86-028NP hypothetical protein YP_247802.1 139118 D 281310 CDS YP_247803.1 68248691 3429494 complement(139999..140598) 1 NC_007146.2 resolvase/integrase-like protein 140598 3429494 NTHI0158 Haemophilus influenzae 86-028NP resolvase/integrase-like protein YP_247803.1 139999 R 281310 CDS YP_247804.1 68248692 3429495 complement(140613..140804) 1 NC_007146.2 hypothetical protein 140804 3429495 NTHI0159 Haemophilus influenzae 86-028NP hypothetical protein YP_247804.1 140613 R 281310 CDS YP_247805.1 68248693 3429496 complement(141273..141527) 1 NC_007146.2 hypothetical protein 141527 3429496 NTHI0160 Haemophilus influenzae 86-028NP hypothetical protein YP_247805.1 141273 R 281310 CDS YP_247806.1 68248694 3429497 142718..143431 1 NC_007146.2 hypothetical protein 143431 3429497 NTHI0161 Haemophilus influenzae 86-028NP hypothetical protein YP_247806.1 142718 D 281310 CDS YP_247807.1 68248695 3429498 144151..145404 1 NC_007146.2 hypothetical protein 145404 3429498 NTHI0162 Haemophilus influenzae 86-028NP hypothetical protein YP_247807.1 144151 D 281310 CDS YP_247808.1 68248696 3429499 145547..147463 1 NC_007146.2 hypothetical protein 147463 3429499 NTHI0163 Haemophilus influenzae 86-028NP hypothetical protein YP_247808.1 145547 D 281310 CDS YP_247809.1 68248697 3429500 147524..148366 1 NC_007146.2 Similar to: XERC_PSESX; site-specific recombinase 148366 3429500 NTHI0164 Haemophilus influenzae 86-028NP site-specific recombinase YP_247809.1 147524 D 281310 CDS YP_247810.1 68248698 3429502 complement(149016..150293) 1 NC_007146.2 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 150293 thrC 3429502 thrC Haemophilus influenzae 86-028NP threonine synthase YP_247810.1 149016 R 281310 CDS YP_247811.1 68248699 3429503 complement(150336..151280) 1 NC_007146.2 HK; catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 151280 thrB 3429503 thrB Haemophilus influenzae 86-028NP homoserine kinase YP_247811.1 150336 R 281310 CDS YP_247812.1 68248700 3429504 complement(151293..153740) 1 NC_007146.2 bifunctional protein including aspartokinase, homoserine dehydrogenase; AK-HD; multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 153740 thrA 3429504 thrA Haemophilus influenzae 86-028NP bifunctional aspartokinase I/homoserine dehydrogenase I YP_247812.1 151293 R 281310 CDS YP_247813.1 68248701 3429505 154064..154777 1 NC_007146.2 Similar to: HI0090, Y090_HAEIN; hypothetical protein 154777 3429505 NTHI0168 Haemophilus influenzae 86-028NP hypothetical protein YP_247813.1 154064 D 281310 CDS YP_247814.1 68248702 3429506 complement(154817..155953) 1 NC_007146.2 Similar to: HI0091, GRK_HAEIN; glycerate kinase 155953 grk 3429506 grk Haemophilus influenzae 86-028NP glycerate kinase YP_247814.1 154817 R 281310 CDS YP_247815.1 68248703 3429507 complement(155962..157221) 1 NC_007146.2 Similar to: HI0092, Y092_HAEIN; hypothetical protein 157221 3429507 NTHI0171 Haemophilus influenzae 86-028NP hypothetical protein YP_247815.1 155962 R 281310 CDS YP_247816.1 68248704 3429508 complement(157343..158449) 1 NC_007146.2 Similar to: HI0093, Y093_HAEIN; hypothetical protein 158449 3429508 NTHI0172 Haemophilus influenzae 86-028NP hypothetical protein YP_247816.1 157343 R 281310 CDS YP_247817.1 68248705 3429509 complement(158651..158971) 1 NC_007146.2 Similar to: HI0094, Y094_HAEIN; hypothetical protein 158971 3429509 NTHI0173 Haemophilus influenzae 86-028NP hypothetical protein YP_247817.1 158651 R 281310 CDS YP_247818.1 68248706 3429511 complement(159322..160077) 1 NC_007146.2 Similar to: HI0095, Y095_HAEIN; hypothetical protein 160077 3429511 NTHI0175 Haemophilus influenzae 86-028NP hypothetical protein YP_247818.1 159322 R 281310 CDS YP_247819.1 68248707 3429512 160278..160559 1 NC_007146.2 Similar to: HI0096, Y096_HAEIN; hypothetical protein 160559 3429512 NTHI0176 Haemophilus influenzae 86-028NP hypothetical protein YP_247819.1 160278 D 281310 CDS YP_247820.1 68248708 3429513 160711..161709 1 NC_007146.2 Major ferric iron binding protein; Iron-regulated 40 kDa protein; MIRP; Fe(3+)-binding protein; Similar to: HI0097, FBPA_HAEIN; iron-utilization periplasmic protein hFbpA 161709 hitA 3429513 hitA Haemophilus influenzae 86-028NP iron-utilization periplasmic protein hFbpA YP_247820.1 160711 D 281310 CDS YP_247821.1 68248709 3429514 161827..163347 1 NC_007146.2 Similar to: HI0098, FBB2_HAEIN; iron ABC transporter permease 163347 hitB 3429514 hitB Haemophilus influenzae 86-028NP iron ABC transporter permease YP_247821.1 161827 D 281310 CDS YP_247822.1 68248710 3429515 163349..164404 1 NC_007146.2 Similar to: HI0099, FBC2_HAEIN; iron-utilization ATP-binding protein hFbpC 164404 hitC 3429515 hitC Haemophilus influenzae 86-028NP iron-utilization ATP-binding protein hFbpC YP_247822.1 163349 D 281310 CDS YP_247823.1 68248711 3429516 complement(164439..165119) 1 NC_007146.2 Similar to: HI0100, Y100_HAEIN; D-alanyl-D-alanine carboxypeptidase 165119 3429516 NTHI0181 Haemophilus influenzae 86-028NP D-alanyl-D-alanine carboxypeptidase YP_247823.1 164439 R 281310 CDS YP_247824.1 68248712 3429517 complement(165121..166254) 1 NC_007146.2 SDAP; dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica; succinyl-diaminopimelate desuccinylase 166254 dapE 3429517 dapE Haemophilus influenzae 86-028NP succinyl-diaminopimelate desuccinylase YP_247824.1 165121 R 281310 CDS YP_247825.1 68248713 3429518 complement(166282..166626) 1 NC_007146.2 Similar to: HI0103, YFFB_HAEIN; hypothetical protein 166626 3429518 NTHI0184 Haemophilus influenzae 86-028NP hypothetical protein YP_247825.1 166282 R 281310 CDS YP_247826.1 68248714 3429519 complement(166705..168600) 1 NC_007146.2 Heat shock protein htpG; High temperature protein G; molecular chaperone; heat shock protein 90 168600 htpG 3429519 htpG Haemophilus influenzae 86-028NP heat shock protein 90 YP_247826.1 166705 R 281310 CDS YP_247827.1 68248715 3429520 168812..169651 1 NC_007146.2 Similar to: HI0105, YBGI_HAEIN; NIF3-like protein 169651 3429520 NTHI0186 Haemophilus influenzae 86-028NP NIF3-like protein YP_247827.1 168812 D 281310 CDS YP_247828.1 68248716 3429521 169825..172197 1 NC_007146.2 type I restriction-modification system, methyltransferase subunit 172197 hsdM1 3429521 hsdM1 Haemophilus influenzae 86-028NP type I restriction-modification system, methyltransferase subunit YP_247828.1 169825 D 281310 CDS YP_247829.1 68248717 3429522 172380..173789 1 NC_007146.2 transcription regulator 173789 3429522 NTHI0190 Haemophilus influenzae 86-028NP transcription regulator YP_247829.1 172380 D 281310 CDS YP_247830.1 68248718 3429523 173961..175211 1 NC_007146.2 type I site-specific restriction-modification system, S subunit 175211 hsdS1 3429523 hsdS1 Haemophilus influenzae 86-028NP type I site-specific restriction-modification system, S subunit YP_247830.1 173961 D 281310 CDS YP_247831.1 68248719 3429524 175311..178337 1 NC_007146.2 type I site-specific restriction-modification system, R subunit 178337 hsdR1 3429524 hsdR1 Haemophilus influenzae 86-028NP type I site-specific restriction-modification system, R subunit YP_247831.1 175311 D 281310 CDS YP_247832.1 68248720 3429525 complement(178562..179941) 1 NC_007146.2 Fifty-four homolog; Similar to: HI0106, SR54_HAEIN; Signal recognition particle protein 179941 ffh 3429525 ffh Haemophilus influenzae 86-028NP Signal recognition particle protein YP_247832.1 178562 R 281310 CDS YP_247833.1 68248721 3429526 180192..181484 1 NC_007146.2 Similar to: HI0107, YFJD_HAEIN; Mg2+ and Co2+ transporter 181484 corB 3429526 corB Haemophilus influenzae 86-028NP Mg2+ and Co2+ transporter YP_247833.1 180192 D 281310 CDS YP_247834.1 68248722 3429527 181505..182383 1 NC_007146.2 Similar to: HI0108, YJJP_ECOLI; hypothetical protein 182383 3429527 NTHI0197 Haemophilus influenzae 86-028NP hypothetical protein YP_247834.1 181505 D 281310 CDS YP_247835.1 68248723 3429528 182385..182864 1 NC_007146.2 Similar to: HI0108, YJJP_HAEIN; hypothetical protein 182864 3429528 NTHI0198 Haemophilus influenzae 86-028NP hypothetical protein YP_247835.1 182385 D 281310 CDS YP_247836.1 68248724 3429529 complement(182954..183295) 1 NC_007146.2 Similar to: HI0109, Y109_HAEIN; hypothetical protein 183295 3429529 NTHI0199 Haemophilus influenzae 86-028NP hypothetical protein YP_247836.1 182954 R 281310 CDS YP_247837.1 68248725 3429530 183462..184751 1 NC_007146.2 Serine--tRNA ligase; SerRS; catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 184751 serS 3429530 serS Haemophilus influenzae 86-028NP seryl-tRNA synthetase YP_247837.1 183462 D 281310 CDS YP_247838.1 68248726 3429531 185086..185715 1 NC_007146.2 Similar to: HI0111, GT_HAEIN; glutathione S-transferase 185715 gst 3429531 gst Haemophilus influenzae 86-028NP glutathione S-transferase YP_247838.1 185086 D 281310 CDS YP_247839.1 68248727 3429532 complement(185727..186023) 1 NC_007146.2 hypothetical protein 186023 3429532 NTHI0201_1 Haemophilus influenzae 86-028NP hypothetical protein YP_247839.1 185727 R 281310 CDS YP_247840.1 68248728 3429533 186076..188313 1 NC_007146.2 Similar to: HI0113, HXC1_HAEIN; hemin receptor 188313 hemR 3429533 hemR Haemophilus influenzae 86-028NP hemin receptor YP_247840.1 186076 D 281310 CDS YP_247841.1 68248729 3429541 complement(195361..197496) 1 NC_007146.2 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 197496 rlmL 3429541 rlmL Haemophilus influenzae 86-028NP 23S rRNA m(2)G2445 methyltransferase YP_247841.1 195361 R 281310 CDS YP_247842.1 68248730 3429543 197889..198998 1 NC_007146.2 murein hydrolase A; Mlt38; membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 198998 mltA 3429543 mltA Haemophilus influenzae 86-028NP murein transglycosylase A YP_247842.1 197889 D 281310 CDS YP_247843.1 68248731 3429544 198998..199768 1 NC_007146.2 homolog of dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; Similar to: HI0118, YGDL_HAEIN; hypothetical protein 199768 3429544 NTHI0206 Haemophilus influenzae 86-028NP hypothetical protein YP_247843.1 198998 D 281310 CDS YP_247844.1 68248732 3429545 199946..200947 1 NC_007146.2 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic component 200947 znuA 3429545 znuA Haemophilus influenzae 86-028NP high-affinity zinc transporter periplasmic component YP_247844.1 199946 D 281310 CDS YP_247845.1 68248733 3429546 complement(200997..201503) 1 NC_007146.2 Similar to: HI0120, Y120_HAEIN; hypothetical protein 201503 3429546 NTHI0209 Haemophilus influenzae 86-028NP hypothetical protein YP_247845.1 200997 R 281310 CDS YP_247846.1 68248734 3429547 complement(201616..202974) 1 NC_007146.2 Murein peptide ligase; Similar to: HI0121, MPL_HAEIN; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 202974 mpl 3429547 mpl Haemophilus influenzae 86-028NP UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_247846.1 201616 R 281310 CDS YP_247847.1 68248735 3429548 complement(203359..204546) 1 NC_007146.2 CBL; beta-cystathionase; cysteine lyase; catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 204546 metC 3429548 metC Haemophilus influenzae 86-028NP cystathionine beta-lyase YP_247847.1 203359 R 281310 CDS YP_247848.1 68248736 3429549 204677..205285 1 NC_007146.2 Similar to: TSAA_BUCAP; peroxiredoxin 205285 tsaA 3429549 tsaA Haemophilus influenzae 86-028NP peroxiredoxin YP_247848.1 204677 D 281310 CDS YP_247849.1 68248737 3429550 205386..205943 1 NC_007146.2 phosphatidylglycerophosphate synthase; PGP synthase; Similar to: HI0123, PGSA_HAEIN; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 205943 pgsA 3429550 pgsA Haemophilus influenzae 86-028NP CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_247849.1 205386 D 281310 CDS YP_247850.1 68248738 3429554 complement(206507..207037) 1 NC_007146.2 pyrophosphate phospho-hydrolase; PPase; catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 207037 ppa 3429554 ppa Haemophilus influenzae 86-028NP inorganic pyrophosphatase YP_247850.1 206507 R 281310 CDS YP_247851.1 68248739 3429555 207271..208587 1 NC_007146.2 Similar to: HI0125, YJCD_HAEIN; hypothetical protein 208587 3429555 NTHI0215 Haemophilus influenzae 86-028NP hypothetical protein YP_247851.1 207271 D 281310 CDS YP_247852.1 68248740 3429556 208810..209451 1 NC_007146.2 uridine monophosphokinase; cytidine monophosphokinase; functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 209451 udk 3429556 udk Haemophilus influenzae 86-028NP uridine kinase YP_247852.1 208810 D 281310 CDS YP_247853.1 68248741 3429557 209460..210047 1 NC_007146.2 dCTP deaminase; Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 210047 dcd 3429557 dcd Haemophilus influenzae 86-028NP deoxycytidine triphosphate deaminase YP_247853.1 209460 D 281310 CDS YP_247854.1 68248742 3429558 210051..211226 1 NC_007146.2 Similar to: HI0134, Y134_HAEIN; hypothetical protein 211226 3429558 NTHI0220 Haemophilus influenzae 86-028NP hypothetical protein YP_247854.1 210051 D 281310 CDS YP_247855.1 68248743 3429559 211226..212434 1 NC_007146.2 Similar to: HI0135, SOTB_HAEIN; sugar efflux transporter 212434 3429559 NTHI0221 Haemophilus influenzae 86-028NP sugar efflux transporter YP_247855.1 211226 D 281310 CDS YP_247856.1 68248744 3429560 complement(212495..214009) 1 NC_007146.2 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 214009 engA 3429560 engA Haemophilus influenzae 86-028NP GTP-binding protein EngA YP_247856.1 212495 R 281310 CDS YP_247857.1 68248745 3429563 complement(214691..215458) 1 NC_007146.2 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 215458 dnaQ 3429563 dnaQ Haemophilus influenzae 86-028NP DNA polymerase III subunit epsilon YP_247857.1 214691 R 281310 CDS YP_247858.1 68248746 3429564 215519..215983 1 NC_007146.2 RNase HI; An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 215983 rnhA 3429564 rnhA Haemophilus influenzae 86-028NP ribonuclease H YP_247858.1 215519 D 281310 CDS YP_247859.1 68248747 3429565 216249..217346 1 NC_007146.2 OMP P2; Similar to: HI0139, OP27_HAEIN; outer membrane protein P2 217346 ompP2 3429565 ompP2 Haemophilus influenzae 86-028NP outer membrane protein P2 YP_247859.1 216249 D 281310 CDS YP_247860.1 68248748 3429566 complement(217543..218688) 1 NC_007146.2 GlcNAc 6-P deacetylase; catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 218688 nagA 3429566 nagA Haemophilus influenzae 86-028NP N-acetylglucosamine-6-phosphate deacetylase YP_247860.1 217543 R 281310 CDS YP_247861.1 68248749 3429567 complement(218825..219637) 1 NC_007146.2 glucosamine-6-phosphate isomerase; GNPDA; GlcN6P deaminase; catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 219637 nagB 3429567 nagB Haemophilus influenzae 86-028NP glucosamine-6-phosphate deaminase YP_247861.1 218825 R 281310 CDS YP_247862.1 68248750 3429568 complement(219973..220854) 1 NC_007146.2 N-acetylneuraminic acid aldolase; N-acetylneuraminate pyruvate-lyase; sialic acid lyase; sialate lyase; sialic acid aldolase; catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 220854 nanA 3429568 nanA Haemophilus influenzae 86-028NP N-acetylneuraminate lyase YP_247862.1 219973 R 281310 CDS YP_247863.1 68248751 3429569 complement(220865..221731) 1 NC_007146.2 Similar to: HI0143, Y143_HAEIN; HTH-type transcriptional regulator 221731 3429569 NTHI0229 Haemophilus influenzae 86-028NP HTH-type transcriptional regulator YP_247863.1 220865 R 281310 CDS YP_247864.1 68248752 3429570 complement(221724..222626) 1 NC_007146.2 ManNAc kinase; catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 222626 nanK 3429570 nanK Haemophilus influenzae 86-028NP N-acetylmannosamine kinase YP_247864.1 221724 R 281310 CDS YP_247865.1 68248753 3429571 complement(222671..223357) 1 NC_007146.2 ManNAc-6-P epimerase; Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 223357 nanE 3429571 nanE Haemophilus influenzae 86-028NP N-acetylmannosamine-6-phosphate 2-epimerase YP_247865.1 222671 R 281310 CDS YP_247866.1 68248754 3429572 223707..224696 1 NC_007146.2 Similar to: HI0146, Y146_HAEIN; sialic acid transporter, TRAP-type C4-dicarboxylate transport system, periplasmic component 224696 3429572 NTHI0232 Haemophilus influenzae 86-028NP sialic acid transporter, TRAP-type C4-dicarboxylate transport system, periplasmic component YP_247866.1 223707 D 281310 CDS YP_247867.1 68248755 3429573 224761..226611 1 NC_007146.2 Similar to: HI0147, Y147_HAEIN; hypothetical protein 226611 siaT 3429573 siaT Haemophilus influenzae 86-028NP hypothetical protein YP_247867.1 224761 D 281310 CDS YP_247868.1 68248756 3429574 226775..227914 1 NC_007146.2 Similar to: HI0148, YJHT_HAEIN; N-acetylneuraminic acid mutarotase 227914 3429574 NTHI0235 Haemophilus influenzae 86-028NP N-acetylneuraminic acid mutarotase YP_247868.1 226775 D 281310 CDS YP_247869.1 68248757 3429575 228076..228510 1 NC_007146.2 Similar to: HI0149; protein-S-isoprenylcysteine methyltransferase 228510 3429575 NTHI0236 Haemophilus influenzae 86-028NP protein-S-isoprenylcysteine methyltransferase YP_247869.1 228076 D 281310 CDS YP_247870.1 68248758 3429576 complement(228552..229439) 1 NC_007146.2 Similar to: HI0150, HFLC_HAEIN; hypothetical protein 229439 hflC 3429576 hflC Haemophilus influenzae 86-028NP hypothetical protein YP_247870.1 228552 R 281310 CDS YP_247871.1 68248759 3429577 complement(229439..230671) 1 NC_007146.2 Similar to: HI0151, HFLK_HAEIN; HflK 230671 hflK 3429577 hflK Haemophilus influenzae 86-028NP HflK YP_247871.1 229439 R 281310 CDS YP_247872.1 68248760 3429578 complement(230781..231488) 1 NC_007146.2 Similar to: HI0152, Y152_HAEIN; 4'-phosphopantetheinyl transferase 231488 3429578 NTHI0240 Haemophilus influenzae 86-028NP 4'-phosphopantetheinyl transferase YP_247872.1 230781 R 281310 CDS YP_247873.1 68248761 3429579 complement(231548..232879) 1 NC_007146.2 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 232879 dcuB2 3429579 dcuB2 Haemophilus influenzae 86-028NP anaerobic C4-dicarboxylate transporter YP_247873.1 231548 R 281310 CDS YP_247874.1 68248762 3429580 complement(233083..233313) 1 NC_007146.2 ACP; carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 233313 acpP 3429580 acpP Haemophilus influenzae 86-028NP acyl carrier protein YP_247874.1 233083 R 281310 CDS YP_247875.1 68248763 3429581 complement(233573..234301) 1 NC_007146.2 3-ketoacyl-acyl carrier protein reductase; catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 234301 fabG 3429581 fabG Haemophilus influenzae 86-028NP 3-ketoacyl-ACP reductase YP_247875.1 233573 R 281310 CDS YP_247876.1 68248764 3429582 complement(234318..235256) 1 NC_007146.2 MCT; Similar to: HI0156, FABD_HAEIN; ACP S-malonyltransferase 235256 fabD 3429582 fabD Haemophilus influenzae 86-028NP ACP S-malonyltransferase YP_247876.1 234318 R 281310 CDS YP_247877.1 68248765 3429583 complement(235756..236706) 1 NC_007146.2 beta-ketoacyl-ACP synthase III; KAS III; FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 236706 fabH 3429583 fabH Haemophilus influenzae 86-028NP 3-oxoacyl-ACP synthase YP_247877.1 235756 R 281310 CDS YP_247878.1 68248766 3429584 complement(236892..237062) 1 NC_007146.2 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 237062 rpmF 3429584 rpmF Haemophilus influenzae 86-028NP 50S ribosomal protein L32 YP_247878.1 236892 R 281310 CDS YP_247879.1 68248767 3429585 complement(237085..237609) 1 NC_007146.2 Similar to: HI0159, YCED_HAEIN; hypothetical protein 237609 3429585 NTHI0249 Haemophilus influenzae 86-028NP hypothetical protein YP_247879.1 237085 R 281310 CDS YP_247880.1 68248768 3429586 237766..238638 1 NC_007146.2 phosphatidylserine decarboxylase alpha chain; phosphatidylserine decarboxylase beta chain; catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 238638 psd 3429586 psd Haemophilus influenzae 86-028NP phosphatidylserine decarboxylase YP_247880.1 237766 D 281310 CDS YP_247881.1 68248769 3429587 complement(238747..240117) 1 NC_007146.2 GR; GRase; catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 240117 gor 3429587 gor Haemophilus influenzae 86-028NP glutathione reductase YP_247881.1 238747 R 281310 CDS YP_247882.1 68248770 3429588 complement(240333..240932) 1 NC_007146.2 Similar to: HI0162, YAJG_HAEIN; lipoprotein 240932 3429588 NTHI0252 Haemophilus influenzae 86-028NP lipoprotein YP_247882.1 240333 R 281310 CDS YP_247883.1 68248771 3429590 241628..242971 1 NC_007146.2 Na(+)-translocating NQR subunit A; Na(+)-NQR subunit A; NQR complex subunit A; NQR-1 subunit A; uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A 242971 nqrA 3429590 nqrA Haemophilus influenzae 86-028NP Na(+)-translocating NADH-quinone reductase subunit A YP_247883.1 241628 D 281310 CDS YP_247884.1 68248772 3429591 242974..244209 1 NC_007146.2 Na(+)-translocating NQR subunit B; Na(+)-NQR subunit B; NQR complex subunit B; NQR-1 subunit B; uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B 244209 nqrB 3429591 nqrB Haemophilus influenzae 86-028NP Na(+)-translocating NADH-quinone reductase subunit B YP_247884.1 242974 D 281310 CDS YP_247885.1 68248773 3429592 244202..244936 1 NC_007146.2 Na(+)-translocating NQR subunit C; Na(+)-NQR subunit C; NQR complex subunit C; NQR-1 subunit C; uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C 244936 nqrC 3429592 nqrC Haemophilus influenzae 86-028NP Na(+)-translocating NADH-quinone reductase subunit C YP_247885.1 244202 D 281310 CDS YP_247886.1 68248774 3429593 244936..245562 1 NC_007146.2 Na(+)-translocating NQR subunit D; Na(+)-NQR subunit D; NQR complex subunit D; NQR-1 subunit D; Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D 245562 nqrD 3429593 nqrD Haemophilus influenzae 86-028NP Na(+)-translocating NADH-quinone reductase subunit D YP_247886.1 244936 D 281310 CDS YP_247887.1 68248775 3429594 245566..246162 1 NC_007146.2 Na(+)-translocating NQR subunit E; Na(+)-NQR subunit E; NQR complex subunit E; NQR-1 subunit E; Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Na(+)-translocating NADH-quinone reductase subunit E 246162 nqrE 3429594 nqrE Haemophilus influenzae 86-028NP Na(+)-translocating NADH-quinone reductase subunit E YP_247887.1 245566 D 281310 CDS YP_247888.1 68248776 3429595 246175..247410 1 NC_007146.2 Na(+)-translocating NQR subunit F; Na(+)-NQR subunit F; NQR complex subunit F; NQR-1 subunit F; uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F 247410 nqrF 3429595 nqrF Haemophilus influenzae 86-028NP Na(+)-translocating NADH-quinone reductase subunit F YP_247888.1 246175 D 281310 CDS YP_247889.1 68248777 3429596 247554..248594 1 NC_007146.2 Similar to: HI0172, APBE_HAEIN; thiamine biosynthesis lipoprotein ApbE 248594 apbE 3429596 apbE Haemophilus influenzae 86-028NP thiamine biosynthesis lipoprotein ApbE YP_247889.1 247554 D 281310 CDS YP_247890.1 68248778 3429597 248597..248857 1 NC_007146.2 Similar to: HI0173, Y173_HAEIN; hypothetical protein 248857 3429597 NTHI0261 Haemophilus influenzae 86-028NP hypothetical protein YP_247890.1 248597 D 281310 CDS YP_247891.1 68248779 3429598 248932..250125 1 NC_007146.2 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 250125 mnmA 3429598 mnmA Haemophilus influenzae 86-028NP tRNA-specific 2-thiouridylase MnmA YP_247891.1 248932 D 281310 CDS YP_247892.1 68248780 3429599 complement(250169..250903) 1 NC_007146.2 Similar to: HI0175, YFIH_HAEIN; hypothetical protein 250903 3429599 NTHI0263 Haemophilus influenzae 86-028NP hypothetical protein YP_247892.1 250169 R 281310 CDS YP_247893.1 68248781 3429600 complement(250905..251879) 1 NC_007146.2 pseudouridylate synthase; Uracil hydrolyase; responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 251879 rluD 3429600 rluD Haemophilus influenzae 86-028NP 23S rRNA pseudouridine synthase D YP_247893.1 250905 R 281310 CDS YP_247894.1 68248782 3429601 251987..252775 1 NC_007146.2 Similar to: HI0177, YFIO_HAEIN; hypothetical protein 252775 3429601 NTHI0266 Haemophilus influenzae 86-028NP hypothetical protein YP_247894.1 251987 D 281310 CDS YP_247895.1 68248783 3429602 complement(252854..253336) 1 NC_007146.2 Similar to: HI0178, Y178_HAEIN; hypothetical protein 253336 3429602 NTHI0267 Haemophilus influenzae 86-028NP hypothetical protein YP_247895.1 252854 R 281310 CDS YP_247896.1 68248784 3429603 complement(253368..254108) 1 NC_007146.2 PFL-activating enzyme; activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 254108 pflA 3429603 pflA Haemophilus influenzae 86-028NP pyruvate formate lyase-activating enzyme 1 YP_247896.1 253368 R 281310 CDS YP_247897.1 68248785 3429604 complement(254233..256551) 1 NC_007146.2 pyruvate formate-lyase; Similar to: HI0180, PFLB_HAEIN; formate acetyltransferase 256551 pflB 3429604 pflB Haemophilus influenzae 86-028NP formate acetyltransferase YP_247897.1 254233 R 281310 CDS YP_247898.1 68248786 3429605 complement(256583..257437) 1 NC_007146.2 Similar to: HI0181, FOCA_HAEIN; formate transporter 257437 focA 3429605 focA Haemophilus influenzae 86-028NP formate transporter YP_247898.1 256583 R 281310 CDS YP_247899.1 68248787 3429606 257942..258856 1 NC_007146.2 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 258856 3429606 NTHI0273 Haemophilus influenzae 86-028NP N-acetyl-D-glucosamine kinase YP_247899.1 257942 D 281310 CDS YP_247900.1 68248788 3429607 259035..260480 1 NC_007146.2 Similar to: HI0183, YAAJ_HAEIN; Na+/alanine symporter 260480 3429607 NTHI0274 Haemophilus influenzae 86-028NP Na+/alanine symporter YP_247900.1 259035 D 281310 CDS YP_247901.1 68248789 3429608 complement(260665..261492) 1 NC_007146.2 Similar to: HI0184, YAIM_HAEIN; esterase 261492 3429608 NTHI0275 Haemophilus influenzae 86-028NP esterase YP_247901.1 260665 R 281310 CDS YP_247902.1 68248790 3429610 262760..263167 1 NC_007146.2 Similar to: HI0186, Y186_HAEIN; HTH-type transcriptional regulator 263167 3429610 NTHI0278 Haemophilus influenzae 86-028NP HTH-type transcriptional regulator YP_247902.1 262760 D 281310 CDS YP_247903.1 68248791 3429611 263325..263612 1 NC_007146.2 Similar to: TATA_HAEIN; Sec-independent protein translocase protein TatA/E 263612 tatA 3429611 tatA Haemophilus influenzae 86-028NP Sec-independent protein translocase protein TatA/E YP_247903.1 263325 D 281310 CDS YP_247904.1 68248792 3429612 263616..264176 1 NC_007146.2 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 264176 tatB 3429612 tatB Haemophilus influenzae 86-028NP sec-independent translocase YP_247904.1 263616 D 281310 CDS YP_247905.1 68248793 3429613 264186..264956 1 NC_007146.2 Similar to: HI0188, TATC_HAEIN; Sec-independent protein translocase protein TatC 264956 tatC 3429613 tatC Haemophilus influenzae 86-028NP Sec-independent protein translocase protein TatC YP_247905.1 264186 D 281310 CDS YP_247906.1 68248794 3429614 265317..266666 1 NC_007146.2 NADP-GDH; converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 266666 gdhA 3429614 gdhA Haemophilus influenzae 86-028NP glutamate dehydrogenase YP_247906.1 265317 D 281310 CDS YP_247907.1 68248795 3429615 complement(266774..267214) 1 NC_007146.2 ferric uptake regulator; Similar to: HI0190, FUR_HAEIN; ferric uptake regulation protein 267214 fur 3429615 fur Haemophilus influenzae 86-028NP ferric uptake regulation protein YP_247907.1 266774 R 281310 CDS YP_247908.1 68248796 3429616 complement(267243..267767) 1 NC_007146.2 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 267767 fldA 3429616 fldA Haemophilus influenzae 86-028NP flavodoxin FldA YP_247908.1 267243 R 281310 CDS YP_247909.1 68248797 3429617 complement(267864..268727) 1 NC_007146.2 Similar to: HI0193, Y193_HAEIN; esterase 268727 3429617 NTHI0286 Haemophilus influenzae 86-028NP esterase YP_247909.1 267864 R 281310 CDS YP_247910.1 68248798 3429618 268717..269322 1 NC_007146.2 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 269322 seqA 3429618 seqA Haemophilus influenzae 86-028NP replication initiation regulator SeqA YP_247910.1 268717 D 281310 CDS YP_247911.1 68248799 3429619 269325..270683 1 NC_007146.2 OSB-CoA synthetase; O-succinylbenzoyl-CoA synthetase; Similar to: HI0194, MENE_HAEIN; O-succinylbenzoic acid--CoA ligase 270683 menE 3429619 menE Haemophilus influenzae 86-028NP O-succinylbenzoic acid--CoA ligase YP_247911.1 269325 D 281310 CDS YP_247912.1 68248800 3429620 270711..274049 1 NC_007146.2 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 274049 3429620 NTHI0291 Haemophilus influenzae 86-028NP potassium efflux protein KefA YP_247912.1 270711 D 281310 CDS YP_247913.1 68248801 3429621 274059..275132 1 NC_007146.2 5-enolpyruvylshikimate-3-phosphate phospholyase; catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 275132 aroC 3429621 aroC Haemophilus influenzae 86-028NP chorismate synthase YP_247913.1 274059 D 281310 CDS YP_247914.1 68248802 3429622 275305..276165 1 NC_007146.2 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 276165 mepA 3429622 mepA Haemophilus influenzae 86-028NP penicillin-insensitive murein endopeptidase YP_247914.1 275305 D 281310 CDS YP_247915.1 68248803 3429623 276183..276950 1 NC_007146.2 Similar to: HI0198, YFCA_HAEIN; hypothetical protein 276950 3429623 NTHI0295 Haemophilus influenzae 86-028NP hypothetical protein YP_247915.1 276183 D 281310 CDS YP_247916.1 68248804 3429624 276997..277953 1 NC_007146.2 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 277953 msbB 3429624 msbB Haemophilus influenzae 86-028NP lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_247916.1 276997 D 281310 CDS YP_247917.1 68248805 3429625 278080..279051 1 NC_007146.2 selenophosphate synthetase; selenium donor protein; catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 279051 selD 3429625 selD Haemophilus influenzae 86-028NP selenophosphate synthetase YP_247917.1 278080 D 281310 CDS YP_247918.1 68248806 3429626 complement(279160..279510) 1 NC_007146.2 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 279510 rplS 3429626 rplS Haemophilus influenzae 86-028NP 50S ribosomal protein L19 YP_247918.1 279160 R 281310 CDS YP_247919.1 68248807 3429627 complement(279547..280287) 1 NC_007146.2 M1G-methyltransferase; tRNA [GM37] methyltransferase; methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 280287 trmD 3429627 trmD Haemophilus influenzae 86-028NP tRNA (guanine-N(1)-)-methyltransferase YP_247919.1 279547 R 281310 CDS YP_247920.1 68248808 3429628 complement(280325..280852) 1 NC_007146.2 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 280852 rimM 3429628 rimM Haemophilus influenzae 86-028NP 16S rRNA-processing protein RimM YP_247920.1 280325 R 281310 CDS YP_247921.1 68248809 3429629 complement(280897..281145) 1 NC_007146.2 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 281145 rpsP 3429629 rpsP Haemophilus influenzae 86-028NP 30S ribosomal protein S16 YP_247921.1 280897 R 281310 CDS YP_247922.1 68248810 3429630 281425..282210 1 NC_007146.2 Similar to: HI0205, Y205_HAEIN; hypothetical protein 282210 3429630 NTHI0302 Haemophilus influenzae 86-028NP hypothetical protein YP_247922.1 281425 D 281310 CDS YP_247923.1 68248811 3429631 282233..284044 1 NC_007146.2 5'-nucleotidase; Similar to: HI0206, 5NTD_HAEIN; NAD nucleotidase 284044 nadN 3429631 nadN Haemophilus influenzae 86-028NP NAD nucleotidase YP_247923.1 282233 D 281310 CDS YP_247924.1 68248812 3429632 284329..284871 1 NC_007146.2 SK; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 284871 aroK 3429632 aroK Haemophilus influenzae 86-028NP shikimate kinase YP_247924.1 284329 D 281310 CDS YP_247925.1 68248813 3429633 284891..285979 1 NC_007146.2 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 285979 aroB 3429633 aroB Haemophilus influenzae 86-028NP 3-dehydroquinate synthase YP_247925.1 284891 D 281310 CDS YP_247926.1 68248814 3429634 285981..286841 1 NC_007146.2 deoxyadenosyl-methyltransferase; DNA adenine methyltransferase; M.HindIV; Similar to: HI0209, DMA_HAEIN; DNA adenine methylase 286841 dam 3429634 dam Haemophilus influenzae 86-028NP DNA adenine methylase YP_247926.1 285981 D 281310 CDS YP_247927.1 68248815 3429635 287806..287913 1 NC_007146.2 hypothetical protein 287913 3429635 NTHI0307_1 Haemophilus influenzae 86-028NP hypothetical protein YP_247927.1 287806 D 281310 CDS YP_247928.1 68248816 3429636 complement(287932..288657) 1 NC_007146.2 Similar to: HI0211, PGPB_HAEIN; phosphatidylglycerophosphatase B 288657 pgpB 3429636 pgpB Haemophilus influenzae 86-028NP phosphatidylglycerophosphatase B YP_247928.1 287932 R 281310 CDS YP_247929.1 68248817 3429637 288703..289377 1 NC_007146.2 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 289377 ribA 3429637 ribA Haemophilus influenzae 86-028NP GTP cyclohydrolase II YP_247929.1 288703 D 281310 CDS YP_247930.1 68248818 3429638 complement(289693..291237) 1 NC_007146.2 Similar to: HI0213, Y213_HAEIN; ABC-type oligopeptide transport system, periplasmic component 291237 3429638 NTHI0310 Haemophilus influenzae 86-028NP ABC-type oligopeptide transport system, periplasmic component YP_247930.1 289693 R 281310 CDS YP_247931.1 68248819 3429639 complement(291230..291592) 1 NC_007146.2 hypothetical protein 291592 3429639 NTHI0311 Haemophilus influenzae 86-028NP hypothetical protein YP_247931.1 291230 R 281310 CDS YP_247932.1 68248820 3429640 291711..293756 1 NC_007146.2 Similar to: HI0214, OPDA_HAEIN; oligopeptidase A 293756 prlC 3429640 prlC Haemophilus influenzae 86-028NP oligopeptidase A YP_247932.1 291711 D 281310 CDS YP_247933.1 68248821 3429641 293988..295532 1 NC_007146.2 M protein; Similar to: HI1287, T1MP_ECOLI; type I restriction-modification system methyltransferase subunit 295532 hsdM2 3429641 hsdM2 Haemophilus influenzae 86-028NP type I restriction-modification system methyltransferase subunit YP_247933.1 293988 D 281310 CDS YP_247934.1 68248822 3429642 295617..296789 1 NC_007146.2 S protein; Similar to: HI0216, T1SI_HAEIN; type I restriction-modification system specificity protein 296789 hsdS2 3429642 hsdS2 Haemophilus influenzae 86-028NP type I restriction-modification system specificity protein YP_247934.1 295617 D 281310 CDS YP_247935.1 68248823 3429643 296791..297945 1 NC_007146.2 Similar to: PRRC_ECOLI; anticodon nuclease 297945 prrC 3429643 prrC Haemophilus influenzae 86-028NP anticodon nuclease YP_247935.1 296791 D 281310 CDS YP_247936.1 68248824 3429644 297948..298946 1 NC_007146.2 DNA binding protein 298946 3429644 NTHI0317 Haemophilus influenzae 86-028NP DNA binding protein YP_247936.1 297948 D 281310 CDS YP_247937.1 68248825 3429645 298957..302040 1 NC_007146.2 R protein; Similar to: T1R1_ECOLI; type I restriction-modification system 302040 hsdR2 3429645 hsdR2 Haemophilus influenzae 86-028NP type I restriction-modification system YP_247937.1 298957 D 281310 CDS YP_247938.1 68248826 3429646 complement(302187..302816) 1 NC_007146.2 Similar to: HI0219, YKGB_HAEIN; hypothetical protein 302816 3429646 NTHI0319 Haemophilus influenzae 86-028NP hypothetical protein YP_247938.1 302187 R 281310 CDS YP_247939.1 68248827 3429647 complement(303030..304871) 1 NC_007146.2 Similar to: HI1651, ARCB_HAEIN; aerobic respiration control sensor protein ArcB 304871 arcB 3429647 arcB Haemophilus influenzae 86-028NP aerobic respiration control sensor protein ArcB YP_247939.1 303030 R 281310 CDS YP_247940.1 68248828 3429648 complement(304940..305584) 1 NC_007146.2 Similar to: HI0220.2, Y22A_HAEIN; uracil-DNA glycosylase 305584 3429648 NTHI0322 Haemophilus influenzae 86-028NP uracil-DNA glycosylase YP_247940.1 304940 R 281310 CDS YP_247941.1 68248829 3429653 complement(311636..312544) 1 NC_007146.2 Biotin--protein ligase; catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 312544 birA 3429653 birA Haemophilus influenzae 86-028NP biotin--protein ligase YP_247941.1 311636 R 281310 CDS YP_247942.1 68248830 3429654 312671..314137 1 NC_007146.2 IMP dehydrogenase; IMPDH; IMPD; catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 314137 guaB 3429654 guaB Haemophilus influenzae 86-028NP inosine 5'-monophosphate dehydrogenase YP_247942.1 312671 D 281310 CDS YP_247943.1 68248831 3429655 314247..315818 1 NC_007146.2 glutamine amidotransferase; GMP synthetase; contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 315818 guaA 3429655 guaA Haemophilus influenzae 86-028NP GMP synthase YP_247943.1 314247 D 281310 CDS YP_247944.1 68248832 3429656 complement(315880..316782) 1 NC_007146.2 Similar to: HI0223, Y223_HAEIN; hypothetical protein 316782 3429656 NTHI0327 Haemophilus influenzae 86-028NP hypothetical protein YP_247944.1 315880 R 281310 CDS YP_247945.1 68248833 3429657 316845..317351 1 NC_007146.2 Similar to: HI0224, Y224_HAEIN; transcriptional regulator 317351 3429657 NTHI0328 Haemophilus influenzae 86-028NP transcriptional regulator YP_247945.1 316845 D 281310 CDS YP_247946.1 68248834 3429658 complement(317390..318592) 1 NC_007146.2 Sodium/proton antiporter 1; exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 318592 nhaA 3429658 nhaA Haemophilus influenzae 86-028NP pH-dependent sodium/proton antiporter YP_247946.1 317390 R 281310 CDS YP_247947.1 68248835 3429659 318780..320090 1 NC_007146.2 branched-chain amino acid uptake carrier; Similar to: HI0226, BRNQ_HAEIN; branched chain amino acid ABC transporter carrier protein 320090 brnQ 3429659 brnQ Haemophilus influenzae 86-028NP branched chain amino acid ABC transporter carrier protein YP_247947.1 318780 D 281310 CDS YP_247948.1 68248836 3429660 complement(320198..320665) 1 NC_007146.2 Similar to: HI0227, YHCH_HAEIN; hypothetical protein 320665 3429660 NTHI0332 Haemophilus influenzae 86-028NP hypothetical protein YP_247948.1 320198 R 281310 CDS YP_247949.1 68248837 3429661 complement(320692..321138) 1 NC_007146.2 Similar to: HI0228, Y228_HAEIN; hypothetical protein 321138 3429661 NTHI0333 Haemophilus influenzae 86-028NP hypothetical protein YP_247949.1 320692 R 281310 CDS YP_247950.1 68248838 3429662 321411..323540 1 NC_007146.2 polynucleotide phosphorylase; PNPase; Similar to: HI0229, PNP_HAEIN; polynucleotide phosphorylase 323540 pnp 3429662 pnp Haemophilus influenzae 86-028NP polynucleotide phosphorylase YP_247950.1 321411 D 281310 CDS YP_247951.1 68248839 3429663 323622..324566 1 NC_007146.2 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 324566 nlpL 3429663 nlpL Haemophilus influenzae 86-028NP lipoprotein NlpI YP_247951.1 323622 D 281310 CDS YP_247952.1 68248840 3429664 324686..326527 1 NC_007146.2 ATP-dependent RNA helicase DeaD homolog; Similar to: HI0231, DEAD_HAEIN; cold-shock DEAD-box protein A-like protein 326527 deaD 3429664 deaD Haemophilus influenzae 86-028NP cold-shock DEAD-box protein A-like protein YP_247952.1 324686 D 281310 CDS YP_247953.1 68248841 3429665 326705..328093 1 NC_007146.2 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 328093 3429665 NTHI0338 Haemophilus influenzae 86-028NP transglycosylase YP_247953.1 326705 D 281310 CDS YP_247954.1 68248842 3429666 328098..328250 1 NC_007146.2 Similar to: HI0233; hypothetical protein 328250 3429666 NTHI0339 Haemophilus influenzae 86-028NP hypothetical protein YP_247954.1 328098 D 281310 CDS YP_247955.1 68248843 3429667 complement(328384..328680) 1 NC_007146.2 Similar to: HI0234; hypothetical protein 328680 3429667 NTHI0340 Haemophilus influenzae 86-028NP hypothetical protein YP_247955.1 328384 R 281310 CDS YP_247956.1 68248844 3429668 complement(328737..328946) 1 NC_007146.2 Similar to: HI0235, YHDL_HAEIN; hypothetical protein 328946 3429668 NTHI0342 Haemophilus influenzae 86-028NP hypothetical protein YP_247956.1 328737 R 281310 CDS YP_247957.1 68248845 3429669 complement(329014..329364) 1 NC_007146.2 Similar to: HI0236, ARSC_HAEIN; arsenate reductase 329364 arsC 3429669 arsC Haemophilus influenzae 86-028NP arsenate reductase YP_247957.1 329014 R 281310 CDS YP_247958.1 68248846 3429670 329443..330492 1 NC_007146.2 Similar to: PERM_HAEIN; permease PerM-like protein 330492 perM 3429670 perM Haemophilus influenzae 86-028NP permease PerM-like protein YP_247958.1 329443 D 281310 CDS YP_247959.1 68248847 3429671 complement(330606..331583) 1 NC_007146.2 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 331583 secF 3429671 secF Haemophilus influenzae 86-028NP preprotein translocase subunit SecF YP_247959.1 330606 R 281310 CDS YP_247960.1 68248848 3429672 complement(331591..333441) 1 NC_007146.2 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 333441 secD 3429672 secD Haemophilus influenzae 86-028NP preprotein translocase subunit SecD YP_247960.1 331591 R 281310 CDS YP_247961.1 68248849 3429673 complement(333511..333804) 1 NC_007146.2 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 333804 yajC 3429673 yajC Haemophilus influenzae 86-028NP preprotein translocase subunit YajC YP_247961.1 333511 R 281310 CDS YP_247962.1 68248850 3429674 complement(333912..334133) 1 NC_007146.2 Similar to: HI0242, Y242_HAEIN; redox protein, regulator of disulfide bond formation 334133 3429674 NTHI0348 Haemophilus influenzae 86-028NP redox protein, regulator of disulfide bond formation YP_247962.1 333912 R 281310 CDS YP_247963.1 68248851 3429675 complement(334130..334648) 1 NC_007146.2 Similar to: HI0243, Y243_HAEIN; hypothetical protein 334648 3429675 NTHI0349 Haemophilus influenzae 86-028NP hypothetical protein YP_247963.1 334130 R 281310 CDS YP_247964.1 68248852 3429676 complement(334713..335861) 1 NC_007146.2 tRNA-guanine transglycosylase; guanine insertion enzyme; Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 335861 tgt 3429676 tgt Haemophilus influenzae 86-028NP queuine tRNA-ribosyltransferase YP_247964.1 334713 R 281310 CDS YP_247965.1 68248853 3429677 complement(336206..337297) 1 NC_007146.2 queuosine biosynthesis protein QueA; Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 337297 queA 3429677 queA Haemophilus influenzae 86-028NP S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_247965.1 336206 R 281310 CDS YP_247966.1 68248854 3429678 complement(337421..337867) 1 NC_007146.2 Similar to: HI0246, Y246_HAEIN; hypothetical protein 337867 3429678 NTHI0353 Haemophilus influenzae 86-028NP hypothetical protein YP_247966.1 337421 R 281310 CDS YP_247967.1 68248855 3429679 complement(338010..342188) 1 NC_007146.2 Similar to: HI0990, HAP_HAEIN; adhesion and penetration protein Hap 342188 hap 3429679 hap Haemophilus influenzae 86-028NP adhesion and penetration protein Hap YP_247967.1 338010 R 281310 CDS YP_247968.1 68248856 3429680 complement(342506..345337) 1 NC_007146.2 UvrA; excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 345337 uvrA 3429680 uvrA Haemophilus influenzae 86-028NP excinuclease ABC subunit A YP_247968.1 342506 R 281310 CDS YP_247969.1 68248857 3429681 345490..345996 1 NC_007146.2 SSB; Helix-destabilizing protein; binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 345996 ssb 3429681 ssb Haemophilus influenzae 86-028NP single-stranded DNA-binding protein YP_247969.1 345490 D 281310 CDS YP_247970.1 68248858 3429682 complement(346174..346968) 1 NC_007146.2 Similar to: HI0251, TONB_HAEIN; TonB 346968 tonB 3429682 tonB Haemophilus influenzae 86-028NP TonB YP_247970.1 346174 R 281310 CDS YP_247971.1 68248859 3429683 complement(346978..347421) 1 NC_007146.2 Similar to: HI0252, EXBD_HAEIN; biopolymer transport protein 347421 exbD 3429683 exbD Haemophilus influenzae 86-028NP biopolymer transport protein YP_247971.1 346978 R 281310 CDS YP_247972.1 68248860 3429684 complement(347425..347877) 1 NC_007146.2 Similar to: HI0253, EXBB_HAEIN; transport protein ExbB 347877 exbB 3429684 exbB Haemophilus influenzae 86-028NP transport protein ExbB YP_247972.1 347425 R 281310 CDS YP_247973.1 68248861 3429685 complement(348046..348513) 1 NC_007146.2 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 348513 bcp 3429685 bcp Haemophilus influenzae 86-028NP thioredoxin-dependent thiol peroxidase YP_247973.1 348046 R 281310 CDS YP_247974.1 68248862 3429686 348614..349510 1 NC_007146.2 DHDPS; catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 349510 dapA 3429686 dapA Haemophilus influenzae 86-028NP dihydrodipicolinate synthase YP_247974.1 348614 D 281310 CDS YP_247975.1 68248863 3429687 349621..350250 1 NC_007146.2 Similar to: HI0256, Y256_HAEIN; lipoprotein 350250 3429687 NTHI0363 Haemophilus influenzae 86-028NP lipoprotein YP_247975.1 349621 D 281310 CDS YP_247976.1 68248864 3429688 350440..350763 1 NC_007146.2 Similar to: HI0257, YFIA_HAEIN; hypothetical protein 350763 3429688 NTHI0364 Haemophilus influenzae 86-028NP hypothetical protein YP_247976.1 350440 D 281310 CDS YP_247977.1 68248865 3429690 complement(351477..352415) 1 NC_007146.2 Similar to: HI0258, Y258_HAEIN; UDP-galactose--lipooligosaccharide galactosyltransferase 352415 lgtC 3429690 lgtC Haemophilus influenzae 86-028NP UDP-galactose--lipooligosaccharide galactosyltransferase YP_247977.1 351477 R 281310 CDS YP_247978.1 68248866 3429691 complement(352483..353070) 1 NC_007146.2 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 353070 orfM 3429691 orfM Haemophilus influenzae 86-028NP deoxyribonucleotide triphosphate pyrophosphatase YP_247978.1 352483 R 281310 CDS YP_247979.1 68248867 3429692 complement(353082..353807) 1 NC_007146.2 KDO kinase; catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position; 3-deoxy-D-manno-octulosonic-acid kinase 353807 kdkA 3429692 kdkA Haemophilus influenzae 86-028NP 3-deoxy-D-manno-octulosonic-acid kinase YP_247979.1 353082 R 281310 CDS YP_247980.1 68248868 3429693 353884..354927 1 NC_007146.2 Similar to: HI0261, Y261_HAEIN; ADP-heptose--lipooligosaccharide heptosyltransferase I 354927 opsX 3429693 opsX Haemophilus influenzae 86-028NP ADP-heptose--lipooligosaccharide heptosyltransferase I YP_247980.1 353884 D 281310 CDS YP_247981.1 68248869 3429694 355249..357378 1 NC_007146.2 heme:hemopexin utilization protein C; Similar to: HI0262, HXC2_HAEIN; heme-hemopexin utilization protein C 357378 hxuC 3429694 hxuC Haemophilus influenzae 86-028NP heme-hemopexin utilization protein C YP_247981.1 355249 D 281310 CDS YP_247982.1 68248870 3429695 357454..359151 1 NC_007146.2 heme:hemopexin utilization protein B; Similar to: HI0263, HXB2_HAEIN; heme/hemopexin-binding protein B 359151 hxuB 3429695 hxuB Haemophilus influenzae 86-028NP heme/hemopexin-binding protein B YP_247982.1 357454 D 281310 CDS YP_247983.1 68248871 3429696 359163..361928 1 NC_007146.2 heme:hemopexin utilization protein A; Similar to: HI0264, HXA2_HAEIN; heme/hemopexin-binding protein A 361928 hxuA 3429696 hxuA Haemophilus influenzae 86-028NP heme/hemopexin-binding protein A YP_247983.1 359163 D 281310 CDS YP_247984.1 68248872 3429697 complement(362024..362380) 1 NC_007146.2 DHNA; Similar to: HI0265, FOLB_HAEIN; dihydroneopterin aldolase 362380 folB 3429697 folB Haemophilus influenzae 86-028NP dihydroneopterin aldolase YP_247984.1 362024 R 281310 CDS YP_247985.1 68248873 3429698 362463..363062 1 NC_007146.2 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 363062 3429698 NTHI0373 Haemophilus influenzae 86-028NP glycerol-3-phosphate acyltransferase PlsY YP_247985.1 362463 D 281310 CDS YP_247986.1 68248874 3429699 363104..364807 1 NC_007146.2 Similar to: HI0267, NARQ_HAEIN; nitrate/nitrite sensor protein NarQ 364807 narQ 3429699 narQ Haemophilus influenzae 86-028NP nitrate/nitrite sensor protein NarQ YP_247986.1 363104 D 281310 CDS YP_247987.1 68248875 3429700 364817..365842 1 NC_007146.2 UDP-N-acetylmuramate dehydrogenase; catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 365842 murB 3429700 murB Haemophilus influenzae 86-028NP UDP-N-acetylenolpyruvoylglucosamine reductase YP_247987.1 364817 D 281310 CDS YP_247988.1 68248876 3429701 365968..366813 1 NC_007146.2 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 366813 rpoH 3429701 rpoH Haemophilus influenzae 86-028NP RNA polymerase factor sigma-32 YP_247988.1 365968 D 281310 CDS YP_247989.1 68248877 3429703 complement(367280..368146) 1 NC_007146.2 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 368146 djlA 3429703 djlA Haemophilus influenzae 86-028NP Dna-J like membrane chaperone protein YP_247989.1 367280 R 281310 CDS YP_247990.1 68248878 3429704 complement(368225..368866) 1 NC_007146.2 OPRT; OPRTase; involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 368866 pyrE 3429704 pyrE Haemophilus influenzae 86-028NP orotate phosphoribosyltransferase YP_247990.1 368225 R 281310 CDS YP_247991.1 68248879 3429705 complement(368890..369606) 1 NC_007146.2 RNase PH; tRNA nucleotidyltransferase; RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 369606 rph 3429705 rph Haemophilus influenzae 86-028NP ribonuclease PH YP_247991.1 368890 R 281310 CDS YP_247992.1 68248880 3429707 complement(369907..371349) 1 NC_007146.2 glutamate--tRNA ligase; GluRS; Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 371349 gltX 3429707 gltX Haemophilus influenzae 86-028NP glutamyl-tRNA synthetase YP_247992.1 369907 R 281310 CDS YP_247993.1 68248881 3429712 372099..373754 1 NC_007146.2 Similar to: HI0275, Y275_HAEIN; PE-tn-6--lipooligosaccharide phosphorylethanolamine transferase 373754 lpt6 3429712 lpt6 Haemophilus influenzae 86-028NP PE-tn-6--lipooligosaccharide phosphorylethanolamine transferase YP_247993.1 372099 D 281310 CDS YP_247994.1 68248882 3429713 complement(373772..374581) 1 NC_007146.2 RNase BN; RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 374581 rbn 3429713 rbn Haemophilus influenzae 86-028NP ribonuclease BN YP_247994.1 373772 R 281310 CDS YP_247995.1 68248883 3429714 complement(374578..375063) 1 NC_007146.2 Similar to: HI0277, Y277_HAEIN; hypothetical protein 375063 3429714 NTHI0386 Haemophilus influenzae 86-028NP hypothetical protein YP_247995.1 374578 R 281310 CDS YP_247996.1 68248884 3429715 complement(375066..375728) 1 NC_007146.2 Similar to: HI0278, YIIM_HAEIN; hypothetical protein 375728 3429715 NTHI0387 Haemophilus influenzae 86-028NP hypothetical protein YP_247996.1 375066 R 281310 CDS YP_247997.2 161761279 3429716 375964..376722 1 NC_007146.2 UrdPase; UPase; catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 376722 udp 3429716 udp Haemophilus influenzae 86-028NP uridine phosphorylase YP_247997.2 375964 D 281310 CDS YP_247998.1 68248886 3429717 complement(376948..378264) 1 NC_007146.2 Similar to: HI0281, Y281_HAEIN; metabolite transport protein 378264 3429717 NTHI0390 Haemophilus influenzae 86-028NP metabolite transport protein YP_247998.1 376948 R 281310 CDS YP_247999.1 68248887 3429718 complement(378320..379063) 1 NC_007146.2 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase 379063 3429718 NTHI0391 Haemophilus influenzae 86-028NP acyl-CoA thioester hydrolase YP_247999.1 378320 R 281310 CDS YP_248000.1 68248888 3429719 complement(379124..380830) 1 NC_007146.2 SHCHC synthase; alpha-ketoglutarate decarboxylase; KDC; SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 380830 menD 3429719 menD Haemophilus influenzae 86-028NP 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_248000.1 379124 R 281310 CDS YP_248001.1 68248889 3429720 complement(380846..382117) 1 NC_007146.2 isochorismate mutase; synthesizes isochorismate acid from chorismate; menaquinone-specific isochorismate synthase 382117 menF 3429720 menF Haemophilus influenzae 86-028NP menaquinone-specific isochorismate synthase YP_248001.1 380846 R 281310 CDS YP_248002.1 68248890 3429721 382274..383488 1 NC_007146.2 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 383488 aspC3 3429721 aspC3 Haemophilus influenzae 86-028NP aminotransferase YP_248002.1 382274 D 281310 CDS YP_248003.1 68248891 3429722 383605..384861 1 NC_007146.2 tryptophan permease; Similar to: HI0287, MTR_HAEIN; tryptophan-specific transport protein 384861 mtr 3429722 mtr Haemophilus influenzae 86-028NP tryptophan-specific transport protein YP_248003.1 383605 D 281310 CDS YP_248004.1 68248892 3429723 complement(384970..386337) 1 NC_007146.2 L-serine deaminase; SDH; L-SD; Similar to: HI0288, SDHL_HAEIN; L-serine dehydratase 386337 sdaA 3429723 sdaA Haemophilus influenzae 86-028NP L-serine dehydratase YP_248004.1 384970 R 281310 CDS YP_248005.1 68248893 3429724 complement(386372..387610) 1 NC_007146.2 Similar to: HI0289, SDAC_HAEIN; serine transporter 387610 sdaC 3429724 sdaC Haemophilus influenzae 86-028NP serine transporter YP_248005.1 386372 R 281310 CDS YP_248006.1 68248894 3429725 complement(387833..390001) 1 NC_007146.2 Similar to: