-- dump date 20140619_104155 -- class Genbank::CDS -- table cds_note -- id note YP_247664.1 GAPDH; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate YP_247665.1 Long-chain acyl-CoA synthetase; LACS; Similar to: HI0002, LCFH_HAEIN YP_247666.1 Similar to: HI0003, Y003_HAEIN YP_247667.1 Similar to: HI0004, Y004_HAEIN YP_247668.1 protein required for formate dehydrogenase activity; involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_247669.1 formate dehydrogenase alpha subunit; FDH alpha subunit; Similar to: FDXG_HAEIN; Opal (TGA) stop encodes selenocysteine YP_247670.1 formate dehydrogenase beta subunit; FDH beta subunit; Similar to: HI0007, FDXH_HAEIN YP_247671.1 formate dehydrogenase gamma subunit; FDH gamma subunit; Similar to: HI0008, FDXI_HAEIN YP_247672.1 required for the formation of active formate dehydrogenase YP_247673.1 acetylating enzyme for N-terminal of ribosomal protein S18; alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_247674.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_247675.1 rRNA (guanine-N(2)-)-methyltransferase; 16S rRNA m2G1207 methyltransferase; 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_247676.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_247677.1 RNase III; cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_247678.1 SPase I; Leader peptidase I; Similar to: HI0015, LEP_HAEIN YP_247679.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_247680.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_247681.1 UDG; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_247682.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_247683.1 Similar to: HI0020, YBHI_HAEIN YP_247684.1 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase; Holo-citrate lyase synthase; Apo-ACP nucleodityltransferase; Similar to: HI0021, CIXG_HAEIN YP_247685.1 citrase; citrate CoA-transferase subunit; Similar to: HI0022, CILA_HAEIN YP_247686.1 citrase; Citryl-CoA lyase subunit; Similar to: HI0023, CILB_HAEIN YP_247687.1 citrate lyase gamma chain; acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_247688.1 citrate lyase synthetase; acetate:SH-citrate lyase ligase; Similar to: HI0025, CITC_HAEIN YP_247689.1 Lip-syn; lipoate synthase; catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_247690.1 lipoate biosynthesis protein B; lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_247691.1 Similar to: HI0028, Y028_HAEIN YP_247692.1 D-alanyl-D-alanine carboxypeptidase fraction A; DD-peptidase; DD-carboxypeptidase; PBP-5; Similar to: HI0029, DACA_HAEIN YP_247693.1 Similar to: HI0030, RLPA_HAEIN YP_247694.1 Similar to: HI0031, RODA_HAEIN YP_247695.1 PBP-2; Similar to: HI0032, PBP2_HAEIN YP_247696.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_247697.1 Similar to: HI0034, YBEB_HAEIN YP_247698.1 Similar to: HI0035, Y035_HAEIN YP_247699.1 Similar to: HI0036, Y036_HAEIN YP_247700.2 functions in MreBCD complex in some organisms YP_247701.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_247702.1 Similar to: HI0039, MRED_HAEIN YP_247703.1 Similar to: HI0040, Y040_HAEIN YP_247704.1 exonuclease III; EXO III; removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_247705.1 pseudouridylate synthase; Uracil hydrolyase; Similar to: HI0042, Y042_HAEIN YP_247706.1 Similar to: HI0043, Y043_HAEIN YP_247707.1 Similar to: HI0044, YCCA_HAEIN YP_247708.1 Similar to: HI0045, YTFJ_HAEIN YP_247709.1 Similar to: HI0046, PHNA_HAEIN YP_247710.1 2-keto-4-hydroxyglutarate aldolase; KHG-aldolase; phospho-2-dehydro-3-deoxygluconate aldolase; phospho-2-keto-3-deoxygluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; KDPG-aldolase; catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_247711.1 glucuronate isomerase; Uronic isomerase; catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_247712.1 Converts D-mannonate to D-mannuronate YP_247713.1 Similar to: HI0050, Y050_HAEIN YP_247714.1 Similar to: HI0051, Y051_HAEIN YP_247715.1 Similar to: HI0052, Y052_HAEIN YP_247716.1 Similar to: HI0053, Y053_HAEIN YP_247717.1 Similar to: HI0054, UXUR_HAEIN YP_247718.1 D-mannonate hydrolase; catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_247719.1 possibly involved in tellurium resistance; Similar to: HI0056, YGDQ_HAEIN YP_247720.1 UvrC; excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_247721.1 CMP-KDO synthetase; CMP-2-keto-3-deoxyoctulosonic acid synthetase; CKS; CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_247722.1 lipid A 4'-kinase; transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_247723.1 involved in the transport of lipid A across the inner membrane YP_247724.1 Similar to: HI0061, REC2_HAEIN YP_247725.1 Similar to: HI0062, DKSA_HAEIN YP_247726.1 Similar to: HI0063, PCNB_HAEIN YP_247727.1 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; HPPK; 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; PPPK; Similar to: HI0064, HPPK_HAEIN YP_247728.1 Similar to: HI0065, YJEE_HAEIN; predicted ATPase activity YP_247729.1 Similar to: HI0066, AMIB_HAEIN YP_247730.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_247731.1 IPP transferase; isopentenyl-diphosphate:tRNA isopentenyltransferase; IPTase; IPPT; IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_247732.1 glutamine-synthetase adenylyltransferase; ATASE; catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_247733.1 recombination protein N; Similar to: HI0070, RECN_HAEIN YP_247734.1 Poly(P)/ATP NAD kinase; catalyzes the phosphorylation of NAD to NADP YP_247735.1 HSP-70 cofactor; with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_247736.1 Similar to: HI0073, Y073_HAEIN; nucleotidyltransferase family YP_247737.1 Similar to: HI0074, Y074_HAEIN; nucleotidyltransferase family YP_247738.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_247739.1 TEII; Similar to: HI0076, TESB_HAEIN YP_247740.1 cysteine--tRNA ligase; CysRS; catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_247741.1 PPIase B; rotamase B; Similar to: HI0079, PPIB_HAEIN YP_247742.1 Similar to: HI0080, YIFN_HAEIN YP_247743.1 Similar to: HI0081, YJJV_HAEIN YP_247746.1 TRX; Similar to: HI0084, THIO_HAEIN YP_247747.1 Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthes YP_247748.1 CGS; O-succinylhomoserine (Thiol)-lyase; catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity YP_247750.1 Similar to: HI1574, DNAB_PASMU YP_247756.1 SSB; Helix-destabilizing protein; binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_247759.1 decatenates replicating daughter chromosomes YP_247764.1 Similar to: HI0952 YP_247785.1 Similar to: TNP3_ECOLI YP_247787.2 Similar to: TNR3_ECOLI YP_247797.1 Similar to: TRC4_ECOLI YP_247809.1 Similar to: XERC_PSESX YP_247810.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_247811.1 HK; catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_247812.1 bifunctional protein including aspartokinase, homoserine dehydrogenase; AK-HD; multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_247813.1 Similar to: HI0090, Y090_HAEIN YP_247814.1 Similar to: HI0091, GRK_HAEIN YP_247815.1 Similar to: HI0092, Y092_HAEIN YP_247816.1 Similar to: HI0093, Y093_HAEIN YP_247817.1 Similar to: HI0094, Y094_HAEIN YP_247818.1 Similar to: HI0095, Y095_HAEIN YP_247819.1 Similar to: HI0096, Y096_HAEIN YP_247820.1 Major ferric iron binding protein; Iron-regulated 40 kDa protein; MIRP; Fe(3+)-binding protein; Similar to: HI0097, FBPA_HAEIN YP_247821.1 Similar to: HI0098, FBB2_HAEIN YP_247822.1 Similar to: HI0099, FBC2_HAEIN YP_247823.1 Similar to: HI0100, Y100_HAEIN YP_247824.1 SDAP; dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica YP_247825.1 Similar to: HI0103, YFFB_HAEIN YP_247826.1 Heat shock protein htpG; High temperature protein G; molecular chaperone YP_247827.1 Similar to: HI0105, YBGI_HAEIN YP_247832.1 Fifty-four homolog; Similar to: HI0106, SR54_HAEIN YP_247833.1 Similar to: HI0107, YFJD_HAEIN YP_247834.1 Similar to: HI0108, YJJP_ECOLI YP_247835.1 Similar to: HI0108, YJJP_HAEIN YP_247836.1 Similar to: HI0109, Y109_HAEIN YP_247837.1 Serine--tRNA ligase; SerRS; catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_247838.1 Similar to: HI0111, GT_HAEIN YP_247840.1 Similar to: HI0113, HXC1_HAEIN YP_247841.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_247842.1 murein hydrolase A; Mlt38; membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_247843.1 homolog of dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; Similar to: HI0118, YGDL_HAEIN YP_247844.1 involved in transport of zinc(II) with ZnuA and C YP_247845.1 Similar to: HI0120, Y120_HAEIN YP_247846.1 Murein peptide ligase; Similar to: HI0121, MPL_HAEIN YP_247847.1 CBL; beta-cystathionase; cysteine lyase; catalyzes the formation of L-homocysteine from cystathionine YP_247848.1 Similar to: TSAA_BUCAP YP_247849.1 phosphatidylglycerophosphate synthase; PGP synthase; Similar to: HI0123, PGSA_HAEIN YP_247850.1 pyrophosphate phospho-hydrolase; PPase; catalyzes the hydrolysis of pyrophosphate to phosphate YP_247851.1 Similar to: HI0125, YJCD_HAEIN YP_247852.1 uridine monophosphokinase; cytidine monophosphokinase; functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_247853.1 dCTP deaminase; Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_247854.1 Similar to: HI0134, Y134_HAEIN YP_247855.1 Similar to: HI0135, SOTB_HAEIN YP_247856.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_247857.1 3'-5' exonuclease of DNA polymerase III YP_247858.1 RNase HI; An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_247859.1 OMP P2; Similar to: HI0139, OP27_HAEIN YP_247860.1 GlcNAc 6-P deacetylase; catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_247861.1 glucosamine-6-phosphate isomerase; GNPDA; GlcN6P deaminase; catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_247862.1 N-acetylneuraminic acid aldolase; N-acetylneuraminate pyruvate-lyase; sialic acid lyase; sialate lyase; sialic acid aldolase; catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid YP_247863.1 Similar to: HI0143, Y143_HAEIN YP_247864.1 ManNAc kinase; catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein YP_247865.1 ManNAc-6-P epimerase; Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_247866.1 Similar to: HI0146, Y146_HAEIN YP_247867.1 Similar to: HI0147, Y147_HAEIN YP_247868.1 Similar to: HI0148, YJHT_HAEIN YP_247869.1 Similar to: HI0149 YP_247870.1 Similar to: HI0150, HFLC_HAEIN YP_247871.1 Similar to: HI0151, HFLK_HAEIN YP_247872.1 Similar to: HI0152, Y152_HAEIN YP_247873.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_247874.1 ACP; carries the fatty acid chain in fatty acid biosynthesis YP_247875.1 3-ketoacyl-acyl carrier protein reductase; catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_247876.1 MCT; Similar to: HI0156, FABD_HAEIN YP_247877.1 beta-ketoacyl-ACP synthase III; KAS III; FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_247878.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_247879.1 Similar to: HI0159, YCED_HAEIN YP_247880.1 phosphatidylserine decarboxylase alpha chain; phosphatidylserine decarboxylase beta chain; catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_247881.1 GR; GRase; catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_247882.1 Similar to: HI0162, YAJG_HAEIN YP_247883.1 Na(+)-translocating NQR subunit A; Na(+)-NQR subunit A; NQR complex subunit A; NQR-1 subunit A; uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_247884.1 Na(+)-translocating NQR subunit B; Na(+)-NQR subunit B; NQR complex subunit B; NQR-1 subunit B; uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_247885.1 Na(+)-translocating NQR subunit C; Na(+)-NQR subunit C; NQR complex subunit C; NQR-1 subunit C; uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_247886.1 Na(+)-translocating NQR subunit D; Na(+)-NQR subunit D; NQR complex subunit D; NQR-1 subunit D; Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_247887.1 Na(+)-translocating NQR subunit E; Na(+)-NQR subunit E; NQR complex subunit E; NQR-1 subunit E; Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol YP_247888.1 Na(+)-translocating NQR subunit F; Na(+)-NQR subunit F; NQR complex subunit F; NQR-1 subunit F; uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_247889.1 Similar to: HI0172, APBE_HAEIN YP_247890.1 Similar to: HI0173, Y173_HAEIN YP_247891.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_247892.1 Similar to: HI0175, YFIH_HAEIN YP_247893.1 pseudouridylate synthase; Uracil hydrolyase; responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_247894.1 Similar to: HI0177, YFIO_HAEIN YP_247895.1 Similar to: HI0178, Y178_HAEIN YP_247896.1 PFL-activating enzyme; activates pyruvate formate-lyase 1 under anaerobic conditions YP_247897.1 pyruvate formate-lyase; Similar to: HI0180, PFLB_HAEIN YP_247898.1 Similar to: HI0181, FOCA_HAEIN YP_247899.