-- dump date 20140619_104153 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 281310000001 SEQ_END SEQ_END NC_007146.2 1914490 1914490 DR NC_007146.2; contig end 1914490..1914490 Haemophilus influenzae 86-028NP YP_247664.1 CDS gapA NC_007146.2 2 1021 D GAPDH; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 2..1021 Haemophilus influenzae 86-028NP 3429406 YP_247665.1 CDS NTHI0002 NC_007146.2 1191 3014 D Long-chain acyl-CoA synthetase; LACS; Similar to: HI0002, LCFH_HAEIN; long chain fatty acid CoA ligase 1191..3014 Haemophilus influenzae 86-028NP 3429407 YP_247666.1 CDS NTHI0003 NC_007146.2 3051 3839 R Similar to: HI0003, Y003_HAEIN; hypothetical protein complement(3051..3839) Haemophilus influenzae 86-028NP 3429408 YP_247667.1 CDS NTHI0004 NC_007146.2 3855 4319 R Similar to: HI0004, Y004_HAEIN; metalloprotease complement(3855..4319) Haemophilus influenzae 86-028NP 3429409 YP_247668.1 CDS fdhD NC_007146.2 4581 5393 R protein required for formate dehydrogenase activity; involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein complement(4581..5393) Haemophilus influenzae 86-028NP 3429410 YP_247669.1 CDS fdxG NC_007146.2 5664 8750 D formate dehydrogenase alpha subunit; FDH alpha subunit; Similar to: FDXG_HAEIN; Opal (TGA) stop encodes selenocysteine; formate dehydrogenase major subunit 5664..8750 Haemophilus influenzae 86-028NP 3429411 YP_247670.1 CDS fdxH NC_007146.2 8752 9690 D formate dehydrogenase beta subunit; FDH beta subunit; Similar to: HI0007, FDXH_HAEIN; formate dehydrogenase, iron-sulfur subunit 8752..9690 Haemophilus influenzae 86-028NP 3429412 YP_247671.1 CDS fdxI NC_007146.2 9683 10399 D formate dehydrogenase gamma subunit; FDH gamma subunit; Similar to: HI0008, FDXI_HAEIN; formate dehydrogenase, cytochrome B556 subunit 9683..10399 Haemophilus influenzae 86-028NP 3429413 YP_247672.1 CDS fdhE NC_007146.2 10469 11377 D required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 10469..11377 Haemophilus influenzae 86-028NP 3429414 YP_247673.1 CDS rimI NC_007146.2 11421 11861 R acetylating enzyme for N-terminal of ribosomal protein S18; alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase complement(11421..11861) Haemophilus influenzae 86-028NP 3429415 YP_247674.1 CDS holD NC_007146.2 11864 12268 R with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi complement(11864..12268) Haemophilus influenzae 86-028NP 3429416 YP_247675.1 CDS rsmC NC_007146.2 12374 13366 D rRNA (guanine-N(2)-)-methyltransferase; 16S rRNA m2G1207 methyltransferase; 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 12374..13366 Haemophilus influenzae 86-028NP 3429417 YP_247676.1 CDS era NC_007146.2 13434 14342 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(13434..14342) Haemophilus influenzae 86-028NP 3429418 YP_247677.1 CDS rnc NC_007146.2 14339 15022 R RNase III; cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(14339..15022) Haemophilus influenzae 86-028NP 3429419 YP_247678.1 CDS lepB NC_007146.2 15024 16073 R SPase I; Leader peptidase I; Similar to: HI0015, LEP_HAEIN; Signal peptidase I complement(15024..16073) Haemophilus influenzae 86-028NP 3429420 YP_247679.1 CDS lepA NC_007146.2 16082 17878 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(16082..17878) Haemophilus influenzae 86-028NP 3429421 YP_247680.1 CDS NTHI0022 NC_007146.2 18047 18430 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(18047..18430) Haemophilus influenzae 86-028NP 3429422 YP_247681.1 CDS ung NC_007146.2 18688 19347 D UDG; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 18688..19347 Haemophilus influenzae 86-028NP 3429423 YP_247682.1 CDS NTHI0026 NC_007146.2 19417 20841 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(19417..20841) Haemophilus influenzae 86-028NP 3429424 YP_247683.1 CDS NTHI0027 NC_007146.2 21224 22663 R Similar to: HI0020, YBHI_HAEIN; hypothetical protein complement(21224..22663) Haemophilus influenzae 86-028NP 3429425 YP_247684.1 CDS citG NC_007146.2 22665 24062 R 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase; Holo-citrate lyase synthase; Apo-ACP nucleodityltransferase; Similar to: HI0021, CIXG_HAEIN; CitXG complement(22665..24062) Haemophilus influenzae 86-028NP 3429426 YP_247685.1 CDS citF NC_007146.2 24243 25745 R citrase; citrate CoA-transferase subunit; Similar to: HI0022, CILA_HAEIN; citrate lyase alpha chain complement(24243..25745) Haemophilus influenzae 86-028NP 3429427 YP_247686.1 CDS citE NC_007146.2 25760 26635 R citrase; Citryl-CoA lyase subunit; Similar to: HI0023, CILB_HAEIN; citrate lyase beta chain complement(25760..26635) Haemophilus influenzae 86-028NP 3429428 YP_247687.1 CDS citD NC_007146.2 26632 26919 R citrate lyase gamma chain; acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma complement(26632..26919) Haemophilus influenzae 86-028NP 3429429 YP_247688.1 CDS citC NC_007146.2 26957 27964 R citrate lyase synthetase; acetate:SH-citrate lyase ligase; Similar to: HI0025, CITC_HAEIN; [citrate (pro-3S)-lyase] ligase complement(26957..27964) Haemophilus influenzae 86-028NP 3431068 YP_247689.1 CDS lipA NC_007146.2 28215 29177 R Lip-syn; lipoate synthase; catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(28215..29177) Haemophilus influenzae 86-028NP 3431069 YP_247690.1 CDS lipB NC_007146.2 29231 29869 R lipoate biosynthesis protein B; lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(29231..29869) Haemophilus influenzae 86-028NP 3431070 YP_247691.1 CDS NTHI0035 NC_007146.2 29871 30149 R Similar to: HI0028, Y028_HAEIN; hypothetical protein complement(29871..30149) Haemophilus influenzae 86-028NP 3431071 YP_247692.1 CDS dacA NC_007146.2 30205 31386 R D-alanyl-D-alanine carboxypeptidase fraction A; DD-peptidase; DD-carboxypeptidase; PBP-5; Similar to: HI0029, DACA_HAEIN; penicillin-binding protein 5 complement(30205..31386) Haemophilus influenzae 86-028NP 3431072 YP_247693.1 CDS rlpA NC_007146.2 31402 32265 R Similar to: HI0030, RLPA_HAEIN; RlpA-like protein complement(31402..32265) Haemophilus influenzae 86-028NP 3431073 YP_247694.1 CDS mrdB NC_007146.2 32318 33433 R Similar to: HI0031, RODA_HAEIN; rod shape-determining protein complement(32318..33433) Haemophilus influenzae 86-028NP 3431074 YP_247695.1 CDS mrdA NC_007146.2 33423 35378 R PBP-2; Similar to: HI0032, PBP2_HAEIN; penicillin-binding protein 2 complement(33423..35378) Haemophilus influenzae 86-028NP 3431075 YP_247696.1 CDS NTHI0041 NC_007146.2 35400 35867 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(35400..35867) Haemophilus influenzae 86-028NP 3431076 YP_247697.1 CDS NTHI0042 NC_007146.2 35921 36229 R Similar to: HI0034, YBEB_HAEIN; hypothetical protein complement(35921..36229) Haemophilus influenzae 86-028NP 3431077 YP_247698.1 CDS NTHI0043 NC_007146.2 36354 38009 R Similar to: HI0035, Y035_HAEIN; hypothetical protein complement(36354..38009) Haemophilus influenzae 86-028NP 3431078 YP_247699.1 CDS NTHI0044 NC_007146.2 38215 39993 D Similar to: HI0036, Y036_HAEIN; ABC transporter ATP-binding protein 38215..39993 Haemophilus influenzae 86-028NP 3431079 YP_247700.2 CDS mreB NC_007146.2 40123 41178 D functions in MreBCD complex in some organisms; rod shape-determining protein MreB 40123..41178 Haemophilus influenzae 86-028NP 3431080 YP_247701.1 CDS mreC NC_007146.2 41258 42313 D in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 41258..42313 Haemophilus influenzae 86-028NP 3431081 YP_247702.1 CDS mreD NC_007146.2 42313 42801 D Similar to: HI0039, MRED_HAEIN; rod shape-determining protein MreD 42313..42801 Haemophilus influenzae 86-028NP 3431082 YP_247703.1 CDS NTHI0048 NC_007146.2 42852 43628 R Similar to: HI0040, Y040_HAEIN; hypothetical protein complement(42852..43628) Haemophilus influenzae 86-028NP 3431083 YP_247704.1 CDS xthA NC_007146.2 43638 44441 R exonuclease III; EXO III; removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III complement(43638..44441) Haemophilus influenzae 86-028NP 3431084 YP_247705.1 CDS rluA2 NC_007146.2 44489 45163 R pseudouridylate synthase; Uracil hydrolyase; Similar to: HI0042, Y042_HAEIN; pseudouridine synthase complement(44489..45163) Haemophilus influenzae 86-028NP 3431085 YP_247706.1 CDS NTHI0051 NC_007146.2 45163 46227 R Similar to: HI0043, Y043_HAEIN; hypothetical protein complement(45163..46227) Haemophilus influenzae 86-028NP 3431086 YP_247707.1 CDS NTHI0052 NC_007146.2 46287 46949 R Similar to: HI0044, YCCA_HAEIN; FtsH-interacting integral membrane protein complement(46287..46949) Haemophilus influenzae 86-028NP 3431051 YP_247708.1 CDS NTHI0053 NC_007146.2 47276 47830 R Similar to: HI0045, YTFJ_HAEIN; hypothetical protein complement(47276..47830) Haemophilus influenzae 86-028NP 3431053 YP_247709.1 CDS phnA NC_007146.2 47897 48259 D Similar to: HI0046, PHNA_HAEIN; PhnA-like protein 47897..48259 Haemophilus influenzae 86-028NP 3431054 YP_247710.1 CDS eda NC_007146.2 48312 48950 R 2-keto-4-hydroxyglutarate aldolase; KHG-aldolase; phospho-2-dehydro-3-deoxygluconate aldolase; phospho-2-keto-3-deoxygluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; KDPG-aldolase; catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(48312..48950) Haemophilus influenzae 86-028NP 3431055 YP_247711.1 CDS uxuC NC_007146.2 48959 50362 R glucuronate isomerase; Uronic isomerase; catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(48959..50362) Haemophilus influenzae 86-028NP 3431056 YP_247712.1 CDS NTHI0057 NC_007146.2 50372 51229 R Converts D-mannonate to D-mannuronate; D-mannonate oxidoreductase complement(50372..51229) Haemophilus influenzae 86-028NP 3431057 YP_247713.1 CDS NTHI0060 NC_007146.2 52192 53463 R Similar to: HI0050, Y050_HAEIN; TRAP-type C4-dicarboxylate transport system, large permease complement(52192..53463) Haemophilus influenzae 86-028NP 3431059 YP_247714.1 CDS NTHI0061 NC_007146.2 53473 53970 R Similar to: HI0051, Y051_HAEIN; TRAP-type C4-dicarboxylate transport system, small permease complement(53473..53970) Haemophilus influenzae 86-028NP 3431060 YP_247715.1 CDS NTHI0062 NC_007146.2 54009 54995 R Similar to: HI0052, Y052_HAEIN; TRAP-type C4-dicarboxylate transport system, periplasmic component complement(54009..54995) Haemophilus influenzae 86-028NP 3431061 YP_247716.1 CDS NTHI0063 NC_007146.2 55022 56050 R Similar to: HI0053, Y053_HAEIN; hypothetical protein complement(55022..56050) Haemophilus influenzae 86-028NP 3431062 YP_247717.1 CDS uxuR NC_007146.2 56160 56960 D Similar to: HI0054, UXUR_HAEIN; uxu operon regulator 56160..56960 Haemophilus influenzae 86-028NP 3431063 YP_247718.1 CDS uxuA NC_007146.2 56988 58172 D D-mannonate hydrolase; catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 56988..58172 Haemophilus influenzae 86-028NP 3431064 YP_247719.1 CDS NTHI0066 NC_007146.2 58225 58938 R possibly involved in tellurium resistance; Similar to: HI0056, YGDQ_HAEIN; membrane protein TerC complement(58225..58938) Haemophilus influenzae 86-028NP 3431065 YP_247720.1 CDS uvrC NC_007146.2 59036 60865 R UvrC; excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(59036..60865) Haemophilus influenzae 86-028NP 3431066 YP_247721.1 CDS kdsB NC_007146.2 60867 61631 R CMP-KDO synthetase; CMP-2-keto-3-deoxyoctulosonic acid synthetase; CKS; CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase complement(60867..61631) Haemophilus influenzae 86-028NP 3431067 YP_247722.1 CDS lpxK NC_007146.2 61702 62700 R lipid A 4'-kinase; transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase complement(61702..62700) Haemophilus influenzae 86-028NP 3431087 YP_247723.1 CDS msbA NC_007146.2 62773 64536 R involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease protein complement(62773..64536) Haemophilus influenzae 86-028NP 3431088 YP_247724.1 CDS rec2 NC_007146.2 64577 66943 R Similar to: HI0061, REC2_HAEIN; recombination protein 2 complement(64577..66943) Haemophilus influenzae 86-028NP 3431089 YP_247725.1 CDS dksA NC_007146.2 67202 67639 D Similar to: HI0062, DKSA_HAEIN; DnaK suppressor protein 67202..67639 Haemophilus influenzae 86-028NP 3431090 YP_247726.1 CDS pcnB NC_007146.2 67887 69245 D Similar to: HI0063, PCNB_HAEIN; poly polymerase 67887..69245 Haemophilus influenzae 86-028NP 3431091 YP_247727.1 CDS folK NC_007146.2 69254 69736 D 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; HPPK; 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; PPPK; Similar to: HI0064, HPPK_HAEIN; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 69254..69736 Haemophilus influenzae 86-028NP 3431092 YP_247728.1 CDS NTHI0078 NC_007146.2 69812 70288 D Similar to: HI0065, YJEE_HAEIN; predicted ATPase activity; hypothetical protein 69812..70288 Haemophilus influenzae 86-028NP 3431093 YP_247729.1 CDS amiB NC_007146.2 70296 71594 D Similar to: HI0066, AMIB_HAEIN; N-acetylmuramoyl-L-alanine amidase 70296..71594 Haemophilus influenzae 86-028NP 3431094 YP_247730.1 CDS mutL NC_007146.2 71595 73484 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 71595..73484 Haemophilus influenzae 86-028NP 3431095 YP_247731.1 CDS miaA NC_007146.2 73492 74427 D IPP transferase; isopentenyl-diphosphate:tRNA isopentenyltransferase; IPTase; IPPT; IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 73492..74427 Haemophilus influenzae 86-028NP 3431096 YP_247732.1 CDS glnE NC_007146.2 74433 77378 D glutamine-synthetase adenylyltransferase; ATASE; catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 74433..77378 Haemophilus influenzae 86-028NP 3431097 YP_247733.1 CDS recN NC_007146.2 77463 79139 R recombination protein N; Similar to: HI0070, RECN_HAEIN; DNA repair protein RecN complement(77463..79139) Haemophilus influenzae 86-028NP 3431098 YP_247734.1 CDS ppnK NC_007146.2 79251 80069 R Poly(P)/ATP NAD kinase; catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(79251..80069) Haemophilus influenzae 86-028NP 3431099 YP_247735.1 CDS grpE NC_007146.2 80133 80837 D HSP-70 cofactor; with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 80133..80837 Haemophilus influenzae 86-028NP 3431100 YP_247736.1 CDS NTHI0086 NC_007146.2 80850 81194 R Similar to: HI0073, Y073_HAEIN; nucleotidyltransferase family; hypothetical protein complement(80850..81194) Haemophilus influenzae 86-028NP 3431101 YP_247737.1 CDS NTHI0087 NC_007146.2 81187 81627 R Similar to: HI0074, Y074_HAEIN; nucleotidyltransferase family; hypothetical protein complement(81187..81627) Haemophilus influenzae 86-028NP 3431102 YP_247738.1 CDS nrdD NC_007146.2 81908 84031 D Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 81908..84031 Haemophilus influenzae 86-028NP 3431103 YP_247739.1 CDS tesB NC_007146.2 84150 85010 D TEII; Similar to: HI0076, TESB_HAEIN; acyl-CoA thioesterase 84150..85010 Haemophilus influenzae 86-028NP 3431104 YP_247740.1 CDS cysS NC_007146.2 85171 86550 R cysteine--tRNA ligase; CysRS; catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(85171..86550) Haemophilus influenzae 86-028NP 3431105 YP_247741.1 CDS ppiB NC_007146.2 86653 87162 D PPIase B; rotamase B; Similar to: HI0079, PPIB_HAEIN; peptidyl-prolyl cis-trans isomerase B 86653..87162 Haemophilus influenzae 86-028NP 3431106 YP_247742.1 CDS NTHI0093 NC_007146.2 87166 87597 D Similar to: HI0080, YIFN_HAEIN; hypothetical protein 87166..87597 Haemophilus influenzae 86-028NP 3429430 YP_247743.1 CDS NTHI0095 NC_007146.2 87739 88527 D Similar to: HI0081, YJJV_HAEIN; deoxyribonuclease 87739..88527 Haemophilus influenzae 86-028NP 3429431 YP_247744.1 CDS NTHI0096 NC_007146.2 88589 88846 D hypothetical protein 88589..88846 Haemophilus influenzae 86-028NP 3429432 YP_247745.1 CDS NTHI0097 NC_007146.2 88857 89132 D hypothetical protein 88857..89132 Haemophilus influenzae 86-028NP 3429433 YP_247746.1 CDS trxA NC_007146.2 89182 89505 R TRX; Similar to: HI0084, THIO_HAEIN; thioredoxin complement(89182..89505) Haemophilus influenzae 86-028NP 3429434 YP_247747.1 CDS ddh NC_007146.2 89625 90620 R Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthes; D-lactate dehydrogenase complement(89625..90620) Haemophilus influenzae 86-028NP 3429435 YP_247748.1 CDS metB NC_007146.2 90633 91778 R CGS; O-succinylhomoserine (Thiol)-lyase; catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity; cystathionine gamma-synthase complement(90633..91778) Haemophilus influenzae 86-028NP 3429436 YP_247749.1 CDS NTHI0101 NC_007146.2 92334 93170 D chromosome partitioning ATPase 92334..93170 Haemophilus influenzae 86-028NP 3429440 YP_247750.1 CDS dnaB2 NC_007146.2 93172 94527 D Similar to: HI1574, DNAB_PASMU; replicative DNA helicase 93172..94527 Haemophilus influenzae 86-028NP 3429441 YP_247751.1 CDS NTHI0103 NC_007146.2 94520 96220 D hypothetical protein 94520..96220 Haemophilus influenzae 86-028NP 3429442 YP_247752.1 CDS NTHI0104 NC_007146.2 96220 96771 D hypothetical protein 96220..96771 Haemophilus influenzae 86-028NP 3429443 YP_247753.1 CDS NTHI0106 NC_007146.2 96921 98144 D hypothetical protein 96921..98144 Haemophilus influenzae 86-028NP 3429444 YP_247754.1 CDS NTHI0107 NC_007146.2 98441 99196 D hypothetical protein 98441..99196 Haemophilus influenzae 86-028NP 3429445 YP_247755.1 CDS NTHI0108 NC_007146.2 99196 99684 D hypothetical protein 99196..99684 Haemophilus influenzae 86-028NP 3429446 YP_247756.1 CDS ssb2 NC_007146.2 99930 100352 D SSB; Helix-destabilizing protein; binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 99930..100352 Haemophilus influenzae 86-028NP 3429447 YP_247757.1 CDS NTHI0110 NC_007146.2 100379 100897 D lipoprotein 100379..100897 Haemophilus influenzae 86-028NP 3429448 YP_247758.1 CDS NTHI0111 NC_007146.2 101113 101670 R hypothetical protein complement(101113..101670) Haemophilus influenzae 86-028NP 3429449 YP_247759.1 CDS topB2 NC_007146.2 101746 103806 D decatenates replicating daughter chromosomes; DNA topoisomerase III 101746..103806 Haemophilus influenzae 86-028NP 3429450 YP_247760.1 CDS NTHI0113 NC_007146.2 104691 105119 D hypothetical protein 104691..105119 Haemophilus influenzae 86-028NP 3429451 YP_247761.1 CDS NTHI0114 NC_007146.2 105131 105223 D hypothetical protein 105131..105223 Haemophilus influenzae 86-028NP 3429452 YP_247762.1 CDS NTHI0115 NC_007146.2 105234 105875 D hypothetical protein 105234..105875 Haemophilus influenzae 86-028NP 3429453 YP_247763.1 CDS NTHI0116 NC_007146.2 105910 106317 D hypothetical protein 105910..106317 Haemophilus influenzae 86-028NP 3429454 YP_247764.1 CDS radC2 NC_007146.2 106418 106888 D Similar to: HI0952; DNA repair radC-like protein 106418..106888 Haemophilus influenzae 86-028NP 3429455 YP_247765.1 CDS NTHI0118 NC_007146.2 106981 107577 D hypothetical protein 106981..107577 Haemophilus influenzae 86-028NP 3429456 YP_247766.1 CDS NTHI0119 NC_007146.2 107635 108399 D hypothetical protein 107635..108399 Haemophilus influenzae 86-028NP 3429457 YP_247767.1 CDS pilL NC_007146.2 108498 109127 D lipoprotein 108498..109127 Haemophilus influenzae 86-028NP 3429458 YP_247768.1 CDS NTHI0121 NC_007146.2 109131 109871 D hypothetical protein 109131..109871 Haemophilus influenzae 86-028NP 3429459 YP_247769.1 CDS NTHI0122 NC_007146.2 109850 110608 D hypothetical protein 109850..110608 Haemophilus influenzae 86-028NP 3429460 YP_247770.1 CDS NTHI0123 NC_007146.2 110624 111130 D hypothetical protein 110624..111130 Haemophilus influenzae 86-028NP 3429461 YP_247771.1 CDS NTHI0125 NC_007146.2 111127 113376 D hypothetical protein 111127..113376 Haemophilus influenzae 86-028NP 3429462 YP_247772.1 CDS NTHI0126 NC_007146.2 113695 114381 D hypothetical protein 113695..114381 Haemophilus influenzae 86-028NP 3429463 YP_247773.1 CDS NTHI0127 NC_007146.2 114512 114862 D hypothetical protein 114512..114862 Haemophilus influenzae 86-028NP 3429464 YP_247774.1 CDS NTHI0128 NC_007146.2 115131 115532 D hypothetical protein 115131..115532 Haemophilus influenzae 86-028NP 3429465 YP_247775.1 CDS NTHI0129 NC_007146.2 115552 115923 D hypothetical protein 115552..115923 Haemophilus influenzae 86-028NP 3429466 YP_247776.1 CDS NTHI0130 NC_007146.2 115935 116579 D hypothetical protein 115935..116579 Haemophilus influenzae 86-028NP 3429467 YP_247777.1 CDS NTHI0131 NC_007146.2 116579 117448 D hypothetical protein 116579..117448 Haemophilus influenzae 86-028NP 3429468 YP_247778.1 CDS NTHI0132 NC_007146.2 117459 118859 D hypothetical protein 117459..118859 Haemophilus influenzae 86-028NP 3429469 YP_247779.1 CDS NTHI0133 NC_007146.2 118869 119276 D lipoprotein 118869..119276 Haemophilus influenzae 86-028NP 3429470 YP_247780.1 CDS NTHI0134 NC_007146.2 119292 122162 D hypothetical protein 119292..122162 Haemophilus influenzae 86-028NP 3429471 YP_247781.1 CDS NTHI0135 NC_007146.2 122170 122577 D hypothetical protein 122170..122577 Haemophilus influenzae 86-028NP 3429472 YP_247782.1 CDS NTHI0136 NC_007146.2 122587 122910 D hypothetical protein 122587..122910 Haemophilus influenzae 86-028NP 3429473 YP_247783.1 CDS NTHI0137 NC_007146.2 122919 124412 D hypothetical protein 122919..124412 Haemophilus influenzae 86-028NP 3429474 YP_247784.1 CDS NTHI0139 NC_007146.2 124468 124797 R hypothetical protein complement(124468..124797) Haemophilus influenzae 86-028NP 3429475 YP_247785.1 CDS tnpA NC_007146.2 124955 127960 R Similar to: TNP3_ECOLI; transposon Tn3 transposase complement(124955..127960) Haemophilus influenzae 86-028NP 3429476 YP_247786.1 CDS NTHI0140 NC_007146.2 126925 127041 D hypothetical protein 126925..127041 Haemophilus influenzae 86-028NP 3429477 YP_247787.2 CDS tnpR NC_007146.2 128088 128681 D Similar to: TNR3_ECOLI; transposon Tn3 resolvase 128088..128681 Haemophilus influenzae 86-028NP 3429478 YP_001621483.1 CDS NTHI2055 NC_007146.2 128729 129589 D beta-lactamase TEM 128729..129589 Haemophilus influenzae 86-028NP 5815435 YP_247788.1 CDS NTHI0143 NC_007146.2 129813 129992 D hypothetical protein 129813..129992 Haemophilus influenzae 86-028NP 3429479 YP_247789.1 CDS NTHI0144 NC_007146.2 130037 130444 R hypothetical protein complement(130037..130444) Haemophilus influenzae 86-028NP 3429480 YP_247790.1 CDS NTHI0145 NC_007146.2 130460 132460 R hypothetical protein complement(130460..132460) Haemophilus influenzae 86-028NP 3429481 YP_247791.1 CDS NTHI0146 NC_007146.2 132475 133416 R hypothetical protein complement(132475..133416) Haemophilus influenzae 86-028NP 3429482 YP_247792.1 CDS NTHI0147 NC_007146.2 133413 133856 R hypothetical protein complement(133413..133856) Haemophilus influenzae 86-028NP 3429483 YP_247793.1 CDS NTHI0148 NC_007146.2 134168 134587 D hypothetical protein 134168..134587 Haemophilus influenzae 86-028NP 3429484 YP_247794.1 CDS NTHI0149 NC_007146.2 134672 134905 D hypothetical protein 134672..134905 Haemophilus influenzae 86-028NP 3429485 YP_247795.1 CDS NTHI0150 NC_007146.2 134908 135156 D hypothetical protein 134908..135156 Haemophilus influenzae 86-028NP 3429486 YP_247796.1 CDS NTHI0151 NC_007146.2 135160 135318 D hypothetical protein 135160..135318 Haemophilus influenzae 86-028NP 3429487 YP_247797.1 CDS traC NC_007146.2 135449 136402 D Similar to: TRC4_ECOLI; antirestriction protein 135449..136402 Haemophilus influenzae 86-028NP 3429488 YP_247798.1 CDS NTHI0153 NC_007146.2 136506 137267 D type I restriction enzyme M subunit 136506..137267 Haemophilus influenzae 86-028NP 3429489 YP_247799.1 CDS NTHI0154 NC_007146.2 137493 138059 D hypothetical protein 137493..138059 Haemophilus influenzae 86-028NP 3429490 YP_247800.1 CDS NTHI0155 NC_007146.2 138099 138473 D hypothetical protein 138099..138473 Haemophilus influenzae 86-028NP 3429491 YP_247801.1 CDS NTHI0156 NC_007146.2 138463 139140 D hypothetical protein 138463..139140 Haemophilus influenzae 86-028NP 3429492 YP_247802.1 CDS NTHI0157 NC_007146.2 139118 139735 D hypothetical protein 139118..139735 Haemophilus influenzae 86-028NP 3429493 YP_247803.1 CDS NTHI0158 NC_007146.2 139999 140598 R resolvase/integrase-like protein complement(139999..140598) Haemophilus influenzae 86-028NP 3429494 YP_247804.1 CDS NTHI0159 NC_007146.2 140613 140804 R hypothetical protein complement(140613..140804) Haemophilus influenzae 86-028NP 3429495 YP_247805.1 CDS NTHI0160 NC_007146.2 141273 141527 R hypothetical protein complement(141273..141527) Haemophilus influenzae 86-028NP 3429496 YP_247806.1 CDS NTHI0161 NC_007146.2 142718 143431 D hypothetical protein 142718..143431 Haemophilus influenzae 86-028NP 3429497 YP_247807.1 CDS NTHI0162 NC_007146.2 144151 145404 D hypothetical protein 144151..145404 Haemophilus influenzae 86-028NP 3429498 YP_247808.1 CDS NTHI0163 NC_007146.2 145547 147463 D hypothetical protein 145547..147463 Haemophilus influenzae 86-028NP 3429499 YP_247809.1 CDS NTHI0164 NC_007146.2 147524 148366 D Similar to: XERC_PSESX; site-specific recombinase 147524..148366 Haemophilus influenzae 86-028NP 3429500 YP_247810.1 CDS thrC NC_007146.2 149016 150293 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(149016..150293) Haemophilus influenzae 86-028NP 3429502 YP_247811.1 CDS thrB NC_007146.2 150336 151280 R HK; catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase complement(150336..151280) Haemophilus influenzae 86-028NP 3429503 YP_247812.1 CDS thrA NC_007146.2 151293 153740 R bifunctional protein including aspartokinase, homoserine dehydrogenase; AK-HD; multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I complement(151293..153740) Haemophilus influenzae 86-028NP 3429504 YP_247813.1 CDS NTHI0168 NC_007146.2 154064 154777 D Similar to: HI0090, Y090_HAEIN; hypothetical protein 154064..154777 Haemophilus influenzae 86-028NP 3429505 YP_247814.1 CDS grk NC_007146.2 154817 155953 R Similar to: HI0091, GRK_HAEIN; glycerate kinase complement(154817..155953) Haemophilus influenzae 86-028NP 3429506 YP_247815.1 CDS NTHI0171 NC_007146.2 155962 157221 R Similar to: HI0092, Y092_HAEIN; hypothetical protein complement(155962..157221) Haemophilus influenzae 86-028NP 3429507 YP_247816.1 CDS NTHI0172 NC_007146.2 157343 158449 R Similar to: HI0093, Y093_HAEIN; hypothetical protein complement(157343..158449) Haemophilus influenzae 86-028NP 3429508 YP_247817.1 CDS NTHI0173 NC_007146.2 158651 158971 R Similar to: HI0094, Y094_HAEIN; hypothetical protein complement(158651..158971) Haemophilus influenzae 86-028NP 3429509 YP_247818.1 CDS NTHI0175 NC_007146.2 159322 160077 R Similar to: HI0095, Y095_HAEIN; hypothetical protein complement(159322..160077) Haemophilus influenzae 86-028NP 3429511 YP_247819.1 CDS NTHI0176 NC_007146.2 160278 160559 D Similar to: HI0096, Y096_HAEIN; hypothetical protein 160278..160559 Haemophilus influenzae 86-028NP 3429512 YP_247820.1 CDS hitA NC_007146.2 160711 161709 D Major ferric iron binding protein; Iron-regulated 40 kDa protein; MIRP; Fe(3+)-binding protein; Similar to: HI0097, FBPA_HAEIN; iron-utilization periplasmic protein hFbpA 160711..161709 Haemophilus influenzae 86-028NP 3429513 YP_247821.1 CDS hitB NC_007146.2 161827 163347 D Similar to: HI0098, FBB2_HAEIN; iron ABC transporter permease 161827..163347 Haemophilus influenzae 86-028NP 3429514 YP_247822.1 CDS hitC NC_007146.2 163349 164404 D Similar to: HI0099, FBC2_HAEIN; iron-utilization ATP-binding protein hFbpC 163349..164404 Haemophilus influenzae 86-028NP 3429515 YP_247823.1 CDS NTHI0181 NC_007146.2 164439 165119 R Similar to: HI0100, Y100_HAEIN; D-alanyl-D-alanine carboxypeptidase complement(164439..165119) Haemophilus influenzae 86-028NP 3429516 YP_247824.1 CDS dapE NC_007146.2 165121 166254 R SDAP; dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica; succinyl-diaminopimelate desuccinylase complement(165121..166254) Haemophilus influenzae 86-028NP 3429517 YP_247825.1 CDS NTHI0184 NC_007146.2 166282 166626 R Similar to: HI0103, YFFB_HAEIN; hypothetical protein complement(166282..166626) Haemophilus influenzae 86-028NP 3429518 YP_247826.1 CDS htpG NC_007146.2 166705 168600 R Heat shock protein htpG; High temperature protein G; molecular chaperone; heat shock protein 90 complement(166705..168600) Haemophilus influenzae 86-028NP 3429519 YP_247827.1 CDS NTHI0186 NC_007146.2 168812 169651 D Similar to: HI0105, YBGI_HAEIN; NIF3-like protein 168812..169651 Haemophilus influenzae 86-028NP 3429520 YP_247828.1 CDS hsdM1 NC_007146.2 169825 172197 D type I restriction-modification system, methyltransferase subunit 169825..172197 Haemophilus influenzae 86-028NP 3429521 YP_247829.1 CDS NTHI0190 NC_007146.2 172380 173789 D transcription regulator 172380..173789 Haemophilus influenzae 86-028NP 3429522 YP_247830.1 CDS hsdS1 NC_007146.2 173961 175211 D type I site-specific restriction-modification system, S subunit 173961..175211 Haemophilus influenzae 86-028NP 3429523 YP_247831.1 CDS hsdR1 NC_007146.2 175311 178337 D type I site-specific restriction-modification system, R subunit 175311..178337 Haemophilus influenzae 86-028NP 3429524 YP_247832.1 CDS ffh NC_007146.2 178562 179941 R Fifty-four homolog; Similar to: HI0106, SR54_HAEIN; Signal recognition particle protein complement(178562..179941) Haemophilus influenzae 86-028NP 3429525 YP_247833.1 CDS corB NC_007146.2 180192 181484 D Similar to: HI0107, YFJD_HAEIN; Mg2+ and Co2+ transporter 180192..181484 Haemophilus influenzae 86-028NP 3429526 YP_247834.1 CDS NTHI0197 NC_007146.2 181505 182383 D Similar to: HI0108, YJJP_ECOLI; hypothetical protein 181505..182383 Haemophilus influenzae 86-028NP 3429527 YP_247835.1 CDS NTHI0198 NC_007146.2 182385 182864 D Similar to: HI0108, YJJP_HAEIN; hypothetical protein 182385..182864 Haemophilus influenzae 86-028NP 3429528 YP_247836.1 CDS NTHI0199 NC_007146.2 182954 183295 R Similar to: HI0109, Y109_HAEIN; hypothetical protein complement(182954..183295) Haemophilus influenzae 86-028NP 3429529 YP_247837.1 CDS serS NC_007146.2 183462 184751 D Serine--tRNA ligase; SerRS; catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 183462..184751 Haemophilus influenzae 86-028NP 3429530 YP_247838.1 CDS gst NC_007146.2 185086 185715 D Similar to: HI0111, GT_HAEIN; glutathione S-transferase 185086..185715 Haemophilus influenzae 86-028NP 3429531 YP_247839.1 CDS NTHI0201_1 NC_007146.2 185727 186023 R hypothetical protein complement(185727..186023) Haemophilus influenzae 86-028NP 3429532 YP_247840.1 CDS hemR NC_007146.2 186076 188313 D Similar to: HI0113, HXC1_HAEIN; hemin receptor 186076..188313 Haemophilus influenzae 86-028NP 3429533 YP_247841.1 CDS rlmL NC_007146.2 195361 197496 R catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase complement(195361..197496) Haemophilus influenzae 86-028NP 3429541 YP_247842.1 CDS mltA NC_007146.2 197889 198998 D murein hydrolase A; Mlt38; membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 197889..198998 Haemophilus influenzae 86-028NP 3429543 YP_247843.1 CDS NTHI0206 NC_007146.2 198998 199768 D homolog of dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; Similar to: HI0118, YGDL_HAEIN; hypothetical protein 198998..199768 Haemophilus influenzae 86-028NP 3429544 YP_247844.1 CDS znuA NC_007146.2 199946 200947 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic component 199946..200947 Haemophilus influenzae 86-028NP 3429545 YP_247845.1 CDS NTHI0209 NC_007146.2 200997 201503 R Similar to: HI0120, Y120_HAEIN; hypothetical protein complement(200997..201503) Haemophilus influenzae 86-028NP 3429546 YP_247846.1 CDS mpl NC_007146.2 201616 202974 R Murein peptide ligase; Similar to: HI0121, MPL_HAEIN; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase complement(201616..202974) Haemophilus influenzae 86-028NP 3429547 YP_247847.1 CDS metC NC_007146.2 203359 204546 R CBL; beta-cystathionase; cysteine lyase; catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase complement(203359..204546) Haemophilus influenzae 86-028NP 3429548 YP_247848.1 CDS tsaA NC_007146.2 204677 205285 D Similar to: TSAA_BUCAP; peroxiredoxin 204677..205285 Haemophilus influenzae 86-028NP 3429549 YP_247849.1 CDS pgsA NC_007146.2 205386 205943 D phosphatidylglycerophosphate synthase; PGP synthase; Similar to: HI0123, PGSA_HAEIN; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 205386..205943 Haemophilus influenzae 86-028NP 3429550 YP_247850.1 CDS ppa NC_007146.2 206507 207037 R pyrophosphate phospho-hydrolase; PPase; catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(206507..207037) Haemophilus influenzae 86-028NP 3429554 YP_247851.1 CDS NTHI0215 NC_007146.2 207271 208587 D Similar to: HI0125, YJCD_HAEIN; hypothetical protein 207271..208587 Haemophilus influenzae 86-028NP 3429555 YP_247852.1 CDS udk NC_007146.2 208810 209451 D uridine monophosphokinase; cytidine monophosphokinase; functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 208810..209451 Haemophilus influenzae 86-028NP 3429556 YP_247853.1 CDS dcd NC_007146.2 209460 210047 D dCTP deaminase; Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 209460..210047 Haemophilus influenzae 86-028NP 3429557 YP_247854.1 CDS NTHI0220 NC_007146.2 210051 211226 D Similar to: HI0134, Y134_HAEIN; hypothetical protein 210051..211226 Haemophilus influenzae 86-028NP 3429558 YP_247855.1 CDS NTHI0221 NC_007146.2 211226 212434 D Similar to: HI0135, SOTB_HAEIN; sugar efflux transporter 211226..212434 Haemophilus influenzae 86-028NP 3429559 YP_247856.1 CDS engA NC_007146.2 212495 214009 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(212495..214009) Haemophilus influenzae 86-028NP 3429560 YP_247857.1 CDS dnaQ NC_007146.2 214691 215458 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(214691..215458) Haemophilus influenzae 86-028NP 3429563 YP_247858.1 CDS rnhA NC_007146.2 215519 215983 D RNase HI; An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 215519..215983 Haemophilus influenzae 86-028NP 3429564 YP_247859.1 CDS ompP2 NC_007146.2 216249 217346 D OMP P2; Similar to: HI0139, OP27_HAEIN; outer membrane protein P2 216249..217346 Haemophilus influenzae 86-028NP 3429565 YP_247860.1 CDS nagA NC_007146.2 217543 218688 R GlcNAc 6-P deacetylase; catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(217543..218688) Haemophilus influenzae 86-028NP 3429566 YP_247861.1 CDS nagB NC_007146.2 218825 219637 R glucosamine-6-phosphate isomerase; GNPDA; GlcN6P deaminase; catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(218825..219637) Haemophilus influenzae 86-028NP 3429567 YP_247862.1 CDS nanA NC_007146.2 219973 220854 R N-acetylneuraminic acid aldolase; N-acetylneuraminate pyruvate-lyase; sialic acid lyase; sialate lyase; sialic acid aldolase; catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(219973..220854) Haemophilus influenzae 86-028NP 3429568 YP_247863.1 CDS NTHI0229 NC_007146.2 220865 221731 R Similar to: HI0143, Y143_HAEIN; HTH-type transcriptional regulator complement(220865..221731) Haemophilus influenzae 86-028NP 3429569 YP_247864.1 CDS nanK NC_007146.2 221724 222626 R ManNAc kinase; catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(221724..222626) Haemophilus influenzae 86-028NP 3429570 YP_247865.1 CDS nanE NC_007146.2 222671 223357 R ManNAc-6-P epimerase; Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(222671..223357) Haemophilus influenzae 86-028NP 3429571 YP_247866.1 CDS NTHI0232 NC_007146.2 223707 224696 D Similar to: HI0146, Y146_HAEIN; sialic acid transporter, TRAP-type C4-dicarboxylate transport system, periplasmic component 223707..224696 Haemophilus influenzae 86-028NP 3429572 YP_247867.1 CDS siaT NC_007146.2 224761 226611 D Similar to: HI0147, Y147_HAEIN; hypothetical protein 224761..226611 Haemophilus influenzae 86-028NP 3429573 YP_247868.1 CDS NTHI0235 NC_007146.2 226775 227914 D Similar to: HI0148, YJHT_HAEIN; N-acetylneuraminic acid mutarotase 226775..227914 Haemophilus influenzae 86-028NP 3429574 YP_247869.1 CDS NTHI0236 NC_007146.2 228076 228510 D Similar to: HI0149; protein-S-isoprenylcysteine methyltransferase 228076..228510 Haemophilus influenzae 86-028NP 3429575 YP_247870.1 CDS hflC NC_007146.2 228552 229439 R Similar to: HI0150, HFLC_HAEIN; hypothetical protein complement(228552..229439) Haemophilus influenzae 86-028NP 3429576 YP_247871.1 CDS hflK NC_007146.2 229439 230671 R Similar to: HI0151, HFLK_HAEIN; HflK complement(229439..230671) Haemophilus influenzae 86-028NP 3429577 YP_247872.1 CDS NTHI0240 NC_007146.2 230781 231488 R Similar to: HI0152, Y152_HAEIN; 4'-phosphopantetheinyl transferase complement(230781..231488) Haemophilus influenzae 86-028NP 3429578 YP_247873.1 CDS dcuB2 NC_007146.2 231548 232879 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(231548..232879) Haemophilus influenzae 86-028NP 3429579 YP_247874.1 CDS acpP NC_007146.2 233083 233313 R ACP; carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(233083..233313) Haemophilus influenzae 86-028NP 3429580 YP_247875.1 CDS fabG NC_007146.2 233573 234301 R 3-ketoacyl-acyl carrier protein reductase; catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(233573..234301) Haemophilus influenzae 86-028NP 3429581 YP_247876.1 CDS fabD NC_007146.2 234318 235256 R MCT; Similar to: HI0156, FABD_HAEIN; ACP S-malonyltransferase complement(234318..235256) Haemophilus influenzae 86-028NP 3429582 YP_247877.1 CDS fabH NC_007146.2 235756 236706 R beta-ketoacyl-ACP synthase III; KAS III; FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase complement(235756..236706) Haemophilus influenzae 86-028NP 3429583 YP_247878.1 CDS rpmF NC_007146.2 236892 237062 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(236892..237062) Haemophilus influenzae 86-028NP 3429584 YP_247879.1 CDS NTHI0249 NC_007146.2 237085 237609 R Similar to: HI0159, YCED_HAEIN; hypothetical protein complement(237085..237609) Haemophilus influenzae 86-028NP 3429585 YP_247880.1 CDS psd NC_007146.2 237766 238638 D phosphatidylserine decarboxylase alpha chain; phosphatidylserine decarboxylase beta chain; catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 237766..238638 Haemophilus influenzae 86-028NP 3429586 YP_247881.1 CDS gor NC_007146.2 238747 240117 R GR; GRase; catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase complement(238747..240117) Haemophilus influenzae 86-028NP 3429587 YP_247882.1 CDS NTHI0252 NC_007146.2 240333 240932 R Similar to: HI0162, YAJG_HAEIN; lipoprotein complement(240333..240932) Haemophilus influenzae 86-028NP 3429588 YP_247883.1 CDS nqrA NC_007146.2 241628 242971 D Na(+)-translocating NQR subunit A; Na(+)-NQR subunit A; NQR complex subunit A; NQR-1 subunit A; uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A 241628..242971 Haemophilus influenzae 86-028NP 3429590 YP_247884.1 CDS nqrB NC_007146.2 242974 244209 D Na(+)-translocating NQR subunit B; Na(+)-NQR subunit B; NQR complex subunit B; NQR-1 subunit B; uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B 242974..244209 Haemophilus influenzae 86-028NP 3429591 YP_247885.1 CDS nqrC NC_007146.2 244202 244936 D Na(+)-translocating NQR subunit C; Na(+)-NQR subunit C; NQR complex subunit C; NQR-1 subunit C; uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C 244202..244936 Haemophilus influenzae 86-028NP 3429592 YP_247886.1 CDS nqrD NC_007146.2 244936 245562 D Na(+)-translocating NQR subunit D; Na(+)-NQR subunit D; NQR complex subunit D; NQR-1 subunit D; Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D 244936..245562 Haemophilus influenzae 86-028NP 3429593 YP_247887.1 CDS nqrE NC_007146.2 245566 246162 D Na(+)-translocating NQR subunit E; Na(+)-NQR subunit E; NQR complex subunit E; NQR-1 subunit E; Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Na(+)-translocating NADH-quinone reductase subunit E 245566..246162 Haemophilus influenzae 86-028NP 3429594 YP_247888.1 CDS nqrF NC_007146.2 246175 247410 D Na(+)-translocating NQR subunit F; Na(+)-NQR subunit F; NQR complex subunit F; NQR-1 subunit F; uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F 246175..247410 Haemophilus influenzae 86-028NP 3429595 YP_247889.1 CDS apbE NC_007146.2 247554 248594 D Similar to: HI0172, APBE_HAEIN; thiamine biosynthesis lipoprotein ApbE 247554..248594 Haemophilus influenzae 86-028NP 3429596 YP_247890.1 CDS NTHI0261 NC_007146.2 248597 248857 D Similar to: HI0173, Y173_HAEIN; hypothetical protein 248597..248857 Haemophilus influenzae 86-028NP 3429597 YP_247891.1 CDS mnmA NC_007146.2 248932 250125 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 248932..250125 Haemophilus influenzae 86-028NP 3429598 YP_247892.1 CDS NTHI0263 NC_007146.2 250169 250903 R Similar to: HI0175, YFIH_HAEIN; hypothetical protein complement(250169..250903) Haemophilus influenzae 86-028NP 3429599 YP_247893.1 CDS rluD NC_007146.2 250905 251879 R pseudouridylate synthase; Uracil hydrolyase; responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D complement(250905..251879) Haemophilus influenzae 86-028NP 3429600 YP_247894.1 CDS NTHI0266 NC_007146.2 251987 252775 D Similar to: HI0177, YFIO_HAEIN; hypothetical protein 251987..252775 Haemophilus influenzae 86-028NP 3429601 YP_247895.1 CDS NTHI0267 NC_007146.2 252854 253336 R Similar to: HI0178, Y178_HAEIN; hypothetical protein complement(252854..253336) Haemophilus influenzae 86-028NP 3429602 YP_247896.1 CDS pflA NC_007146.2 253368 254108 R PFL-activating enzyme; activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(253368..254108) Haemophilus influenzae 86-028NP 3429603 YP_247897.1 CDS pflB NC_007146.2 254233 256551 R pyruvate formate-lyase; Similar to: HI0180, PFLB_HAEIN; formate acetyltransferase complement(254233..256551) Haemophilus influenzae 86-028NP 3429604 YP_247898.1 CDS focA NC_007146.2 256583 257437 R Similar to: HI0181, FOCA_HAEIN; formate transporter complement(256583..257437) Haemophilus influenzae 86-028NP 3429605 YP_247899.1 CDS NTHI0273 NC_007146.2 257942 258856 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 257942..258856 Haemophilus influenzae 86-028NP 3429606 YP_247900.1 CDS NTHI0274 NC_007146.2 259035 260480 D Similar to: HI0183, YAAJ_HAEIN; Na+/alanine symporter 259035..260480 Haemophilus influenzae 86-028NP 3429607 YP_247901.1 CDS NTHI0275 NC_007146.2 260665 261492 R Similar to: HI0184, YAIM_HAEIN; esterase complement(260665..261492) Haemophilus influenzae 86-028NP 3429608 YP_247902.1 CDS NTHI0278 NC_007146.2 262760 263167 D Similar to: HI0186, Y186_HAEIN; HTH-type transcriptional regulator 262760..263167 Haemophilus influenzae 86-028NP 3429610 YP_247903.1 CDS tatA NC_007146.2 263325 263612 D Similar to: TATA_HAEIN; Sec-independent protein translocase protein TatA/E 263325..263612 Haemophilus influenzae 86-028NP 3429611 YP_247904.1 CDS tatB NC_007146.2 263616 264176 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 263616..264176 Haemophilus influenzae 86-028NP 3429612 YP_247905.1 CDS tatC NC_007146.2 264186 264956 D Similar to: HI0188, TATC_HAEIN; Sec-independent protein translocase protein TatC 264186..264956 Haemophilus influenzae 86-028NP 3429613 YP_247906.1 CDS gdhA NC_007146.2 265317 266666 D NADP-GDH; converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 265317..266666 Haemophilus influenzae 86-028NP 3429614 YP_247907.1 CDS fur NC_007146.2 266774 267214 R ferric uptake regulator; Similar to: HI0190, FUR_HAEIN; ferric uptake regulation protein complement(266774..267214) Haemophilus influenzae 86-028NP 3429615 YP_247908.1 CDS fldA NC_007146.2 267243 267767 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(267243..267767) Haemophilus influenzae 86-028NP 3429616 YP_247909.1 CDS NTHI0286 NC_007146.2 267864 268727 R Similar to: HI0193, Y193_HAEIN; esterase complement(267864..268727) Haemophilus influenzae 86-028NP 3429617 YP_247910.1 CDS seqA NC_007146.2 268717 269322 D negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 268717..269322 Haemophilus influenzae 86-028NP 3429618 YP_247911.1 CDS menE NC_007146.2 269325 270683 D OSB-CoA synthetase; O-succinylbenzoyl-CoA synthetase; Similar to: HI0194, MENE_HAEIN; O-succinylbenzoic acid--CoA ligase 269325..270683 Haemophilus influenzae 86-028NP 3429619 YP_247912.1 CDS NTHI0291 NC_007146.2 270711 274049 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 270711..274049 Haemophilus influenzae 86-028NP 3429620 YP_247913.1 CDS aroC NC_007146.2 274059 275132 D 5-enolpyruvylshikimate-3-phosphate phospholyase; catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 274059..275132 Haemophilus influenzae 86-028NP 3429621 YP_247914.1 CDS mepA NC_007146.2 275305 276165 D D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 275305..276165 Haemophilus influenzae 86-028NP 3429622 YP_247915.1 CDS NTHI0295 NC_007146.2 276183 276950 D Similar to: HI0198, YFCA_HAEIN; hypothetical protein 276183..276950 Haemophilus influenzae 86-028NP 3429623 YP_247916.1 CDS msbB NC_007146.2 276997 277953 D Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 276997..277953 Haemophilus influenzae 86-028NP 3429624 YP_247917.1 CDS selD NC_007146.2 278080 279051 D selenophosphate synthetase; selenium donor protein; catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 278080..279051 Haemophilus influenzae 86-028NP 3429625 YP_247918.1 CDS rplS NC_007146.2 279160 279510 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(279160..279510) Haemophilus influenzae 86-028NP 3429626 YP_247919.1 CDS trmD NC_007146.2 279547 280287 R M1G-methyltransferase; tRNA [GM37] methyltransferase; methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(279547..280287) Haemophilus influenzae 86-028NP 3429627 YP_247920.1 CDS rimM NC_007146.2 280325 280852 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(280325..280852) Haemophilus influenzae 86-028NP 3429628 YP_247921.1 CDS rpsP NC_007146.2 280897 281145 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(280897..281145) Haemophilus influenzae 86-028NP 3429629 YP_247922.1 CDS NTHI0302 NC_007146.2 281425 282210 D Similar to: HI0205, Y205_HAEIN; hypothetical protein 281425..282210 Haemophilus influenzae 86-028NP 3429630 YP_247923.1 CDS nadN NC_007146.2 282233 284044 D 5'-nucleotidase; Similar to: HI0206, 5NTD_HAEIN; NAD nucleotidase 282233..284044 Haemophilus influenzae 86-028NP 3429631 YP_247924.1 CDS aroK NC_007146.2 284329 284871 D SK; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 284329..284871 Haemophilus influenzae 86-028NP 3429632 YP_247925.1 CDS aroB NC_007146.2 284891 285979 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 284891..285979 Haemophilus influenzae 86-028NP 3429633 YP_247926.1 CDS dam NC_007146.2 285981 286841 D deoxyadenosyl-methyltransferase; DNA adenine methyltransferase; M.HindIV; Similar to: HI0209, DMA_HAEIN; DNA adenine methylase 285981..286841 Haemophilus influenzae 86-028NP 3429634 YP_247927.1 CDS NTHI0307_1 NC_007146.2 287806 287913 D hypothetical protein 287806..287913 Haemophilus influenzae 86-028NP 3429635 YP_247928.1 CDS pgpB NC_007146.2 287932 288657 R Similar to: HI0211, PGPB_HAEIN; phosphatidylglycerophosphatase B complement(287932..288657) Haemophilus influenzae 86-028NP 3429636 YP_247929.1 CDS ribA NC_007146.2 288703 289377 D catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 288703..289377 Haemophilus influenzae 86-028NP 3429637 YP_247930.1 CDS NTHI0310 NC_007146.2 289693 291237 R Similar to: HI0213, Y213_HAEIN; ABC-type oligopeptide transport system, periplasmic component complement(289693..291237) Haemophilus influenzae 86-028NP 3429638 YP_247931.1 CDS NTHI0311 NC_007146.2 291230 291592 R hypothetical protein complement(291230..291592) Haemophilus influenzae 86-028NP 3429639 YP_247932.1 CDS prlC NC_007146.2 291711 293756 D Similar to: HI0214, OPDA_HAEIN; oligopeptidase A 291711..293756 Haemophilus influenzae 86-028NP 3429640 YP_247933.1 CDS hsdM2 NC_007146.2 293988 295532 D M protein; Similar to: HI1287, T1MP_ECOLI; type I restriction-modification system methyltransferase subunit 293988..295532 Haemophilus influenzae 86-028NP 3429641 YP_247934.1 CDS hsdS2 NC_007146.2 295617 296789 D S protein; Similar to: HI0216, T1SI_HAEIN; type I restriction-modification system specificity protein 295617..296789 Haemophilus influenzae 86-028NP 3429642 YP_247935.1 CDS prrC NC_007146.2 296791 297945 D Similar to: PRRC_ECOLI; anticodon nuclease 296791..297945 Haemophilus influenzae 86-028NP 3429643 YP_247936.1 CDS NTHI0317 NC_007146.2 297948 298946 D DNA binding protein 297948..298946 Haemophilus influenzae 86-028NP 3429644 YP_247937.1 CDS hsdR2 NC_007146.2 298957 302040 D R protein; Similar to: T1R1_ECOLI; type I restriction-modification system 298957..302040 Haemophilus influenzae 86-028NP 3429645 YP_247938.1 CDS NTHI0319 NC_007146.2 302187 302816 R Similar to: HI0219, YKGB_HAEIN; hypothetical protein complement(302187..302816) Haemophilus influenzae 86-028NP 3429646 YP_247939.1 CDS arcB NC_007146.2 303030 304871 R Similar to: HI1651, ARCB_HAEIN; aerobic respiration control sensor protein ArcB complement(303030..304871) Haemophilus influenzae 86-028NP 3429647 YP_247940.1 CDS NTHI0322 NC_007146.2 304940 305584 R Similar to: HI0220.2, Y22A_HAEIN; uracil-DNA glycosylase complement(304940..305584) Haemophilus influenzae 86-028NP 3429648 YP_247941.1 CDS birA NC_007146.2 311636 312544 R Biotin--protein ligase; catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase complement(311636..312544) Haemophilus influenzae 86-028NP 3429653 YP_247942.1 CDS guaB NC_007146.2 312671 314137 D IMP dehydrogenase; IMPDH; IMPD; catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 312671..314137 Haemophilus influenzae 86-028NP 3429654 YP_247943.1 CDS guaA NC_007146.2 314247 315818 D glutamine amidotransferase; GMP synthetase; contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 314247..315818 Haemophilus influenzae 86-028NP 3429655 YP_247944.1 CDS NTHI0327 NC_007146.2 315880 316782 R Similar to: HI0223, Y223_HAEIN; hypothetical protein complement(315880..316782) Haemophilus influenzae 86-028NP 3429656 YP_247945.1 CDS NTHI0328 NC_007146.2 316845 317351 D Similar to: HI0224, Y224_HAEIN; transcriptional regulator 316845..317351 Haemophilus influenzae 86-028NP 3429657 YP_247946.1 CDS nhaA NC_007146.2 317390 318592 R Sodium/proton antiporter 1; exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter complement(317390..318592) Haemophilus influenzae 86-028NP 3429658 YP_247947.1 CDS brnQ NC_007146.2 318780 320090 D branched-chain amino acid uptake carrier; Similar to: HI0226, BRNQ_HAEIN; branched chain amino acid ABC transporter carrier protein 318780..320090 Haemophilus influenzae 86-028NP 3429659 YP_247948.1 CDS NTHI0332 NC_007146.2 320198 320665 R Similar to: HI0227, YHCH_HAEIN; hypothetical protein complement(320198..320665) Haemophilus influenzae 86-028NP 3429660 YP_247949.1 CDS NTHI0333 NC_007146.2 320692 321138 R Similar to: HI0228, Y228_HAEIN; hypothetical protein complement(320692..321138) Haemophilus influenzae 86-028NP 3429661 YP_247950.1 CDS pnp NC_007146.2 321411 323540 D polynucleotide phosphorylase; PNPase; Similar to: HI0229, PNP_HAEIN; polynucleotide phosphorylase 321411..323540 Haemophilus influenzae 86-028NP 3429662 YP_247951.1 CDS nlpL NC_007146.2 323622 324566 D lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 323622..324566 Haemophilus influenzae 86-028NP 3429663 YP_247952.1 CDS deaD NC_007146.2 324686 326527 D ATP-dependent RNA helicase DeaD homolog; Similar to: HI0231, DEAD_HAEIN; cold-shock DEAD-box protein A-like protein 324686..326527 Haemophilus influenzae 86-028NP 3429664 YP_247953.1 CDS NTHI0338 NC_007146.2 326705 328093 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 326705..328093 Haemophilus influenzae 86-028NP 3429665 YP_247954.1 CDS NTHI0339 NC_007146.2 328098 328250 D Similar to: HI0233; hypothetical protein 328098..328250 Haemophilus influenzae 86-028NP 3429666 YP_247955.1 CDS NTHI0340 NC_007146.2 328384 328680 R Similar to: HI0234; hypothetical protein complement(328384..328680) Haemophilus influenzae 86-028NP 3429667 YP_247956.1 CDS NTHI0342 NC_007146.2 328737 328946 R Similar to: HI0235, YHDL_HAEIN; hypothetical protein complement(328737..328946) Haemophilus influenzae 86-028NP 3429668 YP_247957.1 CDS arsC NC_007146.2 329014 329364 R Similar to: HI0236, ARSC_HAEIN; arsenate reductase complement(329014..329364) Haemophilus influenzae 86-028NP 3429669 YP_247958.1 CDS perM NC_007146.2 329443 330492 D Similar to: PERM_HAEIN; permease PerM-like protein 329443..330492 Haemophilus influenzae 86-028NP 3429670 YP_247959.1 CDS secF NC_007146.2 330606 331583 R forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF complement(330606..331583) Haemophilus influenzae 86-028NP 3429671 YP_247960.1 CDS secD NC_007146.2 331591 333441 R part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD complement(331591..333441) Haemophilus influenzae 86-028NP 3429672 YP_247961.1 CDS yajC NC_007146.2 333511 333804 R member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC complement(333511..333804) Haemophilus influenzae 86-028NP 3429673 YP_247962.1 CDS NTHI0348 NC_007146.2 333912 334133 R Similar to: HI0242, Y242_HAEIN; redox protein, regulator of disulfide bond formation complement(333912..334133) Haemophilus influenzae 86-028NP 3429674 YP_247963.1 CDS NTHI0349 NC_007146.2 334130 334648 R Similar to: HI0243, Y243_HAEIN; hypothetical protein complement(334130..334648) Haemophilus influenzae 86-028NP 3429675 YP_247964.1 CDS tgt NC_007146.2 334713 335861 R tRNA-guanine transglycosylase; guanine insertion enzyme; Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(334713..335861) Haemophilus influenzae 86-028NP 3429676 YP_247965.1 CDS queA NC_007146.2 336206 337297 R queuosine biosynthesis protein QueA; Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase complement(336206..337297) Haemophilus influenzae 86-028NP 3429677 YP_247966.1 CDS NTHI0353 NC_007146.2 337421 337867 R Similar to: HI0246, Y246_HAEIN; hypothetical protein complement(337421..337867) Haemophilus influenzae 86-028NP 3429678 YP_247967.1 CDS hap NC_007146.2 338010 342188 R Similar to: HI0990, HAP_HAEIN; adhesion and penetration protein Hap complement(338010..342188) Haemophilus influenzae 86-028NP 3429679 YP_247968.1 CDS uvrA NC_007146.2 342506 345337 R UvrA; excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(342506..345337) Haemophilus influenzae 86-028NP 3429680 YP_247969.1 CDS ssb NC_007146.2 345490 345996 D SSB; Helix-destabilizing protein; binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 345490..345996 Haemophilus influenzae 86-028NP 3429681 YP_247970.1 CDS tonB NC_007146.2 346174 346968 R Similar to: HI0251, TONB_HAEIN; TonB complement(346174..346968) Haemophilus influenzae 86-028NP 3429682 YP_247971.1 CDS exbD NC_007146.2 346978 347421 R Similar to: HI0252, EXBD_HAEIN; biopolymer transport protein complement(346978..347421) Haemophilus influenzae 86-028NP 3429683 YP_247972.1 CDS exbB NC_007146.2 347425 347877 R Similar to: HI0253, EXBB_HAEIN; transport protein ExbB complement(347425..347877) Haemophilus influenzae 86-028NP 3429684 YP_247973.1 CDS bcp NC_007146.2 348046 348513 R bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase complement(348046..348513) Haemophilus influenzae 86-028NP 3429685 YP_247974.1 CDS dapA NC_007146.2 348614 349510 D DHDPS; catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 348614..349510 Haemophilus influenzae 86-028NP 3429686 YP_247975.1 CDS NTHI0363 NC_007146.2 349621 350250 D Similar to: HI0256, Y256_HAEIN; lipoprotein 349621..350250 Haemophilus influenzae 86-028NP 3429687 YP_247976.1 CDS NTHI0364 NC_007146.2 350440 350763 D Similar to: HI0257, YFIA_HAEIN; hypothetical protein 350440..350763 Haemophilus influenzae 86-028NP 3429688 YP_247977.1 CDS lgtC NC_007146.2 351477 352415 R Similar to: HI0258, Y258_HAEIN; UDP-galactose--lipooligosaccharide galactosyltransferase complement(351477..352415) Haemophilus influenzae 86-028NP 3429690 YP_247978.1 CDS orfM NC_007146.2 352483 353070 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase complement(352483..353070) Haemophilus influenzae 86-028NP 3429691 YP_247979.1 CDS kdkA NC_007146.2 353082 353807 R KDO kinase; catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position; 3-deoxy-D-manno-octulosonic-acid kinase complement(353082..353807) Haemophilus influenzae 86-028NP 3429692 YP_247980.1 CDS opsX NC_007146.2 353884 354927 D Similar to: HI0261, Y261_HAEIN; ADP-heptose--lipooligosaccharide heptosyltransferase I 353884..354927 Haemophilus influenzae 86-028NP 3429693 YP_247981.1 CDS hxuC NC_007146.2 355249 357378 D heme:hemopexin utilization protein C; Similar to: HI0262, HXC2_HAEIN; heme-hemopexin utilization protein C 355249..357378 Haemophilus influenzae 86-028NP 3429694 YP_247982.1 CDS hxuB NC_007146.2 357454 359151 D heme:hemopexin utilization protein B; Similar to: HI0263, HXB2_HAEIN; heme/hemopexin-binding protein B 357454..359151 Haemophilus influenzae 86-028NP 3429695 YP_247983.1 CDS hxuA NC_007146.2 359163 361928 D heme:hemopexin utilization protein A; Similar to: HI0264, HXA2_HAEIN; heme/hemopexin-binding protein A 359163..361928 Haemophilus influenzae 86-028NP 3429696 YP_247984.1 CDS folB NC_007146.2 362024 362380 R DHNA; Similar to: HI0265, FOLB_HAEIN; dihydroneopterin aldolase complement(362024..362380) Haemophilus influenzae 86-028NP 3429697 YP_247985.1 CDS NTHI0373 NC_007146.2 362463 363062 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 362463..363062 Haemophilus influenzae 86-028NP 3429698 YP_247986.1 CDS narQ NC_007146.2 363104 364807 D Similar to: HI0267, NARQ_HAEIN; nitrate/nitrite sensor protein NarQ 363104..364807 Haemophilus influenzae 86-028NP 3429699 YP_247987.1 CDS murB NC_007146.2 364817 365842 D UDP-N-acetylmuramate dehydrogenase; catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 364817..365842 Haemophilus influenzae 86-028NP 3429700 YP_247988.1 CDS rpoH NC_007146.2 365968 366813 D binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 365968..366813 Haemophilus influenzae 86-028NP 3429701 YP_247989.1 CDS djlA NC_007146.2 367280 368146 R functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein complement(367280..368146) Haemophilus influenzae 86-028NP 3429703 YP_247990.1 CDS pyrE NC_007146.2 368225 368866 R OPRT; OPRTase; involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(368225..368866) Haemophilus influenzae 86-028NP 3429704 YP_247991.1 CDS rph NC_007146.2 368890 369606 R RNase PH; tRNA nucleotidyltransferase; RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(368890..369606) Haemophilus influenzae 86-028NP 3429705 YP_247992.1 CDS gltX NC_007146.2 369907 371349 R glutamate--tRNA ligase; GluRS; Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(369907..371349) Haemophilus influenzae 86-028NP 3429707 YP_247993.1 CDS lpt6 NC_007146.2 372099 373754 D Similar to: HI0275, Y275_HAEIN; PE-tn-6--lipooligosaccharide phosphorylethanolamine transferase 372099..373754 Haemophilus influenzae 86-028NP 3429712 YP_247994.1 CDS rbn NC_007146.2 373772 374581 R RNase BN; RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN complement(373772..374581) Haemophilus influenzae 86-028NP 3429713 YP_247995.1 CDS NTHI0386 NC_007146.2 374578 375063 R Similar to: HI0277, Y277_HAEIN; hypothetical protein complement(374578..375063) Haemophilus influenzae 86-028NP 3429714 YP_247996.1 CDS NTHI0387 NC_007146.2 375066 375728 R Similar to: HI0278, YIIM_HAEIN; hypothetical protein complement(375066..375728) Haemophilus influenzae 86-028NP 3429715 YP_247997.2 CDS udp NC_007146.2 375964 376722 D UrdPase; UPase; catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 375964..376722 Haemophilus influenzae 86-028NP 3429716 YP_247998.1 CDS NTHI0390 NC_007146.2 376948 378264 R Similar to: HI0281, Y281_HAEIN; metabolite transport protein complement(376948..378264) Haemophilus influenzae 86-028NP 3429717 YP_247999.1 CDS NTHI0391 NC_007146.2 378320 379063 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase complement(378320..379063) Haemophilus influenzae 86-028NP 3429718 YP_248000.1 CDS menD NC_007146.2 379124 380830 R SHCHC synthase; alpha-ketoglutarate decarboxylase; KDC; SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(379124..380830) Haemophilus influenzae 86-028NP 3429719 YP_248001.1 CDS menF NC_007146.2 380846 382117 R isochorismate mutase; synthesizes isochorismate acid from chorismate; menaquinone-specific isochorismate synthase complement(380846..382117) Haemophilus influenzae 86-028NP 3429720 YP_248002.1 CDS aspC3 NC_007146.2 382274 383488 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 382274..383488 Haemophilus influenzae 86-028NP 3429721 YP_248003.1 CDS mtr NC_007146.2 383605 384861 D tryptophan permease; Similar to: HI0287, MTR_HAEIN; tryptophan-specific transport protein 383605..384861 Haemophilus influenzae 86-028NP 3429722 YP_248004.1 CDS sdaA NC_007146.2 384970 386337 R L-serine deaminase; SDH; L-SD; Similar to: HI0288, SDHL_HAEIN; L-serine dehydratase complement(384970..386337) Haemophilus influenzae 86-028NP 3429723 YP_248005.1 CDS sdaC NC_007146.2 386372 387610 R Similar to: HI0289, SDAC_HAEIN; serine transporter complement(386372..387610) Haemophilus influenzae 86-028NP 3429724 YP_248006.1 CDS NTHI0399 NC_007146.2 387833 390001 R Similar to: HI0290, Y290_HAEIN; cation-transporting ATPase complement(387833..390001) Haemophilus influenzae 86-028NP 3429725 YP_248007.1 CDS NTHI0403 NC_007146.2 390841 391227 D Similar to: HI0293, Y293_HAEIN; heavy metal dependent transcriptional regulator 390841..391227 Haemophilus influenzae 86-028NP 3429727 YP_248008.1 CDS metJ NC_007146.2 391241 391558 R Met regulon regulatory protein metJ; when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(391241..391558) Haemophilus influenzae 86-028NP 3429728 YP_248009.1 CDS rho NC_007146.2 391802 393064 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 391802..393064 Haemophilus influenzae 86-028NP 3429729 YP_248010.1 CDS pilD NC_007146.2 393118 393810 R Similar to: HI0296, LEP4_HAEIN; type 4 prepilin-like protein specific leader peptidase complement(393118..393810) Haemophilus influenzae 86-028NP 3429730 YP_248011.1 CDS pilC NC_007146.2 393807 395027 R Similar to: HI0297, HOFC_HAEIN; type IV pilin secretion protein complement(393807..395027) Haemophilus influenzae 86-028NP 3429731 YP_248012.1 CDS pilB NC_007146.2 395024 396418 R Similar to: HI0298, HOFB_HAEIN; type IV pilin secretion protein complement(395024..396418) Haemophilus influenzae 86-028NP 3429732 YP_248013.1 CDS pilA NC_007146.2 396415 396864 R Similar to: HI0299, PPDD_HAEIN; Type IV pilin subunit protein complement(396415..396864) Haemophilus influenzae 86-028NP 3429733 YP_248014.1 CDS ampD NC_007146.2 396979 397539 D Similar to: HI0300, AMPD_HAEIN; N-acetyl-anhydromuranmyl-L-alanine amidase 396979..397539 Haemophilus influenzae 86-028NP 3429734 YP_248015.1 CDS corC NC_007146.2 398161 399060 D Similar to: HI0301, CORC_HAEIN; magnesium and cobalt efflux protein CorC 398161..399060 Haemophilus influenzae 86-028NP 3429735 YP_248016.1 CDS lnt NC_007146.2 399044 400612 D ALP N-acyltransferase; Copper homeostasis protein CutE homolog; Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 399044..400612 Haemophilus influenzae 86-028NP 3429736 YP_248017.1 CDS NTHI0414 NC_007146.2 400662 401399 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 400662..401399 Haemophilus influenzae 86-028NP 3429737 YP_248018.1 CDS NTHI0415 NC_007146.2 401396 401956 D Similar to: HI0304, YQGE_HAEIN; hypothetical protein 401396..401956 Haemophilus influenzae 86-028NP 3429738 YP_248019.1 CDS ruvX NC_007146.2 401956 402375 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 401956..402375 Haemophilus influenzae 86-028NP 3429739 YP_248020.1 CDS NTHI0419 NC_007146.2 403545 404756 D Similar to: INTA_ECOLI; prophage CP4-57-like integrase 403545..404756 Haemophilus influenzae 86-028NP 3429741 YP_248021.1 CDS NTHI0420 NC_007146.2 404793 405227 R hypothetical protein complement(404793..405227) Haemophilus influenzae 86-028NP 3429742 YP_248022.1 CDS NTHI0421 NC_007146.2 405340 405762 D hypothetical protein 405340..405762 Haemophilus influenzae 86-028NP 3429743 YP_248023.1 CDS NTHI0422 NC_007146.2 405771 406544 D hypothetical protein 405771..406544 Haemophilus influenzae 86-028NP 3429744 YP_248024.1 CDS NTHI0423 NC_007146.2 407079 407270 D hypothetical protein 407079..407270 Haemophilus influenzae 86-028NP 3429745 YP_248025.1 CDS NTHI0424 NC_007146.2 407319 407471 D hypothetical protein 407319..407471 Haemophilus influenzae 86-028NP 3429746 YP_248026.1 CDS NTHI0425 NC_007146.2 407638 408528 R hypothetical protein complement(407638..408528) Haemophilus influenzae 86-028NP 3429747 YP_248027.1 CDS proC NC_007146.2 409189 410004 D P5CR; P5C reductase; catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 409189..410004 Haemophilus influenzae 86-028NP 3429748 YP_248028.1 CDS hcaT NC_007146.2 410004 411170 D transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 410004..411170 Haemophilus influenzae 86-028NP 3429749 YP_248029.1 CDS xerD NC_007146.2 411201 412094 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 411201..412094 Haemophilus influenzae 86-028NP 3429750 YP_248030.1 CDS NTHI0429 NC_007146.2 412267 412554 D Similar to: HI0310, Y310_HAEIN; hypothetical protein 412267..412554 Haemophilus influenzae 86-028NP 3429751 YP_248031.1 CDS ruvB NC_007146.2 412606 413613 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(412606..413613) Haemophilus influenzae 86-028NP 3429752 YP_248032.1 CDS ruvA NC_007146.2 413621 414235 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(413621..414235) Haemophilus influenzae 86-028NP 3429753 YP_248033.1 CDS ruvC NC_007146.2 414298 414870 R holliday junction nuclease RuvC; holliday juction resolvase RuvC; endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(414298..414870) Haemophilus influenzae 86-028NP 3429754 YP_248034.1 CDS NTHI0433 NC_007146.2 414917 415657 R Similar to: HI0315, Y315_HAEIN; hypothetical protein complement(414917..415657) Haemophilus influenzae 86-028NP 3429755 YP_248035.1 CDS ntpA NC_007146.2 415669 416142 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(415669..416142) Haemophilus influenzae 86-028NP 3429756 YP_248036.1 CDS aspS NC_007146.2 416164 417930 R aspartate--tRNA ligase; AspRS; catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(416164..417930) Haemophilus influenzae 86-028NP 3429757 YP_248037.1 CDS NTHI0436 NC_007146.2 418149 418667 D Similar to: HI0318, Y318_HAEIN; hypothetical protein 418149..418667 Haemophilus influenzae 86-028NP 3429758 YP_248038.1 CDS NTHI0438 NC_007146.2 418720 419445 D fold typical of S-adenosyl-L-methionine-dependent methyltransferases; Similar to: HI0319, YECO_HAEIN; hypothetical protein 418720..419445 Haemophilus influenzae 86-028NP 3429759 YP_248039.1 CDS NTHI0439 NC_007146.2 419538 419774 D Similar to: HI0321, Y321_HAEIN; hypothetical protein 419538..419774 Haemophilus influenzae 86-028NP 3429760 YP_248040.1 CDS NTHI0440 NC_007146.2 419771 420175 D Similar to: HI0322, Y322_HAEIN; nucleic acid-binding protein 419771..420175 Haemophilus influenzae 86-028NP 3429761 YP_248041.1 CDS gloA NC_007146.2 420242 420649 D methylglyoxalase; aldoketomutase; glyoxalase I; Glx I; Ketone-aldehyde mutase; S-D-lactoylglutathione methylglyoxal lyase; Similar to: HI0323, LGUL_HAEIN; lactoylglutathione lyase 420242..420649 Haemophilus influenzae 86-028NP 3429762 YP_248042.1 CDS rnt NC_007146.2 420723 421412 D exoribonuclease T; RNase T; Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 420723..421412 Haemophilus influenzae 86-028NP 3429763 YP_248043.1 CDS NTHI0443 NC_007146.2 421726 423078 D Similar to: HI0325, Y325_HAEIN; hypothetical protein 421726..423078 Haemophilus influenzae 86-028NP 3429764 YP_248044.1 CDS NTHI0444 NC_007146.2 423111 423698 D Similar to: HI0326, Y326_HAEIN; primosomal replication protein N 423111..423698 Haemophilus influenzae 86-028NP 3429765 YP_248045.1 CDS efp NC_007146.2 424049 424615 R EF-P; Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(424049..424615) Haemophilus influenzae 86-028NP 3429767 YP_248046.1 CDS NTHI0447 NC_007146.2 424653 425669 D Similar to: HI0329, YJEK_HAEIN; lysine 2,3-aminomutase 424653..425669 Haemophilus influenzae 86-028NP 3429768 YP_248047.1 CDS oapA NC_007146.2 425768 427063 D Similar to: HI0330, OAPA_HAEIN; opacity associated protein 425768..427063 Haemophilus influenzae 86-028NP 3429769 YP_248048.1 CDS oapB NC_007146.2 427122 427526 D Similar to: HI0331, OAPB_HAEIN; opacity associated protein OapB 427122..427526 Haemophilus influenzae 86-028NP 3429770 YP_248049.1 CDS recO NC_007146.2 427529 428239 D recombination protein O; involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 427529..428239 Haemophilus influenzae 86-028NP 3429771 YP_248050.1 CDS rumA NC_007146.2 428239 429555 D 23S rRNA(M-5-U1939)-methyltransferase; in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 428239..429555 Haemophilus influenzae 86-028NP 3429772 YP_248051.1 CDS relA NC_007146.2 429633 431864 D ATP:GTP 3'-pyrophosphotransferase; ppGpp synthetase I; (P)ppGpp synthetase; Similar to: HI0334, RELA_HAEIN; GTP pyrophosphokinase 429633..431864 Haemophilus influenzae 86-028NP 3429773 YP_248052.1 CDS dgkA NC_007146.2 431879 432235 D DAGK; diglyceride kinase; DGK; Similar to: HI0335, KDGL_HAEIN; diacylglycerol kinase 431879..432235 Haemophilus influenzae 86-028NP 3429774 YP_248053.1 CDS mogA NC_007146.2 432318 432911 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 432318..432911 Haemophilus influenzae 86-028NP 3429775 YP_248054.1 CDS glnB NC_007146.2 432913 433251 D Similar to: HI0337, GLNB_HAEIN; nitrogen regulatory protein P-II 432913..433251 Haemophilus influenzae 86-028NP 3429776 YP_248055.1 CDS NTHI0457 NC_007146.2 433251 434297 D Similar to: HI0338, YHHT_HAEIN; hypothetical protein 433251..434297 Haemophilus influenzae 86-028NP 3429777 YP_248056.1 CDS priA NC_007146.2 434339 436531 R replication factor Y; binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(434339..436531) Haemophilus influenzae 86-028NP 3429778 YP_248057.1 CDS trmB NC_007146.2 436616 437356 D tRNA(m7G46)-methyltransferase; tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 436616..437356 Haemophilus influenzae 86-028NP 3429779 YP_248058.1 CDS NTHI0460 NC_007146.2 437441 437785 D Similar to: HI0341, YGGL_HAEIN; hypothetical protein 437441..437785 Haemophilus influenzae 86-028NP 3429780 YP_248059.1 CDS napF NC_007146.2 437991 438521 D Similar to: HI0342, NAPF_HAEIN; ferredoxin-type protein NapF 437991..438521 Haemophilus influenzae 86-028NP 3429781 YP_248060.1 CDS napD NC_007146.2 438514 438795 D Similar to: HI0343, NAPD_HAEIN; NapD 438514..438795 Haemophilus influenzae 86-028NP 3429782 YP_248061.1 CDS napA NC_007146.2 438817 441315 D periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 438817..441315 Haemophilus influenzae 86-028NP 3429783 YP_248062.1 CDS napG NC_007146.2 441369 442208 D part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 441369..442208 Haemophilus influenzae 86-028NP 3429784 YP_248063.1 CDS napH NC_007146.2 442208 443071 D part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 442208..443071 Haemophilus influenzae 86-028NP 3429785 YP_248064.1 CDS napB NC_007146.2 443068 443520 D Similar to: HI0347, NAPB_HAEIN; diheme cytochrome C NapB 443068..443520 Haemophilus influenzae 86-028NP 3429786 YP_248065.1 CDS napC NC_007146.2 443535 444137 D Similar to: HI0348, NAPC_HAEIN; cytochrome C-type protein NapC 443535..444137 Haemophilus influenzae 86-028NP 3429787 YP_248066.1 CDS adk NC_007146.2 444297 444941 R ATP-AMP transphosphorylase; essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(444297..444941) Haemophilus influenzae 86-028NP 3429788 YP_248067.1 CDS lic3C NC_007146.2 445026 446303 R Similar to: HI0350, Y350_HAEIN; integral membrane signal transducer protein complement(445026..446303) Haemophilus influenzae 86-028NP 3429789 YP_248068.1 CDS galE NC_007146.2 446445 447461 R galactowaldenase; UDP-galactose 4-epimerase; Similar to: HI0351, GALE_HAEIN; UDP-glucose 4-epimerase complement(446445..447461) Haemophilus influenzae 86-028NP 3429790 YP_248069.1 CDS lic3A NC_007146.2 447634 448596 R Similar to: HI0352, Y352_HAEIN; CMP-Neu5Ac--lipooligosaccharide alpha 2-3 sialyltransferase complement(447634..448596) Haemophilus influenzae 86-028NP 3429791 YP_248070.1 CDS NTHI0473 NC_007146.2 448995 449717 D Similar to: HI0354, Y354_HAEIN; ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase 448995..449717 Haemophilus influenzae 86-028NP 3429792 YP_248071.1 CDS NTHI0474 NC_007146.2 449714 450451 D Similar to: HI0355, Y355_HAEIN; ABC-type nitrate/sulfonate/bicarbonate transport system, permease 449714..450451 Haemophilus influenzae 86-028NP 3429793 YP_248072.1 CDS NTHI0475 NC_007146.2 450473 451417 D Similar to: HI0357, Y357_HAEIN; ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic component 450473..451417 Haemophilus influenzae 86-028NP 3429794 YP_248073.1 CDS NTHI0476 NC_007146.2 451427 452074 D Similar to: HI0358, Y358_HAEIN; transcription activator 451427..452074 Haemophilus influenzae 86-028NP 3429795 YP_248074.1 CDS hfeD NC_007146.2 452169 452984 R Similar to: HI0359, Y359_HAEIN; ABC-type chelated iron transport system, permease complement(452169..452984) Haemophilus influenzae 86-028NP 3429796 YP_248075.1 CDS hfeC NC_007146.2 452977 453825 R Similar to: HI0360, Y360_HAEIN; ABC-type chelated iron transport system, permease complement(452977..453825) Haemophilus influenzae 86-028NP 3429797 YP_248076.1 CDS hfeB NC_007146.2 453829 454749 R Similar to: HI0361, Y361_HAEIN; ABC-type chelated iron transport system, ATPase complement(453829..454749) Haemophilus influenzae 86-028NP 3429798 YP_248077.1 CDS hfeA NC_007146.2 454749 455630 R Similar to: HI0362, Y362_HAEIN; periplasmic chelated iron binding protein complement(454749..455630) Haemophilus influenzae 86-028NP 3429799 YP_248078.1 CDS NTHI0482 NC_007146.2 455936 456400 D hypothetical protein 455936..456400 Haemophilus influenzae 86-028NP 3429800 YP_248079.1 CDS pbpG NC_007146.2 456492 457370 R PBP-7; D-alanyl-D-alanine-endopeptidase; DD-endopeptidase; Similar to: HI0364, PBP7_HAEIN; penicillin-binding protein 7-like protein complement(456492..457370) Haemophilus influenzae 86-028NP 3429801 YP_248080.1 CDS NTHI0485 NC_007146.2 457595 458767 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 457595..458767 Haemophilus influenzae 86-028NP 3429802 YP_248081.1 CDS NTHI0486 NC_007146.2 458867 459406 D Similar to: HI0366, Y366_HAEIN; hypothetical protein 458867..459406 Haemophilus influenzae 86-028NP 3429803 YP_248082.1 CDS NTHI0487 NC_007146.2 459478 460389 D Similar to: HI0367, Y367_HAEIN; hypothetical protein 459478..460389 Haemophilus influenzae 86-028NP 3429804 YP_248083.1 CDS ispG NC_007146.2 460398 461504 D 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 460398..461504 Haemophilus influenzae 86-028NP 3429805 YP_248084.1 CDS hisS NC_007146.2 461514 462785 D histidine--tRNA ligase; HisRS; catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 461514..462785 Haemophilus influenzae 86-028NP 3429806 YP_248085.1 CDS NTHI0490 NC_007146.2 462803 463417 D Similar to: HI0370, Y370_HAEIN; hypothetical protein 462803..463417 Haemophilus influenzae 86-028NP 3429807 YP_248086.1 CDS NTHI0491 NC_007146.2 463468 463662 R Similar to: HI0371, YFHJ_HAEIN; hypothetical protein complement(463468..463662) Haemophilus influenzae 86-028NP 3429808 YP_248087.1 CDS fdx NC_007146.2 463662 464003 R Similar to: HI0372, FER_HAEIN; (2Fe-2S) ferredoxin complement(463662..464003) Haemophilus influenzae 86-028NP 3429809 YP_248088.1 CDS hscA NC_007146.2 464043 465902 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(464043..465902) Haemophilus influenzae 86-028NP 3429810 YP_248089.1 CDS NTHI0494 NC_007146.2 465921 466607 R Similar to: HI0374, YBFG_HAEIN; hypothetical protein complement(465921..466607) Haemophilus influenzae 86-028NP 3429811 YP_248090.1 CDS hscB NC_007146.2 466658 467182 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(466658..467182) Haemophilus influenzae 86-028NP 3429812 YP_248091.1 CDS NTHI0496 NC_007146.2 467195 467518 R Similar to: HI0376, YFHF_HAEIN; hypothetical protein complement(467195..467518) Haemophilus influenzae 86-028NP 3429813 YP_248092.1 CDS nifU NC_007146.2 467576 467956 R Similar to: HI0377, NIFU_HAEIN; scaffold protein complement(467576..467956) Haemophilus influenzae 86-028NP 3429814 YP_248093.1 CDS nifS2 NC_007146.2 468016 469236 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(468016..469236) Haemophilus influenzae 86-028NP 3429815 YP_248094.1 CDS NTHI0499 NC_007146.2 469297 469749 R Similar to: HI0379, YFHP_HAEIN; hypothetical protein complement(469297..469749) Haemophilus influenzae 86-028NP 3429816 YP_248095.1 CDS NTHI0500 NC_007146.2 469802 470527 R Similar to: HI0380, YFHQ_HAEIN; tRNA/rRNA methyltransferase complement(469802..470527) Haemophilus influenzae 86-028NP 3429817 YP_248096.1 CDS pal NC_007146.2 470967 471428 R OMP P6; 15 kDa peptidoglycan-associated lipoprotein; PC protein; Similar to: HI0381, PAL_HAEIN; outer membrane protein P6 complement(470967..471428) Haemophilus influenzae 86-028NP 3429820 YP_248097.1 CDS tolB NC_007146.2 471452 472735 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(471452..472735) Haemophilus influenzae 86-028NP 3429821 YP_248098.1 CDS tolA NC_007146.2 472777 474003 R inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA complement(472777..474003) Haemophilus influenzae 86-028NP 3429822 YP_248099.1 CDS tolR NC_007146.2 474019 474438 R membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR complement(474019..474438) Haemophilus influenzae 86-028NP 3429823 YP_248100.1 CDS tolQ NC_007146.2 474509 475195 R Similar to: HI0385, TOLQ_HAEIN; hypothetical protein complement(474509..475195) Haemophilus influenzae 86-028NP 3429824 YP_248101.1 CDS NTHI0506 NC_007146.2 475212 475622 R Similar to: HI0386, YBGC_HAEIN; thioesterase complement(475212..475622) Haemophilus influenzae 86-028NP 3429825 YP_248102.1 CDS dinG NC_007146.2 475947 477869 D Similar to: HI0387, YOAA_HAEIN; ATP-dependent helicase 475947..477869 Haemophilus influenzae 86-028NP 3429826 YP_248103.1 CDS NTHI0508 NC_007146.2 477882 478592 D Similar to: HI0388, YEAZ_HAEIN; hypothetical protein 477882..478592 Haemophilus influenzae 86-028NP 3429827 YP_248104.1 CDS NTHI0509 NC_007146.2 478617 479168 D Similar to: HI0389, Y389_HAEIN; starvation-inducible outer membrane lipoprotein 478617..479168 Haemophilus influenzae 86-028NP 3429828 YP_248105.1 CDS lcfA NC_007146.2 479210 480898 D long-chain acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 479210..480898 Haemophilus influenzae 86-028NP 3429829 YP_248106.1 CDS rnd NC_007146.2 480954 482096 D RNase D; Similar to: HI0390, RND_HAEIN; ribonuclease D 480954..482096 Haemophilus influenzae 86-028NP 3429830 YP_248107.1 CDS NTHI0512 NC_007146.2 482139 484007 R Similar to: HI0392, Y392_HAEIN; acyltransferase complement(482139..484007) Haemophilus influenzae 86-028NP 3429831 YP_248108.1 CDS NTHI0513 NC_007146.2 484081 485172 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(484081..485172) Haemophilus influenzae 86-028NP 3429832 YP_248109.1 CDS pth NC_007146.2 485220 485804 R PTH; Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(485220..485804) Haemophilus influenzae 86-028NP 3429833 YP_248110.1 CDS NTHI0516 NC_007146.2 485987 486295 D Similar to: HI0395, YFJF_HAEIN; hypothetical protein 485987..486295 Haemophilus influenzae 86-028NP 3429834 YP_248111.1 CDS NTHI0517 NC_007146.2 486298 487512 D Similar to: HI0396, YCFD_HAEIN; hypothetical protein 486298..487512 Haemophilus influenzae 86-028NP 3429835 YP_248112.1 CDS xseA NC_007146.2 487514 488833 D exonuclease VII large subunit; bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 487514..488833 Haemophilus influenzae 86-028NP 3429836 YP_248113.1 CDS adpP NC_007146.2 489010 489663 D ADP-ribose diphosphatase; adenosine diphosphoribose pyrophosphatase; ADPR-PPase; ADP-ribose phosphohydrolase; Similar to: HI0398, ADPP_HAEIN; ADP-ribose pyrophosphatase 489010..489663 Haemophilus influenzae 86-028NP 3429837 YP_248114.1 CDS icc NC_007146.2 489673 490497 D Similar to: HI0399, ICC_HAEIN; cyclic 3',5'-adenosine monophosphate phosphodiesterase 489673..490497 Haemophilus influenzae 86-028NP 3429838 YP_248115.1 CDS NTHI0521 NC_007146.2 490595 490882 R Similar to: HI0400, Y400_HAEIN; hypothetical protein complement(490595..490882) Haemophilus influenzae 86-028NP 3429839 YP_248116.1 CDS ompP1 NC_007146.2 491079 492455 D OMP P1; Similar to: HI0401, OM12_HAEIN; long-chain fatty acid ABC transporter 491079..492455 Haemophilus influenzae 86-028NP 3429840 YP_248117.1 CDS ogt NC_007146.2 492501 493070 D 6-O-methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase; Similar to: HI0402, OGT_HAEIN; methylated-DNA--protein-cysteine methyltransferase 492501..493070 Haemophilus influenzae 86-028NP 3429841 YP_248118.1 CDS mutH NC_007146.2 493067 493738 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 493067..493738 Haemophilus influenzae 86-028NP 3429842 YP_248119.1 CDS mesJ NC_007146.2 493746 495038 R Similar to: HI0404, MESJ_HAEIN; cell cycle protein MesJ complement(493746..495038) Haemophilus influenzae 86-028NP 3429843 YP_248120.1 CDS accA NC_007146.2 495215 496162 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha complement(495215..496162) Haemophilus influenzae 86-028NP 3429845 YP_248121.1 CDS znuB NC_007146.2 496251 497036 R Similar to: HI0407, ZNUB_HAEIN; high-affinity zinc uptake system membrane protein ZnuB complement(496251..497036) Haemophilus influenzae 86-028NP 3429846 YP_248122.1 CDS znuC NC_007146.2 497036 497842 R Similar to: HI0408, ZNUC_HAEIN; ABC transporter ATP-binding protein complement(497036..497842) Haemophilus influenzae 86-028NP 3429847 YP_248123.1 CDS NTHI0532 NC_007146.2 498014 499441 D Similar to: HI0409, Y409_HAEIN; metalloprotease 498014..499441 Haemophilus influenzae 86-028NP 3429848 YP_248124.1 CDS tyrR NC_007146.2 499556 500512 D Similar to: HI0410, TYRR_HAEIN; transcriptional regulatory protein TyrR 499556..500512 Haemophilus influenzae 86-028NP 3429849 YP_248125.1 CDS hfq NC_007146.2 500608 500883 R Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq complement(500608..500883) Haemophilus influenzae 86-028NP 3429850 YP_248126.1 CDS rluC NC_007146.2 500974 501969 R pseudouridylate synthase; Uracil hydrolyase; catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C complement(500974..501969) Haemophilus influenzae 86-028NP 3429851 YP_248127.1 CDS rne NC_007146.2 502315 505170 D RNase E; Similar to: HI0413, RNE_HAEIN; ribonuclease E 502315..505170 Haemophilus influenzae 86-028NP 3429852 YP_248128.1 CDS NTHI0539 NC_007146.2 505402 505614 D Similar to: HI0414, Y414_HAEIN; hypothetical protein 505402..505614 Haemophilus influenzae 86-028NP 3429853 YP_248129.1 CDS thiM NC_007146.2 505938 506735 D 4-methyl-5-beta-hydroxyethylthiazole kinase; Thz kinase; TH