HI0290, Y290_HAEIN; cation-transporting ATPase 390001 3429725 NTHI0399 Haemophilus influenzae 86-028NP cation-transporting ATPase YP_248006.1 387833 R 281310 CDS YP_248007.1 68248895 3429727 390841..391227 1 NC_007146.2 Similar to: HI0293, Y293_HAEIN; heavy metal dependent transcriptional regulator 391227 3429727 NTHI0403 Haemophilus influenzae 86-028NP heavy metal dependent transcriptional regulator YP_248007.1 390841 D 281310 CDS YP_248008.1 68248896 3429728 complement(391241..391558) 1 NC_007146.2 Met regulon regulatory protein metJ; when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 391558 metJ 3429728 metJ Haemophilus influenzae 86-028NP transcriptional repressor protein MetJ YP_248008.1 391241 R 281310 CDS YP_248009.1 68248897 3429729 391802..393064 1 NC_007146.2 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 393064 rho 3429729 rho Haemophilus influenzae 86-028NP transcription termination factor Rho YP_248009.1 391802 D 281310 CDS YP_248010.1 68248898 3429730 complement(393118..393810) 1 NC_007146.2 Similar to: HI0296, LEP4_HAEIN; type 4 prepilin-like protein specific leader peptidase 393810 pilD 3429730 pilD Haemophilus influenzae 86-028NP type 4 prepilin-like protein specific leader peptidase YP_248010.1 393118 R 281310 CDS YP_248011.1 68248899 3429731 complement(393807..395027) 1 NC_007146.2 Similar to: HI0297, HOFC_HAEIN; type IV pilin secretion protein 395027 pilC 3429731 pilC Haemophilus influenzae 86-028NP type IV pilin secretion protein YP_248011.1 393807 R 281310 CDS YP_248012.1 68248900 3429732 complement(395024..396418) 1 NC_007146.2 Similar to: HI0298, HOFB_HAEIN; type IV pilin secretion protein 396418 pilB 3429732 pilB Haemophilus influenzae 86-028NP type IV pilin secretion protein YP_248012.1 395024 R 281310 CDS YP_248013.1 68248901 3429733 complement(396415..396864) 1 NC_007146.2 Similar to: HI0299, PPDD_HAEIN; Type IV pilin subunit protein 396864 pilA 3429733 pilA Haemophilus influenzae 86-028NP Type IV pilin subunit protein YP_248013.1 396415 R 281310 CDS YP_248014.1 68248902 3429734 396979..397539 1 NC_007146.2 Similar to: HI0300, AMPD_HAEIN; N-acetyl-anhydromuranmyl-L-alanine amidase 397539 ampD 3429734 ampD Haemophilus influenzae 86-028NP N-acetyl-anhydromuranmyl-L-alanine amidase YP_248014.1 396979 D 281310 CDS YP_248015.1 68248903 3429735 398161..399060 1 NC_007146.2 Similar to: HI0301, CORC_HAEIN; magnesium and cobalt efflux protein CorC 399060 corC 3429735 corC Haemophilus influenzae 86-028NP magnesium and cobalt efflux protein CorC YP_248015.1 398161 D 281310 CDS YP_248016.1 68248904 3429736 399044..400612 1 NC_007146.2 ALP N-acyltransferase; Copper homeostasis protein CutE homolog; Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 400612 lnt 3429736 lnt Haemophilus influenzae 86-028NP apolipoprotein N-acyltransferase YP_248016.1 399044 D 281310 CDS YP_248017.1 68248905 3429737 400662..401399 1 NC_007146.2 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 401399 3429737 NTHI0414 Haemophilus influenzae 86-028NP 16S ribosomal RNA methyltransferase RsmE YP_248017.1 400662 D 281310 CDS YP_248018.1 68248906 3429738 401396..401956 1 NC_007146.2 Similar to: HI0304, YQGE_HAEIN; hypothetical protein 401956 3429738 NTHI0415 Haemophilus influenzae 86-028NP hypothetical protein YP_248018.1 401396 D 281310 CDS YP_248019.1 68248907 3429739 401956..402375 1 NC_007146.2 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 402375 ruvX 3429739 ruvX Haemophilus influenzae 86-028NP Holliday junction resolvase-like protein YP_248019.1 401956 D 281310 CDS YP_248020.1 68248908 3429741 403545..404756 1 NC_007146.2 Similar to: INTA_ECOLI; prophage CP4-57-like integrase 404756 3429741 NTHI0419 Haemophilus influenzae 86-028NP prophage CP4-57-like integrase YP_248020.1 403545 D 281310 CDS YP_248021.1 68248909 3429742 complement(404793..405227) 1 NC_007146.2 hypothetical protein 405227 3429742 NTHI0420 Haemophilus influenzae 86-028NP hypothetical protein YP_248021.1 404793 R 281310 CDS YP_248022.1 68248910 3429743 405340..405762 1 NC_007146.2 hypothetical protein 405762 3429743 NTHI0421 Haemophilus influenzae 86-028NP hypothetical protein YP_248022.1 405340 D 281310 CDS YP_248023.1 68248911 3429744 405771..406544 1 NC_007146.2 hypothetical protein 406544 3429744 NTHI0422 Haemophilus influenzae 86-028NP hypothetical protein YP_248023.1 405771 D 281310 CDS YP_248024.1 68248912 3429745 407079..407270 1 NC_007146.2 hypothetical protein 407270 3429745 NTHI0423 Haemophilus influenzae 86-028NP hypothetical protein YP_248024.1 407079 D 281310 CDS YP_248025.1 68248913 3429746 407319..407471 1 NC_007146.2 hypothetical protein 407471 3429746 NTHI0424 Haemophilus influenzae 86-028NP hypothetical protein YP_248025.1 407319 D 281310 CDS YP_248026.1 68248914 3429747 complement(407638..408528) 1 NC_007146.2 hypothetical protein 408528 3429747 NTHI0425 Haemophilus influenzae 86-028NP hypothetical protein YP_248026.1 407638 R 281310 CDS YP_248027.1 68248915 3429748 409189..410004 1 NC_007146.2 P5CR; P5C reductase; catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 410004 proC 3429748 proC Haemophilus influenzae 86-028NP pyrroline-5-carboxylate reductase YP_248027.1 409189 D 281310 CDS YP_248028.1 68248916 3429749 410004..411170 1 NC_007146.2 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 411170 hcaT 3429749 hcaT Haemophilus influenzae 86-028NP 3-phenylpropionic acid transporter YP_248028.1 410004 D 281310 CDS YP_248029.1 68248917 3429750 411201..412094 1 NC_007146.2 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 412094 xerD 3429750 xerD Haemophilus influenzae 86-028NP site-specific tyrosine recombinase XerD YP_248029.1 411201 D 281310 CDS YP_248030.1 68248918 3429751 412267..412554 1 NC_007146.2 Similar to: HI0310, Y310_HAEIN; hypothetical protein 412554 3429751 NTHI0429 Haemophilus influenzae 86-028NP hypothetical protein YP_248030.1 412267 D 281310 CDS YP_248031.1 68248919 3429752 complement(412606..413613) 1 NC_007146.2 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 413613 ruvB 3429752 ruvB Haemophilus influenzae 86-028NP Holliday junction DNA helicase RuvB YP_248031.1 412606 R 281310 CDS YP_248032.1 68248920 3429753 complement(413621..414235) 1 NC_007146.2 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 414235 ruvA 3429753 ruvA Haemophilus influenzae 86-028NP Holliday junction DNA helicase RuvA YP_248032.1 413621 R 281310 CDS YP_248033.1 68248921 3429754 complement(414298..414870) 1 NC_007146.2 holliday junction nuclease RuvC; holliday juction resolvase RuvC; endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 414870 ruvC 3429754 ruvC Haemophilus influenzae 86-028NP Holliday junction resolvase YP_248033.1 414298 R 281310 CDS YP_248034.1 68248922 3429755 complement(414917..415657) 1 NC_007146.2 Similar to: HI0315, Y315_HAEIN; hypothetical protein 415657 3429755 NTHI0433 Haemophilus influenzae 86-028NP hypothetical protein YP_248034.1 414917 R 281310 CDS YP_248035.1 68248923 3429756 complement(415669..416142) 1 NC_007146.2 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 416142 ntpA 3429756 ntpA Haemophilus influenzae 86-028NP dATP pyrophosphohydrolase YP_248035.1 415669 R 281310 CDS YP_248036.1 68248924 3429757 complement(416164..417930) 1 NC_007146.2 aspartate--tRNA ligase; AspRS; catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 417930 aspS 3429757 aspS Haemophilus influenzae 86-028NP aspartyl-tRNA synthetase YP_248036.1 416164 R 281310 CDS YP_248037.1 68248925 3429758 418149..418667 1 NC_007146.2 Similar to: HI0318, Y318_HAEIN; hypothetical protein 418667 3429758 NTHI0436 Haemophilus influenzae 86-028NP hypothetical protein YP_248037.1 418149 D 281310 CDS YP_248038.1 68248926 3429759 418720..419445 1 NC_007146.2 fold typical of S-adenosyl-L-methionine-dependent methyltransferases; Similar to: HI0319, YECO_HAEIN; hypothetical protein 419445 3429759 NTHI0438 Haemophilus influenzae 86-028NP hypothetical protein YP_248038.1 418720 D 281310 CDS YP_248039.1 68248927 3429760 419538..419774 1 NC_007146.2 Similar to: HI0321, Y321_HAEIN; hypothetical protein 419774 3429760 NTHI0439 Haemophilus influenzae 86-028NP hypothetical protein YP_248039.1 419538 D 281310 CDS YP_248040.1 68248928 3429761 419771..420175 1 NC_007146.2 Similar to: HI0322, Y322_HAEIN; nucleic acid-binding protein 420175 3429761 NTHI0440 Haemophilus influenzae 86-028NP nucleic acid-binding protein YP_248040.1 419771 D 281310 CDS YP_248041.1 68248929 3429762 420242..420649 1 NC_007146.2 methylglyoxalase; aldoketomutase; glyoxalase I; Glx I; Ketone-aldehyde mutase; S-D-lactoylglutathione methylglyoxal lyase; Similar to: HI0323, LGUL_HAEIN; lactoylglutathione lyase 420649 gloA 3429762 gloA Haemophilus influenzae 86-028NP lactoylglutathione lyase YP_248041.1 420242 D 281310 CDS YP_248042.1 68248930 3429763 420723..421412 1 NC_007146.2 exoribonuclease T; RNase T; Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 421412 rnt 3429763 rnt Haemophilus influenzae 86-028NP ribonuclease T YP_248042.1 420723 D 281310 CDS YP_248043.1 68248931 3429764 421726..423078 1 NC_007146.2 Similar to: HI0325, Y325_HAEIN; hypothetical protein 423078 3429764 NTHI0443 Haemophilus influenzae 86-028NP hypothetical protein YP_248043.1 421726 D 281310 CDS YP_248044.1 68248932 3429765 423111..423698 1 NC_007146.2 Similar to: HI0326, Y326_HAEIN; primosomal replication protein N 423698 3429765 NTHI0444 Haemophilus influenzae 86-028NP primosomal replication protein N YP_248044.1 423111 D 281310 CDS YP_248045.1 68248933 3429767 complement(424049..424615) 1 NC_007146.2 EF-P; Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 424615 efp 3429767 efp Haemophilus influenzae 86-028NP elongation factor P YP_248045.1 424049 R 281310 CDS YP_248046.1 68248934 3429768 424653..425669 1 NC_007146.2 Similar to: HI0329, YJEK_HAEIN; lysine 2,3-aminomutase 425669 3429768 NTHI0447 Haemophilus influenzae 86-028NP lysine 2,3-aminomutase YP_248046.1 424653 D 281310 CDS YP_248047.1 68248935 3429769 425768..427063 1 NC_007146.2 Similar to: HI0330, OAPA_HAEIN; opacity associated protein 427063 oapA 3429769 oapA Haemophilus influenzae 86-028NP opacity associated protein YP_248047.1 425768 D 281310 CDS YP_248048.1 68248936 3429770 427122..427526 1 NC_007146.2 Similar to: HI0331, OAPB_HAEIN; opacity associated protein OapB 427526 oapB 3429770 oapB Haemophilus influenzae 86-028NP opacity associated protein OapB YP_248048.1 427122 D 281310 CDS YP_248049.1 68248937 3429771 427529..428239 1 NC_007146.2 recombination protein O; involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 428239 recO 3429771 recO Haemophilus influenzae 86-028NP DNA repair protein RecO YP_248049.1 427529 D 281310 CDS YP_248050.1 68248938 3429772 428239..429555 1 NC_007146.2 23S rRNA(M-5-U1939)-methyltransferase; in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 429555 rumA 3429772 rumA Haemophilus influenzae 86-028NP 23S rRNA 5-methyluridine methyltransferase YP_248050.1 428239 D 281310 CDS YP_248051.1 68248939 3429773 429633..431864 1 NC_007146.2 ATP:GTP 3'-pyrophosphotransferase; ppGpp synthetase I; (P)ppGpp synthetase; Similar to: HI0334, RELA_HAEIN; GTP pyrophosphokinase 431864 relA 3429773 relA Haemophilus influenzae 86-028NP GTP pyrophosphokinase YP_248051.1 429633 D 281310 CDS YP_248052.1 68248940 3429774 431879..432235 1 NC_007146.2 DAGK; diglyceride kinase; DGK; Similar to: HI0335, KDGL_HAEIN; diacylglycerol kinase 432235 dgkA 3429774 dgkA Haemophilus influenzae 86-028NP diacylglycerol kinase YP_248052.1 431879 D 281310 CDS YP_248053.1 68248941 3429775 432318..432911 1 NC_007146.2 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 432911 mogA 3429775 mogA Haemophilus influenzae 86-028NP molybdenum cofactor biosynthesis protein MogA YP_248053.1 432318 D 281310 CDS YP_248054.1 68248942 3429776 432913..433251 1 NC_007146.2 Similar to: HI0337, GLNB_HAEIN; nitrogen regulatory protein P-II 433251 glnB 3429776 glnB Haemophilus influenzae 86-028NP nitrogen regulatory protein P-II YP_248054.1 432913 D 281310 CDS YP_248055.1 68248943 3429777 433251..434297 1 NC_007146.2 Similar to: HI0338, YHHT_HAEIN; hypothetical protein 434297 3429777 NTHI0457 Haemophilus influenzae 86-028NP hypothetical protein YP_248055.1 433251 D 281310 CDS YP_248056.1 68248944 3429778 complement(434339..436531) 1 NC_007146.2 replication factor Y; binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 436531 priA 3429778 priA Haemophilus influenzae 86-028NP primosome assembly protein PriA YP_248056.1 434339 R 281310 CDS YP_248057.1 68248945 3429779 436616..437356 1 NC_007146.2 tRNA(m7G46)-methyltransferase; tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 437356 trmB 3429779 trmB Haemophilus influenzae 86-028NP tRNA (guanine-N(7)-)-methyltransferase YP_248057.1 436616 D 281310 CDS YP_248058.1 68248946 3429780 437441..437785 1 NC_007146.2 Similar to: HI0341, YGGL_HAEIN; hypothetical protein 437785 3429780 NTHI0460 Haemophilus influenzae 86-028NP hypothetical protein YP_248058.1 437441 D 281310 CDS YP_248059.1 68248947 3429781 437991..438521 1 NC_007146.2 Similar to: HI0342, NAPF_HAEIN; ferredoxin-type protein NapF 438521 napF 3429781 napF Haemophilus influenzae 86-028NP ferredoxin-type protein NapF YP_248059.1 437991 D 281310 CDS YP_248060.1 68248948 3429782 438514..438795 1 NC_007146.2 Similar to: HI0343, NAPD_HAEIN; NapD 438795 napD 3429782 napD Haemophilus influenzae 86-028NP NapD YP_248060.1 438514 D 281310 CDS YP_248061.1 68248949 3429783 438817..441315 1 NC_007146.2 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 441315 napA 3429783 napA Haemophilus influenzae 86-028NP nitrate reductase catalytic subunit YP_248061.1 438817 D 281310 CDS YP_248062.1 68248950 3429784 441369..442208 1 NC_007146.2 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 442208 napG 3429784 napG Haemophilus influenzae 86-028NP quinol dehydrogenase periplasmic component YP_248062.1 441369 D 281310 CDS YP_248063.1 68248951 3429785 442208..443071 1 NC_007146.2 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 443071 napH 3429785 napH Haemophilus influenzae 86-028NP quinol dehydrogenase membrane component YP_248063.1 442208 D 281310 CDS YP_248064.1 68248952 3429786 443068..443520 1 NC_007146.2 Similar to: HI0347, NAPB_HAEIN; diheme cytochrome C NapB 443520 napB 3429786 napB Haemophilus influenzae 86-028NP diheme cytochrome C NapB YP_248064.1 443068 D 281310 CDS YP_248065.1 68248953 3429787 443535..444137 1 NC_007146.2 Similar to: HI0348, NAPC_HAEIN; cytochrome C-type protein NapC 444137 napC 3429787 napC Haemophilus influenzae 86-028NP cytochrome C-type protein NapC YP_248065.1 443535 D 281310 CDS YP_248066.1 68248954 3429788 complement(444297..444941) 1 NC_007146.2 ATP-AMP transphosphorylase; essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 444941 adk 3429788 adk Haemophilus influenzae 86-028NP adenylate kinase YP_248066.1 444297 R 281310 CDS YP_248067.1 68248955 3429789 complement(445026..446303) 1 NC_007146.2 Similar to: HI0350, Y350_HAEIN; integral membrane signal transducer protein 446303 lic3C 3429789 lic3C Haemophilus influenzae 86-028NP integral membrane signal transducer protein YP_248067.1 445026 R 281310 CDS YP_248068.1 68248956 3429790 complement(446445..447461) 1 NC_007146.2 galactowaldenase; UDP-galactose 4-epimerase; Similar to: HI0351, GALE_HAEIN; UDP-glucose 4-epimerase 447461 galE 3429790 galE Haemophilus influenzae 86-028NP UDP-glucose 4-epimerase YP_248068.1 446445 R 281310 CDS YP_248069.1 68248957 3429791 complement(447634..448596) 1 NC_007146.2 Similar to: HI0352, Y352_HAEIN; CMP-Neu5Ac--lipooligosaccharide alpha 2-3 sialyltransferase 448596 lic3A 3429791 lic3A Haemophilus influenzae 86-028NP CMP-Neu5Ac--lipooligosaccharide alpha 2-3 sialyltransferase YP_248069.1 447634 R 281310 CDS YP_248070.1 68248958 3429792 448995..449717 1 NC_007146.2 Similar to: HI0354, Y354_HAEIN; ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase 449717 3429792 NTHI0473 Haemophilus influenzae 86-028NP ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase YP_248070.1 448995 D 281310 CDS YP_248071.1 68248959 3429793 449714..450451 1 NC_007146.2 Similar to: HI0355, Y355_HAEIN; ABC-type nitrate/sulfonate/bicarbonate transport system, permease 450451 3429793 NTHI0474 Haemophilus influenzae 86-028NP ABC-type nitrate/sulfonate/bicarbonate transport system, permease YP_248071.1 449714 D 281310 CDS YP_248072.1 68248960 3429794 450473..451417 1 NC_007146.2 Similar to: HI0357, Y357_HAEIN; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic component 451417 3429794 NTHI0475 Haemophilus influenzae 86-028NP ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic component YP_248072.1 450473 D 281310 CDS YP_248073.1 68248961 3429795 451427..452074 1 NC_007146.2 Similar to: HI0358, Y358_HAEIN; transcription activator 452074 3429795 NTHI0476 Haemophilus influenzae 86-028NP transcription activator YP_248073.1 451427 D 281310 CDS YP_248074.1 68248962 3429796 complement(452169..452984) 1 NC_007146.2 Similar to: HI0359, Y359_HAEIN; ABC-type chelated iron transport system, permease 452984 hfeD 3429796 hfeD Haemophilus influenzae 86-028NP ABC-type chelated iron transport system, permease YP_248074.1 452169 R 281310 CDS YP_248075.1 68248963 3429797 complement(452977..453825) 1 NC_007146.2 Similar to: HI0360, Y360_HAEIN; ABC-type chelated iron transport system, permease 453825 hfeC 3429797 hfeC Haemophilus influenzae 86-028NP ABC-type chelated iron transport system, permease YP_248075.1 452977 R 281310 CDS YP_248076.1 68248964 3429798 complement(453829..454749) 1 NC_007146.2 Similar to: HI0361, Y361_HAEIN; ABC-type chelated iron transport system, ATPase 454749 hfeB 3429798 hfeB Haemophilus influenzae 86-028NP ABC-type chelated iron transport system, ATPase YP_248076.1 453829 R 281310 CDS YP_248077.1 68248965 3429799 complement(454749..455630) 1 NC_007146.2 Similar to: HI0362, Y362_HAEIN; periplasmic chelated iron binding protein 455630 hfeA 3429799 hfeA Haemophilus influenzae 86-028NP periplasmic chelated iron binding protein YP_248077.1 454749 R 281310 CDS YP_248078.1 68248966 3429800 455936..456400 1 NC_007146.2 hypothetical protein 456400 3429800 NTHI0482 Haemophilus influenzae 86-028NP hypothetical protein YP_248078.1 455936 D 281310 CDS YP_248079.1 68248967 3429801 complement(456492..457370) 1 NC_007146.2 PBP-7; D-alanyl-D-alanine-endopeptidase; DD-endopeptidase; Similar to: HI0364, PBP7_HAEIN; penicillin-binding protein 7-like protein 457370 pbpG 3429801 pbpG Haemophilus influenzae 86-028NP penicillin-binding protein 7-like protein YP_248079.1 456492 R 281310 CDS YP_248080.1 68248968 3429802 457595..458767 1 NC_007146.2 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 458767 3429802 NTHI0485 Haemophilus influenzae 86-028NP ribosomal RNA large subunit methyltransferase N YP_248080.1 457595 D 281310 CDS YP_248081.1 68248969 3429803 458867..459406 1 NC_007146.2 Similar to: HI0366, Y366_HAEIN; hypothetical protein 459406 3429803 NTHI0486 Haemophilus influenzae 86-028NP hypothetical protein YP_248081.1 458867 D 281310 CDS YP_248082.1 68248970 3429804 459478..460389 1 NC_007146.2 Similar to: HI0367, Y367_HAEIN; hypothetical protein 460389 3429804 NTHI0487 Haemophilus influenzae 86-028NP hypothetical protein YP_248082.1 459478 D 281310 CDS YP_248083.1 68248971 3429805 460398..461504 1 NC_007146.2 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 461504 ispG 3429805 ispG Haemophilus influenzae 86-028NP 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_248083.1 460398 D 281310 CDS YP_248084.1 68248972 3429806 461514..462785 1 NC_007146.2 histidine--tRNA ligase; HisRS; catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 462785 hisS 3429806 hisS Haemophilus influenzae 86-028NP histidyl-tRNA synthetase YP_248084.1 461514 D 281310 CDS YP_248085.1 68248973 3429807 462803..463417 1 NC_007146.2 Similar to: HI0370, Y370_HAEIN; hypothetical protein 463417 3429807 NTHI0490 Haemophilus influenzae 86-028NP hypothetical protein YP_248085.1 462803 D 281310 CDS YP_248086.1 68248974 3429808 complement(463468..463662) 1 NC_007146.2 Similar to: HI0371, YFHJ_HAEIN; hypothetical protein 463662 3429808 NTHI0491 Haemophilus influenzae 86-028NP hypothetical protein YP_248086.1 463468 R 281310 CDS YP_248087.1 68248975 3429809 complement(463662..464003) 1 NC_007146.2 Similar to: HI0372, FER_HAEIN; (2Fe-2S) ferredoxin 464003 fdx 3429809 fdx Haemophilus influenzae 86-028NP (2Fe-2S) ferredoxin YP_248087.1 463662 R 281310 CDS YP_248088.1 68248976 3429810 complement(464043..465902) 1 NC_007146.2 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 465902 hscA 3429810 hscA Haemophilus influenzae 86-028NP chaperone protein HscA YP_248088.1 464043 R 281310 CDS YP_248089.1 68248977 3429811 complement(465921..466607) 1 NC_007146.2 Similar to: HI0374, YBFG_HAEIN; hypothetical protein 466607 3429811 NTHI0494 Haemophilus influenzae 86-028NP hypothetical protein YP_248089.1 465921 R 281310 CDS YP_248090.1 68248978 3429812 complement(466658..467182) 1 NC_007146.2 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 467182 hscB 3429812 hscB Haemophilus influenzae 86-028NP co-chaperone HscB YP_248090.1 466658 R 281310 CDS YP_248091.1 68248979 3429813 complement(467195..467518) 1 NC_007146.2 Similar to: HI0376, YFHF_HAEIN; hypothetical protein 467518 3429813 NTHI0496 Haemophilus influenzae 86-028NP hypothetical protein YP_248091.1 467195 R 281310 CDS YP_248092.1 68248980 3429814 complement(467576..467956) 1 NC_007146.2 Similar to: HI0377, NIFU_HAEIN; scaffold protein 467956 nifU 3429814 nifU Haemophilus influenzae 86-028NP scaffold protein YP_248092.1 467576 R 281310 CDS YP_248093.1 68248981 3429815 complement(468016..469236) 1 NC_007146.2 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 469236 nifS2 3429815 nifS2 Haemophilus influenzae 86-028NP cysteine desulfurase YP_248093.1 468016 R 281310 CDS YP_248094.1 68248982 3429816 complement(469297..469749) 1 NC_007146.2 Similar to: HI0379, YFHP_HAEIN; hypothetical protein 469749 3429816 NTHI0499 Haemophilus influenzae 86-028NP hypothetical protein YP_248094.1 469297 R 281310 CDS YP_248095.1 68248983 3429817 complement(469802..470527) 1 NC_007146.2 Similar to: HI0380, YFHQ_HAEIN; tRNA/rRNA methyltransferase 470527 3429817 NTHI0500 Haemophilus influenzae 86-028NP tRNA/rRNA methyltransferase YP_248095.1 469802 R 281310 CDS YP_248096.1 68248984 3429820 complement(470967..471428) 1 NC_007146.2 OMP P6; 15 kDa peptidoglycan-associated lipoprotein; PC protein; Similar to: HI0381, PAL_HAEIN; outer membrane protein P6 471428 pal 3429820 pal Haemophilus influenzae 86-028NP outer membrane protein P6 YP_248096.1 470967 R 281310 CDS YP_248097.1 68248985 3429821 complement(471452..472735) 1 NC_007146.2 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 472735 tolB 3429821 tolB Haemophilus influenzae 86-028NP translocation protein TolB YP_248097.1 471452 R 281310 CDS YP_248098.1 68248986 3429822 complement(472777..474003) 1 NC_007146.2 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 474003 tolA 3429822 tolA Haemophilus influenzae 86-028NP cell envelope integrity inner membrane protein TolA YP_248098.1 472777 R 281310 CDS YP_248099.1 68248987 3429823 complement(474019..474438) 1 NC_007146.2 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 474438 tolR 3429823 tolR Haemophilus influenzae 86-028NP colicin uptake protein TolR YP_248099.1 474019 R 281310 CDS YP_248100.1 68248988 3429824 complement(474509..475195) 1 NC_007146.2 Similar to: HI0385, TOLQ_HAEIN; hypothetical protein 475195 tolQ 3429824 tolQ Haemophilus influenzae 86-028NP hypothetical protein YP_248100.1 474509 R 281310 CDS YP_248101.1 68248989 3429825 complement(475212..475622) 1 NC_007146.2 Similar to: HI0386, YBGC_HAEIN; thioesterase 475622 3429825 NTHI0506 Haemophilus influenzae 86-028NP thioesterase YP_248101.1 475212 R 281310 CDS YP_248102.1 68248990 3429826 475947..477869 1 NC_007146.2 Similar to: HI0387, YOAA_HAEIN; ATP-dependent helicase 477869 dinG 3429826 dinG Haemophilus influenzae 86-028NP ATP-dependent helicase YP_248102.1 475947 D 281310 CDS YP_248103.1 68248991 3429827 477882..478592 1 NC_007146.2 Similar to: HI0388, YEAZ_HAEIN; hypothetical protein 478592 3429827 NTHI0508 Haemophilus influenzae 86-028NP hypothetical protein YP_248103.1 477882 D 281310 CDS YP_248104.1 68248992 3429828 478617..479168 1 NC_007146.2 Similar to: HI0389, Y389_HAEIN; starvation-inducible outer membrane lipoprotein 479168 3429828 NTHI0509 Haemophilus influenzae 86-028NP starvation-inducible outer membrane lipoprotein YP_248104.1 478617 D 281310 CDS YP_248105.1 68248993 3429829 479210..480898 1 NC_007146.2 long-chain acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 480898 lcfA 3429829 lcfA Haemophilus influenzae 86-028NP long-chain-fatty-acid--CoA ligase YP_248105.1 479210 D 281310 CDS YP_248106.1 68248994 3429830 480954..482096 1 NC_007146.2 RNase D; Similar to: HI0390, RND_HAEIN; ribonuclease D 482096 rnd 3429830 rnd Haemophilus influenzae 86-028NP ribonuclease D YP_248106.1 480954 D 281310 CDS YP_248107.1 68248995 3429831 complement(482139..484007) 1 NC_007146.2 Similar to: HI0392, Y392_HAEIN; acyltransferase 484007 3429831 NTHI0512 Haemophilus influenzae 86-028NP acyltransferase YP_248107.1 482139 R 281310 CDS YP_248108.1 68248996 3429832 complement(484081..485172) 1 NC_007146.2 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 485172 3429832 NTHI0513 Haemophilus influenzae 86-028NP GTP-dependent nucleic acid-binding protein EngD YP_248108.1 484081 R 281310 CDS YP_248109.1 68248997 3429833 complement(485220..485804) 1 NC_007146.2 PTH; Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 485804 pth 3429833 pth Haemophilus influenzae 86-028NP peptidyl-tRNA hydrolase YP_248109.1 485220 R 281310 CDS YP_248110.1 68248998 3429834 485987..486295 1 NC_007146.2 Similar to: HI0395, YFJF_HAEIN; hypothetical protein 486295 3429834 NTHI0516 Haemophilus influenzae 86-028NP hypothetical protein YP_248110.1 485987 D 281310 CDS YP_248111.1 68248999 3429835 486298..487512 1 NC_007146.2 Similar to: HI0396, YCFD_HAEIN; hypothetical protein 487512 3429835 NTHI0517 Haemophilus influenzae 86-028NP hypothetical protein YP_248111.1 486298 D 281310 CDS YP_248112.1 68249000 3429836 487514..488833 1 NC_007146.2 exonuclease VII large subunit; bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 488833 xseA 3429836 xseA Haemophilus influenzae 86-028NP exodeoxyribonuclease VII large subunit YP_248112.1 487514 D 281310 CDS YP_248113.1 68249001 3429837 489010..489663 1 NC_007146.2 ADP-ribose diphosphatase; adenosine diphosphoribose pyrophosphatase; ADPR-PPase; ADP-ribose phosphohydrolase; Similar to: HI0398, ADPP_HAEIN; ADP-ribose pyrophosphatase 489663 adpP 3429837 adpP Haemophilus influenzae 86-028NP ADP-ribose pyrophosphatase YP_248113.1 489010 D 281310 CDS YP_248114.1 68249002 3429838 489673..490497 1 NC_007146.2 Similar to: HI0399, ICC_HAEIN; cyclic 3',5'-adenosine monophosphate phosphodiesterase 490497 icc 3429838 icc Haemophilus influenzae 86-028NP cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_248114.1 489673 D 281310 CDS YP_248115.1 68249003 3429839 complement(490595..490882) 1 NC_007146.2 Similar to: HI0400, Y400_HAEIN; hypothetical protein 490882 3429839 NTHI0521 Haemophilus influenzae 86-028NP hypothetical protein YP_248115.1 490595 R 281310 CDS YP_248116.1 68249004 3429840 491079..492455 1 NC_007146.2 OMP P1; Similar to: HI0401, OM12_HAEIN; long-chain fatty acid ABC transporter 492455 ompP1 3429840 ompP1 Haemophilus influenzae 86-028NP long-chain fatty acid ABC transporter YP_248116.1 491079 D 281310 CDS YP_248117.1 68249005 3429841 492501..493070 1 NC_007146.2 6-O-methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase; Similar to: HI0402, OGT_HAEIN; methylated-DNA--protein-cysteine methyltransferase 493070 ogt 3429841 ogt Haemophilus influenzae 86-028NP methylated-DNA--protein-cysteine methyltransferase YP_248117.1 492501 D 281310 CDS YP_248118.1 68249006 3429842 493067..493738 1 NC_007146.2 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 493738 mutH 3429842 mutH Haemophilus influenzae 86-028NP DNA mismatch repair protein YP_248118.1 493067 D 281310 CDS YP_248119.1 68249007 3429843 complement(493746..495038) 1 NC_007146.2 Similar to: HI0404, MESJ_HAEIN; cell cycle protein MesJ 495038 mesJ 3429843 mesJ Haemophilus influenzae 86-028NP cell cycle protein MesJ YP_248119.1 493746 R 281310 CDS YP_248120.1 68249008 3429845 complement(495215..496162) 1 NC_007146.2 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 496162 accA 3429845 accA Haemophilus influenzae 86-028NP acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_248120.1 495215 R 281310 CDS YP_248121.1 68249009 3429846 complement(496251..497036) 1 NC_007146.2 Similar to: HI0407, ZNUB_HAEIN; high-affinity zinc uptake system membrane protein ZnuB 497036 znuB 3429846 znuB Haemophilus influenzae 86-028NP high-affinity zinc uptake system membrane protein ZnuB YP_248121.1 496251 R 281310 CDS YP_248122.1 68249010 3429847 complement(497036..497842) 1 NC_007146.2 Similar to: HI0408, ZNUC_HAEIN; ABC transporter ATP-binding protein 497842 znuC 3429847 znuC Haemophilus influenzae 86-028NP ABC transporter ATP-binding protein YP_248122.1 497036 R 281310 CDS YP_248123.1 68249011 3429848 498014..499441 1 NC_007146.2 Similar to: HI0409, Y409_HAEIN; metalloprotease 499441 3429848 NTHI0532 Haemophilus influenzae 86-028NP metalloprotease YP_248123.1 498014 D 281310 CDS YP_248124.1 68249012 3429849 499556..500512 1 NC_007146.2 Similar to: HI0410, TYRR_HAEIN; transcriptional regulatory protein TyrR 500512 tyrR 3429849 tyrR Haemophilus influenzae 86-028NP transcriptional regulatory protein TyrR YP_248124.1 499556 D 281310 CDS YP_248125.1 68249013 3429850 complement(500608..500883) 1 NC_007146.2 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 500883 hfq 3429850 hfq Haemophilus influenzae 86-028NP RNA-binding protein Hfq YP_248125.1 500608 R 281310 CDS YP_248126.1 68249014 3429851 complement(500974..501969) 1 NC_007146.2 pseudouridylate synthase; Uracil hydrolyase; catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 501969 rluC 3429851 rluC Haemophilus influenzae 86-028NP 23S rRNA pseudouridylate synthase C YP_248126.1 500974 R 281310 CDS YP_248127.1 68249015 3429852 502315..505170 1 NC_007146.2 RNase E; Similar to: HI0413, RNE_HAEIN; ribonuclease E 505170 rne 3429852 rne Haemophilus influenzae 86-028NP ribonuclease E YP_248127.1 502315 D 281310 CDS YP_248128.1 68249016 3429853 505402..505614 1 NC_007146.2 Similar to: HI0414, Y414_HAEIN; hypothetical protein 505614 3429853 NTHI0539 Haemophilus influenzae 86-028NP hypothetical protein YP_248128.1 505402 D 281310 CDS YP_248129.1 68249017 3429854 505938..506735 1 NC_007146.2 4-methyl-5-beta-hydroxyethylthiazole kinase; Thz kinase; TH kinase; catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 506735 thiM 3429854 thiM Haemophilus influenzae 86-028NP hydroxyethylthiazole kinase YP_248129.1 505938 D 281310 CDS YP_248130.1 68249018 3429855 506728..507537 1 NC_007146.2 HMP-phosphate kinase; HMP-P kinase; catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 507537 thiD 3429855 thiD Haemophilus influenzae 86-028NP phosphomethylpyrimidine kinase YP_248130.1 506728 D 281310 CDS YP_248131.1 68249019 3429856 507548..508228 1 NC_007146.2 TMP pyrophosphorylase; TMP-PPase; thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 508228 thiE 3429856 thiE Haemophilus influenzae 86-028NP thiamine-phosphate pyrophosphorylase YP_248131.1 507548 D 281310 CDS YP_248132.1 68249020 3429857 508212..509516 1 NC_007146.2 Similar to: HI0418, Y418_HAEIN; metabolite transporter 509516 3429857 NTHI0543 Haemophilus influenzae 86-028NP metabolite transporter YP_248132.1 508212 D 281310 CDS YP_248133.1 68249021 3429858 complement(509528..509629) 1 NC_007146.2 hypothetical protein 509629 3429858 NTHI0544 Haemophilus influenzae 86-028NP hypothetical protein YP_248133.1 509528 R 281310 CDS YP_248134.1 68249022 3429859 509685..511064 1 NC_007146.2 Similar to: HI0419, YEGQ_HAEIN; protease 511064 3429859 NTHI0545 Haemophilus influenzae 86-028NP protease YP_248134.1 509685 D 281310 CDS YP_248135.1 68249023 3429860 complement(511098..512417) 1 NC_007146.2 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 512417 srmB 3429860 srmB Haemophilus influenzae 86-028NP ATP-dependent RNA helicase SrmB YP_248135.1 511098 R 281310 CDS YP_248136.1 68249024 3429861 512463..513185 1 NC_007146.2 Similar to: HI0423, YFIC_HAEIN; O-methyltransferase 513185 3429861 NTHI0547 Haemophilus influenzae 86-028NP O-methyltransferase YP_248136.1 512463 D 281310 CDS YP_248137.1 68249025 3429863 513968..515335 1 NC_007146.2 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 515335 pssA 3429863 pssA Haemophilus influenzae 86-028NP phosphatidylserine synthase YP_248137.1 513968 D 281310 CDS YP_248138.1 68249026 3429864 complement(515381..516106) 1 NC_007146.2 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 516106 fadR 3429864 fadR Haemophilus influenzae 86-028NP fatty acid metabolism regulator YP_248138.1 515381 R 281310 CDS YP_248139.1 68249027 3429865 516207..517775 1 NC_007146.2 Sodium/proton antiporter 2; involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 517775 nhaB 3429865 nhaB Haemophilus influenzae 86-028NP sodium/proton antiporter YP_248139.1 516207 D 281310 CDS YP_248140.1 68249028 3429866 517785..518318 1 NC_007146.2 disulfide oxidoreductase; disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 518318 dsbB 3429866 dsbB Haemophilus influenzae 86-028NP disulfide bond formation protein B YP_248140.1 517785 D 281310 CDS YP_248141.1 68249029 3429867 complement(518373..520205) 1 NC_007146.2 hexosephosphate aminotransferase; D-fructose-6-phosphate amidotransferase; GFAT; L-glutamine-D-fructose-6-phosphate amidotransferase; glucosamine-6-phosphate synthase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 520205 glmS 3429867 glmS Haemophilus influenzae 86-028NP glucosamine--fructose-6-phosphate aminotransferase YP_248141.1 518373 R 281310 CDS YP_248142.1 68249030 3429868 complement(520318..520728) 1 NC_007146.2 Similar to: HI0430, DBH_HAEIN; DNA-binding protein HU 520728 hupA 3429868 hupA Haemophilus influenzae 86-028NP DNA-binding protein HU YP_248142.1 520318 R 281310 CDS YP_248143.1 68249031 3429869 complement(520730..521320) 1 NC_007146.2 Similar to: HI0431, YJAG_HAEIN; hypothetical protein 521320 3429869 NTHI0555 Haemophilus influenzae 86-028NP hypothetical protein YP_248143.1 520730 R 281310 CDS YP_248144.1 68249032 3429870 complement(521356..522150) 1 NC_007146.2 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 522150 nudC 3429870 nudC Haemophilus influenzae 86-028NP NADH pyrophosphatase YP_248144.1 521356 R 281310 CDS YP_248145.1 68249033 3429871 complement(522217..522813) 1 NC_007146.2 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 522813 orfG 3429871 orfG Haemophilus influenzae 86-028NP DNA uptake protein YP_248145.1 522217 R 281310 CDS YP_248146.1 68249034 3429872 complement(522889..523575) 1 NC_007146.2 DNA transformation protein comF; protein COM101A; Similar to: HI0434, COMF_HAEIN; competence protein F 523575 comF 3429872 comF Haemophilus influenzae 86-028NP competence protein F YP_248146.1 522889 R 281310 CDS YP_248147.1 68249035 3429873 complement(523588..524925) 1 NC_007146.2 DNA transformation protein comE; Similar to: HI0435, COME_HAEIN; competence protein E 524925 comE 3429873 comE Haemophilus influenzae 86-028NP competence protein E YP_248147.1 523588 R 281310 CDS YP_248148.1 68249036 3429874 complement(524935..525348) 1 NC_007146.2 DNA transformation protein comD; Similar to: HI0436, COMD_HAEIN; competence protein D 525348 comD 3429874 comD Haemophilus influenzae 86-028NP competence protein D YP_248148.1 524935 R 281310 CDS YP_248149.1 68249037 3429875 complement(525345..525866) 1 NC_007146.2 DNA transformation protein comC; Similar to: HI0437, COMC_HAEIN; competence protein C 525866 comC 3429875 comC Haemophilus influenzae 86-028NP competence protein C YP_248149.1 525345 R 281310 CDS YP_248150.1 68249038 3429876 complement(525863..526369) 1 NC_007146.2 DNA transformation protein comB; Similar to: HI0438, COMB_HAEIN; competence protein B 526369 comB 3429876 comB Haemophilus influenzae 86-028NP competence protein B YP_248150.1 525863 R 281310 CDS YP_248151.1 68249039 3429877 complement(526370..527167) 1 NC_007146.2 DNA transformation protein comA; Similar to: HI0439, COMA_HAEIN; competence protein A 527167 comA 3429877 comA Haemophilus influenzae 86-028NP competence protein A YP_248151.1 526370 R 281310 CDS YP_248152.1 68249040 3429878 527266..529860 1 NC_007146.2 PBP-1a; PBP1a; penicillin-binding protein A; peptidoglycan TGase; DD-transpeptidase; Similar to: HI0440, PBPA_HAEIN; penicillin-binding protein 1A 529860 mrcA 3429878 mrcA Haemophilus influenzae 86-028NP penicillin-binding protein 1A YP_248152.1 527266 D 281310 CDS YP_248153.1 68249041 3429879 529933..530778 1 NC_007146.2 Similar to: HI0441, YHIR_HAEIN; hypothetical protein 530778 3429879 NTHI0568 Haemophilus influenzae 86-028NP hypothetical protein YP_248153.1 529933 D 281310 CDS YP_248154.1 68249042 3429880 530911..531276 1 NC_007146.2 Similar to: HI0442, Y442_HAEIN; hypothetical protein 531276 3429880 NTHI0569 Haemophilus influenzae 86-028NP hypothetical protein YP_248154.1 530911 D 281310 CDS YP_248155.1 68249043 3429881 531407..532009 1 NC_007146.2 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 532009 recR 3429881 recR Haemophilus influenzae 86-028NP recombination protein RecR YP_248155.1 531407 D 281310 CDS YP_248156.1 68249044 3429882 532025..533980 1 NC_007146.2 decatenates replicating daughter chromosomes; DNA topoisomerase III 533980 topB 3429882 topB Haemophilus influenzae 86-028NP DNA topoisomerase III YP_248156.1 532025 D 281310 CDS YP_248157.1 68249045 3429883 534089..534430 1 NC_007146.2 Similar to: HI0445, SECG_HAEIN; preprotein translocase subunit SecG 534430 secG 3429883 secG Haemophilus influenzae 86-028NP preprotein translocase subunit SecG YP_248157.1 534089 D 281310 CDS YP_248158.1 68249046 3429885 complement(534975..536645) 1 NC_007146.2 EIIBC-Fru; fructose-permease IIBC component; phosphotransferase enzyme II, BC component; EII-Fru; Similar to: HI0446, PTFB_HAEIN; PTS system, fructose-specific IIBC component 536645 fruA 3429885 fruA Haemophilus influenzae 86-028NP PTS system, fructose-specific IIBC component YP_248158.1 534975 R 281310 CDS YP_248159.1 68249047 3429886 complement(536647..537588) 1 NC_007146.2 fructose 1-phosphate kinase; converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 537588 fruK 3429886 fruK Haemophilus influenzae 86-028NP 1-phosphofructokinase YP_248159.1 536647 R 281310 CDS YP_248160.1 68249048 3429887 complement(537590..539089) 1 NC_007146.2 EIIA-Fru; fructose-permease IIA/FPr component; phosphotransferase enzyme II, A/FPr component; phosphotransferase FPr protein; Pseudo-HPr; EIII-Fru; fructose PTS diphosphoryl transfer protein; phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein 539089 fruB 3429887 fruB Haemophilus influenzae 86-028NP bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein YP_248160.1 537590 R 281310 CDS YP_248161.1 68249049 3429888 complement(539161..539697) 1 NC_007146.2 Similar to: HI0449, Y449_HAEIN; hypothetical protein 539697 3429888 NTHI0576 Haemophilus influenzae 86-028NP hypothetical protein YP_248161.1 539161 R 281310 CDS YP_248162.1 68249050 3429889 complement(539784..540062) 1 NC_007146.2 Similar to: HI0450, VAPD_HAEIN; virulence-associated protein D 540062 vapD 3429889 vapD Haemophilus influenzae 86-028NP virulence-associated protein D YP_248162.1 539784 R 281310 CDS YP_248163.1 68249051 3429890 complement(540071..540262) 1 NC_007146.2 Similar to: HI0451, Y451_HAEIN; hypothetical protein 540262 vapX 3429890 vapX Haemophilus influenzae 86-028NP hypothetical protein YP_248163.1 540071 R 281310 CDS YP_248164.1 68249052 3429891 complement(540334..541632) 1 NC_007146.2 Similar to: HI0452, YTFL_HAEIN; hypothetical protein 541632 3429891 NTHI0579 Haemophilus influenzae 86-028NP hypothetical protein YP_248164.1 540334 R 281310 CDS YP_248165.1 68249053 3429892 complement(541683..542207) 1 NC_007146.2 Similar to: HI0453, Y453_HAEIN; hypothetical protein 542207 3429892 NTHI0580 Haemophilus influenzae 86-028NP hypothetical protein YP_248165.1 541683 R 281310 CDS YP_248166.1 68249054 3429893 complement(542234..543016) 1 NC_007146.2 Similar to: HI0454, YCFH_HAEIN; deoxyribonuclease 543016 3429893 NTHI0581 Haemophilus influenzae 86-028NP deoxyribonuclease YP_248166.1 542234 R 281310 CDS YP_248167.1 68249055 3429894 complement(543071..544054) 1 NC_007146.2 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 544054 holB 3429894 holB Haemophilus influenzae 86-028NP DNA polymerase III subunit delta' YP_248167.1 543071 R 281310 CDS YP_248168.1 68249056 3429895 complement(544051..544179) 1 NC_007146.2 hypothetical protein 544179 3429895 NTHI0584 Haemophilus influenzae 86-028NP hypothetical protein YP_248168.1 544051 R 281310 CDS YP_248169.1 68249057 3429896 544254..546377 1 NC_007146.2 Similar to: YDEU_ECOLI; autotransported protein Lav 546377 lav 3429896 lav Haemophilus influenzae 86-028NP autotransported protein Lav YP_248169.1 544254 D 281310 CDS YP_248170.1 68249058 3429897 complement(547283..547942) 1 NC_007146.2 dTMP kinase; catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 547942 tmk 3429897 tmk Haemophilus influenzae 86-028NP thymidylate kinase YP_248170.1 547283 R 281310 CDS YP_248171.1 68249059 3429898 complement(547932..548975) 1 NC_007146.2 Similar to: HI0457, YCEG_HAEIN; periplasmic solute-binding protein 548975 3429898 NTHI0587 Haemophilus influenzae 86-028NP periplasmic solute-binding protein YP_248171.1 547932 R 281310 CDS YP_248172.1 68249060 3429899 complement(549045..549986) 1 NC_007146.2 Similar to: HI0458, SURA_HAEIN; survival protein SurA-like protein 549986 surA 3429899 surA Haemophilus influenzae 86-028NP survival protein SurA-like protein YP_248172.1 549045 R 281310 CDS YP_248173.1 68249061 3429900 complement(550056..550595) 1 NC_007146.2 UPRTase; regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 550595 pyrR 3429900 pyrR Haemophilus influenzae 86-028NP bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_248173.1 550056 R 281310 CDS YP_248174.1 68249062 3429901 550727..551518 1 NC_007146.2 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 551518 mazG 3429901 mazG Haemophilus influenzae 86-028NP nucleoside triphosphate pyrophosphohydrolase YP_248174.1 550727 D 281310 CDS YP_248175.1 68249063 3429902 complement(551568..552443) 1 NC_007146.2 Similar to: HI0461, Y461_HAEIN; hypothetical protein 552443 3429902 NTHI0592 Haemophilus influenzae 86-028NP hypothetical protein YP_248175.1 551568 R 281310 CDS YP_248176.1 68249064 3429903 552636..555047 1 NC_007146.2 Lon protease; Similar to: HI0462, LON_HAEIN; ATP-dependent protease La 555047 lon 3429903 lon Haemophilus influenzae 86-028NP ATP-dependent protease La YP_248176.1 552636 D 281310 CDS YP_248177.1 68249065 3429904 555164..556315 1 NC_007146.2 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 556315 3429904 NTHI0594 Haemophilus influenzae 86-028NP coproporphyrinogen III oxidase YP_248177.1 555164 D 281310 CDS YP_248178.1 68249066 3429905 556449..557108 1 NC_007146.2 phosphoriboisomerase A; PRI; Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 557108 rpiA 3429905 rpiA Haemophilus influenzae 86-028NP ribose-5-phosphate isomerase A YP_248178.1 556449 D 281310 CDS YP_248179.1 68249067 3429906 557138..558370 1 NC_007146.2 PGDH; catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 558370 serA 3429906 serA Haemophilus influenzae 86-028NP D-3-phosphoglycerate dehydrogenase YP_248179.1 557138 D 281310 CDS YP_248180.1 68249068 3429907 complement(558413..559255) 1 NC_007146.2 Similar to: HI0466, Y466_HAEIN; glycine cleavage system protein T 559255 3429907 NTHI0597 Haemophilus influenzae 86-028NP glycine cleavage system protein T YP_248180.1 558413 R 281310 CDS YP_248181.1 68249069 3429908 complement(559265..560128) 1 NC_007146.2 Similar to: HI0467, YICC_HAEIN; hypothetical protein 560128 3429908 NTHI0598 Haemophilus influenzae 86-028NP hypothetical protein YP_248181.1 559265 R 281310 CDS YP_248182.1 68249070 3429909 560577..561488 1 NC_007146.2 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 561488 hisG 3429909 hisG Haemophilus influenzae 86-028NP ATP phosphoribosyltransferase YP_248182.1 560577 D 281310 CDS YP_248183.1 68249071 3429910 561581..562864 1 NC_007146.2 HDH; catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 562864 hisD 3429910 hisD Haemophilus influenzae 86-028NP histidinol dehydrogenase YP_248183.1 561581 D 281310 CDS YP_248184.1 68249072 3429911 562933..564036 1 NC_007146.2 imidazole acetol-phosphate transaminase 1; catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 564036 hisC 3429911 hisC Haemophilus influenzae 86-028NP histidinol-phosphate aminotransferase YP_248184.1 562933 D 281310 CDS YP_248185.1 68249073 3429912 564148..565236 1 NC_007146.2 IGPD; catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 565236 hisB 3429912 hisB Haemophilus influenzae 86-028NP imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_248185.1 564148 D 281310 CDS YP_248186.1 68249074 3429913 565302..565901 1 NC_007146.2 IGP synthase glutamine amidotransferase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 565901 hisH 3429913 hisH Haemophilus influenzae 86-028NP imidazole glycerol phosphate synthase subunit HisH YP_248186.1 565302 D 281310 CDS YP_248187.1 68249075 3429914 565937..566686 1 NC_007146.2 5-phosphoribosyl; 5-phosphoribosylamino; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 566686 hisA 3429914 hisA Haemophilus influenzae 86-028NP 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_248187.1 565937 D 281310 CDS YP_248188.1 68249076 3429915 566668..567444 1 NC_007146.2 IGP synthase cyclase subunit; IGP synthase subunit HisF; ImGP synthase subunit HisF; IGPS subunit HisF; catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 567444 hisF 3429915 hisF Haemophilus influenzae 86-028NP imidazole glycerol phosphate synthase subunit HisF YP_248188.1 566668 D 281310 CDS YP_248189.1 68249077 3429916 567444..568109 1 NC_007146.2 PRA-CH; PRA-PH; catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 568109 hisI 3429916 hisI Haemophilus influenzae 86-028NP bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein YP_248189.1 567444 D 281310 CDS YP_248190.1 68249078 3429917 568191..568343 1 NC_007146.2 hypothetical protein 568343 3429917 NTHI0606_1 Haemophilus influenzae 86-028NP hypothetical protein YP_248190.1 568191 D 281310 CDS YP_248191.1 68249079 3429918 568373..569575 1 NC_007146.2 TyrP-A; tyrosine permease 1; Similar to: HI0477, TYRP_HAEIN; tyrosine-specific transport protein 1 569575 tyrP 3429918 tyrP Haemophilus influenzae 86-028NP tyrosine-specific transport protein 1 YP_248191.1 568373 D 281310 CDS YP_248192.1 68249080 3429919 complement(569761..570189) 1 NC_007146.2 ATP synthase F1 sector epsilon subunit; part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 570189 atpC 3429919 atpC Haemophilus influenzae 86-028NP ATP synthase F0F1 subunit epsilon YP_248192.1 569761 R 281310 CDS YP_248193.1 68249081 3429920 complement(570219..571592) 1 NC_007146.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 571592 atpD 3429920 atpD Haemophilus influenzae 86-028NP ATP synthase F0F1 subunit beta YP_248193.1 570219 R 281310 CDS YP_248194.1 68249082 3429921 complement(571609..572478) 1 NC_007146.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 572478 atpG 3429921 atpG Haemophilus influenzae 86-028NP ATP synthase F0F1 subunit gamma YP_248194.1 571609 R 281310 CDS YP_248195.1 68249083 3429922 complement(572494..574035) 1 NC_007146.2 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 574035 atpA 3429922 atpA Haemophilus influenzae 86-028NP ATP synthase F0F1 subunit alpha YP_248195.1 572494 R 281310 CDS YP_248196.1 68249084 3429923 complement(574048..574581) 1 NC_007146.2 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 574581 atpH 3429923 atpH Haemophilus influenzae 86-028NP ATP synthase F0F1 subunit delta YP_248196.1 574048 R 281310 CDS YP_248197.1 68249085 3429924 complement(574594..575064) 1 NC_007146.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 575064 atpF 3429924 atpF Haemophilus influenzae 86-028NP ATP synthase F0F1 subunit B YP_248197.1 574594 R 281310 CDS YP_248198.1 68249086 3429925 complement(575114..575368) 1 NC_007146.2 Lipid-binding protein; dicyclohexylcarbodiimide-binding protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 575368 atpE 3429925 atpE Haemophilus influenzae 86-028NP ATP synthase F0F1 subunit C YP_248198.1 575114 R 281310 CDS YP_248199.1 68249087 3429926 complement(575424..576212) 1 NC_007146.2 protein 6; Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 576212 atpB 3429926 atpB Haemophilus influenzae 86-028NP ATP synthase F0F1 subunit A YP_248199.1 575424 R 281310 CDS YP_248200.1 68249088 3429927 complement(576249..576623) 1 NC_007146.