-- dump date 20140619_105402 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001783356.1 170717207 6108903 279..1646 1 NC_010519.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1646 dnaA 6108903 dnaA Haemophilus somnus 2336 chromosomal replication initiation protein YP_001783356.1 279 D 228400 CDS YP_001783357.1 170718298 6106839 1658..2758 1 NC_010519.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2758 6106839 HSM_0002 Haemophilus somnus 2336 DNA polymerase III subunit beta YP_001783357.1 1658 D 228400 CDS YP_001783358.1 170718431 6107940 2762..3838 1 NC_010519.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 3838 recF 6107940 recF Haemophilus somnus 2336 recombination protein F YP_001783358.1 2762 D 228400 CDS YP_001783359.1 170718540 6108072 complement(3895..4539) 1 NC_010519.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 4539 6108072 HSM_0004 Haemophilus somnus 2336 cAMP-regulatory protein YP_001783359.1 3895 R 228400 CDS YP_001783360.1 170718646 6108182 complement(4552..4776) 1 NC_010519.1 PFAM: protein of unknown function UPF0270; KEGG: hso:HS_0140 hypothetical protein; hypothetical protein 4776 6108182 HSM_0005 Haemophilus somnus 2336 hypothetical protein YP_001783360.1 4552 R 228400 CDS YP_001783361.1 170718753 6108290 complement(4811..5470) 1 NC_010519.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 5470 slmA 6108290 slmA Haemophilus somnus 2336 nucleoid occlusion protein YP_001783361.1 4811 R 228400 CDS YP_001783362.1 170718862 6108399 complement(5470..5925) 1 NC_010519.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 5925 dut 6108399 dut Haemophilus somnus 2336 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_001783362.1 5470 R 228400 CDS YP_001783363.1 170718971 6108509 complement(5922..7148) 1 NC_010519.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 7148 6108509 HSM_0008 Haemophilus somnus 2336 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_001783363.1 5922 R 228400 CDS YP_001783364.1 170719078 6108619 7321..7989 1 NC_010519.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 7989 radC 6108619 radC Haemophilus somnus 2336 DNA repair protein RadC YP_001783364.1 7321 D 228400 CDS YP_001783365.1 170717208 6108728 8210..8446 1 NC_010519.1 required for 70S ribosome assembly; 50S ribosomal protein L28 8446 rpmB 6108728 rpmB Haemophilus somnus 2336 50S ribosomal protein L28 YP_001783365.1 8210 D 228400 CDS YP_001783366.1 170717317 6106840 8458..8628 1 NC_010519.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 8628 rpmG 6106840 rpmG Haemophilus somnus 2336 50S ribosomal protein L33 YP_001783366.1 8458 D 228400 CDS YP_001783367.1 170717422 6106950 8734..9546 1 NC_010519.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 9546 6106950 HSM_0012 Haemophilus somnus 2336 formamidopyrimidine-DNA glycosylase YP_001783367.1 8734 D 228400 CDS YP_001783368.1 170717531 6107058 9638..11314 1 NC_010519.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 11314 6107058 HSM_0013 Haemophilus somnus 2336 acetolactate synthase 2 catalytic subunit YP_001783368.1 9638 D 228400 CDS YP_001783369.1 170717640 6107168 11318..11536 1 NC_010519.1 KEGG: hso:HS_0148 acetohydroxy acid synthase II, small subunit; acetolactate synthase 2 regulatory subunit 11536 ilvM 6107168 ilvM Haemophilus somnus 2336 acetolactate synthase 2 regulatory subunit YP_001783369.1 11318 D 228400 CDS YP_001783370.1 170717751 6107278 11602..12264 1 NC_010519.1 PFAM: MOSC domain containing protein; KEGG: hso:HS_0149 hypothetical protein; MOSC domain-containing protein 12264 6107278 HSM_0015 Haemophilus somnus 2336 MOSC domain-containing protein YP_001783370.1 11602 D 228400 CDS YP_001783371.1 170717862 6107389 12384..12887 1 NC_010519.1 PFAM: chorismate lyase; KEGG: hso:HS_0150 4-hydroxybenzoate synthetase (chorismate--pyruvate lyase); chorismate lyase 12887 6107389 HSM_0016 Haemophilus somnus 2336 chorismate lyase YP_001783371.1 12384 D 228400 CDS YP_001783372.1 170717973 6107500 12891..15305 1 NC_010519.1 KEGG: hso:HS_0151 exoribonuclease II (ribonuclease R); TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; ribonuclease B OB region domain; ribonuclease R winged-helix domain protein; SMART: Cold shock protein; ribonuclease R 15305 6107500 HSM_0017 Haemophilus somnus 2336 ribonuclease R YP_001783372.1 12891 D 228400 CDS YP_001783373.1 170718084 6107611 15312..16049 1 NC_010519.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 16049 6107611 HSM_0018 Haemophilus somnus 2336 23S rRNA (guanosine-2'-O-)-methyltransferase YP_001783373.1 15312 D 228400 CDS YP_001783374.1 170718188 6107722 complement(16190..16516) 1 NC_010519.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: hso:HS_0153 conserved hypothetical protein, with TPR repeat (tetratrico peptide repeat); Sel1 domain-containing protein 16516 6107722 HSM_0019 Haemophilus somnus 2336 Sel1 domain-containing protein YP_001783374.1 16190 R 228400 CDS YP_001783375.1 170718299 6107830 complement(16560..17357) 1 NC_010519.1 catalyzes the O-acetylation of serine; serine acetyltransferase 17357 cysE 6107830 cysE Haemophilus somnus 2336 serine acetyltransferase YP_001783375.1 16560 R 228400 CDS YP_001783376.1 170718332 6107941 complement(17359..18522) 1 NC_010519.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 18522 gpsA 6107941 gpsA Haemophilus somnus 2336 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_001783376.1 17359 R 228400 CDS YP_001783377.1 170718343 6107973 complement(18437..18952) 1 NC_010519.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 18952 6107973 HSM_0022 Haemophilus somnus 2336 preprotein translocase subunit SecB YP_001783377.1 18437 R 228400 CDS YP_001783378.1 170718354 6107984 complement(18963..19409) 1 NC_010519.1 PFAM: rhodanese; KEGG: hso:HS_0157 conserved hypothetical protein, with rhodanese-like domain; rhodanese 19409 6107984 HSM_0023 Haemophilus somnus 2336 rhodanese YP_001783378.1 18963 R 228400 CDS YP_001783379.1 170718365 6107995 19652..20962 1 NC_010519.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 20962 6107995 HSM_0024 Haemophilus somnus 2336 anaerobic C4-dicarboxylate transporter YP_001783379.1 19652 D 228400 CDS YP_001783380.1 170718376 6108006 complement(21035..21895) 1 NC_010519.1 catalyzes the conversion of 4-hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 21895 ubiA 6108006 ubiA Haemophilus somnus 2336 4-hydroxybenzoate octaprenyltransferase YP_001783380.1 21035 R 228400 CDS YP_001783381.1 170718387 6108017 21934..22356 1 NC_010519.1 PFAM: rhodanese; KEGG: hso:HS_0160 thiosulfate sulfurtransferase; rhodanese 22356 6108017 HSM_0026 Haemophilus somnus 2336 rhodanese YP_001783381.1 21934 D 228400 CDS YP_001783382.1 170718398 6108028 complement(22380..22694) 1 NC_010519.1 KEGG: hso:HS_0161 hypothetical protein; hypothetical protein 22694 6108028 HSM_0027 Haemophilus somnus 2336 hypothetical protein YP_001783382.1 22380 R 228400 CDS YP_001783383.1 170718409 6108039 22738..23601 1 NC_010519.1 PFAM: rhomboid family protein; KEGG: hso:HS_0162 GlpG protein, rhomboid family; rhomboid family protein 23601 6108039 HSM_0028 Haemophilus somnus 2336 rhomboid family protein YP_001783383.1 22738 D 228400 CDS YP_001783384.1 170718420 6108050 23818..24342 1 NC_010519.1 PFAM: protein of unknown function DUF177; KEGG: hso:HS_0163 conserved hypothetical protein; hypothetical protein 24342 6108050 HSM_0029 Haemophilus somnus 2336 hypothetical protein YP_001783384.1 23818 D 228400 CDS YP_001783385.1 170718432 6108061 24360..24530 1 NC_010519.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 24530 rpmF 6108061 rpmF Haemophilus somnus 2336 50S ribosomal protein L32 YP_001783385.1 24360 D 228400 CDS YP_001783386.1 170718443 6108073 24651..24929 1 NC_010519.1 KEGG: hso:HS_0164 fatty acid/phospholipid synthesis protein; fatty acid/phospholipid synthesis protein 24929 6108073 HSM_0031 Haemophilus somnus 2336 fatty acid/phospholipid synthesis protein YP_001783386.1 24651 D 228400 CDS YP_001783387.1 170718452 6108084 24982..25932 1 NC_010519.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 25932 6108084 HSM_0032 Haemophilus somnus 2336 3-oxoacyl-ACP synthase YP_001783387.1 24982 D 228400 CDS YP_001783388.1 170718463 6108094 25976..26914 1 NC_010519.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase; KEGG: hso:HS_0166 [acyl-carrier protein] S-malonyltransferase; malonyl CoA-acyl carrier protein transacylase 26914 6108094 HSM_0033 Haemophilus somnus 2336 malonyl CoA-acyl carrier protein transacylase YP_001783388.1 25976 D 228400 CDS YP_001783389.1 170718474 6108105 26968..27693 1 NC_010519.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 27693 fabG 6108105 fabG Haemophilus somnus 2336 3-ketoacyl-ACP reductase YP_001783389.1 26968 D 228400 CDS YP_001783390.1 170718485 6108116 27948..28178 1 NC_010519.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 28178 acpP 6108116 acpP Haemophilus somnus 2336 acyl carrier protein YP_001783390.1 27948 D 228400 CDS YP_001783391.1 170718496 6108127 28327..28755 1 NC_010519.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 28755 rplK 6108127 rplK Haemophilus somnus 2336 50S ribosomal protein L11 YP_001783391.1 28327 D 228400 CDS YP_001783392.1 170718507 6108138 28760..29449 1 NC_010519.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 29449 rplA 6108138 rplA Haemophilus somnus 2336 50S ribosomal protein L1 YP_001783392.1 28760 D 228400 CDS YP_001783393.1 170718518 6108149 29733..30224 1 NC_010519.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 30224 rplJ 6108149 rplJ Haemophilus somnus 2336 50S ribosomal protein L10 YP_001783393.1 29733 D 228400 CDS YP_001783394.1 170718529 6108160 30276..30644 1 NC_010519.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 30644 rplL 6108160 rplL Haemophilus somnus 2336 50S ribosomal protein L7/L12 YP_001783394.1 30276 D 228400 CDS YP_001783395.1 170718541 6108171 complement(30884..32146) 1 NC_010519.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 32146 rho 6108171 rho Haemophilus somnus 2336 transcription termination factor Rho YP_001783395.1 30884 R 228400 CDS YP_001783396.1 170718552 6108183 32341..33600 1 NC_010519.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 33600 6108183 HSM_0041 Haemophilus somnus 2336 ATP-dependent RNA helicase RhlB YP_001783396.1 32341 D 228400 CDS YP_001783397.1 170718563 6108194 33714..34400 1 NC_010519.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 34400 6108194 HSM_0042 Haemophilus somnus 2336 ribulose-phosphate 3-epimerase YP_001783397.1 33714 D 228400 CDS YP_001783398.1 170718574 6108205 34397..35071 1 NC_010519.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 35071 6108205 HSM_0043 Haemophilus somnus 2336 phosphoglycolate phosphatase YP_001783398.1 34397 D 228400 CDS YP_001783399.1 170718585 6108216 35081..36082 1 NC_010519.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 36082 6108216 HSM_0044 Haemophilus somnus 2336 tryptophanyl-tRNA synthetase YP_001783399.1 35081 D 228400 CDS YP_001783400.1 170718593 6108227 complement(36303..36686) 1 NC_010519.1 KEGG: hso:HS_0178 hypothetical protein; hypothetical protein 36686 6108227 HSM_0045 Haemophilus somnus 2336 hypothetical protein YP_001783400.1 36303 R 228400 CDS YP_001783401.1 170718604 6108236 36796..37398 1 NC_010519.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; beta-phosphoglucomutase family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hso:HS_0179 phosphatase; beta-phosphoglucomutase family hydrolase 37398 6108236 HSM_0046 Haemophilus somnus 2336 beta-phosphoglucomutase family hydrolase YP_001783401.1 36796 D 228400 CDS YP_001783402.1 170718615 6108247 complement(37776..40529) 1 NC_010519.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0181 TonB-dependent outer membrane receptor; TonB-dependent receptor 40529 6108247 HSM_0047 Haemophilus somnus 2336 TonB-dependent receptor YP_001783402.1 37776 R 228400 CDS YP_001783403.1 170718626 6108258 complement(40762..41379) 1 NC_010519.1 PFAM: protein of unknown function UPF0126; KEGG: hso:HS_0182 hypothetical protein; hypothetical protein 41379 6108258 HSM_0048 Haemophilus somnus 2336 hypothetical protein YP_001783403.1 40762 R 228400 CDS YP_001783404.1 170718637 6108269 41621..43156 1 NC_010519.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 43156 6108269 HSM_0049 Haemophilus somnus 2336 threonine dehydratase YP_001783404.1 41621 D 228400 CDS YP_001783405.1 170718647 6108280 complement(43200..44144) 1 NC_010519.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 44144 ispH 6108280 ispH Haemophilus somnus 2336 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_001783405.1 43200 R 228400 CDS YP_001783406.1 170718658 6108291 complement(44144..44641) 1 NC_010519.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 44641 lspA 6108291 lspA Haemophilus somnus 2336 lipoprotein signal peptidase YP_001783406.1 44144 R 228400 CDS YP_001783407.1 170718669 6108302 45025..45258 1 NC_010519.1 KEGG: hso:HS_1548 outer membrane protein P1; outer membrane protein P1 45258 6108302 HSM_0052 Haemophilus somnus 2336 outer membrane protein P1 YP_001783407.1 45025 D 228400 CDS YP_001783408.1 170718680 6108313 45428..46420 1 NC_010519.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: hso:HS_1548 outer membrane protein P1; aromatic hydrocarbon degradation membrane protein 46420 6108313 HSM_0053 Haemophilus somnus 2336 aromatic hydrocarbon degradation membrane protein YP_001783408.1 45428 D 228400 CDS YP_001783409.1 170718689 6108324 complement(46567..49380) 1 NC_010519.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 49380 ileS 6108324 ileS Haemophilus somnus 2336 isoleucyl-tRNA synthetase YP_001783409.1 46567 R 228400 CDS YP_001783410.1 170718700 6108334 complement(49399..49947) 1 NC_010519.1 KEGG: hso:HS_0187 hypothetical protein; hypothetical protein 49947 6108334 HSM_0055 Haemophilus somnus 2336 hypothetical protein YP_001783410.1 49399 R 228400 CDS YP_001783411.1 170718711 6108345 complement(50045..50989) 1 NC_010519.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 50989 6108345 HSM_0056 Haemophilus somnus 2336 bifunctional riboflavin kinase/FMN adenylyltransferase YP_001783411.1 50045 R 228400 CDS YP_001783412.1 170718722 6108356 complement(51075..51560) 1 NC_010519.1 PFAM: dihydrofolate reductase region; KEGG: hso:HS_0189 dihydrofolate reductase; dihydrofolate reductase 51560 6108356 HSM_0057 Haemophilus somnus 2336 dihydrofolate reductase YP_001783412.1 51075 R 228400 CDS YP_001783413.1 170718731 6108367 complement(51613..52077) 1 NC_010519.1 KEGG: hso:HS_0190 hypothetical protein; hypothetical protein 52077 6108367 HSM_0058 Haemophilus somnus 2336 hypothetical protein YP_001783413.1 51613 R 228400 CDS YP_001783414.1 170718742 6108377 complement(52080..52868) 1 NC_010519.1 PFAM: protein of unknown function DUF1212; KEGG: hso:HS_0191 hypothetical protein; hypothetical protein 52868 6108377 HSM_0059 Haemophilus somnus 2336 hypothetical protein YP_001783414.1 52080 R 228400 CDS YP_001783415.1 170718754 6108388 53026..54138 1 NC_010519.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 54138 6108388 HSM_0060 Haemophilus somnus 2336 gamma-glutamyl kinase YP_001783415.1 53026 D 228400 CDS YP_001783416.1 170718763 6108400 complement(54299..54853) 1 NC_010519.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 54853 nusG 6108400 nusG Haemophilus somnus 2336 transcription antitermination protein NusG YP_001783416.1 54299 R 228400 CDS YP_001783417.1 170718774 6108410 complement(54855..55262) 1 NC_010519.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 55262 secE 6108410 secE Haemophilus somnus 2336 preprotein translocase subunit SecE YP_001783417.1 54855 R 228400 CDS YP_001783418.1 170718785 6108421 complement(55438..56622) 1 NC_010519.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 56622 6108421 HSM_0063 Haemophilus somnus 2336 elongation factor Tu YP_001783418.1 55438 R 228400 CDS YP_001783419.1 170718796 6108841 57327..58280 1 NC_010519.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 58280 6108841 HSM_0064 Haemophilus somnus 2336 pantothenate kinase YP_001783419.1 57327 D 228400 CDS YP_001783420.1 170718807 6108443 complement(58334..59542) 1 NC_010519.1 PFAM: sodium/glutamate symporter; KEGG: hso:HS_0197 sodium/glutamate symporter (glutamate permease); sodium/glutamate symporter 59542 6108443 HSM_0065 Haemophilus somnus 2336 sodium/glutamate symporter YP_001783420.1 58334 R 228400 CDS YP_001783421.1 170718818 6108454 complement(59724..63200) 1 NC_010519.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 63200 dnaE 6108454 dnaE Haemophilus somnus 2336 DNA polymerase III subunit alpha YP_001783421.1 59724 R 228400 CDS YP_001783422.1 170718829 6108465 complement(63366..65936) 1 NC_010519.1 PFAM: ATPase AAA; Clp domain protein; ATPase AAA; ATPase AAA-2 domain protein; SMART: ATPase AAA; KEGG: hso:HS_0199 ATP-dependent Clp protease subunit B; ATPase 65936 6108465 HSM_0067 Haemophilus somnus 2336 ATPase YP_001783422.1 63366 R 228400 CDS YP_001783423.1 170718840 6108476 complement(66120..66581) 1 NC_010519.1 PFAM: protein of unknown function DUF606; KEGG: hso:HS_0200 hypothetical protein; hypothetical protein 66581 6108476 HSM_0068 Haemophilus somnus 2336 hypothetical protein YP_001783423.1 66120 R 228400 CDS YP_001783424.1 170718851 6108487 66765..67022 1 NC_010519.1 catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide; oxaloacetate decarboxylase subunit gamma 67022 6108487 HSM_0069 Haemophilus somnus 2336 oxaloacetate decarboxylase subunit gamma YP_001783424.1 66765 D 228400 CDS YP_001783425.1 170718863 6108498 67035..68834 1 NC_010519.1 catalyzes the formation of pyruvate from oxaloacetate; oxaloacetate decarboxylase 68834 6108498 HSM_0070 Haemophilus somnus 2336 oxaloacetate decarboxylase YP_001783425.1 67035 D 228400 CDS YP_001783426.1 170718874 6108510 68847..70151 1 NC_010519.1 TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase subunit beta; KEGG: hso:HS_0203 oxaloacetate decarboxylase subunit beta; sodium ion-translocating decarboxylase subunit beta 70151 6108510 HSM_0071 Haemophilus somnus 2336 sodium ion-translocating decarboxylase subunit beta YP_001783426.1 68847 D 228400 CDS YP_001783427.1 170718885 6108521 complement(70224..71177) 1 NC_010519.1 TIGRFAM: transaldolase; PFAM: transaldolase; KEGG: hso:HS_0204 transaldolase; transaldolase B 71177 6108521 HSM_0072 Haemophilus somnus 2336 transaldolase B YP_001783427.1 70224 R 228400 CDS YP_001783428.1 170718896 6108532 71365..73710 1 NC_010519.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 73710 6108532 HSM_0073 Haemophilus somnus 2336 organic solvent tolerance protein YP_001783428.1 71365 D 228400 CDS YP_001783429.1 170718907 6108543 complement(73787..74866) 1 NC_010519.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 74866 6108543 HSM_0074 Haemophilus somnus 2336 fructose-bisphosphate aldolase YP_001783429.1 73787 R 228400 CDS YP_001783430.1 170718918 6108554 complement(74958..76127) 1 NC_010519.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 76127 pgk 6108554 pgk Haemophilus somnus 2336 phosphoglycerate kinase YP_001783430.1 74958 R 228400 CDS YP_001783431.1 170718929 6108565 76366..76626 1 NC_010519.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: hso:HS_0208 ferredoxin; 4Fe-4S ferredoxin 76626 6108565 HSM_0076 Haemophilus somnus 2336 4Fe-4S ferredoxin YP_001783431.1 76366 D 228400 CDS YP_001783432.1 170718940 6108576 complement(76675..88866) 1 NC_010519.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790 large adhesin; YadA domain-containing protein 88866 6108576 HSM_0077 Haemophilus somnus 2336 YadA domain-containing protein YP_001783432.1 76675 R 228400 CDS YP_001783433.1 170718951 6108587 complement(89145..89384) 1 NC_010519.1 KEGG: mmu:673901 hypothetical protein LOC673901; hypothetical protein 89384 6108587 HSM_0078 Haemophilus somnus 2336 hypothetical protein YP_001783433.1 89145 R 228400 CDS YP_001783434.1 170718962 6108598 complement(89441..90190) 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0210 polar amino acid ABC transporter ATP-binding protein; ABC transporter 90190 6108598 HSM_0079 Haemophilus somnus 2336 ABC transporter YP_001783434.1 89441 R 228400 CDS YP_001783435.1 170718972 6108609 complement(90204..90935) 1 NC_010519.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0211 amino acid ABC transporter permease; polar amino acid ABC transporter inner membrane subunit 90935 6108609 HSM_0080 Haemophilus somnus 2336 polar amino acid ABC transporter inner membrane subunit YP_001783435.1 90204 R 228400 CDS YP_001783436.1 170718983 6108620 complement(90910..91692) 1 NC_010519.1 PFAM: extracellular solute-binding protein family 3; KEGG: hso:HS_0212 amino acid ABC transporter substrate-binding; extracellular solute-binding protein 91692 6108620 HSM_0081 Haemophilus somnus 2336 extracellular solute-binding protein YP_001783436.1 90910 R 228400 CDS YP_001783437.1 170718994 6108631 92084..92572 1 NC_010519.1 KEGG: hso:HS_0218 Haemophilus-specific protein, uncharacterized; hypothetical protein 92572 6108631 HSM_0082 Haemophilus somnus 2336 hypothetical protein YP_001783437.1 92084 D 228400 CDS YP_001783438.1 170719005 6108642 complement(92735..94123) 1 NC_010519.1 TIGRFAM: anion transporter; PFAM: sodium/sulfate symporter; citrate transporter; KEGG: hso:HS_0219 conserved transporter NadC family; anion transporter 94123 6108642 HSM_0083 Haemophilus somnus 2336 anion transporter YP_001783438.1 92735 R 228400 CDS YP_001783439.1 170719012 6108653 complement(94307..94807) 1 NC_010519.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 94807 6108653 HSM_0084 Haemophilus somnus 2336 ribonuclease activity regulator protein RraA YP_001783439.1 94307 R 228400 CDS YP_001783440.1 170719023 6108662 complement(94854..95759) 1 NC_010519.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 95759 6108662 HSM_0085 Haemophilus somnus 2336 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001783440.1 94854 R 228400 CDS YP_001783441.1 170719034 6108673 95866..96588 1 NC_010519.1 PFAM: protein of unknown function UPF0066; KEGG: hso:HS_0222 hypothetical protein; hypothetical protein 96588 6108673 HSM_0086 Haemophilus somnus 2336 hypothetical protein YP_001783441.1 95866 D 228400 CDS YP_001783442.1 170719045 6108684 96870..98171 1 NC_010519.1 KEGG: dsy:DSY2532 hypothetical protein; hypothetical protein 98171 6108684 HSM_0087 Haemophilus somnus 2336 hypothetical protein YP_001783442.1 96870 D 228400 CDS YP_001783443.1 170719056 6108695 98140..98292 1 NC_010519.1 KEGG: hso:HS_0222 hypothetical protein; hypothetical protein 98292 6108695 HSM_0088 Haemophilus somnus 2336 hypothetical protein YP_001783443.1 98140 D 228400 CDS YP_001783444.1 170719067 6108706 98452..98871 1 NC_010519.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 98871 6108706 HSM_0089 Haemophilus somnus 2336 D-ribose pyranase YP_001783444.1 98452 D 228400 CDS YP_001783445.1 170719079 6108717 98892..100385 1 NC_010519.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; sugar ABC transporter ATP-binding protein 100385 6108717 HSM_0090 Haemophilus somnus 2336 sugar ABC transporter ATP-binding protein YP_001783445.1 98892 D 228400 CDS YP_001783446.1 170719090 6108729 100395..101354 1 NC_010519.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; sugar ABC transporter permease 101354 rbsC 6108729 rbsC Haemophilus somnus 2336 sugar ABC transporter permease YP_001783446.1 100395 D 228400 CDS YP_001783447.1 170719101 6108740 101383..102261 1 NC_010519.1 periplasmic substrate-binding component of the ATP-dependent ribose transporter; D-ribose transporter subunit RbsB 102261 6108740 HSM_0092 Haemophilus somnus 2336 D-ribose transporter subunit RbsB YP_001783447.1 101383 D 228400 CDS YP_001783448.1 170719112 6108751 102345..103298 1 NC_010519.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 103298 6108751 HSM_0093 Haemophilus somnus 2336 ribokinase YP_001783448.1 102345 D 228400 CDS YP_001783449.1 170719123 6108762 103319..104329 1 NC_010519.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_0226 ribose operon repressor; alanine racemase 104329 6108762 HSM_0094 Haemophilus somnus 2336 alanine racemase YP_001783449.1 103319 D 228400 CDS YP_001783450.1 170719134 6108773 complement(104358..104771) 1 NC_010519.1 PFAM: SmpA/OmlA domain protein; KEGG: hso:HS_0227 conserved small protein A; SmpA/OmlA domain-containing protein 104771 6108773 HSM_0095 Haemophilus somnus 2336 SmpA/OmlA domain-containing protein YP_001783450.1 104358 R 228400 CDS YP_001783451.1 170719145 6108784 complement(104839..105852) 1 NC_010519.1 PFAM: 37kDa nucleoid-associated protein; KEGG: hso:HS_0228 nucleoid-associated protein; nucleoid-associated protein NdpA 105852 6108784 HSM_0096 Haemophilus somnus 2336 nucleoid-associated protein NdpA YP_001783451.1 104839 R 228400 CDS YP_001783452.1 170719156 6108795 105970..106191 1 NC_010519.1 PFAM: protein of unknown function DUF1414; KEGG: hso:HS_0229 hypothetical protein; hypothetical protein 106191 6108795 HSM_0097 Haemophilus somnus 2336 hypothetical protein YP_001783452.1 105970 D 228400 CDS YP_001783453.1 170719165 6108806 106193..107935 1 NC_010519.1 PFAM: sulfatase; KEGG: hso:HS_0230 conserved hypothetical protein; sulfatase 107935 6108806 HSM_0098 Haemophilus somnus 2336 sulfatase YP_001783453.1 106193 D 228400 CDS YP_001783454.1 170719176 6108816 complement(108151..108867) 1 NC_010519.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 108867 6108816 HSM_0099 Haemophilus somnus 2336 sugar fermentation stimulation protein A YP_001783454.1 108151 R 228400 CDS YP_001783455.1 170717209 6108827 109076..110608 1 NC_010519.1 forms a tetramer composed of 2 subunit alphas and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 110608 pntA 6108827 pntA Haemophilus somnus 2336 NAD(P) transhydrogenase subunit alpha YP_001783455.1 109076 D 228400 CDS YP_001783456.1 170717220 6106841 110621..112081 1 NC_010519.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 subunit betas; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 112081 pntB 6106841 pntB Haemophilus somnus 2336 pyridine nucleotide transhydrogenase YP_001783456.1 110621 D 228400 CDS YP_001783457.1 170717231 6106852 112162..113811 1 NC_010519.1 PFAM: sulfatase; KEGG: hso:HS_0234 phosphoglycerol transferase; sulfatase 113811 6106852 HSM_0102 Haemophilus somnus 2336 sulfatase YP_001783457.1 112162 D 228400 CDS YP_001783458.1 170717242 6106863 complement(114180..115190) 1 NC_010519.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 115190 mglC 6106863 mglC Haemophilus somnus 2336 beta-methylgalactoside transporter inner membrane protein YP_001783458.1 114180 R 228400 CDS YP_001783459.1 170717253 6106874 complement(115207..116727) 1 NC_010519.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 116727 6106874 HSM_0104 Haemophilus somnus 2336 galactose/methyl galaxtoside transporter ATP-binding protein YP_001783459.1 115207 R 228400 CDS YP_001783460.1 170717264 6106885 complement(116780..117766) 1 NC_010519.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: pmu:PM1038 d-galactose binding periplasmic protein precursor; periplasmic binding protein/LacI transcriptional regulator 117766 6106885 HSM_0105 Haemophilus somnus 2336 periplasmic binding protein/LacI transcriptional regulator YP_001783460.1 116780 R 228400 CDS YP_001783461.1 170717295 6106907 119165..120214 1 NC_010519.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 120214 6106907 HSM_0108 Haemophilus somnus 2336 galactose-1-phosphate uridylyltransferase YP_001783461.1 119165 D 228400 CDS YP_001783462.1 170717306 6106928 120233..121399 1 NC_010519.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 121399 6106928 HSM_0109 Haemophilus somnus 2336 galactokinase YP_001783462.1 120233 D 228400 CDS YP_001783463.1 170717318 6106939 121393..122436 1 NC_010519.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 122436 galM 6106939 galM Haemophilus somnus 2336 aldose 1-epimerase YP_001783463.1 121393 D 228400 CDS YP_001783464.1 170717329 6106951 122612..123505 1 NC_010519.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: hso:HS_0237 magnesium and cobalt efflux protein; hypothetical protein 123505 6106951 HSM_0111 Haemophilus somnus 2336 hypothetical protein YP_001783464.1 122612 D 228400 CDS YP_001783465.1 170717340 6106962 123502..125034 1 NC_010519.1 transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 125034 lnt 6106962 lnt Haemophilus somnus 2336 apolipoprotein N-acyltransferase YP_001783465.1 123502 D 228400 CDS YP_001783466.1 170717351 6106973 complement(125042..125833) 1 NC_010519.1 PFAM: TatD-related deoxyribonuclease; KEGG: hso:HS_0239 deoxyribonuclease, TatD family; TatD-related deoxyribonuclease 125833 6106973 HSM_0113 Haemophilus somnus 2336 TatD-related deoxyribonuclease YP_001783466.1 125042 R 228400 CDS YP_001783467.1 170717362 6106984 complement(126026..126535) 1 NC_010519.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: hso:HS_0241 peptidylprolyl isomerase (peptidyl-prolyl cis-trans isomerase); cyclophilin type peptidyl-prolyl cis-trans isomerase 126535 6106984 HSM_0114 Haemophilus somnus 2336 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_001783467.1 126026 R 228400 CDS YP_001783468.1 170717373 6106995 126674..128053 1 NC_010519.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 128053 cysS 6106995 cysS Haemophilus somnus 2336 cysteinyl-tRNA synthetase YP_001783468.1 126674 D 228400 CDS YP_001783469.1 170717384 6107006 complement(128105..128848) 1 NC_010519.1 PFAM: protein of unknown function DUF208; KEGG: hso:HS_0243 hypothetical protein; hypothetical protein 128848 6107006 HSM_0116 Haemophilus somnus 2336 hypothetical protein YP_001783469.1 128105 R 228400 CDS YP_001783470.1 170717395 6107017 complement(128970..129962) 1 NC_010519.1 PFAM: polyprenyl synthetase; KEGG: hso:HS_0244 octaprenyl-diphosphate synthase; polyprenyl synthetase 129962 6107017 HSM_0117 Haemophilus somnus 2336 polyprenyl synthetase YP_001783470.1 128970 R 228400 CDS YP_001783471.1 170717403 6107028 130182..130493 1 NC_010519.1 PFAM: ribosomal protein L21; KEGG: hso:HS_0245 50S ribosomal protein L21; 50S ribosomal protein L21 130493 rplU 6107028 rplU Haemophilus somnus 2336 50S ribosomal protein L21 YP_001783471.1 130182 D 228400 CDS YP_001783472.1 170717413 6107038 130514..130771 1 NC_010519.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 130771 rpmA 6107038 rpmA Haemophilus somnus 2336 50S ribosomal protein L27 YP_001783472.1 130514 D 228400 CDS YP_001783473.1 170717423 6107048 130907..131827 1 NC_010519.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: hso:HS_0247 hypothetical protein; hypothetical protein 131827 6107048 HSM_0120 Haemophilus somnus 2336 hypothetical protein YP_001783473.1 130907 D 228400 CDS YP_001783474.1 170717434 6107059 131837..133015 1 NC_010519.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 133015 obgE 6107059 obgE Haemophilus somnus 2336 GTPase ObgE YP_001783474.1 131837 D 228400 CDS YP_001783475.1 170717445 6107070 complement(133257..133826) 1 NC_010519.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: hso:HS_0249 N-acetyl-anhydromuramyl-L-alanine amidase; N-acetyl-anhydromuranmyl-L-alanine amidase 133826 6107070 HSM_0122 Haemophilus somnus 2336 N-acetyl-anhydromuranmyl-L-alanine amidase YP_001783475.1 133257 R 228400 CDS YP_001783476.1 170717456 6107081 133949..134407 1 NC_010519.1 KEGG: hso:HS_0250 fimbrial subunit; fimbrial subunit 134407 6107081 HSM_0123 Haemophilus somnus 2336 fimbrial subunit YP_001783476.1 133949 D 228400 CDS YP_001783477.1 170717467 6107092 134553..135290 1 NC_010519.1 With ArtMQJI transports arginine across the inner membrane; arginine ABC transporter ATP-binding protein 135290 artP 6107092 artP Haemophilus somnus 2336 arginine ABC transporter ATP-binding protein YP_001783477.1 134553 D 228400 CDS YP_001783478.1 170717478 6107103 135308..136033 1 NC_010519.1 PFAM: extracellular solute-binding protein family 3; KEGG: hso:HS_0252 arginine ABC transporter substrate-binding protein; extracellular solute-binding protein 136033 6107103 HSM_0125 Haemophilus somnus 2336 extracellular solute-binding protein YP_001783478.1 135308 D 228400 CDS YP_001783479.1 170717489 6107114 136038..136709 1 NC_010519.1 with ArtPMJI transports arginine across the inner membrane; arginine ABC transporter permease 136709 6107114 HSM_0126 Haemophilus somnus 2336 arginine ABC transporter permease YP_001783479.1 136038 D 228400 CDS YP_001783480.1 170717498 6107125 136720..137403 1 NC_010519.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine ABC transporter permease 137403 artM 6107125 artM Haemophilus somnus 2336 arginine ABC transporter permease YP_001783480.1 136720 D 228400 CDS YP_001783481.1 170717509 6107135 complement(137509..137796) 1 NC_010519.1 KEGG: hso:HS_0255 hypothetical protein; hypothetical protein 137796 6107135 HSM_0128 Haemophilus somnus 2336 hypothetical protein YP_001783481.1 137509 R 228400 CDS YP_001783482.1 170717520 6107146 138256..139821 1 NC_010519.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: hso:HS_0256 cytochrome d ubiquinol oxidase subunit I; cytochrome bd ubiquinol oxidase subunit I 139821 6107146 HSM_0129 Haemophilus somnus 2336 cytochrome bd ubiquinol oxidase subunit I YP_001783482.1 138256 D 228400 CDS YP_001783483.1 170717532 6107157 139836..140972 1 NC_010519.1 TIGRFAM: cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: hso:HS_0257 cytochrome d ubiquinol oxidase subunit II; cytochrome d ubiquinol oxidase subunit II 140972 6107157 HSM_0130 Haemophilus somnus 2336 cytochrome d ubiquinol oxidase subunit II YP_001783483.1 139836 D 228400 CDS YP_001783484.1 170717543 6107169 141347..141772 1 NC_010519.1 TIGRFAM: Pol-Pal system-associated acyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: hso:HS_0258 thioesterase; Pol-Pal system-associated acyl-CoA thioesterase 141772 6107169 HSM_0131 Haemophilus somnus 2336 Pol-Pal system-associated acyl-CoA thioesterase YP_001783484.1 141347 D 228400 CDS YP_001783485.1 170717554 6107180 141769..142452 1 NC_010519.1 TIGRFAM: Tol-Pal system TolQ; PFAM: MotA/TolQ/ExbB proton channel; KEGG: hso:HS_0259 biopolymer transporter; Tol-Pal system protein TolQ 142452 6107180 HSM_0132 Haemophilus somnus 2336 Tol-Pal system protein TolQ YP_001783485.1 141769 D 228400 CDS YP_001783486.1 170717565 6107191 142520..142942 1 NC_010519.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 142942 6107191 HSM_0133 Haemophilus somnus 2336 colicin uptake protein TolR YP_001783486.1 142520 D 228400 CDS YP_001783487.1 170717576 6107202 142961..144016 1 NC_010519.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 144016 tolA 6107202 tolA Haemophilus somnus 2336 cell envelope integrity inner membrane protein TolA YP_001783487.1 142961 D 228400 CDS YP_001783488.1 170717585 6107213 144044..145348 1 NC_010519.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 145348 tolB 6107213 tolB Haemophilus somnus 2336 translocation protein TolB YP_001783488.1 144044 D 228400 CDS YP_001783489.1 170717596 6107223 145358..145813 1 NC_010519.1 TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: hso:HS_0263 peptidoglycan-associated outer membrane lipoprotein (outer membrane protein P6); peptidoglycan-associated lipoprotein 145813 6107223 HSM_0136 Haemophilus somnus 2336 peptidoglycan-associated lipoprotein YP_001783489.1 145358 D 228400 CDS YP_001783490.1 170717607 6108844 146488..147015 1 NC_010519.1 KEGG: hso:HS_0264 type II secretory pathway, pseudopilin; type II secretory pathway, pseudopilin 147015 6108844 HSM_0137 Haemophilus somnus 2336 type II secretory pathway, pseudopilin YP_001783490.1 146488 D 228400 CDS YP_001783491.1 170717618 6107245 147028..147741 1 NC_010519.1 KEGG: hso:HS_0265 hypothetical protein; hypothetical protein 147741 6107245 HSM_0138 Haemophilus somnus 2336 hypothetical protein YP_001783491.1 147028 D 228400 CDS YP_001783492.1 170717629 6107256 147744..148424 1 NC_010519.1 KEGG: hso:HS_0266 hypothetical protein; hypothetical protein 148424 6107256 HSM_0139 Haemophilus somnus 2336 hypothetical protein YP_001783492.1 147744 D 228400 CDS YP_001783493.1 170717641 6107267 148405..148722 1 NC_010519.1 KEGG: hso:HS_0267 hypothetical protein; hypothetical protein 148722 6107267 HSM_0140 Haemophilus somnus 2336 hypothetical protein YP_001783493.1 148405 D 228400 CDS YP_001783494.1 170717652 6107279 148775..152209 1 NC_010519.1 TIGRFAM: exodeoxyribonuclease V, subunit gamma; PFAM: exodeoxyribonuclease V RecC subunit; KEGG: hso:HS_0268 exodeoxyribonuclease V, subunit gamma; exodeoxyribonuclease V subunit gamma 152209 6107279 HSM_0141 Haemophilus somnus 2336 exodeoxyribonuclease V subunit gamma YP_001783494.1 148775 D 228400 CDS YP_001783495.1 170717663 6107290 152288..152902 1 NC_010519.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 152902 ruvA 6107290 ruvA Haemophilus somnus 2336 Holliday junction DNA helicase RuvA YP_001783495.1 152288 D 228400 CDS YP_001783496.1 170717674 6107301 152913..153920 1 NC_010519.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 153920 ruvB 6107301 ruvB Haemophilus somnus 2336 Holliday junction DNA helicase RuvB YP_001783496.1 152913 D 228400 CDS YP_001783497.1 170717685 6107312 complement(154034..155242) 1 NC_010519.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase; KEGG: hso:HS_0271 conserved hypothetical protein; hypothetical protein 155242 6107312 HSM_0144 Haemophilus somnus 2336 hypothetical protein YP_001783497.1 154034 R 228400 CDS YP_001783498.1 170717696 6107323 complement(155242..156207) 1 NC_010519.1 TIGRFAM: methyltransferase; PFAM: methyltransferase ; methyltransferase type 11; methyltransferase type 12; KEGG: hso:HS_0272 S-adenosylmethionine-dependent methyltransferase; methyltransferase 156207 6107323 HSM_0145 Haemophilus somnus 2336 methyltransferase YP_001783498.1 155242 R 228400 CDS YP_001783499.1 170717707 6107334 complement(156210..157724) 1 NC_010519.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na?? symporter; KEGG: hso:HS_0273 sodium/proline symporter; sodium/proline symporter 157724 6107334 HSM_0146 Haemophilus somnus 2336 sodium/proline symporter YP_001783499.1 156210 R 228400 CDS YP_001783500.1 170717718 6107345 157852..159330 1 NC_010519.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 159330 6107345 HSM_0147 Haemophilus somnus 2336 ribonuclease G YP_001783500.1 157852 D 228400 CDS YP_001783501.1 170717729 6107356 159385..160167 1 NC_010519.1 KEGG: hso:HS_0275 glycosyltransferase; glycosyltransferase 160167 6107356 HSM_0148 Haemophilus somnus 2336 glycosyltransferase YP_001783501.1 159385 D 228400 CDS YP_001783502.1 170717740 6107367 160305..161753 1 NC_010519.1 PFAM: peptidase U62 modulator of DNA gyrase; KEGG: hso:HS_0276 modulator of DNA gyrase; peptidase U62 modulator of DNA gyrase 161753 6107367 HSM_0149 Haemophilus somnus 2336 peptidase U62 modulator of DNA gyrase YP_001783502.1 160305 D 228400 CDS YP_001783503.1 170717752 6107378 161967..163415 1 NC_010519.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: hso:HS_0277 SAM-dependent methyltransferase; methyltransferase type 12 163415 6107378 HSM_0150 Haemophilus somnus 2336 methyltransferase type 12 YP_001783503.1 161967 D 228400 CDS YP_001783504.1 170717763 6107390 complement(163496..164302) 1 NC_010519.1 PFAM: inositol monophosphatase; KEGG: hso:HS_0278 inositol-1(or 4)-monophosphatase; inositol-phosphate phosphatase 164302 6107390 HSM_0151 Haemophilus somnus 2336 inositol-phosphate phosphatase YP_001783504.1 163496 R 228400 CDS YP_001783505.1 170717774 6107401 164474..165214 1 NC_010519.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: hso:HS_0279 tRNA/rRNA methyltransferase; RNA methyltransferase 165214 6107401 HSM_0152 Haemophilus somnus 2336 RNA methyltransferase YP_001783505.1 164474 D 228400 CDS YP_001783506.1 170717785 6107412 165268..165675 1 NC_010519.1 TIGRFAM: transcriptional regulator, Rrf2 family; iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074; KEGG: hso:HS_0280 transcriptional regulator; BadM/Rrf2 family transcriptional regulator 165675 6107412 HSM_0153 Haemophilus somnus 2336 BadM/Rrf2 family transcriptional regulator YP_001783506.1 165268 D 228400 CDS YP_001783507.1 170717796 6107423 165754..166968 1 NC_010519.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 166968 6107423 HSM_0154 Haemophilus somnus 2336 cysteine desulfurase YP_001783507.1 165754 D 228400 CDS YP_001783508.1 170717807 6107434 167045..167428 1 NC_010519.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: hso:HS_0282 iron-sulfur cofactor synthesis protein; scaffold protein 167428 6107434 HSM_0155 Haemophilus somnus 2336 scaffold protein YP_001783508.1 167045 D 228400 CDS YP_001783509.1 170717818 6107445 167594..167917 1 NC_010519.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; iron-sulfur cluster assembly protein IscA; PFAM: HesB/YadR/YfhF-family protein; KEGG: hso:HS_0283 HesB-family protein; iron-sulfur cluster assembly protein IscA 167917 6107445 HSM_0156 Haemophilus somnus 2336 iron-sulfur cluster assembly protein IscA YP_001783509.1 167594 D 228400 CDS YP_001783510.1 170717829 6107456 167930..168448 1 NC_010519.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 168448 hscB 6107456 hscB Haemophilus somnus 2336 co-chaperone HscB YP_001783510.1 167930 D 228400 CDS YP_001783511.1 170717840 6107467 168490..170340 1 NC_010519.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 170340 hscA 6107467 hscA Haemophilus somnus 2336 chaperone protein HscA YP_001783511.1 168490 D 228400 CDS YP_001783512.1 170717851 6107478 170352..170693 1 NC_010519.1 TIGRFAM: ferredoxin 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: hso:HS_0286 ferredoxin; 2Fe-2S type ferredoxin 170693 6107478 HSM_0159 Haemophilus somnus 2336 2Fe-2S type ferredoxin YP_001783512.1 170352 D 228400 CDS YP_001783513.1 170717863 6107489 170828..173101 1 NC_010519.1 Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; bifunctional glutamate--cysteine ligase/glutathione synthetase 173101 6107489 HSM_0160 Haemophilus somnus 2336 bifunctional glutamate--cysteine ligase/glutathione synthetase YP_001783513.1 170828 D 228400 CDS YP_001783514.1 170717874 6107501 complement(173270..173986) 1 NC_010519.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 173986 deoD 6107501 deoD Haemophilus somnus 2336 purine nucleoside phosphorylase YP_001783514.1 173270 R 228400 CDS YP_001783515.1 170717885 6107512 complement(174119..175378) 1 NC_010519.1 TIGRFAM: nucleoside transporter; PFAM: Na dependent nucleoside transporter; nucleoside recognition domain protein; Na dependent nucleoside transporter domain protein; KEGG: hso:HS_0289 transporter permease; nucleoside transporter 175378 6107512 HSM_0162 Haemophilus somnus 2336 nucleoside transporter YP_001783515.1 174119 R 228400 CDS YP_001783516.1 170717896 6107523 175554..176198 1 NC_010519.1 PFAM: protein of unknown function DUF161; KEGG: hso:HS_0290 hypothetical protein; hypothetical protein 176198 6107523 HSM_0163 Haemophilus somnus 2336 hypothetical protein YP_001783516.1 175554 D 228400 CDS YP_001783517.1 170717907 6107534 176275..177843 1 NC_010519.1 PFAM: glycosyl transferase family 2; KEGG: hhe:HH0773 hypothetical protein; glycosyl transferase family protein 177843 6107534 HSM_0164 Haemophilus somnus 2336 glycosyl transferase family protein YP_001783517.1 176275 D 228400 CDS YP_001783518.1 170717918 6107545 178024..178272 1 NC_010519.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 178272 rpsP 6107545 rpsP Haemophilus somnus 2336 30S ribosomal protein S16 YP_001783518.1 178024 D 228400 CDS YP_001783519.1 170717929 6107556 178299..178826 1 NC_010519.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 178826 rimM 6107556 rimM Haemophilus somnus 2336 16S rRNA-processing protein RimM YP_001783519.1 178299 D 228400 CDS YP_001783520.1 170717940 6107567 178880..179617 1 NC_010519.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 179617 trmD 6107567 trmD Haemophilus somnus 2336 tRNA (guanine-N(1)-)-methyltransferase YP_001783520.1 178880 D 228400 CDS YP_001783521.1 170717951 6107578 179653..180003 1 NC_010519.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 180003 rplS 6107578 rplS Haemophilus somnus 2336 50S ribosomal protein L19 YP_001783521.1 179653 D 228400 CDS YP_001783522.1 170717962 6107589 complement(180138..180956) 1 NC_010519.1 PFAM: esterase; KEGG: hso:HS_0297 hydrolase; esterase 180956 6107589 HSM_0169 Haemophilus somnus 2336 esterase YP_001783522.1 180138 R 228400 CDS YP_001783523.1 170717974 6107600 complement(180993..181994) 1 NC_010519.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_0298 gluconate utilization operon repressor; periplasmic binding protein/LacI transcriptional regulator 181994 6107600 HSM_0170 Haemophilus somnus 2336 periplasmic binding protein/LacI transcriptional regulator YP_001783523.1 180993 R 228400 CDS YP_001783524.1 170717985 6107612 complement(182003..183055) 1 NC_010519.1 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: hso:HS_0299 tRNA/rRNA methyltransferase; tRNA/rRNA methyltransferase SpoU 183055 6107612 HSM_0171 Haemophilus somnus 2336 tRNA/rRNA methyltransferase SpoU YP_001783524.1 182003 R 228400 CDS YP_001783525.1 170717996 6107623 183221..184588 1 NC_010519.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 184588 pssA 6107623 pssA Haemophilus somnus 2336 phosphatidylserine synthase YP_001783525.1 183221 D 228400 CDS YP_001783526.1 170718007 6107634 complement(184618..185328) 1 NC_010519.1 PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: hso:HS_0301 DNA polymerase III subunit epsilon; exonuclease RNase T and DNA polymerase III 185328 6107634 HSM_0173 Haemophilus somnus 2336 exonuclease RNase T and DNA polymerase III YP_001783526.1 184618 R 228400 CDS YP_001783527.1 170718018 6107645 complement(185325..187205) 1 NC_010519.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294 nucleotidyltransferase KEGG: hso:HS_0302 signal-transduction protein; hypothetical protein 187205 6107645 HSM_0174 Haemophilus somnus 2336 hypothetical protein YP_001783527.1 185325 R 228400 CDS YP_001783528.1 170718029 6107656 complement(187307..189217) 1 NC_010519.1 PFAM: PfkB domain protein; KEGG: hso:HS_0303 myo-inositol catabolism protein; ribokinase 189217 6107656 HSM_0175 Haemophilus somnus 2336 ribokinase YP_001783528.1 187307 R 228400 CDS YP_001783529.1 170718040 6107667 189460..190302 1 NC_010519.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: hso:HS_0304 transcriptional regulator; RpiR family transcriptional regulator 190302 6107667 HSM_0176 Haemophilus somnus 2336 RpiR family transcriptional regulator YP_001783529.1 189460 D 228400 CDS YP_001783530.1 170718051 6107678 complement(190339..191103) 1 NC_010519.1 PFAM: protein of unknown function DUF548; KEGG: hso:HS_0305 SAM-dependent methyltransferase; hypothetical protein 191103 6107678 HSM_0177 Haemophilus somnus 2336 hypothetical protein YP_001783530.1 190339 R 228400 CDS YP_001783531.1 170718062 6107689 complement(191079..192179) 1 NC_010519.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 192179 6107689 HSM_0178 Haemophilus somnus 2336 tRNA (uracil-5-)-methyltransferase YP_001783531.1 191079 R 228400 CDS YP_001783532.1 170718073 6107700 complement(192245..192574) 1 NC_010519.1 PFAM: protein of unknown function DUF413; KEGG: hso:HS_0307 hypothetical protein; hypothetical protein 192574 6107700 HSM_0179 Haemophilus somnus 2336 hypothetical protein YP_001783532.1 192245 R 228400 CDS YP_001783533.1 170718085 6107711 complement(192628..193236) 1 NC_010519.1 PFAM: DSBA oxidoreductase; KEGG: hso:HS_0308 protein disulfide-isomerase (thiol:disulfide interchange protein); DSBA oxidoreductase 193236 6107711 HSM_0180 Haemophilus somnus 2336 DSBA oxidoreductase YP_001783533.1 192628 R 228400 CDS YP_001783534.1 170718096 6107723 complement(193246..193512) 1 NC_010519.1 PFAM: protein of unknown function DUF1040; KEGG: hso:HS_0309 hypothetical protein; hypothetical protein 193512 6107723 HSM_0181 Haemophilus somnus 2336 hypothetical protein YP_001783534.1 193246 R 228400 CDS YP_001783535.1 170718107 6107734 193579..194166 1 NC_010519.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 194166 mobA 6107734 mobA Haemophilus somnus 2336 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_001783535.1 193579 D 228400 CDS YP_001783536.1 170718116 6107745 194285..196291 1 NC_010519.1 TIGRFAM: oligopeptide transporters, OPT superfamily; oligopeptide transporter OPT family; PFAM: oligopeptide transporter OPT superfamily protein; KEGG: hso:HS_0311 integral membrane protein; OPT family oligopeptide transporter 196291 6107745 HSM_0183 Haemophilus somnus 2336 OPT family oligopeptide transporter YP_001783536.1 194285 D 228400 CDS YP_001783537.1 170718127 6107755 complement(196413..197171) 1 NC_010519.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: hso:HS_0313 conserved hypothetical protein, with TPR repeat (tetratrico peptide repeat); Sel1 domain-containing protein 197171 6107755 HSM_0184 Haemophilus somnus 2336 Sel1 domain-containing protein YP_001783537.1 196413 R 228400 CDS YP_001783538.1 170718138 6107766 complement(197193..197456) 1 NC_010519.1 KEGG: hso:HS_0314 Haemophilus-specific protein, uncharacterized; hypothetical protein 197456 6107766 HSM_0185 Haemophilus somnus 2336 hypothetical protein YP_001783538.1 197193 R 228400 CDS YP_001783539.1 170718149 6107777 complement(197940..198902) 1 NC_010519.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 198902 6107777 HSM_0186 Haemophilus somnus 2336 lipoyl synthase YP_001783539.1 197940 R 228400 CDS YP_001783540.1 170718160 6107788 complement(198920..199576) 1 NC_010519.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system protein H; lipoate-protein ligase B 199576 lipB 6107788 lipB Haemophilus somnus 2336 lipoate-protein ligase B YP_001783540.1 198920 R 228400 CDS YP_001783541.1 170718169 6107799 complement(199585..199881) 1 NC_010519.1 PFAM: protein of unknown function DUF493; KEGG: hso:HS_0317 hypothetical protein; hypothetical protein 199881 6107799 HSM_0188 Haemophilus somnus 2336 hypothetical protein YP_001783541.1 199585 R 228400 CDS YP_001783542.1 170718199 6107819 complement(201211..201771) 1 NC_010519.1 TIGRFAM: lipoprotein A; PFAM: Rare lipoprotein A; KEGG: hso:HS_0319 lipoprotein A; lipoprotein A 201771 6107819 HSM_0191 Haemophilus somnus 2336 lipoprotein A YP_001783542.1 201211 R 228400 CDS YP_001783543.1 170718210 6107841 complement(201814..202929) 1 NC_010519.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: hso:HS_0320 rod shape-determining protein; rod shape-determining protein RodA 202929 6107841 HSM_0192 Haemophilus somnus 2336 rod shape-determining protein RodA YP_001783543.1 201814 R 228400 CDS YP_001783544.1 170718221 6107852 complement(202952..204856) 1 NC_010519.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: hso:HS_0321 cell elongation-specific transpeptidase; peptidoglycan glycosyltransferase 204856 6107852 HSM_0193 Haemophilus somnus 2336 peptidoglycan glycosyltransferase YP_001783544.1 202952 R 228400 CDS YP_001783545.1 170718232 6107863 complement(204873..205340) 1 NC_010519.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 205340 6107863 HSM_0194 Haemophilus somnus 2336 rRNA large subunit methyltransferase YP_001783545.1 204873 R 228400 CDS YP_001783546.1 170718243 6107874 complement(205360..205668) 1 NC_010519.