kinase; catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 505938..506735 Haemophilus influenzae 86-028NP 3429854 YP_248130.1 CDS thiD NC_007146.2 506728 507537 D HMP-phosphate kinase; HMP-P kinase; catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 506728..507537 Haemophilus influenzae 86-028NP 3429855 YP_248131.1 CDS thiE NC_007146.2 507548 508228 D TMP pyrophosphorylase; TMP-PPase; thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 507548..508228 Haemophilus influenzae 86-028NP 3429856 YP_248132.1 CDS NTHI0543 NC_007146.2 508212 509516 D Similar to: HI0418, Y418_HAEIN; metabolite transporter 508212..509516 Haemophilus influenzae 86-028NP 3429857 YP_248133.1 CDS NTHI0544 NC_007146.2 509528 509629 R hypothetical protein complement(509528..509629) Haemophilus influenzae 86-028NP 3429858 YP_248134.1 CDS NTHI0545 NC_007146.2 509685 511064 D Similar to: HI0419, YEGQ_HAEIN; protease 509685..511064 Haemophilus influenzae 86-028NP 3429859 YP_248135.1 CDS srmB NC_007146.2 511098 512417 R facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB complement(511098..512417) Haemophilus influenzae 86-028NP 3429860 YP_248136.1 CDS NTHI0547 NC_007146.2 512463 513185 D Similar to: HI0423, YFIC_HAEIN; O-methyltransferase 512463..513185 Haemophilus influenzae 86-028NP 3429861 YP_248137.1 CDS pssA NC_007146.2 513968 515335 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 513968..515335 Haemophilus influenzae 86-028NP 3429863 YP_248138.1 CDS fadR NC_007146.2 515381 516106 R Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator complement(515381..516106) Haemophilus influenzae 86-028NP 3429864 YP_248139.1 CDS nhaB NC_007146.2 516207 517775 D Sodium/proton antiporter 2; involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 516207..517775 Haemophilus influenzae 86-028NP 3429865 YP_248140.1 CDS dsbB NC_007146.2 517785 518318 D disulfide oxidoreductase; disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 517785..518318 Haemophilus influenzae 86-028NP 3429866 YP_248141.1 CDS glmS NC_007146.2 518373 520205 R hexosephosphate aminotransferase; D-fructose-6-phosphate amidotransferase; GFAT; L-glutamine-D-fructose-6-phosphate amidotransferase; glucosamine-6-phosphate synthase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(518373..520205) Haemophilus influenzae 86-028NP 3429867 YP_248142.1 CDS hupA NC_007146.2 520318 520728 R Similar to: HI0430, DBH_HAEIN; DNA-binding protein HU complement(520318..520728) Haemophilus influenzae 86-028NP 3429868 YP_248143.1 CDS NTHI0555 NC_007146.2 520730 521320 R Similar to: HI0431, YJAG_HAEIN; hypothetical protein complement(520730..521320) Haemophilus influenzae 86-028NP 3429869 YP_248144.1 CDS nudC NC_007146.2 521356 522150 R can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase complement(521356..522150) Haemophilus influenzae 86-028NP 3429870 YP_248145.1 CDS orfG NC_007146.2 522217 522813 R cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein complement(522217..522813) Haemophilus influenzae 86-028NP 3429871 YP_248146.1 CDS comF NC_007146.2 522889 523575 R DNA transformation protein comF; protein COM101A; Similar to: HI0434, COMF_HAEIN; competence protein F complement(522889..523575) Haemophilus influenzae 86-028NP 3429872 YP_248147.1 CDS comE NC_007146.2 523588 524925 R DNA transformation protein comE; Similar to: HI0435, COME_HAEIN; competence protein E complement(523588..524925) Haemophilus influenzae 86-028NP 3429873 YP_248148.1 CDS comD NC_007146.2 524935 525348 R DNA transformation protein comD; Similar to: HI0436, COMD_HAEIN; competence protein D complement(524935..525348) Haemophilus influenzae 86-028NP 3429874 YP_248149.1 CDS comC NC_007146.2 525345 525866 R DNA transformation protein comC; Similar to: HI0437, COMC_HAEIN; competence protein C complement(525345..525866) Haemophilus influenzae 86-028NP 3429875 YP_248150.1 CDS comB NC_007146.2 525863 526369 R DNA transformation protein comB; Similar to: HI0438, COMB_HAEIN; competence protein B complement(525863..526369) Haemophilus influenzae 86-028NP 3429876 YP_248151.1 CDS comA NC_007146.2 526370 527167 R DNA transformation protein comA; Similar to: HI0439, COMA_HAEIN; competence protein A complement(526370..527167) Haemophilus influenzae 86-028NP 3429877 YP_248152.1 CDS mrcA NC_007146.2 527266 529860 D PBP-1a; PBP1a; penicillin-binding protein A; peptidoglycan TGase; DD-transpeptidase; Similar to: HI0440, PBPA_HAEIN; penicillin-binding protein 1A 527266..529860 Haemophilus influenzae 86-028NP 3429878 YP_248153.1 CDS NTHI0568 NC_007146.2 529933 530778 D Similar to: HI0441, YHIR_HAEIN; hypothetical protein 529933..530778 Haemophilus influenzae 86-028NP 3429879 YP_248154.1 CDS NTHI0569 NC_007146.2 530911 531276 D Similar to: HI0442, Y442_HAEIN; hypothetical protein 530911..531276 Haemophilus influenzae 86-028NP 3429880 YP_248155.1 CDS recR NC_007146.2 531407 532009 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 531407..532009 Haemophilus influenzae 86-028NP 3429881 YP_248156.1 CDS topB NC_007146.2 532025 533980 D decatenates replicating daughter chromosomes; DNA topoisomerase III 532025..533980 Haemophilus influenzae 86-028NP 3429882 YP_248157.1 CDS secG NC_007146.2 534089 534430 D Similar to: HI0445, SECG_HAEIN; preprotein translocase subunit SecG 534089..534430 Haemophilus influenzae 86-028NP 3429883 YP_248158.1 CDS fruA NC_007146.2 534975 536645 R EIIBC-Fru; fructose-permease IIBC component; phosphotransferase enzyme II, BC component; EII-Fru; Similar to: HI0446, PTFB_HAEIN; PTS system, fructose-specific IIBC component complement(534975..536645) Haemophilus influenzae 86-028NP 3429885 YP_248159.1 CDS fruK NC_007146.2 536647 537588 R fructose 1-phosphate kinase; converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(536647..537588) Haemophilus influenzae 86-028NP 3429886 YP_248160.1 CDS fruB NC_007146.2 537590 539089 R EIIA-Fru; fructose-permease IIA/FPr component; phosphotransferase enzyme II, A/FPr component; phosphotransferase FPr protein; Pseudo-HPr; EIII-Fru; fructose PTS diphosphoryl transfer protein; phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein complement(537590..539089) Haemophilus influenzae 86-028NP 3429887 YP_248161.1 CDS NTHI0576 NC_007146.2 539161 539697 R Similar to: HI0449, Y449_HAEIN; hypothetical protein complement(539161..539697) Haemophilus influenzae 86-028NP 3429888 YP_248162.1 CDS vapD NC_007146.2 539784 540062 R Similar to: HI0450, VAPD_HAEIN; virulence-associated protein D complement(539784..540062) Haemophilus influenzae 86-028NP 3429889 YP_248163.1 CDS vapX NC_007146.2 540071 540262 R Similar to: HI0451, Y451_HAEIN; hypothetical protein complement(540071..540262) Haemophilus influenzae 86-028NP 3429890 YP_248164.1 CDS NTHI0579 NC_007146.2 540334 541632 R Similar to: HI0452, YTFL_HAEIN; hypothetical protein complement(540334..541632) Haemophilus influenzae 86-028NP 3429891 YP_248165.1 CDS NTHI0580 NC_007146.2 541683 542207 R Similar to: HI0453, Y453_HAEIN; hypothetical protein complement(541683..542207) Haemophilus influenzae 86-028NP 3429892 YP_248166.1 CDS NTHI0581 NC_007146.2 542234 543016 R Similar to: HI0454, YCFH_HAEIN; deoxyribonuclease complement(542234..543016) Haemophilus influenzae 86-028NP 3429893 YP_248167.1 CDS holB NC_007146.2 543071 544054 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' complement(543071..544054) Haemophilus influenzae 86-028NP 3429894 YP_248168.1 CDS NTHI0584 NC_007146.2 544051 544179 R hypothetical protein complement(544051..544179) Haemophilus influenzae 86-028NP 3429895 YP_248169.1 CDS lav NC_007146.2 544254 546377 D Similar to: YDEU_ECOLI; autotransported protein Lav 544254..546377 Haemophilus influenzae 86-028NP 3429896 YP_248170.1 CDS tmk NC_007146.2 547283 547942 R dTMP kinase; catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(547283..547942) Haemophilus influenzae 86-028NP 3429897 YP_248171.1 CDS NTHI0587 NC_007146.2 547932 548975 R Similar to: HI0457, YCEG_HAEIN; periplasmic solute-binding protein complement(547932..548975) Haemophilus influenzae 86-028NP 3429898 YP_248172.1 CDS surA NC_007146.2 549045 549986 R Similar to: HI0458, SURA_HAEIN; survival protein SurA-like protein complement(549045..549986) Haemophilus influenzae 86-028NP 3429899 YP_248173.1 CDS pyrR NC_007146.2 550056 550595 R UPRTase; regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase complement(550056..550595) Haemophilus influenzae 86-028NP 3429900 YP_248174.1 CDS mazG NC_007146.2 550727 551518 D functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 550727..551518 Haemophilus influenzae 86-028NP 3429901 YP_248175.1 CDS NTHI0592 NC_007146.2 551568 552443 R Similar to: HI0461, Y461_HAEIN; hypothetical protein complement(551568..552443) Haemophilus influenzae 86-028NP 3429902 YP_248176.1 CDS lon NC_007146.2 552636 555047 D Lon protease; Similar to: HI0462, LON_HAEIN; ATP-dependent protease La 552636..555047 Haemophilus influenzae 86-028NP 3429903 YP_248177.1 CDS NTHI0594 NC_007146.2 555164 556315 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 555164..556315 Haemophilus influenzae 86-028NP 3429904 YP_248178.1 CDS rpiA NC_007146.2 556449 557108 D phosphoriboisomerase A; PRI; Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 556449..557108 Haemophilus influenzae 86-028NP 3429905 YP_248179.1 CDS serA NC_007146.2 557138 558370 D PGDH; catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 557138..558370 Haemophilus influenzae 86-028NP 3429906 YP_248180.1 CDS NTHI0597 NC_007146.2 558413 559255 R Similar to: HI0466, Y466_HAEIN; glycine cleavage system protein T complement(558413..559255) Haemophilus influenzae 86-028NP 3429907 YP_248181.1 CDS NTHI0598 NC_007146.2 559265 560128 R Similar to: HI0467, YICC_HAEIN; hypothetical protein complement(559265..560128) Haemophilus influenzae 86-028NP 3429908 YP_248182.1 CDS hisG NC_007146.2 560577 561488 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 560577..561488 Haemophilus influenzae 86-028NP 3429909 YP_248183.1 CDS hisD NC_007146.2 561581 562864 D HDH; catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 561581..562864 Haemophilus influenzae 86-028NP 3429910 YP_248184.1 CDS hisC NC_007146.2 562933 564036 D imidazole acetol-phosphate transaminase 1; catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 562933..564036 Haemophilus influenzae 86-028NP 3429911 YP_248185.1 CDS hisB NC_007146.2 564148 565236 D IGPD; catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 564148..565236 Haemophilus influenzae 86-028NP 3429912 YP_248186.1 CDS hisH NC_007146.2 565302 565901 D IGP synthase glutamine amidotransferase subunit; IGP synthase subunit HisH; ImGP synthase subunit HisH; IGPS subunit HisH; with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 565302..565901 Haemophilus influenzae 86-028NP 3429913 YP_248187.1 CDS hisA NC_007146.2 565937 566686 D 5-phosphoribosyl; 5-phosphoribosylamino; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 565937..566686 Haemophilus influenzae 86-028NP 3429914 YP_248188.1 CDS hisF NC_007146.2 566668 567444 D IGP synthase cyclase subunit; IGP synthase subunit HisF; ImGP synthase subunit HisF; IGPS subunit HisF; catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 566668..567444 Haemophilus influenzae 86-028NP 3429915 YP_248189.1 CDS hisI NC_007146.2 567444 568109 D PRA-CH; PRA-PH; catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 567444..568109 Haemophilus influenzae 86-028NP 3429916 YP_248190.1 CDS NTHI0606_1 NC_007146.2 568191 568343 D hypothetical protein 568191..568343 Haemophilus influenzae 86-028NP 3429917 YP_248191.1 CDS tyrP NC_007146.2 568373 569575 D TyrP-A; tyrosine permease 1; Similar to: HI0477, TYRP_HAEIN; tyrosine-specific transport protein 1 568373..569575 Haemophilus influenzae 86-028NP 3429918 YP_248192.1 CDS atpC NC_007146.2 569761 570189 R ATP synthase F1 sector epsilon subunit; part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon complement(569761..570189) Haemophilus influenzae 86-028NP 3429919 YP_248193.1 CDS atpD NC_007146.2 570219 571592 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta complement(570219..571592) Haemophilus influenzae 86-028NP 3429920 YP_248194.1 CDS atpG NC_007146.2 571609 572478 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma complement(571609..572478) Haemophilus influenzae 86-028NP 3429921 YP_248195.1 CDS atpA NC_007146.2 572494 574035 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha complement(572494..574035) Haemophilus influenzae 86-028NP 3429922 YP_248196.1 CDS atpH NC_007146.2 574048 574581 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta complement(574048..574581) Haemophilus influenzae 86-028NP 3429923 YP_248197.1 CDS atpF NC_007146.2 574594 575064 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B complement(574594..575064) Haemophilus influenzae 86-028NP 3429924 YP_248198.1 CDS atpE NC_007146.2 575114 575368 R Lipid-binding protein; dicyclohexylcarbodiimide-binding protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C complement(575114..575368) Haemophilus influenzae 86-028NP 3429925 YP_248199.1 CDS atpB NC_007146.2 575424 576212 R protein 6; Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A complement(575424..576212) Haemophilus influenzae 86-028NP 3429926 YP_248200.1 CDS NTHI0616 NC_007146.2 576249 576623 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(576249..576623) Haemophilus influenzae 86-028NP 3429927 YP_248201.1 CDS gidB NC_007146.2 576749 577360 R glucose inhibited division protein B; glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(576749..577360) Haemophilus influenzae 86-028NP 3429928 YP_248202.1 CDS NTHI0618 NC_007146.2 577500 577877 R Similar to: HI0487, YHFY_HAEIN; hypothetical protein complement(577500..577877) Haemophilus influenzae 86-028NP 3429929 YP_248203.1 CDS NTHI0619 NC_007146.2 577993 578595 D Similar to: HI0488, YQAB_HAEIN; phosphatase/phosphohexomutase 577993..578595 Haemophilus influenzae 86-028NP 3429930 YP_248204.1 CDS NTHI0620 NC_007146.2 578595 579068 D Similar to: HI0489, YQAA_HAEIN; hypothetical protein 578595..579068 Haemophilus influenzae 86-028NP 3429931 YP_248205.1 CDS luxS NC_007146.2 579253 579756 D autoinducer-2 production protein LuxS; AI-2 synthesis protein; catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 579253..579756 Haemophilus influenzae 86-028NP 3429932 YP_248206.1 CDS aphA NC_007146.2 580700 581407 R Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase complement(580700..581407) Haemophilus influenzae 86-028NP 3429933 YP_248207.1 CDS hslV NC_007146.2 581627 582154 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 581627..582154 Haemophilus influenzae 86-028NP 3429934 YP_248208.1 CDS hslU NC_007146.2 582165 583499 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 582165..583499 Haemophilus influenzae 86-028NP 3429935 YP_248209.1 CDS potD2 NC_007146.2 583569 584621 R SPBP; Similar to: HI0498, POT2_HAEIN; spermidine/putrescine-binding periplasmic protein 2 complement(583569..584621) Haemophilus influenzae 86-028NP 3429936 YP_248210.1 CDS ordL NC_007146.2 584761 586056 D Similar to: HI0499, ORDL_HAEIN; oxidoreductase OrdL 584761..586056 Haemophilus influenzae 86-028NP 3429937 YP_248211.1 CDS rmuC NC_007146.2 586220 587662 D Similar to: HI0500, RMUC_HAEIN; DNA recombination protein RmuC 586220..587662 Haemophilus influenzae 86-028NP 3429938 YP_248212.1 CDS rbsD NC_007146.2 587826 588245 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 587826..588245 Haemophilus influenzae 86-028NP 3429939 YP_248213.1 CDS rbsA NC_007146.2 588259 589740 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 588259..589740 Haemophilus influenzae 86-028NP 3429940 YP_248214.1 CDS rbsC NC_007146.2 589753 590724 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease protein 589753..590724 Haemophilus influenzae 86-028NP 3429941 YP_248215.1 CDS rbsB NC_007146.2 590744 591622 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 590744..591622 Haemophilus influenzae 86-028NP 3429942 YP_248216.1 CDS rbsK NC_007146.2 591720 592640 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 591720..592640 Haemophilus influenzae 86-028NP 3429943 YP_248217.1 CDS rbsR NC_007146.2 592668 593666 D Similar to: HI0506, RBSR_HAEIN; ribose operon repressor 592668..593666 Haemophilus influenzae 86-028NP 3429944 YP_248218.1 CDS NTHI0635 NC_007146.2 593772 594323 D Similar to: HI0507, YQHA_HAEIN; hypothetical protein 593772..594323 Haemophilus influenzae 86-028NP 3429945 YP_248219.1 CDS menG NC_007146.2 594463 594951 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(594463..594951) Haemophilus influenzae 86-028NP 3429946 YP_248220.1 CDS menA NC_007146.2 595003 595935 R DHNA-octaprenyltransferase; catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(595003..595935) Haemophilus influenzae 86-028NP 3429947 YP_248221.1 CDS NTHI0638 NC_007146.2 595982 596701 D Similar to: HI0510, YAEB_HAEIN; hypothetical protein 595982..596701 Haemophilus influenzae 86-028NP 3429948 YP_248222.1 CDS tehA NC_007146.2 596754 597740 R Similar to: HI0511, TEHA_HAEIN; potassium-tellurite ethidium and proflavin transporter complement(596754..597740) Haemophilus influenzae 86-028NP 3429949 YP_248223.1 CDS rpoC NC_007146.2 597892 602142 R transcriptase beta' chain; RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(597892..602142) Haemophilus influenzae 86-028NP 3429950 YP_248224.1 CDS rpoB NC_007146.2 602349 606380 R transcriptase beta chain; RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(602349..606380) Haemophilus influenzae 86-028NP 3429951 YP_248225.1 CDS rplA NC_007146.2 606764 607453 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(606764..607453) Haemophilus influenzae 86-028NP 3429952 YP_248226.1 CDS rplK NC_007146.2 607458 607886 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(607458..607886) Haemophilus influenzae 86-028NP 3429953 YP_248227.1 CDS deoD NC_007146.2 608059 608775 R inosine phosphorylase; PNP; catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase complement(608059..608775) Haemophilus influenzae 86-028NP 3429954 YP_248228.1 CDS NTHI0645 NC_007146.2 608859 610112 R Similar to: HI0519, YEIM_HAEIN; nucleoside permease complement(608859..610112) Haemophilus influenzae 86-028NP 3429955 YP_248229.1 CDS NTHI0646 NC_007146.2 610211 610999 R Similar to: HI0520, Y520_HAEIN; pyruvate-formate lyase-activating enzyme complement(610211..610999) Haemophilus influenzae 86-028NP 3429956 YP_248230.1 CDS NTHI0647 NC_007146.2 611008 612552 R Similar to: HI0521, YJJI_HAEIN; hypothetical protein complement(611008..612552) Haemophilus influenzae 86-028NP 3429957 YP_248231.1 CDS NTHI0648 NC_007146.2 612765 613421 D Similar to: HI0522, Y522_HAEIN; hypothetical protein 612765..613421 Haemophilus influenzae 86-028NP 3429958 YP_248232.1 CDS waaQ NC_007146.2 613377 614447 R Similar to: HI0523, Y523_HAEIN; ADP-heptose--lipooligosaccharide heptosyltransferase III complement(613377..614447) Haemophilus influenzae 86-028NP 3429959 YP_248233.1 CDS fba NC_007146.2 614485 615564 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(614485..615564) Haemophilus influenzae 86-028NP 3429960 YP_248234.1 CDS pgk NC_007146.2 615675 616835 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(615675..616835) Haemophilus influenzae 86-028NP 3429961 YP_248235.1 CDS NTHI0652 NC_007146.2 616931 617725 R Similar to: HI0526, RN26_HAEIN; ribonuclease I complement(616931..617725) Haemophilus influenzae 86-028NP 3429962 YP_248236.1 CDS NTHI0653 NC_007146.2 617803 618063 D Similar to: HI0527, YFHL_HAEIN; ferredoxin-like protein 617803..618063 Haemophilus influenzae 86-028NP 3429963 YP_248237.1 CDS tyrQ NC_007146.2 618197 619417 R TyrP-B; tyrosine permease 2; Similar to: HI0528, TYRQ_HAEIN; tyrosine-specific transport protein 2 complement(618197..619417) Haemophilus influenzae 86-028NP 3429964 YP_248238.1 CDS tdk NC_007146.2 619454 620035 R catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase complement(619454..620035) Haemophilus influenzae 86-028NP 3429965 YP_248239.1 CDS gcp NC_007146.2 620044 621072 R glycoprotease; in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(620044..621072) Haemophilus influenzae 86-028NP 3429966 YP_248240.1 CDS rpsU NC_007146.2 621304 621519 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 621304..621519 Haemophilus influenzae 86-028NP 3429967 YP_248241.1 CDS dnaG NC_007146.2 621653 623434 D synthesizes RNA primers at the replication forks; DNA primase 621653..623434 Haemophilus influenzae 86-028NP 3429968 YP_248242.1 CDS rpoD NC_007146.2 623505 625376 D Sigma-70; Similar to: HI0533, RPSD_HAEIN; RNA polymerase sigma factor RpoD 623505..625376 Haemophilus influenzae 86-028NP 3429969 YP_248243.1 CDS aspA NC_007146.2 625686 627113 R aspartase; catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(625686..627113) Haemophilus influenzae 86-028NP 3429970 YP_248244.1 CDS ureH NC_007146.2 627260 628075 R Similar to: HI0535, UREH_HAEIN; urease accessory protein UreH complement(627260..628075) Haemophilus influenzae 86-028NP 3429971 YP_248245.1 CDS ureG NC_007146.2 628150 628827 R Similar to: HI0536, UREG_HAEIN; urease accessory protein complement(628150..628827) Haemophilus influenzae 86-028NP 3429972 YP_248246.1 CDS ureF NC_007146.2 628930 629637 R Similar to: HI0537, UREF_HAEIN; urease accessory protein UreF complement(628930..629637) Haemophilus influenzae 86-028NP 3429973 YP_248247.1 CDS ureE NC_007146.2 629622 630179 R involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE complement(629622..630179) Haemophilus influenzae 86-028NP 3429974 YP_248248.1 CDS ureC NC_007146.2 630307 632025 R Urea amidohydrolase; ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha complement(630307..632025) Haemophilus influenzae 86-028NP 3429975 YP_248249.1 CDS ureB NC_007146.2 632037 632342 R Urea amidohydrolase; ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta complement(632037..632342) Haemophilus influenzae 86-028NP 3429976 YP_248250.1 CDS ureA NC_007146.2 632419 632721 R Urea amidohydrolase gamma subunit; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma complement(632419..632721) Haemophilus influenzae 86-028NP 3429977 YP_248251.1 CDS groES NC_007146.2 632884 633174 D Cpn10; groES; 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 632884..633174 Haemophilus influenzae 86-028NP 3429978 YP_248252.1 CDS groEL NC_007146.2 633197 634834 D Cpn60; groEL; 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 633197..634834 Haemophilus influenzae 86-028NP 3429979 YP_248253.1 CDS rplI NC_007146.2 635008 635457 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(635008..635457) Haemophilus influenzae 86-028NP 3429980 YP_248254.1 CDS rpsR NC_007146.2 635474 635701 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(635474..635701) Haemophilus influenzae 86-028NP 3429981 YP_248255.1 CDS priB NC_007146.2 635714 636040 R binds single-stranded DNA at the primosome assembly site; primosomal replication protein N complement(635714..636040) Haemophilus influenzae 86-028NP 3429982 YP_248256.1 CDS rpsF NC_007146.2 636027 636404 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(636027..636404) Haemophilus influenzae 86-028NP 3429983 YP_248257.1 CDS infA NC_007146.2 636596 636850 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(636596..636850) Haemophilus influenzae 86-028NP 3429984 YP_248258.1 CDS ksgA NC_007146.2 638183 639046 D S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase; 16S rRNA dimethylase; High level kasugamycin resistance protein ksgA; kasugamycin dimethyltransferase; catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 638183..639046 Haemophilus influenzae 86-028NP 3429986 YP_248259.1 CDS lic2A NC_007146.2 639086 640024 R Similar to: HI0550, LEX1_HAEIN; UDP-Gal--lipooligosaccharide galactosyltransferase complement(639086..640024) Haemophilus influenzae 86-028NP 3429987 YP_248260.1 CDS apaH NC_007146.2 640077 640904 D 5'-nucleosyl; diadenosine tetraphosphatase; Ap4A hydrolase; diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 640077..640904 Haemophilus influenzae 86-028NP 3429988 YP_248261.1 CDS NTHI0680 NC_007146.2 640914 641537 D Similar to: HI0552, Y552_HAEIN; hypothetical protein 640914..641537 Haemophilus influenzae 86-028NP 3429989 YP_248262.1 CDS gnd NC_007146.2 641663 643117 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(641663..643117) Haemophilus influenzae 86-028NP 3429990 YP_248263.1 CDS NTHI0683 NC_007146.2 643233 643775 R Similar to: HI0554, Y554_HAEIN; hypothetical protein complement(643233..643775) Haemophilus influenzae 86-028NP 3429991 YP_248264.1 CDS NTHI0684 NC_007146.2 643858 644046 R hypothetical protein complement(643858..644046) Haemophilus influenzae 86-028NP 3429992 YP_248265.2 CDS devB NC_007146.2 644116 644814 R 6PGL; catalyzes the formation of 6-phospho-D-gluconate from 6-phospho-D-glucono-1,5-lactone; 6-phosphogluconolactonase complement(644116..644814) Haemophilus influenzae 86-028NP 3429993 YP_248266.1 CDS zwf NC_007146.2 644957 646441 R G6PD; catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(644957..646441) Haemophilus influenzae 86-028NP 3429994 YP_248267.1 CDS cysQ NC_007146.2 646517 647326 R Similar to: HI0559, CYSQ_HAEIN; CysQ complement(646517..647326) Haemophilus influenzae 86-028NP 3429995 YP_248268.1 CDS NTHI0688 NC_007146.2 647331 647747 R Similar to: HI0559.1, Y55A_HAEIN; hypothetical protein complement(647331..647747) Haemophilus influenzae 86-028NP 3429996 YP_248269.1 CDS NTHI0689 NC_007146.2 647804 649786 R Similar to: HI0561, Y561_HAEIN; hypothetical protein complement(647804..649786) Haemophilus influenzae 86-028NP 3429997 YP_248270.1 CDS hslR NC_007146.2 650015 650410 D HSP15; Similar to: HI0562, HSLR_HAEIN; heat shock protein 15-like protein 650015..650410 Haemophilus influenzae 86-028NP 3429998 YP_248271.1 CDS asnC NC_007146.2 650436 650888 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(650436..650888) Haemophilus influenzae 86-028NP 3429999 YP_248272.1 CDS asnA NC_007146.2 651042 652034 D asparagine synthetase A; catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 651042..652034 Haemophilus influenzae 86-028NP 3430000 YP_248273.1 CDS NTHI0693 NC_007146.2 652097 652450 R Similar to: HI1721, YH21_HAEIN; transposase-like protein complement(652097..652450) Haemophilus influenzae 86-028NP 3430001 YP_248274.1 CDS NTHI0694 NC_007146.2 653063 653920 D hypothetical protein 653063..653920 Haemophilus influenzae 86-028NP 3430002 YP_248275.1 CDS NTHI0695 NC_007146.2 654077 654193 R hypothetical protein complement(654077..654193) Haemophilus influenzae 86-028NP 3430003 YP_248276.1 CDS NTHI0696 NC_007146.2 654485 654625 D hypothetical protein 654485..654625 Haemophilus influenzae 86-028NP 3430004 YP_248277.1 CDS gph NC_007146.2 654805 655479 R PGP; catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(654805..655479) Haemophilus influenzae 86-028NP 3430005 YP_248278.1 CDS rpe NC_007146.2 655525 656229 R pentose-5-phosphate 3-epimerase; PPE; R5P3E; catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(655525..656229) Haemophilus influenzae 86-028NP 3430006 YP_248279.1 CDS gyrB NC_007146.2 656351 658771 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(656351..658771) Haemophilus influenzae 86-028NP 3430007 YP_248280.1 CDS NTHI0701 NC_007146.2 658897 661209 R Similar to: HI0568, YHGF_HAEIN; transcriptional accessory protein complement(658897..661209) Haemophilus influenzae 86-028NP 3430008 YP_248281.1 CDS greB NC_007146.2 661305 661781 D transcript cleavage factor greB; necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 661305..661781 Haemophilus influenzae 86-028NP 3430009 YP_248282.1 CDS NTHI0703 NC_007146.2 661851 662468 R negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR complement(661851..662468) Haemophilus influenzae 86-028NP 3430010 YP_248283.1 CDS oxyR NC_007146.2 662468 663373 R Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR complement(662468..663373) Haemophilus influenzae 86-028NP 3430011 YP_248284.1 CDS pdgX NC_007146.2 663496 664221 D Similar to: HI0572, Y572_HAEIN; peroxiredoxin/glutaredoxin 663496..664221 Haemophilus influenzae 86-028NP 3430012 YP_248285.1 CDS slyX NC_007146.2 664313 664534 R Similar to: HI0573, SLYX_HAEIN; hypothetical protein complement(664313..664534) Haemophilus influenzae 86-028NP 3430013 YP_248286.1 CDS fkbY NC_007146.2 664632 665357 D PPIase; rotamase; Similar to: HI0574, FKBY_HAEIN; FKBP-type peptidylprolyl isomerase 664632..665357 Haemophilus influenzae 86-028NP 3430014 YP_248287.1 CDS NTHI0708 NC_007146.2 665447 666112 D Similar to: HI0575, YHEO_HAEIN; hypothetical protein 665447..666112 Haemophilus influenzae 86-028NP 3430015 YP_248288.1 CDS NTHI0709 NC_007146.2 666112 666492 D in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 666112..666492 Haemophilus influenzae 86-028NP 3430016 YP_248289.1 CDS NTHI0710 NC_007146.2 666489 666848 D in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 666489..666848 Haemophilus influenzae 86-028NP 3430017 YP_248290.1 CDS NTHI0711 NC_007146.2 666857 667144 D Similar to: HI0577, Y577_HAEIN; hypothetical protein 666857..667144 Haemophilus influenzae 86-028NP 3430018 YP_248291.1 CDS tuf NC_007146.2 667275 668459 R EF-Tu; EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(667275..668459) Haemophilus influenzae 86-028NP 3430019 YP_248292.1 CDS coaA NC_007146.2 669165 670088 D pantothenic acid kinase; catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 669165..670088 Haemophilus influenzae 86-028NP 3430024 YP_248293.1 CDS rseB NC_007146.2 670179 671126 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(670179..671126) Haemophilus influenzae 86-028NP 3430025 YP_248294.1 CDS rseA NC_007146.2 671206 671781 R Similar to: HI0629, RSEA_HAEIN; sigma-E factor negative regulatory protein complement(671206..671781) Haemophilus influenzae 86-028NP 3430026 YP_248295.1 CDS rpoE NC_007146.2 671806 672375 R Sigma-24; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(671806..672375) Haemophilus influenzae 86-028NP 3430027 YP_248296.1 CDS NTHI0720 NC_007146.2 672484 672741 R Similar to: HI0627, YGFY_HAEIN; hypothetical protein complement(672484..672741) Haemophilus influenzae 86-028NP 3430028 YP_248297.1 CDS mscL NC_007146.2 672831 673217 R forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel complement(672831..673217) Haemophilus influenzae 86-028NP 3430029 YP_248298.1 CDS trkA NC_007146.2 673290 674666 R K(+)-uptake protein trkA; involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component complement(673290..674666) Haemophilus influenzae 86-028NP 3430030 YP_248299.1 CDS sun NC_007146.2 674679 676031 R FMU protein; predicted tRNA or rRNA cytosine-C5-methylase; Similar to: HI0624, SUN_HAEIN; SUN protein complement(674679..676031) Haemophilus influenzae 86-028NP 3430031 YP_248300.1 CDS fmt NC_007146.2 676031 676987 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(676031..676987) Haemophilus influenzae 86-028NP 3430032 YP_248301.1 CDS def NC_007146.2 677088 677597 R PDF; polypeptide deformylase; cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(677088..677597) Haemophilus influenzae 86-028NP 3430033 YP_248302.1 CDS NTHI0726 NC_007146.2 677787 678224 R hypothetical protein complement(677787..678224) Haemophilus influenzae 86-028NP 3430034 YP_248303.1 CDS NTHI0727 NC_007146.2 678202 678387 R hypothetical protein complement(678202..678387) Haemophilus influenzae 86-028NP 3430035 YP_248304.1 CDS sxy NC_007146.2 684668 685321 R competence activator; protein sxy; Similar to: HI0601, TFOX_HAEIN; DNA transformation protein TfoX complement(684668..685321) Haemophilus influenzae 86-028NP 3430041 YP_248305.1 CDS recA NC_007146.2 685693 686757 D recombinase A; recombinase 1; catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 685693..686757 Haemophilus influenzae 86-028NP 3430042 YP_248306.1 CDS recX NC_007146.2 686836 687294 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 686836..687294 Haemophilus influenzae 86-028NP 3430043 YP_248307.1 CDS ccrB NC_007146.2 687291 687677 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(687291..687677) Haemophilus influenzae 86-028NP 3430044 YP_248308.1 CDS NTHI0732 NC_007146.2 687677 688495 R Similar to: HI0597, YIGL_HAEIN; HAD superfamily hydrolase complement(687677..688495) Haemophilus influenzae 86-028NP 3430045 YP_248309.1 CDS argF NC_007146.2 688898 689902 D OTCase; Similar to: HI0596, OTCC_HAEIN; ornithine carbamoyltransferase 688898..689902 Haemophilus influenzae 86-028NP 3430046 YP_248310.1 CDS arcC NC_007146.2 689912 690844 D reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 689912..690844 Haemophilus influenzae 86-028NP 3430047 YP_248311.1 CDS NTHI0735 NC_007146.2 690949 692478 D Similar to: HI0594, YFCC_HAEIN; hypothetical protein 690949..692478 Haemophilus influenzae 86-028NP 3430048 YP_248312.1 CDS pepE NC_007146.2 697114 697818 D alpha-aspartyl dipeptidase; Asp-specific dipeptidase; dipeptidase E; alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 697114..697818 Haemophilus influenzae 86-028NP 3430050 YP_248313.1 CDS NTHI0739 NC_007146.2 697836 699131 D Similar to: HI0585, Y585_HAEIN; C4-dicarboxylate transporter 697836..699131 Haemophilus influenzae 86-028NP 3430051 YP_248314.1 CDS abgA NC_007146.2 699203 700474 D Similar to: HI0584, ABGA_HAEIN; aminobenzoyl-glutamate utilization protein A 699203..700474 Haemophilus influenzae 86-028NP 3430052 YP_248315.1 CDS cpdB NC_007146.2 700567 702540 D periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 700567..702540 Haemophilus influenzae 86-028NP 3430053 YP_248316.1 CDS NTHI0742 NC_007146.2 702649 703056 R HTH-type transcriptional regulator complement(702649..703056) Haemophilus influenzae 86-028NP 3430054 YP_248317.1 CDS NTHI0743 NC_007146.2 703066 703743 R zinc transporter ZitB complement(703066..703743) Haemophilus influenzae 86-028NP 3430055 YP_248318.1 CDS gidA NC_007146.2 704251 706140 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 704251..706140 Haemophilus influenzae 86-028NP 3430056 YP_248319.1 CDS rpsL NC_007146.2 706322 706696 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 706322..706696 Haemophilus influenzae 86-028NP 3430057 YP_248320.1 CDS rpsG NC_007146.2 706853 707323 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 706853..707323 Haemophilus influenzae 86-028NP 3430058 YP_248321.1 CDS fusA NC_007146.2 707407 709509 D EF-G; EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 707407..709509 Haemophilus influenzae 86-028NP 3430059 YP_248322.1 CDS tuf NC_007146.2 709574 710758 D EF-Tu; EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 709574..710758 Haemophilus influenzae 86-028NP 3430060 YP_248323.1 CDS NTHI0749 NC_007146.2 711218 711562 D chloride channel protein 711218..711562 Haemophilus influenzae 86-028NP 3430061 YP_248324.1 CDS NTHI0751 NC_007146.2 711553 711735 D Similar to: HI0633; chloride channel protein 711553..711735 Haemophilus influenzae 86-028NP 3430062 YP_248325.1 CDS dusA NC_007146.2 711738 712721 D Similar to: HI0634, DUSA_HAEIN; tRNA-dihydrouridine synthase A 711738..712721 Haemophilus influenzae 86-028NP 3430063 YP_248326.1 CDS NTHI0754 NC_007146.2 712769 713059 R Similar to: HI0636, Y636_HAEIN; hypothetical protein complement(712769..713059) Haemophilus influenzae 86-028NP 3430064 YP_248327.1 CDS trpS NC_007146.2 713082 714092 R tryptophan--tRNA ligase; TrpRS; catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(713082..714092) Haemophilus influenzae 86-028NP 3430065 YP_248328.1 CDS NTHI0757 NC_007146.2 714215 714832 D HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 714215..714832 Haemophilus influenzae 86-028NP 3430066 YP_248329.1 CDS purB NC_007146.2 714855 716225 D adenylosuccinase; ASL; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 714855..716225 Haemophilus influenzae 86-028NP 3430067 YP_248330.1 CDS rplJ NC_007146.2 716497 716988 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 716497..716988 Haemophilus influenzae 86-028NP 3430068 YP_248331.1 CDS rplL NC_007146.2 717043 717414 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 717043..717414 Haemophilus influenzae 86-028NP 3430069 YP_248332.1 CDS glmU NC_007146.2 717573 718943 D N-acetylglucosamine-1-phosphate uridyltransferase; forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 717573..718943 Haemophilus influenzae 86-028NP 3430070 YP_248333.1 CDS NTHI0763 NC_007146.2 718978 719289 R hypothetical protein complement(718978..719289) Haemophilus influenzae 86-028NP 3430071 YP_248334.1 CDS pldB NC_007146.2 719828 720763 R lecithinase B; Similar to: HI0645, PLDB_HAEIN; lysophospholipase L2 complement(719828..720763) Haemophilus influenzae 86-028NP 3430075 YP_248335.1 CDS asd NC_007146.2 720817 721932 R ASA dehydrogenase; ASADH; catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(720817..721932) Haemophilus influenzae 86-028NP 3430076 YP_248336.1 CDS NTHI0766 NC_007146.2 722098 722814 R Similar to: HI0647, Y647_HAEIN; hypothetical protein complement(722098..722814) Haemophilus influenzae 86-028NP 3430077 YP_248337.1 CDS NTHI0767 NC_007146.2 723006 723662 D Similar to: HI0019, YF71_PASMU; 2-methylthioadenine synthetase 723006..723662 Haemophilus influenzae 86-028NP 3430078 YP_248338.1 CDS mdaB NC_007146.2 723726 724304 R Similar to: HI0648, MDAB_HAEIN; NADPH-quinone reductase, modulator of drug activity B complement(723726..724304) Haemophilus influenzae 86-028NP 3430079 YP_248339.1 CDS rep NC_007146.2 724583 726595 R Similar to: HI0649, REP_HAEIN; ATP-dependent DNA helicase complement(724583..726595) Haemophilus influenzae 86-028NP 3430080 YP_248340.1 CDS NTHI0770 NC_007146.2 726601 726813 R Similar to: HI0650, Y650_HAEIN; periplasmic lipoprotein complement(726601..726813) Haemophilus influenzae 86-028NP 3430081 YP_248341.1 CDS coaD NC_007146.2 726810 727280 R pantetheine-phosphate adenylyltransferase; PPAT; dephospho-CoA pyrophosphorylase; Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(726810..727280) Haemophilus influenzae 86-028NP 3430082 YP_248342.1 CDS kdtA NC_007146.2 727277 728560 R KDO transferase; catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(727277..728560) Haemophilus influenzae 86-028NP 3430083 YP_248343.1 CDS lgtF NC_007146.2 728623 729387 D Similar to: HI0653, Y653_HAEIN; UDP-glucose--lipooligosaccharide glucosyltransferase 728623..729387 Haemophilus influenzae 86-028NP 3430084 YP_248344.1 CDS tag NC_007146.2 729384 729947 R 3-methyladenine-DNA glycosidase; TAG; Similar to: HI0654, 3MGA_HAEIN; DNA-3-methyladenine glycosylase complement(729384..729947) Haemophilus influenzae 86-028NP 3430085 YP_248345.1 CDS NTHI0775 NC_007146.2 730062 730814 R hypothetical protein complement(730062..730814) Haemophilus influenzae 86-028NP 3430086 YP_248346.1 CDS aroE NC_007146.2 730826 731632 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(730826..731632) Haemophilus influenzae 86-028NP 3430087 YP_248347.1 CDS NTHI0777 NC_007146.2 731636 732187 R Similar to: HI0656, YRDC_HAEIN; translation factor SUA5 complement(731636..732187) Haemophilus influenzae 86-028NP 3430088 YP_248348.1 CDS NTHI0778 NC_007146.2 732203 732739 R Similar to: HI0656.1, YRDD_HAEIN; zinc finger domain-containing protein complement(732203..732739) Haemophilus influenzae 86-028NP 3430089 YP_248349.1 CDS NTHI0779 NC_007146.2 732749 734665 R Similar to: HI0658, YHES_HAEIN; ABC transporter ATP-binding protein complement(732749..734665) Haemophilus influenzae 86-028NP 3430090 YP_248350.1 CDS NTHI0780 NC_007146.2 734850 735146 R Similar to: HI0659, Y659_HAEIN; HTH-type transcriptional regulator complement(734850..735146) Haemophilus influenzae 86-028NP 3430091 YP_248351.1 CDS NTHI0781 NC_007146.2 735139 735321 R Similar to: HI0660; hypothetical protein complement(735139..735321) Haemophilus influenzae 86-028NP 3430092 YP_248352.1 CDS hgpB NC_007146.2 735591 738569 R hemoglobin-haptoglobin utilization protein B; Similar to: HI0661, HGPB_HAEIN; hemoglobin-haptoglobin binding protein B complement(735591..738569) Haemophilus influenzae 86-028NP 3430093 YP_248353.1 CDS NTHI0783 NC_007146.2 739300 741045 D Similar to: HI0663, Y663_HAEIN; ABC transporter ATP-binding protein 739300..741045 Haemophilus influenzae 86-028NP 3430094 YP_248354.1 CDS NTHI0785 NC_007146.2 741038 742696 D Similar to: HI0664, Y664_HAEIN; ABC transporter ATP-binding protein 741038..742696 Haemophilus influenzae 86-028NP 3430095 YP_248355.1 CDS NTHI0786 NC_007146.2 742780 743811 R Similar to: HI0665, Y665_HAEIN; hypothetical protein complement(742780..743811) Haemophilus influenzae 86-028NP 3430096 YP_248356.1 CDS NTHI0787 NC_007146.2 743808 744128 R Similar to: HI0666, Y666_HAEIN; hypothetical protein complement(743808..744128) Haemophilus influenzae 86-028NP 3430097 YP_248357.1 CDS NTHI0788 NC_007146.2 744116 744424 R Similar to: HI0666.1, Y66A_HAEIN; HTH-type transcriptional regulator complement(744116..744424) Haemophilus influenzae 86-028NP 3430098 YP_248358.1 CDS glpX NC_007146.2 744629 745630 R D-fructose-1,6-bisphosphate 1-phosphohydrolase class II glpX; FBPase II glpX; type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(744629..745630) Haemophilus influenzae 86-028NP 3430099 YP_248359.1 CDS NTHI0790 NC_007146.2 745792 