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 576623 3429927 NTHI0616 Haemophilus influenzae 86-028NP F0F1 ATP synthase subunit I YP_248200.1 576249 R 281310 CDS YP_248201.1 68249089 3429928 complement(576749..577360) 1 NC_007146.2 glucose inhibited division protein B; glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 577360 gidB 3429928 gidB Haemophilus influenzae 86-028NP 16S rRNA methyltransferase GidB YP_248201.1 576749 R 281310 CDS YP_248202.1 68249090 3429929 complement(577500..577877) 1 NC_007146.2 Similar to: HI0487, YHFY_HAEIN; hypothetical protein 577877 3429929 NTHI0618 Haemophilus influenzae 86-028NP hypothetical protein YP_248202.1 577500 R 281310 CDS YP_248203.1 68249091 3429930 577993..578595 1 NC_007146.2 Similar to: HI0488, YQAB_HAEIN; phosphatase/phosphohexomutase 578595 3429930 NTHI0619 Haemophilus influenzae 86-028NP phosphatase/phosphohexomutase YP_248203.1 577993 D 281310 CDS YP_248204.1 68249092 3429931 578595..579068 1 NC_007146.2 Similar to: HI0489, YQAA_HAEIN; hypothetical protein 579068 3429931 NTHI0620 Haemophilus influenzae 86-028NP hypothetical protein YP_248204.1 578595 D 281310 CDS YP_248205.1 68249093 3429932 579253..579756 1 NC_007146.2 autoinducer-2 production protein LuxS; AI-2 synthesis protein; catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 579756 luxS 3429932 luxS Haemophilus influenzae 86-028NP S-ribosylhomocysteinase YP_248205.1 579253 D 281310 CDS YP_248206.1 68249094 3429933 complement(580700..581407) 1 NC_007146.2 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 581407 aphA 3429933 aphA Haemophilus influenzae 86-028NP acid phosphatase/phosphotransferase YP_248206.1 580700 R 281310 CDS YP_248207.1 68249095 3429934 581627..582154 1 NC_007146.2 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 582154 hslV 3429934 hslV Haemophilus influenzae 86-028NP ATP-dependent protease peptidase subunit YP_248207.1 581627 D 281310 CDS YP_248208.1 68249096 3429935 582165..583499 1 NC_007146.2 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 583499 hslU 3429935 hslU Haemophilus influenzae 86-028NP ATP-dependent protease ATP-binding subunit HslU YP_248208.1 582165 D 281310 CDS YP_248209.1 68249097 3429936 complement(583569..584621) 1 NC_007146.2 SPBP; Similar to: HI0498, POT2_HAEIN; spermidine/putrescine-binding periplasmic protein 2 584621 potD2 3429936 potD2 Haemophilus influenzae 86-028NP spermidine/putrescine-binding periplasmic protein 2 YP_248209.1 583569 R 281310 CDS YP_248210.1 68249098 3429937 584761..586056 1 NC_007146.2 Similar to: HI0499, ORDL_HAEIN; oxidoreductase OrdL 586056 ordL 3429937 ordL Haemophilus influenzae 86-028NP oxidoreductase OrdL YP_248210.1 584761 D 281310 CDS YP_248211.1 68249099 3429938 586220..587662 1 NC_007146.2 Similar to: HI0500, RMUC_HAEIN; DNA recombination protein RmuC 587662 rmuC 3429938 rmuC Haemophilus influenzae 86-028NP DNA recombination protein RmuC YP_248211.1 586220 D 281310 CDS YP_248212.1 68249100 3429939 587826..588245 1 NC_007146.2 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 588245 rbsD 3429939 rbsD Haemophilus influenzae 86-028NP D-ribose pyranase YP_248212.1 587826 D 281310 CDS YP_248213.1 68249101 3429940 588259..589740 1 NC_007146.2 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 589740 rbsA 3429940 rbsA Haemophilus influenzae 86-028NP D-ribose transporter ATP binding protein YP_248213.1 588259 D 281310 CDS YP_248214.1 68249102 3429941 589753..590724 1 NC_007146.2 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease protein 590724 rbsC 3429941 rbsC Haemophilus influenzae 86-028NP ribose ABC transporter permease protein YP_248214.1 589753 D 281310 CDS YP_248215.1 68249103 3429942 590744..591622 1 NC_007146.2 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 591622 rbsB 3429942 rbsB Haemophilus influenzae 86-028NP D-ribose transporter subunit RbsB YP_248215.1 590744 D 281310 CDS YP_248216.1 68249104 3429943 591720..592640 1 NC_007146.2 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 592640 rbsK 3429943 rbsK Haemophilus influenzae 86-028NP ribokinase YP_248216.1 591720 D 281310 CDS YP_248217.1 68249105 3429944 592668..593666 1 NC_007146.2 Similar to: HI0506, RBSR_HAEIN; ribose operon repressor 593666 rbsR 3429944 rbsR Haemophilus influenzae 86-028NP ribose operon repressor YP_248217.1 592668 D 281310 CDS YP_248218.1 68249106 3429945 593772..594323 1 NC_007146.2 Similar to: HI0507, YQHA_HAEIN; hypothetical protein 594323 3429945 NTHI0635 Haemophilus influenzae 86-028NP hypothetical protein YP_248218.1 593772 D 281310 CDS YP_248219.1 68249107 3429946 complement(594463..594951) 1 NC_007146.2 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 594951 menG 3429946 menG Haemophilus influenzae 86-028NP ribonuclease activity regulator protein RraA YP_248219.1 594463 R 281310 CDS YP_248220.1 68249108 3429947 complement(595003..595935) 1 NC_007146.2 DHNA-octaprenyltransferase; catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 595935 menA 3429947 menA Haemophilus influenzae 86-028NP 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_248220.1 595003 R 281310 CDS YP_248221.1 68249109 3429948 595982..596701 1 NC_007146.2 Similar to: HI0510, YAEB_HAEIN; hypothetical protein 596701 3429948 NTHI0638 Haemophilus influenzae 86-028NP hypothetical protein YP_248221.1 595982 D 281310 CDS YP_248222.1 68249110 3429949 complement(596754..597740) 1 NC_007146.2 Similar to: HI0511, TEHA_HAEIN; potassium-tellurite ethidium and proflavin transporter 597740 tehA 3429949 tehA Haemophilus influenzae 86-028NP potassium-tellurite ethidium and proflavin transporter YP_248222.1 596754 R 281310 CDS YP_248223.1 68249111 3429950 complement(597892..602142) 1 NC_007146.2 transcriptase beta' chain; RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 602142 rpoC 3429950 rpoC Haemophilus influenzae 86-028NP DNA-directed RNA polymerase subunit beta' YP_248223.1 597892 R 281310 CDS YP_248224.1 68249112 3429951 complement(602349..606380) 1 NC_007146.2 transcriptase beta chain; RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 606380 rpoB 3429951 rpoB Haemophilus influenzae 86-028NP DNA-directed RNA polymerase subunit beta YP_248224.1 602349 R 281310 CDS YP_248225.1 68249113 3429952 complement(606764..607453) 1 NC_007146.2 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 607453 rplA 3429952 rplA Haemophilus influenzae 86-028NP 50S ribosomal protein L1 YP_248225.1 606764 R 281310 CDS YP_248226.1 68249114 3429953 complement(607458..607886) 1 NC_007146.2 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 607886 rplK 3429953 rplK Haemophilus influenzae 86-028NP 50S ribosomal protein L11 YP_248226.1 607458 R 281310 CDS YP_248227.1 68249115 3429954 complement(608059..608775) 1 NC_007146.2 inosine phosphorylase; PNP; catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 608775 deoD 3429954 deoD Haemophilus influenzae 86-028NP purine nucleoside phosphorylase YP_248227.1 608059 R 281310 CDS YP_248228.1 68249116 3429955 complement(608859..610112) 1 NC_007146.2 Similar to: HI0519, YEIM_HAEIN; nucleoside permease 610112 3429955 NTHI0645 Haemophilus influenzae 86-028NP nucleoside permease YP_248228.1 608859 R 281310 CDS YP_248229.1 68249117 3429956 complement(610211..610999) 1 NC_007146.2 Similar to: HI0520, Y520_HAEIN; pyruvate-formate lyase-activating enzyme 610999 3429956 NTHI0646 Haemophilus influenzae 86-028NP pyruvate-formate lyase-activating enzyme YP_248229.1 610211 R 281310 CDS YP_248230.1 68249118 3429957 complement(611008..612552) 1 NC_007146.2 Similar to: HI0521, YJJI_HAEIN; hypothetical protein 612552 3429957 NTHI0647 Haemophilus influenzae 86-028NP hypothetical protein YP_248230.1 611008 R 281310 CDS YP_248231.1 68249119 3429958 612765..613421 1 NC_007146.2 Similar to: HI0522, Y522_HAEIN; hypothetical protein 613421 3429958 NTHI0648 Haemophilus influenzae 86-028NP hypothetical protein YP_248231.1 612765 D 281310 CDS YP_248232.1 68249120 3429959 complement(613377..614447) 1 NC_007146.2 Similar to: HI0523, Y523_HAEIN; ADP-heptose--lipooligosaccharide heptosyltransferase III 614447 waaQ 3429959 waaQ Haemophilus influenzae 86-028NP ADP-heptose--lipooligosaccharide heptosyltransferase III YP_248232.1 613377 R 281310 CDS YP_248233.1 68249121 3429960 complement(614485..615564) 1 NC_007146.2 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 615564 fba 3429960 fba Haemophilus influenzae 86-028NP fructose-bisphosphate aldolase YP_248233.1 614485 R 281310 CDS YP_248234.1 68249122 3429961 complement(615675..616835) 1 NC_007146.2 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 616835 pgk 3429961 pgk Haemophilus influenzae 86-028NP phosphoglycerate kinase YP_248234.1 615675 R 281310 CDS YP_248235.1 68249123 3429962 complement(616931..617725) 1 NC_007146.2 Similar to: HI0526, RN26_HAEIN; ribonuclease I 617725 3429962 NTHI0652 Haemophilus influenzae 86-028NP ribonuclease I YP_248235.1 616931 R 281310 CDS YP_248236.1 68249124 3429963 617803..618063 1 NC_007146.2 Similar to: HI0527, YFHL_HAEIN; ferredoxin-like protein 618063 3429963 NTHI0653 Haemophilus influenzae 86-028NP ferredoxin-like protein YP_248236.1 617803 D 281310 CDS YP_248237.1 68249125 3429964 complement(618197..619417) 1 NC_007146.2 TyrP-B; tyrosine permease 2; Similar to: HI0528, TYRQ_HAEIN; tyrosine-specific transport protein 2 619417 tyrQ 3429964 tyrQ Haemophilus influenzae 86-028NP tyrosine-specific transport protein 2 YP_248237.1 618197 R 281310 CDS YP_248238.1 68249126 3429965 complement(619454..620035) 1 NC_007146.2 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 620035 tdk 3429965 tdk Haemophilus influenzae 86-028NP thymidine kinase YP_248238.1 619454 R 281310 CDS YP_248239.1 68249127 3429966 complement(620044..621072) 1 NC_007146.2 glycoprotease; in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 621072 gcp 3429966 gcp Haemophilus influenzae 86-028NP DNA-binding/iron metalloprotein/AP endonuclease YP_248239.1 620044 R 281310 CDS YP_248240.1 68249128 3429967 621304..621519 1 NC_007146.2 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 621519 rpsU 3429967 rpsU Haemophilus influenzae 86-028NP 30S ribosomal protein S21 YP_248240.1 621304 D 281310 CDS YP_248241.1 68249129 3429968 621653..623434 1 NC_007146.2 synthesizes RNA primers at the replication forks; DNA primase 623434 dnaG 3429968 dnaG Haemophilus influenzae 86-028NP DNA primase YP_248241.1 621653 D 281310 CDS YP_248242.1 68249130 3429969 623505..625376 1 NC_007146.2 Sigma-70; Similar to: HI0533, RPSD_HAEIN; RNA polymerase sigma factor RpoD 625376 rpoD 3429969 rpoD Haemophilus influenzae 86-028NP RNA polymerase sigma factor RpoD YP_248242.1 623505 D 281310 CDS YP_248243.1 68249131 3429970 complement(625686..627113) 1 NC_007146.2 aspartase; catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 627113 aspA 3429970 aspA Haemophilus influenzae 86-028NP aspartate ammonia-lyase YP_248243.1 625686 R 281310 CDS YP_248244.1 68249132 3429971 complement(627260..628075) 1 NC_007146.2 Similar to: HI0535, UREH_HAEIN; urease accessory protein UreH 628075 ureH 3429971 ureH Haemophilus influenzae 86-028NP urease accessory protein UreH YP_248244.1 627260 R 281310 CDS YP_248245.1 68249133 3429972 complement(628150..628827) 1 NC_007146.2 Similar to: HI0536, UREG_HAEIN; urease accessory protein 628827 ureG 3429972 ureG Haemophilus influenzae 86-028NP urease accessory protein YP_248245.1 628150 R 281310 CDS YP_248246.1 68249134 3429973 complement(628930..629637) 1 NC_007146.2 Similar to: HI0537, UREF_HAEIN; urease accessory protein UreF 629637 ureF 3429973 ureF Haemophilus influenzae 86-028NP urease accessory protein UreF YP_248246.1 628930 R 281310 CDS YP_248247.1 68249135 3429974 complement(629622..630179) 1 NC_007146.2 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 630179 ureE 3429974 ureE Haemophilus influenzae 86-028NP urease accessory protein UreE YP_248247.1 629622 R 281310 CDS YP_248248.1 68249136 3429975 complement(630307..632025) 1 NC_007146.2 Urea amidohydrolase; ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 632025 ureC 3429975 ureC Haemophilus influenzae 86-028NP urease subunit alpha YP_248248.1 630307 R 281310 CDS YP_248249.1 68249137 3429976 complement(632037..632342) 1 NC_007146.2 Urea amidohydrolase; ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 632342 ureB 3429976 ureB Haemophilus influenzae 86-028NP urease subunit beta YP_248249.1 632037 R 281310 CDS YP_248250.1 68249138 3429977 complement(632419..632721) 1 NC_007146.2 Urea amidohydrolase gamma subunit; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 632721 ureA 3429977 ureA Haemophilus influenzae 86-028NP urease subunit gamma YP_248250.1 632419 R 281310 CDS YP_248251.1 68249139 3429978 632884..633174 1 NC_007146.2 Cpn10; groES; 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 633174 groES 3429978 groES Haemophilus influenzae 86-028NP co-chaperonin GroES YP_248251.1 632884 D 281310 CDS YP_248252.1 68249140 3429979 633197..634834 1 NC_007146.2 Cpn60; groEL; 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 634834 groEL 3429979 groEL Haemophilus influenzae 86-028NP molecular chaperone GroEL YP_248252.1 633197 D 281310 CDS YP_248253.1 68249141 3429980 complement(635008..635457) 1 NC_007146.2 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 635457 rplI 3429980 rplI Haemophilus influenzae 86-028NP 50S ribosomal protein L9 YP_248253.1 635008 R 281310 CDS YP_248254.1 68249142 3429981 complement(635474..635701) 1 NC_007146.2 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 635701 rpsR 3429981 rpsR Haemophilus influenzae 86-028NP 30S ribosomal protein S18 YP_248254.1 635474 R 281310 CDS YP_248255.1 68249143 3429982 complement(635714..636040) 1 NC_007146.2 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 636040 priB 3429982 priB Haemophilus influenzae 86-028NP primosomal replication protein N YP_248255.1 635714 R 281310 CDS YP_248256.1 68249144 3429983 complement(636027..636404) 1 NC_007146.2 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 636404 rpsF 3429983 rpsF Haemophilus influenzae 86-028NP 30S ribosomal protein S6 YP_248256.1 636027 R 281310 CDS YP_248257.1 68249145 3429984 complement(636596..636850) 1 NC_007146.2 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 636850 infA 3429984 infA Haemophilus influenzae 86-028NP translation initiation factor IF-1 YP_248257.1 636596 R 281310 CDS YP_248258.1 68249146 3429986 638183..639046 1 NC_007146.2 S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase; 16S rRNA dimethylase; High level kasugamycin resistance protein ksgA; kasugamycin dimethyltransferase; catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 639046 ksgA 3429986 ksgA Haemophilus influenzae 86-028NP dimethyladenosine transferase YP_248258.1 638183 D 281310 CDS YP_248259.1 68249147 3429987 complement(639086..640024) 1 NC_007146.2 Similar to: HI0550, LEX1_HAEIN; UDP-Gal--lipooligosaccharide galactosyltransferase 640024 lic2A 3429987 lic2A Haemophilus influenzae 86-028NP UDP-Gal--lipooligosaccharide galactosyltransferase YP_248259.1 639086 R 281310 CDS YP_248260.1 68249148 3429988 640077..640904 1 NC_007146.2 5'-nucleosyl; diadenosine tetraphosphatase; Ap4A hydrolase; diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 640904 apaH 3429988 apaH Haemophilus influenzae 86-028NP diadenosine tetraphosphatase YP_248260.1 640077 D 281310 CDS YP_248261.1 68249149 3429989 640914..641537 1 NC_007146.2 Similar to: HI0552, Y552_HAEIN; hypothetical protein 641537 3429989 NTHI0680 Haemophilus influenzae 86-028NP hypothetical protein YP_248261.1 640914 D 281310 CDS YP_248262.1 68249150 3429990 complement(641663..643117) 1 NC_007146.2 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 643117 gnd 3429990 gnd Haemophilus influenzae 86-028NP 6-phosphogluconate dehydrogenase YP_248262.1 641663 R 281310 CDS YP_248263.1 68249151 3429991 complement(643233..643775) 1 NC_007146.2 Similar to: HI0554, Y554_HAEIN; hypothetical protein 643775 3429991 NTHI0683 Haemophilus influenzae 86-028NP hypothetical protein YP_248263.1 643233 R 281310 CDS YP_248264.1 68249152 3429992 complement(643858..644046) 1 NC_007146.2 hypothetical protein 644046 3429992 NTHI0684 Haemophilus influenzae 86-028NP hypothetical protein YP_248264.1 643858 R 281310 CDS YP_248265.2 161761278 3429993 complement(644116..644814) 1 NC_007146.2 6PGL; catalyzes the formation of 6-phospho-D-gluconate from 6-phospho-D-glucono-1,5-lactone; 6-phosphogluconolactonase 644814 devB 3429993 devB Haemophilus influenzae 86-028NP 6-phosphogluconolactonase YP_248265.2 644116 R 281310 CDS YP_248266.1 68249154 3429994 complement(644957..646441) 1 NC_007146.2 G6PD; catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 646441 zwf 3429994 zwf Haemophilus influenzae 86-028NP glucose-6-phosphate 1-dehydrogenase YP_248266.1 644957 R 281310 CDS YP_248267.1 68249155 3429995 complement(646517..647326) 1 NC_007146.2 Similar to: HI0559, CYSQ_HAEIN; CysQ 647326 cysQ 3429995 cysQ Haemophilus influenzae 86-028NP CysQ YP_248267.1 646517 R 281310 CDS YP_248268.1 68249156 3429996 complement(647331..647747) 1 NC_007146.2 Similar to: HI0559.1, Y55A_HAEIN; hypothetical protein 647747 3429996 NTHI0688 Haemophilus influenzae 86-028NP hypothetical protein YP_248268.1 647331 R 281310 CDS YP_248269.1 68249157 3429997 complement(647804..649786) 1 NC_007146.2 Similar to: HI0561, Y561_HAEIN; hypothetical protein 649786 3429997 NTHI0689 Haemophilus influenzae 86-028NP hypothetical protein YP_248269.1 647804 R 281310 CDS YP_248270.1 68249158 3429998 650015..650410 1 NC_007146.2 HSP15; Similar to: HI0562, HSLR_HAEIN; heat shock protein 15-like protein 650410 hslR 3429998 hslR Haemophilus influenzae 86-028NP heat shock protein 15-like protein YP_248270.1 650015 D 281310 CDS YP_248271.1 68249159 3429999 complement(650436..650888) 1 NC_007146.2 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 650888 asnC 3429999 asnC Haemophilus influenzae 86-028NP DNA-binding transcriptional regulator AsnC YP_248271.1 650436 R 281310 CDS YP_248272.1 68249160 3430000 651042..652034 1 NC_007146.2 asparagine synthetase A; catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 652034 asnA 3430000 asnA Haemophilus influenzae 86-028NP asparagine synthetase AsnA YP_248272.1 651042 D 281310 CDS YP_248273.1 68249161 3430001 complement(652097..652450) 1 NC_007146.2 Similar to: HI1721, YH21_HAEIN; transposase-like protein 652450 3430001 NTHI0693 Haemophilus influenzae 86-028NP transposase-like protein YP_248273.1 652097 R 281310 CDS YP_248274.1 68249162 3430002 653063..653920 1 NC_007146.2 hypothetical protein 653920 3430002 NTHI0694 Haemophilus influenzae 86-028NP hypothetical protein YP_248274.1 653063 D 281310 CDS YP_248275.1 68249163 3430003 complement(654077..654193) 1 NC_007146.2 hypothetical protein 654193 3430003 NTHI0695 Haemophilus influenzae 86-028NP hypothetical protein YP_248275.1 654077 R 281310 CDS YP_248276.1 68249164 3430004 654485..654625 1 NC_007146.2 hypothetical protein 654625 3430004 NTHI0696 Haemophilus influenzae 86-028NP hypothetical protein YP_248276.1 654485 D 281310 CDS YP_248277.1 68249165 3430005 complement(654805..655479) 1 NC_007146.2 PGP; catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 655479 gph 3430005 gph Haemophilus influenzae 86-028NP phosphoglycolate phosphatase YP_248277.1 654805 R 281310 CDS YP_248278.1 68249166 3430006 complement(655525..656229) 1 NC_007146.2 pentose-5-phosphate 3-epimerase; PPE; R5P3E; catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 656229 rpe 3430006 rpe Haemophilus influenzae 86-028NP ribulose-phosphate 3-epimerase YP_248278.1 655525 R 281310 CDS YP_248279.1 68249167 3430007 complement(656351..658771) 1 NC_007146.2 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 658771 gyrB 3430007 gyrB Haemophilus influenzae 86-028NP DNA gyrase subunit B YP_248279.1 656351 R 281310 CDS YP_248280.1 68249168 3430008 complement(658897..661209) 1 NC_007146.2 Similar to: HI0568, YHGF_HAEIN; transcriptional accessory protein 661209 3430008 NTHI0701 Haemophilus influenzae 86-028NP transcriptional accessory protein YP_248280.1 658897 R 281310 CDS YP_248281.1 68249169 3430009 661305..661781 1 NC_007146.2 transcript cleavage factor greB; necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 661781 greB 3430009 greB Haemophilus influenzae 86-028NP transcription elongation factor GreB YP_248281.1 661305 D 281310 CDS YP_248282.1 68249170 3430010 complement(661851..662468) 1 NC_007146.2 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 662468 3430010 NTHI0703 Haemophilus influenzae 86-028NP DNA-binding transcriptional repressor FabR YP_248282.1 661851 R 281310 CDS YP_248283.1 68249171 3430011 complement(662468..663373) 1 NC_007146.2 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 663373 oxyR 3430011 oxyR Haemophilus influenzae 86-028NP DNA-binding transcriptional regulator OxyR YP_248283.1 662468 R 281310 CDS YP_248284.1 68249172 3430012 663496..664221 1 NC_007146.2 Similar to: HI0572, Y572_HAEIN; peroxiredoxin/glutaredoxin 664221 pdgX 3430012 pdgX Haemophilus influenzae 86-028NP peroxiredoxin/glutaredoxin YP_248284.1 663496 D 281310 CDS YP_248285.1 68249173 3430013 complement(664313..664534) 1 NC_007146.2 Similar to: HI0573, SLYX_HAEIN; hypothetical protein 664534 slyX 3430013 slyX Haemophilus influenzae 86-028NP hypothetical protein YP_248285.1 664313 R 281310 CDS YP_248286.1 68249174 3430014 664632..665357 1 NC_007146.2 PPIase; rotamase; Similar to: HI0574, FKBY_HAEIN; FKBP-type peptidylprolyl isomerase 665357 fkbY 3430014 fkbY Haemophilus influenzae 86-028NP FKBP-type peptidylprolyl isomerase YP_248286.1 664632 D 281310 CDS YP_248287.1 68249175 3430015 665447..666112 1 NC_007146.2 Similar to: HI0575, YHEO_HAEIN; hypothetical protein 666112 3430015 NTHI0708 Haemophilus influenzae 86-028NP hypothetical protein YP_248287.1 665447 D 281310 CDS YP_248288.1 68249176 3430016 666112..666492 1 NC_007146.2 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 666492 3430016 NTHI0709 Haemophilus influenzae 86-028NP sulfur transfer complex subunit TusD YP_248288.1 666112 D 281310 CDS YP_248289.1 68249177 3430017 666489..666848 1 NC_007146.2 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 666848 3430017 NTHI0710 Haemophilus influenzae 86-028NP sulfur relay protein TusC YP_248289.1 666489 D 281310 CDS YP_248290.1 68249178 3430018 666857..667144 1 NC_007146.2 Similar to: HI0577, Y577_HAEIN; hypothetical protein 667144 3430018 NTHI0711 Haemophilus influenzae 86-028NP hypothetical protein YP_248290.1 666857 D 281310 CDS YP_248291.1 68249179 3430019 complement(667275..668459) 1 NC_007146.2 EF-Tu; EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 668459 tuf 3430019 tuf Haemophilus influenzae 86-028NP elongation factor Tu YP_248291.1 667275 R 281310 CDS YP_248292.1 68249180 3430024 669165..670088 1 NC_007146.2 pantothenic acid kinase; catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 670088 coaA 3430024 coaA Haemophilus influenzae 86-028NP pantothenate kinase YP_248292.1 669165 D 281310 CDS YP_248293.1 68249181 3430025 complement(670179..671126) 1 NC_007146.2 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 671126 rseB 3430025 rseB Haemophilus influenzae 86-028NP periplasmic negative regulator of sigmaE YP_248293.1 670179 R 281310 CDS YP_248294.1 68249182 3430026 complement(671206..671781) 1 NC_007146.2 Similar to: HI0629, RSEA_HAEIN; sigma-E factor negative regulatory protein 671781 rseA 3430026 rseA Haemophilus influenzae 86-028NP sigma-E factor negative regulatory protein YP_248294.1 671206 R 281310 CDS YP_248295.1 68249183 3430027 complement(671806..672375) 1 NC_007146.2 Sigma-24; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 672375 rpoE 3430027 rpoE Haemophilus influenzae 86-028NP RNA polymerase sigma factor RpoE YP_248295.1 671806 R 281310 CDS YP_248296.1 68249184 3430028 complement(672484..672741) 1 NC_007146.2 Similar to: HI0627, YGFY_HAEIN; hypothetical protein 672741 3430028 NTHI0720 Haemophilus influenzae 86-028NP hypothetical protein YP_248296.1 672484 R 281310 CDS YP_248297.1 68249185 3430029 complement(672831..673217) 1 NC_007146.2 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 673217 mscL 3430029 mscL Haemophilus influenzae 86-028NP large-conductance mechanosensitive channel YP_248297.1 672831 R 281310 CDS YP_248298.1 68249186 3430030 complement(673290..674666) 1 NC_007146.2 K(+)-uptake protein trkA; involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 674666 trkA 3430030 trkA Haemophilus influenzae 86-028NP potassium transporter peripheral membrane component YP_248298.1 673290 R 281310 CDS YP_248299.1 68249187 3430031 complement(674679..676031) 1 NC_007146.2 FMU protein; predicted tRNA or rRNA cytosine-C5-methylase; Similar to: HI0624, SUN_HAEIN; SUN protein 676031 sun 3430031 sun Haemophilus influenzae 86-028NP SUN protein YP_248299.1 674679 R 281310 CDS YP_248300.1 68249188 3430032 complement(676031..676987) 1 NC_007146.2 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 676987 fmt 3430032 fmt Haemophilus influenzae 86-028NP methionyl-tRNA formyltransferase YP_248300.1 676031 R 281310 CDS YP_248301.1 68249189 3430033 complement(677088..677597) 1 NC_007146.2 PDF; polypeptide deformylase; cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 677597 def 3430033 def Haemophilus influenzae 86-028NP peptide deformylase YP_248301.1 677088 R 281310 CDS YP_248302.1 68249190 3430034 complement(677787..678224) 1 NC_007146.2 hypothetical protein 678224 3430034 NTHI0726 Haemophilus influenzae 86-028NP hypothetical protein YP_248302.1 677787 R 281310 CDS YP_248303.1 68249191 3430035 complement(678202..678387) 1 NC_007146.2 hypothetical protein 678387 3430035 NTHI0727 Haemophilus influenzae 86-028NP hypothetical protein YP_248303.1 678202 R 281310 CDS YP_248304.1 68249192 3430041 complement(684668..685321) 1 NC_007146.2 competence activator; protein sxy; Similar to: HI0601, TFOX_HAEIN; DNA transformation protein TfoX 685321 sxy 3430041 sxy Haemophilus influenzae 86-028NP DNA transformation protein TfoX YP_248304.1 684668 R 281310 CDS YP_248305.1 68249193 3430042 685693..686757 1 NC_007146.2 recombinase A; recombinase 1; catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 686757 recA 3430042 recA Haemophilus influenzae 86-028NP recombinase A YP_248305.1 685693 D 281310 CDS YP_248306.1 68249194 3430043 686836..687294 1 NC_007146.2 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 687294 recX 3430043 recX Haemophilus influenzae 86-028NP recombination regulator RecX YP_248306.1 686836 D 281310 CDS YP_248307.1 68249195 3430044 complement(687291..687677) 1 NC_007146.2 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 687677 ccrB 3430044 ccrB Haemophilus influenzae 86-028NP camphor resistance protein CrcB YP_248307.1 687291 R 281310 CDS YP_248308.1 68249196 3430045 complement(687677..688495) 1 NC_007146.2 Similar to: HI0597, YIGL_HAEIN; HAD superfamily hydrolase 688495 3430045 NTHI0732 Haemophilus influenzae 86-028NP HAD superfamily hydrolase YP_248308.1 687677 R 281310 CDS YP_248309.1 68249197 3430046 688898..689902 1 NC_007146.2 OTCase; Similar to: HI0596, OTCC_HAEIN; ornithine carbamoyltransferase 689902 argF 3430046 argF Haemophilus influenzae 86-028NP ornithine carbamoyltransferase YP_248309.1 688898 D 281310 CDS YP_248310.1 68249198 3430047 689912..690844 1 NC_007146.2 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 690844 arcC 3430047 arcC Haemophilus influenzae 86-028NP carbamate kinase YP_248310.1 689912 D 281310 CDS YP_248311.1 68249199 3430048 690949..692478 1 NC_007146.2 Similar to: HI0594, YFCC_HAEIN; hypothetical protein 692478 3430048 NTHI0735 Haemophilus influenzae 86-028NP hypothetical protein YP_248311.1 690949 D 281310 CDS YP_248312.1 68249200 3430050 697114..697818 1 NC_007146.2 alpha-aspartyl dipeptidase; Asp-specific dipeptidase; dipeptidase E; alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 697818 pepE 3430050 pepE Haemophilus influenzae 86-028NP peptidase E YP_248312.1 697114 D 281310 CDS YP_248313.1 68249201 3430051 697836..699131 1 NC_007146.2 Similar to: HI0585, Y585_HAEIN; C4-dicarboxylate transporter 699131 3430051 NTHI0739 Haemophilus influenzae 86-028NP C4-dicarboxylate transporter YP_248313.1 697836 D 281310 CDS YP_248314.1 68249202 3430052 699203..700474 1 NC_007146.2 Similar to: HI0584, ABGA_HAEIN; aminobenzoyl-glutamate utilization protein A 700474 abgA 3430052 abgA Haemophilus influenzae 86-028NP aminobenzoyl-glutamate utilization protein A YP_248314.1 699203 D 281310 CDS YP_248315.1 68249203 3430053 700567..702540 1 NC_007146.2 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 702540 cpdB 3430053 cpdB Haemophilus influenzae 86-028NP bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_248315.1 700567 D 281310 CDS YP_248316.1 68249204 3430054 complement(702649..703056) 1 NC_007146.2 HTH-type transcriptional regulator 703056 3430054 NTHI0742 Haemophilus influenzae 86-028NP HTH-type transcriptional regulator YP_248316.1 702649 R 281310 CDS YP_248317.1 68249205 3430055 complement(703066..703743) 1 NC_007146.2 zinc transporter ZitB 703743 3430055 NTHI0743 Haemophilus influenzae 86-028NP zinc transporter ZitB YP_248317.1 703066 R 281310 CDS YP_248318.1 68249206 3430056 704251..706140 1 NC_007146.2 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 706140 gidA 3430056 gidA Haemophilus influenzae 86-028NP tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_248318.1 704251 D 281310 CDS YP_248319.1 68249207 3430057 706322..706696 1 NC_007146.2 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 706696 rpsL 3430057 rpsL Haemophilus influenzae 86-028NP 30S ribosomal protein S12 YP_248319.1 706322 D 281310 CDS YP_248320.1 68249208 3430058 706853..707323 1 NC_007146.2 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 707323 rpsG 3430058 rpsG Haemophilus influenzae 86-028NP 30S ribosomal protein S7 YP_248320.1 706853 D 281310 CDS YP_248321.1 68249209 3430059 707407..709509 1 NC_007146.2 EF-G; EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 709509 fusA 3430059 fusA Haemophilus influenzae 86-028NP elongation factor G YP_248321.1 707407 D 281310 CDS YP_248322.1 68249210 3430060 709574..710758 1 NC_007146.2 EF-Tu; EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 710758 tuf 3430060 tuf Haemophilus influenzae 86-028NP elongation factor Tu YP_248322.1 709574 D 281310 CDS YP_248323.1 68249211 3430061 711218..711562 1 NC_007146.2 chloride channel protein 711562 3430061 NTHI0749 Haemophilus influenzae 86-028NP chloride channel protein YP_248323.1 711218 D 281310 CDS YP_248324.1 68249212 3430062 711553..711735 1 NC_007146.2 Similar to: HI0633; chloride channel protein 711735 3430062 NTHI0751 Haemophilus influenzae 86-028NP chloride channel protein YP_248324.1 711553 D 281310 CDS YP_248325.1 68249213 3430063 711738..712721 1 NC_007146.2 Similar to: HI0634, DUSA_HAEIN; tRNA-dihydrouridine synthase A 712721 dusA 3430063 dusA Haemophilus influenzae 86-028NP tRNA-dihydrouridine synthase A YP_248325.1 711738 D 281310 CDS YP_248326.1 68249214 3430064 complement(712769..713059) 1 NC_007146.2 Similar to: HI0636, Y636_HAEIN; hypothetical protein 713059 3430064 NTHI0754 Haemophilus influenzae 86-028NP hypothetical protein YP_248326.1 712769 R 281310 CDS YP_248327.1 68249215 3430065 complement(713082..714092) 1 NC_007146.2 tryptophan--tRNA ligase; TrpRS; catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 714092 trpS 3430065 trpS Haemophilus influenzae 86-028NP tryptophanyl-tRNA synthetase YP_248327.1 713082 R 281310 CDS YP_248328.1 68249216 3430066 714215..714832 1 NC_007146.2 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 714832 3430066 NTHI0757 Haemophilus influenzae 86-028NP hypothetical protein YP_248328.1 714215 D 281310 CDS YP_248329.1 68249217 3430067 714855..716225 1 NC_007146.2 adenylosuccinase; ASL; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 716225 purB 3430067 purB Haemophilus influenzae 86-028NP adenylosuccinate lyase YP_248329.1 714855 D 281310 CDS YP_248330.1 68249218 3430068 716497..716988 1 NC_007146.2 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 716988 rplJ 3430068 rplJ Haemophilus influenzae 86-028NP 50S ribosomal protein L10 YP_248330.1 716497 D 281310 CDS YP_248331.1 68249219 3430069 717043..717414 1 NC_007146.2 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 717414 rplL 3430069 rplL Haemophilus influenzae 86-028NP 50S ribosomal protein L7/L12 YP_248331.1 717043 D 281310 CDS YP_248332.1 68249220 3430070 717573..718943 1 NC_007146.2 N-acetylglucosamine-1-phosphate uridyltransferase; forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 718943 glmU 3430070 glmU Haemophilus influenzae 86-028NP bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_248332.1 717573 D 281310 CDS YP_248333.1 68249221 3430071 complement(718978..719289) 1 NC_007146.2 hypothetical protein 719289 3430071 NTHI0763 Haemophilus influenzae 86-028NP hypothetical protein YP_248333.1 718978 R 281310 CDS YP_248334.1 68249222 3430075 complement(719828..720763) 1 NC_007146.2 lecithinase B; Similar to: HI0645, PLDB_HAEIN; lysophospholipase L2 720763 pldB 3430075 pldB Haemophilus influenzae 86-028NP lysophospholipase L2 YP_248334.1 719828 R 281310 CDS YP_248335.1 68249223 3430076 complement(720817..721932) 1 NC_007146.2 ASA dehydrogenase; ASADH; catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 721932 asd 3430076 asd Haemophilus influenzae 86-028NP aspartate-semialdehyde dehydrogenase YP_248335.1 720817 R 281310 CDS YP_248336.1 68249224 3430077 complement(722098..722814) 1 NC_007146.2 Similar to: HI0647, Y647_HAEIN; hypothetical protein 722814 3430077 NTHI0766 Haemophilus influenzae 86-028NP hypothetical protein YP_248336.1 722098 R 281310 CDS YP_248337.1 68249225 3430078 723006..723662 1 NC_007146.2 Similar to: HI0019, YF71_PASMU; 2-methylthioadenine synthetase 723662 3430078 NTHI0767 Haemophilus influenzae 86-028NP 2-methylthioadenine synthetase YP_248337.1 723006 D 281310 CDS YP_248338.1 68249226 3430079 complement(723726..724304) 1 NC_007146.2 Similar to: HI0648, MDAB_HAEIN; NADPH-quinone reductase, modulator of drug activity B 724304 mdaB 3430079 mdaB Haemophilus influenzae 86-028NP NADPH-quinone reductase, modulator of drug activity B YP_248338.1 723726 R 281310 CDS YP_248339.1 68249227 3430080 complement(724583..726595) 1 NC_007146.2 Similar to: HI0649, REP_HAEIN; ATP-dependent DNA helicase 726595 rep 3430080 rep Haemophilus influenzae 86-028NP ATP-dependent DNA helicase YP_248339.1 724583 R 281310 CDS YP_248340.1 68249228 3430081 complement(726601..726813) 1 NC_007146.2 Similar to: HI0650, Y650_HAEIN; periplasmic lipoprotein 726813 3430081 NTHI0770 Haemophilus influenzae 86-028NP periplasmic lipoprotein YP_248340.1 726601 R 281310 CDS YP_248341.1 68249229 3430082 complement(726810..727280) 1 NC_007146.2 pantetheine-phosphate adenylyltransferase; PPAT; dephospho-CoA pyrophosphorylase; Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 727280 coaD 3430082 coaD Haemophilus influenzae 86-028NP phosphopantetheine adenylyltransferase YP_248341.1 726810 R 281310 CDS YP_248342.1 68249230 3430083 complement(727277..728560) 1 NC_007146.2 KDO transferase; catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 728560 kdtA 3430083 kdtA Haemophilus influenzae 86-028NP 3-deoxy-D-manno-octulosonic-acid transferase YP_248342.1 727277 R 281310 CDS YP_248343.1 68249231 3430084 728623..729387 1 NC_007146.2 Similar to: HI0653, Y653_HAEIN; UDP-glucose--lipooligosaccharide glucosyltransferase 729387 lgtF 3430084 lgtF Haemophilus influenzae 86-028NP UDP-glucose--lipooligosaccharide glucosyltransferase YP_248343.1 728623 D 281310 CDS YP_248344.1 68249232 3430085 complement(729384..729947) 1 NC_007146.2 3-methyladenine-DNA glycosidase; TAG; Similar to: HI0654, 3MGA_HAEIN; DNA-3-methyladenine glycosylase 729947 tag 3430085 tag Haemophilus influenzae 86-028NP DNA-3-methyladenine glycosylase YP_248344.1 729384 R 281310 CDS YP_248345.1 68249233 3430086 complement(730062..730814) 1 NC_007146.2 hypothetical protein 730814 3430086 NTHI0775 Haemophilus influenzae 86-028NP hypothetical protein YP_248345.1 730062 R 281310 CDS YP_248346.1 68249234 3430087 complement(730826..731632) 1 NC_007146.2 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 731632 aroE 3430087 aroE Haemophilus influenzae 86-028NP shikimate 5-dehydrogenase YP_248346.1 730826 R 281310 CDS YP_248347.1 68249235 3430088 complement(731636..732187) 1 NC_007146.2 Similar to: HI0656, YRDC_HAEIN; translation factor SUA5 732187 3430088 NTHI0777 Haemophilus influenzae 86-028NP translation factor SUA5 YP_248347.1 731636 R 281310 CDS YP_248348.1 68249236 3430089 complement(732203..732739) 1 NC_007146.2 Similar to: HI0656.1, YRDD_HAEIN; zinc finger domain-containing protein 732739 3430089 NTHI0778 Haemophilus influenzae 86-028NP zinc finger domain-containing protein YP_248348.1 732203 R 281310 CDS YP_248349.1 68249237 3430090 complement(732749..734665) 1 NC_007146.2 Similar to: HI0658, YHES_HAEIN; ABC transporter ATP-binding protein 734665 3430090 NTHI0779 Haemophilus influenzae 86-028NP ABC transporter ATP-binding protein YP_248349.1 732749 R 281310 CDS YP_248350.1 68249238 3430091 complement(734850..735146) 1 NC_007146.2 Similar to: HI0659, Y659_HAEIN; HTH-type transcriptional regulator 735146 3430091 NTHI0780 Haemophilus influenzae 86-028NP HTH-type transcriptional regulator YP_248350.1 734850 R 281310 CDS YP_248351.1 68249239 3430092 complement(735139..735321) 1 NC_007146.2 Similar to: HI0660; hypothetical protein 735321 3430092 NTHI0781 Haemophilus influenzae 86-028NP hypothetical protein YP_248351.1 735139 R 281310 CDS YP_248352.1 68249240 3430093 complement(735591..738569) 1 NC_007146.2 hemoglobin-haptoglobin utilization protein B; Similar to: HI0661, HGPB_HAEIN; hemoglobin-haptoglobin binding protein B 738569 hgpB 3430093 hgpB Haemophilus influenzae 86-028NP hemoglobin-haptoglobin binding protein B YP_248352.1 735591 R 281310 CDS YP_248353.1 68249241 3430094 739300..741045 1 NC_007146.2 Similar to: HI0663, Y663_HAEIN; ABC transporter ATP-binding protein 741045 3430094 NTHI0783 Haemophilus influenzae 86-028NP ABC transporter ATP-binding protein YP_248353.1 739300 D 281310 CDS YP_248354.1 68249242 3430095 741038..742696 1 NC_007146.2 Similar to: HI0664, Y664_HAEIN; ABC transporter ATP-binding protein 742696 3430095 NTHI0785 Haemophilus influenzae 86-028NP ABC transporter ATP-binding protein YP_248354.1 741038 D 281310 CDS YP_248355.1 68249243 3430096 complement(742780..743811) 1 NC_007146.2 Similar to: HI0665, Y665_HAEIN; hypothetical protein 743811 3430096 NTHI0786 Haemophilus influenzae 86-028NP hypothetical protein YP_248355.1 742780 R 281310 CDS YP_248356.1 68249244 3430097 complement(743808..744128) 1 NC_007146.2 Similar to: HI0666, Y666_HAEIN; hypothetical protein 744128 3430097 NTHI0787 Haemophilus influenzae 86-028NP hypothetical protein YP_248356.1 743808 R 281310 CDS YP_248357.1 68249245 3430098 complement(744116..744424) 1 NC_007146.2 Similar to: HI0666.1, Y66A_HAEIN; HTH-type transcriptional regulator 744424 3430098 NTHI0788 Haemophilus influenzae 86-028NP HTH-type transcriptional regulator YP_248357.1 744116 R 281310 CDS YP_248358.1 68249246 3430099 complement(744629..745630) 1 NC_007146.2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class II glpX; FBPase II glpX; type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 745630 glpX 3430099 glpX Haemophilus influenzae 86-028NP fructose 1,6-bisphosphatase II YP_248358.1 744629 R 281310 CDS YP_248359.1 68249247 3430100 745792..746010 1 NC_007146.2 Similar to: HI0668; hypothetical protein 746010 3430100 NTHI0790 Haemophilus influenzae 86-028NP hypothetical protein YP_248359.1 745792 D 281310 CDS YP_248360.1 68249248 3430101 746109..746549 1 NC_007146.2 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 746549 mioC 3430101 mioC Haemophilus influenzae 86-028NP flavodoxin YP_248360.1 746109 D 281310 CDS YP_248361.1 68249249 3430102 746546..746980 1 NC_007146.2 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 746980 dtd 3430102 dtd Haemophilus influenzae 86-028NP D-tyrosyl-tRNA(Tyr) deacylase YP_248361.1 746546 D 281310 CDS YP_248362.1 68249250 3430103 complement(747287..747763) 1 NC_007146.2 MECPS; MECDP-synthase; catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 747763 ispF 3430103 ispF Haemophilus influenzae 86-028NP 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_248362.1 747287 R 281310 CDS YP_248363.1 68249251 3430104 complement(747760..748437) 1 NC_007146.2 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 748437 ispD 3430104 ispD Haemophilus influenzae 86-028NP 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_248363.1 747760 R 281310 CDS YP_248364.1 68249252 3430105 complement(748437..748715) 1 NC_007146.2 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 748715 ftsB 3430105 ftsB Haemophilus influenzae 86-028NP cell division protein FtsB YP_248364.1 748437 R 281310 CDS YP_248365.1 68249253 3430106 complement(748838..749305) 1 NC_007146.2 XGPRT; catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 749305 gpt 3430106 gpt Haemophilus influenzae 86-028NP xanthine-guanine phosphoribosyltransferase YP_248365.1 748838 R 281310 CDS YP_248366.1 68249254 3430107 749416..750870 1 NC_007146.2 Xaa-His dipeptidase; X-His dipeptidase; beta-alanyl-histidine dipeptidase; carnosinase; peptidase D; Similar to: HI0675, PEPD_HAEIN; aminoacyl-histidine dipeptidase 750870 pepD 3430107 pepD Haemophilus influenzae 86-028NP aminoacyl-histidine dipeptidase YP_248366.1 749416 D 281310 CDS YP_248367.1 68249255 3430108 complement(750923..751810) 1 NC_007146.2 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 751810 xerC 3430108 xerC Haemophilus influenzae 86-028NP site-specific tyrosine recombinase XerC YP_248367.1 750923 R 281310 CDS YP_248368.1 68249256 3430109 complement(751804..752244) 1 NC_007146.2 Similar to: HI0677, Y677_HAEIN; hypothetical protein 752244 3430109 NTHI0799 Haemophilus influenzae 86-028NP hypothetical protein YP_248368.1 751804 R 281310 CDS YP_248369.1 68249257 3430110 752410..753201 1 NC_007146.2 TIM; Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 753201 tpiA 3430110 tpiA Haemophilus influenzae 86-028NP triosephosphate isomerase YP_248369.1 752410 D 281310 CDS YP_248370.1 68249258 3430111 complement(753283..753600) 1 NC_007146.2 Similar to: HI0679, GLPE_HAEIN; thiosulfate sulfurtransferase 753600 glpE 3430111 glpE Haemophilus influenzae 86-028NP thiosulfate sulfurtransferase YP_248370.1 753283 R 281310 CDS YP_248371.1 68249259 3430112 complement(753601..754479) 1 NC_007146.2 Similar to: HI0680, Y680_HAEIN; hypothetical protein 754479 3430112 NTHI0802 Haemophilus influenzae 86-028NP hypothetical protein YP_248371.1 753601 R 281310 CDS YP_248372.1 68249260 3430113 complement(754511..755389) 1 NC_007146.2 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 755389 ilvY 3430113 ilvY Haemophilus influenzae 86-028NP DNA-binding transcriptional regulator IlvY YP_248372.1 754511 R 281310 CDS YP_248373.1 68249261 3430114 756073..757551 1 NC_007146.2 acetohydroxy-acid isomeroreductase; alpha-keto-beta-hydroxylacil reductoisomerase; catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 757551 ilvC 3430114 ilvC Haemophilus influenzae 86-028NP ketol-acid reductoisomerase YP_248373.1 756073 D 281310 CDS YP_248374.1 68249262 3430115 complement(757662..758942) 1 NC_007146.2 G-3-P dehydrogenase; anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 758942 glpC 3430115 glpC Haemophilus influenzae 86-028NP sn-glycerol-3-phosphate dehydrogenase subunit C YP_248374.1 757662 R 281310 CDS YP_248375.1 68249263 3430116 complement(758953..760251) 1 NC_007146.2 G-3-P dehydrogenase; sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 760251 glpB 3430116 glpB Haemophilus influenzae 86-028NP anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_248375.1 758953 R 281310 CDS YP_248376.1 68249264 3430117 complement(760241..761932) 1 NC_007146.2 G-3-P dehydrogenase; anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 761932 glpA 3430117 glpA Haemophilus influenzae 86-028NP sn-glycerol-3-phosphate dehydrogenase subunit A YP_248376.1 760241 R 281310 CDS YP_248377.1 68249265 3430118 762225..763667 1 NC_007146.2 G-3-P transporter; G-3-P permease; Similar to: HI0686, GLPT_HAEIN; glycerol-3-phosphate transporter 763667 glpT 3430118 glpT Haemophilus influenzae 86-028NP glycerol-3-phosphate transporter YP_248377.1 762225 D 281310 CDS YP_248378.1 68249266 3430119 763771..764865 1 NC_007146.2 glycerophosphodiester phosphodiesterase; surface-exposed lipoprotein D; hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 764865 glpQ 3430119 glpQ Haemophilus influenzae 86-028NP glycerophosphodiester phosphodiesterase YP_248378.1 763771 D 281310 CDS YP_248379.1 68249267 3430120 765095..765889 1 NC_007146.2 Similar to: HI0690, GLPF_HAEIN; glycerol uptake facilitator protein 765889 glpF 3430120 glpF Haemophilus influenzae 86-028NP glycerol uptake facilitator protein YP_248379.1 765095 D 281310 CDS YP_248380.1 68249268 3430121 765910..767421 1 NC_007146.2 ATP:glycerol 3-phosphotransferase; glycerokinase; GK; Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 767421 glpK 3430121 glpK Haemophilus influenzae 86-028NP glycerol kinase YP_248380.1 765910 D 281310 CDS YP_248381.1 68249269 3430122 complement(767505..767972) 1 NC_007146.2 XGPRT; catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 767972 gpt2 3430122 gpt2 Haemophilus influenzae 86-028NP xanthine-guanine phosphoribosyltransferase YP_248381.1 767505 R 281310 CDS YP_248382.1 68249270 3430124 768257..769081 1 NC_007146.2 lipoprotein E; OMP P4; Similar to: HI0693, HEL_HAEIN; outer membrane protein P4, NADP phosphatase 769081 hel 3430124 hel Haemophilus influenzae 86-028NP outer membrane protein P4, NADP phosphatase YP_248382.1 768257 D 281310 CDS YP_248383.1 68249271 3430125 769248..769931 1 NC_007146.2 pseudouridylate synthase; Uracil hydrolyase; Similar to: HI0694, RLUE_HAEIN; pseudouridylate synthase 769931 rluE 3430125 rluE Haemophilus influenzae 86-028NP pseudouridylate synthase YP_248383.1 769248 D 281310 CDS YP_248384.1 68249272 3430127 complement(771036..774920) 1 NC_007146.2 Similar to: HI0696, YTFN_HAEIN; hypothetical protein 774920 3430127 NTHI0820 Haemophilus influenzae 86-028NP hypothetical protein YP_248384.1 771036 R 281310 CDS YP_248385.1 68249273 3430128 complement(774930..776666) 1 NC_007146.2 Similar to: HI0698, YTFM_HAEIN; hypothetical protein 776666 3430128 NTHI0821 Haemophilus influenzae 86-028NP hypothetical protein YP_248385.1 774930 R 281310 CDS YP_248386.1 68249274 3430129 complement(776817..777389) 1 NC_007146.2 PPIase; rotamase; Similar to: HI0699, SLYD_HAEIN; FKBP-type peptidylprolyl isomerase 777389 slyD 3430129 slyD Haemophilus influenzae 86-028NP FKBP-type peptidylprolyl isomerase YP_248386.1 776817 R 281310 CDS YP_248387.1 68249275 3430130 complement(777467..777889) 1 NC_007146.2 Similar to: HI0700, YJGD_HAEIN; hypothetical protein 777889 3430130 NTHI0823 Haemophilus influenzae 86-028NP hypothetical protein YP_248387.1 777467 R 281310 CDS YP_248388.1 68249276 3430131 777998..779017 1 NC_007146.2 pseudouridylate synthase; Uracil hydrolyase; catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 779017 truD 3430131 truD Haemophilus influenzae 86-028NP tRNA pseudouridine synthase D YP_248388.1 777998 D 281310 CDS YP_248389.1 68249277 3430132 779027..779776 1 NC_007146.2 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 779776 surE 3430132 surE Haemophilus influenzae 86-028NP stationary phase survival protein SurE YP_248389.1 779027 D 281310 CDS YP_248390.1 68249278 3430133 779785..780363 1 NC_007146.2 Similar to: HI0703, Y703_HAEIN; hypothetical protein 780363 3430133 NTHI0826 Haemophilus influenzae 86-028NP hypothetical protein YP_248390.1 779785 D 281310 CDS YP_248391.1 68249279 3430134 780372..780557 1 NC_007146.2 Similar to: HI0704, Y704_HAEIN; hypothetical protein 780557 3430134 NTHI0827 Haemophilus influenzae 86-028NP hypothetical protein YP_248391.1 780372 D 281310 CDS YP_248392.1 68249280 3430135 780592..781809 1 NC_007146.2 Similar to: HI0706, LPPB_HAEIN; lipoprotein 781809 lppB 3430135 lppB Haemophilus influenzae 86-028NP lipoprotein YP_248392.1 780592 D 281310 CDS YP_248393.1 68249281 3430136 782177..783595 1 NC_007146.2 L-tryptophan indole-lyase; TNase; tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 783595 tnaA 3430136 tnaA Haemophilus influenzae 86-028NP tryptophanase YP_248393.1 782177 D 281310 CDS YP_248394.1 68249282 3430137 783679..784911 1 NC_007146.2 tryptophan permease; Similar to: HI0287, MTR_HAEIN; tryptophan-specific transport protein 784911 tnaB 3430137 tnaB Haemophilus influenzae 86-028NP tryptophan-specific transport protein YP_248394.1 783679 D 281310 CDS YP_248395.1 68249283 3430138 785052..787637 1 NC_007146.2 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 787637 mutS 3430138 mutS Haemophilus influenzae 86-028NP DNA mismatch repair protein MutS YP_248395.1 785052 D 281310 CDS YP_248396.1 68249284 3430140 787843..789228 1 NC_007146.2 Sec; cysteinyl-tRNA(Sec) selenium transferase; selenocysteine synthase; selenocysteinyl-tRNA(Sec) synthase; catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 789228 selA 3430140 selA Haemophilus influenzae 86-028NP selenocysteine synthase YP_248396.1 787843 D 281310 CDS YP_248397.1 68249285 3430141 789225..791084 1 NC_007146.2 SelB translation factor; Similar to: HI0709, SELB_HAEIN; selenocysteine-specific elongation factor 791084 selB 3430141 selB Haemophilus influenzae 86-028NP selenocysteine-specific elongation factor YP_248397.1 789225 D 281310 CDS YP_248398.1 68249286 3430142 791103..791957 1 NC_007146.2 hypothetical protein 791957 3430142 NTHI0837 Haemophilus influenzae 86-028NP hypothetical protein YP_248398.1 791103 D 281310 CDS YP_248399.1 68249287 3430143 792077..792373 1 NC_007146.2 Similar to: HI0710, Y710_HAEIN; DNA-damage-inducible protein J, negative regulator of translation 792373 relB 3430143 relB Haemophilus influenzae 86-028NP DNA-damage-inducible protein J, negative regulator of translation YP_248399.1 792077 D 281310 CDS YP_248400.1 68249288 3430144 792373..792681 1 NC_007146.2 Similar to: HI0711, YAFQ_HAEIN; hypothetical protein 792681 3430144 NTHI0839 Haemophilus influenzae 86-028NP hypothetical protein YP_248400.1 792373 D 281310 CDS YP_248401.1 68249289 3430146 796227..797525 1 NC_007146.2 TF; Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 797525 tig 3430146 tig Haemophilus influenzae 86-028NP trigger factor YP_248401.1 796227 D 281310 CDS YP_248402.1 68249290 3430147 797648..798229 1 NC_007146.2 endopeptidase Clp; hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 798229 clpP 3430147 clpP Haemophilus influenzae 86-028NP ATP-dependent Clp protease proteolytic subunit YP_248402.1 797648 D 281310 CDS YP_248403.1 68249291 3430148 798239..799474 1 NC_007146.2 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 799474 clpX 3430148 clpX Haemophilus influenzae 86-028NP ATP-dependent protease ATP-binding subunit ClpX YP_248403.1 798239 D 281310 CDS YP_248404.1 68249292 3430149 799619..800035 1 NC_007146.2 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 800035 secE 3430149 secE Haemophilus influenzae 86-028NP preprotein translocase subunit SecE YP_248404.1 799619 D 281310 CDS YP_248405.1 68249293 3430150 800037..800594 1 NC_007146.2 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 800594 nusG 3430150 nusG Haemophilus influenzae 86-028NP transcription antitermination protein NusG YP_248405.1 800037 D 281310 CDS YP_248406.1 68249294 3430151 800745..801497 1 NC_007146.2 Similar to: HI0718, VACJ_HAEIN; VacJ lipoprotein 801497 vacJ 3430151 vacJ Haemophilus influenzae 86-028NP VacJ lipoprotein YP_248406.1 800745 D 281310 CDS YP_248407.1 68249295 3430152 801551..801943 1 NC_007146.2 Similar to: HI0719, YJGF_HAEIN; YjgF family translation initiation inhibitor 801943 3430152 NTHI0851 Haemophilus influenzae 86-028NP YjgF family translation initiation inhibitor YP_248407.1 801551 D 281310 CDS YP_248408.1 68249296 3430153 802111..802962 1 NC_007146.2 metalloprotease; heat shock protein HtpX 802962 htpX 3430153 htpX Haemophilus influenzae 86-028NP heat shock protein HtpX YP_248408.1 802111 D 281310 CDS YP_248409.2 161761277 3430154 complement(803004..803243) 1 NC_007146.2 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 803243 sirA 3430154 sirA Haemophilus influenzae 86-028NP sulfur transfer protein SirA YP_248409.2 803004 R 281310 CDS YP_248410.1 68249298 3430155 803359..803979 1 NC_007146.2 Similar to: HI0722, YIGZ_HAEIN; hypothetical protein 803979 3430155 NTHI0854 Haemophilus influenzae 86-028NP hypothetical protein YP_248410.1 803359 D 281310 CDS YP_248411.1 68249299 3430156 803982..805445 1 NC_007146.2 Similar to: HI0723, TRKH_HAEIN; Trk system potassium uptake protein TrkH 805445 trkH 3430156 trkH Haemophilus influenzae 86-028NP Trk system potassium uptake protein TrkH YP_248411.1 803982 D 281310 CDS YP_248412.1 68249300 3430164 811880..812299 1 NC_007146.2 phosphate-starvation-inducible protein PsiE 812299 psiE 3430164 psiE Haemophilus influenzae 86-028NP phosphate-starvation-inducible protein PsiE YP_248412.1 811880 D 281310 CDS YP_248413.1 68249301 3430165 complement(812363..813649) 1 NC_007146.2 Similar to: HI0602, HEMY_HAEIN; HemY 813649 hemY 3430165 hemY Haemophilus influenzae 86-028NP HemY YP_248413.1 812363 R 281310 CDS YP_248414.1 68249302 3430166 complement(813660..814871) 1 NC_007146.2 Similar to: HI0603, Y603_HAEIN; uroporphyrin-III C-methyltransferase 814871 hemX 3430166 hemX Haemophilus influenzae 86-028NP uroporphyrin-III C-methyltransferase YP_248414.1 813660 R 281310 CDS YP_248415.1 68249303 3430167 815177..817708 1 NC_007146.2 ATP pyrophosphate-lyase; adenylyl cyclase; catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 817708 cyaA 3430167 cyaA Haemophilus influenzae 86-028NP adenylate cyclase YP_248415.1 815177 D 281310 CDS YP_248416.1 68249304 3430168 817782..818789 1 NC_007146.2 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 818789 gpsA 3430168 gpsA Haemophilus influenzae 86-028NP NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_248416.1 817782 D 281310 CDS YP_248417.1 68249305 3430169 818806..819609 1 NC_007146.2 SAT; catalyzes the O-acetylation of serine; serine acetyltransferase 819609 cysE 3430169 cysE Haemophilus influenzae 86-028NP serine acetyltransferase YP_248417.1 818806 D 281310 CDS YP_248418.1 68249306 3430170 819619..820434 1 NC_007146.2 catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 820434 aroE 3430170 aroE Haemophilus influenzae 86-028NP shikimate 5-dehydrogenase YP_248418.1 819619 D 281310 CDS YP_248419.1 68249307 3430171 820572..821957 1 NC_007146.2 Similar to: HI0608, Y608_HAEIN; di- and tricarboxylate transporter 821957 3430171 NTHI0863 