-- dump date   	20140619_104831
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
NP_438174.1	catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate
NP_438175.1	similar to GB:AE000782
NP_438176.1	similar to GB:L10328 SP:P09997 PID:290545 PID:41648 GB:U00096
NP_438177.1	similar to GB:U00096 SP:P77385 PID:1778578 PID:1786880
NP_438178.1	involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth
NP_438180.1	similar to SP:P24184 GB:U00096 PID:1742408 PID:1742418 PID:1787749
NP_438181.1	similar to GB:L19201 SP:P32174 PID:304996 GB:U00096 PID:1790325
NP_438182.1	required for the formation of active formate dehydrogenase
NP_438183.1	alanine acetyltransferase that specifically acetylates ribosomal protein S18
NP_438184.1	with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB
NP_438185.1	16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit
NP_438186.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
NP_438187.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
NP_438188.1	similar to GB:K00426 SP:P00803 PID:146600 PID:987643 GB:U00096
NP_438189.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
NP_438190.1	stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit
NP_438191.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NP_438192.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
NP_438193.1	similar to GB:U00096 SP:P75763 PID:1786986
NP_438194.1	similar to GB:U00096 SP:P77231 PID:1778530 PID:1786830
NP_438195.1	similar to GB:U00096 SP:P75726 PID:1778532 PID:1786832
NP_438196.2	similar to GB:U00096 SP:P77770 PID:1778533 PID:1786833
NP_438197.1	acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate
NP_438198.1	similar to SP:P77390
NP_438199.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
NP_438200.1	lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein
NP_438201.1	similar to GB:L07636 SP:P30977 PID:146621 GB:U00096 PID:1778548
NP_438202.1	similar to SP:P04287 PID:146620 PID:147661 PID:41212 GB:U00096
NP_438203.1	similar to GB:M18276 SP:P10100 PID:147660 GB:U00096 PID:1651260
NP_438204.1	similar to GB:M22857 SP:P15035 PID:147695 GB:U00096 PID:1651261
NP_438205.1	similar to SP:P08150 GB:X04516 PID:147694 PID:42316 GB:U00096
NP_438206.1	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
NP_438207.1	similar to SP:P05848 GB:X04516 PID:42314 GB:U00096 PID:1778554
NP_438208.1	similar to GB:L10328 SP:P29211 GB:M94104 PID:290534 PID:147371
NP_438209.1	similar to SP:Q50614 PID:1483552
NP_438210.2	functions in MreBCD complex in some organisms
NP_438211.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
NP_438212.1	similar to GB:M31792 SP:P16927 PID:146819 PID:606189 GB:U00096
NP_438213.1	similar to PID:1944176
NP_438214.1	removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction
NP_438215.1	similar to SP:P39219 GB:U00096 PID:1786244
NP_438216.1	similar to SP:P45525 GB:U00096 PID:1787582
NP_438217.1	similar to SP:P06967 GB:X00547 PID:41284 GB:U00096 PID:1787205
NP_438218.1	similar to GB:U14003 SP:P39187 PID:471102 PID:537057 GB:U00096
NP_438219.2	similar to SP:P16680 GB:U14003 PID:147194 PID:536952 GB:U00096
NP_438220.1	catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate
NP_438221.1	Converts D-mannonate to D-mannuronate
NP_438222.1	similar to GB:X75047 SP:P45416 PID:495249
NP_438224.1	similar to SP:P37674 PID:466715 GB:U00096 PID:1790002
NP_438225.1	similar to SP:P37676 PID:466717 GB:U00096 PID:1790004
NP_438226.1	similar to GB:M96947 SP:Q06004 PID:304153 GB:AL009126
NP_438227.2	similar to GB:U14003 SP:P39161 PID:537165 PID:1160324 GB:U00096
NP_438228.1	catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate
NP_438229.1	similar to PID:882725 GB:U00096 PID:1789197
NP_438230.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NP_438231.1	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS
NP_438232.1	transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate
NP_438233.1	involved in the transport of lipid A across the inner membrane
NP_438234.1	similar to GB:L20805 PID:305386
NP_438235.1	similar to GB:D26562 SP:P18274 GB:M34945 GB:M60726 PID:145751
NP_438236.1	similar to SP:P13685 GB:D26562 GB:M20574 GB:S48039 PID:147117
NP_438237.1	ATP-binding protein; similar to GB:D26562 SP:P26281 GB:L06495 PID:146013 PID:473801
NP_438238.1	forms homotrimers; magnesium-dependent; similar to SP:P31805 PID:304913 PID:537009 GB:U00096 PID:1790610
NP_438239.1	similar to SP:P26365 GB:Z11831 PID:304914 PID:42068 PID:537010
NP_438240.1	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NP_438241.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
NP_438242.1	catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme
NP_438243.1	similar to SP:P05824 GB:Y00357 PID:42693 PID:1033112 GB:U00096
NP_438244.1	catalyzes the phosphorylation of NAD to NADP
NP_438245.2	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor
NP_438246.1	forms complexes with HI0074
NP_438247.1	forms homodimers and complexes with HI0073
NP_438248.1	Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates
NP_438249.1	similar to GB:M63308 SP:P23911 PID:147932 GB:U00096 PID:1773136
NP_438251.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
NP_438252.1	similar to GB:M55430 SP:P23869 GB:X59293 PID:145290 PID:41205
NP_438253.1	similar to GB:U00096 PID:2367279
NP_438254.1	similar to GB:U14003 SP:P39408 PID:537218 GB:U00096 PID:1790838
NP_438257.1	similar to GB:J04475 SP:P12243 PID:142154
NP_438258.1	Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthes
NP_438259.1	catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity
NP_438260.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
NP_438261.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
NP_438262.1	multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways
NP_438263.1	similar to PID:882480 SP:P52054 GB:U00096 PID:1789321
NP_438264.1	similar to SP:P42100 PID:563934 PID:904179 GB:AL009126
NP_438266.1	similar to SP:P37047 GB:U00096 PID:1552740 PID:1786357
NP_438269.1	similar to PID:2104289
NP_438271.2	periplasmic ferric iron binding protein; contains a frameshift with respect to purified protein; similar to PID:2340838
NP_438272.2	similar to GB:M33815 SP:P21409 PID:152861
NP_438273.1	similar to PID:1098689
NP_438276.1	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.
NP_438277.1	similar to SP:P24178 GB:X57403 PID:41233 GB:U00096 PID:1788815
NP_438278.1	molecular chaperone
NP_438279.2	similar to GB:U00096 SP:P75743 PID:1786928
NP_438280.1	similar to SP:P07019 PID:43142 GB:U00096 PID:1788963
NP_438281.1	similar to GB:U00096 PID:1788966
NP_438282.1	similar to GB:U14003 SP:P39402 PID:537207 GB:U00096 PID:1790826
NP_438284.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_438285.1	similar to GB:X76500 PID:520921
NP_438287.1	similar to SP:Q56989 PID:1407797
NP_438290.1	similar to GB:D21145 PID:471103 PID:882707 GB:U00096 SP:Q46927
NP_438291.1	involved in transport of zinc(II) with ZnuA and C
NP_438293.1	similar to GB:U14003 SP:P37773 PID:537075 GB:U00096 PID:1790680
NP_438294.1	catalyzes the formation of L-homocysteine from cystathionine
NP_438295.1	similar to GB:M12299 SP:P06978 PID:473749 GB:U00096 PID:1736571
NP_438296.1	catalyzes the hydrolysis of pyrophosphate to phosphate
NP_438297.1	similar to SP:P32702 PID:396399 GB:U00096 PID:1790499
NP_438298.1	Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import
NP_438300.1	AfuA; similar to PID:1469286 PID:1477455
NP_438301.1	functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor
NP_438302.1	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis
NP_438304.1	similar to GB:AE000511 PID:2314345
NP_438305.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
NP_438306.1	3'-5' exonuclease of DNA polymerase III
NP_438307.1	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
NP_438308.1	similar to GB:J03359 SP:P20149
NP_438309.1	catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate
NP_438310.1	catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate
NP_438311.1	catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid
NP_438312.1	similar to GB:M81878 SP:P26833 PID:144859
NP_438313.1	catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein
NP_438314.1	Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate
NP_438315.1	similar to SP:P37676 PID:466717 GB:U00096 PID:1790004
NP_438316.1	similar to SP:P37675 PID:466716 GB:U00096 PID:1790003
NP_438317.1	similar to GB:U14003 SP:P39371 PID:537151 GB:U00096 PID:1790764
NP_438320.1	similar to SP:P25661 GB:U00005 PID:436158 PID:537016 GB:U00096
NP_438321.1	similar to SP:P25662 GB:U00005 PID:436157 PID:537015 GB:U00096
NP_438324.1	carries the fatty acid chain in fatty acid biosynthesis
NP_438325.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NP_438326.1	similar to GB:M87040 SP:P25715 GB:Z11565 PID:145887 PID:41364
NP_438327.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
NP_438328.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
NP_438329.1	similar to GB:M29698 SP:P14189 PID:146052 PID:147711 GB:U00096
NP_438330.1	catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine
NP_438331.1	catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense
NP_438332.1	similar to GB:U00096 PID:1773118 PID:1786637
NP_438333.1	similar to PID:663269
NP_438334.1	uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
NP_438335.1	uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
NP_438336.1	uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
NP_438337.1	Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm
NP_438338.1	Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
NP_438339.1	uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
NP_438340.1	similar to SP:P33944 PID:405940 GB:U00096 PID:1788543
NP_438342.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
NP_438343.1	similar to SP:P33644 GB:M29364 PID:1236632 PID:147364 GB:U00096
NP_438344.1	responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA
NP_438345.1	similar to PID:1107833
NP_438347.1	activates pyruvate formate-lyase 1 under anaerobic conditions
NP_438348.1	similar to GB:X08035 SP:P09373 PID:42370 GB:U00096 PID:1651427
NP_438349.1	similar to SP:P21501 PID:147154 GB:U00096 PID:1651428 PID:1651435
NP_438350.2	catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine
NP_438351.1	similar to PID:757741 SP:Q45068 PID:1405464 GB:AL009126
NP_438352.1	similar to SP:P10768
NP_438353.1	similar to SP:P25437 PID:887431 GB:U00096 PID:1786552 PID:2443392
NP_438354.1	similar to GB:D26185 SP:P37510 PID:467364 GB:AL009126
NP_438356.1	mediates the export of protein precursors bearing twin-arginine signal peptides
NP_438357.1	similar to SP:P27857 GB:M87049 PID:148238 PID:148237 GB:U00096
NP_438358.1	converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer
NP_438359.1	similar to PID:1568605
NP_438360.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
NP_438361.2	similar to GB:U00096 PID:1786902
NP_438362.1	negative modulator of the initiation of chromosome replication
NP_438363.1	similar to GB:L35031 SP:P37353 PID:520813 GB:U00096 PID:1788595
NP_438364.1	small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS
NP_438365.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
NP_438366.1	D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm
NP_438367.1	similar to SP:P14008 PID:41996 GB:U00096 PID:1788667
NP_438368.1	Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA
NP_438369.1	catalyzes the formation of selenophosphate from selenide and ATP