746010 D Similar to: HI0668; hypothetical protein 745792..746010 Haemophilus influenzae 86-028NP 3430100 YP_248360.1 CDS mioC NC_007146.2 746109 746549 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 746109..746549 Haemophilus influenzae 86-028NP 3430101 YP_248361.1 CDS dtd NC_007146.2 746546 746980 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 746546..746980 Haemophilus influenzae 86-028NP 3430102 YP_248362.1 CDS ispF NC_007146.2 747287 747763 R MECPS; MECDP-synthase; catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(747287..747763) Haemophilus influenzae 86-028NP 3430103 YP_248363.1 CDS ispD NC_007146.2 747760 748437 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(747760..748437) Haemophilus influenzae 86-028NP 3430104 YP_248364.1 CDS ftsB NC_007146.2 748437 748715 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(748437..748715) Haemophilus influenzae 86-028NP 3430105 YP_248365.1 CDS gpt NC_007146.2 748838 749305 R XGPRT; catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase complement(748838..749305) Haemophilus influenzae 86-028NP 3430106 YP_248366.1 CDS pepD NC_007146.2 749416 750870 D Xaa-His dipeptidase; X-His dipeptidase; beta-alanyl-histidine dipeptidase; carnosinase; peptidase D; Similar to: HI0675, PEPD_HAEIN; aminoacyl-histidine dipeptidase 749416..750870 Haemophilus influenzae 86-028NP 3430107 YP_248367.1 CDS xerC NC_007146.2 750923 751810 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC complement(750923..751810) Haemophilus influenzae 86-028NP 3430108 YP_248368.1 CDS NTHI0799 NC_007146.2 751804 752244 R Similar to: HI0677, Y677_HAEIN; hypothetical protein complement(751804..752244) Haemophilus influenzae 86-028NP 3430109 YP_248369.1 CDS tpiA NC_007146.2 752410 753201 D TIM; Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 752410..753201 Haemophilus influenzae 86-028NP 3430110 YP_248370.1 CDS glpE NC_007146.2 753283 753600 R Similar to: HI0679, GLPE_HAEIN; thiosulfate sulfurtransferase complement(753283..753600) Haemophilus influenzae 86-028NP 3430111 YP_248371.1 CDS NTHI0802 NC_007146.2 753601 754479 R Similar to: HI0680, Y680_HAEIN; hypothetical protein complement(753601..754479) Haemophilus influenzae 86-028NP 3430112 YP_248372.1 CDS ilvY NC_007146.2 754511 755389 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(754511..755389) Haemophilus influenzae 86-028NP 3430113 YP_248373.1 CDS ilvC NC_007146.2 756073 757551 D acetohydroxy-acid isomeroreductase; alpha-keto-beta-hydroxylacil reductoisomerase; catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 756073..757551 Haemophilus influenzae 86-028NP 3430114 YP_248374.1 CDS glpC NC_007146.2 757662 758942 R G-3-P dehydrogenase; anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C complement(757662..758942) Haemophilus influenzae 86-028NP 3430115 YP_248375.1 CDS glpB NC_007146.2 758953 760251 R G-3-P dehydrogenase; sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B complement(758953..760251) Haemophilus influenzae 86-028NP 3430116 YP_248376.1 CDS glpA NC_007146.2 760241 761932 R G-3-P dehydrogenase; anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A complement(760241..761932) Haemophilus influenzae 86-028NP 3430117 YP_248377.1 CDS glpT NC_007146.2 762225 763667 D G-3-P transporter; G-3-P permease; Similar to: HI0686, GLPT_HAEIN; glycerol-3-phosphate transporter 762225..763667 Haemophilus influenzae 86-028NP 3430118 YP_248378.1 CDS glpQ NC_007146.2 763771 764865 D glycerophosphodiester phosphodiesterase; surface-exposed lipoprotein D; hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 763771..764865 Haemophilus influenzae 86-028NP 3430119 YP_248379.1 CDS glpF NC_007146.2 765095 765889 D Similar to: HI0690, GLPF_HAEIN; glycerol uptake facilitator protein 765095..765889 Haemophilus influenzae 86-028NP 3430120 YP_248380.1 CDS glpK NC_007146.2 765910 767421 D ATP:glycerol 3-phosphotransferase; glycerokinase; GK; Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 765910..767421 Haemophilus influenzae 86-028NP 3430121 YP_248381.1 CDS gpt2 NC_007146.2 767505 767972 R XGPRT; catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase complement(767505..767972) Haemophilus influenzae 86-028NP 3430122 YP_248382.1 CDS hel NC_007146.2 768257 769081 D lipoprotein E; OMP P4; Similar to: HI0693, HEL_HAEIN; outer membrane protein P4, NADP phosphatase 768257..769081 Haemophilus influenzae 86-028NP 3430124 YP_248383.1 CDS rluE NC_007146.2 769248 769931 D pseudouridylate synthase; Uracil hydrolyase; Similar to: HI0694, RLUE_HAEIN; pseudouridylate synthase 769248..769931 Haemophilus influenzae 86-028NP 3430125 YP_248384.1 CDS NTHI0820 NC_007146.2 771036 774920 R Similar to: HI0696, YTFN_HAEIN; hypothetical protein complement(771036..774920) Haemophilus influenzae 86-028NP 3430127 YP_248385.1 CDS NTHI0821 NC_007146.2 774930 776666 R Similar to: HI0698, YTFM_HAEIN; hypothetical protein complement(774930..776666) Haemophilus influenzae 86-028NP 3430128 YP_248386.1 CDS slyD NC_007146.2 776817 777389 R PPIase; rotamase; Similar to: HI0699, SLYD_HAEIN; FKBP-type peptidylprolyl isomerase complement(776817..777389) Haemophilus influenzae 86-028NP 3430129 YP_248387.1 CDS NTHI0823 NC_007146.2 777467 777889 R Similar to: HI0700, YJGD_HAEIN; hypothetical protein complement(777467..777889) Haemophilus influenzae 86-028NP 3430130 YP_248388.1 CDS truD NC_007146.2 777998 779017 D pseudouridylate synthase; Uracil hydrolyase; catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 777998..779017 Haemophilus influenzae 86-028NP 3430131 YP_248389.1 CDS surE NC_007146.2 779027 779776 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 779027..779776 Haemophilus influenzae 86-028NP 3430132 YP_248390.1 CDS NTHI0826 NC_007146.2 779785 780363 D Similar to: HI0703, Y703_HAEIN; hypothetical protein 779785..780363 Haemophilus influenzae 86-028NP 3430133 YP_248391.1 CDS NTHI0827 NC_007146.2 780372 780557 D Similar to: HI0704, Y704_HAEIN; hypothetical protein 780372..780557 Haemophilus influenzae 86-028NP 3430134 YP_248392.1 CDS lppB NC_007146.2 780592 781809 D Similar to: HI0706, LPPB_HAEIN; lipoprotein 780592..781809 Haemophilus influenzae 86-028NP 3430135 YP_248393.1 CDS tnaA NC_007146.2 782177 783595 D L-tryptophan indole-lyase; TNase; tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 782177..783595 Haemophilus influenzae 86-028NP 3430136 YP_248394.1 CDS tnaB NC_007146.2 783679 784911 D tryptophan permease; Similar to: HI0287, MTR_HAEIN; tryptophan-specific transport protein 783679..784911 Haemophilus influenzae 86-028NP 3430137 YP_248395.1 CDS mutS NC_007146.2 785052 787637 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 785052..787637 Haemophilus influenzae 86-028NP 3430138 YP_248396.1 CDS selA NC_007146.2 787843 789228 D Sec; cysteinyl-tRNA(Sec) selenium transferase; selenocysteine synthase; selenocysteinyl-tRNA(Sec) synthase; catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 787843..789228 Haemophilus influenzae 86-028NP 3430140 YP_248397.1 CDS selB NC_007146.2 789225 791084 D SelB translation factor; Similar to: HI0709, SELB_HAEIN; selenocysteine-specific elongation factor 789225..791084 Haemophilus influenzae 86-028NP 3430141 YP_248398.1 CDS NTHI0837 NC_007146.2 791103 791957 D hypothetical protein 791103..791957 Haemophilus influenzae 86-028NP 3430142 YP_248399.1 CDS relB NC_007146.2 792077 792373 D Similar to: HI0710, Y710_HAEIN; DNA-damage-inducible protein J, negative regulator of translation 792077..792373 Haemophilus influenzae 86-028NP 3430143 YP_248400.1 CDS NTHI0839 NC_007146.2 792373 792681 D Similar to: HI0711, YAFQ_HAEIN; hypothetical protein 792373..792681 Haemophilus influenzae 86-028NP 3430144 YP_248401.1 CDS tig NC_007146.2 796227 797525 D TF; Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 796227..797525 Haemophilus influenzae 86-028NP 3430146 YP_248402.1 CDS clpP NC_007146.2 797648 798229 D endopeptidase Clp; hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 797648..798229 Haemophilus influenzae 86-028NP 3430147 YP_248403.1 CDS clpX NC_007146.2 798239 799474 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 798239..799474 Haemophilus influenzae 86-028NP 3430148 YP_248404.1 CDS secE NC_007146.2 799619 800035 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 799619..800035 Haemophilus influenzae 86-028NP 3430149 YP_248405.1 CDS nusG NC_007146.2 800037 800594 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 800037..800594 Haemophilus influenzae 86-028NP 3430150 YP_248406.1 CDS vacJ NC_007146.2 800745 801497 D Similar to: HI0718, VACJ_HAEIN; VacJ lipoprotein 800745..801497 Haemophilus influenzae 86-028NP 3430151 YP_248407.1 CDS NTHI0851 NC_007146.2 801551 801943 D Similar to: HI0719, YJGF_HAEIN; YjgF family translation initiation inhibitor 801551..801943 Haemophilus influenzae 86-028NP 3430152 YP_248408.1 CDS htpX NC_007146.2 802111 802962 D metalloprotease; heat shock protein HtpX 802111..802962 Haemophilus influenzae 86-028NP 3430153 YP_248409.2 CDS sirA NC_007146.2 803004 803243 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(803004..803243) Haemophilus influenzae 86-028NP 3430154 YP_248410.1 CDS NTHI0854 NC_007146.2 803359 803979 D Similar to: HI0722, YIGZ_HAEIN; hypothetical protein 803359..803979 Haemophilus influenzae 86-028NP 3430155 YP_248411.1 CDS trkH NC_007146.2 803982 805445 D Similar to: HI0723, TRKH_HAEIN; Trk system potassium uptake protein TrkH 803982..805445 Haemophilus influenzae 86-028NP 3430156 YP_248412.1 CDS psiE NC_007146.2 811880 812299 D phosphate-starvation-inducible protein PsiE 811880..812299 Haemophilus influenzae 86-028NP 3430164 YP_248413.1 CDS hemY NC_007146.2 812363 813649 R Similar to: HI0602, HEMY_HAEIN; HemY complement(812363..813649) Haemophilus influenzae 86-028NP 3430165 YP_248414.1 CDS hemX NC_007146.2 813660 814871 R Similar to: HI0603, Y603_HAEIN; uroporphyrin-III C-methyltransferase complement(813660..814871) Haemophilus influenzae 86-028NP 3430166 YP_248415.1 CDS cyaA NC_007146.2 815177 817708 D ATP pyrophosphate-lyase; adenylyl cyclase; catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 815177..817708 Haemophilus influenzae 86-028NP 3430167 YP_248416.1 CDS gpsA NC_007146.2 817782 818789 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 817782..818789 Haemophilus influenzae 86-028NP 3430168 YP_248417.1 CDS cysE NC_007146.2 818806 819609 D SAT; catalyzes the O-acetylation of serine; serine acetyltransferase 818806..819609 Haemophilus influenzae 86-028NP 3430169 YP_248418.1 CDS aroE NC_007146.2 819619 820434 D catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 819619..820434 Haemophilus influenzae 86-028NP 3430170 YP_248419.1 CDS NTHI0863 NC_007146.2 820572 821957 D Similar to: HI0608, Y608_HAEIN; di- and tricarboxylate transporter 820572..821957 Haemophilus influenzae 86-028NP 3430171 YP_248420.1 CDS folD NC_007146.2 822095 822943 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(822095..822943) Haemophilus influenzae 86-028NP 3430172 YP_248421.1 CDS fucP NC_007146.2 823471 824757 R Similar to: HI0610, FUCP_HAEIN; L-fucose permease complement(823471..824757) Haemophilus influenzae 86-028NP 3430175 YP_248422.1 CDS fucA NC_007146.2 824796 825446 R L-fuculose-1-phosphate aldolase; catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(824796..825446) Haemophilus influenzae 86-028NP 3430176 YP_248423.1 CDS fucU NC_007146.2 825466 825900 R Similar to: HI0612, FUCU_HAEIN; fucose operon protein FucU complement(825466..825900) Haemophilus influenzae 86-028NP 3430177 YP_248424.1 CDS fucK NC_007146.2 825914 827326 R L-fuculose kinase; Similar to: HI0613, FUCK_HAEIN; L-fuculokinase complement(825914..827326) Haemophilus influenzae 86-028NP 3430178 YP_248425.2 CDS fucI NC_007146.2 827399 829168 R catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase complement(827399..829168) Haemophilus influenzae 86-028NP 3430179 YP_248426.1 CDS fucR NC_007146.2 829398 830147 R Similar to: HI0615, FUCR_HAEIN; L-fucose operon activator complement(829398..830147) Haemophilus influenzae 86-028NP 3430180 YP_248427.1 CDS hepA NC_007146.2 830346 833117 D transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 830346..833117 Haemophilus influenzae 86-028NP 3430181 YP_248428.1 CDS rluA NC_007146.2 833120 833779 D pseudouridylate synthase; uracil hydrolyase; Similar to: HI0617, RLUA_HAEIN; pseudouridylate synthase 833120..833779 Haemophilus influenzae 86-028NP 3430182 YP_248429.1 CDS glpG NC_007146.2 833806 834384 D Similar to: HI0618, GLPG_HAEIN; hypothetical protein 833806..834384 Haemophilus influenzae 86-028NP 3430183 YP_248430.1 CDS glpR NC_007146.2 834414 835181 D Similar to: HI0619, GLPR_HAEIN; glycerol-3-phosphate regulon repressor 834414..835181 Haemophilus influenzae 86-028NP 3430184 YP_248431.1 CDS metQ NC_007146.2 835483 836304 R Similar to: HI0620, METQ_HAEIN; D-methionine-binding lipoprotein MetQ complement(835483..836304) Haemophilus influenzae 86-028NP 3430185 YP_248432.1 CDS metI NC_007146.2 836343 837032 R Similar to: METI_HAEIN; D-methionine transport system permease protein complement(836343..837032) Haemophilus influenzae 86-028NP 3430186 YP_248433.1 CDS metN NC_007146.2 837022 838059 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(837022..838059) Haemophilus influenzae 86-028NP 3430187 YP_248434.1 CDS NTHI0880 NC_007146.2 838235 838789 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 838235..838789 Haemophilus influenzae 86-028NP 3430188 YP_248435.1 CDS NTHI0881 NC_007146.2 845041 845601 D Similar to: HI0724, Y724_HAEIN; hypothetical protein 845041..845601 Haemophilus influenzae 86-028NP 3430194 YP_248436.1 CDS NTHI0882 NC_007146.2 845605 846045 D Similar to: HI0725, Y725_HAEIN; hypothetical protein 845605..846045 Haemophilus influenzae 86-028NP 3430195 YP_248437.1 CDS narP NC_007146.2 846107 846733 R Similar to: HI0726, NARP_HAEIN; nitrate/nitrite response regulator protein complement(846107..846733) Haemophilus influenzae 86-028NP 3430196 YP_248438.1 CDS lysA NC_007146.2 846939 848186 R DAP decarboxylase; Similar to: HI0727, DCDA_HAEIN; diaminopimelate decarboxylase complement(846939..848186) Haemophilus influenzae 86-028NP 3430197 YP_248439.1 CDS NTHI0885 NC_007146.2 848234 848365 R hypothetical protein complement(848234..848365) Haemophilus influenzae 86-028NP 3430198 YP_248440.1 CDS cyaY NC_007146.2 848448 848753 D defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 848448..848753 Haemophilus influenzae 86-028NP 3430199 YP_248441.1 CDS recQ NC_007146.2 848755 850614 D Similar to: HI0728, RECQ_HAEIN; ATP-dependent DNA helicase RecQ 848755..850614 Haemophilus influenzae 86-028NP 3430200 YP_248442.1 CDS proS NC_007146.2 850699 852417 D proline--tRNA ligase; ProRS; catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 850699..852417 Haemophilus influenzae 86-028NP 3430201 YP_248443.1 CDS ostA NC_007146.2 852505 854853 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(852505..854853) Haemophilus influenzae 86-028NP 3430202 YP_248444.1 CDS sufI NC_007146.2 854976 856385 R Similar to: HI0733, SUFI_HAEIN; hypothetical protein complement(854976..856385) Haemophilus influenzae 86-028NP 3430203 YP_248445.1 CDS plsC NC_007146.2 856387 857109 R 1-AGP acyltransferase; 1-AGPAT; lysophosphatidic acid acyltransferase; LPAAT; Similar to: HI0734, PLSC_HAEIN; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(856387..857109) Haemophilus influenzae 86-028NP 3430204 YP_248446.1 CDS lpxH NC_007146.2 857195 857908 D catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 857195..857908 Haemophilus influenzae 86-028NP 3430205 YP_248447.1 CDS NTHI0893 NC_007146.2 858138 859664 R Similar to: HI0736, Y736_HAEIN; sodium-dependent transporter complement(858138..859664) Haemophilus influenzae 86-028NP 3430206 YP_248448.1 CDS ilvG NC_007146.2 859911 860537 D Similar to: HI0737, Y737_HAEIN; acetolactate synthase isozyme II large subunit 859911..860537 Haemophilus influenzae 86-028NP 3430207 YP_248449.1 CDS ilvD NC_007146.2 860579 862417 D DAD; catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 860579..862417 Haemophilus influenzae 86-028NP 3430208 YP_248450.1 CDS thd1 NC_007146.2 862497 864038 D threonine deaminase; threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 862497..864038 Haemophilus influenzae 86-028NP 3430209 YP_248451.1 CDS dnaE NC_007146.2 864076 867555 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(864076..867555) Haemophilus influenzae 86-028NP 3430210 YP_248452.1 CDS pgmB NC_007146.2 867794 869437 D Similar to: HI0740, Y740_HAEIN; phosphoglucomutase 867794..869437 Haemophilus influenzae 86-028NP 3430211 YP_248453.1 CDS secB NC_007146.2 869604 870113 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(869604..870113) Haemophilus influenzae 86-028NP 3430212 YP_248454.1 CDS NTHI0901 NC_007146.2 870127 870573 R Similar to: HI0744, YIBN_HAEIN; rhodanese-related sulfurtransferase complement(870127..870573) Haemophilus influenzae 86-028NP 3430213 YP_248455.1 CDS dcuB NC_007146.2 870821 872143 D functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 870821..872143 Haemophilus influenzae 86-028NP 3430214 YP_248456.1 CDS ndhA NC_007146.2 872347 873681 D Similar to: HI0747, DHNA_HAEIN; NADH dehydrogenase 872347..873681 Haemophilus influenzae 86-028NP 3430215 YP_248457.1 CDS plsB NC_007146.2 873761 876193 R GPAT; PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(873761..876193) Haemophilus influenzae 86-028NP 3430216 YP_248458.1 CDS lexA NC_007146.2 876442 877071 D Represses a number of genes involved in the response to DNA damage; LexA repressor 876442..877071 Haemophilus influenzae 86-028NP 3430217 YP_248459.1 CDS dapF NC_007146.2 877214 878038 D DAP epimerase; involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 877214..878038 Haemophilus influenzae 86-028NP 3430218 YP_248460.1 CDS tpx NC_007146.2 878258 878755 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(878258..878755) Haemophilus influenzae 86-028NP 3430219 YP_248461.1 CDS purL NC_007146.2 879318 883280 D FGAM synthase; formylglycinamide ribotide amidotransferase; FGARAT; catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 879318..883280 Haemophilus influenzae 86-028NP 3430220 YP_248462.1 CDS lex2B NC_007146.2 883786 884529 D UDP-glucose--lipooligosaccharide glucosyltransferase 883786..884529 Haemophilus influenzae 86-028NP 3430222 YP_248463.1 CDS NTHI0914 NC_007146.2 884590 885432 R Similar to: HI0755, YIBQ_HAEIN; hypothetical protein complement(884590..885432) Haemophilus influenzae 86-028NP 3430223 YP_248464.1 CDS NTHI0915 NC_007146.2 885432 886664 R Similar to: HI0756, YIBP_HAEIN; membrane-bound metallopeptidase complement(885432..886664) Haemophilus influenzae 86-028NP 3430224 YP_248465.1 CDS gpmA NC_007146.2 886840 887523 D phosphoglyceromutase; PGAM; BPG-dependent PGAM; dPGM; 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 886840..887523 Haemophilus influenzae 86-028NP 3430225 YP_248466.1 CDS rpmE NC_007146.2 887601 887813 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(887601..887813) Haemophilus influenzae 86-028NP 3430226 YP_248467.1 CDS mutY NC_007146.2 887990 889126 D Similar to: HI0759, MUTY_HAEIN; A/G-specific adenine glycosylase 887990..889126 Haemophilus influenzae 86-028NP 3430227 YP_248468.1 CDS NTHI0920 NC_007146.2 889104 889376 D Similar to: HI0760, Y760_HAEIN; hypothetical protein 889104..889376 Haemophilus influenzae 86-028NP 3430228 YP_248469.1 CDS mltC NC_007146.2 889391 890464 D Murein hydrolase C; Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 889391..890464 Haemophilus influenzae 86-028NP 3430229 YP_248470.1 CDS NTHI0922 NC_007146.2 891075 891755 R Similar to: HI0762, Y762_HAEIN; diadenosine tetraphosphatase and related serine/threonine protein phosphatase complement(891075..891755) Haemophilus influenzae 86-028NP 3430232 YP_248471.1 CDS nadR NC_007146.2 891752 893017 R NMN adenylyltransferase; ribosylnicotinamide kinase; NMNAT; RNK; catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase complement(891752..893017) Haemophilus influenzae 86-028NP 3430233 YP_248472.1 CDS ribB NC_007146.2 893236 893883 D DHBP synthase; DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 893236..893883 Haemophilus influenzae 86-028NP 3430234 YP_248473.1 CDS lpsA NC_007146.2 893898 894746 D Similar to: HI0765, Y765_HAEIN; lipooligosaccharide glycosyl transferase 893898..894746 Haemophilus influenzae 86-028NP 3430235 YP_248474.1 CDS NTHI0927 NC_007146.2 894795 895277 R Similar to: HI0766, YIBK_HAEIN; RNA methyltransferase complement(894795..895277) Haemophilus influenzae 86-028NP 3430236 YP_248475.1 CDS NTHI0928 NC_007146.2 895287 895868 R Similar to: HI0767, YHHF_HAEIN; hypothetical protein complement(895287..895868) Haemophilus influenzae 86-028NP 3430237 YP_248476.1 CDS ftsY NC_007146.2 895923 897167 D Similar to: HI0768, FTSY_HAEIN; cell division protein FtsY 895923..897167 Haemophilus influenzae 86-028NP 3430238 YP_248477.1 CDS ftsE NC_007146.2 897186 897842 D Similar to: HI0769, FTSE_HAEIN; cell division ATP-binding protein FtsE 897186..897842 Haemophilus influenzae 86-028NP 3430239 YP_248478.1 CDS ftsX NC_007146.2 897852 898784 D ABC transporter, membrane protein; cell division protein FtsX 897852..898784 Haemophilus influenzae 86-028NP 3430240 YP_248479.1 CDS atoB NC_007146.2 898879 900060 R acetoacetyl-CoA thiolase; Similar to: HI0771, ATOB_HAEIN; acetyl-CoA acetyltransferase complement(898879..900060) Haemophilus influenzae 86-028NP 3430241 YP_248480.1 CDS atoE NC_007146.2 900075 901418 R Similar to: HI0772, ATOE_HAEIN; short-chain fatty acids transporter complement(900075..901418) Haemophilus influenzae 86-028NP 3430242 YP_248481.1 CDS atoA NC_007146.2 901421 902086 R Acetyl-CoA:acetoacetate CoA transferase beta subunit; Similar to: HI0773, ATOA_HAEIN; acetate CoA-transferase subunit beta complement(901421..902086) Haemophilus influenzae 86-028NP 3430243 YP_248482.1 CDS atoD NC_007146.2 902097 902750 R Acetyl-CoA:acetoacetate CoA transferase alpha subunit; Similar to: HI0774, ATOD_HAEIN; acetyl-CoA:acetoacetyl-CoA transferase subunit alpha complement(902097..902750) Haemophilus influenzae 86-028NP 3430244 YP_248483.1 CDS NTHI0936 NC_007146.2 902956 903903 D Similar to: HI0775, Y775_HAEIN; HTH-type transcriptional regulator 902956..903903 Haemophilus influenzae 86-028NP 3430245 YP_248484.1 CDS rpsJ NC_007146.2 904140 904451 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 904140..904451 Haemophilus influenzae 86-028NP 3430246 YP_248485.1 CDS rplC NC_007146.2 904468 905094 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 904468..905094 Haemophilus influenzae 86-028NP 3430247 YP_248486.1 CDS rplD NC_007146.2 905110 905712 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 905110..905712 Haemophilus influenzae 86-028NP 3430248 YP_248487.1 CDS rplW NC_007146.2 905709 906008 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 905709..906008 Haemophilus influenzae 86-028NP 3430249 YP_248488.1 CDS rplB NC_007146.2 906026 906847 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 906026..906847 Haemophilus influenzae 86-028NP 3430250 YP_248489.1 CDS rpsS NC_007146.2 906873 907148 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 906873..907148 Haemophilus influenzae 86-028NP 3430251 YP_248490.1 CDS rplV NC_007146.2 907160 907492 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 907160..907492 Haemophilus influenzae 86-028NP 3430252 YP_248491.1 CDS rpsC NC_007146.2 907510 908217 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 907510..908217 Haemophilus influenzae 86-028NP 3430253 YP_248492.1 CDS rplP NC_007146.2 908231 908641 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 908231..908641 Haemophilus influenzae 86-028NP 3430254 YP_248493.1 CDS rpmC NC_007146.2 908641 908832 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 908641..908832 Haemophilus influenzae 86-028NP 3430255 YP_248494.1 CDS rpsQ NC_007146.2 908832 909089 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 908832..909089 Haemophilus influenzae 86-028NP 3430256 YP_248495.1 CDS NTHI0950 NC_007146.2 909479 910102 D Similar to: HI0787, Y787_HAEIN; hypothetical protein 909479..910102 Haemophilus influenzae 86-028NP 3430257 YP_248496.1 CDS rplN NC_007146.2 910383 910754 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 910383..910754 Haemophilus influenzae 86-028NP 3430258 YP_248497.1 CDS rplX NC_007146.2 910765 911076 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 910765..911076 Haemophilus influenzae 86-028NP 3430259 YP_248498.1 CDS rplE NC_007146.2 911094 911633 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 911094..911633 Haemophilus influenzae 86-028NP 3430260 YP_248499.1 CDS rpsN NC_007146.2 911645 911950 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 911645..911950 Haemophilus influenzae 86-028NP 3430261 YP_248500.1 CDS rpsH NC_007146.2 911987 912379 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 911987..912379 Haemophilus influenzae 86-028NP 3430262 YP_248501.1 CDS rplF NC_007146.2 912395 912928 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 912395..912928 Haemophilus influenzae 86-028NP 3430263 YP_248502.1 CDS rplR NC_007146.2 912942 913295 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 912942..913295 Haemophilus influenzae 86-028NP 3430264 YP_248503.1 CDS rpsE NC_007146.2 913310 913810 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 913310..913810 Haemophilus influenzae 86-028NP 3430265 YP_248504.1 CDS rpmD NC_007146.2 913817 913996 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 913817..913996 Haemophilus influenzae 86-028NP 3430266 YP_248505.1 CDS rplO NC_007146.2 914000 914434 D late assembly protein; 50S ribosomal protein L15 914000..914434 Haemophilus influenzae 86-028NP 3430267 YP_248506.1 CDS secY NC_007146.2 914442 915767 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 914442..915767 Haemophilus influenzae 86-028NP 3430268 YP_248507.1 CDS rpsM NC_007146.2 916049 916405 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 916049..916405 Haemophilus influenzae 86-028NP 3430269 YP_248508.1 CDS rpsK NC_007146.2 916421 916810 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 916421..916810 Haemophilus influenzae 86-028NP 3430270 YP_248509.1 CDS rpsD NC_007146.2 916838 917458 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 916838..917458 Haemophilus influenzae 86-028NP 3430271 YP_248510.1 CDS rpoA NC_007146.2 917490 918476 D RNAP alpha subunit; transcriptase alpha chain; RNA polymerase alpha subunit; catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 917490..918476 Haemophilus influenzae 86-028NP 3430272 YP_248511.1 CDS rplQ NC_007146.2 918517 918903 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 918517..918903 Haemophilus influenzae 86-028NP 3430273 YP_248512.1 CDS NTHI0967 NC_007146.2 919030 919626 R Similar to: HI0804, Y804_HAEIN; cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase complement(919030..919626) Haemophilus influenzae 86-028NP 3430274 YP_248513.1 CDS NTHI0970 NC_007146.2 920579 921388 D Similar to: HI0806, Y806_HAEIN; permease 920579..921388 Haemophilus influenzae 86-028NP 3430276 YP_248514.1 CDS dxr NC_007146.2 921420 922613 R DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(921420..922613) Haemophilus influenzae 86-028NP 3430277 YP_248515.1 CDS frr NC_007146.2 922723 923280 R ribosome releasing factor; RRF; Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(922723..923280) Haemophilus influenzae 86-028NP 3430278 YP_248516.1 CDS pckA NC_007146.2 923432 925048 R PEP carboxykinase; phosphoenolpyruvate carboxylase; PEPCK; PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase complement(923432..925048) Haemophilus influenzae 86-028NP 3430279 YP_248517.1 CDS hslO NC_007146.2 925221 926102 R Heat shock protein 33 homolog; HSP33; becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 complement(925221..926102) Haemophilus influenzae 86-028NP 3430280 YP_248518.1 CDS argH NC_007146.2 926247 927620 R arginosuccinase; ASAL; catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(926247..927620) Haemophilus influenzae 86-028NP 3430281 YP_248519.1 CDS galU NC_007146.2 927755 928642 R UDP-glucose pyrophosphorylase; UDPGP; Alpha-D-glucosyl-1-phosphate uridylyltransferase; uridine diphosphoglucose pyrophosphorylase; Similar to: HI0812, GALU_HAEIN; UTP-glucose-1-phosphate uridylyltransferase complement(927755..928642) Haemophilus influenzae 86-028NP 3430282 YP_248520.1 CDS csrA NC_007146.2 928664 928855 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator complement(928664..928855) Haemophilus influenzae 86-028NP 3430283 YP_248521.1 CDS alaS NC_007146.2 928933 931557 R alanine--tRNA ligase; AlaRS; Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(928933..931557) Haemophilus influenzae 86-028NP 3430284 YP_248522.1 CDS uspA NC_007146.2 931744 932169 R Similar to: HI0815, USPA_HAEIN; universal stress protein A complement(931744..932169) Haemophilus influenzae 86-028NP 3430285 YP_248523.1 CDS pepP NC_007146.2 932271 933563 R X-Pro aminopeptidase; aminopeptidase P II; APP-II; aminoacylproline aminopeptidase; Similar to: HI0816, AMPP_HAEIN; Xaa-Pro aminopeptidase complement(932271..933563) Haemophilus influenzae 86-028NP 3430286 YP_248524.1 CDS NTHI0981 NC_007146.2 933575 934123 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(933575..934123) Haemophilus influenzae 86-028NP 3430287 YP_248525.1 CDS galM NC_007146.2 934294 935319 R mutarotase; catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(934294..935319) Haemophilus influenzae 86-028NP 3430288 YP_248526.1 CDS galK NC_007146.2 935326 936522 R galactose kinase; catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(935326..936522) Haemophilus influenzae 86-028NP 3430289 YP_248527.1 CDS galT NC_007146.2 936557 937606 R Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase; catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(936557..937606) Haemophilus influenzae 86-028NP 3430290 YP_248528.1 CDS galR NC_007146.2 937814 938812 D galactose operon repressor; Similar to: HI0821, GALR_HAEIN; HTH-type transcriptional regulator GalR 937814..938812 Haemophilus influenzae 86-028NP 3430291 YP_248529.1 CDS mglB NC_007146.2 938903 939952 D GBP; D-galactose/ D-glucose binding protein; GGBP; Similar to: HI0822, DGAL_HAEIN; D-galactose-binding periplasmic protein 938903..939952 Haemophilus influenzae 86-028NP 3430292 YP_248530.1 CDS mglA NC_007146.2 940018 941538 D with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 940018..941538 Haemophilus influenzae 86-028NP 3430293 YP_248531.1 CDS mglC NC_007146.2 941555 942565 D ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane component 941555..942565 Haemophilus influenzae 86-028NP 3430294 YP_248532.1 CDS NTHI0990 NC_007146.2 942711 943445 D Similar to: HI0825, Y825_HAEIN; hypothetical protein 942711..943445 Haemophilus influenzae 86-028NP 3430295 YP_248533.1 CDS ispZ NC_007146.2 943451 944008 D Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 943451..944008 Haemophilus influenzae 86-028NP 3430296 YP_248534.1 CDS NTHI0992 NC_007146.2 944008 944472 D Similar to: HI0827, YCIA_HAEIN; acyl-CoA thioester hydrolase 944008..944472 Haemophilus influenzae 86-028NP 3430297 YP_248535.1 CDS NTHI0994 NC_007146.2 944489 944785 D unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein 944489..944785 Haemophilus influenzae 86-028NP 3430298 YP_248536.1 CDS slt NC_007146.2 944801 946582 D Similar to: HI0829, SLT_HAEIN; soluble lytic murein transglycosylase 944801..946582 Haemophilus influenzae 86-028NP 3430299 YP_248537.1 CDS trpR NC_007146.2 946620 946925 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 946620..946925 Haemophilus influenzae 86-028NP 3430300 YP_248538.2 CDS mtgA NC_007146.2 946912 947652 D monofunctional TGase; glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 946912..947652 Haemophilus influenzae 86-028NP 3430301 YP_248539.1 CDS frdD NC_007146.2 947758 948102 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(947758..948102) Haemophilus influenzae 86-028NP 3430302 YP_248540.1 CDS frdC NC_007146.2 948115 948525 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(948115..948525) Haemophilus influenzae 86-028NP 3430303 YP_248541.1 CDS frdB NC_007146.2 948536 949306 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(948536..949306) Haemophilus influenzae 86-028NP 3430304 YP_248542.1 CDS frdA NC_007146.2 949299 951098 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(949299..951098) Haemophilus influenzae 86-028NP 3430305 YP_248543.2 CDS genX NC_007146.2 951309 952280 D Lysine--tRNA ligase; LysRS; GX; lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 951309..952280 Haemophilus influenzae 86-028NP 3430306 YP_248544.1 CDS cpxR NC_007146.2 952546 953229 R Similar to: HI0837, CPXR_HAEIN; transcriptional regulatory protein CpxR complement(952546..953229) Haemophilus influenzae 86-028NP 3430307 YP_248545.1 CDS smpA NC_007146.2 953283 953696 R Similar to: HI0838, SMPA_HAEIN; small protein A complement(953283..953696) Haemophilus influenzae 86-028NP 3430308 YP_248546.1 CDS ndpA NC_007146.2 953762 954787 R Similar to: HI0839, NDPA_HAEIN; nucleoid-associated protein NdpA complement(953762..954787) Haemophilus influenzae 86-028NP 3430309 YP_248547.1 CDS NTHI1007 NC_007146.2 954904 955122 D Similar to: HI0840, YEJL_HAEIN; hypothetical protein 954904..955122 Haemophilus influenzae 86-028NP 3430310 YP_248548.1 CDS NTHI1008 NC_007146.2 955124 956881 D Similar to: HI0841, YEJM_HAEIN; hydrolase of alkaline phosphatase superfamily 955124..956881 Haemophilus influenzae 86-028NP 3430311 YP_248549.1 CDS NTHI1009 NC_007146.2 957079 958071 D Similar to: HI0842, Y842_HAEIN; hypothetical protein 957079..958071 Haemophilus influenzae 86-028NP 3430312 YP_248550.1 CDS mobA NC_007146.2 958210 958788 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA complement(958210..958788) Haemophilus influenzae 86-028NP 3430313 YP_248551.1 CDS NTHI1011 NC_007146.2 958853 959119 D Similar to: HI0845, YIHD_HAEIN; hypothetical protein 958853..959119 Haemophilus influenzae 86-028NP 3430314 YP_248552.1 CDS dsbA NC_007146.2 959130 959747 D Similar to: HI0846, DSBA_HAEIN; thiol:disulfide interchange protein DsbA 959130..959747 Haemophilus influenzae 86-028NP 3430315 YP_248553.1 CDS NTHI1013 NC_007146.2 959809 960144 D Similar to: HI0847, YIFE_HAEIN; hypothetical protein 959809..960144 Haemophilus influenzae 86-028NP 3430316 YP_248554.1 CDS trmA NC_007146.2 960288 961379 D tRNA(M-5-U54)-methyltransferase; RUMT; catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 960288..961379 Haemophilus influenzae 86-028NP 3430317 YP_248555.1 CDS NTHI1015 NC_007146.2 961568 962134 D Similar to: HI0849, YHIQ_HAEIN; hypothetical protein 961568..962134 Haemophilus influenzae 86-028NP 3430318 YP_248556.1 CDS NTHI1016 NC_007146.2 962128 962562 D Similar to: HI0850, Y850_HAEIN; positive regulator of sigma E 962128..962562 Haemophilus influenzae 86-028NP 3430319 YP_248557.1 CDS mobB NC_007146.2 962963 963499 D Similar to: HI0851, MOBB_HAEIN; molybdopterin-guanine dinucleotide biosynthesis protein B 962963..963499 Haemophilus influenzae 86-028NP 3430320 YP_248558.1 CDS NTHI1020 NC_007146.2 963496 964887 D Similar to: HI0852, YIEO_HAEIN; hypothetical protein 963496..964887 Haemophilus influenzae 86-028NP 3430321 YP_248559.1 CDS hbpA NC_007146.2 965028 966677 D hemin-binding lipoprotein; Similar to: HI0853, HBPA_HAEIN; heme-binding protein A 965028..966677 Haemophilus influenzae 86-028NP 3430322 YP_248560.1 CDS NTHI1022 NC_007146.2 966853 967614 D Similar to: HI0854, Y854_HAEIN; heme iron utilization protein 966853..967614 Haemophilus influenzae 86-028NP 3430323 YP_248561.1 CDS NTHI1023 NC_007146.2 967751 968098 R Similar to: HI0855, YHAM_HAEIN; hypothetical protein complement(967751..968098) Haemophilus influenzae 86-028NP 3430324 YP_248562.1 CDS polA NC_007146.2 968113 970905 R POL I; has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I complement(968113..970905) Haemophilus influenzae 86-028NP 3430325 YP_248563.1 CDS NTHI1025 NC_007146.2 971054 971356 D Similar to: HI0857, YGFE_HAEIN; hypothetical protein 971054..971356 Haemophilus influenzae 86-028NP 3430326 YP_248564.1 CDS NTHI1027 NC_007146.2 971679 972242 D Similar to: HI0858, YGFA_HAEIN; 5-formyltetrahydrofolate cyclo-ligase 971679..972242 Haemophilus influenzae 86-028NP 3430327 YP_248565.1 CDS clpB NC_007146.2 972370 974940 D Similar to: HI0859, CLPB_HAEIN; ClpB 972370..974940 Haemophilus influenzae 86-028NP 3430328 YP_248566.1 CDS NTHI1029 NC_007146.2 974978 975718 R Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase complement(974978..975718) Haemophilus influenzae 86-028NP 3430329 YP_248567.1 CDS vacB NC_007146.2 975774 978122 R RNase R; VacB; Similar to: HI0861, RNR_HAEIN; ribonuclease R complement(975774..978122) Haemophilus influenzae 86-028NP 3430330 YP_248568.1 CDS NTHI1031 NC_007146.2 978314 979021 R Similar to: HI0862, YHHQ_HAEIN; hypothetical protein complement(978314..979021) Haemophilus influenzae 86-028NP 3430331 YP_248569.2 CDS pdxH NC_007146.2 979214 979846 D PNP/PMP oxidase; PNPOx; catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 979214..979846 Haemophilus influenzae 86-028NP 3430332 YP_248570.1 CDS typA NC_007146.2 979933 981783 R Similar to: HI0864, TYPA_HAEIN; GTP-binding protein TypA complement(979933..981783) Haemophilus influenzae 86-028NP 3430333 YP_248571.1 CDS lic3A2 NC_007146.2 981910 982890 R Similar to: HI0352, Y352_HAEIN; CMP-neu5Ac--lipooligosaccharide alpha 2-3 sialyltransferase complement(981910..982890) Haemophilus influenzae 86-028NP 3430334 YP_248572.1 CDS glnA NC_007146.2 983047 984459 D glutamate--ammonia ligase; Similar to: HI0865, GLNA_HAEIN; glutamine synthetase 983047..984459 Haemophilus influenzae 86-028NP 3430335 YP_248573.1 CDS rmlB NC_007146.2 984546 985589 D Similar to: HI0873, RFBB_NEIMB; dTDP-glucose 4,6-dehydratase 984546..985589 Haemophilus influenzae 86-028NP 3430336 YP_248574.1 CDS pepB NC_007146.2 985666 986970 D catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase 985666..986970 Haemophilus influenzae 86-028NP 3430337 YP_248575.1 CDS ndk NC_007146.2 986977 987402 D NDK; NDP kinase; nucleoside-2-P kinase; catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 986977..987402 Haemophilus influenzae 86-028NP 3430338 YP_248576.1 CDS obgE NC_007146.2 987472 988644 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(987472..988644) Haemophilus influenzae 86-028NP 3430339 YP_248577.1 CDS NTHI1041 NC_007146.2 988672 989592 R Similar to: HI0878, YHBE_HAEIN; transport protein complement(988672..989592) Haemophilus influenzae 86-028NP 3430340 YP_248578.1 CDS rpmA NC_007146.2 989672 989929 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(989672..989929) Haemophilus influenzae 86-028NP 3430341 YP_248579.1 CDS rplU NC_007146.2 989950 990261 R Similar to: HI0880, RL21_HAEIN; 50S ribosomal protein L21 complement(989950..990261) Haemophilus influenzae 86-028NP 3430342 YP_248580.1 CDS ispB NC_007146.2 990474 991463 D octaprenyl pyrophosphate synthetase; OPP synthetase; Similar to: HI0881, ISPB_HAEIN; octaprenyl-diphosphate synthase 990474..991463 Haemophilus influenzae 86-028NP 3430343 YP_248581.1 CDS NTHI1045 NC_007146.2 991514 992251 D Similar to: HI0882, Y882_HAEIN; hypothetical protein 991514..992251 Haemophilus influenzae 86-028NP 3430344 YP_248582.1 CDS NTHI1046 NC_007146.2 992311 993681 R Similar to: HI0883, Y883_HAEIN; Na+/alanine symporter complement(992311..993681) Haemophilus influenzae 86-028NP 3430345 YP_248583.1 CDS arcA NC_007146.2 994081 994791 R Similar to: HI0884, ARCA_HAEIN; two-component response regulator complement(994081..994791) Haemophilus influenzae 86-028NP 3430346 YP_248584.1 CDS dipZ NC_007146.2 994983 996722 D protein-disulfide reductase; disulfide reductase; C-type cytochrome biogenesis protein CycZ; two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 994983..996722 Haemophilus influenzae 86-028NP 3430347 YP_248585.1 CDS NTHI1049 NC_007146.2 996839 997243 D Similar to: HI0886, Y886_HAEIN; hypothetical protein 996839..997243 Haemophilus influenzae 86-028NP 3430348 YP_248586.1 CDS purH NC_007146.2 997432 999030 D AICAR transformylase; inosinicase; IMP synthetase; ATIC; involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 997432..999030 Haemophilus influenzae 86-028NP 3430349 YP_248587.1 CDS purD NC_007146.2 999126 1000415 D GARS; glycinamide ribonucleotide synthetase; phosphoribosylglycinamide synthetase; catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 999126..1000415 Haemophilus influenzae 86-028NP 3430350 YP_248588.1 CDS glyA NC_007146.2 1002261 1003526 D Serine methylase; SHMT; catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1002261..1003526 Haemophilus influenzae 86-028NP 3430352 YP_248589.1 CDS coaE NC_007146.2 1003585 1004217 D dephosphocoenzyme A kinase; catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1003585..1004217 Haemophilus influenzae 86-028NP 3430353 YP_248590.1 CDS NTHI1056 NC_007146.2 1004210 1004416 D Similar to: HI0891, Y891_HAEIN; zinc-binding protein 1004210..1004416 Haemophilus influenzae 86-028NP 3430354 YP_248591.1 CDS rhlB NC_007146.2 