Haemophilus influenzae 86-028NP di- and tricarboxylate transporter YP_248419.1 820572 D 281310 CDS YP_248420.1 68249308 3430172 complement(822095..822943) 1 NC_007146.2 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 822943 folD 3430172 folD Haemophilus influenzae 86-028NP bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_248420.1 822095 R 281310 CDS YP_248421.1 68249309 3430175 complement(823471..824757) 1 NC_007146.2 Similar to: HI0610, FUCP_HAEIN; L-fucose permease 824757 fucP 3430175 fucP Haemophilus influenzae 86-028NP L-fucose permease YP_248421.1 823471 R 281310 CDS YP_248422.1 68249310 3430176 complement(824796..825446) 1 NC_007146.2 L-fuculose-1-phosphate aldolase; catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 825446 fucA 3430176 fucA Haemophilus influenzae 86-028NP L-fuculose phosphate aldolase YP_248422.1 824796 R 281310 CDS YP_248423.1 68249311 3430177 complement(825466..825900) 1 NC_007146.2 Similar to: HI0612, FUCU_HAEIN; fucose operon protein FucU 825900 fucU 3430177 fucU Haemophilus influenzae 86-028NP fucose operon protein FucU YP_248423.1 825466 R 281310 CDS YP_248424.1 68249312 3430178 complement(825914..827326) 1 NC_007146.2 L-fuculose kinase; Similar to: HI0613, FUCK_HAEIN; L-fuculokinase 827326 fucK 3430178 fucK Haemophilus influenzae 86-028NP L-fuculokinase YP_248424.1 825914 R 281310 CDS YP_248425.2 161761276 3430179 complement(827399..829168) 1 NC_007146.2 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 829168 fucI 3430179 fucI Haemophilus influenzae 86-028NP L-fucose isomerase YP_248425.2 827399 R 281310 CDS YP_248426.1 68249314 3430180 complement(829398..830147) 1 NC_007146.2 Similar to: HI0615, FUCR_HAEIN; L-fucose operon activator 830147 fucR 3430180 fucR Haemophilus influenzae 86-028NP L-fucose operon activator YP_248426.1 829398 R 281310 CDS YP_248427.1 68249315 3430181 830346..833117 1 NC_007146.2 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 833117 hepA 3430181 hepA Haemophilus influenzae 86-028NP ATP-dependent helicase HepA YP_248427.1 830346 D 281310 CDS YP_248428.1 68249316 3430182 833120..833779 1 NC_007146.2 pseudouridylate synthase; uracil hydrolyase; Similar to: HI0617, RLUA_HAEIN; pseudouridylate synthase 833779 rluA 3430182 rluA Haemophilus influenzae 86-028NP pseudouridylate synthase YP_248428.1 833120 D 281310 CDS YP_248429.1 68249317 3430183 833806..834384 1 NC_007146.2 Similar to: HI0618, GLPG_HAEIN; hypothetical protein 834384 glpG 3430183 glpG Haemophilus influenzae 86-028NP hypothetical protein YP_248429.1 833806 D 281310 CDS YP_248430.1 68249318 3430184 834414..835181 1 NC_007146.2 Similar to: HI0619, GLPR_HAEIN; glycerol-3-phosphate regulon repressor 835181 glpR 3430184 glpR Haemophilus influenzae 86-028NP glycerol-3-phosphate regulon repressor YP_248430.1 834414 D 281310 CDS YP_248431.1 68249319 3430185 complement(835483..836304) 1 NC_007146.2 Similar to: HI0620, METQ_HAEIN; D-methionine-binding lipoprotein MetQ 836304 metQ 3430185 metQ Haemophilus influenzae 86-028NP D-methionine-binding lipoprotein MetQ YP_248431.1 835483 R 281310 CDS YP_248432.1 68249320 3430186 complement(836343..837032) 1 NC_007146.2 Similar to: METI_HAEIN; D-methionine transport system permease protein 837032 metI 3430186 metI Haemophilus influenzae 86-028NP D-methionine transport system permease protein YP_248432.1 836343 R 281310 CDS YP_248433.1 68249321 3430187 complement(837022..838059) 1 NC_007146.2 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 838059 metN 3430187 metN Haemophilus influenzae 86-028NP DL-methionine transporter ATP-binding subunit YP_248433.1 837022 R 281310 CDS YP_248434.1 68249322 3430188 838235..838789 1 NC_007146.2 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 838789 3430188 NTHI0880 Haemophilus influenzae 86-028NP D,D-heptose 1,7-bisphosphate phosphatase YP_248434.1 838235 D 281310 CDS YP_248435.1 68249323 3430194 845041..845601 1 NC_007146.2 Similar to: HI0724, Y724_HAEIN; hypothetical protein 845601 3430194 NTHI0881 Haemophilus influenzae 86-028NP hypothetical protein YP_248435.1 845041 D 281310 CDS YP_248436.1 68249324 3430195 845605..846045 1 NC_007146.2 Similar to: HI0725, Y725_HAEIN; hypothetical protein 846045 3430195 NTHI0882 Haemophilus influenzae 86-028NP hypothetical protein YP_248436.1 845605 D 281310 CDS YP_248437.1 68249325 3430196 complement(846107..846733) 1 NC_007146.2 Similar to: HI0726, NARP_HAEIN; nitrate/nitrite response regulator protein 846733 narP 3430196 narP Haemophilus influenzae 86-028NP nitrate/nitrite response regulator protein YP_248437.1 846107 R 281310 CDS YP_248438.1 68249326 3430197 complement(846939..848186) 1 NC_007146.2 DAP decarboxylase; Similar to: HI0727, DCDA_HAEIN; diaminopimelate decarboxylase 848186 lysA 3430197 lysA Haemophilus influenzae 86-028NP diaminopimelate decarboxylase YP_248438.1 846939 R 281310 CDS YP_248439.1 68249327 3430198 complement(848234..848365) 1 NC_007146.2 hypothetical protein 848365 3430198 NTHI0885 Haemophilus influenzae 86-028NP hypothetical protein YP_248439.1 848234 R 281310 CDS YP_248440.1 68249328 3430199 848448..848753 1 NC_007146.2 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 848753 cyaY 3430199 cyaY Haemophilus influenzae 86-028NP frataxin-like protein YP_248440.1 848448 D 281310 CDS YP_248441.1 68249329 3430200 848755..850614 1 NC_007146.2 Similar to: HI0728, RECQ_HAEIN; ATP-dependent DNA helicase RecQ 850614 recQ 3430200 recQ Haemophilus influenzae 86-028NP ATP-dependent DNA helicase RecQ YP_248441.1 848755 D 281310 CDS YP_248442.1 68249330 3430201 850699..852417 1 NC_007146.2 proline--tRNA ligase; ProRS; catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 852417 proS 3430201 proS Haemophilus influenzae 86-028NP prolyl-tRNA synthetase YP_248442.1 850699 D 281310 CDS YP_248443.1 68249331 3430202 complement(852505..854853) 1 NC_007146.2 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 854853 ostA 3430202 ostA Haemophilus influenzae 86-028NP organic solvent tolerance protein YP_248443.1 852505 R 281310 CDS YP_248444.1 68249332 3430203 complement(854976..856385) 1 NC_007146.2 Similar to: HI0733, SUFI_HAEIN; hypothetical protein 856385 sufI 3430203 sufI Haemophilus influenzae 86-028NP hypothetical protein YP_248444.1 854976 R 281310 CDS YP_248445.1 68249333 3430204 complement(856387..857109) 1 NC_007146.2 1-AGP acyltransferase; 1-AGPAT; lysophosphatidic acid acyltransferase; LPAAT; Similar to: HI0734, PLSC_HAEIN; 1-acyl-sn-glycerol-3-phosphate acyltransferase 857109 plsC 3430204 plsC Haemophilus influenzae 86-028NP 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_248445.1 856387 R 281310 CDS YP_248446.1 68249334 3430205 857195..857908 1 NC_007146.2 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 857908 lpxH 3430205 lpxH Haemophilus influenzae 86-028NP UDP-2,3-diacylglucosamine hydrolase YP_248446.1 857195 D 281310 CDS YP_248447.1 68249335 3430206 complement(858138..859664) 1 NC_007146.2 Similar to: HI0736, Y736_HAEIN; sodium-dependent transporter 859664 3430206 NTHI0893 Haemophilus influenzae 86-028NP sodium-dependent transporter YP_248447.1 858138 R 281310 CDS YP_248448.1 68249336 3430207 859911..860537 1 NC_007146.2 Similar to: HI0737, Y737_HAEIN; acetolactate synthase isozyme II large subunit 860537 ilvG 3430207 ilvG Haemophilus influenzae 86-028NP acetolactate synthase isozyme II large subunit YP_248448.1 859911 D 281310 CDS YP_248449.1 68249337 3430208 860579..862417 1 NC_007146.2 DAD; catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 862417 ilvD 3430208 ilvD Haemophilus influenzae 86-028NP dihydroxy-acid dehydratase YP_248449.1 860579 D 281310 CDS YP_248450.1 68249338 3430209 862497..864038 1 NC_007146.2 threonine deaminase; threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 864038 thd1 3430209 thd1 Haemophilus influenzae 86-028NP threonine dehydratase YP_248450.1 862497 D 281310 CDS YP_248451.1 68249339 3430210 complement(864076..867555) 1 NC_007146.2 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 867555 dnaE 3430210 dnaE Haemophilus influenzae 86-028NP DNA polymerase III subunit alpha YP_248451.1 864076 R 281310 CDS YP_248452.1 68249340 3430211 867794..869437 1 NC_007146.2 Similar to: HI0740, Y740_HAEIN; phosphoglucomutase 869437 pgmB 3430211 pgmB Haemophilus influenzae 86-028NP phosphoglucomutase YP_248452.1 867794 D 281310 CDS YP_248453.1 68249341 3430212 complement(869604..870113) 1 NC_007146.2 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 870113 secB 3430212 secB Haemophilus influenzae 86-028NP preprotein translocase subunit SecB YP_248453.1 869604 R 281310 CDS YP_248454.1 68249342 3430213 complement(870127..870573) 1 NC_007146.2 Similar to: HI0744, YIBN_HAEIN; rhodanese-related sulfurtransferase 870573 3430213 NTHI0901 Haemophilus influenzae 86-028NP rhodanese-related sulfurtransferase YP_248454.1 870127 R 281310 CDS YP_248455.1 68249343 3430214 870821..872143 1 NC_007146.2 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 872143 dcuB 3430214 dcuB Haemophilus influenzae 86-028NP anaerobic C4-dicarboxylate transporter YP_248455.1 870821 D 281310 CDS YP_248456.1 68249344 3430215 872347..873681 1 NC_007146.2 Similar to: HI0747, DHNA_HAEIN; NADH dehydrogenase 873681 ndhA 3430215 ndhA Haemophilus influenzae 86-028NP NADH dehydrogenase YP_248456.1 872347 D 281310 CDS YP_248457.1 68249345 3430216 complement(873761..876193) 1 NC_007146.2 GPAT; PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 876193 plsB 3430216 plsB Haemophilus influenzae 86-028NP glycerol-3-phosphate acyltransferase YP_248457.1 873761 R 281310 CDS YP_248458.1 68249346 3430217 876442..877071 1 NC_007146.2 Represses a number of genes involved in the response to DNA damage; LexA repressor 877071 lexA 3430217 lexA Haemophilus influenzae 86-028NP LexA repressor YP_248458.1 876442 D 281310 CDS YP_248459.1 68249347 3430218 877214..878038 1 NC_007146.2 DAP epimerase; involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 878038 dapF 3430218 dapF Haemophilus influenzae 86-028NP diaminopimelate epimerase YP_248459.1 877214 D 281310 CDS YP_248460.1 68249348 3430219 complement(878258..878755) 1 NC_007146.2 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 878755 tpx 3430219 tpx Haemophilus influenzae 86-028NP thiol peroxidase YP_248460.1 878258 R 281310 CDS YP_248461.1 68249349 3430220 879318..883280 1 NC_007146.2 FGAM synthase; formylglycinamide ribotide amidotransferase; FGARAT; catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 883280 purL 3430220 purL Haemophilus influenzae 86-028NP phosphoribosylformylglycinamidine synthase YP_248461.1 879318 D 281310 CDS YP_248462.1 68249350 3430222 883786..884529 1 NC_007146.2 UDP-glucose--lipooligosaccharide glucosyltransferase 884529 lex2B 3430222 lex2B Haemophilus influenzae 86-028NP UDP-glucose--lipooligosaccharide glucosyltransferase YP_248462.1 883786 D 281310 CDS YP_248463.1 68249351 3430223 complement(884590..885432) 1 NC_007146.2 Similar to: HI0755, YIBQ_HAEIN; hypothetical protein 885432 3430223 NTHI0914 Haemophilus influenzae 86-028NP hypothetical protein YP_248463.1 884590 R 281310 CDS YP_248464.1 68249352 3430224 complement(885432..886664) 1 NC_007146.2 Similar to: HI0756, YIBP_HAEIN; membrane-bound metallopeptidase 886664 3430224 NTHI0915 Haemophilus influenzae 86-028NP membrane-bound metallopeptidase YP_248464.1 885432 R 281310 CDS YP_248465.1 68249353 3430225 886840..887523 1 NC_007146.2 phosphoglyceromutase; PGAM; BPG-dependent PGAM; dPGM; 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 887523 gpmA 3430225 gpmA Haemophilus influenzae 86-028NP phosphoglyceromutase YP_248465.1 886840 D 281310 CDS YP_248466.1 68249354 3430226 complement(887601..887813) 1 NC_007146.2 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 887813 rpmE 3430226 rpmE Haemophilus influenzae 86-028NP 50S ribosomal protein L31 YP_248466.1 887601 R 281310 CDS YP_248467.1 68249355 3430227 887990..889126 1 NC_007146.2 Similar to: HI0759, MUTY_HAEIN; A/G-specific adenine glycosylase 889126 mutY 3430227 mutY Haemophilus influenzae 86-028NP A/G-specific adenine glycosylase YP_248467.1 887990 D 281310 CDS YP_248468.1 68249356 3430228 889104..889376 1 NC_007146.2 Similar to: HI0760, Y760_HAEIN; hypothetical protein 889376 3430228 NTHI0920 Haemophilus influenzae 86-028NP hypothetical protein YP_248468.1 889104 D 281310 CDS YP_248469.1 68249357 3430229 889391..890464 1 NC_007146.2 Murein hydrolase C; Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 890464 mltC 3430229 mltC Haemophilus influenzae 86-028NP murein transglycosylase C YP_248469.1 889391 D 281310 CDS YP_248470.1 68249358 3430232 complement(891075..891755) 1 NC_007146.2 Similar to: HI0762, Y762_HAEIN; diadenosine tetraphosphatase and related serine/threonine protein phosphatase 891755 3430232 NTHI0922 Haemophilus influenzae 86-028NP diadenosine tetraphosphatase and related serine/threonine protein phosphatase YP_248470.1 891075 R 281310 CDS YP_248471.1 68249359 3430233 complement(891752..893017) 1 NC_007146.2 NMN adenylyltransferase; ribosylnicotinamide kinase; NMNAT; RNK; catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 893017 nadR 3430233 nadR Haemophilus influenzae 86-028NP nicotinamide-nucleotide adenylyltransferase YP_248471.1 891752 R 281310 CDS YP_248472.1 68249360 3430234 893236..893883 1 NC_007146.2 DHBP synthase; DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 893883 ribB 3430234 ribB Haemophilus influenzae 86-028NP 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_248472.1 893236 D 281310 CDS YP_248473.1 68249361 3430235 893898..894746 1 NC_007146.2 Similar to: HI0765, Y765_HAEIN; lipooligosaccharide glycosyl transferase 894746 lpsA 3430235 lpsA Haemophilus influenzae 86-028NP lipooligosaccharide glycosyl transferase YP_248473.1 893898 D 281310 CDS YP_248474.1 68249362 3430236 complement(894795..895277) 1 NC_007146.2 Similar to: HI0766, YIBK_HAEIN; RNA methyltransferase 895277 3430236 NTHI0927 Haemophilus influenzae 86-028NP RNA methyltransferase YP_248474.1 894795 R 281310 CDS YP_248475.1 68249363 3430237 complement(895287..895868) 1 NC_007146.2 Similar to: HI0767, YHHF_HAEIN; hypothetical protein 895868 3430237 NTHI0928 Haemophilus influenzae 86-028NP hypothetical protein YP_248475.1 895287 R 281310 CDS YP_248476.1 68249364 3430238 895923..897167 1 NC_007146.2 Similar to: HI0768, FTSY_HAEIN; cell division protein FtsY 897167 ftsY 3430238 ftsY Haemophilus influenzae 86-028NP cell division protein FtsY YP_248476.1 895923 D 281310 CDS YP_248477.1 68249365 3430239 897186..897842 1 NC_007146.2 Similar to: HI0769, FTSE_HAEIN; cell division ATP-binding protein FtsE 897842 ftsE 3430239 ftsE Haemophilus influenzae 86-028NP cell division ATP-binding protein FtsE YP_248477.1 897186 D 281310 CDS YP_248478.1 68249366 3430240 897852..898784 1 NC_007146.2 ABC transporter, membrane protein; cell division protein FtsX 898784 ftsX 3430240 ftsX Haemophilus influenzae 86-028NP cell division protein FtsX YP_248478.1 897852 D 281310 CDS YP_248479.1 68249367 3430241 complement(898879..900060) 1 NC_007146.2 acetoacetyl-CoA thiolase; Similar to: HI0771, ATOB_HAEIN; acetyl-CoA acetyltransferase 900060 atoB 3430241 atoB Haemophilus influenzae 86-028NP acetyl-CoA acetyltransferase YP_248479.1 898879 R 281310 CDS YP_248480.1 68249368 3430242 complement(900075..901418) 1 NC_007146.2 Similar to: HI0772, ATOE_HAEIN; short-chain fatty acids transporter 901418 atoE 3430242 atoE Haemophilus influenzae 86-028NP short-chain fatty acids transporter YP_248480.1 900075 R 281310 CDS YP_248481.1 68249369 3430243 complement(901421..902086) 1 NC_007146.2 Acetyl-CoA:acetoacetate CoA transferase beta subunit; Similar to: HI0773, ATOA_HAEIN; acetate CoA-transferase subunit beta 902086 atoA 3430243 atoA Haemophilus influenzae 86-028NP acetate CoA-transferase subunit beta YP_248481.1 901421 R 281310 CDS YP_248482.1 68249370 3430244 complement(902097..902750) 1 NC_007146.2 Acetyl-CoA:acetoacetate CoA transferase alpha subunit; Similar to: HI0774, ATOD_HAEIN; acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 902750 atoD 3430244 atoD Haemophilus influenzae 86-028NP acetyl-CoA:acetoacetyl-CoA transferase subunit alpha YP_248482.1 902097 R 281310 CDS YP_248483.1 68249371 3430245 902956..903903 1 NC_007146.2 Similar to: HI0775, Y775_HAEIN; HTH-type transcriptional regulator 903903 3430245 NTHI0936 Haemophilus influenzae 86-028NP HTH-type transcriptional regulator YP_248483.1 902956 D 281310 CDS YP_248484.1 68249372 3430246 904140..904451 1 NC_007146.2 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 904451 rpsJ 3430246 rpsJ Haemophilus influenzae 86-028NP 30S ribosomal protein S10 YP_248484.1 904140 D 281310 CDS YP_248485.1 68249373 3430247 904468..905094 1 NC_007146.2 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 905094 rplC 3430247 rplC Haemophilus influenzae 86-028NP 50S ribosomal protein L3 YP_248485.1 904468 D 281310 CDS YP_248486.1 68249374 3430248 905110..905712 1 NC_007146.2 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 905712 rplD 3430248 rplD Haemophilus influenzae 86-028NP 50S ribosomal protein L4 YP_248486.1 905110 D 281310 CDS YP_248487.1 68249375 3430249 905709..906008 1 NC_007146.2 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 906008 rplW 3430249 rplW Haemophilus influenzae 86-028NP 50S ribosomal protein L23 YP_248487.1 905709 D 281310 CDS YP_248488.1 68249376 3430250 906026..906847 1 NC_007146.2 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 906847 rplB 3430250 rplB Haemophilus influenzae 86-028NP 50S ribosomal protein L2 YP_248488.1 906026 D 281310 CDS YP_248489.1 68249377 3430251 906873..907148 1 NC_007146.2 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 907148 rpsS 3430251 rpsS Haemophilus influenzae 86-028NP 30S ribosomal protein S19 YP_248489.1 906873 D 281310 CDS YP_248490.1 68249378 3430252 907160..907492 1 NC_007146.2 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 907492 rplV 3430252 rplV Haemophilus influenzae 86-028NP 50S ribosomal protein L22 YP_248490.1 907160 D 281310 CDS YP_248491.1 68249379 3430253 907510..908217 1 NC_007146.2 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 908217 rpsC 3430253 rpsC Haemophilus influenzae 86-028NP 30S ribosomal protein S3 YP_248491.1 907510 D 281310 CDS YP_248492.1 68249380 3430254 908231..908641 1 NC_007146.2 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 908641 rplP 3430254 rplP Haemophilus influenzae 86-028NP 50S ribosomal protein L16 YP_248492.1 908231 D 281310 CDS YP_248493.1 68249381 3430255 908641..908832 1 NC_007146.2 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 908832 rpmC 3430255 rpmC Haemophilus influenzae 86-028NP 50S ribosomal protein L29 YP_248493.1 908641 D 281310 CDS YP_248494.1 68249382 3430256 908832..909089 1 NC_007146.2 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 909089 rpsQ 3430256 rpsQ Haemophilus influenzae 86-028NP 30S ribosomal protein S17 YP_248494.1 908832 D 281310 CDS YP_248495.1 68249383 3430257 909479..910102 1 NC_007146.2 Similar to: HI0787, Y787_HAEIN; hypothetical protein 910102 3430257 NTHI0950 Haemophilus influenzae 86-028NP hypothetical protein YP_248495.1 909479 D 281310 CDS YP_248496.1 68249384 3430258 910383..910754 1 NC_007146.2 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 910754 rplN 3430258 rplN Haemophilus influenzae 86-028NP 50S ribosomal protein L14 YP_248496.1 910383 D 281310 CDS YP_248497.1 68249385 3430259 910765..911076 1 NC_007146.2 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 911076 rplX 3430259 rplX Haemophilus influenzae 86-028NP 50S ribosomal protein L24 YP_248497.1 910765 D 281310 CDS YP_248498.1 68249386 3430260 911094..911633 1 NC_007146.2 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 911633 rplE 3430260 rplE Haemophilus influenzae 86-028NP 50S ribosomal protein L5 YP_248498.1 911094 D 281310 CDS YP_248499.1 68249387 3430261 911645..911950 1 NC_007146.2 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 911950 rpsN 3430261 rpsN Haemophilus influenzae 86-028NP 30S ribosomal protein S14 YP_248499.1 911645 D 281310 CDS YP_248500.1 68249388 3430262 911987..912379 1 NC_007146.2 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 912379 rpsH 3430262 rpsH Haemophilus influenzae 86-028NP 30S ribosomal protein S8 YP_248500.1 911987 D 281310 CDS YP_248501.1 68249389 3430263 912395..912928 1 NC_007146.2 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 912928 rplF 3430263 rplF Haemophilus influenzae 86-028NP 50S ribosomal protein L6 YP_248501.1 912395 D 281310 CDS YP_248502.1 68249390 3430264 912942..913295 1 NC_007146.2 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 913295 rplR 3430264 rplR Haemophilus influenzae 86-028NP 50S ribosomal protein L18 YP_248502.1 912942 D 281310 CDS YP_248503.1 68249391 3430265 913310..913810 1 NC_007146.2 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 913810 rpsE 3430265 rpsE Haemophilus influenzae 86-028NP 30S ribosomal protein S5 YP_248503.1 913310 D 281310 CDS YP_248504.1 68249392 3430266 913817..913996 1 NC_007146.2 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 913996 rpmD 3430266 rpmD Haemophilus influenzae 86-028NP 50S ribosomal protein L30 YP_248504.1 913817 D 281310 CDS YP_248505.1 68249393 3430267 914000..914434 1 NC_007146.2 late assembly protein; 50S ribosomal protein L15 914434 rplO 3430267 rplO Haemophilus influenzae 86-028NP 50S ribosomal protein L15 YP_248505.1 914000 D 281310 CDS YP_248506.1 68249394 3430268 914442..915767 1 NC_007146.2 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 915767 secY 3430268 secY Haemophilus influenzae 86-028NP preprotein translocase subunit SecY YP_248506.1 914442 D 281310 CDS YP_248507.1 68249395 3430269 916049..916405 1 NC_007146.2 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 916405 rpsM 3430269 rpsM Haemophilus influenzae 86-028NP 30S ribosomal protein S13 YP_248507.1 916049 D 281310 CDS YP_248508.1 68249396 3430270 916421..916810 1 NC_007146.2 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 916810 rpsK 3430270 rpsK Haemophilus influenzae 86-028NP 30S ribosomal protein S11 YP_248508.1 916421 D 281310 CDS YP_248509.1 68249397 3430271 916838..917458 1 NC_007146.2 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 917458 rpsD 3430271 rpsD Haemophilus influenzae 86-028NP 30S ribosomal protein S4 YP_248509.1 916838 D 281310 CDS YP_248510.1 68249398 3430272 917490..918476 1 NC_007146.2 RNAP alpha subunit; transcriptase alpha chain; RNA polymerase alpha subunit; catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 918476 rpoA 3430272 rpoA Haemophilus influenzae 86-028NP DNA-directed RNA polymerase subunit alpha YP_248510.1 917490 D 281310 CDS YP_248511.1 68249399 3430273 918517..918903 1 NC_007146.2 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 918903 rplQ 3430273 rplQ Haemophilus influenzae 86-028NP 50S ribosomal protein L17 YP_248511.1 918517 D 281310 CDS YP_248512.1 68249400 3430274 complement(919030..919626) 1 NC_007146.2 Similar to: HI0804, Y804_HAEIN; cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase 919626 3430274 NTHI0967 Haemophilus influenzae 86-028NP cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase YP_248512.1 919030 R 281310 CDS YP_248513.1 68249401 3430276 920579..921388 1 NC_007146.2 Similar to: HI0806, Y806_HAEIN; permease 921388 3430276 NTHI0970 Haemophilus influenzae 86-028NP permease YP_248513.1 920579 D 281310 CDS YP_248514.1 68249402 3430277 complement(921420..922613) 1 NC_007146.2 DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 922613 dxr 3430277 dxr Haemophilus influenzae 86-028NP 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_248514.1 921420 R 281310 CDS YP_248515.1 68249403 3430278 complement(922723..923280) 1 NC_007146.2 ribosome releasing factor; RRF; Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 923280 frr 3430278 frr Haemophilus influenzae 86-028NP ribosome recycling factor YP_248515.1 922723 R 281310 CDS YP_248516.1 68249404 3430279 complement(923432..925048) 1 NC_007146.2 PEP carboxykinase; phosphoenolpyruvate carboxylase; PEPCK; PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 925048 pckA 3430279 pckA Haemophilus influenzae 86-028NP phosphoenolpyruvate carboxykinase YP_248516.1 923432 R 281310 CDS YP_248517.1 68249405 3430280 complement(925221..926102) 1 NC_007146.2 Heat shock protein 33 homolog; HSP33; becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 926102 hslO 3430280 hslO Haemophilus influenzae 86-028NP heat shock protein 33 YP_248517.1 925221 R 281310 CDS YP_248518.1 68249406 3430281 complement(926247..927620) 1 NC_007146.2 arginosuccinase; ASAL; catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 927620 argH 3430281 argH Haemophilus influenzae 86-028NP argininosuccinate lyase YP_248518.1 926247 R 281310 CDS YP_248519.1 68249407 3430282 complement(927755..928642) 1 NC_007146.2 UDP-glucose pyrophosphorylase; UDPGP; Alpha-D-glucosyl-1-phosphate uridylyltransferase; uridine diphosphoglucose pyrophosphorylase; Similar to: HI0812, GALU_HAEIN; UTP-glucose-1-phosphate uridylyltransferase 928642 galU 3430282 galU Haemophilus influenzae 86-028NP UTP-glucose-1-phosphate uridylyltransferase YP_248519.1 927755 R 281310 CDS YP_248520.1 68249408 3430283 complement(928664..928855) 1 NC_007146.2 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 928855 csrA 3430283 csrA Haemophilus influenzae 86-028NP carbon storage regulator YP_248520.1 928664 R 281310 CDS YP_248521.1 68249409 3430284 complement(928933..931557) 1 NC_007146.2 alanine--tRNA ligase; AlaRS; Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 931557 alaS 3430284 alaS Haemophilus influenzae 86-028NP alanyl-tRNA synthetase YP_248521.1 928933 R 281310 CDS YP_248522.1 68249410 3430285 complement(931744..932169) 1 NC_007146.2 Similar to: HI0815, USPA_HAEIN; universal stress protein A 932169 uspA 3430285 uspA Haemophilus influenzae 86-028NP universal stress protein A YP_248522.1 931744 R 281310 CDS YP_248523.1 68249411 3430286 complement(932271..933563) 1 NC_007146.2 X-Pro aminopeptidase; aminopeptidase P II; APP-II; aminoacylproline aminopeptidase; Similar to: HI0816, AMPP_HAEIN; Xaa-Pro aminopeptidase 933563 pepP 3430286 pepP Haemophilus influenzae 86-028NP Xaa-Pro aminopeptidase YP_248523.1 932271 R 281310 CDS YP_248524.1 68249412 3430287 complement(933575..934123) 1 NC_007146.2 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 934123 3430287 NTHI0981 Haemophilus influenzae 86-028NP hypothetical protein YP_248524.1 933575 R 281310 CDS YP_248525.1 68249413 3430288 complement(934294..935319) 1 NC_007146.2 mutarotase; catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 935319 galM 3430288 galM Haemophilus influenzae 86-028NP aldose 1-epimerase YP_248525.1 934294 R 281310 CDS YP_248526.1 68249414 3430289 complement(935326..936522) 1 NC_007146.2 galactose kinase; catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 936522 galK 3430289 galK Haemophilus influenzae 86-028NP galactokinase YP_248526.1 935326 R 281310 CDS YP_248527.1 68249415 3430290 complement(936557..937606) 1 NC_007146.2 Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase; catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 937606 galT 3430290 galT Haemophilus influenzae 86-028NP galactose-1-phosphate uridylyltransferase YP_248527.1 936557 R 281310 CDS YP_248528.1 68249416 3430291 937814..938812 1 NC_007146.2 galactose operon repressor; Similar to: HI0821, GALR_HAEIN; HTH-type transcriptional regulator GalR 938812 galR 3430291 galR Haemophilus influenzae 86-028NP HTH-type transcriptional regulator GalR YP_248528.1 937814 D 281310 CDS YP_248529.1 68249417 3430292 938903..939952 1 NC_007146.2 GBP; D-galactose/ D-glucose binding protein; GGBP; Similar to: HI0822, DGAL_HAEIN; D-galactose-binding periplasmic protein 939952 mglB 3430292 mglB Haemophilus influenzae 86-028NP D-galactose-binding periplasmic protein YP_248529.1 938903 D 281310 CDS YP_248530.1 68249418 3430293 940018..941538 1 NC_007146.2 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 941538 mglA 3430293 mglA Haemophilus influenzae 86-028NP galactose/methyl galaxtoside transporter ATP-binding protein YP_248530.1 940018 D 281310 CDS YP_248531.1 68249419 3430294 941555..942565 1 NC_007146.2 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane component 942565 mglC 3430294 mglC Haemophilus influenzae 86-028NP beta-methylgalactoside transporter inner membrane component YP_248531.1 941555 D 281310 CDS YP_248532.1 68249420 3430295 942711..943445 1 NC_007146.2 Similar to: HI0825, Y825_HAEIN; hypothetical protein 943445 3430295 NTHI0990 Haemophilus influenzae 86-028NP hypothetical protein YP_248532.1 942711 D 281310 CDS YP_248533.1 68249421 3430296 943451..944008 1 NC_007146.2 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 944008 ispZ 3430296 ispZ Haemophilus influenzae 86-028NP intracellular septation protein A YP_248533.1 943451 D 281310 CDS YP_248534.1 68249422 3430297 944008..944472 1 NC_007146.2 Similar to: HI0827, YCIA_HAEIN; acyl-CoA thioester hydrolase 944472 3430297 NTHI0992 Haemophilus influenzae 86-028NP acyl-CoA thioester hydrolase YP_248534.1 944008 D 281310 CDS YP_248535.1 68249423 3430298 944489..944785 1 NC_007146.2 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein 944785 3430298 NTHI0994 Haemophilus influenzae 86-028NP hypothetical protein YP_248535.1 944489 D 281310 CDS YP_248536.1 68249424 3430299 944801..946582 1 NC_007146.2 Similar to: HI0829, SLT_HAEIN; soluble lytic murein transglycosylase 946582 slt 3430299 slt Haemophilus influenzae 86-028NP soluble lytic murein transglycosylase YP_248536.1 944801 D 281310 CDS YP_248537.1 68249425 3430300 946620..946925 1 NC_007146.2 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 946925 trpR 3430300 trpR Haemophilus influenzae 86-028NP Trp operon repressor YP_248537.1 946620 D 281310 CDS YP_248538.2 161761275 3430301 946912..947652 1 NC_007146.2 monofunctional TGase; glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 947652 mtgA 3430301 mtgA Haemophilus influenzae 86-028NP monofunctional biosynthetic peptidoglycan transglycosylase YP_248538.2 946912 D 281310 CDS YP_248539.1 68249427 3430302 complement(947758..948102) 1 NC_007146.2 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 948102 frdD 3430302 frdD Haemophilus influenzae 86-028NP fumarate reductase subunit D YP_248539.1 947758 R 281310 CDS YP_248540.1 68249428 3430303 complement(948115..948525) 1 NC_007146.2 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 948525 frdC 3430303 frdC Haemophilus influenzae 86-028NP fumarate reductase subunit C YP_248540.1 948115 R 281310 CDS YP_248541.1 68249429 3430304 complement(948536..949306) 1 NC_007146.2 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 949306 frdB 3430304 frdB Haemophilus influenzae 86-028NP fumarate reductase iron-sulfur subunit YP_248541.1 948536 R 281310 CDS YP_248542.1 68249430 3430305 complement(949299..951098) 1 NC_007146.2 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 951098 frdA 3430305 frdA Haemophilus influenzae 86-028NP fumarate reductase flavoprotein subunit YP_248542.1 949299 R 281310 CDS YP_248543.2 161761274 3430306 951309..952280 1 NC_007146.2 Lysine--tRNA ligase; LysRS; GX; lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 952280 genX 3430306 genX Haemophilus influenzae 86-028NP lysyl-tRNA synthetase YP_248543.2 951309 D 281310 CDS YP_248544.1 68249432 3430307 complement(952546..953229) 1 NC_007146.2 Similar to: HI0837, CPXR_HAEIN; transcriptional regulatory protein CpxR 953229 cpxR 3430307 cpxR Haemophilus influenzae 86-028NP transcriptional regulatory protein CpxR YP_248544.1 952546 R 281310 CDS YP_248545.1 68249433 3430308 complement(953283..953696) 1 NC_007146.2 Similar to: HI0838, SMPA_HAEIN; small protein A 953696 smpA 3430308 smpA Haemophilus influenzae 86-028NP small protein A YP_248545.1 953283 R 281310 CDS YP_248546.1 68249434 3430309 complement(953762..954787) 1 NC_007146.2 Similar to: HI0839, NDPA_HAEIN; nucleoid-associated protein NdpA 954787 ndpA 3430309 ndpA Haemophilus influenzae 86-028NP nucleoid-associated protein NdpA YP_248546.1 953762 R 281310 CDS YP_248547.1 68249435 3430310 954904..955122 1 NC_007146.2 Similar to: HI0840, YEJL_HAEIN; hypothetical protein 955122 3430310 NTHI1007 Haemophilus influenzae 86-028NP hypothetical protein YP_248547.1 954904 D 281310 CDS YP_248548.1 68249436 3430311 955124..956881 1 NC_007146.2 Similar to: HI0841, YEJM_HAEIN; hydrolase of alkaline phosphatase superfamily 956881 3430311 NTHI1008 Haemophilus influenzae 86-028NP hydrolase of alkaline phosphatase superfamily YP_248548.1 955124 D 281310 CDS YP_248549.1 68249437 3430312 957079..958071 1 NC_007146.2 Similar to: HI0842, Y842_HAEIN; hypothetical protein 958071 3430312 NTHI1009 Haemophilus influenzae 86-028NP hypothetical protein YP_248549.1 957079 D 281310 CDS YP_248550.1 68249438 3430313 complement(958210..958788) 1 NC_007146.2 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 958788 mobA 3430313 mobA Haemophilus influenzae 86-028NP molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_248550.1 958210 R 281310 CDS YP_248551.1 68249439 3430314 958853..959119 1 NC_007146.2 Similar to: HI0845, YIHD_HAEIN; hypothetical protein 959119 3430314 NTHI1011 Haemophilus influenzae 86-028NP hypothetical protein YP_248551.1 958853 D 281310 CDS YP_248552.1 68249440 3430315 959130..959747 1 NC_007146.2 Similar to: HI0846, DSBA_HAEIN; thiol:disulfide interchange protein DsbA 959747 dsbA 3430315 dsbA Haemophilus influenzae 86-028NP thiol:disulfide interchange protein DsbA YP_248552.1 959130 D 281310 CDS YP_248553.1 68249441 3430316 959809..960144 1 NC_007146.2 Similar to: HI0847, YIFE_HAEIN; hypothetical protein 960144 3430316 NTHI1013 Haemophilus influenzae 86-028NP hypothetical protein YP_248553.1 959809 D 281310 CDS YP_248554.1 68249442 3430317 960288..961379 1 NC_007146.2 tRNA(M-5-U54)-methyltransferase; RUMT; catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 961379 trmA 3430317 trmA Haemophilus influenzae 86-028NP tRNA (uracil-5-)-methyltransferase YP_248554.1 960288 D 281310 CDS YP_248555.1 68249443 3430318 961568..962134 1 NC_007146.2 Similar to: HI0849, YHIQ_HAEIN; hypothetical protein 962134 3430318 NTHI1015 Haemophilus influenzae 86-028NP hypothetical protein YP_248555.1 961568 D 281310 CDS YP_248556.1 68249444 3430319 962128..962562 1 NC_007146.2 Similar to: HI0850, Y850_HAEIN; positive regulator of sigma E 962562 3430319 NTHI1016 Haemophilus influenzae 86-028NP positive regulator of sigma E YP_248556.1 962128 D 281310 CDS YP_248557.1 68249445 3430320 962963..963499 1 NC_007146.2 Similar to: HI0851, MOBB_HAEIN; molybdopterin-guanine dinucleotide biosynthesis protein B 963499 mobB 3430320 mobB Haemophilus influenzae 86-028NP molybdopterin-guanine dinucleotide biosynthesis protein B YP_248557.1 962963 D 281310 CDS YP_248558.1 68249446 3430321 963496..964887 1 NC_007146.2 Similar to: HI0852, YIEO_HAEIN; hypothetical protein 964887 3430321 NTHI1020 Haemophilus influenzae 86-028NP hypothetical protein YP_248558.1 963496 D 281310 CDS YP_248559.1 68249447 3430322 965028..966677 1 NC_007146.2 hemin-binding lipoprotein; Similar to: HI0853, HBPA_HAEIN; heme-binding protein A 966677 hbpA 3430322 hbpA Haemophilus influenzae 86-028NP heme-binding protein A YP_248559.1 965028 D 281310 CDS YP_248560.1 68249448 3430323 966853..967614 1 NC_007146.2 Similar to: HI0854, Y854_HAEIN; heme iron utilization protein 967614 3430323 NTHI1022 Haemophilus influenzae 86-028NP heme iron utilization protein YP_248560.1 966853 D 281310 CDS YP_248561.1 68249449 3430324 complement(967751..968098) 1 NC_007146.2 Similar to: HI0855, YHAM_HAEIN; hypothetical protein 968098 3430324 NTHI1023 Haemophilus influenzae 86-028NP hypothetical protein YP_248561.1 967751 R 281310 CDS YP_248562.1 68249450 3430325 complement(968113..970905) 1 NC_007146.2 POL I; has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 970905 polA 3430325 polA Haemophilus influenzae 86-028NP DNA polymerase I YP_248562.1 968113 R 281310 CDS YP_248563.1 68249451 3430326 971054..971356 1 NC_007146.2 Similar to: HI0857, YGFE_HAEIN; hypothetical protein 971356 3430326 NTHI1025 Haemophilus influenzae 86-028NP hypothetical protein YP_248563.1 971054 D 281310 CDS YP_248564.1 68249452 3430327 971679..972242 1 NC_007146.2 Similar to: HI0858, YGFA_HAEIN; 5-formyltetrahydrofolate cyclo-ligase 972242 3430327 NTHI1027 Haemophilus influenzae 86-028NP 5-formyltetrahydrofolate cyclo-ligase YP_248564.1 971679 D 281310 CDS YP_248565.1 68249453 3430328 972370..974940 1 NC_007146.2 Similar to: HI0859, CLPB_HAEIN; ClpB 974940 clpB 3430328 clpB Haemophilus influenzae 86-028NP ClpB YP_248565.1 972370 D 281310 CDS YP_248566.1 68249454 3430329 complement(974978..975718) 1 NC_007146.2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 975718 3430329 NTHI1029 Haemophilus influenzae 86-028NP 23S rRNA (guanosine-2'-O-)-methyltransferase YP_248566.1 974978 R 281310 CDS YP_248567.1 68249455 3430330 complement(975774..978122) 1 NC_007146.2 RNase R; VacB; Similar to: HI0861, RNR_HAEIN; ribonuclease R 978122 vacB 3430330 vacB Haemophilus influenzae 86-028NP ribonuclease R YP_248567.1 975774 R 281310 CDS YP_248568.1 68249456 3430331 complement(978314..979021) 1 NC_007146.2 Similar to: HI0862, YHHQ_HAEIN; hypothetical protein 979021 3430331 NTHI1031 Haemophilus influenzae 86-028NP hypothetical protein YP_248568.1 978314 R 281310 CDS YP_248569.2 161761273 3430332 979214..979846 1 NC_007146.2 PNP/PMP oxidase; PNPOx; catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 979846 pdxH 3430332 pdxH Haemophilus influenzae 86-028NP pyridoxamine 5'-phosphate oxidase YP_248569.2 979214 D 281310 CDS YP_248570.1 68249458 3430333 complement(979933..981783) 1 NC_007146.2 Similar to: HI0864, TYPA_HAEIN; GTP-binding protein TypA 981783 typA 3430333 typA Haemophilus influenzae 86-028NP GTP-binding protein TypA YP_248570.1 979933 R 281310 CDS YP_248571.1 68249459 3430334 complement(981910..982890) 1 NC_007146.2 Similar to: HI0352, Y352_HAEIN; CMP-neu5Ac--lipooligosaccharide alpha 2-3 sialyltransferase 982890 lic3A2 3430334 lic3A2 Haemophilus influenzae 86-028NP CMP-neu5Ac--lipooligosaccharide alpha 2-3 sialyltransferase YP_248571.1 981910 R 281310 CDS YP_248572.1 68249460 3430335 983047..984459 1 NC_007146.2 glutamate--ammonia ligase; Similar to: HI0865, GLNA_HAEIN; glutamine synthetase 984459 glnA 3430335 glnA Haemophilus influenzae 86-028NP glutamine synthetase YP_248572.1 983047 D 281310 CDS YP_248573.1 68249461 3430336 984546..985589 1 NC_007146.2 Similar to: HI0873, RFBB_NEIMB; dTDP-glucose 4,6-dehydratase 985589 rmlB 3430336 rmlB Haemophilus influenzae 86-028NP dTDP-glucose 4,6-dehydratase YP_248573.1 984546 D 281310 CDS YP_248574.1 68249462 3430337 985666..986970 1 NC_007146.2 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase 986970 pepB 3430337 pepB Haemophilus influenzae 86-028NP aminopeptidase YP_248574.1 985666 D 281310 CDS YP_248575.1 68249463 3430338 986977..987402 1 NC_007146.2 NDK; NDP kinase; nucleoside-2-P kinase; catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 987402 ndk 3430338 ndk Haemophilus influenzae 86-028NP nucleoside diphosphate kinase YP_248575.1 986977 D 281310 CDS YP_248576.1 68249464 3430339 complement(987472..988644) 1 NC_007146.2 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 988644 obgE 3430339 obgE Haemophilus influenzae 86-028NP GTPase ObgE YP_248576.1 987472 R 281310 CDS YP_248577.1 68249465 3430340 complement(988672..989592) 1 NC_007146.2 Similar to: HI0878, YHBE_HAEIN; transport protein 989592 3430340 NTHI1041 Haemophilus influenzae 86-028NP transport protein YP_248577.1 988672 R 281310 CDS YP_248578.1 68249466 3430341 complement(989672..989929) 1 NC_007146.2 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 989929 rpmA 3430341 rpmA Haemophilus influenzae 86-028NP 50S ribosomal protein L27 YP_248578.1 989672 R 281310 CDS YP_248579.1 68249467 3430342 complement(989950..990261) 1 NC_007146.2 Similar to: HI0880, RL21_HAEIN; 50S ribosomal protein L21 990261 rplU 3430342 rplU Haemophilus influenzae 86-028NP 50S ribosomal protein L21 YP_248579.1 989950 R 281310 CDS YP_248580.1 68249468 3430343 990474..991463 1 NC_007146.2 octaprenyl pyrophosphate synthetase; OPP synthetase; Similar to: HI0881, ISPB_HAEIN; octaprenyl-diphosphate synthase 991463 ispB 3430343 ispB Haemophilus influenzae 86-028NP octaprenyl-diphosphate synthase YP_248580.1 990474 D 281310 CDS YP_248581.1 68249469 3430344 991514..992251 1 NC_007146.2 Similar to: HI0882, Y882_HAEIN; hypothetical protein 992251 3430344 NTHI1045 Haemophilus influenzae 86-028NP hypothetical protein YP_248581.1 991514 D 281310 CDS YP_248582.1 68249470 3430345 complement(992311..993681) 1 NC_007146.2 Similar to: HI0883, Y883_HAEIN; Na+/alanine symporter 993681 3430345 NTHI1046 Haemophilus influenzae 86-028NP Na+/alanine symporter YP_248582.1 992311 R 281310 CDS YP_248583.1 68249471 3430346 complement(994081..994791) 1 NC_007146.2 Similar to: HI0884, ARCA_HAEIN; two-component response regulator 994791 arcA 3430346 arcA Haemophilus influenzae 86-028NP two-component response regulator YP_248583.1 994081 R 281310 CDS YP_248584.1 68249472 3430347 994983..996722 1 NC_007146.2 protein-disulfide reductase; disulfide reductase; C-type cytochrome biogenesis protein CycZ; two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 996722 dipZ 3430347 dipZ Haemophilus influenzae 86-028NP thiol:disulfide interchange protein YP_248584.1 994983 D 281310 CDS YP_248585.1 68249473 3430348 996839..997243 1 NC_007146.2 Similar to: HI0886, Y886_HAEIN; hypothetical protein 997243 3430348 NTHI1049 Haemophilus influenzae 86-028NP hypothetical protein YP_248585.1 996839 D 281310 CDS YP_248586.1 68249474 3430349 997432..999030 1 NC_007146.2 AICAR transformylase; inosinicase; IMP synthetase; ATIC; involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 999030 purH 3430349 purH Haemophilus influenzae 86-028NP bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_248586.1 997432 D 281310 CDS YP_248587.1 68249475 3430350 999126..1000415 1 NC_007146.2 GARS; glycinamide ribonucleotide synthetase; phosphoribosylglycinamide synthetase; catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 1000415 purD 3430350 purD Haemophilus influenzae 86-028NP phosphoribosylamine--glycine ligase YP_248587.1 999126 D 281310 CDS YP_248588.1 68249476 3430352 1002261..1003526 1 NC_007146.2 Serine methylase; SHMT; catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1003526 glyA 3430352 glyA Haemophilus influenzae 86-028NP serine hydroxymethyltransferase YP_248588.1 1002261 D 281310 CDS YP_248589.1 68249477 3430353 1003585..1004217 1 NC_007146.2 dephosphocoenzyme A kinase; catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1004217 coaE 3430353 coaE Haemophilus influenzae 86-028NP dephospho-CoA kinase YP_248589.1 1003585 D 281310 CDS YP_248590.1 68249478 3430354 1004210..1004416 1 NC_007146.2 Similar to: HI0891, Y891_HAEIN; zinc-binding protein 1004416 3430354 NTHI1056 Haemophilus influenzae 86-028NP zinc-binding protein YP_248590.1 1004210 D 281310 CDS YP_248591.1 68249479 3430355 1004525..1005781 1 NC_007146.2 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 1005781 rhlB 3430355 rhlB Haemophilus influenzae 86-028NP ATP-dependent RNA helicase RhlB YP_248591.1 1004525 D 281310 CDS YP_248592.1 68249480 3430356 1006023..1006586 1 NC_007146.2 Similar to: HI0893, Y893_HAEIN; transcriptional regulator 1006586 3430356 NTHI1058 Haemophilus influenzae 86-028NP transcriptional regulator YP_248592.1 1006023 D 281310 CDS YP_248593.1 68249481 3430357 1006618..1007814 1 NC_007146.2 Similar to: HI0894, Y894_HAEIN; membrane-fusion protein 1007814 3430357 NTHI1059 Haemophilus influenzae 86-028NP membrane-fusion protein YP_248593.1 1006618 D 281310 CDS YP_248594.1 68249482 3430358 1007814..1010912 1 NC_007146.2 Similar to: HI0895, Y895_HAEIN; cation/multidrug efflux pump 1010912 3430358 NTHI1060 Haemophilus influenzae 86-028NP cation/multidrug efflux pump YP_248594.1 1007814 D 281310 CDS YP_248595.1 68249483 3430359 1011447..1011917 1 NC_007146.2 Similar to: HI0896, Y896_HAEIN; cell division protein 1011917 3430359 NTHI1061 Haemophilus influenzae 86-028NP cell division protein YP_248595.1 1011447 D 281310 CDS YP_248596.1 68249484 3430360 complement(1011930..1013462) 1 NC_007146.2 Similar to: HI0897, EMRB_HAEIN; multidrug resistance protein 1013462 emrB 3430360 emrB Haemophilus influenzae 86-028NP multidrug resistance protein YP_248596.1 1011930 R 281310 CDS YP_248597.1 68249485 3430361 complement(1013472..1014644) 1 NC_007146.2 Similar to: HI0898, EMRA_HAEIN; multidrug resistance protein A 1014644 emrA 3430361 emrA Haemophilus influenzae 86-028NP multidrug resistance protein A YP_248597.1 1013472 R 281310 CDS YP_248598.1 68249486 3430362 complement(1014817..1015299) 1 NC_007146.2 Similar to: HI0899, DYR_HAEIN; dihydrofolate reductase 1015299 folA 3430362 folA Haemophilus influenzae 86-028NP dihydrofolate reductase YP_248598.1 1014817 R 281310 CDS YP_248599.1 68249487 3430363 1015401..1016507 1 NC_007146.2 Gamma-glutamyl kinase; GK; catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1016507 proB 3430363 proB Haemophilus influenzae 86-028NP gamma-glutamyl kinase YP_248599.1 1015401 D 281310 CDS YP_248600.1 68249488 3430364 1016588..1017178 1 NC_007146.2 di; hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1017178 nudH 3430364 nudH Haemophilus influenzae 86-028NP dinucleoside polyphosphate hydrolase YP_248600.1 1016588 D 281310 CDS YP_248601.1 68249489 3430365 1017178..1017972 1 NC_007146.2 Similar to: HI0902, Y902_HAEIN; permease 1017972 3430365 NTHI1069 Haemophilus influenzae 86-028NP permease YP_248601.1 1017178 D 281310 CDS YP_248602.1 68249490 3430366 1017981..1018787 1 NC_007146.2 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1018787 lgt 3430366 lgt Haemophilus influenzae 86-028NP prolipoprotein diacylglyceryl transferase YP_248602.1 1017981 D 281310 CDS YP_248603.1 68249491 3430367 1018797..1019648 1 NC_007146.2 TS; TSase; ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1019648 thyA 3430367 thyA Haemophilus influenzae 86-028NP thymidylate synthase YP_248603.1 1018797 D 281310 CDS YP_248604.1 68249492 3430368 1019648..1020169 1 NC_007146.2 Similar to: HI0906, YFHC_HAEIN; hypothetical protein 1020169 3430368 NTHI1073 Haemophilus influenzae 86-028NP hypothetical protein YP_248604.1 1019648 D 281310 CDS YP_248605.1 68249493 3430369 complement(1020197..1020511) 1 NC_007146.2 Similar to: HI0907, Y907_HAEIN; hypothetical protein 1020511 3430369 NTHI1074 Haemophilus influenzae 86-028NP hypothetical protein YP_248605.1 1020197 R 281310 CDS YP_248606.1 68249494 3430370 1020582..1020893 1 NC_007146.2 Similar to: HI0908, Y908_HAEIN; hypothetical protein 1020893 3430370 NTHI1075 Haemophilus influenzae 86-028NP hypothetical protein YP_248606.1 1020582 D 281310 CDS YP_248607.1 68249495 3430371 1021018..1023723 1 NC_007146.2 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1023723 secA 3430371 secA Haemophilus influenzae 86-028NP preprotein translocase subunit SecA YP_248607.1 1021018 D 281310 CDS YP_248608.1 68249496 3430372 1023788..1024198 1 NC_007146.2 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase; Similar to: HI0910, MUTT_HAEIN; mutator protein MutT 1024198 mutT 3430372 mutT Haemophilus influenzae 86-028NP mutator protein MutT YP_248608.1 1023788 D 281310 CDS YP_248609.1 68249497 3430373 1024307..1026163 1 NC_007146.2 K(+)/H(+) antiporter; Similar to: HI0911, KEFX_HAEIN; glutathione-regulated potassium-efflux system protein 1026163 kefB 3430373 kefB Haemophilus influenzae 86-028NP glutathione-regulated potassium-efflux system protein YP_248609.1 1024307 D 281310 CDS YP_248610.1 68249498 3430374 1026264..1027028 1 NC_007146.2 Similar to: HI0912, Y912_HAEIN; hypothetical protein 1027028 3430374 NTHI1079 Haemophilus influenzae 86-028NP hypothetical protein YP_248610.1 1026264 D 281310 CDS YP_248611.2 161761272 3430375 1027206..1027928 1 NC_007146.2 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1027928 rpsB 3430375 rpsB Haemophilus influenzae 86-028NP 30S ribosomal protein S2 YP_248611.2 1027206 D 281310 CDS YP_248612.1 68249500 3430376 1028062..1028913 1 NC_007146.2 EF-Ts; EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1028913 tsf 3430376 tsf Haemophilus influenzae 86-028NP elongation factor Ts YP_248612.1 1028062 D 281310 CDS YP_248613.1 68249501 3430377 complement(1029093..1030118) 1 NC_007146.2 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 1030118 lpxD 3430377 lpxD Haemophilus influenzae 86-028NP UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_248613.1 1029093 R 281310 CDS YP_248614.1 68249502 3430378 complement(1030131..1030724) 1 NC_007146.2 Similar to: HI0916, OM26_HAEIN; hypothetical protein 1030724 omp26 3430378 omp26 Haemophilus influenzae 86-028NP hypothetical protein YP_248614.1 1030131 R 281310 CDS YP_248615.1 68249503 3430379 complement(1030832..1033234) 1 NC_007146.2 Outer membrane protein D15; Similar to: HI0917, D152_HAEIN; protective surface antigen D15 1033234 3430379 NTHI1084 Haemophilus influenzae 86-028NP protective surface antigen D15 YP_248615.1 1030832 R 281310 CDS YP_248616.1 68249504 3430380 complement(1033254..1034585) 1 NC_007146.2 Similar to: HI0918, YAEL_HAEIN; zinc metalloprotease 1034585 3430380 NTHI1085 Haemophilus influenzae 86-028NP zinc metalloprotease YP_248616.1 1033254 R 281310 CDS YP_248617.1 68249505 3430381 complement(1034595..1035461) 1 NC_007146.2 CDP-diglyceride synthetase; CDP-diglyceride pyrophosphorylase; CDP-diacylglycerol synthase; CDS; CTP:phosphatidate cytidylyltransferase; CDP-DAG synthase; CDP-DG synthetase; Similar to: HI0919, CDSA_HAEIN; phosphatidate cytidylyltransferase 1035461 cdsA 3430381 cdsA Haemophilus influenzae 86-028NP phosphatidate cytidylyltransferase YP_248617.1 1034595 R 281310 CDS YP_248618.1 68249506 3430382 complement(1035479..1036198) 1 NC_007146.2 UPP synthetase; Di-trans-poly-cis-decaprenylcistransferase; undecaprenyl diphosphate synthase; UDS; Similar to: HI0920, UPPS_HAEIN; undecaprenyl pyrophosphate synthetase 1036198 uppS 3430382 uppS Haemophilus influenzae 86-028NP undecaprenyl pyrophosphate synthetase YP_248618.1 1035479 R 281310 CDS YP_248619.1 68249507 3430383 1036447..1039032 1 NC_007146.2 leucine--tRNA ligase; LeuRS; leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1039032 leuS 3430383 leuS Haemophilus influenzae 86-028NP leucyl-tRNA synthetase YP_248619.1 1036447 D 281310 CDS YP_248620.1 68249508 3430384 1039082..1039630 1 NC_007146.2 Similar to: HI0922, Y922_HAEIN; lipoprotein 1039630 3430384 NTHI1091 Haemophilus influenzae 86-028NP lipoprotein YP_248620.1 1039082 D 281310 CDS YP_248621.1 68249509 3430385 1039630..1040664 1 NC_007146.2 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1040664 holA 3430385 holA Haemophilus influenzae 86-028NP DNA polymerase III subunit delta YP_248621.1 1039630 D 281310 CDS YP_248622.1 68249510 3430387 complement(1040898..1043066) 1 NC_007146.2 glycine--tRNA ligase beta chain; GlyRS; glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 1043066 glyS 3430387 glyS Haemophilus influenzae 86-028NP glycyl-tRNA synthetase subunit beta YP_248622.1 1040898 R 281310 CDS YP_248623.1 68249511 3430388 complement(1043112..1043528) 1 NC_007146.2 hypothetical protein 1043528 3430388 NTHI1094 Haemophilus influenzae 86-028NP hypothetical protein YP_248623.1 1043112 R 281310 CDS YP_248624.1 68249512 3430389 complement(1043668..1044033) 1 NC_007146.2 Similar to: HI0925, Y925_HAEIN; hypothetical protein 1044033 3430389 NTHI1095 Haemophilus influenzae 86-028NP hypothetical protein YP_248624.1 1043668 R 281310 CDS YP_248625.1 68249513 3430390 complement(1044063..1044323) 1 NC_007146.2 Similar to: HI0926, Y926_HAEIN; glutaredoxin-like protein 1044323 3430390 NTHI1097 Haemophilus influenzae 86-028NP glutaredoxin-like protein YP_248625.1 1044063 R 281310 CDS YP_248626.1 68249514 3430391 