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine YP_247900.1 Similar to: HI0183, YAAJ_HAEIN YP_247901.1 Similar to: HI0184, YAIM_HAEIN YP_247902.1 Similar to: HI0186, Y186_HAEIN YP_247903.1 Similar to: TATA_HAEIN YP_247904.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_247905.1 Similar to: HI0188, TATC_HAEIN YP_247906.1 NADP-GDH; converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_247907.1 ferric uptake regulator; Similar to: HI0190, FUR_HAEIN YP_247908.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_247909.1 Similar to: HI0193, Y193_HAEIN YP_247910.1 negative modulator of the initiation of chromosome replication YP_247911.1 OSB-CoA synthetase; O-succinylbenzoyl-CoA synthetase; Similar to: HI0194, MENE_HAEIN YP_247912.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_247913.1 5-enolpyruvylshikimate-3-phosphate phospholyase; catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_247914.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_247915.1 Similar to: HI0198, YFCA_HAEIN YP_247916.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_247917.1 selenophosphate synthetase; selenium donor protein; catalyzes the formation of selenophosphate from selenide and ATP YP_247918.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_247919.1 M1G-methyltransferase; tRNA [GM37] methyltransferase; methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_247920.1 Essential for efficient processing of 16S rRNA YP_247921.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_247922.1 Similar to: HI0205, Y205_HAEIN YP_247923.1 5'-nucleotidase; Similar to: HI0206, 5NTD_HAEIN YP_247924.1 SK; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_247925.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_247926.1 deoxyadenosyl-methyltransferase; DNA adenine methyltransferase; M.HindIV; Similar to: HI0209, DMA_HAEIN YP_247928.1 Similar to: HI0211, PGPB_HAEIN YP_247929.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_247930.1 Similar to: HI0213, Y213_HAEIN YP_247932.1 Similar to: HI0214, OPDA_HAEIN YP_247933.1 M protein; Similar to: HI1287, T1MP_ECOLI YP_247934.1 S protein; Similar to: HI0216, T1SI_HAEIN YP_247935.1 Similar to: PRRC_ECOLI YP_247937.1 R protein; Similar to: T1R1_ECOLI YP_247938.1 Similar to: HI0219, YKGB_HAEIN YP_247939.1 Similar to: HI1651, ARCB_HAEIN YP_247940.1 Similar to: HI0220.2, Y22A_HAEIN YP_247941.1 Biotin--protein ligase; catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_247942.1 IMP dehydrogenase; IMPDH; IMPD; catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_247943.1 glutamine amidotransferase; GMP synthetase; contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_247944.1 Similar to: HI0223, Y223_HAEIN YP_247945.1 Similar to: HI0224, Y224_HAEIN YP_247946.1 Sodium/proton antiporter 1; exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_247947.1 branched-chain amino acid uptake carrier; Similar to: HI0226, BRNQ_HAEIN YP_247948.1 Similar to: HI0227, YHCH_HAEIN YP_247949.1 Similar to: HI0228, Y228_HAEIN YP_247950.1 polynucleotide phosphorylase; PNPase; Similar to: HI0229, PNP_HAEIN YP_247951.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_247952.1 ATP-dependent RNA helicase DeaD homolog; Similar to: HI0231, DEAD_HAEIN YP_247953.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_247954.1 Similar to: HI0233 YP_247955.1 Similar to: HI0234 YP_247956.1 Similar to: HI0235, YHDL_HAEIN YP_247957.1 Similar to: HI0236, ARSC_HAEIN YP_247958.1 Similar to: PERM_HAEIN YP_247959.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_247960.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_247961.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_247962.1 Similar to: HI0242, Y242_HAEIN YP_247963.1 Similar to: HI0243, Y243_HAEIN YP_247964.1 tRNA-guanine transglycosylase; guanine insertion enzyme; Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_247965.1 queuosine biosynthesis protein QueA; Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_247966.1 Similar to: HI0246, Y246_HAEIN YP_247967.1 Similar to: HI0990, HAP_HAEIN YP_247968.1 UvrA; excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_247969.1 SSB; Helix-destabilizing protein; binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_247970.1 Similar to: HI0251, TONB_HAEIN YP_247971.1 Similar to: HI0252, EXBD_HAEIN YP_247972.1 Similar to: HI0253, EXBB_HAEIN YP_247973.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_247974.1 DHDPS; catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_247975.1 Similar to: HI0256, Y256_HAEIN YP_247976.1 Similar to: HI0257, YFIA_HAEIN YP_247977.1 Similar to: HI0258, Y258_HAEIN YP_247978.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_247979.1 KDO kinase; catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position YP_247980.1 Similar to: HI0261, Y261_HAEIN YP_247981.1 heme:hemopexin utilization protein C; Similar to: HI0262, HXC2_HAEIN YP_247982.1 heme:hemopexin utilization protein B; Similar to: HI0263, HXB2_HAEIN YP_247983.1 heme:hemopexin utilization protein A; Similar to: HI0264, HXA2_HAEIN YP_247984.1 DHNA; Similar to: HI0265, FOLB_HAEIN YP_247985.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_247986.1 Similar to: HI0267, NARQ_HAEIN YP_247987.1 UDP-N-acetylmuramate dehydrogenase; catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_247988.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_247989.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_247990.1 OPRT; OPRTase; involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_247991.1 RNase PH; tRNA nucleotidyltransferase; RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_247992.1 glutamate--tRNA ligase; GluRS; Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_247993.1 Similar to: HI0275, Y275_HAEIN YP_247994.1 RNase BN; RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_247995.1 Similar to: HI0277, Y277_HAEIN YP_247996.1 Similar to: HI0278, YIIM_HAEIN YP_247997.2 UrdPase; UPase; catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_247998.1 Similar to: HI0281, Y281_HAEIN YP_247999.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_248000.1 SHCHC synthase; alpha-ketoglutarate decarboxylase; KDC; SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_248001.1 isochorismate mutase; synthesizes isochorismate acid from chorismate YP_248002.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_248003.1 tryptophan permease; Similar to: HI0287, MTR_HAEIN YP_248004.1 L-serine deaminase; SDH; L-SD; Similar to: HI0288, SDHL_HAEIN YP_248005.1 Similar to: HI0289, SDAC_HAEIN YP_248006.1 Similar to: HI0290, Y290_HAEIN YP_248007.1 Similar to: HI0293, Y293_HAEIN YP_248008.1 Met regulon regulatory protein metJ; when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_248009.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_248010.1 Similar to: HI0296, LEP4_HAEIN YP_248011.1 Similar to: HI0297, HOFC_HAEIN YP_248012.1 Similar to: HI0298, HOFB_HAEIN YP_248013.1 Similar to: HI0299, PPDD_HAEIN YP_248014.1 Similar to: HI0300, AMPD_HAEIN YP_248015.1 Similar to: HI0301, CORC_HAEIN YP_248016.1 ALP N-acyltransferase; Copper homeostasis protein CutE homolog; Transfers the fatty acyl group on membrane lipoproteins YP_248017.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_248018.1 Similar to: HI0304, YQGE_HAEIN YP_248019.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_248020.1 Similar to: INTA_ECOLI YP_248027.1 P5CR; P5C reductase; catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_248028.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_248029.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_248030.1 Similar to: HI0310, Y310_HAEIN YP_248031.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_248032.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_248033.1 holliday junction nuclease RuvC; holliday juction resolvase RuvC; endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_248034.1 Similar to: HI0315, Y315_HAEIN YP_248035.1 converts dATP to dAMP and pyrophosphate YP_248036.1 aspartate--tRNA ligase; AspRS; catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_248037.1 Similar to: HI0318, Y318_HAEIN YP_248038.1 fold typical of S-adenosyl-L-methionine-dependent methyltransferases; Similar to: HI0319, YECO_HAEIN YP_248039.1 Similar to: HI0321, Y321_HAEIN YP_248040.1 Similar to: HI0322, Y322_HAEIN YP_248041.1 methylglyoxalase; aldoketomutase; glyoxalase I; Glx I; Ketone-aldehyde mutase; S-D-lactoylglutathione methylglyoxal lyase; Similar to: HI0323, LGUL_HAEIN YP_248042.1 exoribonuclease T; RNase T; Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_248043.1 Similar to: HI0325, Y325_HAEIN YP_248044.1 Similar to: HI0326, Y326_HAEIN YP_248045.1 EF-P; Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_248046.1 Similar to: HI0329, YJEK_HAEIN YP_248047.1 Similar to: HI0330, OAPA_HAEIN YP_248048.1 Similar to: HI0331, OAPB_HAEIN YP_248049.1 recombination protein O; involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_248050.1 23S rRNA(M-5-U1939)-methyltransferase; in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_248051.1 ATP:GTP 3'-pyrophosphotransferase; ppGpp synthetase I; (P)ppGpp synthetase; Similar to: HI0334, RELA_HAEIN YP_248052.1 DAGK; diglyceride kinase; DGK; Similar to: HI0335, KDGL_HAEIN YP_248053.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_248054.1 Similar to: HI0337, GLNB_HAEIN YP_248055.1 Similar to: HI0338, YHHT_HAEIN YP_248056.1 replication factor Y; binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_248057.1 tRNA(m7G46)-methyltransferase; tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_248058.1 Similar to: HI0341, YGGL_HAEIN YP_248059.1 Similar to: HI0342, NAPF_HAEIN YP_248060.1 Similar to: HI0343, NAPD_HAEIN YP_248061.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_248062.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_248063.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_248064.1 Similar to: HI0347, NAPB_HAEIN YP_248065.1 Similar to: HI0348, NAPC_HAEIN YP_248066.1 ATP-AMP transphosphorylase; essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_248067.1 Similar to: HI0350, Y350_HAEIN YP_248068.1 galactowaldenase; UDP-galactose 4-epimerase; Similar to: HI0351, GALE_HAEIN YP_248069.1 Similar to: HI0352, Y352_HAEIN YP_248070.1 Similar to: HI0354, Y354_HAEIN YP_248071.1 Similar to: HI0355, Y355_HAEIN YP_248072.1 Similar to: HI0357, Y357_HAEIN YP_248073.1 Similar to: HI0358, Y358_HAEIN YP_248074.1 Similar to: HI0359, Y359_HAEIN YP_248075.1 Similar to: HI0360, Y360_HAEIN YP_248076.1 Similar to: HI0361, Y361_HAEIN YP_248077.1 Similar to: HI0362, Y362_HAEIN YP_248079.1 PBP-7; D-alanyl-D-alanine-endopeptidase; DD-endopeptidase; Similar to: HI0364, PBP7_HAEIN YP_248080.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_248081.1 Similar to: HI0366, Y366_HAEIN YP_248082.1 Similar to: HI0367, Y367_HAEIN YP_248083.1 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_248084.1 histidine--tRNA ligase; HisRS; catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_248085.1 Similar to: HI0370, Y370_HAEIN YP_248086.1 Similar to: HI0371, YFHJ_HAEIN YP_248087.1 Similar to: HI0372, FER_HAEIN YP_248088.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_248089.1 Similar to: HI0374, YBFG_HAEIN YP_248090.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_248091.1 Similar to: HI0376, YFHF_HAEIN YP_248092.1 Similar to: HI0377, NIFU_HAEIN YP_248093.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_248094.1 Similar to: HI0379, YFHP_HAEIN YP_248095.1 Similar to: HI0380, YFHQ_HAEIN YP_248096.1 OMP P6; 15 kDa peptidoglycan-associated lipoprotein; PC protein; Similar to: HI0381, PAL_HAEIN YP_248097.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_248098.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_248099.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_248100.1 Similar to: HI0385, TOLQ_HAEIN YP_248101.1 Similar to: HI0386, YBGC_HAEIN YP_248102.1 Similar to: HI0387, YOAA_HAEIN YP_248103.1 Similar to: HI0388, YEAZ_HAEIN YP_248104.1 Similar to: HI0389, Y389_HAEIN YP_248105.1 long-chain acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A YP_248106.1 RNase D; Similar to: HI0390, RND_HAEIN YP_248107.1 Similar to: HI0392, Y392_HAEIN YP_248108.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_248109.1 PTH; Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_248110.1 Similar to: HI0395, YFJF_HAEIN YP_248111.1 Similar to: HI0396, YCFD_HAEIN YP_248112.1 exonuclease VII large subunit; bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_248113.1 ADP-ribose diphosphatase; adenosine diphosphoribose pyrophosphatase; ADPR-PPase; ADP-ribose phosphohydrolase; Similar to: HI0398, ADPP_HAEIN YP_248114.1 Similar to: HI0399, ICC_HAEIN YP_248115.1 Similar to: HI0400, Y400_HAEIN YP_248116.1 OMP P1; Similar to: HI0401, OM12_HAEIN YP_248117.1 6-O-methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase; Similar to: HI0402, OGT_HAEIN YP_248118.