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: hso:HS_0323 hypothetical protein; iojap family protein 205668 6107874 HSM_0195 Haemophilus somnus 2336 iojap family protein YP_001783546.1 205360 R 228400 CDS YP_001783547.1 170718254 6107885 complement(206021..206863) 1 NC_010519.1 PFAM: ABC transporter; KEGG: hso:HS_0325 chelated iron ABC transporter permease; ABC transporter 206863 6107885 HSM_0196 Haemophilus somnus 2336 ABC transporter YP_001783547.1 206021 R 228400 CDS YP_001783548.1 170718265 6107896 complement(206856..207746) 1 NC_010519.1 PFAM: transporter permease; ABC-3 protein; KEGG: hso:HS_0326 chelated iron ABC transporter permease; ABC transporter 207746 6107896 HSM_0197 Haemophilus somnus 2336 ABC transporter YP_001783548.1 206856 R 228400 CDS YP_001783549.1 170718276 6107907 complement(207751..208509) 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0327 iron ABC transporter ATP-binding protein; ABC transporter 208509 6107907 HSM_0198 Haemophilus somnus 2336 ABC transporter YP_001783549.1 207751 R 228400 CDS YP_001783550.1 170718287 6107918 complement(208519..209400) 1 NC_010519.1 PFAM: periplasmic solute binding protein; KEGG: hso:HS_0328 chelated iron ABC transporter periplasmic-binding protein; periplasmic solute binding protein 209400 6107918 HSM_0199 Haemophilus somnus 2336 periplasmic solute binding protein YP_001783550.1 208519 R 228400 CDS YP_001783551.1 170718300 6107929 complement(209506..209835) 1 NC_010519.1 PFAM: DsrC family protein; KEGG: hso:HS_0329 sulfite reductase-like protein; DsrC family protein 209835 6107929 HSM_0200 Haemophilus somnus 2336 DsrC family protein YP_001783551.1 209506 R 228400 CDS YP_001783552.1 170718311 6107942 complement(209913..210575) 1 NC_010519.1 PFAM: protein of unknown function UPF0005; KEGG: hso:HS_0330 conserved integral membrane protein; hypothetical protein 210575 6107942 HSM_0201 Haemophilus somnus 2336 hypothetical protein YP_001783552.1 209913 R 228400 CDS YP_001783553.1 170718322 6108845 complement(210983..212512) 1 NC_010519.1 TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: hso:HS_0331 competence-related protein; Mg chelatase subunit ChlI 212512 6108845 HSM_0202 Haemophilus somnus 2336 Mg chelatase subunit ChlI YP_001783553.1 210983 R 228400 CDS YP_001783554.1 170718325 6107964 complement(212614..213309) 1 NC_010519.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 213309 engB 6107964 engB Haemophilus somnus 2336 ribosome biogenesis GTP-binding protein YsxC YP_001783554.1 212614 R 228400 CDS YP_001783555.1 170718326 6107966 complement(213230..214612) 1 NC_010519.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 214612 glmU 6107966 glmU Haemophilus somnus 2336 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_001783555.1 213230 R 228400 CDS YP_001783556.1 170718327 6107967 214658..215815 1 NC_010519.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 215815 anmK 6107967 anmK Haemophilus somnus 2336 anhydro-N-acetylmuramic acid kinase YP_001783556.1 214658 D 228400 CDS YP_001783557.1 170718328 6107968 215818..216729 1 NC_010519.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 216729 murQ 6107968 murQ Haemophilus somnus 2336 N-acetylmuramic acid 6-phosphate etherase YP_001783557.1 215818 D 228400 CDS YP_001783558.1 170718329 6107969 217017..217568 1 NC_010519.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: hso:HS_0336 NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase (quinone) 217568 6107969 HSM_0207 Haemophilus somnus 2336 NAD(P)H dehydrogenase (quinone) YP_001783558.1 217017 D 228400 CDS YP_001783559.1 170718330 6107970 217835..218533 1 NC_010519.1 KEGG: hso:HS_0337 hypothetical protein; hypothetical protein 218533 6107970 HSM_0208 Haemophilus somnus 2336 hypothetical protein YP_001783559.1 217835 D 228400 CDS YP_001783560.1 170718331 6107971 complement(218615..220303) 1 NC_010519.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK 220303 6107971 HSM_0209 Haemophilus somnus 2336 symporter YidK YP_001783560.1 218615 R 228400 CDS YP_001783561.1 170718333 6107972 220629..222389 1 NC_010519.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: hso:HS_0339 conserved outer membrane protein; surface antigen (D15) 222389 6107972 HSM_0210 Haemophilus somnus 2336 surface antigen (D15) YP_001783561.1 220629 D 228400 CDS YP_001783562.1 170718334 6107974 222400..225927 1 NC_010519.1 PFAM: protein of unknown function DUF490; KEGG: hso:HS_0340 hypothetical protein; hypothetical protein 225927 6107974 HSM_0211 Haemophilus somnus 2336 hypothetical protein YP_001783562.1 222400 D 228400 CDS YP_001783563.1 170718335 6107975 225930..227480 1 NC_010519.1 PFAM: Ppx/GppA phosphatase; KEGG: hso:HS_0341 exopolyphosphatase; Ppx/GppA phosphatase 227480 6107975 HSM_0212 Haemophilus somnus 2336 Ppx/GppA phosphatase YP_001783563.1 225930 D 228400 CDS YP_001783564.1 170718336 6107976 227653..229488 1 NC_010519.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 229488 6107976 HSM_0213 Haemophilus somnus 2336 dihydroxy-acid dehydratase YP_001783564.1 227653 D 228400 CDS YP_001783565.1 170718337 6107977 complement(229886..231130) 1 NC_010519.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 231130 clpX 6107977 clpX Haemophilus somnus 2336 ATP-dependent protease ATP-binding subunit ClpX YP_001783565.1 229886 R 228400 CDS YP_001783566.1 170718338 6107978 complement(231146..231727) 1 NC_010519.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 231727 clpP 6107978 clpP Haemophilus somnus 2336 ATP-dependent Clp protease proteolytic subunit YP_001783566.1 231146 R 228400 CDS YP_001783567.1 170718339 6107979 complement(231813..233111) 1 NC_010519.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 233111 tig 6107979 tig Haemophilus somnus 2336 trigger factor YP_001783567.1 231813 R 228400 CDS YP_001783568.1 170718340 6107980 233470..234885 1 NC_010519.1 PFAM: type II secretion system protein E; general secretory system II protein E domain protein; KEGG: hso:HS_1430 pilin/fimbriae biogenesis protein; type II secretion system protein E 234885 6107980 HSM_0217 Haemophilus somnus 2336 type II secretion system protein E YP_001783568.1 233470 D 228400 CDS YP_001783569.1 170718341 6107981 complement(234919..236178) 1 NC_010519.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: hso:HS_1429 transporter; hypothetical protein 236178 6107981 HSM_0218 Haemophilus somnus 2336 hypothetical protein YP_001783569.1 234919 R 228400 CDS YP_001783570.1 170718342 6107982 complement(236248..237045) 1 NC_010519.1 PFAM: cytochrome C assembly protein; KEGG: hso:HS_1428 permease; cytochrome C assembly protein 237045 6107982 HSM_0219 Haemophilus somnus 2336 cytochrome C assembly protein YP_001783570.1 236248 R 228400 CDS YP_001783571.1 170718344 6107983 237195..238571 1 NC_010519.1 TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54 helical bundle; SMART: ATPase AAA; KEGG: hso:HS_1427 signal recognition particle protein; signal recognition particle protein 238571 6107983 HSM_0220 Haemophilus somnus 2336 signal recognition particle protein YP_001783571.1 237195 D 228400 CDS YP_001783572.1 170718345 6107985 complement(238614..240353) 1 NC_010519.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM 240353 6107985 HSM_0221 Haemophilus somnus 2336 sulfate transporter YchM YP_001783572.1 238614 R 228400 CDS YP_001783573.1 170718346 6108846 240845..241798 1 NC_010519.1 KEGG: hit:NTHI0419 prophage CP4-57-like integrase; prophage CP4-57-like integrase 241798 6108846 HSM_0222 Haemophilus somnus 2336 prophage CP4-57-like integrase YP_001783573.1 240845 D 228400 CDS YP_001783574.1 170718347 6107987 complement(241901..243037) 1 NC_010519.1 TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: hso:HS_0583 transposase; IS605 family transposase OrfB 243037 6107987 HSM_0223 Haemophilus somnus 2336 IS605 family transposase OrfB YP_001783574.1 241901 R 228400 CDS YP_001783575.1 170718348 6107988 243084..243500 1 NC_010519.1 PFAM: transposase IS200-family protein; KEGG: hso:HS_0666 transposase; transposase IS200-family protein 243500 6107988 HSM_0224 Haemophilus somnus 2336 transposase IS200-family protein YP_001783575.1 243084 D 228400 CDS YP_001783576.1 170718349 6107989 complement(243787..244248) 1 NC_010519.1 hypothetical protein 244248 6107989 HSM_0225 Haemophilus somnus 2336 hypothetical protein YP_001783576.1 243787 R 228400 CDS YP_001783577.1 170718350 6107990 complement(244245..244697) 1 NC_010519.1 PFAM: phage head completion; KEGG: spt:SPA2617 phage gene; phage head completion 244697 6107990 HSM_0226 Haemophilus somnus 2336 phage head completion YP_001783577.1 244245 R 228400 CDS YP_001783578.1 170718351 6107991 complement(244690..245571) 1 NC_010519.1 PFAM: phage small terminase subunit; KEGG: yps:YPTB3143 hypothetical protein; phage small terminase subunit 245571 6107991 HSM_0227 Haemophilus somnus 2336 phage small terminase subunit YP_001783578.1 244690 R 228400 CDS YP_001783579.1 170718352 6107992 complement(245600..246631) 1 NC_010519.1 TIGRFAM: phage major capsid protein, P2 family; PFAM: phage major capsid protein P2; KEGG: pat:Patl_0697 phage major capsid protein, P2 family; P2 family phage major capsid protein 246631 6107992 HSM_0228 Haemophilus somnus 2336 P2 family phage major capsid protein YP_001783579.1 245600 R 228400 CDS YP_001783580.1 170718353 6107993 complement(246641..247066) 1 NC_010519.1 hypothetical protein 247066 6107993 HSM_0229 Haemophilus somnus 2336 hypothetical protein YP_001783580.1 246641 R 228400 CDS YP_001783581.1 170718355 6107994 complement(247017..247538) 1 NC_010519.1 PFAM: phage capsid scaffolding; KEGG: hch:HCH_00395 flagellar biosynthesis/type III secretory pathway protein; phage capsid scaffolding 247538 6107994 HSM_0230 Haemophilus somnus 2336 phage capsid scaffolding YP_001783581.1 247017 R 228400 CDS YP_001783582.1 170718356 6107996 247701..249488 1 NC_010519.1 PFAM: protein of unknown function DUF264; terminase ATPase; KEGG: yps:YPTB3140 [Haemophilus phage HP1] orf16-like phage protein; hypothetical protein 249488 6107996 HSM_0231 Haemophilus somnus 2336 hypothetical protein YP_001783582.1 247701 D 228400 CDS YP_001783583.1 170718357 6107997 249499..250527 1 NC_010519.1 TIGRFAM: phage portal protein, PBSX family; PFAM: phage portal protein; KEGG: sgl:SG0244 phage capsid portal protein; PBSX family phage portal protein 250527 6107997 HSM_0232 Haemophilus somnus 2336 PBSX family phage portal protein YP_001783583.1 249499 D 228400 CDS YP_001783584.1 170718358 6107998 250583..250861 1 NC_010519.1 PFAM: phage transcriptional activator Ogr/delta; KEGG: yps:YPTB3138 (AB008550) orf34 [bacteriophage phi CTX]; phage transcriptional activator Ogr/delta 250861 6107998 HSM_0233 Haemophilus somnus 2336 phage transcriptional activator Ogr/delta YP_001783584.1 250583 D 228400 CDS YP_001783585.1 170718359 6107999 complement(250962..251357) 1 NC_010519.1 hypothetical protein 251357 6107999 HSM_0234 Haemophilus somnus 2336 hypothetical protein YP_001783585.1 250962 R 228400 CDS YP_001783586.1 170718360 6108000 complement(251354..252739) 1 NC_010519.1 PFAM: N-6 DNA methylase; KEGG: ldb:Ldb1052 type I restriction-modification system, modification subunit; N-6 DNA methylase 252739 6108000 HSM_0235 Haemophilus somnus 2336 N-6 DNA methylase YP_001783586.1 251354 R 228400 CDS YP_001783587.1 170718361 6108001 complement(252756..253286) 1 NC_010519.1 hypothetical protein 253286 6108001 HSM_0236 Haemophilus somnus 2336 hypothetical protein YP_001783587.1 252756 R 228400 CDS YP_001783588.1 170718362 6108002 complement(253301..255490) 1 NC_010519.1 KEGG: pmu:PM1782 unknown; hypothetical protein 255490 6108002 HSM_0237 Haemophilus somnus 2336 hypothetical protein YP_001783588.1 253301 R 228400 CDS YP_001783589.1 170718363 6108003 complement(255487..255756) 1 NC_010519.1 hypothetical protein 255756 6108003 HSM_0238 Haemophilus somnus 2336 hypothetical protein YP_001783589.1 255487 R 228400 CDS YP_001783590.1 170718364 6108004 complement(255749..256237) 1 NC_010519.1 KEGG: hso:HS_0528 hypothetical protein; hypothetical protein 256237 6108004 HSM_0239 Haemophilus somnus 2336 hypothetical protein YP_001783590.1 255749 R 228400 CDS YP_001783591.1 170718366 6108005 complement(256389..256667) 1 NC_010519.1 KEGG: hso:HS_0527 hypothetical protein; hypothetical protein 256667 6108005 HSM_0240 Haemophilus somnus 2336 hypothetical protein YP_001783591.1 256389 R 228400 CDS YP_001783592.1 170718367 6108007 complement(256736..257500) 1 NC_010519.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: hit:NTHI1495 modification methylase DpnIIB-like; DNA methylase N-4/N-6 domain-containing protein 257500 6108007 HSM_0241 Haemophilus somnus 2336 DNA methylase N-4/N-6 domain-containing protein YP_001783592.1 256736 R 228400 CDS YP_001783593.1 170718368 6108008 complement(257511..257972) 1 NC_010519.1 KEGG: pmu:PM1778 unknown; hypothetical protein 257972 6108008 HSM_0242 Haemophilus somnus 2336 hypothetical protein YP_001783593.1 257511 R 228400 CDS YP_001783594.1 170718369 6108009 complement(258443..258724) 1 NC_010519.1 hypothetical protein 258724 6108009 HSM_0243 Haemophilus somnus 2336 hypothetical protein YP_001783594.1 258443 R 228400 CDS YP_001783595.1 170718370 6108010 complement(258693..258962) 1 NC_010519.1 hypothetical protein 258962 6108010 HSM_0244 Haemophilus somnus 2336 hypothetical protein YP_001783595.1 258693 R 228400 CDS YP_001783596.1 170718371 6108011 259257..259694 1 NC_010519.1 KEGG: vei:Veis_1323 hypothetical protein; hypothetical protein 259694 6108011 HSM_0245 Haemophilus somnus 2336 hypothetical protein YP_001783596.1 259257 D 228400 CDS YP_001783597.1 170718372 6108012 complement(261096..261314) 1 NC_010519.1 hypothetical protein 261314 6108012 HSM_0246 Haemophilus somnus 2336 hypothetical protein YP_001783597.1 261096 R 228400 CDS YP_001783598.1 170718373 6108013 complement(262158..262610) 1 NC_010519.1 KEGG: nma:NMA1837 hypothetical protein; hypothetical protein 262610 6108013 HSM_0247 Haemophilus somnus 2336 hypothetical protein YP_001783598.1 262158 R 228400 CDS YP_001783599.1 170718374 6108014 complement(262646..263011) 1 NC_010519.1 KEGG: nma:NMA1838 hypothetical DNA-binding protein; DNA-binding protein 263011 6108014 HSM_0248 Haemophilus somnus 2336 DNA-binding protein YP_001783599.1 262646 R 228400 CDS YP_001783600.1 170718375 6108015 263373..263696 1 NC_010519.1 TIGRFAM: Addiction module killer protein HI1419; PFAM: protein of unknown function DUF891; KEGG: bxe:Bxe_B0862 hypothetical protein; addiction module killer protein 263696 6108015 HSM_0249 Haemophilus somnus 2336 addiction module killer protein YP_001783600.1 263373 D 228400 CDS YP_001783601.1 170718377 6108016 263689..263988 1 NC_010519.1 TIGRFAM: Addiction module antidote protein HI1420; KEGG: pfo:Pfl_2007 predicted transcriptional regulator; transcriptional regulator 263988 6108016 HSM_0250 Haemophilus somnus 2336 transcriptional regulator YP_001783601.1 263689 D 228400 CDS YP_001783602.1 170718378 6108018 264628..265488 1 NC_010519.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 265488 6108018 HSM_0251 Haemophilus somnus 2336 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_001783602.1 264628 D 228400 CDS YP_001783603.1 170718379 6108019 265555..266385 1 NC_010519.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: hso:HS_1363 hypothetical protein; NAD-dependent epimerase/dehydratase 266385 6108019 HSM_0252 Haemophilus somnus 2336 NAD-dependent epimerase/dehydratase YP_001783603.1 265555 D 228400 CDS YP_001783604.1 170718380 6108020 266479..267813 1 NC_010519.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 267813 6108020 HSM_0253 Haemophilus somnus 2336 argininosuccinate synthase YP_001783604.1 266479 D 228400 CDS YP_001783605.1 170718381 6108021 267923..268810 1 NC_010519.1 PFAM: protein of unknown function DUF535; KEGG: hso:HS_1361 hypothetical protein; hypothetical protein 268810 6108021 HSM_0254 Haemophilus somnus 2336 hypothetical protein YP_001783605.1 267923 D 228400 CDS YP_001783606.1 170718382 6108022 268893..269348 1 NC_010519.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 269348 fabZ 6108022 fabZ Haemophilus somnus 2336 (3R)-hydroxymyristoyl-ACP dehydratase YP_001783606.1 268893 D 228400 CDS YP_001783607.1 170718383 6108023 269362..270150 1 NC_010519.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 270150 6108023 HSM_0256 Haemophilus somnus 2336 UDP-N-acetylglucosamine acyltransferase YP_001783607.1 269362 D 228400 CDS YP_001783608.1 170718384 6108024 270232..271401 1 NC_010519.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 271401 lpxB 6108024 lpxB Haemophilus somnus 2336 lipid-A-disaccharide synthase YP_001783608.1 270232 D 228400 CDS YP_001783609.1 170718385 6108025 271402..272037 1 NC_010519.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 272037 rnhB 6108025 rnhB Haemophilus somnus 2336 ribonuclease HII YP_001783609.1 271402 D 228400 CDS YP_001783610.1 170718386 6108026 272098..272682 1 NC_010519.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 272682 mogA 6108026 mogA Haemophilus somnus 2336 molybdenum cofactor biosynthesis protein MogA YP_001783610.1 272098 D 228400 CDS YP_001783611.1 170718388 6108027 272725..273063 1 NC_010519.1 PFAM: nitrogen regulatory protein P-II; KEGG: hso:HS_1355 nitrogen regulatory protein p-II; nitrogen regulatory protein P-II 273063 6108027 HSM_0260 Haemophilus somnus 2336 nitrogen regulatory protein P-II YP_001783611.1 272725 D 228400 CDS YP_001783612.1 170718389 6108029 273063..274115 1 NC_010519.1 PFAM: protein of unknown function UPF0118; KEGG: hso:HS_1354 permease; hypothetical protein 274115 6108029 HSM_0261 Haemophilus somnus 2336 hypothetical protein YP_001783612.1 273063 D 228400 CDS YP_001783613.1 170718390 6108030 complement(274430..275383) 1 NC_010519.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 275383 6108030 HSM_0262 Haemophilus somnus 2336 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_001783613.1 274430 R 228400 CDS YP_001783614.1 170718391 6108031 275468..275974 1 NC_010519.1 PFAM: Smr protein/MutS2; KEGG: hso:HS_1352 hypothetical protein; hypothetical protein 275974 6108031 HSM_0263 Haemophilus somnus 2336 hypothetical protein YP_001783614.1 275468 D 228400 CDS YP_001783615.1 170718392 6108032 complement(275976..278141) 1 NC_010519.1 TIGRFAM: hypothetical membrane protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: hso:HS_1351 membrane protein; hypothetical protein 278141 6108032 HSM_0264 Haemophilus somnus 2336 hypothetical protein YP_001783615.1 275976 R 228400 CDS YP_001783616.1 170718393 6108033 complement(278166..278624) 1 NC_010519.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 278624 mgsA 6108033 mgsA Haemophilus somnus 2336 methylglyoxal synthase YP_001783616.1 278166 R 228400 CDS YP_001783617.1 170718394 6108034 complement(278689..279342) 1 NC_010519.1 KEGG: hso:HS_1349 hypothetical protein; hypothetical protein 279342 6108034 HSM_0266 Haemophilus somnus 2336 hypothetical protein YP_001783617.1 278689 R 228400 CDS YP_001783618.1 170718395 6108035 279733..281478 1 NC_010519.1 PFAM: Hemolysin activator HlyB domain protein; polypeptide-transport-associated domain protein ShlB-type; KEGG: msu:MS1169 FhaC protein; polypeptide-transport-associated domain-containing protein 281478 6108035 HSM_0267 Haemophilus somnus 2336 polypeptide-transport-associated domain-containing protein YP_001783618.1 279733 D 228400 CDS YP_001783619.1 170718396 6108036 281512..288630 1 NC_010519.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: nme:NMB1768 hemagglutinin/hemolysin-related protein; filamentous hemagglutinin outer membrane protein 288630 6108036 HSM_0268 Haemophilus somnus 2336 filamentous hemagglutinin outer membrane protein YP_001783619.1 281512 D 228400 CDS YP_001783620.1 170718397 6108037 288599..288940 1 NC_010519.1 KEGG: nme:NMB1764 hypothetical protein; hypothetical protein 288940 6108037 HSM_0269 Haemophilus somnus 2336 hypothetical protein YP_001783620.1 288599 D 228400 CDS YP_001783621.1 170718399 6108038 289047..292526 1 NC_010519.1 KEGG: nme:NMB1768 hemagglutinin/hemolysin-related protein; hemagglutinin/hemolysin-like protein 292526 6108038 HSM_0270 Haemophilus somnus 2336 hemagglutinin/hemolysin-like protein YP_001783621.1 289047 D 228400 CDS YP_001783622.1 170718400 6108040 292546..293073 1 NC_010519.1 KEGG: nme:NMB1502 hypothetical protein; hypothetical protein 293073 6108040 HSM_0271 Haemophilus somnus 2336 hypothetical protein YP_001783622.1 292546 D 228400 CDS YP_001783623.1 170718401 6108041 293222..294907 1 NC_010519.1 KEGG: msu:MS1162 hypothetical protein; hypothetical protein 294907 6108041 HSM_0272 Haemophilus somnus 2336 hypothetical protein YP_001783623.1 293222 D 228400 CDS YP_001783624.1 170718402 6108042 294885..295271 1 NC_010519.1 hypothetical protein 295271 6108042 HSM_0273 Haemophilus somnus 2336 hypothetical protein YP_001783624.1 294885 D 228400 CDS YP_001783625.1 170718403 6108043 295335..296903 1 NC_010519.1 KEGG: mfa:Mfla_0483 adhesin HecA 20-residue repeat X2; adhesin 296903 6108043 HSM_0274 Haemophilus somnus 2336 adhesin YP_001783625.1 295335 D 228400 CDS YP_001783626.1 170718404 6108044 296905..297255 1 NC_010519.1 hypothetical protein 297255 6108044 HSM_0275 Haemophilus somnus 2336 hypothetical protein YP_001783626.1 296905 D 228400 CDS YP_001783627.1 170718405 6108045 297372..297707 1 NC_010519.1 hypothetical protein 297707 6108045 HSM_0276 Haemophilus somnus 2336 hypothetical protein YP_001783627.1 297372 D 228400 CDS YP_001783628.1 170718406 6108849 298438..299547 1 NC_010519.1 catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity; cystathionine gamma-synthase 299547 6108849 HSM_0277 Haemophilus somnus 2336 cystathionine gamma-synthase YP_001783628.1 298438 D 228400 CDS YP_001783629.1 170718407 6108047 299712..300035 1 NC_010519.1 TIGRFAM: thioredoxin; PFAM: thioredoxin domain; KEGG: hso:HS_1344 thioredoxin; thioredoxin 300035 6108047 HSM_0278 Haemophilus somnus 2336 thioredoxin YP_001783629.1 299712 D 228400 CDS YP_001783630.1 170718408 6108048 complement(300153..300848) 1 NC_010519.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 300848 6108048 HSM_0279 Haemophilus somnus 2336 DNA replication initiation factor YP_001783630.1 300153 R 228400 CDS YP_001783631.1 170718410 6108049 complement(300935..302176) 1 NC_010519.1 TIGRFAM: uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease; KEGG: hso:HS_1342 uracil permease; uracil-xanthine permease 302176 6108049 HSM_0280 Haemophilus somnus 2336 uracil-xanthine permease YP_001783631.1 300935 R 228400 CDS YP_001783632.1 170718411 6108051 complement(302278..302904) 1 NC_010519.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 302904 upp 6108051 upp Haemophilus somnus 2336 uracil phosphoribosyltransferase YP_001783632.1 302278 R 228400 CDS YP_001783633.1 170718412 6108052 complement(303044..303871) 1 NC_010519.1 PFAM: glutamine amidotransferase class-II; KEGG: hso:HS_1340 conserved hypothetical protein; glutamine amidotransferase 303871 6108052 HSM_0282 Haemophilus somnus 2336 glutamine amidotransferase YP_001783633.1 303044 R 228400 CDS YP_001783634.1 170718413 6108053 complement(304065..305414) 1 NC_010519.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 305414 6108053 HSM_0283 Haemophilus somnus 2336 glutamate dehydrogenase YP_001783634.1 304065 R 228400 CDS YP_001783635.1 170718414 6108054 305820..306425 1 NC_010519.1 KEGG: hso:HS_1338 hypothetical protein; hypothetical protein 306425 6108054 HSM_0284 Haemophilus somnus 2336 hypothetical protein YP_001783635.1 305820 D 228400 CDS YP_001783636.1 170718415 6108055 complement(307235..309025) 1 NC_010519.1 PFAM: glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: hso:HS_1330 beta-glucuronidase; beta-D-glucuronidase 309025 6108055 HSM_0285 Haemophilus somnus 2336 beta-D-glucuronidase YP_001783636.1 307235 R 228400 CDS YP_001783637.1 170718416 6108056 complement(309047..310075) 1 NC_010519.1 PFAM: PfkB domain protein; KEGG: hso:HS_1329 2-keto-3-deoxygluconate kinase; ribokinase-like domain-containing protein 310075 6108056 HSM_0286 Haemophilus somnus 2336 ribokinase-like domain-containing protein YP_001783637.1 309047 R 228400 CDS YP_001783638.1 170718417 6108057 310576..311874 1 NC_010519.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 311874 6108057 HSM_0287 Haemophilus somnus 2336 adenylosuccinate synthetase YP_001783638.1 310576 D 228400 CDS YP_001783639.1 170718418 6108058 complement(311940..313292) 1 NC_010519.1 PFAM: peptidase U62 modulator of DNA gyrase; KEGG: hso:HS_1327 antibiotic maturation factor; peptidase U62 modulator of DNA gyrase 313292 6108058 HSM_0288 Haemophilus somnus 2336 peptidase U62 modulator of DNA gyrase YP_001783639.1 311940 R 228400 CDS YP_001783640.1 170718419 6108059 313439..313972 1 NC_010519.1 PFAM: protein of unknown function DUF615; KEGG: hso:HS_1326 hypothetical protein; hypothetical protein 313972 6108059 HSM_0289 Haemophilus somnus 2336 hypothetical protein YP_001783640.1 313439 D 228400 CDS YP_001783641.1 170718421 6108060 314103..315638 1 NC_010519.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 315638 engA 6108060 engA Haemophilus somnus 2336 GTP-binding protein EngA YP_001783641.1 314103 D 228400 CDS YP_001783642.1 170718422 6108062 315806..316615 1 NC_010519.1 catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA; DNA ligase 316615 6108062 HSM_0291 Haemophilus somnus 2336 DNA ligase YP_001783642.1 315806 D 228400 CDS YP_001783643.1 170718423 6108063 316757..318133 1 NC_010519.1 PFAM: peptidase U32; KEGG: hso:HS_1323 collagenase PrtC; peptidase U32 318133 6108063 HSM_0292 Haemophilus somnus 2336 peptidase U32 YP_001783643.1 316757 D 228400 CDS YP_001783644.1 170718424 6108064 complement(318444..318632) 1 NC_010519.1 KEGG: hso:HS_1322 Haemophilus-specific protein, uncharacterized; hypothetical protein 318632 6108064 HSM_0293 Haemophilus somnus 2336 hypothetical protein YP_001783644.1 318444 R 228400 CDS YP_001783645.1 170718425 6108065 complement(318641..318913) 1 NC_010519.1 KEGG: hso:HS_1321 Haemophilus-specific protein, uncharacterized; hypothetical protein 318913 6108065 HSM_0294 Haemophilus somnus 2336 hypothetical protein YP_001783645.1 318641 R 228400 CDS YP_001783646.1 170718426 6108066 318940..319335 1 NC_010519.1 hypothetical protein 319335 6108066 HSM_0295 Haemophilus somnus 2336 hypothetical protein YP_001783646.1 318940 D 228400 CDS YP_001783647.1 170718427 6108067 319678..319806 1 NC_010519.1 KEGG: hso:HS_1320 Haemophilus-specific protein, uncharacterized; hypothetical protein 319806 6108067 HSM_0296 Haemophilus somnus 2336 hypothetical protein YP_001783647.1 319678 D 228400 CDS YP_001783648.1 170718428 6108068 320118..320258 1 NC_010519.1 KEGG: hso:HS_1319 C4-dicarboxylate transporter, C4-dicarboxylate-binding protein; hypothetical protein 320258 6108068 HSM_0297 Haemophilus somnus 2336 hypothetical protein YP_001783648.1 320118 D 228400 CDS YP_001783649.1 170718429 6108069 320321..321193 1 NC_010519.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_1319 C4-dicarboxylate transporter, C4-dicarboxylate-binding protein; TRAP dicarboxylate transporter subunit DctP 321193 6108069 HSM_0298 Haemophilus somnus 2336 TRAP dicarboxylate transporter subunit DctP YP_001783649.1 320321 D 228400 CDS YP_001783650.1 170718430 6108070 321190..321642 1 NC_010519.1 PFAM: tripartite ATP-independent periplasmic transporter DctQ component; KEGG: hso:HS_1318 C4-dicarboxylate transporter, small subunit; tripartite ATP-independent periplasmic transporter DctQ 321642 6108070 HSM_0299 Haemophilus somnus 2336 tripartite ATP-independent periplasmic transporter DctQ YP_001783650.1 321190 D 228400 CDS YP_001783651.1 170718433 6108071 321660..322928 1 NC_010519.1 TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: citrate transporter; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_1317 C4-dicarboxylate transporter, large subunit (permease); TRAP dicarboxylate transporter subunit DctM 322928 6108071 HSM_0300 Haemophilus somnus 2336 TRAP dicarboxylate transporter subunit DctM YP_001783651.1 321660 D 228400 CDS YP_001783652.1 170718434 6108074 323060..324130 1 NC_010519.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 324130 queA 6108074 queA Haemophilus somnus 2336 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_001783652.1 323060 D 228400 CDS YP_001783653.1 170718435 6108075 324175..325311 1 NC_010519.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 325311 tgt 6108075 tgt Haemophilus somnus 2336 queuine tRNA-ribosyltransferase YP_001783653.1 324175 D 228400 CDS YP_001783654.1 170718436 6108076 325467..325766 1 NC_010519.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 325766 yajC 6108076 yajC Haemophilus somnus 2336 preprotein translocase subunit YajC YP_001783654.1 325467 D 228400 CDS YP_001783655.1 170718437 6108077 325798..327648 1 NC_010519.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 327648 secD 6108077 secD Haemophilus somnus 2336 preprotein translocase subunit SecD YP_001783655.1 325798 D 228400 CDS YP_001783656.1 170718438 6108078 327661..328629 1 NC_010519.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 328629 secF 6108078 secF Haemophilus somnus 2336 preprotein translocase subunit SecF YP_001783656.1 327661 D 228400 CDS YP_001783657.1 170718439 6108850 complement(329205..329549) 1 NC_010519.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: hso:HS_1311 protein-export membrane protein; preprotein translocase subunit SecG 329549 secG 6108850 secG Haemophilus somnus 2336 preprotein translocase subunit SecG YP_001783657.1 329205 R 228400 CDS YP_001783658.1 170718440 6108080 complement(329687..331585) 1 NC_010519.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 331585 6108080 HSM_0307 Haemophilus somnus 2336 DNA topoisomerase III YP_001783658.1 329687 R 228400 CDS YP_001783659.1 170718441 6108081 331711..332040 1 NC_010519.1 PFAM: conserved hypothetical protein 103; KEGG: hso:HS_1309 hypothetical protein; hypothetical protein 332040 6108081 HSM_0308 Haemophilus somnus 2336 hypothetical protein YP_001783659.1 331711 D 228400 CDS YP_001783660.1 170718442 6108082 332103..332708 1 NC_010519.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 332708 recR 6108082 recR Haemophilus somnus 2336 recombination protein RecR YP_001783660.1 332103 D 228400 CDS YP_001783661.1 170718444 6108083 complement(332756..333943) 1 NC_010519.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 333943 6108083 HSM_0310 Haemophilus somnus 2336 tyrosyl-tRNA synthetase YP_001783661.1 332756 R 228400 CDS YP_001783662.1 170718445 6108086 complement(336349..338064) 1 NC_010519.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 338064 6108086 HSM_0313 Haemophilus somnus 2336 prolyl-tRNA synthetase YP_001783662.1 336349 R 228400 CDS YP_001783663.1 170718446 6108087 complement(338166..338630) 1 NC_010519.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 338630 recX 6108087 recX Haemophilus somnus 2336 recombination regulator RecX YP_001783663.1 338166 R 228400 CDS YP_001783664.1 170718447 6108088 complement(338739..339806) 1 NC_010519.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 339806 recA 6108088 recA Haemophilus somnus 2336 recombinase A YP_001783664.1 338739 R 228400 CDS YP_001783665.1 170718448 6108089 complement(339930..341849) 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1302 ABC transporter ATP-binding protein; ABC transporter 341849 6108089 HSM_0316 Haemophilus somnus 2336 ABC transporter YP_001783665.1 339930 R 228400 CDS YP_001783666.1 170718449 6108090 complement(342092..342724) 1 NC_010519.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: hso:HS_1301 FKBP-type peptidyl-prolyl cis-trans isomerase; FKBP-type peptidylprolyl isomerase 342724 6108090 HSM_0317 Haemophilus somnus 2336 FKBP-type peptidylprolyl isomerase YP_001783666.1 342092 R 228400 CDS YP_001783667.1 170718450 6108091 complement(342751..343635) 1 NC_010519.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 343635 psd 6108091 psd Haemophilus somnus 2336 phosphatidylserine decarboxylase YP_001783667.1 342751 R 228400 CDS YP_001783668.1 170718451 6108092 343932..344819 1 NC_010519.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 344819 xerC 6108092 xerC Haemophilus somnus 2336 site-specific tyrosine recombinase XerC YP_001783668.1 343932 D 228400 CDS YP_001783669.1 170718453 6108093 complement(344868..345236) 1 NC_010519.1 TIGRFAM: dihydroneopterin aldolase; KEGG: hso:HS_1298 dihydroneopterin aldolase; dihydroneopterin aldolase 345236 6108093 HSM_0320 Haemophilus somnus 2336 dihydroneopterin aldolase YP_001783669.1 344868 R 228400 CDS YP_001783670.1 170718454 6108095 345332..345913 1 NC_010519.1 PFAM: protein of unknown function DUF205; KEGG: hso:HS_1297 conserved hypothetical protein; hypothetical protein 345913 6108095 HSM_0321 Haemophilus somnus 2336 hypothetical protein YP_001783670.1 345332 D 228400 CDS YP_001783671.1 170718455 6108096 complement(345930..346640) 1 NC_010519.1 PFAM: methyltransferase small; KEGG: hso:HS_1296 SAM-dependent methyltransferase; methyltransferase small 346640 6108096 HSM_0322 Haemophilus somnus 2336 methyltransferase small YP_001783671.1 345930 R 228400 CDS YP_001783672.1 170718456 6108097 346723..348057 1 NC_010519.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 348057 6108097 HSM_0323 Haemophilus somnus 2336 ATP-dependent RNA helicase SrmB YP_001783672.1 346723 D 228400 CDS YP_001783673.1 170718457 6108098 complement(348094..348927) 1 NC_010519.1 PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: hso:HS_1294 conserved hypothetical protein; glycine cleavage T protein (aminomethyl transferase) 348927 6108098 HSM_0324 Haemophilus somnus 2336 glycine cleavage T protein (aminomethyl transferase) YP_001783673.1 348094 R 228400 CDS YP_001783674.1 170718458 6108099 complement(348936..349799) 1 NC_010519.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: hso:HS_1293 hypothetical protein; hypothetical protein 349799 6108099 HSM_0325 Haemophilus somnus 2336 hypothetical protein YP_001783674.1 348936 R 228400 CDS YP_001783675.1 170718459 6108100 349920..350636 1 NC_010519.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 350636 rph 6108100 rph Haemophilus somnus 2336 ribonuclease PH YP_001783675.1 349920 D 228400 CDS YP_001783676.1 170718460 6108101 350729..351598 1 NC_010519.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 351598 djlA 6108101 djlA Haemophilus somnus 2336 Dna-J like membrane chaperone protein YP_001783676.1 350729 D 228400 CDS YP_001783677.1 170718461 6108102 351603..352532 1 NC_010519.1 PFAM: dihydrouridine synthase; KEGG: hso:HS_1290 tRNA-dihydrouridine synthase C; dihydrouridine synthase 352532 6108102 HSM_0328 Haemophilus somnus 2336 dihydrouridine synthase YP_001783677.1 351603 D 228400 CDS YP_001783678.1 170718462 6108103 complement(352579..353145) 1 NC_010519.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 353145 6108103 HSM_0329 Haemophilus somnus 2336 elongation factor P YP_001783678.1 352579 R 228400 CDS YP_001783679.1 170718464 6108104 353181..354194 1 NC_010519.1 TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: radical SAM protein; KEGG: hso:HS_1288 hypothetical protein; lysine 2,3-aminomutase YodO family protein 354194 6108104 HSM_0330 Haemophilus somnus 2336 lysine 2,3-aminomutase YodO family protein YP_001783679.1 353181 D 228400 CDS YP_001783680.1 170718465 6108106 354288..355451 1 NC_010519.1 PFAM: Opacity-associated protein A; KEGG: hso:HS_1287 opacity associated protein A; opacity-associated protein A 355451 6108106 HSM_0331 Haemophilus somnus 2336 opacity-associated protein A YP_001783680.1 354288 D 228400 CDS YP_001783681.1 170718466 6108107 complement(355519..356424) 1 NC_010519.1 Required for efficient pilin antigenic variation; recombination associated protein 356424 rdgC 6108107 rdgC Haemophilus somnus 2336 recombination associated protein YP_001783681.1 355519 R 228400 CDS YP_001783682.1 170718467 6108108 356487..357302 1 NC_010519.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 357302 6108108 HSM_0333 Haemophilus somnus 2336 pyrroline-5-carboxylate reductase YP_001783682.1 356487 D 228400 CDS YP_001783683.1 170718468 6108109 357303..358502 1 NC_010519.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 358502 6108109 HSM_0334 Haemophilus somnus 2336 3-phenylpropionic acid transporter YP_001783683.1 357303 D 228400 CDS YP_001783684.1 170718469 6108110 358499..359392 1 NC_010519.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 359392 xerD 6108110 xerD Haemophilus somnus 2336 site-specific tyrosine recombinase XerD YP_001783684.1 358499 D 228400 CDS YP_001783685.1 170718470 6108111 359502..360248 1 NC_010519.1 KEGG: hso:HS_0337 hypothetical protein; hypothetical protein 360248 6108111 HSM_0336 Haemophilus somnus 2336 hypothetical protein YP_001783685.1 359502 D 228400 CDS YP_001783686.1 170718471 6108112 360404..361150 1 NC_010519.1 KEGG: hso:HS_0337 hypothetical protein; hypothetical protein 361150 6108112 HSM_0337 Haemophilus somnus 2336 hypothetical protein YP_001783686.1 360404 D 228400 CDS YP_001783687.1 170718472 6108113 complement(361328..368587) 1 NC_010519.1 PFAM: YadA domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790 large adhesin; YadA domain-containing protein 368587 6108113 HSM_0338 Haemophilus somnus 2336 YadA domain-containing protein YP_001783687.1 361328 R 228400 CDS YP_001783688.1 170718473 6108114 complement(369103..369891) 1 NC_010519.1 KEGG: hso:HS_1184 hypothetical protein; hypothetical protein 369891 6108114 HSM_0339 Haemophilus somnus 2336 hypothetical protein YP_001783688.1 369103 R 228400 CDS YP_001783689.1 170718475 6108115 370048..370764 1 NC_010519.1 PFAM: hypothetical protein; KEGG: hso:HS_1183 permease; hypothetical protein 370764 6108115 HSM_0340 Haemophilus somnus 2336 hypothetical protein YP_001783689.1 370048 D 228400 CDS YP_001783690.1 170718476 6108117 complement(370807..372219) 1 NC_010519.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: hso:HS_1548 outer membrane protein P1; aromatic hydrocarbon degradation membrane protein 372219 6108117 HSM_0341 Haemophilus somnus 2336 aromatic hydrocarbon degradation membrane protein YP_001783690.1 370807 R 228400 CDS YP_001783691.1 170718477 6108118 372565..373293 1 NC_010519.1 TIGRFAM: molybdenum ABC transporter periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_1182 molybdenum ABC transporter periplasmic binding protein; molybdenum ABC transporter periplasmic molybdate-binding protein 373293 6108118 HSM_0342 Haemophilus somnus 2336 molybdenum ABC transporter periplasmic molybdate-binding protein YP_001783691.1 372565 D 228400 CDS YP_001783692.1 170718478 6108119 373299..374009 1 NC_010519.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 374009 modB 6108119 modB Haemophilus somnus 2336 molybdate ABC transporter permease YP_001783692.1 373299 D 228400 CDS YP_001783693.1 170718479 6108120 374110..377070 1 NC_010519.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 377070 6108120 HSM_0344 Haemophilus somnus 2336 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_001783693.1 374110 D 228400 CDS YP_001783694.1 170718480 6108121 377185..377850 1 NC_010519.1 KEGG: hso:HS_1217 hypothetical protein; hypothetical protein 377850 6108121 HSM_0345 Haemophilus somnus 2336 hypothetical protein YP_001783694.1 377185 D 228400 CDS YP_001783695.1 170718481 6108122 complement(378185..382837) 1 NC_010519.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0209 large adhesin; YadA domain-containing protein 382837 6108122 HSM_0346 Haemophilus somnus 2336 YadA domain-containing protein YP_001783695.1 378185 R 228400 CDS YP_001783696.1 170718482 6108123 383421..384755 1 NC_010519.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 384755 xseA 6108123 xseA Haemophilus somnus 2336 exodeoxyribonuclease VII large subunit YP_001783696.1 383421 D 228400 CDS YP_001783697.1 170718483 6108124 complement(384808..385542) 1 NC_010519.1 PFAM: alanine racemase domain protein; KEGG: hso:HS_1215 hypothetical protein; alanine racemase 385542 6108124 HSM_0348 Haemophilus somnus 2336 alanine racemase YP_001783697.1 384808 R 228400 CDS YP_001783698.1 170718484 6108125 385832..388282 1 NC_010519.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 388282 thrA 6108125 thrA Haemophilus somnus 2336 bifunctional aspartokinase I/homoserine dehydrogenase I YP_001783698.1 385832 D 228400 CDS YP_001783699.1 170718486 6108126 388295..389239 1 NC_010519.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 389239 6108126 HSM_0350 Haemophilus somnus 2336 homoserine kinase YP_001783699.1 388295 D 228400 CDS YP_001783700.1 170718487 6108128 389252..390529 1 NC_010519.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 390529 6108128 HSM_0351 Haemophilus somnus 2336 threonine synthase YP_001783700.1 389252 D 228400 CDS YP_001783701.1 170718488 6108129 complement(390701..391147) 1 NC_010519.1 PFAM: ferric-uptake regulator; KEGG: hso:HS_1211 ferric uptake regulation protein; ferric uptake regulator family protein 391147 6108129 HSM_0352 Haemophilus somnus 2336 ferric uptake regulator family protein YP_001783701.1 390701 R 228400 CDS YP_001783702.1 170718489 6108130 complement(391164..391688) 1 NC_010519.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 391688 6108130 HSM_0353 Haemophilus somnus 2336 flavodoxin FldA YP_001783702.1 391164 R 228400 CDS YP_001783703.1 170718490 6108131 complement(392110..392889) 1 NC_010519.1 PFAM: alpha/beta hydrolase; PGAP1 family protein; KEGG: hso:HS_1209 esterase/lipase; alpha/beta hydrolase 392889 6108131 HSM_0354 Haemophilus somnus 2336 alpha/beta hydrolase YP_001783703.1 392110 R 228400 CDS YP_001783704.1 170718491 6108132 392995..393609 1 NC_010519.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 393609 6108132 HSM_0355 Haemophilus somnus 2336 replication initiation regulator SeqA YP_001783704.1 392995 D 228400 CDS YP_001783705.1 170718492 6108133 393612..395018 1 NC_010519.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: hso:HS_1207 O-succinylbenzoic acid--CoA ligase; O-succinylbenzoic acid--CoA ligase 395018 6108133 HSM_0356 Haemophilus somnus 2336 O-succinylbenzoic acid--CoA ligase YP_001783705.1 393612 D 228400 CDS YP_001783706.1 170718493 6108134 395021..398317 1 NC_010519.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 398317 6108134 HSM_0357 Haemophilus somnus 2336 potassium efflux protein KefA YP_001783706.1 395021 D 228400 CDS YP_001783707.1 170718494 6108135 398333..399415 1 NC_010519.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 399415 6108135 HSM_0358 Haemophilus somnus 2336 chorismate synthase YP_001783707.1 398333 D 228400 CDS YP_001783708.1 170718495 6108136 399448..400287 1 NC_010519.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 400287 mepA 6108136 mepA Haemophilus somnus 2336 penicillin-insensitive murein endopeptidase YP_001783708.1 399448 D 228400 CDS YP_001783709.1 170718497 6108137 400298..401068 1 NC_010519.1 PFAM: protein of unknown function DUF81; KEGG: hso:HS_1203 conserved hypothetical protein; hypothetical protein 401068 6108137 HSM_0360 Haemophilus somnus 2336 hypothetical protein YP_001783709.1 400298 D 228400 CDS YP_001783710.1 170718498 6108139 401092..402045 1 NC_010519.1 transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 402045 6108139 HSM_0361 Haemophilus somnus 2336 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_001783710.1 401092 D 228400 CDS YP_001783711.1 170718499 6108140 402116..402655 1 NC_010519.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 402655 6108140 HSM_0362 Haemophilus somnus 2336 adenine phosphoribosyltransferase YP_001783711.1 402116 D 228400 CDS YP_001783712.1 170718500 6108141 402686..404689 1 NC_010519.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma/tau 404689 6108141 HSM_0363 Haemophilus somnus 2336 DNA polymerase III subunits gamma/tau YP_001783712.1 402686 D 228400 CDS YP_001783713.1 170718501 6108142 404942..406060 1 NC_010519.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 406060 6108142 HSM_0364 Haemophilus somnus 2336 ribosomal RNA large subunit methyltransferase N YP_001783713.1 404942 D 228400 CDS YP_001783714.1 170718502 6108143 406091..406630 1 NC_010519.1 TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: hypothetical protein; Tetratricopeptide TPR_2 repeat protein; SMART: hypothetical protein; KEGG: hso:HS_1197 fimbrial biogenesis and twitching motility protein; type IV pilus biogenesis/stability protein PilW 406630 6108143 HSM_0365 Haemophilus somnus 2336 type IV pilus biogenesis/stability protein PilW YP_001783714.1 406091 D 228400 CDS YP_001783715.1 170718503 6108144 complement(406713..408983) 1 NC_010519.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 408983 6108144 HSM_0366 Haemophilus somnus 2336 ribonucleotide-diphosphate reductase subunit alpha YP_001783715.1 406713 R 228400 CDS YP_001783716.1 170718504 6108145 complement(409267..410388) 1 NC_010519.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 410388 6108145 HSM_0367 Haemophilus somnus 2336 chaperone protein DnaJ YP_001783716.1 409267 R 228400 CDS YP_001783717.1 170718505 6108146 complement(410486..412393) 1 NC_010519.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 412393 dnaK 6108146 dnaK Haemophilus somnus 2336 molecular chaperone DnaK YP_001783717.1 410486 R 228400 CDS YP_001783718.1 170718506 6108147 complement(412572..413825) 1 NC_010519.1 PFAM: polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; KEGG: hso:HS_1193 tRNA nucleotidyltransferase; polynucleotide adenylyltransferase/metal dependent phosphohydrolase 413825 6108147 HSM_0369 Haemophilus somnus 2336 polynucleotide adenylyltransferase/metal dependent phosphohydrolase YP_001783718.1 412572 R 228400 CDS YP_001783719.1 170718508 6108148 complement(413830..414441) 1 NC_010519.1 SMART: SH3 domain protein; KEGG: hso:HS_1192 hypothetical protein; SH3 domain-containing protein 414441 6108148 HSM_0370 Haemophilus somnus 2336 SH3 domain-containing protein YP_001783719.1 413830 R 228400 CDS YP_001783720.1 170718509 6108150 complement(414546..415808) 1 NC_010519.1 PFAM: phosphate transporter; KEGG: hso:HS_1191 phosphate permease; phosphate transporter 415808 6108150 HSM_0371 Haemophilus somnus 2336 phosphate transporter YP_001783720.1 414546 R 228400 CDS YP_001783721.1 170718510 6108151 complement(415835..416515) 1 NC_010519.1 PFAM: protein of unknown function DUF47; KEGG: hso:HS_1190 phosphate transport regulator; hypothetical protein 416515 6108151 HSM_0372 Haemophilus somnus 2336 hypothetical protein YP_001783721.1 415835 R 228400 CDS YP_001783722.1 170718511 6108152 416658..417701 1 NC_010519.1 PFAM: adenylate cyclase; KEGG: hso:HS_1189 hypothetical protein; adenylate cyclase 417701 6108152 HSM_0373 Haemophilus somnus 2336 adenylate cyclase YP_001783722.1 416658 D 228400 CDS YP_001783723.1 170718512 6108153 417711..419087 1 NC_010519.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 419087 6108153 HSM_0374 Haemophilus somnus 2336 DNA repair protein RadA YP_001783723.1 417711 D 228400 CDS YP_001783724.1 170718513 6108154 419189..419665 1 NC_010519.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid ABC transporterer; leucine-responsive transcriptional regulator 419665 6108154 HSM_0375 Haemophilus somnus 2336 leucine-responsive transcriptional regulator YP_001783724.1 419189 D 228400 CDS YP_001783725.1 170718514 6108155 419667..422378 1 NC_010519.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: hso:HS_1186 DNA translocase protein; cell division protein FtsK 422378 6108155 HSM_0376 Haemophilus somnus 2336 cell division protein FtsK YP_001783725.1 419667 D 228400 CDS YP_001783726.1 170718515 6108156 complement(422466..432413) 1 NC_010519.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1616 large adhesin; YadA domain-containing protein 432413 6108156 HSM_0377 Haemophilus somnus 2336 YadA domain-containing protein YP_001783726.1 422466 R 228400 CDS YP_001783727.1 170718516 6108157 complement(432942..433523) 1 NC_010519.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: hso:HS_1631 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase); FKBP-type peptidylprolyl isomerase 433523 6108157 HSM_0378 Haemophilus somnus 2336 FKBP-type peptidylprolyl isomerase YP_001783727.1 432942 R 228400 CDS YP_001783728.1 170718517 6108158 complement(433580..433993) 1 NC_010519.1 PFAM: protein of unknown function DUF1260; KEGG: hso:HS_1630 hypothetical protein; hypothetical protein 433993 6108158 HSM_0379 Haemophilus somnus 2336 hypothetical protein YP_001783728.1 433580 R 228400 CDS YP_001783729.1 170718519 6108159 complement(434010..434495) 1 NC_010519.1 TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: hso:HS_1629 tRNA/rRNA methyltransferase; RNA methyltransferase 434495 6108159 HSM_0380 Haemophilus somnus 2336 RNA methyltransferase YP_001783729.1 434010 R 228400 CDS YP_001783730.1 170718520 6108161 complement(434667..436283) 1 NC_010519.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 436283 6108161 HSM_0381 Haemophilus somnus 2336 phosphoenolpyruvate carboxykinase YP_001783730.1 434667 R 228400 CDS YP_001783731.1 170718521 6108162 complement(436463..437722) 1 NC_010519.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 437722 glyA 6108162 glyA Haemophilus somnus 2336 serine hydroxymethyltransferase YP_001783731.1 436463 R 228400 CDS YP_001783732.1 170718522 6108163 complement(437865..439163) 1 NC_010519.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 439163 6108163 HSM_0383 Haemophilus somnus 2336 phosphoribosylamine--glycine ligase YP_001783732.1 437865 R 228400 CDS YP_001783733.1 170718523 6108164 complement(439160..440776) 1 NC_010519.1 PFAM: sulfatase; KEGG: pmu:PM0223 DcaA protein; sulfatase 440776 6108164 HSM_0384 Haemophilus somnus 2336 sulfatase YP_001783733.1 439160 R 228400 CDS YP_001783734.1 170718524 6108165 complement(440792..442390) 1 NC_010519.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 442390 purH 6108165 purH Haemophilus somnus 2336 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_001783734.1 440792 R 228400 CDS YP_001783735.1 170718525 6108166 complement(442525..443034) 1 NC_010519.1 PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: hso:HS_1624 SprT protein; hypothetical protein 443034 6108166 HSM_0386 Haemophilus somnus 2336 hypothetical protein YP_001783735.1 442525 R 228400 CDS YP_001783736.1 170718526 6108167 complement(443112..444266) 1 NC_010519.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 444266 6108167 HSM_0387 Haemophilus somnus 2336 S-adenosylmethionine synthetase YP_001783736.1 443112 R 228400 CDS YP_001783737.1 170718527 6108168 444543..445121 1 NC_010519.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 445121 6108168 HSM_0388 Haemophilus somnus 2336 dinucleoside polyphosphate hydrolase YP_001783737.1 444543 D 228400 CDS YP_001783738.1 170718528 6108169 445132..445926 1 NC_010519.1 PFAM: protein of unknown function DUF81; KEGG: hso:HS_1621 permease; hypothetical protein 445926 6108169 HSM_0389 Haemophilus somnus 2336 hypothetical protein YP_001783738.1 445132 D 228400 CDS YP_001783739.1 170718530 6108170 445936..446748 1 NC_010519.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 446748 6108170 HSM_0390 Haemophilus somnus 2336 prolipoprotein diacylglyceryl transferase YP_001783739.1 445936 D 228400 CDS YP_001783740.1 170718531 6108172 446755..447606 1 NC_010519.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 447606 thyA 6108172 thyA Haemophilus somnus 2336 thymidylate synthase YP_001783740.1 446755 D 228400 CDS YP_001783741.1 170718532 6108173 447628..448128 1 NC_010519.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: hso:HS_1618 hypothetical protein; CMP/dCMP deaminase 448128 6108173 HSM_0392 Haemophilus somnus 2336 CMP/dCMP deaminase YP_001783741.1 447628 D 228400 CDS YP_001783742.1 170718533 6108174 complement(448099..450132) 1 NC_010519.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-subunit beta is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 450132 6108174 HSM_0393 Haemophilus somnus 2336 excinuclease ABC subunit B YP_001783742.1 448099 R 228400 CDS YP_001783743.1 170718534 6108175 450581..460450 1 NC_010519.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1616 large adhesin; YadA domain-containing protein 460450 6108175 HSM_0394 Haemophilus somnus 2336 YadA domain-containing protein YP_001783743.1 450581 D 228400 CDS YP_001783744.1 170718535 6108176 460772..462007 1 NC_010519.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; tryptophan halogenase; KEGG: hso:HS_1615 dehydrogenase; tryptophan halogenase 462007 6108176 HSM_0395 Haemophilus somnus 2336 tryptophan halogenase YP_001783744.1 460772 D 228400 CDS YP_001783745.1 170718536 6108177 462083..463690 1 NC_010519.1 PFAM: protein of unknown function DUF195; KEGG: hso:HS_1614 DNA recombination protein RmuC; hypothetical protein 463690 6108177 HSM_0396 Haemophilus somnus 2336 hypothetical protein YP_001783745.1 462083 D 228400 CDS YP_001783746.1 170718537 6108178 463750..464679 1 NC_010519.