1004525 1005781 D enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 1004525..1005781 Haemophilus influenzae 86-028NP 3430355 YP_248592.1 CDS NTHI1058 NC_007146.2 1006023 1006586 D Similar to: HI0893, Y893_HAEIN; transcriptional regulator 1006023..1006586 Haemophilus influenzae 86-028NP 3430356 YP_248593.1 CDS NTHI1059 NC_007146.2 1006618 1007814 D Similar to: HI0894, Y894_HAEIN; membrane-fusion protein 1006618..1007814 Haemophilus influenzae 86-028NP 3430357 YP_248594.1 CDS NTHI1060 NC_007146.2 1007814 1010912 D Similar to: HI0895, Y895_HAEIN; cation/multidrug efflux pump 1007814..1010912 Haemophilus influenzae 86-028NP 3430358 YP_248595.1 CDS NTHI1061 NC_007146.2 1011447 1011917 D Similar to: HI0896, Y896_HAEIN; cell division protein 1011447..1011917 Haemophilus influenzae 86-028NP 3430359 YP_248596.1 CDS emrB NC_007146.2 1011930 1013462 R Similar to: HI0897, EMRB_HAEIN; multidrug resistance protein complement(1011930..1013462) Haemophilus influenzae 86-028NP 3430360 YP_248597.1 CDS emrA NC_007146.2 1013472 1014644 R Similar to: HI0898, EMRA_HAEIN; multidrug resistance protein A complement(1013472..1014644) Haemophilus influenzae 86-028NP 3430361 YP_248598.1 CDS folA NC_007146.2 1014817 1015299 R Similar to: HI0899, DYR_HAEIN; dihydrofolate reductase complement(1014817..1015299) Haemophilus influenzae 86-028NP 3430362 YP_248599.1 CDS proB NC_007146.2 1015401 1016507 D Gamma-glutamyl kinase; GK; catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1015401..1016507 Haemophilus influenzae 86-028NP 3430363 YP_248600.1 CDS nudH NC_007146.2 1016588 1017178 D di; hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1016588..1017178 Haemophilus influenzae 86-028NP 3430364 YP_248601.1 CDS NTHI1069 NC_007146.2 1017178 1017972 D Similar to: HI0902, Y902_HAEIN; permease 1017178..1017972 Haemophilus influenzae 86-028NP 3430365 YP_248602.1 CDS lgt NC_007146.2 1017981 1018787 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1017981..1018787 Haemophilus influenzae 86-028NP 3430366 YP_248603.1 CDS thyA NC_007146.2 1018797 1019648 D TS; TSase; ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1018797..1019648 Haemophilus influenzae 86-028NP 3430367 YP_248604.1 CDS NTHI1073 NC_007146.2 1019648 1020169 D Similar to: HI0906, YFHC_HAEIN; hypothetical protein 1019648..1020169 Haemophilus influenzae 86-028NP 3430368 YP_248605.1 CDS NTHI1074 NC_007146.2 1020197 1020511 R Similar to: HI0907, Y907_HAEIN; hypothetical protein complement(1020197..1020511) Haemophilus influenzae 86-028NP 3430369 YP_248606.1 CDS NTHI1075 NC_007146.2 1020582 1020893 D Similar to: HI0908, Y908_HAEIN; hypothetical protein 1020582..1020893 Haemophilus influenzae 86-028NP 3430370 YP_248607.1 CDS secA NC_007146.2 1021018 1023723 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1021018..1023723 Haemophilus influenzae 86-028NP 3430371 YP_248608.1 CDS mutT NC_007146.2 1023788 1024198 D 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase; Similar to: HI0910, MUTT_HAEIN; mutator protein MutT 1023788..1024198 Haemophilus influenzae 86-028NP 3430372 YP_248609.1 CDS kefB NC_007146.2 1024307 1026163 D K(+)/H(+) antiporter; Similar to: HI0911, KEFX_HAEIN; glutathione-regulated potassium-efflux system protein 1024307..1026163 Haemophilus influenzae 86-028NP 3430373 YP_248610.1 CDS NTHI1079 NC_007146.2 1026264 1027028 D Similar to: HI0912, Y912_HAEIN; hypothetical protein 1026264..1027028 Haemophilus influenzae 86-028NP 3430374 YP_248611.2 CDS rpsB NC_007146.2 1027206 1027928 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1027206..1027928 Haemophilus influenzae 86-028NP 3430375 YP_248612.1 CDS tsf NC_007146.2 1028062 1028913 D EF-Ts; EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1028062..1028913 Haemophilus influenzae 86-028NP 3430376 YP_248613.1 CDS lpxD NC_007146.2 1029093 1030118 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(1029093..1030118) Haemophilus influenzae 86-028NP 3430377 YP_248614.1 CDS omp26 NC_007146.2 1030131 1030724 R Similar to: HI0916, OM26_HAEIN; hypothetical protein complement(1030131..1030724) Haemophilus influenzae 86-028NP 3430378 YP_248615.1 CDS NTHI1084 NC_007146.2 1030832 1033234 R Outer membrane protein D15; Similar to: HI0917, D152_HAEIN; protective surface antigen D15 complement(1030832..1033234) Haemophilus influenzae 86-028NP 3430379 YP_248616.1 CDS NTHI1085 NC_007146.2 1033254 1034585 R Similar to: HI0918, YAEL_HAEIN; zinc metalloprotease complement(1033254..1034585) Haemophilus influenzae 86-028NP 3430380 YP_248617.1 CDS cdsA NC_007146.2 1034595 1035461 R CDP-diglyceride synthetase; CDP-diglyceride pyrophosphorylase; CDP-diacylglycerol synthase; CDS; CTP:phosphatidate cytidylyltransferase; CDP-DAG synthase; CDP-DG synthetase; Similar to: HI0919, CDSA_HAEIN; phosphatidate cytidylyltransferase complement(1034595..1035461) Haemophilus influenzae 86-028NP 3430381 YP_248618.1 CDS uppS NC_007146.2 1035479 1036198 R UPP synthetase; Di-trans-poly-cis-decaprenylcistransferase; undecaprenyl diphosphate synthase; UDS; Similar to: HI0920, UPPS_HAEIN; undecaprenyl pyrophosphate synthetase complement(1035479..1036198) Haemophilus influenzae 86-028NP 3430382 YP_248619.1 CDS leuS NC_007146.2 1036447 1039032 D leucine--tRNA ligase; LeuRS; leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1036447..1039032 Haemophilus influenzae 86-028NP 3430383 YP_248620.1 CDS NTHI1091 NC_007146.2 1039082 1039630 D Similar to: HI0922, Y922_HAEIN; lipoprotein 1039082..1039630 Haemophilus influenzae 86-028NP 3430384 YP_248621.1 CDS holA NC_007146.2 1039630 1040664 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1039630..1040664 Haemophilus influenzae 86-028NP 3430385 YP_248622.1 CDS glyS NC_007146.2 1040898 1043066 R glycine--tRNA ligase beta chain; GlyRS; glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(1040898..1043066) Haemophilus influenzae 86-028NP 3430387 YP_248623.1 CDS NTHI1094 NC_007146.2 1043112 1043528 R hypothetical protein complement(1043112..1043528) Haemophilus influenzae 86-028NP 3430388 YP_248624.1 CDS NTHI1095 NC_007146.2 1043668 1044033 R Similar to: HI0925, Y925_HAEIN; hypothetical protein complement(1043668..1044033) Haemophilus influenzae 86-028NP 3430389 YP_248625.1 CDS NTHI1097 NC_007146.2 1044063 1044323 R Similar to: HI0926, Y926_HAEIN; glutaredoxin-like protein complement(1044063..1044323) Haemophilus influenzae 86-028NP 3430390 YP_248626.1 CDS glyQ NC_007146.2 1044382 1045290 R glycine--tRNA ligase alpha chain; GlyRS; glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(1044382..1045290) Haemophilus influenzae 86-028NP 3430391 YP_248627.1 CDS hktE NC_007146.2 1045553 1047079 D Similar to: HI0928, CATA_HAEIN; catalase 1045553..1047079 Haemophilus influenzae 86-028NP 3430392 YP_248628.1 CDS NTHI1100 NC_007146.2 1047311 1048492 R Similar to: HI0929, YGIC_HAEIN; hypothetical protein complement(1047311..1048492) Haemophilus influenzae 86-028NP 3430393 YP_248629.1 CDS NTHI1101 NC_007146.2 1048493 1049074 R Similar to: HI0930, Y930_HAEIN; hypothetical protein complement(1048493..1049074) Haemophilus influenzae 86-028NP 3430394 YP_248630.1 CDS NTHI1102 NC_007146.2 1049087 1049539 R Similar to: HI0931, Y931_HAEIN; hypothetical protein complement(1049087..1049539) Haemophilus influenzae 86-028NP 3430395 YP_248631.1 CDS eno NC_007146.2 1049590 1050900 R 2-phosphoglycerate dehydratase; 2-phospho-D-glycerate hydro-lyase; enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(1049590..1050900) Haemophilus influenzae 86-028NP 3430396 YP_248632.1 CDS NTHI1104 NC_007146.2 1051021 1052226 R Similar to: HI0933, YHIN_HAEIN; hypothetical protein complement(1051021..1052226) Haemophilus influenzae 86-028NP 3430397 YP_248633.1 CDS nrfF NC_007146.2 1052223 1053365 R Similar to: HI0934, NRFF_HAEIN; formate-dependent nitrite reductase complex nrfFG subunit complement(1052223..1053365) Haemophilus influenzae 86-028NP 3430398 YP_248634.1 CDS dsbE2 NC_007146.2 1053362 1053892 R cytochrome c biogenesis protein nrfX; Similar to: HI0935, NRFX_HAEIN; thiol:disulfide interchange protein DsbE complement(1053362..1053892) Haemophilus influenzae 86-028NP 3430399 YP_248635.1 CDS nrfE NC_007146.2 1053892 1055799 R Similar to: HI0936, NRFE_HAEIN; cytochrome c-type biogenesis protein NrfE complement(1053892..1055799) Haemophilus influenzae 86-028NP 3430400 YP_248636.1 CDS suhB NC_007146.2 1055908 1056720 R IMPase; inositol-1-phosphatase; I-1-Pase; Similar to: HI0937, SUHB_HAEIN; inositol monophosphatase complement(1055908..1056720) Haemophilus influenzae 86-028NP 3430401 YP_248637.1 CDS NTHI1109 NC_007146.2 1056920 1057432 D Similar to: HI0938, Y938_HAEIN; hypothetical protein 1056920..1057432 Haemophilus influenzae 86-028NP 3430402 YP_248638.1 CDS NTHI1110 NC_007146.2 1057432 1058151 D Similar to: HI0939, Y939_HAEIN; hypothetical protein 1057432..1058151 Haemophilus influenzae 86-028NP 3430403 YP_248639.1 CDS NTHI1111 NC_007146.2 1058148 1058831 D Similar to: HI0940, Y940_HAEIN; hypothetical protein 1058148..1058831 Haemophilus influenzae 86-028NP 3430404 YP_248640.1 CDS NTHI1112 NC_007146.2 1058836 1059111 D Similar to: HI0941, Y941_HAEIN; hypothetical protein 1058836..1059111 Haemophilus influenzae 86-028NP 3430405 YP_248641.1 CDS recC NC_007146.2 1059157 1062522 D Similar to: HI0942, EX5C_HAEIN; exodeoxyribonuclease V subunit gamma 1059157..1062522 Haemophilus influenzae 86-028NP 3430406 YP_248642.1 CDS nrdR NC_007146.2 1062577 1063026 D Similar to: HI0943, YBAD_HAEIN; Zn-ribbon and ATP-cone domains; transcriptional regulator NrdR 1062577..1063026 Haemophilus influenzae 86-028NP 3430407 YP_248643.1 CDS ribD NC_007146.2 1063029 1064147 D riboflavin-specific deaminase; HTP reductase; Similar to: HI0944, RIBD_HAEIN; riboflavin biosynthesis protein RibD 1063029..1064147 Haemophilus influenzae 86-028NP 3430408 YP_248644.1 CDS degS NC_007146.2 1064148 1065170 D Similar to: HI0945, DEGS_HAEIN; protease DegS 1064148..1065170 Haemophilus influenzae 86-028NP 3430409 YP_248645.1 CDS mutM NC_007146.2 1065244 1066059 R FAPY-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(1065244..1066059) Haemophilus influenzae 86-028NP 3430410 YP_248646.1 CDS ddc NC_007146.2 1066291 1067826 R DABA decarboxylase; DABA-DC; Similar to: HI0946.1, DDC_HAEIN; L-2,4-diaminobutyrate decarboxylase complement(1066291..1067826) Haemophilus influenzae 86-028NP 3430411 YP_248647.1 CDS NTHI1120 NC_007146.2 1067846 1068244 R Similar to: HI0947, Y947_HAEIN; nucleic acid-binding protein complement(1067846..1068244) Haemophilus influenzae 86-028NP 3430412 YP_248648.1 CDS NTHI1121 NC_007146.2 1068244 1068477 R Similar to: HI0948, Y948_HAEIN; hypothetical protein complement(1068244..1068477) Haemophilus influenzae 86-028NP 3430413 YP_248649.1 CDS dat NC_007146.2 1068624 1069988 R L-diaminobutyric acid transaminase; diaminobutyrate transaminase; DABA aminotransferase; DABA-AT; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase complement(1068624..1069988) Haemophilus influenzae 86-028NP 3430414 YP_248650.1 CDS rpmG NC_007146.2 1070335 1070505 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(1070335..1070505) Haemophilus influenzae 86-028NP 3430415 YP_248651.1 CDS rpmB NC_007146.2 1070517 1070753 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(1070517..1070753) Haemophilus influenzae 86-028NP 3430416 YP_248652.1 CDS radC NC_007146.2 1070967 1071671 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(1070967..1071671) Haemophilus influenzae 86-028NP 3430417 YP_248653.1 CDS dfp NC_007146.2 1071795 1072997 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 1071795..1072997 Haemophilus influenzae 86-028NP 3430418 YP_248654.1 CDS dut NC_007146.2 1073045 1073500 D dUTPase; dUTP pyrophosphatase; catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 1073045..1073500 Haemophilus influenzae 86-028NP 3430419 YP_248655.1 CDS slmA NC_007146.2 1073504 1074160 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 1073504..1074160 Haemophilus influenzae 86-028NP 3430420 YP_248656.1 CDS NTHI1129 NC_007146.2 1074182 1074433 D Similar to: Y956_HAEIN; hypothetical protein 1074182..1074433 Haemophilus influenzae 86-028NP 3430421 YP_248657.1 CDS crp NC_007146.2 1074418 1075092 D cAMP receptor protein; cAMP-regulatory protein; complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 1074418..1075092 Haemophilus influenzae 86-028NP 3430422 YP_248658.1 CDS rumB NC_007146.2 1075457 1076635 R RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase complement(1075457..1076635) Haemophilus influenzae 86-028NP 3430423 YP_248659.1 CDS nagZ NC_007146.2 1076628 1077683 R N-acetyl-beta-glucosaminidase; Beta-N-acetylhexosaminidase; hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase complement(1076628..1077683) Haemophilus influenzae 86-028NP 3430424 YP_248660.1 CDS NTHI1133 NC_007146.2 1077687 1078037 R Similar to: HI0960, Y960_HAEIN; periplasmic lipoprotein complement(1077687..1078037) Haemophilus influenzae 86-028NP 3430425 YP_248661.1 CDS NTHI1134 NC_007146.2 1078037 1078429 R Similar to: HI0961, YCFF_HAEIN; HIT-like protein complement(1078037..1078429) Haemophilus influenzae 86-028NP 3430426 YP_248662.1 CDS ileS NC_007146.2 1078504 1081329 R isoleucine--tRNA ligase; IleRS; IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(1078504..1081329) Haemophilus influenzae 86-028NP 3430427 YP_248663.1 CDS ribF NC_007146.2 1081358 1082296 R flavokinase; FAD pyrophosphorylase; FAD synthetase; catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(1081358..1082296) Haemophilus influenzae 86-028NP 3430428 YP_248664.1 CDS mviN NC_007146.2 1082331 1083863 R Similar to: HI0964, MVIN_HAEIN; virulence factor MviN complement(1082331..1083863) Haemophilus influenzae 86-028NP 3430429 YP_248665.2 CDS rpsT NC_007146.2 1084172 1084435 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1084172..1084435 Haemophilus influenzae 86-028NP 3430430 YP_248666.1 CDS NTHI1140 NC_007146.2 1084507 1085073 R Similar to: HI0966, Y966_HAEIN; hypothetical protein complement(1084507..1085073) Haemophilus influenzae 86-028NP 3430431 YP_248667.1 CDS menB NC_007146.2 1085219 1086076 D dihydroxynaphthoic acid synthetase; DHNA synthetase; catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 1085219..1086076 Haemophilus influenzae 86-028NP 3430432 YP_248668.1 CDS menC NC_007146.2 1086246 1087235 D OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; O-succinylbenzoic acid synthase; catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 1086246..1087235 Haemophilus influenzae 86-028NP 3430433 YP_248669.1 CDS aroQ NC_007146.2 1087292 1087741 D 3-dehydroquinase; Type II DHQase; catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 1087292..1087741 Haemophilus influenzae 86-028NP 3430434 YP_248670.1 CDS accB NC_007146.2 1087895 1088362 D BCCP; composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 1087895..1088362 Haemophilus influenzae 86-028NP 3430435 YP_248671.1 CDS accC NC_007146.2 1088539 1089885 D A subunit of acetyl-CoA carboxylase; an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 1088539..1089885 Haemophilus influenzae 86-028NP 3430436 YP_248672.1 CDS NTHI1146 NC_007146.2 1090090 1090347 D Similar to: HI0974.1, YHDT_HAEIN; hypothetical protein 1090090..1090347 Haemophilus influenzae 86-028NP 3430437 YP_248673.1 CDS panF NC_007146.2 1090344 1091798 D pantothenate permease; mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 1090344..1091798 Haemophilus influenzae 86-028NP 3430438 YP_248674.1 CDS NTHI1148 NC_007146.2 1091919 1092791 D Similar to: HI0976.1, Y97X_HAEIN; hypothetical protein 1091919..1092791 Haemophilus influenzae 86-028NP 3430439 YP_248675.1 CDS prmA NC_007146.2 1092826 1093713 D L11 Mtase; methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 1092826..1093713 Haemophilus influenzae 86-028NP 3430440 YP_248676.1 CDS dusB NC_007146.2 1093860 1094840 D Similar to: HI0979, DUSB_HAEIN; tRNA-dihydrouridine synthase B 1093860..1094840 Haemophilus influenzae 86-028NP 3430441 YP_248677.1 CDS fis NC_007146.2 1094834 1095133 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; Fis family transcriptional regulator 1094834..1095133 Haemophilus influenzae 86-028NP 3430442 YP_248678.1 CDS smpB NC_007146.2 1095234 1095719 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(1095234..1095719) Haemophilus influenzae 86-028NP 3430443 YP_248679.1 CDS pfkA NC_007146.2 1095958 1096923 R phosphofructokinase; phosphohexokinase; catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(1095958..1096923) Haemophilus influenzae 86-028NP 3430444 YP_248680.1 CDS NTHI1155 NC_007146.2 1097019 1097600 R Similar to: HI0983, Y983_HAEIN; hypothetical protein complement(1097019..1097600) Haemophilus influenzae 86-028NP 3430445 YP_248681.1 CDS NTHI1156 NC_007146.2 1097593 1098444 R Similar to: HI0984, Y984_HAEIN; hypothetical protein complement(1097593..1098444) Haemophilus influenzae 86-028NP 3430446 YP_248682.1 CDS smf NC_007146.2 1098422 1099543 R DNA processing chain A; Similar to: HI0985, SMF_HAEIN; hypothetical protein complement(1098422..1099543) Haemophilus influenzae 86-028NP 3430447 YP_248683.1 CDS leuA NC_007146.2 1100087 1101634 D Alpha-isopropylmalate synthase; Alpha-IPM synthetase; catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 1100087..1101634 Haemophilus influenzae 86-028NP 3430448 YP_248684.1 CDS leuB NC_007146.2 1101797 1102873 D beta-IPM dehydrogenase; IMDH; 3-IPM-DH; catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1101797..1102873 Haemophilus influenzae 86-028NP 3430449 YP_248685.1 CDS leuC NC_007146.2 1103050 1104459 D isopropylmalate isomerase; alpha-IPM isomerase; IPMI; dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1103050..1104459 Haemophilus influenzae 86-028NP 3430450 YP_248686.1 CDS leuD NC_007146.2 1104484 1105086 D isopropylmalate isomerase; alpha-IPM isomerase; IPMI; catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 1104484..1105086 Haemophilus influenzae 86-028NP 3430451 YP_248687.1 CDS iga1 NC_007146.2 1105200 1110584 R IgA protease; Similar to: HI0990, IGA_NEIGO; IgA-specific serine endopeptidase complement(1105200..1110584) Haemophilus influenzae 86-028NP 3430452 YP_248688.1 CDS recF NC_007146.2 1110811 1111890 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(1110811..1111890) Haemophilus influenzae 86-028NP 3430453 YP_248689.1 CDS dnaN NC_007146.2 1111892 1112992 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(1111892..1112992) Haemophilus influenzae 86-028NP 3430454 YP_248690.1 CDS dnaA NC_007146.2 1113185 1114549 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA complement(1113185..1114549) Haemophilus influenzae 86-028NP 3430455 YP_248691.1 CDS tbp1 NC_007146.2 1114736 1117474 R Similar to: HI0994, TBP1_HAEIN; transferrin-binding protein 1 complement(1114736..1117474) Haemophilus influenzae 86-028NP 3430456 YP_248692.1 CDS tbp2 NC_007146.2 1117519 1119411 R Similar to: HI0995, TBP2_HAEIN; transferrin-binding protein 2 complement(1117519..1119411) Haemophilus influenzae 86-028NP 3430457 YP_248693.1 CDS NTHI1171 NC_007146.2 1119508 1120968 D Similar to: HI0997, Y997_HAEIN; hypothetical protein 1119508..1120968 Haemophilus influenzae 86-028NP 3430458 YP_248694.1 CDS rpmH NC_007146.2 1121144 1121278 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1121144..1121278 Haemophilus influenzae 86-028NP 3430459 YP_248695.1 CDS rnpA NC_007146.2 1121291 1121650 D RNaseP protein; RNase P protein; protein C5; protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1121291..1121650 Haemophilus influenzae 86-028NP 3430460 YP_248696.1 CDS NTHI1174 NC_007146.2 1121614 1121874 D Similar to: HI1000, YA00_HAEIN; hypothetical protein 1121614..1121874 Haemophilus influenzae 86-028NP 3430461 YP_248697.1 CDS yidC NC_007146.2 1121874 1123499 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 1121874..1123499 Haemophilus influenzae 86-028NP 3430462 YP_248698.1 CDS trmE NC_007146.2 1124370 1125728 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1124370..1125728 Haemophilus influenzae 86-028NP 3430463 YP_248699.1 CDS ppiD NC_007146.2 1125917 1127785 D PPIase D; rotamase D; Similar to: HI1004, PPID_HAEIN; peptidyl-prolyl cis-trans isomerase D 1125917..1127785 Haemophilus influenzae 86-028NP 3430464 YP_248700.1 CDS NTHI1180 NC_007146.2 1127873 1129432 D Similar to: HI1005, YA05_HAEIN; PE--lipooligosaccharide phosphorylethanolamine transferase 1127873..1129432 Haemophilus influenzae 86-028NP 3430465 YP_248701.1 CDS lspA NC_007146.2 1129502 1130017 D prolipoprotein signal peptidase; signal peptidase II; SPase II; lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1129502..1130017 Haemophilus influenzae 86-028NP 3430466 YP_248702.1 CDS ispH NC_007146.2 1130014 1130958 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1130014..1130958 Haemophilus influenzae 86-028NP 3430467 YP_248703.1 CDS NTHI1183 NC_007146.2 1131127 1131474 D Similar to: HI1008, YBAV_HAEIN; hypothetical protein 1131127..1131474 Haemophilus influenzae 86-028NP 3430468 YP_248704.1 CDS tbpA NC_007146.2 1131721 1132719 D Similar to: HI1019, TBPA_HAEIN; thiamine-binding periplasmic protein 1131721..1132719 Haemophilus influenzae 86-028NP 3430469 YP_248705.1 CDS thiP NC_007146.2 1132724 1134340 D permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 1132724..1134340 Haemophilus influenzae 86-028NP 3430470 YP_248706.1 CDS thiQ NC_007146.2 1134318 1134971 D Similar to: HI1021, THIQ_HAEIN; thiamine transport ATP-binding protein 1134318..1134971 Haemophilus influenzae 86-028NP 3430471 YP_248707.1 CDS bioB NC_007146.2 1135084 1136085 D biotin synthetase; Similar to: HI1022, BIOB_HAEIN; biotin synthase 1135084..1136085 Haemophilus influenzae 86-028NP 3430472 YP_248708.1 CDS tktA NC_007146.2 1136210 1138207 R TK; catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(1136210..1138207) Haemophilus influenzae 86-028NP 3430473 YP_248709.1 CDS serB NC_007146.2 1138588 1139532 D PSP; O-phosphoserine phosphohydrolase; PSPase; catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 1138588..1139532 Haemophilus influenzae 86-028NP 3430474 YP_248710.1 CDS NTHI1194 NC_007146.2 1139550 1140041 D nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 1139550..1140041 Haemophilus influenzae 86-028NP 3430475 YP_248711.1 CDS corA NC_007146.2 1140337 1141284 D responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 1140337..1141284 Haemophilus influenzae 86-028NP 3430476 YP_248712.1 CDS NTHI1196 NC_007146.2 1141275 1141829 D Similar to: HI1036, YGGT_HAEIN; hypothetical protein 1141275..1141829 Haemophilus influenzae 86-028NP 3430477 YP_248713.1 CDS NTHI1197 NC_007146.2 1142009 1142893 R Similar to: HI1037, YAFJ_HAEIN; hypothetical protein complement(1142009..1142893) Haemophilus influenzae 86-028NP 3430478 YP_248714.1 CDS NTHI1198 NC_007146.2 1143050 1143577 R hypothetical protein complement(1143050..1143577) Haemophilus influenzae 86-028NP 3430479 YP_248715.1 CDS NTHI1199 NC_007146.2 1143707 1144909 D Similar to: HI1038, YA38_HAEIN; ATPase 1143707..1144909 Haemophilus influenzae 86-028NP 3430480 YP_248716.1 CDS NTHI1201 NC_007146.2 1145099 1146448 R hypothetical protein complement(1145099..1146448) Haemophilus influenzae 86-028NP 3430481 YP_248717.1 CDS NTHI1203 NC_007146.2 1146916 1147416 R Similar to: HI1043, YA43_HAEIN; ferredoxin complement(1146916..1147416) Haemophilus influenzae 86-028NP 3430482 YP_248718.1 CDS NTHI1204 NC_007146.2 1147416 1148027 R binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD complement(1147416..1148027) Haemophilus influenzae 86-028NP 3430483 YP_248719.1 CDS dmsC NC_007146.2 1148139 1148978 R DMSO reductase anchor subunit; Similar to: HI1045, DMSC_HAEIN; anaerobic dimethyl sulfoxide reductase chain C complement(1148139..1148978) Haemophilus influenzae 86-028NP 3430484 YP_248720.1 CDS dmsB NC_007146.2 1148980 1149597 R DMSO reductase iron-sulfur subunit; Similar to: HI1046, DMSB_HAEIN; anaerobic dimethyl sulfoxide reductase chain B complement(1148980..1149597) Haemophilus influenzae 86-028NP 3430485 YP_248721.1 CDS dmsA NC_007146.2 1149608 1152028 R DMSO reductase; Similar to: HI1047, DMSA_HAEIN; anaerobic dimethyl sulfoxide reductase chain A complement(1149608..1152028) Haemophilus influenzae 86-028NP 3430486 YP_248722.1 CDS NTHI1208 NC_007146.2 1152281 1153390 D Similar to: HI1048, YA48_HAEIN; hypothetical protein 1152281..1153390 Haemophilus influenzae 86-028NP 3430487 YP_248723.1 CDS NTHI1209 NC_007146.2 1153434 1153727 D Similar to: HI1049, YA49_HAEIN; mercuric transporter MerT 1153434..1153727 Haemophilus influenzae 86-028NP 3430488 YP_248724.1 CDS NTHI1211 NC_007146.2 1153736 1154014 D Similar to: HI1050, YA50_HAEIN; copper chaperone MerP-like protein 1153736..1154014 Haemophilus influenzae 86-028NP 3430489 YP_248725.1 CDS NTHI1212 NC_007146.2 1154139 1155983 R Similar to: HI1051, YA51_HAEIN; ABC transporter ATP-binding protein complement(1154139..1155983) Haemophilus influenzae 86-028NP 3430490 YP_248726.1 CDS NTHI1213 NC_007146.2 1156062 1156958 R Similar to: HI1052, YA52_HAEIN; transcriptional regulator complement(1156062..1156958) Haemophilus influenzae 86-028NP 3430491 YP_248727.1 CDS NTHI1214 NC_007146.2 1157070 1157411 D Similar to: HI1053, YA53_HAEIN; hypothetical protein 1157070..1157411 Haemophilus influenzae 86-028NP 3430492 YP_248728.1 CDS NTHI1215 NC_007146.2 1157522 1158118 R Similar to: HI1054, YA54_HAEIN; hypothetical protein complement(1157522..1158118) Haemophilus influenzae 86-028NP 3430493 YP_248729.1 CDS res NC_007146.2 1158124 1160289 R Similar to: HI1055, T3RH_HAEIN; type III restriction-modification system HindVIP enzyme res complement(1158124..1160289) Haemophilus influenzae 86-028NP 3430494 YP_248730.1 CDS rnhB NC_007146.2 1162596 1163189 R RNase HII; RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(1162596..1163189) Haemophilus influenzae 86-028NP 3430496 YP_248731.1 CDS lpxB NC_007146.2 1163182 1164354 R catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase complement(1163182..1164354) Haemophilus influenzae 86-028NP 3430497 YP_248732.1 CDS lpxA NC_007146.2 1164421 1165209 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(1164421..1165209) Haemophilus influenzae 86-028NP 3430498 YP_248733.1 CDS fabZ NC_007146.2 1165223 1165669 R (3R)-hydroxymyristoyl ACP dehydrase; in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(1165223..1165669) Haemophilus influenzae 86-028NP 3430499 YP_248734.1 CDS NTHI1224 NC_007146.2 1165745 1167352 R Similar to: HI1064, YA64_HAEIN; PE--lipooligosaccharide phosphorylethanolamine transferase complement(1165745..1167352) Haemophilus influenzae 86-028NP 3430500 YP_248735.1 CDS pyrH NC_007146.2 1167445 1168158 D UK; uridine monophosphate kinase; UMP kinase; Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1167445..1168158 Haemophilus influenzae 86-028NP 3430501 YP_248736.1 CDS nrfD NC_007146.2 1168397 1169362 R Similar to: HI1066, NRFD_HAEIN; NrfD, formate-dependent nitrite reductase, membrane component complement(1168397..1169362) Haemophilus influenzae 86-028NP 3430502 YP_248737.1 CDS nrfC NC_007146.2 1169359 1170036 R Similar to: HI1067, NRFC_HAEIN; NrfC, Fe-S-cluster-containing hydrogenase component 1 complement(1169359..1170036) Haemophilus influenzae 86-028NP 3430503 YP_248738.1 CDS nrfB NC_007146.2 1170033 1170716 R part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit complement(1170033..1170716) Haemophilus influenzae 86-028NP 3430504 YP_248739.1 CDS nrfA NC_007146.2 1170760 1172376 R ammonia-forming cytochrome c nitrite reductase; cytochrome c nitrite reductase; catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 complement(1170760..1172376) Haemophilus influenzae 86-028NP 3430505 YP_248740.2 CDS hrpA NC_007146.2 1172538 1176374 R involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA complement(1172538..1176374) Haemophilus influenzae 86-028NP 3430506 YP_248741.1 CDS NTHI1232 NC_007146.2 1176443 1176817 R Similar to: HI1073, YGDD_HAEIN; small membrane protein complement(1176443..1176817) Haemophilus influenzae 86-028NP 3430507 YP_248742.1 CDS NTHI1233 NC_007146.2 1176818 1177270 R Similar to: HI1074, YEAL_HAEIN; hypothetical protein complement(1176818..1177270) Haemophilus influenzae 86-028NP 3430508 YP_248743.1 CDS cyoB NC_007146.2 1177536 1178672 R Similar to: HI1075, CYOB_HAEIN; cytochrome oxidase subunit II complement(1177536..1178672) Haemophilus influenzae 86-028NP 3430509 YP_248744.1 CDS cyoA NC_007146.2 1178687 1180252 R Similar to: HI1076, CYOA_HAEIN; cytochrome oxidase subunit I complement(1178687..1180252) Haemophilus influenzae 86-028NP 3430510 YP_248745.1 CDS pyrG NC_007146.2 1180905 1182542 D CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1180905..1182542 Haemophilus influenzae 86-028NP 3430511 YP_248746.1 CDS pnuC NC_007146.2 1182687 1183367 R NR; Similar to: HI1077.1, YA7B_HAEIN; nicotinamide riboside transporter complement(1182687..1183367) Haemophilus influenzae 86-028NP 3430512 YP_248747.1 CDS NTHI1241 NC_007146.2 1183549 1184322 R Similar to: HI1078, YA78_HAEIN; amino-acid ABC transporter ATP-binding protein complement(1183549..1184322) Haemophilus influenzae 86-028NP 3430513 YP_248748.1 CDS NTHI1242 NC_007146.2 1184326 1185003 R Similar to: HI1079, YA79_HAEIN; amino-acid ABC transporter permease protein complement(1184326..1185003) Haemophilus influenzae 86-028NP 3430514 YP_248749.1 CDS NTHI1243 NC_007146.2 1185026 1185799 R Similar to: HI1080, YA80_HAEIN; amino-acid ABC transporter binding protein complement(1185026..1185799) Haemophilus influenzae 86-028NP 3430515 YP_248750.1 CDS murA NC_007146.2 1186100 1187374 R enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT; adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(1186100..1187374) Haemophilus influenzae 86-028NP 3430516 YP_248751.1 CDS NTHI1245 NC_007146.2 1187385 1187642 R Similar to: HI1082, YRBA_HAEIN; BolA family transcriptional regulator complement(1187385..1187642) Haemophilus influenzae 86-028NP 3430517 YP_248752.1 CDS NTHI1246 NC_007146.2 1187663 1187980 R Similar to: HI1083, YA83_HAEIN; NTP binding protein, contains STAS domain complement(1187663..1187980) Haemophilus influenzae 86-028NP 3430518 YP_248753.1 CDS NTHI1247 NC_007146.2 1187991 1188635 R Similar to: HI1084, YRBC_HAEIN; ABC transporter complement(1187991..1188635) Haemophilus influenzae 86-028NP 3430519 YP_248754.1 CDS NTHI1248 NC_007146.2 1188668 1189168 R Similar to: HI1085, YRBD_HAEIN; ABC transporter periplasmic protein complement(1188668..1189168) Haemophilus influenzae 86-028NP 3430520 YP_248755.1 CDS NTHI1249 NC_007146.2 1189178 1189963 R Similar to: HI1086, YRBE_HAEIN; ABC transporter permease complement(1189178..1189963) Haemophilus influenzae 86-028NP 3430521 YP_248756.1 CDS NTHI1250 NC_007146.2 1189960 1190754 R Similar to: HI1087, YRBF_HAEIN; ABC transporter ATPase complement(1189960..1190754) Haemophilus influenzae 86-028NP 3430522 YP_248757.1 CDS sodA NC_007146.2 1191160 1191807 R Mn; Similar to: HI1088, SODM_HAEIN; superoxide dismutase complement(1191160..1191807) Haemophilus influenzae 86-028NP 3430523 YP_248758.1 CDS ccmA NC_007146.2 1192056 1192694 D cytochrome c-type biogenesis ATP-binding protein CcmA; ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 1192056..1192694 Haemophilus influenzae 86-028NP 3430524 YP_248759.1 CDS ccmB NC_007146.2 1192699 1193364 D cytochrome c-type biogenesis protein CcmB; Similar to: HI1090, CCMB_HAEIN; heme exporter protein B 1192699..1193364 Haemophilus influenzae 86-028NP 3430525 YP_248760.1 CDS ccmC NC_007146.2 1193425 1194165 D cytochrome c-type biogenesis protein CcmC; Similar to: HI1091, CCMC_HAEIN; heme exporter protein C 1193425..1194165 Haemophilus influenzae 86-028NP 3430526 YP_248761.1 CDS ccmD NC_007146.2 1194208 1194411 D cytochrome c-type biogenesis protein CcmD; Similar to: HI1092, CCMD_HAEIN; heme exporter protein D 1194208..1194411 Haemophilus influenzae 86-028NP 3430527 YP_248762.1 CDS ccmE NC_007146.2 1194408 1194929 D CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 1194408..1194929 Haemophilus influenzae 86-028NP 3430528 YP_248763.1 CDS ccmF NC_007146.2 1194926 1196872 D Similar to: HI1094, CCMF_HAEIN; cytochrome c-type biogenesis protein CcmF 1194926..1196872 Haemophilus influenzae 86-028NP 3430529 YP_248764.1 CDS dsbE NC_007146.2 1197015 1197560 D cytochrome c biogenesis protein CcmG; Similar to: HI1095, DSBE_HAEIN; thiol-disulfide interchange protein 1197015..1197560 Haemophilus influenzae 86-028NP 3430530 YP_248765.1 CDS NTHI1262 NC_007146.2 1199060 1199551 D hypothetical protein 1199060..1199551 Haemophilus influenzae 86-028NP 3430532 YP_248766.1 CDS NTHI1263 NC_007146.2 1199553 1199861 D Similar to: HI1099, YA99_HAEIN; hypothetical protein 1199553..1199861 Haemophilus influenzae 86-028NP 3430533 YP_248767.2 CDS ligA NC_007146.2 1199866 1201878 R polydeoxyribonucleotide synthase; this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(1199866..1201878) Haemophilus influenzae 86-028NP 3430534 YP_248768.1 CDS zipA NC_007146.2 1201990 1202976 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(1201990..1202976) Haemophilus influenzae 86-028NP 3430535 YP_248769.1 CDS cysZ NC_007146.2 1203129 1203947 D role in sulfur assimilation; sulfate transport protein CysZ 1203129..1203947 Haemophilus influenzae 86-028NP 3430536 YP_248770.1 CDS cysK NC_007146.2 1204046 1204996 D O-acetylserine sulfhydrylase; O-acetylserine (Thiol)-lyase; CSase; Similar to: HI1103, CYSK_HAEIN; cysteine synthase 1204046..1204996 Haemophilus influenzae 86-028NP 3430537 YP_248771.1 CDS rfaF NC_007146.2 1206577 1207617 R Similar to: HI1105, RFAF_HAEIN; ADP-heptose--lipooligosaccharide heptosyltransferase II complement(1206577..1207617) Haemophilus influenzae 86-028NP 3430539 YP_248772.1 CDS xylR NC_007146.2 1207693 1208856 R Similar to: HI1106, XYLR_HAEIN; xylose operon regulatory protein complement(1207693..1208856) Haemophilus influenzae 86-028NP 3430540 YP_248773.1 CDS NTHI1274 NC_007146.2 1208968 1210374 R Similar to: HI1107, YB07_HAEIN; Na(+)/H(+) antiporter complement(1208968..1210374) Haemophilus influenzae 86-028NP 3430541 YP_248774.1 CDS aspC2 NC_007146.2 1210376 1211548 R Similar to: PATB_BACSU; aspartate aminotransferase complement(1210376..1211548) Haemophilus influenzae 86-028NP 3430542 YP_248775.1 CDS xylA NC_007146.2 1211761 1213080 D catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 1211761..1213080 Haemophilus influenzae 86-028NP 3430543 YP_248776.1 CDS xylB NC_007146.2 1213083 1214618 D xylulokinase; Similar to: HI1113, XYLB_HAEIN; xylulose kinase 1213083..1214618 Haemophilus influenzae 86-028NP 3430544 YP_248777.1 CDS rfaD NC_007146.2 1214669 1215595 R ADP-glyceromanno-heptose 6-epimerase; catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase complement(1214669..1215595) Haemophilus influenzae 86-028NP 3430545 YP_248778.1 CDS NTHI1279 NC_007146.2 1215648 1216151 R Similar to: HI1115, THIX_HAEIN; thioredoxin-like protein complement(1215648..1216151) Haemophilus influenzae 86-028NP 3430546 YP_248779.1 CDS deoC NC_007146.2 1216262 1216933 D phosphodeoxyriboaldolase; deoxyriboaldolase; DERA; catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 1216262..1216933 Haemophilus influenzae 86-028NP 3430547 YP_248780.1 CDS comM NC_007146.2 1216967 1218496 R Similar to: HI1117, COMM_HAEIN; competence protein ComM complement(1216967..1218496) Haemophilus influenzae 86-028NP 3430548 YP_248781.1 CDS engB NC_007146.2 1218611 1219228 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(1218611..1219228) Haemophilus influenzae 86-028NP 3430549 YP_248782.1 CDS NTHI1285 NC_007146.2 1219321 1220199 D Similar to: HI1119, YB19_HAEIN; D-xylose transport permease protein 1219321..1220199 Haemophilus influenzae 86-028NP 3430550 YP_248783.1 CDS oppF NC_007146.2 1220239 1221237 R Similar to: HI1120, OPPF_HAEIN; oligopeptide transport ATP-binding protein complement(1220239..1221237) Haemophilus influenzae 86-028NP 3430551 YP_248784.1 CDS oppD NC_007146.2 1221234 1222205 R Similar to: HI1121, OPPD_HAEIN; oligopeptide transporter ATP-binding protein complement(1221234..1222205) Haemophilus influenzae 86-028NP 3430552 YP_248785.1 CDS oppC NC_007146.2 1222215 1223150 R Similar to: HI1122, OPPC_HAEIN; oligopeptide transport system permease protein complement(1222215..1223150) Haemophilus influenzae 86-028NP 3430553 YP_248786.1 CDS oppB NC_007146.2 1223160 1224080 R Similar to: HI1123, OPPB_HAEIN; oligopeptide transporter permease complement(1223160..1224080) Haemophilus influenzae 86-028NP 3430554 YP_248787.1 CDS oppA NC_007146.2 1224161 1225786 R Similar to: HI1124, OPPA_HAEIN; periplasmic oligopeptide-binding protein complement(1224161..1225786) Haemophilus influenzae 86-028NP 3430555 YP_248788.1 CDS talB NC_007146.2 1226081 1227034 D Maintains the balance of metabolites in the pentose-phosphate pathway; transaldolase B 1226081..1227034 Haemophilus influenzae 86-028NP 3430556 YP_248789.1 CDS NTHI1295 NC_007146.2 1228095 1229696 D Similar to: HI1126.1, YB2X_HAEIN; carbon starvation protein, membrane protein 1228095..1229696 Haemophilus influenzae 86-028NP 3430557 YP_248790.1 CDS mraZ NC_007146.2 1229898 1230353 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 1229898..1230353 Haemophilus influenzae 86-028NP 3430558 YP_248791.1 CDS mraW NC_007146.2 1230384 1231349 D Similar to: HI1130, MRAW_HAEIN; S-adenosyl-methyltransferase MraW 1230384..1231349 Haemophilus influenzae 86-028NP 3430559 YP_248792.1 CDS ftsL NC_007146.2 1231352 1231675 D Similar to: HI1131, FTSL_HAEIN; cell division protein FtsL 1231352..1231675 Haemophilus influenzae 86-028NP 3430560 YP_248793.1 CDS ftsI NC_007146.2 1231688 1233520 D peptidoglycan glycosyltransferase 3; penicillin-binding protein 3; PBP-3; Similar to: HI1132, FTSI_HAEIN; peptidoglycan synthetase FtsI 1231688..1233520 Haemophilus influenzae 86-028NP 3430561 YP_248794.1 CDS murE NC_007146.2 1233530 1234996 D UDP-N-acetylmuramyl-tripeptide synthetase; Meso-diaminopimelate-adding enzyme; UDP-MurNAc-tripeptide synthetase; involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1233530..1234996 Haemophilus influenzae 86-028NP 3430562 YP_248795.1 CDS murF NC_007146.2 1235010 1236383 D UDP-MurNAc-pentapeptide synthetase; D-alanyl-D-alanine-adding enzyme; Similar to: HI1134, MURF_HAEIN; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 1235010..1236383 Haemophilus influenzae 86-028NP 3430563 YP_248796.1 CDS mraY NC_007146.2 1236377 1237459 D UDP-MurNAc-pentapeptide phosphotransferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1236377..1237459 Haemophilus influenzae 86-028NP 3430564 YP_248797.1 CDS murD NC_007146.2 1237571 1238884 D UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; D-glutamic acid adding enzyme; UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 1237571..1238884 Haemophilus influenzae 86-028NP 3430565 YP_248798.1 CDS ftsW NC_007146.2 1238907 1240091 D Similar to: HI1137, FTSW_HAEIN; cell division protein FtsW 1238907..1240091 Haemophilus influenzae 86-028NP 3430566 YP_248799.1 CDS murG NC_007146.2 1240103 1241158 D pentapeptide; undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1240103..1241158 Haemophilus influenzae 86-028NP 3430567 YP_248800.1 CDS murC NC_007146.2 1241296 1242723 D UDP-N-acetylmuramoyl-L-alanine synthetase; Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1241296..1242723 Haemophilus influenzae 86-028NP 3430568 YP_248801.1 CDS ddl NC_007146.2 1242792 1243712 D D-alanylalanine synthetase; D-Ala-D-Ala ligase; D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 1242792..1243712 Haemophilus influenzae 86-028NP 3430569 YP_248802.1 CDS ftsQ NC_007146.2 1243712 1244476 D Similar to: HI1141, FTSQ_HAEIN; cell division protein FtsQ 1243712..1244476 Haemophilus influenzae 86-028NP 3430570 YP_248803.1 CDS ftsA NC_007146.2 1244495 1245772 D Similar to: HI1142, FTSA_HAEIN; cell division protein FtsA 1244495..1245772 Haemophilus influenzae 86-028NP 3430571 YP_248804.1 CDS ftsZ NC_007146.2 1245856 1247121 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1245856..1247121 Haemophilus influenzae 86-028NP 3430572 YP_248805.1 CDS lpxC NC_007146.2 1247160 1248077 D UDP-3-O-acyl-GlcNAc deacetylase; zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 1247160..1248077 Haemophilus influenzae 86-028NP 3430573 YP_248806.1 CDS pheA NC_007146.2 1248204 1249361 D CM; PDT; Similar to: HI1145, PHEA_HAEIN; P-protein 1248204..1249361 Haemophilus influenzae 86-028NP 3430574 YP_248807.1 CDS NTHI1314 NC_007146.2 1249406 1250263 R Similar to: HI1146, YB46_HAEIN; hypothetical protein complement(1249406..1250263) Haemophilus influenzae 86-028NP 3430575 YP_248808.1 CDS ptsN NC_007146.2 1250281 1250775 R Similar to: HI1147, PTSN_HAEIN; nitrogen regulatory IIA protein complement(1250281..1250775) Haemophilus influenzae 86-028NP 3430576 YP_248809.1 CDS NTHI1316 NC_007146.2 1250778 1251503 R Similar to: HI1148, YHBG_HAEIN; ABC transporter ATP-binding protein complement(1250778..1251503) Haemophilus influenzae 86-028NP 3430577 YP_248810.1 CDS NTHI1317 NC_007146.2 1251507 1252025 R Similar to: HI1149, YHBN_HAEIN; hypothetical protein complement(1251507..1252025) Haemophilus influenzae 86-028NP 3430578 YP_248811.1 CDS NTHI1318 NC_007146.2 1252006 1252614 