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_248119.1 Similar to: HI0404, MESJ_HAEIN YP_248120.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_248121.1 Similar to: HI0407, ZNUB_HAEIN YP_248122.1 Similar to: HI0408, ZNUC_HAEIN YP_248123.1 Similar to: HI0409, Y409_HAEIN YP_248124.1 Similar to: HI0410, TYRR_HAEIN YP_248125.1 Stimulates the elongation of poly(A) tails YP_248126.1 pseudouridylate synthase; Uracil hydrolyase; catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_248127.1 RNase E; Similar to: HI0413, RNE_HAEIN YP_248128.1 Similar to: HI0414, Y414_HAEIN YP_248129.1 4-methyl-5-beta-hydroxyethylthiazole kinase; Thz kinase; TH kinase; catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_248130.1 HMP-phosphate kinase; HMP-P kinase; catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_248131.1 TMP pyrophosphorylase; TMP-PPase; thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_248132.1 Similar to: HI0418, Y418_HAEIN YP_248134.1 Similar to: HI0419, YEGQ_HAEIN YP_248135.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_248136.1 Similar to: HI0423, YFIC_HAEIN YP_248137.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_248138.1 Multifunctional regulator of fatty acid metabolism YP_248139.1 Sodium/proton antiporter 2; involved in regulation of intracellular pH under alkaline conditions YP_248140.1 disulfide oxidoreductase; disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_248141.1 hexosephosphate aminotransferase; D-fructose-6-phosphate amidotransferase; GFAT; L-glutamine-D-fructose-6-phosphate amidotransferase; glucosamine-6-phosphate synthase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_248142.1 Similar to: HI0430, DBH_HAEIN YP_248143.1 Similar to: HI0431, YJAG_HAEIN YP_248144.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_248145.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_248146.1 DNA transformation protein comF; protein COM101A; Similar to: HI0434, COMF_HAEIN YP_248147.1 DNA transformation protein comE; Similar to: HI0435, COME_HAEIN YP_248148.1 DNA transformation protein comD; Similar to: HI0436, COMD_HAEIN YP_248149.1 DNA transformation protein comC; Similar to: HI0437, COMC_HAEIN YP_248150.1 DNA transformation protein comB; Similar to: HI0438, COMB_HAEIN YP_248151.1 DNA transformation protein comA; Similar to: HI0439, COMA_HAEIN YP_248152.1 PBP-1a; PBP1a; penicillin-binding protein A; peptidoglycan TGase; DD-transpeptidase; Similar to: HI0440, PBPA_HAEIN YP_248153.1 Similar to: HI0441, YHIR_HAEIN YP_248154.1 Similar to: HI0442, Y442_HAEIN YP_248155.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_248156.1 decatenates replicating daughter chromosomes YP_248157.1 Similar to: HI0445, SECG_HAEIN YP_248158.1 EIIBC-Fru; fructose-permease IIBC component; phosphotransferase enzyme II, BC component; EII-Fru; Similar to: HI0446, PTFB_HAEIN YP_248159.1 fructose 1-phosphate kinase; converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_248160.1 EIIA-Fru; fructose-permease IIA/FPr component; phosphotransferase enzyme II, A/FPr component; phosphotransferase FPr protein; Pseudo-HPr; EIII-Fru; fructose PTS diphosphoryl transfer protein; phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_248161.1 Similar to: HI0449, Y449_HAEIN YP_248162.1 Similar to: HI0450, VAPD_HAEIN YP_248163.1 Similar to: HI0451, Y451_HAEIN YP_248164.1 Similar to: HI0452, YTFL_HAEIN YP_248165.1 Similar to: HI0453, Y453_HAEIN YP_248166.1 Similar to: HI0454, YCFH_HAEIN YP_248167.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_248169.1 Similar to: YDEU_ECOLI YP_248170.1 dTMP kinase; catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_248171.1 Similar to: HI0457, YCEG_HAEIN YP_248172.1 Similar to: HI0458, SURA_HAEIN YP_248173.1 UPRTase; regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_248174.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_248175.1 Similar to: HI0461, Y461_HAEIN YP_248176.1 Lon protease; Similar to: HI0462, LON_HAEIN YP_248177.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_248178.1 phosphoriboisomerase A; PRI; Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_248179.1 PGDH; catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_248180.1 Similar to: HI0466, Y466_HAEIN YP_248181.1 Similar to: HI0467, YICC_HAEIN YP_248182.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_248183.1 HDH; catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_248184.1 imidazole acetol-phosphate transaminase 1; catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_248185.1 IGPD; catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_248186.1 IGP synthase glutamine amidotransferase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_248187.1 5-phosphoribosyl; 5-phosphoribosylamino; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_248188.1 IGP synthase cyclase subunit; IGP synthase subunit HisF; ImGP synthase subunit HisF; IGPS subunit HisF; catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_248189.1 PRA-CH; PRA-PH; catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_248191.1 TyrP-A; tyrosine permease 1; Similar to: HI0477, TYRP_HAEIN YP_248192.1 ATP synthase F1 sector epsilon subunit; part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_248193.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_248194.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_248195.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_248196.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_248197.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_248198.1 Lipid-binding protein; dicyclohexylcarbodiimide-binding protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_248199.1 protein 6; Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_248200.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_248201.1 glucose inhibited division protein B; glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_248202.1 Similar to: HI0487, YHFY_HAEIN YP_248203.1 Similar to: HI0488, YQAB_HAEIN YP_248204.1 Similar to: HI0489, YQAA_HAEIN YP_248205.1 autoinducer-2 production protein LuxS; AI-2 synthesis protein; catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_248206.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity YP_248207.1 heat shock protein involved in degradation of misfolded proteins YP_248208.1 heat shock protein involved in degradation of misfolded proteins YP_248209.1 SPBP; Similar to: HI0498, POT2_HAEIN YP_248210.1 Similar to: HI0499, ORDL_HAEIN YP_248211.1 Similar to: HI0500, RMUC_HAEIN YP_248212.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_248213.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_248214.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_248215.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_248216.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_248217.1 Similar to: HI0506, RBSR_HAEIN YP_248218.1 Similar to: HI0507, YQHA_HAEIN YP_248219.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_248220.1 DHNA-octaprenyltransferase; catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_248221.1 Similar to: HI0510, YAEB_HAEIN YP_248222.1 Similar to: HI0511, TEHA_HAEIN YP_248223.1 transcriptase beta' chain; RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_248224.1 transcriptase beta chain; RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_248225.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_248226.1 binds directly to 23S ribosomal RNA YP_248227.1 inosine phosphorylase; PNP; catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_248228.1 Similar to: HI0519, YEIM_HAEIN YP_248229.1 Similar to: HI0520, Y520_HAEIN YP_248230.1 Similar to: HI0521, YJJI_HAEIN YP_248231.1 Similar to: HI0522, Y522_HAEIN YP_248232.1 Similar to: HI0523, Y523_HAEIN YP_248233.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_248234.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_248235.1 Similar to: HI0526, RN26_HAEIN YP_248236.1 Similar to: HI0527, YFHL_HAEIN YP_248237.1 TyrP-B; tyrosine permease 2; Similar to: HI0528, TYRQ_HAEIN YP_248238.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_248239.1 glycoprotease; in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_248240.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_248241.1 synthesizes RNA primers at the replication forks YP_248242.1 Sigma-70; Similar to: HI0533, RPSD_HAEIN YP_248243.1 aspartase; catalyzes the formation of fumarate from aspartate YP_248244.1 Similar to: HI0535, UREH_HAEIN YP_248245.1 Similar to: HI0536, UREG_HAEIN YP_248246.1 Similar to: HI0537, UREF_HAEIN YP_248247.1 involved in the assembly of the urease metallocenter; possible nickel donor YP_248248.1 Urea amidohydrolase; ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_248249.1 Urea amidohydrolase; ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active YP_248250.1 Urea amidohydrolase gamma subunit; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_248251.1 Cpn10; groES; 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_248252.1 Cpn60; groEL; 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_248253.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_248254.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_248255.1 binds single-stranded DNA at the primosome assembly site YP_248256.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_248257.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_248258.1 S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase; 16S rRNA dimethylase; High level kasugamycin resistance protein ksgA; kasugamycin dimethyltransferase; catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_248259.1 Similar to: HI0550, LEX1_HAEIN YP_248260.1 5'-nucleosyl; diadenosine tetraphosphatase; Ap4A hydrolase; diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_248261.1 Similar to: HI0552, Y552_HAEIN YP_248262.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_248263.1 Similar to: HI0554, Y554_HAEIN YP_248265.2 6PGL; catalyzes the formation of 6-phospho-D-gluconate from 6-phospho-D-glucono-1,5-lactone YP_248266.1 G6PD; catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_248267.1 Similar to: HI0559, CYSQ_HAEIN YP_248268.1 Similar to: HI0559.1, Y55A_HAEIN YP_248269.1 Similar to: HI0561, Y561_HAEIN YP_248270.1 HSP15; Similar to: HI0562, HSLR_HAEIN YP_248271.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_248272.1 asparagine synthetase A; catalyzes the formation of asparagine from aspartate and ammonia YP_248273.1 Similar to: HI1721, YH21_HAEIN YP_248277.1 PGP; catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_248278.1 pentose-5-phosphate 3-epimerase; PPE; R5P3E; catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_248279.1 negatively supercoils closed circular double-stranded DNA YP_248280.1 Similar to: HI0568, YHGF_HAEIN YP_248281.1 transcript cleavage factor greB; necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_248282.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_248283.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_248284.1 Similar to: HI0572, Y572_HAEIN YP_248285.1 Similar to: HI0573, SLYX_HAEIN YP_248286.1 PPIase; rotamase; Similar to: HI0574, FKBY_HAEIN YP_248287.1 Similar to: HI0575, YHEO_HAEIN YP_248288.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_248289.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_248290.1 Similar to: HI0577, Y577_HAEIN YP_248291.1 EF-Tu; EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_248292.1 pantothenic acid kinase; catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_248293.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_248294.1 Similar to: HI0629, RSEA_HAEIN YP_248295.1 Sigma-24; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_248296.1 Similar to: HI0627, YGFY_HAEIN YP_248297.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_248298.1 K(+)-uptake protein trkA; involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_248299.1 FMU protein; predicted tRNA or rRNA cytosine-C5-methylase; Similar to: HI0624, SUN_HAEIN YP_248300.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_248301.1 PDF; polypeptide deformylase; cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_248304.1 competence activator; protein sxy; Similar to: HI0601, TFOX_HAEIN YP_248305.1 recombinase A; recombinase 1; catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_248306.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_248307.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_248308.1 Similar to: HI0597, YIGL_HAEIN YP_248309.1 OTCase; Similar to: HI0596, OTCC_HAEIN YP_248310.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_248311.1 Similar to: HI0594, YFCC_HAEIN YP_248312.1 alpha-aspartyl dipeptidase; Asp-specific dipeptidase; dipeptidase E; alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_248313.1 Similar to: HI0585, Y585_HAEIN YP_248314.1 Similar to: HI0584, ABGA_HAEIN YP_248315.