NP_438370.2	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NP_438371.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
NP_438372.2	Essential for efficient processing of 16S rRNA
NP_438373.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
NP_438375.1	similar to SP:P29240 PID:62772
NP_438376.1	catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis
NP_438377.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
NP_438378.1	similar to GB:J01600 SP:P00475 GB:V00272 GB:Z19601 PID:145706
NP_438379.1	similar to GB:M23628 SP:P18201 PID:450384 GB:U00096 PID:1742092
NP_438380.2	catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate
NP_438381.1	similar to SP:P06202 GB:X05491 GB:X52093 PID:47802 PID:47808
NP_438383.2	similar to SP:P27298 GB:M93984 PID:451277 PID:466635 GB:U00096
NP_438384.1	similar to GB:X73984 PID:393411
NP_438385.1	similar to PID:984584 GB:U00096 SP:Q47152 PID:1552796 PID:1786422
NP_438387.2	similar to GB:S68137 SP:P46928 PID:469476
NP_438391.1	catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon
NP_438392.1	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
NP_438393.1	similar to C-terminus of HI0221
NP_438394.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
NP_438395.1	similar to SP:P27844
NP_438396.2	similar to SP:P55658 PID:2182633
NP_438397.1	exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH
NP_438398.1	similar to SP:P37011 GB:U00096 PID:1657597 PID:1773085 PID:1786601
NP_438399.1	similar to SP:P37673 PID:466714 GB:U00096 PID:1790001
NP_438401.1	similar to GB:J02638 SP:P05055 GB:M14425 GB:X00761 PID:147749
NP_438402.1	lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing
NP_438403.1	similar to SP:P23304 GB:M63288 GB:U03750 PID:432406 PID:606102
NP_438404.1	YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function
NP_438406.1	similar to GB:L29458 SP:P36675 PID:473421
NP_438407.1	similar to PID:1805555
NP_438409.1	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
NP_438410.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
NP_438411.1	member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex
NP_438412.1	similar to GB:L77117 SP:Q58397 PID:1591652
NP_438414.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
NP_438415.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
NP_438418.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NP_438419.1	binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA
NP_438420.1	similar to GB:U04996
NP_438421.1	similar to PID:555672 PID:1573218
NP_438422.1	similar to PID:555671
NP_438423.1	bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine
NP_438424.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
NP_438425.1	similar to SP:P21167 PID:147409 PID:42126 GB:U00096 PID:1788822
NP_438426.1	structural determination suggests similarity to dsRNA-binding proteins; similar to YfiA; similar to SP:P17160 GB:X05888 GB:X16334 PID:39270 PID:39276
NP_438427.1	similar to PID:1857120
NP_438428.1	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine
NP_438429.1	catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position
NP_438430.1	similar to GB:L21026 PID:311045
NP_438431.1	similar to SP:P45357 PID:595326
NP_438432.1	similar to SP:P45356 PID:1573229
NP_438433.1	similar to GB:U08348 PID:540014
NP_438434.1	similar to SP:P31055 PID:882580 GB:U00096 PID:1789438
NP_438435.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX
NP_438436.1	similar to GB:M94724 SP:P27896 GB:X65714 PID:146928 PID:581139
NP_438437.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
NP_438438.1	binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters
NP_438439.1	similar to SP:P33371 PID:405871 GB:U00096 PID:1788462
NP_438440.1	functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system
NP_438441.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
NP_438442.1	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs
NP_438443.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
NP_438445.1	RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease
NP_438446.1	similar to GB:L20251 SP:P37052 PID:410154 GB:U00096 PID:1787484
NP_438448.2	catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway
NP_438449.1	similar to SP:P37643 PID:466660 GB:U00096 PID:1789941
NP_438450.1	catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA
NP_438451.1	SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis
NP_438452.1	synthesizes isochorismate acid from chorismate
NP_438453.1	broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor
NP_438454.1	similar to GB:M58338 SP:P22306 GB:M59862 PID:146894 PID:146896
NP_438455.1	similar to GB:M28695 SP:P16095 PID:290464 GB:U00096 PID:1736451
NP_438456.1	similar to SP:P36559 GB:U01233 PID:402256 PID:882691 GB:U00096
NP_438457.1	similar to GB:AL009126
NP_438459.1	similar to GB:X73112 PID:483769 SP:Q51770
NP_438460.1	similar to GB:U00096 SP:P77565 PID:1773169 PID:1786695
NP_438461.1	when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis
NP_438462.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
NP_438463.1	similar to SP:P25960 GB:L28106 PID:145410 PID:451905 PID:606269
NP_438464.1	similar to GB:M32066 SP:P22609 PID:151066
NP_438465.1	similar to GB:M32066 SP:P22608 GB:S43866 PID:151065
NP_438466.1	similar to GB:D26562 SP:P36647 GB:L28105 PID:473777 PID:456042
NP_438467.1	similar to GB:D26562 SP:P13016 GB:L28105 GB:X15237 PID:40908
NP_438468.1	similar to GB:U00096 PID:1778577 PID:1786879
NP_438469.2	Transfers the fatty acyl group on membrane lipoproteins
NP_438470.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
NP_438471.1	similar to PID:882477 SP:P52049 GB:U00096 PID:1789317
NP_438472.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
NP_438473.1	Required for efficient pilin antigenic variation
NP_438474.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
NP_438475.1	transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters
NP_438476.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
NP_438478.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
NP_438479.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
NP_438480.1	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity
NP_438481.1	similar to GB:D10165 SP:P24237 PID:216652 PID:42173 GB:U00096
NP_438482.2	converts dATP to dAMP and pyrophosphate
NP_438483.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
NP_438484.1	similar to SP:P54158 PID:1256620 GB:AL009126
NP_438485.1	YecO; contains bound cofactor S-adenosyl-L-homocysteine; similar to GB:U00096 PID:1788177
NP_438486.1	similar to GB:L22308 GB:L31763 GB:M74565 PID:145069 PID:438535
NP_438487.1	similar to GB:L22308 GB:L31763 GB:M74565 PID:145068 PID:438534
NP_438488.1	similar to GB:U00096 SP:Q59384 PID:1354845 PID:1711245 PID:1787940
NP_438489.1	Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A)
NP_438490.1	similar to GB:AL009126
NP_438492.3	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
NP_438493.1	similar to GB:U14003 SP:P39280 PID:536990 GB:U00096 PID:1790589
NP_438494.1	similar to GB:L42023 SP:P44415 PID:1003551 PID:1222255 PID:595942
NP_438495.1	similar to GB:L42023 SP:P44416 PID:1003553 PID:1222256 PID:595943
NP_438496.1	involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA
NP_438497.1	in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]
NP_438498.1	similar to GB:J04039 SP:P11585 PID:147562 PID:882678 GB:U00096
NP_438499.1	similar to GB:U00006 SP:P00556 GB:K00127 PID:396377 PID:457112
NP_438500.1	forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis
NP_438501.1	similar to GB:U00096 PID:1788904 PID:1799977
NP_438502.1	similar to GB:U00096 PID:1787885
NP_438503.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
NP_438504.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
NP_438505.1	similar to SP:P38521 PID:882488 GB:U00096 PID:1789329
NP_438507.1	similar to SP:P33938 PID:405935 GB:U00096 PID:1788535
NP_438509.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway
NP_438510.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA
NP_438511.1	contains two heme groups; similar to SP:P33933 PID:405928 GB:U00096 PID:1788531
NP_438512.1	similar to SP:P33932 PID:405927 GB:U00096 PID:1788530
NP_438513.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
NP_438514.1	similar to GB:U00096 SP:P36670 PID:1773117 PID:1786636 PID:563855
NP_438515.1	similar to SP:P24325 GB:L42023 PID:1003592 PID:1222277 PID:43589
NP_438516.1	similar to SP:P24324 GB:X57315 PID:43588
NP_438517.1	similar to PID:1184189 GB:U00096 SP:Q47538 PID:1384059 PID:1657561
NP_438518.1	similar to GB:L16808 SP:P40401 PID:438473 PID:1903040 GB:AL009126
NP_438519.1	similar to SP:P42883 SP:P43534 SP:P47183 PID:1015913 PID:1302455
NP_438520.1	similar to GB:AE000511 PID:2314455
NP_438521.1	similar to PID:1245464 SP:Q56955 PID:1245467
NP_438522.1	similar to PID:1245464 SP:Q56954 PID:1245466
NP_438523.1	similar to PID:1245464 PID:1245465
NP_438524.1	similar to PID:1245464
NP_438525.1	similar to SP:P33364 GB:X01067 PID:405864 PID:808967 GB:U00096
NP_438526.1	23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance
NP_438527.1	similar to PID:1162960
NP_438528.1	similar to SP:P27434 GB:D21149 GB:U02965 GB:X64451 PID:41541
NP_438529.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
NP_438530.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
NP_438531.1	similar to GB:U00096 PID:1788860
NP_438532.1	similar to SP:P37096 GB:U00096 PID:1788873
NP_438533.1	similar to GB:M88654 SP:P25528 PID:145915 GB:U00096 PID:1788874
NP_438534.1	involved in the maturation of iron-sulfur cluster-containing proteins
NP_438536.1	J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins
NP_438537.1	similar to SP:P36539
NP_438538.2	similar to PID:2271522
NP_438539.2	catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis
NP_438540.1	similar to GB:U00096 PID:1788880
NP_438541.1	similar to GB:U00096 PID:1788881
NP_438542.1	similar to SP:P10324 PID:1573351 SP:P10324 GB:M18878 PID:1573351
NP_438543.1	forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA
NP_438544.1	inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins
NP_438545.1	membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins
NP_438546.1	similar to SP:P05828 PID:1128978 GB:U00096 PID:1651329 PID:1786958
NP_438547.1	similar to SP:P08999 PID:1128977 GB:U00096 PID:1786957
NP_438548.1	similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110
NP_438549.1	similar to GB:U00096 SP:P76256 PID:1736440 PID:1736446 PID:1788109
NP_438550.1	similar to GB:U00039 SP:P37194 GB:L23635 PID:387932 PID:466643
NP_438551.1	Activates fatty acids by binding to coenzyme A
NP_438552.1	similar to SP:P09155 GB:X07055 GB:X70994 PID:581071 PID:581215
NP_438555.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
NP_438556.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
NP_438557.1	similar to PID:1033114 SP:P52119 GB:U00096 PID:1788971
NP_438558.1	similar to SP:P27431 GB:U00096 PID:1787373
NP_438559.1	bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
NP_438560.2	similar to SP:P36651 PID:882564 GB:U00096 PID:1789412
NP_438561.1	similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096
NP_438562.1	similar to GB:U00096 PID:1788685
NP_438563.1	similar to GB:M60607 SP:P10384 GB:Y00552 PID:145910 PID:41372
NP_438564.1	dat1; similar to SP:P11742 GB:X15659 PID:39876 GB:AL009126
NP_438565.1	MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair
NP_438566.1	similar to GB:U00096 PID:1552765 PID:1786386 PID:971394
NP_438567.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal
NP_438568.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
NP_438569.1	similar to PID:1054959 GB:U00096 PID:1788166
NP_438570.1	similar to SP:P52648 GB:U00096 PID:1736501 PID:1736505 PID:1788165
NP_438571.1	similar to GB:M77039 SP:P24204 PID:146890 PID:1054957 GB:U00096
NP_438572.1	contains a C-terminal HTH DNA-binding domain; similar to GB:M12114 SP:P07604 PID:148092 GB:U00096 PID:1742168
NP_438573.1	Stimulates the elongation of poly(A) tails
NP_438574.1	catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA
NP_438575.2	similar to SP:P21513 GB:X67470 GB:L23942 GB:M62747 GB:X54309
NP_438577.1	catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP
NP_438578.1	catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine
NP_438579.1	Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate
NP_438580.1	similar to GB:L42023 SP:P44610 PID:1003458 PID:1222206 PID:1204537
NP_438581.1	similar to GB:U00096 SP:P76403 PID:1736789 PID:1736801 PID:1788397
NP_438583.1	facilitates an early step in the assembly of the 50S subunit of the ribosome
NP_438584.1	similar to SP:P31825 GB:U00096 PID:1788929
NP_438585.1	similar to SP:P33635 GB:U00096 PID:1788935
NP_438586.1	catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome
NP_438587.1	Multifunctional regulator of fatty acid metabolism
NP_438588.2	involved in regulation of intracellular pH under alkaline conditions
NP_438589.1	disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein
NP_438590.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NP_438591.2	similar to SP:P02342 GB:D12624 GB:X05994 PID:216565 PID:396339
NP_438592.1	similar to SP:P32680 PID:396338 GB:U00096 PID:1790432
NP_438593.1	can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates
NP_438594.1	cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source
NP_438595.1	similar to GB:M59751 SP:P31773 PID:1573409
NP_438596.1	similar to GB:M62809 SP:P31772 PID:1573410
NP_438597.1	similar to GB:M62809 SP:P31771 PID:1573411
NP_438598.1	similar to GB:M62809 SP:P31770 PID:1573412
NP_438599.1	similar to GB:M62809 SP:P31769 PID:1573413
NP_438600.1	similar to GB:M62809 SP:P31768 PID:1573414
NP_438601.1	similar to SP:P02918 GB:X02164 PID:581194 PID:606330 GB:U00096
NP_438602.1	OrfJ; similar to GB:M62809 SP:P31777 PID:1573417
NP_438603.2	forms homodimers; coexpressed with recR; similar to GB:M38777 SP:P17577 GB:X04487 PID:145298 PID:43322
NP_438604.1	involved in a recombinational process of DNA repair, independent of the recBC complex
NP_438605.1	decatenates replicating daughter chromosomes
NP_438606.1	similar to GB:D16463 SP:P33582 GB:U01376 PID:431135 PID:606113
NP_438607.1	similar to SP:P20966 GB:M23196 PID:405893 PID:450372 GB:U00096
NP_438608.1	converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers
NP_438609.1	phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr
NP_438611.1	similar to GB:L22307 GB:L31763 GB:M74565 PID:145067 PID:438533
NP_438612.1	similar to PID:1196479
NP_438613.1	similar to GB:U14003 SP:P39319 PID:537059 GB:U00096 PID:1790664
NP_438614.1	similar to GB:AE000511 PID:2313105
NP_438615.1	similar to SP:P37346 GB:U00096 PID:1787342
NP_438616.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA
NP_438617.2	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
NP_438618.1	similar to GB:U00096 PID:1510185 PID:1787339
NP_438619.1	similar to SP:P21202 GB:M68521 PID:147119 PID:216478 GB:U00096
NP_438620.1	regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity
NP_438621.1	functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era
NP_438622.1	similar to SP:P32181
NP_438623.1	similar to GB:M38347 SP:P08177 GB:J03896 GB:L12349 GB:L20572
NP_438624.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
NP_438625.1	Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway
NP_438626.1	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate
NP_438627.1	similar to PID:887848 GB:U00096 SP:P39179 PID:1789265
NP_438628.3	similar to GB:L10328 SP:P23839 GB:X14235 PID:290494 PID:42721
NP_438629.1	long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors
NP_438630.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
NP_438631.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
NP_438632.1	catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate
NP_438633.1	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
NP_438634.1	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide
NP_438635.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
NP_438636.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis
NP_438637.1	similar to GB:M23240 SP:P18199 PID:148089 GB:U00096 PID:1736569
NP_438638.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
NP_438639.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
NP_438640.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
NP_438641.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
NP_438642.1	Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
NP_438643.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.
NP_438644.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0
NP_438645.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
NP_438646.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
NP_438647.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
NP_438649.1	similar to GB:U00096 PID:1789046
NP_438650.1	similar to GB:U00096 PID:1789045
NP_438651.1	catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
NP_438652.1	similar to GB:M29945 PID:1197032
NP_438653.1	Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity
NP_438654.1	heat shock protein involved in degradation of misfolded proteins
NP_438655.1	heat shock protein involved in degradation of misfolded proteins
NP_438656.2	similar to GB:M64519 SP:P23861 PID:147329 GB:U00096 PID:1651550
NP_438657.1	similar to GB:M38433 SP:P37906 PID:1054921 PID:551780 GB:U00096
NP_438658.2	similar to GB:M87049 SP:P27850 PID:148230 GB:U00096 PID:1790266
NP_438659.1	cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source
NP_438660.1	with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain
NP_438661.1	functions to transport ribose at high affinity; forms a complex with RbsA2C2B
NP_438662.1	periplasmic substrate-binding component of the ATP-dependent ribose transport system
NP_438663.1	catalyzes the formation of D-ribose 5-phosphate from ribose
NP_438664.1	similar to GB:L10328 SP:P25551 GB:D10466 GB:M13169 PID:147517
NP_438665.1	similar to PID:882531 SP:P52082 GB:U00096 PID:1789376
NP_438666.1	regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity
NP_438667.2	catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate
NP_438668.1	similar to GB:D15061 SP:P28634 PID:303558 GB:U00096 PID:1552771
NP_438669.1	similar to GB:M74072 SP:P25396 PID:149017 GB:U00096 PID:1742325
NP_438670.1	HincIIR; HindIIR; binds gtyrac palindromes as a dimer; similar to GB:X52124 SP:P17743 PID:1573497
NP_438671.1	similar to SP:P17744
NP_438672.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
NP_438673.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
NP_438674.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
NP_438675.1	binds directly to 23S ribosomal RNA
NP_438676.1	catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate
NP_438677.1	similar to GB:AE000511 PID:2314337
NP_438678.1	similar to GB:U14003 SP:P39409 PID:537219 GB:U00096 PID:1790839
NP_438679.1	similar to GB:U14003 SP:P37342 PID:537220 GB:U00096 PID:1790840
NP_438680.1	similar to GB:D26185 SP:P37505 PID:467358 GB:AL009126
NP_438681.2	similar to GB:AE000511 PID:2314449
NP_438682.1	catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate
NP_438683.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
NP_438685.1	similar to SP:P00208
NP_438686.1	similar to GB:M23240 SP:P18199 PID:148089 GB:U00096 PID:1736569
NP_438687.2	catalyzes the formation of thymidine 5'-phosphate from thymidine
NP_438688.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
NP_438689.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
NP_438690.1	synthesizes RNA primers at the replication forks
NP_438691.1	similar to GB:J01687 SP:P00579 PID:147756 PID:882590 PID:1072030
NP_438692.1	catalyzes the formation of fumarate from aspartate
NP_438693.1	similar to GB:M84338 SP:Q09067 PID:485336 PID:1247672 GB:AE000511
NP_438694.1	similar to GB:M84338 SP:Q09066 PID:485335 PID:1247672 GB:AE000511
NP_438695.2	similar to SP:Q07402 PID:393298
NP_438696.1	involved in the assembly of the urease metallocenter; possible nickel donor
NP_438697.1	ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits
NP_438698.1	ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active
NP_438699.1	UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter
NP_438700.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
NP_438701.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
NP_438702.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
NP_438703.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
NP_438704.2	binds single-stranded DNA at the primosome assembly site
NP_438705.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
NP_438706.2	stimulates the activities of the other two initiation factors, IF-2 and IF-3
NP_438707.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
NP_438708.1	similar to GB:X56903 GB:L19441
NP_438709.1	hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP
NP_438711.1	catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate
NP_438713.1	similar to GB:M87483 SP:Q02009 PID:551879
NP_438715.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
NP_438716.1	similar to SP:P22255 GB:M55170 GB:M80795 PID:145275 PID:145690
NP_438718.1	similar to PID:1655665
NP_438719.1	similar to SP:P45802 PID:606334 GB:U00096 PID:1789803
NP_438720.1	transcriptional repressor of asnA which codes for aspartate-ammonia ligase
NP_438721.1	catalyzes the formation of asparagine from aspartate and ammonia
NP_438722.1	catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate
NP_438723.2	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
NP_438724.1	negatively supercoils closed circular double-stranded DNA
NP_438725.1	similar to SP:Q45388 PID:1477402
NP_438726.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NP_438727.1	negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis
NP_438728.1	Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA
NP_438729.1	contains peroxiredoxin and glutaredoxin domains; forms homotetramers; similar to PID:1652858
NP_438730.1	similar to GB:L13261 SP:P30857 PID:290468 PID:606282 GB:U00096
NP_438731.1	similar to SP:P45523 SP:P45527 PID:606281 PID:862300 GB:U00096
NP_438732.1	similar to SP:P45533 PID:606280 GB:U00096 PID:1789744
NP_438733.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
NP_438734.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
NP_438736.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
NP_438737.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
NP_438738.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
NP_438739.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
NP_438740.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
NP_438741.1	periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate
NP_438742.1	similar to GB:U00096 SP:P77357 PID:1742205 PID:1742209 PID:1787599
NP_438745.2	alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family
NP_438746.1	allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide
NP_438747.1	similar to SP:P46187 PID:987645 PID:1045631 PID:1050877 GB:U00096