R Similar to: HI1150, YRBK_HAEIN; hypothetical protein complement(1252006..1252614) Haemophilus influenzae 86-028NP 3430579 YP_248812.1 CDS NTHI1319 NC_007146.2 1252664 1253200 R Similar to: HI1151, YJGA_HAEIN; hypothetical protein complement(1252664..1253200) Haemophilus influenzae 86-028NP 3430580 YP_248813.1 CDS pmbA NC_007146.2 1253289 1254644 D Similar to: HI1152, PMBA_HAEIN; hypothetical protein 1253289..1254644 Haemophilus influenzae 86-028NP 3430581 YP_248814.1 CDS hpt NC_007146.2 1255019 1255558 D HPRT; Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 1255019..1255558 Haemophilus influenzae 86-028NP 3430582 YP_248815.1 CDS NTHI1323 NC_007146.2 1255864 1257186 D Similar to: HI1154, YDJN_HAEIN; Na+/dicarboxylate symporter 1255864..1257186 Haemophilus influenzae 86-028NP 3430583 YP_248816.1 CDS nrdG NC_007146.2 1257286 1257753 R Class III anaerobic ribonucleotide reductase small component; activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(1257286..1257753) Haemophilus influenzae 86-028NP 3430584 YP_248817.1 CDS cydC NC_007146.2 1258001 1259731 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component complement(1258001..1259731) Haemophilus influenzae 86-028NP 3430585 YP_248818.1 CDS cydD NC_007146.2 1259731 1261491 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component complement(1259731..1261491) Haemophilus influenzae 86-028NP 3430586 YP_248819.1 CDS trxB NC_007146.2 1261563 1262519 R TRXR; Similar to: HI1158, TRXB_HAEIN; thioredoxin reductase complement(1261563..1262519) Haemophilus influenzae 86-028NP 3430587 YP_248820.1 CDS NTHI1328 NC_007146.2 1262593 1263450 R Similar to: HI1159, YBBN_HAEIN; thioredoxin complement(1262593..1263450) Haemophilus influenzae 86-028NP 3430588 YP_248821.1 CDS hemH NC_007146.2 1263529 1264500 R protoheme ferro-lyase; heme synthetase; protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(1263529..1264500) Haemophilus influenzae 86-028NP 3430589 YP_248822.1 CDS NTHI1330 NC_007146.2 1264497 1264913 R Similar to: HI1161, YB61_HAEIN; hypothetical protein complement(1264497..1264913) Haemophilus influenzae 86-028NP 3430590 YP_248823.1 CDS NTHI1331 NC_007146.2 1264927 1268010 R Similar to: HI1163, YDIJ_HAEIN; hypothetical protein complement(1264927..1268010) Haemophilus influenzae 86-028NP 3430591 YP_248824.1 CDS ompP5 NC_007146.2 1268385 1269464 D OMP P5-homologous adhesin; Similar to: HI1164, OM53_HAEIN; outer membrane protein P5 1268385..1269464 Haemophilus influenzae 86-028NP 3430592 YP_248825.1 CDS NTHI1333 NC_007146.2 1269576 1269938 D Similar to: HI1165, YDHD_HAEIN; glutaredoxin-like protein 1269576..1269938 Haemophilus influenzae 86-028NP 3430593 YP_248826.1 CDS NTHI1334 NC_007146.2 1270015 1271115 R imidazole acetol-phosphate transaminase 2; catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase complement(1270015..1271115) Haemophilus influenzae 86-028NP 3430594 YP_248827.1 CDS serC NC_007146.2 1271203 1272291 R PSAT; catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase complement(1271203..1272291) Haemophilus influenzae 86-028NP 3430595 YP_248828.1 CDS NTHI1336 NC_007146.2 1272482 1272826 D Similar to: HI1168, YB68_HAEIN; hypothetical protein 1272482..1272826 Haemophilus influenzae 86-028NP 3430596 YP_248829.1 CDS NTHI1337 NC_007146.2 1272866 1273432 R Similar to: HI1169, YB69_HAEIN; hypothetical protein complement(1272866..1273432) Haemophilus influenzae 86-028NP 3430597 YP_248830.1 CDS NTHI1338 NC_007146.2 1273432 1274418 R catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; para-aminobenzoate synthase component I complement(1273432..1274418) Haemophilus influenzae 86-028NP 3430598 YP_248831.1 CDS trpG2 NC_007146.2 1274460 1275041 D glutamine amido-transferase; catalyzes the formation of anthranilate from chorismate and glutamine; functions in tryptophan biosynthesis; anthranilate synthase component II 1274460..1275041 Haemophilus influenzae 86-028NP 3430599 YP_248832.1 CDS metK NC_007146.2 1275126 1276280 D methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1275126..1276280 Haemophilus influenzae 86-028NP 3430600 YP_248833.1 CDS sprT NC_007146.2 1276575 1277090 D Similar to: HI1173, SPRT_HAEIN; hypothetical protein 1276575..1277090 Haemophilus influenzae 86-028NP 3430601 YP_248834.1 CDS opa NC_007146.2 1277141 1277653 D Similar to: HI1174, OPA_HAEIN; opacity protein 1277141..1277653 Haemophilus influenzae 86-028NP 3430602 YP_248835.1 CDS NTHI1344 NC_007146.2 1277689 1277994 R Similar to: HI1176; hypothetical protein complement(1277689..1277994) Haemophilus influenzae 86-028NP 3430603 YP_248836.1 CDS artM NC_007146.2 1278201 1278884 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(1278201..1278884) Haemophilus influenzae 86-028NP 3430604 YP_248837.1 CDS artQ NC_007146.2 1278884 1279549 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(1278884..1279549) Haemophilus influenzae 86-028NP 3430605 YP_248838.1 CDS artI NC_007146.2 1279553 1280272 R Similar to: HI1179, ARTI_HAEIN; arginine-binding periplasmic protein complement(1279553..1280272) Haemophilus influenzae 86-028NP 3430606 YP_248839.1 CDS artP NC_007146.2 1280290 1281021 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(1280290..1281021) Haemophilus influenzae 86-028NP 3430607 YP_248840.1 CDS gmhA NC_007146.2 1281147 1281731 R catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase complement(1281147..1281731) Haemophilus influenzae 86-028NP 3430608 YP_248841.1 CDS ligA NC_007146.2 1281831 1282745 D polydeoxyribonucleotide synthase; catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA; DNA ligase 1281831..1282745 Haemophilus influenzae 86-028NP 3430609 YP_248842.1 CDS dppF NC_007146.2 1282774 1283757 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit complement(1282774..1283757) Haemophilus influenzae 86-028NP 3430610 YP_248843.1 CDS dppD NC_007146.2 1283760 1284752 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit complement(1283760..1284752) Haemophilus influenzae 86-028NP 3430611 YP_248844.1 CDS dppC NC_007146.2 1284762 1285649 R Similar to: HI1186, DPPC_HAEIN; dipeptide transport system permease protein complement(1284762..1285649) Haemophilus influenzae 86-028NP 3430612 YP_248845.1 CDS dppB NC_007146.2 1285664 1286665 R Similar to: HI1187, DPPB_HAEIN; dipeptide transport system permease protein complement(1285664..1286665) Haemophilus influenzae 86-028NP 3430613 YP_248846.1 CDS uvrD NC_007146.2 1286755 1288938 R unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II complement(1286755..1288938) Haemophilus influenzae 86-028NP 3430614 YP_248847.1 CDS NTHI1360 NC_007146.2 1289545 1290180 R Similar to: HI1189, YGCF_HAEIN; organic radical activating protein complement(1289545..1290180) Haemophilus influenzae 86-028NP 3430615 YP_248848.1 CDS NTHI1361 NC_007146.2 1290181 1290606 R Similar to: HI1190, YB90_HAEIN; 6-pyruvoyl tetrahydrobiopterin synthase complement(1290181..1290606) Haemophilus influenzae 86-028NP 3430616 YP_248849.1 CDS NTHI1362 NC_007146.2 1290599 1291282 R Similar to: HI1191, YBAX_HAEIN; PP-loop superfamily ATPase complement(1290599..1291282) Haemophilus influenzae 86-028NP 3430617 YP_248850.1 CDS NTHI1363 NC_007146.2 1291438 1291581 D Similar to: HI1192, YB92_HAEIN; hypothetical protein 1291438..1291581 Haemophilus influenzae 86-028NP 3430618 YP_248851.1 CDS ilvE NC_007146.2 1291632 1292663 R BCAT; catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(1291632..1292663) Haemophilus influenzae 86-028NP 3430619 YP_248852.1 CDS gcvA NC_007146.2 1293138 1294031 D Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 1293138..1294031 Haemophilus influenzae 86-028NP 3430620 YP_248853.1 CDS NTHI1366 NC_007146.2 1294024 1295115 D Similar to: HI1195, YGDE_HAEIN; RNA 2'-O-ribose methyltransferase 1294024..1295115 Haemophilus influenzae 86-028NP 3430621 YP_248854.1 CDS sucC NC_007146.2 1295151 1296320 D SCS-beta; catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1295151..1296320 Haemophilus influenzae 86-028NP 3430622 YP_248855.1 CDS sucD NC_007146.2 1296320 1297201 D SCS-alpha; Similar to: HI1197, SUCD_HAEIN; succinyl-CoA synthetase alpha chain 1296320..1297201 Haemophilus influenzae 86-028NP 3430623 YP_248856.1 CDS NTHI1369 NC_007146.2 1297322 1297945 D Similar to: HI1198, YCIO_HAEIN; hypothetical protein 1297322..1297945 Haemophilus influenzae 86-028NP 3430624 YP_248857.1 CDS rluB NC_007146.2 1297993 1299066 D pseudouridylate synthase; Uracil hydrolyase; Similar to: HI1199, RLUB_HAEIN; ribosomal large subunit pseudouridine synthase B 1297993..1299066 Haemophilus influenzae 86-028NP 3430625 YP_248858.1 CDS cysB NC_007146.2 1299077 1300048 D Cys regulon transcriptional activator; LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1299077..1300048 Haemophilus influenzae 86-028NP 3430626 YP_248859.1 CDS NTHI1372 NC_007146.2 1300107 1301051 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(1300107..1301051) Haemophilus influenzae 86-028NP 3430627 YP_248860.1 CDS NTHI1373 NC_007146.2 1301182 1301685 D Similar to: HI1202, YC02_HAEIN; hypothetical protein 1301182..1301685 Haemophilus influenzae 86-028NP 3430628 YP_248861.1 CDS pta NC_007146.2 1301763 1303898 R phosphotransacetylase; catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase complement(1301763..1303898) Haemophilus influenzae 86-028NP 3430629 YP_248862.1 CDS ackA NC_007146.2 1303966 1305171 R acetokinase; AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(1303966..1305171) Haemophilus influenzae 86-028NP 3430630 YP_248863.1 CDS NTHI1376 NC_007146.2 1305388 1305831 D Similar to: HI1205, YC05_HAEIN; hypothetical protein 1305388..1305831 Haemophilus influenzae 86-028NP 3430631 YP_248864.1 CDS cvpA NC_007146.2 1305918 1306409 D Similar to: HI1206, CVPA_HAEIN; colicin V production protein 1305918..1306409 Haemophilus influenzae 86-028NP 3430632 YP_248865.1 CDS purF NC_007146.2 1306420 1307937 D glutamine phosphoribosylpyrophosphate amidotransferase; ATASE; GPATase; Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1306420..1307937 Haemophilus influenzae 86-028NP 3430633 YP_248866.1 CDS sulA NC_007146.2 1308002 1308892 R Similar to: HI1208, YFCH_HAEIN; cell division inhibitor SulA complement(1308002..1308892) Haemophilus influenzae 86-028NP 3430634 YP_248867.1 CDS argR NC_007146.2 1308892 1309347 R regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR complement(1308892..1309347) Haemophilus influenzae 86-028NP 3430635 YP_248868.1 CDS mdh NC_007146.2 1309554 1310489 D oxidizes malate to oxaloacetate; malate dehydrogenase 1309554..1310489 Haemophilus influenzae 86-028NP 3430636 YP_248869.1 CDS lysS NC_007146.2 1310576 1312084 R Lysine--tRNA ligase; LysRS; class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(1310576..1312084) Haemophilus influenzae 86-028NP 3430637 YP_248870.1 CDS prfB NC_007146.2 1312196 1313047 R RF-2; Similar to: HI1561, RF2_HAEIN; peptide chain release factor 2 complement(1312196..1313047) Haemophilus influenzae 86-028NP 3430638 YP_248871.1 CDS dsbC NC_007146.2 1313427 1314116 D Similar to: HI1213, DSBC_HAEIN; thiol-disulfide interchange protein 1313427..1314116 Haemophilus influenzae 86-028NP 3430639 YP_248872.1 CDS recJ NC_007146.2 1314404 1316131 D Similar to: HI1214, RECJ_HAEIN; single-stranded-DNA-specific exonuclease RecJ 1314404..1316131 Haemophilus influenzae 86-028NP 3430640 YP_248873.1 CDS NTHI1387 NC_007146.2 1316124 1316831 D Similar to: HI1215, YC15_HAEIN; hypothetical protein 1316124..1316831 Haemophilus influenzae 86-028NP 3430641 YP_248874.1 CDS mtnA NC_007146.2 1316828 1317520 D enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1316828..1317520 Haemophilus influenzae 86-028NP 3430642 YP_248875.1 CDS hup NC_007146.2 1317594 1320341 R Similar to: HI1217, YC17_HAEIN; heme utilization protein complement(1317594..1320341) Haemophilus influenzae 86-028NP 3430643 YP_248876.1 CDS NTHI1391 NC_007146.2 1320641 1322239 R Similar to: HI1218, YC18_HAEIN; L-lactate permease complement(1320641..1322239) Haemophilus influenzae 86-028NP 3430644 YP_248877.1 CDS fbp NC_007146.2 1322643 1323647 R D-fructose-1,6-bisphosphate 1-phosphohydrolase; FBPase; catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(1322643..1323647) Haemophilus influenzae 86-028NP 3430646 YP_248878.1 CDS truA NC_007146.2 1323882 1324691 D pseudouridylate synthase I; pseudouridine synthase I; Uracil hydrolyase; mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1323882..1324691 Haemophilus influenzae 86-028NP 3430647 YP_248879.1 CDS sapZ NC_007146.2 1324784 1325800 R Similar to: HI1643, YEIH_HAEIN; hypothetical protein complement(1324784..1325800) Haemophilus influenzae 86-028NP 3430648 YP_248880.1 CDS sapF NC_007146.2 1325812 1326621 R Similar to: HI1642, SAPF_HAEIN; anti peptide resistance ABC transporter ATPase complement(1325812..1326621) Haemophilus influenzae 86-028NP 3430649 YP_248881.1 CDS sapD NC_007146.2 1326621 1327670 R Similar to: HI1641, SAPD_HAEIN; peptide ABC transporter ATP-binding protein complement(1326621..1327670) Haemophilus influenzae 86-028NP 3430650 YP_248882.1 CDS sapC NC_007146.2 1327674 1328561 R Similar to: HI1640, SAPC_HAEIN; ABC transporter permease complement(1327674..1328561) Haemophilus influenzae 86-028NP 3430651 YP_248883.1 CDS sapB NC_007146.2 1328551 1329516 R Similar to: HI1639, SAPB_HAEIN; ABC transporter permease complement(1328551..1329516) Haemophilus influenzae 86-028NP 3430652 YP_248884.1 CDS sapA NC_007146.2 1329516 1331210 R Similar to: HI1638, SAPA_HAEIN; anti peptide resistance ABC transporter periplasmic protein complement(1329516..1331210) Haemophilus influenzae 86-028NP 3430653 YP_248885.1 CDS NTHI1402 NC_007146.2 1331280 1332692 D Similar to: HI1637, YCJX_HAEIN; hypothetical protein 1331280..1332692 Haemophilus influenzae 86-028NP 3430654 YP_248886.1 CDS ppc NC_007146.2 1332729 1335368 R PEPCase; PEPC; catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(1332729..1335368) Haemophilus influenzae 86-028NP 3430655 YP_248887.1 CDS purR NC_007146.2 1335551 1336561 R Purine nucleotide synthesis repressor; binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR complement(1335551..1336561) Haemophilus influenzae 86-028NP 3430656 YP_248888.2 CDS dapD NC_007146.2 1336924 1337751 D tetrahydrodipicolinate N-succinyltransferase; THP succinyltransferase; tetrahydropicolinate succinylase; catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1336924..1337751 Haemophilus influenzae 86-028NP 3430657 YP_248889.1 CDS purA NC_007146.2 1337808 1339106 R IMP--aspartate ligase; AdSS; AMPSase; catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(1337808..1339106) Haemophilus influenzae 86-028NP 3430658 YP_248890.1 CDS NTHI1408 NC_007146.2 1339235 1339600 R Similar to: HI1632, YG32_HAEIN; aspartokinase complement(1339235..1339600) Haemophilus influenzae 86-028NP 3430659 YP_248891.1 CDS rplY NC_007146.2 1340448 1340735 R the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 complement(1340448..1340735) Haemophilus influenzae 86-028NP 3430664 YP_248892.1 CDS NTHI1412 NC_007146.2 1340903 1341559 D Similar to: HI1629, YG29_HAEIN; membrane-associated protein 1340903..1341559 Haemophilus influenzae 86-028NP 3430665 YP_248893.1 CDS NTHI1413 NC_007146.2 1341606 1342022 R Similar to: HI1628, YHCB_HAEIN; hypothetical protein complement(1341606..1342022) Haemophilus influenzae 86-028NP 3430666 YP_248894.1 CDS NTHI1414 NC_007146.2 1342053 1342403 R Similar to: HI1627, YG27_HAEIN; YjgF family translation initiation inhibitor complement(1342053..1342403) Haemophilus influenzae 86-028NP 3430667 YP_248895.1 CDS NTHI1415 NC_007146.2 1342515 1343231 D Similar to: HI1626, YG26_HAEIN; hypothetical protein 1342515..1343231 Haemophilus influenzae 86-028NP 3430668 YP_248896.1 CDS NTHI1416 NC_007146.2 1343232 1343774 D Similar to: HI1625, YG25_HAEIN; hypothetical protein 1343232..1343774 Haemophilus influenzae 86-028NP 3430669 YP_248897.1 CDS NTHI1417 NC_007146.2 1343789 1344247 R Similar to: HI1623, ZNTR_HAEIN; HTH-type transcriptional regulator complement(1343789..1344247) Haemophilus influenzae 86-028NP 3430670 YP_248898.1 CDS NTHI1418 NC_007146.2 1344286 1344969 D Similar to: HI1624, YG24_HAEIN; ABC-type Co2+ transport system, periplasmic component 1344286..1344969 Haemophilus influenzae 86-028NP 3430671 YP_248899.1 CDS NTHI1419 NC_007146.2 1344982 1345470 D Similar to: HI1622, YG22_HAEIN; hypothetical protein 1344982..1345470 Haemophilus influenzae 86-028NP 3430672 YP_248900.1 CDS cbiM NC_007146.2 1345470 1346090 D catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM 1345470..1346090 Haemophilus influenzae 86-028NP 3430673 YP_248901.1 CDS NTHI1421 NC_007146.2 1346090 1346722 D Similar to: HI1620, YG20_HAEIN; cobalt ABC transporter permease 1346090..1346722 Haemophilus influenzae 86-028NP 3430674 YP_248902.1 CDS cbiO NC_007146.2 1346724 1347350 D Similar to: HI1618, YG18_HAEIN; cobalt ABC transporter ATPase 1346724..1347350 Haemophilus influenzae 86-028NP 3430675 YP_248903.1 CDS aspC NC_007146.2 1347457 1348647 R transaminase A; ASPAT; catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(1347457..1348647) Haemophilus influenzae 86-028NP 3430676 YP_248904.1 CDS purK NC_007146.2 1348787 1349875 R AIR carboxylase; AIRC; With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(1348787..1349875) Haemophilus influenzae 86-028NP 3430677 YP_248905.1 CDS purE NC_007146.2 1349945 1350439 R AIR carboxylase; AIRC; Catalyzes a step in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase catalytic subunit complement(1349945..1350439) Haemophilus influenzae 86-028NP 3430678 YP_248906.1 CDS hicA NC_007146.2 1350610 1350858 D HicA 1350610..1350858 Haemophilus influenzae 86-028NP 3430679 YP_248907.1 CDS hicB NC_007146.2 1350855 1351199 D HicB 1350855..1351199 Haemophilus influenzae 86-028NP 3430680 YP_248908.1 CDS pepN NC_007146.2 1351243 1353852 D alpha-aminoacylpeptide hydrolase; Similar to: HI1614, AMPN_HAEIN; aminopeptidase 1351243..1353852 Haemophilus influenzae 86-028NP 3430681 YP_248909.1 CDS ribE NC_007146.2 1353924 1354538 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1353924..1354538) Haemophilus influenzae 86-028NP 3430682 YP_248910.1 CDS norM NC_007146.2 1354582 1355976 D Na(+)/drug antiporter; multidrug-efflux transporter; NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1354582..1355976 Haemophilus influenzae 86-028NP 3430683 YP_248911.1 CDS sfsA NC_007146.2 1355985 1356701 D Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 1355985..1356701 Haemophilus influenzae 86-028NP 3430684 YP_248912.1 CDS tyrS NC_007146.2 1356901 1358088 D tyrosine--tRNA ligase; TyrRS; catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1356901..1358088 Haemophilus influenzae 86-028NP 3430685 YP_248913.1 CDS prsA NC_007146.2 1358152 1359099 R RPPK; phosphoribosyl pyrophosphate synthetase; P-Rib-PP synthetase; PRPP synthetase; catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1358152..1359099) Haemophilus influenzae 86-028NP 3430686 YP_248914.1 CDS ipk NC_007146.2 1359101 1360054 R CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase; An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1359101..1360054) Haemophilus influenzae 86-028NP 3430687 YP_248915.1 CDS lolB NC_007146.2 1360054 1360683 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB complement(1360054..1360683) Haemophilus influenzae 86-028NP 3430688 YP_248916.1 CDS cca NC_007146.2 1360746 1361996 R tRNA adenylyltransferase; tRNA CCA-pyrophosphorylase; CCA-adding enzyme; catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase complement(1360746..1361996) Haemophilus influenzae 86-028NP 3430689 YP_248917.1 CDS NTHI1437 NC_007146.2 1362003 1362614 R Similar to: HI1605, YGIM_HAEIN; hypothetical protein complement(1362003..1362614) Haemophilus influenzae 86-028NP 3430690 YP_248918.1 CDS NTHI1438 NC_007146.2 1362680 1363942 R Similar to: HI1604, YG04_HAEIN; phosphate permease complement(1362680..1363942) Haemophilus influenzae 86-028NP 3430691 YP_248919.1 CDS NTHI1439 NC_007146.2 1363967 1364647 R Similar to: HI1603, YG03_HAEIN; phosphate transport regulator complement(1363967..1364647) Haemophilus influenzae 86-028NP 3430692 YP_248920.1 CDS NTHI1440 NC_007146.2 1364855 1365310 D Similar to: HI1602, YG02_HAEIN; hypothetical protein 1364855..1365310 Haemophilus influenzae 86-028NP 3430693 YP_248921.1 CDS NTHI1441 NC_007146.2 1365349 1365636 D Similar to: HI1601, YG01_HAEIN; hypothetical protein 1365349..1365636 Haemophilus influenzae 86-028NP 3430694 YP_248922.1 CDS NTHI1443 NC_007146.2 1365666 1366619 D Similar to: HI1600, YG00_HAEIN; hypothetical protein 1365666..1366619 Haemophilus influenzae 86-028NP 3430695 YP_248923.1 CDS NTHI1444 NC_007146.2 1366609 1367325 D Similar to: HI1599, YF99_HAEIN; hypothetical protein 1366609..1367325 Haemophilus influenzae 86-028NP 3430696 YP_248924.1 CDS NTHI1445 NC_007146.2 1368433 1368600 D hypothetical protein 1368433..1368600 Haemophilus influenzae 86-028NP 3430697 YP_248925.1 CDS NTHI1446 NC_007146.2 1368998 1369114 D hypothetical protein 1368998..1369114 Haemophilus influenzae 86-028NP 3430698 YP_248926.1 CDS NTHI1447 NC_007146.2 1369564 1369728 R hypothetical protein complement(1369564..1369728) Haemophilus influenzae 86-028NP 3430699 YP_248927.1 CDS hmw2C NC_007146.2 1369918 1371870 R HMW2C, glycosyltransferase involved in glycosylation of HMW1A and HMW2A complement(1369918..1371870) Haemophilus influenzae 86-028NP 3430700 YP_248928.1 CDS hmw2B NC_007146.2 1372262 1373899 R HMW2B, OMP-85-like protein required for HMW1A and HMW2A secretion complement(1372262..1373899) Haemophilus influenzae 86-028NP 3430701 YP_248929.1 CDS hmw2A NC_007146.2 1374050 1378678 R HMW2A, high molecular weight adhesin 2 complement(1374050..1378678) Haemophilus influenzae 86-028NP 3430702 YP_248930.1 CDS NTHI1451 NC_007146.2 1379103 1380149 D Similar to: HI1598, YGIF_HAEIN; hypothetical protein 1379103..1380149 Haemophilus influenzae 86-028NP 3430703 YP_248931.1 CDS radA NC_007146.2 1380382 1381758 D DNA repair protein sms homolog; Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 1380382..1381758 Haemophilus influenzae 86-028NP 3430704 YP_248932.2 CDS lrp NC_007146.2 1381838 1382317 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 1381838..1382317 Haemophilus influenzae 86-028NP 3430705 YP_248933.1 CDS ftsK NC_007146.2 1382319 1385075 D Similar to: HI1592, FTSK_HAEIN; DNA translocase FtsK 1382319..1385075 Haemophilus influenzae 86-028NP 3430706 YP_248934.1 CDS lolA NC_007146.2 1385093 1385710 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1385093..1385710 Haemophilus influenzae 86-028NP 3430707 YP_248935.1 CDS NTHI1458 NC_007146.2 1385771 1387111 D Similar to: HI1590, YCAJ_HAEIN; recombination factor protein RarA 1385771..1387111 Haemophilus influenzae 86-028NP 3430708 YP_248936.1 CDS NTHI1459 NC_007146.2 1387199 1388341 R hypothetical protein complement(1387199..1388341) Haemophilus influenzae 86-028NP 3430709 YP_248937.1 CDS NTHI1460 NC_007146.2 1388351 1389574 R cytosine-specific methyltransferase BepI-like; Similar to: MTB1_BREEP; modification methylase BepI-like complement(1388351..1389574) Haemophilus influenzae 86-028NP 3430710 YP_248938.1 CDS aroA NC_007146.2 1389829 1391127 R 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS; catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase complement(1389829..1391127) Haemophilus influenzae 86-028NP 3430711 YP_248939.1 CDS purU NC_007146.2 1391127 1391963 R Formyl-FH(4) hydrolase; produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1391127..1391963) Haemophilus influenzae 86-028NP 3430712 YP_248940.1 CDS hns NC_007146.2 1392033 1392437 R Similar to: HI1587, HNS_HAEIN; DNA-binding protein H-NS-like protein complement(1392033..1392437) Haemophilus influenzae 86-028NP 3430713 YP_248941.1 CDS NTHI1465 NC_007146.2 1392841 1394400 D Similar to: HI1586, YF86_HAEIN; Na+/H+ antiporter 1392841..1394400 Haemophilus influenzae 86-028NP 3430714 YP_248942.1 CDS NTHI1466 NC_007146.2 1394468 1394617 D hypothetical protein 1394468..1394617 Haemophilus influenzae 86-028NP 3430715 YP_248943.1 CDS ilvI NC_007146.2 1394667 1396388 D AHAS; acetohydroxy-acid synthase large subunit; ALS; acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 3 catalytic subunit 1394667..1396388 Haemophilus influenzae 86-028NP 3430716 YP_248944.1 CDS ilvH NC_007146.2 1396388 1396879 D AHAS; acetohydroxy-acid synthase small subunit; ALS; with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1396388..1396879 Haemophilus influenzae 86-028NP 3430717 YP_248945.1 CDS argS NC_007146.2 1397173 1398906 R arginine--tRNA ligase; ArgRS; catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(1397173..1398906) Haemophilus influenzae 86-028NP 3430718 YP_248946.1 CDS NTHI1471 NC_007146.2 1398986 1399555 D Similar to: HI1582, YECM_HAEIN; hypothetical protein 1398986..1399555 Haemophilus influenzae 86-028NP 3430719 YP_248947.1 CDS NTHI1472 NC_007146.2 1399634 1399855 D lipoprotein 1399634..1399855 Haemophilus influenzae 86-028NP 3430720 YP_248948.1 CDS pcp NC_007146.2 1399878 1400342 D 15 kDa lipoprotein; PAL cross-reacting lipoprotein; Similar to: HI1579, PCP_HAEIN; outer membrane lipoprotein PCP 1399878..1400342 Haemophilus influenzae 86-028NP 3430721 YP_248949.1 CDS lgtD NC_007146.2 1400526 1401497 R Similar to: HI1578, YF78_HAEIN; UDP-GlcNAc--lipooligosaccharide N-acetylglucosamine glycosyltransferase complement(1400526..1401497) Haemophilus influenzae 86-028NP 3430722 YP_248950.2 CDS pgi NC_007146.2 1402135 1403784 R GPI; phosphoglucose isomerase; PGI; phosphohexose isomerase; PHI; functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(1402135..1403784) Haemophilus influenzae 86-028NP 3430724 YP_248951.1 CDS alr NC_007146.2 1403881 1404963 R converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase complement(1403881..1404963) Haemophilus influenzae 86-028NP 3430725 YP_248952.1 CDS dnaB NC_007146.2 1404973 1406487 R unwinds double stranded DNA; replicative DNA helicase complement(1404973..1406487) Haemophilus influenzae 86-028NP 3430726 YP_248953.1 CDS pykA NC_007146.2 1406521 1407957 R PK; catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(1406521..1407957) Haemophilus influenzae 86-028NP 3430727 YP_248954.1 CDS NTHI1480 NC_007146.2 1408494 1409753 D Similar to: INTA_ECOLI; prophage CP4-57-like integrase 1408494..1409753 Haemophilus influenzae 86-028NP 3430729 YP_248955.1 CDS NTHI1482 NC_007146.2 1410367 1410636 R hypothetical protein complement(1410367..1410636) Haemophilus influenzae 86-028NP 3430730 YP_248956.1 CDS NTHI1483 NC_007146.2 1410741 1410911 R hypothetical protein complement(1410741..1410911) Haemophilus influenzae 86-028NP 3430731 YP_248957.1 CDS NTHI1484 NC_007146.2 1410901 1411434 R hypothetical protein complement(1410901..1411434) Haemophilus influenzae 86-028NP 3430732 YP_248958.1 CDS NTHI1485 NC_007146.2 1411506 1411922 R hypothetical protein complement(1411506..1411922) Haemophilus influenzae 86-028NP 3430733 YP_248959.1 CDS NTHI1486 NC_007146.2 1411926 1412603 R hypothetical protein complement(1411926..1412603) Haemophilus influenzae 86-028NP 3430734 YP_248960.1 CDS NTHI1487 NC_007146.2 1412622 1413785 R cytosine-specific methyltransferase Bsp6I-like; modification methylase Bsp6I-like complement(1412622..1413785) Haemophilus influenzae 86-028NP 3430735 YP_248961.1 CDS rdgC NC_007146.2 1414391 1415287 R Required for efficient pilin antigenic variation; recombination associated protein complement(1414391..1415287) Haemophilus influenzae 86-028NP 3430736 YP_248962.1 CDS NTHI1489 NC_007146.2 1415412 1416758 R hypothetical protein complement(1415412..1416758) Haemophilus influenzae 86-028NP 3430737 YP_248963.1 CDS ssb3 NC_007146.2 1416820 1417254 R SSB; Helix-destabilizing protein; single-strand binding protein complement(1416820..1417254) Haemophilus influenzae 86-028NP 3430738 YP_248964.1 CDS NTHI1491 NC_007146.2 1417254 1417898 R hypothetical protein complement(1417254..1417898) Haemophilus influenzae 86-028NP 3430739 YP_248965.1 CDS NTHI1492 NC_007146.2 1417879 1418799 R Similar to: YQAK_BACSU; recombinational DNA repair protein, RecE pathway complement(1417879..1418799) Haemophilus influenzae 86-028NP 3430740 YP_248966.1 CDS NTHI1493 NC_007146.2 1418812 1419105 R hypothetical protein complement(1418812..1419105) Haemophilus influenzae 86-028NP 3430741 YP_248967.1 CDS NTHI1494 NC_007146.2 1419102 1419446 R hypothetical protein complement(1419102..1419446) Haemophilus influenzae 86-028NP 3430742 YP_248968.1 CDS NTHI1495 NC_007146.2 1419460 1420197 R adenine-specific methyltransferase DpnIIB-like; modification methylase DpnIIB-like complement(1419460..1420197) Haemophilus influenzae 86-028NP 3430743 YP_248969.1 CDS NTHI1497 NC_007146.2 1420288 1421319 R hypothetical protein complement(1420288..1421319) Haemophilus influenzae 86-028NP 3430744 YP_248970.1 CDS NTHI1498 NC_007146.2 1421309 1421560 R hypothetical protein complement(1421309..1421560) Haemophilus influenzae 86-028NP 3430745 YP_248971.1 CDS NTHI1499 NC_007146.2 1421679 1421990 R hypothetical protein complement(1421679..1421990) Haemophilus influenzae 86-028NP 3430746 YP_248972.1 CDS NTHI1501 NC_007146.2 1422376 1422561 R hypothetical protein complement(1422376..1422561) Haemophilus influenzae 86-028NP 3430747 YP_248973.1 CDS NTHI1502 NC_007146.2 1422722 1423870 R hypothetical protein complement(1422722..1423870) Haemophilus influenzae 86-028NP 3430748 YP_248974.1 CDS NTHI1503 NC_007146.2 1423881 1424741 R hypothetical protein complement(1423881..1424741) Haemophilus influenzae 86-028NP 3430749 YP_248975.1 CDS NTHI1504 NC_007146.2 1424804 1425169 R hypothetical protein complement(1424804..1425169) Haemophilus influenzae 86-028NP 3430750 YP_248976.1 CDS NTHI1505 NC_007146.2 1425171 1425758 R hypothetical protein complement(1425171..1425758) Haemophilus influenzae 86-028NP 3430751 YP_248977.1 CDS NTHI1507 NC_007146.2 1425914 1426099 D hypothetical protein 1425914..1426099 Haemophilus influenzae 86-028NP 3430752 YP_248978.1 CDS NTHI1508 NC_007146.2 1426130 1426558 D hypothetical protein 1426130..1426558 Haemophilus influenzae 86-028NP 3430753 YP_248979.1 CDS NTHI1509 NC_007146.2 1426559 1427068 R hypothetical protein complement(1426559..1427068) Haemophilus influenzae 86-028NP 3430754 YP_248980.1 CDS NTHI1510 NC_007146.2 1427073 1427663 R hypothetical protein complement(1427073..1427663) Haemophilus influenzae 86-028NP 3430755 YP_248981.1 CDS NTHI1511 NC_007146.2 1427660 1428295 R hypothetical protein complement(1427660..1428295) Haemophilus influenzae 86-028NP 3430756 YP_248982.1 CDS NTHI1512 NC_007146.2 1428280 1429062 R hypothetical protein complement(1428280..1429062) Haemophilus influenzae 86-028NP 3430757 YP_248983.1 CDS NTHI1513 NC_007146.2 1429064 1429297 R hypothetical protein complement(1429064..1429297) Haemophilus influenzae 86-028NP 3430758 YP_248984.1 CDS NTHI1515 NC_007146.2 1429343 1429795 R hypothetical protein complement(1429343..1429795) Haemophilus influenzae 86-028NP 3430759 YP_248985.1 CDS NTHI1516 NC_007146.2 1429839 1430045 R hypothetical protein complement(1429839..1430045) Haemophilus influenzae 86-028NP 3430760 YP_248986.1 CDS NTHI1517 NC_007146.2 1430179 1431147 D hypothetical protein 1430179..1431147 Haemophilus influenzae 86-028NP 3430761 YP_248987.1 CDS NTHI1518 NC_007146.2 1431341 1431667 D hypothetical protein 1431341..1431667 Haemophilus influenzae 86-028NP 3430762 YP_248988.1 CDS NTHI1519 NC_007146.2 1431654 1432058 D hypothetical protein 1431654..1432058 Haemophilus influenzae 86-028NP 3430763 YP_248989.1 CDS NTHI1520 NC_007146.2 1432055 1432444 D hypothetical protein 1432055..1432444 Haemophilus influenzae 86-028NP 3430764 YP_248990.1 CDS NTHI1521 NC_007146.2 1432419 1432649 D hypothetical protein 1432419..1432649 Haemophilus influenzae 86-028NP 3430765 YP_248991.1 CDS NTHI1522 NC_007146.2 1432658 1433617 D hypothetical protein 1432658..1433617 Haemophilus influenzae 86-028NP 3430766 YP_248992.1 CDS NTHI1523 NC_007146.2 1433596 1434015 D DNA modification methylase 1433596..1434015 Haemophilus influenzae 86-028NP 3430767 YP_248993.1 CDS NTHI1525 NC_007146.2 1434012 1434233 R hypothetical protein complement(1434012..1434233) Haemophilus influenzae 86-028NP 3430768 YP_248994.1 CDS NTHI1526 NC_007146.2 1434291 1434659 D hypothetical protein 1434291..1434659 Haemophilus influenzae 86-028NP 3430769 YP_248995.1 CDS NTHI1527 NC_007146.2 1434673 1435989 D Similar to: HI1410, YE10_HAEIN; phage terminase large subunit 1434673..1435989 Haemophilus influenzae 86-028NP 3430770 YP_248996.1 CDS NTHI1528 NC_007146.2 1435991 1437307 D hypothetical protein 1435991..1437307 Haemophilus influenzae 86-028NP 3430771 YP_248997.1 CDS NTHI1529 NC_007146.2 1437237 1438049 D Similar to: HI1407; phage Mu protein gp30-like protein 1437237..1438049 Haemophilus influenzae 86-028NP 3430772 YP_248998.1 CDS NTHI1530 NC_007146.2 1438055 1439128 D hypothetical protein 1438055..1439128 Haemophilus influenzae 86-028NP 3430773 YP_248999.1 CDS NTHI1531 NC_007146.2 1439142 1439561 D hypothetical protein 1439142..1439561 Haemophilus influenzae 86-028NP 3430774 YP_249000.1 CDS NTHI1532 NC_007146.2 1439569 1440570 D hypothetical protein 1439569..1440570 Haemophilus influenzae 86-028NP 3430775 YP_249001.1 CDS NTHI1533 NC_007146.2 1440573 1440761 D hypothetical protein 1440573..1440761 Haemophilus influenzae 86-028NP 3430776 YP_249002.1 CDS NTHI1534 NC_007146.2 1440765 1441115 D hypothetical protein 1440765..1441115 Haemophilus influenzae 86-028NP 3430777 YP_249003.1 CDS NTHI1535 NC_007146.2 1441108 1441566 D hypothetical protein 1441108..1441566 Haemophilus influenzae 86-028NP 3430778 YP_249004.1 CDS NTHI1536 NC_007146.2 1441566 1441925 D hypothetical protein 1441566..1441925 Haemophilus influenzae 86-028NP 3430779 YP_249005.1 CDS NTHI1537 NC_007146.2 1441927 1442436 D hypothetical protein 1441927..1442436 Haemophilus influenzae 86-028NP 3430780 YP_249006.1 CDS NTHI1538 NC_007146.2 1442423 1443496 D hypothetical protein 1442423..1443496 Haemophilus influenzae 86-028NP 3430781 YP_249007.1 CDS NTHI1539 NC_007146.2 1443542 1443967 D hypothetical protein 1443542..1443967 Haemophilus influenzae 86-028NP 3430782 YP_249008.1 CDS NTHI1540 NC_007146.2 1443967 1444449 D hypothetical protein 1443967..1444449 Haemophilus influenzae 86-028NP 3430783 YP_249009.1 CDS NTHI1541 NC_007146.2 1444485 1444637 D hypothetical protein 1444485..1444637 Haemophilus influenzae 86-028NP 3430784 YP_249010.1 CDS NTHI1542 NC_007146.2 1444634 1447051 D phage-like minor tail protein 1444634..1447051 Haemophilus influenzae 86-028NP 3430785 YP_249011.1 CDS NTHI1543 NC_007146.2 1447126 1447698 R hypothetical protein complement(1447126..1447698) Haemophilus influenzae 86-028NP 3430786 YP_249012.1 CDS NTHI1544 NC_007146.2 1448006 1448587 D hypothetical protein 1448006..1448587 Haemophilus influenzae 86-028NP 3430787 YP_249013.1 CDS NTHI1546 NC_007146.2 1448584 1448898 D hypothetical protein 1448584..1448898 Haemophilus influenzae 86-028NP 3430788 YP_249014.1 CDS NTHI1547 NC_007146.2 1448895 1449851 D hypothetical protein 1448895..1449851 Haemophilus influenzae 86-028NP 3430789 YP_249015.1 CDS NTHI1548 NC_007146.2 1449854 1450525 D hypothetical protein 1449854..1450525 Haemophilus influenzae 86-028NP 3430790 YP_249016.1 CDS NTHI1549 NC_007146.2 1450522 1450887 D hypothetical protein 1450522..1450887 Haemophilus influenzae 86-028NP 3430791 YP_249017.1 CDS NTHI1550 NC_007146.2 1450880 1452316 D hypothetical protein 1450880..1452316 Haemophilus influenzae 86-028NP 3430792 YP_249018.1 CDS NTHI1551 NC_007146.2 1452325 1452939 D hypothetical protein 1452325..1452939 Haemophilus influenzae 86-028NP 3430793 YP_249019.1 CDS NTHI1552 NC_007146.2 1452949 1455297 D Similar to: HI1403, VPH_BPHP1; tail fiber protein 1452949..1455297 Haemophilus influenzae 86-028NP 3430794 YP_249020.1 CDS NTHI1553 NC_007146.2 1455309 1455911 D Similar to: YO32_BPHP1; hypothetical protein 1455309..1455911 Haemophilus influenzae 86-028NP 3430795 YP_249021.1 CDS NTHI1554 NC_007146.2 1455908 1456408 D hypothetical protein 1455908..1456408 Haemophilus influenzae 86-028NP 3430796 YP_249022.1 CDS NTHI1555 NC_007146.2 1456474 1456923 D Similar to: HI1523, YF23_HAEIN; hypothetical protein 1456474..1456923 Haemophilus influenzae 86-028NP 3430797 YP_249023.1 CDS NTHI1556 NC_007146.2 1456962 1457225 R hypothetical protein complement(1456962..1457225) Haemophilus influenzae 86-028NP 3430798 YP_249024.1 CDS NTHI1560 NC_007146.2 1459009 1459290 R hypothetical protein complement(1459009..1459290) Haemophilus influenzae 86-028NP 3430800 YP_249025.1 CDS NTHI1561 NC_007146.2 1459338 1459523 D Similar to: HI1571, YF71_HAEIN; hypothetical protein 1459338..1459523 Haemophilus influenzae 86-028NP 3430801 YP_249026.1 CDS NTHI1562 NC_007146.2 1459583 1460251 D Similar to: HI1570, YF70_HAEIN; hypothetical protein 1459583..1460251 Haemophilus influenzae 86-028NP 3430802 YP_249027.1 CDS NTHI1563 NC_007146.2 1460353 1460499 D hypothetical protein 1460353..1460499 Haemophilus influenzae 86-028NP 3430803 YP_249028.1 CDS NTHI1564 NC_007146.2 1460532 1461068 D Similar to: HI1563, YFCM_HAEIN; hypothetical protein 1460532..1461068 Haemophilus influenzae 86-028NP 3430804 YP_249029.1 CDS NTHI1565 NC_007146.2 1461269 1461715 D hypothetical protein 1461269..1461715 Haemophilus influenzae 86-028NP 3430805 YP_249030.1 CDS NTHI1566 NC_007146.2 1461715 1461891 D hypothetical protein 1461715..1461891 Haemophilus influenzae 86-028NP 3430806 YP_249031.1 CDS NTHI1567 NC_007146.2 1461903 1462562 D Similar to: YBEQ_ECOLI; hypothetical protein 1461903..1462562 Haemophilus influenzae 86-028NP 3430807 YP_249032.1 CDS NTHI1568 NC_007146.2 1462562 1462738 D hypothetical protein 1462562..1462738 Haemophilus influenzae 86-028NP 3430808 YP_249033.1 CDS NTHI1569 NC_007146.2 1462751 1463305 D hypothetical protein 1462751..1463305 Haemophilus influenzae 86-028NP 3430809 YP_249034.1 CDS NTHI1570 NC_007146.2 1463305 1463481 D hypothetical protein 1463305..1463481 Haemophilus influenzae 86-028NP 3430810 YP_249035.1 CDS NTHI1571 NC_007146.2 1463494 1464045 D hypothetical protein 1463494..1464045 Haemophilus influenzae 86-028NP 3430811 YP_249036.1 CDS prfA NC_007146.2 1464321 1465406 D RF-1; recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1464321..1465406 Haemophilus influenzae 86-028NP 3430812 YP_249037.1 CDS NTHI1573 NC_007146.2 1465429 1465899 D Similar to: HI1560, YF60_HAEIN; hypothetical protein 1465429..1465899 Haemophilus influenzae 86-028NP 3430813 YP_249038.1 CDS hemK NC_007146.2 1465899 1466777 D M.HindHemKP; Similar to: HI1559, HEMK_HAEIN; hypothetical protein 1465899..1466777 Haemophilus influenzae 86-028NP 3430814 YP_249039.1 CDS NTHI1575 NC_007146.2 1466777 1467580 D Similar to: HI1558, YF58_HAEIN; hypothetical protein 1466777..1467580 Haemophilus influenzae 86-028NP 3430815 YP_249040.1 CDS kdsA NC_007146.2 1467595 1468449 D phospho-2-dehydro-3-deoxyoctonate aldolase; 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase; KDO-8-phosphate synthetase; KDO 8-P synthase; KDOPS; catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1467595..1468449 Haemophilus influenzae 86-028NP 3430816 YP_249041.1 CDS NTHI1577 NC_007146.2 1468509 1469456 D Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; glycerate dehydrogenase 1468509..1469456 Haemophilus influenzae 86-028NP 3430817 YP_249042.1 CDS lolC NC_007146.2 1469456 1470637 D Similar to: HI1555, LOLC_HAEIN; lipoprotein releasing system transmembrane protein 1469456..1470637 Haemophilus influenzae 86-028NP 3430818 YP_249043.1 CDS bioA NC_007146.2 1470649 1471941 D 7,8-diamino-pelargonic acid aminotransferase; DAPA aminotransferase; catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 1470649..1471941 Haemophilus influenzae 86-028NP 3430819 YP_249044.1 CDS bioF NC_007146.2 1471950 1473089 D AONS; 8-amino-7-ketopelargonate synthase; 7-keto-8-amino-pelargonic acid synthetase; 7-KAP synthetase; L-alanine--pimelyl CoA ligase; catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 1471950..1473089 Haemophilus influenzae 86-028NP 3430820 YP_249045.1 CDS NTHI1581 NC_007146.2 1473099 1473746 D Similar to: HI1552, YF52_HAEIN; hypothetical protein 1473099..1473746 Haemophilus influenzae 86-028NP 3430821 YP_249046.1 CDS bioC NC_007146.2 1473734 1474516 D Similar to: HI1551, BIOC_HAEIN; biotin synthesis protein BioC 1473734..1474516 Haemophilus influenzae 86-028NP 3430822 YP_249047.1 CDS bioD NC_007146.2 1474526 1475167 D dethiobiotin synthase 2; DTB synthetase 2; DTBS 2; DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1474526..1475167 Haemophilus influenzae 86-028NP 3430823 YP_249048.1 CDS lolD NC_007146.2 1475249 1475932 D Similar to: HI1549, LOLD_HAEIN; lipoprotein releasing system ATP-binding protein LolD 1475249..1475932 Haemophilus influenzae 86-028NP 3430824 YP_249049.1 CDS lolE NC_007146.2 1475932 1477182 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1475932..1477182 Haemophilus influenzae 86-028NP 3430825 YP_249050.1 CDS aroG NC_007146.2 1477401 1478489 D phospho-2-keto-3-deoxyheptonate aldolase; DAHP synthetase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1477401..1478489 Haemophilus influenzae 86-028NP 3430826 YP_249051.1 CDS impA NC_007146.2 