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_248318.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_248319.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_248320.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_248321.1 EF-G; EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_248322.1 EF-Tu; EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_248324.1 Similar to: HI0633 YP_248325.1 Similar to: HI0634, DUSA_HAEIN YP_248326.1 Similar to: HI0636, Y636_HAEIN YP_248327.1 tryptophan--tRNA ligase; TrpRS; catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_248328.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_248329.1 adenylosuccinase; ASL; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_248330.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_248331.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_248332.1 N-acetylglucosamine-1-phosphate uridyltransferase; forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_248334.1 lecithinase B; Similar to: HI0645, PLDB_HAEIN YP_248335.1 ASA dehydrogenase; ASADH; catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_248336.1 Similar to: HI0647, Y647_HAEIN YP_248337.1 Similar to: HI0019, YF71_PASMU YP_248338.1 Similar to: HI0648, MDAB_HAEIN YP_248339.1 Similar to: HI0649, REP_HAEIN YP_248340.1 Similar to: HI0650, Y650_HAEIN YP_248341.1 pantetheine-phosphate adenylyltransferase; PPAT; dephospho-CoA pyrophosphorylase; Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_248342.1 KDO transferase; catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_248343.1 Similar to: HI0653, Y653_HAEIN YP_248344.1 3-methyladenine-DNA glycosidase; TAG; Similar to: HI0654, 3MGA_HAEIN YP_248346.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_248347.1 Similar to: HI0656, YRDC_HAEIN YP_248348.1 Similar to: HI0656.1, YRDD_HAEIN YP_248349.1 Similar to: HI0658, YHES_HAEIN YP_248350.1 Similar to: HI0659, Y659_HAEIN YP_248351.1 Similar to: HI0660 YP_248352.1 hemoglobin-haptoglobin utilization protein B; Similar to: HI0661, HGPB_HAEIN YP_248353.1 Similar to: HI0663, Y663_HAEIN YP_248354.1 Similar to: HI0664, Y664_HAEIN YP_248355.1 Similar to: HI0665, Y665_HAEIN YP_248356.1 Similar to: HI0666, Y666_HAEIN YP_248357.1 Similar to: HI0666.1, Y66A_HAEIN YP_248358.1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class II glpX; FBPase II glpX; type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_248359.1 Similar to: HI0668 YP_248360.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_248361.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_248362.1 MECPS; MECDP-synthase; catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_248363.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_248364.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_248365.1 XGPRT; catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_248366.1 Xaa-His dipeptidase; X-His dipeptidase; beta-alanyl-histidine dipeptidase; carnosinase; peptidase D; Similar to: HI0675, PEPD_HAEIN YP_248367.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_248368.1 Similar to: HI0677, Y677_HAEIN YP_248369.1 TIM; Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_248370.1 Similar to: HI0679, GLPE_HAEIN YP_248371.1 Similar to: HI0680, Y680_HAEIN YP_248372.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_248373.1 acetohydroxy-acid isomeroreductase; alpha-keto-beta-hydroxylacil reductoisomerase; catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_248374.1 G-3-P dehydrogenase; anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_248375.1 G-3-P dehydrogenase; sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_248376.1 G-3-P dehydrogenase; anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_248377.1 G-3-P transporter; G-3-P permease; Similar to: HI0686, GLPT_HAEIN YP_248378.1 glycerophosphodiester phosphodiesterase; surface-exposed lipoprotein D; hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_248379.1 Similar to: HI0690, GLPF_HAEIN YP_248380.1 ATP:glycerol 3-phosphotransferase; glycerokinase; GK; Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_248381.1 XGPRT; catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_248382.1 lipoprotein E; OMP P4; Similar to: HI0693, HEL_HAEIN YP_248383.1 pseudouridylate synthase; Uracil hydrolyase; Similar to: HI0694, RLUE_HAEIN YP_248384.1 Similar to: HI0696, YTFN_HAEIN YP_248385.1 Similar to: HI0698, YTFM_HAEIN YP_248386.1 PPIase; rotamase; Similar to: HI0699, SLYD_HAEIN YP_248387.1 Similar to: HI0700, YJGD_HAEIN YP_248388.1 pseudouridylate synthase; Uracil hydrolyase; catalyzes the modification of U13 in tRNA(Glu) YP_248389.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_248390.1 Similar to: HI0703, Y703_HAEIN YP_248391.1 Similar to: HI0704, Y704_HAEIN YP_248392.1 Similar to: HI0706, LPPB_HAEIN YP_248393.1 L-tryptophan indole-lyase; TNase; tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan YP_248394.1 tryptophan permease; Similar to: HI0287, MTR_HAEIN YP_248395.1 This protein performs the mismatch recognition step during the DNA repair process YP_248396.1 Sec; cysteinyl-tRNA(Sec) selenium transferase; selenocysteine synthase; selenocysteinyl-tRNA(Sec) synthase; catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_248397.1 SelB translation factor; Similar to: HI0709, SELB_HAEIN YP_248399.1 Similar to: HI0710, Y710_HAEIN YP_248400.1 Similar to: HI0711, YAFQ_HAEIN YP_248401.1 TF; Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_248402.1 endopeptidase Clp; hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_248403.1 binds and unfolds substrates as part of the ClpXP protease YP_248404.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_248405.1 Modulates Rho-dependent transcription termination YP_248406.1 Similar to: HI0718, VACJ_HAEIN YP_248407.1 Similar to: HI0719, YJGF_HAEIN YP_248408.1 metalloprotease YP_248409.2 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_248410.1 Similar to: HI0722, YIGZ_HAEIN YP_248411.1 Similar to: HI0723, TRKH_HAEIN YP_248413.1 Similar to: HI0602, HEMY_HAEIN YP_248414.1 Similar to: HI0603, Y603_HAEIN YP_248415.1 ATP pyrophosphate-lyase; adenylyl cyclase; catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_248416.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_248417.1 SAT; catalyzes the O-acetylation of serine YP_248418.1 catalyzes the conversion of shikimate to 3-dehydroshikimate YP_248419.1 Similar to: HI0608, Y608_HAEIN YP_248420.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_248421.1 Similar to: HI0610, FUCP_HAEIN YP_248422.1 L-fuculose-1-phosphate aldolase; catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_248423.1 Similar to: HI0612, FUCU_HAEIN YP_248424.1 L-fuculose kinase; Similar to: HI0613, FUCK_HAEIN YP_248425.2 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose YP_248426.1 Similar to: HI0615, FUCR_HAEIN YP_248427.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_248428.1 pseudouridylate synthase; uracil hydrolyase; Similar to: HI0617, RLUA_HAEIN YP_248429.1 Similar to: HI0618, GLPG_HAEIN YP_248430.1 Similar to: HI0619, GLPR_HAEIN YP_248431.1 Similar to: HI0620, METQ_HAEIN YP_248432.1 Similar to: METI_HAEIN YP_248433.1 part of the metNIQ transport system for methionine YP_248434.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_248435.1 Similar to: HI0724, Y724_HAEIN YP_248436.1 Similar to: HI0725, Y725_HAEIN YP_248437.1 Similar to: HI0726, NARP_HAEIN YP_248438.1 DAP decarboxylase; Similar to: HI0727, DCDA_HAEIN YP_248440.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_248441.1 Similar to: HI0728, RECQ_HAEIN YP_248442.1 proline--tRNA ligase; ProRS; catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_248443.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_248444.1 Similar to: HI0733, SUFI_HAEIN YP_248445.1 1-AGP acyltransferase; 1-AGPAT; lysophosphatidic acid acyltransferase; LPAAT; Similar to: HI0734, PLSC_HAEIN YP_248446.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_248447.1 Similar to: HI0736, Y736_HAEIN YP_248448.1 Similar to: HI0737, Y737_HAEIN YP_248449.1 DAD; catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_248450.1 threonine deaminase; threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_248451.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_248452.1 Similar to: HI0740, Y740_HAEIN YP_248453.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_248454.1 Similar to: HI0744, YIBN_HAEIN YP_248455.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_248456.1 Similar to: HI0747, DHNA_HAEIN YP_248457.1 GPAT; PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_248458.1 Represses a number of genes involved in the response to DNA damage YP_248459.1 DAP epimerase; involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_248460.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_248461.1 FGAM synthase; formylglycinamide ribotide amidotransferase; FGARAT; catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_248463.1 Similar to: HI0755, YIBQ_HAEIN YP_248464.1 Similar to: HI0756, YIBP_HAEIN YP_248465.1 phosphoglyceromutase; PGAM; BPG-dependent PGAM; dPGM; 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_248466.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_248467.1 Similar to: HI0759, MUTY_HAEIN YP_248468.1 Similar to: HI0760, Y760_HAEIN YP_248469.1 Murein hydrolase C; Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_248470.1 Similar to: HI0762, Y762_HAEIN YP_248471.1 NMN adenylyltransferase; ribosylnicotinamide kinase; NMNAT; RNK; catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_248472.1 DHBP synthase; DHBP synthase; functions during riboflavin biosynthesis YP_248473.1 Similar to: HI0765, Y765_HAEIN YP_248474.1 Similar to: HI0766, YIBK_HAEIN YP_248475.1 Similar to: HI0767, YHHF_HAEIN YP_248476.1 Similar to: HI0768, FTSY_HAEIN YP_248477.1 Similar to: HI0769, FTSE_HAEIN YP_248478.1 ABC transporter, membrane protein YP_248479.1 acetoacetyl-CoA thiolase; Similar to: HI0771, ATOB_HAEIN YP_248480.1 Similar to: HI0772, ATOE_HAEIN YP_248481.1 Acetyl-CoA:acetoacetate CoA transferase beta subunit; Similar to: HI0773, ATOA_HAEIN YP_248482.1 Acetyl-CoA:acetoacetate CoA transferase alpha subunit; Similar to: HI0774, ATOD_HAEIN YP_248483.1 Similar to: HI0775, Y775_HAEIN YP_248484.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_248485.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_248486.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_248487.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_248488.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_248489.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_248490.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_248491.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_248492.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_248493.1 one of the stabilizing components for the large ribosomal subunit YP_248494.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_248495.1 Similar to: HI0787, Y787_HAEIN YP_248496.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_248497.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_248498.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_248499.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_248500.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_248501.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_248502.1 binds 5S rRNA along with protein L5 and L25 YP_248503.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_248504.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_248505.1 late assembly protein YP_248506.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_248507.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_248508.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_248509.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_248510.1 RNAP alpha subunit; transcriptase alpha chain; RNA polymerase alpha subunit; catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_248511.1 is a component of the macrolide binding site in the peptidyl transferase center YP_248512.1 Similar to: HI0804, Y804_HAEIN YP_248513.1 Similar to: HI0806, Y806_HAEIN YP_248514.1 DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_248515.1 ribosome releasing factor; RRF; Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_248516.1 PEP carboxykinase; phosphoenolpyruvate carboxylase; PEPCK; PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_248517.1 Heat shock protein 33 homolog; HSP33; becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_248518.1 arginosuccinase; ASAL; catalyzes the formation of arginine from (N-L-arginino)succinate YP_248519.1 UDP-glucose pyrophosphorylase; UDPGP; Alpha-D-glucosyl-1-phosphate uridylyltransferase; uridine diphosphoglucose pyrophosphorylase; Similar to: HI0812, GALU_HAEIN YP_248520.1 affects carbohydrate metabolism; has regulatory role in many processes YP_248521.1 alanine--tRNA ligase; AlaRS; Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_248522.1 Similar to: HI0815, USPA_HAEIN YP_248523.1 X-Pro aminopeptidase; aminopeptidase P II; APP-II; aminoacylproline aminopeptidase; Similar to: HI0816, AMPP_HAEIN YP_248524.