complement(1044382..1045290) 1 NC_007146.2 glycine--tRNA ligase alpha chain; GlyRS; glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1045290 glyQ 3430391 glyQ Haemophilus influenzae 86-028NP glycyl-tRNA synthetase subunit alpha YP_248626.1 1044382 R 281310 CDS YP_248627.1 68249515 3430392 1045553..1047079 1 NC_007146.2 Similar to: HI0928, CATA_HAEIN; catalase 1047079 hktE 3430392 hktE Haemophilus influenzae 86-028NP catalase YP_248627.1 1045553 D 281310 CDS YP_248628.1 68249516 3430393 complement(1047311..1048492) 1 NC_007146.2 Similar to: HI0929, YGIC_HAEIN; hypothetical protein 1048492 3430393 NTHI1100 Haemophilus influenzae 86-028NP hypothetical protein YP_248628.1 1047311 R 281310 CDS YP_248629.1 68249517 3430394 complement(1048493..1049074) 1 NC_007146.2 Similar to: HI0930, Y930_HAEIN; hypothetical protein 1049074 3430394 NTHI1101 Haemophilus influenzae 86-028NP hypothetical protein YP_248629.1 1048493 R 281310 CDS YP_248630.1 68249518 3430395 complement(1049087..1049539) 1 NC_007146.2 Similar to: HI0931, Y931_HAEIN; hypothetical protein 1049539 3430395 NTHI1102 Haemophilus influenzae 86-028NP hypothetical protein YP_248630.1 1049087 R 281310 CDS YP_248631.1 68249519 3430396 complement(1049590..1050900) 1 NC_007146.2 2-phosphoglycerate dehydratase; 2-phospho-D-glycerate hydro-lyase; enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1050900 eno 3430396 eno Haemophilus influenzae 86-028NP phosphopyruvate hydratase YP_248631.1 1049590 R 281310 CDS YP_248632.1 68249520 3430397 complement(1051021..1052226) 1 NC_007146.2 Similar to: HI0933, YHIN_HAEIN; hypothetical protein 1052226 3430397 NTHI1104 Haemophilus influenzae 86-028NP hypothetical protein YP_248632.1 1051021 R 281310 CDS YP_248633.1 68249521 3430398 complement(1052223..1053365) 1 NC_007146.2 Similar to: HI0934, NRFF_HAEIN; formate-dependent nitrite reductase complex nrfFG subunit 1053365 nrfF 3430398 nrfF Haemophilus influenzae 86-028NP formate-dependent nitrite reductase complex nrfFG subunit YP_248633.1 1052223 R 281310 CDS YP_248634.1 68249522 3430399 complement(1053362..1053892) 1 NC_007146.2 cytochrome c biogenesis protein nrfX; Similar to: HI0935, NRFX_HAEIN; thiol:disulfide interchange protein DsbE 1053892 dsbE2 3430399 dsbE2 Haemophilus influenzae 86-028NP thiol:disulfide interchange protein DsbE YP_248634.1 1053362 R 281310 CDS YP_248635.1 68249523 3430400 complement(1053892..1055799) 1 NC_007146.2 Similar to: HI0936, NRFE_HAEIN; cytochrome c-type biogenesis protein NrfE 1055799 nrfE 3430400 nrfE Haemophilus influenzae 86-028NP cytochrome c-type biogenesis protein NrfE YP_248635.1 1053892 R 281310 CDS YP_248636.1 68249524 3430401 complement(1055908..1056720) 1 NC_007146.2 IMPase; inositol-1-phosphatase; I-1-Pase; Similar to: HI0937, SUHB_HAEIN; inositol monophosphatase 1056720 suhB 3430401 suhB Haemophilus influenzae 86-028NP inositol monophosphatase YP_248636.1 1055908 R 281310 CDS YP_248637.1 68249525 3430402 1056920..1057432 1 NC_007146.2 Similar to: HI0938, Y938_HAEIN; hypothetical protein 1057432 3430402 NTHI1109 Haemophilus influenzae 86-028NP hypothetical protein YP_248637.1 1056920 D 281310 CDS YP_248638.1 68249526 3430403 1057432..1058151 1 NC_007146.2 Similar to: HI0939, Y939_HAEIN; hypothetical protein 1058151 3430403 NTHI1110 Haemophilus influenzae 86-028NP hypothetical protein YP_248638.1 1057432 D 281310 CDS YP_248639.1 68249527 3430404 1058148..1058831 1 NC_007146.2 Similar to: HI0940, Y940_HAEIN; hypothetical protein 1058831 3430404 NTHI1111 Haemophilus influenzae 86-028NP hypothetical protein YP_248639.1 1058148 D 281310 CDS YP_248640.1 68249528 3430405 1058836..1059111 1 NC_007146.2 Similar to: HI0941, Y941_HAEIN; hypothetical protein 1059111 3430405 NTHI1112 Haemophilus influenzae 86-028NP hypothetical protein YP_248640.1 1058836 D 281310 CDS YP_248641.1 68249529 3430406 1059157..1062522 1 NC_007146.2 Similar to: HI0942, EX5C_HAEIN; exodeoxyribonuclease V subunit gamma 1062522 recC 3430406 recC Haemophilus influenzae 86-028NP exodeoxyribonuclease V subunit gamma YP_248641.1 1059157 D 281310 CDS YP_248642.1 68249530 3430407 1062577..1063026 1 NC_007146.2 Similar to: HI0943, YBAD_HAEIN; Zn-ribbon and ATP-cone domains; transcriptional regulator NrdR 1063026 nrdR 3430407 nrdR Haemophilus influenzae 86-028NP transcriptional regulator NrdR YP_248642.1 1062577 D 281310 CDS YP_248643.1 68249531 3430408 1063029..1064147 1 NC_007146.2 riboflavin-specific deaminase; HTP reductase; Similar to: HI0944, RIBD_HAEIN; riboflavin biosynthesis protein RibD 1064147 ribD 3430408 ribD Haemophilus influenzae 86-028NP riboflavin biosynthesis protein RibD YP_248643.1 1063029 D 281310 CDS YP_248644.1 68249532 3430409 1064148..1065170 1 NC_007146.2 Similar to: HI0945, DEGS_HAEIN; protease DegS 1065170 degS 3430409 degS Haemophilus influenzae 86-028NP protease DegS YP_248644.1 1064148 D 281310 CDS YP_248645.1 68249533 3430410 complement(1065244..1066059) 1 NC_007146.2 FAPY-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 1066059 mutM 3430410 mutM Haemophilus influenzae 86-028NP formamidopyrimidine-DNA glycosylase YP_248645.1 1065244 R 281310 CDS YP_248646.1 68249534 3430411 complement(1066291..1067826) 1 NC_007146.2 DABA decarboxylase; DABA-DC; Similar to: HI0946.1, DDC_HAEIN; L-2,4-diaminobutyrate decarboxylase 1067826 ddc 3430411 ddc Haemophilus influenzae 86-028NP L-2,4-diaminobutyrate decarboxylase YP_248646.1 1066291 R 281310 CDS YP_248647.1 68249535 3430412 complement(1067846..1068244) 1 NC_007146.2 Similar to: HI0947, Y947_HAEIN; nucleic acid-binding protein 1068244 3430412 NTHI1120 Haemophilus influenzae 86-028NP nucleic acid-binding protein YP_248647.1 1067846 R 281310 CDS YP_248648.1 68249536 3430413 complement(1068244..1068477) 1 NC_007146.2 Similar to: HI0948, Y948_HAEIN; hypothetical protein 1068477 3430413 NTHI1121 Haemophilus influenzae 86-028NP hypothetical protein YP_248648.1 1068244 R 281310 CDS YP_248649.1 68249537 3430414 complement(1068624..1069988) 1 NC_007146.2 L-diaminobutyric acid transaminase; diaminobutyrate transaminase; DABA aminotransferase; DABA-AT; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase 1069988 dat 3430414 dat Haemophilus influenzae 86-028NP diaminobutyrate--2-oxoglutarate aminotransferase YP_248649.1 1068624 R 281310 CDS YP_248650.1 68249538 3430415 complement(1070335..1070505) 1 NC_007146.2 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1070505 rpmG 3430415 rpmG Haemophilus influenzae 86-028NP 50S ribosomal protein L33 YP_248650.1 1070335 R 281310 CDS YP_248651.1 68249539 3430416 complement(1070517..1070753) 1 NC_007146.2 required for 70S ribosome assembly; 50S ribosomal protein L28 1070753 rpmB 3430416 rpmB Haemophilus influenzae 86-028NP 50S ribosomal protein L28 YP_248651.1 1070517 R 281310 CDS YP_248652.1 68249540 3430417 complement(1070967..1071671) 1 NC_007146.2 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1071671 radC 3430417 radC Haemophilus influenzae 86-028NP DNA repair protein RadC YP_248652.1 1070967 R 281310 CDS YP_248653.1 68249541 3430418 1071795..1072997 1 NC_007146.2 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 1072997 dfp 3430418 dfp Haemophilus influenzae 86-028NP bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_248653.1 1071795 D 281310 CDS YP_248654.1 68249542 3430419 1073045..1073500 1 NC_007146.2 dUTPase; dUTP pyrophosphatase; catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 1073500 dut 3430419 dut Haemophilus influenzae 86-028NP deoxyuridine 5'-triphosphate nucleotidohydrolase YP_248654.1 1073045 D 281310 CDS YP_248655.1 68249543 3430420 1073504..1074160 1 NC_007146.2 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 1074160 slmA 3430420 slmA Haemophilus influenzae 86-028NP nucleoid occlusion protein YP_248655.1 1073504 D 281310 CDS YP_248656.1 68249544 3430421 1074182..1074433 1 NC_007146.2 Similar to: Y956_HAEIN; hypothetical protein 1074433 3430421 NTHI1129 Haemophilus influenzae 86-028NP hypothetical protein YP_248656.1 1074182 D 281310 CDS YP_248657.1 68249545 3430422 1074418..1075092 1 NC_007146.2 cAMP receptor protein; cAMP-regulatory protein; complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 1075092 crp 3430422 crp Haemophilus influenzae 86-028NP cAMP-regulatory protein YP_248657.1 1074418 D 281310 CDS YP_248658.1 68249546 3430423 complement(1075457..1076635) 1 NC_007146.2 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 1076635 rumB 3430423 rumB Haemophilus influenzae 86-028NP 23S rRNA methyluridine methyltransferase YP_248658.1 1075457 R 281310 CDS YP_248659.1 68249547 3430424 complement(1076628..1077683) 1 NC_007146.2 N-acetyl-beta-glucosaminidase; Beta-N-acetylhexosaminidase; hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1077683 nagZ 3430424 nagZ Haemophilus influenzae 86-028NP beta-hexosaminidase YP_248659.1 1076628 R 281310 CDS YP_248660.1 68249548 3430425 complement(1077687..1078037) 1 NC_007146.2 Similar to: HI0960, Y960_HAEIN; periplasmic lipoprotein 1078037 3430425 NTHI1133 Haemophilus influenzae 86-028NP periplasmic lipoprotein YP_248660.1 1077687 R 281310 CDS YP_248661.1 68249549 3430426 complement(1078037..1078429) 1 NC_007146.2 Similar to: HI0961, YCFF_HAEIN; HIT-like protein 1078429 3430426 NTHI1134 Haemophilus influenzae 86-028NP HIT-like protein YP_248661.1 1078037 R 281310 CDS YP_248662.1 68249550 3430427 complement(1078504..1081329) 1 NC_007146.2 isoleucine--tRNA ligase; IleRS; IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1081329 ileS 3430427 ileS Haemophilus influenzae 86-028NP isoleucyl-tRNA synthetase YP_248662.1 1078504 R 281310 CDS YP_248663.1 68249551 3430428 complement(1081358..1082296) 1 NC_007146.2 flavokinase; FAD pyrophosphorylase; FAD synthetase; catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1082296 ribF 3430428 ribF Haemophilus influenzae 86-028NP bifunctional riboflavin kinase/FMN adenylyltransferase YP_248663.1 1081358 R 281310 CDS YP_248664.1 68249552 3430429 complement(1082331..1083863) 1 NC_007146.2 Similar to: HI0964, MVIN_HAEIN; virulence factor MviN 1083863 mviN 3430429 mviN Haemophilus influenzae 86-028NP virulence factor MviN YP_248664.1 1082331 R 281310 CDS YP_248665.2 161761271 3430430 1084172..1084435 1 NC_007146.2 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1084435 rpsT 3430430 rpsT Haemophilus influenzae 86-028NP 30S ribosomal protein S20 YP_248665.2 1084172 D 281310 CDS YP_248666.1 68249554 3430431 complement(1084507..1085073) 1 NC_007146.2 Similar to: HI0966, Y966_HAEIN; hypothetical protein 1085073 3430431 NTHI1140 Haemophilus influenzae 86-028NP hypothetical protein YP_248666.1 1084507 R 281310 CDS YP_248667.1 68249555 3430432 1085219..1086076 1 NC_007146.2 dihydroxynaphthoic acid synthetase; DHNA synthetase; catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 1086076 menB 3430432 menB Haemophilus influenzae 86-028NP naphthoate synthase YP_248667.1 1085219 D 281310 CDS YP_248668.1 68249556 3430433 1086246..1087235 1 NC_007146.2 OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; O-succinylbenzoic acid synthase; catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 1087235 menC 3430433 menC Haemophilus influenzae 86-028NP O-succinylbenzoate synthase YP_248668.1 1086246 D 281310 CDS YP_248669.1 68249557 3430434 1087292..1087741 1 NC_007146.2 3-dehydroquinase; Type II DHQase; catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 1087741 aroQ 3430434 aroQ Haemophilus influenzae 86-028NP 3-dehydroquinate dehydratase YP_248669.1 1087292 D 281310 CDS YP_248670.1 68249558 3430435 1087895..1088362 1 NC_007146.2 BCCP; composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 1088362 accB 3430435 accB Haemophilus influenzae 86-028NP acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_248670.1 1087895 D 281310 CDS YP_248671.1 68249559 3430436 1088539..1089885 1 NC_007146.2 A subunit of acetyl-CoA carboxylase; an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 1089885 accC 3430436 accC Haemophilus influenzae 86-028NP acetyl-CoA carboxylase biotin carboxylase subunit YP_248671.1 1088539 D 281310 CDS YP_248672.1 68249560 3430437 1090090..1090347 1 NC_007146.2 Similar to: HI0974.1, YHDT_HAEIN; hypothetical protein 1090347 3430437 NTHI1146 Haemophilus influenzae 86-028NP hypothetical protein YP_248672.1 1090090 D 281310 CDS YP_248673.1 68249561 3430438 1090344..1091798 1 NC_007146.2 pantothenate permease; mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 1091798 panF 3430438 panF Haemophilus influenzae 86-028NP sodium/panthothenate symporter YP_248673.1 1090344 D 281310 CDS YP_248674.1 68249562 3430439 1091919..1092791 1 NC_007146.2 Similar to: HI0976.1, Y97X_HAEIN; hypothetical protein 1092791 3430439 NTHI1148 Haemophilus influenzae 86-028NP hypothetical protein YP_248674.1 1091919 D 281310 CDS YP_248675.1 68249563 3430440 1092826..1093713 1 NC_007146.2 L11 Mtase; methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 1093713 prmA 3430440 prmA Haemophilus influenzae 86-028NP ribosomal protein L11 methyltransferase YP_248675.1 1092826 D 281310 CDS YP_248676.1 68249564 3430441 1093860..1094840 1 NC_007146.2 Similar to: HI0979, DUSB_HAEIN; tRNA-dihydrouridine synthase B 1094840 dusB 3430441 dusB Haemophilus influenzae 86-028NP tRNA-dihydrouridine synthase B YP_248676.1 1093860 D 281310 CDS YP_248677.1 68249565 3430442 1094834..1095133 1 NC_007146.2 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; Fis family transcriptional regulator 1095133 fis 3430442 fis Haemophilus influenzae 86-028NP Fis family transcriptional regulator YP_248677.1 1094834 D 281310 CDS YP_248678.1 68249566 3430443 complement(1095234..1095719) 1 NC_007146.2 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1095719 smpB 3430443 smpB Haemophilus influenzae 86-028NP SsrA-binding protein YP_248678.1 1095234 R 281310 CDS YP_248679.1 68249567 3430444 complement(1095958..1096923) 1 NC_007146.2 phosphofructokinase; phosphohexokinase; catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1096923 pfkA 3430444 pfkA Haemophilus influenzae 86-028NP 6-phosphofructokinase YP_248679.1 1095958 R 281310 CDS YP_248680.1 68249568 3430445 complement(1097019..1097600) 1 NC_007146.2 Similar to: HI0983, Y983_HAEIN; hypothetical protein 1097600 3430445 NTHI1155 Haemophilus influenzae 86-028NP hypothetical protein YP_248680.1 1097019 R 281310 CDS YP_248681.1 68249569 3430446 complement(1097593..1098444) 1 NC_007146.2 Similar to: HI0984, Y984_HAEIN; hypothetical protein 1098444 3430446 NTHI1156 Haemophilus influenzae 86-028NP hypothetical protein YP_248681.1 1097593 R 281310 CDS YP_248682.1 68249570 3430447 complement(1098422..1099543) 1 NC_007146.2 DNA processing chain A; Similar to: HI0985, SMF_HAEIN; hypothetical protein 1099543 smf 3430447 smf Haemophilus influenzae 86-028NP hypothetical protein YP_248682.1 1098422 R 281310 CDS YP_248683.1 68249571 3430448 1100087..1101634 1 NC_007146.2 Alpha-isopropylmalate synthase; Alpha-IPM synthetase; catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 1101634 leuA 3430448 leuA Haemophilus influenzae 86-028NP 2-isopropylmalate synthase YP_248683.1 1100087 D 281310 CDS YP_248684.1 68249572 3430449 1101797..1102873 1 NC_007146.2 beta-IPM dehydrogenase; IMDH; 3-IPM-DH; catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1102873 leuB 3430449 leuB Haemophilus influenzae 86-028NP 3-isopropylmalate dehydrogenase YP_248684.1 1101797 D 281310 CDS YP_248685.1 68249573 3430450 1103050..1104459 1 NC_007146.2 isopropylmalate isomerase; alpha-IPM isomerase; IPMI; dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1104459 leuC 3430450 leuC Haemophilus influenzae 86-028NP isopropylmalate isomerase large subunit YP_248685.1 1103050 D 281310 CDS YP_248686.1 68249574 3430451 1104484..1105086 1 NC_007146.2 isopropylmalate isomerase; alpha-IPM isomerase; IPMI; catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 1105086 leuD 3430451 leuD Haemophilus influenzae 86-028NP isopropylmalate isomerase small subunit YP_248686.1 1104484 D 281310 CDS YP_248687.1 68249575 3430452 complement(1105200..1110584) 1 NC_007146.2 IgA protease; Similar to: HI0990, IGA_NEIGO; IgA-specific serine endopeptidase 1110584 iga1 3430452 iga1 Haemophilus influenzae 86-028NP IgA-specific serine endopeptidase YP_248687.1 1105200 R 281310 CDS YP_248688.1 68249576 3430453 complement(1110811..1111890) 1 NC_007146.2 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 1111890 recF 3430453 recF Haemophilus influenzae 86-028NP recombination protein F YP_248688.1 1110811 R 281310 CDS YP_248689.1 68249577 3430454 complement(1111892..1112992) 1 NC_007146.2 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1112992 dnaN 3430454 dnaN Haemophilus influenzae 86-028NP DNA polymerase III subunit beta YP_248689.1 1111892 R 281310 CDS YP_248690.1 68249578 3430455 complement(1113185..1114549) 1 NC_007146.2 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 1114549 dnaA 3430455 dnaA Haemophilus influenzae 86-028NP chromosome replication initiator DnaA YP_248690.1 1113185 R 281310 CDS YP_248691.1 68249579 3430456 complement(1114736..1117474) 1 NC_007146.2 Similar to: HI0994, TBP1_HAEIN; transferrin-binding protein 1 1117474 tbp1 3430456 tbp1 Haemophilus influenzae 86-028NP transferrin-binding protein 1 YP_248691.1 1114736 R 281310 CDS YP_248692.1 68249580 3430457 complement(1117519..1119411) 1 NC_007146.2 Similar to: HI0995, TBP2_HAEIN; transferrin-binding protein 2 1119411 tbp2 3430457 tbp2 Haemophilus influenzae 86-028NP transferrin-binding protein 2 YP_248692.1 1117519 R 281310 CDS YP_248693.1 68249581 3430458 1119508..1120968 1 NC_007146.2 Similar to: HI0997, Y997_HAEIN; hypothetical protein 1120968 3430458 NTHI1171 Haemophilus influenzae 86-028NP hypothetical protein YP_248693.1 1119508 D 281310 CDS YP_248694.1 68249582 3430459 1121144..1121278 1 NC_007146.2 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1121278 rpmH 3430459 rpmH Haemophilus influenzae 86-028NP 50S ribosomal protein L34 YP_248694.1 1121144 D 281310 CDS YP_248695.1 68249583 3430460 1121291..1121650 1 NC_007146.2 RNaseP protein; RNase P protein; protein C5; protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1121650 rnpA 3430460 rnpA Haemophilus influenzae 86-028NP ribonuclease P YP_248695.1 1121291 D 281310 CDS YP_248696.1 68249584 3430461 1121614..1121874 1 NC_007146.2 Similar to: HI1000, YA00_HAEIN; hypothetical protein 1121874 3430461 NTHI1174 Haemophilus influenzae 86-028NP hypothetical protein YP_248696.1 1121614 D 281310 CDS YP_248697.1 68249585 3430462 1121874..1123499 1 NC_007146.2 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 1123499 yidC 3430462 yidC Haemophilus influenzae 86-028NP inner membrane protein translocase component YidC YP_248697.1 1121874 D 281310 CDS YP_248698.1 68249586 3430463 1124370..1125728 1 NC_007146.2 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1125728 trmE 3430463 trmE Haemophilus influenzae 86-028NP tRNA modification GTPase TrmE YP_248698.1 1124370 D 281310 CDS YP_248699.1 68249587 3430464 1125917..1127785 1 NC_007146.2 PPIase D; rotamase D; Similar to: HI1004, PPID_HAEIN; peptidyl-prolyl cis-trans isomerase D 1127785 ppiD 3430464 ppiD Haemophilus influenzae 86-028NP peptidyl-prolyl cis-trans isomerase D YP_248699.1 1125917 D 281310 CDS YP_248700.1 68249588 3430465 1127873..1129432 1 NC_007146.2 Similar to: HI1005, YA05_HAEIN; PE--lipooligosaccharide phosphorylethanolamine transferase 1129432 3430465 NTHI1180 Haemophilus influenzae 86-028NP PE--lipooligosaccharide phosphorylethanolamine transferase YP_248700.1 1127873 D 281310 CDS YP_248701.1 68249589 3430466 1129502..1130017 1 NC_007146.2 prolipoprotein signal peptidase; signal peptidase II; SPase II; lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1130017 lspA 3430466 lspA Haemophilus influenzae 86-028NP lipoprotein signal peptidase YP_248701.1 1129502 D 281310 CDS YP_248702.1 68249590 3430467 1130014..1130958 1 NC_007146.2 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1130958 ispH 3430467 ispH Haemophilus influenzae 86-028NP 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_248702.1 1130014 D 281310 CDS YP_248703.1 68249591 3430468 1131127..1131474 1 NC_007146.2 Similar to: HI1008, YBAV_HAEIN; hypothetical protein 1131474 3430468 NTHI1183 Haemophilus influenzae 86-028NP hypothetical protein YP_248703.1 1131127 D 281310 CDS YP_248704.1 68249592 3430469 1131721..1132719 1 NC_007146.2 Similar to: HI1019, TBPA_HAEIN; thiamine-binding periplasmic protein 1132719 tbpA 3430469 tbpA Haemophilus influenzae 86-028NP thiamine-binding periplasmic protein YP_248704.1 1131721 D 281310 CDS YP_248705.1 68249593 3430470 1132724..1134340 1 NC_007146.2 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 1134340 thiP 3430470 thiP Haemophilus influenzae 86-028NP thiamine transporter membrane protein YP_248705.1 1132724 D 281310 CDS YP_248706.1 68249594 3430471 1134318..1134971 1 NC_007146.2 Similar to: HI1021, THIQ_HAEIN; thiamine transport ATP-binding protein 1134971 thiQ 3430471 thiQ Haemophilus influenzae 86-028NP thiamine transport ATP-binding protein YP_248706.1 1134318 D 281310 CDS YP_248707.1 68249595 3430472 1135084..1136085 1 NC_007146.2 biotin synthetase; Similar to: HI1022, BIOB_HAEIN; biotin synthase 1136085 bioB 3430472 bioB Haemophilus influenzae 86-028NP biotin synthase YP_248707.1 1135084 D 281310 CDS YP_248708.1 68249596 3430473 complement(1136210..1138207) 1 NC_007146.2 TK; catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1138207 tktA 3430473 tktA Haemophilus influenzae 86-028NP transketolase YP_248708.1 1136210 R 281310 CDS YP_248709.1 68249597 3430474 1138588..1139532 1 NC_007146.2 PSP; O-phosphoserine phosphohydrolase; PSPase; catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 1139532 serB 3430474 serB Haemophilus influenzae 86-028NP phosphoserine phosphatase YP_248709.1 1138588 D 281310 CDS YP_248710.1 68249598 3430475 1139550..1140041 1 NC_007146.2 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 1140041 3430475 NTHI1194 Haemophilus influenzae 86-028NP nucleotide-binding protein YP_248710.1 1139550 D 281310 CDS YP_248711.1 68249599 3430476 1140337..1141284 1 NC_007146.2 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 1141284 corA 3430476 corA Haemophilus influenzae 86-028NP magnesium/nickel/cobalt transporter CorA YP_248711.1 1140337 D 281310 CDS YP_248712.1 68249600 3430477 1141275..1141829 1 NC_007146.2 Similar to: HI1036, YGGT_HAEIN; hypothetical protein 1141829 3430477 NTHI1196 Haemophilus influenzae 86-028NP hypothetical protein YP_248712.1 1141275 D 281310 CDS YP_248713.1 68249601 3430478 complement(1142009..1142893) 1 NC_007146.2 Similar to: HI1037, YAFJ_HAEIN; hypothetical protein 1142893 3430478 NTHI1197 Haemophilus influenzae 86-028NP hypothetical protein YP_248713.1 1142009 R 281310 CDS YP_248714.1 68249602 3430479 complement(1143050..1143577) 1 NC_007146.2 hypothetical protein 1143577 3430479 NTHI1198 Haemophilus influenzae 86-028NP hypothetical protein YP_248714.1 1143050 R 281310 CDS YP_248715.1 68249603 3430480 1143707..1144909 1 NC_007146.2 Similar to: HI1038, YA38_HAEIN; ATPase 1144909 3430480 NTHI1199 Haemophilus influenzae 86-028NP ATPase YP_248715.1 1143707 D 281310 CDS YP_248716.1 68249604 3430481 complement(1145099..1146448) 1 NC_007146.2 hypothetical protein 1146448 3430481 NTHI1201 Haemophilus influenzae 86-028NP hypothetical protein YP_248716.1 1145099 R 281310 CDS YP_248717.1 68249605 3430482 complement(1146916..1147416) 1 NC_007146.2 Similar to: HI1043, YA43_HAEIN; ferredoxin 1147416 3430482 NTHI1203 Haemophilus influenzae 86-028NP ferredoxin YP_248717.1 1146916 R 281310 CDS YP_248718.1 68249606 3430483 complement(1147416..1148027) 1 NC_007146.2 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1148027 3430483 NTHI1204 Haemophilus influenzae 86-028NP twin-argninine leader-binding protein DmsD YP_248718.1 1147416 R 281310 CDS YP_248719.1 68249607 3430484 complement(1148139..1148978) 1 NC_007146.2 DMSO reductase anchor subunit; Similar to: HI1045, DMSC_HAEIN; anaerobic dimethyl sulfoxide reductase chain C 1148978 dmsC 3430484 dmsC Haemophilus influenzae 86-028NP anaerobic dimethyl sulfoxide reductase chain C YP_248719.1 1148139 R 281310 CDS YP_248720.1 68249608 3430485 complement(1148980..1149597) 1 NC_007146.2 DMSO reductase iron-sulfur subunit; Similar to: HI1046, DMSB_HAEIN; anaerobic dimethyl sulfoxide reductase chain B 1149597 dmsB 3430485 dmsB Haemophilus influenzae 86-028NP anaerobic dimethyl sulfoxide reductase chain B YP_248720.1 1148980 R 281310 CDS YP_248721.1 68249609 3430486 complement(1149608..1152028) 1 NC_007146.2 DMSO reductase; Similar to: HI1047, DMSA_HAEIN; anaerobic dimethyl sulfoxide reductase chain A 1152028 dmsA 3430486 dmsA Haemophilus influenzae 86-028NP anaerobic dimethyl sulfoxide reductase chain A YP_248721.1 1149608 R 281310 CDS YP_248722.1 68249610 3430487 1152281..1153390 1 NC_007146.2 Similar to: HI1048, YA48_HAEIN; hypothetical protein 1153390 3430487 NTHI1208 Haemophilus influenzae 86-028NP hypothetical protein YP_248722.1 1152281 D 281310 CDS YP_248723.1 68249611 3430488 1153434..1153727 1 NC_007146.2 Similar to: HI1049, YA49_HAEIN; mercuric transporter MerT 1153727 3430488 NTHI1209 Haemophilus influenzae 86-028NP mercuric transporter MerT YP_248723.1 1153434 D 281310 CDS YP_248724.1 68249612 3430489 1153736..1154014 1 NC_007146.2 Similar to: HI1050, YA50_HAEIN; copper chaperone MerP-like protein 1154014 3430489 NTHI1211 Haemophilus influenzae 86-028NP copper chaperone MerP-like protein YP_248724.1 1153736 D 281310 CDS YP_248725.1 68249613 3430490 complement(1154139..1155983) 1 NC_007146.2 Similar to: HI1051, YA51_HAEIN; ABC transporter ATP-binding protein 1155983 3430490 NTHI1212 Haemophilus influenzae 86-028NP ABC transporter ATP-binding protein YP_248725.1 1154139 R 281310 CDS YP_248726.1 68249614 3430491 complement(1156062..1156958) 1 NC_007146.2 Similar to: HI1052, YA52_HAEIN; transcriptional regulator 1156958 3430491 NTHI1213 Haemophilus influenzae 86-028NP transcriptional regulator YP_248726.1 1156062 R 281310 CDS YP_248727.1 68249615 3430492 1157070..1157411 1 NC_007146.2 Similar to: HI1053, YA53_HAEIN; hypothetical protein 1157411 3430492 NTHI1214 Haemophilus influenzae 86-028NP hypothetical protein YP_248727.1 1157070 D 281310 CDS YP_248728.1 68249616 3430493 complement(1157522..1158118) 1 NC_007146.2 Similar to: HI1054, YA54_HAEIN; hypothetical protein 1158118 3430493 NTHI1215 Haemophilus influenzae 86-028NP hypothetical protein YP_248728.1 1157522 R 281310 CDS YP_248729.1 68249617 3430494 complement(1158124..1160289) 1 NC_007146.2 Similar to: HI1055, T3RH_HAEIN; type III restriction-modification system HindVIP enzyme res 1160289 res 3430494 res Haemophilus influenzae 86-028NP type III restriction-modification system HindVIP enzyme res YP_248729.1 1158124 R 281310 CDS YP_248730.1 68249618 3430496 complement(1162596..1163189) 1 NC_007146.2 RNase HII; RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1163189 rnhB 3430496 rnhB Haemophilus influenzae 86-028NP ribonuclease HII YP_248730.1 1162596 R 281310 CDS YP_248731.1 68249619 3430497 complement(1163182..1164354) 1 NC_007146.2 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 1164354 lpxB 3430497 lpxB Haemophilus influenzae 86-028NP lipid-A-disaccharide synthase YP_248731.1 1163182 R 281310 CDS YP_248732.1 68249620 3430498 complement(1164421..1165209) 1 NC_007146.2 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 1165209 lpxA 3430498 lpxA Haemophilus influenzae 86-028NP UDP-N-acetylglucosamine acyltransferase YP_248732.1 1164421 R 281310 CDS YP_248733.1 68249621 3430499 complement(1165223..1165669) 1 NC_007146.2 (3R)-hydroxymyristoyl ACP dehydrase; in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1165669 fabZ 3430499 fabZ Haemophilus influenzae 86-028NP (3R)-hydroxymyristoyl-ACP dehydratase YP_248733.1 1165223 R 281310 CDS YP_248734.1 68249622 3430500 complement(1165745..1167352) 1 NC_007146.2 Similar to: HI1064, YA64_HAEIN; PE--lipooligosaccharide phosphorylethanolamine transferase 1167352 3430500 NTHI1224 Haemophilus influenzae 86-028NP PE--lipooligosaccharide phosphorylethanolamine transferase YP_248734.1 1165745 R 281310 CDS YP_248735.1 68249623 3430501 1167445..1168158 1 NC_007146.2 UK; uridine monophosphate kinase; UMP kinase; Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1168158 pyrH 3430501 pyrH Haemophilus influenzae 86-028NP uridylate kinase YP_248735.1 1167445 D 281310 CDS YP_248736.1 68249624 3430502 complement(1168397..1169362) 1 NC_007146.2 Similar to: HI1066, NRFD_HAEIN; NrfD, formate-dependent nitrite reductase, membrane component 1169362 nrfD 3430502 nrfD Haemophilus influenzae 86-028NP NrfD, formate-dependent nitrite reductase, membrane component YP_248736.1 1168397 R 281310 CDS YP_248737.1 68249625 3430503 complement(1169359..1170036) 1 NC_007146.2 Similar to: HI1067, NRFC_HAEIN; NrfC, Fe-S-cluster-containing hydrogenase component 1 1170036 nrfC 3430503 nrfC Haemophilus influenzae 86-028NP NrfC, Fe-S-cluster-containing hydrogenase component 1 YP_248737.1 1169359 R 281310 CDS YP_248738.1 68249626 3430504 complement(1170033..1170716) 1 NC_007146.2 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 1170716 nrfB 3430504 nrfB Haemophilus influenzae 86-028NP cytochrome c nitrite reductase pentaheme subunit YP_248738.1 1170033 R 281310 CDS YP_248739.1 68249627 3430505 complement(1170760..1172376) 1 NC_007146.2 ammonia-forming cytochrome c nitrite reductase; cytochrome c nitrite reductase; catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 1172376 nrfA 3430505 nrfA Haemophilus influenzae 86-028NP cytochrome c552 YP_248739.1 1170760 R 281310 CDS YP_248740.2 161761270 3430506 complement(1172538..1176374) 1 NC_007146.2 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1176374 hrpA 3430506 hrpA Haemophilus influenzae 86-028NP ATP-dependent RNA helicase HrpA YP_248740.2 1172538 R 281310 CDS YP_248741.1 68249629 3430507 complement(1176443..1176817) 1 NC_007146.2 Similar to: HI1073, YGDD_HAEIN; small membrane protein 1176817 3430507 NTHI1232 Haemophilus influenzae 86-028NP small membrane protein YP_248741.1 1176443 R 281310 CDS YP_248742.1 68249630 3430508 complement(1176818..1177270) 1 NC_007146.2 Similar to: HI1074, YEAL_HAEIN; hypothetical protein 1177270 3430508 NTHI1233 Haemophilus influenzae 86-028NP hypothetical protein YP_248742.1 1176818 R 281310 CDS YP_248743.1 68249631 3430509 complement(1177536..1178672) 1 NC_007146.2 Similar to: HI1075, CYOB_HAEIN; cytochrome oxidase subunit II 1178672 cyoB 3430509 cyoB Haemophilus influenzae 86-028NP cytochrome oxidase subunit II YP_248743.1 1177536 R 281310 CDS YP_248744.1 68249632 3430510 complement(1178687..1180252) 1 NC_007146.2 Similar to: HI1076, CYOA_HAEIN; cytochrome oxidase subunit I 1180252 cyoA 3430510 cyoA Haemophilus influenzae 86-028NP cytochrome oxidase subunit I YP_248744.1 1178687 R 281310 CDS YP_248745.1 68249633 3430511 1180905..1182542 1 NC_007146.2 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1182542 pyrG 3430511 pyrG Haemophilus influenzae 86-028NP CTP synthetase YP_248745.1 1180905 D 281310 CDS YP_248746.1 68249634 3430512 complement(1182687..1183367) 1 NC_007146.2 NR; Similar to: HI1077.1, YA7B_HAEIN; nicotinamide riboside transporter 1183367 pnuC 3430512 pnuC Haemophilus influenzae 86-028NP nicotinamide riboside transporter YP_248746.1 1182687 R 281310 CDS YP_248747.1 68249635 3430513 complement(1183549..1184322) 1 NC_007146.2 Similar to: HI1078, YA78_HAEIN; amino-acid ABC transporter ATP-binding protein 1184322 3430513 NTHI1241 Haemophilus influenzae 86-028NP amino-acid ABC transporter ATP-binding protein YP_248747.1 1183549 R 281310 CDS YP_248748.1 68249636 3430514 complement(1184326..1185003) 1 NC_007146.2 Similar to: HI1079, YA79_HAEIN; amino-acid ABC transporter permease protein 1185003 3430514 NTHI1242 Haemophilus influenzae 86-028NP amino-acid ABC transporter permease protein YP_248748.1 1184326 R 281310 CDS YP_248749.1 68249637 3430515 complement(1185026..1185799) 1 NC_007146.2 Similar to: HI1080, YA80_HAEIN; amino-acid ABC transporter binding protein 1185799 3430515 NTHI1243 Haemophilus influenzae 86-028NP amino-acid ABC transporter binding protein YP_248749.1 1185026 R 281310 CDS YP_248750.1 68249638 3430516 complement(1186100..1187374) 1 NC_007146.2 enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT; adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1187374 murA 3430516 murA Haemophilus influenzae 86-028NP UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_248750.1 1186100 R 281310 CDS YP_248751.1 68249639 3430517 complement(1187385..1187642) 1 NC_007146.2 Similar to: HI1082, YRBA_HAEIN; BolA family transcriptional regulator 1187642 3430517 NTHI1245 Haemophilus influenzae 86-028NP BolA family transcriptional regulator YP_248751.1 1187385 R 281310 CDS YP_248752.1 68249640 3430518 complement(1187663..1187980) 1 NC_007146.2 Similar to: HI1083, YA83_HAEIN; NTP binding protein, contains STAS domain 1187980 3430518 NTHI1246 Haemophilus influenzae 86-028NP NTP binding protein, contains STAS domain YP_248752.1 1187663 R 281310 CDS YP_248753.1 68249641 3430519 complement(1187991..1188635) 1 NC_007146.2 Similar to: HI1084, YRBC_HAEIN; ABC transporter 1188635 3430519 NTHI1247 Haemophilus influenzae 86-028NP ABC transporter YP_248753.1 1187991 R 281310 CDS YP_248754.1 68249642 3430520 complement(1188668..1189168) 1 NC_007146.2 Similar to: HI1085, YRBD_HAEIN; ABC transporter periplasmic protein 1189168 3430520 NTHI1248 Haemophilus influenzae 86-028NP ABC transporter periplasmic protein YP_248754.1 1188668 R 281310 CDS YP_248755.1 68249643 3430521 complement(1189178..1189963) 1 NC_007146.2 Similar to: HI1086, YRBE_HAEIN; ABC transporter permease 1189963 3430521 NTHI1249 Haemophilus influenzae 86-028NP ABC transporter permease YP_248755.1 1189178 R 281310 CDS YP_248756.1 68249644 3430522 complement(1189960..1190754) 1 NC_007146.2 Similar to: HI1087, YRBF_HAEIN; ABC transporter ATPase 1190754 3430522 NTHI1250 Haemophilus influenzae 86-028NP ABC transporter ATPase YP_248756.1 1189960 R 281310 CDS YP_248757.1 68249645 3430523 complement(1191160..1191807) 1 NC_007146.2 Mn; Similar to: HI1088, SODM_HAEIN; superoxide dismutase 1191807 sodA 3430523 sodA Haemophilus influenzae 86-028NP superoxide dismutase YP_248757.1 1191160 R 281310 CDS YP_248758.1 68249646 3430524 1192056..1192694 1 NC_007146.2 cytochrome c-type biogenesis ATP-binding protein CcmA; ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 1192694 ccmA 3430524 ccmA Haemophilus influenzae 86-028NP cytochrome c biogenesis protein CcmA YP_248758.1 1192056 D 281310 CDS YP_248759.1 68249647 3430525 1192699..1193364 1 NC_007146.2 cytochrome c-type biogenesis protein CcmB; Similar to: HI1090, CCMB_HAEIN; heme exporter protein B 1193364 ccmB 3430525 ccmB Haemophilus influenzae 86-028NP heme exporter protein B YP_248759.1 1192699 D 281310 CDS YP_248760.1 68249648 3430526 1193425..1194165 1 NC_007146.2 cytochrome c-type biogenesis protein CcmC; Similar to: HI1091, CCMC_HAEIN; heme exporter protein C 1194165 ccmC 3430526 ccmC Haemophilus influenzae 86-028NP heme exporter protein C YP_248760.1 1193425 D 281310 CDS YP_248761.1 68249649 3430527 1194208..1194411 1 NC_007146.2 cytochrome c-type biogenesis protein CcmD; Similar to: HI1092, CCMD_HAEIN; heme exporter protein D 1194411 ccmD 3430527 ccmD Haemophilus influenzae 86-028NP heme exporter protein D YP_248761.1 1194208 D 281310 CDS YP_248762.1 68249650 3430528 1194408..1194929 1 NC_007146.2 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 1194929 ccmE 3430528 ccmE Haemophilus influenzae 86-028NP cytochrome c-type biogenesis protein CcmE YP_248762.1 1194408 D 281310 CDS YP_248763.1 68249651 3430529 1194926..1196872 1 NC_007146.2 Similar to: HI1094, CCMF_HAEIN; cytochrome c-type biogenesis protein CcmF 1196872 ccmF 3430529 ccmF Haemophilus influenzae 86-028NP cytochrome c-type biogenesis protein CcmF YP_248763.1 1194926 D 281310 CDS YP_248764.1 68249652 3430530 1197015..1197560 1 NC_007146.2 cytochrome c biogenesis protein CcmG; Similar to: HI1095, DSBE_HAEIN; thiol-disulfide interchange protein 1197560 dsbE 3430530 dsbE Haemophilus influenzae 86-028NP thiol-disulfide interchange protein YP_248764.1 1197015 D 281310 CDS YP_248765.1 68249653 3430532 1199060..1199551 1 NC_007146.2 hypothetical protein 1199551 3430532 NTHI1262 Haemophilus influenzae 86-028NP hypothetical protein YP_248765.1 1199060 D 281310 CDS YP_248766.1 68249654 3430533 1199553..1199861 1 NC_007146.2 Similar to: HI1099, YA99_HAEIN; hypothetical protein 1199861 3430533 NTHI1263 Haemophilus influenzae 86-028NP hypothetical protein YP_248766.1 1199553 D 281310 CDS YP_248767.2 161761269 3430534 complement(1199866..1201878) 1 NC_007146.2 polydeoxyribonucleotide synthase; this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1201878 ligA 3430534 ligA Haemophilus influenzae 86-028NP NAD-dependent DNA ligase LigA YP_248767.2 1199866 R 281310 CDS YP_248768.1 68249656 3430535 complement(1201990..1202976) 1 NC_007146.2 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 1202976 zipA 3430535 zipA Haemophilus influenzae 86-028NP cell division protein ZipA YP_248768.1 1201990 R 281310 CDS YP_248769.1 68249657 3430536 1203129..1203947 1 NC_007146.2 role in sulfur assimilation; sulfate transport protein CysZ 1203947 cysZ 3430536 cysZ Haemophilus influenzae 86-028NP sulfate transport protein CysZ YP_248769.1 1203129 D 281310 CDS YP_248770.1 68249658 3430537 1204046..1204996 1 NC_007146.2 O-acetylserine sulfhydrylase; O-acetylserine (Thiol)-lyase; CSase; Similar to: HI1103, CYSK_HAEIN; cysteine synthase 1204996 cysK 3430537 cysK Haemophilus influenzae 86-028NP cysteine synthase YP_248770.1 1204046 D 281310 CDS YP_248771.1 68249659 3430539 complement(1206577..1207617) 1 NC_007146.2 Similar to: HI1105, RFAF_HAEIN; ADP-heptose--lipooligosaccharide heptosyltransferase II 1207617 rfaF 3430539 rfaF Haemophilus influenzae 86-028NP ADP-heptose--lipooligosaccharide heptosyltransferase II YP_248771.1 1206577 R 281310 CDS YP_248772.1 68249660 3430540 complement(1207693..1208856) 1 NC_007146.2 Similar to: HI1106, XYLR_HAEIN; xylose operon regulatory protein 1208856 xylR 3430540 xylR Haemophilus influenzae 86-028NP xylose operon regulatory protein YP_248772.1 1207693 R 281310 CDS YP_248773.1 68249661 3430541 complement(1208968..1210374) 1 NC_007146.2 Similar to: HI1107, YB07_HAEIN; Na(+)/H(+) antiporter 1210374 3430541 NTHI1274 Haemophilus influenzae 86-028NP Na(+)/H(+) antiporter YP_248773.1 1208968 R 281310 CDS YP_248774.1 68249662 3430542 complement(1210376..1211548) 1 NC_007146.2 Similar to: PATB_BACSU; aspartate aminotransferase 1211548 aspC2 3430542 aspC2 Haemophilus influenzae 86-028NP aspartate aminotransferase YP_248774.1 1210376 R 281310 CDS YP_248775.1 68249663 3430543 1211761..1213080 1 NC_007146.2 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 1213080 xylA 3430543 xylA Haemophilus influenzae 86-028NP xylose isomerase YP_248775.1 1211761 D 281310 CDS YP_248776.1 68249664 3430544 1213083..1214618 1 NC_007146.2 xylulokinase; Similar to: HI1113, XYLB_HAEIN; xylulose kinase 1214618 xylB 3430544 xylB Haemophilus influenzae 86-028NP xylulose kinase YP_248776.1 1213083 D 281310 CDS YP_248777.1 68249665 3430545 complement(1214669..1215595) 1 NC_007146.2 ADP-glyceromanno-heptose 6-epimerase; catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 1215595 rfaD 3430545 rfaD Haemophilus influenzae 86-028NP ADP-L-glycero-D-manno-heptose-6-epimerase YP_248777.1 1214669 R 281310 CDS YP_248778.1 68249666 3430546 complement(1215648..1216151) 1 NC_007146.2 Similar to: HI1115, THIX_HAEIN; thioredoxin-like protein 1216151 3430546 NTHI1279 Haemophilus influenzae 86-028NP thioredoxin-like protein YP_248778.1 1215648 R 281310 CDS YP_248779.1 68249667 3430547 1216262..1216933 1 NC_007146.2 phosphodeoxyriboaldolase; deoxyriboaldolase; DERA; catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 1216933 deoC 3430547 deoC Haemophilus influenzae 86-028NP deoxyribose-phosphate aldolase YP_248779.1 1216262 D 281310 CDS YP_248780.1 68249668 3430548 complement(1216967..1218496) 1 NC_007146.2 Similar to: HI1117, COMM_HAEIN; competence protein ComM 1218496 comM 3430548 comM Haemophilus influenzae 86-028NP competence protein ComM YP_248780.1 1216967 R 281310 CDS YP_248781.1 68249669 3430549 complement(1218611..1219228) 1 NC_007146.2 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1219228 engB 3430549 engB Haemophilus influenzae 86-028NP ribosome biogenesis GTP-binding protein YsxC YP_248781.1 1218611 R 281310 CDS YP_248782.1 68249670 3430550 1219321..1220199 1 NC_007146.2 Similar to: HI1119, YB19_HAEIN; D-xylose transport permease protein 1220199 3430550 NTHI1285 Haemophilus influenzae 86-028NP D-xylose transport permease protein YP_248782.1 1219321 D 281310 CDS YP_248783.1 68249671 3430551 complement(1220239..1221237) 1 NC_007146.2 Similar to: HI1120, OPPF_HAEIN; oligopeptide transport ATP-binding protein 1221237 oppF 3430551 oppF Haemophilus influenzae 86-028NP oligopeptide transport ATP-binding protein YP_248783.1 1220239 R 281310 CDS YP_248784.1 68249672 3430552 complement(1221234..1222205) 1 NC_007146.2 Similar to: HI1121, OPPD_HAEIN; oligopeptide transporter ATP-binding protein 1222205 oppD 3430552 oppD Haemophilus influenzae 86-028NP oligopeptide transporter ATP-binding protein YP_248784.1 1221234 R 281310 CDS YP_248785.1 68249673 3430553 complement(1222215..1223150) 1 NC_007146.2 Similar to: HI1122, OPPC_HAEIN; oligopeptide transport system permease protein 1223150 oppC 3430553 oppC Haemophilus influenzae 86-028NP oligopeptide transport system permease protein YP_248785.1 1222215 R 281310 CDS YP_248786.1 68249674 3430554 complement(1223160..1224080) 1 NC_007146.2 Similar to: HI1123, OPPB_HAEIN; oligopeptide transporter permease 1224080 oppB 3430554 oppB Haemophilus influenzae 86-028NP oligopeptide transporter permease YP_248786.1 1223160 R 281310 CDS YP_248787.1 68249675 3430555 complement(1224161..1225786) 1 NC_007146.2 Similar to: HI1124, OPPA_HAEIN; periplasmic oligopeptide-binding protein 1225786 oppA 3430555 oppA Haemophilus influenzae 86-028NP periplasmic oligopeptide-binding protein YP_248787.1 1224161 R 281310 CDS YP_248788.1 68249676 3430556 1226081..1227034 1 NC_007146.2 Maintains the balance of metabolites in the pentose-phosphate pathway; transaldolase B 1227034 talB 3430556 talB Haemophilus influenzae 86-028NP transaldolase B YP_248788.1 1226081 D 281310 CDS YP_248789.1 68249677 3430557 1228095..1229696 1 NC_007146.2 Similar to: HI1126.1, YB2X_HAEIN; carbon starvation protein, membrane protein 1229696 3430557 NTHI1295 Haemophilus influenzae 86-028NP carbon starvation protein, membrane protein YP_248789.1 1228095 D 281310 CDS YP_248790.1 68249678 3430558 1229898..1230353 1 NC_007146.2 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 1230353 mraZ 3430558 mraZ Haemophilus influenzae 86-028NP cell division protein MraZ YP_248790.1 1229898 D 281310 CDS YP_248791.1 68249679 3430559 1230384..1231349 1 NC_007146.2 Similar to: HI1130, MRAW_HAEIN; S-adenosyl-methyltransferase MraW 1231349 mraW 3430559 mraW Haemophilus influenzae 86-028NP S-adenosyl-methyltransferase MraW YP_248791.1 1230384 D 281310 CDS YP_248792.1 68249680 3430560 1231352..1231675 1 NC_007146.2 Similar to: HI1131, FTSL_HAEIN; cell division protein FtsL 1231675 ftsL 3430560 ftsL Haemophilus influenzae 86-028NP cell division protein FtsL YP_248792.1 1231352 D 281310 CDS YP_248793.1 68249681 3430561 1231688..1233520 1 NC_007146.2 peptidoglycan glycosyltransferase 3; penicillin-binding protein 3; PBP-3; Similar to: HI1132, FTSI_HAEIN; peptidoglycan synthetase FtsI 1233520 ftsI 3430561 ftsI Haemophilus influenzae 86-028NP peptidoglycan synthetase FtsI YP_248793.1 1231688 D 281310 CDS YP_248794.1 68249682 3430562 1233530..1234996 1 NC_007146.2 UDP-N-acetylmuramyl-tripeptide synthetase; Meso-diaminopimelate-adding enzyme; UDP-MurNAc-tripeptide synthetase; involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1234996 murE 3430562 murE Haemophilus influenzae 86-028NP UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_248794.1 1233530 D 281310 CDS YP_248795.1 68249683 3430563 1235010..1236383 1 NC_007146.2 UDP-MurNAc-pentapeptide synthetase; D-alanyl-D-alanine-adding enzyme; Similar to: HI1134, MURF_HAEIN; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 1236383 murF 3430563 murF Haemophilus influenzae 86-028NP UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_248795.1 1235010 D 281310 CDS YP_248796.1 68249684 3430564 1236377..1237459 1 NC_007146.2 UDP-MurNAc-pentapeptide phosphotransferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1237459 mraY 3430564 mraY Haemophilus influenzae 86-028NP phospho-N-acetylmuramoyl-pentapeptide- transferase YP_248796.1 1236377 D 281310 CDS YP_248797.1 68249685 3430565 1237571..1238884 1 NC_007146.2 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; D-glutamic acid adding enzyme; UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 1238884 murD 3430565 murD Haemophilus influenzae 86-028NP UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_248797.1 1237571 D 281310 CDS YP_248798.1 68249686 3430566 1238907..1240091 1 NC_007146.2 Similar to: HI1137, FTSW_HAEIN; cell division protein FtsW 1240091 ftsW 3430566 ftsW Haemophilus influenzae 86-028NP cell division protein FtsW YP_248798.1 1238907 D 281310 CDS YP_248799.1 68249687 3430567 1240103..1241158 1 NC_007146.2 pentapeptide; undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1241158 murG 3430567 murG Haemophilus influenzae 86-028NP undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_248799.1 1240103 D 281310 CDS YP_248800.1 68249688 3430568 1241296..1242723 1 NC_007146.2 UDP-N-acetylmuramoyl-L-alanine synthetase; Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1242723 murC 3430568 murC Haemophilus influenzae 86-028NP UDP-N-acetylmuramate--L-alanine ligase YP_248800.1 1241296 D 281310 CDS YP_248801.1 68249689 3430569 1242792..1243712 1 NC_007146.2 D-alanylalanine synthetase; D-Ala-D-Ala ligase; D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 1243712 ddl 3430569 ddl Haemophilus influenzae 86-028NP D-alanine--D-alanine ligase YP_248801.1 1242792 D 281310 CDS YP_248802.1 68249690 3430570 1243712..1244476 1 NC_007146.2 Similar to: HI1141, FTSQ_HAEIN; cell division protein FtsQ 1244476 ftsQ 3430570 ftsQ Haemophilus influenzae 86-028NP cell division protein FtsQ YP_248802.1 1243712 D 281310 CDS YP_248803.1 68249691 3430571 1244495..1245772 1 NC_007146.2 Similar to: HI1142, FTSA_HAEIN; cell division protein FtsA 1245772 ftsA 3430571 ftsA Haemophilus influenzae 86-028NP cell division protein FtsA YP_248803.1 1244495 D 281310 CDS YP_248804.1 68249692 3430572 1245856..1247121 1 NC_007146.2 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1247121 ftsZ 3430572 ftsZ Haemophilus influenzae 86-028NP cell division protein FtsZ YP_248804.1 1245856 D 281310 CDS YP_248805.1 68249693 3430573 1247160..1248077 1 NC_007146.2 UDP-3-O-acyl-GlcNAc deacetylase; zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 1248077 lpxC 3430573 lpxC Haemophilus influenzae 86-028NP UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_248805.1 1247160 D 281310 CDS YP_248806.1 68249694 3430574 1248204..1249361 1 NC_007146.2 CM; PDT; Similar to: HI1145, PHEA_HAEIN; P-protein 1249361 pheA 3430574 pheA Haemophilus influenzae 86-028NP P-protein YP_248806.1 1248204 D 281310 CDS YP_248807.1 68249695 3430575 complement(1249406..1250263) 1 NC_007146.2 Similar to: HI1146, YB46_HAEIN; hypothetical protein 1250263 3430575 NTHI1314 Haemophilus influenzae 86-028NP hypothetical protein YP_248807.1 1249406 R 281310 CDS YP_248808.1 68249696 3430576 complement(1250281..1250775) 1 NC_007146.2 Similar to: HI1147, PTSN_HAEIN; nitrogen regulatory IIA protein 1250775 ptsN 3430576 ptsN Haemophilus influenzae 86-028NP nitrogen regulatory IIA protein YP_248808.1 1250281 R 281310 CDS YP_248809.1 68249697 3430577 complement(1250778..1251503) 1 NC_007146.2 Similar to: HI1148, YHBG_HAEIN; ABC transporter ATP-binding protein 1251503 3430577 NTHI1316 Haemophilus influenzae 86-028NP ABC transporter ATP-binding protein YP_248809.1 1250778 R 281310 CDS YP_248810.1 68249698 3430578 complement(1251507..1252025) 1 NC_007146.2 Similar to: HI1149, YHBN_HAEIN; hypothetical protein 1252025 3430578 NTHI1317 Haemophilus influenzae 86-028NP hypothetical protein YP_248810.1 1251507 R 281310 CDS YP_248811.1 68249699 3430579 complement(1252006..1252614) 1 NC_007146.2 Similar to: HI1150, YRBK_HAEIN; hypothetical protein 1252614 3430579 NTHI1318 Haemophilus influenzae 86-028NP hypothetical protein YP_248811.1 1252006 R 281310 CDS YP_248812.1 68249700 3430580 complement(1252664..1253200) 1 NC_007146.2 Similar to: HI1151, YJGA_HAEIN; hypothetical protein 1253200 3430580 NTHI1319 Haemophilus influenzae 86-028NP hypothetical protein YP_248812.1 1252664 R 281310 CDS YP_248813.1 68249701 3430581 1253289..1254644 1 NC_007146.2 Similar to: HI1152, PMBA_HAEIN; hypothetical protein 1254644 pmbA 3430581 pmbA Haemophilus influenzae 86-028NP hypothetical protein YP_248813.1 1253289 D 281310 CDS YP_248814.1 68249702 3430582 1255019..1255558 1 NC_007146.2 HPRT; Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 1255558 hpt 3430582 hpt Haemophilus influenzae 86-028NP hypoxanthine-guanine phosphoribosyltransferase YP_248814.1 1255019 D 281310 CDS YP_248815.1 68249703 3430583 1255864..1257186 1 NC_007146.2 Similar to: HI1154, YDJN_HAEIN; Na+/dicarboxylate symporter 1257186 3430583 NTHI1323 Haemophilus influenzae 86-028NP Na+/dicarboxylate symporter YP_248815.1 1255864 D 281310 CDS YP_248816.1 68249704 3430584 complement(1257286..1257753) 1 NC_007146.2 Class III anaerobic ribonucleotide reductase small component; activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 1257753 nrdG 3430584 nrdG Haemophilus influenzae 86-028NP anaerobic ribonucleotide reductase-activating protein YP_248816.1 1257286 R 281310 CDS YP_248817.1 68249705 3430585 complement(1258001..1259731) 1 NC_007146.2 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component 1259731 cydC 3430585 cydC Haemophilus influenzae 86-028NP cysteine/glutathione ABC transporter membrane/ATP-binding component YP_248817.1 1258001 R 281310 CDS YP_248818.1 68249706 3430586 complement(1259731..1261491) 1 NC_007146.2 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component 1261491 cydD 3430586 cydD Haemophilus influenzae 86-028NP cysteine/glutathione ABC transporter membrane/ATP-binding component YP_248818.1 1259731 R 281310 CDS YP_248819.1 68249707 3430587 complement(1261563..1262519) 1 NC_007146.2 TRXR; Similar to: HI1158, TRXB_HAEIN; thioredoxin reductase 1262519 trxB 3430587 trxB Haemophilus influenzae 86-028NP thioredoxin reductase YP_248819.1 1261563 R 281310 CDS YP_248820.1 68249708 3430588 complement(1262593..1263450) 1 NC_007146.2 Similar to: HI1159, YBBN_HAEIN; thioredoxin 1263450 3430588 NTHI1328 Haemophilus influenzae 86-028NP thioredoxin YP_248820.1 1262593 R 281310 CDS YP_248821.1 68249709 3430589 complement(1263529..1264500) 1 NC_007146.2 protoheme ferro-lyase; heme synthetase; protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1264500 hemH 3430589 hemH Haemophilus influenzae 86-028NP ferrochelatase YP_248821.1 1263529 R 281310 CDS YP_248822.1 68249710 3430590 complement(1264497..1264913) 1 NC_007146.2 Similar to: HI1161, YB61_HAEIN; hypothetical protein 1264913 3430590 NTHI1330 Haemophilus influenzae 86-028NP hypothetical protein YP_248822.1 1264497 R 281310 CDS YP_248823.1 68249711 3430591 complement(1264927..1268010) 1 NC_007146.2 Similar to: HI1163, YDIJ_HAEIN; hypothetical protein 1268010 3430591 NTHI1331 Haemophilus influenzae 86-028NP hypothetical protein YP_248823.1 1264927 R 281310 CDS YP_248824.1 68249712 3430592 1268385..1269464 1 NC_007146.2 OMP P5-homologous adhesin; Similar to: HI1164, OM53_HAEIN; outer membrane protein P5 1269464 ompP5 3430592 ompP5 Haemophilus influenzae 86-028NP