1478559 1478999 R Similar to: HI1546, YF46_HAEIN; ImpA complement(1478559..1478999) Haemophilus influenzae 86-028NP 3430827 YP_249052.1 CDS NTHI1589 NC_007146.2 1479284 1480528 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 1479284..1480528 Haemophilus influenzae 86-028NP 3430828 YP_249053.1 CDS NTHI1590 NC_007146.2 1480650 1481258 D Similar to: HI1544, YF44_HAEIN; NAD(P)H oxidoreductase 1480650..1481258 Haemophilus influenzae 86-028NP 3430829 YP_249054.1 CDS NTHI1591 NC_007146.2 1481258 1481812 D Similar to: HI1543, YCDY_HAEIN; component of anaerobic dehydrogenase 1481258..1481812 Haemophilus influenzae 86-028NP 3430830 YP_249055.1 CDS NTHI1592 NC_007146.2 1481859 1482413 R Similar to: HI1542, YDJA_HAEIN; nitroreductase complement(1481859..1482413) Haemophilus influenzae 86-028NP 3430831 YP_249056.1 CDS sppA NC_007146.2 1482511 1484358 D endopeptidase IV; Signal peptide peptidase; Similar to: HI1541, SPPA_HAEIN; endopeptidase IV 1482511..1484358 Haemophilus influenzae 86-028NP 3430832 YP_249057.1 CDS licD NC_007146.2 1484396 1485193 R Similar to: HI1540, LICD_HAEIN; phosphorylcholine transferase complement(1484396..1485193) Haemophilus influenzae 86-028NP 3430833 YP_249058.1 CDS licC NC_007146.2 1485193 1485894 R CTP--phosphocholine cytidylyltransferase involved in choline phosphorylation of cell surface lipooligosaccharide epitopes; Similar to: HI1539, LICC_HAEIN; LicC complement(1485193..1485894) Haemophilus influenzae 86-028NP 3430834 YP_249059.1 CDS licB NC_007146.2 1485891 1486769 R choline uptake protein; Similar to: HI1538, LICB_HAEIN; LicB complement(1485891..1486769) Haemophilus influenzae 86-028NP 3430835 YP_249060.1 CDS licA NC_007146.2 1486769 1487728 R choline kinase involved in LOS biosynthesis; Similar to: HI1537, LIA2_HAEIN; LicA complement(1486769..1487728) Haemophilus influenzae 86-028NP 3430836 YP_249061.1 CDS mnmC NC_007146.2 1487816 1489828 R catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase complement(1487816..1489828) Haemophilus influenzae 86-028NP 3430837 YP_249062.1 CDS fabB NC_007146.2 1489975 1491195 D beta-ketoacyl-ACP synthase I; KAS I; FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1489975..1491195 Haemophilus influenzae 86-028NP 3430838 YP_249063.1 CDS grxA NC_007146.2 1491258 1491521 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1 complement(1491258..1491521) Haemophilus influenzae 86-028NP 3430839 YP_249064.1 CDS rimK NC_007146.2 1491638 1492546 D Similar to: HI1531, RIMK_HAEIN; ribosomal protein S6 modification protein 1491638..1492546 Haemophilus influenzae 86-028NP 3430840 YP_249065.1 CDS gltS NC_007146.2 1492584 1493798 R glutamate permease; Similar to: HI1530, GLTS_HAEIN; Sodium/glutamate symport carrier protein complement(1492584..1493798) Haemophilus influenzae 86-028NP 3430841 YP_249066.1 CDS parC NC_007146.2 1493840 1496083 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(1493840..1496083) Haemophilus influenzae 86-028NP 3430842 YP_249067.1 CDS parE NC_007146.2 1496150 1498048 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(1496150..1498048) Haemophilus influenzae 86-028NP 3430843 YP_249068.1 CDS htrB NC_007146.2 1498122 1499057 R heat shock protein B; Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1498122..1499057) Haemophilus influenzae 86-028NP 3430844 YP_249069.1 CDS rfaE NC_007146.2 1499154 1500584 D catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 1499154..1500584 Haemophilus influenzae 86-028NP 3430845 YP_249070.1 CDS NTHI1611 NC_007146.2 1501255 1501611 R hypothetical protein complement(1501255..1501611) Haemophilus influenzae 86-028NP 3430847 YP_249071.1 CDS uupA2 NC_007146.2 1501722 1502126 D Similar to: HI1300, UUP1_HAEIN; ABC transporter ATP-binding protein 1501722..1502126 Haemophilus influenzae 86-028NP 3430848 YP_249072.1 CDS uppB NC_007146.2 1502123 1502683 D Similar to: HI1342, UUP2_HAEIN; ABC transporter ATP-binding protein 1502123..1502683 Haemophilus influenzae 86-028NP 3430849 YP_249073.1 CDS NTHI1614 NC_007146.2 1502711 1503400 R Similar to: HI1301, YADF_HAEIN; carbonic anhydrase complement(1502711..1503400) Haemophilus influenzae 86-028NP 3430850 YP_249074.2 CDS asnC NC_007146.2 1503476 1504879 R asparagine--tRNA ligase; AsnRS; catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1503476..1504879) Haemophilus influenzae 86-028NP 3430851 YP_249075.1 CDS ribH NC_007146.2 1505106 1505579 D DMRL synthase; lumazine synthase; riboflavin synthase beta chain; RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1505106..1505579 Haemophilus influenzae 86-028NP 3430852 YP_249076.1 CDS nusB NC_007146.2 1505583 1506017 D NusB; Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1505583..1506017 Haemophilus influenzae 86-028NP 3430853 YP_249077.1 CDS thiL NC_007146.2 1506084 1507070 D thiamine-phosphate kinase; Similar to: HI1305, THIL_HAEIN; thiamine-monophosphate kinase 1506084..1507070 Haemophilus influenzae 86-028NP 3430854 YP_249078.1 CDS pgpA NC_007146.2 1507067 1507558 D Similar to: HI1306, PGPA_HAEIN; phosphatidylglycerophosphatase A 1507067..1507558 Haemophilus influenzae 86-028NP 3430855 YP_249079.1 CDS NTHI1620 NC_007146.2 1507558 1508187 D Similar to: HI1307, YD07_HAEIN; threonine efflux protein 1507558..1508187 Haemophilus influenzae 86-028NP 3430856 YP_249080.1 CDS dapB NC_007146.2 1508204 1509016 D DHPR; catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1508204..1509016 Haemophilus influenzae 86-028NP 3430857 YP_249081.1 CDS NTHI1622 NC_007146.2 1509011 1509259 R Similar to: HI1309, YFAE_HAEIN; ferredoxin-like protein complement(1509011..1509259) Haemophilus influenzae 86-028NP 3430858 YP_249082.1 CDS NTHI1623 NC_007146.2 1509305 1510045 D Similar to: HI1310, YD10_HAEIN; hypothetical protein 1509305..1510045 Haemophilus influenzae 86-028NP 3430859 YP_249083.1 CDS pheS NC_007146.2 1510194 1511183 D phenylalanine--tRNA ligase alpha chain; PheRS; catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1510194..1511183 Haemophilus influenzae 86-028NP 3430860 YP_249084.1 CDS pheT NC_007146.2 1511217 1513604 D phenylalanine--tRNA ligase beta chain; PheRS; catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1511217..1513604 Haemophilus influenzae 86-028NP 3430861 YP_249085.1 CDS ihfA NC_007146.2 1513606 1513896 D IHF-alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1513606..1513896 Haemophilus influenzae 86-028NP 3430862 YP_249086.1 CDS NTHI1627 NC_007146.2 1513949 1514434 D Similar to: HI1314, YD14_HAEIN; lipoprotein 1513949..1514434 Haemophilus influenzae 86-028NP 3430863 YP_249087.1 CDS NTHI1628 NC_007146.2 1514443 1515453 D hypothetical protein 1514443..1515453 Haemophilus influenzae 86-028NP 3430864 YP_249088.1 CDS NTHI1629 NC_007146.2 1515512 1515967 D Similar to: 53DR_BPKV4; 5'(3')-deoxyribonucleotidase 1515512..1515967 Haemophilus influenzae 86-028NP 3430865 YP_249089.1 CDS NTHI1630 NC_007146.2 1515951 1516661 D regulatory protein SIR2 family; Similar to: NPD_ACTAC; NAD-dependent deacetylase 1515951..1516661 Haemophilus influenzae 86-028NP 3430866 YP_249090.1 CDS NTHI1631 NC_007146.2 1516710 1517732 R hypothetical protein complement(1516710..1517732) Haemophilus influenzae 86-028NP 3430867 YP_249091.1 CDS ftsK2 NC_007146.2 1517927 1518127 D DNA translocase FtsK 1517927..1518127 Haemophilus influenzae 86-028NP 3430868 YP_249092.1 CDS NTHI1634 NC_007146.2 1518124 1518969 D SIR2 family; NAD-dependent deacetylase 1518124..1518969 Haemophilus influenzae 86-028NP 3430869 YP_249093.1 CDS NTHI1635 NC_007146.2 1518969 1519730 D hypothetical protein 1518969..1519730 Haemophilus influenzae 86-028NP 3430870 YP_249094.1 CDS NTHI1636 NC_007146.2 1519808 1520782 D hypothetical protein 1519808..1520782 Haemophilus influenzae 86-028NP 3430871 YP_249095.1 CDS NTHI1637 NC_007146.2 1520859 1521026 D hypothetical protein 1520859..1521026 Haemophilus influenzae 86-028NP 3430872 YP_249096.1 CDS NTHI1638 NC_007146.2 1521196 1522911 D serine/threonine protein phosphatase family protein 1521196..1522911 Haemophilus influenzae 86-028NP 3430873 YP_249097.1 CDS NTHI1639 NC_007146.2 1522931 1523368 D Similar to: HI1316, YD16_HAEIN; arylsulfatase 1522931..1523368 Haemophilus influenzae 86-028NP 3430874 YP_249098.1 CDS NTHI1640 NC_007146.2 1523450 1524262 D Similar to: HI1317, YD17_HAEIN; aldose 1-epimerase 1523450..1524262 Haemophilus influenzae 86-028NP 3430875 YP_249099.1 CDS infC NC_007146.2 1524530 1524937 D Similar to: HI1318, IF3_HAEIN; translation initiation factor IF-3 1524530..1524937 Haemophilus influenzae 86-028NP 3430876 YP_249100.2 CDS rpmI NC_007146.2 1525148 1525345 D Similar to: HI1319, RL35_HAEIN; 50S ribosomal protein L35 1525148..1525345 Haemophilus influenzae 86-028NP 3430877 YP_249101.1 CDS rplT NC_007146.2 1525411 1525764 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1525411..1525764 Haemophilus influenzae 86-028NP 3430878 YP_249102.1 CDS recB NC_007146.2 1525877 1529512 D Similar to: HI1321, EX5B_HAEIN; exodeoxyribonuclease V subunit beta 1525877..1529512 Haemophilus influenzae 86-028NP 3430879 YP_249103.1 CDS recD NC_007146.2 1529512 1531434 D Similar to: HI1322, EX5A_HAEIN; exodeoxyribonuclease V subunit alpha 1529512..1531434 Haemophilus influenzae 86-028NP 3430880 YP_249104.1 CDS NTHI1647 NC_007146.2 1531503 1531949 R Similar to: HI1323, YD23_HAEIN; hypothetical protein complement(1531503..1531949) Haemophilus influenzae 86-028NP 3430881 YP_249105.1 CDS lonB NC_007146.2 1532046 1533851 D Similar to: HI1324, LONH_HAEIN; protease La 1532046..1533851 Haemophilus influenzae 86-028NP 3430882 YP_249106.1 CDS fabA NC_007146.2 1534020 1534553 D Beta-hydroxydecanoyl thioester dehydrase; catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1534020..1534553 Haemophilus influenzae 86-028NP 3430883 YP_249107.1 CDS NTHI1650 NC_007146.2 1534789 1535517 D Similar to: HI1326, YD26_HAEIN; hypothetical protein 1534789..1535517 Haemophilus influenzae 86-028NP 3430884 YP_249108.1 CDS NTHI1651 NC_007146.2 1535514 1535651 D Similar to: HI1327; hypothetical protein 1535514..1535651 Haemophilus influenzae 86-028NP 3430885 YP_249109.1 CDS rpsO NC_007146.2 1535787 1536056 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1535787..1536056 Haemophilus influenzae 86-028NP 3430886 YP_249110.1 CDS NTHI1653 NC_007146.2 1536128 1536499 R Similar to: HI1328.1, YD2A_HAEIN; transposase-like protein complement(1536128..1536499) Haemophilus influenzae 86-028NP 3430887 YP_249111.1 CDS NTHI1654 NC_007146.2 1536496 1536612 R Similar to: HI1329; hypothetical protein complement(1536496..1536612) Haemophilus influenzae 86-028NP 3430888 YP_249112.1 CDS dacB NC_007146.2 1536828 1538267 R PBP-4; DD-peptidase; DD-carboxypeptidase; DD-endopeptidase; penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase complement(1536828..1538267) Haemophilus influenzae 86-028NP 3430889 YP_249113.1 CDS greA NC_007146.2 1538431 1538907 D transcript cleavage factor greA; necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1538431..1538907 Haemophilus influenzae 86-028NP 3430890 YP_249114.1 CDS NTHI1659 NC_007146.2 1538946 1539245 R Similar to: HI1333, YHBY_HAEIN; RNA-binding protein complement(1538946..1539245) Haemophilus influenzae 86-028NP 3430891 YP_249115.1 CDS rrmJ NC_007146.2 1539372 1540001 D rRNA (uridine-2'-O-)-methyltransferase; 23S rRNA m2U2552 methyltransferase; Cell division protein ftsJ homolog; Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase 1539372..1540001 Haemophilus influenzae 86-028NP 3430892 YP_249116.1 CDS ftsH NC_007146.2 1540092 1541999 D Similar to: HI1335, FTH1_HAEIN; cell division protein FtsH-like protein 1540092..1541999 Haemophilus influenzae 86-028NP 3430893 YP_249117.1 CDS folP NC_007146.2 1542111 1542941 D DHPS; dihydropteroate pyrophosphorylase; Similar to: HI1464, DHPS_HAEIN; dihydropteroate synthase 1542111..1542941 Haemophilus influenzae 86-028NP 3430894 YP_249118.1 CDS glmM NC_007146.2 1542974 1544311 D catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1542974..1544311 Haemophilus influenzae 86-028NP 3430895 YP_249119.1 CDS sixA NC_007146.2 1544370 1544864 D Similar to: HI1462.2, SIXA_HAEIN; phosphohistidine phosphatase SixA-like protein 1544370..1544864 Haemophilus influenzae 86-028NP 3430896 YP_249120.1 CDS NTHI1667 NC_007146.2 1545066 1545641 D Similar to: HI1339, YD39_HAEIN; hypothetical protein 1545066..1545641 Haemophilus influenzae 86-028NP 3430897 YP_249121.1 CDS NTHI1668 NC_007146.2 1545719 1547083 R Similar to: HI1462, YE62_HAEIN; hypothetical protein complement(1545719..1547083) Haemophilus influenzae 86-028NP 3430898 YP_249122.1 CDS NTHI1669 NC_007146.2 1547310 1547450 D hypothetical protein 1547310..1547450 Haemophilus influenzae 86-028NP 3430899 YP_249123.1 CDS NTHI1671 NC_007146.2 1547444 1547596 D hypothetical protein 1547444..1547596 Haemophilus influenzae 86-028NP 3430900 YP_249124.1 CDS NTHI1673 NC_007146.2 1547905 1548501 D Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 1547905..1548501 Haemophilus influenzae 86-028NP 3430902 YP_249125.1 CDS NTHI1674 NC_007146.2 1548511 1548684 D hypothetical protein 1548511..1548684 Haemophilus influenzae 86-028NP 3430903 YP_249126.1 CDS NTHI1675 NC_007146.2 1548779 1549681 R hypothetical protein complement(1548779..1549681) Haemophilus influenzae 86-028NP 3430904 YP_249127.1 CDS msaB NC_007146.2 1549817 1550878 D peptide methionine sulfoxide reductase MsrA; peptide methionine sulfoxide reductase MsrB; protein-methionine-S-oxide reductase; peptide Met(O) reductase; this fusion consists of methionine sulfoxide A reductase at the N-terminus and B at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion; bifunctional methionine sulfoxide reductase A/B protein 1549817..1550878 Haemophilus influenzae 86-028NP 3430905 YP_249128.1 CDS NTHI1678 NC_007146.2 1550890 1551531 D Similar to: HI1454, YE54_HAEIN; hypothetical protein 1550890..1551531 Haemophilus influenzae 86-028NP 3430906 YP_249129.1 CDS NTHI1679 NC_007146.2 1551576 1552046 D Similar to: HI1453, YE53_HAEIN; hypothetical protein 1551576..1552046 Haemophilus influenzae 86-028NP 3430907 YP_249130.1 CDS NTHI1680 NC_007146.2 1552228 1552551 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1552228..1552551) Haemophilus influenzae 86-028NP 3430908 YP_249131.1 CDS moeB NC_007146.2 1552618 1553349 R ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB complement(1552618..1553349) Haemophilus influenzae 86-028NP 3430909 YP_249132.1 CDS moeA NC_007146.2 1553353 1554567 R Similar to: HI1448, MOEA_HAEIN; molybdopterin biosynthesis protein MoeA complement(1553353..1554567) Haemophilus influenzae 86-028NP 3430910 YP_249133.1 CDS folE NC_007146.2 1554705 1555361 D GTP-CH-I; involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1554705..1555361 Haemophilus influenzae 86-028NP 3430911 YP_249134.1 CDS NTHI1684 NC_007146.2 1555365 1555688 D Similar to: HI1446, YCGL_HAEIN; hypothetical protein 1555365..1555688 Haemophilus influenzae 86-028NP 3430912 YP_249135.1 CDS bioD NC_007146.2 1555791 1556519 D dethiobiotin synthase 1; DTB synthetase 1; DTBS 1; DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1555791..1556519 Haemophilus influenzae 86-028NP 3430913 YP_249136.1 CDS metF NC_007146.2 1556608 1557486 R MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase complement(1556608..1557486) Haemophilus influenzae 86-028NP 3430914 YP_249137.1 CDS rplM NC_007146.2 1557949 1558377 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1557949..1558377 Haemophilus influenzae 86-028NP 3430915 YP_249138.1 CDS rpsI NC_007146.2 1558394 1558786 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1558394..1558786 Haemophilus influenzae 86-028NP 3430916 YP_249139.1 CDS sspA NC_007146.2 1558967 1559605 D Similar to: HI1441, SSPA_HAEIN; stringent starvation protein A 1558967..1559605 Haemophilus influenzae 86-028NP 3430917 YP_249140.1 CDS sspB NC_007146.2 1559605 1560057 D Similar to: HI1440, SSPB_HAEIN; ClpXP protease specificity-enhancing factor 1559605..1560057 Haemophilus influenzae 86-028NP 3430918 YP_249141.1 CDS dxs NC_007146.2 1560093 1561970 R 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS; catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(1560093..1561970) Haemophilus influenzae 86-028NP 3430919 YP_249142.1 CDS ispA NC_007146.2 1562012 1562902 R farnesyl-diphosphate synthase; FPP synthase; Similar to: HI1438, ISPA_HAEIN; geranyltranstransferase complement(1562012..1562902) Haemophilus influenzae 86-028NP 3430920 YP_249143.1 CDS xseB NC_007146.2 1562902 1563156 R exonuclease VII small subunit; catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(1562902..1563156) Haemophilus influenzae 86-028NP 3430921 YP_249144.1 CDS thiI NC_007146.2 1563315 1564772 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 1563315..1564772 Haemophilus influenzae 86-028NP 3430922 YP_249145.1 CDS NTHI1695 NC_007146.2 1564787 1565107 D Similar to: HI1436, YQCC_HAEIN; hypothetical protein 1564787..1565107 Haemophilus influenzae 86-028NP 3430923 YP_249146.1 CDS truC NC_007146.2 1565101 1565820 D pseudouridylate synthase; uracil hydrolyase; catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 1565101..1565820 Haemophilus influenzae 86-028NP 3430924 YP_249147.1 CDS NTHI1697 NC_007146.2 1565813 1565971 D Similar to: HI1434.2; hypothetical protein 1565813..1565971 Haemophilus influenzae 86-028NP 3430925 YP_249148.1 CDS cspD NC_007146.2 1566120 1566338 D Similar to: HI1434.1, CSPD_HAEIN; cold shock-like protein CspD 1566120..1566338 Haemophilus influenzae 86-028NP 3430926 YP_249149.1 CDS NTHI1699 NC_007146.2 1566477 1566953 R Similar to: HI1434, YBAK_HAEIN; predicted oligonucleotide binding domain; hypothetical protein complement(1566477..1566953) Haemophilus influenzae 86-028NP 3430927 YP_249150.1 CDS usg NC_007146.2 1567012 1567965 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1567012..1567965 Haemophilus influenzae 86-028NP 3430928 YP_249151.1 CDS trpA NC_007146.2 1568109 1568915 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1568109..1568915) Haemophilus influenzae 86-028NP 3430929 YP_249152.1 CDS trpB NC_007146.2 1568915 1570108 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1568915..1570108) Haemophilus influenzae 86-028NP 3430930 YP_249153.1 CDS NTHI1703 NC_007146.2 1570125 1570883 R Similar to: HI1430, YDFG_HAEIN; oxidoreductase complement(1570125..1570883) Haemophilus influenzae 86-028NP 3430931 YP_249154.1 CDS purM NC_007146.2 1571063 1572097 D AIRS; phosphoribosyl-aminoimidazole synthetase; AIR synthase; catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1571063..1572097 Haemophilus influenzae 86-028NP 3430932 YP_249155.1 CDS purN NC_007146.2 1572152 1572790 D GART; GAR transformylase; 5'-phosphoribosylglycinamide transformylase; glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 1572152..1572790 Haemophilus influenzae 86-028NP 3430933 YP_249156.1 CDS NTHI1707 NC_007146.2 1572874 1573710 R Similar to: HI1427, YE27_HAEIN; ABC transporter periplasmic protein complement(1572874..1573710) Haemophilus influenzae 86-028NP 3430934 YP_249157.2 CDS uspE NC_007146.2 1573908 1574837 R with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE complement(1573908..1574837) Haemophilus influenzae 86-028NP 3430935 YP_249158.1 CDS fnr NC_007146.2 1574959 1575732 R Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator complement(1574959..1575732) Haemophilus influenzae 86-028NP 3430936 YP_249159.1 CDS NTHI1711 NC_007146.2 1576350 1576706 D Similar to: HI1424, YE24_HAEIN; integrase/recombinase 1576350..1576706 Haemophilus influenzae 86-028NP 3430938 YP_249160.1 CDS NTHI1712 NC_007146.2 1576591 1576980 R Similar to: HI1423, YE23_HAEIN; hypothetical protein complement(1576591..1576980) Haemophilus influenzae 86-028NP 3430939 YP_249161.1 CDS NTHI1713 NC_007146.2 1577285 1577536 R Similar to: HI1422, YE22_HAEIN; phage anti-repressor protein complement(1577285..1577536) Haemophilus influenzae 86-028NP 3430940 YP_249162.1 CDS NTHI1714 NC_007146.2 1577874 1579145 R hypothetical protein complement(1577874..1579145) Haemophilus influenzae 86-028NP 3430941 YP_249163.1 CDS NTHI1715 NC_007146.2 1579746 1579949 D hypothetical protein 1579746..1579949 Haemophilus influenzae 86-028NP 3430942 YP_249164.1 CDS NTHI1716 NC_007146.2 1579927 1580085 R hypothetical protein complement(1579927..1580085) Haemophilus influenzae 86-028NP 3430943 YP_249165.1 CDS NTHI1717 NC_007146.2 1580413 1580634 R hypothetical protein complement(1580413..1580634) Haemophilus influenzae 86-028NP 3430944 YP_249166.1 CDS NTHI1718 NC_007146.2 1581561 1581896 R hypothetical protein complement(1581561..1581896) Haemophilus influenzae 86-028NP 3430945 YP_249167.1 CDS NTHI1719 NC_007146.2 1581899 1582978 R hypothetical protein complement(1581899..1582978) Haemophilus influenzae 86-028NP 3430946 YP_249168.1 CDS NTHI1720 NC_007146.2 1583030 1583728 R Similar to: RPC1_BPPH8; transcriptional regulator complement(1583030..1583728) Haemophilus influenzae 86-028NP 3430947 YP_249169.1 CDS NTHI1721 NC_007146.2 1583839 1584027 D hypothetical protein 1583839..1584027 Haemophilus influenzae 86-028NP 3430948 YP_249170.1 CDS NTHI1722 NC_007146.2 1584076 1584516 D hypothetical protein 1584076..1584516 Haemophilus influenzae 86-028NP 3430949 YP_249171.1 CDS NTHI1723 NC_007146.2 1584565 1585239 D hypothetical protein 1584565..1585239 Haemophilus influenzae 86-028NP 3430950 YP_249172.1 CDS NTHI1724 NC_007146.2 1585236 1585994 D hypothetical protein 1585236..1585994 Haemophilus influenzae 86-028NP 3430951 YP_249173.1 CDS NTHI1725 NC_007146.2 1585979 1586620 D hypothetical protein 1585979..1586620 Haemophilus influenzae 86-028NP 3430952 YP_249174.1 CDS NTHI1726 NC_007146.2 1586617 1586841 D hypothetical protein 1586617..1586841 Haemophilus influenzae 86-028NP 3430953 YP_249175.1 CDS ninB NC_007146.2 1586878 1587294 D recombination protein NinB 1586878..1587294 Haemophilus influenzae 86-028NP 3430954 YP_249176.1 CDS ninG NC_007146.2 1587562 1587951 D recombination protein NinG-like protein 1587562..1587951 Haemophilus influenzae 86-028NP 3430955 YP_249177.1 CDS NTHI1729 NC_007146.2 1587971 1588600 D hypothetical protein 1587971..1588600 Haemophilus influenzae 86-028NP 3430956 YP_249178.1 CDS NTHI1730 NC_007146.2 1588724 1589002 D Similar to: HI1421, YE21_HAEIN; hypothetical protein 1588724..1589002 Haemophilus influenzae 86-028NP 3430957 YP_249179.1 CDS NTHI1731 NC_007146.2 1589052 1590029 R hypothetical protein complement(1589052..1590029) Haemophilus influenzae 86-028NP 3430958 YP_249180.1 CDS NTHI1733 NC_007146.2 1590258 1591043 D Similar to: HI1418, YE18_HAEIN; hypothetical protein 1590258..1591043 Haemophilus influenzae 86-028NP 3430959 YP_249181.1 CDS NTHI1734 NC_007146.2 1591074 1591256 D hypothetical protein 1591074..1591256 Haemophilus influenzae 86-028NP 3430960 YP_249182.1 CDS NTHI1735 NC_007146.2 1591380 1591736 D Similar to: HI1416, YE16_HAEIN; hypothetical protein 1591380..1591736 Haemophilus influenzae 86-028NP 3430961 YP_249183.1 CDS NTHI1736 NC_007146.2 1591816 1592307 D Similar to: HI1415, YE15_HAEIN; hypothetical protein 1591816..1592307 Haemophilus influenzae 86-028NP 3430962 YP_249184.1 CDS NTHI1737 NC_007146.2 1592300 1592623 D hypothetical protein 1592300..1592623 Haemophilus influenzae 86-028NP 3430963 YP_249185.1 CDS NTHI1738 NC_007146.2 1592535 1592816 D Similar to: HI1413, YE13_HAEIN; hypothetical protein 1592535..1592816 Haemophilus influenzae 86-028NP 3430964 YP_249186.1 CDS NTHI1739 NC_007146.2 1592818 1593096 R hypothetical protein complement(1592818..1593096) Haemophilus influenzae 86-028NP 3430965 YP_249187.1 CDS NTHI1740 NC_007146.2 1593141 1593653 D Similar to: HI1411, YE11_HAEIN; hypothetical protein 1593141..1593653 Haemophilus influenzae 86-028NP 3430966 YP_249188.1 CDS NTHI1741 NC_007146.2 1593640 1594983 D Similar to: HI1410, YE10_HAEIN; phage terminase large subunit 1593640..1594983 Haemophilus influenzae 86-028NP 3430967 YP_249189.1 CDS NTHI1742 NC_007146.2 1594985 1596319 D Similar to: HI1409, YE09_HAEIN; hypothetical protein 1594985..1596319 Haemophilus influenzae 86-028NP 3430968 YP_249190.1 CDS traN NC_007146.2 1596348 1597529 D Similar to: HI1407, YE07_HAEIN; phage Mu protein gp30-like protein 1596348..1597529 Haemophilus influenzae 86-028NP 3430969 YP_249191.1 CDS NTHI1744 NC_007146.2 1597675 1597851 D Similar to: HI1405; hypothetical protein 1597675..1597851 Haemophilus influenzae 86-028NP 3430970 YP_249192.1 CDS pyrD NC_007146.2 1598015 1599034 D dihydroorotate oxidase; DHodehase; DHODase; DHOD; catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1598015..1599034 Haemophilus influenzae 86-028NP 3430971 YP_249193.1 CDS trpH NC_007146.2 1599034 1599858 D Similar to: HI1400, TRPH_HAEIN; TrpH 1599034..1599858 Haemophilus influenzae 86-028NP 3430972 YP_249194.1 CDS NTHI1748 NC_007146.2 1599957 1600565 R Similar to: HI1399, YD99_HAEIN; hypothetical protein complement(1599957..1600565) Haemophilus influenzae 86-028NP 3430973 YP_249195.1 CDS fumC NC_007146.2 1600693 1602087 R fumarase; class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1600693..1602087) Haemophilus influenzae 86-028NP 3430974 YP_249196.1 CDS NTHI1750 NC_007146.2 1602237 1603175 R glycosyl transferase family protein complement(1602237..1603175) Haemophilus influenzae 86-028NP 3430975 YP_249197.1 CDS holC NC_007146.2 1603831 1604265 D binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 1603831..1604265 Haemophilus influenzae 86-028NP 3430977 YP_249198.1 CDS NTHI1754 NC_007146.2 1604350 1604520 D Similar to: HI1396, YD96_HAEIN; hypothetical protein 1604350..1604520 Haemophilus influenzae 86-028NP 3430978 YP_249199.1 CDS NTHI1755 NC_007146.2 1604533 1604907 D Similar to: HI1395, YD95_HAEIN; hypothetical protein 1604533..1604907 Haemophilus influenzae 86-028NP 3430979 YP_249200.1 CDS NTHI1756 NC_007146.2 1604935 1605102 D hypothetical protein 1604935..1605102 Haemophilus influenzae 86-028NP 3430980 YP_249201.1 CDS NTHI1757 NC_007146.2 1605129 1605443 D Similar to: HI1394, YD94_HAEIN; hypothetical protein 1605129..1605443 Haemophilus influenzae 86-028NP 3430981 YP_249202.1 CDS NTHI1758 NC_007146.2 1605487 1605888 D hypothetical protein 1605487..1605888 Haemophilus influenzae 86-028NP 3430982 YP_249203.1 CDS valS NC_007146.2 1605940 1608804 D valine--tRNA ligase; ValRS; valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1605940..1608804 Haemophilus influenzae 86-028NP 3430983 YP_249204.1 CDS NTHI1762 NC_007146.2 1608839 1608946 R hypothetical protein complement(1608839..1608946) Haemophilus influenzae 86-028NP 3430984 YP_249205.1 CDS trpC NC_007146.2 1609234 1610667 R IGPS; PRAI; monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1609234..1610667) Haemophilus influenzae 86-028NP 3430985 YP_249206.1 CDS trpD NC_007146.2 1610705 1611706 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1610705..1611706) Haemophilus influenzae 86-028NP 3430986 YP_249207.1 CDS NTHI1765 NC_007146.2 1611759 1612145 R Similar to: HI1388.1, YD8A_HAEIN; hypothetical protein complement(1611759..1612145) Haemophilus influenzae 86-028NP 3430987 YP_249208.1 CDS trpG NC_007146.2 1612194 1612781 R glutamine amido-transferase; TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(1612194..1612781) Haemophilus influenzae 86-028NP 3430988 YP_249209.1 CDS trpE NC_007146.2 1612794 1614350 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1612794..1614350) Haemophilus influenzae 86-028NP 3430989 YP_249210.1 CDS ftnB NC_007146.2 1615485 1615982 R Similar to: HI1385, FTN2_HAEIN; ferritin complement(1615485..1615982) Haemophilus influenzae 86-028NP 3430991 YP_249211.1 CDS ftnA NC_007146.2 1615998 1616546 R Similar to: HI1384, FTN1_HAEIN; ferritin complement(1615998..1616546) Haemophilus influenzae 86-028NP 3430992 YP_249212.1 CDS pstS NC_007146.2 1616989 1618008 D PBP; Similar to: HI1383, PSTS_HAEIN; phosphate-binding periplasmic protein PstS 1616989..1618008 Haemophilus influenzae 86-028NP 3430993 YP_249213.1 CDS pstC NC_007146.2 1618100 1619047 D Similar to: HI1382, PSTC_HAEIN; phosphate transport system permease protein PstC 1618100..1619047 Haemophilus influenzae 86-028NP 3430994 YP_249214.1 CDS pstA NC_007146.2 1619049 1619897 D Similar to: HI1381, PSTA_HAEIN; phosphate transport system permease protein PstA 1619049..1619897 Haemophilus influenzae 86-028NP 3430995 YP_249215.1 CDS pstB NC_007146.2 1619907 1620674 D phosphate-transporting ATPase; ABC phosphate transporter; ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1619907..1620674 Haemophilus influenzae 86-028NP 3430996 YP_249216.1 CDS phoB NC_007146.2 1620771 1621466 D Similar to: HI1379, PHOB_HAEIN; phosphate regulon transcriptional regulatory protein PhoB 1620771..1621466 Haemophilus influenzae 86-028NP 3430997 YP_249217.1 CDS phoR NC_007146.2 1621463 1622740 D Similar to: HI1378, PHOR_HAEIN; phosphate regulon sensor protein PhoR 1621463..1622740 Haemophilus influenzae 86-028NP 3430998 YP_249218.1 CDS sbcB NC_007146.2 1623432 1624853 R exonuclease I; DNA deoxyribophosphodiesterase; dRPase; Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I complement(1623432..1624853) Haemophilus influenzae 86-028NP 3430999 YP_249219.1 CDS NTHI1781 NC_007146.2 1624866 1625741 R Similar to: HI1376, YD76_HAEIN; hypothetical protein complement(1624866..1625741) Haemophilus influenzae 86-028NP 3431000 YP_249220.1 CDS NTHI1782 NC_007146.2 1625745 1626653 R Similar to: HI1375, YD75_HAEIN; hypothetical protein complement(1625745..1626653) Haemophilus influenzae 86-028NP 3431001 YP_249221.1 CDS mukB NC_007146.2 1626723 1631255 R SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB complement(1626723..1631255) Haemophilus influenzae 86-028NP 3431002 YP_249222.1 CDS NTHI1785 NC_007146.2 1631255 1631989 R acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E complement(1631255..1631989) Haemophilus influenzae 86-028NP 3431003 YP_249223.1 CDS haeIIR NC_007146.2 1631993 1633051 R endonuclease HaeII; R.HaeII; Similar to: T2H2_HAEAE; type II restriction enzyme HaeII complement(1631993..1633051) Haemophilus influenzae 86-028NP 3431004 YP_249224.1 CDS haeIIM NC_007146.2 1633054 1634010 R cytosine-specific methyltransferase HaeII; M.HaeII; Similar to: MTH2_HAEAE; modification methylase HaeII complement(1633054..1634010) Haemophilus influenzae 86-028NP 3431005 YP_249225.1 CDS mukF NC_007146.2 1634023 1635450 R acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F complement(1634023..1635450) Haemophilus influenzae 86-028NP 3431006 YP_249226.1 CDS NTHI1789 NC_007146.2 1635507 1636439 D TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1635507..1636439 Haemophilus influenzae 86-028NP 3431007 YP_249227.1 CDS NTHI1790 NC_007146.2 1636441 1636770 D Similar to: HI1371, YCCK_HAEIN; dissimilatory sulfite reductase, desulfoviridin subunit gamma 1636441..1636770 Haemophilus influenzae 86-028NP 3431008 YP_249228.1 CDS mop NC_007146.2 1636878 1637087 D Similar to: HI1370, MOP_HAEIN; molybdenum-pterin binding protein 1636878..1637087 Haemophilus influenzae 86-028NP 3431009 YP_249229.1 CDS pqqL NC_007146.2 1639787 1642567 D Similar to: HI1368, PQQL_HAEIN; zinc protease 1639787..1642567 Haemophilus influenzae 86-028NP 3431011 YP_249230.1 CDS thrS NC_007146.2 1642690 1644621 R threonine--tRNA ligase; ThrRS; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase complement(1642690..1644621) Haemophilus influenzae 86-028NP 3431012 YP_249231.1 CDS acpD NC_007146.2 1644905 1645489 D ACP phosphodiesterase; Similar to: HI1366, ACPD_HAEIN; ACP phosphodieterase 1644905..1645489 Haemophilus influenzae 86-028NP 3431013 YP_249232.1 CDS topA NC_007146.2 1645566 1648172 R Omega-protein; relaxing enzyme; untwisting enzyme; swivelase; catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I complement(1645566..1648172) Haemophilus influenzae 86-028NP 3431014 YP_249233.1 CDS NTHI1800 NC_007146.2 1648268 1649185 D Similar to: HI1364, YHCS_HAEIN; HTH-type transcriptional regulator 1648268..1649185 Haemophilus influenzae 86-028NP 3431015 YP_249234.1 CDS pntB NC_007146.2 1649249 1650673 R pyridine nucleotide transhydrogenase subunit beta; nicotinamide nucleotide transhydrogenase subunit beta; catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(1649249..1650673) Haemophilus influenzae 86-028NP 3431016 YP_249235.1 CDS pntA NC_007146.2 1650684 1652222 R pyridine nucleotide transhydrogenase subunit alpha; nicotinamide nucleotide transhydrogenase subunit alpha; forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(1650684..1652222) Haemophilus influenzae 86-028NP 3431017 YP_249236.1 CDS glgP NC_007146.2 1652483 1654948 R Similar to: HI1361, PHSG_HAEIN; glycogen phosphorylase complement(1652483..1654948) Haemophilus influenzae 86-028NP 3431018 YP_249237.1 CDS glgA NC_007146.2 1655195 1656625 R Starch [bacterial glycogen] synthase; catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(1655195..1656625) Haemophilus influenzae 86-028NP 3431019 YP_249238.1 CDS glgC NC_007146.2 1656733 1658067 R ADP-glucose synthase; ADP-glucose pyrophosphorylase; ADPGlc PPase; catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(1656733..1658067) Haemophilus influenzae 86-028NP 3431020 YP_249239.1 CDS glgX NC_007146.2 1658057 1660033 R Similar to: HI1358, GLGX_HAEIN; glycogen operon protein GlgX complement(1658057..1660033) Haemophilus influenzae 86-028NP 3431021 YP_249240.1 CDS glgB NC_007146.2 1660132 1662324 R glycogen branching enzyme; BE; 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase; catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme complement(1660132..1662324) Haemophilus influenzae 86-028NP 3431022 YP_249241.1 CDS malQ NC_007146.2 1662334 1664433 R amylomaltase; disproportionating enzyme; D-enzyme; Similar to: HI1356, MALQ_HAEIN; 4-alpha-glucanotransferase complement(1662334..1664433) Haemophilus influenzae 86-028NP 3431023 YP_249242.1 CDS NTHI1811 NC_007146.2 1664495 1664959 R Similar to: HI1355, YD55_HAEIN; hypothetical protein complement(1664495..1664959) Haemophilus influenzae 86-028NP 3431024 YP_249243.1 CDS glnS NC_007146.2 1665025 1666698 R glutamine--tRNA ligase; GlnRS; catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase complement(1665025..1666698) Haemophilus influenzae 86-028NP 3431025 YP_249244.1 CDS cafA NC_007146.2 1667118 1668593 R RNase G; cytoplasmic axial filament protein; involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(1667118..1668593) Haemophilus influenzae 86-028NP 3431026 YP_249245.1 CDS putP NC_007146.2 1668709 1670223 D proline permease; Similar to: HI1352, PUTP_HAEIN; sodium/proline symporter 1668709..1670223 Haemophilus influenzae 86-028NP 3431027 YP_249246.1 CDS NTHI1815 NC_007146.2 1670220 1671185 D Similar to: HI1351, YECP_HAEIN; hypothetical protein 1670220..1671185 Haemophilus influenzae 86-028NP 3431028 YP_249247.1 CDS cdd NC_007146.2 1671228 1672106 R cytidine aminohydrolase; CDA; Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase complement(1671228..1672106) Haemophilus influenzae 86-028NP 3431029 YP_249248.1 CDS NTHI1817 NC_007146.2 1672380 1672862 D Similar to: HI1349, YD49_HAEIN; DNA-binding ferritin-like protein 1672380..1672862 Haemophilus influenzae 86-028NP 3431030 YP_249249.1 CDS pepT NC_007146.2 1673434 1674672 R tripeptide aminopeptidase; aminotripeptidase; tripeptidase; catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T complement(1673434..1674672) Haemophilus influenzae 86-028NP 3431031 YP_249250.1 CDS potA NC_007146.2 1674942 1676087 D functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase protein 1674942..1676087 Haemophilus influenzae 86-028NP 3431032 YP_249251.1 CDS potB NC_007146.2 1676071 1676931 D can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1676071..1676931 Haemophilus influenzae 86-028NP 3431033 YP_249252.1 CDS potC NC_007146.2 1676931 1677701 D can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1676931..1677701 Haemophilus influenzae 86-028NP 3431034 YP_249253.1 CDS potD1 NC_007146.2 1677748 1678914 D SPBP; Similar to: HI1344, POT1_HAEIN; spermidine/putrescine-binding periplasmic protein 1 1677748..1678914 Haemophilus influenzae 86-028NP 3431035 YP_249254.1 CDS uupA NC_007146.2 1678995 1680938 R Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase complement(1678995..1680938) Haemophilus influenzae 86-028NP 3431036 YP_249255.1 CDS NTHI1825 NC_007146.2 1681032 1682417 R dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein complement(1681032..1682417) Haemophilus influenzae 86-028NP 3431037 YP_249256.1 CDS NTHI1826 NC_007146.2 1682510 1683205 R Similar to: HI1298, YOHK_HAEIN; effector of murein hydrolase complement(1682510..1683205) Haemophilus influenzae 86-028NP 3431038 YP_249257.1 CDS NTHI1827 NC_007146.2 1683224 1683646 R Similar to: HI1297, YOHJ_HAEIN; hypothetical protein complement(1683224..1683646) Haemophilus influenzae 86-028NP 3431039 YP_249258.1 CDS NTHI1828 NC_007146.2 1683761 1684243 D Similar to: HI1296, YC96_HAEIN; micrococcal nuclease-like protein 1683761..1684243 Haemophilus influenzae 86-028NP 3431040 YP_249259.1 CDS nifS NC_007146.2 1684245 1685444 D Similar to: HI1295, CSD_HAEIN; selenocysteine lyase 1684245..1685444 Haemophilus influenzae 86-028NP 3431041 YP_249260.1 CDS NTHI1830 NC_007146.2 1685441 1685821 D Similar to: HI1293, YC93_HAEIN; hypothetical protein 1685441..1685821 Haemophilus influenzae 86-028NP 3431042 YP_249261.1 CDS NTHI1831 NC_007146.2 1685812 1686609 D Similar to: HI1292, YC92_HAEIN; hypothetical protein 1685812..1686609 Haemophilus influenzae 86-028NP 3431043 YP_249262.1 CDS queF NC_007146.2 1686653 1687492 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1686653..1687492 Haemophilus influenzae 86-028NP 3431044 YP_249263.1 CDS tyrA NC_007146.2 1687525 1688649 R CM; PDH; catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(1687525..1688649) Haemophilus influenzae 86-028NP 3431045 YP_249264.1 CDS truB NC_007146.2 1688739 1689659 R tRNA pseudouridine 55 synthase; Psi55 synthase; pseudouridylate synthase; Uracil hydrolyase; catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(1688739..1689659) Haemophilus influenzae 86-028NP 3431046 YP_249265.1 CDS rbfA NC_007146.2 1689659 1690045 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(1689659..1690045) Haemophilus influenzae 86-028NP 3431047 YP_249266.1 CDS hsdM3 NC_007146.2 1690210 1691880 D M.HindVIIP; Similar to: HI1287, T1MH_HAEIN; type I restriction enzyme HindVIIP M protein 1690210..1691880 Haemophilus influenzae 86-028NP 3431048 YP_249267.1 CDS hsdS3 NC_007146.2 1691873 1693138 D S protein; S.HindVIIP; Similar to: HI1286, T1SH_HAEIN; type I restriction enzyme HindVIIP specificity protein 1691873..1693138 Haemophilus influenzae 86-028NP 3431049 YP_249268.1 CDS NTHI1841 NC_007146.2 1693131 1694177 D hypothetical protein 1693131..1694177 Haemophilus influenzae 86-028NP 3431050 YP_249269.1 CDS hsdR3 NC_007146.2 1694179 1697346 D Similar to: HI1285, T1RH_HAEIN; type I restriction enzyme HindVIIP R protein 1694179..1697346 Haemophilus influenzae 86-028NP 3431107 YP_249270.1 CDS infB NC_007146.2 1697425 1699959 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(1697425..1699959) Haemophilus influenzae 86-028NP 3431108 YP_249271.1 CDS nusA NC_007146.2 1699971 1701458 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(1699971..1701458) Haemophilus influenzae 86-028NP 3431109 YP_249272.1 CDS NTHI1846 NC_007146.2 1701475 1701930 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(1701475..1701930) Haemophilus influenzae 86-028NP 3431110 YP_249273.1 CDS NTHI1849 NC_007146.2 1703591 1704355 R hypothetical protein complement(1703591..1704355) Haemophilus influenzae 86-028NP 3431112 YP_249274.1 CDS NTHI1850 NC_007146.2 1704359 1704886 R hypothetical protein complement(1704359..1704886) Haemophilus influenzae 86-028NP 3431113 YP_249275.1 CDS NTHI1851 NC_007146.2 1704896 1706035 R hypothetical protein complement(1704896..1706035) Haemophilus influenzae 86-028NP 3431114 YP_249276.1 CDS NTHI1852 NC_007146.2 1706052 1706420 R hypothetical protein complement(1706052..1706420) Haemophilus influenzae 86-028NP 3431115 YP_249277.1 CDS NTHI1853 NC_007146.2 1706434 1707255 R hypothetical protein complement(1706434..1707255) Haemophilus influenzae 86-028NP 3431116 YP_249278.1 CDS NTHI1855 NC_007146.2 1707312 1707815 R hypothetical protein complement(1707312..1707815) Haemophilus influenzae 86-028NP 3431117 YP_249279.1 CDS NTHI1856 NC_007146.2 1707812 1708414 R Similar to: YO32_BPHP1; hypothetical protein complement(1707812..1708414) Haemophilus influenzae 86-028NP 3431118 YP_249280.1 CDS NTHI1857 NC_007146.2 1708426 1710948 R Similar to: HI1403, VPH_BPHP1; tail fiber protein complement(1708426..1710948) Haemophilus influenzae 86-028NP 3431119 YP_249281.1 CDS NTHI1858 NC_007146.2 1710957 1711493 R Similar to: VPI_BPP2; bacteriophage P2-related tail formation protein gpI complement(1710957..1711493) Haemophilus influenzae 86-028NP 3431120 YP_249282.1 CDS NTHI1860 NC_007146.2 1711483 1712397 R Similar to: VPJ_BPP2; phage-like baseplate assembly protein complement(1711483..1712397) Haemophilus influenzae 86-028NP 3431121 YP_249283.1 CDS NTHI1861 NC_007146.2 1712394 1712732 R baseplate assembly protein W complement(1712394..1712732) Haemophilus influenzae 86-028NP 3431122 YP_249284.1 CDS