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_248525.1 mutarotase; catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose YP_248526.1 galactose kinase; catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_248527.1 Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase; catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_248528.1 galactose operon repressor; Similar to: HI0821, GALR_HAEIN YP_248529.1 GBP; D-galactose/ D-glucose binding protein; GGBP; Similar to: HI0822, DGAL_HAEIN YP_248530.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_248531.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_248532.1 Similar to: HI0825, Y825_HAEIN YP_248533.1 Involved in cell division; probably involved in intracellular septation YP_248534.1 Similar to: HI0827, YCIA_HAEIN YP_248535.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_248536.1 Similar to: HI0829, SLT_HAEIN YP_248537.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_248538.2 monofunctional TGase; glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_248539.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_248540.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_248541.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_248542.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_248543.2 Lysine--tRNA ligase; LysRS; GX; lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_248544.1 Similar to: HI0837, CPXR_HAEIN YP_248545.1 Similar to: HI0838, SMPA_HAEIN YP_248546.1 Similar to: HI0839, NDPA_HAEIN YP_248547.1 Similar to: HI0840, YEJL_HAEIN YP_248548.1 Similar to: HI0841, YEJM_HAEIN YP_248549.1 Similar to: HI0842, Y842_HAEIN YP_248550.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_248551.1 Similar to: HI0845, YIHD_HAEIN YP_248552.1 Similar to: HI0846, DSBA_HAEIN YP_248553.1 Similar to: HI0847, YIFE_HAEIN YP_248554.1 tRNA(M-5-U54)-methyltransferase; RUMT; catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_248555.1 Similar to: HI0849, YHIQ_HAEIN YP_248556.1 Similar to: HI0850, Y850_HAEIN YP_248557.1 Similar to: HI0851, MOBB_HAEIN YP_248558.1 Similar to: HI0852, YIEO_HAEIN YP_248559.1 hemin-binding lipoprotein; Similar to: HI0853, HBPA_HAEIN YP_248560.1 Similar to: HI0854, Y854_HAEIN YP_248561.1 Similar to: HI0855, YHAM_HAEIN YP_248562.1 POL I; has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_248563.1 Similar to: HI0857, YGFE_HAEIN YP_248564.1 Similar to: HI0858, YGFA_HAEIN YP_248565.1 Similar to: HI0859, CLPB_HAEIN YP_248566.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_248567.1 RNase R; VacB; Similar to: HI0861, RNR_HAEIN YP_248568.1 Similar to: HI0862, YHHQ_HAEIN YP_248569.2 PNP/PMP oxidase; PNPOx; catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_248570.1 Similar to: HI0864, TYPA_HAEIN YP_248571.1 Similar to: HI0352, Y352_HAEIN YP_248572.1 glutamate--ammonia ligase; Similar to: HI0865, GLNA_HAEIN YP_248573.1 Similar to: HI0873, RFBB_NEIMB YP_248574.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_248575.1 NDK; NDP kinase; nucleoside-2-P kinase; catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_248576.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_248577.1 Similar to: HI0878, YHBE_HAEIN YP_248578.1 involved in the peptidyltransferase reaction during translation YP_248579.1 Similar to: HI0880, RL21_HAEIN YP_248580.1 octaprenyl pyrophosphate synthetase; OPP synthetase; Similar to: HI0881, ISPB_HAEIN YP_248581.1 Similar to: HI0882, Y882_HAEIN YP_248582.1 Similar to: HI0883, Y883_HAEIN YP_248583.1 Similar to: HI0884, ARCA_HAEIN YP_248584.1 protein-disulfide reductase; disulfide reductase; C-type cytochrome biogenesis protein CycZ; two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_248585.1 Similar to: HI0886, Y886_HAEIN YP_248586.1 AICAR transformylase; inosinicase; IMP synthetase; ATIC; involved in de novo purine biosynthesis YP_248587.1 GARS; glycinamide ribonucleotide synthetase; phosphoribosylglycinamide synthetase; catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_248588.1 Serine methylase; SHMT; catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_248589.1 dephosphocoenzyme A kinase; catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_248590.1 Similar to: HI0891, Y891_HAEIN YP_248591.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_248592.1 Similar to: HI0893, Y893_HAEIN YP_248593.1 Similar to: HI0894, Y894_HAEIN YP_248594.1 Similar to: HI0895, Y895_HAEIN YP_248595.1 Similar to: HI0896, Y896_HAEIN YP_248596.1 Similar to: HI0897, EMRB_HAEIN YP_248597.1 Similar to: HI0898, EMRA_HAEIN YP_248598.1 Similar to: HI0899, DYR_HAEIN YP_248599.1 Gamma-glutamyl kinase; GK; catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_248600.1 di; hydrolyzes diadenosine polyphosphate YP_248601.1 Similar to: HI0902, Y902_HAEIN YP_248602.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_248603.1 TS; TSase; ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_248604.1 Similar to: HI0906, YFHC_HAEIN YP_248605.1 Similar to: HI0907, Y907_HAEIN YP_248606.1 Similar to: HI0908, Y908_HAEIN YP_248607.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_248608.1 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase; Similar to: HI0910, MUTT_HAEIN YP_248609.1 K(+)/H(+) antiporter; Similar to: HI0911, KEFX_HAEIN YP_248610.1 Similar to: HI0912, Y912_HAEIN YP_248611.2 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_248612.1 EF-Ts; EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_248613.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_248614.1 Similar to: HI0916, OM26_HAEIN YP_248615.1 Outer membrane protein D15; Similar to: HI0917, D152_HAEIN YP_248616.1 Similar to: HI0918, YAEL_HAEIN YP_248617.1 CDP-diglyceride synthetase; CDP-diglyceride pyrophosphorylase; CDP-diacylglycerol synthase; CDS; CTP:phosphatidate cytidylyltransferase; CDP-DAG synthase; CDP-DG synthetase; Similar to: HI0919, CDSA_HAEIN YP_248618.1 UPP synthetase; Di-trans-poly-cis-decaprenylcistransferase; undecaprenyl diphosphate synthase; UDS; Similar to: HI0920, UPPS_HAEIN YP_248619.1 leucine--tRNA ligase; LeuRS; leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_248620.1 Similar to: HI0922, Y922_HAEIN YP_248621.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_248622.1 glycine--tRNA ligase beta chain; GlyRS; glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_248624.1 Similar to: HI0925, Y925_HAEIN YP_248625.1 Similar to: HI0926, Y926_HAEIN YP_248626.1 glycine--tRNA ligase alpha chain; GlyRS; glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_248627.1 Similar to: HI0928, CATA_HAEIN YP_248628.1 Similar to: HI0929, YGIC_HAEIN YP_248629.1 Similar to: HI0930, Y930_HAEIN YP_248630.1 Similar to: HI0931, Y931_HAEIN YP_248631.1 2-phosphoglycerate dehydratase; 2-phospho-D-glycerate hydro-lyase; enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_248632.1 Similar to: HI0933, YHIN_HAEIN YP_248633.1 Similar to: HI0934, NRFF_HAEIN YP_248634.1 cytochrome c biogenesis protein nrfX; Similar to: HI0935, NRFX_HAEIN YP_248635.1 Similar to: HI0936, NRFE_HAEIN YP_248636.1 IMPase; inositol-1-phosphatase; I-1-Pase; Similar to: HI0937, SUHB_HAEIN YP_248637.1 Similar to: HI0938, Y938_HAEIN YP_248638.1 Similar to: HI0939, Y939_HAEIN YP_248639.1 Similar to: HI0940, Y940_HAEIN YP_248640.1 Similar to: HI0941, Y941_HAEIN YP_248641.1 Similar to: HI0942, EX5C_HAEIN YP_248642.1 Similar to: HI0943, YBAD_HAEIN; Zn-ribbon and ATP-cone domains YP_248643.1 riboflavin-specific deaminase; HTP reductase; Similar to: HI0944, RIBD_HAEIN YP_248644.1 Similar to: HI0945, DEGS_HAEIN YP_248645.1 FAPY-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_248646.1 DABA decarboxylase; DABA-DC; Similar to: HI0946.1, DDC_HAEIN YP_248647.1 Similar to: HI0947, Y947_HAEIN YP_248648.1 Similar to: HI0948, Y948_HAEIN YP_248649.1 L-diaminobutyric acid transaminase; diaminobutyrate transaminase; DABA aminotransferase; DABA-AT; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_248650.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_248651.1 required for 70S ribosome assembly YP_248652.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_248653.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_248654.1 dUTPase; dUTP pyrophosphatase; catalyzes the formation of dUMP from dUTP YP_248655.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_248656.1 Similar to: Y956_HAEIN YP_248657.1 cAMP receptor protein; cAMP-regulatory protein; complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_248658.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_248659.1 N-acetyl-beta-glucosaminidase; Beta-N-acetylhexosaminidase; hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_248660.1 Similar to: HI0960, Y960_HAEIN YP_248661.1 Similar to: HI0961, YCFF_HAEIN YP_248662.1 isoleucine--tRNA ligase; IleRS; IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_248663.1 flavokinase; FAD pyrophosphorylase; FAD synthetase; catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_248664.1 Similar to: HI0964, MVIN_HAEIN YP_248665.2 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_248666.1 Similar to: HI0966, Y966_HAEIN YP_248667.1 dihydroxynaphthoic acid synthetase; DHNA synthetase; catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_248668.1 OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; O-succinylbenzoic acid synthase; catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_248669.1 3-dehydroquinase; Type II DHQase; catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_248670.1 BCCP; composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_248671.1 A subunit of acetyl-CoA carboxylase; an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_248672.1 Similar to: HI0974.1, YHDT_HAEIN YP_248673.1 pantothenate permease; mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_248674.1 Similar to: HI0976.1, Y97X_HAEIN YP_248675.1 L11 Mtase; methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_248676.1 Similar to: HI0979, DUSB_HAEIN YP_248677.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_248678.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_248679.1 phosphofructokinase; phosphohexokinase; catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_248680.1 Similar to: HI0983, Y983_HAEIN YP_248681.1 Similar to: HI0984, Y984_HAEIN YP_248682.1 DNA processing chain A; Similar to: HI0985, SMF_HAEIN YP_248683.1 Alpha-isopropylmalate synthase; Alpha-IPM synthetase; catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_248684.1 beta-IPM dehydrogenase; IMDH; 3-IPM-DH; catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_248685.1 isopropylmalate isomerase; alpha-IPM isomerase; IPMI; dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_248686.1 isopropylmalate isomerase; alpha-IPM isomerase; IPMI; catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_248687.1 IgA protease; Similar to: HI0990, IGA_NEIGO YP_248688.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_248689.1 binds the polymerase to DNA and acts as a sliding clamp YP_248690.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_248691.1 Similar to: HI0994, TBP1_HAEIN YP_248692.1 Similar to: HI0995, TBP2_HAEIN YP_248693.1 Similar to: HI0997, Y997_HAEIN YP_248694.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_248695.1 RNaseP protein; RNase P protein; protein C5; protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_248696.1 Similar to: HI1000, YA00_HAEIN YP_248697.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_248698.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_248699.1 PPIase D; rotamase D; Similar to: HI1004, PPID_HAEIN YP_248700.1 Similar to: HI1005, YA05_HAEIN YP_248701.1 prolipoprotein signal peptidase; signal peptidase II; SPase II; lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_248702.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_248703.1 Similar to: HI1008, YBAV_HAEIN YP_248704.1 Similar to: HI1019, TBPA_HAEIN YP_248705.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_248706.1 Similar to: HI1021, THIQ_HAEIN YP_248707.1 biotin synthetase; Similar to: HI1022, BIOB_HAEIN YP_248708.1 TK; catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_248709.1 PSP; O-phosphoserine phosphohydrolase; PSPase; catalyzes the formation of serine from O-phosphoserine YP_248710.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_248711.1 responsible for the influx of magnesium ions YP_248712.1 Similar to: HI1036, YGGT_HAEIN YP_248713.1 Similar to: HI1037, YAFJ_HAEIN YP_248715.1 Similar to: HI1038, YA38_HAEIN YP_248717.1 Similar to: HI1043, YA43_HAEIN YP_248718.