NP_438748.1	catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system
NP_438749.1	similar to GB:M64495 SP:P24169 PID:147331 GB:U00096 PID:1651300
NP_438751.1	similar to GB:AE000783
NP_438752.1	reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP
NP_438753.1	similar to GB:X05637 SP:P08308 PID:45288
NP_438754.1	similar to SP:P27848
NP_438755.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
NP_438756.2	binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities
NP_438757.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
NP_438758.1	similar to GB:U13205 PID:1573592
NP_438760.1	similar to GB:M87049 SP:P09128 GB:X12614 PID:148201 PID:41669
NP_438762.1	catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP
NP_438763.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
NP_438764.1	catalyzes the O-acetylation of serine
NP_438765.1	catalyzes the conversion of shikimate to 3-dehydroshikimate
NP_438766.1	similar to GB:L77117 SP:Q58086 PID:1591386
NP_438767.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
NP_438768.1	similar to SP:P11551 GB:X15025 PID:146041 PID:41504 PID:882696
NP_438769.1	catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate
NP_438770.1	similar to PID:882699 GB:U00096 PID:1789169
NP_438771.1	similar to SP:P11553 GB:X15025 PID:41506 PID:882698 GB:U00096
NP_438772.2	catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose
NP_438773.1	similar to SP:P11554 GB:X15025 PID:41508 PID:882700 GB:U00096
NP_438774.1	transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA
NP_438775.1	similar to SP:P39219 GB:U00096 PID:1786244
NP_438776.1	similar to GB:M54940 SP:P09391 GB:M96795 PID:146185 PID:146193
NP_438777.1	similar to SP:P09392 GB:M96795 PID:146186 PID:606358 GB:U00096
NP_438778.1	similar to GB:M59804 SP:P31728 PID:1573614
NP_438780.1	part of the metNIQ transport system for methionine
NP_438781.1	Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate
NP_438782.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
NP_438783.1	modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth
NP_438784.1	similar to SP:P36929 SP:P36929 GB:X52114 PID:43136 PID:443992
NP_438785.1	involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain
NP_438786.1	forms homopentamer; channel that opens in response to pressure or hypoosmotic shock
NP_438787.1	similar to PID:887847 GB:U00096 SP:Q46825 PID:1789264
NP_438788.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response
NP_438789.1	similar to SP:P38106 GB:U10148 GB:U00096 PID:1788925 PID:987647
NP_438790.1	periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP
NP_438791.1	catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis
NP_438792.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
NP_438794.1	similar to SP:P32695 PID:396384 GB:U00096 PID:1790483
NP_438795.2	similar to PID:1000292 PID:984513
NP_438796.1	similar to GB:U00096 PID:1788685
NP_438797.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_438798.1	HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis
NP_438799.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
NP_438800.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
NP_438801.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
NP_438802.1	forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
NP_438803.1	similar to SP:P46923 PID:1045667 GB:U00096 PID:1736518 PID:1736526
NP_438804.2	similar to SP:P52005 GB:U00096 PID:1736519 PID:1736527 PID:1788181
NP_438805.1	similar to PID:1449198
NP_438806.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
NP_438807.1	similar to GB:M57715 SP:P22037 PID:154179
NP_438808.2	similar to SP:P40717 PID:609328 PID:882558 GB:U00096 PID:1789406
NP_438809.1	similar to GB:M87049 SP:P09980 GB:X04794 PID:148182 GB:U00096
NP_438811.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
NP_438812.1	catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A
NP_438813.1	similar to PID:1389735
NP_438814.1	similar to SP:P05100 GB:J02606 GB:X03845 PID:147920 PID:43030
NP_438815.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
NP_438816.1	similar to SP:P45748 PID:606216 GB:U00096 PID:2367210
NP_438817.1	similar to SP:P45771 PID:606217 GB:U00096 PID:1789677
NP_438818.1	similar to SP:P45535 PID:606286 GB:U00096 PID:1789751
NP_438821.1	similar to PID:1000292 PID:984513
NP_438823.1	similar to GB:AL009126
NP_438827.1	type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese
NP_438828.1	similar to GB:L19201 SP:P32164 PID:305031 GB:U00096 PID:1790363
NP_438829.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
NP_438830.1	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine
NP_438831.1	catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate
NP_438832.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
NP_438833.1	forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein
NP_438834.1	catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively
NP_438835.1	similar to GB:M34034 SP:P15288 GB:X14790 PID:1208983 PID:147140
NP_438836.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
NP_438838.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
NP_438839.1	similar to GB:X07520 SP:P09390 GB:M96795 PID:146184 PID:146192
NP_438840.1	similar to SP:P27844
NP_438841.1	participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate
NP_438842.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
NP_438843.1	anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate
NP_438844.1	sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters
NP_438845.1	anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor
NP_438846.1	similar to SP:P08194 GB:Y00536 PID:41587 GB:U00096 PID:1788573
NP_438847.1	similar to GB:D26185 SP:P37511 PID:467365 GB:AL009126
NP_438849.1	hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic
NP_438850.1	similar to GB:L19201 SP:P11244 GB:M55990 GB:U13915 GB:X15054
NP_438851.1	Converts glycerol and ADP to glycerol-3-phosphate and ADP
NP_438852.1	catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively
NP_438853.1	similar to GB:M68502 SP:P26093 PID:1573696
NP_438854.1	similar to GB:U00096 SP:P75966 PID:1787380
NP_438855.1	similar to GB:L06129 SP:P29014 PID:147343 GB:U00096 PID:1788848
NP_438856.1	similar to GB:U14003 SP:P39321 PID:537063 GB:U00096
NP_438857.1	similar to GB:U14003 SP:P39320 PID:537061 GB:U00096 PID:1790666
NP_438858.1	similar to GB:L13261 SP:P30856 GB:Z21496 PID:394720 PID:475995
NP_438859.1	similar to SP:P37163 GB:U14003 PID:537096 GB:U00096 PID:1790704
NP_438860.1	catalyzes the modification of U13 in tRNA(Glu)
NP_438861.1	catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate
NP_438862.1	similar to GB:L10653 SP:P36684 PID:148929
NP_438864.1	similar to GB:L07869 SP:P33648 PID:404099 PID:433185 PID:882635
NP_438865.1	This protein performs the mismatch recognition step during the DNA repair process
NP_438866.1	catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis
NP_438867.1	similar to SP:P14081 GB:X16644 PID:42937 PID:466728 GB:U00096
NP_438869.1	similar to PID:984581 GB:U00096 SP:Q47149 PID:1786419
NP_438870.1	similar to PID:1000292 PID:984513
NP_438871.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
NP_438872.3	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
NP_438873.1	binds and unfolds substrates as part of the ClpXP protease
NP_438874.1	forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
NP_438875.1	Modulates Rho-dependent transcription termination
NP_438876.1	similar to SP:P43262 PID:904221
NP_438877.1	unknown function; forms homotrimers; binds small molecules of alpha-keto acids or alpha,beta-unsaturated acids; similar to GB:U14003 SP:P39330 PID:537085 GB:U00096 PID:1790691
NP_438878.1	metalloprotease
NP_438879.2	TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs
NP_438880.2	similar to GB:U00096 PID:1790283
NP_438881.1	similar to GB:M87049 SP:P21166 PID:148249 PID:42359 PID:2367317
NP_438882.1	similar to PID:1685095
NP_438883.1	similar to PID:1685094
NP_438884.1	similar to GB:U00008 SP:P31802 GB:L11273 PID:304917 PID:405947
NP_438885.1	similar to SP:P19572
NP_438886.1	defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly
NP_438887.1	similar to GB:M87049 SP:P15043 GB:M30198 PID:147559 PID:148221
NP_438888.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
NP_438889.1	determines N-hexane tolerance and is involved in outer membrane permeability
NP_438893.1	similar to GB:M63491 SP:P26647 PID:147298 PID:882548 GB:U00096
NP_438894.1	catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine
NP_438895.1	similar to GB:AE000782
NP_438896.1	similar to GB:M10313 SP:P00892 GB:M32253 GB:V00290 GB:X04890
NP_438897.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
NP_438898.1	threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway
NP_438899.1	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase
NP_438900.2	similar to GB:M34393 SP:P18159 PID:142994 PID:2226139 GB:AL009126
NP_438902.1	molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA
NP_438903.1	similar to SP:P37688 PID:466749 GB:U00096 PID:1790040
NP_438904.1	catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis
NP_438905.1	functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB
NP_438906.1	similar to SP:P00393 PID:581140 GB:U00096 PID:1651546 PID:1787352
NP_438907.1	PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA
NP_438908.2	Represses a number of genes involved in the response to DNA damage
NP_438909.1	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
NP_438910.1	antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein
NP_438911.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
NP_438912.1	catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling
NP_438913.1	catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway
NP_438914.2	similar to SP:P37691 PID:912478 GB:U00096 PID:1790043
NP_438915.1	similar to SP:P37690 PID:466751 GB:U00096 PID:1790042
NP_438916.1	2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate
NP_438917.1	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
NP_438918.1	similar to GB:M59471 SP:P17802 GB:X52391 PID:146864 PID:42073
NP_438919.1	similar to PID:882491 SP:P52065 GB:U00096 PID:1789332
NP_438920.1	Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues
NP_438922.1	catalyzes the formation of NAD(+) from nicotinamide ribonucleotide
NP_438923.1	DHBP synthase; functions during riboflavin biosynthesis
NP_438924.2	similar to GB:M37913 GB:L19441 PID:1573535
NP_438925.1	YibK; binds cofactor S-adenosylhomocysteine; similar to SP:P33899 PID:466744 GB:U00096 PID:1790034
NP_438926.1	similar to SP:P10120 GB:U00039 GB:X04398 PID:41497 PID:466601
NP_438927.1	similar to SP:P10121 GB:U00039 GB:X04398 PID:41498 PID:466600
NP_438928.1	similar to SP:P10115 GB:U00039 GB:X04398 PID:41499 PID:466599
NP_438929.1	ABC transporter, membrane protein
NP_438930.1	similar to GB:U00096 SP:P76461 PID:1736879 PID:1788554 PID:1799573
NP_438931.1	similar to GB:U00096 SP:P76460 PID:1788553
NP_438932.1	similar to GB:U00096 SP:P76459 PID:1736877 PID:1788552
NP_438933.1	similar to GB:U00096 SP:P76458 PID:1736876 PID:1788551
NP_438934.2	similar to GB:X73124 SP:P39592 PID:413948 GB:AL009126
NP_438935.2	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
NP_438936.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
NP_438937.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
NP_438938.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
NP_438939.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