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 464679 rfaD 6108178 rfaD Haemophilus somnus 2336 ADP-L-glycero-D-manno-heptose-6-epimerase YP_001783746.1 463750 D 228400 CDS YP_001783747.1 170718538 6108179 464815..465855 1 NC_010519.1 TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9; KEGG: hso:HS_1612 ADP-heptose--LPS heptosyltransferase II; lipopolysaccharide heptosyltransferase II 465855 6108179 HSM_0398 Haemophilus somnus 2336 lipopolysaccharide heptosyltransferase II YP_001783747.1 464815 D 228400 CDS YP_001783748.1 170718539 6108180 465857..466822 1 NC_010519.1 TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: hso:HS_1611 lipopolysaccharide heptosyltransferase-1; ADP-heptose--LPS heptosyltransferase 466822 6108180 HSM_0399 Haemophilus somnus 2336 ADP-heptose--LPS heptosyltransferase YP_001783748.1 465857 D 228400 CDS YP_001783749.1 170718542 6108181 complement(466872..467696) 1 NC_010519.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 467696 dapF 6108181 dapF Haemophilus somnus 2336 diaminopimelate epimerase YP_001783749.1 466872 R 228400 CDS YP_001783750.1 170718543 6108184 468014..468646 1 NC_010519.1 KEGG: hso:HS_0337 hypothetical protein; hypothetical protein 468646 6108184 HSM_0401 Haemophilus somnus 2336 hypothetical protein YP_001783750.1 468014 D 228400 CDS YP_001783751.1 170718544 6108185 complement(468685..469182) 1 NC_010519.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; KEGG: hso:HS_1609 molybdopterin-guanine dinucleotide biosynthesis protein B; molybdopterin-guanine dinucleotide biosynthesis protein B 469182 6108185 HSM_0402 Haemophilus somnus 2336 molybdopterin-guanine dinucleotide biosynthesis protein B YP_001783751.1 468685 R 228400 CDS YP_001783752.1 170718545 6108186 complement(469196..469630) 1 NC_010519.1 PFAM: Positive regulator of sigma(E) RseC/MucC; KEGG: hso:HS_1608 positive sigma-E factor regulatory protein; sigma E positive regulator RseC/MucC 469630 6108186 HSM_0403 Haemophilus somnus 2336 sigma E positive regulator RseC/MucC YP_001783752.1 469196 R 228400 CDS YP_001783753.1 170718546 6108187 complement(469638..470576) 1 NC_010519.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 470576 rseB 6108187 rseB Haemophilus somnus 2336 periplasmic negative regulator of sigmaE YP_001783753.1 469638 R 228400 CDS YP_001783754.1 170718547 6108188 complement(470640..471224) 1 NC_010519.1 PFAM: anti sigma-E protein RseA family protein; anti sigma-E protein RseA domain protein; KEGG: hso:HS_1606 sigma-E factor negative regulatory protein; anti sigma-E protein RseA 471224 6108188 HSM_0405 Haemophilus somnus 2336 anti sigma-E protein RseA YP_001783754.1 470640 R 228400 CDS YP_001783755.1 170718548 6108189 complement(471257..471832) 1 NC_010519.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 471832 6108189 HSM_0406 Haemophilus somnus 2336 RNA polymerase sigma factor RpoE YP_001783755.1 471257 R 228400 CDS YP_001783756.1 170718549 6108190 complement(471938..472192) 1 NC_010519.1 PFAM: protein of unknown function DUF339; KEGG: hso:HS_1604 hypothetical protein; hypothetical protein 472192 6108190 HSM_0407 Haemophilus somnus 2336 hypothetical protein YP_001783756.1 471938 R 228400 CDS YP_001783757.1 170718550 6108191 complement(472366..473007) 1 NC_010519.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 473007 6108191 HSM_0408 Haemophilus somnus 2336 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_001783757.1 472366 R 228400 CDS YP_001783758.1 170718551 6108192 complement(473055..474458) 1 NC_010519.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 474458 6108192 HSM_0409 Haemophilus somnus 2336 glucuronate isomerase YP_001783758.1 473055 R 228400 CDS YP_001783759.1 170718553 6108193 complement(474468..475883) 1 NC_010519.1 TIGRFAM: sugar (glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_1601 glucuronide permease; sugar (glycoside-Pentoside-hexuronide) transporter 475883 6108193 HSM_0410 Haemophilus somnus 2336 sugar (glycoside-Pentoside-hexuronide) transporter YP_001783759.1 474468 R 228400 CDS YP_001783760.1 170718554 6108195 complement(475909..477669) 1 NC_010519.1 PFAM: glycoside hydrolase; KEGG: hso:HS_1600 beta-hexosamidase A, glycoside hydrolase family 3; glycoside hydrolase family protein 477669 6108195 HSM_0411 Haemophilus somnus 2336 glycoside hydrolase family protein YP_001783760.1 475909 R 228400 CDS YP_001783761.1 170718555 6108196 complement(477711..478526) 1 NC_010519.1 KEGG: hso:HS_1599 hypothetical protein; hypothetical protein 478526 6108196 HSM_0412 Haemophilus somnus 2336 hypothetical protein YP_001783761.1 477711 R 228400 CDS YP_001783762.1 170718556 6108197 complement(478536..479381) 1 NC_010519.1 Converts D-mannonate to D-mannuronate; D-mannonate oxidoreductase 479381 6108197 HSM_0413 Haemophilus somnus 2336 D-mannonate oxidoreductase YP_001783762.1 478536 R 228400 CDS YP_001783763.1 170718557 6108198 479631..480392 1 NC_010519.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: hso:HS_1597 uxu operon regulator; GntR family transcriptional regulator 480392 6108198 HSM_0414 Haemophilus somnus 2336 GntR family transcriptional regulator YP_001783763.1 479631 D 228400 CDS YP_001783764.1 170718558 6108199 480411..481595 1 NC_010519.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 481595 6108199 HSM_0415 Haemophilus somnus 2336 mannonate dehydratase YP_001783764.1 480411 D 228400 CDS YP_001783765.1 170718559 6108200 complement(481817..482344) 1 NC_010519.1 KEGG: hso:HS_1595 hypothetical protein; hypothetical protein 482344 6108200 HSM_0416 Haemophilus somnus 2336 hypothetical protein YP_001783765.1 481817 R 228400 CDS YP_001783766.1 170718560 6108201 482505..483116 1 NC_010519.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 483116 6108201 HSM_0417 Haemophilus somnus 2336 hypothetical protein YP_001783766.1 482505 D 228400 CDS YP_001783767.1 170718561 6108202 483140..484507 1 NC_010519.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 484507 6108202 HSM_0418 Haemophilus somnus 2336 adenylosuccinate lyase YP_001783767.1 483140 D 228400 CDS YP_001783768.1 170718562 6108203 complement(484587..485024) 1 NC_010519.1 KEGG: hso:HS_1592 acetyltransferase, GNAT family; GNAT family acetyltransferase 485024 6108203 HSM_0419 Haemophilus somnus 2336 GNAT family acetyltransferase YP_001783768.1 484587 R 228400 CDS YP_001783769.1 170718564 6108204 485192..485959 1 NC_010519.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 485959 tpiA 6108204 tpiA Haemophilus somnus 2336 triosephosphate isomerase YP_001783769.1 485192 D 228400 CDS YP_001783770.1 170718565 6108206 486057..487337 1 NC_010519.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 487337 6108206 HSM_0421 Haemophilus somnus 2336 3-deoxy-D-manno-octulosonic-acid transferase YP_001783770.1 486057 D 228400 CDS YP_001783771.1 170718566 6108207 487337..487813 1 NC_010519.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 487813 coaD 6108207 coaD Haemophilus somnus 2336 phosphopantetheine adenylyltransferase YP_001783771.1 487337 D 228400 CDS YP_001783772.1 170718567 6108208 487887..489725 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1588 ABC transporter permease/ATP-binding protein; ABC transporter 489725 6108208 HSM_0423 Haemophilus somnus 2336 ABC transporter YP_001783772.1 487887 D 228400 CDS YP_001783773.1 170718568 6108209 complement(489808..490683) 1 NC_010519.1 PFAM: myo-inositol catabolism IolB domain protein; KEGG: hso:HS_1587 conserved hypothetical protein; myo-inositol catabolism IolB domain-containing protein 490683 6108209 HSM_0424 Haemophilus somnus 2336 myo-inositol catabolism IolB domain-containing protein YP_001783773.1 489808 R 228400 CDS YP_001783774.1 170718569 6108210 490875..492260 1 NC_010519.1 PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_1586 permease, MFS superfamily; major facilitator transporter 492260 6108210 HSM_0425 Haemophilus somnus 2336 major facilitator transporter YP_001783774.1 490875 D 228400 CDS YP_001783775.1 170718570 6108211 492271..493119 1 NC_010519.1 KEGG: hso:HS_1585 hypothetical protein; hypothetical protein 493119 6108211 HSM_0426 Haemophilus somnus 2336 hypothetical protein YP_001783775.1 492271 D 228400 CDS YP_001783776.1 170718571 6108212 493280..494788 1 NC_010519.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: hso:HS_1584 NAD-dependent aldehyde dehydrogenase; methylmalonate-semialdehyde dehydrogenase 494788 6108212 HSM_0427 Haemophilus somnus 2336 methylmalonate-semialdehyde dehydrogenase YP_001783776.1 493280 D 228400 CDS YP_001783777.1 170718572 6108213 494872..496008 1 NC_010519.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: hso:HS_1583 dehydrogenase; oxidoreductase domain-containing protein 496008 6108213 HSM_0428 Haemophilus somnus 2336 oxidoreductase domain-containing protein YP_001783777.1 494872 D 228400 CDS YP_001783778.1 170718573 6108214 496303..497238 1 NC_010519.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_1582 ABC transporter periplasmic sugar-binding protein; monosaccharide-transporting ATPase 497238 6108214 HSM_0429 Haemophilus somnus 2336 monosaccharide-transporting ATPase YP_001783778.1 496303 D 228400 CDS YP_001783779.1 170718575 6108215 497325..498260 1 NC_010519.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_1581 ABC transporter periplasmic sugar-binding protein; monosaccharide-transporting ATPase 498260 6108215 HSM_0430 Haemophilus somnus 2336 monosaccharide-transporting ATPase YP_001783779.1 497325 D 228400 CDS YP_001783780.1 170718576 6108217 498341..499858 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1580 sugar ABC transporter ATP-binding protein; ABC transporter 499858 6108217 HSM_0431 Haemophilus somnus 2336 ABC transporter YP_001783780.1 498341 D 228400 CDS YP_001783781.1 170718577 6108218 499896..500852 1 NC_010519.1 PFAM: inner-membrane translocator; KEGG: hso:HS_1579 ABC transporter ribose permease; monosaccharide-transporting ATPase 500852 6108218 HSM_0432 Haemophilus somnus 2336 monosaccharide-transporting ATPase YP_001783781.1 499896 D 228400 CDS YP_001783782.1 170718578 6108219 501039..502976 1 NC_010519.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: hso:HS_1578 myo-inositol catabolism protein; thiamine pyrophosphate protein central region 502976 6108219 HSM_0433 Haemophilus somnus 2336 thiamine pyrophosphate protein central region YP_001783782.1 501039 D 228400 CDS YP_001783783.1 170718579 6108220 503050..503946 1 NC_010519.1 PFAM: xylose isomerase; KEGG: hso:HS_1577 myo-inositol catabolism protein; xylose isomerase 503946 6108220 HSM_0434 Haemophilus somnus 2336 xylose isomerase YP_001783783.1 503050 D 228400 CDS YP_001783784.1 170718580 6108221 503948..504958 1 NC_010519.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: hso:HS_1576 dehydrogenase; inositol 2-dehydrogenase 504958 6108221 HSM_0435 Haemophilus somnus 2336 inositol 2-dehydrogenase YP_001783784.1 503948 D 228400 CDS YP_001783785.2 229220771 6108222 complement(505019..505756) 1 NC_010519.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 505756 6108222 HSM_0436 Haemophilus somnus 2336 16S ribosomal RNA methyltransferase RsmE YP_001783785.2 505019 R 228400 CDS YP_001783786.1 170718582 6108223 complement(505874..507184) 1 NC_010519.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 507184 potE 6108223 potE Haemophilus somnus 2336 putrescine transporter YP_001783786.1 505874 R 228400 CDS YP_001783787.1 170718583 6108224 complement(507242..509401) 1 NC_010519.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: hso:HS_1573 ornithine decarboxylase; ornithine decarboxylase 509401 6108224 HSM_0438 Haemophilus somnus 2336 ornithine decarboxylase YP_001783787.1 507242 R 228400 CDS YP_001783788.1 170718584 6108225 complement(509682..509846) 1 NC_010519.1 KEGG: pmu:PM0805 unknown; hypothetical protein 509846 6108225 HSM_0439 Haemophilus somnus 2336 hypothetical protein YP_001783788.1 509682 R 228400 CDS YP_001783789.1 170718586 6108226 complement(510013..510345) 1 NC_010519.1 PFAM: SirA family protein; KEGG: hso:HS_1572 hypothetical protein; SirA family protein 510345 6108226 HSM_0440 Haemophilus somnus 2336 SirA family protein YP_001783789.1 510013 R 228400 CDS YP_001783790.1 170718587 6108228 510325..510933 1 NC_010519.1 PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: hso:HS_1571 hypothetical protein; hypothetical protein 510933 6108228 HSM_0441 Haemophilus somnus 2336 hypothetical protein YP_001783790.1 510325 D 228400 CDS YP_001783791.1 170718588 6108229 510945..512408 1 NC_010519.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: hso:HS_1570 potassium uptake system protein; TrkH family potassium uptake protein 512408 6108229 HSM_0442 Haemophilus somnus 2336 TrkH family potassium uptake protein YP_001783791.1 510945 D 228400 CDS YP_001783792.1 170718589 6108230 512408..512920 1 NC_010519.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 512920 hemG 6108230 hemG Haemophilus somnus 2336 protoporphyrinogen oxidase YP_001783792.1 512408 D 228400 CDS YP_001783793.1 170718590 6108855 519037..519393 1 NC_010519.1 KEGG: bce:BC4488 hypothetical protein; hypothetical protein 519393 6108855 HSM_0445 Haemophilus somnus 2336 hypothetical protein YP_001783793.1 519037 D 228400 CDS YP_001783794.1 170718591 6108232 519568..522381 1 NC_010519.1 KEGG: cps:CPS_2955 hypothetical protein; exonuclease V subunit alpha 522381 6108232 HSM_0446 Haemophilus somnus 2336 exonuclease V subunit alpha YP_001783794.1 519568 D 228400 CDS YP_001783795.1 170718592 6108233 522375..522641 1 NC_010519.1 hypothetical protein 522641 6108233 HSM_0447 Haemophilus somnus 2336 hypothetical protein YP_001783795.1 522375 D 228400 CDS YP_001783796.1 170718594 6108235 complement(524912..525670) 1 NC_010519.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 525670 6108235 HSM_0450 Haemophilus somnus 2336 uridine phosphorylase YP_001783796.1 524912 R 228400 CDS YP_001783797.1 170718595 6108237 525954..526772 1 NC_010519.1 KEGG: hso:HS_1518 hypothetical protein; hypothetical protein 526772 6108237 HSM_0451 Haemophilus somnus 2336 hypothetical protein YP_001783797.1 525954 D 228400 CDS YP_001783798.1 170718596 6108238 complement(526787..527095) 1 NC_010519.1 PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIsubunit alpha; KEGG: vfi:VF0607 PTS system, diacetylchitobiose-specific IIA component; PTS system lactose/cellobiose-specific transporter subunit IIA 527095 6108238 HSM_0452 Haemophilus somnus 2336 PTS system lactose/cellobiose-specific transporter subunit IIA YP_001783798.1 526787 R 228400 CDS YP_001783799.1 170718597 6108239 complement(527092..527403) 1 NC_010519.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIsubunit beta; KEGG: vfi:VF0604 PTS system, cellobiose-specific IIB component; PTS system lactose/cellobiose-specific transporter subunit IIB 527403 6108239 HSM_0453 Haemophilus somnus 2336 PTS system lactose/cellobiose-specific transporter subunit IIB YP_001783799.1 527092 R 228400 CDS YP_001783800.1 170718598 6108240 complement(527413..528858) 1 NC_010519.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: rma:Rmag_0211 leucyl aminopeptidase; leucyl aminopeptidase 528858 6108240 HSM_0454 Haemophilus somnus 2336 leucyl aminopeptidase YP_001783800.1 527413 R 228400 CDS YP_001783801.1 170718599 6108241 complement(528855..529817) 1 NC_010519.1 PFAM: peptidase T2 asparaginase 2; KEGG: lga:LGAS_1433 asparaginase; asparaginase 529817 6108241 HSM_0455 Haemophilus somnus 2336 asparaginase YP_001783801.1 528855 R 228400 CDS YP_001783802.1 170718600 6108242 complement(529818..531092) 1 NC_010519.1 TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PTS system, cellobiose-specific IIC subunit; PFAM: phosphotransferase system EIIC; KEGG: bsu:BG10562 PTS cellobiose-specific enzyme IIC component; PTS system lactose/cellobiose family transporter subunit IIC 531092 6108242 HSM_0456 Haemophilus somnus 2336 PTS system lactose/cellobiose family transporter subunit IIC YP_001783802.1 529818 R 228400 CDS YP_001783803.1 170718601 6108243 531276..532007 1 NC_010519.1 PFAM: CutC family protein; KEGG: hso:HS_1517 copper homeostasis protein; CutC family protein 532007 6108243 HSM_0457 Haemophilus somnus 2336 CutC family protein YP_001783803.1 531276 D 228400 CDS YP_001783804.1 170718602 6108244 532182..535082 1 NC_010519.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 535082 6108244 HSM_0458 Haemophilus somnus 2336 ATP-dependent helicase HepA YP_001783804.1 532182 D 228400 CDS YP_001783805.1 170718603 6108245 535084..535749 1 NC_010519.1 PFAM: pseudouridine synthase; KEGG: hso:HS_1515 ribosomal large subunit pseudouridine synthase A; pseudouridine synthase 535749 6108245 HSM_0459 Haemophilus somnus 2336 pseudouridine synthase YP_001783805.1 535084 D 228400 CDS YP_001783806.1 170718605 6108246 complement(535812..536576) 1 NC_010519.1 PFAM: peptidase M48 Ste24p; KEGG: hso:HS_1514 hypothetical protein; peptidase M48 Ste24p 536576 6108246 HSM_0460 Haemophilus somnus 2336 peptidase M48 Ste24p YP_001783806.1 535812 R 228400 CDS YP_001783807.1 170718606 6108248 complement(536635..537162) 1 NC_010519.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 537162 6108248 HSM_0461 Haemophilus somnus 2336 inorganic pyrophosphatase YP_001783807.1 536635 R 228400 CDS YP_001783808.1 170718607 6108249 537334..538584 1 NC_010519.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; KEGG: hso:HS_1562 tryptophan-specific transporter; aromatic amino acid transporter 538584 6108249 HSM_0462 Haemophilus somnus 2336 aromatic amino acid transporter YP_001783808.1 537334 D 228400 CDS YP_001783809.1 170718608 6108250 538744..539286 1 NC_010519.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 539286 6108250 HSM_0463 Haemophilus somnus 2336 bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase YP_001783809.1 538744 D 228400 CDS YP_001783810.1 170718609 6108251 539348..540313 1 NC_010519.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: hso:HS_1560 peptidyl-prolyl cis-trans isomerase, PPIC-type; PpiC-type peptidyl-prolyl cis-trans isomerase 540313 6108251 HSM_0464 Haemophilus somnus 2336 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001783810.1 539348 D 228400 CDS YP_001783811.1 170718610 6108252 540389..541234 1 NC_010519.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 541234 ksgA 6108252 ksgA Haemophilus somnus 2336 dimethyladenosine transferase YP_001783811.1 540389 D 228400 CDS YP_001783812.1 170718611 6108253 541285..542106 1 NC_010519.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 542106 apaH 6108253 apaH Haemophilus somnus 2336 diadenosine tetraphosphatase YP_001783812.1 541285 D 228400 CDS YP_001783813.1 170718612 6108254 542393..544975 1 NC_010519.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 544975 leuS 6108254 leuS Haemophilus somnus 2336 leucyl-tRNA synthetase YP_001783813.1 542393 D 228400 CDS YP_001783814.1 170718613 6108255 545024..545527 1 NC_010519.1 PFAM: Rare lipoprotein B; KEGG: hso:HS_1556 conserved hypothetical protein; rare lipoprotein B 545527 6108255 HSM_0468 Haemophilus somnus 2336 rare lipoprotein B YP_001783814.1 545024 D 228400 CDS YP_001783815.1 170718614 6108256 545527..546567 1 NC_010519.1 required for the assembly and function of the DNAX complex which is required for the assembly of the subunit beta onto primed DNA; DNA polymerase III subunit delta 546567 holA 6108256 holA Haemophilus somnus 2336 DNA polymerase III subunit delta YP_001783815.1 545527 D 228400 CDS YP_001783816.1 170718616 6108257 546694..547344 1 NC_010519.1 TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: ATPase AAA; KEGG: hso:HS_1554 cell-division ATP-binding protein; cell division ATP-binding protein FtsE 547344 6108257 HSM_0470 Haemophilus somnus 2336 cell division ATP-binding protein FtsE YP_001783816.1 546694 D 228400 CDS YP_001783817.1 170718617 6108259 547354..548292 1 NC_010519.1 ABC transporter membrane protein; cell division protein FtsX 548292 ftsX 6108259 ftsX Haemophilus somnus 2336 cell division protein FtsX YP_001783817.1 547354 D 228400 CDS YP_001783818.1 170718618 6108260 548419..549534 1 NC_010519.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 549534 6108260 HSM_0472 Haemophilus somnus 2336 aspartate-semialdehyde dehydrogenase YP_001783818.1 548419 D 228400 CDS YP_001783819.1 170718619 6108261 complement(549727..550764) 1 NC_010519.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 550764 6108261 HSM_0473 Haemophilus somnus 2336 phosphoribosylaminoimidazole synthetase YP_001783819.1 549727 R 228400 CDS YP_001783820.1 170718620 6108262 complement(550953..551627) 1 NC_010519.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 551627 6108262 HSM_0474 Haemophilus somnus 2336 DNA mismatch repair protein YP_001783820.1 550953 R 228400 CDS YP_001783821.1 170718621 6108263 complement(551624..552166) 1 NC_010519.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: hso:HS_1549 methylated-DNA-protein-cysteine methyltransferase; methylated-DNA--protein-cysteine methyltransferase 552166 6108263 HSM_0475 Haemophilus somnus 2336 methylated-DNA--protein-cysteine methyltransferase YP_001783821.1 551624 R 228400 CDS YP_001783822.1 170718622 6108264 complement(552218..553408) 1 NC_010519.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: hso:HS_1548 outer membrane protein P1; aromatic hydrocarbon degradation membrane protein 553408 6108264 HSM_0476 Haemophilus somnus 2336 aromatic hydrocarbon degradation membrane protein YP_001783822.1 552218 R 228400 CDS YP_001783823.1 170718623 6108265 complement(553398..553649) 1 NC_010519.1 KEGG: hso:HS_1548 outer membrane protein P1; outer membrane protein P1 553649 6108265 HSM_0477 Haemophilus somnus 2336 outer membrane protein P1 YP_001783823.1 553398 R 228400 CDS YP_001783824.1 170718624 6108266 553890..554186 1 NC_010519.1 PFAM: conserved hypothetical protein 743; KEGG: hso:HS_1547 hypothetical protein; hypothetical protein 554186 6108266 HSM_0478 Haemophilus somnus 2336 hypothetical protein YP_001783824.1 553890 D 228400 CDS YP_001783825.1 170718625 6108267 554339..555028 1 NC_010519.1 PFAM: pirin; Cupin 2 conserved barrel domain protein; KEGG: hso:HS_1546 conserved hypothetical protein; pirin domain-containing protein 555028 6108267 HSM_0479 Haemophilus somnus 2336 pirin domain-containing protein YP_001783825.1 554339 D 228400 CDS YP_001783826.1 170718627 6108268 complement(555136..555978) 1 NC_010519.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 555978 6108268 HSM_0480 Haemophilus somnus 2336 RNA polymerase factor sigma-32 YP_001783826.1 555136 R 228400 CDS YP_001783827.1 170718628 6108270 complement(556101..556415) 1 NC_010519.1 KEGG: hso:HS_1544 hypothetical protein; hypothetical protein 556415 6108270 HSM_0481 Haemophilus somnus 2336 hypothetical protein YP_001783827.1 556101 R 228400 CDS YP_001783828.1 170718629 6108271 complement(556431..557456) 1 NC_010519.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 557456 murB 6108271 murB Haemophilus somnus 2336 UDP-N-acetylenolpyruvoylglucosamine reductase YP_001783828.1 556431 R 228400 CDS YP_001783829.1 170718630 6108272 complement(557466..559244) 1 NC_010519.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: hso:HS_1510 nitrate/nitrite sensor protein; nitrate/nitrite sensor protein NarQ 559244 6108272 HSM_0483 Haemophilus somnus 2336 nitrate/nitrite sensor protein NarQ YP_001783829.1 557466 R 228400 CDS YP_001783830.1 170718631 6108273 559358..562198 1 NC_010519.1 PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases; KEGG: dvl:Dvul_0853 type III restriction enzyme, res subunit; type III restriction protein res subunit 562198 6108273 HSM_0484 Haemophilus somnus 2336 type III restriction protein res subunit YP_001783830.1 559358 D 228400 CDS YP_001783831.1 170718632 6108274 562219..563214 1 NC_010519.1 KEGG: hit:NTHI0317 conserved hypothetical DNA binding protein; DNA binding protein 563214 6108274 HSM_0485 Haemophilus somnus 2336 DNA binding protein YP_001783831.1 562219 D 228400 CDS YP_001783832.1 170718633 6108275 563222..564637 1 NC_010519.1 PFAM: restriction modification system DNA specificity domain; KEGG: mbu:Mbur_0508 restriction modification system DNA specificity subunit; restriction modification system DNA specificity subunit 564637 6108275 HSM_0486 Haemophilus somnus 2336 restriction modification system DNA specificity subunit YP_001783832.1 563222 D 228400 CDS YP_001783833.1 170718634 6108276 564631..564834 1 NC_010519.1 hypothetical protein 564834 6108276 HSM_0487 Haemophilus somnus 2336 hypothetical protein YP_001783833.1 564631 D 228400 CDS YP_001783834.1 170718635 6108277 564878..565087 1 NC_010519.1 hypothetical protein 565087 6108277 HSM_0488 Haemophilus somnus 2336 hypothetical protein YP_001783834.1 564878 D 228400 CDS YP_001783835.1 170718636 6108278 565134..566492 1 NC_010519.1 KEGG: gka:GK0575 hypothetical protein; transcriptional regulator 566492 6108278 HSM_0489 Haemophilus somnus 2336 transcriptional regulator YP_001783835.1 565134 D 228400 CDS YP_001783836.1 170718638 6108281 568291..568572 1 NC_010519.1 PFAM: NapD family protein; KEGG: hso:HS_1509 periplasmic nitrate reductase, component NapD; NapD family protein 568572 6108281 HSM_0492 Haemophilus somnus 2336 NapD family protein YP_001783836.1 568291 D 228400 CDS YP_001783837.1 170718639 6108282 568599..571082 1 NC_010519.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 571082 6108282 HSM_0493 Haemophilus somnus 2336 nitrate reductase catalytic subunit YP_001783837.1 568599 D 228400 CDS YP_001783838.1 170718640 6108283 571133..571885 1 NC_010519.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 571885 napG 6108283 napG Haemophilus somnus 2336 quinol dehydrogenase periplasmic component YP_001783838.1 571133 D 228400 CDS YP_001783839.1 170718641 6108284 571885..572757 1 NC_010519.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 572757 napH 6108284 napH Haemophilus somnus 2336 quinol dehydrogenase membrane component YP_001783839.1 571885 D 228400 CDS YP_001783840.1 170718642 6108285 572754..573179 1 NC_010519.1 PFAM: nitrate reductase cytochrome C subunit (NapB); KEGG: hso:HS_1505 periplasmic nitrate reductase; nitrate reductase cytochrome c-type subunit NapB 573179 6108285 HSM_0496 Haemophilus somnus 2336 nitrate reductase cytochrome c-type subunit NapB YP_001783840.1 572754 D 228400 CDS YP_001783841.1 170718643 6108286 573194..573805 1 NC_010519.1 PFAM: NapC/NirT cytochrome C domain protein; KEGG: hso:HS_1504 cytochrome C protein; NapC/NirT cytochrome C domain-containing protein 573805 6108286 HSM_0497 Haemophilus somnus 2336 NapC/NirT cytochrome C domain-containing protein YP_001783841.1 573194 D 228400 CDS YP_001783842.1 170718644 6108287 complement(573900..577793) 1 NC_010519.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 577793 6108287 HSM_0498 Haemophilus somnus 2336 phosphoribosylformylglycinamidine synthase YP_001783842.1 573900 R 228400 CDS YP_001783843.1 170718645 6108288 complement(577974..579011) 1 NC_010519.1 PFAM: peptidoglycan-binding LysM; peptidase M23B; KEGG: hso:HS_1502 lipoprotein B; peptidase M23B 579011 6108288 HSM_0499 Haemophilus somnus 2336 peptidase M23B YP_001783843.1 577974 R 228400 CDS YP_001783844.1 170718648 6108289 complement(579052..579627) 1 NC_010519.1 PFAM: SNARE associated Golgi protein; KEGG: hso:HS_1501 lipoprotein B; hypothetical protein 579627 6108289 HSM_0500 Haemophilus somnus 2336 hypothetical protein YP_001783844.1 579052 R 228400 CDS YP_001783845.1 170718649 6108292 complement(579657..580397) 1 NC_010519.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 580397 surE 6108292 surE Haemophilus somnus 2336 stationary phase survival protein SurE YP_001783845.1 579657 R 228400 CDS YP_001783846.1 170718650 6108293 complement(580421..581428) 1 NC_010519.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 581428 truD 6108293 truD Haemophilus somnus 2336 tRNA pseudouridine synthase D YP_001783846.1 580421 R 228400 CDS YP_001783847.1 170718651 6108294 complement(581428..581916) 1 NC_010519.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 581916 ispF 6108294 ispF Haemophilus somnus 2336 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_001783847.1 581428 R 228400 CDS YP_001783848.1 170718652 6108295 complement(581929..583734) 1 NC_010519.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: hso:HS_1497 glutathione-regulated potassium-efflux system protein; potassium efflux system protein 583734 6108295 HSM_0504 Haemophilus somnus 2336 potassium efflux system protein YP_001783848.1 581929 R 228400 CDS YP_001783849.1 170718653 6108296 complement(583740..584423) 1 NC_010519.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 584423 ispD 6108296 ispD Haemophilus somnus 2336 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_001783849.1 583740 R 228400 CDS YP_001783850.1 170718654 6108297 complement(584424..584705) 1 NC_010519.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 584705 ftsB 6108297 ftsB Haemophilus somnus 2336 cell division protein FtsB YP_001783850.1 584424 R 228400 CDS YP_001783851.1 170718655 6108298 complement(584715..585191) 1 NC_010519.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 585191 greB 6108298 greB Haemophilus somnus 2336 transcription elongation factor GreB YP_001783851.1 584715 R 228400 CDS YP_001783852.1 170718656 6108299 585371..587674 1 NC_010519.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: hso:HS_1493 transcription accessory protein, RNA-binding protein containing S1 domain; RNA-binding S1 domain-containing protein 587674 6108299 HSM_0508 Haemophilus somnus 2336 RNA-binding S1 domain-containing protein YP_001783852.1 585371 D 228400 CDS YP_001783853.1 170718657 6108300 587741..589057 1 NC_010519.1 PFAM: branched-chain amino acid ABC transporterer II carrier protein; KEGG: hso:HS_1492 branched-chain amino acid carrier protein; branched-chain amino acid ABC transporterer II carrier protein 589057 6108300 HSM_0509 Haemophilus somnus 2336 branched-chain amino acid ABC transporterer II carrier protein YP_001783853.1 587741 D 228400 CDS YP_001783854.1 170718659 6108301 complement(589095..589676) 1 NC_010519.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 589676 6108301 HSM_0510 Haemophilus somnus 2336 DNA uptake protein YP_001783854.1 589095 R 228400 CDS YP_001783855.1 170718660 6108303 complement(589769..590467) 1 NC_010519.1 KEGG: hso:HS_1490 competence protein; competence protein 590467 6108303 HSM_0511 Haemophilus somnus 2336 competence protein YP_001783855.1 589769 R 228400 CDS YP_001783856.1 170718661 6108304 590614..591426 1 NC_010519.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: hso:HS_1489 Cof protein; cof family hydrolase 591426 6108304 HSM_0512 Haemophilus somnus 2336 cof family hydrolase YP_001783856.1 590614 D 228400 CDS YP_001783857.1 170718662 6108305 591558..592598 1 NC_010519.1 PFAM: aminodeoxychorismate lyase; KEGG: hso:HS_1488 hypothetical protein; aminodeoxychorismate lyase 592598 6108305 HSM_0513 Haemophilus somnus 2336 aminodeoxychorismate lyase YP_001783857.1 591558 D 228400 CDS YP_001783858.1 170718663 6108306 592608..593240 1 NC_010519.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 593240 tmk 6108306 tmk Haemophilus somnus 2336 thymidylate kinase YP_001783858.1 592608 D 228400 CDS YP_001783859.1 170718664 6108307 593164..594222 1 NC_010519.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the subunit beta on the DNA; DNA polymerase III subunit delta' 594222 6108307 HSM_0515 Haemophilus somnus 2336 DNA polymerase III subunit delta' YP_001783859.1 593164 D 228400 CDS YP_001783860.1 170718665 6108308 594231..595013 1 NC_010519.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: hso:HS_1485 conserved hypothetical protein; TatD family hydrolase 595013 6108308 HSM_0516 Haemophilus somnus 2336 TatD family hydrolase YP_001783860.1 594231 D 228400 CDS YP_001783861.1 170718666 6108309 595041..595568 1 NC_010519.1 PFAM: protein of unknown function DUF1523; KEGG: hso:HS_1484 hypothetical protein; hypothetical protein 595568 6108309 HSM_0517 Haemophilus somnus 2336 hypothetical protein YP_001783861.1 595041 D 228400 CDS YP_001783862.1 170718667 6108310 595629..596918 1 NC_010519.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: hso:HS_1483 hypothetical protein; hypothetical protein 596918 6108310 HSM_0518 Haemophilus somnus 2336 hypothetical protein YP_001783862.1 595629 D 228400 CDS YP_001783863.1 170718668 6108311 complement(597062..597505) 1 NC_010519.1 KEGG: hso:HS_1482 hypothetical protein; hypothetical protein 597505 6108311 HSM_0519 Haemophilus somnus 2336 hypothetical protein YP_001783863.1 597062 R 228400 CDS YP_001783864.1 170718670 6108312 complement(597527..598132) 1 NC_010519.1 KEGG: hso:HS_1481 hypothetical protein; hypothetical protein 598132 6108312 HSM_0520 Haemophilus somnus 2336 hypothetical protein YP_001783864.1 597527 R 228400 CDS YP_001783865.1 170718671 6108314 complement(598461..599030) 1 NC_010519.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: hso:HS_1480 conserved hypothetical protein; GPR1/FUN34/yaaH family protein 599030 6108314 HSM_0521 Haemophilus somnus 2336 GPR1/FUN34/yaaH family protein YP_001783865.1 598461 R 228400 CDS YP_001783866.1 170718672 6108315 599470..600672 1 NC_010519.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 600672 6108315 HSM_0522 Haemophilus somnus 2336 bicyclomycin/multidrug efflux system protein YP_001783866.1 599470 D 228400 CDS YP_001783867.1 170718673 6108316 600682..600912 1 NC_010519.1 KEGG: hso:HS_1478 hypothetical protein; hypothetical protein 600912 6108316 HSM_0523 Haemophilus somnus 2336 hypothetical protein YP_001783867.1 600682 D 228400 CDS YP_001783868.1 170718674 6108317 complement(600962..602470) 1 NC_010519.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 602470 lysS 6108317 lysS Haemophilus somnus 2336 lysyl-tRNA synthetase YP_001783868.1 600962 R 228400 CDS YP_001783869.1 170718675 6108318 complement(602547..603416) 1 NC_010519.1 TIGRFAM: peptide chain release factor 2; PFAM: class I peptide chain release factor; PCRF domain protein; KEGG: msu:MS1542 protein chain release factor B; peptide chain release factor 2 603416 6108318 HSM_0525 Haemophilus somnus 2336 peptide chain release factor 2 YP_001783869.1 602547 R 228400 CDS YP_001783870.1 170718676 6108319 603776..604471 1 NC_010519.1 KEGG: hso:HS_1475 thiol:disulfide interchange protein; thiol:disulfide interchange protein 604471 6108319 HSM_0526 Haemophilus somnus 2336 thiol:disulfide interchange protein YP_001783870.1 603776 D 228400 CDS YP_001783871.1 170718677 6108320 604464..606185 1 NC_010519.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: hso:HS_1474 single-strand DNA-specific exonuclease; single-stranded-DNA-specific exonuclease RecJ 606185 6108320 HSM_0527 Haemophilus somnus 2336 single-stranded-DNA-specific exonuclease RecJ YP_001783871.1 604464 D 228400 CDS YP_001783872.1 170718678 6108321 606234..606383 1 NC_010519.1 KEGG: hit:NTHI1387 hypothetical protein; hypothetical protein 606383 6108321 HSM_0528 Haemophilus somnus 2336 hypothetical protein YP_001783872.1 606234 D 228400 CDS YP_001783873.1 170718679 6108322 606380..607069 1 NC_010519.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 607069 6108322 HSM_0529 Haemophilus somnus 2336 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_001783873.1 606380 D 228400 CDS YP_001783874.1 170718681 6108323 607181..607300 1 NC_010519.1 KEGG: hin:HI1720 hypothetical protein; hypothetical protein 607300 6108323 HSM_0530 Haemophilus somnus 2336 hypothetical protein YP_001783874.1 607181 D 228400 CDS YP_001783875.1 170718682 6108325 607402..607560 1 NC_010519.1 KEGG: hin:HI1721 transposase; transposase 607560 6108325 HSM_0531 Haemophilus somnus 2336 transposase YP_001783875.1 607402 D 228400 CDS YP_001783876.1 170718683 6108326 607593..607736 1 NC_010519.1 KEGG: hin:HI1721 transposase; transposase 607736 6108326 HSM_0532 Haemophilus somnus 2336 transposase YP_001783876.1 607593 D 228400 CDS YP_001783877.1 170718684 6108327 complement(607788..608000) 1 NC_010519.1 PFAM: ribosomal protein L31; KEGG: hso:HS_1472 50S ribosomal protein L31; 50S ribosomal protein L31 608000 6108327 HSM_0533 Haemophilus somnus 2336 50S ribosomal protein L31 YP_001783877.1 607788 R 228400 CDS YP_001783878.1 170718685 6108328 complement(608194..609852) 1 NC_010519.1 TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein; KEGG: hso:HS_1470 conserved hypothetical protein; hypothetical protein 609852 6108328 HSM_0534 Haemophilus somnus 2336 hypothetical protein YP_001783878.1 608194 R 228400 CDS YP_001783879.1 170718686 6108330 612131..614257 1 NC_010519.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 614257 6108330 HSM_0537 Haemophilus somnus 2336 anaerobic ribonucleoside triphosphate reductase YP_001783879.1 612131 D 228400 CDS YP_001783880.1 170718687 6108331 614273..614740 1 NC_010519.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 614740 nrdG 6108331 nrdG Haemophilus somnus 2336 anaerobic ribonucleotide reductase-activating protein YP_001783880.1 614273 D 228400 CDS YP_001783881.1 170718688 6108332 complement(615013..616740) 1 NC_010519.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; SMART: HNH nuclease; KEGG: pau:PA14_07480 reverse transcriptase; RNA-directed DNA polymerase 616740 6108332 HSM_0539 Haemophilus somnus 2336 RNA-directed DNA polymerase YP_001783881.1 615013 R 228400 CDS YP_001783882.1 170718690 6108333 complement(618335..619339) 1 NC_010519.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: hso:HS_1466 glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase 619339 6108333 HSM_0540 Haemophilus somnus 2336 glyceraldehyde-3-phosphate dehydrogenase YP_001783882.1 618335 R 228400 CDS YP_001783883.1 170718691 6108335 complement(619572..619721) 1 NC_010519.1 KEGG: hso:HS_1465 hypothetical protein; hypothetical protein 619721 6108335 HSM_0541 Haemophilus somnus 2336 hypothetical protein YP_001783883.1 619572 R 228400 CDS YP_001783884.1 170718692 6108336 619796..620599 1 NC_010519.1 PFAM: Choline/ethanolamine kinase; KEGG: hso:HS_1461 LicA protein; choline/ethanolamine kinase 620599 6108336 HSM_0542 Haemophilus somnus 2336 choline/ethanolamine kinase YP_001783884.1 619796 D 228400 CDS YP_001783885.1 170718693 6108337 620586..621518 1 NC_010519.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: hso:HS_1460 lic-1 operon protein (LicB); hypothetical protein 621518 6108337 HSM_0543 Haemophilus somnus 2336 hypothetical protein YP_001783885.1 620586 D 228400 CDS YP_001783886.1 170718694 6108338 621515..622213 1 NC_010519.1 KEGG: hso:HS_1459 LicC protein; LicC protein 622213 6108338 HSM_0544 Haemophilus somnus 2336 LicC protein YP_001783886.1 621515 D 228400 CDS YP_001783887.1 170718695 6108339 622215..623015 1 NC_010519.1 PFAM: LicD family protein; KEGG: hso:HS_1458 lipopolysaccharide choline phosphotransferase; LicD family protein 623015 6108339 HSM_0545 Haemophilus somnus 2336 LicD family protein YP_001783887.1 622215 D 228400 CDS YP_001783888.1 170718696 6108340 623124..623750 1 NC_010519.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 623750 gmk 6108340 gmk Haemophilus somnus 2336 guanylate kinase YP_001783888.1 623124 D 228400 CDS YP_001783889.1 170718697 6108341 623805..624077 1 NC_010519.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and subunit alphas; DNA-directed RNA polymerase subunit omega 624077 rpoZ 6108341 rpoZ Haemophilus somnus 2336 DNA-directed RNA polymerase subunit omega YP_001783889.1 623805 D 228400 CDS YP_001783890.1 170718698 6108342 624158..626281 1 NC_010519.1 KEGG: hso:HS_1455 guanosine-3'5'-bis(diphosphate) 3'-pyrophosphohydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region; (p)ppGpp synthetase I SpoT/RelA 626281 6108342 HSM_0548 Haemophilus somnus 2336 (p)ppGpp synthetase I SpoT/RelA YP_001783890.1 624158 D 228400 CDS YP_001783891.1 170718699 6108343 626281..628362 1 NC_010519.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 628362 6108343 HSM_0549 Haemophilus somnus 2336 ATP-dependent DNA helicase RecG YP_001783891.1 626281 D 228400 CDS YP_001783892.1 170718701 6108344 628432..629235 1 NC_010519.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 629235 6108344 HSM_0550 Haemophilus somnus 2336 glutamate racemase YP_001783892.1 628432 D 228400 CDS YP_001783893.1 170718702 6108863 635838..636359 1 NC_010519.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: hso:HS_1567 permease, drug/metabolite transporter superfamily; hypothetical protein 636359 6108863 HSM_0551 Haemophilus somnus 2336 hypothetical protein YP_001783893.1 635838 D 228400 CDS YP_001783894.1 170718703 6108347 636597..637931 1 NC_010519.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 637931 6108347 HSM_0552 Haemophilus somnus 2336 anaerobic C4-dicarboxylate transporter YP_001783894.1 636597 D 228400 CDS YP_001783895.1 170718704 6108348 638435..642463 1 NC_010519.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; subunit beta is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 642463 rpoB 6108348 rpoB Haemophilus somnus 2336 DNA-directed RNA polymerase subunit beta YP_001783895.1 638435 D 228400 CDS YP_001783896.1 170718705 6108349 642554..646816 1 NC_010519.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 646816 6108349 HSM_0554 Haemophilus somnus 2336 DNA-directed RNA polymerase subunit beta' YP_001783896.1 642554 D 228400 CDS YP_001783897.1 170718706 6108350 647153..648004 1 NC_010519.1 involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR 648004 6108350 HSM_0555 Haemophilus somnus 2336 DNA-binding transcriptional repressor RpiR YP_001783897.1 647153 D 228400 CDS YP_001783898.1 170718707 6108351 648199..649134 1 NC_010519.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ecj:JW4049 D-allose transporter subunit; D-allose transporter subunit 649134 6108351 HSM_0556 Haemophilus somnus 2336 D-allose transporter subunit YP_001783898.1 648199 D 228400 CDS YP_001783899.1 170718708 6108352 649182..650717 1 NC_010519.1 with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein 650717 6108352 HSM_0557 Haemophilus somnus 2336 D-allose transporter ATP-binding protein YP_001783899.1 649182 D 228400 CDS YP_001783900.1 170718709 6108353 650717..651667 1 NC_010519.1 PFAM: inner-membrane translocator; KEGG: ecc:c5092 D-allose transporter permease alsC; D-allose transporter subunit 651667 6108353 HSM_0558 Haemophilus somnus 2336 D-allose transporter subunit YP_001783900.1 650717 D 228400 CDS YP_001783901.1 170718710 6108354 651685..652371 1 NC_010519.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: ecj:JW4046 allulose-6-phosphate 3-epimerase; allulose-6-phosphate 3-epimerase 652371 6108354 HSM_0559 Haemophilus somnus 2336 allulose-6-phosphate 3-epimerase YP_001783901.1 651685 D 228400 CDS YP_001783902.1 170718712 6108355 652371..653261 1 NC_010519.1 PFAM: ROK family protein; KEGG: ecp:ECP_4326 D-allose kinase; D-allose kinase 653261 6108355 HSM_0560 Haemophilus somnus 2336 D-allose kinase YP_001783902.1 652371 D 228400 CDS YP_001783903.1 170718713 6108357 653261..653734 1 NC_010519.1 TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: ribose/galactose isomerase; KEGG: llc:LACR_1638 galactose 6-phosphate isomerase; RpiB/LacA/LacB family sugar-phosphate isomerase 653734 6108357 HSM_0561 Haemophilus somnus 2336 RpiB/LacA/LacB family sugar-phosphate isomerase YP_001783903.1 653261 D 228400 CDS YP_001783904.1 170718714 6108358 complement(654233..655564) 1 NC_010519.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 655564 hslU 6108358 hslU Haemophilus somnus 2336 ATP-dependent protease ATP-binding subunit HslU YP_001783904.1 654233 R 228400 CDS YP_001783905.1 170718715 6108359 complement(655582..656109) 1 NC_010519.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 656109 6108359 HSM_0563 Haemophilus somnus 2336 ATP-dependent protease peptidase subunit YP_001783905.1 655582 R 228400 CDS YP_001783906.1 170718716 6108360 656396..657460 1 NC_010519.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 657460 hemE 6108360 hemE Haemophilus somnus 2336 uroporphyrinogen decarboxylase YP_001783906.1 656396 D 228400 CDS YP_001783907.1 170718717 6108361 657477..658067 1 NC_010519.1 PFAM: protein of unknown function DUF416; KEGG: hso:HS_1539 hypothetical protein; hypothetical protein 658067 6108361 HSM_0565 Haemophilus somnus 2336 hypothetical protein YP_001783907.1 657477 D 228400 CDS YP_001783908.1 170718718 6108362 658226..658501 1 NC_010519.1 PFAM: histone family protein DNA-binding protein; KEGG: hso:HS_1538 DNA-binding protein HU; histone family protein DNA-binding protein 658501 6108362 HSM_0566 Haemophilus somnus 2336 histone family protein DNA-binding protein YP_001783908.1 658226 D 228400 CDS YP_001783909.1 170718719 6108363 658663..659445 1 NC_010519.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: hso:HS_1537 transcriptional regulator, DeoR family; DeoR family transcriptional regulator 659445 6108363 HSM_0567 Haemophilus somnus 2336 DeoR family transcriptional regulator YP_001783909.1 658663 D 228400 CDS YP_001783910.1 170718720 6108364 659471..661303 1 NC_010519.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 661303 6108364 HSM_0568 Haemophilus somnus 2336 glucosamine--fructose-6-phosphate aminotransferase YP_001783910.1 659471 D 228400 CDS YP_001783911.1 170718721 6108365 complement(661375..662205) 1 NC_010519.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: hso:HS_1535 outer membrane lipoprotein 1 precursor; YaeC family lipoprotein 662205 6108365 HSM_0569 Haemophilus somnus 2336 YaeC family lipoprotein YP_001783911.1 661375 R 228400 CDS YP_001783912.1 170718723 6108366 complement(662241..662930) 1 NC_010519.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_1534 D-methionine ABC transporter permease; binding-protein-dependent transporters inner membrane component 662930 6108366 HSM_0570 Haemophilus somnus 2336 binding-protein-dependent transporters inner membrane component YP_001783912.1 662241 R 228400 CDS YP_001783913.1 170718724 6108368 complement(662920..663957) 1 NC_010519.1 part of the metNIQ transporter for methionine; DL-methionine transporter ATP-binding subunit 663957 metN 6108368 metN Haemophilus somnus 2336 DL-methionine transporter ATP-binding subunit YP_001783913.1 662920 R 228400 CDS YP_001783914.1 170718725 6108369 664112..664666 1 NC_010519.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 664666 6108369 HSM_0572 Haemophilus somnus 2336 D,D-heptose 1,7-bisphosphate phosphatase YP_001783914.1 664112 D 228400 CDS YP_001783915.1 170718726 6108370 complement(664818..665894) 1 NC_010519.1 PFAM: protein of unknown function DUF1603; KEGG: hpy:HP1471 type IIS restriction enzyme R protein; hypothetical protein 665894 6108370 HSM_0573 Haemophilus somnus 2336 hypothetical protein YP_001783915.1 664818 R 228400 CDS YP_001783916.1 170718727 6108372 complement(668254..669396) 1 NC_010519.1 PFAM: glycerate kinase; KEGG: hso:HS_1524 glycerate kinase; glycerate kinase 669396 6108372 HSM_0576 Haemophilus somnus 2336 glycerate kinase YP_001783916.1 668254 R 228400 CDS YP_001783917.1 170718728 6108373 complement(669422..670681) 1 NC_010519.1 PFAM: gluconate transporter; citrate transporter; KEGG: hit:NTHI0171 hypothetical protein; citrate transporter 670681 6108373 HSM_0577 Haemophilus somnus 2336 citrate transporter YP_001783917.1 669422 R 228400 CDS YP_001783918.1 170718729 6108374 complement(670809..671927) 1 NC_010519.1 PFAM: sugar diacid recognition domain protein; KEGG: hso:HS_1521 sugar diacid utilization regulator; CdaR family transcriptional regulator 671927 6108374 HSM_0578 Haemophilus somnus 2336 CdaR family transcriptional regulator YP_001783918.1 670809 R 228400 CDS YP_001783919.1 170718730 6108867 complement(677604..677888) 1 NC_010519.1 KEGG: hso:HS_1452 hypothetical protein; hypothetical protein 677888 6108867 HSM_0579 Haemophilus somnus 2336 hypothetical protein YP_001783919.1 677604 R 228400 CDS YP_001783920.1 170718732 6108376 complement(678110..678757) 1 NC_010519.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 678757 6108376 HSM_0580 Haemophilus somnus 2336 L-fuculose phosphate aldolase YP_001783920.1 678110 R 228400 CDS YP_001783921.1 170718733 6108378 complement(678771..679205) 1 NC_010519.1 PFAM: RbsD or FucU transport; KEGG: hso:HS_1450 fucose operon FucU protein; transport protein RbsD/FucU 679205 6108378 HSM_0581 Haemophilus somnus 2336 transport protein RbsD/FucU YP_001783921.1 678771 R 228400 CDS YP_001783922.1 170718734 6108379 complement(679199..680656) 1 NC_010519.1 TIGRFAM: L-fuculokinase; PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_1449 L-fuculokinase; L-fuculokinase 680656 6108379 HSM_0582 Haemophilus somnus 2336 L-fuculokinase YP_001783922.1 679199 R 228400 CDS YP_001783923.1 170718735 6108380 complement(680738..682504) 1 NC_010519.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 682504 fucI 6108380 fucI Haemophilus somnus 2336 L-fucose isomerase YP_001783923.1 680738 R 228400 CDS YP_001783924.1 170718736 6108381 complement(682700..683995) 1 NC_010519.1 TIGRFAM: L-fucose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_1447 L-fucose permease; L-fucose transporter 683995 6108381 HSM_0584 Haemophilus somnus 2336 L-fucose transporter YP_001783924.1 682700 R 228400 CDS YP_001783925.1 170718737 6108382 complement(684250..685002) 1 NC_010519.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: hso:HS_1446 L-fucose operon activator; DeoR family transcriptional regulator 685002 6108382 HSM_0585 Haemophilus somnus 2336 DeoR family transcriptional regulator YP_001783925.1 684250 R 228400 CDS YP_001783926.1 170718738 6108383 685238..685921 1 NC_010519.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 685921 gpmA 6108383 gpmA Haemophilus somnus 2336 phosphoglyceromutase YP_001783926.1 685238 D 228400 CDS YP_001783927.1 170718739 6108384 686061..687392 1 NC_010519.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; 30S ribosomal protein S12 methylthiotransferase 687392 rimO 6108384 rimO Haemophilus somnus 2336 30S ribosomal protein S12 methylthiotransferase YP_001783927.1 686061 D 228400 CDS YP_001783928.1 170718740 6108385 687484..688716 1 NC_010519.1 PFAM: peptidase M23B; KEGG: hso:HS_1443 hypothetical protein; peptidase M23B 688716 6108385 HSM_0588 Haemophilus somnus 2336 peptidase M23B YP_001783928.1 687484 D 228400 CDS YP_001783929.1 170718741 6108386 688718..689575 1 NC_010519.1 PFAM: protein of unknown function DUF610 YibQ; KEGG: hso:HS_1442 hypothetical protein; hypothetical protein 689575 6108386 HSM_0589 Haemophilus somnus 2336 hypothetical protein YP_001783929.1 688718 D 228400 CDS YP_001783930.1 170718743 6108387 complement(689630..690082) 1 NC_010519.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 690082 6108387 HSM_0590 Haemophilus somnus 2336 DNA-binding transcriptional regulator AsnC YP_001783930.1 689630 R 228400 CDS YP_001783931.1 170718744 6108389 690266..691258 1 NC_010519.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 691258 6108389 HSM_0591 Haemophilus somnus 2336 asparagine synthetase AsnA YP_001783931.1 690266 D 228400 CDS YP_001783932.1 170718745 6108390 691375..692097 1 NC_010519.1 PFAM: MgtC/SapB transporter; KEGG: hso:HS_1439 conserved hypothetical protein; MgtC/SapB transporter 692097 6108390 HSM_0592 Haemophilus somnus 2336 MgtC/SapB transporter YP_001783932.1 691375 D 228400 CDS YP_001783933.1 170718746 6108391 complement(692750..693163) 1 NC_010519.1 hypothetical protein 693163 6108391 HSM_0593 Haemophilus somnus 2336 hypothetical protein YP_001783933.1 692750 R 228400 CDS YP_001783934.1 170718747 6108392 complement(693192..694253) 1 NC_010519.1 KEGG: hdu:HD1616 transposase; transposase 694253 6108392 HSM_0594 Haemophilus somnus 2336 transposase YP_001783934.1 693192 R 228400 CDS YP_001783935.1 170718748 6108393 complement(694739..695035) 1 NC_010519.1 KEGG: ngo:NGO0366 hypothetical protein; hypothetical protein 695035 6108393 HSM_0595 Haemophilus somnus 2336 hypothetical protein YP_001783935.1 694739 R 228400 CDS YP_001783936.1 170718749 6108394 695021..696139 1 NC_010519.