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane YP_248719.1 DMSO reductase anchor subunit; Similar to: HI1045, DMSC_HAEIN YP_248720.1 DMSO reductase iron-sulfur subunit; Similar to: HI1046, DMSB_HAEIN YP_248721.1 DMSO reductase; Similar to: HI1047, DMSA_HAEIN YP_248722.1 Similar to: HI1048, YA48_HAEIN YP_248723.1 Similar to: HI1049, YA49_HAEIN YP_248724.1 Similar to: HI1050, YA50_HAEIN YP_248725.1 Similar to: HI1051, YA51_HAEIN YP_248726.1 Similar to: HI1052, YA52_HAEIN YP_248727.1 Similar to: HI1053, YA53_HAEIN YP_248728.1 Similar to: HI1054, YA54_HAEIN YP_248729.1 Similar to: HI1055, T3RH_HAEIN YP_248730.1 RNase HII; RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_248731.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_248732.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_248733.1 (3R)-hydroxymyristoyl ACP dehydrase; in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_248734.1 Similar to: HI1064, YA64_HAEIN YP_248735.1 UK; uridine monophosphate kinase; UMP kinase; Catalyzes the phosphorylation of UMP to UDP YP_248736.1 Similar to: HI1066, NRFD_HAEIN YP_248737.1 Similar to: HI1067, NRFC_HAEIN YP_248738.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia YP_248739.1 ammonia-forming cytochrome c nitrite reductase; cytochrome c nitrite reductase; catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_248740.2 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_248741.1 Similar to: HI1073, YGDD_HAEIN YP_248742.1 Similar to: HI1074, YEAL_HAEIN YP_248743.1 Similar to: HI1075, CYOB_HAEIN YP_248744.1 Similar to: HI1076, CYOA_HAEIN YP_248745.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_248746.1 NR; Similar to: HI1077.1, YA7B_HAEIN YP_248747.1 Similar to: HI1078, YA78_HAEIN YP_248748.1 Similar to: HI1079, YA79_HAEIN YP_248749.1 Similar to: HI1080, YA80_HAEIN YP_248750.1 enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT; adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_248751.1 Similar to: HI1082, YRBA_HAEIN YP_248752.1 Similar to: HI1083, YA83_HAEIN YP_248753.1 Similar to: HI1084, YRBC_HAEIN YP_248754.1 Similar to: HI1085, YRBD_HAEIN YP_248755.1 Similar to: HI1086, YRBE_HAEIN YP_248756.1 Similar to: HI1087, YRBF_HAEIN YP_248757.1 Mn; Similar to: HI1088, SODM_HAEIN YP_248758.1 cytochrome c-type biogenesis ATP-binding protein CcmA; ATP-binding protein; required for proper cytochrome c maturation YP_248759.1 cytochrome c-type biogenesis protein CcmB; Similar to: HI1090, CCMB_HAEIN YP_248760.1 cytochrome c-type biogenesis protein CcmC; Similar to: HI1091, CCMC_HAEIN YP_248761.1 cytochrome c-type biogenesis protein CcmD; Similar to: HI1092, CCMD_HAEIN YP_248762.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_248763.1 Similar to: HI1094, CCMF_HAEIN YP_248764.1 cytochrome c biogenesis protein CcmG; Similar to: HI1095, DSBE_HAEIN YP_248766.1 Similar to: HI1099, YA99_HAEIN YP_248767.2 polydeoxyribonucleotide synthase; this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_248768.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_248769.1 role in sulfur assimilation YP_248770.1 O-acetylserine sulfhydrylase; O-acetylserine (Thiol)-lyase; CSase; Similar to: HI1103, CYSK_HAEIN YP_248771.1 Similar to: HI1105, RFAF_HAEIN YP_248772.1 Similar to: HI1106, XYLR_HAEIN YP_248773.1 Similar to: HI1107, YB07_HAEIN YP_248774.1 Similar to: PATB_BACSU YP_248775.1 catalyzes the interconversion of D-xylose to D-xylulose YP_248776.1 xylulokinase; Similar to: HI1113, XYLB_HAEIN YP_248777.1 ADP-glyceromanno-heptose 6-epimerase; catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_248778.1 Similar to: HI1115, THIX_HAEIN YP_248779.1 phosphodeoxyriboaldolase; deoxyriboaldolase; DERA; catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_248780.1 Similar to: HI1117, COMM_HAEIN YP_248781.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_248782.1 Similar to: HI1119, YB19_HAEIN YP_248783.1 Similar to: HI1120, OPPF_HAEIN YP_248784.1 Similar to: HI1121, OPPD_HAEIN YP_248785.1 Similar to: HI1122, OPPC_HAEIN YP_248786.1 Similar to: HI1123, OPPB_HAEIN YP_248787.1 Similar to: HI1124, OPPA_HAEIN YP_248788.1 Maintains the balance of metabolites in the pentose-phosphate pathway YP_248789.1 Similar to: HI1126.1, YB2X_HAEIN YP_248790.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_248791.1 Similar to: HI1130, MRAW_HAEIN YP_248792.1 Similar to: HI1131, FTSL_HAEIN YP_248793.1 peptidoglycan glycosyltransferase 3; penicillin-binding protein 3; PBP-3; Similar to: HI1132, FTSI_HAEIN YP_248794.1 UDP-N-acetylmuramyl-tripeptide synthetase; Meso-diaminopimelate-adding enzyme; UDP-MurNAc-tripeptide synthetase; involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_248795.1 UDP-MurNAc-pentapeptide synthetase; D-alanyl-D-alanine-adding enzyme; Similar to: HI1134, MURF_HAEIN YP_248796.1 UDP-MurNAc-pentapeptide phosphotransferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_248797.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; D-glutamic acid adding enzyme; UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_248798.1 Similar to: HI1137, FTSW_HAEIN YP_248799.1 pentapeptide; undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_248800.1 UDP-N-acetylmuramoyl-L-alanine synthetase; Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_248801.1 D-alanylalanine synthetase; D-Ala-D-Ala ligase; D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_248802.1 Similar to: HI1141, FTSQ_HAEIN YP_248803.1 Similar to: HI1142, FTSA_HAEIN YP_248804.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_248805.1 UDP-3-O-acyl-GlcNAc deacetylase; zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_248806.1 CM; PDT; Similar to: HI1145, PHEA_HAEIN YP_248807.1 Similar to: HI1146, YB46_HAEIN YP_248808.1 Similar to: HI1147, PTSN_HAEIN YP_248809.1 Similar to: HI1148, YHBG_HAEIN YP_248810.1 Similar to: HI1149, YHBN_HAEIN YP_248811.1 Similar to: HI1150, YRBK_HAEIN YP_248812.1 Similar to: HI1151, YJGA_HAEIN YP_248813.1 Similar to: HI1152, PMBA_HAEIN YP_248814.1 HPRT; Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively YP_248815.1 Similar to: HI1154, YDJN_HAEIN YP_248816.1 Class III anaerobic ribonucleotide reductase small component; activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_248817.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_248818.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_248819.1 TRXR; Similar to: HI1158, TRXB_HAEIN YP_248820.1 Similar to: HI1159, YBBN_HAEIN YP_248821.1 protoheme ferro-lyase; heme synthetase; protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_248822.1 Similar to: HI1161, YB61_HAEIN YP_248823.1 Similar to: HI1163, YDIJ_HAEIN YP_248824.1 OMP P5-homologous adhesin; Similar to: HI1164, OM53_HAEIN YP_248825.1 Similar to: HI1165, YDHD_HAEIN YP_248826.1 imidazole acetol-phosphate transaminase 2; catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_248827.1 PSAT; catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_248828.1 Similar to: HI1168, YB68_HAEIN YP_248829.1 Similar to: HI1169, YB69_HAEIN YP_248830.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine YP_248831.1 glutamine amido-transferase; catalyzes the formation of anthranilate from chorismate and glutamine; functions in tryptophan biosynthesis YP_248832.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_248833.1 Similar to: HI1173, SPRT_HAEIN YP_248834.1 Similar to: HI1174, OPA_HAEIN YP_248835.1 Similar to: HI1176 YP_248836.1 with ArtPQJI acts to transport arginine across the inner membrane YP_248837.1 with ArtPMJI transports arginine across the inner membrane YP_248838.1 Similar to: HI1179, ARTI_HAEIN YP_248839.1 With ArtMQJI transports arginine across the inner membrane YP_248840.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_248841.1 polydeoxyribonucleotide synthase; catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_248842.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_248843.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_248844.1 Similar to: HI1186, DPPC_HAEIN YP_248845.1 Similar to: HI1187, DPPB_HAEIN YP_248846.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_248847.1 Similar to: HI1189, YGCF_HAEIN YP_248848.1 Similar to: HI1190, YB90_HAEIN YP_248849.1 Similar to: HI1191, YBAX_HAEIN YP_248850.1 Similar to: HI1192, YB92_HAEIN YP_248851.1 BCAT; catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_248852.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_248853.1 Similar to: HI1195, YGDE_HAEIN YP_248854.1 SCS-beta; catalyzes the interconversion of succinyl-CoA and succinate YP_248855.1 SCS-alpha; Similar to: HI1197, SUCD_HAEIN YP_248856.1 Similar to: HI1198, YCIO_HAEIN YP_248857.1 pseudouridylate synthase; Uracil hydrolyase; Similar to: HI1199, RLUB_HAEIN YP_248858.1 Cys regulon transcriptional activator; LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_248859.1 involved in methylation of ribosomal protein L3 YP_248860.1 Similar to: HI1202, YC02_HAEIN YP_248861.1 phosphotransacetylase; catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_248862.1 acetokinase; AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_248863.1 Similar to: HI1205, YC05_HAEIN YP_248864.1 Similar to: HI1206, CVPA_HAEIN YP_248865.1 glutamine phosphoribosylpyrophosphate amidotransferase; ATASE; GPATase; Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_248866.1 Similar to: HI1208, YFCH_HAEIN YP_248867.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_248868.1 oxidizes malate to oxaloacetate YP_248869.1 Lysine--tRNA ligase; LysRS; class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_248870.1 RF-2; Similar to: HI1561, RF2_HAEIN YP_248871.1 Similar to: HI1213, DSBC_HAEIN YP_248872.1 Similar to: HI1214, RECJ_HAEIN YP_248873.1 Similar to: HI1215, YC15_HAEIN YP_248874.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_248875.1 Similar to: HI1217, YC17_HAEIN YP_248876.1 Similar to: HI1218, YC18_HAEIN YP_248877.1 D-fructose-1,6-bisphosphate 1-phosphohydrolase; FBPase; catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_248878.1 pseudouridylate synthase I; pseudouridine synthase I; Uracil hydrolyase; mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_248879.1 Similar to: HI1643, YEIH_HAEIN YP_248880.1 Similar to: HI1642, SAPF_HAEIN YP_248881.1 Similar to: HI1641, SAPD_HAEIN YP_248882.1 Similar to: HI1640, SAPC_HAEIN YP_248883.1 Similar to: HI1639, SAPB_HAEIN YP_248884.1 Similar to: HI1638, SAPA_HAEIN YP_248885.1 Similar to: HI1637, YCJX_HAEIN YP_248886.1 PEPCase; PEPC; catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_248887.1 Purine nucleotide synthesis repressor; binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_248888.2 tetrahydrodipicolinate N-succinyltransferase; THP succinyltransferase; tetrahydropicolinate succinylase; catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_248889.1 IMP--aspartate ligase; AdSS; AMPSase; catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_248890.1 Similar to: HI1632, YG32_HAEIN YP_248891.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_248892.1 Similar to: HI1629, YG29_HAEIN YP_248893.1 Similar to: HI1628, YHCB_HAEIN YP_248894.1 Similar to: HI1627, YG27_HAEIN YP_248895.1 Similar to: HI1626, YG26_HAEIN YP_248896.1 Similar to: HI1625, YG25_HAEIN YP_248897.1 Similar to: HI1623, ZNTR_HAEIN YP_248898.1 Similar to: HI1624, YG24_HAEIN YP_248899.1 Similar to: HI1622, YG22_HAEIN YP_248900.1 catalyzes the ATP-dependent transport of cobalt YP_248901.1 Similar to: HI1620, YG20_HAEIN YP_248902.1 Similar to: HI1618, YG18_HAEIN YP_248903.1 transaminase A; ASPAT; catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_248904.1 AIR carboxylase; AIRC; With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_248905.1 AIR carboxylase; AIRC; Catalyzes a step in the de novo purine nucleotide biosynthetic pathway YP_248908.1 alpha-aminoacylpeptide hydrolase; Similar to: HI1614, AMPN_HAEIN YP_248909.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_248910.1 Na(+)/drug antiporter; multidrug-efflux transporter; NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_248911.1 Regulatory factor involved in maltose metabolism YP_248912.1 tyrosine--tRNA ligase; TyrRS; catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_248913.1 RPPK; phosphoribosyl pyrophosphate synthetase; P-Rib-PP synthetase; PRPP synthetase; catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_248914.1 CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase; An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_248915.