outer membrane protein P5 YP_248824.1 1268385 D 281310 CDS YP_248825.1 68249713 3430593 1269576..1269938 1 NC_007146.2 Similar to: HI1165, YDHD_HAEIN; glutaredoxin-like protein 1269938 3430593 NTHI1333 Haemophilus influenzae 86-028NP glutaredoxin-like protein YP_248825.1 1269576 D 281310 CDS YP_248826.1 68249714 3430594 complement(1270015..1271115) 1 NC_007146.2 imidazole acetol-phosphate transaminase 2; catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1271115 3430594 NTHI1334 Haemophilus influenzae 86-028NP histidinol-phosphate aminotransferase YP_248826.1 1270015 R 281310 CDS YP_248827.1 68249715 3430595 complement(1271203..1272291) 1 NC_007146.2 PSAT; catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1272291 serC 3430595 serC Haemophilus influenzae 86-028NP phosphoserine aminotransferase YP_248827.1 1271203 R 281310 CDS YP_248828.1 68249716 3430596 1272482..1272826 1 NC_007146.2 Similar to: HI1168, YB68_HAEIN; hypothetical protein 1272826 3430596 NTHI1336 Haemophilus influenzae 86-028NP hypothetical protein YP_248828.1 1272482 D 281310 CDS YP_248829.1 68249717 3430597 complement(1272866..1273432) 1 NC_007146.2 Similar to: HI1169, YB69_HAEIN; hypothetical protein 1273432 3430597 NTHI1337 Haemophilus influenzae 86-028NP hypothetical protein YP_248829.1 1272866 R 281310 CDS YP_248830.1 68249718 3430598 complement(1273432..1274418) 1 NC_007146.2 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; para-aminobenzoate synthase component I 1274418 3430598 NTHI1338 Haemophilus influenzae 86-028NP para-aminobenzoate synthase component I YP_248830.1 1273432 R 281310 CDS YP_248831.1 68249719 3430599 1274460..1275041 1 NC_007146.2 glutamine amido-transferase; catalyzes the formation of anthranilate from chorismate and glutamine; functions in tryptophan biosynthesis; anthranilate synthase component II 1275041 trpG2 3430599 trpG2 Haemophilus influenzae 86-028NP anthranilate synthase component II YP_248831.1 1274460 D 281310 CDS YP_248832.1 68249720 3430600 1275126..1276280 1 NC_007146.2 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1276280 metK 3430600 metK Haemophilus influenzae 86-028NP S-adenosylmethionine synthetase YP_248832.1 1275126 D 281310 CDS YP_248833.1 68249721 3430601 1276575..1277090 1 NC_007146.2 Similar to: HI1173, SPRT_HAEIN; hypothetical protein 1277090 sprT 3430601 sprT Haemophilus influenzae 86-028NP hypothetical protein YP_248833.1 1276575 D 281310 CDS YP_248834.1 68249722 3430602 1277141..1277653 1 NC_007146.2 Similar to: HI1174, OPA_HAEIN; opacity protein 1277653 opa 3430602 opa Haemophilus influenzae 86-028NP opacity protein YP_248834.1 1277141 D 281310 CDS YP_248835.1 68249723 3430603 complement(1277689..1277994) 1 NC_007146.2 Similar to: HI1176; hypothetical protein 1277994 3430603 NTHI1344 Haemophilus influenzae 86-028NP hypothetical protein YP_248835.1 1277689 R 281310 CDS YP_248836.1 68249724 3430604 complement(1278201..1278884) 1 NC_007146.2 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 1278884 artM 3430604 artM Haemophilus influenzae 86-028NP arginine transporter permease subunit ArtM YP_248836.1 1278201 R 281310 CDS YP_248837.1 68249725 3430605 complement(1278884..1279549) 1 NC_007146.2 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 1279549 artQ 3430605 artQ Haemophilus influenzae 86-028NP arginine transporter permease subunit ArtQ YP_248837.1 1278884 R 281310 CDS YP_248838.1 68249726 3430606 complement(1279553..1280272) 1 NC_007146.2 Similar to: HI1179, ARTI_HAEIN; arginine-binding periplasmic protein 1280272 artI 3430606 artI Haemophilus influenzae 86-028NP arginine-binding periplasmic protein YP_248838.1 1279553 R 281310 CDS YP_248839.1 68249727 3430607 complement(1280290..1281021) 1 NC_007146.2 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 1281021 artP 3430607 artP Haemophilus influenzae 86-028NP arginine transporter ATP-binding subunit YP_248839.1 1280290 R 281310 CDS YP_248840.1 68249728 3430608 complement(1281147..1281731) 1 NC_007146.2 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 1281731 gmhA 3430608 gmhA Haemophilus influenzae 86-028NP phosphoheptose isomerase YP_248840.1 1281147 R 281310 CDS YP_248841.1 68249729 3430609 1281831..1282745 1 NC_007146.2 polydeoxyribonucleotide synthase; catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA; DNA ligase 1282745 ligA 3430609 ligA Haemophilus influenzae 86-028NP DNA ligase YP_248841.1 1281831 D 281310 CDS YP_248842.1 68249730 3430610 complement(1282774..1283757) 1 NC_007146.2 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 1283757 dppF 3430610 dppF Haemophilus influenzae 86-028NP dipeptide transporter ATP-binding subunit YP_248842.1 1282774 R 281310 CDS YP_248843.1 68249731 3430611 complement(1283760..1284752) 1 NC_007146.2 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 1284752 dppD 3430611 dppD Haemophilus influenzae 86-028NP dipeptide transporter ATP-binding subunit YP_248843.1 1283760 R 281310 CDS YP_248844.1 68249732 3430612 complement(1284762..1285649) 1 NC_007146.2 Similar to: HI1186, DPPC_HAEIN; dipeptide transport system permease protein 1285649 dppC 3430612 dppC Haemophilus influenzae 86-028NP dipeptide transport system permease protein YP_248844.1 1284762 R 281310 CDS YP_248845.1 68249733 3430613 complement(1285664..1286665) 1 NC_007146.2 Similar to: HI1187, DPPB_HAEIN; dipeptide transport system permease protein 1286665 dppB 3430613 dppB Haemophilus influenzae 86-028NP dipeptide transport system permease protein YP_248845.1 1285664 R 281310 CDS YP_248846.1 68249734 3430614 complement(1286755..1288938) 1 NC_007146.2 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 1288938 uvrD 3430614 uvrD Haemophilus influenzae 86-028NP DNA-dependent helicase II YP_248846.1 1286755 R 281310 CDS YP_248847.1 68249735 3430615 complement(1289545..1290180) 1 NC_007146.2 Similar to: HI1189, YGCF_HAEIN; organic radical activating protein 1290180 3430615 NTHI1360 Haemophilus influenzae 86-028NP organic radical activating protein YP_248847.1 1289545 R 281310 CDS YP_248848.1 68249736 3430616 complement(1290181..1290606) 1 NC_007146.2 Similar to: HI1190, YB90_HAEIN; 6-pyruvoyl tetrahydrobiopterin synthase 1290606 3430616 NTHI1361 Haemophilus influenzae 86-028NP 6-pyruvoyl tetrahydrobiopterin synthase YP_248848.1 1290181 R 281310 CDS YP_248849.1 68249737 3430617 complement(1290599..1291282) 1 NC_007146.2 Similar to: HI1191, YBAX_HAEIN; PP-loop superfamily ATPase 1291282 3430617 NTHI1362 Haemophilus influenzae 86-028NP PP-loop superfamily ATPase YP_248849.1 1290599 R 281310 CDS YP_248850.1 68249738 3430618 1291438..1291581 1 NC_007146.2 Similar to: HI1192, YB92_HAEIN; hypothetical protein 1291581 3430618 NTHI1363 Haemophilus influenzae 86-028NP hypothetical protein YP_248850.1 1291438 D 281310 CDS YP_248851.1 68249739 3430619 complement(1291632..1292663) 1 NC_007146.2 BCAT; catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1292663 ilvE 3430619 ilvE Haemophilus influenzae 86-028NP branched-chain amino acid aminotransferase YP_248851.1 1291632 R 281310 CDS YP_248852.1 68249740 3430620 1293138..1294031 1 NC_007146.2 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 1294031 gcvA 3430620 gcvA Haemophilus influenzae 86-028NP DNA-binding transcriptional activator GcvA YP_248852.1 1293138 D 281310 CDS YP_248853.1 68249741 3430621 1294024..1295115 1 NC_007146.2 Similar to: HI1195, YGDE_HAEIN; RNA 2'-O-ribose methyltransferase 1295115 3430621 NTHI1366 Haemophilus influenzae 86-028NP RNA 2'-O-ribose methyltransferase YP_248853.1 1294024 D 281310 CDS YP_248854.1 68249742 3430622 1295151..1296320 1 NC_007146.2 SCS-beta; catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1296320 sucC 3430622 sucC Haemophilus influenzae 86-028NP succinyl-CoA synthetase subunit beta YP_248854.1 1295151 D 281310 CDS YP_248855.1 68249743 3430623 1296320..1297201 1 NC_007146.2 SCS-alpha; Similar to: HI1197, SUCD_HAEIN; succinyl-CoA synthetase alpha chain 1297201 sucD 3430623 sucD Haemophilus influenzae 86-028NP succinyl-CoA synthetase alpha chain YP_248855.1 1296320 D 281310 CDS YP_248856.1 68249744 3430624 1297322..1297945 1 NC_007146.2 Similar to: HI1198, YCIO_HAEIN; hypothetical protein 1297945 3430624 NTHI1369 Haemophilus influenzae 86-028NP hypothetical protein YP_248856.1 1297322 D 281310 CDS YP_248857.1 68249745 3430625 1297993..1299066 1 NC_007146.2 pseudouridylate synthase; Uracil hydrolyase; Similar to: HI1199, RLUB_HAEIN; ribosomal large subunit pseudouridine synthase B 1299066 rluB 3430625 rluB Haemophilus influenzae 86-028NP ribosomal large subunit pseudouridine synthase B YP_248857.1 1297993 D 281310 CDS YP_248858.1 68249746 3430626 1299077..1300048 1 NC_007146.2 Cys regulon transcriptional activator; LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1300048 cysB 3430626 cysB Haemophilus influenzae 86-028NP transcriptional regulator CysB YP_248858.1 1299077 D 281310 CDS YP_248859.1 68249747 3430627 complement(1300107..1301051) 1 NC_007146.2 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1301051 3430627 NTHI1372 Haemophilus influenzae 86-028NP N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_248859.1 1300107 R 281310 CDS YP_248860.1 68249748 3430628 1301182..1301685 1 NC_007146.2 Similar to: HI1202, YC02_HAEIN; hypothetical protein 1301685 3430628 NTHI1373 Haemophilus influenzae 86-028NP hypothetical protein YP_248860.1 1301182 D 281310 CDS YP_248861.1 68249749 3430629 complement(1301763..1303898) 1 NC_007146.2 phosphotransacetylase; catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 1303898 pta 3430629 pta Haemophilus influenzae 86-028NP phosphate acetyltransferase YP_248861.1 1301763 R 281310 CDS YP_248862.1 68249750 3430630 complement(1303966..1305171) 1 NC_007146.2 acetokinase; AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1305171 ackA 3430630 ackA Haemophilus influenzae 86-028NP acetate kinase YP_248862.1 1303966 R 281310 CDS YP_248863.1 68249751 3430631 1305388..1305831 1 NC_007146.2 Similar to: HI1205, YC05_HAEIN; hypothetical protein 1305831 3430631 NTHI1376 Haemophilus influenzae 86-028NP hypothetical protein YP_248863.1 1305388 D 281310 CDS YP_248864.1 68249752 3430632 1305918..1306409 1 NC_007146.2 Similar to: HI1206, CVPA_HAEIN; colicin V production protein 1306409 cvpA 3430632 cvpA Haemophilus influenzae 86-028NP colicin V production protein YP_248864.1 1305918 D 281310 CDS YP_248865.1 68249753 3430633 1306420..1307937 1 NC_007146.2 glutamine phosphoribosylpyrophosphate amidotransferase; ATASE; GPATase; Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1307937 purF 3430633 purF Haemophilus influenzae 86-028NP amidophosphoribosyltransferase YP_248865.1 1306420 D 281310 CDS YP_248866.1 68249754 3430634 complement(1308002..1308892) 1 NC_007146.2 Similar to: HI1208, YFCH_HAEIN; cell division inhibitor SulA 1308892 sulA 3430634 sulA Haemophilus influenzae 86-028NP cell division inhibitor SulA YP_248866.1 1308002 R 281310 CDS YP_248867.1 68249755 3430635 complement(1308892..1309347) 1 NC_007146.2 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 1309347 argR 3430635 argR Haemophilus influenzae 86-028NP arginine repressor ArgR YP_248867.1 1308892 R 281310 CDS YP_248868.1 68249756 3430636 1309554..1310489 1 NC_007146.2 oxidizes malate to oxaloacetate; malate dehydrogenase 1310489 mdh 3430636 mdh Haemophilus influenzae 86-028NP malate dehydrogenase YP_248868.1 1309554 D 281310 CDS YP_248869.1 68249757 3430637 complement(1310576..1312084) 1 NC_007146.2 Lysine--tRNA ligase; LysRS; class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 1312084 lysS 3430637 lysS Haemophilus influenzae 86-028NP lysyl-tRNA synthetase YP_248869.1 1310576 R 281310 CDS YP_248870.1 68249758 3430638 complement(1312196..1313047) 1 NC_007146.2 RF-2; Similar to: HI1561, RF2_HAEIN; peptide chain release factor 2 1313047 prfB 3430638 prfB Haemophilus influenzae 86-028NP peptide chain release factor 2 YP_248870.1 1312196 R 281310 CDS YP_248871.1 68249759 3430639 1313427..1314116 1 NC_007146.2 Similar to: HI1213, DSBC_HAEIN; thiol-disulfide interchange protein 1314116 dsbC 3430639 dsbC Haemophilus influenzae 86-028NP thiol-disulfide interchange protein YP_248871.1 1313427 D 281310 CDS YP_248872.1 68249760 3430640 1314404..1316131 1 NC_007146.2 Similar to: HI1214, RECJ_HAEIN; single-stranded-DNA-specific exonuclease RecJ 1316131 recJ 3430640 recJ Haemophilus influenzae 86-028NP single-stranded-DNA-specific exonuclease RecJ YP_248872.1 1314404 D 281310 CDS YP_248873.1 68249761 3430641 1316124..1316831 1 NC_007146.2 Similar to: HI1215, YC15_HAEIN; hypothetical protein 1316831 3430641 NTHI1387 Haemophilus influenzae 86-028NP hypothetical protein YP_248873.1 1316124 D 281310 CDS YP_248874.1 68249762 3430642 1316828..1317520 1 NC_007146.2 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1317520 mtnA 3430642 mtnA Haemophilus influenzae 86-028NP 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_248874.1 1316828 D 281310 CDS YP_248875.1 68249763 3430643 complement(1317594..1320341) 1 NC_007146.2 Similar to: HI1217, YC17_HAEIN; heme utilization protein 1320341 hup 3430643 hup Haemophilus influenzae 86-028NP heme utilization protein YP_248875.1 1317594 R 281310 CDS YP_248876.1 68249764 3430644 complement(1320641..1322239) 1 NC_007146.2 Similar to: HI1218, YC18_HAEIN; L-lactate permease 1322239 3430644 NTHI1391 Haemophilus influenzae 86-028NP L-lactate permease YP_248876.1 1320641 R 281310 CDS YP_248877.1 68249765 3430646 complement(1322643..1323647) 1 NC_007146.2 D-fructose-1,6-bisphosphate 1-phosphohydrolase; FBPase; catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 1323647 fbp 3430646 fbp Haemophilus influenzae 86-028NP fructose-1,6-bisphosphatase YP_248877.1 1322643 R 281310 CDS YP_248878.1 68249766 3430647 1323882..1324691 1 NC_007146.2 pseudouridylate synthase I; pseudouridine synthase I; Uracil hydrolyase; mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1324691 truA 3430647 truA Haemophilus influenzae 86-028NP tRNA pseudouridine synthase A YP_248878.1 1323882 D 281310 CDS YP_248879.1 68249767 3430648 complement(1324784..1325800) 1 NC_007146.2 Similar to: HI1643, YEIH_HAEIN; hypothetical protein 1325800 sapZ 3430648 sapZ Haemophilus influenzae 86-028NP hypothetical protein YP_248879.1 1324784 R 281310 CDS YP_248880.1 68249768 3430649 complement(1325812..1326621) 1 NC_007146.2 Similar to: HI1642, SAPF_HAEIN; anti peptide resistance ABC transporter ATPase 1326621 sapF 3430649 sapF Haemophilus influenzae 86-028NP anti peptide resistance ABC transporter ATPase YP_248880.1 1325812 R 281310 CDS YP_248881.1 68249769 3430650 complement(1326621..1327670) 1 NC_007146.2 Similar to: HI1641, SAPD_HAEIN; peptide ABC transporter ATP-binding protein 1327670 sapD 3430650 sapD Haemophilus influenzae 86-028NP peptide ABC transporter ATP-binding protein YP_248881.1 1326621 R 281310 CDS YP_248882.1 68249770 3430651 complement(1327674..1328561) 1 NC_007146.2 Similar to: HI1640, SAPC_HAEIN; ABC transporter permease 1328561 sapC 3430651 sapC Haemophilus influenzae 86-028NP ABC transporter permease YP_248882.1 1327674 R 281310 CDS YP_248883.1 68249771 3430652 complement(1328551..1329516) 1 NC_007146.2 Similar to: HI1639, SAPB_HAEIN; ABC transporter permease 1329516 sapB 3430652 sapB Haemophilus influenzae 86-028NP ABC transporter permease YP_248883.1 1328551 R 281310 CDS YP_248884.1 68249772 3430653 complement(1329516..1331210) 1 NC_007146.2 Similar to: HI1638, SAPA_HAEIN; anti peptide resistance ABC transporter periplasmic protein 1331210 sapA 3430653 sapA Haemophilus influenzae 86-028NP anti peptide resistance ABC transporter periplasmic protein YP_248884.1 1329516 R 281310 CDS YP_248885.1 68249773 3430654 1331280..1332692 1 NC_007146.2 Similar to: HI1637, YCJX_HAEIN; hypothetical protein 1332692 3430654 NTHI1402 Haemophilus influenzae 86-028NP hypothetical protein YP_248885.1 1331280 D 281310 CDS YP_248886.1 68249774 3430655 complement(1332729..1335368) 1 NC_007146.2 PEPCase; PEPC; catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 1335368 ppc 3430655 ppc Haemophilus influenzae 86-028NP phosphoenolpyruvate carboxylase YP_248886.1 1332729 R 281310 CDS YP_248887.1 68249775 3430656 complement(1335551..1336561) 1 NC_007146.2 Purine nucleotide synthesis repressor; binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1336561 purR 3430656 purR Haemophilus influenzae 86-028NP DNA-binding transcriptional repressor PurR YP_248887.1 1335551 R 281310 CDS YP_248888.2 161761268 3430657 1336924..1337751 1 NC_007146.2 tetrahydrodipicolinate N-succinyltransferase; THP succinyltransferase; tetrahydropicolinate succinylase; catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1337751 dapD 3430657 dapD Haemophilus influenzae 86-028NP 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_248888.2 1336924 D 281310 CDS YP_248889.1 68249777 3430658 complement(1337808..1339106) 1 NC_007146.2 IMP--aspartate ligase; AdSS; AMPSase; catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1339106 purA 3430658 purA Haemophilus influenzae 86-028NP adenylosuccinate synthetase YP_248889.1 1337808 R 281310 CDS YP_248890.1 68249778 3430659 complement(1339235..1339600) 1 NC_007146.2 Similar to: HI1632, YG32_HAEIN; aspartokinase 1339600 3430659 NTHI1408 Haemophilus influenzae 86-028NP aspartokinase YP_248890.1 1339235 R 281310 CDS YP_248891.1 68249779 3430664 complement(1340448..1340735) 1 NC_007146.2 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1340735 rplY 3430664 rplY Haemophilus influenzae 86-028NP 50S ribosomal protein L25 YP_248891.1 1340448 R 281310 CDS YP_248892.1 68249780 3430665 1340903..1341559 1 NC_007146.2 Similar to: HI1629, YG29_HAEIN; membrane-associated protein 1341559 3430665 NTHI1412 Haemophilus influenzae 86-028NP membrane-associated protein YP_248892.1 1340903 D 281310 CDS YP_248893.1 68249781 3430666 complement(1341606..1342022) 1 NC_007146.2 Similar to: HI1628, YHCB_HAEIN; hypothetical protein 1342022 3430666 NTHI1413 Haemophilus influenzae 86-028NP hypothetical protein YP_248893.1 1341606 R 281310 CDS YP_248894.1 68249782 3430667 complement(1342053..1342403) 1 NC_007146.2 Similar to: HI1627, YG27_HAEIN; YjgF family translation initiation inhibitor 1342403 3430667 NTHI1414 Haemophilus influenzae 86-028NP YjgF family translation initiation inhibitor YP_248894.1 1342053 R 281310 CDS YP_248895.1 68249783 3430668 1342515..1343231 1 NC_007146.2 Similar to: HI1626, YG26_HAEIN; hypothetical protein 1343231 3430668 NTHI1415 Haemophilus influenzae 86-028NP hypothetical protein YP_248895.1 1342515 D 281310 CDS YP_248896.1 68249784 3430669 1343232..1343774 1 NC_007146.2 Similar to: HI1625, YG25_HAEIN; hypothetical protein 1343774 3430669 NTHI1416 Haemophilus influenzae 86-028NP hypothetical protein YP_248896.1 1343232 D 281310 CDS YP_248897.1 68249785 3430670 complement(1343789..1344247) 1 NC_007146.2 Similar to: HI1623, ZNTR_HAEIN; HTH-type transcriptional regulator 1344247 3430670 NTHI1417 Haemophilus influenzae 86-028NP HTH-type transcriptional regulator YP_248897.1 1343789 R 281310 CDS YP_248898.1 68249786 3430671 1344286..1344969 1 NC_007146.2 Similar to: HI1624, YG24_HAEIN; ABC-type Co2+ transport system, periplasmic component 1344969 3430671 NTHI1418 Haemophilus influenzae 86-028NP ABC-type Co2+ transport system, periplasmic component YP_248898.1 1344286 D 281310 CDS YP_248899.1 68249787 3430672 1344982..1345470 1 NC_007146.2 Similar to: HI1622, YG22_HAEIN; hypothetical protein 1345470 3430672 NTHI1419 Haemophilus influenzae 86-028NP hypothetical protein YP_248899.1 1344982 D 281310 CDS YP_248900.1 68249788 3430673 1345470..1346090 1 NC_007146.2 catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM 1346090 cbiM 3430673 cbiM Haemophilus influenzae 86-028NP cobalt transport protein CbiM YP_248900.1 1345470 D 281310 CDS YP_248901.1 68249789 3430674 1346090..1346722 1 NC_007146.2 Similar to: HI1620, YG20_HAEIN; cobalt ABC transporter permease 1346722 3430674 NTHI1421 Haemophilus influenzae 86-028NP cobalt ABC transporter permease YP_248901.1 1346090 D 281310 CDS YP_248902.1 68249790 3430675 1346724..1347350 1 NC_007146.2 Similar to: HI1618, YG18_HAEIN; cobalt ABC transporter ATPase 1347350 cbiO 3430675 cbiO Haemophilus influenzae 86-028NP cobalt ABC transporter ATPase YP_248902.1 1346724 D 281310 CDS YP_248903.1 68249791 3430676 complement(1347457..1348647) 1 NC_007146.2 transaminase A; ASPAT; catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1348647 aspC 3430676 aspC Haemophilus influenzae 86-028NP aromatic amino acid aminotransferase YP_248903.1 1347457 R 281310 CDS YP_248904.1 68249792 3430677 complement(1348787..1349875) 1 NC_007146.2 AIR carboxylase; AIRC; With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1349875 purK 3430677 purK Haemophilus influenzae 86-028NP phosphoribosylaminoimidazole carboxylase ATPase subunit YP_248904.1 1348787 R 281310 CDS YP_248905.1 68249793 3430678 complement(1349945..1350439) 1 NC_007146.2 AIR carboxylase; AIRC; Catalyzes a step in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase catalytic subunit 1350439 purE 3430678 purE Haemophilus influenzae 86-028NP phosphoribosylaminoimidazole carboxylase catalytic subunit YP_248905.1 1349945 R 281310 CDS YP_248906.1 68249794 3430679 1350610..1350858 1 NC_007146.2 HicA 1350858 hicA 3430679 hicA Haemophilus influenzae 86-028NP HicA YP_248906.1 1350610 D 281310 CDS YP_248907.1 68249795 3430680 1350855..1351199 1 NC_007146.2 HicB 1351199 hicB 3430680 hicB Haemophilus influenzae 86-028NP HicB YP_248907.1 1350855 D 281310 CDS YP_248908.1 68249796 3430681 1351243..1353852 1 NC_007146.2 alpha-aminoacylpeptide hydrolase; Similar to: HI1614, AMPN_HAEIN; aminopeptidase 1353852 pepN 3430681 pepN Haemophilus influenzae 86-028NP aminopeptidase YP_248908.1 1351243 D 281310 CDS YP_248909.1 68249797 3430682 complement(1353924..1354538) 1 NC_007146.2 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1354538 ribE 3430682 ribE Haemophilus influenzae 86-028NP riboflavin synthase subunit alpha YP_248909.1 1353924 R 281310 CDS YP_248910.1 68249798 3430683 1354582..1355976 1 NC_007146.2 Na(+)/drug antiporter; multidrug-efflux transporter; NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1355976 norM 3430683 norM Haemophilus influenzae 86-028NP multidrug efflux protein YP_248910.1 1354582 D 281310 CDS YP_248911.1 68249799 3430684 1355985..1356701 1 NC_007146.2 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 1356701 sfsA 3430684 sfsA Haemophilus influenzae 86-028NP sugar fermentation stimulation protein A YP_248911.1 1355985 D 281310 CDS YP_248912.1 68249800 3430685 1356901..1358088 1 NC_007146.2 tyrosine--tRNA ligase; TyrRS; catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1358088 tyrS 3430685 tyrS Haemophilus influenzae 86-028NP tyrosyl-tRNA synthetase YP_248912.1 1356901 D 281310 CDS YP_248913.1 68249801 3430686 complement(1358152..1359099) 1 NC_007146.2 RPPK; phosphoribosyl pyrophosphate synthetase; P-Rib-PP synthetase; PRPP synthetase; catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1359099 prsA 3430686 prsA Haemophilus influenzae 86-028NP ribose-phosphate pyrophosphokinase YP_248913.1 1358152 R 281310 CDS YP_248914.1 68249802 3430687 complement(1359101..1360054) 1 NC_007146.2 CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase; An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1360054 ipk 3430687 ipk Haemophilus influenzae 86-028NP 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_248914.1 1359101 R 281310 CDS YP_248915.1 68249803 3430688 complement(1360054..1360683) 1 NC_007146.2 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB 1360683 lolB 3430688 lolB Haemophilus influenzae 86-028NP molecular chaperone LolB YP_248915.1 1360054 R 281310 CDS YP_248916.1 68249804 3430689 complement(1360746..1361996) 1 NC_007146.2 tRNA adenylyltransferase; tRNA CCA-pyrophosphorylase; CCA-adding enzyme; catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 1361996 cca 3430689 cca Haemophilus influenzae 86-028NP multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_248916.1 1360746 R 281310 CDS YP_248917.1 68249805 3430690 complement(1362003..1362614) 1 NC_007146.2 Similar to: HI1605, YGIM_HAEIN; hypothetical protein 1362614 3430690 NTHI1437 Haemophilus influenzae 86-028NP hypothetical protein YP_248917.1 1362003 R 281310 CDS YP_248918.1 68249806 3430691 complement(1362680..1363942) 1 NC_007146.2 Similar to: HI1604, YG04_HAEIN; phosphate permease 1363942 3430691 NTHI1438 Haemophilus influenzae 86-028NP phosphate permease YP_248918.1 1362680 R 281310 CDS YP_248919.1 68249807 3430692 complement(1363967..1364647) 1 NC_007146.2 Similar to: HI1603, YG03_HAEIN; phosphate transport regulator 1364647 3430692 NTHI1439 Haemophilus influenzae 86-028NP phosphate transport regulator YP_248919.1 1363967 R 281310 CDS YP_248920.1 68249808 3430693 1364855..1365310 1 NC_007146.2 Similar to: HI1602, YG02_HAEIN; hypothetical protein 1365310 3430693 NTHI1440 Haemophilus influenzae 86-028NP hypothetical protein YP_248920.1 1364855 D 281310 CDS YP_248921.1 68249809 3430694 1365349..1365636 1 NC_007146.2 Similar to: HI1601, YG01_HAEIN; hypothetical protein 1365636 3430694 NTHI1441 Haemophilus influenzae 86-028NP hypothetical protein YP_248921.1 1365349 D 281310 CDS YP_248922.1 68249810 3430695 1365666..1366619 1 NC_007146.2 Similar to: HI1600, YG00_HAEIN; hypothetical protein 1366619 3430695 NTHI1443 Haemophilus influenzae 86-028NP hypothetical protein YP_248922.1 1365666 D 281310 CDS YP_248923.1 68249811 3430696 1366609..1367325 1 NC_007146.2 Similar to: HI1599, YF99_HAEIN; hypothetical protein 1367325 3430696 NTHI1444 Haemophilus influenzae 86-028NP hypothetical protein YP_248923.1 1366609 D 281310 CDS YP_248924.1 68249812 3430697 1368433..1368600 1 NC_007146.2 hypothetical protein 1368600 3430697 NTHI1445 Haemophilus influenzae 86-028NP hypothetical protein YP_248924.1 1368433 D 281310 CDS YP_248925.1 68249813 3430698 1368998..1369114 1 NC_007146.2 hypothetical protein 1369114 3430698 NTHI1446 Haemophilus influenzae 86-028NP hypothetical protein YP_248925.1 1368998 D 281310 CDS YP_248926.1 68249814 3430699 complement(1369564..1369728) 1 NC_007146.2 hypothetical protein 1369728 3430699 NTHI1447 Haemophilus influenzae 86-028NP hypothetical protein YP_248926.1 1369564 R 281310 CDS YP_248927.1 68249815 3430700 complement(1369918..1371870) 1 NC_007146.2 HMW2C, glycosyltransferase involved in glycosylation of HMW1A and HMW2A 1371870 hmw2C 3430700 hmw2C Haemophilus influenzae 86-028NP HMW2C, glycosyltransferase involved in glycosylation of HMW1A and HMW2A YP_248927.1 1369918 R 281310 CDS YP_248928.1 68249816 3430701 complement(1372262..1373899) 1 NC_007146.2 HMW2B, OMP-85-like protein required for HMW1A and HMW2A secretion 1373899 hmw2B 3430701 hmw2B Haemophilus influenzae 86-028NP HMW2B, OMP-85-like protein required for HMW1A and HMW2A secretion YP_248928.1 1372262 R 281310 CDS YP_248929.1 68249817 3430702 complement(1374050..1378678) 1 NC_007146.2 HMW2A, high molecular weight adhesin 2 1378678 hmw2A 3430702 hmw2A Haemophilus influenzae 86-028NP HMW2A, high molecular weight adhesin 2 YP_248929.1 1374050 R 281310 CDS YP_248930.1 68249818 3430703 1379103..1380149 1 NC_007146.2 Similar to: HI1598, YGIF_HAEIN; hypothetical protein 1380149 3430703 NTHI1451 Haemophilus influenzae 86-028NP hypothetical protein YP_248930.1 1379103 D 281310 CDS YP_248931.1 68249819 3430704 1380382..1381758 1 NC_007146.2 DNA repair protein sms homolog; Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 1381758 radA 3430704 radA Haemophilus influenzae 86-028NP DNA repair protein RadA YP_248931.1 1380382 D 281310 CDS YP_248932.2 161761267 3430705 1381838..1382317 1 NC_007146.2 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 1382317 lrp 3430705 lrp Haemophilus influenzae 86-028NP leucine-responsive transcriptional regulator YP_248932.2 1381838 D 281310 CDS YP_248933.1 68249821 3430706 1382319..1385075 1 NC_007146.2 Similar to: HI1592, FTSK_HAEIN; DNA translocase FtsK 1385075 ftsK 3430706 ftsK Haemophilus influenzae 86-028NP DNA translocase FtsK YP_248933.1 1382319 D 281310 CDS YP_248934.1 68249822 3430707 1385093..1385710 1 NC_007146.2 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1385710 lolA 3430707 lolA Haemophilus influenzae 86-028NP outer-membrane lipoprotein carrier protein YP_248934.1 1385093 D 281310 CDS YP_248935.1 68249823 3430708 1385771..1387111 1 NC_007146.2 Similar to: HI1590, YCAJ_HAEIN; recombination factor protein RarA 1387111 3430708 NTHI1458 Haemophilus influenzae 86-028NP recombination factor protein RarA YP_248935.1 1385771 D 281310 CDS YP_248936.1 68249824 3430709 complement(1387199..1388341) 1 NC_007146.2 hypothetical protein 1388341 3430709 NTHI1459 Haemophilus influenzae 86-028NP hypothetical protein YP_248936.1 1387199 R 281310 CDS YP_248937.1 68249825 3430710 complement(1388351..1389574) 1 NC_007146.2 cytosine-specific methyltransferase BepI-like; Similar to: MTB1_BREEP; modification methylase BepI-like 1389574 3430710 NTHI1460 Haemophilus influenzae 86-028NP modification methylase BepI-like YP_248937.1 1388351 R 281310 CDS YP_248938.1 68249826 3430711 complement(1389829..1391127) 1 NC_007146.2 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS; catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1391127 aroA 3430711 aroA Haemophilus influenzae 86-028NP 3-phosphoshikimate 1-carboxyvinyltransferase YP_248938.1 1389829 R 281310 CDS YP_248939.1 68249827 3430712 complement(1391127..1391963) 1 NC_007146.2 Formyl-FH(4) hydrolase; produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1391963 purU 3430712 purU Haemophilus influenzae 86-028NP formyltetrahydrofolate deformylase YP_248939.1 1391127 R 281310 CDS YP_248940.1 68249828 3430713 complement(1392033..1392437) 1 NC_007146.2 Similar to: HI1587, HNS_HAEIN; DNA-binding protein H-NS-like protein 1392437 hns 3430713 hns Haemophilus influenzae 86-028NP DNA-binding protein H-NS-like protein YP_248940.1 1392033 R 281310 CDS YP_248941.1 68249829 3430714 1392841..1394400 1 NC_007146.2 Similar to: HI1586, YF86_HAEIN; Na+/H+ antiporter 1394400 3430714 NTHI1465 Haemophilus influenzae 86-028NP Na+/H+ antiporter YP_248941.1 1392841 D 281310 CDS YP_248942.1 68249830 3430715 1394468..1394617 1 NC_007146.2 hypothetical protein 1394617 3430715 NTHI1466 Haemophilus influenzae 86-028NP hypothetical protein YP_248942.1 1394468 D 281310 CDS YP_248943.1 68249831 3430716 1394667..1396388 1 NC_007146.2 AHAS; acetohydroxy-acid synthase large subunit; ALS; acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 3 catalytic subunit 1396388 ilvI 3430716 ilvI Haemophilus influenzae 86-028NP acetolactate synthase 3 catalytic subunit YP_248943.1 1394667 D 281310 CDS YP_248944.1 68249832 3430717 1396388..1396879 1 NC_007146.2 AHAS; acetohydroxy-acid synthase small subunit; ALS; with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1396879 ilvH 3430717 ilvH Haemophilus influenzae 86-028NP acetolactate synthase 3 regulatory subunit YP_248944.1 1396388 D 281310 CDS YP_248945.1 68249833 3430718 complement(1397173..1398906) 1 NC_007146.2 arginine--tRNA ligase; ArgRS; catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1398906 argS 3430718 argS Haemophilus influenzae 86-028NP arginyl-tRNA synthetase YP_248945.1 1397173 R 281310 CDS YP_248946.1 68249834 3430719 1398986..1399555 1 NC_007146.2 Similar to: HI1582, YECM_HAEIN; hypothetical protein 1399555 3430719 NTHI1471 Haemophilus influenzae 86-028NP hypothetical protein YP_248946.1 1398986 D 281310 CDS YP_248947.1 68249835 3430720 1399634..1399855 1 NC_007146.2 lipoprotein 1399855 3430720 NTHI1472 Haemophilus influenzae 86-028NP lipoprotein YP_248947.1 1399634 D 281310 CDS YP_248948.1 68249836 3430721 1399878..1400342 1 NC_007146.2 15 kDa lipoprotein; PAL cross-reacting lipoprotein; Similar to: HI1579, PCP_HAEIN; outer membrane lipoprotein PCP 1400342 pcp 3430721 pcp Haemophilus influenzae 86-028NP outer membrane lipoprotein PCP YP_248948.1 1399878 D 281310 CDS YP_248949.1 68249837 3430722 complement(1400526..1401497) 1 NC_007146.2 Similar to: HI1578, YF78_HAEIN; UDP-GlcNAc--lipooligosaccharide N-acetylglucosamine glycosyltransferase 1401497 lgtD 3430722 lgtD Haemophilus influenzae 86-028NP UDP-GlcNAc--lipooligosaccharide N-acetylglucosamine glycosyltransferase YP_248949.1 1400526 R 281310 CDS YP_248950.2 161761266 3430724 complement(1402135..1403784) 1 NC_007146.2 GPI; phosphoglucose isomerase; PGI; phosphohexose isomerase; PHI; functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1403784 pgi 3430724 pgi Haemophilus influenzae 86-028NP glucose-6-phosphate isomerase YP_248950.2 1402135 R 281310 CDS YP_248951.1 68249839 3430725 complement(1403881..1404963) 1 NC_007146.2 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1404963 alr 3430725 alr Haemophilus influenzae 86-028NP alanine racemase YP_248951.1 1403881 R 281310 CDS YP_248952.1 68249840 3430726 complement(1404973..1406487) 1 NC_007146.2 unwinds double stranded DNA; replicative DNA helicase 1406487 dnaB 3430726 dnaB Haemophilus influenzae 86-028NP replicative DNA helicase YP_248952.1 1404973 R 281310 CDS YP_248953.1 68249841 3430727 complement(1406521..1407957) 1 NC_007146.2 PK; catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1407957 pykA 3430727 pykA Haemophilus influenzae 86-028NP pyruvate kinase YP_248953.1 1406521 R 281310 CDS YP_248954.1 68249842 3430729 1408494..1409753 1 NC_007146.2 Similar to: INTA_ECOLI; prophage CP4-57-like integrase 1409753 3430729 NTHI1480 Haemophilus influenzae 86-028NP prophage CP4-57-like integrase YP_248954.1 1408494 D 281310 CDS YP_248955.1 68249843 3430730 complement(1410367..1410636) 1 NC_007146.2 hypothetical protein 1410636 3430730 NTHI1482 Haemophilus influenzae 86-028NP hypothetical protein YP_248955.1 1410367 R 281310 CDS YP_248956.1 68249844 3430731 complement(1410741..1410911) 1 NC_007146.2 hypothetical protein 1410911 3430731 NTHI1483 Haemophilus influenzae 86-028NP hypothetical protein YP_248956.1 1410741 R 281310 CDS YP_248957.1 68249845 3430732 complement(1410901..1411434) 1 NC_007146.2 hypothetical protein 1411434 3430732 NTHI1484 Haemophilus influenzae 86-028NP hypothetical protein YP_248957.1 1410901 R 281310 CDS YP_248958.1 68249846 3430733 complement(1411506..1411922) 1 NC_007146.2 hypothetical protein 1411922 3430733 NTHI1485 Haemophilus influenzae 86-028NP hypothetical protein YP_248958.1 1411506 R 281310 CDS YP_248959.1 68249847 3430734 complement(1411926..1412603) 1 NC_007146.2 hypothetical protein 1412603 3430734 NTHI1486 Haemophilus influenzae 86-028NP hypothetical protein YP_248959.1 1411926 R 281310 CDS YP_248960.1 68249848 3430735 complement(1412622..1413785) 1 NC_007146.2 cytosine-specific methyltransferase Bsp6I-like; modification methylase Bsp6I-like 1413785 3430735 NTHI1487 Haemophilus influenzae 86-028NP modification methylase Bsp6I-like YP_248960.1 1412622 R 281310 CDS YP_248961.1 68249849 3430736 complement(1414391..1415287) 1 NC_007146.2 Required for efficient pilin antigenic variation; recombination associated protein 1415287 rdgC 3430736 rdgC Haemophilus influenzae 86-028NP recombination associated protein YP_248961.1 1414391 R 281310 CDS YP_248962.1 68249850 3430737 complement(1415412..1416758) 1 NC_007146.2 hypothetical protein 1416758 3430737 NTHI1489 Haemophilus influenzae 86-028NP hypothetical protein YP_248962.1 1415412 R 281310 CDS YP_248963.1 68249851 3430738 complement(1416820..1417254) 1 NC_007146.2 SSB; Helix-destabilizing protein; single-strand binding protein 1417254 ssb3 3430738 ssb3 Haemophilus influenzae 86-028NP single-strand binding protein YP_248963.1 1416820 R 281310 CDS YP_248964.1 68249852 3430739 complement(1417254..1417898) 1 NC_007146.2 hypothetical protein 1417898 3430739 NTHI1491 Haemophilus influenzae 86-028NP hypothetical protein YP_248964.1 1417254 R 281310 CDS YP_248965.1 68249853 3430740 complement(1417879..1418799) 1 NC_007146.2 Similar to: YQAK_BACSU; recombinational DNA repair protein, RecE pathway 1418799 3430740 NTHI1492 Haemophilus influenzae 86-028NP recombinational DNA repair protein, RecE pathway YP_248965.1 1417879 R 281310 CDS YP_248966.1 68249854 3430741 complement(1418812..1419105) 1 NC_007146.2 hypothetical protein 1419105 3430741 NTHI1493 Haemophilus influenzae 86-028NP hypothetical protein YP_248966.1 1418812 R 281310 CDS YP_248967.1 68249855 3430742 complement(1419102..1419446) 1 NC_007146.2 hypothetical protein 1419446 3430742 NTHI1494 Haemophilus influenzae 86-028NP hypothetical protein YP_248967.1 1419102 R 281310 CDS YP_248968.1 68249856 3430743 complement(1419460..1420197) 1 NC_007146.2 adenine-specific methyltransferase DpnIIB-like; modification methylase DpnIIB-like 1420197 3430743 NTHI1495 Haemophilus influenzae 86-028NP modification methylase DpnIIB-like YP_248968.1 1419460 R 281310 CDS YP_248969.1 68249857 3430744 complement(1420288..1421319) 1 NC_007146.2 hypothetical protein 1421319 3430744 NTHI1497 Haemophilus influenzae 86-028NP hypothetical protein YP_248969.1 1420288 R 281310 CDS YP_248970.1 68249858 3430745 complement(1421309..1421560) 1 NC_007146.2 hypothetical protein 1421560 3430745 NTHI1498 Haemophilus influenzae 86-028NP hypothetical protein YP_248970.1 1421309 R 281310 CDS YP_248971.1 68249859 3430746 complement(1421679..1421990) 1 NC_007146.2 hypothetical protein 1421990 3430746 NTHI1499 Haemophilus influenzae 86-028NP hypothetical protein YP_248971.1 1421679 R 281310 CDS YP_248972.1 68249860 3430747 complement(1422376..1422561) 1 NC_007146.2 hypothetical protein 1422561 3430747 NTHI1501 Haemophilus influenzae 86-028NP hypothetical protein YP_248972.1 1422376 R 281310 CDS YP_248973.1 68249861 3430748 complement(1422722..1423870) 1 NC_007146.2 hypothetical protein 1423870 3430748 NTHI1502 Haemophilus influenzae 86-028NP hypothetical protein YP_248973.1 1422722 R 281310 CDS YP_248974.1 68249862 3430749 complement(1423881..1424741) 1 NC_007146.2 hypothetical protein 1424741 3430749 NTHI1503 Haemophilus influenzae 86-028NP hypothetical protein YP_248974.1 1423881 R 281310 CDS YP_248975.1 68249863 3430750 complement(1424804..1425169) 1 NC_007146.2 hypothetical protein 1425169 3430750 NTHI1504 Haemophilus influenzae 86-028NP hypothetical protein YP_248975.1 1424804 R 281310 CDS YP_248976.1 68249864 3430751 complement(1425171..1425758) 1 NC_007146.2 hypothetical protein 1425758 3430751 NTHI1505 Haemophilus influenzae 86-028NP hypothetical protein YP_248976.1 1425171 R 281310 CDS YP_248977.1 68249865 3430752 1425914..1426099 1 NC_007146.2 hypothetical protein 1426099 3430752 NTHI1507 Haemophilus influenzae 86-028NP hypothetical protein YP_248977.1 1425914 D 281310 CDS YP_248978.1 68249866 3430753 1426130..1426558 1 NC_007146.2 hypothetical protein 1426558 3430753 NTHI1508 Haemophilus influenzae 86-028NP hypothetical protein YP_248978.1 1426130 D 281310 CDS YP_248979.1 68249867 3430754 complement(1426559..1427068) 1 NC_007146.2 hypothetical protein 1427068 3430754 NTHI1509 Haemophilus influenzae 86-028NP hypothetical protein YP_248979.1 1426559 R 281310 CDS YP_248980.1 68249868 3430755 complement(1427073..1427663) 1 NC_007146.2 hypothetical protein 1427663 3430755 NTHI1510 Haemophilus influenzae 86-028NP hypothetical protein YP_248980.1 1427073 R 281310 CDS YP_248981.1 68249869 3430756 complement(1427660..1428295) 1 NC_007146.2 hypothetical protein 1428295 3430756 NTHI1511 Haemophilus influenzae 86-028NP hypothetical protein YP_248981.1 1427660 R 281310 CDS YP_248982.1 68249870 3430757 complement(1428280..1429062) 1 NC_007146.2 hypothetical protein 1429062 3430757 NTHI1512 Haemophilus influenzae 86-028NP hypothetical protein YP_248982.1 1428280 R 281310 CDS YP_248983.1 68249871 3430758 complement(1429064..1429297) 1 NC_007146.2 hypothetical protein 1429297 3430758 NTHI1513 Haemophilus influenzae 86-028NP hypothetical protein YP_248983.1 1429064 R 281310 CDS YP_248984.1 68249872 3430759 complement(1429343..1429795) 1 NC_007146.2 hypothetical protein 1429795 3430759 NTHI1515 Haemophilus influenzae 86-028NP hypothetical protein YP_248984.1 1429343 R 281310 CDS YP_248985.1 68249873 3430760 complement(1429839..1430045) 1 NC_007146.2 hypothetical protein 1430045 3430760 NTHI1516 Haemophilus influenzae 86-028NP hypothetical protein YP_248985.1 1429839 R 281310 CDS YP_248986.1 68249874 3430761 1430179..1431147 1 NC_007146.2 hypothetical protein 1431147 3430761 NTHI1517 Haemophilus influenzae 86-028NP hypothetical protein YP_248986.1 1430179 D 281310 CDS YP_248987.1 68249875 3430762 1431341..1431667 1 NC_007146.2 hypothetical protein 1431667 3430762 NTHI1518 Haemophilus influenzae 86-028NP hypothetical protein YP_248987.1 1431341 D 281310 CDS YP_248988.1 68249876 3430763 1431654..1432058 1 NC_007146.2 hypothetical protein 1432058 3430763 NTHI1519 Haemophilus influenzae 86-028NP hypothetical protein YP_248988.1 1431654 D 281310 CDS YP_248989.1 68249877 3430764 1432055..1432444 1 NC_007146.2 hypothetical protein 1432444 3430764 NTHI1520 Haemophilus influenzae 86-028NP hypothetical protein YP_248989.1 1432055 D 281310 CDS YP_248990.1 68249878 3430765 1432419..1432649 1 NC_007146.2 hypothetical protein 1432649 3430765 NTHI1521 Haemophilus influenzae 86-028NP hypothetical protein YP_248990.1 1432419 D 281310 CDS YP_248991.1 68249879 3430766 1432658..1433617 1 NC_007146.2 hypothetical protein 1433617 3430766 NTHI1522 Haemophilus influenzae 86-028NP hypothetical protein YP_248991.1 1432658 D 281310 CDS YP_248992.1 68249880 3430767 1433596..1434015 1 NC_007146.2 DNA modification methylase 1434015 3430767 NTHI1523 Haemophilus influenzae 86-028NP DNA modification methylase YP_248992.1 1433596 D 281310 CDS YP_248993.1 68249881 3430768 complement(1434012..1434233) 1 NC_007146.2 hypothetical protein 1434233 3430768 NTHI1525 Haemophilus influenzae 86-028NP hypothetical protein YP_248993.1 1434012 R 281310 CDS YP_248994.1 68249882 3430769 1434291..1434659 1 NC_007146.2 hypothetical protein 1434659 3430769 NTHI1526 Haemophilus influenzae 86-028NP hypothetical protein YP_248994.1 1434291 D 281310 CDS YP_248995.1 68249883 3430770 1434673..1435989 1 NC_007146.2 Similar to: HI1410, YE10_HAEIN; phage terminase large subunit 1435989 3430770 NTHI1527 Haemophilus influenzae 86-028NP phage terminase large subunit YP_248995.1 1434673 D 281310 CDS YP_248996.1 68249884 3430771 1435991..1437307 1 NC_007146.2 hypothetical protein 1437307 3430771 NTHI1528 Haemophilus influenzae 86-028NP hypothetical protein YP_248996.1 1435991 D 281310 CDS YP_248997.1 68249885 3430772 1437237..1438049 1 NC_007146.2 Similar to: HI1407; phage Mu protein gp30-like protein 1438049 3430772 NTHI1529 Haemophilus influenzae 86-028NP phage Mu protein gp30-like protein YP_248997.1 1437237 D 281310 CDS YP_248998.1 68249886 3430773 1438055..1439128 1 NC_007146.2 hypothetical protein 1439128 3430773 NTHI1530 Haemophilus influenzae 86-028NP hypothetical protein YP_248998.1 1438055 D 281310 CDS YP_248999.1 68249887 3430774 1439142..1439561 1 NC_007146.2 hypothetical protein 1439561 3430774 NTHI1531 Haemophilus influenzae 86-028NP hypothetical protein YP_248999.1 1439142 D 281310 CDS YP_249000.1 68249888 3430775 1439569..1440570 1 NC_007146.2 hypothetical protein 1440570 3430775 NTHI1532 Haemophilus influenzae 86-028NP hypothetical protein YP_249000.1 1439569 D 281310 CDS YP_249001.1 68249889 3430776 1440573..1440761 1 NC_007146.2 hypothetical protein 1440761 3430776 NTHI1533 Haemophilus influenzae 86-028NP hypothetical protein YP_249001.1 1440573 D 281310 CDS YP_249002.1 68249890 3430777 1440765..1441115 1 NC_007146.2 hypothetical protein 1441115 3430777 NTHI1534 Haemophilus influenzae 86-028NP hypothetical protein YP_249002.1 1440765 D 281310 CDS YP_249003.1 68249891 3430778 1441108..1441566 1 NC_007146.2 hypothetical protein 1441566 3430778 NTHI1535 Haemophilus influenzae 86-028NP hypothetical protein YP_249003.1 1441108 D 281310 CDS YP_249004.1 68249892 3430779 1441566..1441925 1 NC_007146.2 hypothetical protein 1441925 3430779 NTHI1536 Haemophilus influenzae 86-028NP hypothetical protein YP_249004.1 1441566 D 281310 CDS YP_249005.1 68249893 3430780 1441927..1442436 1 NC_007146.2 hypothetical protein 1442436 3430780 NTHI1537 Haemophilus influenzae 86-028NP hypothetical protein YP_249005.1 1441927 D 281310 CDS YP_249006.1 68249894 3430781 1442423..1443496 1 NC_007146.2 hypothetical protein 1443496 3430781 NTHI1538 Haemophilus influenzae 86-028NP hypothetical protein YP_249006.1 1442423 D 281310 CDS YP_249007.1 68249895 3430782 1443542..1443967 1 NC_007146.2 hypothetical protein 1443967 3430782 NTHI1539 Haemophilus influenzae 86-028NP hypothetical protein YP_249007.1 1443542 D 281310 CDS YP_249008.1 68249896 3430783 1443967..1444449 1 NC_007146.2 hypothetical protein 1444449 3430783 NTHI1540 Haemophilus influenzae 86-028NP hypothetical protein YP_249008.1 1443967 D 281310 CDS YP_249009.1 68249897 3430784 1444485..1444637 1 NC_007146.2 hypothetical protein 1444637 3430784 NTHI1541 Haemophilus influenzae 86-028NP hypothetical protein YP_249009.1 1444485 D 281310 CDS YP_249010.1 68249898 3430785 1444634..1447051 1 NC_007146.2 phage-like minor tail protein 1447051 3430785 NTHI1542 Haemophilus influenzae 86-028NP phage-like minor tail protein YP_249010.1 1444634 D 281310 CDS YP_249011.1 68249899 3430786 complement(1447126..1447698) 1 NC_007146.2 hypothetical protein 1447698 3430786 NTHI1543 Haemophilus influenzae 86-028NP hypothetical protein YP_249011.1 1447126 R 281310 CDS YP_249012.1 68249900 3430787 1448006..1448587 1 NC_007146.2 hypothetical protein 1448587 3430787 NTHI1544 Haemophilus influenzae 86-028NP hypothetical protein YP_249012.1 1448006 D 281310 CDS YP_249013.1 68249901 3430788 1448584..1448898 1 NC_007146.2 hypothetical protein 1448898 3430788 NTHI1546 Haemophilus influenzae 86-028NP hypothetical protein YP_249013.1 1448584 D 281310 CDS YP_249014.1 68249902 3430789 1448895..1449851 1 NC_007146.2 hypothetical protein 1449851 3430789 NTHI1547 Haemophilus influenzae 86-028NP hypothetical protein YP_249014.1 1448895 D 281310 CDS YP_249015.1 68249903 3430790 1449854..1450525 1 NC_007146.2 hypothetical protein 1450525 3430790 NTHI1548 Haemophilus influenzae 86-028NP hypothetical protein YP_249015.1 1449854 D 281310 CDS YP_249016.1 68249904 3430791 1450522..1450887 1 NC_007146.2 hypothetical protein 1450887 3430791 NTHI1549 Haemophilus influenzae 86-028NP hypothetical protein YP_249016.1 1450522 D 281310 CDS YP_249017.1 68249905 3430792 1450880..1452316 1 NC_007146.2 hypothetical protein 1452316 3430792 NTHI1550 Haemophilus influenzae 86-028NP hypothetical protein YP_249017.1 1450880 D 281310 CDS YP_249018.1 68249906 3430793 1452325..1452939 1 NC_007146.2 hypothetical protein 1452939 3430793 NTHI1551 Haemophilus influenzae 86-028NP hypothetical protein YP_249018.1 1452325 D 281310 CDS YP_249019.1 68249907 3430794 1452949..1455297 1 NC_007146.2 Similar to: HI1403, VPH_BPHP1; tail fiber protein 1455297 3430794 NTHI1552 Haemophilus influenzae 86-028NP tail fiber protein YP_249019.1 1452949 D 281310 CDS YP_249020.1 68249908 3430795 1455309..1455911 1 NC_007146.2 Similar to: YO32_BPHP1; hypothetical protein 1455911 3430795 NTHI1553 Haemophilus influenzae 86-028NP hypothetical protein YP_249020.1 1455309 D 281310 CDS YP_249021.1 68249909 3430796 1455908..1456408 1 NC_007146.2 hypothetical protein 1456408 3430796 NTHI1554 Haemophilus influenzae 86-028NP hypothetical protein YP_249021.1 1455908 D 281310 CDS YP_249022.1 68249910 3430797 1456474..1456923 1 NC_007146.2 Similar to: HI1523, YF23_HAEIN; hypothetical protein 1456923 3430797 NTHI1555 Haemophilus influenzae 86-028NP hypothetical protein YP_249022.1 1456474 D 281310 CDS YP_249023.1 68249911 3430798 complement(1456962..1457225) 1 NC_007146.2 hypothetical protein 1457225 3430798 NTHI1556 Haemophilus influenzae 86-028NP hypothetical protein YP_249023.1 1456962 R 281310 CDS YP_249024.1 68249912 3430800 complement(1459009..1459290) 1 NC_007146.2 hypothetical protein 1459290 3430800 NTHI1560 Haemophilus influenzae 86-028NP hypothetical protein YP_249024.1 1459009 R 281310 CDS YP_249025.1 68249913 3430801 1459338..1459523 1 NC_007146.2 Similar to: HI1571, YF71_HAEIN; hypothetical protein 1459523 3430801 NTHI1561 Haemophilus influenzae 86-028NP hypothetical protein YP_249025.1 1459338 D 281310 CDS YP_249026.1 68249914 3430802 1459583..1460251 1 NC_007146.2 Similar to: HI1570, YF70_HAEIN; hypothetical protein 1460251 3430802 NTHI1562 Haemophilus influenzae 86-028NP hypothetical protein YP_249026.1 1459583 D 281310 CDS YP_249027.1 68249915 3430803 1460353..1460499 1 NC_007146.2 hypothetical protein 1460499 3430803 NTHI1563 Haemophilus influenzae 86-028NP hypothetical protein YP_249027.1 1460353 D 281310 CDS YP_249028.1 68249916 3430804 1460532..1461068 1 NC_007146.2 Similar to: HI1563, YFCM_HAEIN; hypothetical protein 1461068 3430804 NTHI1564 Haemophilus influenzae 86-028NP hypothetical protein YP_249028.1 1460532 D 281310 CDS YP_249029.1 68249917 3430805 1461269..1461715 1 NC_007146.2 hypothetical protein 1461715 3430805 NTHI1565 Haemophilus influenzae 86-028NP hypothetical protein YP_249029.1 1461269 D 281310 CDS YP_249030.1 68249918 3430806 1461715..1461891 1 NC_007146.2 hypothetical protein 1461891 3430806 NTHI1566 Haemophilus influenzae 86-028NP hypothetical protein YP_249030.1 1461715 D 281310 CDS YP_249031.1 68249919 3430807 1461903..1462562 1 NC_007146.2 Similar to: YBEQ_ECOLI; hypothetical protein 1462562 3430807 NTHI1567 Haemophilus influenzae 86-028NP hypothetical protein YP_249031.1 1461903 D 281310 CDS YP_249032.1 68249920 3430808 1462562..1462738 1 NC_007146.2 hypothetical protein 1462738 3430808 NTHI1568 Haemophilus influenzae 86-028NP hypothetical protein YP_249032.1 1462562 D 281310 CDS YP_249033.1 68249921 3430809 1462751..1463305 1 NC_007146.2 hypothetical protein 1463305 3430809 NTHI1569 Haemophilus influenzae 86-028NP hypothetical protein YP_249033.1 1462751 D 281310 CDS YP_249034.1 68249922 3430810 1463305..1463481 1 NC_007146.2 hypothetical protein 1463481 3430810 NTHI1570 Haemophilus influenzae 86-028NP hypothetical protein YP_249034.1 1463305 D 281310 CDS YP_249035.1 68249923 3430811 1463494..1464045 1 NC_007146.2 hypothetical protein 1464045 3430811 NTHI1571 Haemophilus influenzae 86-028NP hypothetical protein YP_249035.1 1463494 D 281310 CDS YP_249036.1 68249924 3430812 1464321..1465406 1 NC_007146.2 RF-1; recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1465406 prfA 3430812 prfA Haemophilus influenzae 86-028NP peptide chain release factor 1 YP_249036.1 1464321 D 281310 CDS YP_249037.1 68249925 3430813 1465429..1465899 1 NC_007146.2 Similar to: HI1560, YF60_HAEIN; hypothetical protein 1465899 3430813 NTHI1573 Haemophilus influenzae 86-028NP hypothetical protein YP_249037.1 1465429 D 281310 CDS YP_249038.1 68249926 3430814 1465899..1466777 1 NC_007146.2 M.HindHemKP; Similar to: HI1559, HEMK_HAEIN; hypothetical protein 1466777 hemK 3430814 hemK Haemophilus influenzae 86-028NP hypothetical protein YP_249038.1 1465899 D 281310 CDS YP_249039.1 68249927 3430815 1466777..1467580 1 NC_007146.2 Similar to: HI1558, YF58_HAEIN; hypothetical protein 1467580 3430815 NTHI1575 Haemophilus influenzae 86-028NP hypothetical protein YP_249039.1 1466777 D 281310 CDS YP_249040.1 68249928 3430816 1467595..1468449 1 NC_007146.2 phospho-2-dehydro-3-deoxyoctonate aldolase; 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase; KDO-8-phosphate synthetase; KDO 8-P synthase; KDOPS; catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1468449 kdsA 3430816 kdsA Haemophilus influenzae 86-028NP 2-dehydro-3-deoxyphosphooctonate aldolase YP_249040.1 1467595 D 281310 CDS YP_249041.1 68249929 3430817 1468509..1469456 1 NC_007146.2 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; glycerate dehydrogenase 1469456 3430817 NTHI1577 Haemophilus influenzae 86-028NP glycerate dehydrogenase YP_249041.1 1468509 D 281310 CDS YP_249042.1 68249930 3430818 1469456..1470637 1 NC_007146.2 Similar to: HI1555, LOLC_HAEIN; lipoprotein releasing system transmembrane protein 1470637 