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: ngo:NGO0365 site-specific DNA-methyltransferase M.NgoVII; DNA-cytosine methyltransferase 696139 6108394 HSM_0596 Haemophilus somnus 2336 DNA-cytosine methyltransferase YP_001783936.1 695021 D 228400 CDS YP_001783937.1 170718750 6108395 696139..697188 1 NC_010519.1 KEGG: ngo:NGO0364 restriction endonuclease R.NgoVII; type II site-specific deoxyribonuclease 697188 6108395 HSM_0597 Haemophilus somnus 2336 type II site-specific deoxyribonuclease YP_001783937.1 696139 D 228400 CDS YP_001783938.1 170718751 6108396 697189..699078 1 NC_010519.1 KEGG: ngo:NGO0363 stress-sensitive restriction system protein; stress-sensitive restriction system protein 699078 6108396 HSM_0598 Haemophilus somnus 2336 stress-sensitive restriction system protein YP_001783938.1 697189 D 228400 CDS YP_001783939.1 170718752 6108397 complement(699183..699461) 1 NC_010519.1 PFAM: helix-turn-helix domain protein; KEGG: hdu:HD1613 hypothetical protein; XRE family transcriptional regulator 699461 6108397 HSM_0599 Haemophilus somnus 2336 XRE family transcriptional regulator YP_001783939.1 699183 R 228400 CDS YP_001783940.1 170718755 6108401 700602..701042 1 NC_010519.1 KEGG: hdu:HD1697 hypothetical protein; hypothetical protein 701042 6108401 HSM_0602 Haemophilus somnus 2336 hypothetical protein YP_001783940.1 700602 D 228400 CDS YP_001783941.1 170718756 6108402 complement(701055..701204) 1 NC_010519.1 hypothetical protein 701204 6108402 HSM_0603 Haemophilus somnus 2336 hypothetical protein YP_001783941.1 701055 R 228400 CDS YP_001783942.1 170718757 6108403 701737..702114 1 NC_010519.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 702114 rpsF 6108403 rpsF Haemophilus somnus 2336 30S ribosomal protein S6 YP_001783942.1 701737 D 228400 CDS YP_001783943.1 170718758 6108404 702101..702427 1 NC_010519.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 702427 6108404 HSM_0605 Haemophilus somnus 2336 primosomal replication protein N YP_001783943.1 702101 D 228400 CDS YP_001783944.1 170718759 6108405 702440..702667 1 NC_010519.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 702667 rpsR 6108405 rpsR Haemophilus somnus 2336 30S ribosomal protein S18 YP_001783944.1 702440 D 228400 CDS YP_001783945.1 170718760 6108406 702686..703135 1 NC_010519.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 703135 rplI 6108406 rplI Haemophilus somnus 2336 50S ribosomal protein L9 YP_001783945.1 702686 D 228400 CDS YP_001783946.1 170718761 6108407 703668..704855 1 NC_010519.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: hso:HS_1434 N-acyl-L-amino acid amidohydrolase; amidohydrolase 704855 6108407 HSM_0608 Haemophilus somnus 2336 amidohydrolase YP_001783946.1 703668 D 228400 CDS YP_001783947.1 170718762 6108408 705119..706027 1 NC_010519.1 PFAM: protein of unknown function DUF511; KEGG: pin:Ping_0238 hypothetical protein DUF511; hypothetical protein 706027 6108408 HSM_0609 Haemophilus somnus 2336 hypothetical protein YP_001783947.1 705119 D 228400 CDS YP_001783948.1 170718764 6108409 706031..709363 1 NC_010519.1 PFAM: N-6 DNA methylase; KEGG: cjr:CJE1195 type II restriction-modification enzyme; N-6 DNA methylase 709363 6108409 HSM_0610 Haemophilus somnus 2336 N-6 DNA methylase YP_001783948.1 706031 D 228400 CDS YP_001783949.1 170718765 6108411 709456..709941 1 NC_010519.1 KEGG: cje:Cj1051c restriction modification enzyme; restriction modification enzyme 709941 6108411 HSM_0611 Haemophilus somnus 2336 restriction modification enzyme YP_001783949.1 709456 D 228400 CDS YP_001783950.1 170718766 6108412 710510..711667 1 NC_010519.1 PFAM: sodium/calcium exchanger membrane region; KEGG: hso:HS_0343 calcium/proton antiporter; sodium/calcium exchanger membrane region 711667 6108412 HSM_0612 Haemophilus somnus 2336 sodium/calcium exchanger membrane region YP_001783950.1 710510 D 228400 CDS YP_001783951.1 170718767 6108413 711739..712743 1 NC_010519.1 PFAM: conserved hypothetical protein 698; KEGG: hso:HS_0344 membrane protein; hypothetical protein 712743 6108413 HSM_0613 Haemophilus somnus 2336 hypothetical protein YP_001783951.1 711739 D 228400 CDS YP_001783952.1 170718768 6108414 712760..713872 1 NC_010519.1 PFAM: PhoH family protein; KEGG: hso:HS_0345 PhoH-like ATP-binding protein; PhoH family protein 713872 6108414 HSM_0614 Haemophilus somnus 2336 PhoH family protein YP_001783952.1 712760 D 228400 CDS YP_001783953.1 170718769 6108415 713894..714358 1 NC_010519.1 PFAM: protein of unknown function UPF0054; KEGG: hso:HS_0346 conserved hypothetical protein; hypothetical protein 714358 6108415 HSM_0615 Haemophilus somnus 2336 hypothetical protein YP_001783953.1 713894 D 228400 CDS YP_001783954.1 170718770 6108416 714369..716300 1 NC_010519.1 PFAM: protein of unknown function DUF699 ATPase KEGG: hso:HS_0347 acetyltransferase; hypothetical protein 716300 6108416 HSM_0616 Haemophilus somnus 2336 hypothetical protein YP_001783954.1 714369 D 228400 CDS YP_001783955.1 170718771 6108417 716333..716506 1 NC_010519.1 KEGG: hso:HS_0347a hypothetical protein; hypothetical protein 716506 6108417 HSM_0617 Haemophilus somnus 2336 hypothetical protein YP_001783955.1 716333 D 228400 CDS YP_001783956.1 170718772 6108418 716651..718234 1 NC_010519.1 PFAM: carbon starvation protein CstA; KEGG: hso:HS_0348 carbon starvation protein A; carbon starvation protein CstA 718234 6108418 HSM_0618 Haemophilus somnus 2336 carbon starvation protein CstA YP_001783956.1 716651 D 228400 CDS YP_001783957.1 170718773 6108419 718457..718915 1 NC_010519.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 718915 6108419 HSM_0619 Haemophilus somnus 2336 cell division protein MraZ YP_001783957.1 718457 D 228400 CDS YP_001783958.1 170718775 6108420 719027..719992 1 NC_010519.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: hso:HS_0350 S-adenosyl-methyltransferase; S-adenosyl-methyltransferase MraW 719992 mraW 6108420 mraW Haemophilus somnus 2336 S-adenosyl-methyltransferase MraW YP_001783958.1 719027 D 228400 CDS YP_001783959.1 170718776 6108422 719992..720312 1 NC_010519.1 PFAM: cell division protein FtsL; KEGG: hso:HS_0351 cell division protein; cell division protein FtsL 720312 6108422 HSM_0621 Haemophilus somnus 2336 cell division protein FtsL YP_001783959.1 719992 D 228400 CDS YP_001783960.1 170718777 6108423 720337..722136 1 NC_010519.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: hso:HS_0352 peptidoglycan glycosyltransferase (peptidoglycan synthetase); peptidoglycan glycosyltransferase 722136 6108423 HSM_0622 Haemophilus somnus 2336 peptidoglycan glycosyltransferase YP_001783960.1 720337 D 228400 CDS YP_001783961.1 170718778 6108424 722152..723639 1 NC_010519.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 723639 murE 6108424 murE Haemophilus somnus 2336 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_001783961.1 722152 D 228400 CDS YP_001783962.1 170718779 6108425 723720..725111 1 NC_010519.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: hso:HS_0354 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (MurF synthetase); UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase 725111 6108425 HSM_0624 Haemophilus somnus 2336 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase YP_001783962.1 723720 D 228400 CDS YP_001783963.1 170718780 6108426 725105..726190 1 NC_010519.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 726190 mraY 6108426 mraY Haemophilus somnus 2336 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001783963.1 725105 D 228400 CDS YP_001783964.1 170718781 6108427 726199..727509 1 NC_010519.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 727509 murD 6108427 murD Haemophilus somnus 2336 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_001783964.1 726199 D 228400 CDS YP_001783965.1 170718782 6108428 727523..728707 1 NC_010519.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: hso:HS_0357 cell division protein; cell division protein FtsW 728707 6108428 HSM_0627 Haemophilus somnus 2336 cell division protein FtsW YP_001783965.1 727523 D 228400 CDS YP_001783966.1 170718783 6108429 728723..729796 1 NC_010519.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 729796 murG 6108429 murG Haemophilus somnus 2336 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_001783966.1 728723 D 228400 CDS YP_001783967.1 170718784 6108430 729850..731280 1 NC_010519.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 731280 murC 6108430 murC Haemophilus somnus 2336 UDP-N-acetylmuramate--L-alanine ligase YP_001783967.1 729850 D 228400 CDS YP_001783968.1 170718786 6108431 731325..732251 1 NC_010519.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 732251 ddl 6108431 ddl Haemophilus somnus 2336 D-alanine--D-alanine ligase YP_001783968.1 731325 D 228400 CDS YP_001783969.1 170718787 6108433 732252..733025 1 NC_010519.1 PFAM: cell division protein FtsQ; polypeptide-transport-associated domain protein FtsQ-type; KEGG: hso:HS_0361 cell division protein; cell division protein FtsQ 733025 6108433 HSM_0631 Haemophilus somnus 2336 cell division protein FtsQ YP_001783969.1 732252 D 228400 CDS YP_001783970.1 170718788 6108434 733056..734330 1 NC_010519.1 PFAM: cell division protein FtsA; KEGG: hso:HS_0362 ATP-binding cell division protein; cell division protein FtsA 734330 6108434 HSM_0632 Haemophilus somnus 2336 cell division protein FtsA YP_001783970.1 733056 D 228400 CDS YP_001783971.1 170718789 6108435 734417..735631 1 NC_010519.1 TIGRFAM: cell division protein FtsZ; PFAM: Tubulin/FtsZ GTPase; Tubulin/FtsZ domain protein; KEGG: hso:HS_0363 cell division protein; cell division protein FtsZ 735631 6108435 HSM_0633 Haemophilus somnus 2336 cell division protein FtsZ YP_001783971.1 734417 D 228400 CDS YP_001783972.1 170718790 6108436 735672..736589 1 NC_010519.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 736589 lpxC 6108436 lpxC Haemophilus somnus 2336 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_001783972.1 735672 D 228400 CDS YP_001783973.1 170718791 6108437 736713..737870 1 NC_010519.1 TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; chorismate mutase; KEGG: hso:HS_0365 bifunctional P-protein/chorismate mutase; chorismate mutase 737870 6108437 HSM_0635 Haemophilus somnus 2336 chorismate mutase YP_001783973.1 736713 D 228400 CDS YP_001783974.1 170718792 6108438 complement(737932..738720) 1 NC_010519.1 PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: hso:HS_0366 DNA uptake lipoprotein; hypothetical protein 738720 6108438 HSM_0636 Haemophilus somnus 2336 hypothetical protein YP_001783974.1 737932 R 228400 CDS YP_001783975.1 170718793 6108439 738821..739795 1 NC_010519.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 739795 rluD 6108439 rluD Haemophilus somnus 2336 23S rRNA pseudouridine synthase D YP_001783975.1 738821 D 228400 CDS YP_001783976.1 170718794 6108440 739797..740537 1 NC_010519.1 PFAM: protein of unknown function DUF152; KEGG: hso:HS_0368 conserved hypothetical protein; hypothetical protein 740537 6108440 HSM_0638 Haemophilus somnus 2336 hypothetical protein YP_001783976.1 739797 D 228400 CDS YP_001783977.1 170718795 6108441 complement(740590..741540) 1 NC_010519.1 TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; KEGG: hso:HS_0369 cysteine synthase; cysteine synthase A 741540 6108441 HSM_0639 Haemophilus somnus 2336 cysteine synthase A YP_001783977.1 740590 R 228400 CDS YP_001783978.1 170718797 6108442 complement(741659..742432) 1 NC_010519.1 role in sulfur assimilation; sulfate transporter CysZ 742432 6108442 HSM_0640 Haemophilus somnus 2336 sulfate transporter CysZ YP_001783978.1 741659 R 228400 CDS YP_001783979.1 170718798 6108444 742592..743599 1 NC_010519.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 743599 6108444 HSM_0641 Haemophilus somnus 2336 cell division protein ZipA YP_001783979.1 742592 D 228400 CDS YP_001783980.1 170718799 6108445 744112..745782 1 NC_010519.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 745782 6108445 HSM_0642 Haemophilus somnus 2336 ABC transporter ATP-binding protein YP_001783980.1 744112 D 228400 CDS YP_001783981.1 170718800 6108446 745806..746348 1 NC_010519.1 KEGG: msu:MS1887 hypothetical protein; hypothetical protein 746348 6108446 HSM_0643 Haemophilus somnus 2336 hypothetical protein YP_001783981.1 745806 D 228400 CDS YP_001783982.1 170718801 6108447 complement(746757..747233) 1 NC_010519.1 PFAM: ABC transporter; KEGG: vpa:VPA1495 ABC transporter ATP-binding protein; ABC transporter 747233 6108447 HSM_0644 Haemophilus somnus 2336 ABC transporter YP_001783982.1 746757 R 228400 CDS YP_001783983.1 170718802 6108448 complement(747563..747808) 1 NC_010519.1 PFAM: peptidase S24 S26A and S26B; KEGG: mgm:Mmc1_2924 phage repressor; phage repressor 747808 6108448 HSM_0645 Haemophilus somnus 2336 phage repressor YP_001783983.1 747563 R 228400 CDS YP_001783984.1 170718803 6108449 complement(748000..748527) 1 NC_010519.1 hypothetical protein 748527 6108449 HSM_0646 Haemophilus somnus 2336 hypothetical protein YP_001783984.1 748000 R 228400 CDS YP_001783985.1 170718804 6108450 748861..750849 1 NC_010519.1 PFAM: Integrase catalytic region; MuA-transposase/repressor protein CI DNA-binding; transposase-like Mu; KEGG: ecs:ECs4945 phage transposase; transposase 750849 6108450 HSM_0647 Haemophilus somnus 2336 transposase YP_001783985.1 748861 D 228400 CDS YP_001783986.1 170718805 6108451 750853..751728 1 NC_010519.1 PFAM: helix-turn-helix domain protein; KEGG: nmc:NMC1048 phage transposase; helix-turn-helix domain-containing protein 751728 6108451 HSM_0648 Haemophilus somnus 2336 helix-turn-helix domain-containing protein YP_001783986.1 750853 D 228400 CDS YP_001783987.1 170718806 6108452 751951..752166 1 NC_010519.1 hypothetical protein 752166 6108452 HSM_0649 Haemophilus somnus 2336 hypothetical protein YP_001783987.1 751951 D 228400 CDS YP_001783988.1 170718808 6108453 752175..752369 1 NC_010519.1 hypothetical protein 752369 6108453 HSM_0650 Haemophilus somnus 2336 hypothetical protein YP_001783988.1 752175 D 228400 CDS YP_001783989.1 170718809 6108455 752606..753223 1 NC_010519.1 KEGG: hdu:HD0097 hypothetical protein; hypothetical protein 753223 6108455 HSM_0651 Haemophilus somnus 2336 hypothetical protein YP_001783989.1 752606 D 228400 CDS YP_001783990.1 170718810 6108456 753390..753710 1 NC_010519.1 hypothetical protein 753710 6108456 HSM_0652 Haemophilus somnus 2336 hypothetical protein YP_001783990.1 753390 D 228400 CDS YP_001783991.1 170718811 6108457 754070..754237 1 NC_010519.1 KEGG: hdu:HD0100 hypothetical protein; hypothetical protein 754237 6108457 HSM_0653 Haemophilus somnus 2336 hypothetical protein YP_001783991.1 754070 D 228400 CDS YP_001783992.1 170718812 6108458 754404..754796 1 NC_010519.1 hypothetical protein 754796 6108458 HSM_0654 Haemophilus somnus 2336 hypothetical protein YP_001783992.1 754404 D 228400 CDS YP_001783993.1 170718813 6108459 754904..755254 1 NC_010519.1 KEGG: hdu:HD0107 hypothetical protein; hypothetical protein 755254 6108459 HSM_0655 Haemophilus somnus 2336 hypothetical protein YP_001783993.1 754904 D 228400 CDS YP_001783994.1 170718814 6108460 755381..755755 1 NC_010519.1 KEGG: hdu:HD1519 hypothetical protein; hypothetical protein 755755 6108460 HSM_0656 Haemophilus somnus 2336 hypothetical protein YP_001783994.1 755381 D 228400 CDS YP_001783995.1 170718815 6108461 755742..756152 1 NC_010519.1 PFAM: protein of unknown function DUF1018; KEGG: hdu:HD0497 hypothetical protein; hypothetical protein 756152 6108461 HSM_0657 Haemophilus somnus 2336 hypothetical protein YP_001783995.1 755742 D 228400 CDS YP_001783996.1 170718816 6108462 756212..756706 1 NC_010519.1 hypothetical protein 756706 6108462 HSM_0658 Haemophilus somnus 2336 hypothetical protein YP_001783996.1 756212 D 228400 CDS YP_001783997.1 170718817 6108463 756891..757319 1 NC_010519.1 KEGG: hdu:HD0500 hypothetical protein; hypothetical protein 757319 6108463 HSM_0659 Haemophilus somnus 2336 hypothetical protein YP_001783997.1 756891 D 228400 CDS YP_001783998.1 170718819 6108464 757402..757938 1 NC_010519.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: Animal peptidoglycan recognition protein PGRP; KEGG: hdu:HD0112 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase 757938 6108464 HSM_0660 Haemophilus somnus 2336 N-acetylmuramoyl-L-alanine amidase YP_001783998.1 757402 D 228400 CDS YP_001783999.1 170718820 6108466 758081..758323 1 NC_010519.1 KEGG: hdu:HD0503 hypothetical protein; hypothetical protein 758323 6108466 HSM_0661 Haemophilus somnus 2336 hypothetical protein YP_001783999.1 758081 D 228400 CDS YP_001784000.1 170718821 6108467 758320..758574 1 NC_010519.1 hypothetical protein 758574 6108467 HSM_0662 Haemophilus somnus 2336 hypothetical protein YP_001784000.1 758320 D 228400 CDS YP_001784001.1 170718822 6108468 758685..758939 1 NC_010519.1 KEGG: nma:NMA1856 hypothetical protein; hypothetical protein 758939 6108468 HSM_0663 Haemophilus somnus 2336 hypothetical protein YP_001784001.1 758685 D 228400 CDS YP_001784002.1 170718823 6108469 758939..759193 1 NC_010519.1 KEGG: hdu:HD0507 hypothetical protein; hypothetical protein 759193 6108469 HSM_0664 Haemophilus somnus 2336 hypothetical protein YP_001784002.1 758939 D 228400 CDS YP_001784003.1 170718824 6108470 759194..759697 1 NC_010519.1 PFAM: protein of unknown function DUF1804; KEGG: hdu:HD0509 conserved DNA-binding protein; hypothetical protein 759697 6108470 HSM_0665 Haemophilus somnus 2336 hypothetical protein YP_001784003.1 759194 D 228400 CDS YP_001784004.1 170718825 6108471 759800..761443 1 NC_010519.1 TIGRFAM: phage uncharacterized protein; KEGG: nma:NMA1313 hypothetical protein; phage lprotein 761443 6108471 HSM_0666 Haemophilus somnus 2336 phage lprotein YP_001784004.1 759800 D 228400 CDS YP_001784005.1 170718826 6108472 761447..763105 1 NC_010519.1 PFAM: protein of unknown function DUF935; KEGG: hdu:HD0514 hypothetical protein; hypothetical protein 763105 6108472 HSM_0667 Haemophilus somnus 2336 hypothetical protein YP_001784005.1 761447 D 228400 CDS YP_001784006.1 170718827 6108473 763092..764366 1 NC_010519.1 TIGRFAM: phage head morphogenesis protein, SPP1 gp7 family; PFAM: phage head morphogenesis protein SPP1 gp7; KEGG: hdu:HD0515 hypothetical protein; SPP1 family phage head morphogenesis protein 764366 6108473 HSM_0668 Haemophilus somnus 2336 SPP1 family phage head morphogenesis protein YP_001784006.1 763092 D 228400 CDS YP_001784007.1 170718828 6108474 764940..765425 1 NC_010519.1 TIGRFAM: phage virion morphogenesis protein; PFAM: phage virion morphogenesis ( tail completion) protein; KEGG: hin:HI1568 G protein; phage virion morphogenesis protein 765425 6108474 HSM_0669 Haemophilus somnus 2336 phage virion morphogenesis protein YP_001784007.1 764940 D 228400 CDS YP_001784008.1 170718830 6108475 765686..766726 1 NC_010519.1 KEGG: nme:NMB1098 I protein; hypothetical protein 766726 6108475 HSM_0670 Haemophilus somnus 2336 hypothetical protein YP_001784008.1 765686 D 228400 CDS YP_001784009.1 170718831 6108477 766731..767657 1 NC_010519.1 KEGG: hdu:HD0519 bacteriophage mu T protein homolog; bacteriophage mu T-like protein 767657 6108477 HSM_0671 Haemophilus somnus 2336 bacteriophage mu T-like protein YP_001784009.1 766731 D 228400 CDS YP_001784010.1 170718832 6108478 767701..768171 1 NC_010519.1 KEGG: hdu:HD0520 hypothetical protein; hypothetical protein 768171 6108478 HSM_0672 Haemophilus somnus 2336 hypothetical protein YP_001784010.1 767701 D 228400 CDS YP_001784011.1 170718833 6108479 768174..768608 1 NC_010519.1 PFAM: protein of unknown function DUF1320; KEGG: nme:NMB1101 hypothetical protein; hypothetical protein 768608 6108479 HSM_0673 Haemophilus somnus 2336 hypothetical protein YP_001784011.1 768174 D 228400 CDS YP_001784012.1 170718834 6108480 768520..769233 1 NC_010519.1 PFAM: Domain of unknown function DUF1834; KEGG: nme:NMB1102 hypothetical protein; hypothetical protein 769233 6108480 HSM_0674 Haemophilus somnus 2336 hypothetical protein YP_001784012.1 768520 D 228400 CDS YP_001784013.1 170718835 6108481 769230..769412 1 NC_010519.1 KEGG: dvu:DVU2715 hypothetical protein; hypothetical protein 769412 6108481 HSM_0675 Haemophilus somnus 2336 hypothetical protein YP_001784013.1 769230 D 228400 CDS YP_001784014.1 170718836 6108482 769405..770820 1 NC_010519.1 PFAM: bacteriophage Mu tail sheath family protein; KEGG: nme:NMB1104 phage sheath protein; bacteriophage Mu tail sheath family protein 770820 6108482 HSM_0676 Haemophilus somnus 2336 bacteriophage Mu tail sheath family protein YP_001784014.1 769405 D 228400 CDS YP_001784015.1 170718837 6108483 770830..771204 1 NC_010519.1 KEGG: nme:NMB1105 hypothetical protein; hypothetical protein 771204 6108483 HSM_0677 Haemophilus somnus 2336 hypothetical protein YP_001784015.1 770830 D 228400 CDS YP_001784016.1 170718838 6108484 771204..771575 1 NC_010519.1 hypothetical protein 771575 6108484 HSM_0678 Haemophilus somnus 2336 hypothetical protein YP_001784016.1 771204 D 228400 CDS YP_001784017.1 170718839 6108485 771838..774255 1 NC_010519.1 KEGG: nme:NMB1108 hypothetical protein; hypothetical protein 774255 6108485 HSM_0679 Haemophilus somnus 2336 hypothetical protein YP_001784017.1 771838 D 228400 CDS YP_001784018.1 170718841 6108486 774258..775589 1 NC_010519.1 KEGG: nme:NMB1109 phage virion protein; phage virion protein 775589 6108486 HSM_0680 Haemophilus somnus 2336 phage virion protein YP_001784018.1 774258 D 228400 CDS YP_001784019.1 170718842 6108488 775579..776724 1 NC_010519.1 PFAM: bacteriophage Mu P family protein; KEGG: nma:NMA1320 hypothetical protein; bacteriophage Mu P family protein 776724 6108488 HSM_0681 Haemophilus somnus 2336 bacteriophage Mu P family protein YP_001784019.1 775579 D 228400 CDS YP_001784020.1 170718843 6108489 776724..777380 1 NC_010519.1 TIGRFAM: phage baseplate assembly protein V; PFAM: bacteriophage Mu Gp45 domain protein; KEGG: nma:NMA1321 hypothetical protein; phage baseplate assembly protein V 777380 6108489 HSM_0682 Haemophilus somnus 2336 phage baseplate assembly protein V YP_001784020.1 776724 D 228400 CDS YP_001784021.1 170718844 6108490 777459..777809 1 NC_010519.1 PFAM: phage GP46 family protein; KEGG: nma:NMA1322 hypothetical protein; phage GP46 family protein 777809 6108490 HSM_0683 Haemophilus somnus 2336 phage GP46 family protein YP_001784021.1 777459 D 228400 CDS YP_001784022.1 170718845 6108491 777823..778887 1 NC_010519.1 PFAM: Baseplate J family protein; KEGG: nma:NMA1323 hypothetical protein; baseplate J family protein 778887 6108491 HSM_0684 Haemophilus somnus 2336 baseplate J family protein YP_001784022.1 777823 D 228400 CDS YP_001784023.1 170718846 6108492 778887..779474 1 NC_010519.1 KEGG: nmc:NMC1057 hypothetical protein; hypothetical protein 779474 6108492 HSM_0685 Haemophilus somnus 2336 hypothetical protein YP_001784023.1 778887 D 228400 CDS YP_001784024.1 170718847 6108493 779478..781436 1 NC_010519.1 PFAM: phage tail fiber repeat 2 protein; phage Tail Collar domain protein; KEGG: hit:NTHI1857 probable tail fiber protein; phage tail collar domain-containing protein 781436 6108493 HSM_0686 Haemophilus somnus 2336 phage tail collar domain-containing protein YP_001784024.1 779478 D 228400 CDS YP_001784025.1 170718848 6108494 781433..782047 1 NC_010519.1 KEGG: hit:NTHI1553 hypothetical protein; hypothetical protein 782047 6108494 HSM_0687 Haemophilus somnus 2336 hypothetical protein YP_001784025.1 781433 D 228400 CDS YP_001784026.1 170718849 6108495 782040..782534 1 NC_010519.1 KEGG: hit:NTHI1554 hypothetical protein; hypothetical protein 782534 6108495 HSM_0688 Haemophilus somnus 2336 hypothetical protein YP_001784026.1 782040 D 228400 CDS YP_001784027.1 170718850 6108496 782902..783660 1 NC_010519.1 KEGG: mmy:MSC_0780 C5 methylase (MAV1virus-like); C5 methylase 783660 6108496 HSM_0689 Haemophilus somnus 2336 C5 methylase YP_001784027.1 782902 D 228400 CDS YP_001784028.1 170718852 6108497 783647..784483 1 NC_010519.1 KEGG: hdu:HD0156 hypothetical protein; hypothetical protein 784483 6108497 HSM_0690 Haemophilus somnus 2336 hypothetical protein YP_001784028.1 783647 D 228400 CDS YP_001784029.1 170718853 6108499 complement(784504..784692) 1 NC_010519.1 KEGG: mxa:MXAN_1831 hypothetical protein; hypothetical protein 784692 6108499 HSM_0691 Haemophilus somnus 2336 hypothetical protein YP_001784029.1 784504 R 228400 CDS YP_001784030.1 170718854 6108500 complement(784696..785010) 1 NC_010519.1 hypothetical protein 785010 6108500 HSM_0692 Haemophilus somnus 2336 hypothetical protein YP_001784030.1 784696 R 228400 CDS YP_001784031.1 170718855 6108501 complement(785160..786344) 1 NC_010519.1 PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: vch:VCA0977 ABC transporter ATP-binding protein; ABC transporter 786344 6108501 HSM_0693 Haemophilus somnus 2336 ABC transporter YP_001784031.1 785160 R 228400 CDS YP_001784032.1 170718856 6108502 complement(786356..787276) 1 NC_010519.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hit:NTHI1288 oligopeptide transporter permease protein; binding-protein-dependent transporters inner membrane component 787276 6108502 HSM_0694 Haemophilus somnus 2336 binding-protein-dependent transporters inner membrane component YP_001784032.1 786356 R 228400 CDS YP_001784033.1 170718857 6108503 complement(787286..788209) 1 NC_010519.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hin:HI1123 oligopeptide transporter permease protein; alkaline phosphatase 788209 6108503 HSM_0695 Haemophilus somnus 2336 alkaline phosphatase YP_001784033.1 787286 R 228400 CDS YP_001784034.1 170718858 6108504 complement(788322..789959) 1 NC_010519.1 PFAM: extracellular solute-binding protein family 5; KEGG: hit:NTHI1292 periplasmic oligopeptide-binding protein; extracellular solute-binding protein 789959 6108504 HSM_0696 Haemophilus somnus 2336 extracellular solute-binding protein YP_001784034.1 788322 R 228400 CDS YP_001784035.1 170718859 6108505 complement(790118..791773) 1 NC_010519.1 PFAM: extracellular solute-binding protein family 5; KEGG: hit:NTHI1292 periplasmic oligopeptide-binding protein; extracellular solute-binding protein 791773 6108505 HSM_0697 Haemophilus somnus 2336 extracellular solute-binding protein YP_001784035.1 790118 R 228400 CDS YP_001784036.1 170718860 6108506 792010..792672 1 NC_010519.1 PFAM: TrkA-N domain protein; KEGG: hso:HS_0375 K+ transporter; TrkA domain-containing protein 792672 6108506 HSM_0698 Haemophilus somnus 2336 TrkA domain-containing protein YP_001784036.1 792010 D 228400 CDS YP_001784037.1 170718861 6108507 792662..793981 1 NC_010519.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: hso:HS_0376 cation transporter; TrkH family potassium uptake protein 793981 6108507 HSM_0699 Haemophilus somnus 2336 TrkH family potassium uptake protein YP_001784037.1 792662 D 228400 CDS YP_001784038.1 170718864 6108508 complement(794099..796102) 1 NC_010519.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 796102 ligA 6108508 ligA Haemophilus somnus 2336 NAD-dependent DNA ligase LigA YP_001784038.1 794099 R 228400 CDS YP_001784039.1 170718865 6108511 complement(796229..797578) 1 NC_010519.1 TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter; KEGG: hso:HS_0378 gluconate permease; gluconate transporter 797578 6108511 HSM_0701 Haemophilus somnus 2336 gluconate transporter YP_001784039.1 796229 R 228400 CDS YP_001784040.1 170718866 6108512 complement(797600..798364) 1 NC_010519.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 798364 6108512 HSM_0702 Haemophilus somnus 2336 gluconate 5-dehydrogenase YP_001784040.1 797600 R 228400 CDS YP_001784041.1 170718867 6108513 complement(798375..799418) 1 NC_010519.1 NAD-binding; L-idonate 5-dehydrogenase 799418 6108513 HSM_0703 Haemophilus somnus 2336 L-idonate 5-dehydrogenase YP_001784041.1 798375 R 228400 CDS YP_001784042.1 170718868 6108514 799663..800181 1 NC_010519.1 TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase; KEGG: hso:HS_0379 gluconokinase (gluconate kinase); carbohydrate kinase 800181 6108514 HSM_0704 Haemophilus somnus 2336 carbohydrate kinase YP_001784042.1 799663 D 228400 CDS YP_001784043.1 170718869 6108515 800671..801699 1 NC_010519.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: hso:HS_0380 conserved hypothetical protein; TRAP transporter solute receptor TAXI family protein 801699 6108515 HSM_0705 Haemophilus somnus 2336 TRAP transporter solute receptor TAXI family protein YP_001784043.1 800671 D 228400 CDS YP_001784044.1 170718870 6108516 801721..802194 1 NC_010519.1 PFAM: Domain of unknown function DUF1850; KEGG: hso:HS_0381 hypothetical protein; hypothetical protein 802194 6108516 HSM_0706 Haemophilus somnus 2336 hypothetical protein YP_001784044.1 801721 D 228400 CDS YP_001784045.1 170718871 6108517 802187..804163 1 NC_010519.1 TIGRFAM: TRAP transporter 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_0382 conserved integral membrane protein; TRAP transporter 4TM/12TM fusion protein 804163 6108517 HSM_0707 Haemophilus somnus 2336 TRAP transporter 4TM/12TM fusion protein YP_001784045.1 802187 D 228400 CDS YP_001784046.1 170718872 6108518 complement(804395..815419) 1 NC_010519.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1085 large adhesin; YadA domain-containing protein 815419 6108518 HSM_0708 Haemophilus somnus 2336 YadA domain-containing protein YP_001784046.1 804395 R 228400 CDS YP_001784047.1 170718873 6108519 816087..817667 1 NC_010519.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 817667 prfC 6108519 prfC Haemophilus somnus 2336 peptide chain release factor 3 YP_001784047.1 816087 D 228400 CDS YP_001784048.1 170718875 6108520 complement(817784..820231) 1 NC_010519.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 820231 6108520 HSM_0710 Haemophilus somnus 2336 glycerol-3-phosphate acyltransferase YP_001784048.1 817784 R 228400 CDS YP_001784049.1 170718876 6108522 820381..821013 1 NC_010519.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 821013 6108522 HSM_0711 Haemophilus somnus 2336 LexA repressor YP_001784049.1 820381 D 228400 CDS YP_001784050.1 170718877 6108523 complement(821100..821525) 1 NC_010519.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 821525 ndk 6108523 ndk Haemophilus somnus 2336 nucleoside diphosphate kinase YP_001784050.1 821100 R 228400 CDS YP_001784051.1 170718878 6108524 complement(821537..822835) 1 NC_010519.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 822835 6108524 HSM_0713 Haemophilus somnus 2336 aminopeptidase B YP_001784051.1 821537 R 228400 CDS YP_001784052.1 170718879 6108525 complement(822945..823547) 1 NC_010519.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 823547 leuD 6108525 leuD Haemophilus somnus 2336 isopropylmalate isomerase small subunit YP_001784052.1 822945 R 228400 CDS YP_001784053.1 170718880 6108526 complement(823557..824966) 1 NC_010519.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 824966 6108526 HSM_0715 Haemophilus somnus 2336 isopropylmalate isomerase large subunit YP_001784053.1 823557 R 228400 CDS YP_001784054.1 170718881 6108527 complement(825066..826142) 1 NC_010519.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 826142 6108527 HSM_0716 Haemophilus somnus 2336 3-isopropylmalate dehydrogenase YP_001784054.1 825066 R 228400 CDS YP_001784055.1 170718882 6108528 complement(826166..827719) 1 NC_010519.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 827719 6108528 HSM_0717 Haemophilus somnus 2336 2-isopropylmalate synthase YP_001784055.1 826166 R 228400 CDS YP_001784056.1 170718883 6108529 828316..828969 1 NC_010519.1 ATP-binding protein; required for proper cytochrome C maturation; cytochrome C biogenesis protein CcmA 828969 6108529 HSM_0718 Haemophilus somnus 2336 cytochrome C biogenesis protein CcmA YP_001784056.1 828316 D 228400 CDS YP_001784057.1 170718884 6108530 828966..829631 1 NC_010519.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: hso:HS_0394 heme ABC transporter permease (heme exporter protein B); heme exporter protein CcmB 829631 6108530 HSM_0719 Haemophilus somnus 2336 heme exporter protein CcmB YP_001784057.1 828966 D 228400 CDS YP_001784058.1 170718886 6108531 829678..830412 1 NC_010519.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome C assembly protein; KEGG: hso:HS_0395 heme ABC transporter permease (heme exporter protein C); heme exporter protein CcmC 830412 6108531 HSM_0720 Haemophilus somnus 2336 heme exporter protein CcmC YP_001784058.1 829678 D 228400 CDS YP_001784059.1 170718887 6108533 830422..830634 1 NC_010519.1 PFAM: Heme exporter protein D (CcmD); KEGG: hso:HS_0396 heme ABC transporter substrate-binding protein (heme exporter protein D); Heme exporter protein CcmD 830634 6108533 HSM_0721 Haemophilus somnus 2336 Heme exporter protein CcmD YP_001784059.1 830422 D 228400 CDS YP_001784060.1 170718888 6108534 830631..831155 1 NC_010519.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome C maturation system; periplasmic protein anchored to the inner membrane; cytochrome C biogenesis protein CcmE 831155 6108534 HSM_0722 Haemophilus somnus 2336 cytochrome C biogenesis protein CcmE YP_001784060.1 830631 D 228400 CDS YP_001784061.1 170718889 6108535 831152..833101 1 NC_010519.1 TIGRFAM: cytochrome C biogenesis protein CcmF; PFAM: cytochrome C assembly protein; KEGG: hso:HS_0398 cytochrome C biogenesis protein F; cytochrome C biogenesis protein CcmF 833101 6108535 HSM_0723 Haemophilus somnus 2336 cytochrome C biogenesis protein CcmF YP_001784061.1 831152 D 228400 CDS YP_001784062.1 170718890 6108536 833105..833650 1 NC_010519.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: hso:HS_0399 thiol:disulfide interchange protein; periplasmic protein thiol--disulfide oxidoreductase DsbE 833650 6108536 HSM_0724 Haemophilus somnus 2336 periplasmic protein thiol--disulfide oxidoreductase DsbE YP_001784062.1 833105 D 228400 CDS YP_001784063.1 170718891 6108537 833647..834117 1 NC_010519.1 PFAM: cytochrome C biogenesis protein; KEGG: hso:HS_0400 cytochrome C biogenesis protein H; cytochrome C biogenesis protein 834117 6108537 HSM_0725 Haemophilus somnus 2336 cytochrome C biogenesis protein YP_001784063.1 833647 D 228400 CDS YP_001784064.1 170718892 6108538 834121..835005 1 NC_010519.1 KEGG: hso:HS_0401 cytochrome C biogenesis protein, with TPR repeats; TPR repeat-containing cytochrome C biogenesis protein 835005 6108538 HSM_0726 Haemophilus somnus 2336 TPR repeat-containing cytochrome C biogenesis protein YP_001784064.1 834121 D 228400 CDS YP_001784065.1 170718893 6108539 835018..836874 1 NC_010519.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: hso:HS_0402 sensor histidine kinase; multi-sensor hybrid histidine kinase 836874 6108539 HSM_0727 Haemophilus somnus 2336 multi-sensor hybrid histidine kinase YP_001784065.1 835018 D 228400 CDS YP_001784066.1 170718894 6108540 836961..837917 1 NC_010519.1 KEGG: hso:HS_0403 hypothetical protein; hypothetical protein 837917 6108540 HSM_0728 Haemophilus somnus 2336 hypothetical protein YP_001784066.1 836961 D 228400 CDS YP_001784067.1 170718895 6108541 837924..839030 1 NC_010519.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 839030 ispG 6108541 ispG Haemophilus somnus 2336 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_001784067.1 837924 D 228400 CDS YP_001784068.1 170718897 6108542 839043..840320 1 NC_010519.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 840320 hisS 6108542 hisS Haemophilus somnus 2336 histidyl-tRNA synthetase YP_001784068.1 839043 D 228400 CDS YP_001784069.1 170718898 6108544 840331..840942 1 NC_010519.1 KEGG: hso:HS_0406 hypothetical protein; hypothetical protein 840942 6108544 HSM_0731 Haemophilus somnus 2336 hypothetical protein YP_001784069.1 840331 D 228400 CDS YP_001784070.1 170718899 6108545 841000..842445 1 NC_010519.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: hso:HS_0407 succinate-semialdehyde dehydrogenase (NAD(P)+); succinate-semialdehyde dehydrogenase 842445 6108545 HSM_0732 Haemophilus somnus 2336 succinate-semialdehyde dehydrogenase YP_001784070.1 841000 D 228400 CDS YP_001784071.1 170718900 6108546 complement(842601..843857) 1 NC_010519.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 843857 proA 6108546 proA Haemophilus somnus 2336 gamma-glutamyl phosphate reductase YP_001784071.1 842601 R 228400 CDS YP_001784072.1 170718901 6108547 complement(843867..844538) 1 NC_010519.1 PFAM: protein of unknown function UPF0126; KEGG: hso:HS_0409 hypothetical protein; hypothetical protein 844538 6108547 HSM_0734 Haemophilus somnus 2336 hypothetical protein YP_001784072.1 843867 R 228400 CDS YP_001784073.1 170718902 6108548 complement(844699..845286) 1 NC_010519.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 845286 6108548 HSM_0735 Haemophilus somnus 2336 thymidine kinase YP_001784073.1 844699 R 228400 CDS YP_001784074.1 170718903 6108549 complement(845348..846376) 1 NC_010519.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 846376 6108549 HSM_0736 Haemophilus somnus 2336 DNA-binding/iron metalloprotein/AP endonuclease YP_001784074.1 845348 R 228400 CDS YP_001784075.1 170718904 6108550 846611..847717 1 NC_010519.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: hso:HS_0412 DNA processing chain A; DNA protecting protein DprA 847717 6108550 HSM_0737 Haemophilus somnus 2336 DNA protecting protein DprA YP_001784075.1 846611 D 228400 CDS YP_001784076.1 170718905 6108551 complement(847700..848302) 1 NC_010519.1 TIGRFAM: methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: hso:HS_0413 conserved methylase; methyltransferase 848302 6108551 HSM_0738 Haemophilus somnus 2336 methyltransferase YP_001784076.1 847700 R 228400 CDS YP_001784077.1 170718906 6108552 848366..849709 1 NC_010519.1 TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase; KEGG: hso:HS_0414 cell division protein; signal recognition particle-docking protein FtsY 849709 6108552 HSM_0739 Haemophilus somnus 2336 signal recognition particle-docking protein FtsY YP_001784077.1 848366 D 228400 CDS YP_001784078.1 170718908 6108553 complement(849871..851442) 1 NC_010519.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: hso:HS_0415 conserved membrane protein; integral membrane protein MviN 851442 6108553 HSM_0740 Haemophilus somnus 2336 integral membrane protein MviN YP_001784078.1 849871 R 228400 CDS YP_001784079.1 170718909 6108555 851720..851983 1 NC_010519.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 851983 rpsT 6108555 rpsT Haemophilus somnus 2336 30S ribosomal protein S20 YP_001784079.1 851720 D 228400 CDS YP_001784080.1 170718910 6108556 complement(852045..853895) 1 NC_010519.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: hso:HS_0417 GTP-binding protein; GTP-binding protein TypA 853895 6108556 HSM_0742 Haemophilus somnus 2336 GTP-binding protein TypA YP_001784080.1 852045 R 228400 CDS YP_001784081.1 170718911 6108557 854138..855556 1 NC_010519.1 TIGRFAM: glutamine synthetase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: hso:HS_0418 glutamate--ammonia ligase (glutamine synthetase); glutamine synthetase 855556 6108557 HSM_0743 Haemophilus somnus 2336 glutamine synthetase YP_001784081.1 854138 D 228400 CDS YP_001784082.1 170718912 6108558 complement(855781..856713) 1 NC_010519.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 856713 6108558 HSM_0744 Haemophilus somnus 2336 biotin--protein ligase YP_001784082.1 855781 R 228400 CDS YP_001784083.1 170718913 6108559 856882..858345 1 NC_010519.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 858345 6108559 HSM_0745 Haemophilus somnus 2336 inosine 5'-monophosphate dehydrogenase YP_001784083.1 856882 D 228400 CDS YP_001784084.1 170718914 6108560 858746..860317 1 NC_010519.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 860317 guaA 6108560 guaA Haemophilus somnus 2336 GMP synthase YP_001784084.1 858746 D 228400 CDS YP_001784085.1 170718915 6108561 complement(860564..860824) 1 NC_010519.1 KEGG: hso:HS_1709 transposase; transposase 860824 6108561 HSM_0747 Haemophilus somnus 2336 transposase YP_001784085.1 860564 R 228400 CDS YP_001784086.1 170718916 6108562 861565..862353 1 NC_010519.1 PFAM: glycoside hydrolase family 29 (alpha-L-fucosidase); KEGG: hso:HS_0435 alpha-L-fucosidase; alpha-L-fucosidase 862353 6108562 HSM_0748 Haemophilus somnus 2336 alpha-L-fucosidase YP_001784086.1 861565 D 228400 CDS YP_001784087.1 170718917 6108563 862512..864500 1 NC_010519.1 PFAM: transferrin binding protein; KEGG: hso:HS_0448 transferrin-binding protein; transferrin binding protein 864500 6108563 HSM_0749 Haemophilus somnus 2336 transferrin binding protein YP_001784087.1 862512 D 228400 CDS YP_001784088.1 170718919 6108564 864686..867601 1 NC_010519.1 TIGRFAM: TonB-dependent lactoferrin and transferrin receptors; TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0449 transferrin-binding protein A; TonB-dependent lactoferrin and transferrin receptor 867601 6108564 HSM_0750 Haemophilus somnus 2336 TonB-dependent lactoferrin and transferrin receptor YP_001784088.1 864686 D 228400 CDS YP_001784089.1 170718920 6108566 867911..869791 1 NC_010519.1 molecular chaperone; heat shock protein 90 869791 6108566 HSM_0751 Haemophilus somnus 2336 heat shock protein 90 YP_001784089.1 867911 D 228400 CDS YP_001784090.1 170718921 6108567 869979..870227 1 NC_010519.1 KEGG: hso:HS_0454 hypothetical protein; hypothetical protein 870227 6108567 HSM_0752 Haemophilus somnus 2336 hypothetical protein YP_001784090.1 869979 D 228400 CDS YP_001784091.1 170718922 6108568 870266..871000 1 NC_010519.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: hso:HS_0455 4'-phosphopantetheinyl transferase family protein; 4'-phosphopantetheinyl transferase 871000 6108568 HSM_0753 Haemophilus somnus 2336 4'-phosphopantetheinyl transferase YP_001784091.1 870266 D 228400 CDS YP_001784092.1 170718923 6108868 complement(871339..872781) 1 NC_010519.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 872781 gltX 6108868 gltX Haemophilus somnus 2336 glutamyl-tRNA synthetase YP_001784092.1 871339 R 228400 CDS YP_001784093.1 170718924 6108871 873478..874698 1 NC_010519.1 PFAM: type II secretion system protein; KEGG: hso:HS_0457 protein transporter; type II secretion system protein 874698 6108871 HSM_0755 Haemophilus somnus 2336 type II secretion system protein YP_001784093.1 873478 D 228400 CDS YP_001784094.1 170718925 6108571 874695..875402 1 NC_010519.1 PFAM: peptidase A24A prepilin type IV; KEGG: hso:HS_0458 prepilin peptidase; peptidase A24A prepilin type IV 875402 6108571 HSM_0756 Haemophilus somnus 2336 peptidase A24A prepilin type IV YP_001784094.1 874695 D 228400 CDS YP_001784095.1 170718926 6108572 875422..876069 1 NC_010519.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 876069 coaE 6108572 coaE Haemophilus somnus 2336 dephospho-CoA kinase YP_001784095.1 875422 D 228400 CDS YP_001784096.1 170718927 6108573 876066..876260 1 NC_010519.1 PFAM: protein of unknown function DUF329; KEGG: hso:HS_0460 hypothetical protein; hypothetical protein 876260 6108573 HSM_0758 Haemophilus somnus 2336 hypothetical protein YP_001784096.1 876066 D 228400 CDS YP_001784097.1 170718928 6108574 876433..876636 1 NC_010519.1 KEGG: hso:HS_0460a hypothetical protein; hypothetical protein 876636 6108574 HSM_0759 Haemophilus somnus 2336 hypothetical protein YP_001784097.1 876433 D 228400 CDS YP_001784098.1 170718930 6108575 876664..878040 1 NC_010519.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: hso:HS_0461 D-alanine glycine permease; amino acid carrier protein 878040 6108575 HSM_0760 Haemophilus somnus 2336 amino acid carrier protein YP_001784098.1 876664 D 228400 CDS YP_001784099.1 170718931 6108577 878276..878593 1 NC_010519.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: hso:HS_0462 ribosome-associated protein Y; sigma 54 modulation protein/30S ribosomal protein S30EA 878593 6108577 HSM_0761 Haemophilus somnus 2336 sigma 54 modulation protein/30S ribosomal protein S30EA YP_001784099.1 878276 D 228400 CDS YP_001784100.1 170718932 6108578 878797..879336 1 NC_010519.1 TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: hso:HS_0463 hypoxanthine phosphoribosyltransferase (HPRT); hypoxanthine phosphoribosyltransferase 879336 6108578 HSM_0762 Haemophilus somnus 2336 hypoxanthine phosphoribosyltransferase YP_001784100.1 878797 D 228400 CDS YP_001784101.1 170718933 6108579 complement(879464..880093) 1 NC_010519.1 PFAM: manganese and iron superoxide dismutase; KEGG: hso:HS_0464 superoxide dismutase, manganese; superoxide dismutase 880093 6108579 HSM_0763 Haemophilus somnus 2336 superoxide dismutase YP_001784101.1 879464 R 228400 CDS YP_001784102.1 170718934 6108580 complement(880230..882497) 1 NC_010519.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 882497 6108580 HSM_0764 Haemophilus somnus 2336 malic enzyme YP_001784102.1 880230 R 228400 CDS YP_001784103.1 170718935 6108581 complement(882692..884107) 1 NC_010519.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 884107 aspA 6108581 aspA Haemophilus somnus 2336 aspartate ammonia-lyase YP_001784103.1 882692 R 228400 CDS YP_001784104.1 170718936 6108582 884345..884635 1 NC_010519.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 884635 groES 6108582 groES Haemophilus somnus 2336 co-chaperonin GroES YP_001784104.1 884345 D 228400 CDS YP_001784105.1 170718937 6108583 884666..886309 1 NC_010519.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 886309 groEL 6108583 groEL Haemophilus somnus 2336 chaperonin GroEL YP_001784105.1 884666 D 228400 CDS YP_001784106.1 170718938 6108584 886480..886797 1 NC_010519.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 886797 6108584 HSM_0768 Haemophilus somnus 2336 transcriptional repressor protein MetJ YP_001784106.1 886480 D 228400 CDS YP_001784107.1 170718939 6108585 886881..887483 1 NC_010519.1 KEGG: hso:HS_0470 hypothetical protein; hypothetical protein 887483 6108585 HSM_0769 Haemophilus somnus 2336 hypothetical protein YP_001784107.1 886881 D 228400 CDS YP_001784108.1 170718941 6108586 887487..887930 1 NC_010519.1 KEGG: hso:HS_0471 hypothetical protein; hypothetical protein 887930 6108586 HSM_0770 Haemophilus somnus 2336 hypothetical protein YP_001784108.1 887487 D 228400 CDS YP_001784109.1 170718942 6108588 887931..889298 1 NC_010519.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 889298 6108588 HSM_0771 Haemophilus somnus 2336 coproporphyrinogen III oxidase YP_001784109.1 887931 D 228400 CDS YP_001784110.1 170718943 6108589 complement(889332..889814) 1 NC_010519.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 889814 smpB 6108589 smpB Haemophilus somnus 2336 SsrA-binding protein YP_001784110.1 889332 R 228400 CDS YP_001784111.1 170718944 6108590 889942..891417 1 NC_010519.1 TIGRFAM: UbiD family decarboxylase; PFAM: carboxylyase-related protein; KEGG: hso:HS_0474 3-octaprenyl-4-hydroxybenzoate carboxy-lyase (polyprenyl p-hydroxybenzoate decarboxylase); UbiD family decarboxylase 891417 6108590 HSM_0773 Haemophilus somnus 2336 UbiD family decarboxylase YP_001784111.1 889942 D 228400 CDS YP_001784112.1 170718945 6108591 complement(891457..892659) 1 NC_010519.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 892659 6108591 HSM_0774 Haemophilus somnus 2336 cystathionine beta-lyase YP_001784112.1 891457 R 228400 CDS YP_001784113.1 170718946 6108592 892800..893402 1 NC_010519.1 PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: hso:HS_0476 AhpC/TSA family protein; alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen 893402 6108592 HSM_0775 Haemophilus somnus 2336 alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen YP_001784113.1 892800 D 228400 CDS YP_001784114.1 170718947 6108593 complement(893587..893856) 1 NC_010519.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 893856 rpsO 6108593 rpsO Haemophilus somnus 2336 30S ribosomal protein S15 YP_001784114.1 893587 R 228400 CDS YP_001784115.1 170718948 6108594 894222..895697 1 NC_010519.1 PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_1282 permease, major facilitator superfamily; major facilitator transporter 895697 6108594 HSM_0777 Haemophilus somnus 2336 major facilitator transporter YP_001784115.1 894222 D 228400 CDS YP_001784116.1 170718949 6108595 896006..896815 1 NC_010519.1 KEGG: hso:HS_1281 permease; permease 896815 6108595 HSM_0778 Haemophilus somnus 2336 permease YP_001784116.1 896006 D 228400 CDS YP_001784117.1 170718950 6108596 complement(896934..897281) 1 NC_010519.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 897281 6108596 HSM_0779 Haemophilus somnus 2336 fumarate reductase subunit D YP_001784117.1 896934 R 228400 CDS YP_001784118.1 170718952 6108597 complement(897292..897696) 1 NC_010519.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 897696 6108597 HSM_0780 Haemophilus somnus 2336 fumarate reductase subunit C YP_001784118.1 897292 R 228400 CDS YP_001784119.1 170718953 6108599 complement(897707..898477) 1 NC_010519.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 898477 6108599 HSM_0781 Haemophilus somnus 2336 fumarate reductase iron-sulfur subunit YP_001784119.1 897707 R 228400 CDS YP_001784120.1 170718954 6108600 complement(898470..900269) 1 NC_010519.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 900269 6108600 HSM_0782 Haemophilus somnus 2336 fumarate reductase flavoprotein subunit YP_001784120.1 898470 R 228400 CDS YP_001784121.1 170718955 6108601 900582..901553 1 NC_010519.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 901553 6108601 HSM_0783 Haemophilus somnus 2336 lysyl-tRNA synthetase YP_001784121.1 900582 D 228400 CDS YP_001784122.1 170718956 6108602 complement(901607..903193) 1 NC_010519.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: hso:HS_1275 FAD flavoprotein oxidase; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein 903193 6108602 HSM_0784 Haemophilus somnus 2336 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein YP_001784122.1 901607 R 228400 CDS YP_001784123.1 170718957 6108603 complement(903274..904080) 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1274 ABC transporter ATP-binding protein; ABC transporter 904080 6108603 HSM_0785 Haemophilus somnus 2336 ABC transporter YP_001784123.1 903274 R 228400 CDS YP_001784124.1 170718958 6108604 complement(904084..906036) 1 NC_010519.1 PFAM: binding-protein-dependent transporters inner membrane component; ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: hso:HS_1273 ABC transporter permease/ATP-binding protein; ABC transporter 906036 6108604 HSM_0786 Haemophilus somnus 2336 ABC transporter YP_001784124.1 904084 R 228400 CDS YP_001784125.1 170718959 6108605 complement(906036..906989) 1 NC_010519.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_1272 ABC transporter permease; binding-protein-dependent transporters inner membrane component 906989 6108605 HSM_0787 Haemophilus somnus 2336 binding-protein-dependent transporters inner membrane component YP_001784125.1 906036 R 228400 CDS YP_001784126.1 170718960 6108606 complement(907127..908713) 1 NC_010519.1 PFAM: extracellular solute-binding protein family 5; KEGG: hso:HS_1271 ABC transporter periplasmic binding protein; extracellular solute-binding protein 908713 6108606 HSM_0788 Haemophilus somnus 2336 extracellular solute-binding protein YP_001784126.1 907127 R 228400 CDS YP_001784127.1 170718961 6108607 complement(909036..911534) 1 NC_010519.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 911534 6108607 HSM_0789 Haemophilus somnus 2336 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_001784127.1 909036 R 228400 CDS YP_001784128.1 170718963 6108608 complement(911817..912116) 1 NC_010519.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 912116 6108608 HSM_0790 Haemophilus somnus 2336 YciI-like protein YP_001784128.1 911817 R 228400 CDS YP_001784129.1 170718964 6108610 complement(912136..912600) 1 NC_010519.1 PFAM: thioesterase superfamily protein; KEGG: hso:HS_1268 acyl-CoA hydrolase; thioesterase superfamily protein 912600 6108610 HSM_0791 Haemophilus somnus 2336 thioesterase superfamily protein YP_001784129.1 912136 R 228400 CDS YP_001784130.1 170718965 6108611 complement(912610..913149) 1 NC_010519.