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_248916.1 tRNA adenylyltransferase; tRNA CCA-pyrophosphorylase; CCA-adding enzyme; catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_248917.1 Similar to: HI1605, YGIM_HAEIN YP_248918.1 Similar to: HI1604, YG04_HAEIN YP_248919.1 Similar to: HI1603, YG03_HAEIN YP_248920.1 Similar to: HI1602, YG02_HAEIN YP_248921.1 Similar to: HI1601, YG01_HAEIN YP_248922.1 Similar to: HI1600, YG00_HAEIN YP_248923.1 Similar to: HI1599, YF99_HAEIN YP_248930.1 Similar to: HI1598, YGIF_HAEIN YP_248931.1 DNA repair protein sms homolog; Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_248932.2 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_248933.1 Similar to: HI1592, FTSK_HAEIN YP_248934.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_248935.1 Similar to: HI1590, YCAJ_HAEIN YP_248937.1 cytosine-specific methyltransferase BepI-like; Similar to: MTB1_BREEP YP_248938.1 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS; catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_248939.1 Formyl-FH(4) hydrolase; produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_248940.1 Similar to: HI1587, HNS_HAEIN YP_248941.1 Similar to: HI1586, YF86_HAEIN YP_248943.1 AHAS; acetohydroxy-acid synthase large subunit; ALS; acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate YP_248944.1 AHAS; acetohydroxy-acid synthase small subunit; ALS; with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_248945.1 arginine--tRNA ligase; ArgRS; catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_248946.1 Similar to: HI1582, YECM_HAEIN YP_248948.1 15 kDa lipoprotein; PAL cross-reacting lipoprotein; Similar to: HI1579, PCP_HAEIN YP_248949.1 Similar to: HI1578, YF78_HAEIN YP_248950.2 GPI; phosphoglucose isomerase; PGI; phosphohexose isomerase; PHI; functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_248951.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_248952.1 unwinds double stranded DNA YP_248953.1 PK; catalyzes the formation of phosphoenolpyruvate from pyruvate YP_248954.1 Similar to: INTA_ECOLI YP_248960.1 cytosine-specific methyltransferase Bsp6I-like YP_248961.1 Required for efficient pilin antigenic variation YP_248963.1 SSB; Helix-destabilizing protein YP_248965.1 Similar to: YQAK_BACSU YP_248968.1 adenine-specific methyltransferase DpnIIB-like YP_248995.1 Similar to: HI1410, YE10_HAEIN YP_248997.1 Similar to: HI1407 YP_249019.1 Similar to: HI1403, VPH_BPHP1 YP_249020.1 Similar to: YO32_BPHP1 YP_249022.1 Similar to: HI1523, YF23_HAEIN YP_249025.1 Similar to: HI1571, YF71_HAEIN YP_249026.1 Similar to: HI1570, YF70_HAEIN YP_249028.1 Similar to: HI1563, YFCM_HAEIN YP_249031.1 Similar to: YBEQ_ECOLI YP_249036.1 RF-1; recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_249037.1 Similar to: HI1560, YF60_HAEIN YP_249038.1 M.HindHemKP; Similar to: HI1559, HEMK_HAEIN YP_249039.1 Similar to: HI1558, YF58_HAEIN YP_249040.1 phospho-2-dehydro-3-deoxyoctonate aldolase; 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase; KDO-8-phosphate synthetase; KDO 8-P synthase; KDOPS; catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_249041.1 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor YP_249042.1 Similar to: HI1555, LOLC_HAEIN YP_249043.1 7,8-diamino-pelargonic acid aminotransferase; DAPA aminotransferase; catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_249044.1 AONS; 8-amino-7-ketopelargonate synthase; 7-keto-8-amino-pelargonic acid synthetase; 7-KAP synthetase; L-alanine--pimelyl CoA ligase; catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_249045.1 Similar to: HI1552, YF52_HAEIN YP_249046.1 Similar to: HI1551, BIOC_HAEIN YP_249047.1 dethiobiotin synthase 2; DTB synthetase 2; DTBS 2; DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_249048.1 Similar to: HI1549, LOLD_HAEIN YP_249049.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_249050.1 phospho-2-keto-3-deoxyheptonate aldolase; DAHP synthetase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_249051.1 Similar to: HI1546, YF46_HAEIN YP_249052.1 involved in the import of serine and threonine coupled with the import of sodium YP_249053.1 Similar to: HI1544, YF44_HAEIN YP_249054.1 Similar to: HI1543, YCDY_HAEIN YP_249055.1 Similar to: HI1542, YDJA_HAEIN YP_249056.1 endopeptidase IV; Signal peptide peptidase; Similar to: HI1541, SPPA_HAEIN YP_249057.1 Similar to: HI1540, LICD_HAEIN YP_249058.1 CTP--phosphocholine cytidylyltransferase involved in choline phosphorylation of cell surface lipooligosaccharide epitopes; Similar to: HI1539, LICC_HAEIN YP_249059.1 choline uptake protein; Similar to: HI1538, LICB_HAEIN YP_249060.1 choline kinase involved in LOS biosynthesis; Similar to: HI1537, LIA2_HAEIN YP_249061.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_249062.1 beta-ketoacyl-ACP synthase I; KAS I; FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_249063.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_249064.1 Similar to: HI1531, RIMK_HAEIN YP_249065.1 glutamate permease; Similar to: HI1530, GLTS_HAEIN YP_249066.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_249067.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_249068.1 heat shock protein B; Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_249069.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_249071.1 Similar to: HI1300, UUP1_HAEIN YP_249072.1 Similar to: HI1342, UUP2_HAEIN YP_249073.1 Similar to: HI1301, YADF_HAEIN YP_249074.2 asparagine--tRNA ligase; AsnRS; catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_249075.1 DMRL synthase; lumazine synthase; riboflavin synthase beta chain; RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_249076.1 NusB; Regulates rRNA biosynthesis by transcriptional antitermination YP_249077.1 thiamine-phosphate kinase; Similar to: HI1305, THIL_HAEIN YP_249078.1 Similar to: HI1306, PGPA_HAEIN YP_249079.1 Similar to: HI1307, YD07_HAEIN YP_249080.1 DHPR; catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_249081.1 Similar to: HI1309, YFAE_HAEIN YP_249082.1 Similar to: HI1310, YD10_HAEIN YP_249083.1 phenylalanine--tRNA ligase alpha chain; PheRS; catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_249084.1 phenylalanine--tRNA ligase beta chain; PheRS; catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_249085.1 IHF-alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_249086.1 Similar to: HI1314, YD14_HAEIN YP_249088.1 Similar to: 53DR_BPKV4 YP_249089.1 regulatory protein SIR2 family; Similar to: NPD_ACTAC YP_249092.1 SIR2 family YP_249097.1 Similar to: HI1316, YD16_HAEIN YP_249098.1 Similar to: HI1317, YD17_HAEIN YP_249099.1 Similar to: HI1318, IF3_HAEIN YP_249100.2 Similar to: HI1319, RL35_HAEIN YP_249101.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_249102.1 Similar to: HI1321, EX5B_HAEIN YP_249103.1 Similar to: HI1322, EX5A_HAEIN YP_249104.1 Similar to: HI1323, YD23_HAEIN YP_249105.1 Similar to: HI1324, LONH_HAEIN YP_249106.1 Beta-hydroxydecanoyl thioester dehydrase; catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_249107.1 Similar to: HI1326, YD26_HAEIN YP_249108.1 Similar to: HI1327 YP_249109.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_249110.1 Similar to: HI1328.1, YD2A_HAEIN YP_249111.1 Similar to: HI1329 YP_249112.1 PBP-4; DD-peptidase; DD-carboxypeptidase; DD-endopeptidase; penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_249113.1 transcript cleavage factor greA; necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_249114.1 Similar to: HI1333, YHBY_HAEIN YP_249115.1 rRNA (uridine-2'-O-)-methyltransferase; 23S rRNA m2U2552 methyltransferase; Cell division protein ftsJ homolog; Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_249116.1 Similar to: HI1335, FTH1_HAEIN YP_249117.1 DHPS; dihydropteroate pyrophosphorylase; Similar to: HI1464, DHPS_HAEIN YP_249118.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_249119.1 Similar to: HI1462.2, SIXA_HAEIN YP_249120.1 Similar to: HI1339, YD39_HAEIN YP_249121.1 Similar to: HI1462, YE62_HAEIN YP_249124.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_249127.1 peptide methionine sulfoxide reductase MsrA; peptide methionine sulfoxide reductase MsrB; protein-methionine-S-oxide reductase; peptide Met(O) reductase; this fusion consists of methionine sulfoxide A reductase at the N-terminus and B at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion YP_249128.1 Similar to: HI1454, YE54_HAEIN YP_249129.1 Similar to: HI1453, YE53_HAEIN YP_249130.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_249131.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_249132.1 Similar to: HI1448, MOEA_HAEIN YP_249133.1 GTP-CH-I; involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_249134.1 Similar to: HI1446, YCGL_HAEIN YP_249135.1 dethiobiotin synthase 1; DTB synthetase 1; DTBS 1; DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_249136.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_249137.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_249138.1 forms a direct contact with the tRNA during translation YP_249139.1 Similar to: HI1441, SSPA_HAEIN YP_249140.1 Similar to: HI1440, SSPB_HAEIN YP_249141.1 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS; catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_249142.1 farnesyl-diphosphate synthase; FPP synthase; Similar to: HI1438, ISPA_HAEIN YP_249143.1 exonuclease VII small subunit; catalyzes the bidirectional exonucleolytic cleavage of DNA YP_249144.1 Required for the synthesis of the thiazole moiety YP_249145.1 Similar to: HI1436, YQCC_HAEIN YP_249146.1 pseudouridylate synthase; uracil hydrolyase; catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_249147.1 Similar to: HI1434.2 YP_249148.1 Similar to: HI1434.1, CSPD_HAEIN YP_249149.1 Similar to: HI1434, YBAK_HAEIN; predicted oligonucleotide binding domain YP_249150.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_249151.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_249152.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_249153.1 Similar to: HI1430, YDFG_HAEIN YP_249154.1 AIRS; phosphoribosyl-aminoimidazole synthetase; AIR synthase; catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_249155.1 GART; GAR transformylase; 5'-phosphoribosylglycinamide transformylase; glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_249156.1 Similar to: HI1427, YE27_HAEIN YP_249157.2 with UspC and UspD is involved in resistance to UV irradiation YP_249158.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_249159.1 Similar to: HI1424, YE24_HAEIN YP_249160.1 Similar to: HI1423, YE23_HAEIN YP_249161.1 Similar to: HI1422, YE22_HAEIN YP_249168.1 Similar to: RPC1_BPPH8 YP_249178.1 Similar to: HI1421, YE21_HAEIN YP_249180.1 Similar to: HI1418, YE18_HAEIN YP_249182.1 Similar to: HI1416, YE16_HAEIN YP_249183.1 Similar to: HI1415, YE15_HAEIN YP_249185.1 Similar to: HI1413, YE13_HAEIN YP_249187.1 Similar to: HI1411, YE11_HAEIN YP_249188.1 Similar to: HI1410, YE10_HAEIN YP_249189.1 Similar to: HI1409, YE09_HAEIN YP_249190.1 Similar to: HI1407, YE07_HAEIN YP_249191.1 Similar to: HI1405 YP_249192.1 dihydroorotate oxidase; DHodehase; DHODase; DHOD; catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_249193.1 Similar to: HI1400, TRPH_HAEIN YP_249194.1 Similar to: HI1399, YD99_HAEIN YP_249195.1 fumarase; class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_249197.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_249198.1 Similar to: HI1396, YD96_HAEIN YP_249199.1 Similar to: HI1395, YD95_HAEIN YP_249201.1 Similar to: HI1394, YD94_HAEIN YP_249203.1 valine--tRNA ligase; ValRS; valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_249205.1 IGPS; PRAI; monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_249206.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_249207.1 Similar to: HI1388.1, YD8A_HAEIN YP_249208.1 glutamine amido-transferase; TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_249209.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_249210.1 Similar to: HI1385, FTN2_HAEIN YP_249211.1 Similar to: HI1384, FTN1_HAEIN YP_249212.1 PBP; Similar to: HI1383, PSTS_HAEIN YP_249213.1 Similar to: HI1382, PSTC_HAEIN YP_249214.1 Similar to: HI1381, PSTA_HAEIN YP_249215.1 phosphate-transporting ATPase; ABC phosphate transporter; ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_249216.1 Similar to: HI1379, PHOB_HAEIN YP_249217.1 Similar to: HI1378, PHOR_HAEIN YP_249218.1 exonuclease I; DNA deoxyribophosphodiesterase; dRPase; Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_249219.1 Similar to: HI1376, YD76_HAEIN YP_249220.1 Similar to: HI1375, YD75_HAEIN YP_249221.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_249222.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_249223.1 endonuclease HaeII; R.HaeII; Similar to: T2H2_HAEAE YP_249224.1 cytosine-specific methyltransferase HaeII; M.HaeII; Similar to: MTH2_HAEAE YP_249225.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_249226.