NP_438940.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NP_438941.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
NP_438942.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
NP_438943.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
NP_438944.1	one of the stabilizing components for the large ribosomal subunit
NP_438945.1	primary binding protein; helps mediate assembly; involved in translation fidelity
NP_438947.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
NP_438948.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
NP_438949.3	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
NP_438950.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif
NP_438951.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NP_438952.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
NP_438953.1	binds 5S rRNA along with protein L5 and L25
NP_438954.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
NP_438955.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
NP_438956.1	late assembly protein
NP_438957.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
NP_438958.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif
NP_438959.3	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
NP_438960.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
NP_438961.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
NP_438962.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
NP_438963.1	is a component of the macrolide binding site in the peptidyl transferase center
NP_438966.1	similar to GB:L77117 SP:Q57883 PID:1591145
NP_438967.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
NP_438968.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
NP_438969.1	PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP
NP_438970.1	becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers
NP_438971.1	catalyzes the formation of arginine from (N-L-arginino)succinate
NP_438972.1	similar to GB:M98830 SP:P25520 GB:X59940 PID:146073 PID:42026
NP_438973.1	affects carbohydrate metabolism; has regulatory role in many processes
NP_438974.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_438975.1	forms asymmetric homodimer; similar to GB:U00039 SP:P28242 GB:X67639 PID:43280 PID:466632
NP_438976.1	similar to GB:D00398 SP:P15034 PID:216529 PID:216627 PID:882438
NP_438977.1	the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown
NP_438978.1	catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose
NP_438979.2	catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism
NP_438980.1	catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P
NP_438981.1	similar to SP:P31766 GB:X65934 PID:1573834
NP_438982.2	similar to SP:P02927 GB:K00419 GB:X05646 PID:146853 PID:146857
NP_438983.1	with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains
NP_438984.1	ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex
NP_438986.1	Involved in cell division; probably involved in intracellular septation
NP_438987.1	similar to GB:K00431 SP:P04379 PID:455187 PID:902382 PID:902391
NP_438988.1	unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity
NP_438989.1	similar to GB:U14003 SP:P03810 GB:M69185 PID:147836 PID:537232
NP_438990.1	When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription
NP_438991.2	glycosyltransferase; polymerizes glycan strands in the peptidoglycan
NP_438992.1	in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane
NP_438993.2	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
NP_438994.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
NP_438995.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
NP_438996.2	lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
NP_438997.1	similar to GB:L19201 SP:P16244 GB:L14579 GB:X13307 PID:145589
NP_438998.2	similar to SP:P23089
NP_438999.2	similar to SP:P33920 PID:405914 GB:U00096 PID:1788513
NP_439000.1	similar to SP:P33921 PID:405915 GB:U00096 PID:1788514
NP_439001.1	similar to SP:P33922 PID:453987 GB:U00096 PID:1788515
NP_439004.1	in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis
NP_439005.1	similar to GB:L19201 SP:P32126 PID:304964 GB:U00096 PID:1790289
NP_439006.1	similar to GB:M94205 SP:P31810 PID:1573860
NP_439007.1	similar to GB:M87049 SP:P27827 PID:148172 GB:U00096 PID:2367277
NP_439008.1	catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs
NP_439010.1	similar to SP:P46187 PID:987645 PID:1045631 PID:1050877 GB:U00096
NP_439011.1	similar to GB:L19201 SP:P32125 PID:304962 GB:U00096 PID:1790287
NP_439012.1	similar to GB:L10328 SP:P31474 PID:290604 GB:U00096 PID:1790195
NP_439013.1	similar to GB:M84028 SP:P33950 PID:1573869
NP_439014.1	similar to GB:AE000511 PID:2313418
NP_439015.1	similar to SP:P42626 PID:606050 GB:U00096 PID:1789496
NP_439016.1	has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair
NP_439017.1	similar to SP:P45580 PID:882440 GB:U00096 PID:1789277
NP_439018.1	similar to GB:M12965 SP:P09160 PID:147874 PID:882441 GB:U00096
NP_439019.1	similar to GB:M29364 SP:P03815 GB:V00350 GB:X57620 PID:1236633
NP_439020.1	Specifically methylates the ribose of guanosine 2251 in 23S rRNA
NP_439021.1	exoribonuclease R; similar to GB:U14003 SP:P21499 PID:537020 GB:U00096 PID:1790622
NP_439022.1	similar to SP:P37619 PID:466607 GB:U00096 PID:1789882
NP_439023.2	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate
NP_439024.1	similar to GB:L19201 SP:P32132 PID:304976 GB:U00096 PID:1790302
NP_439025.1	similar to SP:P28786 GB:X68129 PID:45900
NP_439027.1	similar to SP:P37781 PID:454902
NP_439028.1	similar to GB:AL009126
NP_439033.1	similar to SP:P26406 GB:X52093 PID:1335815 PID:1335817
NP_439034.2	similar to GB:M87049 SP:P27830 PID:148191 GB:U00096 PID:1790223
NP_439037.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
NP_439038.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
NP_439039.1	similar to SP:P28636 PID:216638 PID:606122 GB:U00096 PID:1789575
NP_439040.1	involved in the peptidyltransferase reaction during translation
NP_439041.1	similar to GB:D13267 SP:P02422 PID:216636 PID:606124 GB:U00096
NP_439042.1	similar to SP:P19641 GB:X68873 PID:388220 PID:606125 GB:U00096
NP_439044.1	similar to PID:757741 SP:Q45068 PID:1405464 GB:AL009126
NP_439045.1	similar to SP:P03026 GB:L34010 GB:M10044 PID:1790863
NP_439046.1	two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm
NP_439048.1	involved in de novo purine biosynthesis
NP_439049.1	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
NP_439050.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
NP_439051.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
NP_439053.1	enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation
NP_439054.1	Bm3T1; similar to GB:S87512 SP:P43506 PID:623036 PID:247052
NP_439055.1	similar to GB:U14993 SP:P43505 PID:438192 PID:550460
NP_439056.1	similar to GB:M94248 SP:P31224 GB:U00734 PID:290406 PID:532311
NP_439057.1	similar to GB:L19201 SP:P29131 GB:L14281 PID:290448 PID:305036
NP_439058.1	similar to GB:M86657 SP:P27304 PID:145836 GB:U00096 PID:1789042
NP_439059.1	similar to GB:M86657 SP:P27303 PID:145835 GB:U00096 PID:1789041
NP_439060.1	similar to GB:D10483 SP:P00379 GB:J01609 GB:J01609 GB:X05108
NP_439061.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
NP_439062.1	hydrolyzes diadenosine polyphosphate
NP_439063.1	similar to GB:L77117 SP:Q57883 PID:1591145
NP_439064.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
NP_439065.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
NP_439066.1	similar to SP:P30134 PID:296183 PID:987637 PID:1033148 GB:U00096
NP_439069.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
NP_439070.1	MutT; similar to GB:D10483 SP:P08337 GB:M20791 GB:X04831 PID:147795
NP_439071.1	similar to GB:D10483 SP:P03819 GB:X56742 PID:216472 PID:41875
NP_439073.2	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
NP_439074.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
NP_439075.1	adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis
NP_439076.1	similar to PID:1935023
NP_439077.1	similar to GB:U13961 PID:1573938 PID:2231192 PID:2231195
NP_439078.1	similar to SP:P37764 PID:1208948 GB:U00096 PID:1552753 PID:1786373
NP_439079.1	similar to GB:M11330 SP:P06466 PID:1208947 PID:145476 GB:U00096
NP_439080.1	similar to PID:1208946 GB:U00096 SP:Q47675 PID:1552751 PID:1786371
NP_439081.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
NP_439082.2	similar to GB:M18277 SP:P10101 PID:147663 GB:U00096 PID:1651268
NP_439083.1	required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA
NP_439084.1	glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
NP_439085.1	similar to SP:P45736 GB:U00096 PID:1279405 PID:1787546
NP_439087.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
NP_439088.1	similar to GB:U02682 PID:1573949
NP_439089.1	similar to GB:M77129 SP:P24196 PID:146678 PID:882568 GB:U00096
NP_439092.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
NP_439093.1	similar to SP:P37631 PID:912464 GB:U00096 PID:2367234
NP_439094.1	similar to SP:P32711 GB:X72298 PID:396410 PID:404307 GB:U00096
NP_439095.1	similar to SP:P33926 PID:405920 GB:U00096 PID:1788523
NP_439096.1	similar to SP:P32710 GB:X72298 PID:581146 GB:U00096 PID:1790511
NP_439097.1	similar to GB:M34828 SP:P22783 PID:147899 GB:U00096 PID:1788882
NP_439102.1	similar to SP:P07648 PID:42689 PID:882714 GB:U00096 PID:1789186
NP_439103.1	similar to SP:P25538 GB:X64395 PID:42148 GB:U00096 PID:1773097
NP_439104.1	similar to SP:P25539 GB:X64395 PID:581147 GB:U00096 PID:1773098
NP_439105.1	similar to SP:P31137 GB:U15661 GB:U00096 PID:1789630
NP_439106.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
NP_439107.1	similar to PID:893355
NP_439108.1	similar to GB:L22308 GB:L31763 GB:M74565 PID:145068 PID:438534
NP_439109.1	similar to SP:P18355
NP_439110.1	catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde
NP_439111.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
NP_439112.1	required for 70S ribosome assembly
NP_439113.2	Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase
NP_439114.1	catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine
NP_439115.1	catalyzes the formation of dUMP from dUTP
NP_439116.1	FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly
NP_439118.1	complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons
NP_439119.1	RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA
NP_439120.1	hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
NP_439122.2	similar to SP:P44956
NP_439124.1	catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities
NP_439125.1	similar to GB:D25292 SP:P37169 GB:Z26133 PID:438252 PID:505363
NP_439126.2	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
NP_439129.1	catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA
NP_439130.2	catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate
NP_439131.1	catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis
NP_439132.1	composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NP_439133.1	an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NP_439136.1	similar to SP:P45566 PID:606197 GB:U00096 PID:1789655
NP_439137.1	mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase
NP_439140.1	similar to GB:M28363 SP:P20605 PID:145955 PID:147054 PID:606295
NP_439141.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
NP_439142.1	similar to SP:P45672 PID:599600
NP_439143.1	Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription
NP_439144.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