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 913149 6108611 HSM_0792 Haemophilus somnus 2336 intracellular septation protein A YP_001784130.1 912610 R 228400 CDS YP_001784131.1 170718966 6108612 complement(913149..913889) 1 NC_010519.1 KEGG: hso:HS_1266 membrane protein; hypothetical protein 913889 6108612 HSM_0793 Haemophilus somnus 2336 hypothetical protein YP_001784131.1 913149 R 228400 CDS YP_001784132.1 170718967 6108614 914974..915417 1 NC_010519.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 915417 6108614 HSM_0796 Haemophilus somnus 2336 DNA polymerase III subunit chi YP_001784132.1 914974 D 228400 CDS YP_001784133.1 170718968 6108615 915439..915894 1 NC_010519.1 KEGG: hso:HS_1263 Haemophilus-specific protein, uncharacterized; hypothetical protein 915894 6108615 HSM_0797 Haemophilus somnus 2336 hypothetical protein YP_001784133.1 915439 D 228400 CDS YP_001784134.1 170718969 6108616 915983..916807 1 NC_010519.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: hso:HS_1262 hypothetical protein; filamentation induced by cAMP protein fic 916807 6108616 HSM_0798 Haemophilus somnus 2336 filamentation induced by cAMP protein fic YP_001784134.1 915983 D 228400 CDS YP_001784135.1 170718970 6108617 916809..917003 1 NC_010519.1 KEGG: hso:HS_1261 hypothetical protein; hypothetical protein 917003 6108617 HSM_0799 Haemophilus somnus 2336 hypothetical protein YP_001784135.1 916809 D 228400 CDS YP_001784136.1 170718973 6108618 917206..917652 1 NC_010519.1 KEGG: hso:HS_1374 Haemophilus-specific protein, uncharacterized; hypothetical protein 917652 6108618 HSM_0800 Haemophilus somnus 2336 hypothetical protein YP_001784136.1 917206 D 228400 CDS YP_001784137.1 170718974 6108621 917815..918786 1 NC_010519.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: hpy:HP1121 cytosine specific DNA methyltransferase; DNA-cytosine methyltransferase 918786 6108621 HSM_0801 Haemophilus somnus 2336 DNA-cytosine methyltransferase YP_001784137.1 917815 D 228400 CDS YP_001784138.1 170718975 6108622 918797..919540 1 NC_010519.1 KEGG: hpj:jhp1049 hypothetical protein; hypothetical protein 919540 6108622 HSM_0802 Haemophilus somnus 2336 hypothetical protein YP_001784138.1 918797 D 228400 CDS YP_001784139.1 170718976 6108623 919587..922451 1 NC_010519.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 922451 valS 6108623 valS Haemophilus somnus 2336 valyl-tRNA synthetase YP_001784139.1 919587 D 228400 CDS YP_001784140.1 170718977 6108624 complement(922507..923316) 1 NC_010519.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 923316 truA 6108624 truA Haemophilus somnus 2336 tRNA pseudouridine synthase A YP_001784140.1 922507 R 228400 CDS YP_001784141.1 170718978 6108625 complement(923347..924258) 1 NC_010519.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 924258 6108625 HSM_0805 Haemophilus somnus 2336 cytidine deaminase YP_001784141.1 923347 R 228400 CDS YP_001784142.1 170718979 6108626 complement(924369..925268) 1 NC_010519.1 KEGG: hit:NTHI0936 HTH-type transcriptional regulator; HTH-type transcriptional regulator 925268 6108626 HSM_0806 Haemophilus somnus 2336 HTH-type transcriptional regulator YP_001784142.1 924369 R 228400 CDS YP_001784143.1 170718980 6108627 925565..926212 1 NC_010519.1 TIGRFAM: 3-oxoacid CoA-transferase, subunit alpha; KEGG: hit:NTHI0935 acetate CoA-transferase subunit alpha; 3-oxoacid CoA-transferase subunit A 926212 6108627 HSM_0807 Haemophilus somnus 2336 3-oxoacid CoA-transferase subunit A YP_001784143.1 925565 D 228400 CDS YP_001784144.1 170718981 6108628 926230..926889 1 NC_010519.1 TIGRFAM: 3-oxoacid CoA-transferase subunit beta; KEGG: hit:NTHI0934 acetate CoA-transferase subunit beta; 3-oxoacid CoA-transferase subunit B 926889 6108628 HSM_0808 Haemophilus somnus 2336 3-oxoacid CoA-transferase subunit B YP_001784144.1 926230 D 228400 CDS YP_001784145.1 170718982 6108629 926900..928243 1 NC_010519.1 KEGG: hin:HI0772 short-chain fatty acids transporter; short-chain fatty acids transporter 928243 6108629 HSM_0809 Haemophilus somnus 2336 short-chain fatty acids transporter YP_001784145.1 926900 D 228400 CDS YP_001784146.1 170718984 6108630 928335..929516 1 NC_010519.1 TIGRFAM: acetyl-CoA acetyltransferase; KEGG: ecp:ECP_2268 acetyl-CoA acetyltransferase; acetyl-CoA acetyltransferase 929516 6108630 HSM_0810 Haemophilus somnus 2336 acetyl-CoA acetyltransferase YP_001784146.1 928335 D 228400 CDS YP_001784147.1 170718985 6108632 929544..930302 1 NC_010519.1 TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: csa:Csal_1825 3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase 930302 6108632 HSM_0811 Haemophilus somnus 2336 3-hydroxybutyrate dehydrogenase YP_001784147.1 929544 D 228400 CDS YP_001784148.1 170718986 6108633 930373..931758 1 NC_010519.1 PFAM: gluconate transporter; citrate transporter; KEGG: pcr:Pcryo_1595 GntP family transporter; citrate transporter 931758 6108633 HSM_0812 Haemophilus somnus 2336 citrate transporter YP_001784148.1 930373 D 228400 CDS YP_001784149.1 170718987 6108634 complement(931926..933092) 1 NC_010519.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 933092 znuA 6108634 znuA Haemophilus somnus 2336 high-affinity zinc transporter periplasmic protein YP_001784149.1 931926 R 228400 CDS YP_001784150.1 170718988 6108635 complement(933185..933952) 1 NC_010519.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: hso:HS_1255 hypothetical protein; UBA/THIF-type NAD/FAD binding protein 933952 6108635 HSM_0814 Haemophilus somnus 2336 UBA/THIF-type NAD/FAD binding protein YP_001784150.1 933185 R 228400 CDS YP_001784151.1 170718989 6108636 complement(933952..935043) 1 NC_010519.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 935043 mltA 6108636 mltA Haemophilus somnus 2336 murein transglycosylase A YP_001784151.1 933952 R 228400 CDS YP_001784152.1 170718990 6108637 complement(935316..936224) 1 NC_010519.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 936224 6108637 HSM_0816 Haemophilus somnus 2336 fructokinase YP_001784152.1 935316 R 228400 CDS YP_001784153.1 170718991 6108638 936328..937056 1 NC_010519.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pmu:PM1376 hypothetical Rhizobium sp.; transcriptional regulator 937056 6108638 HSM_0817 Haemophilus somnus 2336 transcriptional regulator YP_001784153.1 936328 D 228400 CDS YP_001784154.1 170718992 6108639 complement(937089..938084) 1 NC_010519.1 PFAM: PfkB domain protein; KEGG: pmu:PM1372 sugar kinase; ribokinase 938084 6108639 HSM_0818 Haemophilus somnus 2336 ribokinase YP_001784154.1 937089 R 228400 CDS YP_001784155.1 170718993 6108640 complement(938071..938955) 1 NC_010519.1 TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; KEGG: pmu:PM1373 fructose-bisphosphate aldolase; hypothetical protein 938955 6108640 HSM_0819 Haemophilus somnus 2336 hypothetical protein YP_001784155.1 938071 R 228400 CDS YP_001784156.1 170718995 6108641 complement(938946..939626) 1 NC_010519.1 PFAM: protein of unknown function DUF1498; KEGG: pmu:PM1374 unknown; hypothetical protein 939626 6108641 HSM_0820 Haemophilus somnus 2336 hypothetical protein YP_001784156.1 938946 R 228400 CDS YP_001784157.1 170718996 6108643 complement(939733..940662) 1 NC_010519.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: pmu:PM1377 D-ribose binding periplasmic protein precursor; periplasmic binding protein/LacI transcriptional regulator 940662 6108643 HSM_0821 Haemophilus somnus 2336 periplasmic binding protein/LacI transcriptional regulator YP_001784157.1 939733 R 228400 CDS YP_001784158.1 170718997 6108644 complement(940717..941685) 1 NC_010519.1 PFAM: inner-membrane translocator; KEGG: pmu:PM1378 ribose ABC transporter permease; monosaccharide-transporting ATPase 941685 6108644 HSM_0822 Haemophilus somnus 2336 monosaccharide-transporting ATPase YP_001784158.1 940717 R 228400 CDS YP_001784159.1 170718998 6108645 complement(941708..943216) 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pmu:PM1379 ribose ABC transporter ATP-binding protein; ABC transporter 943216 6108645 HSM_0823 Haemophilus somnus 2336 ABC transporter YP_001784159.1 941708 R 228400 CDS YP_001784160.1 170718999 6108646 943549..945978 1 NC_010519.1 SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: pmu:PM1380 hybrid histidine protein kinase-phosphate acceptor regulatory protein; integral membrane sensor hybrid histidine kinase 945978 6108646 HSM_0824 Haemophilus somnus 2336 integral membrane sensor hybrid histidine kinase YP_001784160.1 943549 D 228400 CDS YP_001784161.1 170719000 6108647 946353..948230 1 NC_010519.1 TIGRFAM: PTS system, mannitol-specific IIC subunit; KEGG: hso:HS_1252 mannitol-specific IIABC component, PTS system; PTS system mannitol-specific transporter subunit IIC 948230 6108647 HSM_0825 Haemophilus somnus 2336 PTS system mannitol-specific transporter subunit IIC YP_001784161.1 946353 D 228400 CDS YP_001784162.1 170719001 6108648 948303..949460 1 NC_010519.1 KEGG: hso:HS_1251 mannitol 1-phosphate 5-dehydrogenase; mannitol-1-phosphate 5-dehydrogenase 949460 6108648 HSM_0826 Haemophilus somnus 2336 mannitol-1-phosphate 5-dehydrogenase YP_001784162.1 948303 D 228400 CDS YP_001784163.1 170719002 6108649 949535..950050 1 NC_010519.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 950050 mtlR 6108649 mtlR Haemophilus somnus 2336 mannitol repressor protein YP_001784163.1 949535 D 228400 CDS YP_001784164.1 170719003 6108650 complement(950147..951523) 1 NC_010519.1 TIGRFAM: UDP-N-acetylmuramate; KEGG: hso:HS_1249 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamayl-medo- diaminopimelate; UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 951523 6108650 HSM_0828 Haemophilus somnus 2336 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_001784164.1 950147 R 228400 CDS YP_001784165.1 170719004 6108651 951664..952671 1 NC_010519.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 952671 6108651 HSM_0829 Haemophilus somnus 2336 fructose-1,6-bisphosphatase YP_001784165.1 951664 D 228400 CDS YP_001784166.1 170719006 6108654 956232..956936 1 NC_010519.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 956936 6108654 HSM_0832 Haemophilus somnus 2336 peptidase E YP_001784166.1 956232 D 228400 CDS YP_001784167.1 170719007 6108655 956947..958239 1 NC_010519.1 TIGRFAM: anaerobic c4-dicarboxylate antiporter, DcuC family; PFAM: C4-dicarboxylate anaerobic carrier; citrate transporter; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_1244 permease, C4-dicarboxylate transporter; anaerobic c4-dicarboxylate antiporter 958239 6108655 HSM_0833 Haemophilus somnus 2336 anaerobic c4-dicarboxylate antiporter YP_001784167.1 956947 D 228400 CDS YP_001784168.1 170719008 6108657 959761..961557 1 NC_010519.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 961557 6108657 HSM_0836 Haemophilus somnus 2336 GTP-binding protein LepA YP_001784168.1 959761 D 228400 CDS YP_001784169.1 170719009 6108658 961568..962599 1 NC_010519.1 TIGRFAM: signal peptidase I; PFAM: peptidase S24 S26A and S26B; KEGG: hso:HS_1241 signal peptidase I; signal peptidase I 962599 6108658 HSM_0837 Haemophilus somnus 2336 signal peptidase I YP_001784169.1 961568 D 228400 CDS YP_001784170.1 170719010 6108659 962805..963476 1 NC_010519.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 963476 rnc 6108659 rnc Haemophilus somnus 2336 ribonuclease III YP_001784170.1 962805 D 228400 CDS YP_001784171.1 170719011 6108660 963517..964431 1 NC_010519.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 964431 era 6108660 era Haemophilus somnus 2336 GTP-binding protein Era YP_001784171.1 963517 D 228400 CDS YP_001784172.1 170719013 6108661 964456..965043 1 NC_010519.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 965043 gmhA 6108661 gmhA Haemophilus somnus 2336 phosphoheptose isomerase YP_001784172.1 964456 D 228400 CDS YP_001784173.1 170719014 6108663 965228..965443 1 NC_010519.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 965443 rpsU 6108663 rpsU Haemophilus somnus 2336 30S ribosomal protein S21 YP_001784173.1 965228 D 228400 CDS YP_001784174.1 170719015 6108664 965604..967361 1 NC_010519.1 synthesizes RNA primers at the replication forks; DNA primase 967361 dnaG 6108664 dnaG Haemophilus somnus 2336 DNA primase YP_001784174.1 965604 D 228400 CDS YP_001784175.1 170719016 6108665 967428..969293 1 NC_010519.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 969293 6108665 HSM_0843 Haemophilus somnus 2336 RNA polymerase sigma factor RpoD YP_001784175.1 967428 D 228400 CDS YP_001784176.1 170719017 6108666 969941..979357 1 NC_010519.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1616 large adhesin; YadA domain-containing protein 979357 6108666 HSM_0844 Haemophilus somnus 2336 YadA domain-containing protein YP_001784176.1 969941 D 228400 CDS YP_001784177.1 170719018 6108667 979743..980369 1 NC_010519.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: hso:HS_1233 membrane protein; hypothetical protein 980369 6108667 HSM_0845 Haemophilus somnus 2336 hypothetical protein YP_001784177.1 979743 D 228400 CDS YP_001784178.1 170719019 6108668 980482..981393 1 NC_010519.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 981393 glyQ 6108668 glyQ Haemophilus somnus 2336 glycyl-tRNA synthetase subunit alpha YP_001784178.1 980482 D 228400 CDS YP_001784179.1 170719020 6108669 981393..981662 1 NC_010519.1 KEGG: hso:HS_1231 hypothetical protein; hypothetical protein 981662 6108669 HSM_0847 Haemophilus somnus 2336 hypothetical protein YP_001784179.1 981393 D 228400 CDS YP_001784180.1 170719021 6108670 982522..982908 1 NC_010519.1 hypothetical protein 982908 6108670 HSM_0848 Haemophilus somnus 2336 hypothetical protein YP_001784180.1 982522 D 228400 CDS YP_001784181.1 170719022 6108671 983108..983362 1 NC_010519.1 KEGG: hso:HS_1230 hypothetical protein; hypothetical protein 983362 6108671 HSM_0849 Haemophilus somnus 2336 hypothetical protein YP_001784181.1 983108 D 228400 CDS YP_001784182.1 170719024 6108672 complement(983526..984824) 1 NC_010519.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 984824 6108672 HSM_0850 Haemophilus somnus 2336 glutamate-1-semialdehyde aminotransferase YP_001784182.1 983526 R 228400 CDS YP_001784183.1 170719025 6108879 complement(991488..992141) 1 NC_010519.1 KEGG: hso:HS_1709 transposase; transposase 992141 6108879 HSM_0851 Haemophilus somnus 2336 transposase YP_001784183.1 991488 R 228400 CDS YP_001784184.1 170719026 6108675 992748..993020 1 NC_010519.1 KEGG: hso:HS_1228 integrase; hypothetical protein 993020 6108675 HSM_0852 Haemophilus somnus 2336 hypothetical protein YP_001784184.1 992748 D 228400 CDS YP_001784185.1 170719027 6108676 993239..994234 1 NC_010519.1 KEGG: hso:HS_1227 hypothetical protein; hypothetical protein 994234 6108676 HSM_0853 Haemophilus somnus 2336 hypothetical protein YP_001784185.1 993239 D 228400 CDS YP_001784186.1 170719028 6108677 994314..995345 1 NC_010519.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 995345 6108677 HSM_0854 Haemophilus somnus 2336 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_001784186.1 994314 D 228400 CDS YP_001784187.1 170719029 6108678 995352..995828 1 NC_010519.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: hso:HS_1225 flavin:NADH reductase; flavin reductase domain-containing protein 995828 6108678 HSM_0855 Haemophilus somnus 2336 flavin reductase domain-containing protein YP_001784187.1 995352 D 228400 CDS YP_001784188.1 170719030 6108679 complement(995904..996848) 1 NC_010519.1 KEGG: rba:RB9243 hypothetical protein- glycosyltransferase; hypothetical protein 996848 6108679 HSM_0856 Haemophilus somnus 2336 hypothetical protein YP_001784188.1 995904 R 228400 CDS YP_001784189.1 170719031 6108680 complement(997098..998864) 1 NC_010519.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 998864 aspS 6108680 aspS Haemophilus somnus 2336 aspartyl-tRNA synthetase YP_001784189.1 997098 R 228400 CDS YP_001784190.1 170719032 6108681 999010..999750 1 NC_010519.1 TIGRFAM: methyltransferase; PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: hso:HS_1222 SAM-dependent methyltransferase; methyltransferase 999750 6108681 HSM_0858 Haemophilus somnus 2336 methyltransferase YP_001784190.1 999010 D 228400 CDS YP_001784191.1 170719033 6108682 complement(999788..1000636) 1 NC_010519.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1000636 6108682 HSM_0859 Haemophilus somnus 2336 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001784191.1 999788 R 228400 CDS YP_001784192.1 170719035 6108881 complement(1001039..1002094) 1 NC_010519.1 PFAM: phage integrase family protein; KEGG: ecp:ECP_0274 phage integrase; phage integrase family protein 1002094 6108881 HSM_0860 Haemophilus somnus 2336 phage integrase family protein YP_001784192.1 1001039 R 228400 CDS YP_001784193.1 170719036 6108685 complement(1002329..1003426) 1 NC_010519.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: hso:HS_1422 DNA-cytosine methyltransferase; DNA-cytosine methyltransferase 1003426 6108685 HSM_0861 Haemophilus somnus 2336 DNA-cytosine methyltransferase YP_001784193.1 1002329 R 228400 CDS YP_001784194.1 170719037 6108686 complement(1003733..1004233) 1 NC_010519.1 KEGG: hdu:HD0960 hypothetical protein; hypothetical protein 1004233 6108686 HSM_0862 Haemophilus somnus 2336 hypothetical protein YP_001784194.1 1003733 R 228400 CDS YP_001784195.1 170719038 6108687 complement(1004294..1004722) 1 NC_010519.1 KEGG: hso:HS_1421 hypothetical protein; hypothetical protein 1004722 6108687 HSM_0863 Haemophilus somnus 2336 hypothetical protein YP_001784195.1 1004294 R 228400 CDS YP_001784196.1 170719039 6108688 complement(1005041..1005679) 1 NC_010519.1 KEGG: sit:TM1040_1688 hypothetical protein; hypothetical protein 1005679 6108688 HSM_0864 Haemophilus somnus 2336 hypothetical protein YP_001784196.1 1005041 R 228400 CDS YP_001784197.1 170719040 6108689 complement(1005832..1006158) 1 NC_010519.1 KEGG: hso:HS_1418 Haemophilus-specific protein, uncharacterized; hypothetical protein 1006158 6108689 HSM_0865 Haemophilus somnus 2336 hypothetical protein YP_001784197.1 1005832 R 228400 CDS YP_001784198.1 170719041 6108690 complement(1006155..1006592) 1 NC_010519.1 KEGG: hso:HS_1417 Haemophilus-specific protein, uncharacterized; hypothetical protein 1006592 6108690 HSM_0866 Haemophilus somnus 2336 hypothetical protein YP_001784198.1 1006155 R 228400 CDS YP_001784199.1 170719042 6108691 complement(1006589..1006873) 1 NC_010519.1 KEGG: hso:HS_1416 Haemophilus-specific protein, uncharacterized; hypothetical protein 1006873 6108691 HSM_0867 Haemophilus somnus 2336 hypothetical protein YP_001784199.1 1006589 R 228400 CDS YP_001784200.1 170719043 6108692 complement(1006960..1007799) 1 NC_010519.1 KEGG: ecv:APECO1_4215 antirepressor protein; antirepressor protein 1007799 6108692 HSM_0868 Haemophilus somnus 2336 antirepressor protein YP_001784200.1 1006960 R 228400 CDS YP_001784201.1 170719044 6108693 complement(1008591..1009388) 1 NC_010519.1 KEGG: cjr:CJE1430 RloG protein; hypothetical protein 1009388 6108693 HSM_0869 Haemophilus somnus 2336 hypothetical protein YP_001784201.1 1008591 R 228400 CDS YP_001784202.1 170719046 6108694 1009789..1009974 1 NC_010519.1 hypothetical protein 1009974 6108694 HSM_0870 Haemophilus somnus 2336 hypothetical protein YP_001784202.1 1009789 D 228400 CDS YP_001784203.1 170719047 6108696 1010153..1010518 1 NC_010519.1 KEGG: ecp:ECP_4545 hypothetical protein; hypothetical protein 1010518 6108696 HSM_0871 Haemophilus somnus 2336 hypothetical protein YP_001784203.1 1010153 D 228400 CDS YP_001784204.1 170719048 6108697 complement(1010620..1011249) 1 NC_010519.1 KEGG: sgl:SG1183 hypothetical protein; hypothetical protein 1011249 6108697 HSM_0872 Haemophilus somnus 2336 hypothetical protein YP_001784204.1 1010620 R 228400 CDS YP_001784205.1 170719049 6108698 complement(1011246..1011908) 1 NC_010519.1 KEGG: bbr:BB3533 hypothetical protein; hypothetical protein 1011908 6108698 HSM_0873 Haemophilus somnus 2336 hypothetical protein YP_001784205.1 1011246 R 228400 CDS YP_001784206.1 170719050 6108699 complement(1011972..1012604) 1 NC_010519.1 PFAM: KilA domain protein; KEGG: vvu:VV2_0650 hypothetical protein; KilA domain-containing protein 1012604 6108699 HSM_0874 Haemophilus somnus 2336 KilA domain-containing protein YP_001784206.1 1011972 R 228400 CDS YP_001784207.1 170719051 6108700 complement(1012882..1013709) 1 NC_010519.1 KEGG: xft:PD1061 DNA-damage-inducible protein D; hypothetical protein 1013709 6108700 HSM_0875 Haemophilus somnus 2336 hypothetical protein YP_001784207.1 1012882 R 228400 CDS YP_001784208.1 170719052 6108701 complement(1014768..1014989) 1 NC_010519.1 KEGG: hit:NTHI1717 hypothetical protein; hypothetical protein 1014989 6108701 HSM_0876 Haemophilus somnus 2336 hypothetical protein YP_001784208.1 1014768 R 228400 CDS YP_001784209.1 170719053 6108702 1015001..1015189 1 NC_010519.1 PFAM: protein of unknown function DUF1508; KEGG: deh:cbdb_A1247 hypothetical protein; hypothetical protein 1015189 6108702 HSM_0877 Haemophilus somnus 2336 hypothetical protein YP_001784209.1 1015001 D 228400 CDS YP_001784210.1 170719054 6108703 1015606..1015902 1 NC_010519.1 TIGRFAM: Addiction module killer protein HI1419; PFAM: protein of unknown function DUF891; KEGG: hin:HI1419 hypothetical protein; addiction module killer protein 1015902 6108703 HSM_0878 Haemophilus somnus 2336 addiction module killer protein YP_001784210.1 1015606 D 228400 CDS YP_001784211.1 170719055 6108704 1015904..1016200 1 NC_010519.1 TIGRFAM: Addiction module antidote protein HI1420; PFAM: helix-turn-helix domain protein; KEGG: hin:HI1420 hypothetical protein; transcriptional regulator 1016200 6108704 HSM_0879 Haemophilus somnus 2336 transcriptional regulator YP_001784211.1 1015904 D 228400 CDS YP_001784212.1 170719057 6108705 complement(1016228..1017232) 1 NC_010519.1 KEGG: bam:Bamb_0901 hypothetical protein; hypothetical protein 1017232 6108705 HSM_0880 Haemophilus somnus 2336 hypothetical protein YP_001784212.1 1016228 R 228400 CDS YP_001784213.1 170719058 6108707 complement(1017329..1018015) 1 NC_010519.1 PFAM: peptidase S24 S26A and S26B; SMART: helix-turn-helix domain protein; KEGG: bbr:BB1678 phage repressor; prophage repressor 1018015 6108707 HSM_0881 Haemophilus somnus 2336 prophage repressor YP_001784213.1 1017329 R 228400 CDS YP_001784214.1 170719059 6108708 1018118..1018345 1 NC_010519.1 KEGG: ecs:ECs1942 regulatory protein; regulatory protein 1018345 6108708 HSM_0882 Haemophilus somnus 2336 regulatory protein YP_001784214.1 1018118 D 228400 CDS YP_001784215.1 170719060 6108709 1018498..1018737 1 NC_010519.1 KEGG: hso:HS_1403 hypothetical protein; hypothetical protein 1018737 6108709 HSM_0883 Haemophilus somnus 2336 hypothetical protein YP_001784215.1 1018498 D 228400 CDS YP_001784216.1 170719061 6108710 1018727..1019551 1 NC_010519.1 KEGG: hso:HS_1402 hypothetical protein; hypothetical protein 1019551 6108710 HSM_0884 Haemophilus somnus 2336 hypothetical protein YP_001784216.1 1018727 D 228400 CDS YP_001784217.1 170719062 6108711 1019548..1020240 1 NC_010519.1 PFAM: replication P family protein; KEGG: hso:HS_1401 replication protein P; replication P family protein 1020240 6108711 HSM_0885 Haemophilus somnus 2336 replication P family protein YP_001784217.1 1019548 D 228400 CDS YP_001784218.1 170719063 6108712 1020255..1020788 1 NC_010519.1 TIGRFAM: phage N-6-adenine-methyltransferase; PFAM: DNA N-6-adenine-methyltransferase; KEGG: hso:HS_1400 DNA methylase; phage N-6-adenine-methyltransferase 1020788 6108712 HSM_0886 Haemophilus somnus 2336 phage N-6-adenine-methyltransferase YP_001784218.1 1020255 D 228400 CDS YP_001784219.1 170719064 6108713 1020801..1021253 1 NC_010519.1 KEGG: hso:HS_1399 hypothetical protein; hypothetical protein 1021253 6108713 HSM_0887 Haemophilus somnus 2336 hypothetical protein YP_001784219.1 1020801 D 228400 CDS YP_001784220.1 170719065 6108714 complement(1021305..1021919) 1 NC_010519.1 PFAM: BRO domain protein; KEGG: hso:HS_1398 prophage antirepressor; prophage antirepressor 1021919 6108714 HSM_0888 Haemophilus somnus 2336 prophage antirepressor YP_001784220.1 1021305 R 228400 CDS YP_001784221.1 170719066 6108715 complement(1022474..1022887) 1 NC_010519.1 PFAM: protein of unknown function UPF0150; KEGG: hso:HS_1396 hypothetical protein; hypothetical protein 1022887 6108715 HSM_0889 Haemophilus somnus 2336 hypothetical protein YP_001784221.1 1022474 R 228400 CDS YP_001784222.1 170719068 6108716 complement(1022910..1023125) 1 NC_010519.1 PFAM: YcfA family protein; KEGG: hso:HS_1395 hypothetical protein; hypothetical protein 1023125 6108716 HSM_0890 Haemophilus somnus 2336 hypothetical protein YP_001784222.1 1022910 R 228400 CDS YP_001784223.1 170719069 6108718 1023286..1023864 1 NC_010519.1 PFAM: bacteriophage Lambda NinG family protein; KEGG: hso:HS_1394 NinG recombination protein; bacteriophage lambda NinG family protein 1023864 6108718 HSM_0891 Haemophilus somnus 2336 bacteriophage lambda NinG family protein YP_001784223.1 1023286 D 228400 CDS YP_001784224.1 170719070 6108719 complement(1024492..1024896) 1 NC_010519.1 KEGG: nmc:NMC0837 hypothetical protein; hypothetical protein 1024896 6108719 HSM_0892 Haemophilus somnus 2336 hypothetical protein YP_001784224.1 1024492 R 228400 CDS YP_001784225.1 170719071 6108720 1025178..1025414 1 NC_010519.1 KEGG: hso:HS_1389 Haemophilus-specific protein, uncharacterized; hypothetical protein 1025414 6108720 HSM_0893 Haemophilus somnus 2336 hypothetical protein YP_001784225.1 1025178 D 228400 CDS YP_001784226.1 170719072 6108721 1025404..1025943 1 NC_010519.1 PFAM: glycoside hydrolase family 24; KEGG: hso:HS_1388 lysozyme, phage-related lysozyme; glycoside hydrolase family protein 1025943 6108721 HSM_0894 Haemophilus somnus 2336 glycoside hydrolase family protein YP_001784226.1 1025404 D 228400 CDS YP_001784227.1 170719073 6108722 1025916..1026245 1 NC_010519.1 KEGG: hso:HS_1387 hypothetical protein; hypothetical protein 1026245 6108722 HSM_0895 Haemophilus somnus 2336 hypothetical protein YP_001784227.1 1025916 D 228400 CDS YP_001784228.1 170719074 6108723 1026442..1027137 1 NC_010519.1 KEGG: hso:HS_1386 terminase small subunit; terminase small subunit 1027137 6108723 HSM_0896 Haemophilus somnus 2336 terminase small subunit YP_001784228.1 1026442 D 228400 CDS YP_001784229.1 170719075 6108724 1027137..1028684 1 NC_010519.1 KEGG: hso:HS_1385 hypothetical protein; hypothetical protein 1028684 6108724 HSM_0897 Haemophilus somnus 2336 hypothetical protein YP_001784229.1 1027137 D 228400 CDS YP_001784230.1 170719076 6108725 1028686..1030863 1 NC_010519.1 KEGG: hso:HS_1384 Haemophilus-specific protein, uncharacterized; hypothetical protein 1030863 6108725 HSM_0898 Haemophilus somnus 2336 hypothetical protein YP_001784230.1 1028686 D 228400 CDS YP_001784231.1 170719077 6108726 1031022..1031120 1 NC_010519.1 hypothetical protein 1031120 6108726 HSM_0899 Haemophilus somnus 2336 hypothetical protein YP_001784231.1 1031022 D 228400 CDS YP_001784232.1 170719080 6108727 1031495..1031683 1 NC_010519.1 KEGG: hso:HS_1382 phage-related protein; hypothetical protein 1031683 6108727 HSM_0900 Haemophilus somnus 2336 hypothetical protein YP_001784232.1 1031495 D 228400 CDS YP_001784233.1 170719081 6108730 1032458..1033333 1 NC_010519.1 KEGG: ecv:APECO1_4215 antirepressor protein; antirepressor protein 1033333 6108730 HSM_0901 Haemophilus somnus 2336 antirepressor protein YP_001784233.1 1032458 D 228400 CDS YP_001784234.1 170719082 6108731 1033403..1036102 1 NC_010519.1 KEGG: hso:HS_1381 hypothetical protein; hypothetical protein 1036102 6108731 HSM_0902 Haemophilus somnus 2336 hypothetical protein YP_001784234.1 1033403 D 228400 CDS YP_001784235.1 170719083 6108732 1036104..1040183 1 NC_010519.1 KEGG: hso:HS_1381 hypothetical protein; hypothetical protein 1040183 6108732 HSM_0903 Haemophilus somnus 2336 hypothetical protein YP_001784235.1 1036104 D 228400 CDS YP_001784236.1 170719084 6108733 1040446..1040748 1 NC_010519.1 KEGG: hso:HS_1380 transcription regulator; XRE family transcriptional regulator 1040748 6108733 HSM_0904 Haemophilus somnus 2336 XRE family transcriptional regulator YP_001784236.1 1040446 D 228400 CDS YP_001784237.1 170719085 6108734 1040833..1041027 1 NC_010519.1 KEGG: hso:HS_1379 Haemophilus-specific protein, uncharacterized; hypothetical protein 1041027 6108734 HSM_0905 Haemophilus somnus 2336 hypothetical protein YP_001784237.1 1040833 D 228400 CDS YP_001784238.1 170719086 6108735 1041105..1041968 1 NC_010519.1 KEGG: hso:HS_1378 hypothetical protein; hypothetical protein 1041968 6108735 HSM_0906 Haemophilus somnus 2336 hypothetical protein YP_001784238.1 1041105 D 228400 CDS YP_001784239.1 170719087 6108736 1041994..1042989 1 NC_010519.1 KEGG: hso:HS_1377 hypothetical protein; hypothetical protein 1042989 6108736 HSM_0907 Haemophilus somnus 2336 hypothetical protein YP_001784239.1 1041994 D 228400 CDS YP_001784240.1 170719088 6108737 1043051..1043497 1 NC_010519.1 KEGG: hso:HS_1376 Haemophilus-specific protein, uncharacterized; hypothetical protein 1043497 6108737 HSM_0908 Haemophilus somnus 2336 hypothetical protein YP_001784240.1 1043051 D 228400 CDS YP_001784241.1 170719089 6108738 1043494..1043883 1 NC_010519.1 KEGG: hso:HS_1375 Haemophilus-specific protein, uncharacterized; hypothetical protein 1043883 6108738 HSM_0909 Haemophilus somnus 2336 hypothetical protein YP_001784241.1 1043494 D 228400 CDS YP_001784242.1 170719091 6108739 1044147..1046126 1 NC_010519.1 KEGG: hso:HS_1373 Haemophilus-specific protein, uncharacterized; hypothetical protein 1046126 6108739 HSM_0910 Haemophilus somnus 2336 hypothetical protein YP_001784242.1 1044147 D 228400 CDS YP_001784243.1 170719092 6108741 1046119..1047498 1 NC_010519.1 KEGG: hso:HS_1372 phage-related tail fiber protein; hypothetical protein 1047498 6108741 HSM_0911 Haemophilus somnus 2336 hypothetical protein YP_001784243.1 1046119 D 228400 CDS YP_001784244.1 170719093 6108742 complement(1047495..1047842) 1 NC_010519.1 PFAM: helix-turn-helix domain protein; KEGG: xfa:XF0534 hypothetical protein; XRE family transcriptional regulator 1047842 6108742 HSM_0912 Haemophilus somnus 2336 XRE family transcriptional regulator YP_001784244.1 1047495 R 228400 CDS YP_001784245.1 170719094 6108743 complement(1047826..1048077) 1 NC_010519.1 KEGG: tde:TDE1648 hypothetical protein; hypothetical protein 1048077 6108743 HSM_0913 Haemophilus somnus 2336 hypothetical protein YP_001784245.1 1047826 R 228400 CDS YP_001784246.1 170719095 6108744 1048140..1048766 1 NC_010519.1 KEGG: nme:NMB1119 hypothetical protein; hypothetical protein 1048766 6108744 HSM_0914 Haemophilus somnus 2336 hypothetical protein YP_001784246.1 1048140 D 228400 CDS YP_001784247.1 170719096 6108745 1048759..1049028 1 NC_010519.1 KEGG: hso:HS_1370 hypothetical protein; hypothetical protein 1049028 6108745 HSM_0915 Haemophilus somnus 2336 hypothetical protein YP_001784247.1 1048759 D 228400 CDS YP_001784248.1 170719097 6108746 1049156..1049800 1 NC_010519.1 KEGG: hso:HS_1369 hypothetical protein; hypothetical protein 1049800 6108746 HSM_0916 Haemophilus somnus 2336 hypothetical protein YP_001784248.1 1049156 D 228400 CDS YP_001784249.1 170719098 6108747 1049797..1050114 1 NC_010519.1 KEGG: hso:HS_1368 Haemophilus-specific protein, uncharacterized; hypothetical protein 1050114 6108747 HSM_0917 Haemophilus somnus 2336 hypothetical protein YP_001784249.1 1049797 D 228400 CDS YP_001784250.1 170719099 6108748 1050117..1051313 1 NC_010519.1 KEGG: hso:HS_1367 Haemophilus-specific protein, uncharacterized; hypothetical protein 1051313 6108748 HSM_0918 Haemophilus somnus 2336 hypothetical protein YP_001784250.1 1050117 D 228400 CDS YP_001784251.1 170719100 6108749 1051332..1051865 1 NC_010519.1 KEGG: hso:HS_1366 Haemophilus-specific protein, uncharacterized; hypothetical protein 1051865 6108749 HSM_0919 Haemophilus somnus 2336 hypothetical protein YP_001784251.1 1051332 D 228400 CDS YP_001784252.1 170719102 6108750 1051865..1052491 1 NC_010519.1 KEGG: hso:HS_1365 Haemophilus-specific protein, uncharacterized; hypothetical protein 1052491 6108750 HSM_0920 Haemophilus somnus 2336 hypothetical protein YP_001784252.1 1051865 D 228400 CDS YP_001784253.1 170719103 6108752 1053004..1053252 1 NC_010519.1 PFAM: phage virion morphogenesis ( tail completion) protein; KEGG: hit:NTHI1873 probable bacteriophage tail completion protein gpS homolog; phage virion morphogenesis ( tail completion) protein 1053252 6108752 HSM_0921 Haemophilus somnus 2336 phage virion morphogenesis ( tail completion) protein YP_001784253.1 1053004 D 228400 CDS YP_001784254.1 170719104 6108753 complement(1053507..1053884) 1 NC_010519.1 hypothetical protein 1053884 6108753 HSM_0922 Haemophilus somnus 2336 hypothetical protein YP_001784254.1 1053507 R 228400 CDS YP_001784255.1 170719105 6108754 complement(1053982..1054251) 1 NC_010519.1 KEGG: hin:HI1501 hypothetical protein HI1501; hypothetical protein 1054251 6108754 HSM_0923 Haemophilus somnus 2336 hypothetical protein YP_001784255.1 1053982 R 228400 CDS YP_001784256.1 170719106 6108755 complement(1054309..1055247) 1 NC_010519.1 acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1055247 6108755 HSM_0924 Haemophilus somnus 2336 lipid A biosynthesis lauroyl acyltransferase YP_001784256.1 1054309 R 228400 CDS YP_001784257.1 170719107 6108756 1055370..1056800 1 NC_010519.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 1056800 6108756 HSM_0925 Haemophilus somnus 2336 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_001784257.1 1055370 D 228400 CDS YP_001784258.1 170719108 6108757 1056810..1057154 1 NC_010519.1 PFAM: arsenate reductase; KEGG: hso:HS_0577 arsenate reductase; arsenate reductase 1057154 6108757 HSM_0926 Haemophilus somnus 2336 arsenate reductase YP_001784258.1 1056810 D 228400 CDS YP_001784259.1 170719109 6108758 1057267..1058400 1 NC_010519.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 1058400 6108758 HSM_0927 Haemophilus somnus 2336 succinyl-diaminopimelate desuccinylase YP_001784259.1 1057267 D 228400 CDS YP_001784260.1 170719110 6108759 1058390..1059070 1 NC_010519.1 PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: hso:HS_0579 D-alanyl-D-alanine carboxypeptidase-related protein; peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin 1059070 6108759 HSM_0928 Haemophilus somnus 2336 peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin YP_001784260.1 1058390 D 228400 CDS YP_001784261.1 170719111 6108760 1059123..1059743 1 NC_010519.1 PFAM: NUDIX hydrolase; KEGG: hso:HS_0580 ADP-ribose diphosphatase; ADP-ribose diphosphatase 1059743 6108760 HSM_0929 Haemophilus somnus 2336 ADP-ribose diphosphatase YP_001784261.1 1059123 D 228400 CDS YP_001784262.1 170719113 6108761 1059882..1060712 1 NC_010519.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase domain protein; KEGG: hso:HS_0581 3',5'-cyclic-nucleotide phosphodiesterase; cyclic 3',5'-adenosine monophosphate phosphodiesterase 1060712 6108761 HSM_0930 Haemophilus somnus 2336 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_001784262.1 1059882 D 228400 CDS YP_001784263.1 170719114 6108763 complement(1060790..1062568) 1 NC_010519.1 PFAM: TonB-dependent receptor; KEGG: hso:HS_0582 transferrin binding protein A; TonB-dependent receptor 1062568 6108763 HSM_0931 Haemophilus somnus 2336 TonB-dependent receptor YP_001784263.1 1060790 R 228400 CDS YP_001784264.1 170719115 6108764 complement(1062508..1063182) 1 NC_010519.1 PFAM: TonB-dependent receptor plug; KEGG: hso:HS_0582 transferrin binding protein A; TonB-dependent receptor plug 1063182 6108764 HSM_0932 Haemophilus somnus 2336 TonB-dependent receptor plug YP_001784264.1 1062508 R 228400 CDS YP_001784265.1 170719116 6108765 complement(1063308..1064435) 1 NC_010519.1 PFAM: inner-membrane translocator; KEGG: hso:HS_0584 D-xylose ABC transporter permease; monosaccharide-transporting ATPase 1064435 6108765 HSM_0933 Haemophilus somnus 2336 monosaccharide-transporting ATPase YP_001784265.1 1063308 R 228400 CDS YP_001784266.1 170719117 6108766 complement(1064439..1065953) 1 NC_010519.1 with XylFH is part of the high affinity xylose ABC transporter; xylose ABC transporter ATP-binding protein 1065953 6108766 HSM_0934 Haemophilus somnus 2336 xylose ABC transporter ATP-binding protein YP_001784266.1 1064439 R 228400 CDS YP_001784267.1 170719118 6108767 complement(1066013..1067014) 1 NC_010519.1 periplasmic substrate-binding component of the ATP-dependent xylose transporter; high affinity; sugar ABC transporter substrate-binding protein 1067014 xylF 6108767 xylF Haemophilus somnus 2336 sugar ABC transporter substrate-binding protein YP_001784267.1 1066013 R 228400 CDS YP_001784268.1 170719119 6108768 1067268..1068587 1 NC_010519.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 1068587 6108768 HSM_0936 Haemophilus somnus 2336 xylose isomerase YP_001784268.1 1067268 D 228400 CDS YP_001784269.1 170719120 6108769 1068656..1070116 1 NC_010519.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_0588 xylulokinase (xylulose kinase); xylulokinase 1070116 6108769 HSM_0937 Haemophilus somnus 2336 xylulokinase YP_001784269.1 1068656 D 228400 CDS YP_001784270.1 170719121 6108770 complement(1070247..1071413) 1 NC_010519.1 PFAM: Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0602 adhesin; hemagluttinin domain-containing protein 1071413 6108770 HSM_0938 Haemophilus somnus 2336 hemagluttinin domain-containing protein YP_001784270.1 1070247 R 228400 CDS YP_001784271.1 170719122 6108771 complement(1071701..1072495) 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0590 peptide ABC transporter ATP-binding protein; ABC transporter 1072495 6108771 HSM_0939 Haemophilus somnus 2336 ABC transporter YP_001784271.1 1071701 R 228400 CDS YP_001784272.1 170719124 6108772 complement(1072511..1073557) 1 NC_010519.1 TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: hso:HS_0591 peptide ABC transporter ATP-binding protein; oligopeptide/dipeptide ABC transporter ATPase 1073557 6108772 HSM_0940 Haemophilus somnus 2336 oligopeptide/dipeptide ABC transporter ATPase YP_001784272.1 1072511 R 228400 CDS YP_001784273.1 170719125 6108774 complement(1073569..1074456) 1 NC_010519.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0592 peptide ABC transporter permease; binding-protein-dependent transporters inner membrane component 1074456 6108774 HSM_0941 Haemophilus somnus 2336 binding-protein-dependent transporters inner membrane component YP_001784273.1 1073569 R 228400 CDS YP_001784274.1 170719126 6108775 complement(1074446..1075411) 1 NC_010519.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0593 peptide ABC transporter permease; binding-protein-dependent transporters inner membrane component 1075411 6108775 HSM_0942 Haemophilus somnus 2336 binding-protein-dependent transporters inner membrane component YP_001784274.1 1074446 R 228400 CDS YP_001784275.1 170719127 6108776 complement(1075439..1077127) 1 NC_010519.1 PFAM: extracellular solute-binding protein family 5; KEGG: hso:HS_0594 peptide ABC transporter periplasmic-binding protein; 4-phytase 1077127 6108776 HSM_0943 Haemophilus somnus 2336 4-phytase YP_001784275.1 1075439 R 228400 CDS YP_001784276.1 170719128 6108777 1077194..1078603 1 NC_010519.1 PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: hso:HS_0595 conserved hypothetical protein; hypothetical protein 1078603 6108777 HSM_0944 Haemophilus somnus 2336 hypothetical protein YP_001784276.1 1077194 D 228400 CDS YP_001784277.1 170719129 6108778 1078613..1079686 1 NC_010519.1 PFAM: conserved hypothetical protein 1620; KEGG: hso:HS_0596 hypothetical protein; hypothetical protein 1079686 6108778 HSM_0945 Haemophilus somnus 2336 hypothetical protein YP_001784277.1 1078613 D 228400 CDS YP_001784278.1 170719130 6108779 complement(1079793..1080056) 1 NC_010519.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1080056 grxA 6108779 grxA Haemophilus somnus 2336 glutaredoxin YP_001784278.1 1079793 R 228400 CDS YP_001784279.1 170719131 6108780 complement(1080177..1082420) 1 NC_010519.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1082420 6108780 HSM_0947 Haemophilus somnus 2336 DNA topoisomerase IV subunit A YP_001784279.1 1080177 R 228400 CDS YP_001784280.1 170719132 6108781 complement(1082466..1083587) 1 NC_010519.1 KEGG: nmc:NMC0772 type II restriction endonuclease; type II restriction endonuclease 1083587 6108781 HSM_0948 Haemophilus somnus 2336 type II restriction endonuclease YP_001784280.1 1082466 R 228400 CDS YP_001784281.1 170719133 6108782 complement(1083592..1084818) 1 NC_010519.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: nmc:NMC0771 modification methylase; DNA-cytosine methyltransferase 1084818 6108782 HSM_0949 Haemophilus somnus 2336 DNA-cytosine methyltransferase YP_001784281.1 1083592 R 228400 CDS YP_001784282.1 170719135 6108783 complement(1084869..1086761) 1 NC_010519.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1086761 6108783 HSM_0950 Haemophilus somnus 2336 DNA topoisomerase IV subunit B YP_001784282.1 1084869 R 228400 CDS YP_001784283.1 170719136 6108785 complement(1086817..1088103) 1 NC_010519.1 TIGRFAM: AmpG-related permease; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_0600 AmpG protein; AmpG-like permease 1088103 6108785 HSM_0951 Haemophilus somnus 2336 AmpG-like permease YP_001784283.1 1086817 R 228400 CDS YP_001784284.1 170719137 6108786 1088285..1089598 1 NC_010519.1 PFAM: xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: hso:HS_0601 conserved permease, xanthine/uracil family; xanthine/uracil/vitamin C permease 1089598 6108786 HSM_0952 Haemophilus somnus 2336 xanthine/uracil/vitamin C permease YP_001784284.1 1088285 D 228400 CDS YP_001784285.1 170719138 6108787 complement(1089705..1090931) 1 NC_010519.1 PFAM: Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0602 adhesin; hemagluttinin domain-containing protein 1090931 6108787 HSM_0953 Haemophilus somnus 2336 hemagluttinin domain-containing protein YP_001784285.1 1089705 R 228400 CDS YP_001784286.1 170719139 6108883 complement(1091496..1092254) 1 NC_010519.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1092254 6108883 HSM_0954 Haemophilus somnus 2336 DNA polymerase III subunit epsilon YP_001784286.1 1091496 R 228400 CDS YP_001784287.1 170719140 6108789 1092325..1092789 1 NC_010519.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 1092789 rnhA 6108789 rnhA Haemophilus somnus 2336 ribonuclease H YP_001784287.1 1092325 D 228400 CDS YP_001784288.1 170719141 6108790 complement(1092864..1094069) 1 NC_010519.1 TIGRFAM: mannose-6-phosphate isomerase, class I; KEGG: hso:HS_0605 mannose-6-phosphate isomerase (phosphomannose isomerase); mannose-6-phosphate isomerase 1094069 6108790 HSM_0956 Haemophilus somnus 2336 mannose-6-phosphate isomerase YP_001784288.1 1092864 R 228400 CDS YP_001784289.1 170719142 6108791 complement(1094066..1094545) 1 NC_010519.1 KEGG: hso:HS_0606 hypothetical protein; hypothetical protein 1094545 6108791 HSM_0957 Haemophilus somnus 2336 hypothetical protein YP_001784289.1 1094066 R 228400 CDS YP_001784290.1 170719143 6108792 complement(1094603..1095439) 1 NC_010519.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 1095439 6108792 HSM_0958 Haemophilus somnus 2336 PTS system mannose-specific transporter subunit IID YP_001784290.1 1094603 R 228400 CDS YP_001784291.1 170719144 6108793 complement(1095454..1096254) 1 NC_010519.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; KEGG: hso:HS_0608 protein-N(pi)-phosphohistidine-sugar phosphotransferase (mannose-specific phosphotransferase system IIC component); PTS system mannose/fructose/sorbose family transporter subunit IIC 1096254 6108793 HSM_0959 Haemophilus somnus 2336 PTS system mannose/fructose/sorbose family transporter subunit IIC YP_001784291.1 1095454 R 228400 CDS YP_001784292.1 170719146 6108794 complement(1096266..1097237) 1 NC_010519.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PTS system, mannose/fructose/sorbose family, IIsubunit alpha; KEGG: hso:HS_0609 protein-N(pi)-phosphohistidine-sugar phosphotransferase (phosphotransferase system mannose/fructose-specific IIA component); PTS system mannose/fructose/sorbose family subunit IIB 1097237 6108794 HSM_0960 Haemophilus somnus 2336 PTS system mannose/fructose/sorbose family subunit IIB YP_001784292.1 1096266 R 228400 CDS YP_001784293.1 170719147 6108796 complement(1097447..1097809) 1 NC_010519.1 PFAM: protein of unknown function DUF496; KEGG: hso:HS_0610 hypothetical protein; hypothetical protein 1097809 6108796 HSM_0961 Haemophilus somnus 2336 hypothetical protein YP_001784293.1 1097447 R 228400 CDS YP_001784294.1 170719148 6108797 1097999..1099078 1 NC_010519.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1099078 6108797 HSM_0962 Haemophilus somnus 2336 phosphoserine aminotransferase YP_001784294.1 1097999 D 228400 CDS YP_001784295.1 170719149 6108798 1099137..1100246 1 NC_010519.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1100246 6108798 HSM_0963 Haemophilus somnus 2336 histidinol-phosphate aminotransferase YP_001784295.1 1099137 D 228400 CDS YP_001784296.1 170719150 6108799 1100309..1101607 1 NC_010519.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1101607 6108799 HSM_0964 Haemophilus somnus 2336 3-phosphoshikimate 1-carboxyvinyltransferase YP_001784296.1 1100309 D 228400 CDS YP_001784297.1 170719151 6108800 1101843..1103057 1 NC_010519.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: hso:HS_0614 membrane fusion protein; RND family efflux transporter MFP subunit 1103057 6108800 HSM_0965 Haemophilus somnus 2336 RND family efflux transporter MFP subunit YP_001784297.1 1101843 D 228400 CDS YP_001784298.1 170719152 6108801 1103079..1106195 1 NC_010519.1 PFAM: acriflavin resistance protein; KEGG: hso:HS_0615 cation/multidrug efflux protein; acriflavin resistance protein 1106195 6108801 HSM_0966 Haemophilus somnus 2336 acriflavin resistance protein YP_001784298.1 1103079 D 228400 CDS YP_001784299.1 170719153 6108802 complement(1106221..1106979) 1 NC_010519.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB 1106979 6108802 HSM_0967 Haemophilus somnus 2336 acyl-CoA thioester hydrolase YfbB YP_001784299.1 1106221 R 228400 CDS YP_001784300.1 170719154 6108803 complement(1106992..1108698) 1 NC_010519.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 1108698 6108803 HSM_0968 Haemophilus somnus 2336 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_001784300.1 1106992 R 228400 CDS YP_001784301.1 170719155 6108804 complement(1108704..1110011) 1 NC_010519.1 TIGRFAM: isochorismate synthase; PFAM: anthranilate synthase component I and chorismate binding protein; KEGG: hso:HS_0618 isochorismate synthase; isochorismate synthase 1110011 6108804 HSM_0969 Haemophilus somnus 2336 isochorismate synthase YP_001784301.1 1108704 R 228400 CDS YP_001784302.1 170719157 6108805 1110139..1111353 1 NC_010519.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 1111353 6108805 HSM_0970 Haemophilus somnus 2336 aminotransferase AlaT YP_001784302.1 1110139 D 228400 CDS YP_001784303.1 170719158 6108807 complement(1111398..1112138) 1 NC_010519.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1112138 6108807 HSM_0971 Haemophilus somnus 2336 fatty acid metabolism regulator YP_001784303.1 1111398 R 228400 CDS YP_001784304.1 170719159 6108808 1112308..1112841 1 NC_010519.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1112841 6108808 HSM_0972 Haemophilus somnus 2336 disulfide bond formation protein B YP_001784304.1 1112308 D 228400 CDS YP_001784305.1 170719160 6108810 complement(1114012..1114707) 1 NC_010519.1 KEGG: pmu:PM1140 glycosyl transferase; glycosyl transferase family protein 1114707 6108810 HSM_0975 Haemophilus somnus 2336 glycosyl transferase family protein YP_001784305.1 1114012 R 228400 CDS YP_001784306.1 170719161 6108811 complement(1114845..1115036) 1 NC_010519.1 KEGG: hdu:HD0466 lipooligosaccharide N-acetylglucosamine glycosyltransferase; cell wall biogenesis glycosyltransferase-like protein 1115036 6108811 HSM_0976 Haemophilus somnus 2336 cell wall biogenesis glycosyltransferase-like protein YP_001784306.1 1114845 R 228400 CDS YP_001784307.1 170719162 6108812 complement(1115051..1115884) 1 NC_010519.1 PFAM: glycosyl transferase family 25; KEGG: hit:NTHI0677 UDP-Gal--lipooligosaccharide galactosyltransferase; glycosyl transferase family protein 1115884 6108812 HSM_0977 Haemophilus somnus 2336 glycosyl transferase family protein YP_001784307.1 1115051 R 228400 CDS YP_001784308.1 170719163 6108813 complement(1115946..1116761) 1 NC_010519.1 PFAM: glycosyl transferase family 25; KEGG: hdu:HD0472 lipooligosaccharide galactosyltransferase II; glycosyl transferase family protein 1116761 6108813 HSM_0978 Haemophilus somnus 2336 glycosyl transferase family protein YP_001784308.1 1115946 R 228400 CDS YP_001784309.1 170719164 6108814 1116883..1117764 1 NC_010519.1 PFAM: glycosyl transferase family 25; KEGG: hso:HS_0638 Lob1 protein; glycosyl transferase family protein 1117764 6108814 HSM_0979 Haemophilus somnus 2336 glycosyl transferase family protein YP_001784309.1 1116883 D 228400 CDS YP_001784310.1 170719166 6108815 complement(1117902..1118951) 1 NC_010519.1 Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding subunit 1118951 fbpC 6108815 fbpC Haemophilus somnus 2336 ferric transporter ATP-binding subunit YP_001784310.1 1117902 R 228400 CDS YP_001784311.1 170719167 6108817 complement(1119018..1121075) 1 NC_010519.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0640 Fe3+ ABC transporter permease; binding-protein-dependent transporters inner membrane component 1121075 6108817 HSM_0981 Haemophilus somnus 2336 binding-protein-dependent transporters inner membrane component YP_001784311.1 1119018 R 228400 CDS YP_001784312.1 170719168 6108818 complement(1121097..1122128) 1 NC_010519.1 PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_0641 Fe3+ ABC transporter iron-binding protein; extracellular solute-binding protein 1122128 6108818 HSM_0982 Haemophilus somnus 2336 extracellular solute-binding protein YP_001784312.1 1121097 R 228400 CDS YP_001784313.1 170719169 6108819 complement(1122156..1123196) 1 NC_010519.1 PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_0643 Fe3+ ABC transporter iron-binding protein; extracellular solute-binding protein 1123196 6108819 HSM_0983 Haemophilus somnus 2336 extracellular solute-binding protein YP_001784313.1 1122156 R 228400 CDS YP_001784314.1 170719170 6108820 1123400..1124041 1 NC_010519.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1124041 6108820 HSM_0984 Haemophilus somnus 2336 uridine kinase YP_001784314.1 1123400 D 228400 CDS YP_001784315.1 170719171 6108821 1124051..1124635 1 NC_010519.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 1124635 dcd 6108821 dcd Haemophilus somnus 2336 deoxycytidine triphosphate deaminase YP_001784315.1 1124051 D 228400 CDS YP_001784316.1 170719172 6108822 1124650..1125843 1 NC_010519.1 KEGG: hso:HS_0646 hypothetical protein; hypothetical protein 1125843 6108822 HSM_0986 Haemophilus somnus 2336 hypothetical protein YP_001784316.1 1124650 D 228400 CDS YP_001784317.1 170719173 6108823 1126121..1127122 1 NC_010519.1 PFAM: sodium symporter; KEGG: hso:HS_0647 sodium-dependent transporter; bile acid:sodium symporter 1127122 6108823 HSM_0987 Haemophilus somnus 2336 bile acid:sodium symporter YP_001784317.1 1126121 D 228400 CDS YP_001784318.1 170719174 6108824 1127212..1127856 1 NC_010519.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1127856 adk 6108824 adk Haemophilus somnus 2336 adenylate kinase YP_001784318.1 1127212 D 228400 CDS YP_001784319.1 170719175 6108825 complement(1127942..1128529) 1 NC_010519.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 1128529 6108825 HSM_0989 Haemophilus somnus 2336 heat shock protein GrpE YP_001784319.1 1127942 R 228400 CDS YP_001784320.1 170719177 6108826 1128672..1129589 1 NC_010519.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1129589 ppnK 6108826 ppnK Haemophilus somnus 2336 inorganic polyphosphate/ATP-NAD kinase YP_001784320.1 1128672 D 228400 CDS YP_001784321.1 170719178 6108828 1129667..1131346 1 NC_010519.