lolC 3430818 lolC Haemophilus influenzae 86-028NP lipoprotein releasing system transmembrane protein YP_249042.1 1469456 D 281310 CDS YP_249043.1 68249931 3430819 1470649..1471941 1 NC_007146.2 7,8-diamino-pelargonic acid aminotransferase; DAPA aminotransferase; catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 1471941 bioA 3430819 bioA Haemophilus influenzae 86-028NP adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_249043.1 1470649 D 281310 CDS YP_249044.1 68249932 3430820 1471950..1473089 1 NC_007146.2 AONS; 8-amino-7-ketopelargonate synthase; 7-keto-8-amino-pelargonic acid synthetase; 7-KAP synthetase; L-alanine--pimelyl CoA ligase; catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 1473089 bioF 3430820 bioF Haemophilus influenzae 86-028NP 8-amino-7-oxononanoate synthase YP_249044.1 1471950 D 281310 CDS YP_249045.1 68249933 3430821 1473099..1473746 1 NC_007146.2 Similar to: HI1552, YF52_HAEIN; hypothetical protein 1473746 3430821 NTHI1581 Haemophilus influenzae 86-028NP hypothetical protein YP_249045.1 1473099 D 281310 CDS YP_249046.1 68249934 3430822 1473734..1474516 1 NC_007146.2 Similar to: HI1551, BIOC_HAEIN; biotin synthesis protein BioC 1474516 bioC 3430822 bioC Haemophilus influenzae 86-028NP biotin synthesis protein BioC YP_249046.1 1473734 D 281310 CDS YP_249047.1 68249935 3430823 1474526..1475167 1 NC_007146.2 dethiobiotin synthase 2; DTB synthetase 2; DTBS 2; DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1475167 bioD 3430823 bioD Haemophilus influenzae 86-028NP dithiobiotin synthetase YP_249047.1 1474526 D 281310 CDS YP_249048.1 68249936 3430824 1475249..1475932 1 NC_007146.2 Similar to: HI1549, LOLD_HAEIN; lipoprotein releasing system ATP-binding protein LolD 1475932 lolD 3430824 lolD Haemophilus influenzae 86-028NP lipoprotein releasing system ATP-binding protein LolD YP_249048.1 1475249 D 281310 CDS YP_249049.1 68249937 3430825 1475932..1477182 1 NC_007146.2 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1477182 lolE 3430825 lolE Haemophilus influenzae 86-028NP outer membrane-specific lipoprotein transporter subunit LolE YP_249049.1 1475932 D 281310 CDS YP_249050.1 68249938 3430826 1477401..1478489 1 NC_007146.2 phospho-2-keto-3-deoxyheptonate aldolase; DAHP synthetase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1478489 aroG 3430826 aroG Haemophilus influenzae 86-028NP phospho-2-dehydro-3-deoxyheptonate aldolase YP_249050.1 1477401 D 281310 CDS YP_249051.1 68249939 3430827 complement(1478559..1478999) 1 NC_007146.2 Similar to: HI1546, YF46_HAEIN; ImpA 1478999 impA 3430827 impA Haemophilus influenzae 86-028NP ImpA YP_249051.1 1478559 R 281310 CDS YP_249052.1 68249940 3430828 1479284..1480528 1 NC_007146.2 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 1480528 3430828 NTHI1589 Haemophilus influenzae 86-028NP serine/threonine transporter SstT YP_249052.1 1479284 D 281310 CDS YP_249053.1 68249941 3430829 1480650..1481258 1 NC_007146.2 Similar to: HI1544, YF44_HAEIN; NAD(P)H oxidoreductase 1481258 3430829 NTHI1590 Haemophilus influenzae 86-028NP NAD(P)H oxidoreductase YP_249053.1 1480650 D 281310 CDS YP_249054.1 68249942 3430830 1481258..1481812 1 NC_007146.2 Similar to: HI1543, YCDY_HAEIN; component of anaerobic dehydrogenase 1481812 3430830 NTHI1591 Haemophilus influenzae 86-028NP component of anaerobic dehydrogenase YP_249054.1 1481258 D 281310 CDS YP_249055.1 68249943 3430831 complement(1481859..1482413) 1 NC_007146.2 Similar to: HI1542, YDJA_HAEIN; nitroreductase 1482413 3430831 NTHI1592 Haemophilus influenzae 86-028NP nitroreductase YP_249055.1 1481859 R 281310 CDS YP_249056.1 68249944 3430832 1482511..1484358 1 NC_007146.2 endopeptidase IV; Signal peptide peptidase; Similar to: HI1541, SPPA_HAEIN; endopeptidase IV 1484358 sppA 3430832 sppA Haemophilus influenzae 86-028NP endopeptidase IV YP_249056.1 1482511 D 281310 CDS YP_249057.1 68249945 3430833 complement(1484396..1485193) 1 NC_007146.2 Similar to: HI1540, LICD_HAEIN; phosphorylcholine transferase 1485193 licD 3430833 licD Haemophilus influenzae 86-028NP phosphorylcholine transferase YP_249057.1 1484396 R 281310 CDS YP_249058.1 68249946 3430834 complement(1485193..1485894) 1 NC_007146.2 CTP--phosphocholine cytidylyltransferase involved in choline phosphorylation of cell surface lipooligosaccharide epitopes; Similar to: HI1539, LICC_HAEIN; LicC 1485894 licC 3430834 licC Haemophilus influenzae 86-028NP LicC YP_249058.1 1485193 R 281310 CDS YP_249059.1 68249947 3430835 complement(1485891..1486769) 1 NC_007146.2 choline uptake protein; Similar to: HI1538, LICB_HAEIN; LicB 1486769 licB 3430835 licB Haemophilus influenzae 86-028NP LicB YP_249059.1 1485891 R 281310 CDS YP_249060.1 68249948 3430836 complement(1486769..1487728) 1 NC_007146.2 choline kinase involved in LOS biosynthesis; Similar to: HI1537, LIA2_HAEIN; LicA 1487728 licA 3430836 licA Haemophilus influenzae 86-028NP LicA YP_249060.1 1486769 R 281310 CDS YP_249061.1 68249949 3430837 complement(1487816..1489828) 1 NC_007146.2 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 1489828 mnmC 3430837 mnmC Haemophilus influenzae 86-028NP 5-methylaminomethyl-2-thiouridine methyltransferase YP_249061.1 1487816 R 281310 CDS YP_249062.1 68249950 3430838 1489975..1491195 1 NC_007146.2 beta-ketoacyl-ACP synthase I; KAS I; FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1491195 fabB 3430838 fabB Haemophilus influenzae 86-028NP 3-oxoacyl-ACP synthase YP_249062.1 1489975 D 281310 CDS YP_249063.1 68249951 3430839 complement(1491258..1491521) 1 NC_007146.2 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1 1491521 grxA 3430839 grxA Haemophilus influenzae 86-028NP glutaredoxin 1 YP_249063.1 1491258 R 281310 CDS YP_249064.1 68249952 3430840 1491638..1492546 1 NC_007146.2 Similar to: HI1531, RIMK_HAEIN; ribosomal protein S6 modification protein 1492546 rimK 3430840 rimK Haemophilus influenzae 86-028NP ribosomal protein S6 modification protein YP_249064.1 1491638 D 281310 CDS YP_249065.1 68249953 3430841 complement(1492584..1493798) 1 NC_007146.2 glutamate permease; Similar to: HI1530, GLTS_HAEIN; Sodium/glutamate symport carrier protein 1493798 gltS 3430841 gltS Haemophilus influenzae 86-028NP Sodium/glutamate symport carrier protein YP_249065.1 1492584 R 281310 CDS YP_249066.1 68249954 3430842 complement(1493840..1496083) 1 NC_007146.2 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1496083 parC 3430842 parC Haemophilus influenzae 86-028NP DNA topoisomerase IV subunit A YP_249066.1 1493840 R 281310 CDS YP_249067.1 68249955 3430843 complement(1496150..1498048) 1 NC_007146.2 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1498048 parE 3430843 parE Haemophilus influenzae 86-028NP DNA topoisomerase IV subunit B YP_249067.1 1496150 R 281310 CDS YP_249068.1 68249956 3430844 complement(1498122..1499057) 1 NC_007146.2 heat shock protein B; Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1499057 htrB 3430844 htrB Haemophilus influenzae 86-028NP lipid A biosynthesis lauroyl acyltransferase YP_249068.1 1498122 R 281310 CDS YP_249069.1 68249957 3430845 1499154..1500584 1 NC_007146.2 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 1500584 rfaE 3430845 rfaE Haemophilus influenzae 86-028NP bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_249069.1 1499154 D 281310 CDS YP_249070.1 68249958 3430847 complement(1501255..1501611) 1 NC_007146.2 hypothetical protein 1501611 3430847 NTHI1611 Haemophilus influenzae 86-028NP hypothetical protein YP_249070.1 1501255 R 281310 CDS YP_249071.1 68249959 3430848 1501722..1502126 1 NC_007146.2 Similar to: HI1300, UUP1_HAEIN; ABC transporter ATP-binding protein 1502126 uupA2 3430848 uupA2 Haemophilus influenzae 86-028NP ABC transporter ATP-binding protein YP_249071.1 1501722 D 281310 CDS YP_249072.1 68249960 3430849 1502123..1502683 1 NC_007146.2 Similar to: HI1342, UUP2_HAEIN; ABC transporter ATP-binding protein 1502683 uppB 3430849 uppB Haemophilus influenzae 86-028NP ABC transporter ATP-binding protein YP_249072.1 1502123 D 281310 CDS YP_249073.1 68249961 3430850 complement(1502711..1503400) 1 NC_007146.2 Similar to: HI1301, YADF_HAEIN; carbonic anhydrase 1503400 3430850 NTHI1614 Haemophilus influenzae 86-028NP carbonic anhydrase YP_249073.1 1502711 R 281310 CDS YP_249074.2 161761265 3430851 complement(1503476..1504879) 1 NC_007146.2 asparagine--tRNA ligase; AsnRS; catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1504879 asnC 3430851 asnC Haemophilus influenzae 86-028NP asparaginyl-tRNA synthetase YP_249074.2 1503476 R 281310 CDS YP_249075.1 68249963 3430852 1505106..1505579 1 NC_007146.2 DMRL synthase; lumazine synthase; riboflavin synthase beta chain; RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1505579 ribH 3430852 ribH Haemophilus influenzae 86-028NP 6,7-dimethyl-8-ribityllumazine synthase YP_249075.1 1505106 D 281310 CDS YP_249076.1 68249964 3430853 1505583..1506017 1 NC_007146.2 NusB; Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1506017 nusB 3430853 nusB Haemophilus influenzae 86-028NP transcription antitermination protein NusB YP_249076.1 1505583 D 281310 CDS YP_249077.1 68249965 3430854 1506084..1507070 1 NC_007146.2 thiamine-phosphate kinase; Similar to: HI1305, THIL_HAEIN; thiamine-monophosphate kinase 1507070 thiL 3430854 thiL Haemophilus influenzae 86-028NP thiamine-monophosphate kinase YP_249077.1 1506084 D 281310 CDS YP_249078.1 68249966 3430855 1507067..1507558 1 NC_007146.2 Similar to: HI1306, PGPA_HAEIN; phosphatidylglycerophosphatase A 1507558 pgpA 3430855 pgpA Haemophilus influenzae 86-028NP phosphatidylglycerophosphatase A YP_249078.1 1507067 D 281310 CDS YP_249079.1 68249967 3430856 1507558..1508187 1 NC_007146.2 Similar to: HI1307, YD07_HAEIN; threonine efflux protein 1508187 3430856 NTHI1620 Haemophilus influenzae 86-028NP threonine efflux protein YP_249079.1 1507558 D 281310 CDS YP_249080.1 68249968 3430857 1508204..1509016 1 NC_007146.2 DHPR; catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1509016 dapB 3430857 dapB Haemophilus influenzae 86-028NP dihydrodipicolinate reductase YP_249080.1 1508204 D 281310 CDS YP_249081.1 68249969 3430858 complement(1509011..1509259) 1 NC_007146.2 Similar to: HI1309, YFAE_HAEIN; ferredoxin-like protein 1509259 3430858 NTHI1622 Haemophilus influenzae 86-028NP ferredoxin-like protein YP_249081.1 1509011 R 281310 CDS YP_249082.1 68249970 3430859 1509305..1510045 1 NC_007146.2 Similar to: HI1310, YD10_HAEIN; hypothetical protein 1510045 3430859 NTHI1623 Haemophilus influenzae 86-028NP hypothetical protein YP_249082.1 1509305 D 281310 CDS YP_249083.1 68249971 3430860 1510194..1511183 1 NC_007146.2 phenylalanine--tRNA ligase alpha chain; PheRS; catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1511183 pheS 3430860 pheS Haemophilus influenzae 86-028NP phenylalanyl-tRNA synthetase subunit alpha YP_249083.1 1510194 D 281310 CDS YP_249084.1 68249972 3430861 1511217..1513604 1 NC_007146.2 phenylalanine--tRNA ligase beta chain; PheRS; catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1513604 pheT 3430861 pheT Haemophilus influenzae 86-028NP phenylalanyl-tRNA synthetase subunit beta YP_249084.1 1511217 D 281310 CDS YP_249085.1 68249973 3430862 1513606..1513896 1 NC_007146.2 IHF-alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1513896 ihfA 3430862 ihfA Haemophilus influenzae 86-028NP integration host factor subunit alpha YP_249085.1 1513606 D 281310 CDS YP_249086.1 68249974 3430863 1513949..1514434 1 NC_007146.2 Similar to: HI1314, YD14_HAEIN; lipoprotein 1514434 3430863 NTHI1627 Haemophilus influenzae 86-028NP lipoprotein YP_249086.1 1513949 D 281310 CDS YP_249087.1 68249975 3430864 1514443..1515453 1 NC_007146.2 hypothetical protein 1515453 3430864 NTHI1628 Haemophilus influenzae 86-028NP hypothetical protein YP_249087.1 1514443 D 281310 CDS YP_249088.1 68249976 3430865 1515512..1515967 1 NC_007146.2 Similar to: 53DR_BPKV4; 5'(3')-deoxyribonucleotidase 1515967 3430865 NTHI1629 Haemophilus influenzae 86-028NP 5'(3')-deoxyribonucleotidase YP_249088.1 1515512 D 281310 CDS YP_249089.1 68249977 3430866 1515951..1516661 1 NC_007146.2 regulatory protein SIR2 family; Similar to: NPD_ACTAC; NAD-dependent deacetylase 1516661 3430866 NTHI1630 Haemophilus influenzae 86-028NP NAD-dependent deacetylase YP_249089.1 1515951 D 281310 CDS YP_249090.1 68249978 3430867 complement(1516710..1517732) 1 NC_007146.2 hypothetical protein 1517732 3430867 NTHI1631 Haemophilus influenzae 86-028NP hypothetical protein YP_249090.1 1516710 R 281310 CDS YP_249091.1 68249979 3430868 1517927..1518127 1 NC_007146.2 DNA translocase FtsK 1518127 ftsK2 3430868 ftsK2 Haemophilus influenzae 86-028NP DNA translocase FtsK YP_249091.1 1517927 D 281310 CDS YP_249092.1 68249980 3430869 1518124..1518969 1 NC_007146.2 SIR2 family; NAD-dependent deacetylase 1518969 3430869 NTHI1634 Haemophilus influenzae 86-028NP NAD-dependent deacetylase YP_249092.1 1518124 D 281310 CDS YP_249093.1 68249981 3430870 1518969..1519730 1 NC_007146.2 hypothetical protein 1519730 3430870 NTHI1635 Haemophilus influenzae 86-028NP hypothetical protein YP_249093.1 1518969 D 281310 CDS YP_249094.1 68249982 3430871 1519808..1520782 1 NC_007146.2 hypothetical protein 1520782 3430871 NTHI1636 Haemophilus influenzae 86-028NP hypothetical protein YP_249094.1 1519808 D 281310 CDS YP_249095.1 68249983 3430872 1520859..1521026 1 NC_007146.2 hypothetical protein 1521026 3430872 NTHI1637 Haemophilus influenzae 86-028NP hypothetical protein YP_249095.1 1520859 D 281310 CDS YP_249096.1 68249984 3430873 1521196..1522911 1 NC_007146.2 serine/threonine protein phosphatase family protein 1522911 3430873 NTHI1638 Haemophilus influenzae 86-028NP serine/threonine protein phosphatase family protein YP_249096.1 1521196 D 281310 CDS YP_249097.1 68249985 3430874 1522931..1523368 1 NC_007146.2 Similar to: HI1316, YD16_HAEIN; arylsulfatase 1523368 3430874 NTHI1639 Haemophilus influenzae 86-028NP arylsulfatase YP_249097.1 1522931 D 281310 CDS YP_249098.1 68249986 3430875 1523450..1524262 1 NC_007146.2 Similar to: HI1317, YD17_HAEIN; aldose 1-epimerase 1524262 3430875 NTHI1640 Haemophilus influenzae 86-028NP aldose 1-epimerase YP_249098.1 1523450 D 281310 CDS YP_249099.1 68249987 3430876 1524530..1524937 1 NC_007146.2 Similar to: HI1318, IF3_HAEIN; translation initiation factor IF-3 1524937 infC 3430876 infC Haemophilus influenzae 86-028NP translation initiation factor IF-3 YP_249099.1 1524530 D 281310 CDS YP_249100.2 161761264 3430877 1525148..1525345 1 NC_007146.2 Similar to: HI1319, RL35_HAEIN; 50S ribosomal protein L35 1525345 rpmI 3430877 rpmI Haemophilus influenzae 86-028NP 50S ribosomal protein L35 YP_249100.2 1525148 D 281310 CDS YP_249101.1 68249989 3430878 1525411..1525764 1 NC_007146.2 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1525764 rplT 3430878 rplT Haemophilus influenzae 86-028NP 50S ribosomal protein L20 YP_249101.1 1525411 D 281310 CDS YP_249102.1 68249990 3430879 1525877..1529512 1 NC_007146.2 Similar to: HI1321, EX5B_HAEIN; exodeoxyribonuclease V subunit beta 1529512 recB 3430879 recB Haemophilus influenzae 86-028NP exodeoxyribonuclease V subunit beta YP_249102.1 1525877 D 281310 CDS YP_249103.1 68249991 3430880 1529512..1531434 1 NC_007146.2 Similar to: HI1322, EX5A_HAEIN; exodeoxyribonuclease V subunit alpha 1531434 recD 3430880 recD Haemophilus influenzae 86-028NP exodeoxyribonuclease V subunit alpha YP_249103.1 1529512 D 281310 CDS YP_249104.1 68249992 3430881 complement(1531503..1531949) 1 NC_007146.2 Similar to: HI1323, YD23_HAEIN; hypothetical protein 1531949 3430881 NTHI1647 Haemophilus influenzae 86-028NP hypothetical protein YP_249104.1 1531503 R 281310 CDS YP_249105.1 68249993 3430882 1532046..1533851 1 NC_007146.2 Similar to: HI1324, LONH_HAEIN; protease La 1533851 lonB 3430882 lonB Haemophilus influenzae 86-028NP protease La YP_249105.1 1532046 D 281310 CDS YP_249106.1 68249994 3430883 1534020..1534553 1 NC_007146.2 Beta-hydroxydecanoyl thioester dehydrase; catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1534553 fabA 3430883 fabA Haemophilus influenzae 86-028NP 3-hydroxydecanoyl-ACP dehydratase YP_249106.1 1534020 D 281310 CDS YP_249107.1 68249995 3430884 1534789..1535517 1 NC_007146.2 Similar to: HI1326, YD26_HAEIN; hypothetical protein 1535517 3430884 NTHI1650 Haemophilus influenzae 86-028NP hypothetical protein YP_249107.1 1534789 D 281310 CDS YP_249108.1 68249996 3430885 1535514..1535651 1 NC_007146.2 Similar to: HI1327; hypothetical protein 1535651 3430885 NTHI1651 Haemophilus influenzae 86-028NP hypothetical protein YP_249108.1 1535514 D 281310 CDS YP_249109.1 68249997 3430886 1535787..1536056 1 NC_007146.2 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1536056 rpsO 3430886 rpsO Haemophilus influenzae 86-028NP 30S ribosomal protein S15 YP_249109.1 1535787 D 281310 CDS YP_249110.1 68249998 3430887 complement(1536128..1536499) 1 NC_007146.2 Similar to: HI1328.1, YD2A_HAEIN; transposase-like protein 1536499 3430887 NTHI1653 Haemophilus influenzae 86-028NP transposase-like protein YP_249110.1 1536128 R 281310 CDS YP_249111.1 68249999 3430888 complement(1536496..1536612) 1 NC_007146.2 Similar to: HI1329; hypothetical protein 1536612 3430888 NTHI1654 Haemophilus influenzae 86-028NP hypothetical protein YP_249111.1 1536496 R 281310 CDS YP_249112.1 68250000 3430889 complement(1536828..1538267) 1 NC_007146.2 PBP-4; DD-peptidase; DD-carboxypeptidase; DD-endopeptidase; penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase 1538267 dacB 3430889 dacB Haemophilus influenzae 86-028NP D-alanyl-D-alanine carboxypeptidase/endopeptidase YP_249112.1 1536828 R 281310 CDS YP_249113.1 68250001 3430890 1538431..1538907 1 NC_007146.2 transcript cleavage factor greA; necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1538907 greA 3430890 greA Haemophilus influenzae 86-028NP transcription elongation factor GreA YP_249113.1 1538431 D 281310 CDS YP_249114.1 68250002 3430891 complement(1538946..1539245) 1 NC_007146.2 Similar to: HI1333, YHBY_HAEIN; RNA-binding protein 1539245 3430891 NTHI1659 Haemophilus influenzae 86-028NP RNA-binding protein YP_249114.1 1538946 R 281310 CDS YP_249115.1 68250003 3430892 1539372..1540001 1 NC_007146.2 rRNA (uridine-2'-O-)-methyltransferase; 23S rRNA m2U2552 methyltransferase; Cell division protein ftsJ homolog; Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase 1540001 rrmJ 3430892 rrmJ Haemophilus influenzae 86-028NP 23S rRNA methyltransferase YP_249115.1 1539372 D 281310 CDS YP_249116.1 68250004 3430893 1540092..1541999 1 NC_007146.2 Similar to: HI1335, FTH1_HAEIN; cell division protein FtsH-like protein 1541999 ftsH 3430893 ftsH Haemophilus influenzae 86-028NP cell division protein FtsH-like protein YP_249116.1 1540092 D 281310 CDS YP_249117.1 68250005 3430894 1542111..1542941 1 NC_007146.2 DHPS; dihydropteroate pyrophosphorylase; Similar to: HI1464, DHPS_HAEIN; dihydropteroate synthase 1542941 folP 3430894 folP Haemophilus influenzae 86-028NP dihydropteroate synthase YP_249117.1 1542111 D 281310 CDS YP_249118.1 68250006 3430895 1542974..1544311 1 NC_007146.2 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1544311 glmM 3430895 glmM Haemophilus influenzae 86-028NP phosphoglucosamine mutase YP_249118.1 1542974 D 281310 CDS YP_249119.1 68250007 3430896 1544370..1544864 1 NC_007146.2 Similar to: HI1462.2, SIXA_HAEIN; phosphohistidine phosphatase SixA-like protein 1544864 sixA 3430896 sixA Haemophilus influenzae 86-028NP phosphohistidine phosphatase SixA-like protein YP_249119.1 1544370 D 281310 CDS YP_249120.1 68250008 3430897 1545066..1545641 1 NC_007146.2 Similar to: HI1339, YD39_HAEIN; hypothetical protein 1545641 3430897 NTHI1667 Haemophilus influenzae 86-028NP hypothetical protein YP_249120.1 1545066 D 281310 CDS YP_249121.1 68250009 3430898 complement(1545719..1547083) 1 NC_007146.2 Similar to: HI1462, YE62_HAEIN; hypothetical protein 1547083 3430898 NTHI1668 Haemophilus influenzae 86-028NP hypothetical protein YP_249121.1 1545719 R 281310 CDS YP_249122.1 68250010 3430899 1547310..1547450 1 NC_007146.2 hypothetical protein 1547450 3430899 NTHI1669 Haemophilus influenzae 86-028NP hypothetical protein YP_249122.1 1547310 D 281310 CDS YP_249123.1 68250011 3430900 1547444..1547596 1 NC_007146.2 hypothetical protein 1547596 3430900 NTHI1671 Haemophilus influenzae 86-028NP hypothetical protein YP_249123.1 1547444 D 281310 CDS YP_249124.1 68250012 3430902 1547905..1548501 1 NC_007146.2 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 1548501 3430902 NTHI1673 Haemophilus influenzae 86-028NP RNA polymerase sigma factor YP_249124.1 1547905 D 281310 CDS YP_249125.1 68250013 3430903 1548511..1548684 1 NC_007146.2 hypothetical protein 1548684 3430903 NTHI1674 Haemophilus influenzae 86-028NP hypothetical protein YP_249125.1 1548511 D 281310 CDS YP_249126.1 68250014 3430904 complement(1548779..1549681) 1 NC_007146.2 hypothetical protein 1549681 3430904 NTHI1675 Haemophilus influenzae 86-028NP hypothetical protein YP_249126.1 1548779 R 281310 CDS YP_249127.1 68250015 3430905 1549817..1550878 1 NC_007146.2 peptide methionine sulfoxide reductase MsrA; peptide methionine sulfoxide reductase MsrB; protein-methionine-S-oxide reductase; peptide Met(O) reductase; this fusion consists of methionine sulfoxide A reductase at the N-terminus and B at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion; bifunctional methionine sulfoxide reductase A/B protein 1550878 msaB 3430905 msaB Haemophilus influenzae 86-028NP bifunctional methionine sulfoxide reductase A/B protein YP_249127.1 1549817 D 281310 CDS YP_249128.1 68250016 3430906 1550890..1551531 1 NC_007146.2 Similar to: HI1454, YE54_HAEIN; hypothetical protein 1551531 3430906 NTHI1678 Haemophilus influenzae 86-028NP hypothetical protein YP_249128.1 1550890 D 281310 CDS YP_249129.1 68250017 3430907 1551576..1552046 1 NC_007146.2 Similar to: HI1453, YE53_HAEIN; hypothetical protein 1552046 3430907 NTHI1679 Haemophilus influenzae 86-028NP hypothetical protein YP_249129.1 1551576 D 281310 CDS YP_249130.1 68250018 3430908 complement(1552228..1552551) 1 NC_007146.2 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1552551 3430908 NTHI1680 Haemophilus influenzae 86-028NP dsDNA-mimic protein YP_249130.1 1552228 R 281310 CDS YP_249131.1 68250019 3430909 complement(1552618..1553349) 1 NC_007146.2 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 1553349 moeB 3430909 moeB Haemophilus influenzae 86-028NP molybdopterin biosynthesis protein MoeB YP_249131.1 1552618 R 281310 CDS YP_249132.1 68250020 3430910 complement(1553353..1554567) 1 NC_007146.2 Similar to: HI1448, MOEA_HAEIN; molybdopterin biosynthesis protein MoeA 1554567 moeA 3430910 moeA Haemophilus influenzae 86-028NP molybdopterin biosynthesis protein MoeA YP_249132.1 1553353 R 281310 CDS YP_249133.1 68250021 3430911 1554705..1555361 1 NC_007146.2 GTP-CH-I; involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1555361 folE 3430911 folE Haemophilus influenzae 86-028NP GTP cyclohydrolase I YP_249133.1 1554705 D 281310 CDS YP_249134.1 68250022 3430912 1555365..1555688 1 NC_007146.2 Similar to: HI1446, YCGL_HAEIN; hypothetical protein 1555688 3430912 NTHI1684 Haemophilus influenzae 86-028NP hypothetical protein YP_249134.1 1555365 D 281310 CDS YP_249135.1 68250023 3430913 1555791..1556519 1 NC_007146.2 dethiobiotin synthase 1; DTB synthetase 1; DTBS 1; DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1556519 bioD 3430913 bioD Haemophilus influenzae 86-028NP dithiobiotin synthetase YP_249135.1 1555791 D 281310 CDS YP_249136.1 68250024 3430914 complement(1556608..1557486) 1 NC_007146.2 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 1557486 metF 3430914 metF Haemophilus influenzae 86-028NP 5,10-methylenetetrahydrofolate reductase YP_249136.1 1556608 R 281310 CDS YP_249137.1 68250025 3430915 1557949..1558377 1 NC_007146.2 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1558377 rplM 3430915 rplM Haemophilus influenzae 86-028NP 50S ribosomal protein L13 YP_249137.1 1557949 D 281310 CDS YP_249138.1 68250026 3430916 1558394..1558786 1 NC_007146.2 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1558786 rpsI 3430916 rpsI Haemophilus influenzae 86-028NP 30S ribosomal protein S9 YP_249138.1 1558394 D 281310 CDS YP_249139.1 68250027 3430917 1558967..1559605 1 NC_007146.2 Similar to: HI1441, SSPA_HAEIN; stringent starvation protein A 1559605 sspA 3430917 sspA Haemophilus influenzae 86-028NP stringent starvation protein A YP_249139.1 1558967 D 281310 CDS YP_249140.1 68250028 3430918 1559605..1560057 1 NC_007146.2 Similar to: HI1440, SSPB_HAEIN; ClpXP protease specificity-enhancing factor 1560057 sspB 3430918 sspB Haemophilus influenzae 86-028NP ClpXP protease specificity-enhancing factor YP_249140.1 1559605 D 281310 CDS YP_249141.1 68250029 3430919 complement(1560093..1561970) 1 NC_007146.2 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS; catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1561970 dxs 3430919 dxs Haemophilus influenzae 86-028NP 1-deoxy-D-xylulose-5-phosphate synthase YP_249141.1 1560093 R 281310 CDS YP_249142.1 68250030 3430920 complement(1562012..1562902) 1 NC_007146.2 farnesyl-diphosphate synthase; FPP synthase; Similar to: HI1438, ISPA_HAEIN; geranyltranstransferase 1562902 ispA 3430920 ispA Haemophilus influenzae 86-028NP geranyltranstransferase YP_249142.1 1562012 R 281310 CDS YP_249143.1 68250031 3430921 complement(1562902..1563156) 1 NC_007146.2 exonuclease VII small subunit; catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1563156 xseB 3430921 xseB Haemophilus influenzae 86-028NP exodeoxyribonuclease VII small subunit YP_249143.1 1562902 R 281310 CDS YP_249144.1 68250032 3430922 1563315..1564772 1 NC_007146.2 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 1564772 thiI 3430922 thiI Haemophilus influenzae 86-028NP thiamine biosynthesis protein ThiI YP_249144.1 1563315 D 281310 CDS YP_249145.1 68250033 3430923 1564787..1565107 1 NC_007146.2 Similar to: HI1436, YQCC_HAEIN; hypothetical protein 1565107 3430923 NTHI1695 Haemophilus influenzae 86-028NP hypothetical protein YP_249145.1 1564787 D 281310 CDS YP_249146.1 68250034 3430924 1565101..1565820 1 NC_007146.2 pseudouridylate synthase; uracil hydrolyase; catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 1565820 truC 3430924 truC Haemophilus influenzae 86-028NP tRNA pseudouridine synthase C YP_249146.1 1565101 D 281310 CDS YP_249147.1 68250035 3430925 1565813..1565971 1 NC_007146.2 Similar to: HI1434.2; hypothetical protein 1565971 3430925 NTHI1697 Haemophilus influenzae 86-028NP hypothetical protein YP_249147.1 1565813 D 281310 CDS YP_249148.1 68250036 3430926 1566120..1566338 1 NC_007146.2 Similar to: HI1434.1, CSPD_HAEIN; cold shock-like protein CspD 1566338 cspD 3430926 cspD Haemophilus influenzae 86-028NP cold shock-like protein CspD YP_249148.1 1566120 D 281310 CDS YP_249149.1 68250037 3430927 complement(1566477..1566953) 1 NC_007146.2 Similar to: HI1434, YBAK_HAEIN; predicted oligonucleotide binding domain; hypothetical protein 1566953 3430927 NTHI1699 Haemophilus influenzae 86-028NP hypothetical protein YP_249149.1 1566477 R 281310 CDS YP_249150.1 68250038 3430928 1567012..1567965 1 NC_007146.2 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1567965 usg 3430928 usg Haemophilus influenzae 86-028NP aspartate-semialdehyde dehydrogenase YP_249150.1 1567012 D 281310 CDS YP_249151.1 68250039 3430929 complement(1568109..1568915) 1 NC_007146.2 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1568915 trpA 3430929 trpA Haemophilus influenzae 86-028NP tryptophan synthase subunit alpha YP_249151.1 1568109 R 281310 CDS YP_249152.1 68250040 3430930 complement(1568915..1570108) 1 NC_007146.2 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1570108 trpB 3430930 trpB Haemophilus influenzae 86-028NP tryptophan synthase subunit beta YP_249152.1 1568915 R 281310 CDS YP_249153.1 68250041 3430931 complement(1570125..1570883) 1 NC_007146.2 Similar to: HI1430, YDFG_HAEIN; oxidoreductase 1570883 3430931 NTHI1703 Haemophilus influenzae 86-028NP oxidoreductase YP_249153.1 1570125 R 281310 CDS YP_249154.1 68250042 3430932 1571063..1572097 1 NC_007146.2 AIRS; phosphoribosyl-aminoimidazole synthetase; AIR synthase; catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1572097 purM 3430932 purM Haemophilus influenzae 86-028NP phosphoribosylaminoimidazole synthetase YP_249154.1 1571063 D 281310 CDS YP_249155.1 68250043 3430933 1572152..1572790 1 NC_007146.2 GART; GAR transformylase; 5'-phosphoribosylglycinamide transformylase; glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 1572790 purN 3430933 purN Haemophilus influenzae 86-028NP phosphoribosylglycinamide formyltransferase YP_249155.1 1572152 D 281310 CDS YP_249156.1 68250044 3430934 complement(1572874..1573710) 1 NC_007146.2 Similar to: HI1427, YE27_HAEIN; ABC transporter periplasmic protein 1573710 3430934 NTHI1707 Haemophilus influenzae 86-028NP ABC transporter periplasmic protein YP_249156.1 1572874 R 281310 CDS YP_249157.2 161761263 3430935 complement(1573908..1574837) 1 NC_007146.2 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1574837 uspE 3430935 uspE Haemophilus influenzae 86-028NP universal stress protein UspE YP_249157.2 1573908 R 281310 CDS YP_249158.1 68250046 3430936 complement(1574959..1575732) 1 NC_007146.2 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1575732 fnr 3430936 fnr Haemophilus influenzae 86-028NP fumarate/nitrate reduction transcriptional regulator YP_249158.1 1574959 R 281310 CDS YP_249159.1 68250047 3430938 1576350..1576706 1 NC_007146.2 Similar to: HI1424, YE24_HAEIN; integrase/recombinase 1576706 3430938 NTHI1711 Haemophilus influenzae 86-028NP integrase/recombinase YP_249159.1 1576350 D 281310 CDS YP_249160.1 68250048 3430939 complement(1576591..1576980) 1 NC_007146.2 Similar to: HI1423, YE23_HAEIN; hypothetical protein 1576980 3430939 NTHI1712 Haemophilus influenzae 86-028NP hypothetical protein YP_249160.1 1576591 R 281310 CDS YP_249161.1 68250049 3430940 complement(1577285..1577536) 1 NC_007146.2 Similar to: HI1422, YE22_HAEIN; phage anti-repressor protein 1577536 3430940 NTHI1713 Haemophilus influenzae 86-028NP phage anti-repressor protein YP_249161.1 1577285 R 281310 CDS YP_249162.1 68250050 3430941 complement(1577874..1579145) 1 NC_007146.2 hypothetical protein 1579145 3430941 NTHI1714 Haemophilus influenzae 86-028NP hypothetical protein YP_249162.1 1577874 R 281310 CDS YP_249163.1 68250051 3430942 1579746..1579949 1 NC_007146.2 hypothetical protein 1579949 3430942 NTHI1715 Haemophilus influenzae 86-028NP hypothetical protein YP_249163.1 1579746 D 281310 CDS YP_249164.1 68250052 3430943 complement(1579927..1580085) 1 NC_007146.2 hypothetical protein 1580085 3430943 NTHI1716 Haemophilus influenzae 86-028NP hypothetical protein YP_249164.1 1579927 R 281310 CDS YP_249165.1 68250053 3430944 complement(1580413..1580634) 1 NC_007146.2 hypothetical protein 1580634 3430944 NTHI1717 Haemophilus influenzae 86-028NP hypothetical protein YP_249165.1 1580413 R 281310 CDS YP_249166.1 68250054 3430945 complement(1581561..1581896) 1 NC_007146.2 hypothetical protein 1581896 3430945 NTHI1718 Haemophilus influenzae 86-028NP hypothetical protein YP_249166.1 1581561 R 281310 CDS YP_249167.1 68250055 3430946 complement(1581899..1582978) 1 NC_007146.2 hypothetical protein 1582978 3430946 NTHI1719 Haemophilus influenzae 86-028NP hypothetical protein YP_249167.1 1581899 R 281310 CDS YP_249168.1 68250056 3430947 complement(1583030..1583728) 1 NC_007146.2 Similar to: RPC1_BPPH8; transcriptional regulator 1583728 3430947 NTHI1720 Haemophilus influenzae 86-028NP transcriptional regulator YP_249168.1 1583030 R 281310 CDS YP_249169.1 68250057 3430948 1583839..1584027 1 NC_007146.2 hypothetical protein 1584027 3430948 NTHI1721 Haemophilus influenzae 86-028NP hypothetical protein YP_249169.1 1583839 D 281310 CDS YP_249170.1 68250058 3430949 1584076..1584516 1 NC_007146.2 hypothetical protein 1584516 3430949 NTHI1722 Haemophilus influenzae 86-028NP hypothetical protein YP_249170.1 1584076 D 281310 CDS YP_249171.1 68250059 3430950 1584565..1585239 1 NC_007146.2 hypothetical protein 1585239 3430950 NTHI1723 Haemophilus influenzae 86-028NP hypothetical protein YP_249171.1 1584565 D 281310 CDS YP_249172.1 68250060 3430951 1585236..1585994 1 NC_007146.2 hypothetical protein 1585994 3430951 NTHI1724 Haemophilus influenzae 86-028NP hypothetical protein YP_249172.1 1585236 D 281310 CDS YP_249173.1 68250061 3430952 1585979..1586620 1 NC_007146.2 hypothetical protein 1586620 3430952 NTHI1725 Haemophilus influenzae 86-028NP hypothetical protein YP_249173.1 1585979 D 281310 CDS YP_249174.1 68250062 3430953 1586617..1586841 1 NC_007146.2 hypothetical protein 1586841 3430953 NTHI1726 Haemophilus influenzae 86-028NP hypothetical protein YP_249174.1 1586617 D 281310 CDS YP_249175.1 68250063 3430954 1586878..1587294 1 NC_007146.2 recombination protein NinB 1587294 ninB 3430954 ninB Haemophilus influenzae 86-028NP recombination protein NinB YP_249175.1 1586878 D 281310 CDS YP_249176.1 68250064 3430955 1587562..1587951 1 NC_007146.2 recombination protein NinG-like protein 1587951 ninG 3430955 ninG Haemophilus influenzae 86-028NP recombination protein NinG-like protein YP_249176.1 1587562 D 281310 CDS YP_249177.1 68250065 3430956 1587971..1588600 1 NC_007146.2 hypothetical protein 1588600 3430956 NTHI1729 Haemophilus influenzae 86-028NP hypothetical protein YP_249177.1 1587971 D 281310 CDS YP_249178.1 68250066 3430957 1588724..1589002 1 NC_007146.2 Similar to: HI1421, YE21_HAEIN; hypothetical protein 1589002 3430957 NTHI1730 Haemophilus influenzae 86-028NP hypothetical protein YP_249178.1 1588724 D 281310 CDS YP_249179.1 68250067 3430958 complement(1589052..1590029) 1 NC_007146.2 hypothetical protein 1590029 3430958 NTHI1731 Haemophilus influenzae 86-028NP hypothetical protein YP_249179.1 1589052 R 281310 CDS YP_249180.1 68250068 3430959 1590258..1591043 1 NC_007146.2 Similar to: HI1418, YE18_HAEIN; hypothetical protein 1591043 3430959 NTHI1733 Haemophilus influenzae 86-028NP hypothetical protein YP_249180.1 1590258 D 281310 CDS YP_249181.1 68250069 3430960 1591074..1591256 1 NC_007146.2 hypothetical protein 1591256 3430960 NTHI1734 Haemophilus influenzae 86-028NP hypothetical protein YP_249181.1 1591074 D 281310 CDS YP_249182.1 68250070 3430961 1591380..1591736 1 NC_007146.2 Similar to: HI1416, YE16_HAEIN; hypothetical protein 1591736 3430961 NTHI1735 Haemophilus influenzae 86-028NP hypothetical protein YP_249182.1 1591380 D 281310 CDS YP_249183.1 68250071 3430962 1591816..1592307 1 NC_007146.2 Similar to: HI1415, YE15_HAEIN; hypothetical protein 1592307 3430962 NTHI1736 Haemophilus influenzae 86-028NP hypothetical protein YP_249183.1 1591816 D 281310 CDS YP_249184.1 68250072 3430963 1592300..1592623 1 NC_007146.2 hypothetical protein 1592623 3430963 NTHI1737 Haemophilus influenzae 86-028NP hypothetical protein YP_249184.1 1592300 D 281310 CDS YP_249185.1 68250073 3430964 1592535..1592816 1 NC_007146.2 Similar to: HI1413, YE13_HAEIN; hypothetical protein 1592816 3430964 NTHI1738 Haemophilus influenzae 86-028NP hypothetical protein YP_249185.1 1592535 D 281310 CDS YP_249186.1 68250074 3430965 complement(1592818..1593096) 1 NC_007146.2 hypothetical protein 1593096 3430965 NTHI1739 Haemophilus influenzae 86-028NP hypothetical protein YP_249186.1 1592818 R 281310 CDS YP_249187.1 68250075 3430966 1593141..1593653 1 NC_007146.2 Similar to: HI1411, YE11_HAEIN; hypothetical protein 1593653 3430966 NTHI1740 Haemophilus influenzae 86-028NP hypothetical protein YP_249187.1 1593141 D 281310 CDS YP_249188.1 68250076 3430967 1593640..1594983 1 NC_007146.2 Similar to: HI1410, YE10_HAEIN; phage terminase large subunit 1594983 3430967 NTHI1741 Haemophilus influenzae 86-028NP phage terminase large subunit YP_249188.1 1593640 D 281310 CDS YP_249189.1 68250077 3430968 1594985..1596319 1 NC_007146.2 Similar to: HI1409, YE09_HAEIN; hypothetical protein 1596319 3430968 NTHI1742 Haemophilus influenzae 86-028NP hypothetical protein YP_249189.1 1594985 D 281310 CDS YP_249190.1 68250078 3430969 1596348..1597529 1 NC_007146.2 Similar to: HI1407, YE07_HAEIN; phage Mu protein gp30-like protein 1597529 traN 3430969 traN Haemophilus influenzae 86-028NP phage Mu protein gp30-like protein YP_249190.1 1596348 D 281310 CDS YP_249191.1 68250079 3430970 1597675..1597851 1 NC_007146.2 Similar to: HI1405; hypothetical protein 1597851 3430970 NTHI1744 Haemophilus influenzae 86-028NP hypothetical protein YP_249191.1 1597675 D 281310 CDS YP_249192.1 68250080 3430971 1598015..1599034 1 NC_007146.2 dihydroorotate oxidase; DHodehase; DHODase; DHOD; catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1599034 pyrD 3430971 pyrD Haemophilus influenzae 86-028NP dihydroorotate dehydrogenase 2 YP_249192.1 1598015 D 281310 CDS YP_249193.1 68250081 3430972 1599034..1599858 1 NC_007146.2 Similar to: HI1400, TRPH_HAEIN; TrpH 1599858 trpH 3430972 trpH Haemophilus influenzae 86-028NP TrpH YP_249193.1 1599034 D 281310 CDS YP_249194.1 68250082 3430973 complement(1599957..1600565) 1 NC_007146.2 Similar to: HI1399, YD99_HAEIN; hypothetical protein 1600565 3430973 NTHI1748 Haemophilus influenzae 86-028NP hypothetical protein YP_249194.1 1599957 R 281310 CDS YP_249195.1 68250083 3430974 complement(1600693..1602087) 1 NC_007146.2 fumarase; class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1602087 fumC 3430974 fumC Haemophilus influenzae 86-028NP fumarate hydratase YP_249195.1 1600693 R 281310 CDS YP_249196.1 68250084 3430975 complement(1602237..1603175) 1 NC_007146.2 glycosyl transferase family protein 1603175 3430975 NTHI1750 Haemophilus influenzae 86-028NP glycosyl transferase family protein YP_249196.1 1602237 R 281310 CDS YP_249197.1 68250085 3430977 1603831..1604265 1 NC_007146.2 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 1604265 holC 3430977 holC Haemophilus influenzae 86-028NP DNA polymerase III subunit chi YP_249197.1 1603831 D 281310 CDS YP_249198.1 68250086 3430978 1604350..1604520 1 NC_007146.2 Similar to: HI1396, YD96_HAEIN; hypothetical protein 1604520 3430978 NTHI1754 Haemophilus influenzae 86-028NP hypothetical protein YP_249198.1 1604350 D 281310 CDS YP_249199.1 68250087 3430979 1604533..1604907 1 NC_007146.2 Similar to: HI1395, YD95_HAEIN; hypothetical protein 1604907 3430979 NTHI1755 Haemophilus influenzae 86-028NP hypothetical protein YP_249199.1 1604533 D 281310 CDS YP_249200.1 68250088 3430980 1604935..1605102 1 NC_007146.2 hypothetical protein 1605102 3430980 NTHI1756 Haemophilus influenzae 86-028NP hypothetical protein YP_249200.1 1604935 D 281310 CDS YP_249201.1 68250089 3430981 1605129..1605443 1 NC_007146.2 Similar to: HI1394, YD94_HAEIN; hypothetical protein 1605443 3430981 NTHI1757 Haemophilus influenzae 86-028NP hypothetical protein YP_249201.1 1605129 D 281310 CDS YP_249202.1 68250090 3430982 1605487..1605888 1 NC_007146.2 hypothetical protein 1605888 3430982 NTHI1758 Haemophilus influenzae 86-028NP hypothetical protein YP_249202.1 1605487 D 281310 CDS YP_249203.1 68250091 3430983 1605940..1608804 1 NC_007146.2 valine--tRNA ligase; ValRS; valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1608804 valS 3430983 valS Haemophilus influenzae 86-028NP valyl-tRNA synthetase YP_249203.1 1605940 D 281310 CDS YP_249204.1 68250092 3430984 complement(1608839..1608946) 1 NC_007146.2 hypothetical protein 1608946 3430984 NTHI1762 Haemophilus influenzae 86-028NP hypothetical protein YP_249204.1 1608839 R 281310 CDS YP_249205.1 68250093 3430985 complement(1609234..1610667) 1 NC_007146.2 IGPS; PRAI; monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1610667 trpC 3430985 trpC Haemophilus influenzae 86-028NP bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_249205.1 1609234 R 281310 CDS YP_249206.1 68250094 3430986 complement(1610705..1611706) 1 NC_007146.2 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1611706 trpD 3430986 trpD Haemophilus influenzae 86-028NP anthranilate phosphoribosyltransferase YP_249206.1 1610705 R 281310 CDS YP_249207.1 68250095 3430987 complement(1611759..1612145) 1 NC_007146.2 Similar to: HI1388.1, YD8A_HAEIN; hypothetical protein 1612145 3430987 NTHI1765 Haemophilus influenzae 86-028NP hypothetical protein YP_249207.1 1611759 R 281310 CDS YP_249208.1 68250096 3430988 complement(1612194..1612781) 1 NC_007146.2 glutamine amido-transferase; TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1612781 trpG 3430988 trpG Haemophilus influenzae 86-028NP anthranilate synthase component II YP_249208.1 1612194 R 281310 CDS YP_249209.1 68250097 3430989 complement(1612794..1614350) 1 NC_007146.2 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1614350 trpE 3430989 trpE Haemophilus influenzae 86-028NP anthranilate synthase component I YP_249209.1 1612794 R 281310 CDS YP_249210.1 68250098 3430991 complement(1615485..1615982) 1 NC_007146.2 Similar to: HI1385, FTN2_HAEIN; ferritin 1615982 ftnB 3430991 ftnB Haemophilus influenzae 86-028NP ferritin YP_249210.1 1615485 R 281310 CDS YP_249211.1 68250099 3430992 complement(1615998..1616546) 1 NC_007146.2 Similar to: HI1384, FTN1_HAEIN; ferritin 1616546 ftnA 3430992 ftnA Haemophilus influenzae 86-028NP ferritin YP_249211.1 1615998 R 281310 CDS YP_249212.1 68250100 3430993 1616989..1618008 1 NC_007146.2 PBP; Similar to: HI1383, PSTS_HAEIN; phosphate-binding periplasmic protein PstS 1618008 pstS 3430993 pstS Haemophilus influenzae 86-028NP phosphate-binding periplasmic protein PstS YP_249212.1 1616989 D 281310 CDS YP_249213.1 68250101 3430994 1618100..1619047 1 NC_007146.2 Similar to: HI1382, PSTC_HAEIN; phosphate transport system permease protein PstC 1619047 pstC 3430994 pstC Haemophilus influenzae 86-028NP phosphate transport system permease protein PstC YP_249213.1 1618100 D 281310 CDS YP_249214.1 68250102 3430995 1619049..1619897 1 NC_007146.2 Similar to: HI1381, PSTA_HAEIN; phosphate transport system permease protein PstA 1619897 pstA 3430995 pstA Haemophilus influenzae 86-028NP phosphate transport system permease protein PstA YP_249214.1 1619049 D 281310 CDS YP_249215.1 68250103 3430996 1619907..1620674 1 NC_007146.2 phosphate-transporting ATPase; ABC phosphate transporter; ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1620674 pstB 3430996 pstB Haemophilus influenzae 86-028NP phosphate transporter ATP-binding protein YP_249215.1 1619907 D 281310 CDS YP_249216.1 68250104 3430997 1620771..1621466 1 NC_007146.2 Similar to: HI1379, PHOB_HAEIN; phosphate regulon transcriptional regulatory protein PhoB 1621466 phoB 3430997 phoB Haemophilus influenzae 86-028NP phosphate regulon transcriptional regulatory protein PhoB YP_249216.1 1620771 D 281310 CDS YP_249217.1 68250105 3430998 1621463..1622740 1 NC_007146.2 Similar to: HI1378, PHOR_HAEIN; phosphate regulon sensor protein PhoR 1622740 phoR 3430998 phoR Haemophilus influenzae 86-028NP phosphate regulon sensor protein PhoR YP_249217.1 1621463 D 281310 CDS YP_249218.1 68250106 3430999 complement(1623432..1624853) 1 NC_007146.2 exonuclease I; DNA deoxyribophosphodiesterase; dRPase; Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 1624853 sbcB 3430999 sbcB Haemophilus influenzae 86-028NP exonuclease I YP_249218.1 1623432 R 281310 CDS YP_249219.1 68250107 3431000 complement(1624866..1625741) 1 NC_007146.2 Similar to: HI1376, YD76_HAEIN; hypothetical protein 1625741 3431000 NTHI1781 Haemophilus influenzae 86-028NP hypothetical protein YP_249219.1 1624866 R 281310 CDS YP_249220.1 68250108 3431001 complement(1625745..1626653) 1 NC_007146.2 Similar to: HI1375, YD75_HAEIN; hypothetical protein 1626653 3431001 NTHI1782 Haemophilus influenzae 86-028NP hypothetical protein YP_249220.1 1625745 R 281310 CDS YP_249221.1 68250109 3431002 complement(1626723..1631255) 1 NC_007146.2 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1631255 mukB 3431002 mukB Haemophilus influenzae 86-028NP cell division protein MukB YP_249221.1 1626723 R 281310 CDS YP_249222.1 68250110 3431003 complement(1631255..1631989) 1 NC_007146.2 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1631989 3431003 NTHI1785 Haemophilus influenzae 86-028NP condesin subunit E YP_249222.1 1631255 R 281310 CDS YP_249223.1 68250111 3431004 complement(1631993..1633051) 1 NC_007146.2 endonuclease HaeII; R.HaeII; Similar to: T2H2_HAEAE; type II restriction enzyme HaeII 1633051 haeIIR 3431004 haeIIR Haemophilus influenzae 86-028NP type II restriction enzyme HaeII YP_249223.1 1631993 R 281310 CDS YP_249224.1 68250112 3431005 complement(1633054..1634010) 1 NC_007146.2 cytosine-specific methyltransferase HaeII; M.HaeII; Similar to: MTH2_HAEAE; modification methylase HaeII 1634010 haeIIM 3431005 haeIIM Haemophilus influenzae 86-028NP modification methylase HaeII YP_249224.1 1633054 R 281310 CDS YP_249225.1 68250113 3431006 complement(1634023..1635450) 1 NC_007146.2 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1635450 mukF 3431006 mukF Haemophilus influenzae 86-028NP condesin subunit F YP_249225.1 1634023 R 281310 CDS YP_249226.1 68250114 3431007 1635507..1636439 1 NC_007146.2 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1636439 3431007 NTHI1789 Haemophilus influenzae 86-028NP C32 tRNA thiolase YP_249226.1 1635507 D 281310 CDS YP_249227.1 68250115 3431008 1636441..1636770 1 NC_007146.2 Similar to: HI1371, YCCK_HAEIN; dissimilatory sulfite reductase, desulfoviridin subunit gamma 1636770 3431008 NTHI1790 Haemophilus influenzae 86-028NP dissimilatory sulfite reductase, desulfoviridin subunit gamma YP_249227.1 1636441 D 281310 CDS YP_249228.1 68250116 3431009 1636878..1637087 1 NC_007146.2 Similar to: HI1370, MOP_HAEIN; molybdenum-pterin binding protein 1637087 mop 3431009 mop Haemophilus influenzae 86-028NP molybdenum-pterin binding protein YP_249228.1 1636878 D 281310 CDS YP_249229.1 68250117 3431011 1639787..1642567 1 NC_007146.2 Similar to: HI1368, PQQL_HAEIN; zinc protease 1642567 pqqL 3431011 pqqL Haemophilus influenzae 86-028NP zinc protease YP_249229.1 1639787 D 281310 CDS YP_249230.1 68250118 3431012 complement(1642690..1644621) 1 NC_007146.2 threonine--tRNA ligase; ThrRS; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1644621 thrS 3431012 thrS Haemophilus influenzae 86-028NP threonyl-tRNA synthetase YP_249230.1 1642690 R 281310 CDS YP_249231.1 68250119 3431013 1644905..1645489 1 NC_007146.2 ACP phosphodiesterase; Similar to: HI1366, ACPD_HAEIN; ACP phosphodieterase 1645489 acpD 3431013 acpD Haemophilus influenzae 86-028NP ACP phosphodieterase YP_249231.1 1644905 D 281310 CDS YP_249232.1 68250120 3431014 complement(1645566..1648172) 1 NC_007146.2 Omega-protein; relaxing enzyme; untwisting enzyme; swivelase; catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1648172 topA 3431014 topA Haemophilus influenzae 86-028NP DNA topoisomerase I YP_249232.1 1645566 R 281310 CDS YP_249233.1 68250121 3431015 1648268..1649185 1 NC_007146.2 Similar to: HI1364, YHCS_HAEIN; HTH-type transcriptional regulator 1649185 3431015 NTHI1800 Haemophilus influenzae 86-028NP HTH-type transcriptional regulator YP_249233.1 1648268 D 281310 CDS YP_249234.1 68250122 3431016 complement(1649249..1650673) 1 NC_007146.2 pyridine nucleotide transhydrogenase subunit beta; nicotinamide nucleotide transhydrogenase subunit beta; catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 1650673 pntB 3431016 pntB Haemophilus influenzae 86-028NP pyridine nucleotide transhydrogenase YP_249234.1 1649249 R 281310 CDS YP_249235.1 68250123 3431017 complement(1650684..1652222) 1 NC_007146.2 pyridine nucleotide transhydrogenase subunit alpha; nicotinamide nucleotide transhydrogenase subunit alpha; forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 1652222 pntA 3431017 pntA Haemophilus influenzae 86-028NP NAD(P) transhydrogenase subunit alpha YP_249235.1 1650684 R 281310 CDS YP_249236.1 68250124 3431018 complement(1652483..1654948) 1 NC_007146.2 Similar to: HI1361, PHSG_HAEIN; glycogen phosphorylase 1654948 glgP 3431018 glgP Haemophilus influenzae 86-028NP glycogen phosphorylase YP_249236.1 1652483 R 281310 CDS YP_249237.1 68250125 3431019 complement(1655195..1656625) 1 NC_007146.2 Starch [bacterial glycogen] synthase; catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 1656625 glgA 3431019 glgA Haemophilus influenzae 86-028NP glycogen synthase YP_249237.1 1655195 R 281310 CDS YP_249238.1 68250126 3431020 complement(1656733..1658067) 1 NC_007146.2 ADP-glucose synthase; ADP-glucose pyrophosphorylase; ADPGlc PPase; catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1658067 glgC 3431020 glgC Haemophilus influenzae 86-028NP glucose-1-phosphate adenylyltransferase YP_249238.1 1656733 R 281310 CDS YP_249239.1 68250127 3431021 complement(1658057..1660033) 1 NC_007146.2 Similar to: HI1358, GLGX_HAEIN; glycogen operon protein GlgX 1660033 glgX 3431021 glgX Haemophilus influenzae 86-028NP glycogen operon protein GlgX YP_249239.1 1658057 R 281310 CDS YP_249240.1 68250128 3431022 complement(1660132..1662324) 1 NC_007146.2 glycogen branching enzyme; BE; 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase; catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 1662324 glgB 3431022 glgB Haemophilus influenzae 86-028NP glycogen branching enzyme YP_249240.1 1660132 R 281310 CDS YP_249241.1 68250129 3431023 complement(1662334..1664433) 1 NC_007146.2 amylomaltase; disproportionating enzyme; D-enzyme; Similar to: HI1356, MALQ_HAEIN; 4-alpha-glucanotransferase 1664433 malQ 3431023 malQ Haemophilus influenzae 86-028NP 4-alpha-glucanotransferase YP_249241.1 1662334 R 281310 CDS YP_249242.1 68250130 3431024 complement(1664495..1664959) 1 NC_007146.2 Similar to: HI1355, YD55_HAEIN; hypothetical protein 1664959 3431024 NTHI1811 Haemophilus influenzae 86-028NP hypothetical protein YP_249242.1 1664495 R 281310 CDS YP_249243.1 68250131 3431025 complement(1665025..1666698) 1 NC_007146.2 glutamine--tRNA ligase; GlnRS; catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 1666698 glnS 3431025 glnS Haemophilus influenzae 86-028NP glutaminyl-tRNA synthetase YP_249243.1 1665025 R 281310 CDS YP_249244.1 68250132 3431026 complement(1667118..1668593) 1 NC_007146.2 RNase G; cytoplasmic axial filament protein; involved in the processing of the 5'end of 16S rRNA; ribonuclease G 1668593 cafA 3431026 cafA Haemophilus influenzae 86-028NP ribonuclease G YP_249244.1 1667118 R 281310 CDS YP_249245.1 68250133 3431027 1668709..1670223 1 NC_007146.2 proline permease; Similar to: HI1352, PUTP_HAEIN; sodium/proline symporter 1670223 putP 3431027 putP Haemophilus influenzae 86-028NP sodium/proline symporter YP_249245.1 1668709 D 281310 CDS YP_249246.1 68250134 3431028 1670220..1671185 1 NC_007146.2 Similar to: HI1351, YECP_HAEIN; hypothetical protein 1671185 3431028 NTHI1815 Haemophilus influenzae 86-028NP hypothetical protein YP_249246.1 1670220 D 281310 CDS YP_249247.1 68250135 3431029 complement(1671228..1672106) 1 NC_007146.2 cytidine aminohydrolase; CDA; Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 1672106 cdd 3431029 cdd Haemophilus influenzae 86-028NP cytidine deaminase YP_249247.1 1671228 R 281310 CDS YP_249248.1 68250136 3431030 1672380..1672862 1 NC_007146.2 Similar to: HI1349, YD49_HAEIN; DNA-binding ferritin-like protein 1672862 3431030 NTHI1817 Haemophilus influenzae 86-028NP DNA-binding ferritin-like protein YP_249248.1 1672380 D 281310 CDS YP_249249.1 68250137 3431031 complement(1673434..1674672) 1 NC_007146.2 tripeptide aminopeptidase; aminotripeptidase; tripeptidase; catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1674672 pepT 3431031 pepT Haemophilus influenzae 86-028NP peptidase T YP_249249.1 1673434 R 281310 CDS YP_249250.1 68250138 3431032 1674942..1676087 1 NC_007146.2 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase protein 1676087 potA 3431032 potA Haemophilus influenzae 86-028NP putrescine/spermidine ABC transporter ATPase protein YP_249250.1 1674942 D 281310 CDS YP_249251.1 68250139 3431033 1676071..1676931 1 NC_007146.2 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1676931 