NP_439145.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
NP_439147.2	similar to GB:D10483 SP:P11288 PID:216438 PID:537248 PID:1128976
NP_439148.1	similar to GB:L42023 SP:P43862 PID:1006171 PID:1221098 PID:609332
NP_439149.2	catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis
NP_439150.1	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis
NP_439151.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
NP_439152.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
NP_439153.1	similar to GB:M87489
NP_439154.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
NP_439155.1	binds the polymerase to DNA and acts as a sliding clamp
NP_439156.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
NP_439157.1	similar to GB:Z15129 SP:Q06987 GB:S64486 GB:X75168 PID:297044
NP_439158.1	similar to PID:1177569
NP_439160.1	in Escherichia coli transcription of this gene is enhanced by polyamines
NP_439161.1	protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
NP_439162.1	similar to PID:1005414
NP_439163.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
NP_439164.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
NP_439165.2	contains frameshifts; similar to GB:U00096 SP:P77241 PID:1580712 PID:1773125 PID:1786645
NP_439166.1	similar to HI1064; similar to GB:U00096 SP:P75785 PID:1787035
NP_439167.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
NP_439168.1	catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway
NP_439169.1	similar to GB:U00096 SP:P77415 PID:1580713 PID:1773126 PID:1786646
NP_439170.1	similar to SP:P09392 GB:M96795 PID:146186 PID:606358 GB:U00096
NP_439171.1	similar to PID:882629 GB:U00096 PID:1789092
NP_439172.1	similar to PID:882630 GB:U00096 PID:1789093
NP_439173.1	similar to PID:882631 GB:U00096 SP:Q46890 PID:1789094
NP_439174.1	similar to PID:882632 GB:U00096 SP:Q46891 PID:1789095
NP_439175.1	similar to PID:695275
NP_439176.1	similar to SP:P39835 PID:606350 GB:U00096 PID:1789820
NP_439179.1	similar to GB:D10483 SP:P31550 GB:U09984 PID:216488 PID:497658
NP_439180.1	permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine
NP_439181.1	similar to GB:D10483 SP:P31548 PID:216486 GB:U00096 PID:1786253
NP_439182.1	similar to GB:J04423 SP:P12996 PID:145425 PID:490219 GB:U00096
NP_439183.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
NP_439184.1	catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization
NP_439185.1	catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NP_439186.1	L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate
NP_439187.1	similar to SP:P37677 PID:466718 GB:U00096 PID:1790005
NP_439188.1	similar to SP:P37676 PID:466717 GB:U00096 PID:1790004
NP_439189.1	similar to SP:P37675 PID:466716 GB:U00096 PID:1790003
NP_439190.1	similar to SP:P37674 PID:466715 GB:U00096 PID:1790002
NP_439191.1	NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate
NP_439192.1	similar to SP:P37671 PID:466712 GB:U00096 PID:1789999
NP_439193.1	catalyzes the formation of serine from O-phosphoserine
NP_439194.1	nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription
NP_439195.1	responsible for the influx of magnesium ions
NP_439196.2	similar to PID:801880 SP:P52059 PID:801882
NP_439197.1	similar to PID:984579 GB:U00096 SP:Q47147 PID:1552793 PID:1786417
NP_439198.1	similar to GB:L77117 PID:1592175
NP_439199.1	similar to SP:P25261 SP:P24599 PID:43474
NP_439200.1	similar to SP:P24600 SP:P25267 PID:43482
NP_439202.1	similar to SP:P33939 PID:453990 GB:U00096 PID:1736849 PID:1788536
NP_439203.1	binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane
NP_439204.1	similar to GB:J03412 SP:P18777 PID:145757 GB:U00096 PID:1651423
NP_439205.1	similar to GB:J03412 SP:P18776 PID:145756 GB:U00096 PID:1742612
NP_439206.1	similar to GB:J03412 SP:P18775 PID:145755 GB:U00096 PID:1651421
NP_439208.1	similar to SP:P04140 GB:Z00027 PID:154899 PID:43716
NP_439209.1	similar to PID:1143574 SP:Q54463
NP_439210.1	similar to GB:AL009126
NP_439211.1	similar to SP:P35319 PID:581707
NP_439212.1	similar to GB:M66060 SP:P27749 PID:141897
NP_439217.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
NP_439218.1	catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM
NP_439219.1	catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis
NP_439220.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
NP_439223.1	Catalyzes the phosphorylation of UMP to UDP
NP_439224.1	similar to SP:P32709 GB:X72298 PID:396408 PID:404305 GB:U00096
NP_439225.1	similar to SP:P32708 GB:X72298 PID:396407 PID:404304 GB:U00096
NP_439226.2	part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia
NP_439227.3	catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552
NP_439228.2	involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain
NP_439229.1	similar to SP:P32065 GB:U01030 GB:X73413 PID:312767 PID:523332
NP_439230.1	similar to GB:U00096 PID:1788090
NP_439231.1	similar to GB:J03939 SP:P11027 PID:145640 GB:U00096 PID:1651328
NP_439232.1	similar to GB:J03939 SP:P11026 PID:497637 GB:U00096 PID:1651327
NP_439233.1	CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
NP_439235.2	similar to SP:P39456
NP_439237.1	similar to SP:P42199
NP_439238.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
NP_439239.1	similar to SP:P43781 PID:606128 GB:U00096 PID:1789581
NP_439240.1	similar to GB:M34995 SP:P17903 GB:L35574 PID:143458 PID:1881281
NP_439241.1	similar to SP:P45390 PID:606130 GB:U00096 PID:1789583
NP_439242.1	similar to SP:P45391 PID:606131 GB:U00096 PID:1789584
NP_439243.1	similar to SP:P45392 PID:606132 GB:U00096 PID:1789585
NP_439244.1	similar to SP:P45393 PID:606133 GB:U00096 PID:1789586
NP_439245.1	similar to GB:X73832 PID:1574643
NP_439246.1	ATP-binding protein; required for proper cytochrome c maturation
NP_439247.1	similar to SP:P33930 PID:405925 GB:U00096 PID:1788528
NP_439248.1	similar to SP:P33929 PID:405924 GB:U00096 PID:1788527
NP_439249.1	similar to SP:P36770 PID:453988 GB:U00096 PID:1788526
NP_439250.1	CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane
NP_439251.1	similar to SP:P33927 PID:405921 GB:U00096 PID:1788524
NP_439252.1	similar to SP:P33926 PID:405920 GB:U00096 PID:1788523
NP_439257.2	this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB
NP_439258.1	interacts with cell division protein FitsZ and may be required to anchor septal ring structure
NP_439259.1	role in sulfur assimilation
NP_439260.1	similar to GB:M21451 SP:P11096 GB:X12615 PID:145686 PID:41201
NP_439261.1	similar to PID:1842056
NP_439262.1	similar to SP:P37692 PID:466758 GB:U00096 PID:1790050
NP_439263.1	similar to SP:P37390 PID:466707 GB:U00096 PID:1789993
NP_439264.1	similar to GB:U61539 SP:P27611 PID:143245 PID:2209268
NP_439266.1	similar to SP:P37389 PID:466706 GB:U00096 PID:1789992
NP_439267.1	with XylFH is part of the high affinity xylose ABC transporter
NP_439268.1	periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity
NP_439269.1	catalyzes the interconversion of D-xylose to D-xylulose
NP_439270.1	similar to PID:2293419
NP_439271.1	catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose
NP_439272.1	similar to PID:1213065 SP:P52229
NP_439273.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate
NP_439274.1	similar to GB:M37337 SP:P22787 PID:147774 PID:147775 PID:148173
NP_439275.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
NP_439276.1	similar to SP:P32181 GB:M59210 PID:387858
NP_439277.1	similar to GB:U00096 SP:P77737 PID:1742036 PID:1787500 PID:1805528
NP_439278.1	similar to SP:P04285 GB:X05491 GB:X52093 PID:47805
NP_439279.1	similar to SP:P08006 GB:X05491 GB:X52093 PID:47804
NP_439280.1	similar to GB:U00096 PID:1742033 PID:1787497 PID:1805525
NP_439281.1	similar to SP:P06202 GB:X05491 GB:X52093 PID:47802 PID:47808
NP_439282.1	Maintains the balance of metabolites in the pentose-phosphate pathway
NP_439287.1	MraZ; UPF0040; crystal structure shows similarity to AbrB
NP_439288.1	similar to GB:D10483 SP:P18595 GB:X52063 PID:216497 PID:40850
NP_439289.1	similar to SP:P22187 GB:K00137 GB:S49802 GB:S49875 GB:X52063
NP_439290.1	similar to GB:D10483 SP:P04286 GB:K00137 GB:S49802 GB:S49875
NP_439291.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
NP_439292.1	similar to GB:D10483 SP:P11880 PID:216500 PID:40854 PID:42048
NP_439293.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NP_439294.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
NP_439295.1	similar to GB:D10483 SP:P16457 GB:M30807 PID:146039 PID:216503
NP_439296.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
NP_439297.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
NP_439298.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
NP_439299.1	similar to GB:D10483 SP:P06136 GB:K02668 GB:X02821 PID:145725
NP_439300.1	similar to GB:D10483 SP:P06137 GB:K02668 GB:M36531 GB:X02821
NP_439301.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
NP_439302.1	zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis
NP_439303.1	similar to SP:Q02286 GB:M74134 GB:X60420 PID:148468 PID:43344
NP_439304.2	similar to SP:P33995 GB:Z27094 PID:414888 PID:551341 PID:606144
NP_439305.1	similar to GB:D12938 SP:P31222 GB:Z27094 PID:285783 PID:414887
NP_439306.1	similar to GB:D12938 SP:P31220 PID:285780 PID:551337 PID:606140
NP_439308.2	similar to SP:P45397 PID:606138 GB:U00096 PID:1789591
NP_439309.1	similar to SP:P26650 GB:M95096 PID:148266 PID:537076 GB:U00096
NP_439310.1	similar to SP:P24231 GB:X54152 PID:42440 PID:537077 GB:U00096
NP_439311.1	Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively
NP_439312.1	similar to GB:U00096 PID:1742823 PID:1742828 PID:1788024
NP_439313.1	activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions
NP_439314.1	in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c
NP_439315.1	in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c
NP_439316.1	similar to GB:J03762 SP:P09625 PID:148073 PID:347239 GB:U00096
NP_439317.2	contains frameshifts
NP_439318.1	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
NP_439319.1	similar to GB:M24143 SP:P15050 PID:450383 PID:522184 GB:U00096
NP_439320.1	similar to SP:P45736 GB:U00096 PID:1279405 PID:1787546
NP_439321.1	similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977
NP_439322.1	similar to GB:L20309 SP:P38368
NP_439323.2	similar to PID:2407233
NP_439324.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
NP_439325.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine
NP_439326.1	similar to GB:U00096 PID:1788317
NP_439329.1	catalyzes the formation of anthranilate from chorismate and glutamine; functions in tryptophan biosynthesis
NP_439330.1	methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
NP_439331.1	similar to SP:P39902 PID:1208420 PID:882473 GB:U00096 PID:1789313
NP_439332.2	similar to GB:X15780 PID:1333789
NP_439333.1	with ArtPQJI acts to transport arginine across the inner membrane
NP_439334.1	with ArtPMJI transports arginine across the inner membrane
NP_439335.1	similar to GB:M59210 SP:P49618 PID:387859
NP_439336.1	With ArtMQJI transports arginine across the inner membrane
NP_439337.1	catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate
NP_439340.1	Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides
NP_439341.1	DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF
NP_439342.1	similar to SP:P37315 PID:349227 PID:466681 GB:U00096 PID:1789964
NP_439343.2	similar to SP:P37316 PID:349226 PID:466682 GB:U00096 PID:1789965
NP_439344.1	unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.