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: hso:HS_0651 DNA repair protein; DNA repair protein RecN 1131346 6108828 HSM_0991 Haemophilus somnus 2336 DNA repair protein RecN YP_001784321.1 1129667 D 228400 CDS YP_001784322.1 170719179 6108829 complement(1131537..1132847) 1 NC_010519.1 PFAM: sodium/hydrogen exchanger; KEGG: hso:HS_0652 Na+/H+ antiporter; sodium/hydrogen exchanger 1132847 6108829 HSM_0992 Haemophilus somnus 2336 sodium/hydrogen exchanger YP_001784322.1 1131537 R 228400 CDS YP_001784323.1 170719180 6108830 complement(1133175..1133525) 1 NC_010519.1 PFAM: endoribonuclease L-PSP; KEGG: hso:HS_0653 translation inhibitor of mRNA; endoribonuclease L-PSP 1133525 6108830 HSM_0993 Haemophilus somnus 2336 endoribonuclease L-PSP YP_001784323.1 1133175 R 228400 CDS YP_001784324.1 170719181 6108831 1133636..1134358 1 NC_010519.1 KEGG: hso:HS_0654 hypothetical protein; hypothetical protein 1134358 6108831 HSM_0994 Haemophilus somnus 2336 hypothetical protein YP_001784324.1 1133636 D 228400 CDS YP_001784325.1 170719182 6108832 1134373..1135272 1 NC_010519.1 TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; KEGG: hso:HS_0655 ribosomal protein S6 modification protein; alpha-L-glutamate ligase 1135272 6108832 HSM_0995 Haemophilus somnus 2336 alpha-L-glutamate ligase YP_001784325.1 1134373 D 228400 CDS YP_001784326.1 170719183 6108833 1135391..1136386 1 NC_010519.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1136386 lpxK 6108833 lpxK Haemophilus somnus 2336 tetraacyldisaccharide 4'-kinase YP_001784326.1 1135391 D 228400 CDS YP_001784327.1 170719184 6108834 1136383..1136580 1 NC_010519.1 PFAM: protein of unknown function DUF343; KEGG: hso:HS_0657 hypothetical protein; hypothetical protein 1136580 6108834 HSM_0997 Haemophilus somnus 2336 hypothetical protein YP_001784327.1 1136383 D 228400 CDS YP_001784328.1 170719185 6108835 1136595..1137365 1 NC_010519.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1137365 6108835 HSM_0998 Haemophilus somnus 2336 3-deoxy-manno-octulosonate cytidylyltransferase YP_001784328.1 1136595 D 228400 CDS YP_001784329.1 170719186 6108836 1137358..1139187 1 NC_010519.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1139187 uvrC 6108836 uvrC Haemophilus somnus 2336 excinuclease ABC subunit C YP_001784329.1 1137358 D 228400 CDS YP_001784330.1 170717210 6108837 complement(1139253..1139639) 1 NC_010519.1 PFAM: hypothetical protein?; KEGG: hso:HS_0660 membrane protein; TM2 domain-containing protein 1139639 6108837 HSM_1000 Haemophilus somnus 2336 TM2 domain-containing protein YP_001784330.1 1139253 R 228400 CDS YP_001784331.1 170717211 6106842 complement(1139764..1141743) 1 NC_010519.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1141743 6106842 HSM_1001 Haemophilus somnus 2336 exoribonuclease II YP_001784331.1 1139764 R 228400 CDS YP_001784332.1 170717212 6106843 complement(1141808..1142596) 1 NC_010519.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: hso:HS_0662 enoyl-[acyl-carrier-protein] reductase (NADH); short-chain dehydrogenase/reductase SDR 1142596 6106843 HSM_1002 Haemophilus somnus 2336 short-chain dehydrogenase/reductase SDR YP_001784332.1 1141808 R 228400 CDS YP_001784333.1 170717213 6106844 complement(1142687..1143454) 1 NC_010519.1 PFAM: protein of unknown function DUF34; KEGG: hso:HS_0663 hypothetical protein; hypothetical protein 1143454 6106844 HSM_1003 Haemophilus somnus 2336 hypothetical protein YP_001784333.1 1142687 R 228400 CDS YP_001784334.1 170717214 6106845 complement(1143466..1145496) 1 NC_010519.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 1145496 mnmC 6106845 mnmC Haemophilus somnus 2336 5-methylaminomethyl-2-thiouridine methyltransferase YP_001784334.1 1143466 R 228400 CDS YP_001784335.1 170717215 6106846 1145651..1146871 1 NC_010519.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1146871 6106846 HSM_1005 Haemophilus somnus 2336 3-oxoacyl-ACP synthase YP_001784335.1 1145651 D 228400 CDS YP_001784336.1 170717216 6106847 1147290..1148618 1 NC_010519.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: hso:HS_1101 ammonium transporter; ammonium transporter 1148618 6106847 HSM_1006 Haemophilus somnus 2336 ammonium transporter YP_001784336.1 1147290 D 228400 CDS YP_001784337.1 170717217 6108884 complement(1149663..1150217) 1 NC_010519.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1150217 6108884 HSM_1007 Haemophilus somnus 2336 oligoribonuclease YP_001784337.1 1149663 R 228400 CDS YP_001784338.1 170717218 6106849 1150287..1151339 1 NC_010519.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 1151339 6106849 HSM_1008 Haemophilus somnus 2336 ribosome-associated GTPase YP_001784338.1 1150287 D 228400 CDS YP_001784339.1 170717219 6106850 1151562..1151819 1 NC_010519.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: hso:HS_1098 phosphocarrier protein HPr; phosphotransferase system, phosphocarrier protein HPr 1151819 6106850 HSM_1009 Haemophilus somnus 2336 phosphotransferase system, phosphocarrier protein HPr YP_001784339.1 1151562 D 228400 CDS YP_001784340.1 170717221 6106851 1151924..1153651 1 NC_010519.1 phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transporter; phosphoenolpyruvate-protein phosphotransferase 1153651 6106851 HSM_1010 Haemophilus somnus 2336 phosphoenolpyruvate-protein phosphotransferase YP_001784340.1 1151924 D 228400 CDS YP_001784341.1 170717222 6106853 1153714..1154214 1 NC_010519.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 1154214 6106853 HSM_1011 Haemophilus somnus 2336 PTS system glucose-specific transporter YP_001784341.1 1153714 D 228400 CDS YP_001784342.1 170717223 6106854 1154509..1157172 1 NC_010519.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 1157172 aceE 6106854 aceE Haemophilus somnus 2336 pyruvate dehydrogenase subunit E1 YP_001784342.1 1154509 D 228400 CDS YP_001784343.1 170717224 6106855 1157227..1159113 1 NC_010519.1 TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: hso:HS_1094 pyruvate dehydrogenase, E2 complex; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 1159113 6106855 HSM_1013 Haemophilus somnus 2336 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase YP_001784343.1 1157227 D 228400 CDS YP_001784344.1 170717225 6106856 1159197..1160621 1 NC_010519.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1160621 6106856 HSM_1014 Haemophilus somnus 2336 dihydrolipoamide dehydrogenase YP_001784344.1 1159197 D 228400 CDS YP_001784345.1 170717226 6106857 complement(1160710..1161162) 1 NC_010519.1 KEGG: hso:HS_1092 ImpA protein; ImpA protein 1161162 6106857 HSM_1015 Haemophilus somnus 2336 ImpA protein YP_001784345.1 1160710 R 228400 CDS YP_001784346.1 170717227 6106858 1161421..1162662 1 NC_010519.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 1162662 6106858 HSM_1016 Haemophilus somnus 2336 serine/threonine transporter SstT YP_001784346.1 1161421 D 228400 CDS YP_001784347.1 170717228 6106859 1162976..1163296 1 NC_010519.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 1163296 6106859 HSM_1017 Haemophilus somnus 2336 Trp operon repressor YP_001784347.1 1162976 D 228400 CDS YP_001784348.1 170717229 6106860 complement(1163470..1164321) 1 NC_010519.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1164321 tsf 6106860 tsf Haemophilus somnus 2336 elongation factor Ts YP_001784348.1 1163470 R 228400 CDS YP_001784349.1 170717230 6106861 complement(1164444..1165163) 1 NC_010519.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1165163 rpsB 6106861 rpsB Haemophilus somnus 2336 30S ribosomal protein S2 YP_001784349.1 1164444 R 228400 CDS YP_001784350.1 170717232 6106862 complement(1165418..1167274) 1 NC_010519.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: hso:HS_1087 peptidyl-prolyl cis-trans isomerase D; PpiC-type peptidyl-prolyl cis-trans isomerase 1167274 6106862 HSM_1020 Haemophilus somnus 2336 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001784350.1 1165418 R 228400 CDS YP_001784351.1 170717233 6106864 complement(1167566..1169005) 1 NC_010519.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1169005 6106864 HSM_1021 Haemophilus somnus 2336 pyruvate kinase YP_001784351.1 1167566 R 228400 CDS YP_001784352.1 170717234 6106865 complement(1169291..1180540) 1 NC_010519.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1085 large adhesin; YadA domain-containing protein 1180540 6106865 HSM_1022 Haemophilus somnus 2336 YadA domain-containing protein YP_001784352.1 1169291 R 228400 CDS YP_001784353.1 170717235 6106866 complement(1181063..1181629) 1 NC_010519.1 TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: hso:HS_1153 phosphatidylglycerophosphate synthase; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1181629 6106866 HSM_1023 Haemophilus somnus 2336 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_001784353.1 1181063 R 228400 CDS YP_001784354.1 170717236 6106867 complement(1181720..1182592) 1 NC_010519.1 PFAM: protein of unknown function DUF455; KEGG: hso:HS_1152 hypothetical protein; hypothetical protein 1182592 6106867 HSM_1024 Haemophilus somnus 2336 hypothetical protein YP_001784354.1 1181720 R 228400 CDS YP_001784355.1 170717237 6108885 complement(1182884..1183225) 1 NC_010519.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: hso:HS_1151 hypothetical protein; alkylhydroperoxidase 1183225 6108885 HSM_1025 Haemophilus somnus 2336 alkylhydroperoxidase YP_001784355.1 1182884 R 228400 CDS YP_001784356.1 170717238 6106869 complement(1183330..1185060) 1 NC_010519.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1185060 6106869 HSM_1026 Haemophilus somnus 2336 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_001784356.1 1183330 R 228400 CDS YP_001784357.1 170717239 6106870 complement(1185060..1186823) 1 NC_010519.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1186823 6106870 HSM_1027 Haemophilus somnus 2336 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_001784357.1 1185060 R 228400 CDS YP_001784358.1 170717240 6106871 complement(1186889..1187842) 1 NC_010519.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: hso:HS_1148 thioredoxin reductase; thioredoxin reductase 1187842 6106871 HSM_1028 Haemophilus somnus 2336 thioredoxin reductase YP_001784358.1 1186889 R 228400 CDS YP_001784359.1 170717241 6106872 complement(1187971..1188711) 1 NC_010519.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 1188711 pflA 6106872 pflA Haemophilus somnus 2336 pyruvate formate lyase-activating enzyme 1 YP_001784359.1 1187971 R 228400 CDS YP_001784360.1 170717243 6106873 1188976..1189929 1 NC_010519.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 1189929 6106873 HSM_1030 Haemophilus somnus 2336 tagatose 1,6-diphosphate aldolase YP_001784360.1 1188976 D 228400 CDS YP_001784361.1 170717244 6106875 1189943..1191208 1 NC_010519.1 PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; KEGG: hso:HS_1145 tagatose 6-phosphate kinase; tagatose-6-phosphate kinase 1191208 6106875 HSM_1031 Haemophilus somnus 2336 tagatose-6-phosphate kinase YP_001784361.1 1189943 D 228400 CDS YP_001784362.1 170717245 6106876 1191221..1191667 1 NC_010519.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA 1191667 6106876 HSM_1032 Haemophilus somnus 2336 PTS system galactitol-specific transporter subunit IIA YP_001784362.1 1191221 D 228400 CDS YP_001784363.1 170717246 6106877 1191691..1191975 1 NC_010519.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB 1191975 6106877 HSM_1033 Haemophilus somnus 2336 PTS system galactitol-specific transporter subunit IIB YP_001784363.1 1191691 D 228400 CDS YP_001784364.1 170717247 6106878 1191980..1193338 1 NC_010519.1 TIGRFAM: PTS system, galactitol-specific IIC subunit; PFAM: PTS system Galactitol-specific IIC component; KEGG: hso:HS_1142 PTS system, galactitol-specific IIC component; PTS system galactitol-specific transporter subunit IIC 1193338 6106878 HSM_1034 Haemophilus somnus 2336 PTS system galactitol-specific transporter subunit IIC YP_001784364.1 1191980 D 228400 CDS YP_001784365.1 170717248 6106879 1193352..1194395 1 NC_010519.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 1194395 6106879 HSM_1035 Haemophilus somnus 2336 galactitol-1-phosphate dehydrogenase YP_001784365.1 1193352 D 228400 CDS YP_001784366.1 170717249 6106880 1194450..1195280 1 NC_010519.1 PFAM: regulatory protein GntR HTH; regulatory protein DeoR; hypothetical protein; regulatory protein DeoR; KEGG: hso:HS_1140 galactitol utilization operon repressor; DeoR family transcriptional regulator 1195280 6106880 HSM_1036 Haemophilus somnus 2336 DeoR family transcriptional regulator YP_001784366.1 1194450 D 228400 CDS YP_001784367.1 170717250 6106881 complement(1195530..1196246) 1 NC_010519.1 KEGG: hso:HS_1139 hypothetical protein; hypothetical protein 1196246 6106881 HSM_1037 Haemophilus somnus 2336 hypothetical protein YP_001784367.1 1195530 R 228400 CDS YP_001784368.1 170717251 6106882 complement(1196231..1197151) 1 NC_010519.1 PFAM: protein of unknown function DUF692; Xylose isomerase domain protein TIM barrel; KEGG: hso:HS_1138 hypothetical protein; hypothetical protein 1197151 6106882 HSM_1038 Haemophilus somnus 2336 hypothetical protein YP_001784368.1 1196231 R 228400 CDS YP_001784369.1 170717252 6106883 complement(1197197..1197430) 1 NC_010519.1 KEGG: pmu:PM0212 hypothetical HI1601; hypothetical protein 1197430 6106883 HSM_1039 Haemophilus somnus 2336 hypothetical protein YP_001784369.1 1197197 R 228400 CDS YP_001784370.1 170717254 6106884 complement(1197453..1197911) 1 NC_010519.1 PFAM: DoxX family protein; KEGG: hso:HS_1137 hypothetical protein; DoxX family protein 1197911 6106884 HSM_1040 Haemophilus somnus 2336 DoxX family protein YP_001784370.1 1197453 R 228400 CDS YP_001784371.1 170717255 6106886 complement(1198046..1200370) 1 NC_010519.1 TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL; KEGG: hso:HS_1136 formate acetyltransferase; formate acetyltransferase 1200370 6106886 HSM_1041 Haemophilus somnus 2336 formate acetyltransferase YP_001784371.1 1198046 R 228400 CDS YP_001784372.1 170717256 6106887 complement(1200465..1201316) 1 NC_010519.1 PFAM: formate/nitrite transporter; KEGG: hso:HS_1135 formate transporter; formate/nitrite transporter 1201316 6106887 HSM_1042 Haemophilus somnus 2336 formate/nitrite transporter YP_001784372.1 1200465 R 228400 CDS YP_001784373.1 170717257 6106888 1201560..1201910 1 NC_010519.1 PFAM: histidine triad (HIT) protein; KEGG: hso:HS_1134 HIT-like protein; histidine triad (HIT) protein 1201910 6106888 HSM_1043 Haemophilus somnus 2336 histidine triad (HIT) protein YP_001784373.1 1201560 D 228400 CDS YP_001784374.1 170717258 6106889 1201910..1202266 1 NC_010519.1 KEGG: hso:HS_1133 hypothetical protein; hypothetical protein 1202266 6106889 HSM_1044 Haemophilus somnus 2336 hypothetical protein YP_001784374.1 1201910 D 228400 CDS YP_001784375.1 170717259 6106890 1202273..1203319 1 NC_010519.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1203319 6106890 HSM_1045 Haemophilus somnus 2336 beta-hexosaminidase YP_001784375.1 1202273 D 228400 CDS YP_001784376.1 170717260 6106891 1203348..1203866 1 NC_010519.1 PFAM: protein of unknown function DUF1706; KEGG: hso:HS_1131 hypothetical protein; hypothetical protein 1203866 6106891 HSM_1046 Haemophilus somnus 2336 hypothetical protein YP_001784376.1 1203348 D 228400 CDS YP_001784377.1 170717261 6106892 1204077..1204961 1 NC_010519.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 1204961 metF 6106892 metF Haemophilus somnus 2336 5,10-methylenetetrahydrofolate reductase YP_001784377.1 1204077 D 228400 CDS YP_001784378.1 170717262 6106893 complement(1205048..1205512) 1 NC_010519.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1205512 6106893 HSM_1048 Haemophilus somnus 2336 single-stranded DNA-binding protein YP_001784378.1 1205048 R 228400 CDS YP_001784379.1 170717263 6106894 1205691..1208522 1 NC_010519.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrsubunit betas scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1208522 uvrA 6106894 uvrA Haemophilus somnus 2336 excinuclease ABC subunit A YP_001784379.1 1205691 D 228400 CDS YP_001784380.1 170717265 6106895 1208694..1209749 1 NC_010519.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 1209749 6106895 HSM_1050 Haemophilus somnus 2336 rod shape-determining protein MreB YP_001784380.1 1208694 D 228400 CDS YP_001784381.1 170717266 6106897 1209831..1210883 1 NC_010519.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 1210883 6106897 HSM_1051 Haemophilus somnus 2336 rod shape-determining protein MreC YP_001784381.1 1209831 D 228400 CDS YP_001784382.1 170717267 6106898 1210883..1211371 1 NC_010519.1 PFAM: Rod shape-determining protein MreD; KEGG: hso:HS_1125 rod shape-determining protein; rod shape-determining protein MreD 1211371 6106898 HSM_1052 Haemophilus somnus 2336 rod shape-determining protein MreD YP_001784382.1 1210883 D 228400 CDS YP_001784383.1 170717268 6106899 complement(1211397..1212071) 1 NC_010519.1 PFAM: sporulation domain protein; KEGG: hso:HS_1124 cell division protein; sporulation domain-containing protein 1212071 6106899 HSM_1053 Haemophilus somnus 2336 sporulation domain-containing protein YP_001784383.1 1211397 R 228400 CDS YP_001784384.1 170717269 6106900 complement(1212143..1214335) 1 NC_010519.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1214335 6106900 HSM_1054 Haemophilus somnus 2336 primosome assembly protein PriA YP_001784384.1 1212143 R 228400 CDS YP_001784385.1 170717270 6106901 complement(1214340..1215161) 1 NC_010519.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 1215161 mazG 6106901 mazG Haemophilus somnus 2336 nucleoside triphosphate pyrophosphohydrolase YP_001784385.1 1214340 R 228400 CDS YP_001784386.1 170717271 6106902 1215662..1216675 1 NC_010519.1 KEGG: vvu:VV2_0681 hypothetical protein; hypothetical protein 1216675 6106902 HSM_1056 Haemophilus somnus 2336 hypothetical protein YP_001784386.1 1215662 D 228400 CDS YP_001784387.1 170717272 6106903 1216659..1217060 1 NC_010519.1 PFAM: carboxymuconolactone decarboxylase; KEGG: mth:MTH234 gamma-carboxymuconolactone decarboxylase; carboxymuconolactone decarboxylase 1217060 6106903 HSM_1057 Haemophilus somnus 2336 carboxymuconolactone decarboxylase YP_001784387.1 1216659 D 228400 CDS YP_001784388.1 170717273 6106904 1217047..1218279 1 NC_010519.1 PFAM: major facilitator superfamily MFS_1; KEGG: vvu:VV2_0680 permease of the major facilitator superfamily; major facilitator transporter 1218279 6106904 HSM_1058 Haemophilus somnus 2336 major facilitator transporter YP_001784388.1 1217047 D 228400 CDS YP_001784389.1 170717274 6106905 1218624..1219049 1 NC_010519.1 PFAM: UspA domain protein; KEGG: hso:HS_1121 universal stress protein A; UspA domain-containing protein 1219049 6106905 HSM_1059 Haemophilus somnus 2336 UspA domain-containing protein YP_001784389.1 1218624 D 228400 CDS YP_001784390.1 170717275 6106906 1219241..1221865 1 NC_010519.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1221865 alaS 6106906 alaS Haemophilus somnus 2336 alanyl-tRNA synthetase YP_001784390.1 1219241 D 228400 CDS YP_001784391.1 170717276 6106908 1222052..1222234 1 NC_010519.1 PFAM: carbon storage regulator; KEGG: hit:NTHI0977 carbon storage regulator homolog; carbon storage regulator CsrA 1222234 6106908 HSM_1061 Haemophilus somnus 2336 carbon storage regulator CsrA YP_001784391.1 1222052 D 228400 CDS YP_001784392.1 170717277 6106909 1222268..1223632 1 NC_010519.1 PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: hso:HS_1118 phosphomannomutase; phosphomannomutase 1223632 6106909 HSM_1062 Haemophilus somnus 2336 phosphomannomutase YP_001784392.1 1222268 D 228400 CDS YP_001784393.1 170717278 6106910 1223706..1224593 1 NC_010519.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: nucleotidyl transferase; KEGG: hso:HS_1117 UTP--glucose-1-phosphate uridylyltransferase; UTP-glucose-1-phosphate uridylyltransferase 1224593 6106910 HSM_1063 Haemophilus somnus 2336 UTP-glucose-1-phosphate uridylyltransferase YP_001784393.1 1223706 D 228400 CDS YP_001784394.1 170717279 6106911 complement(1224641..1225504) 1 NC_010519.1 TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: hso:HS_1115 DNA adenine methylase; DNA adenine methylase 1225504 6106911 HSM_1064 Haemophilus somnus 2336 DNA adenine methylase YP_001784394.1 1224641 R 228400 CDS YP_001784395.1 170717280 6106912 complement(1225511..1226599) 1 NC_010519.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1226599 aroB 6106912 aroB Haemophilus somnus 2336 3-dehydroquinate synthase YP_001784395.1 1225511 R 228400 CDS YP_001784396.1 170717281 6106913 complement(1226619..1227146) 1 NC_010519.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 1227146 aroK 6106913 aroK Haemophilus somnus 2336 shikimate kinase YP_001784396.1 1226619 R 228400 CDS YP_001784397.1 170717282 6106914 complement(1227328..1228461) 1 NC_010519.1 TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: hso:HS_1112 competence protein E; type IV pilus secretin PilQ 1228461 6106914 HSM_1067 Haemophilus somnus 2336 type IV pilus secretin PilQ YP_001784397.1 1227328 R 228400 CDS YP_001784398.1 170717283 6106915 complement(1228477..1228974) 1 NC_010519.1 KEGG: hso:HS_1111 competence protein C; competence protein C 1228974 6106915 HSM_1068 Haemophilus somnus 2336 competence protein C YP_001784398.1 1228477 R 228400 CDS YP_001784399.1 170717284 6106916 complement(1228978..1229517) 1 NC_010519.1 PFAM: fimbrial assembly family protein; KEGG: hso:HS_1110 competence protein B; fimbrial assembly family protein 1229517 6106916 HSM_1069 Haemophilus somnus 2336 fimbrial assembly family protein YP_001784399.1 1228978 R 228400 CDS YP_001784400.1 170717285 6106917 complement(1229521..1230306) 1 NC_010519.1 KEGG: hso:HS_1109 competence protein A; competence protein A 1230306 6106917 HSM_1070 Haemophilus somnus 2336 competence protein A YP_001784400.1 1229521 R 228400 CDS YP_001784401.1 170717286 6106918 1230431..1232971 1 NC_010519.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: hso:HS_1108 penicillin-binding protein 1A; 1A family penicillin-binding protein 1232971 6106918 HSM_1071 Haemophilus somnus 2336 1A family penicillin-binding protein YP_001784401.1 1230431 D 228400 CDS YP_001784402.1 170717287 6106919 1233031..1233876 1 NC_010519.1 PFAM: protein of unknown function DUF519; KEGG: hso:HS_1107 conserved hypothetical protein; hypothetical protein 1233876 6106919 HSM_1072 Haemophilus somnus 2336 hypothetical protein YP_001784402.1 1233031 D 228400 CDS YP_001784403.1 170717288 6106920 1233966..1235336 1 NC_010519.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 1235336 6106920 HSM_1073 Haemophilus somnus 2336 glutathione reductase YP_001784403.1 1233966 D 228400 CDS YP_001784404.1 170717289 6106921 1235543..1235833 1 NC_010519.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 1235833 hfq 6106921 hfq Haemophilus somnus 2336 RNA-binding protein Hfq YP_001784404.1 1235543 D 228400 CDS YP_001784405.1 170717290 6106922 1235836..1237212 1 NC_010519.1 PFAM: GTP-binding protein HSR1-related; KEGG: hso:HS_1104 GTP-binding protein HflX; GTP-binding protein HSR1-related 1237212 6106922 HSM_1075 Haemophilus somnus 2336 GTP-binding protein HSR1-related YP_001784405.1 1235836 D 228400 CDS YP_001784406.1 170717291 6106923 complement(1237229..1238170) 1 NC_010519.1 PFAM: sigma-54 factor interaction domain-containing protein; KEGG: hso:HS_1103 transcriptional regulatory protein; sigma-54 factor interaction domain-containing protein 1238170 6106923 HSM_1076 Haemophilus somnus 2336 sigma-54 factor interaction domain-containing protein YP_001784406.1 1237229 R 228400 CDS YP_001784407.1 170717292 6106924 1238377..1239771 1 NC_010519.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1239771 fumC 6106924 fumC Haemophilus somnus 2336 fumarate hydratase YP_001784407.1 1238377 D 228400 CDS YP_001784408.1 170717293 6106925 complement(1239854..1240345) 1 NC_010519.1 KEGG: hso:HS_0669 Haemophilus-specific protein, uncharacterized; hypothetical protein 1240345 6106925 HSM_1078 Haemophilus somnus 2336 hypothetical protein YP_001784408.1 1239854 R 228400 CDS YP_001784409.1 170717294 6106926 1240507..1240896 1 NC_010519.1 PFAM: helix-turn-helix domain protein; KEGG: hso:HS_0670 transcriptional regulator; helix-turn-helix domain-containing protein 1240896 6106926 HSM_1079 Haemophilus somnus 2336 helix-turn-helix domain-containing protein YP_001784409.1 1240507 D 228400 CDS YP_001784410.1 170717296 6106927 complement(1241178..1242314) 1 NC_010519.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 1242314 tyrA 6106927 tyrA Haemophilus somnus 2336 bifunctional chorismate mutase/prephenate dehydrogenase YP_001784410.1 1241178 R 228400 CDS YP_001784411.1 170717297 6106929 1242503..1243000 1 NC_010519.1 TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: hso:HS_0672 phosphoribosylaminoimidazole carboxylase (AIR carboxylase); phosphoribosylaminoimidazole carboxylase catalytic subunit 1243000 6106929 HSM_1081 Haemophilus somnus 2336 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_001784411.1 1242503 D 228400 CDS YP_001784412.1 170717298 6106930 complement(1243211..1244020) 1 NC_010519.1 regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 1244020 srlR 6106930 srlR Haemophilus somnus 2336 DNA-binding transcriptional repressor SrlR YP_001784412.1 1243211 R 228400 CDS YP_001784413.1 170717299 6106931 complement(1244063..1244710) 1 NC_010519.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; KEGG: hso:HS_0674 conserved phosphatase; HAD family hydrolase 1244710 6106931 HSM_1083 Haemophilus somnus 2336 HAD family hydrolase YP_001784413.1 1244063 R 228400 CDS YP_001784414.1 170717300 6106932 complement(1244785..1245153) 1 NC_010519.1 regulator for glucitol utilization; DNA-binding transcriptional activator GutM 1245153 6106932 HSM_1084 Haemophilus somnus 2336 DNA-binding transcriptional activator GutM YP_001784414.1 1244785 R 228400 CDS YP_001784415.1 170717301 6106933 complement(1245208..1245996) 1 NC_010519.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 1245996 6106933 HSM_1085 Haemophilus somnus 2336 sorbitol-6-phosphate dehydrogenase YP_001784415.1 1245208 R 228400 CDS YP_001784416.1 170717302 6106934 complement(1246043..1246408) 1 NC_010519.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 1246408 6106934 HSM_1086 Haemophilus somnus 2336 PTS system glucitol/sorbitol-specific transporter subunit IIA YP_001784416.1 1246043 R 228400 CDS YP_001784417.1 170717303 6106935 complement(1246469..1247464) 1 NC_010519.1 TIGRFAM: PTS system, glucitol/sorbitol-specific, IIBC subunit; PFAM: Sorbitol phosphotransferase protein II domain protein; KEGG: hso:HS_0678 PTS system, glucitol/sorbitol-specific IIBC component; PTS system glucitol/sorbitol-specific transporter subunit IIBC 1247464 6106935 HSM_1087 Haemophilus somnus 2336 PTS system glucitol/sorbitol-specific transporter subunit IIBC YP_001784417.1 1246469 R 228400 CDS YP_001784418.1 170717304 6106936 complement(1247501..1248112) 1 NC_010519.1 TIGRFAM: PTS system, glucitol/sorbitol-specific, IIC subunit; PFAM: PTS system protein II sorbitol-specific factor; KEGG: hso:HS_0679 PTS system, glucitol/sorbitol-specific IIC2 component; PTS system glucitol/sorbitol-specific transporter subunit IIC 1248112 6106936 HSM_1088 Haemophilus somnus 2336 PTS system glucitol/sorbitol-specific transporter subunit IIC YP_001784418.1 1247501 R 228400 CDS YP_001784419.1 170717305 6106937 1248725..1250077 1 NC_010519.1 KEGG: fnu:FN0131 hemolysin activator protein precursor; hemolysin activation/secretion protein-like protein 1250077 6106937 HSM_1089 Haemophilus somnus 2336 hemolysin activation/secretion protein-like protein YP_001784419.1 1248725 D 228400 CDS YP_001784420.1 170717307 6106938 1250109..1255376 1 NC_010519.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; PFAM: filamentous haemagglutinin domain protein; KEGG: fnu:FN1817 hemolysin; filamentous hemagglutinin outer membrane protein 1255376 6106938 HSM_1090 Haemophilus somnus 2336 filamentous hemagglutinin outer membrane protein YP_001784420.1 1250109 D 228400 CDS YP_001784421.1 170717308 6106940 complement(1255645..1256820) 1 NC_010519.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: hso:HS_0680 VisC protein, monooxygenase family; UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase 1256820 6106940 HSM_1091 Haemophilus somnus 2336 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase YP_001784421.1 1255645 R 228400 CDS YP_001784422.1 170717309 6106941 complement(1256847..1258046) 1 NC_010519.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; 2-polyprenyl-6-methoxyphenol 4-hydroxylase; PFAM: monooxygenase FAD-binding; KEGG: hso:HS_0681 2-octaprenyl-6-methoxyphenol hydroxylase; 2-polyprenyl-6-methoxyphenol 4-hydroxylase 1258046 6106941 HSM_1092 Haemophilus somnus 2336 2-polyprenyl-6-methoxyphenol 4-hydroxylase YP_001784422.1 1256847 R 228400 CDS YP_001784423.1 170717310 6106942 complement(1258074..1259408) 1 NC_010519.1 PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; KEGG: hso:HS_0682 Xaa-Pro aminopeptidase (proline aminopeptidase P); peptidase M24 1259408 6106942 HSM_1093 Haemophilus somnus 2336 peptidase M24 YP_001784423.1 1258074 R 228400 CDS YP_001784424.1 170717311 6106943 complement(1259564..1260121) 1 NC_010519.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 1260121 6106943 HSM_1094 Haemophilus somnus 2336 hypothetical protein YP_001784424.1 1259564 R 228400 CDS YP_001784425.1 170717312 6106944 1260265..1260564 1 NC_010519.1 PFAM: protein of unknown function DUF710; KEGG: hso:HS_0684 hypothetical protein; hypothetical protein 1260564 6106944 HSM_1095 Haemophilus somnus 2336 hypothetical protein YP_001784425.1 1260265 D 228400 CDS YP_001784426.1 170717313 6106945 1260860..1261426 1 NC_010519.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: hso:HS_0685 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase 1261426 6106945 HSM_1096 Haemophilus somnus 2336 5-formyltetrahydrofolate cyclo-ligase YP_001784426.1 1260860 D 228400 CDS YP_001784427.1 170717314 6106946 complement(1261415..1262077) 1 NC_010519.1 KEGG: hso:HS_0686 AphA-like regulator; AphA-like regulator 1262077 6106946 HSM_1097 Haemophilus somnus 2336 AphA-like regulator YP_001784427.1 1261415 R 228400 CDS YP_001784428.1 170717315 6106947 1262181..1263134 1 NC_010519.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 1263134 serB 6106947 serB Haemophilus somnus 2336 phosphoserine phosphatase YP_001784428.1 1262181 D 228400 CDS YP_001784429.1 170717316 6106948 1263151..1263642 1 NC_010519.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 1263642 6106948 HSM_1099 Haemophilus somnus 2336 nucleotide-binding protein YP_001784429.1 1263151 D 228400 CDS YP_001784430.1 170717319 6106949 complement(1263740..1264492) 1 NC_010519.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: hso:HS_0689 TonB protein; TonB family protein 1264492 6106949 HSM_1100 Haemophilus somnus 2336 TonB family protein YP_001784430.1 1263740 R 228400 CDS YP_001784431.1 170717320 6106952 complement(1264492..1264881) 1 NC_010519.1 TIGRFAM: TonB system transporter ExbD type-2; PFAM: biopolymertransporter ExbD/TolR; KEGG: hso:HS_0690 biopolymer transport protein; TonB system transporter ExbD type-2 1264881 6106952 HSM_1101 Haemophilus somnus 2336 TonB system transporter ExbD type-2 YP_001784431.1 1264492 R 228400 CDS YP_001784432.1 170717321 6106953 complement(1264883..1265338) 1 NC_010519.1 TIGRFAM: TonB-system energizer ExbB type-2; PFAM: MotA/TolQ/ExbB proton channel; KEGG: hso:HS_0691 biopolymer transporter; TonB-system energizer ExbB type-2 1265338 6106953 HSM_1102 Haemophilus somnus 2336 TonB-system energizer ExbB type-2 YP_001784432.1 1264883 R 228400 CDS YP_001784433.1 170717322 6106954 complement(1265732..1267105) 1 NC_010519.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 1267105 6106954 HSM_1103 Haemophilus somnus 2336 argininosuccinate lyase YP_001784433.1 1265732 R 228400 CDS YP_001784434.1 170717323 6106955 1267555..1268421 1 NC_010519.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 1268421 rbn 6106955 rbn Haemophilus somnus 2336 ribonuclease BN YP_001784434.1 1267555 D 228400 CDS YP_001784435.1 170717324 6106956 1268418..1268852 1 NC_010519.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1268852 6106956 HSM_1105 Haemophilus somnus 2336 D-tyrosyl-tRNA(Tyr) deacylase YP_001784435.1 1268418 D 228400 CDS YP_001784436.1 170717325 6106957 complement(1268900..1269778) 1 NC_010519.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 1269778 6106957 HSM_1106 Haemophilus somnus 2336 N-acetylneuraminate lyase YP_001784436.1 1268900 R 228400 CDS YP_001784437.1 170717326 6106958 complement(1269811..1270680) 1 NC_010519.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: hso:HS_0696 RpiR family transcriptional regulator; RpiR family transcriptional regulator 1270680 6106958 HSM_1107 Haemophilus somnus 2336 RpiR family transcriptional regulator YP_001784437.1 1269811 R 228400 CDS YP_001784438.1 170717327 6106959 complement(1270661..1271182) 1 NC_010519.1 PFAM: conserved hypothetical protein 22; KEGG: hso:HS_0697 hypothetical protein; hypothetical protein 1271182 6106959 HSM_1108 Haemophilus somnus 2336 hypothetical protein YP_001784438.1 1270661 R 228400 CDS YP_001784439.1 170717328 6106960 complement(1271198..1272076) 1 NC_010519.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 1272076 6106960 HSM_1109 Haemophilus somnus 2336 N-acetylmannosamine kinase YP_001784439.1 1271198 R 228400 CDS YP_001784440.1 170717330 6106961 complement(1272093..1272785) 1 NC_010519.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1272785 6106961 HSM_1110 Haemophilus somnus 2336 N-acetylmannosamine-6-phosphate 2-epimerase YP_001784440.1 1272093 R 228400 CDS YP_001784441.1 170717331 6106963 complement(1272831..1273421) 1 NC_010519.1 KEGG: hso:HS_0700 N-acylneuraminate cytidylyltransferase; N-acylneuraminate cytidylyltransferase 1273421 6106963 HSM_1111 Haemophilus somnus 2336 N-acylneuraminate cytidylyltransferase YP_001784441.1 1272831 R 228400 CDS YP_001784442.1 170717332 6106964 1273654..1274640 1 NC_010519.1 TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_0701 TRAP dicarboxylate transporter periplasmic component; TRAP dicarboxylate transporter subunit DctP 1274640 6106964 HSM_1112 Haemophilus somnus 2336 TRAP dicarboxylate transporter subunit DctP YP_001784442.1 1273654 D 228400 CDS YP_001784443.1 170717333 6106965 1274695..1276560 1 NC_010519.1 TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: tripartite ATP-independent periplasmic transporter DctQ component; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_0702 TRAP dicarboxylate transporter permease; TRAP dicarboxylate transporter subunit DctM 1276560 6106965 HSM_1113 Haemophilus somnus 2336 TRAP dicarboxylate transporter subunit DctM YP_001784443.1 1274695 D 228400 CDS YP_001784444.1 170717334 6106966 1276911..1279052 1 NC_010519.1 PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; SMART: KH domain protein; KEGG: hso:HS_0703 polynucleotide phosphorylase; polynucleotide phosphorylase/polyadenylase 1279052 6106966 HSM_1114 Haemophilus somnus 2336 polynucleotide phosphorylase/polyadenylase YP_001784444.1 1276911 D 228400 CDS YP_001784445.1 170717335 6106967 1279455..1281260 1 NC_010519.1 PFAM: helicase; DbpA RNA-binding domain protein; DEAD/DEAH box helicase; SMART: DEAD-like helicases; KEGG: hso:HS_0704 ATP-dependent RNA helicase; DEAD/DEAH box helicase 1281260 6106967 HSM_1115 Haemophilus somnus 2336 DEAD/DEAH box helicase YP_001784445.1 1279455 D 228400 CDS YP_001784446.1 170717336 6106968 complement(1281322..1281540) 1 NC_010519.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1281540 infA 6106968 infA Haemophilus somnus 2336 translation initiation factor IF-1 YP_001784446.1 1281322 R 228400 CDS YP_001784447.1 170717337 6106969 1281751..1282422 1 NC_010519.1 PFAM: acylneuraminate cytidylyltransferase; KEGG: hso:HS_0706 CMP-N-acetylneuraminic acid synthetase; N-acylneuraminate cytidylyltransferase 1282422 6106969 HSM_1117 Haemophilus somnus 2336 N-acylneuraminate cytidylyltransferase YP_001784447.1 1281751 D 228400 CDS YP_001784448.1 170717338 6106970 1282529..1283548 1 NC_010519.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: hso:HS_0707 dTDP-D-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase 1283548 6106970 HSM_1118 Haemophilus somnus 2336 dTDP-glucose 4,6-dehydratase YP_001784448.1 1282529 D 228400 CDS YP_001784449.1 170717339 6106971 1283815..1285401 1 NC_010519.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: hso:HS_0708 L-lactate permease; L-lactate transport 1285401 6106971 HSM_1119 Haemophilus somnus 2336 L-lactate transport YP_001784449.1 1283815 D 228400 CDS YP_001784450.1 170717341 6106972 1285481..1286212 1 NC_010519.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: hso:HS_0709 hypothetical protein; hypothetical protein 1286212 6106972 HSM_1120 Haemophilus somnus 2336 hypothetical protein YP_001784450.1 1285481 D 228400 CDS YP_001784451.1 170717342 6106974 1286214..1287626 1 NC_010519.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF162; KEGG: hso:HS_0710 hypothetical protein; iron-sulfur cluster binding protein 1287626 6106974 HSM_1121 Haemophilus somnus 2336 iron-sulfur cluster binding protein YP_001784451.1 1286214 D 228400 CDS YP_001784452.1 170717343 6106975 1287626..1288324 1 NC_010519.1 PFAM: protein of unknown function DUF162; KEGG: hso:HS_0711 conserved hypothetical protein; hypothetical protein 1288324 6106975 HSM_1122 Haemophilus somnus 2336 hypothetical protein YP_001784452.1 1287626 D 228400 CDS YP_001784453.1 170717344 6106976 complement(1288397..1290109) 1 NC_010519.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 1290109 dipZ 6106976 dipZ Haemophilus somnus 2336 thiol:disulfide interchange protein YP_001784453.1 1288397 R 228400 CDS YP_001784454.1 170717345 6106977 1290317..1291033 1 NC_010519.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: hso:HS_0713 aerobic respiration control protein; two-component response regulator 1291033 6106977 HSM_1124 Haemophilus somnus 2336 two-component response regulator YP_001784454.1 1290317 D 228400 CDS YP_001784455.1 170717346 6106978 complement(1291212..1292192) 1 NC_010519.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1292192 6106978 HSM_1125 Haemophilus somnus 2336 23S rRNA pseudouridylate synthase C YP_001784455.1 1291212 R 228400 CDS YP_001784456.1 170717347 6106979 1292611..1295439 1 NC_010519.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: hso:HS_0715 ribonuclease E; ribonuclease 1295439 6106979 HSM_1126 Haemophilus somnus 2336 ribonuclease YP_001784456.1 1292611 D 228400 CDS YP_001784457.1 170717348 6108886 complement(1295897..1298752) 1 NC_010519.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 1298752 6108886 HSM_1127 Haemophilus somnus 2336 DNA polymerase I YP_001784457.1 1295897 R 228400 CDS YP_001784458.1 170717349 6106981 1298960..1300972 1 NC_010519.1 TIGRFAM: ATP-dependent DNA helicase Rep; PFAM: UvrD/REP helicase; KEGG: hso:HS_0719 ATP-dependent DNA helicase; ATP-dependent DNA helicase Rep 1300972 6106981 HSM_1128 Haemophilus somnus 2336 ATP-dependent DNA helicase Rep YP_001784458.1 1298960 D 228400 CDS YP_001784459.1 170717350 6108889 1301649..1302638 1 NC_010519.1 PFAM: phage integrase family protein; KEGG: hso:HS_1220 integrase; phage integrase family protein 1302638 6108889 HSM_1129 Haemophilus somnus 2336 phage integrase family protein YP_001784459.1 1301649 D 228400 CDS YP_001784460.1 170717352 6106983 complement(1302635..1302931) 1 NC_010519.1 KEGG: hso:HS_1219 Haemophilus-specific protein, uncharacterized; hypothetical protein 1302931 6106983 HSM_1130 Haemophilus somnus 2336 hypothetical protein YP_001784460.1 1302635 R 228400 CDS YP_001784461.1 170717353 6106985 complement(1302900..1305263) 1 NC_010519.1 PFAM: bacteriophage replication gene A; KEGG: spt:SPA2623 phage gene; bacteriophage replication gene A 1305263 6106985 HSM_1131 Haemophilus somnus 2336 bacteriophage replication gene A YP_001784461.1 1302900 R 228400 CDS YP_001784462.1 170717354 6106986 complement(1305282..1305575) 1 NC_010519.1 hypothetical protein 1305575 6106986 HSM_1132 Haemophilus somnus 2336 hypothetical protein YP_001784462.1 1305282 R 228400 CDS YP_001784463.1 170717355 6106987 complement(1305572..1305925) 1 NC_010519.1 hypothetical protein 1305925 6106987 HSM_1133 Haemophilus somnus 2336 hypothetical protein YP_001784463.1 1305572 R 228400 CDS YP_001784464.1 170717356 6106988 complement(1305941..1306231) 1 NC_010519.1 hypothetical protein 1306231 6106988 HSM_1134 Haemophilus somnus 2336 hypothetical protein YP_001784464.1 1305941 R 228400 CDS YP_001784465.1 170717357 6106989 complement(1306630..1306875) 1 NC_010519.1 KEGG: ecp:ECP_1147 hypothetical protein; hypothetical protein 1306875 6106989 HSM_1135 Haemophilus somnus 2336 hypothetical protein YP_001784465.1 1306630 R 228400 CDS YP_001784466.1 170717358 6106990 1307015..1307704 1 NC_010519.1 PFAM: helix-turn-helix domain protein; peptidase S24 S26A and S26B; bacteriophage CI repressor; KEGG: spt:SPA2414 transcriptional activator-regulatory protein; phage repressor 1307704 6106990 HSM_1136 Haemophilus somnus 2336 phage repressor YP_001784466.1 1307015 D 228400 CDS YP_001784467.1 170717359 6106991 complement(1307987..1309162) 1 NC_010519.1 PFAM: phage late control D family protein; KEGG: stt:t3444 regulator of late gene expression; phage late control D family protein 1309162 6106991 HSM_1137 Haemophilus somnus 2336 phage late control D family protein YP_001784467.1 1307987 R 228400 CDS YP_001784468.1 170717360 6106992 complement(1309159..1309602) 1 NC_010519.1 PFAM: phage P2 GpU family protein; KEGG: sgl:SG1860 phage tail protein; phage P2 GpU family protein 1309602 6106992 HSM_1138 Haemophilus somnus 2336 phage P2 GpU family protein YP_001784468.1 1309159 R 228400 CDS YP_001784469.1 170717361 6106993 complement(1309807..1310115) 1 NC_010519.1 PFAM: phage tail E family protein; KEGG: rsp:RSP_3353 phage related tail protein; phage tail E family protein 1310115 6106993 HSM_1139 Haemophilus somnus 2336 phage tail E family protein YP_001784469.1 1309807 R 228400 CDS YP_001784470.1 170717363 6106994 complement(1310143..1310652) 1 NC_010519.1 PFAM: phage major tail tube protein; KEGG: xcc:XCC2989 phage-related tail protein; phage major tail tube protein 1310652 6106994 HSM_1140 Haemophilus somnus 2336 phage major tail tube protein YP_001784470.1 1310143 R 228400 CDS YP_001784471.1 170717364 6106996 complement(1310663..1311916) 1 NC_010519.1 PFAM: phage tail sheath protein; KEGG: yps:YPTB1841 bacteriophage P2 tail sheath protein; phage tail sheath protein 1311916 6106996 HSM_1141 Haemophilus somnus 2336 phage tail sheath protein YP_001784471.1 1310663 R 228400 CDS YP_001784472.1 170717365 6106997 1312129..1312377 1 NC_010519.1 PFAM: protein of unknown function DUF172; KEGG: aeh:Mlg_1787 prevent-host-death family protein; hypothetical protein 1312377 6106997 HSM_1142 Haemophilus somnus 2336 hypothetical protein YP_001784472.1 1312129 D 228400 CDS YP_001784473.1 170717366 6106998 1312377..1312640 1 NC_010519.1 TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin Txe/YoeB; KEGG: aeh:Mlg_1786 addiction module toxin, Txe/YoeB family; addiction module antitoxin 1312640 6106998 HSM_1143 Haemophilus somnus 2336 addiction module antitoxin YP_001784473.1 1312377 D 228400 CDS YP_001784474.1 170717367 6106999 1312855..1313043 1 NC_010519.1 hypothetical protein 1313043 6106999 HSM_1144 Haemophilus somnus 2336 hypothetical protein YP_001784474.1 1312855 D 228400 CDS YP_001784475.1 170717368 6107000 complement(1313046..1313522) 1 NC_010519.1 KEGG: msu:MS0077 hypothetical protein; hypothetical protein 1313522 6107000 HSM_1145 Haemophilus somnus 2336 hypothetical protein YP_001784475.1 1313046 R 228400 CDS YP_001784476.1 170717369 6107001 complement(1313515..1314141) 1 NC_010519.1 KEGG: nme:NMB1119 hypothetical protein; hypothetical protein 1314141 6107001 HSM_1146 Haemophilus somnus 2336 hypothetical protein YP_001784476.1 1313515 R 228400 CDS YP_001784477.1 170717370 6107002 1314204..1314455 1 NC_010519.1 KEGG: tde:TDE1648 hypothetical protein; hypothetical protein 1314455 6107002 HSM_1147 Haemophilus somnus 2336 hypothetical protein YP_001784477.1 1314204 D 228400 CDS YP_001784478.1 170717371 6107003 1314439..1314756 1 NC_010519.1 KEGG: xfa:XF0534 hypothetical protein; hypothetical protein 1314756 6107003 HSM_1148 Haemophilus somnus 2336 hypothetical protein YP_001784478.1 1314439 D 228400 CDS YP_001784479.1 170717372 6107004 complement(1314792..1316891) 1 NC_010519.1 PFAM: phage tail fiber repeat 2 protein; phage Tail Collar domain protein; KEGG: nme:NMB1115 tail fibre protein; phage tail collar domain-containing protein 1316891 6107004 HSM_1149 Haemophilus somnus 2336 phage tail collar domain-containing protein YP_001784479.1 1314792 R 228400 CDS YP_001784480.1 170717374 6107005 complement(1316937..1317491) 1 NC_010519.1 TIGRFAM: phage tail protein I; KEGG: hit:NTHI1858 predicted bacteriophage P2-related tail formation protein gpI; phage tail protein I 1317491 6107005 HSM_1150 Haemophilus somnus 2336 phage tail protein I YP_001784480.1 1316937 R 228400 CDS YP_001784481.1 170717375 6107007 complement(1317481..1318395) 1 NC_010519.1 PFAM: Baseplate J family protein; KEGG: hit:NTHI1860 predicted phage-related baseplate assembly protein; baseplate J family protein 1318395 6107007 HSM_1151 Haemophilus somnus 2336 baseplate J family protein YP_001784481.1 1317481 R 228400 CDS YP_001784482.1 170717376 6107008 complement(1318379..1318735) 1 NC_010519.1 PFAM: GPW/gp25 family protein; KEGG: hit:NTHI1861 predicted baseplate assembly protein W; GPW/gp25 family protein 1318735 6107008 HSM_1152 Haemophilus somnus 2336 GPW/gp25 family protein YP_001784482.1 1318379 R 228400 CDS YP_001784483.1 170717377 6107009 complement(1318735..1319361) 1 NC_010519.1 PFAM: phage baseplate assembly protein V; KEGG: hit:NTHI1862 predicted phage P2-like baseplate assembly protein; phage baseplate assembly protein V 1319361 6107009 HSM_1153 Haemophilus somnus 2336 phage baseplate assembly protein V YP_001784483.1 1318735 R 228400 CDS YP_001784484.1 170717378 6107010 complement(1319575..1319922) 1 NC_010519.1 hypothetical protein 1319922 6107010 HSM_1154 Haemophilus somnus 2336 hypothetical protein YP_001784484.1 1319575 R 228400 CDS YP_001784485.1 170717379 6107011 complement(1319910..1320194) 1 NC_010519.1 KEGG: plu:plu2305 hypothetical protein; hypothetical protein 1320194 6107011 HSM_1155 Haemophilus somnus 2336 hypothetical protein YP_001784485.1 1319910 R 228400 CDS YP_001784486.1 170717380 6107012 complement(1320349..1322847) 1 NC_010519.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: csa:Csal_1375 phage tail tape measure protein TP901, core region; TP901 family phage tail tape measure protein 1322847 6107012 HSM_1156 Haemophilus somnus 2336 TP901 family phage tail tape measure protein YP_001784486.1 1320349 R 228400 CDS YP_001784487.1 170717381 6107013 complement(1323613..1324074) 1 NC_010519.1 TIGRFAM: phage virion morphogenesis protein; PFAM: phage virion morphogenesis ( tail completion) protein; KEGG: hit:NTHI1873 probable bacteriophage tail completion protein gpS homolog; phage virion morphogenesis protein 1324074 6107013 HSM_1157 Haemophilus somnus 2336 phage virion morphogenesis protein YP_001784487.1 1323613 R 228400 CDS YP_001784488.1 170717382 6107014 complement(1324087..1324527) 1 NC_010519.1 PFAM: P2 phage tail completion R family protein; KEGG: yps:YPTB1850 gpR [Enterobacteria phage P2]; P2 phage tail completion R family protein 1324527 6107014 HSM_1158 Haemophilus somnus 2336 P2 phage tail completion R family protein YP_001784488.1 1324087 R 228400 CDS YP_001784489.1 170717383 6107015 complement(1324885..1325343) 1 NC_010519.1 hypothetical protein 1325343 6107015 HSM_1159 Haemophilus somnus 2336 hypothetical protein YP_001784489.1 1324885 R 228400 CDS YP_001784490.1 170717385 6107016 complement(1325327..1325863) 1 NC_010519.1 PFAM: glycoside hydrolase family 24; KEGG: hso:HS_1388 lysozyme, phage-related lysozyme; glycoside hydrolase family protein 1325863 6107016 HSM_1160 Haemophilus somnus 2336 glycoside hydrolase family protein YP_001784490.1 1325327 R 228400 CDS YP_001784491.1 170717386 6107018 complement(1325856..1326080) 1 NC_010519.1 KEGG: hit:NTHI1881 hypothetical protein; hypothetical protein 1326080 6107018 HSM_1161 Haemophilus somnus 2336 hypothetical protein YP_001784491.1 1325856 R 228400 CDS YP_001784492.1 170717387 6107019 complement(1326081..1326296) 1 NC_010519.1 PFAM: phage tail X family protein; KEGG: hit:NTHI1882 hypothetical protein; phage tail X family protein 1326296 6107019 HSM_1162 Haemophilus somnus 2336 phage tail X family protein YP_001784492.1 1326081 R 228400 CDS YP_001784493.1 170717388 6107020 complement(1326296..1326808) 1 NC_010519.1 PFAM: phage head completion; KEGG: hit:NTHI1883 hypothetical protein; phage head completion 1326808 6107020 HSM_1163 Haemophilus somnus 2336 phage head completion YP_001784493.1 1326296 R 228400 CDS YP_001784494.1 170717389 6107021 complement(1326912..1327565) 1 NC_010519.1 PFAM: phage small terminase subunit; KEGG: hit:NTHI1884 predicted terminase, endonuclease subunit; phage small terminase subunit 1327565 6107021 HSM_1164 Haemophilus somnus 2336 phage small terminase subunit YP_001784494.1 1326912 R 228400 CDS YP_001784495.1 170717390 6107022 complement(1327577..1328629) 1 NC_010519.1 TIGRFAM: phage major capsid protein, P2 family; PFAM: phage major capsid protein P2; KEGG: hit:NTHI1885 predicted major capsid protein; P2 family phage major capsid protein 1328629 6107022 HSM_1165 Haemophilus somnus 2336 P2 family phage major capsid protein YP_001784495.1 1327577 R 228400 CDS YP_001784496.1 170717391 6107023 complement(1328653..1329477) 1 NC_010519.1 PFAM: phage capsid scaffolding; KEGG: hit:NTHI1887 predicted capsid scaffolding protein; phage capsid scaffolding 1329477 6107023 HSM_1166 Haemophilus somnus 2336 phage capsid scaffolding YP_001784496.1 1328653 R 228400 CDS YP_001784497.1 170717392 6107024 1329641..1329985 1 NC_010519.1 PFAM: terminase ATPase; KEGG: hit:NTHI1888 terminase, ATPase; terminase ATPase 1329985 6107024 HSM_1167 Haemophilus somnus 2336 terminase ATPase YP_001784497.1 1329641 D 228400 CDS YP_001784498.1 170717393 6107025 complement(1330234..1333344) 1 NC_010519.1 TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; PFAM: TonB-dependent receptor; KEGG: hit:NTHI0782 hemoglobin-haptoglobin binding protein B; TonB-dependent hemoglobin/transferrin/lactoferrin family receptor 1333344 6107025 HSM_1168 Haemophilus somnus 2336 TonB-dependent hemoglobin/transferrin/lactoferrin family receptor YP_001784498.1 1330234 R 228400 CDS YP_001784499.1 170717394 6107026 complement(1333587..1334108) 1 NC_010519.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: hso:HS_0722 heme binding protein; pyridoxamine 5'-phosphate oxidase-like FMN-binding protein 1334108 6107026 HSM_1169 Haemophilus somnus 2336 pyridoxamine 5'-phosphate oxidase-like FMN-binding protein YP_001784499.1 1333587 R 228400 CDS YP_001784500.1 170717396 6107027 complement(1334126..1334620) 1 NC_010519.1 PFAM: protein of unknown function DUF1008; KEGG: hso:HS_0723 HugX protein; hypothetical protein 1334620 6107027 HSM_1170 Haemophilus somnus 2336 hypothetical protein YP_001784500.1 1334126 R 228400 CDS YP_001784501.1 170717397 6107029 1334823..1335452 1 NC_010519.