NTHI1862 NC_007146.2 1712734 1713333 R phage P2-like baseplate assembly protein complement(1712734..1713333) Haemophilus influenzae 86-028NP 3431123 YP_249285.1 CDS NTHI1863 NC_007146.2 1713437 1713865 R hypothetical protein complement(1713437..1713865) Haemophilus influenzae 86-028NP 3431124 YP_249286.1 CDS NTHI1864 NC_007146.2 1713874 1714431 R hypothetical protein complement(1713874..1714431) Haemophilus influenzae 86-028NP 3431125 YP_249287.1 CDS NTHI1865 NC_007146.2 1714529 1714981 R hypothetical protein complement(1714529..1714981) Haemophilus influenzae 86-028NP 3431126 YP_249288.1 CDS NTHI1866 NC_007146.2 1714959 1715159 R hypothetical protein complement(1714959..1715159) Haemophilus influenzae 86-028NP 3431127 YP_249289.1 CDS NTHI1867 NC_007146.2 1715203 1717167 R phage-like tail protein complement(1715203..1717167) Haemophilus influenzae 86-028NP 3431128 YP_249290.1 CDS NTHI1869 NC_007146.2 1717210 1717977 R hypothetical protein complement(1717210..1717977) Haemophilus influenzae 86-028NP 3431129 YP_249291.1 CDS NTHI1870 NC_007146.2 1718022 1718360 D hypothetical protein 1718022..1718360 Haemophilus influenzae 86-028NP 3431130 YP_249292.1 CDS NTHI1871 NC_007146.2 1718371 1718553 R hypothetical protein complement(1718371..1718553) Haemophilus influenzae 86-028NP 3431131 YP_249293.1 CDS NTHI1872 NC_007146.2 1718657 1719004 D hypothetical protein 1718657..1719004 Haemophilus influenzae 86-028NP 3431132 YP_249294.1 CDS NTHI1873 NC_007146.2 1719005 1719466 R bacteriophage tail completion protein gpS-like protein complement(1719005..1719466) Haemophilus influenzae 86-028NP 3431133 YP_249295.1 CDS NTHI1874 NC_007146.2 1719466 1719852 R bacteriophage tail completion protein gpR-like protein complement(1719466..1719852) Haemophilus influenzae 86-028NP 3431134 YP_249296.1 CDS NTHI1875 NC_007146.2 1719902 1720009 R hypothetical protein complement(1719902..1720009) Haemophilus influenzae 86-028NP 3431135 YP_249297.1 CDS NTHI1876 NC_007146.2 1720042 1720164 R hypothetical protein complement(1720042..1720164) Haemophilus influenzae 86-028NP 3431136 YP_249298.1 CDS NTHI1878 NC_007146.2 1720161 1720376 R DnaK suppressor protein complement(1720161..1720376) Haemophilus influenzae 86-028NP 3431137 YP_249299.1 CDS NTHI1879 NC_007146.2 1720551 1720901 R hypothetical protein complement(1720551..1720901) Haemophilus influenzae 86-028NP 3431138 YP_249300.1 CDS NTHI1880 NC_007146.2 1720886 1721404 R Lysis protein; muramidase; endolysin; Similar to: LYCV_BPP1; phage-like lysozyme complement(1720886..1721404) Haemophilus influenzae 86-028NP 3431139 YP_249301.1 CDS NTHI1881 NC_007146.2 1721397 1721618 R hypothetical protein complement(1721397..1721618) Haemophilus influenzae 86-028NP 3431140 YP_249302.1 CDS NTHI1882 NC_007146.2 1721620 1721829 R hypothetical protein complement(1721620..1721829) Haemophilus influenzae 86-028NP 3431141 YP_249303.1 CDS NTHI1883 NC_007146.2 1721829 1722335 R hypothetical protein complement(1721829..1722335) Haemophilus influenzae 86-028NP 3431142 YP_249304.1 CDS NTHI1884 NC_007146.2 1722629 1723279 R Similar to: VPM_BPP2; terminase, endonuclease subunit complement(1722629..1723279) Haemophilus influenzae 86-028NP 3431143 YP_249305.1 CDS NTHI1885 NC_007146.2 1723291 1724340 R Similar to: VPN_BPP2; major capsid protein complement(1723291..1724340) Haemophilus influenzae 86-028NP 3431144 YP_249306.1 CDS NTHI1887 NC_007146.2 1724361 1725176 R Similar to: VPO_BPP2; capsid scaffolding protein complement(1724361..1725176) Haemophilus influenzae 86-028NP 3431145 YP_249307.1 CDS NTHI1888 NC_007146.2 1725341 1727122 D Similar to: VPP_BPP2; terminase, ATPase subunit 1725341..1727122 Haemophilus influenzae 86-028NP 3431146 YP_249308.1 CDS NTHI1890 NC_007146.2 1727132 1728142 D Similar to: VPQ_BPP2; portal vertex protein 1727132..1728142 Haemophilus influenzae 86-028NP 3431147 YP_249309.1 CDS siaB NC_007146.2 1728850 1729524 R CMP-N-acetylneuraminic acid synthetase; CMP-NeuNAc synthetase; CMP-sialic acid synthetase; Similar to: HI1279, NEUA_HAEIN; acylneuraminate cytidylyltransferase complement(1728850..1729524) Haemophilus influenzae 86-028NP 3431148 YP_249310.1 CDS NTHI1892 NC_007146.2 1729638 1730300 D Similar to: HI1278, YC78_HAEIN; NAD(P)H nitroreductase 1729638..1730300 Haemophilus influenzae 86-028NP 3431149 YP_249311.2 CDS mrp NC_007146.2 1730347 1731459 R Similar to: HI1277, MRP_HAEIN; ATPase complement(1730347..1731459) Haemophilus influenzae 86-028NP 3431150 YP_249312.1 CDS metG NC_007146.2 1731610 1733658 D methionine--tRNA ligase; MetRS; methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1731610..1733658 Haemophilus influenzae 86-028NP 3431151 YP_249313.1 CDS tehB NC_007146.2 1733769 1734629 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1733769..1734629 Haemophilus influenzae 86-028NP 3431152 YP_249314.1 CDS gloB NC_007146.2 1734673 1735374 R glyoxalase II; Glx II; Similar to: HI1274, GLO2_HAEIN; hydroxyacylglutathione hydrolase complement(1734673..1735374) Haemophilus influenzae 86-028NP 3431153 YP_249315.1 CDS NTHI1897 NC_007146.2 1735426 1736232 R Similar to: HI1273, YC73_HAEIN; hypothetical protein complement(1735426..1736232) Haemophilus influenzae 86-028NP 3431154 YP_249316.1 CDS NTHI1898 NC_007146.2 1736468 1736944 D Similar to: HI1266, YC66_HAEIN; hypothetical protein 1736468..1736944 Haemophilus influenzae 86-028NP 3431155 YP_249317.1 CDS NTHI1899 NC_007146.2 1737081 1738844 D Similar to: HI1265, YCAO_HAEIN; hypothetical protein 1737081..1738844 Haemophilus influenzae 86-028NP 3431156 YP_249318.1 CDS gyrA NC_007146.2 1739444 1742086 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1739444..1742086 Haemophilus influenzae 86-028NP 3431157 YP_249319.1 CDS metX NC_007146.2 1742141 1743217 R homoserine O-trans-acetylase; homoserine transacetylase; HTA; Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase complement(1742141..1743217) Haemophilus influenzae 86-028NP 3431158 YP_249320.1 CDS sanA NC_007146.2 1743321 1744055 D Similar to: HI1262, SANA_HAEIN; SanA 1743321..1744055 Haemophilus influenzae 86-028NP 3431159 YP_249321.1 CDS folC NC_007146.2 1744343 1745656 R folylpoly-gamma-glutamate synthetase; FPGS; Similar to: HI1261, FOLC_HAEIN; folylpolyglutamate synthase complement(1744343..1745656) Haemophilus influenzae 86-028NP 3431160 YP_249322.1 CDS accD NC_007146.2 1745649 1746539 R ACCASE beta chain; catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(1745649..1746539) Haemophilus influenzae 86-028NP 3431161 YP_249323.1 CDS htoA NC_007146.2 1746733 1748124 D Similar to: HI1259, HTOA_HAEIN; periplasmic serine protease do/HhoA-like 1746733..1748124 Haemophilus influenzae 86-028NP 3431162 YP_249324.1 CDS mfd NC_007146.2 1748177 1751617 R TRCF; Similar to: HI1258, MFD_HAEIN; transcription-repair coupling factor complement(1748177..1751617) Haemophilus influenzae 86-028NP 3431163 YP_249325.1 CDS NTHI1907 NC_007146.2 1751719 1751892 R Similar to: HI1257, YC57_HAEIN; hypothetical protein complement(1751719..1751892) Haemophilus influenzae 86-028NP 3431164 YP_249326.1 CDS NTHI1908 NC_007146.2 1751889 1753859 R Similar to: HI1254, YC54_HAEIN; P-loop ATPase fused to an acetyltransferase complement(1751889..1753859) Haemophilus influenzae 86-028NP 3431165 YP_249327.1 CDS NTHI1910 NC_007146.2 1753864 1754205 R Similar to: HI1253, YC53_HAEIN; hypothetical protein complement(1753864..1754205) Haemophilus influenzae 86-028NP 3431166 YP_249328.1 CDS NTHI1911 NC_007146.2 1754267 1755937 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein complement(1754267..1755937) Haemophilus influenzae 86-028NP 3431167 YP_249329.1 CDS NTHI1912 NC_007146.2 1756100 1756423 R Similar to: HI1251, YC51_HAEIN; plasmid maintenance system antidote protein complement(1756100..1756423) Haemophilus influenzae 86-028NP 3431168 YP_249330.1 CDS NTHI1913 NC_007146.2 1756434 1756739 R Similar to: HI1250, YC50_HAEIN; plasmid maintenance system killer protein complement(1756434..1756739) Haemophilus influenzae 86-028NP 3431169 YP_249331.1 CDS NTHI1914 NC_007146.2 1757064 1757684 D Similar to: HI1249, YC49_HAEIN; ABC transporter periplasmic component 1757064..1757684 Haemophilus influenzae 86-028NP 3431170 YP_249332.1 CDS NTHI1915 NC_007146.2 1757687 1758655 D Similar to: HI1248, YC48_HAEIN; ABC transporter permease 1757687..1758655 Haemophilus influenzae 86-028NP 3431171 YP_249333.1 CDS uvrB NC_007146.2 1759269 1761308 D UvrB; excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1759269..1761308 Haemophilus influenzae 86-028NP 3431173 YP_249334.1 CDS NTHI1918 NC_007146.2 1761338 1763263 R Similar to: HI1246, YC46_HAEIN; phosphoglycerol transferase-like protein complement(1761338..1763263) Haemophilus influenzae 86-028NP 3431174 YP_249335.1 CDS mao2 NC_007146.2 1763504 1765774 R NADP-ME; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(1763504..1765774) Haemophilus influenzae 86-028NP 3431175 YP_249336.1 CDS NTHI1921 NC_007146.2 1765972 1766592 D Similar to: HI1244, YC44_HAEIN; polysaccharide biosynthesis protein 1765972..1766592 Haemophilus influenzae 86-028NP 3431176 YP_249337.1 CDS rsuA NC_007146.2 1766683 1767381 D 16S pseudouridylate 516 synthase; 16S pseudouridine 516 synthase; Uracil hydrolyase; Similar to: HI1243, RSUA_HAEIN; ribosomal small subunit pseudouridine synthase A 1766683..1767381 Haemophilus influenzae 86-028NP 3431177 YP_249338.1 CDS bcr NC_007146.2 1767383 1768579 D Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system 1767383..1768579 Haemophilus influenzae 86-028NP 3431178 YP_249339.1 CDS NTHI1924 NC_007146.2 1768611 1769411 R Similar to: HI1241, YC41_HAEIN; hypothetical protein complement(1768611..1769411) Haemophilus influenzae 86-028NP 3431179 YP_249340.1 CDS NTHI1925 NC_007146.2 1769509 1770171 D Similar to: HI1240, YICG_HAEIN; hypothetical protein 1769509..1770171 Haemophilus influenzae 86-028NP 3431180 YP_249341.1 CDS proA NC_007146.2 1770192 1771445 D GPR; glutamate-5-semialdehyde dehydrogenase; glutamyl-gamma-semialdehyde dehydrogenase; GSA dehydrogenase; Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1770192..1771445 Haemophilus influenzae 86-028NP 3431181 YP_249342.1 CDS dnaJ NC_007146.2 1771524 1772669 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ complement(1771524..1772669) Haemophilus influenzae 86-028NP 3431182 YP_249343.1 CDS dnaK NC_007146.2 1772756 1774663 R Heat shock protein 70; Heat shock 70 kDa protein; HSP70; heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(1772756..1774663) Haemophilus influenzae 86-028NP 3431183 YP_249344.1 CDS NTHI1930 NC_007146.2 1774930 1776372 D Similar to: HI1236, YC36_HAEIN; hypothetical protein 1774930..1776372 Haemophilus influenzae 86-028NP 3431184 YP_249345.1 CDS mgsA NC_007146.2 1776529 1776987 R MGS; catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(1776529..1776987) Haemophilus influenzae 86-028NP 3431185 YP_249346.1 CDS aceE NC_007146.2 1777287 1779947 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 1777287..1779947 Haemophilus influenzae 86-028NP 3431186 YP_249347.1 CDS aceF NC_007146.2 1780010 1781707 D E2; Similar to: HI1232, ODP2_HAEIN; dihydrolipoamide acetyltransferase 1780010..1781707 Haemophilus influenzae 86-028NP 3431187 YP_249348.1 CDS lpdA NC_007146.2 1781821 1783245 D E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes; E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1781821..1783245 Haemophilus influenzae 86-028NP 3431188 YP_249349.1 CDS NTHI1936 NC_007146.2 1783292 1783399 R hypothetical protein complement(1783292..1783399) Haemophilus influenzae 86-028NP 3431189 YP_249350.1 CDS apt NC_007146.2 1783405 1783947 D APRT; catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1783405..1783947 Haemophilus influenzae 86-028NP 3431190 YP_249351.1 CDS dnaX NC_007146.2 1783959 1786025 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1783959..1786025 Haemophilus influenzae 86-028NP 3431191 YP_249352.1 CDS upp NC_007146.2 1786165 1786791 D UMP pyrophosphorylase; UPRTase; Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 1786165..1786791 Haemophilus influenzae 86-028NP 3431192 YP_249353.1 CDS uraA NC_007146.2 1786895 1788139 D Uracil transporter; Similar to: HI1227, URAA_HAEIN; uracil permease 1786895..1788139 Haemophilus influenzae 86-028NP 3431193 YP_249354.1 CDS NTHI1942 NC_007146.2 1788205 1788900 D controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 1788205..1788900 Haemophilus influenzae 86-028NP 3431194 YP_249355.1 CDS NTHI1943 NC_007146.2 1788967 1789248 R Similar to: HI1225, YCIH_HAEIN; translation initiation factor 1-like proterin complement(1788967..1789248) Haemophilus influenzae 86-028NP 3431195 YP_249356.1 CDS pyrF NC_007146.2 1789255 1789947 R OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase complement(1789255..1789947) Haemophilus influenzae 86-028NP 3431196 YP_249357.1 CDS NTHI1945 NC_007146.2 1789971 1791161 R Similar to: HI1223, YCIM_HAEIN; tetratricopeptide repeat protein complement(1789971..1791161) Haemophilus influenzae 86-028NP 3431197 YP_249358.1 CDS NTHI1946 NC_007146.2 1791161 1791454 R Similar to: HI1222, YCIS_HAEIN; hypothetical protein complement(1791161..1791454) Haemophilus influenzae 86-028NP 3431198 YP_249359.1 CDS ihfB NC_007146.2 1791529 1791813 R IHF-beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta complement(1791529..1791813) Haemophilus influenzae 86-028NP 3431199 YP_249360.1 CDS rpsA NC_007146.2 1791936 1793585 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(1791936..1793585) Haemophilus influenzae 86-028NP 3431200 YP_249361.1 CDS cmk NC_007146.2 1793688 1794482 R CK; cytidine monophosphate kinase; CMP kinase; Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(1793688..1794482) Haemophilus influenzae 86-028NP 3431201 YP_249362.1 CDS NTHI1950 NC_007146.2 1794828 1795703 D with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 1794828..1795703 Haemophilus influenzae 86-028NP 3431202 YP_249363.1 CDS NTHI1951 NC_007146.2 1795704 1796282 D with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 1795704..1796282 Haemophilus influenzae 86-028NP 3431203 YP_249364.1 CDS dld NC_007146.2 1796831 1798525 R component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase complement(1796831..1798525) Haemophilus influenzae 86-028NP 3431204 YP_249365.1 CDS NTHI1953 NC_007146.2 1798785 1798895 D Similar to: HI1650; hypothetical protein 1798785..1798895 Haemophilus influenzae 86-028NP 3431205 YP_249366.1 CDS nlpC NC_007146.2 1799430 1799981 R Similar to: HI1652, NLPC_HAEIN; lipoprotein NlpC complement(1799430..1799981) Haemophilus influenzae 86-028NP 3431206 YP_249367.1 CDS tldD NC_007146.2 1800094 1801542 R Similar to: TLDD_HAEIN; hypothetical protein complement(1800094..1801542) Haemophilus influenzae 86-028NP 3431207 YP_249368.1 CDS NTHI1956 NC_007146.2 1801644 1802495 R Similar to: HI1654, YRAL_HAEIN; methyltransferase complement(1801644..1802495) Haemophilus influenzae 86-028NP 3431208 YP_249369.1 CDS NTHI1957 NC_007146.2 1802567 1804294 D Similar to: HI1655, YRAM_HAEIN; lipoprotein 1802567..1804294 Haemophilus influenzae 86-028NP 3431209 YP_249370.1 CDS NTHI1958 NC_007146.2 1804294 1804653 D Similar to: HI1656, YG56_HAEIN; hypothetical protein 1804294..1804653 Haemophilus influenzae 86-028NP 3431210 YP_249371.1 CDS NTHI1959 NC_007146.2 1804666 1805250 D Similar to: HI1657, YRAO_HAEIN; hypothetical protein 1804666..1805250 Haemophilus influenzae 86-028NP 3431211 YP_249372.1 CDS NTHI1960 NC_007146.2 1805307 1805888 D Similar to: HI1658, YRAP_HAEIN; hypothetical protein 1805307..1805888 Haemophilus influenzae 86-028NP 3431212 YP_249373.1 CDS nrdA NC_007146.2 1806143 1808413 D ribonucleotide reductase; Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1806143..1808413 Haemophilus influenzae 86-028NP 3431213 YP_249374.1 CDS nrdB NC_007146.2 1808555 1809685 D ribonucleotide reductase small subunit; B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 1808555..1809685 Haemophilus influenzae 86-028NP 3431214 YP_249375.1 CDS sucB NC_007146.2 1809801 1811030 R E2; Similar to: HI1661, ODO2_HAEIN; dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex complement(1809801..1811030) Haemophilus influenzae 86-028NP 3431215 YP_249376.1 CDS sucA NC_007146.2 1811133 1813985 R alpha-ketoglutarate dehydrogenase; SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 complement(1811133..1813985) Haemophilus influenzae 86-028NP 3431216 YP_249377.1 CDS NTHI1965 NC_007146.2 1814143 1814781 R Similar to: HI1663, YCBL_HAEIN; Zn-dependent hydrolase complement(1814143..1814781) Haemophilus influenzae 86-028NP 3431217 YP_249378.1 CDS NTHI1966 NC_007146.2 1814791 1815546 R Similar to: HI1664, YG64_HAEIN; deoxyribonuclease complement(1814791..1815546) Haemophilus influenzae 86-028NP 3431218 YP_249379.1 CDS NTHI1967 NC_007146.2 1815598 1816158 R Similar to: HI1666, YCBK_HAEIN; hypothetical protein complement(1815598..1816158) Haemophilus influenzae 86-028NP 3431219 YP_249380.1 CDS NTHI1968 NC_007146.2 1816174 1817643 R Similar to: HI1667, YCBB_HAEIN; hypothetical protein complement(1816174..1817643) Haemophilus influenzae 86-028NP 3431220 YP_249381.1 CDS prc NC_007146.2 1817717 1819804 R protease Re; C-terminal processing peptidase; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(1817717..1819804) Haemophilus influenzae 86-028NP 3431221 YP_249382.1 CDS proQ NC_007146.2 1819826 1820464 R affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector complement(1819826..1820464) Haemophilus influenzae 86-028NP 3431222 YP_249383.1 CDS NTHI1972 NC_007146.2 1820649 1821899 D Similar to: HI1671, YEBS_HAEIN; paraquat-inducible protein A-like protein 1820649..1821899 Haemophilus influenzae 86-028NP 3431223 YP_249384.1 CDS NTHI1973 NC_007146.2 1821883 1824528 D Similar to: HI1672, YEBT_HAEIN; paraquat-inducible protein B-like protein 1821883..1824528 Haemophilus influenzae 86-028NP 3431224 YP_249385.1 CDS moaE NC_007146.2 1824583 1825035 R MPT synthase subunit 2; molybdopterin synthase subunit 2; molybdenum cofactor biosynthesis protein E; molybdopterin converting factor large subunit; Similar to: HI1673, MOAE_HAEIN; molybdopterin converting factor subunit 2 complement(1824583..1825035) Haemophilus influenzae 86-028NP 3431225 YP_249386.1 CDS moaD NC_007146.2 1825036 1825281 R MPT synthase subunit 1; molybdopterin synthase subunit 1; molybdenum cofactor biosynthesis protein D; molybdopterin converting factor small subunit; catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit complement(1825036..1825281) Haemophilus influenzae 86-028NP 3431226 YP_249387.1 CDS moaC NC_007146.2 1825283 1825765 R MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC complement(1825283..1825765) Haemophilus influenzae 86-028NP 3431227 YP_249388.1 CDS moaA NC_007146.2 1825857 1826870 R together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A complement(1825857..1826870) Haemophilus influenzae 86-028NP 3431228 YP_249389.1 CDS NTHI1979 NC_007146.2 1827315 1827788 D Similar to: HI1677, YTFE_HAEIN; regulator of cell morphogenesis and NO signaling 1827315..1827788 Haemophilus influenzae 86-028NP 3431229 YP_249390.1 CDS NTHI1980 NC_007146.2 1827788 1827985 D Similar to: HI1677, YTFE_HAEIN; regulator of cell morphogenesis and NO signaling 1827788..1827985 Haemophilus influenzae 86-028NP 3431230 YP_249391.1 CDS NTHI1981 NC_007146.2 1828522 1829535 D Similar to: HI1678, YG78_HAEIN; arabinose-5-phosphate isomerase 1828522..1829535 Haemophilus influenzae 86-028NP 3431231 YP_249392.1 CDS yrbI NC_007146.2 1829545 1830087 D KDO 8-P phosphatase; Similar to: HI1679, KDOP_HAEIN; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 1829545..1830087 Haemophilus influenzae 86-028NP 3431232 YP_249393.1 CDS hmw1A NC_007146.2 1830518 1834996 D HMW1A, high molecular weight adhesin 1 1830518..1834996 Haemophilus influenzae 86-028NP 3431233 YP_249394.1 CDS hmw1B NC_007146.2 1835147 1836784 D HMW1B, OMP-85-like protein required for secretion of HMW1A and HMW2A 1835147..1836784 Haemophilus influenzae 86-028NP 3431234 YP_249395.1 CDS hmw1C NC_007146.2 1836978 1838930 D HMW1C, glycosyltransferase involved in glycosylation of HMW1A and HMW2A 1836978..1838930 Haemophilus influenzae 86-028NP 3431235 YP_249396.1 CDS NTHI1986 NC_007146.2 1839007 1841163 R Similar to: HI1680, YCCS_HAEIN; hypothetical protein complement(1839007..1841163) Haemophilus influenzae 86-028NP 3431236 YP_249397.1 CDS NTHI1987 NC_007146.2 1841231 1841896 R Similar to: HI1681, YG81_HAEIN; hypothetical protein complement(1841231..1841896) Haemophilus influenzae 86-028NP 3431237 YP_249398.1 CDS sohB NC_007146.2 1842094 1843155 D SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1842094..1843155 Haemophilus influenzae 86-028NP 3431238 YP_249399.1 CDS rnfA NC_007146.2 1843439 1844017 D Similar to: HI1683, RNFA_HAEIN; Na(+)-translocating NADH-quinone reductase subunit E 1843439..1844017 Haemophilus influenzae 86-028NP 3431239 YP_249400.1 CDS rnfB NC_007146.2 1844105 1844686 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1844105..1844686 Haemophilus influenzae 86-028NP 3431240 YP_249401.1 CDS rnfC NC_007146.2 1844687 1846684 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1844687..1846684 Haemophilus influenzae 86-028NP 3431241 YP_249402.1 CDS rnfD NC_007146.2 1846814 1847890 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1846814..1847890 Haemophilus influenzae 86-028NP 3431242 YP_249403.1 CDS rnfG NC_007146.2 1847890 1848513 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1847890..1848513 Haemophilus influenzae 86-028NP 3431243 YP_249404.1 CDS NTHI1995 NC_007146.2 1848515 1849222 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 1848515..1849222 Haemophilus influenzae 86-028NP 3431244 YP_249405.1 CDS nth NC_007146.2 1849344 1849979 D DNA-(apurinic or apyrimidinic site) lyase; Similar to: HI1689, END3_HAEIN; endonuclease III 1849344..1849979 Haemophilus influenzae 86-028NP 3431245 YP_249406.1 CDS NTHI1997 NC_007146.2 1850038 1851411 D Similar to: HI1690, YG90_HAEIN; SNF family Na+-dependent transporter 1850038..1851411 Haemophilus influenzae 86-028NP 3431246 YP_249407.1 CDS modC NC_007146.2 1851435 1852490 R Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein complement(1851435..1852490) Haemophilus influenzae 86-028NP 3431247 YP_249408.1 CDS modB NC_007146.2 1852477 1853166 R part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease protein complement(1852477..1853166) Haemophilus influenzae 86-028NP 3431248 YP_249409.1 CDS modA NC_007146.2 1853340 1854104 R Similar to: HI1693, MODA_HAEIN; molybdate-binding periplasmic protein complement(1853340..1854104) Haemophilus influenzae 86-028NP 3431249 YP_249410.1 CDS modE NC_007146.2 1854242 1855009 D Similar to: HI1694, MODE_HAEIN; transcriptional regulator ModE 1854242..1855009 Haemophilus influenzae 86-028NP 3431250 YP_249411.1 CDS lsgF NC_007146.2 1855119 1855922 R Similar to: HI1695, YG95_HAEIN; UDP-galactose--lipooligosaccharide galactosyltransferase complement(1855119..1855922) Haemophilus influenzae 86-028NP 3431251 YP_249412.1 CDS lsgE NC_007146.2 1855924 1856808 R Similar to: HI1696, YG96_HAEIN; UDP-galactose--lipooligosaccharide galactosyltransferase complement(1855924..1856808) Haemophilus influenzae 86-028NP 3431252 YP_249413.1 CDS lsgD NC_007146.2 1856820 1857593 R Similar to: HI1697, LSG4_HAEIN; UDP-GlcNAc--lipooligosaccharide N-acetylglucosaminyl glycosyltransferase complement(1856820..1857593) Haemophilus influenzae 86-028NP 3431253 YP_249414.1 CDS lsgC NC_007146.2 1857605 1858666 R Similar to: HI1698, YG98_HAEIN; UDP-galactose--lipooligosaccharide galactosyltransferase complement(1857605..1858666) Haemophilus influenzae 86-028NP 3431254 YP_249415.1 CDS lsgB NC_007146.2 1858668 1859582 R beta-galactoside alpha-2,3-sialyltransferase; Alpha 2,3-ST; lipooligosaccharide sialyltransferase; Similar to: HI1699, LST_HAEIN; CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase complement(1858668..1859582) Haemophilus influenzae 86-028NP 3431255 YP_249416.1 CDS lsgA NC_007146.2 1859579 1860784 R Similar to: HI1700, LSG1_HAEIN; lipooligosaccharide flippase complement(1859579..1860784) Haemophilus influenzae 86-028NP 3431256 YP_249417.1 CDS NTHI2008 NC_007146.2 1860919 1861662 D Similar to: HI1701, YH01_HAEIN; hypothetical protein 1860919..1861662 Haemophilus influenzae 86-028NP 3431257 YP_249418.1 CDS NTHI2011 NC_007146.2 1864348 1865424 R Similar to: HI1703, YJGQ_HAEIN; permease complement(1864348..1865424) Haemophilus influenzae 86-028NP 3431259 YP_249419.1 CDS NTHI2012 NC_007146.2 1865421 1866524 R Similar to: HI1704, YJGP_HAEIN; permease complement(1865421..1866524) Haemophilus influenzae 86-028NP 3431260 YP_249420.1 CDS pepA NC_007146.2 1866632 1868107 D aminopeptidase A; leucine aminopeptidase; LAP; Leucyl aminopeptidase; catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 1866632..1868107 Haemophilus influenzae 86-028NP 3431261 YP_249421.1 CDS NTHI2014 NC_007146.2 1868143 1870152 R Similar to: HI1706, YH06_HAEIN; choline-glycine betaine transporter complement(1868143..1870152) Haemophilus influenzae 86-028NP 3431262 YP_249422.1 CDS qseC NC_007146.2 1870447 1871802 R Similar to: HI1707, QSEC_HAEIN; sensor protein QseC complement(1870447..1871802) Haemophilus influenzae 86-028NP 3431263 YP_249423.1 CDS qseB NC_007146.2 1871799 1872464 R Similar to: HI1708, QSEB_HAEIN; transcriptional regulatory protein complement(1871799..1872464) Haemophilus influenzae 86-028NP 3431264 YP_249424.1 CDS NTHI2017 NC_007146.2 1872528 1872893 R Similar to: HI1709, YGIW_HAEIN; hypothetical protein complement(1872528..1872893) Haemophilus influenzae 86-028NP 3431265 YP_249425.1 CDS crr NC_007146.2 1874398 1874898 R EIIA-Glc; glucose-permease IIA component; phosphotransferase enzyme II, A component; EIII-Glc; functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit complement(1874398..1874898) Haemophilus influenzae 86-028NP 3431267 YP_249426.1 CDS ptsI NC_007146.2 1874958 1876685 R phosphotransferase system, enzyme I; Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase complement(1874958..1876685) Haemophilus influenzae 86-028NP 3431268 YP_249427.1 CDS ptsH NC_007146.2 1876765 1877022 R histidine-containing protein; Similar to: HI1713, PTHP_HAEIN; phosphocarrier protein HPr complement(1876765..1877022) Haemophilus influenzae 86-028NP 3431269 YP_249428.1 CDS engC NC_007146.2 1877181 1878221 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(1877181..1878221) Haemophilus influenzae 86-028NP 3431270 YP_249429.1 CDS orn NC_007146.2 1878292 1878840 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1878292..1878840 Haemophilus influenzae 86-028NP 3431271 YP_249430.1 CDS wecA NC_007146.2 1879240 1880307 R Similar to: HI1716, RFE_HAEIN; undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase complement(1879240..1880307) Haemophilus influenzae 86-028NP 3431274 YP_249431.1 CDS glnD NC_007146.2 1880382 1882973 R PII uridylyl-transferase; uridylyl removing enzyme; UTase; Similar to: HI1719, GLND_HAEIN; PII uridylyl-transferase complement(1880382..1882973) Haemophilus influenzae 86-028NP 3431275 YP_249432.1 CDS map NC_007146.2 1883067 1883873 R MAP; peptidase M; catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(1883067..1883873) Haemophilus influenzae 86-028NP 3431276 YP_249433.1 CDS NTHI2029 NC_007146.2 1884009 1884353 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 1884009..1884353 Haemophilus influenzae 86-028NP 3431277 YP_249434.1 CDS NTHI2030 NC_007146.2 1884355 1884708 D Similar to: HI1724, YH24_HAEIN; hypothetical protein 1884355..1884708 Haemophilus influenzae 86-028NP 3431278 YP_249435.1 CDS mrcB NC_007146.2 1884715 1887060 D PBP-1b; PBP1b; Murein polymerase; peptidoglycan glycosyltransferase; peptidoglycan TGase; DD-transpeptidase; Similar to: HI1725, PBPB_HAEIN; penicillin-binding protein 1B 1884715..1887060 Haemophilus influenzae 86-028NP 3431279 YP_249436.1 CDS hemH NC_007146.2 1887185 1888105 D SAICAR synthetase; catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1887185..1888105 Haemophilus influenzae 86-028NP 3431280 YP_249437.1 CDS argG NC_007146.2 1888261 1889595 D citrulline--aspartate ligase; catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 1888261..1889595 Haemophilus influenzae 86-028NP 3431281 YP_249438.1 CDS NTHI2035 NC_007146.2 1889666 1890859 R Similar to: HI1728, YH28_HAEIN; manganese transporter NRAMP complement(1889666..1890859) Haemophilus influenzae 86-028NP 3431282 YP_249439.1 CDS NTHI2036 NC_007146.2 1890903 1891640 R Similar to: HI1729, YH29_HAEIN; LamB/YcsF family protein complement(1890903..1891640) Haemophilus influenzae 86-028NP 3431283 YP_249440.1 CDS NTHI2037 NC_007146.2 1891627 1892556 R Similar to: HI1730, YBGK_HAEIN; allophanate hydrolase subunit 2 complement(1891627..1892556) Haemophilus influenzae 86-028NP 3431284 YP_249441.1 CDS NTHI2038 NC_007146.2 1892553 1893194 R Similar to: HI1731, YBGJ_HAEIN; allophanate hydrolase subunit 1 complement(1892553..1893194) Haemophilus influenzae 86-028NP 3431285 YP_249442.1 CDS rnb NC_007146.2 1893456 1895435 R ribonuclease II; RNase II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1893456..1895435) Haemophilus influenzae 86-028NP 3431286 YP_249443.1 CDS fabI NC_007146.2 1895533 1896420 R NADH-dependent enoyl-ACP reductase; Similar to: HI1734, FABI_HAEIN; enoyl-ACP reductase complement(1895533..1896420) Haemophilus influenzae 86-028NP 3431287 YP_249444.1 CDS prfC NC_007146.2 1896500 1898083 D RF-3; stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 1896500..1898083 Haemophilus influenzae 86-028NP 3431288 YP_249445.1 CDS NTHI2045 NC_007146.2 1898159 1898392 R Similar to: HI1736, YH36_HAEIN; hypothetical protein complement(1898159..1898392) Haemophilus influenzae 86-028NP 3431289 YP_249446.1 CDS NTHI2046 NC_007146.2 1898495 1898824 R Similar to: HI1737, YH37_HAEIN; branched-chain amino acid permease complement(1898495..1898824) Haemophilus influenzae 86-028NP 3431290 YP_249447.1 CDS NTHI2047 NC_007146.2 1898821 1899555 R Similar to: HI1738, YH38_HAEIN; branched-chain amino acid permease complement(1898821..1899555) Haemophilus influenzae 86-028NP 3431291 YP_249448.1 CDS metR NC_007146.2 1899565 1900494 R Similar to: HI1739, METR_HAEIN; HTH-type transcriptional regulator MetR complement(1899565..1900494) Haemophilus influenzae 86-028NP 3431292 YP_249449.1 CDS lldD NC_007146.2 1906825 1907970 R flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase complement(1906825..1907970) Haemophilus influenzae 86-028NP 3431298 YP_249450.1 CDS murI NC_007146.2 1908182 1908991 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(1908182..1908991) Haemophilus influenzae 86-028NP 3431299 YP_249451.1 CDS recG NC_007146.2 1909021 1911102 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(1909021..1911102) Haemophilus influenzae 86-028NP 3431300 YP_249452.1 CDS spoT NC_007146.2 1911099 1913213 R diphosphate; (ppGpp)ase; Penta-phosphate guanosine-3'-pyrophosphohydrolase; Similar to: HI1741, SPOT_HAEIN; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase complement(1911099..1913213) Haemophilus influenzae 86-028NP 3431301 YP_249453.1 CDS rpoZ NC_007146.2 1913286 1913552 R transcriptase omega chain; RNA polymerase omega subunit; promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(1913286..1913552) Haemophilus influenzae 86-028NP 3431302 YP_249454.1 CDS gmk NC_007146.2 1913615 1914241 R GMP kinase; Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(1913615..1914241) Haemophilus influenzae 86-028NP 3431303 NTHIT0001 tRNA NTHIT0001 NC_007146.2 47130 47219 D tRNA-Ser 47130..47219 Haemophilus influenzae 86-028NP 3431052 NTHIT0002 tRNA NTHIT0002 NC_007146.2 91989 92064 D tRNA-Gly 91989..92064 Haemophilus influenzae 86-028NP 3429437 NTHIT0003 tRNA NTHIT0003 NC_007146.2 92071 92144 D tRNA-Cys 92071..92144 Haemophilus influenzae 86-028NP 3429438 NTHIT0004 tRNA NTHIT0004 NC_007146.2 92172 92258 D tRNA-Leu 92172..92258 Haemophilus influenzae 86-028NP 3429439 NTHIT0005 tRNA NTHIT0005 NC_007146.2 148717 148792 D tRNA-Lys 148717..148792 Haemophilus influenzae 86-028NP 3429501 NTHIT0006 tRNA NTHIT0006 NC_007146.2 193008 193083 R tRNA-Glu complement(193008..193083) Haemophilus influenzae 86-028NP 3429536 NTHIT0007 tRNA NTHIT0007 NC_007146.2 194933 195009 R tRNA-Pro complement(194933..195009) Haemophilus influenzae 86-028NP 3429538 NTHIT0008 tRNA NTHIT0008 NC_007146.2 195031 195106 R tRNA-His complement(195031..195106) Haemophilus influenzae 86-028NP 3429539 NTHIT0009 tRNA NTHIT0009 NC_007146.2 195133 195209 R tRNA-Arg complement(195133..195209) Haemophilus influenzae 86-028NP 3429540 NTHIT0010 tRNA NTHIT0010 NC_007146.2 197626 197702 R tRNA-Met complement(197626..197702) Haemophilus influenzae 86-028NP 3429542 NTHIT0011 tRNA NTHIT0011 NC_007146.2 206099 206174 D tRNA-Gly 206099..206174 Haemophilus influenzae 86-028NP 3429551 NTHIT0012 tRNA NTHIT0012 NC_007146.2 206179 206265 D tRNA-Leu 206179..206265 Haemophilus influenzae 86-028NP 3429552 NTHIT0013 tRNA NTHIT0013 NC_007146.2 206316 206391 D tRNA-Lys 206316..206391 Haemophilus influenzae 86-028NP 3429553 NTHIT0014 tRNA NTHIT0014 NC_007146.2 214427 214503 R tRNA-Asp complement(214427..214503) Haemophilus influenzae 86-028NP 3429561 NTHIT0015 tRNA NTHIT0015 NC_007146.2 214527 214603 R tRNA-Asp complement(214527..214603) Haemophilus influenzae 86-028NP 3429562 NTHIT0016 tRNA NTHIT0016 NC_007146.2 309531 309606 R tRNA-Glu complement(309531..309606) Haemophilus influenzae 86-028NP 3429651 NTHIT0017 tRNA NTHIT0017 NC_007146.2 351204 351293 R tRNA-Ser complement(351204..351293) Haemophilus influenzae 86-028NP 3429689 NTHIT0018 tRNA NTHIT0018 NC_007146.2 369751 369826 R tRNA-Ala complement(369751..369826) Haemophilus influenzae 86-028NP 3429706 NTHIT0019 tRNA NTHIT0019 NC_007146.2 371520 371595 D tRNA-Val 371520..371595 Haemophilus influenzae 86-028NP 3429708 NTHIT0020 tRNA NTHIT0020 NC_007146.2 371639 371714 D tRNA-Val 371639..371714 Haemophilus influenzae 86-028NP 3429709 NTHIT0021 tRNA NTHIT0021 NC_007146.2 371773 371848 D tRNA-Val 371773..371848 Haemophilus influenzae 86-028NP 3429710 NTHIT0022 tRNA NTHIT0022 NC_007146.2 371901 371976 D tRNA-Val 371901..371976 Haemophilus influenzae 86-028NP 3429711 NTHIT0023 tRNA NTHIT0023 NC_007146.2 423749 423838 R tRNA-Ser complement(423749..423838) Haemophilus influenzae 86-028NP 3429766 NTHIT0024 tRNA NTHIT0024 NC_007146.2 470638 470713 R tRNA-Lys complement(470638..470713) Haemophilus influenzae 86-028NP 3429818 NTHIT0025 tRNA NTHIT0025 NC_007146.2 470737 470812 R tRNA-Lys complement(470737..470812) Haemophilus influenzae 86-028NP 3429819 NTHIT0026 tRNA NTHIT0026 NC_007146.2 534455 534540 D tRNA-Leu 534455..534540 Haemophilus influenzae 86-028NP 3429884 NTHIT0027 tRNA NTHIT0027 NC_007146.2 668564 668639 R tRNA-Thr complement(668564..668639) Haemophilus influenzae 86-028NP 3430020 NTHIT0028 tRNA NTHIT0028 NC_007146.2 668643 668717 R tRNA-Gly complement(668643..668717) Haemophilus influenzae 86-028NP 3430021 NTHIT0029 tRNA NTHIT0029 NC_007146.2 668760 668844 R tRNA-Tyr complement(668760..668844) Haemophilus influenzae 86-028NP 3430022 NTHIT0030 tRNA NTHIT0030 NC_007146.2 668874 668949 R tRNA-Thr complement(668874..668949) Haemophilus influenzae 86-028NP 3430023 NTHIT0031 tRNA NTHIT0031 NC_007146.2 682515 682590 R tRNA-Ala complement(682515..682590) Haemophilus influenzae 86-028NP 3430038 NTHIT0032 tRNA NTHIT0032 NC_007146.2 682676 682752 R tRNA-Ile complement(682676..682752) Haemophilus influenzae 86-028NP 3430039 NTHIT0033 tRNA NTHIT0033 NC_007146.2 719385 719461 R tRNA-Arg complement(719385..719461) Haemophilus influenzae 86-028NP 3430072 NTHIT0034 tRNA NTHIT0034 NC_007146.2 719519 719595 R tRNA-Arg complement(719519..719595) Haemophilus influenzae 86-028NP 3430073 NTHIT0035 tRNA NTHIT0035 NC_007146.2 719616 719709 R tRNA-Ser complement(719616..719709) Haemophilus influenzae 86-028NP 3430074 NTHIT0036 tRNA NTHIT0036 NC_007146.2 787682 787772 R tRNA-Sec complement(787682..787772) Haemophilus influenzae 86-028NP 3430139 NTHIT0037 tRNA NTHIT0037 NC_007146.2 807475 807550 D tRNA-Glu 807475..807550 Haemophilus influenzae 86-028NP 3430158 NTHIT0038 tRNA NTHIT0038 NC_007146.2 811470 811546 D tRNA-Asp 811470..811546 Haemophilus influenzae 86-028NP 3430162 NTHIT0039 tRNA NTHIT0039 NC_007146.2 811575 811650 D tRNA-Trp 811575..811650 Haemophilus influenzae 86-028NP 3430163 NTHIT0040 tRNA NTHIT0040 NC_007146.2 823125 823201 D tRNA-Pro 823125..823201 Haemophilus influenzae 86-028NP 3430173 NTHIT0041 tRNA NTHIT0041 NC_007146.2 823249 823325 D tRNA-Arg 823249..823325 Haemophilus influenzae 86-028NP 3430174 NTHIT0042 tRNA NTHIT0042 NC_007146.2 840747 840823 D tRNA-Ile 840747..840823 Haemophilus influenzae 86-028NP 3430190 NTHIT0043 tRNA NTHIT0043 NC_007146.2 840909 840984 D tRNA-Ala 840909..840984 Haemophilus influenzae 86-028NP 3430191 NTHIT0044 tRNA NTHIT0044 NC_007146.2 890703 890778 D tRNA-Phe 890703..890778 Haemophilus influenzae 86-028NP 3430230 NTHIT0045 tRNA NTHIT0045 NC_007146.2 890781 890856 D tRNA-Asn 890781..890856 Haemophilus influenzae 86-028NP 3430231 NTHIT0046 tRNA NTHIT0046 NC_007146.2 1040736 1040812 R tRNA-Met complement(1040736..1040812) Haemophilus influenzae 86-028NP 3430386 NTHIT0047 tRNA NTHIT0047 NC_007146.2 1339908 1339984 D tRNA-Met 1339908..1339984 Haemophilus influenzae 86-028NP 3430660 NTHIT0048 tRNA NTHIT0048 NC_007146.2 1339990 1340074 D tRNA-Leu 1339990..1340074 Haemophilus influenzae 86-028NP 3430661 NTHIT0049 tRNA NTHIT0049 NC_007146.2 1340103 1340177 D tRNA-Gln 1340103..1340177 Haemophilus influenzae 86-028NP 3430662 NTHIT0050 tRNA NTHIT0050 NC_007146.2 1340225 1340299 D tRNA-Gln 1340225..1340299 Haemophilus influenzae 86-028NP 3430663 NTHIT0051 tRNA NTHIT0051 NC_007146.2 1408188 1408264 D tRNA-Val 1408188..1408264 Haemophilus influenzae 86-028NP 3430728 NTHIT0052 tRNA NTHIT0052 NC_007146.2 1576016 1576101 D tRNA-Leu 1576016..1576101 Haemophilus influenzae 86-028NP 3430937 NTHIT0053 tRNA NTHIT0053 NC_007146.2 1702152 1702228 R tRNA-Met complement(1702152..1702228) Haemophilus influenzae 86-028NP 3431111 NTHIT0054 tRNA NTHIT0054 NC_007146.2 1758758 1758833 R tRNA-Asn complement(1758758..1758833) Haemophilus influenzae 86-028NP 3431172 NTHIT0055 tRNA NTHIT0055 NC_007146.2 1878934 1879009 D tRNA-Gly 1878934..1879009 Haemophilus influenzae 86-028NP 3431272 NTHIT0056 tRNA NTHIT0056 NC_007146.2 1879034 1879109 D tRNA-Gly 1879034..1879109 Haemophilus influenzae 86-028NP 3431273 NTHIT0057 tRNA NTHIT0057 NC_007146.2 1904602 1904677 R tRNA-Ala complement(1904602..1904677) Haemophilus influenzae 86-028NP 3431295 NTHIT0058 tRNA NTHIT0058 NC_007146.2 1904763 1904839 R tRNA-Ile complement(1904763..1904839) Haemophilus influenzae 86-028NP 3431296 NTHIR0001 rRNA NTHIR0001 NC_007146.2 189266 189380 R 5S ribosomal RNA complement(189266..189380) Haemophilus influenzae 86-028NP 3429534 NTHIR0002 rRNA NTHIR0002 NC_007146.2 189626 192737 R 23S ribosomal RNA complement(189626..192737) Haemophilus influenzae 86-028NP 3429535 NTHIR0003 rRNA NTHIR0003 NC_007146.2 193215 194753 R 16S ribosomal RNA complement(193215..194753) Haemophilus influenzae 86-028NP 3429537 NTHIR0004 rRNA NTHIR0004 NC_007146.2 305789 305903 R 5S ribosomal RNA complement(305789..305903) Haemophilus influenzae 86-028NP 3429649 NTHIR0005 rRNA NTHIR0005 NC_007146.2 306149 309260 R 23S ribosomal RNA complement(306149..309260) Haemophilus influenzae 86-028NP 3429650 NTHIR0006 rRNA NTHIR0006 NC_007146.2 309738 311276 R 16S ribosomal RNA complement(309738..311276) Haemophilus influenzae 86-028NP 3429652 NTHIR0007 rRNA NTHIR0007 NC_007146.2 678644 678758 R 5S ribosomal RNA complement(678644..678758) Haemophilus influenzae 86-028NP 3430036 NTHIR0008 rRNA NTHIR0008 NC_007146.2 679004 682114 R 23S ribosomal RNA complement(679004..682114) Haemophilus influenzae 86-028NP 3430037 NTHIR0009 rRNA NTHIR0009 NC_007146.2 682832 684370 R 16S ribosomal RNA complement(682832..684370) Haemophilus influenzae 86-028NP 3430040 NTHIR0010 rRNA NTHIR0010 NC_007146.2 805805 807343 D 16S ribosomal RNA 805805..807343 Haemophilus influenzae 86-028NP 3430157 NTHIR0011 rRNA NTHIR0011 NC_007146.2 807821 810932 D 23S ribosomal RNA 807821..810932 Haemophilus influenzae 86-028NP 3430159 NTHIR0012 rRNA NTHIR0012 NC_007146.2 811178 811292 D 5S ribosomal RNA 811178..811292 Haemophilus influenzae 86-028NP 3430160 NTHIR0013 rRNA NTHIR0013 NC_007146.2 811342 811454 D 5S ribosomal RNA 811342..811454 Haemophilus influenzae 86-028NP 3430161 NTHIR0014 rRNA NTHIR0014 NC_007146.2 839129 840667 D 16S ribosomal RNA 839129..840667 Haemophilus influenzae 86-028NP 3430189 NTHIR0015 rRNA NTHIR0015 NC_007146.2 841391 844502 D 23S ribosomal RNA 841391..844502 Haemophilus influenzae 86-028NP 3430192 NTHIR0016 rRNA NTHIR0016 NC_007146.2 844749 844863 D 5S ribosomal RNA 844749..844863 Haemophilus influenzae 86-028NP 3430193 NTHIR0017 rRNA NTHIR0017 NC_007146.2 1900731 1900845 R 5S ribosomal RNA complement(1900731..1900845) Haemophilus influenzae 86-028NP 3431293 NTHIR0018 rRNA NTHIR0018 NC_007146.2 1901091 1904202 R 23S ribosomal RNA complement(1901091..1904202) Haemophilus influenzae 86-028NP 3431294 NTHIR0019 rRNA NTHIR0019 NC_007146.2 1904919 1906457 R 16S ribosomal RNA complement(1904919..1906457) Haemophilus influenzae 86-028NP 3431297