potB 3431033 potB Haemophilus influenzae 86-028NP spermidine/putrescine ABC transporter membrane protein YP_249251.1 1676071 D 281310 CDS YP_249252.1 68250140 3431034 1676931..1677701 1 NC_007146.2 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1677701 potC 3431034 potC Haemophilus influenzae 86-028NP spermidine/putrescine ABC transporter membrane protein YP_249252.1 1676931 D 281310 CDS YP_249253.1 68250141 3431035 1677748..1678914 1 NC_007146.2 SPBP; Similar to: HI1344, POT1_HAEIN; spermidine/putrescine-binding periplasmic protein 1 1678914 potD1 3431035 potD1 Haemophilus influenzae 86-028NP spermidine/putrescine-binding periplasmic protein 1 YP_249253.1 1677748 D 281310 CDS YP_249254.1 68250142 3431036 complement(1678995..1680938) 1 NC_007146.2 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1680938 uupA 3431036 uupA Haemophilus influenzae 86-028NP ABC transporter ATPase YP_249254.1 1678995 R 281310 CDS YP_249255.1 68250143 3431037 complement(1681032..1682417) 1 NC_007146.2 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 1682417 3431037 NTHI1825 Haemophilus influenzae 86-028NP deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_249255.1 1681032 R 281310 CDS YP_249256.1 68250144 3431038 complement(1682510..1683205) 1 NC_007146.2 Similar to: HI1298, YOHK_HAEIN; effector of murein hydrolase 1683205 3431038 NTHI1826 Haemophilus influenzae 86-028NP effector of murein hydrolase YP_249256.1 1682510 R 281310 CDS YP_249257.1 68250145 3431039 complement(1683224..1683646) 1 NC_007146.2 Similar to: HI1297, YOHJ_HAEIN; hypothetical protein 1683646 3431039 NTHI1827 Haemophilus influenzae 86-028NP hypothetical protein YP_249257.1 1683224 R 281310 CDS YP_249258.1 68250146 3431040 1683761..1684243 1 NC_007146.2 Similar to: HI1296, YC96_HAEIN; micrococcal nuclease-like protein 1684243 3431040 NTHI1828 Haemophilus influenzae 86-028NP micrococcal nuclease-like protein YP_249258.1 1683761 D 281310 CDS YP_249259.1 68250147 3431041 1684245..1685444 1 NC_007146.2 Similar to: HI1295, CSD_HAEIN; selenocysteine lyase 1685444 nifS 3431041 nifS Haemophilus influenzae 86-028NP selenocysteine lyase YP_249259.1 1684245 D 281310 CDS YP_249260.1 68250148 3431042 1685441..1685821 1 NC_007146.2 Similar to: HI1293, YC93_HAEIN; hypothetical protein 1685821 3431042 NTHI1830 Haemophilus influenzae 86-028NP hypothetical protein YP_249260.1 1685441 D 281310 CDS YP_249261.1 68250149 3431043 1685812..1686609 1 NC_007146.2 Similar to: HI1292, YC92_HAEIN; hypothetical protein 1686609 3431043 NTHI1831 Haemophilus influenzae 86-028NP hypothetical protein YP_249261.1 1685812 D 281310 CDS YP_249262.1 68250150 3431044 1686653..1687492 1 NC_007146.2 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1687492 queF 3431044 queF Haemophilus influenzae 86-028NP 7-cyano-7-deazaguanine reductase YP_249262.1 1686653 D 281310 CDS YP_249263.1 68250151 3431045 complement(1687525..1688649) 1 NC_007146.2 CM; PDH; catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 1688649 tyrA 3431045 tyrA Haemophilus influenzae 86-028NP bifunctional chorismate mutase/prephenate dehydrogenase YP_249263.1 1687525 R 281310 CDS YP_249264.1 68250152 3431046 complement(1688739..1689659) 1 NC_007146.2 tRNA pseudouridine 55 synthase; Psi55 synthase; pseudouridylate synthase; Uracil hydrolyase; catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1689659 truB 3431046 truB Haemophilus influenzae 86-028NP tRNA pseudouridine synthase B YP_249264.1 1688739 R 281310 CDS YP_249265.1 68250153 3431047 complement(1689659..1690045) 1 NC_007146.2 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1690045 rbfA 3431047 rbfA Haemophilus influenzae 86-028NP ribosome-binding factor A YP_249265.1 1689659 R 281310 CDS YP_249266.1 68250154 3431048 1690210..1691880 1 NC_007146.2 M.HindVIIP; Similar to: HI1287, T1MH_HAEIN; type I restriction enzyme HindVIIP M protein 1691880 hsdM3 3431048 hsdM3 Haemophilus influenzae 86-028NP type I restriction enzyme HindVIIP M protein YP_249266.1 1690210 D 281310 CDS YP_249267.1 68250155 3431049 1691873..1693138 1 NC_007146.2 S protein; S.HindVIIP; Similar to: HI1286, T1SH_HAEIN; type I restriction enzyme HindVIIP specificity protein 1693138 hsdS3 3431049 hsdS3 Haemophilus influenzae 86-028NP type I restriction enzyme HindVIIP specificity protein YP_249267.1 1691873 D 281310 CDS YP_249268.1 68250156 3431050 1693131..1694177 1 NC_007146.2 hypothetical protein 1694177 3431050 NTHI1841 Haemophilus influenzae 86-028NP hypothetical protein YP_249268.1 1693131 D 281310 CDS YP_249269.1 68250157 3431107 1694179..1697346 1 NC_007146.2 Similar to: HI1285, T1RH_HAEIN; type I restriction enzyme HindVIIP R protein 1697346 hsdR3 3431107 hsdR3 Haemophilus influenzae 86-028NP type I restriction enzyme HindVIIP R protein YP_249269.1 1694179 D 281310 CDS YP_249270.1 68250158 3431108 complement(1697425..1699959) 1 NC_007146.2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1699959 infB 3431108 infB Haemophilus influenzae 86-028NP translation initiation factor IF-2 YP_249270.1 1697425 R 281310 CDS YP_249271.1 68250159 3431109 complement(1699971..1701458) 1 NC_007146.2 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1701458 nusA 3431109 nusA Haemophilus influenzae 86-028NP transcription elongation factor NusA YP_249271.1 1699971 R 281310 CDS YP_249272.1 68250160 3431110 complement(1701475..1701930) 1 NC_007146.2 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1701930 3431110 NTHI1846 Haemophilus influenzae 86-028NP hypothetical protein YP_249272.1 1701475 R 281310 CDS YP_249273.1 68250161 3431112 complement(1703591..1704355) 1 NC_007146.2 hypothetical protein 1704355 3431112 NTHI1849 Haemophilus influenzae 86-028NP hypothetical protein YP_249273.1 1703591 R 281310 CDS YP_249274.1 68250162 3431113 complement(1704359..1704886) 1 NC_007146.2 hypothetical protein 1704886 3431113 NTHI1850 Haemophilus influenzae 86-028NP hypothetical protein YP_249274.1 1704359 R 281310 CDS YP_249275.1 68250163 3431114 complement(1704896..1706035) 1 NC_007146.2 hypothetical protein 1706035 3431114 NTHI1851 Haemophilus influenzae 86-028NP hypothetical protein YP_249275.1 1704896 R 281310 CDS YP_249276.1 68250164 3431115 complement(1706052..1706420) 1 NC_007146.2 hypothetical protein 1706420 3431115 NTHI1852 Haemophilus influenzae 86-028NP hypothetical protein YP_249276.1 1706052 R 281310 CDS YP_249277.1 68250165 3431116 complement(1706434..1707255) 1 NC_007146.2 hypothetical protein 1707255 3431116 NTHI1853 Haemophilus influenzae 86-028NP hypothetical protein YP_249277.1 1706434 R 281310 CDS YP_249278.1 68250166 3431117 complement(1707312..1707815) 1 NC_007146.2 hypothetical protein 1707815 3431117 NTHI1855 Haemophilus influenzae 86-028NP hypothetical protein YP_249278.1 1707312 R 281310 CDS YP_249279.1 68250167 3431118 complement(1707812..1708414) 1 NC_007146.2 Similar to: YO32_BPHP1; hypothetical protein 1708414 3431118 NTHI1856 Haemophilus influenzae 86-028NP hypothetical protein YP_249279.1 1707812 R 281310 CDS YP_249280.1 68250168 3431119 complement(1708426..1710948) 1 NC_007146.2 Similar to: HI1403, VPH_BPHP1; tail fiber protein 1710948 3431119 NTHI1857 Haemophilus influenzae 86-028NP tail fiber protein YP_249280.1 1708426 R 281310 CDS YP_249281.1 68250169 3431120 complement(1710957..1711493) 1 NC_007146.2 Similar to: VPI_BPP2; bacteriophage P2-related tail formation protein gpI 1711493 3431120 NTHI1858 Haemophilus influenzae 86-028NP bacteriophage P2-related tail formation protein gpI YP_249281.1 1710957 R 281310 CDS YP_249282.1 68250170 3431121 complement(1711483..1712397) 1 NC_007146.2 Similar to: VPJ_BPP2; phage-like baseplate assembly protein 1712397 3431121 NTHI1860 Haemophilus influenzae 86-028NP phage-like baseplate assembly protein YP_249282.1 1711483 R 281310 CDS YP_249283.1 68250171 3431122 complement(1712394..1712732) 1 NC_007146.2 baseplate assembly protein W 1712732 3431122 NTHI1861 Haemophilus influenzae 86-028NP baseplate assembly protein W YP_249283.1 1712394 R 281310 CDS YP_249284.1 68250172 3431123 complement(1712734..1713333) 1 NC_007146.2 phage P2-like baseplate assembly protein 1713333 3431123 NTHI1862 Haemophilus influenzae 86-028NP phage P2-like baseplate assembly protein YP_249284.1 1712734 R 281310 CDS YP_249285.1 68250173 3431124 complement(1713437..1713865) 1 NC_007146.2 hypothetical protein 1713865 3431124 NTHI1863 Haemophilus influenzae 86-028NP hypothetical protein YP_249285.1 1713437 R 281310 CDS YP_249286.1 68250174 3431125 complement(1713874..1714431) 1 NC_007146.2 hypothetical protein 1714431 3431125 NTHI1864 Haemophilus influenzae 86-028NP hypothetical protein YP_249286.1 1713874 R 281310 CDS YP_249287.1 68250175 3431126 complement(1714529..1714981) 1 NC_007146.2 hypothetical protein 1714981 3431126 NTHI1865 Haemophilus influenzae 86-028NP hypothetical protein YP_249287.1 1714529 R 281310 CDS YP_249288.1 68250176 3431127 complement(1714959..1715159) 1 NC_007146.2 hypothetical protein 1715159 3431127 NTHI1866 Haemophilus influenzae 86-028NP hypothetical protein YP_249288.1 1714959 R 281310 CDS YP_249289.1 68250177 3431128 complement(1715203..1717167) 1 NC_007146.2 phage-like tail protein 1717167 3431128 NTHI1867 Haemophilus influenzae 86-028NP phage-like tail protein YP_249289.1 1715203 R 281310 CDS YP_249290.1 68250178 3431129 complement(1717210..1717977) 1 NC_007146.2 hypothetical protein 1717977 3431129 NTHI1869 Haemophilus influenzae 86-028NP hypothetical protein YP_249290.1 1717210 R 281310 CDS YP_249291.1 68250179 3431130 1718022..1718360 1 NC_007146.2 hypothetical protein 1718360 3431130 NTHI1870 Haemophilus influenzae 86-028NP hypothetical protein YP_249291.1 1718022 D 281310 CDS YP_249292.1 68250180 3431131 complement(1718371..1718553) 1 NC_007146.2 hypothetical protein 1718553 3431131 NTHI1871 Haemophilus influenzae 86-028NP hypothetical protein YP_249292.1 1718371 R 281310 CDS YP_249293.1 68250181 3431132 1718657..1719004 1 NC_007146.2 hypothetical protein 1719004 3431132 NTHI1872 Haemophilus influenzae 86-028NP hypothetical protein YP_249293.1 1718657 D 281310 CDS YP_249294.1 68250182 3431133 complement(1719005..1719466) 1 NC_007146.2 bacteriophage tail completion protein gpS-like protein 1719466 3431133 NTHI1873 Haemophilus influenzae 86-028NP bacteriophage tail completion protein gpS-like protein YP_249294.1 1719005 R 281310 CDS YP_249295.1 68250183 3431134 complement(1719466..1719852) 1 NC_007146.2 bacteriophage tail completion protein gpR-like protein 1719852 3431134 NTHI1874 Haemophilus influenzae 86-028NP bacteriophage tail completion protein gpR-like protein YP_249295.1 1719466 R 281310 CDS YP_249296.1 68250184 3431135 complement(1719902..1720009) 1 NC_007146.2 hypothetical protein 1720009 3431135 NTHI1875 Haemophilus influenzae 86-028NP hypothetical protein YP_249296.1 1719902 R 281310 CDS YP_249297.1 68250185 3431136 complement(1720042..1720164) 1 NC_007146.2 hypothetical protein 1720164 3431136 NTHI1876 Haemophilus influenzae 86-028NP hypothetical protein YP_249297.1 1720042 R 281310 CDS YP_249298.1 68250186 3431137 complement(1720161..1720376) 1 NC_007146.2 DnaK suppressor protein 1720376 3431137 NTHI1878 Haemophilus influenzae 86-028NP DnaK suppressor protein YP_249298.1 1720161 R 281310 CDS YP_249299.1 68250187 3431138 complement(1720551..1720901) 1 NC_007146.2 hypothetical protein 1720901 3431138 NTHI1879 Haemophilus influenzae 86-028NP hypothetical protein YP_249299.1 1720551 R 281310 CDS YP_249300.1 68250188 3431139 complement(1720886..1721404) 1 NC_007146.2 Lysis protein; muramidase; endolysin; Similar to: LYCV_BPP1; phage-like lysozyme 1721404 3431139 NTHI1880 Haemophilus influenzae 86-028NP phage-like lysozyme YP_249300.1 1720886 R 281310 CDS YP_249301.1 68250189 3431140 complement(1721397..1721618) 1 NC_007146.2 hypothetical protein 1721618 3431140 NTHI1881 Haemophilus influenzae 86-028NP hypothetical protein YP_249301.1 1721397 R 281310 CDS YP_249302.1 68250190 3431141 complement(1721620..1721829) 1 NC_007146.2 hypothetical protein 1721829 3431141 NTHI1882 Haemophilus influenzae 86-028NP hypothetical protein YP_249302.1 1721620 R 281310 CDS YP_249303.1 68250191 3431142 complement(1721829..1722335) 1 NC_007146.2 hypothetical protein 1722335 3431142 NTHI1883 Haemophilus influenzae 86-028NP hypothetical protein YP_249303.1 1721829 R 281310 CDS YP_249304.1 68250192 3431143 complement(1722629..1723279) 1 NC_007146.2 Similar to: VPM_BPP2; terminase, endonuclease subunit 1723279 3431143 NTHI1884 Haemophilus influenzae 86-028NP terminase, endonuclease subunit YP_249304.1 1722629 R 281310 CDS YP_249305.1 68250193 3431144 complement(1723291..1724340) 1 NC_007146.2 Similar to: VPN_BPP2; major capsid protein 1724340 3431144 NTHI1885 Haemophilus influenzae 86-028NP major capsid protein YP_249305.1 1723291 R 281310 CDS YP_249306.1 68250194 3431145 complement(1724361..1725176) 1 NC_007146.2 Similar to: VPO_BPP2; capsid scaffolding protein 1725176 3431145 NTHI1887 Haemophilus influenzae 86-028NP capsid scaffolding protein YP_249306.1 1724361 R 281310 CDS YP_249307.1 68250195 3431146 1725341..1727122 1 NC_007146.2 Similar to: VPP_BPP2; terminase, ATPase subunit 1727122 3431146 NTHI1888 Haemophilus influenzae 86-028NP terminase, ATPase subunit YP_249307.1 1725341 D 281310 CDS YP_249308.1 68250196 3431147 1727132..1728142 1 NC_007146.2 Similar to: VPQ_BPP2; portal vertex protein 1728142 3431147 NTHI1890 Haemophilus influenzae 86-028NP portal vertex protein YP_249308.1 1727132 D 281310 CDS YP_249309.1 68250197 3431148 complement(1728850..1729524) 1 NC_007146.2 CMP-N-acetylneuraminic acid synthetase; CMP-NeuNAc synthetase; CMP-sialic acid synthetase; Similar to: HI1279, NEUA_HAEIN; acylneuraminate cytidylyltransferase 1729524 siaB 3431148 siaB Haemophilus influenzae 86-028NP acylneuraminate cytidylyltransferase YP_249309.1 1728850 R 281310 CDS YP_249310.1 68250198 3431149 1729638..1730300 1 NC_007146.2 Similar to: HI1278, YC78_HAEIN; NAD(P)H nitroreductase 1730300 3431149 NTHI1892 Haemophilus influenzae 86-028NP NAD(P)H nitroreductase YP_249310.1 1729638 D 281310 CDS YP_249311.2 161761262 3431150 complement(1730347..1731459) 1 NC_007146.2 Similar to: HI1277, MRP_HAEIN; ATPase 1731459 mrp 3431150 mrp Haemophilus influenzae 86-028NP ATPase YP_249311.2 1730347 R 281310 CDS YP_249312.1 68250200 3431151 1731610..1733658 1 NC_007146.2 methionine--tRNA ligase; MetRS; methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1733658 metG 3431151 metG Haemophilus influenzae 86-028NP methionyl-tRNA synthetase YP_249312.1 1731610 D 281310 CDS YP_249313.1 68250201 3431152 1733769..1734629 1 NC_007146.2 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1734629 tehB 3431152 tehB Haemophilus influenzae 86-028NP tellurite resistance protein TehB YP_249313.1 1733769 D 281310 CDS YP_249314.1 68250202 3431153 complement(1734673..1735374) 1 NC_007146.2 glyoxalase II; Glx II; Similar to: HI1274, GLO2_HAEIN; hydroxyacylglutathione hydrolase 1735374 gloB 3431153 gloB Haemophilus influenzae 86-028NP hydroxyacylglutathione hydrolase YP_249314.1 1734673 R 281310 CDS YP_249315.1 68250203 3431154 complement(1735426..1736232) 1 NC_007146.2 Similar to: HI1273, YC73_HAEIN; hypothetical protein 1736232 3431154 NTHI1897 Haemophilus influenzae 86-028NP hypothetical protein YP_249315.1 1735426 R 281310 CDS YP_249316.1 68250204 3431155 1736468..1736944 1 NC_007146.2 Similar to: HI1266, YC66_HAEIN; hypothetical protein 1736944 3431155 NTHI1898 Haemophilus influenzae 86-028NP hypothetical protein YP_249316.1 1736468 D 281310 CDS YP_249317.1 68250205 3431156 1737081..1738844 1 NC_007146.2 Similar to: HI1265, YCAO_HAEIN; hypothetical protein 1738844 3431156 NTHI1899 Haemophilus influenzae 86-028NP hypothetical protein YP_249317.1 1737081 D 281310 CDS YP_249318.1 68250206 3431157 1739444..1742086 1 NC_007146.2 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1742086 gyrA 3431157 gyrA Haemophilus influenzae 86-028NP DNA gyrase subunit A YP_249318.1 1739444 D 281310 CDS YP_249319.1 68250207 3431158 complement(1742141..1743217) 1 NC_007146.2 homoserine O-trans-acetylase; homoserine transacetylase; HTA; Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase 1743217 metX 3431158 metX Haemophilus influenzae 86-028NP homoserine O-acetyltransferase YP_249319.1 1742141 R 281310 CDS YP_249320.1 68250208 3431159 1743321..1744055 1 NC_007146.2 Similar to: HI1262, SANA_HAEIN; SanA 1744055 sanA 3431159 sanA Haemophilus influenzae 86-028NP SanA YP_249320.1 1743321 D 281310 CDS YP_249321.1 68250209 3431160 complement(1744343..1745656) 1 NC_007146.2 folylpoly-gamma-glutamate synthetase; FPGS; Similar to: HI1261, FOLC_HAEIN; folylpolyglutamate synthase 1745656 folC 3431160 folC Haemophilus influenzae 86-028NP folylpolyglutamate synthase YP_249321.1 1744343 R 281310 CDS YP_249322.1 68250210 3431161 complement(1745649..1746539) 1 NC_007146.2 ACCASE beta chain; catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 1746539 accD 3431161 accD Haemophilus influenzae 86-028NP acetyl-CoA carboxylase subunit beta YP_249322.1 1745649 R 281310 CDS YP_249323.1 68250211 3431162 1746733..1748124 1 NC_007146.2 Similar to: HI1259, HTOA_HAEIN; periplasmic serine protease do/HhoA-like 1748124 htoA 3431162 htoA Haemophilus influenzae 86-028NP periplasmic serine protease do/HhoA-like YP_249323.1 1746733 D 281310 CDS YP_249324.1 68250212 3431163 complement(1748177..1751617) 1 NC_007146.2 TRCF; Similar to: HI1258, MFD_HAEIN; transcription-repair coupling factor 1751617 mfd 3431163 mfd Haemophilus influenzae 86-028NP transcription-repair coupling factor YP_249324.1 1748177 R 281310 CDS YP_249325.1 68250213 3431164 complement(1751719..1751892) 1 NC_007146.2 Similar to: HI1257, YC57_HAEIN; hypothetical protein 1751892 3431164 NTHI1907 Haemophilus influenzae 86-028NP hypothetical protein YP_249325.1 1751719 R 281310 CDS YP_249326.1 68250214 3431165 complement(1751889..1753859) 1 NC_007146.2 Similar to: HI1254, YC54_HAEIN; P-loop ATPase fused to an acetyltransferase 1753859 3431165 NTHI1908 Haemophilus influenzae 86-028NP P-loop ATPase fused to an acetyltransferase YP_249326.1 1751889 R 281310 CDS YP_249327.1 68250215 3431166 complement(1753864..1754205) 1 NC_007146.2 Similar to: HI1253, YC53_HAEIN; hypothetical protein 1754205 3431166 NTHI1910 Haemophilus influenzae 86-028NP hypothetical protein YP_249327.1 1753864 R 281310 CDS YP_249328.1 68250216 3431167 complement(1754267..1755937) 1 NC_007146.2 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 1755937 3431167 NTHI1911 Haemophilus influenzae 86-028NP ABC transporter ATP-binding protein YP_249328.1 1754267 R 281310 CDS YP_249329.1 68250217 3431168 complement(1756100..1756423) 1 NC_007146.2 Similar to: HI1251, YC51_HAEIN; plasmid maintenance system antidote protein 1756423 3431168 NTHI1912 Haemophilus influenzae 86-028NP plasmid maintenance system antidote protein YP_249329.1 1756100 R 281310 CDS YP_249330.1 68250218 3431169 complement(1756434..1756739) 1 NC_007146.2 Similar to: HI1250, YC50_HAEIN; plasmid maintenance system killer protein 1756739 3431169 NTHI1913 Haemophilus influenzae 86-028NP plasmid maintenance system killer protein YP_249330.1 1756434 R 281310 CDS YP_249331.1 68250219 3431170 1757064..1757684 1 NC_007146.2 Similar to: HI1249, YC49_HAEIN; ABC transporter periplasmic component 1757684 3431170 NTHI1914 Haemophilus influenzae 86-028NP ABC transporter periplasmic component YP_249331.1 1757064 D 281310 CDS YP_249332.1 68250220 3431171 1757687..1758655 1 NC_007146.2 Similar to: HI1248, YC48_HAEIN; ABC transporter permease 1758655 3431171 NTHI1915 Haemophilus influenzae 86-028NP ABC transporter permease YP_249332.1 1757687 D 281310 CDS YP_249333.1 68250221 3431173 1759269..1761308 1 NC_007146.2 UvrB; excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1761308 uvrB 3431173 uvrB Haemophilus influenzae 86-028NP excinuclease ABC subunit B YP_249333.1 1759269 D 281310 CDS YP_249334.1 68250222 3431174 complement(1761338..1763263) 1 NC_007146.2 Similar to: HI1246, YC46_HAEIN; phosphoglycerol transferase-like protein 1763263 3431174 NTHI1918 Haemophilus influenzae 86-028NP phosphoglycerol transferase-like protein YP_249334.1 1761338 R 281310 CDS YP_249335.1 68250223 3431175 complement(1763504..1765774) 1 NC_007146.2 NADP-ME; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 1765774 mao2 3431175 mao2 Haemophilus influenzae 86-028NP malic enzyme YP_249335.1 1763504 R 281310 CDS YP_249336.1 68250224 3431176 1765972..1766592 1 NC_007146.2 Similar to: HI1244, YC44_HAEIN; polysaccharide biosynthesis protein 1766592 3431176 NTHI1921 Haemophilus influenzae 86-028NP polysaccharide biosynthesis protein YP_249336.1 1765972 D 281310 CDS YP_249337.1 68250225 3431177 1766683..1767381 1 NC_007146.2 16S pseudouridylate 516 synthase; 16S pseudouridine 516 synthase; Uracil hydrolyase; Similar to: HI1243, RSUA_HAEIN; ribosomal small subunit pseudouridine synthase A 1767381 rsuA 3431177 rsuA Haemophilus influenzae 86-028NP ribosomal small subunit pseudouridine synthase A YP_249337.1 1766683 D 281310 CDS YP_249338.1 68250226 3431178 1767383..1768579 1 NC_007146.2 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system 1768579 bcr 3431178 bcr Haemophilus influenzae 86-028NP bicyclomycin/multidrug efflux system YP_249338.1 1767383 D 281310 CDS YP_249339.1 68250227 3431179 complement(1768611..1769411) 1 NC_007146.2 Similar to: HI1241, YC41_HAEIN; hypothetical protein 1769411 3431179 NTHI1924 Haemophilus influenzae 86-028NP hypothetical protein YP_249339.1 1768611 R 281310 CDS YP_249340.1 68250228 3431180 1769509..1770171 1 NC_007146.2 Similar to: HI1240, YICG_HAEIN; hypothetical protein 1770171 3431180 NTHI1925 Haemophilus influenzae 86-028NP hypothetical protein YP_249340.1 1769509 D 281310 CDS YP_249341.1 68250229 3431181 1770192..1771445 1 NC_007146.2 GPR; glutamate-5-semialdehyde dehydrogenase; glutamyl-gamma-semialdehyde dehydrogenase; GSA dehydrogenase; Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1771445 proA 3431181 proA Haemophilus influenzae 86-028NP gamma-glutamyl phosphate reductase YP_249341.1 1770192 D 281310 CDS YP_249342.1 68250230 3431182 complement(1771524..1772669) 1 NC_007146.2 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 1772669 dnaJ 3431182 dnaJ Haemophilus influenzae 86-028NP molecular chaperone DnaJ YP_249342.1 1771524 R 281310 CDS YP_249343.1 68250231 3431183 complement(1772756..1774663) 1 NC_007146.2 Heat shock protein 70; Heat shock 70 kDa protein; HSP70; heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1774663 dnaK 3431183 dnaK Haemophilus influenzae 86-028NP molecular chaperone DnaK YP_249343.1 1772756 R 281310 CDS YP_249344.1 68250232 3431184 1774930..1776372 1 NC_007146.2 Similar to: HI1236, YC36_HAEIN; hypothetical protein 1776372 3431184 NTHI1930 Haemophilus influenzae 86-028NP hypothetical protein YP_249344.1 1774930 D 281310 CDS YP_249345.1 68250233 3431185 complement(1776529..1776987) 1 NC_007146.2 MGS; catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1776987 mgsA 3431185 mgsA Haemophilus influenzae 86-028NP methylglyoxal synthase YP_249345.1 1776529 R 281310 CDS YP_249346.1 68250234 3431186 1777287..1779947 1 NC_007146.2 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 1779947 aceE 3431186 aceE Haemophilus influenzae 86-028NP pyruvate dehydrogenase subunit E1 YP_249346.1 1777287 D 281310 CDS YP_249347.1 68250235 3431187 1780010..1781707 1 NC_007146.2 E2; Similar to: HI1232, ODP2_HAEIN; dihydrolipoamide acetyltransferase 1781707 aceF 3431187 aceF Haemophilus influenzae 86-028NP dihydrolipoamide acetyltransferase YP_249347.1 1780010 D 281310 CDS YP_249348.1 68250236 3431188 1781821..1783245 1 NC_007146.2 E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes; E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1783245 lpdA 3431188 lpdA Haemophilus influenzae 86-028NP dihydrolipoamide dehydrogenase YP_249348.1 1781821 D 281310 CDS YP_249349.1 68250237 3431189 complement(1783292..1783399) 1 NC_007146.2 hypothetical protein 1783399 3431189 NTHI1936 Haemophilus influenzae 86-028NP hypothetical protein YP_249349.1 1783292 R 281310 CDS YP_249350.1 68250238 3431190 1783405..1783947 1 NC_007146.2 APRT; catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1783947 apt 3431190 apt Haemophilus influenzae 86-028NP adenine phosphoribosyltransferase YP_249350.1 1783405 D 281310 CDS YP_249351.1 68250239 3431191 1783959..1786025 1 NC_007146.2 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1786025 dnaX 3431191 dnaX Haemophilus influenzae 86-028NP DNA polymerase III subunits gamma and tau YP_249351.1 1783959 D 281310 CDS YP_249352.1 68250240 3431192 1786165..1786791 1 NC_007146.2 UMP pyrophosphorylase; UPRTase; Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 1786791 upp 3431192 upp Haemophilus influenzae 86-028NP uracil phosphoribosyltransferase YP_249352.1 1786165 D 281310 CDS YP_249353.1 68250241 3431193 1786895..1788139 1 NC_007146.2 Uracil transporter; Similar to: HI1227, URAA_HAEIN; uracil permease 1788139 uraA 3431193 uraA Haemophilus influenzae 86-028NP uracil permease YP_249353.1 1786895 D 281310 CDS YP_249354.1 68250242 3431194 1788205..1788900 1 NC_007146.2 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 1788900 3431194 NTHI1942 Haemophilus influenzae 86-028NP DNA replication initiation factor YP_249354.1 1788205 D 281310 CDS YP_249355.1 68250243 3431195 complement(1788967..1789248) 1 NC_007146.2 Similar to: HI1225, YCIH_HAEIN; translation initiation factor 1-like proterin 1789248 3431195 NTHI1943 Haemophilus influenzae 86-028NP translation initiation factor 1-like proterin YP_249355.1 1788967 R 281310 CDS YP_249356.1 68250244 3431196 complement(1789255..1789947) 1 NC_007146.2 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1789947 pyrF 3431196 pyrF Haemophilus influenzae 86-028NP orotidine 5'-phosphate decarboxylase YP_249356.1 1789255 R 281310 CDS YP_249357.1 68250245 3431197 complement(1789971..1791161) 1 NC_007146.2 Similar to: HI1223, YCIM_HAEIN; tetratricopeptide repeat protein 1791161 3431197 NTHI1945 Haemophilus influenzae 86-028NP tetratricopeptide repeat protein YP_249357.1 1789971 R 281310 CDS YP_249358.1 68250246 3431198 complement(1791161..1791454) 1 NC_007146.2 Similar to: HI1222, YCIS_HAEIN; hypothetical protein 1791454 3431198 NTHI1946 Haemophilus influenzae 86-028NP hypothetical protein YP_249358.1 1791161 R 281310 CDS YP_249359.1 68250247 3431199 complement(1791529..1791813) 1 NC_007146.2 IHF-beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1791813 ihfB 3431199 ihfB Haemophilus influenzae 86-028NP integration host factor subunit beta YP_249359.1 1791529 R 281310 CDS YP_249360.1 68250248 3431200 complement(1791936..1793585) 1 NC_007146.2 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1793585 rpsA 3431200 rpsA Haemophilus influenzae 86-028NP 30S ribosomal protein S1 YP_249360.1 1791936 R 281310 CDS YP_249361.1 68250249 3431201 complement(1793688..1794482) 1 NC_007146.2 CK; cytidine monophosphate kinase; CMP kinase; Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1794482 cmk 3431201 cmk Haemophilus influenzae 86-028NP cytidylate kinase YP_249361.1 1793688 R 281310 CDS YP_249362.1 68250250 3431202 1794828..1795703 1 NC_007146.2 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 1795703 3431202 NTHI1950 Haemophilus influenzae 86-028NP pyridoxal biosynthesis lyase PdxS YP_249362.1 1794828 D 281310 CDS YP_249363.1 68250251 3431203 1795704..1796282 1 NC_007146.2 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 1796282 3431203 NTHI1951 Haemophilus influenzae 86-028NP glutamine amidotransferase subunit PdxT YP_249363.1 1795704 D 281310 CDS YP_249364.1 68250252 3431204 complement(1796831..1798525) 1 NC_007146.2 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 1798525 dld 3431204 dld Haemophilus influenzae 86-028NP D-lactate dehydrogenase YP_249364.1 1796831 R 281310 CDS YP_249365.1 68250253 3431205 1798785..1798895 1 NC_007146.2 Similar to: HI1650; hypothetical protein 1798895 3431205 NTHI1953 Haemophilus influenzae 86-028NP hypothetical protein YP_249365.1 1798785 D 281310 CDS YP_249366.1 68250254 3431206 complement(1799430..1799981) 1 NC_007146.2 Similar to: HI1652, NLPC_HAEIN; lipoprotein NlpC 1799981 nlpC 3431206 nlpC Haemophilus influenzae 86-028NP lipoprotein NlpC YP_249366.1 1799430 R 281310 CDS YP_249367.1 68250255 3431207 complement(1800094..1801542) 1 NC_007146.2 Similar to: TLDD_HAEIN; hypothetical protein 1801542 tldD 3431207 tldD Haemophilus influenzae 86-028NP hypothetical protein YP_249367.1 1800094 R 281310 CDS YP_249368.1 68250256 3431208 complement(1801644..1802495) 1 NC_007146.2 Similar to: HI1654, YRAL_HAEIN; methyltransferase 1802495 3431208 NTHI1956 Haemophilus influenzae 86-028NP methyltransferase YP_249368.1 1801644 R 281310 CDS YP_249369.1 68250257 3431209 1802567..1804294 1 NC_007146.2 Similar to: HI1655, YRAM_HAEIN; lipoprotein 1804294 3431209 NTHI1957 Haemophilus influenzae 86-028NP lipoprotein YP_249369.1 1802567 D 281310 CDS YP_249370.1 68250258 3431210 1804294..1804653 1 NC_007146.2 Similar to: HI1656, YG56_HAEIN; hypothetical protein 1804653 3431210 NTHI1958 Haemophilus influenzae 86-028NP hypothetical protein YP_249370.1 1804294 D 281310 CDS YP_249371.1 68250259 3431211 1804666..1805250 1 NC_007146.2 Similar to: HI1657, YRAO_HAEIN; hypothetical protein 1805250 3431211 NTHI1959 Haemophilus influenzae 86-028NP hypothetical protein YP_249371.1 1804666 D 281310 CDS YP_249372.1 68250260 3431212 1805307..1805888 1 NC_007146.2 Similar to: HI1658, YRAP_HAEIN; hypothetical protein 1805888 3431212 NTHI1960 Haemophilus influenzae 86-028NP hypothetical protein YP_249372.1 1805307 D 281310 CDS YP_249373.1 68250261 3431213 1806143..1808413 1 NC_007146.2 ribonucleotide reductase; Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1808413 nrdA 3431213 nrdA Haemophilus influenzae 86-028NP ribonucleotide-diphosphate reductase subunit alpha YP_249373.1 1806143 D 281310 CDS YP_249374.1 68250262 3431214 1808555..1809685 1 NC_007146.2 ribonucleotide reductase small subunit; B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 1809685 nrdB 3431214 nrdB Haemophilus influenzae 86-028NP ribonucleotide-diphosphate reductase subunit beta YP_249374.1 1808555 D 281310 CDS YP_249375.1 68250263 3431215 complement(1809801..1811030) 1 NC_007146.2 E2; Similar to: HI1661, ODO2_HAEIN; dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex 1811030 sucB 3431215 sucB Haemophilus influenzae 86-028NP dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex YP_249375.1 1809801 R 281310 CDS YP_249376.1 68250264 3431216 complement(1811133..1813985) 1 NC_007146.2 alpha-ketoglutarate dehydrogenase; SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 1813985 sucA 3431216 sucA Haemophilus influenzae 86-028NP 2-oxoglutarate dehydrogenase E1 YP_249376.1 1811133 R 281310 CDS YP_249377.1 68250265 3431217 complement(1814143..1814781) 1 NC_007146.2 Similar to: HI1663, YCBL_HAEIN; Zn-dependent hydrolase 1814781 3431217 NTHI1965 Haemophilus influenzae 86-028NP Zn-dependent hydrolase YP_249377.1 1814143 R 281310 CDS YP_249378.1 68250266 3431218 complement(1814791..1815546) 1 NC_007146.2 Similar to: HI1664, YG64_HAEIN; deoxyribonuclease 1815546 3431218 NTHI1966 Haemophilus influenzae 86-028NP deoxyribonuclease YP_249378.1 1814791 R 281310 CDS YP_249379.1 68250267 3431219 complement(1815598..1816158) 1 NC_007146.2 Similar to: HI1666, YCBK_HAEIN; hypothetical protein 1816158 3431219 NTHI1967 Haemophilus influenzae 86-028NP hypothetical protein YP_249379.1 1815598 R 281310 CDS YP_249380.1 68250268 3431220 complement(1816174..1817643) 1 NC_007146.2 Similar to: HI1667, YCBB_HAEIN; hypothetical protein 1817643 3431220 NTHI1968 Haemophilus influenzae 86-028NP hypothetical protein YP_249380.1 1816174 R 281310 CDS YP_249381.1 68250269 3431221 complement(1817717..1819804) 1 NC_007146.2 protease Re; C-terminal processing peptidase; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 1819804 prc 3431221 prc Haemophilus influenzae 86-028NP carboxy-terminal protease YP_249381.1 1817717 R 281310 CDS YP_249382.1 68250270 3431222 complement(1819826..1820464) 1 NC_007146.2 affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 1820464 proQ 3431222 proQ Haemophilus influenzae 86-028NP solute/DNA competence effector YP_249382.1 1819826 R 281310 CDS YP_249383.1 68250271 3431223 1820649..1821899 1 NC_007146.2 Similar to: HI1671, YEBS_HAEIN; paraquat-inducible protein A-like protein 1821899 3431223 NTHI1972 Haemophilus influenzae 86-028NP paraquat-inducible protein A-like protein YP_249383.1 1820649 D 281310 CDS YP_249384.1 68250272 3431224 1821883..1824528 1 NC_007146.2 Similar to: HI1672, YEBT_HAEIN; paraquat-inducible protein B-like protein 1824528 3431224 NTHI1973 Haemophilus influenzae 86-028NP paraquat-inducible protein B-like protein YP_249384.1 1821883 D 281310 CDS YP_249385.1 68250273 3431225 complement(1824583..1825035) 1 NC_007146.2 MPT synthase subunit 2; molybdopterin synthase subunit 2; molybdenum cofactor biosynthesis protein E; molybdopterin converting factor large subunit; Similar to: HI1673, MOAE_HAEIN; molybdopterin converting factor subunit 2 1825035 moaE 3431225 moaE Haemophilus influenzae 86-028NP molybdopterin converting factor subunit 2 YP_249385.1 1824583 R 281310 CDS YP_249386.1 68250274 3431226 complement(1825036..1825281) 1 NC_007146.2 MPT synthase subunit 1; molybdopterin synthase subunit 1; molybdenum cofactor biosynthesis protein D; molybdopterin converting factor small subunit; catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 1825281 moaD 3431226 moaD Haemophilus influenzae 86-028NP molybdopterin synthase small subunit YP_249386.1 1825036 R 281310 CDS YP_249387.1 68250275 3431227 complement(1825283..1825765) 1 NC_007146.2 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 1825765 moaC 3431227 moaC Haemophilus influenzae 86-028NP molybdenum cofactor biosynthesis protein MoaC YP_249387.1 1825283 R 281310 CDS YP_249388.1 68250276 3431228 complement(1825857..1826870) 1 NC_007146.2 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 1826870 moaA 3431228 moaA Haemophilus influenzae 86-028NP molybdenum cofactor biosynthesis protein A YP_249388.1 1825857 R 281310 CDS YP_249389.1 68250277 3431229 1827315..1827788 1 NC_007146.2 Similar to: HI1677, YTFE_HAEIN; regulator of cell morphogenesis and NO signaling 1827788 3431229 NTHI1979 Haemophilus influenzae 86-028NP regulator of cell morphogenesis and NO signaling YP_249389.1 1827315 D 281310 CDS YP_249390.1 68250278 3431230 1827788..1827985 1 NC_007146.2 Similar to: HI1677, YTFE_HAEIN; regulator of cell morphogenesis and NO signaling 1827985 3431230 NTHI1980 Haemophilus influenzae 86-028NP regulator of cell morphogenesis and NO signaling YP_249390.1 1827788 D 281310 CDS YP_249391.1 68250279 3431231 1828522..1829535 1 NC_007146.2 Similar to: HI1678, YG78_HAEIN; arabinose-5-phosphate isomerase 1829535 3431231 NTHI1981 Haemophilus influenzae 86-028NP arabinose-5-phosphate isomerase YP_249391.1 1828522 D 281310 CDS YP_249392.1 68250280 3431232 1829545..1830087 1 NC_007146.2 KDO 8-P phosphatase; Similar to: HI1679, KDOP_HAEIN; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 1830087 yrbI 3431232 yrbI Haemophilus influenzae 86-028NP 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_249392.1 1829545 D 281310 CDS YP_249393.1 68250281 3431233 1830518..1834996 1 NC_007146.2 HMW1A, high molecular weight adhesin 1 1834996 hmw1A 3431233 hmw1A Haemophilus influenzae 86-028NP HMW1A, high molecular weight adhesin 1 YP_249393.1 1830518 D 281310 CDS YP_249394.1 68250282 3431234 1835147..1836784 1 NC_007146.2 HMW1B, OMP-85-like protein required for secretion of HMW1A and HMW2A 1836784 hmw1B 3431234 hmw1B Haemophilus influenzae 86-028NP HMW1B, OMP-85-like protein required for secretion of HMW1A and HMW2A YP_249394.1 1835147 D 281310 CDS YP_249395.1 68250283 3431235 1836978..1838930 1 NC_007146.2 HMW1C, glycosyltransferase involved in glycosylation of HMW1A and HMW2A 1838930 hmw1C 3431235 hmw1C Haemophilus influenzae 86-028NP HMW1C, glycosyltransferase involved in glycosylation of HMW1A and HMW2A YP_249395.1 1836978 D 281310 CDS YP_249396.1 68250284 3431236 complement(1839007..1841163) 1 NC_007146.2 Similar to: HI1680, YCCS_HAEIN; hypothetical protein 1841163 3431236 NTHI1986 Haemophilus influenzae 86-028NP hypothetical protein YP_249396.1 1839007 R 281310 CDS YP_249397.1 68250285 3431237 complement(1841231..1841896) 1 NC_007146.2 Similar to: HI1681, YG81_HAEIN; hypothetical protein 1841896 3431237 NTHI1987 Haemophilus influenzae 86-028NP hypothetical protein YP_249397.1 1841231 R 281310 CDS YP_249398.1 68250286 3431238 1842094..1843155 1 NC_007146.2 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1843155 sohB 3431238 sohB Haemophilus influenzae 86-028NP periplasmic protease YP_249398.1 1842094 D 281310 CDS YP_249399.1 68250287 3431239 1843439..1844017 1 NC_007146.2 Similar to: HI1683, RNFA_HAEIN; Na(+)-translocating NADH-quinone reductase subunit E 1844017 rnfA 3431239 rnfA Haemophilus influenzae 86-028NP Na(+)-translocating NADH-quinone reductase subunit E YP_249399.1 1843439 D 281310 CDS YP_249400.1 68250288 3431240 1844105..1844686 1 NC_007146.2 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1844686 rnfB 3431240 rnfB Haemophilus influenzae 86-028NP electron transport complex protein RnfB YP_249400.1 1844105 D 281310 CDS YP_249401.1 68250289 3431241 1844687..1846684 1 NC_007146.2 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1846684 rnfC 3431241 rnfC Haemophilus influenzae 86-028NP electron transport complex protein RnfC YP_249401.1 1844687 D 281310 CDS YP_249402.1 68250290 3431242 1846814..1847890 1 NC_007146.2 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1847890 rnfD 3431242 rnfD Haemophilus influenzae 86-028NP electron transport complex protein RnfD YP_249402.1 1846814 D 281310 CDS YP_249403.1 68250291 3431243 1847890..1848513 1 NC_007146.2 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1848513 rnfG 3431243 rnfG Haemophilus influenzae 86-028NP electron transport complex protein RnfG YP_249403.1 1847890 D 281310 CDS YP_249404.1 68250292 3431244 1848515..1849222 1 NC_007146.2 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 1849222 3431244 NTHI1995 Haemophilus influenzae 86-028NP electron transport complex RsxE subunit YP_249404.1 1848515 D 281310 CDS YP_249405.1 68250293 3431245 1849344..1849979 1 NC_007146.2 DNA-(apurinic or apyrimidinic site) lyase; Similar to: HI1689, END3_HAEIN; endonuclease III 1849979 nth 3431245 nth Haemophilus influenzae 86-028NP endonuclease III YP_249405.1 1849344 D 281310 CDS YP_249406.1 68250294 3431246 1850038..1851411 1 NC_007146.2 Similar to: HI1690, YG90_HAEIN; SNF family Na+-dependent transporter 1851411 3431246 NTHI1997 Haemophilus influenzae 86-028NP SNF family Na+-dependent transporter YP_249406.1 1850038 D 281310 CDS YP_249407.1 68250295 3431247 complement(1851435..1852490) 1 NC_007146.2 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 1852490 modC 3431247 modC Haemophilus influenzae 86-028NP molybdate transporter ATP-binding protein YP_249407.1 1851435 R 281310 CDS YP_249408.1 68250296 3431248 complement(1852477..1853166) 1 NC_007146.2 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease protein 1853166 modB 3431248 modB Haemophilus influenzae 86-028NP molybdate ABC transporter permease protein YP_249408.1 1852477 R 281310 CDS YP_249409.1 68250297 3431249 complement(1853340..1854104) 1 NC_007146.2 Similar to: HI1693, MODA_HAEIN; molybdate-binding periplasmic protein 1854104 modA 3431249 modA Haemophilus influenzae 86-028NP molybdate-binding periplasmic protein YP_249409.1 1853340 R 281310 CDS YP_249410.1 68250298 3431250 1854242..1855009 1 NC_007146.2 Similar to: HI1694, MODE_HAEIN; transcriptional regulator ModE 1855009 modE 3431250 modE Haemophilus influenzae 86-028NP transcriptional regulator ModE YP_249410.1 1854242 D 281310 CDS YP_249411.1 68250299 3431251 complement(1855119..1855922) 1 NC_007146.2 Similar to: HI1695, YG95_HAEIN; UDP-galactose--lipooligosaccharide galactosyltransferase 1855922 lsgF 3431251 lsgF Haemophilus influenzae 86-028NP UDP-galactose--lipooligosaccharide galactosyltransferase YP_249411.1 1855119 R 281310 CDS YP_249412.1 68250300 3431252 complement(1855924..1856808) 1 NC_007146.2 Similar to: HI1696, YG96_HAEIN; UDP-galactose--lipooligosaccharide galactosyltransferase 1856808 lsgE 3431252 lsgE Haemophilus influenzae 86-028NP UDP-galactose--lipooligosaccharide galactosyltransferase YP_249412.1 1855924 R 281310 CDS YP_249413.1 68250301 3431253 complement(1856820..1857593) 1 NC_007146.2 Similar to: HI1697, LSG4_HAEIN; UDP-GlcNAc--lipooligosaccharide N-acetylglucosaminyl glycosyltransferase 1857593 lsgD 3431253 lsgD Haemophilus influenzae 86-028NP UDP-GlcNAc--lipooligosaccharide N-acetylglucosaminyl glycosyltransferase YP_249413.1 1856820 R 281310 CDS YP_249414.1 68250302 3431254 complement(1857605..1858666) 1 NC_007146.2 Similar to: HI1698, YG98_HAEIN; UDP-galactose--lipooligosaccharide galactosyltransferase 1858666 lsgC 3431254 lsgC Haemophilus influenzae 86-028NP UDP-galactose--lipooligosaccharide galactosyltransferase YP_249414.1 1857605 R 281310 CDS YP_249415.1 68250303 3431255 complement(1858668..1859582) 1 NC_007146.2 beta-galactoside alpha-2,3-sialyltransferase; Alpha 2,3-ST; lipooligosaccharide sialyltransferase; Similar to: HI1699, LST_HAEIN; CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1859582 lsgB 3431255 lsgB Haemophilus influenzae 86-028NP CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase YP_249415.1 1858668 R 281310 CDS YP_249416.1 68250304 3431256 complement(1859579..1860784) 1 NC_007146.2 Similar to: HI1700, LSG1_HAEIN; lipooligosaccharide flippase 1860784 lsgA 3431256 lsgA Haemophilus influenzae 86-028NP lipooligosaccharide flippase YP_249416.1 1859579 R 281310 CDS YP_249417.1 68250305 3431257 1860919..1861662 1 NC_007146.2 Similar to: HI1701, YH01_HAEIN; hypothetical protein 1861662 3431257 NTHI2008 Haemophilus influenzae 86-028NP hypothetical protein YP_249417.1 1860919 D 281310 CDS YP_249418.1 68250306 3431259 complement(1864348..1865424) 1 NC_007146.2 Similar to: HI1703, YJGQ_HAEIN; permease 1865424 3431259 NTHI2011 Haemophilus influenzae 86-028NP permease YP_249418.1 1864348 R 281310 CDS YP_249419.1 68250307 3431260 complement(1865421..1866524) 1 NC_007146.2 Similar to: HI1704, YJGP_HAEIN; permease 1866524 3431260 NTHI2012 Haemophilus influenzae 86-028NP permease YP_249419.1 1865421 R 281310 CDS YP_249420.1 68250308 3431261 1866632..1868107 1 NC_007146.2 aminopeptidase A; leucine aminopeptidase; LAP; Leucyl aminopeptidase; catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 1868107 pepA 3431261 pepA Haemophilus influenzae 86-028NP leucyl aminopeptidase YP_249420.1 1866632 D 281310 CDS YP_249421.1 68250309 3431262 complement(1868143..1870152) 1 NC_007146.2 Similar to: HI1706, YH06_HAEIN; choline-glycine betaine transporter 1870152 3431262 NTHI2014 Haemophilus influenzae 86-028NP choline-glycine betaine transporter YP_249421.1 1868143 R 281310 CDS YP_249422.1 68250310 3431263 complement(1870447..1871802) 1 NC_007146.2 Similar to: HI1707, QSEC_HAEIN; sensor protein QseC 1871802 qseC 3431263 qseC Haemophilus influenzae 86-028NP sensor protein QseC YP_249422.1 1870447 R 281310 CDS YP_249423.1 68250311 3431264 complement(1871799..1872464) 1 NC_007146.2 Similar to: HI1708, QSEB_HAEIN; transcriptional regulatory protein 1872464 qseB 3431264 qseB Haemophilus influenzae 86-028NP transcriptional regulatory protein YP_249423.1 1871799 R 281310 CDS YP_249424.1 68250312 3431265 complement(1872528..1872893) 1 NC_007146.2 Similar to: HI1709, YGIW_HAEIN; hypothetical protein 1872893 3431265 NTHI2017 Haemophilus influenzae 86-028NP hypothetical protein YP_249424.1 1872528 R 281310 CDS YP_249425.1 68250313 3431267 complement(1874398..1874898) 1 NC_007146.2 EIIA-Glc; glucose-permease IIA component; phosphotransferase enzyme II, A component; EIII-Glc; functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit 1874898 crr 3431267 crr Haemophilus influenzae 86-028NP PTS system glucose-specific transporter subunit YP_249425.1 1874398 R 281310 CDS YP_249426.1 68250314 3431268 complement(1874958..1876685) 1 NC_007146.2 phosphotransferase system, enzyme I; Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 1876685 ptsI 3431268 ptsI Haemophilus influenzae 86-028NP phosphoenolpyruvate-protein phosphotransferase YP_249426.1 1874958 R 281310 CDS YP_249427.1 68250315 3431269 complement(1876765..1877022) 1 NC_007146.2 histidine-containing protein; Similar to: HI1713, PTHP_HAEIN; phosphocarrier protein HPr 1877022 ptsH 3431269 ptsH Haemophilus influenzae 86-028NP phosphocarrier protein HPr YP_249427.1 1876765 R 281310 CDS YP_249428.1 68250316 3431270 complement(1877181..1878221) 1 NC_007146.2 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 1878221 engC 3431270 engC Haemophilus influenzae 86-028NP ribosome-associated GTPase YP_249428.1 1877181 R 281310 CDS YP_249429.1 68250317 3431271 1878292..1878840 1 NC_007146.2 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1878840 orn 3431271 orn Haemophilus influenzae 86-028NP oligoribonuclease YP_249429.1 1878292 D 281310 CDS YP_249430.1 68250318 3431274 complement(1879240..1880307) 1 NC_007146.2 Similar to: HI1716, RFE_HAEIN; undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase 1880307 wecA 3431274 wecA Haemophilus influenzae 86-028NP undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase YP_249430.1 1879240 R 281310 CDS YP_249431.1 68250319 3431275 complement(1880382..1882973) 1 NC_007146.2 PII uridylyl-transferase; uridylyl removing enzyme; UTase; Similar to: HI1719, GLND_HAEIN; PII uridylyl-transferase 1882973 glnD 3431275 glnD Haemophilus influenzae 86-028NP PII uridylyl-transferase YP_249431.1 1880382 R 281310 CDS YP_249432.1 68250320 3431276 complement(1883067..1883873) 1 NC_007146.2 MAP; peptidase M; catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1883873 map 3431276 map Haemophilus influenzae 86-028NP methionine aminopeptidase YP_249432.1 1883067 R 281310 CDS YP_249433.1 68250321 3431277 1884009..1884353 1 NC_007146.2 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 1884353 3431277 NTHI2029 Haemophilus influenzae 86-028NP iron-sulfur cluster insertion protein ErpA YP_249433.1 1884009 D 281310 CDS YP_249434.1 68250322 3431278 1884355..1884708 1 NC_007146.2 Similar to: HI1724, YH24_HAEIN; hypothetical protein 1884708 3431278 NTHI2030 Haemophilus influenzae 86-028NP hypothetical protein YP_249434.1 1884355 D 281310 CDS YP_249435.1 68250323 3431279 1884715..1887060 1 NC_007146.2 PBP-1b; PBP1b; Murein polymerase; peptidoglycan glycosyltransferase; peptidoglycan TGase; DD-transpeptidase; Similar to: HI1725, PBPB_HAEIN; penicillin-binding protein 1B 1887060 mrcB 3431279 mrcB Haemophilus influenzae 86-028NP penicillin-binding protein 1B YP_249435.1 1884715 D 281310 CDS YP_249436.1 68250324 3431280 1887185..1888105 1 NC_007146.2 SAICAR synthetase; catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1888105 hemH 3431280 hemH Haemophilus influenzae 86-028NP phosphoribosylaminoimidazole-succinocarboxamide synthase YP_249436.1 1887185 D 281310 CDS YP_249437.1 68250325 3431281 1888261..1889595 1 NC_007146.2 citrulline--aspartate ligase; catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 1889595 argG 3431281 argG Haemophilus influenzae 86-028NP argininosuccinate synthase YP_249437.1 1888261 D 281310 CDS YP_249438.1 68250326 3431282 complement(1889666..1890859) 1 NC_007146.2 Similar to: HI1728, YH28_HAEIN; manganese transporter NRAMP 1890859 3431282 NTHI2035 Haemophilus influenzae 86-028NP manganese transporter NRAMP YP_249438.1 1889666 R 281310 CDS YP_249439.1 68250327 3431283 complement(1890903..1891640) 1 NC_007146.2 Similar to: HI1729, YH29_HAEIN; LamB/YcsF family protein 1891640 3431283 NTHI2036 Haemophilus influenzae 86-028NP LamB/YcsF family protein YP_249439.1 1890903 R 281310 CDS YP_249440.1 68250328 3431284 complement(1891627..1892556) 1 NC_007146.2 Similar to: HI1730, YBGK_HAEIN; allophanate hydrolase subunit 2 1892556 3431284 NTHI2037 Haemophilus influenzae 86-028NP allophanate hydrolase subunit 2 YP_249440.1 1891627 R 281310 CDS YP_249441.1 68250329 3431285 complement(1892553..1893194) 1 NC_007146.2 Similar to: HI1731, YBGJ_HAEIN; allophanate hydrolase subunit 1 1893194 3431285 NTHI2038 Haemophilus influenzae 86-028NP allophanate hydrolase subunit 1 YP_249441.1 1892553 R 281310 CDS YP_249442.1 68250330 3431286 complement(1893456..1895435) 1 NC_007146.2 ribonuclease II; RNase II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1895435 rnb 3431286 rnb Haemophilus influenzae 86-028NP exoribonuclease II YP_249442.1 1893456 R 281310 CDS YP_249443.1 68250331 3431287 complement(1895533..1896420) 1 NC_007146.2 NADH-dependent enoyl-ACP reductase; Similar to: HI1734, FABI_HAEIN; enoyl-ACP reductase 1896420 fabI 3431287 fabI Haemophilus influenzae 86-028NP enoyl-ACP reductase YP_249443.1 1895533 R 281310 CDS YP_249444.1 68250332 3431288 1896500..1898083 1 NC_007146.2 RF-3; stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 1898083 prfC 3431288 prfC Haemophilus influenzae 86-028NP peptide chain release factor 3 YP_249444.1 1896500 D 281310 CDS YP_249445.1 68250333 3431289 complement(1898159..1898392) 1 NC_007146.2 Similar to: HI1736, YH36_HAEIN; hypothetical protein 1898392 3431289 NTHI2045 Haemophilus influenzae 86-028NP hypothetical protein YP_249445.1 1898159 R 281310 CDS YP_249446.1 68250334 3431290 complement(1898495..1898824) 1 NC_007146.2 Similar to: HI1737, YH37_HAEIN; branched-chain amino acid permease 1898824 3431290 NTHI2046 Haemophilus influenzae 86-028NP branched-chain amino acid permease YP_249446.1 1898495 R 281310 CDS YP_249447.1 68250335 3431291 complement(1898821..1899555) 1 NC_007146.2 Similar to: HI1738, YH38_HAEIN; branched-chain amino acid permease 1899555 3431291 NTHI2047 Haemophilus influenzae 86-028NP branched-chain amino acid permease YP_249447.1 1898821 R 281310 CDS YP_249448.1 68250336 3431292 complement(1899565..1900494) 1 NC_007146.2 Similar to: HI1739, METR_HAEIN; HTH-type transcriptional regulator MetR 1900494 metR 3431292 metR Haemophilus influenzae 86-028NP HTH-type transcriptional regulator MetR YP_249448.1 1899565 R 281310 CDS YP_249449.1 68250337 3431298 complement(1906825..1907970) 1 NC_007146.2 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 1907970 lldD 3431298 lldD Haemophilus influenzae 86-028NP L-lactate dehydrogenase YP_249449.1 1906825 R 281310 CDS YP_249450.1 68250338 3431299 complement(1908182..1908991) 1 NC_007146.2 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1908991 murI 3431299 murI Haemophilus influenzae 86-028NP glutamate racemase YP_249450.1 1908182 R 281310 CDS YP_249451.1 68250339 3431300 complement(1909021..1911102) 1 NC_007146.2 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1911102 recG 3431300 recG Haemophilus influenzae 86-028NP ATP-dependent DNA helicase RecG YP_249451.1 1909021 R 281310 CDS YP_249452.1 68250340 3431301 complement(1911099..1913213) 1 NC_007146.2 diphosphate; (ppGpp)ase; Penta-phosphate guanosine-3'-pyrophosphohydrolase; Similar to: HI1741, SPOT_HAEIN; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 1913213 spoT 3431301 spoT Haemophilus influenzae 86-028NP guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase YP_249452.1 1911099 R 281310 CDS YP_249453.1 68250341 3431302 complement(1913286..1913552) 1 NC_007146.2 transcriptase omega chain; RNA polymerase omega subunit; promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1913552 rpoZ 3431302 rpoZ Haemophilus influenzae 86-028NP DNA-directed RNA polymerase subunit omega YP_249453.1 1913286 R 281310 CDS YP_249454.1 68250342 3431303 complement(1913615..1914241) 1 NC_007146.2 GMP kinase; Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1914241 gmk 3431303 gmk Haemophilus influenzae 86-028NP guanylate kinase YP_249454.1 1913615 R 281310 CDS