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 1335452 rrmJ 6107029 rrmJ Haemophilus somnus 2336 23S rRNA methyltransferase J YP_001784501.1 1334823 D 228400 CDS YP_001784502.1 170717398 6107030 1335583..1337412 1 NC_010519.1 KEGG: hso:HS_0725 cell division protein; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; ATPase AAA central domain protein; peptidase M41 FtsH extracellular; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; ATP-dependent metalloprotease FtsH 1337412 6107030 HSM_1172 Haemophilus somnus 2336 ATP-dependent metalloprotease FtsH YP_001784502.1 1335583 D 228400 CDS YP_001784503.1 170717399 6107031 1337745..1338542 1 NC_010519.1 PFAM: LicD family protein; KEGG: hso:HS_0727 lipopolysaccharide cholinephosphotransferase; LicD family protein 1338542 6107031 HSM_1173 Haemophilus somnus 2336 LicD family protein YP_001784503.1 1337745 D 228400 CDS YP_001784504.1 170717400 6107033 complement(1339853..1340113) 1 NC_010519.1 KEGG: hso:HS_0728 hemin receptor, outer membrane protein; hemin receptor, outer membrane protein 1340113 6107033 HSM_1176 Haemophilus somnus 2336 hemin receptor, outer membrane protein YP_001784504.1 1339853 R 228400 CDS YP_001784505.1 170717401 6107034 1340138..1340428 1 NC_010519.1 KEGG: spd:SPD_0914 23S rRNA (uracil-5-)-methyltransferase RumA; 23S rRNA (uracil-5-)-methyltransferase RumA 1340428 6107034 HSM_1177 Haemophilus somnus 2336 23S rRNA (uracil-5-)-methyltransferase RumA YP_001784505.1 1340138 D 228400 CDS YP_001784506.1 170717402 6107035 1340805..1341248 1 NC_010519.1 KEGG: sha:SH2379 hypothetical protein; hypothetical protein 1341248 6107035 HSM_1178 Haemophilus somnus 2336 hypothetical protein YP_001784506.1 1340805 D 228400 CDS YP_001784507.1 170717404 6107037 1342054..1342632 1 NC_010519.1 KEGG: sav:SAV0404 hypothetical protein; hypothetical protein 1342632 6107037 HSM_1181 Haemophilus somnus 2336 hypothetical protein YP_001784507.1 1342054 D 228400 CDS YP_001784508.1 170717405 6107039 1342706..1343545 1 NC_010519.1 KEGG: dar:Daro_1916 nucleotide-binding protein containing TIR-like domain; nucleic acid-binding protein 1343545 6107039 HSM_1182 Haemophilus somnus 2336 nucleic acid-binding protein YP_001784508.1 1342706 D 228400 CDS YP_001784509.1 170717406 6107040 1343736..1344005 1 NC_010519.1 KEGG: spi:MGAS10750_Spy1685 hypothetical protein; hypothetical protein 1344005 6107040 HSM_1183 Haemophilus somnus 2336 hypothetical protein YP_001784509.1 1343736 D 228400 CDS YP_001784510.1 170717407 6107041 complement(1343931..1344473) 1 NC_010519.1 KEGG: spi:MGAS10750_Spy1699 hypothetical protein; hypothetical protein 1344473 6107041 HSM_1184 Haemophilus somnus 2336 hypothetical protein YP_001784510.1 1343931 R 228400 CDS YP_001784511.1 170717408 6107042 1344682..1344798 1 NC_010519.1 hypothetical protein 1344798 6107042 HSM_1185 Haemophilus somnus 2336 hypothetical protein YP_001784511.1 1344682 D 228400 CDS YP_001784512.1 170717409 6107043 1344940..1345881 1 NC_010519.1 hypothetical protein 1345881 6107043 HSM_1186 Haemophilus somnus 2336 hypothetical protein YP_001784512.1 1344940 D 228400 CDS YP_001784513.1 170717410 6107044 1346067..1346642 1 NC_010519.1 KEGG: neu:NE2094 hypothetical protein; hypothetical protein 1346642 6107044 HSM_1187 Haemophilus somnus 2336 hypothetical protein YP_001784513.1 1346067 D 228400 CDS YP_001784514.1 170717411 6107045 1346768..1347130 1 NC_010519.1 hypothetical protein 1347130 6107045 HSM_1188 Haemophilus somnus 2336 hypothetical protein YP_001784514.1 1346768 D 228400 CDS YP_001784515.1 170717412 6107046 1347140..1348855 1 NC_010519.1 PFAM: protein of unknown function DUF87; KEGG: neu:NE2095 hypothetical protein; hypothetical protein 1348855 6107046 HSM_1189 Haemophilus somnus 2336 hypothetical protein YP_001784515.1 1347140 D 228400 CDS YP_001784516.1 170717414 6107047 complement(1349004..1349972) 1 NC_010519.1 PFAM: Relaxase/mobilization nuclease family protein; KEGG: spi:MGAS10750_Spy1708 relaxase; relaxase/mobilization nuclease family protein 1349972 6107047 HSM_1190 Haemophilus somnus 2336 relaxase/mobilization nuclease family protein YP_001784516.1 1349004 R 228400 CDS YP_001784517.1 170717415 6107049 1350057..1350629 1 NC_010519.1 PFAM: regulatory protein TetR; KEGG: tde:TDE0246 TetR family transcriptional regulator; TetR family transcriptional regulator 1350629 6107049 HSM_1191 Haemophilus somnus 2336 TetR family transcriptional regulator YP_001784517.1 1350057 D 228400 CDS YP_001784518.1 170717416 6107050 1350716..1351171 1 NC_010519.1 KEGG: tde:TDE0245 ABC transporter permease/ATP-binding protein protein; ABC transporter permease/ATP-binding protein 1351171 6107050 HSM_1192 Haemophilus somnus 2336 ABC transporter permease/ATP-binding protein YP_001784518.1 1350716 D 228400 CDS YP_001784519.1 170717417 6107051 1351225..1351563 1 NC_010519.1 KEGG: tde:TDE0244 ABC transporter permease/ATP-binding protein protein; cobalt ABC transporter ATPase 1351563 6107051 HSM_1193 Haemophilus somnus 2336 cobalt ABC transporter ATPase YP_001784519.1 1351225 D 228400 CDS YP_001784520.1 170717418 6107053 1352387..1353214 1 NC_010519.1 TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; KEGG: hso:HS_0729 dihydropteroate synthase; dihydropteroate synthase 1353214 6107053 HSM_1196 Haemophilus somnus 2336 dihydropteroate synthase YP_001784520.1 1352387 D 228400 CDS YP_001784521.1 170717419 6107054 1353305..1354639 1 NC_010519.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1354639 glmM 6107054 glmM Haemophilus somnus 2336 phosphoglucosamine mutase YP_001784521.1 1353305 D 228400 CDS YP_001784522.1 170717420 6107055 1354653..1355120 1 NC_010519.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: phosphoglycerate mutase; KEGG: hso:HS_0731 phosphohistidine phosphatase; phosphohistidine phosphatase SixA 1355120 6107055 HSM_1198 Haemophilus somnus 2336 phosphohistidine phosphatase SixA YP_001784522.1 1354653 D 228400 CDS YP_001784523.1 170717421 6107056 1355125..1356084 1 NC_010519.1 PFAM: Auxin Efflux Carrier; KEGG: hso:HS_0732 conserved hypothetical protein; hypothetical protein 1356084 6107056 HSM_1199 Haemophilus somnus 2336 hypothetical protein YP_001784523.1 1355125 D 228400 CDS YP_001784524.1 170717424 6107057 1356212..1358134 1 NC_010519.1 SMART: helicase c2; KEGG: hso:HS_0733 ATP-dependent DNA helicase; helicase c2 1358134 6107057 HSM_1200 Haemophilus somnus 2336 helicase c2 YP_001784524.1 1356212 D 228400 CDS YP_001784525.1 170717425 6107060 1358139..1358855 1 NC_010519.1 PFAM: peptidase M22 glycoprotease; KEGG: hso:HS_0734 glycoprotease family protein; peptidase M22 glycoprotease 1358855 6107060 HSM_1201 Haemophilus somnus 2336 peptidase M22 glycoprotease YP_001784525.1 1358139 D 228400 CDS YP_001784526.1 170717426 6107061 1359081..1360763 1 NC_010519.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1360763 6107061 HSM_1202 Haemophilus somnus 2336 long-chain-fatty-acid--CoA ligase YP_001784526.1 1359081 D 228400 CDS YP_001784527.1 170717427 6107062 1360869..1362014 1 NC_010519.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: hso:HS_0736 ribonuclease D; ribonuclease D 1362014 6107062 HSM_1203 Haemophilus somnus 2336 ribonuclease D YP_001784527.1 1360869 D 228400 CDS YP_001784528.1 170717428 6107063 complement(1362132..1362719) 1 NC_010519.1 PFAM: transport-associated; SMART: transport-associated and nodulation region; KEGG: hso:HS_0737 hemolysin; hypothetical protein 1362719 6107063 HSM_1204 Haemophilus somnus 2336 hypothetical protein YP_001784528.1 1362132 R 228400 CDS YP_001784529.1 170717429 6107064 complement(1362781..1363365) 1 NC_010519.1 KEGG: hso:HS_0738 conserved hypothetical protein; hypothetical protein 1363365 6107064 HSM_1205 Haemophilus somnus 2336 hypothetical protein YP_001784529.1 1362781 R 228400 CDS YP_001784530.1 170717430 6107065 complement(1363371..1363733) 1 NC_010519.1 PFAM: protein of unknown function UPF0102; KEGG: hso:HS_0739 conserved hypothetical protein; hypothetical protein 1363733 6107065 HSM_1206 Haemophilus somnus 2336 hypothetical protein YP_001784530.1 1363371 R 228400 CDS YP_001784531.1 170717431 6107066 complement(1363730..1365490) 1 NC_010519.1 PFAM: LppC family lipoprotein; KEGG: hso:HS_0740 LppC precursor; LppC family lipoprotein 1365490 6107066 HSM_1207 Haemophilus somnus 2336 LppC family lipoprotein YP_001784531.1 1363730 R 228400 CDS YP_001784532.1 170717432 6107067 1365576..1366421 1 NC_010519.1 PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: hso:HS_0741 conserved hypothetical protein; uroporphyrin-III C/tetrapyrrole methyltransferase 1366421 6107067 HSM_1208 Haemophilus somnus 2336 uroporphyrin-III C/tetrapyrrole methyltransferase YP_001784532.1 1365576 D 228400 CDS YP_001784533.1 170717433 6107068 1366498..1367121 1 NC_010519.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: hso:HS_0742 conserved hypothetical protein; Sua5/YciO/YrdC/YwlC family protein 1367121 6107068 HSM_1209 Haemophilus somnus 2336 Sua5/YciO/YrdC/YwlC family protein YP_001784533.1 1366498 D 228400 CDS YP_001784534.1 170717435 6107069 1367182..1368228 1 NC_010519.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: hso:HS_0743 ribosomal large subunit pseudouridine synthase B; pseudouridine synthase 1368228 6107069 HSM_1210 Haemophilus somnus 2336 pseudouridine synthase YP_001784534.1 1367182 D 228400 CDS YP_001784535.1 170717436 6107071 1368276..1368929 1 NC_010519.1 KEGG: hso:HS_1709 transposase; transposase 1368929 6107071 HSM_1211 Haemophilus somnus 2336 transposase YP_001784535.1 1368276 D 228400 CDS YP_001784536.1 170717437 6107072 complement(1369169..1370338) 1 NC_010519.1 PFAM: Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0602 adhesin; hemagluttinin domain-containing protein 1370338 6107072 HSM_1212 Haemophilus somnus 2336 hemagluttinin domain-containing protein YP_001784536.1 1369169 R 228400 CDS YP_001784537.1 170717438 6107073 complement(1370817..1372202) 1 NC_010519.1 PFAM: outer membrane efflux protein; KEGG: hso:HS_0746 outer membrane protein; outer membrane efflux protein 1372202 6107073 HSM_1213 Haemophilus somnus 2336 outer membrane efflux protein YP_001784537.1 1370817 R 228400 CDS YP_001784538.1 170717439 6107074 complement(1372333..1373064) 1 NC_010519.1 PFAM: regulatory protein DeoR; regulatory protein DeoR; KEGG: hso:HS_0747 deoxyribose operon repressor; DeoR family transcriptional regulator 1373064 6107074 HSM_1214 Haemophilus somnus 2336 DeoR family transcriptional regulator YP_001784538.1 1372333 R 228400 CDS YP_001784539.1 170717440 6107075 complement(1373089..1373763) 1 NC_010519.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 1373763 6107075 HSM_1215 Haemophilus somnus 2336 deoxyribose-phosphate aldolase YP_001784539.1 1373089 R 228400 CDS YP_001784540.1 170717441 6107076 1373933..1374853 1 NC_010519.1 TIGRFAM: ribokinase; PFAM: PfkB domain protein; KEGG: hso:HS_0749 ribokinase; ribokinase 1374853 6107076 HSM_1216 Haemophilus somnus 2336 ribokinase YP_001784540.1 1373933 D 228400 CDS YP_001784541.1 170717442 6107077 1374864..1376156 1 NC_010519.1 TIGRFAM: L-fucose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_0750 fucose permease; L-fucose transporter 1376156 6107077 HSM_1217 Haemophilus somnus 2336 L-fucose transporter YP_001784541.1 1374864 D 228400 CDS YP_001784542.1 170717443 6107078 1376158..1377171 1 NC_010519.1 KEGG: hso:HS_0751 hypothetical protein; hypothetical protein 1377171 6107078 HSM_1218 Haemophilus somnus 2336 hypothetical protein YP_001784542.1 1376158 D 228400 CDS YP_001784543.1 170717444 6107079 1377440..1377868 1 NC_010519.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1377868 rplM 6107079 rplM Haemophilus somnus 2336 50S ribosomal protein L13 YP_001784543.1 1377440 D 228400 CDS YP_001784544.1 170717446 6107080 1377885..1378277 1 NC_010519.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1378277 rpsI 6107080 rpsI Haemophilus somnus 2336 30S ribosomal protein S9 YP_001784544.1 1377885 D 228400 CDS YP_001784545.1 170717447 6107082 1378422..1379060 1 NC_010519.1 PFAM: glutathione S-transferase domain; KEGG: hso:HS_0754 stringent starvation protein A; glutathione S-transferase 1379060 6107082 HSM_1221 Haemophilus somnus 2336 glutathione S-transferase YP_001784545.1 1378422 D 228400 CDS YP_001784546.1 170717448 6107083 1379068..1379523 1 NC_010519.1 PFAM: stringent starvation protein B; KEGG: hso:HS_0755 stringent starvation protein B; ClpXP protease specificity-enhancing factor 1379523 6107083 HSM_1222 Haemophilus somnus 2336 ClpXP protease specificity-enhancing factor YP_001784546.1 1379068 D 228400 CDS YP_001784547.1 170717449 6107084 complement(1379596..1380999) 1 NC_010519.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1380999 asnC 6107084 asnC Haemophilus somnus 2336 asparaginyl-tRNA synthetase YP_001784547.1 1379596 R 228400 CDS YP_001784548.1 170717450 6107085 1381202..1382419 1 NC_010519.1 KEGG: hso:HS_0757 NagC-like transcriptional regulator; NagC-like transcriptional regulator 1382419 6107085 HSM_1224 Haemophilus somnus 2336 NagC-like transcriptional regulator YP_001784548.1 1381202 D 228400 CDS YP_001784549.1 170717451 6107086 complement(1382555..1383343) 1 NC_010519.1 PFAM: regulatory protein IclR; IclR family transcripitonal regulator; KEGG: hso:HS_0758 transcriptional regulator, IclR family; IclR family transcripitonal regulator 1383343 6107086 HSM_1225 Haemophilus somnus 2336 IclR family transcripitonal regulator YP_001784549.1 1382555 R 228400 CDS YP_001784550.1 170717452 6107087 1383566..1384564 1 NC_010519.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 1384564 6107087 HSM_1226 Haemophilus somnus 2336 2,3-diketo-L-gulonate reductase YP_001784550.1 1383566 D 228400 CDS YP_001784551.1 170717453 6107088 1384669..1385151 1 NC_010519.1 PFAM: tripartite ATP-independent periplasmic transporter DctQ component; KEGG: hso:HS_0760 tripartite ATP-independent periplasmic transporters, DctQ component; tripartite ATP-independent periplasmic transporter DctQ 1385151 6107088 HSM_1227 Haemophilus somnus 2336 tripartite ATP-independent periplasmic transporter DctQ YP_001784551.1 1384669 D 228400 CDS YP_001784552.1 170717454 6107089 1385148..1386428 1 NC_010519.1 TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: citrate transporter; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_0761 integral membrane protein, DedA family; TRAP dicarboxylate transporter subunit DctM 1386428 6107089 HSM_1228 Haemophilus somnus 2336 TRAP dicarboxylate transporter subunit DctM YP_001784552.1 1385148 D 228400 CDS YP_001784553.1 170717455 6107090 1386448..1387434 1 NC_010519.1 TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_0762 C4-dicarboxylate transporter, periplasmic component; TRAP dicarboxylate transporter subunit DctP 1387434 6107090 HSM_1229 Haemophilus somnus 2336 TRAP dicarboxylate transporter subunit DctP YP_001784553.1 1386448 D 228400 CDS YP_001784554.1 170717457 6107091 1387514..1389031 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0763 ribose ABC transporter ATP-binding protein; ABC transporter 1389031 6107091 HSM_1230 Haemophilus somnus 2336 ABC transporter YP_001784554.1 1387514 D 228400 CDS YP_001784555.1 170717458 6107093 1389074..1390123 1 NC_010519.1 PFAM: inner-membrane translocator; KEGG: hso:HS_0764 ribose ABC transporter permease; monosaccharide-transporting ATPase 1390123 6107093 HSM_1231 Haemophilus somnus 2336 monosaccharide-transporting ATPase YP_001784555.1 1389074 D 228400 CDS YP_001784556.1 170717459 6107094 1390161..1391270 1 NC_010519.1 KEGG: hso:HS_0765 sugar ABC transporter periplasmic protein; sugar ABC transporter periplasmic protein 1391270 6107094 HSM_1232 Haemophilus somnus 2336 sugar ABC transporter periplasmic protein YP_001784556.1 1390161 D 228400 CDS YP_001784557.1 170717460 6107095 1391333..1392220 1 NC_010519.1 PFAM: SMP-30/gluconolaconase/LRE domain protein; KEGG: hso:HS_0766 conserved hypothetical protein; SMP-30/gluconolaconase/LRE domain-containing protein 1392220 6107095 HSM_1233 Haemophilus somnus 2336 SMP-30/gluconolaconase/LRE domain-containing protein YP_001784557.1 1391333 D 228400 CDS YP_001784558.1 170717461 6107096 complement(1392287..1393225) 1 NC_010519.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_0767 sugar ABC transporter periplasmic sugar-binding protein; monosaccharide-transporting ATPase 1393225 6107096 HSM_1234 Haemophilus somnus 2336 monosaccharide-transporting ATPase YP_001784558.1 1392287 R 228400 CDS YP_001784559.1 170717462 6107097 1393440..1394930 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0768 ribose ABC transporter ATP-binding protein; ABC transporter 1394930 6107097 HSM_1235 Haemophilus somnus 2336 ABC transporter YP_001784559.1 1393440 D 228400 CDS YP_001784560.1 170717463 6107098 1394939..1395967 1 NC_010519.1 PFAM: inner-membrane translocator; KEGG: hso:HS_0769 ribose transporter permease; monosaccharide-transporting ATPase 1395967 6107098 HSM_1236 Haemophilus somnus 2336 monosaccharide-transporting ATPase YP_001784560.1 1394939 D 228400 CDS YP_001784561.1 170717464 6107099 1396069..1397523 1 NC_010519.1 PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_0770 L-xylulose kinase; carbohydrate kinase FGGY 1397523 6107099 HSM_1237 Haemophilus somnus 2336 carbohydrate kinase FGGY YP_001784561.1 1396069 D 228400 CDS YP_001784562.1 170717465 6107100 1397534..1398181 1 NC_010519.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 1398181 ulaD 6107100 ulaD Haemophilus somnus 2336 3-keto-L-gulonate-6-phosphate decarboxylase YP_001784562.1 1397534 D 228400 CDS YP_001784563.1 170717466 6107101 1398198..1399070 1 NC_010519.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 1399070 6107101 HSM_1239 Haemophilus somnus 2336 L-xylulose 5-phosphate 3-epimerase YP_001784563.1 1398198 D 228400 CDS YP_001784564.1 170717468 6107102 1399064..1399759 1 NC_010519.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 1399759 sgbE 6107102 sgbE Haemophilus somnus 2336 L-ribulose-5-phosphate 4-epimerase YP_001784564.1 1399064 D 228400 CDS YP_001784565.1 170717469 6107104 complement(1399802..1400623) 1 NC_010519.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: hso:HS_0774 hydrolase, HAD superfamily; cof family hydrolase 1400623 6107104 HSM_1241 Haemophilus somnus 2336 cof family hydrolase YP_001784565.1 1399802 R 228400 CDS YP_001784566.1 170717470 6107105 1400862..1401818 1 NC_010519.1 PFAM: alpha/beta hydrolase; KEGG: hso:HS_0775 lysophospholipase L2; lysophospholipase 1401818 6107105 HSM_1242 Haemophilus somnus 2336 lysophospholipase YP_001784566.1 1400862 D 228400 CDS YP_001784567.1 170717471 6107106 complement(1401796..1402179) 1 NC_010519.1 TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; KEGG: hso:HS_0776 CrcB protein; CrcB protein 1402179 6107106 HSM_1243 Haemophilus somnus 2336 CrcB protein YP_001784567.1 1401796 R 228400 CDS YP_001784568.1 170717472 6107107 complement(1402199..1403017) 1 NC_010519.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: hso:HS_0777 hydrolase, haloacid dehalogenase-like family; cof family hydrolase 1403017 6107107 HSM_1244 Haemophilus somnus 2336 cof family hydrolase YP_001784568.1 1402199 R 228400 CDS YP_001784569.1 170717473 6107108 complement(1403055..1403717) 1 NC_010519.1 PFAM: nitroreductase; KEGG: hso:HS_0778 NAD(P)H nitroreductase; nitroreductase 1403717 6107108 HSM_1245 Haemophilus somnus 2336 nitroreductase YP_001784569.1 1403055 R 228400 CDS YP_001784570.1 170717474 6107109 complement(1403738..1404034) 1 NC_010519.1 PFAM: conserved hypothetical protein 743; KEGG: hso:HS_0779 hypothetical protein; hypothetical protein 1404034 6107109 HSM_1246 Haemophilus somnus 2336 hypothetical protein YP_001784570.1 1403738 R 228400 CDS YP_001784571.1 170717475 6107110 complement(1404059..1405270) 1 NC_010519.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; KEGG: hso:HS_0780 tyrosine-specific transporter; aromatic amino acid transporter 1405270 6107110 HSM_1247 Haemophilus somnus 2336 aromatic amino acid transporter YP_001784571.1 1404059 R 228400 CDS YP_001784572.1 170717476 6107111 complement(1405364..1406413) 1 NC_010519.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: hso:HS_0781 iron(III) ABC transporter ATP-binding protein; ABC transporter 1406413 6107111 HSM_1248 Haemophilus somnus 2336 ABC transporter YP_001784572.1 1405364 R 228400 CDS YP_001784573.1 170717477 6107112 complement(1406413..1408080) 1 NC_010519.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0782 iron-uptake permease inner membrane protein; binding-protein-dependent transporters inner membrane component 1408080 6107112 HSM_1249 Haemophilus somnus 2336 binding-protein-dependent transporters inner membrane component YP_001784573.1 1406413 R 228400 CDS YP_001784574.1 170717479 6107113 complement(1408237..1409253) 1 NC_010519.1 PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_0783 periplasmic iron-binding protein; extracellular solute-binding protein 1409253 6107113 HSM_1250 Haemophilus somnus 2336 extracellular solute-binding protein YP_001784574.1 1408237 R 228400 CDS YP_001784575.1 170717480 6107115 complement(1409444..1411141) 1 NC_010519.1 component of the membrane-bound D-lactate oxidase FAD-binding, NADH independent; D-lactate dehydrogenase 1411141 6107115 HSM_1251 Haemophilus somnus 2336 D-lactate dehydrogenase YP_001784575.1 1409444 R 228400 CDS YP_001784576.1 170717481 6107116 1411347..1412174 1 NC_010519.1 TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; PFAM: transferase hexapeptide repeat containing protein; KEGG: hso:HS_0785 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1412174 6107116 HSM_1252 Haemophilus somnus 2336 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_001784576.1 1411347 D 228400 CDS YP_001784577.1 170717482 6107117 complement(1412232..1413068) 1 NC_010519.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1413068 purU 6107117 purU Haemophilus somnus 2336 formyltetrahydrofolate deformylase YP_001784577.1 1412232 R 228400 CDS YP_001784578.1 170717483 6107118 complement(1413130..1413534) 1 NC_010519.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: hso:HS_0787 DNA-binding protein H-NS; histone family protein nucleoid-structuring protein H-NS 1413534 6107118 HSM_1254 Haemophilus somnus 2336 histone family protein nucleoid-structuring protein H-NS YP_001784578.1 1413130 R 228400 CDS YP_001784579.1 170717484 6107119 1413975..1415522 1 NC_010519.1 PFAM: Na? antiporter NhaC; KEGG: hso:HS_0788 Na(+)/H(+) antiporter; hypothetical protein 1415522 6107119 HSM_1255 Haemophilus somnus 2336 hypothetical protein YP_001784579.1 1413975 D 228400 CDS YP_001784580.1 170717485 6107120 1415647..1416663 1 NC_010519.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: hso:HS_0789 UDP-glucose-4-epimerase; UDP-glucose 4-epimerase 1416663 6107120 HSM_1256 Haemophilus somnus 2336 UDP-glucose 4-epimerase YP_001784580.1 1415647 D 228400 CDS YP_001784581.1 170717486 6107121 1417252..1431222 1 NC_010519.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790 large adhesin; YadA domain-containing protein 1431222 6107121 HSM_1257 Haemophilus somnus 2336 YadA domain-containing protein YP_001784581.1 1417252 D 228400 CDS YP_001784582.1 170717487 6107122 complement(1431330..1433366) 1 NC_010519.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: hso:HS_0791 oligopeptidase A; oligopeptidase A 1433366 6107122 HSM_1258 Haemophilus somnus 2336 oligopeptidase A YP_001784582.1 1431330 R 228400 CDS YP_001784583.1 170717488 6107123 1433653..1434843 1 NC_010519.1 PFAM: aminotransferase class I and II; KEGG: hso:HS_0792 aminotransferase; aspartate transaminase 1434843 6107123 HSM_1259 Haemophilus somnus 2336 aspartate transaminase YP_001784583.1 1433653 D 228400 CDS YP_001784584.1 170717490 6107124 1434833..1436242 1 NC_010519.1 TIGRFAM: Na+/H+ antiporter NhaC; PFAM: Na? antiporter NhaC; KEGG: hso:HS_0793 Na(+)/H(+) antiporter; Na+/H+ antiporter NhaC 1436242 6107124 HSM_1260 Haemophilus somnus 2336 Na+/H+ antiporter NhaC YP_001784584.1 1434833 D 228400 CDS YP_001784585.1 170717491 6107126 1436388..1437551 1 NC_010519.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: hso:HS_0794 xylose operon regulatory protein; helix-turn-helix domain-containing protein 1437551 6107126 HSM_1261 Haemophilus somnus 2336 helix-turn-helix domain-containing protein YP_001784585.1 1436388 D 228400 CDS YP_001784586.1 170717492 6107127 1437659..1438021 1 NC_010519.1 PFAM: protein of unknown function DUF454; KEGG: hso:HS_0795 hypothetical protein; hypothetical protein 1438021 6107127 HSM_1262 Haemophilus somnus 2336 hypothetical protein YP_001784586.1 1437659 D 228400 CDS YP_001784587.1 170717493 6107128 1438143..1439642 1 NC_010519.1 PFAM: extracellular solute-binding protein family 5; KEGG: hso:HS_0796 oligopeptide transporter periplasmic-binding protein; 4-phytase 1439642 6107128 HSM_1263 Haemophilus somnus 2336 4-phytase YP_001784587.1 1438143 D 228400 CDS YP_001784588.1 170717494 6107130 1441896..1443251 1 NC_010519.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: hso:HS_1548 outer membrane protein P1; aromatic hydrocarbon degradation membrane protein 1443251 6107130 HSM_1266 Haemophilus somnus 2336 aromatic hydrocarbon degradation membrane protein YP_001784588.1 1441896 D 228400 CDS YP_001784589.1 170717495 6107131 complement(1443357..1444010) 1 NC_010519.1 KEGG: hso:HS_1709 transposase; transposase 1444010 6107131 HSM_1267 Haemophilus somnus 2336 transposase YP_001784589.1 1443357 R 228400 CDS YP_001784590.1 170717496 6107132 complement(1444095..1445081) 1 NC_010519.1 PFAM: dihydroorotate dehydrogenase; KEGG: hso:HS_0799 hypothetical protein; dihydroorotate dehydrogenase 1445081 6107132 HSM_1268 Haemophilus somnus 2336 dihydroorotate dehydrogenase YP_001784590.1 1444095 R 228400 CDS YP_001784591.1 170717497 6107133 complement(1445445..1446674) 1 NC_010519.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: hso:HS_0800 tryptophan permease, tryptophan/tyrosine permease family; aromatic amino acid transporter 1446674 6107133 HSM_1269 Haemophilus somnus 2336 aromatic amino acid transporter YP_001784591.1 1445445 R 228400 CDS YP_001784592.1 170717499 6107134 complement(1446740..1448155) 1 NC_010519.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 1448155 tnaA 6107134 tnaA Haemophilus somnus 2336 tryptophanase YP_001784592.1 1446740 R 228400 CDS YP_001784593.1 170717500 6107136 complement(1448477..1450615) 1 NC_010519.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 1450615 6107136 HSM_1271 Haemophilus somnus 2336 phosphate acetyltransferase YP_001784593.1 1448477 R 228400 CDS YP_001784594.1 170717501 6107137 complement(1450683..1451879) 1 NC_010519.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1451879 6107137 HSM_1272 Haemophilus somnus 2336 acetate kinase YP_001784594.1 1450683 R 228400 CDS YP_001784595.1 170717502 6107138 1452110..1452544 1 NC_010519.1 PFAM: protein of unknown function DUF412; KEGG: hso:HS_0804 hypothetical protein; hypothetical protein 1452544 6107138 HSM_1273 Haemophilus somnus 2336 hypothetical protein YP_001784595.1 1452110 D 228400 CDS YP_001784596.1 170717503 6107139 1452657..1452935 1 NC_010519.1 PFAM: protein of unknown function DUF709; KEGG: hso:HS_0805 hypothetical protein; hypothetical protein 1452935 6107139 HSM_1274 Haemophilus somnus 2336 hypothetical protein YP_001784596.1 1452657 D 228400 CDS YP_001784597.1 170717504 6107140 complement(1453033..1455501) 1 NC_010519.1 TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: hso:HS_0806 trimethylamine-N-oxide reductase 2, biotin sulfoxide reductase; molybdopterin guanine dinucleotide-containing S/N-oxide reductase 1455501 6107140 HSM_1275 Haemophilus somnus 2336 molybdopterin guanine dinucleotide-containing S/N-oxide reductase YP_001784597.1 1453033 R 228400 CDS YP_001784598.1 170717505 6107141 complement(1455769..1456890) 1 NC_010519.1 PFAM: NapC/NirT cytochrome C domain protein; KEGG: hso:HS_0807 cytochrome C protein; NapC/NirT cytochrome C domain-containing protein 1456890 6107141 HSM_1276 Haemophilus somnus 2336 NapC/NirT cytochrome C domain-containing protein YP_001784598.1 1455769 R 228400 CDS YP_001784599.1 170717506 6107142 complement(1457077..1457802) 1 NC_010519.1 KEGG: hso:HS_0808 SAM-dependent methyltransferase; SAM-dependent methyltransferase 1457802 6107142 HSM_1277 Haemophilus somnus 2336 SAM-dependent methyltransferase YP_001784599.1 1457077 R 228400 CDS YP_001784600.1 170717507 6107143 1457836..1458537 1 NC_010519.1 PFAM: beta-lactamase; KEGG: hso:HS_0809 hydroxyacylglutathione hydrolase; hydroxyacylglutathione hydrolase 1458537 6107143 HSM_1278 Haemophilus somnus 2336 hydroxyacylglutathione hydrolase YP_001784600.1 1457836 D 228400 CDS YP_001784601.1 170717508 6107144 1458648..1459949 1 NC_010519.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1459949 hemA 6107144 hemA Haemophilus somnus 2336 glutamyl-tRNA reductase YP_001784601.1 1458648 D 228400 CDS YP_001784602.1 170717510 6107145 complement(1459961..1461355) 1 NC_010519.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1461355 6107145 HSM_1280 Haemophilus somnus 2336 multidrug efflux protein YP_001784602.1 1459961 R 228400 CDS YP_001784603.1 170717511 6107147 1461409..1462017 1 NC_010519.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1462017 6107147 HSM_1281 Haemophilus somnus 2336 riboflavin synthase subunit alpha YP_001784603.1 1461409 D 228400 CDS YP_001784604.1 170717512 6107148 complement(1462070..1463410) 1 NC_010519.1 PFAM: ATPase AAA; SMART: AAA ATPase; KEGG: hso:HS_0813 conserved hypothetical protein; recombination factor protein RarA 1463410 6107148 HSM_1282 Haemophilus somnus 2336 recombination factor protein RarA YP_001784604.1 1462070 R 228400 CDS YP_001784605.1 170717513 6107149 complement(1463476..1464090) 1 NC_010519.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1464090 lolA 6107149 lolA Haemophilus somnus 2336 outer-membrane lipoprotein carrier protein YP_001784605.1 1463476 R 228400 CDS YP_001784606.1 170717514 6107150 1464302..1464715 1 NC_010519.1 PFAM: protein of unknown function DUF1043; KEGG: hso:HS_0815 hypothetical protein; hypothetical protein 1464715 6107150 HSM_1284 Haemophilus somnus 2336 hypothetical protein YP_001784606.1 1464302 D 228400 CDS YP_001784607.1 170717515 6107151 1464832..1466232 1 NC_010519.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: hso:HS_0816 periplasmic serine protease; protease Do 1466232 6107151 HSM_1285 Haemophilus somnus 2336 protease Do YP_001784607.1 1464832 D 228400 CDS YP_001784608.1 170717516 6107152 complement(1466317..1466793) 1 NC_010519.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: hso:HS_0817 low molecular weight protein-tyrosine-phosphatase; protein tyrosine phosphatase 1466793 6107152 HSM_1286 Haemophilus somnus 2336 protein tyrosine phosphatase YP_001784608.1 1466317 R 228400 CDS YP_001784609.1 170717517 6107153 1466926..1467648 1 NC_010519.1 KEGG: hso:HS_0818 hypothetical protein; Mn2+-dependent serine/threonine protein kinase 1467648 6107153 HSM_1287 Haemophilus somnus 2336 Mn2+-dependent serine/threonine protein kinase YP_001784609.1 1466926 D 228400 CDS YP_001784610.1 170717518 6108890 1468073..1468534 1 NC_010519.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1468534 6108890 HSM_1288 Haemophilus somnus 2336 hypothetical protein YP_001784610.1 1468073 D 228400 CDS YP_001784611.1 170717519 6107155 1468549..1470030 1 NC_010519.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1470030 nusA 6107155 nusA Haemophilus somnus 2336 transcription elongation factor NusA YP_001784611.1 1468549 D 228400 CDS YP_001784612.1 170717521 6107156 1470051..1472546 1 NC_010519.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1472546 infB 6107156 infB Haemophilus somnus 2336 translation initiation factor IF-2 YP_001784612.1 1470051 D 228400 CDS YP_001784613.1 170717522 6107158 1472800..1473180 1 NC_010519.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1473180 rbfA 6107158 rbfA Haemophilus somnus 2336 ribosome-binding factor A YP_001784613.1 1472800 D 228400 CDS YP_001784614.1 170717523 6107159 1473193..1474119 1 NC_010519.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1474119 truB 6107159 truB Haemophilus somnus 2336 tRNA pseudouridine synthase B YP_001784614.1 1473193 D 228400 CDS YP_001784615.1 170717524 6107160 complement(1474167..1476440) 1 NC_010519.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 1476440 6107160 HSM_1293 Haemophilus somnus 2336 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_001784615.1 1474167 R 228400 CDS YP_001784616.1 170717525 6107161 complement(1476646..1478970) 1 NC_010519.1 TIGRFAM: penicillin-binding protein 1B; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: hso:HS_0825 penicillin-binding protein 1B; penicillin-binding protein 1B 1478970 6107161 HSM_1294 Haemophilus somnus 2336 penicillin-binding protein 1B YP_001784616.1 1476646 R 228400 CDS YP_001784617.1 170717526 6107162 complement(1478982..1479344) 1 NC_010519.1 PFAM: uncharacterised conserved protein UCP006287; KEGG: hso:HS_0826 hypothetical protein; hypothetical protein 1479344 6107162 HSM_1295 Haemophilus somnus 2336 hypothetical protein YP_001784617.1 1478982 R 228400 CDS YP_001784618.1 170717527 6107163 complement(1479348..1479689) 1 NC_010519.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: hso:HS_0827 HesB family protein; iron-sulfur cluster assembly accessory protein 1479689 6107163 HSM_1296 Haemophilus somnus 2336 iron-sulfur cluster assembly accessory protein YP_001784618.1 1479348 R 228400 CDS YP_001784619.1 170717528 6107164 1479791..1480612 1 NC_010519.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1480612 6107164 HSM_1297 Haemophilus somnus 2336 methionine aminopeptidase YP_001784619.1 1479791 D 228400 CDS YP_001784620.1 170717529 6107165 1480670..1483255 1 NC_010519.1 KEGG: hso:HS_0829 uridylyltransferase; TIGRFAM: protein-P-II uridylyltransferase; PFAM: amino acid-binding ACT domain protein; DNA polymerase beta domain protein region; metal-dependent phosphohydrolase HD sub domain; GlnD PII-uridylyltransferase; SMART: metal-dependent phosphohydrolase HD region; PII uridylyl-transferase 1483255 glnD 6107165 glnD Haemophilus somnus 2336 PII uridylyl-transferase YP_001784620.1 1480670 D 228400 CDS YP_001784621.1 170717530 6107166 1483334..1483807 1 NC_010519.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; subunit beta of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1483807 ribH 6107166 ribH Haemophilus somnus 2336 6,7-dimethyl-8-ribityllumazine synthase YP_001784621.1 1483334 D 228400 CDS YP_001784622.1 170717533 6107167 1483816..1484250 1 NC_010519.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1484250 nusB 6107167 nusB Haemophilus somnus 2336 transcription antitermination protein NusB YP_001784622.1 1483816 D 228400 CDS YP_001784623.1 170717534 6107170 1484265..1485272 1 NC_010519.1 TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein domain protein; KEGG: hso:HS_0832 thiamine-monophosphate kinase; thiamine-monophosphate kinase 1485272 6107170 HSM_1301 Haemophilus somnus 2336 thiamine-monophosphate kinase YP_001784623.1 1484265 D 228400 CDS YP_001784624.1 170717535 6107171 1485282..1485767 1 NC_010519.1 PFAM: phosphatidylglycerophosphatase A; KEGG: hso:HS_0833 phosphatidylglycerophosphatase A; phosphatidylglycerophosphatase A 1485767 6107171 HSM_1302 Haemophilus somnus 2336 phosphatidylglycerophosphatase A YP_001784624.1 1485282 D 228400 CDS YP_001784625.1 170717536 6107172 1485780..1486409 1 NC_010519.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: hso:HS_0834 lysine exporter protein; lysine exporter protein LysE/YggA 1486409 6107172 HSM_1303 Haemophilus somnus 2336 lysine exporter protein LysE/YggA YP_001784625.1 1485780 D 228400 CDS YP_001784626.1 170717537 6107173 1486428..1487240 1 NC_010519.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1487240 6107173 HSM_1304 Haemophilus somnus 2336 dihydrodipicolinate reductase YP_001784626.1 1486428 D 228400 CDS YP_001784627.1 170717538 6107174 1487407..1488210 1 NC_010519.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1488210 6107174 HSM_1305 Haemophilus somnus 2336 exonuclease III YP_001784627.1 1487407 D 228400 CDS YP_001784628.1 170717539 6107175 1488221..1489000 1 NC_010519.1 PFAM: protein of unknown function DUF1260; KEGG: hso:HS_0837 hypothetical protein; hypothetical protein 1489000 6107175 HSM_1306 Haemophilus somnus 2336 hypothetical protein YP_001784628.1 1488221 D 228400 CDS YP_001784629.1 170717540 6107176 complement(1489055..1490245) 1 NC_010519.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1490245 6107176 HSM_1307 Haemophilus somnus 2336 aromatic amino acid aminotransferase YP_001784629.1 1489055 R 228400 CDS YP_001784630.1 170717541 6107177 complement(1490390..1491478) 1 NC_010519.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1491478 6107177 HSM_1308 Haemophilus somnus 2336 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_001784630.1 1490390 R 228400 CDS YP_001784631.1 170717542 6107178 complement(1491521..1492213) 1 NC_010519.1 PFAM: carbonic anhydrase; KEGG: hso:HS_0840 carbonic anhydrase; carbonate dehydratase 1492213 6107178 HSM_1309 Haemophilus somnus 2336 carbonate dehydratase YP_001784631.1 1491521 R 228400 CDS YP_001784632.1 170717544 6107179 complement(1492323..1493132) 1 NC_010519.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1493132 trpA 6107179 trpA Haemophilus somnus 2336 tryptophan synthase subunit alpha YP_001784632.1 1492323 R 228400 CDS YP_001784633.1 170717545 6107181 complement(1493132..1494328) 1 NC_010519.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1494328 6107181 HSM_1311 Haemophilus somnus 2336 tryptophan synthase subunit beta YP_001784633.1 1493132 R 228400 CDS YP_001784634.1 170717546 6107182 complement(1494338..1495756) 1 NC_010519.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1495756 6107182 HSM_1312 Haemophilus somnus 2336 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_001784634.1 1494338 R 228400 CDS YP_001784635.1 170717547 6107183 complement(1495769..1496773) 1 NC_010519.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1496773 trpD 6107183 trpD Haemophilus somnus 2336 anthranilate phosphoribosyltransferase YP_001784635.1 1495769 R 228400 CDS YP_001784636.1 170717548 6107184 complement(1496818..1497423) 1 NC_010519.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1497423 6107184 HSM_1314 Haemophilus somnus 2336 anthranilate synthase component II YP_001784636.1 1496818 R 228400 CDS YP_001784637.1 170717549 6107185 complement(1497433..1498974) 1 NC_010519.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1498974 6107185 HSM_1315 Haemophilus somnus 2336 anthranilate synthase component I YP_001784637.1 1497433 R 228400 CDS YP_001784638.1 170717550 6107186 1499189..1500247 1 NC_010519.1 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1500247 6107186 HSM_1316 Haemophilus somnus 2336 periplasmic protease YP_001784638.1 1499189 D 228400 CDS YP_001784639.1 170717551 6107187 1500431..1501252 1 NC_010519.1 PFAM: OmpA/MotB domain protein; SmpA/OmlA domain protein; KEGG: hso:HS_0842 outer membrane protein; SmpA/OmlA domain-containing protein 1501252 6107187 HSM_1317 Haemophilus somnus 2336 SmpA/OmlA domain-containing protein YP_001784639.1 1500431 D 228400 CDS YP_001784640.1 170717552 6107188 complement(1501303..1502184) 1 NC_010519.1 PFAM: aminoglycoside phosphotransferase; fructosamine kinase; KEGG: hso:HS_0843 fructosamine kinase family enzyme; fructosamine kinase 1502184 6107188 HSM_1318 Haemophilus somnus 2336 fructosamine kinase YP_001784640.1 1501303 R 228400 CDS YP_001784641.1 170717553 6107189 1502565..1504493 1 NC_010519.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1504493 6107189 HSM_1319 Haemophilus somnus 2336 threonyl-tRNA synthetase YP_001784641.1 1502565 D 228400 CDS YP_001784642.1 170717555 6107190 complement(1504549..1505397) 1 NC_010519.1 PFAM: thioredoxin domain; KEGG: hso:HS_0845 conserved hypothetical protein; thioredoxin 1505397 6107190 HSM_1320 Haemophilus somnus 2336 thioredoxin YP_001784642.1 1504549 R 228400 CDS YP_001784643.1 170717556 6107192 1505734..1507044 1 NC_010519.1 PFAM: xanthine/uracil/vitamin C permease; KEGG: hso:HS_0846 permease, xanthine/uracil family; xanthine/uracil/vitamin C permease 1507044 6107192 HSM_1321 Haemophilus somnus 2336 xanthine/uracil/vitamin C permease YP_001784643.1 1505734 D 228400 CDS YP_001784644.1 170717557 6107193 1507126..1507662 1 NC_010519.1 PFAM: protein of unknown function DUF462; KEGG: hso:HS_0847 hypothetical protein; hypothetical protein 1507662 6107193 HSM_1322 Haemophilus somnus 2336 hypothetical protein YP_001784644.1 1507126 D 228400 CDS YP_001784645.1 170717558 6107194 1507663..1508592 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0848 ABC-type multidrug transporter, ATP-binding protein; ABC transporter 1508592 6107194 HSM_1323 Haemophilus somnus 2336 ABC transporter YP_001784645.1 1507663 D 228400 CDS YP_001784646.1 170717559 6107195 1508592..1509356 1 NC_010519.1 PFAM: ABC transporter; KEGG: hso:HS_0849 ABC-type multidrug transporter, permease; ABC transporter 1509356 6107195 HSM_1324 Haemophilus somnus 2336 ABC transporter YP_001784646.1 1508592 D 228400 CDS YP_001784647.1 170717560 6107196 complement(1509466..1510848) 1 NC_010519.1 PFAM: conserved hypothetical protein 730; KEGG: hso:HS_0850 conserved hypothetical protein; hypothetical protein 1510848 6107196 HSM_1325 Haemophilus somnus 2336 hypothetical protein YP_001784647.1 1509466 R 228400 CDS YP_001784648.1 170717561 6107197 complement(1510861..1511700) 1 NC_010519.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1511700 queF 6107197 queF Haemophilus somnus 2336 7-cyano-7-deazaguanine reductase YP_001784648.1 1510861 R 228400 CDS YP_001784649.1 170717562 6107198 complement(1511716..1512504) 1 NC_010519.1 KEGG: hso:HS_0852 hypothetical protein; hypothetical protein 1512504 6107198 HSM_1327 Haemophilus somnus 2336 hypothetical protein YP_001784649.1 1511716 R 228400 CDS YP_001784650.1 170717563 6107199 1512590..1512904 1 NC_010519.1 PFAM: protein of unknown function DUF446; KEGG: hso:HS_0853 hypothetical protein; hypothetical protein 1512904 6107199 HSM_1328 Haemophilus somnus 2336 hypothetical protein YP_001784650.1 1512590 D 228400 CDS YP_001784651.1 170717564 6107200 1512889..1513611 1 NC_010519.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 1513611 6107200 HSM_1329 Haemophilus somnus 2336 tRNA pseudouridine synthase C YP_001784651.1 1512889 D 228400 CDS YP_001784652.1 170717566 6107201 1513638..1513805 1 NC_010519.1 PFAM: protein of unknown function UPF0181; KEGG: hso:HS_0855 hypothetical protein; hypothetical protein 1513805 6107201 HSM_1330 Haemophilus somnus 2336 hypothetical protein YP_001784652.1 1513638 D 228400 CDS YP_001784653.1 170717567 6107203 1513955..1514164 1 NC_010519.1 TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: hso:HS_0856 cold shock-like protein; cold-shock DNA-binding domain-containing protein 1514164 6107203 HSM_1331 Haemophilus somnus 2336 cold-shock DNA-binding domain-containing protein YP_001784653.1 1513955 D 228400 CDS YP_001784654.1 170717568 6107204 complement(1514236..1514682) 1 NC_010519.1 PFAM: protein of unknown function DUF1047; KEGG: hso:HS_0857 hypothetical protein; hypothetical protein 1514682 6107204 HSM_1332 Haemophilus somnus 2336 hypothetical protein YP_001784654.1 1514236 R 228400 CDS YP_001784655.1 170717569 6107205 1514834..1516645 1 NC_010519.1 KEGG: hso:HS_0858 ATP-dependent Lon protease; ATP-dependent Lon protease 1516645 6107205 HSM_1333 Haemophilus somnus 2336 ATP-dependent Lon protease YP_001784655.1 1514834 D 228400 CDS YP_001784656.1 170717570 6107206 1516740..1517729 1 NC_010519.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1517729 pheS 6107206 pheS Haemophilus somnus 2336 phenylalanyl-tRNA synthetase subunit alpha YP_001784656.1 1516740 D 228400 CDS YP_001784657.1 170717571 6107207 1517744..1518223 1 NC_010519.1 KEGG: hso:HS_0860 hypothetical protein; hypothetical protein 1518223 6107207 HSM_1335 Haemophilus somnus 2336 hypothetical protein YP_001784657.1 1517744 D 228400 CDS YP_001784658.1 170717572 6107208 1518238..1520625 1 NC_010519.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1520625 pheT 6107208 pheT Haemophilus somnus 2336 phenylalanyl-tRNA synthetase subunit beta YP_001784658.1 1518238 D 228400 CDS YP_001784659.1 170717573 6107209 1520628..1520921 1 NC_010519.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1520921 ihfA 6107209 ihfA Haemophilus somnus 2336 integration host factor subunit alpha YP_001784659.1 1520628 D 228400 CDS YP_001784660.1 170717574 6107210 complement(1521065..1522009) 1 NC_010519.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1522009 6107210 HSM_1338 Haemophilus somnus 2336 C32 tRNA thiolase YP_001784660.1 1521065 R 228400 CDS YP_001784661.1 170717575 6107211 1522217..1523539 1 NC_010519.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1523539 6107211 HSM_1339 Haemophilus somnus 2336 condesin subunit F YP_001784661.1 1522217 D 228400 CDS YP_001784662.1 170717577 6107212 1523606..1524349 1 NC_010519.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1524349 6107212 HSM_1340 Haemophilus somnus 2336 condesin subunit E YP_001784662.1 1523606 D 228400 CDS YP_001784663.1 170717578 6107214 1524349..1528878 1 NC_010519.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1528878 mukB 6107214 mukB Haemophilus somnus 2336 cell division protein MukB YP_001784663.1 1524349 D 228400 CDS YP_001784664.1 170717579 6107216 1529865..1530719 1 NC_010519.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: hso:HS_0867 permease; hypothetical protein 1530719 6107216 HSM_1344 Haemophilus somnus 2336 hypothetical protein YP_001784664.1 1529865 D 228400 CDS YP_001784665.1 170717580 6107217 1530731..1531099 1 NC_010519.1 KEGG: hso:HS_0868 hypothetical protein; type I restriction-modification system methyltransferase subunit-like protein 1531099 6107217 HSM_1345 Haemophilus somnus 2336 type I restriction-modification system methyltransferase subunit-like protein YP_001784665.1 1530731 D 228400 CDS YP_001784666.1 170717581 6107218 1531209..1532270 1 NC_010519.1 KEGG: hso:HS_0870 hypothetical protein; hypothetical protein 1532270 6107218 HSM_1346 Haemophilus somnus 2336 hypothetical protein YP_001784666.1 1531209 D 228400 CDS YP_001784667.1 170717582 6107219 1532380..1532478 1 NC_010519.1 KEGG: hso:HS_0871 hypothetical protein; hypothetical protein 1532478 6107219 HSM_1347 Haemophilus somnus 2336 hypothetical protein YP_001784667.1 1532380 D 228400 CDS YP_001784668.1 170717583 6107220 1532521..1532637 1 NC_010519.1 KEGG: hso:HS_0871 hypothetical protein; hypothetical protein 1532637 6107220 HSM_1348 Haemophilus somnus 2336 hypothetical protein YP_001784668.1 1532521 D 228400 CDS YP_001784669.1 170717584 6107221 1532655..1532756 1 NC_010519.1 KEGG: sfr:Sfri_1956 type I site-specific deoxyribonuclease, HsdR family protein; type I site-specific deoxyribonuclease, HsdR family protein 1532756 6107221 HSM_1349 Haemophilus somnus 2336 type I site-specific deoxyribonuclease, HsdR family protein YP_001784669.1 1532655 D 228400 CDS YP_001784670.1 170717586 6107222 1532799..1534229 1 NC_010519.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 1534229 sbcB 6107222 sbcB Haemophilus somnus 2336 exonuclease I YP_001784670.1 1532799 D 228400 CDS YP_001784671.1 170717587 6107224 1534340..1534759 1 NC_010519.1 KEGG: bfs:BF2816 hypothetical protein; hypothetical protein 1534759 6107224 HSM_1351 Haemophilus somnus 2336 hypothetical protein YP_001784671.1 1534340 D 228400 CDS YP_001784672.1 170717588 6107225 complement(1535261..1535548) 1 NC_010519.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1535548 6107225 HSM_1352 Haemophilus somnus 2336 50S ribosomal protein L25 YP_001784672.1 1535261 R 228400 CDS YP_001784673.1 170717589 6107226 1535769..1536374 1 NC_010519.1 PFAM: SNARE associated Golgi protein; KEGG: hso:HS_0874 hypothetical protein; hypothetical protein 1536374 6107226 HSM_1353 Haemophilus somnus 2336 hypothetical protein YP_001784673.1 1535769 D 228400 CDS YP_001784674.1 170717590 6107227 complement(1536547..1536900) 1 NC_010519.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1536900 rplT 6107227 rplT Haemophilus somnus 2336 50S ribosomal protein L20 YP_001784674.1 1536547 R 228400 CDS YP_001784675.1 170717591 6107228 complement(1536971..1537168) 1 NC_010519.1 PFAM: ribosomal protein L35; KEGG: hso:HS_0876 50S ribosomal protein L35; 50S ribosomal protein L35 1537168 rpmI 6107228 rpmI Haemophilus somnus 2336 50S ribosomal protein L35 YP_001784675.1 1536971 R 228400 CDS YP_001784676.1 170717592 6107229 complement(1537267..1537746) 1 NC_010519.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1537746 infC 6107229 infC Haemophilus somnus 2336 translation initiation factor IF-3 YP_001784676.1 1537267 R 228400 CDS YP_001784677.1 170717593 6107230 1538170..1538943 1 NC_010519.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1538943 6107230 HSM_1357 Haemophilus somnus 2336 fumarate/nitrate reduction transcriptional regulator YP_001784677.1 1538170 D 228400 CDS YP_001784678.1 170717594 6107231 1539094..1540017 1 NC_010519.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1540017 6107231 HSM_1358 Haemophilus somnus 2336 universal stress protein UspE YP_001784678.1 1539094 D 228400 CDS YP_001784679.1 170717595 6107232 complement(1540062..1541393) 1 NC_010519.1 TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; KEGG: hso:HS_0880 folylpolyglutamate synthase; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 1541393 6107232 HSM_1359 Haemophilus somnus 2336 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_001784679.1 1540062 R 228400 CDS YP_001784680.1 170717597 6107233 complement(1541383..1542282) 1 NC_010519.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 1542282 6107233 HSM_1360 Haemophilus somnus 2336 acetyl-CoA carboxylase subunit beta YP_001784680.1 1541383 R 228400 CDS YP_001784681.1 170717598 6107235 complement(1542365..1543309) 1 NC_010519.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1543309 6107235 HSM_1361 Haemophilus somnus 2336 aspartate-semialdehyde dehydrogenase YP_001784681.1 1542365 R 228400 CDS YP_001784682.1 170717599 6107236 complement(1543414..1544241) 1 NC_010519.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: hso:HS_0883 TrpH protein; phosphotransferase domain-containing protein 1544241 6107236 HSM_1362 Haemophilus somnus 2336 phosphotransferase domain-containing protein YP_001784682.1 1543414 R 228400 CDS YP_001784683.1 170717600 6107237 complement(1544321..1546930) 1 NC_010519.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1 membrane alanine aminopeptidase; KEGG: hso:HS_0884 aminopeptidase N; aminopeptidase N 1546930 pepN 6107237 pepN Haemophilus somnus 2336 aminopeptidase N YP_001784683.1 1544321 R 228400 CDS YP_001784684.1 170717601 6107238 complement(1547039..1549498) 1 NC_010519.1 TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; KEGG: hso:HS_0885 glycogen phosphorylase; glycogen/starch/alpha-glucan phosphorylase 1549498 6107238 HSM_1364 Haemophilus somnus 2336 glycogen/starch/alpha-glucan phosphorylase YP_001784684.1 1547039 R 228400 CDS YP_001784685.1 170717602 6107239 complement(1549620..1551080) 1 NC_010519.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 1551080 glgA 6107239 glgA Haemophilus somnus 2336 glycogen synthase YP_001784685.1 1549620 R 228400 CDS YP_001784686.1 170717603 6107240 complement(1551129..1552439) 1 NC_010519.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1552439 glgC 6107240 glgC Haemophilus somnus 2336 glucose-1-phosphate adenylyltransferase YP_001784686.1 1551129 R 228400 CDS YP_001784687.1 170717604 6107241 complement(1552498..1554480) 1 NC_010519.1 TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: hso:HS_0888 glycogen operon protein; glycogen debranching protein GlgX 1554480 6107241 HSM_1367 Haemophilus somnus 2336 glycogen debranching protein GlgX YP_001784687.1 1552498 R 228400 CDS YP_001784688.1 170717605 6107242 complement(1554506..1556953) 1 NC_010519.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 1556953 6107242 HSM_1368 Haemophilus somnus 2336 glycogen branching protein YP_001784688.1 1554506 R 228400 CDS YP_001784689.1 170717606 6107243 complement(1556965..1559064) 1 NC_010519.1 TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77; KEGG: hso:HS_0890 4-alpha-glucanotransferase; 4-alpha-glucanotransferase 1559064 6107243 HSM_1369 Haemophilus somnus 2336 4-alpha-glucanotransferase YP_001784689.1 1556965 R 228400 CDS YP_001784690.1 170717608 6107244 complement(1559174..1559641) 1 NC_010519.1 PFAM: protein of unknown function UPF0153; KEGG: hso:HS_0891 hypothetical protein; hypothetical protein 1559641 6107244 HSM_1370 Haemophilus somnus 2336 hypothetical protein YP_001784690.1 1559174 R 228400 CDS YP_001784691.1 170717609 6107246 complement(1559731..1562514) 1 NC_010519.1 PFAM: peptidase M16 domain protein; KEGG: hso:HS_0892 zinc protease; peptidase M16 domain-containing protein 1562514 6107246 HSM_1371 Haemophilus somnus 2336 peptidase M16 domain-containing protein YP_001784691.1 1559731 R 228400 CDS YP_001784692.1 170717610 6107247 complement(1562514..1564901) 1 NC_010519.