NP_439345.1	similar to PID:1652793
NP_439346.1	similar to PID:882658 GB:U00096 SP:Q46903 PID:1789124
NP_439349.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
NP_439350.1	Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence
NP_439352.1	catalyzes the interconversion of succinyl-CoA and succinate
NP_439353.1	similar to GB:J01619 SP:P07459 PID:146204 PID:809679 GB:U00096
NP_439354.1	similar to SP:P45847 PID:602960 GB:U00096 PID:1787521
NP_439355.1	similar to PID:602963 GB:U00096 PID:1787524
NP_439356.1	LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation
NP_439357.1	involved in methylation of ribosomal protein L3
NP_439358.2	similar to GB:U00096 PID:1788671
NP_439359.1	catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate
NP_439360.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
NP_439361.1	similar to GB:U00096 PID:1788632 GB:U00096 PID:1788632
NP_439362.1	similar to GB:J01666 SP:P08550 PID:146367 PID:147415 GB:U00096
NP_439363.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
NP_439364.1	similar to GB:L42023 PID:1007092 PID:1221333 PID:1205451 PID:1574138
NP_439365.1	regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes
NP_439366.1	oxidizes malate to oxaloacetate
NP_439367.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
NP_439369.1	similar to GB:M54884 SP:P21892 PID:147549 PID:887843 GB:U00096
NP_439370.1	similar to GB:M54884 SP:P21893 PID:147550 PID:887842 GB:U00096
NP_439371.2	similar to PID:840949 SP:P50024
NP_439372.1	enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine
NP_439373.1	similar to PID:2764817
NP_439374.1	similar to GB:AE000782
NP_439375.2	Catalyzes the formation of (d)CDP from ATP and (d)CMP
NP_439376.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
NP_439377.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
NP_439378.1	similar to GB:U00096 PID:1787535
NP_439379.1	similar to SP:P45576 GB:U00096 PID:2367116
NP_439380.1	OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
NP_439381.1	involved in start site selection during the initiation of translation
NP_439382.1	controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP
NP_439383.1	similar to GB:X76083 SP:P41006 PID:431231
NP_439384.1	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate
NP_439385.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
NP_439386.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
NP_439387.1	E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
NP_439388.1	similar to GB:D26562 SP:P06959 GB:V01498 PID:434011 PID:473784
NP_439389.1	E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC
NP_439390.1	catalyzes the formation of methylglyoxal from glycerone phosphate
NP_439393.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
NP_439394.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
NP_439395.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
NP_439396.1	similar to GB:L10328 SP:P31432 PID:290496 GB:U00096 PID:1790078
NP_439398.1	Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance
NP_439399.1	similar to SP:P33918 PID:405907 GB:U00096 PID:1788510
NP_439401.1	NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate
NP_439403.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
NP_439407.1	similar to PID:1002991 PID:563265 SP:Q46560
NP_439408.1	ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence
NP_439409.1	similar to PID:968932 GB:U00096 PID:1787464
NP_439413.1	similar to SP:P30958 GB:U00096 PID:1651547 PID:1651549 PID:1787357
NP_439414.1	similar to SP:P39099 PID:558912 PID:606173 PID:984379 GB:U00096
NP_439415.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits
NP_439416.1	similar to GB:M68934 SP:P08192 GB:M32445 PID:146009 PID:146020
NP_439417.2	similar to SP:P33017 PID:405877 PID:1161522 GB:U00096 PID:1788466
NP_439418.1	Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine
NP_439419.1	negatively supercoils closed circular double-stranded DNA
NP_439420.1	similar to GB:U00096 SP:P75838 PID:1787133
NP_439425.1	similar to GB:AE000511 SP:O05732 PID:2072456 PID:2314024
NP_439426.1	similar to PID:1816658
NP_439427.1	similar to PID:1208973 GB:U00096 SP:Q47677 PID:1552782 PID:1786406
NP_439428.1	with TehA confers resistance to tellurite
NP_439429.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
NP_439430.2	similar to SP:P21590 GB:U00007 GB:X55791 PID:405896 PID:42017
NP_439431.1	similar to GB:D17743 SP:P46072 PID:517169
NP_439432.1	similar to GB:M95053 GB:X78068 GB:U04328 PID:460146 PID:520734
NP_439434.2	in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins
NP_439435.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
NP_439436.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NP_439437.1	similar to PID:1685100
NP_439438.1	similar to PID:1685099
NP_439439.2	similar to PID:1679866
NP_439440.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
NP_439441.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
NP_439442.1	catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis
NP_439443.1	catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis
NP_439445.1	similar to PID:882706 GB:U00096 SP:Q46926 PID:1789176
NP_439446.2	similar to PID:882705 GB:U00096 PID:1789175
NP_439447.2	similar to SP:P29769
NP_439448.1	similar to SP:P33372 PID:405872 GB:U00096 PID:1788463
NP_439449.1	similar to SP:P33373 PID:405873 GB:U00096 PID:1788464
NP_439451.1	Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth
NP_439452.1	similar to PID:1513236
NP_439453.2	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_439454.2	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
NP_439455.1	Regulates rRNA biosynthesis by transcriptional antitermination
NP_439456.1	similar to GB:U00096 SP:P77785 PID:1773101 PID:1786619 PID:2329840
NP_439457.1	similar to GB:U00096 PID:1773102 PID:1786620 PID:2329841
NP_439458.1	similar to GB:U00096 SP:P75693 PID:1657525 PID:1786522
NP_439459.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
NP_439460.1	similar to SP:P37910 GB:U00096 PID:1788568
NP_439462.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
NP_439463.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
NP_439464.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
NP_439465.1	similar to GB:M14031 SP:P23898 PID:145446 GB:U00096 PID:1742788
NP_439468.1	similar to GB:U00096 SP:P39173 PID:1736408 PID:1742898 PID:1788080
NP_439469.1	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
NP_439471.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
NP_439472.1	similar to SP:P08394 GB:X04581 GB:X04582 PID:42682 PID:763090
NP_439473.1	similar to SP:P04993 GB:X04581 GB:X04582 PID:42683 PID:42691
NP_439474.1	similar to SP:P45569 GB:U00096 PID:1787190
NP_439475.1	similar to GB:D00863 SP:P36772 PID:402504
NP_439476.1	catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP
NP_439479.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
NP_439482.1	penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains
NP_439483.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NP_439484.1	contains  RNA-binding domains; monomeric; similar to SP:P42550 PID:606118 GB:U00096 PID:1789570
NP_439485.1	Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit
NP_439486.1	similar to GB:M83138 SP:P28691 GB:U01376 PID:146028 PID:606116
NP_439487.1	similar to GB:L06494 SP:P26282 GB:U01376 GB:X68776 GB:X68777
NP_439488.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NP_439489.1	similar to GB:U00096 PID:1788681
NP_439491.1	similar to PID:882689 GB:U00096 SP:Q46920 PID:1789158
NP_439494.1	similar to SP:P43672 GB:U00096 PID:1787182 PID:2251144
NP_439495.1	similar to PID:1142681
NP_439496.1	can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component
NP_439497.1	can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component
NP_439498.2	functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase
NP_439499.1	catalyzes the release of the N-terminal amino acid from a tripeptide
NP_439500.1	similar to PID:1652428
NP_439501.1	Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis
NP_439502.1	similar to GB:U00096 PID:1788178
NP_439503.1	proline permease; similar to GB:D32069 PID:509694 PID:913690
NP_439504.1	involved in the processing of the 5'end of 16S rRNA
NP_439505.1	catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_439506.1	similar to GB:U00096 PID:1787429
NP_439507.1	similar to GB:M32793 SP:P15977 PID:146715 PID:606351 GB:U00096
NP_439508.1	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain
NP_439509.1	similar to GB:J01616 SP:P15067 PID:146135 PID:606366 GB:U00096
NP_439510.1	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate
NP_439511.1	catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose
NP_439512.1	similar to GB:J03966 SP:P13031 GB:M22368 GB:X16931 PID:146146
NP_439513.1	forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm
NP_439514.1	catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme
NP_439515.1	similar to SP:P37641 PID:466658 GB:U00096 PID:1789938
NP_439516.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
NP_439517.1	similar to GB:U00096 PID:1742298 PID:1742303 PID:1787680
NP_439518.1	catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_439519.1	similar to SP:P31828 GB:X71917 PID:535004 GB:U00096 PID:1742451
NP_439520.1	similar to SP:P31827 GB:X71917 PID:311346 GB:U00096 PID:1787771
NP_439521.1	similar to GB:M17157 SP:P04952 SP:P08854 GB:M17158 GB:X04982
NP_439522.1	similar to GB:L05610 SP:P45573 PID:145087
NP_439523.1	TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs
NP_439524.2	acts with MukB and MukE to condense the chromosome and allow for segregation during cell division
NP_439525.1	acts with MukB and MukF to condense the chromosome and allow for segregation during cell division
NP_439526.1	SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects
NP_439529.1	Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
NP_439530.1	similar to SP:P08400 GB:X04704 PID:581188 GB:U00096 PID:1657596
NP_439531.1	similar to SP:P08402 GB:X04026 PID:42388 GB:U00096 PID:1657595
NP_439533.1	similar to GB:L10328 SP:P07654 GB:K01992 GB:X02723 PID:147258
NP_439534.1	similar to GB:L10328 SP:P07653 GB:K01992 GB:X02723 PID:147257
NP_439536.1	similar to SP:P23887 GB:X53513 PID:42898 GB:U00096 PID:1736567
NP_439537.1	similar to SP:P23887 GB:X53513 PID:42898 GB:U00096 PID:1736567
NP_439539.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
NP_439540.1	TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity
NP_439542.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
NP_439543.1	monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate
NP_439545.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
NP_439546.1	similar to GB:L15391 PID:1574226
NP_439547.1	similar to GB:L15391 PID:1574230
NP_439548.1	similar to PID:887850 GB:U00096 SP:Q46828 PID:1789267
NP_439550.1	binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB
NP_439551.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
NP_439553.1	similar to GB:U00096 PID:1787520
NP_439554.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors
NP_439559.1	similar to GB:L10330 PID:437700
NP_439562.1	similar to SP:Q38627 PID:522116
NP_439563.1	similar to SP:P21417 PID:1196685
NP_439573.1	similar to SP:P10487 GB:D90039 SP:P16470 GB:AB027308 GB:AB027308
NP_439574.1	Global transcription factor that controls the expression of over 100 target genes in response to anoxia
NP_439575.2	with UspC and UspD is involved in resistance to UV irradiation
NP_439577.1	glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate
NP_439578.1	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
NP_439579.1	similar to GB:U00096 PID:1787820
NP_439580.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
NP_439581.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
NP_439582.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
NP_439583.1	contains a C-type lectin fold; similar to prolyl-tRNA synthetases; similar to GB:L23802 SP:P36922 PID:388109
NP_439584.1	similar to SP:P24245 GB:U00096 PID:1651400 PID:1787107
NP_439585.2	similar to GB:U00096 PID:1788113
NP_439587.1	similar to PID:882688 GB:U00096 PID:882687
NP_439589.1	catalyzes the bidirectional exonucleolytic cleavage of DNA
NP_439590.1	similar to GB:D00694 SP:P22939 PID:216584 GB:U00096 PID:1773105
NP_439591.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
NP_439592.1	similar to GB:M69028 SP:P25663 GB:X05088 PID:147872 PID:42999
NP_439593.1	similar to SP:P31784 PID:241868
NP_439594.1	forms a direct contact with the tRNA during translation
NP_439595.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
NP_439596.1	MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor
NP_439597.1	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
NP_439598.1	similar to GB:U00096 PID:1787427
NP_439599.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
NP_439600.1	similar to GB:M21151 SP:P12281 PID:145539 GB:U00096 PID:1651376
NP_439601.1	ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase
NP_439602.1	highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein
NP_439604.1	similar to GB:AL009126
NP_439605.1	similar to SP:P45706 PID:870925 PID:1405449 GB:AL009126
NP_439606.1	this fusion consists of methionine sulfoxide A reductase at the N-terminus and B at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion
NP_439608.1	similar to PID:2367659