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_249227.1 Similar to: HI1371, YCCK_HAEIN YP_249228.1 Similar to: HI1370, MOP_HAEIN YP_249229.1 Similar to: HI1368, PQQL_HAEIN YP_249230.1 threonine--tRNA ligase; ThrRS; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_249231.1 ACP phosphodiesterase; Similar to: HI1366, ACPD_HAEIN YP_249232.1 Omega-protein; relaxing enzyme; untwisting enzyme; swivelase; catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_249233.1 Similar to: HI1364, YHCS_HAEIN YP_249234.1 pyridine nucleotide transhydrogenase subunit beta; nicotinamide nucleotide transhydrogenase subunit beta; catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_249235.1 pyridine nucleotide transhydrogenase subunit alpha; nicotinamide nucleotide transhydrogenase subunit alpha; forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_249236.1 Similar to: HI1361, PHSG_HAEIN YP_249237.1 Starch [bacterial glycogen] synthase; catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_249238.1 ADP-glucose synthase; ADP-glucose pyrophosphorylase; ADPGlc PPase; catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_249239.1 Similar to: HI1358, GLGX_HAEIN YP_249240.1 glycogen branching enzyme; BE; 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase; catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_249241.1 amylomaltase; disproportionating enzyme; D-enzyme; Similar to: HI1356, MALQ_HAEIN YP_249242.1 Similar to: HI1355, YD55_HAEIN YP_249243.1 glutamine--tRNA ligase; GlnRS; catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_249244.1 RNase G; cytoplasmic axial filament protein; involved in the processing of the 5'end of 16S rRNA YP_249245.1 proline permease; Similar to: HI1352, PUTP_HAEIN YP_249246.1 Similar to: HI1351, YECP_HAEIN YP_249247.1 cytidine aminohydrolase; CDA; Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_249248.1 Similar to: HI1349, YD49_HAEIN YP_249249.1 tripeptide aminopeptidase; aminotripeptidase; tripeptidase; catalyzes the release of the N-terminal amino acid from a tripeptide YP_249250.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase YP_249251.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component YP_249252.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component YP_249253.1 SPBP; Similar to: HI1344, POT1_HAEIN YP_249254.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_249255.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_249256.1 Similar to: HI1298, YOHK_HAEIN YP_249257.1 Similar to: HI1297, YOHJ_HAEIN YP_249258.1 Similar to: HI1296, YC96_HAEIN YP_249259.1 Similar to: HI1295, CSD_HAEIN YP_249260.1 Similar to: HI1293, YC93_HAEIN YP_249261.1 Similar to: HI1292, YC92_HAEIN YP_249262.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_249263.1 CM; PDH; catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_249264.1 tRNA pseudouridine 55 synthase; Psi55 synthase; pseudouridylate synthase; Uracil hydrolyase; catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_249265.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_249266.1 M.HindVIIP; Similar to: HI1287, T1MH_HAEIN YP_249267.1 S protein; S.HindVIIP; Similar to: HI1286, T1SH_HAEIN YP_249269.1 Similar to: HI1285, T1RH_HAEIN YP_249270.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_249271.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_249272.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_249279.1 Similar to: YO32_BPHP1 YP_249280.1 Similar to: HI1403, VPH_BPHP1 YP_249281.1 Similar to: VPI_BPP2 YP_249282.1 Similar to: VPJ_BPP2 YP_249300.1 Lysis protein; muramidase; endolysin; Similar to: LYCV_BPP1 YP_249304.1 Similar to: VPM_BPP2 YP_249305.1 Similar to: VPN_BPP2 YP_249306.1 Similar to: VPO_BPP2 YP_249307.1 Similar to: VPP_BPP2 YP_249308.1 Similar to: VPQ_BPP2 YP_249309.1 CMP-N-acetylneuraminic acid synthetase; CMP-NeuNAc synthetase; CMP-sialic acid synthetase; Similar to: HI1279, NEUA_HAEIN YP_249310.1 Similar to: HI1278, YC78_HAEIN YP_249311.2 Similar to: HI1277, MRP_HAEIN YP_249312.1 methionine--tRNA ligase; MetRS; methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_249313.1 with TehA confers resistance to tellurite YP_249314.1 glyoxalase II; Glx II; Similar to: HI1274, GLO2_HAEIN YP_249315.1 Similar to: HI1273, YC73_HAEIN YP_249316.1 Similar to: HI1266, YC66_HAEIN YP_249317.1 Similar to: HI1265, YCAO_HAEIN YP_249318.1 negatively supercoils closed circular double-stranded DNA YP_249319.1 homoserine O-trans-acetylase; homoserine transacetylase; HTA; Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine YP_249320.1 Similar to: HI1262, SANA_HAEIN YP_249321.1 folylpoly-gamma-glutamate synthetase; FPGS; Similar to: HI1261, FOLC_HAEIN YP_249322.1 ACCASE beta chain; catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_249323.1 Similar to: HI1259, HTOA_HAEIN YP_249324.1 TRCF; Similar to: HI1258, MFD_HAEIN YP_249325.1 Similar to: HI1257, YC57_HAEIN YP_249326.1 Similar to: HI1254, YC54_HAEIN YP_249327.1 Similar to: HI1253, YC53_HAEIN YP_249328.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_249329.1 Similar to: HI1251, YC51_HAEIN YP_249330.1 Similar to: HI1250, YC50_HAEIN YP_249331.1 Similar to: HI1249, YC49_HAEIN YP_249332.1 Similar to: HI1248, YC48_HAEIN YP_249333.1 UvrB; excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_249334.1 Similar to: HI1246, YC46_HAEIN YP_249335.1 NADP-ME; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_249336.1 Similar to: HI1244, YC44_HAEIN YP_249337.1 16S pseudouridylate 516 synthase; 16S pseudouridine 516 synthase; Uracil hydrolyase; Similar to: HI1243, RSUA_HAEIN YP_249338.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_249339.1 Similar to: HI1241, YC41_HAEIN YP_249340.1 Similar to: HI1240, YICG_HAEIN YP_249341.1 GPR; glutamate-5-semialdehyde dehydrogenase; glutamyl-gamma-semialdehyde dehydrogenase; GSA dehydrogenase; Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_249342.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_249343.1 Heat shock protein 70; Heat shock 70 kDa protein; HSP70; heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_249344.1 Similar to: HI1236, YC36_HAEIN YP_249345.1 MGS; catalyzes the formation of methylglyoxal from glycerone phosphate YP_249346.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_249347.1 E2; Similar to: HI1232, ODP2_HAEIN YP_249348.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes; E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_249350.1 APRT; catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_249351.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_249352.1 UMP pyrophosphorylase; UPRTase; Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_249353.1 Uracil transporter; Similar to: HI1227, URAA_HAEIN YP_249354.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_249355.1 Similar to: HI1225, YCIH_HAEIN YP_249356.1 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_249357.1 Similar to: HI1223, YCIM_HAEIN YP_249358.1 Similar to: HI1222, YCIS_HAEIN YP_249359.1 IHF-beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_249360.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_249361.1 CK; cytidine monophosphate kinase; CMP kinase; Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_249362.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_249363.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_249364.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_249365.1 Similar to: HI1650 YP_249366.1 Similar to: HI1652, NLPC_HAEIN YP_249367.1 Similar to: TLDD_HAEIN YP_249368.1 Similar to: HI1654, YRAL_HAEIN YP_249369.1 Similar to: HI1655, YRAM_HAEIN YP_249370.1 Similar to: HI1656, YG56_HAEIN YP_249371.1 Similar to: HI1657, YRAO_HAEIN YP_249372.1 Similar to: HI1658, YRAP_HAEIN YP_249373.1 ribonucleotide reductase; Catalyzes the rate-limiting step in dNTP synthesis YP_249374.1 ribonucleotide reductase small subunit; B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_249375.1 E2; Similar to: HI1661, ODO2_HAEIN YP_249376.1 alpha-ketoglutarate dehydrogenase; SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_249377.1 Similar to: HI1663, YCBL_HAEIN YP_249378.1 Similar to: HI1664, YG64_HAEIN YP_249379.1 Similar to: HI1666, YCBK_HAEIN YP_249380.1 Similar to: HI1667, YCBB_HAEIN YP_249381.1 protease Re; C-terminal processing peptidase; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_249382.1 affects solute and DNA transport through an unknown mechanism YP_249383.1 Similar to: HI1671, YEBS_HAEIN YP_249384.1 Similar to: HI1672, YEBT_HAEIN YP_249385.1 MPT synthase subunit 2; molybdopterin synthase subunit 2; molybdenum cofactor biosynthesis protein E; molybdopterin converting factor large subunit; Similar to: HI1673, MOAE_HAEIN YP_249386.1 MPT synthase subunit 1; molybdopterin synthase subunit 1; molybdenum cofactor biosynthesis protein D; molybdopterin converting factor small subunit; catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_249387.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_249388.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_249389.1 Similar to: HI1677, YTFE_HAEIN YP_249390.1 Similar to: HI1677, YTFE_HAEIN YP_249391.1 Similar to: HI1678, YG78_HAEIN YP_249392.1 KDO 8-P phosphatase; Similar to: HI1679, KDOP_HAEIN YP_249396.1 Similar to: HI1680, YCCS_HAEIN YP_249397.1 Similar to: HI1681, YG81_HAEIN YP_249398.1 SohB; periplasmic protein; member of the peptidase S49 family YP_249399.1 Similar to: HI1683, RNFA_HAEIN YP_249400.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_249401.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_249402.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_249403.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_249404.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_249405.1 DNA-(apurinic or apyrimidinic site) lyase; Similar to: HI1689, END3_HAEIN YP_249406.1 Similar to: HI1690, YG90_HAEIN YP_249407.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_249408.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_249409.1 Similar to: HI1693, MODA_HAEIN YP_249410.1 Similar to: HI1694, MODE_HAEIN YP_249411.1 Similar to: HI1695, YG95_HAEIN YP_249412.1 Similar to: HI1696, YG96_HAEIN YP_249413.1 Similar to: HI1697, LSG4_HAEIN YP_249414.1 Similar to: HI1698, YG98_HAEIN YP_249415.1 beta-galactoside alpha-2,3-sialyltransferase; Alpha 2,3-ST; lipooligosaccharide sialyltransferase; Similar to: HI1699, LST_HAEIN YP_249416.1 Similar to: HI1700, LSG1_HAEIN YP_249417.1 Similar to: HI1701, YH01_HAEIN YP_249418.1 Similar to: HI1703, YJGQ_HAEIN YP_249419.1 Similar to: HI1704, YJGP_HAEIN YP_249420.1 aminopeptidase A; leucine aminopeptidase; LAP; Leucyl aminopeptidase; catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_249421.1 Similar to: HI1706, YH06_HAEIN YP_249422.1 Similar to: HI1707, QSEC_HAEIN YP_249423.1 Similar to: HI1708, QSEB_HAEIN YP_249424.1 Similar to: HI1709, YGIW_HAEIN YP_249425.1 EIIA-Glc; glucose-permease IIA component; phosphotransferase enzyme II, A component; EIII-Glc; functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_249426.1 phosphotransferase system, enzyme I; Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_249427.1 histidine-containing protein; Similar to: HI1713, PTHP_HAEIN YP_249428.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_249429.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_249430.1 Similar to: HI1716, RFE_HAEIN YP_249431.1 PII uridylyl-transferase; uridylyl removing enzyme; UTase; Similar to: HI1719, GLND_HAEIN YP_249432.1 MAP; peptidase M; catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_249433.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_249434.1 Similar to: HI1724, YH24_HAEIN YP_249435.1 PBP-1b; PBP1b; Murein polymerase; peptidoglycan glycosyltransferase; peptidoglycan TGase; DD-transpeptidase; Similar to: HI1725, PBPB_HAEIN YP_249436.1 SAICAR synthetase; catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_249437.1 citrulline--aspartate ligase; catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_249438.1 Similar to: HI1728, YH28_HAEIN YP_249439.1 Similar to: HI1729, YH29_HAEIN YP_249440.1 Similar to: HI1730, YBGK_HAEIN YP_249441.1 Similar to: HI1731, YBGJ_HAEIN YP_249442.1 ribonuclease II; RNase II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_249443.1 NADH-dependent enoyl-ACP reductase; Similar to: HI1734, FABI_HAEIN YP_249444.1 RF-3; stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_249445.1 Similar to: HI1736, YH36_HAEIN YP_249446.1 Similar to: HI1737, YH37_HAEIN YP_249447.1 Similar to: HI1738, YH38_HAEIN YP_249448.1 Similar to: HI1739, METR_HAEIN YP_249449.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_249450.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_249451.1 catalyzes branch migration in Holliday junction intermediates YP_249452.1 diphosphate; (ppGpp)ase; Penta-phosphate guanosine-3'-pyrophosphohydrolase; Similar to: HI1741, SPOT_HAEIN YP_249453.1 transcriptase omega chain; RNA polymerase omega subunit; promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_249454.1 GMP kinase; Essential for recycling GMP and indirectly, cGMP