NP_439610.2	Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
NP_439611.1	similar to GB:U00096 SP:P77211 PID:1778487 PID:1786785
NP_439613.1	similar to GB:U00096 PID:1788681
NP_439614.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NP_439615.1	similar to GB:L06494 SP:P26282 GB:U01376 GB:X68776 GB:X68777
NP_439616.1	similar to GB:M83138 SP:P28691 GB:U01376 PID:146028 PID:606116
NP_439618.1	similar to SP:Q50614 PID:1483552
NP_439619.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
NP_439621.1	similar to GB:AE000511 SP:O05732 PID:2072456 PID:2314024
NP_439622.1	similar to GB:AE000511 SP:O05731 PID:2072455 PID:2314025
NP_439623.1	similar to GB:AE000511 PID:2314746
NP_439624.1	involved in molybdenum transport
NP_439625.1	similar to GB:AE000511 PID:2313950
NP_439627.1	similar to SP:Q37906 PID:403436
NP_439628.1	similar to SP:P06903
NP_439629.1	similar to SP:P07636 PID:15450 PID:15810 PID:215511 PID:215547
NP_439632.1	similar to SP:P03763 PID:15448 PID:215512 PID:215550
NP_439634.1	similar to SP:P06023 PID:15461 PID:215562
NP_439638.1	similar to PID:215574
NP_439646.1	similar to SP:Q06424 PID:288658
NP_439653.1	similar to bacteriophage Mu G-1 protein; SP:Q01261 PID:215535
NP_439654.1	similar to bacteriophage Mu I protein; similar to SP:Q01267 PID:215536
NP_439658.1	similar to PID:2353778
NP_439659.2	similar to PID:2353777
NP_439660.1	similar to PID:1834290
NP_439661.1	similar to bacteriophage Mu L protein; PID:1834291
NP_439662.1	similar to PID:1834292
NP_439663.1	similar to PID:1834293
NP_439665.1	similar to SP:P08557 PID:15105
NP_439669.1	similar to GB:U00096 PID:1787398
NP_439670.2	similar to GB:U00096 PID:1787399
NP_439674.1	similar to GB:AE000666
NP_439675.1	catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose
NP_439676.2	Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA
NP_439677.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
NP_439678.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
NP_439679.1	similar to GB:L10328 SP:P19933 GB:D00626 GB:X17499 PID:216541
NP_439680.1	similar to SP:P17116 GB:X15859 PID:42747 GB:U00096 PID:1651386
NP_439681.1	functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase
NP_439682.1	FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
NP_439686.1	similar to GB:M27280 SP:P14181 GB:M37912 PID:1574379
NP_439687.1	similar to GB:M27280 SP:P14182
NP_439688.1	similar to GB:M27280 SP:P14183
NP_439689.1	similar to GB:M27280 SP:P14184
NP_439690.1	similar to GB:M13359 SP:P08395 GB:U13772 GB:U13773 GB:U13774
NP_439691.1	similar to PID:2253239
NP_439692.1	similar to GB:U00096 SP:P75915 PID:1787272
NP_439693.1	similar to SP:Q64669 PID:595518
NP_439694.1	involved in the import of serine and threonine coupled with the import of sodium
NP_439696.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive
NP_439697.1	part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane
NP_439698.1	similar to GB:U00096 SP:P75957 PID:1787361
NP_439699.1	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
NP_439700.1	similar to GB:J04423 SP:P12999 PID:145427 PID:490221 GB:U00096
NP_439702.1	catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine
NP_439703.1	catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate
NP_439704.1	similar to GB:U00096 SP:P75956 PID:1787360
NP_439705.1	Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor
NP_439706.1	catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis
NP_439707.1	similar to SP:P20101 GB:X05552 PID:41872 PID:1008040 GB:U00096
NP_439708.1	similar to GB:D28567 SP:P37186 PID:466533 PID:968931 GB:U00096
NP_439710.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
NP_439712.1	similar to GB:U00096 PID:1788666
NP_439715.1	similar to bacteriophage Mu G-2 protein; SP:Q01261 PID:215535
NP_439719.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
NP_439720.1	unwinds double stranded DNA
NP_439721.1	converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer
NP_439722.2	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
NP_439724.1	similar to PID:595813
NP_439725.1	similar to GB:M18877 SP:P10325
NP_439728.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
NP_439729.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit
NP_439730.1	acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate
NP_439731.1	similar to GB:AE000511 PID:2314087
NP_439732.1	similar to GB:X07688 SP:P08936 GB:X57231 GB:X59940 GB:X67326
NP_439733.1	produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine
NP_439734.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
NP_439735.1	similar to SP:P45526 GB:U00096 PID:1787119
NP_439736.1	participates with LolB in the incorporation of lipoprotein into the outer membrane
NP_439738.2	mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system
NP_439739.2	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
NP_439740.1	similar to SP:P30871 GB:Z21844 PID:49399 GB:U00096 PID:1789434
NP_439745.1	similar to GB:AE000782
NP_439746.1	similar to PID:1814405
NP_439747.1	similar to SP:P39202 PID:1203798 GB:U00096 PID:1789435
NP_439748.1	catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases
NP_439749.1	Incorporates lipoproteins in the outer membrane after they are released by the LolA protein
NP_439750.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
NP_439751.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
NP_439752.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
NP_439753.1	Regulatory factor involved in maltose metabolism
NP_439754.1	NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones
NP_439755.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
NP_439756.1	similar to GB:M15273 SP:P04825 GB:M15676 GB:X04020 PID:147142
NP_439757.1	Catalyzes a step in the de novo purine nucleotide biosynthetic pathway
NP_439758.1	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
NP_439759.1	catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate
NP_439760.2	similar to GB:AE000666
NP_439763.1	catalyzes the ATP-dependent transport of cobalt
NP_439766.1	similar to GB:X57326 PID:48151
NP_439768.1	similar to SP:P46909 PID:971339 GB:AL009126
NP_439769.1	similar to PID:2407234
NP_439770.1	similar to SP:P39436 PID:606172 GB:U00096 PID:1789628
NP_439771.2	similar to GB:M68934 SP:P09548 GB:X02743 PID:146363 GB:U00096
NP_439772.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
NP_439775.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
NP_439776.2	catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway
NP_439777.1	binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers
NP_439778.1	catalyzes the formation of oxaloacetate from phosphoenolpyruvate
NP_439779.1	similar to GB:U00096 PID:1787581
NP_439780.1	similar to SP:P36634 GB:X52093 GB:X74212 PID:414208
NP_439781.1	similar to SP:P36668 GB:X52093 GB:X74212 PID:414209
NP_439782.1	similar to SP:P36669 GB:X74212 PID:414210
NP_439783.1	similar to SP:P36636 GB:X74212 PID:414211
NP_439784.1	similar to SP:P36637 GB:U08190 PID:470683 GB:U00096 PID:1279404
NP_439785.1	similar to SP:P33019 PID:405879 GB:U00096 PID:1788482
NP_439786.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
NP_439787.1	catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate
NP_439788.1	Catalyzes the formation of (d)CDP from ATP and (d)CMP
NP_439789.1	with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate
NP_439790.2	with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate
NP_439791.1	component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent
NP_439793.1	nucleotide sequence similar to HI0220
NP_439794.1	similar to GB:U00096 SP:P77685 PID:1498150 PID:1736840 PID:1788501
NP_439795.2	similar to Zn-dependent protease; this region contains an authentic frame shift and is not the result of a sequencing artifact; similar to SP:P46473 PID:606183 GB:U00096 PID:1732437 PID:1789640
NP_439796.1	similar to SP:P45528 PID:606086 GB:U00096 PID:1789535
NP_439797.1	similar to PID:1353671
NP_439798.1	similar to SP:P45465 PID:606088 GB:U00096 PID:1789538
NP_439799.1	similar to SP:P45466 PID:606089 GB:U00096 PID:1789539
NP_439800.1	similar to SP:P45467 PID:606090 GB:U00096 PID:1789540
NP_439801.2	Catalyzes the rate-limiting step in dNTP synthesis
NP_439802.1	B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA
NP_439803.1	similar to GB:J01619 SP:P07016 GB:X00664 PID:146202 PID:43022
NP_439804.2	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide
NP_439805.1	similar to GB:U00096 SP:P75849 PID:1787158
NP_439806.2	similar to GB:U00089 SP:P78005 PID:1673805
NP_439809.1	similar to SP:P22525 GB:X57550 PID:42044 GB:U00096 PID:1787155
NP_439810.1	Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3
NP_439812.1	affects solute and DNA transport through an unknown mechanism
NP_439813.1	similar to GB:U00096 PID:1736474 PID:1736480 PID:1788137
NP_439814.1	similar to GB:U00096 PID:1736475 PID:1736481 PID:1788138
NP_439815.1	similar to GB:X70420 SP:P30749 PID:42012 GB:U00096 PID:1787003
NP_439816.1	catalyzes the conversion of molybdopterin precursor Z into molybdopterin
NP_439817.1	MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis
NP_439818.1	together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z
NP_439819.1	Involved in anaerobic NO protection and iron metabolism
NP_439820.1	similar to GB:L19929 SP:P42502 PID:455424
NP_439821.1	forms homotetramers; similar to SP:P45396 PID:606137 GB:U00096 PID:2367202
NP_439822.1	similar to GB:U00096 PID:1787194
NP_439823.1	similar to GB:U00096 PID:1787198
NP_439824.1	SohB; periplasmic protein; member of the peptidase S49 family
NP_439825.1	similar to rnfA/rnfE proteins; similar to GB:U00096 PID:1787914
NP_439826.1	part of membrane-bound complex thought to be involved in electron transport to nitrogen
NP_439827.1	part of membrane-bound complex thought to be involved in electron transport to nitrogen
NP_439828.1	RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents
NP_439829.1	part of membrane-bound complex hought to be involved in electron transport to nitrogen
NP_439830.1	in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase
NP_439831.1	similar to GB:J02857 SP:P20625 PID:146972 GB:U00096 PID:1742691
NP_439832.1	similar to GB:AL009126
NP_439833.1	Part of the ABC transporter complex modABC involved in molybdenum import
NP_439834.1	part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE
NP_439835.1	similar to GB:L34009 SP:P37329 PID:504498 PID:973214 PID:1147817
NP_439836.1	similar to PID:1002825 SP:P46930 GB:U00096 PID:1147816 PID:1786976
NP_439837.2	similar to PID:600434 SP:Q46635
NP_439838.1	similar to PID:1944156
NP_439839.1	similar to GB:U05670
NP_439840.1	similar to PID:633695
NP_439841.1	similar to PID:1546004
NP_439842.2	similar to GB:AE000666
NP_439843.1	similar to PID:1652989
NP_439844.1	catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
NP_439845.1	similar to GB:U14003 SP:P39341 PID:537104 GB:U00096 PID:1790713
NP_439846.1	similar to GB:U14003 SP:P39340 PID:537103 GB:U00096 PID:1790712
NP_439847.1	catalyzes the removal of N-terminal amino acids preferably leucine from various peptides
NP_439848.2	similar to SP:P17447 GB:X52905 PID:48716 GB:U00096 PID:1657512
NP_439849.1	similar to SP:P40719 PID:882556 GB:U00096 PID:1789403
NP_439850.1	similar to PID:882555 SP:P52076 GB:U00096 PID:1789402
NP_439851.1	similar to PID:882554 SP:P52083 GB:U00096 PID:1789401
NP_439853.1	functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose
NP_439854.1	Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system
NP_439855.1	similar to SP:P07006 PID:153936 PID:47845
NP_439856.1	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity
NP_439857.1	3'-5' exoribonuclease specific for small oligoribonuclotides
NP_439858.1	rfe; similar to GB:M87049 SP:P24235 GB:M76129 PID:147578 PID:148187
NP_439860.1	similar to GB:M96431 SP:P27249 PID:146155 PID:49393 PID:473822
NP_439861.2	similar to GB:U09558 PID:495495
NP_439862.2	similar to SP:P19769 GB:X07037 PID:581111 PID:912474 GB:U00096
NP_439863.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn
NP_439864.1	essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors
NP_439865.2	similar to SP:P45567 GB:U00096 PID:1786310
NP_439866.1	similar to GB:D26562 SP:P02919 GB:M12486 GB:X02163 PID:145948
NP_439867.2	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
NP_439868.1	catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis
NP_439869.1	similar to SP:P42964 PID:707085 PID:1805475 GB:AL009126
NP_439871.1	similar to GB:U00096 SP:P75745 PID:1786930
NP_439872.1	similar to GB:U00096 SP:P75744 PID:1786929
NP_439875.1	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NP_439876.2	acyl-carrier-protein reductase; similar to GB:M97219 SP:P29132 GB:X78733 PID:145851 PID:587106
NP_439877.1	stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein
NP_439879.1	similar to GB:AL009126
NP_439880.1	similar to GB:AL009126
NP_439881.1	similar to GB:J04155 SP:P19797 GB:M37630 PID:1790262
NP_439882.1	flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration
NP_439883.1	converts L-glutamate to D-glutamate, a component of peptidoglycan
NP_439884.1	catalyzes branch migration in Holliday junction intermediates
NP_439885.2	similar to GB:L10328 SP:P17580 GB:M24503 PID:290500 PID:551840
NP_439886.1	promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NP_439887.1	Essential for recycling GMP and indirectly, cGMP