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0894 hypothetical protein; TonB-dependent receptor 1564901 6107247 HSM_1372 Haemophilus somnus 2336 TonB-dependent receptor YP_001784692.1 1562514 R 228400 CDS YP_001784693.1 170717611 6107248 complement(1565097..1566764) 1 NC_010519.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 1566764 6107248 HSM_1373 Haemophilus somnus 2336 glutaminyl-tRNA synthetase YP_001784693.1 1565097 R 228400 CDS YP_001784694.1 170717612 6107249 1566960..1567913 1 NC_010519.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: hso:HS_0896 hypothetical protein; hypothetical protein 1567913 6107249 HSM_1374 Haemophilus somnus 2336 hypothetical protein YP_001784694.1 1566960 D 228400 CDS YP_001784695.1 170717613 6107250 complement(1567900..1570989) 1 NC_010519.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: hso:HS_0897 tetrathionate reductase, subunit A; molybdopterin oxidoreductase 1570989 6107250 HSM_1375 Haemophilus somnus 2336 molybdopterin oxidoreductase YP_001784695.1 1567900 R 228400 CDS YP_001784696.1 170717614 6107251 complement(1570982..1572010) 1 NC_010519.1 PFAM: polysulphide reductase NrfD; KEGG: hso:HS_0898 tetrathionate reductase, subunit C; polysulfide reductase NrfD 1572010 6107251 HSM_1376 Haemophilus somnus 2336 polysulfide reductase NrfD YP_001784696.1 1570982 R 228400 CDS YP_001784697.1 170717615 6107252 complement(1572007..1572744) 1 NC_010519.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: hso:HS_0899 tetrathionate reductase, subunit B; 4Fe-4S ferredoxin 1572744 6107252 HSM_1377 Haemophilus somnus 2336 4Fe-4S ferredoxin YP_001784697.1 1572007 R 228400 CDS YP_001784698.1 170717616 6107253 1572996..1574660 1 NC_010519.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: hso:HS_0900 sensor kinase; histidine kinase 1574660 6107253 HSM_1378 Haemophilus somnus 2336 histidine kinase YP_001784698.1 1572996 D 228400 CDS YP_001784699.1 170717617 6107254 1574662..1575252 1 NC_010519.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: hso:HS_0901 two component response regulator; response regulator receiver protein 1575252 6107254 HSM_1379 Haemophilus somnus 2336 response regulator receiver protein YP_001784699.1 1574662 D 228400 CDS YP_001784700.1 170717619 6107255 complement(1575344..1576798) 1 NC_010519.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 1576798 6107255 HSM_1380 Haemophilus somnus 2336 thiamine biosynthesis protein ThiI YP_001784700.1 1575344 R 228400 CDS YP_001784701.1 170717620 6107257 1576988..1577239 1 NC_010519.1 TIGRFAM: exodeoxyribonuclease VII small subunit; PFAM: exonuclease VII small subunit; KEGG: hso:HS_0903 exodeoxyribonuclease VII small subunit; exodeoxyribonuclease VII small subunit 1577239 6107257 HSM_1381 Haemophilus somnus 2336 exodeoxyribonuclease VII small subunit YP_001784701.1 1576988 D 228400 CDS YP_001784702.1 170717621 6107258 1577255..1578145 1 NC_010519.1 PFAM: polyprenyl synthetase; KEGG: hso:HS_0904 farnesyl-diphosphate synthase; polyprenyl synthetase 1578145 6107258 HSM_1382 Haemophilus somnus 2336 polyprenyl synthetase YP_001784702.1 1577255 D 228400 CDS YP_001784703.1 170717622 6107259 1578178..1580031 1 NC_010519.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1580031 6107259 HSM_1383 Haemophilus somnus 2336 1-deoxy-D-xylulose-5-phosphate synthase YP_001784703.1 1578178 D 228400 CDS YP_001784704.1 170717623 6107260 1580289..1581197 1 NC_010519.1 PFAM: protein of unknown function DUF340 membrane; KEGG: hso:HS_0906 permease; hypothetical protein 1581197 6107260 HSM_1384 Haemophilus somnus 2336 hypothetical protein YP_001784704.1 1580289 D 228400 CDS YP_001784705.1 170717624 6107261 1581483..1581902 1 NC_010519.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1581902 6107261 HSM_1385 Haemophilus somnus 2336 3-hydroxydecanoyl-ACP dehydratase YP_001784705.1 1581483 D 228400 CDS YP_001784706.1 170717625 6107262 complement(1582016..1583881) 1 NC_010519.1 TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: hso:HS_0908 protease IV family; signal peptide peptidase SppA, 67K type 1583881 6107262 HSM_1386 Haemophilus somnus 2336 signal peptide peptidase SppA, 67K type YP_001784706.1 1582016 R 228400 CDS YP_001784707.1 170717626 6107263 1584009..1584563 1 NC_010519.1 PFAM: nitroreductase; KEGG: hso:HS_0909 nitroreductase family protein; nitroreductase 1584563 6107263 HSM_1387 Haemophilus somnus 2336 nitroreductase YP_001784707.1 1584009 D 228400 CDS YP_001784708.1 170717627 6107264 complement(1584629..1585285) 1 NC_010519.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1585285 folE 6107264 folE Haemophilus somnus 2336 GTP cyclohydrolase I YP_001784708.1 1584629 R 228400 CDS YP_001784709.1 170717628 6107265 1585432..1586646 1 NC_010519.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: hso:HS_0911 molybdopterin biosynthesis protein; molybdenum cofactor synthesis domain-containing protein 1586646 6107265 HSM_1389 Haemophilus somnus 2336 molybdenum cofactor synthesis domain-containing protein YP_001784709.1 1585432 D 228400 CDS YP_001784710.1 170717630 6107266 1586654..1587382 1 NC_010519.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 1587382 6107266 HSM_1390 Haemophilus somnus 2336 molybdopterin biosynthesis protein MoeB YP_001784710.1 1586654 D 228400 CDS YP_001784711.1 170717631 6107268 complement(1587455..1588087) 1 NC_010519.1 TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase; KEGG: hso:HS_0913 phosphoribosylglycinamide formyltransferase; phosphoribosylglycinamide formyltransferase 1588087 6107268 HSM_1391 Haemophilus somnus 2336 phosphoribosylglycinamide formyltransferase YP_001784711.1 1587455 R 228400 CDS YP_001784712.1 170717632 6107269 complement(1588300..1590906) 1 NC_010519.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1590906 6107269 HSM_1392 Haemophilus somnus 2336 DNA topoisomerase I YP_001784712.1 1588300 R 228400 CDS YP_001784713.1 170717633 6107270 complement(1591187..1591798) 1 NC_010519.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 1591798 6107270 HSM_1393 Haemophilus somnus 2336 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001784713.1 1591187 R 228400 CDS YP_001784714.1 170717634 6107271 complement(1591764..1593278) 1 NC_010519.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1593278 6107271 HSM_1394 Haemophilus somnus 2336 amidophosphoribosyltransferase YP_001784714.1 1591764 R 228400 CDS YP_001784715.1 170717635 6107272 complement(1593291..1593791) 1 NC_010519.1 PFAM: colicin V production protein; KEGG: hso:HS_0917 colicin V production protein; colicin V production protein 1593791 6107272 HSM_1395 Haemophilus somnus 2336 colicin V production protein YP_001784715.1 1593291 R 228400 CDS YP_001784716.1 170717636 6107273 1594486..1595421 1 NC_010519.1 TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: hso:HS_0918 polysialic acid capsule expression protein, KpsF/GutQ family protein; KpsF/GutQ family protein 1595421 6107273 HSM_1396 Haemophilus somnus 2336 KpsF/GutQ family protein YP_001784716.1 1594486 D 228400 CDS YP_001784717.1 170717637 6107274 1595426..1595977 1 NC_010519.1 TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: hso:HS_0919 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 1595977 6107274 HSM_1397 Haemophilus somnus 2336 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_001784717.1 1595426 D 228400 CDS YP_001784718.1 170717638 6107275 1596315..1596800 1 NC_010519.1 PFAM: ferritin; KEGG: hso:HS_0920 ferritin like protein 1; ferroxidase 1596800 6107275 HSM_1398 Haemophilus somnus 2336 ferroxidase YP_001784718.1 1596315 D 228400 CDS YP_001784719.1 170717639 6107276 1596817..1597314 1 NC_010519.1 PFAM: ferritin; KEGG: hso:HS_0921 ferritin like protein 2; ferroxidase 1597314 6107276 HSM_1399 Haemophilus somnus 2336 ferroxidase YP_001784719.1 1596817 D 228400 CDS YP_001784720.1 170717642 6107277 complement(1597536..1598291) 1 NC_010519.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: hso:HS_0922 transcriptional regulator, DeoR family; DeoR family transcriptional regulator 1598291 6107277 HSM_1400 Haemophilus somnus 2336 DeoR family transcriptional regulator YP_001784720.1 1597536 R 228400 CDS YP_001784721.1 170717643 6107280 complement(1598395..1599624) 1 NC_010519.1 KEGG: hso:HS_0923 hypothetical protein; hypothetical protein 1599624 6107280 HSM_1401 Haemophilus somnus 2336 hypothetical protein YP_001784721.1 1598395 R 228400 CDS YP_001784722.1 170717644 6107281 complement(1599621..1600619) 1 NC_010519.1 transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 1600619 6107281 HSM_1402 Haemophilus somnus 2336 2-keto-3-deoxygluconate permease YP_001784722.1 1599621 R 228400 CDS YP_001784723.1 170717645 6107282 complement(1600630..1601631) 1 NC_010519.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 1601631 pdxA 6107282 pdxA Haemophilus somnus 2336 4-hydroxythreonine-4-phosphate dehydrogenase YP_001784723.1 1600630 R 228400 CDS YP_001784724.1 170717646 6107283 1602051..1603415 1 NC_010519.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase 1603415 6107283 HSM_1404 Haemophilus somnus 2336 diaminobutyrate--2-oxoglutarate aminotransferase YP_001784724.1 1602051 D 228400 CDS YP_001784725.1 170717647 6107284 1603505..1605040 1 NC_010519.1 PFAM: pyridoxal-dependent decarboxylase; KEGG: hso:HS_0927 L-2,4-diaminobutyrate decarboxylase; pyridoxal-dependent decarboxylase 1605040 6107284 HSM_1405 Haemophilus somnus 2336 pyridoxal-dependent decarboxylase YP_001784725.1 1603505 D 228400 CDS YP_001784726.1 170717648 6107285 complement(1605157..1607181) 1 NC_010519.1 TIGRFAM: exodeoxyribonuclease V, subunit alpha; KEGG: hso:HS_0928 exodeoxyribonuclease V, alpha chain; exodeoxyribonuclease V subunit alpha 1607181 6107285 HSM_1406 Haemophilus somnus 2336 exodeoxyribonuclease V subunit alpha YP_001784726.1 1605157 R 228400 CDS YP_001784727.1 170717649 6107286 complement(1607181..1610831) 1 NC_010519.1 TIGRFAM: exodeoxyribonuclease V subunit beta; PFAM: UvrD/REP helicase; KEGG: hso:HS_0929 exodeoxyribonuclease V, beta chain; exodeoxyribonuclease V subunit beta 1610831 6107286 HSM_1407 Haemophilus somnus 2336 exodeoxyribonuclease V subunit beta YP_001784727.1 1607181 R 228400 CDS YP_001784728.1 170717650 6107287 complement(1610942..1611808) 1 NC_010519.1 metalloprotease; heat shock protein HtpX 1611808 6107287 HSM_1408 Haemophilus somnus 2336 heat shock protein HtpX YP_001784728.1 1610942 R 228400 CDS YP_001784729.1 170717651 6107288 complement(1611891..1612955) 1 NC_010519.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1612955 6107288 HSM_1409 Haemophilus somnus 2336 DNA polymerase IV YP_001784729.1 1611891 R 228400 CDS YP_001784730.1 170717653 6107289 1613276..1614229 1 NC_010519.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1614229 6107289 HSM_1410 Haemophilus somnus 2336 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_001784730.1 1613276 D 228400 CDS YP_001784731.1 170717654 6107291 1614298..1615158 1 NC_010519.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1615158 6107291 HSM_1411 Haemophilus somnus 2336 pyridoxamine kinase YP_001784731.1 1614298 D 228400 CDS YP_001784732.1 170717655 6107292 1615233..1616516 1 NC_010519.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; protein of unkown function DUF1946 PP-loop ATpase; KEGG: hso:HS_0934 cell-cycle protein; tRNA(Ile)-lysidine synthetase 1616516 6107292 HSM_1412 Haemophilus somnus 2336 tRNA(Ile)-lysidine synthetase YP_001784732.1 1615233 D 228400 CDS YP_001784733.1 170717656 6107293 complement(1616564..1618213) 1 NC_010519.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1618213 pgi 6107293 pgi Haemophilus somnus 2336 glucose-6-phosphate isomerase YP_001784733.1 1616564 R 228400 CDS YP_001784734.1 170717657 6107294 complement(1618241..1619320) 1 NC_010519.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1619320 alr 6107294 alr Haemophilus somnus 2336 alanine racemase YP_001784734.1 1618241 R 228400 CDS YP_001784735.1 170717658 6107295 complement(1619337..1620755) 1 NC_010519.1 unwinds double stranded DNA; replicative DNA helicase 1620755 6107295 HSM_1415 Haemophilus somnus 2336 replicative DNA helicase YP_001784735.1 1619337 R 228400 CDS YP_001784736.1 170717659 6107296 complement(1620907..1621986) 1 NC_010519.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1621986 6107296 HSM_1416 Haemophilus somnus 2336 phospho-2-dehydro-3-deoxyheptonate aldolase YP_001784736.1 1620907 R 228400 CDS YP_001784737.1 170717660 6107297 complement(1622093..1623343) 1 NC_010519.1 part of the ATP-dependent transporter LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1623343 6107297 HSM_1417 Haemophilus somnus 2336 outer membrane-specific lipoprotein transporter subunit LolE YP_001784737.1 1622093 R 228400 CDS YP_001784738.1 170717661 6107298 complement(1623340..1624023) 1 NC_010519.1 TIGRFAM: lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0943 lipoprotein releasing system, ATP-binding protein; lipoprotein releasing system, ATP-binding protein 1624023 6107298 HSM_1418 Haemophilus somnus 2336 lipoprotein releasing system, ATP-binding protein YP_001784738.1 1623340 R 228400 CDS YP_001784739.1 170717662 6107299 complement(1624044..1625234) 1 NC_010519.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: hso:HS_0944 lipoprotein releasing system, transmembrane protein; LolC/E family lipoprotein releasing system, transmembrane protein 1625234 6107299 HSM_1419 Haemophilus somnus 2336 LolC/E family lipoprotein releasing system, transmembrane protein YP_001784739.1 1624044 R 228400 CDS YP_001784740.1 170717664 6107300 complement(1625404..1626345) 1 NC_010519.1 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; glycerate dehydrogenase 1626345 6107300 HSM_1420 Haemophilus somnus 2336 glycerate dehydrogenase YP_001784740.1 1625404 R 228400 CDS YP_001784741.1 170717665 6107302 complement(1626457..1627311) 1 NC_010519.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1627311 6107302 HSM_1421 Haemophilus somnus 2336 2-dehydro-3-deoxyphosphooctonate aldolase YP_001784741.1 1626457 R 228400 CDS YP_001784742.1 170717666 6107303 complement(1627325..1628119) 1 NC_010519.1 KEGG: hso:HS_0947 hypothetical protein; hypothetical protein 1628119 6107303 HSM_1422 Haemophilus somnus 2336 hypothetical protein YP_001784742.1 1627325 R 228400 CDS YP_001784743.1 170717667 6107304 complement(1628103..1629008) 1 NC_010519.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: hso:HS_0948 peptide release factor glutamine N(5)-methylase; HemK family modification methylase 1629008 6107304 HSM_1423 Haemophilus somnus 2336 HemK family modification methylase YP_001784743.1 1628103 R 228400 CDS YP_001784744.1 170717668 6107305 complement(1629023..1629514) 1 NC_010519.1 PFAM: RDD domain containing protein; KEGG: hso:HS_0949 hypothetical protein; RDD domain-containing protein 1629514 6107305 HSM_1424 Haemophilus somnus 2336 RDD domain-containing protein YP_001784744.1 1629023 R 228400 CDS YP_001784745.1 170717669 6107306 complement(1629566..1630648) 1 NC_010519.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1630648 prfA 6107306 prfA Haemophilus somnus 2336 peptide chain release factor 1 YP_001784745.1 1629566 R 228400 CDS YP_001784746.1 170717670 6107307 complement(1630686..1631588) 1 NC_010519.1 PFAM: Lipooligosaccharide sialyltransferase; KEGG: hdu:HD0686 lipooligosaccharide sialyltransferase; lipooligosaccharide sialyltransferase 1631588 6107307 HSM_1426 Haemophilus somnus 2336 lipooligosaccharide sialyltransferase YP_001784746.1 1630686 R 228400 CDS YP_001784747.1 170717671 6107308 complement(1631712..1632173) 1 NC_010519.1 PFAM: 17 kDa surface antigen; KEGG: hso:HS_0952 outer membrane lipoprotein pcp precursor; 17 kDa surface antigen 1632173 6107308 HSM_1427 Haemophilus somnus 2336 17 kDa surface antigen YP_001784747.1 1631712 R 228400 CDS YP_001784748.1 170717672 6107309 complement(1632197..1632520) 1 NC_010519.1 KEGG: hso:HS_0953 hypothetical protein; hypothetical protein 1632520 6107309 HSM_1428 Haemophilus somnus 2336 hypothetical protein YP_001784748.1 1632197 R 228400 CDS YP_001784749.1 170717673 6107310 complement(1632526..1633113) 1 NC_010519.1 PFAM: protein of unknown function DUF991; KEGG: hso:HS_0954 hypothetical protein; hypothetical protein 1633113 6107310 HSM_1429 Haemophilus somnus 2336 hypothetical protein YP_001784749.1 1632526 R 228400 CDS YP_001784750.1 170717675 6107311 1633197..1634930 1 NC_010519.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1634930 argS 6107311 argS Haemophilus somnus 2336 arginyl-tRNA synthetase YP_001784750.1 1633197 D 228400 CDS YP_001784751.1 170717676 6107313 complement(1635004..1635876) 1 NC_010519.1 TIGRFAM: succinyl-CoA synthetase, subunit alpha; PFAM: CoA-binding protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: hso:HS_0956 succinyl-CoA synthetase, subunit alpha; succinyl-CoA synthetase subunit alpha 1635876 6107313 HSM_1431 Haemophilus somnus 2336 succinyl-CoA synthetase subunit alpha YP_001784751.1 1635004 R 228400 CDS YP_001784752.1 170717677 6107314 complement(1635876..1637045) 1 NC_010519.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1637045 sucC 6107314 sucC Haemophilus somnus 2336 succinyl-CoA synthetase subunit beta YP_001784752.1 1635876 R 228400 CDS YP_001784753.1 170717678 6107315 complement(1637099..1638322) 1 NC_010519.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: hso:HS_0958 dihydrolipoamide succinyltransferase; 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase 1638322 6107315 HSM_1433 Haemophilus somnus 2336 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase YP_001784753.1 1637099 R 228400 CDS YP_001784754.1 170717679 6107316 complement(1638411..1641206) 1 NC_010519.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 1641206 sucA 6107316 sucA Haemophilus somnus 2336 2-oxoglutarate dehydrogenase E1 component YP_001784754.1 1638411 R 228400 CDS YP_001784755.1 170717680 6107317 1641552..1642835 1 NC_010519.1 TIGRFAM: citrate synthase I; PFAM: citrate synthase; KEGG: hso:HS_0960 citrate synthase; citrate synthase I 1642835 6107317 HSM_1435 Haemophilus somnus 2336 citrate synthase I YP_001784755.1 1641552 D 228400 CDS YP_001784756.1 170717681 6107318 1642973..1644103 1 NC_010519.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 1644103 nrdB 6107318 nrdB Haemophilus somnus 2336 ribonucleotide-diphosphate reductase subunit beta YP_001784756.1 1642973 D 228400 CDS YP_001784757.1 170717682 6107319 1644169..1644426 1 NC_010519.1 PFAM: ferredoxin; KEGG: hso:HS_0962 ferredoxin 2Fe-2S type; ferredoxin 1644426 6107319 HSM_1437 Haemophilus somnus 2336 ferredoxin YP_001784757.1 1644169 D 228400 CDS YP_001784758.1 170717683 6107320 complement(1644480..1645676) 1 NC_010519.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 1645676 nhaA 6107320 nhaA Haemophilus somnus 2336 pH-dependent sodium/proton antiporter YP_001784758.1 1644480 R 228400 CDS YP_001784759.1 170717684 6107321 complement(1645854..1647206) 1 NC_010519.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 1647206 6107321 HSM_1439 Haemophilus somnus 2336 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_001784759.1 1645854 R 228400 CDS YP_001784760.1 170717686 6107322 1647368..1647871 1 NC_010519.1 PFAM: nuclease (SNase domain protein); KEGG: hso:HS_0966 nuclease; nuclease 1647871 6107322 HSM_1440 Haemophilus somnus 2336 nuclease YP_001784760.1 1647368 D 228400 CDS YP_001784761.1 170717687 6107324 1647861..1649060 1 NC_010519.1 PFAM: aminotransferase class V; KEGG: hso:HS_0967 cysteine desulfurase, aminotransferase, class V; class V aminotransferase 1649060 6107324 HSM_1441 Haemophilus somnus 2336 class V aminotransferase YP_001784761.1 1647861 D 228400 CDS YP_001784762.1 170717688 6107325 1649057..1649434 1 NC_010519.1 PFAM: Fe-S metabolism associated SufE; KEGG: hso:HS_0968 conserved hypothetical protein; Fe-S metabolism associated SufE 1649434 6107325 HSM_1442 Haemophilus somnus 2336 Fe-S metabolism associated SufE YP_001784762.1 1649057 D 228400 CDS YP_001784763.1 170717689 6107326 1650043..1650309 1 NC_010519.1 hypothetical protein 1650309 6107326 HSM_1443 Haemophilus somnus 2336 hypothetical protein YP_001784763.1 1650043 D 228400 CDS YP_001784764.1 170717690 6107327 1650254..1650916 1 NC_010519.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: xft:PD1006 cell filamentation protein; filamentation induced by cAMP protein fic 1650916 6107327 HSM_1444 Haemophilus somnus 2336 filamentation induced by cAMP protein fic YP_001784764.1 1650254 D 228400 CDS YP_001784765.1 170717691 6107328 1651203..1651496 1 NC_010519.1 TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; KEGG: hso:HS_0969 RelB protein; addiction module antitoxin 1651496 6107328 HSM_1445 Haemophilus somnus 2336 addiction module antitoxin YP_001784765.1 1651203 D 228400 CDS YP_001784766.1 170717692 6107329 1651489..1651761 1 NC_010519.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: hso:HS_0970 hypothetical protein; addiction module antitoxin 1651761 6107329 HSM_1446 Haemophilus somnus 2336 addiction module antitoxin YP_001784766.1 1651489 D 228400 CDS YP_001784767.1 170717693 6107330 complement(1651846..1652988) 1 NC_010519.1 PFAM: porin Gram-negative type; KEGG: hso:HS_0971 outer membrane protein, OmpH family; porin 1652988 6107330 HSM_1447 Haemophilus somnus 2336 porin YP_001784767.1 1651846 R 228400 CDS YP_001784768.1 170717694 6107331 1653426..1653707 1 NC_010519.1 PFAM: virulence-associated protein D (VapD) conserved region; KEGG: rpc:RPC_2389 virulence-associated protein D; virulence-associated protein D (VapD) region 1653707 6107331 HSM_1448 Haemophilus somnus 2336 virulence-associated protein D (VapD) region YP_001784768.1 1653426 D 228400 CDS YP_001784769.1 170717695 6107332 1653906..1654205 1 NC_010519.1 PFAM: protein of unknown function DUF1778; KEGG: hin:HI0420 hypothetical protein; hypothetical protein 1654205 6107332 HSM_1449 Haemophilus somnus 2336 hypothetical protein YP_001784769.1 1653906 D 228400 CDS YP_001784770.1 170717697 6107333 1654195..1654701 1 NC_010519.1 PFAM: GCN5-related N-acetyltransferase; KEGG: hso:HS_1675 histone acetyltransferase; N-acetyltransferase GCN5 1654701 6107333 HSM_1450 Haemophilus somnus 2336 N-acetyltransferase GCN5 YP_001784770.1 1654195 D 228400 CDS YP_001784771.1 170717698 6107335 complement(1654725..1655921) 1 NC_010519.1 PFAM: hypothetical protein; KEGG: hso:HS_0973 hypothetical protein; hypothetical protein 1655921 6107335 HSM_1451 Haemophilus somnus 2336 hypothetical protein YP_001784771.1 1654725 R 228400 CDS YP_001784772.1 170717699 6107336 complement(1655931..1656215) 1 NC_010519.1 PFAM: protein of unknown function DUF1049; KEGG: hso:HS_0974 hypothetical protein; hypothetical protein 1656215 6107336 HSM_1452 Haemophilus somnus 2336 hypothetical protein YP_001784772.1 1655931 R 228400 CDS YP_001784773.1 170717700 6107337 complement(1656335..1656619) 1 NC_010519.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1656619 ihfB 6107337 ihfB Haemophilus somnus 2336 integration host factor subunit beta YP_001784773.1 1656335 R 228400 CDS YP_001784774.1 170717701 6107338 complement(1656683..1658326) 1 NC_010519.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1658326 rpsA 6107338 rpsA Haemophilus somnus 2336 30S ribosomal protein S1 YP_001784774.1 1656683 R 228400 CDS YP_001784775.1 170717702 6107339 complement(1658399..1659112) 1 NC_010519.1 TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: hso:HS_0977 cytidylate kinase 1; cytidylate kinase 1659112 6107339 HSM_1455 Haemophilus somnus 2336 cytidylate kinase YP_001784775.1 1658399 R 228400 CDS YP_001784776.1 170717703 6107340 complement(1659165..1660190) 1 NC_010519.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 1660190 lpxD 6107340 lpxD Haemophilus somnus 2336 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_001784776.1 1659165 R 228400 CDS YP_001784777.1 170717704 6107341 complement(1660190..1660774) 1 NC_010519.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: hso:HS_0979 outer membrane protein; outer membrane chaperone Skp 1660774 6107341 HSM_1457 Haemophilus somnus 2336 outer membrane chaperone Skp YP_001784777.1 1660190 R 228400 CDS YP_001784778.1 170717705 6107342 complement(1660871..1663300) 1 NC_010519.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: hso:HS_0980 surface antigen; surface antigen (D15) 1663300 6107342 HSM_1458 Haemophilus somnus 2336 surface antigen (D15) YP_001784778.1 1660871 R 228400 CDS YP_001784779.1 170717706 6107343 complement(1663369..1664700) 1 NC_010519.1 TIGRFAM: membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: hso:HS_0981 zinc metalloprotease; membrane-associated zinc metalloprotease 1664700 6107343 HSM_1459 Haemophilus somnus 2336 membrane-associated zinc metalloprotease YP_001784779.1 1663369 R 228400 CDS YP_001784780.1 170717708 6107344 complement(1664709..1665572) 1 NC_010519.1 PFAM: phosphatidate cytidylyltransferase; KEGG: hso:HS_0982 phosphatidate cytidylyltransferase; phosphatidate cytidylyltransferase 1665572 6107344 HSM_1460 Haemophilus somnus 2336 phosphatidate cytidylyltransferase YP_001784780.1 1664709 R 228400 CDS YP_001784781.1 170717709 6107346 complement(1665585..1666310) 1 NC_010519.1 TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; KEGG: hso:HS_0983 undecaprenyl pyrophosphate synthase; undecaprenyl diphosphate synthase 1666310 6107346 HSM_1461 Haemophilus somnus 2336 undecaprenyl diphosphate synthase YP_001784781.1 1665585 R 228400 CDS YP_001784782.1 170717710 6107347 complement(1666493..1666999) 1 NC_010519.1 KEGG: hso:HS_0984 hypothetical protein; hypothetical protein 1666999 6107347 HSM_1462 Haemophilus somnus 2336 hypothetical protein YP_001784782.1 1666493 R 228400 CDS YP_001784783.1 170717711 6107348 complement(1667001..1668209) 1 NC_010519.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1668209 6107348 HSM_1463 Haemophilus somnus 2336 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_001784783.1 1667001 R 228400 CDS YP_001784784.1 170717712 6107349 complement(1668280..1668837) 1 NC_010519.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1668837 frr 6107349 frr Haemophilus somnus 2336 ribosome recycling factor YP_001784784.1 1668280 R 228400 CDS YP_001784785.1 170717713 6107350 complement(1668891..1669607) 1 NC_010519.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1669607 pyrH 6107350 pyrH Haemophilus somnus 2336 uridylate kinase YP_001784785.1 1668891 R 228400 CDS YP_001784786.1 170717714 6107351 complement(1669706..1670014) 1 NC_010519.1 KEGG: hso:HS_0988 hypothetical protein; hypothetical protein 1670014 6107351 HSM_1466 Haemophilus somnus 2336 hypothetical protein YP_001784786.1 1669706 R 228400 CDS YP_001784787.1 170717715 6107352 1670115..1670414 1 NC_010519.1 KEGG: hso:HS_0989 hypothetical protein; hypothetical protein 1670414 6107352 HSM_1467 Haemophilus somnus 2336 hypothetical protein YP_001784787.1 1670115 D 228400 CDS YP_001784788.1 170717716 6107353 1670493..1673189 1 NC_010519.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1673189 6107353 HSM_1468 Haemophilus somnus 2336 preprotein translocase subunit SecA YP_001784788.1 1670493 D 228400 CDS YP_001784789.1 170717717 6107354 1673236..1673634 1 NC_010519.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: hso:HS_0991 7,8-dihydro-8-oxoguanine-triphosphatase; mutator MutT protein 1673634 6107354 HSM_1469 Haemophilus somnus 2336 mutator MutT protein YP_001784789.1 1673236 D 228400 CDS YP_001784790.1 170717719 6107355 complement(1673702..1677613) 1 NC_010519.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1677613 6107355 HSM_1470 Haemophilus somnus 2336 ATP-dependent RNA helicase HrpA YP_001784790.1 1673702 R 228400 CDS YP_001784791.1 170717720 6107357 complement(1677660..1678115) 1 NC_010519.1 PFAM: protein of unknown function DUF441; KEGG: hso:HS_0993 permease; hypothetical protein 1678115 6107357 HSM_1471 Haemophilus somnus 2336 hypothetical protein YP_001784791.1 1677660 R 228400 CDS YP_001784792.1 170717721 6107358 1678428..1681067 1 NC_010519.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 1681067 6107358 HSM_1472 Haemophilus somnus 2336 phosphoenolpyruvate carboxylase YP_001784792.1 1678428 D 228400 CDS YP_001784793.1 170717722 6107359 1681170..1681493 1 NC_010519.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1681493 6107359 HSM_1473 Haemophilus somnus 2336 dsDNA-mimic protein YP_001784793.1 1681170 D 228400 CDS YP_001784794.1 170717723 6107360 complement(1681650..1682597) 1 NC_010519.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1682597 6107360 HSM_1474 Haemophilus somnus 2336 ribose-phosphate pyrophosphokinase YP_001784794.1 1681650 R 228400 CDS YP_001784795.1 170717724 6107361 complement(1682605..1683546) 1 NC_010519.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1683546 ipk 6107361 ipk Haemophilus somnus 2336 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_001784795.1 1682605 R 228400 CDS YP_001784796.1 170717725 6107362 complement(1683546..1684175) 1 NC_010519.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 1684175 lolB 6107362 lolB Haemophilus somnus 2336 outer membrane lipoprotein LolB YP_001784796.1 1683546 R 228400 CDS YP_001784797.1 170717726 6107363 1684353..1684622 1 NC_010519.1 KEGG: hso:HS_0999 hypothetical protein; hypothetical protein 1684622 6107363 HSM_1477 Haemophilus somnus 2336 hypothetical protein YP_001784797.1 1684353 D 228400 CDS YP_001784798.1 170717727 6107364 1684901..1685377 1 NC_010519.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1685377 greA 6107364 greA Haemophilus somnus 2336 transcription elongation factor GreA YP_001784798.1 1684901 D 228400 CDS YP_001784799.1 170717728 6107365 complement(1685432..1685728) 1 NC_010519.1 PFAM: protein of unknown function UPF0044; KEGG: hso:HS_1001 conserved hypothetical protein; hypothetical protein 1685728 6107365 HSM_1479 Haemophilus somnus 2336 hypothetical protein YP_001784799.1 1685432 R 228400 CDS YP_001784800.1 170717730 6107366 complement(1685845..1686195) 1 NC_010519.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: hso:HS_1002 arsenate reductase; arsenate reductase 1686195 6107366 HSM_1480 Haemophilus somnus 2336 arsenate reductase YP_001784800.1 1685845 R 228400 CDS YP_001784801.1 170717731 6107368 1686281..1687333 1 NC_010519.1 PFAM: protein of unknown function UPF0118; KEGG: hso:HS_1003 permease; hypothetical protein 1687333 6107368 HSM_1481 Haemophilus somnus 2336 hypothetical protein YP_001784801.1 1686281 D 228400 CDS YP_001784802.1 170717732 6107369 1687353..1688792 1 NC_010519.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 1688792 6107369 HSM_1482 Haemophilus somnus 2336 transglycosylase YP_001784802.1 1687353 D 228400 CDS YP_001784803.1 170717733 6107370 1688789..1688941 1 NC_010519.1 KEGG: hit:NTHI0339 hypothetical protein; hypothetical protein 1688941 6107370 HSM_1483 Haemophilus somnus 2336 hypothetical protein YP_001784803.1 1688789 D 228400 CDS YP_001784804.1 170717734 6107371 1689542..1696081 1 NC_010519.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1085 large adhesin; YadA domain-containing protein 1696081 6107371 HSM_1484 Haemophilus somnus 2336 YadA domain-containing protein YP_001784804.1 1689542 D 228400 CDS YP_001784805.1 170717735 6107372 complement(1696210..1697193) 1 NC_010519.1 KEGG: hso:HS_1010 biotin synthetase; TIGRFAM: biotin synthase; PFAM: radical SAM protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB; biotin synthase 1697193 6107372 HSM_1485 Haemophilus somnus 2336 biotin synthase YP_001784805.1 1696210 R 228400 CDS YP_001784806.1 170717736 6107373 complement(1697225..1697869) 1 NC_010519.1 TIGRFAM: ABC transporter ATPase, ThiQ subfamily; PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1011 thiamine ABC transporter ATP-binding protein; ABC transporter ATP-binding protein 1697869 6107373 HSM_1486 Haemophilus somnus 2336 ABC transporter ATP-binding protein YP_001784806.1 1697225 R 228400 CDS YP_001784807.1 170717737 6107374 complement(1697862..1699466) 1 NC_010519.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 1699466 thiP 6107374 thiP Haemophilus somnus 2336 thiamine transporter membrane protein YP_001784807.1 1697862 R 228400 CDS YP_001784808.1 170717738 6107375 complement(1699468..1700484) 1 NC_010519.1 TIGRFAM: ABC transporter periplasmic binding protein, thiB subfamily; thiamine ABC transporter periplasmic binding protein; KEGG: hso:HS_1013 thiamine ABC transporter periplasmic-binding protein; thiamine ABC transporter periplasmic binding protein 1700484 6107375 HSM_1488 Haemophilus somnus 2336 thiamine ABC transporter periplasmic binding protein YP_001784808.1 1699468 R 228400 CDS YP_001784809.1 170717739 6107376 complement(1701024..1713311) 1 NC_010519.1 TIGRFAM: cysteine protease domain, YopT-type; filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: filamentation induced by cAMP protein Fic; peptidase C58 Yersinia/Haemophilus virulence surface antigen; Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: pmu:PM0059 virulence factor, filamentous hemaglutinin; cysteine protease 1713311 6107376 HSM_1489 Haemophilus somnus 2336 cysteine protease YP_001784809.1 1701024 R 228400 CDS YP_001784810.1 170717741 6107377 complement(1713336..1715096) 1 NC_010519.1 PFAM: Hemolysin activator HlyB domain protein; polypeptide-transport-associated domain protein ShlB-type; KEGG: pmu:PM0056 hemolysin accessory protein; polypeptide-transport-associated domain-containing protein 1715096 6107377 HSM_1490 Haemophilus somnus 2336 polypeptide-transport-associated domain-containing protein YP_001784810.1 1713336 R 228400 CDS YP_001784811.1 170717742 6107379 1715441..1716799 1 NC_010519.1 PFAM: citrate transporter; Na? antiporter NhaC; KEGG: hso:HS_1014 conserved hypothetical protein; hypothetical protein 1716799 6107379 HSM_1491 Haemophilus somnus 2336 hypothetical protein YP_001784811.1 1715441 D 228400 CDS YP_001784812.1 170717743 6107380 1716847..1717440 1 NC_010519.1 KEGG: hso:HS_1015 hypothetical protein; hypothetical protein 1717440 6107380 HSM_1492 Haemophilus somnus 2336 hypothetical protein YP_001784812.1 1716847 D 228400 CDS YP_001784813.1 170717744 6107381 complement(1717475..1717648) 1 NC_010519.1 KEGG: hso:HS_1015a hypothetical protein; hypothetical protein 1717648 6107381 HSM_1493 Haemophilus somnus 2336 hypothetical protein YP_001784813.1 1717475 R 228400 CDS YP_001784814.1 170717745 6107382 complement(1717649..1718221) 1 NC_010519.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 1718221 6107382 HSM_1494 Haemophilus somnus 2336 RNA polymerase sigma factor YP_001784814.1 1717649 R 228400 CDS YP_001784815.1 170717746 6107383 1718307..1719260 1 NC_010519.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 1719260 6107383 HSM_1495 Haemophilus somnus 2336 sulfite oxidase subunit YedY YP_001784815.1 1718307 D 228400 CDS YP_001784816.1 170717747 6107384 1719260..1719859 1 NC_010519.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 1719859 6107384 HSM_1496 Haemophilus somnus 2336 sulfite oxidase subunit YedZ YP_001784816.1 1719260 D 228400 CDS YP_001784817.1 170717748 6107385 complement(1719961..1721226) 1 NC_010519.1 KEGG: hso:HS_1019 permease; permease 1721226 6107385 HSM_1497 Haemophilus somnus 2336 permease YP_001784817.1 1719961 R 228400 CDS YP_001784818.1 170717749 6108894 complement(1722059..1724215) 1 NC_010519.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1724215 rlmL 6108894 rlmL Haemophilus somnus 2336 23S rRNA m(2)G2445 methyltransferase YP_001784818.1 1722059 R 228400 CDS YP_001784819.1 170717750 6107387 complement(1724261..1726051) 1 NC_010519.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 1726051 6107387 HSM_1499 Haemophilus somnus 2336 lipid transporter ATP-binding/permease YP_001784819.1 1724261 R 228400 CDS YP_001784820.1 170717753 6107388 complement(1726061..1728439) 1 NC_010519.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase; ComEC/Rec2-related protein; KEGG: hso:HS_1022 recombination protein 2; DNA internalization-related competence protein ComEC/Rec2 1728439 6107388 HSM_1500 Haemophilus somnus 2336 DNA internalization-related competence protein ComEC/Rec2 YP_001784820.1 1726061 R 228400 CDS YP_001784821.1 170717754 6107391 1728786..1729223 1 NC_010519.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: hso:HS_1023 DnaK suppressor protein; TraR/DksA family transcriptional regulator 1729223 6107391 HSM_1501 Haemophilus somnus 2336 TraR/DksA family transcriptional regulator YP_001784821.1 1728786 D 228400 CDS YP_001784822.1 170717755 6107392 1729525..1730898 1 NC_010519.1 TIGRFAM: poly(A) polymerase; PFAM: polynucleotide adenylyltransferase region; KEGG: hso:HS_1024 poly(A) polymerase; poly(A) polymerase 1730898 6107392 HSM_1502 Haemophilus somnus 2336 poly(A) polymerase YP_001784822.1 1729525 D 228400 CDS YP_001784823.1 170717756 6107393 1730895..1731371 1 NC_010519.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: hso:HS_1025 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 1731371 6107393 HSM_1503 Haemophilus somnus 2336 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_001784823.1 1730895 D 228400 CDS YP_001784824.1 170717757 6107394 complement(1731469..1732617) 1 NC_010519.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 1732617 nagA 6107394 nagA Haemophilus somnus 2336 N-acetylglucosamine-6-phosphate deacetylase YP_001784824.1 1731469 R 228400 CDS YP_001784825.1 170717758 6107395 complement(1732630..1733436) 1 NC_010519.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 1733436 nagB 6107395 nagB Haemophilus somnus 2336 glucosamine-6-phosphate deaminase YP_001784825.1 1732630 R 228400 CDS YP_001784826.1 170717759 6107396 complement(1733668..1734120) 1 NC_010519.1 PFAM: molybdopterin biosynthesis MoaE protein; KEGG: hso:HS_1028 molybdopterin biosynthesis protein, E chain; molybdopterin biosynthesis MoaE protein 1734120 6107396 HSM_1506 Haemophilus somnus 2336 molybdopterin biosynthesis MoaE protein YP_001784826.1 1733668 R 228400 CDS YP_001784827.1 170717760 6107397 complement(1734121..1734366) 1 NC_010519.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 1734366 moaD 6107397 moaD Haemophilus somnus 2336 molybdopterin synthase small subunit YP_001784827.1 1734121 R 228400 CDS YP_001784828.1 170717761 6107398 complement(1734388..1734864) 1 NC_010519.1 TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; KEGG: hso:HS_1030 molybdenum cofactor biosynthesis protein, C chain; molybdenum cofactor biosynthesis protein C 1734864 6107398 HSM_1508 Haemophilus somnus 2336 molybdenum cofactor biosynthesis protein C YP_001784828.1 1734388 R 228400 CDS YP_001784829.1 170717762 6107399 complement(1734874..1735890) 1 NC_010519.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 1735890 moaA 6107399 moaA Haemophilus somnus 2336 molybdenum cofactor biosynthesis protein A YP_001784829.1 1734874 R 228400 CDS YP_001784830.1 170717764 6107400 1736162..1737163 1 NC_010519.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1737163 6107400 HSM_1510 Haemophilus somnus 2336 DNA-binding transcriptional repressor PurR YP_001784830.1 1736162 D 228400 CDS YP_001784831.1 170717765 6107402 complement(1737214..1738185) 1 NC_010519.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; CysB family transcripitonal regulator 1738185 cysB 6107402 cysB Haemophilus somnus 2336 CysB family transcripitonal regulator YP_001784831.1 1737214 R 228400 CDS YP_001784832.1 170717766 6107403 complement(1738247..1738573) 1 NC_010519.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: hso:HS_1034 glutaredoxin-like protein; glutaredoxin-like protein 1738573 6107403 HSM_1512 Haemophilus somnus 2336 glutaredoxin-like protein YP_001784832.1 1738247 R 228400 CDS YP_001784833.1 170717767 6107404 complement(1738675..1739703) 1 NC_010519.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: hso:HS_1035 hemagglutinin antigen; OmpA domain-containing protein 1739703 6107404 HSM_1513 Haemophilus somnus 2336 OmpA domain-containing protein YP_001784833.1 1738675 R 228400 CDS YP_001784834.1 170717768 6107405 complement(1739846..1741222) 1 NC_010519.1 PFAM: peptidase M23B; KEGG: hso:HS_1036 metalloprotease; peptidase M23B 1741222 6107405 HSM_1514 Haemophilus somnus 2336 peptidase M23B YP_001784834.1 1739846 R 228400 CDS YP_001784835.1 170717769 6107406 1741411..1742205 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1037 high-affinity zinc uptake system, ATP-binding protein; ABC transporter 1742205 6107406 HSM_1515 Haemophilus somnus 2336 ABC transporter YP_001784835.1 1741411 D 228400 CDS YP_001784836.1 170717770 6107407 1742215..1743000 1 NC_010519.1 PFAM: ABC transporter; KEGG: hso:HS_1038 high-affinity zinc uptake system, membrane protein; ABC transporter 1743000 6107407 HSM_1516 Haemophilus somnus 2336 ABC transporter YP_001784836.1 1742215 D 228400 CDS YP_001784837.1 170717771 6107408 complement(1743073..1744512) 1 NC_010519.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: hso:HS_1039 amino acid carrier protein; amino acid carrier protein 1744512 6107408 HSM_1517 Haemophilus somnus 2336 amino acid carrier protein YP_001784837.1 1743073 R 228400 CDS YP_001784838.1 170717772 6107409 complement(1744684..1745601) 1 NC_010519.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1745601 6107409 HSM_1518 Haemophilus somnus 2336 N-acetyl-D-glucosamine kinase YP_001784838.1 1744684 R 228400 CDS YP_001784839.1 170717773 6107410 complement(1745637..1746374) 1 NC_010519.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: hso:HS_1042 phosphatidylglycerophosphatase B; phosphatidylglycerophosphatase 1746374 6107410 HSM_1519 Haemophilus somnus 2336 phosphatidylglycerophosphatase YP_001784839.1 1745637 R 228400 CDS YP_001784840.1 170717775 6107411 1746467..1747117 1 NC_010519.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1747117 ribA 6107411 ribA Haemophilus somnus 2336 GTP cyclohydrolase II YP_001784840.1 1746467 D 228400 CDS YP_001784841.1 170717776 6107413 complement(1747439..1748563) 1 NC_010519.1 KEGG: hdu:HD1689 transposase; transposase 1748563 6107413 HSM_1521 Haemophilus somnus 2336 transposase YP_001784841.1 1747439 R 228400 CDS YP_001784842.1 170717777 6107414 1750248..1750766 1 NC_010519.1 hypothetical protein 1750766 6107414 HSM_1522 Haemophilus somnus 2336 hypothetical protein YP_001784842.1 1750248 D 228400 CDS YP_001784843.1 170717778 6107415 1750792..1751304 1 NC_010519.1 KEGG: dde:Dde_1416 hypothetical protein; hypothetical protein 1751304 6107415 HSM_1523 Haemophilus somnus 2336 hypothetical protein YP_001784843.1 1750792 D 228400 CDS YP_001784844.1 170717779 6107416 1751470..1752072 1 NC_010519.1 hypothetical protein 1752072 6107416 HSM_1524 Haemophilus somnus 2336 hypothetical protein YP_001784844.1 1751470 D 228400 CDS YP_001784845.1 170717780 6107417 1752082..1752618 1 NC_010519.1 KEGG: plu:plu0643 hypothetical protein; hypothetical protein 1752618 6107417 HSM_1525 Haemophilus somnus 2336 hypothetical protein YP_001784845.1 1752082 D 228400 CDS YP_001784846.1 170717781 6107418 1752864..1753844 1 NC_010519.1 KEGG: plu:plu0643 hypothetical protein; hypothetical protein 1753844 6107418 HSM_1526 Haemophilus somnus 2336 hypothetical protein YP_001784846.1 1752864 D 228400 CDS YP_001784847.1 170717782 6107419 complement(1754084..1754551) 1 NC_010519.1 KEGG: hdu:HD1698 hypothetical protein; hypothetical protein 1754551 6107419 HSM_1527 Haemophilus somnus 2336 hypothetical protein YP_001784847.1 1754084 R 228400 CDS YP_001784848.1 170717783 6107420 1754713..1757808 1 NC_010519.1 PFAM: FAD linked oxidase; KEGG: hso:HS_1044 conserved hypothetical protein; FAD linked oxidase domain-containing protein 1757808 6107420 HSM_1528 Haemophilus somnus 2336 FAD linked oxidase domain-containing protein YP_001784848.1 1754713 D 228400 CDS YP_001784849.1 170717784 6107421 1757825..1758247 1 NC_010519.1 PFAM: thioesterase superfamily protein; KEGG: hso:HS_1045 hypothetical protein; thioesterase superfamily protein 1758247 6107421 HSM_1529 Haemophilus somnus 2336 thioesterase superfamily protein YP_001784849.1 1757825 D 228400 CDS YP_001784850.1 170717786 6107422 1758306..1758857 1 NC_010519.1 KEGG: hso:HS_1046 permease; permease 1758857 6107422 HSM_1530 Haemophilus somnus 2336 permease YP_001784850.1 1758306 D 228400 CDS YP_001784851.1 170717787 6107424 1758698..1759828 1 NC_010519.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1759828 hemH 6107424 hemH Haemophilus somnus 2336 ferrochelatase YP_001784851.1 1758698 D 228400 CDS YP_001784852.1 170717788 6107425 1759971..1761017 1 NC_010519.1 PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_1048 spermidine/putrescine-binding periplasmic protein; extracellular solute-binding protein 1761017 6107425 HSM_1532 Haemophilus somnus 2336 extracellular solute-binding protein YP_001784852.1 1759971 D 228400 CDS YP_001784853.1 170717789 6107426 complement(1761123..1762169) 1 NC_010519.1 TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: hso:HS_1049 protease DegS precursor; periplasmic serine protease DegS 1762169 6107426 HSM_1533 Haemophilus somnus 2336 periplasmic serine protease DegS YP_001784853.1 1761123 R 228400 CDS YP_001784854.1 170717790 6107427 complement(1762189..1763319) 1 NC_010519.1 TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: hso:HS_1050 riboflavin biosynthesis protein; riboflavin biosynthesis protein RibD 1763319 6107427 HSM_1534 Haemophilus somnus 2336 riboflavin biosynthesis protein RibD YP_001784854.1 1762189 R 228400 CDS YP_001784855.1 170717791 6107428 complement(1763322..1763771) 1 NC_010519.1 PFAM: ATP-cone domain protein; KEGG: hso:HS_1051 conserved hypothetical protein; NrdR family transcripitonal regulator 1763771 nrdR 6107428 nrdR Haemophilus somnus 2336 NrdR family transcripitonal regulator YP_001784855.1 1763322 R 228400 CDS YP_001784856.1 170717792 6107429 complement(1763921..1764250) 1 NC_010519.1 PFAM: branched-chain amino acid ABC transporter; KEGG: hso:HS_1052 branched-chain amino acid ABC transporterer; branched-chain amino acid ABC transporter 1764250 6107429 HSM_1536 Haemophilus somnus 2336 branched-chain amino acid ABC transporter YP_001784856.1 1763921 R 228400 CDS YP_001784857.1 170717793 6107430 complement(1764261..1764992) 1 NC_010519.1 PFAM: AzlC family protein; KEGG: hso:HS_1053 branched-chain amino acid ABC transporterer; AzlC family protein 1764992 6107430 HSM_1537 Haemophilus somnus 2336 AzlC family protein YP_001784857.1 1764261 R 228400 CDS YP_001784858.1 170717794 6107431 complement(1765000..1765926) 1 NC_010519.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: hso:HS_1054 transcriptional regulator; LysR family transcriptional regulator 1765926 6107431 HSM_1538 Haemophilus somnus 2336 LysR family transcriptional regulator YP_001784858.1 1765000 R 228400 CDS YP_001784859.1 170717795 6107432 complement(1766063..1766998) 1 NC_010519.1 oxidizes malate to oxaloacetate; malate dehydrogenase 1766998 6107432 HSM_1539 Haemophilus somnus 2336 malate dehydrogenase YP_001784859.1 1766063 R 228400 CDS YP_001784860.1 170717797 6107433 1767222..1767689 1 NC_010519.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 1767689 6107433 HSM_1540 Haemophilus somnus 2336 arginine repressor YP_001784860.1 1767222 D 228400 CDS YP_001784861.1 170717798 6107435 1767711..1768598 1 NC_010519.1 PFAM: NAD-dependent epimerase/dehydratase; domain of unknown function DUF1731; KEGG: hso:HS_1057 conserved hypothetical protein; hypothetical protein 1768598 6107435 HSM_1541 Haemophilus somnus 2336 hypothetical protein YP_001784861.1 1767711 D 228400 CDS YP_001784862.1 170717799 6107436 complement(1768676..1775833) 1 NC_010519.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790 large adhesin; YadA domain-containing protein 1775833 6107436 HSM_1542 Haemophilus somnus 2336 YadA domain-containing protein YP_001784862.1 1768676 R 228400 CDS YP_001784863.1 170717800 6107437 1776512..1777093 1 NC_010519.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: hso:HS_1059 electron transport complex protein; Na(+)-translocating NADH-quinone reductase subunit E 1777093 6107437 HSM_1543 Haemophilus somnus 2336 Na(+)-translocating NADH-quinone reductase subunit E YP_001784863.1 1776512 D 228400 CDS YP_001784864.1 170717801 6107438 1777097..1777687 1 NC_010519.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transporter subunit RnfB 1777687 6107438 HSM_1544 Haemophilus somnus 2336 electron transporter subunit RnfB YP_001784864.1 1777097 D 228400 CDS YP_001784865.1 170717802 6107439 1777691..1779811 1 NC_010519.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transporter subunit RnfC 1779811 6107439 HSM_1545 Haemophilus somnus 2336 electron transporter subunit RnfC YP_001784865.1 1777691 D 228400 CDS YP_001784866.1 170717803 6107440 1779828..1780919 1 NC_010519.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transporter subunit RnfD 1780919 rnfD 6107440 rnfD Haemophilus somnus 2336 electron transporter subunit RnfD YP_001784866.1 1779828 D 228400 CDS YP_001784867.1 170717804 6107441 1780916..1781539 1 NC_010519.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transporter subunit RnfG 1781539 6107441 HSM_1547 Haemophilus somnus 2336 electron transporter subunit RnfG YP_001784867.1 1780916 D 228400 CDS YP_001784868.1 170717805 6107442 1781536..1782252 1 NC_010519.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transporter subunit RsxE 1782252 6107442 HSM_1548 Haemophilus somnus 2336 electron transporter subunit RsxE YP_001784868.1 1781536 D 228400 CDS YP_001784869.1 170717806 6107443 1782249..1782884 1 NC_010519.1 KEGG: hso:HS_1065 endonuclease III; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; endonuclease III 1782884 6107443 HSM_1549 Haemophilus somnus 2336 endonuclease III YP_001784869.1 1782249 D 228400 CDS YP_001784870.1 170717808 6107444 1782919..1784283 1 NC_010519.1 PFAM: sodium:neurotransmitter symporter; KEGG: hso:HS_1066 sodium-dependent transporter; sodium:neurotransmitter symporter 1784283 6107444 HSM_1550 Haemophilus somnus 2336 sodium:neurotransmitter symporter YP_001784870.1 1782919 D 228400 CDS YP_001784871.1 170717809 6107446 1784314..1784529 1 NC_010519.1 hypothetical protein 1784529 6107446 HSM_1551 Haemophilus somnus 2336 hypothetical protein YP_001784871.1 1784314 D 228400 CDS YP_001784872.1 170717810 6107447 1784493..1785083 1 NC_010519.1 KEGG: hso:HS_1067 hypothetical protein; hypothetical protein 1785083 6107447 HSM_1552 Haemophilus somnus 2336 hypothetical protein YP_001784872.1 1784493 D 228400 CDS YP_001784873.1 170717811 6107448 complement(1785163..1787808) 1 NC_010519.1 PFAM: hypothetical protein; KEGG: hso:HS_1068 hypothetical protein; hypothetical protein 1787808 6107448 HSM_1553 Haemophilus somnus 2336 hypothetical protein YP_001784873.1 1785163 R 228400 CDS YP_001784874.1 170717812 6107449 complement(1787786..1789039) 1 NC_010519.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: paraquat-inducible protein A; KEGG: hso:HS_1069 hypothetical protein; PqiA family integral membrane protein 1789039 6107449 HSM_1554 Haemophilus somnus 2336 PqiA family integral membrane protein YP_001784874.1 1787786 R 228400 CDS YP_001784875.1 170717813 6107450 1789251..1789886 1 NC_010519.1 affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 1789886 6107450 HSM_1555 Haemophilus somnus 2336 solute/DNA competence effector YP_001784875.1 1789251 D 228400 CDS YP_001784876.1 170717814 6107451 1789966..1791993 1 NC_010519.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 1791993 6107451 HSM_1556 Haemophilus somnus 2336 carboxy-terminal protease YP_001784876.1 1789966 D 228400 CDS YP_001784877.1 170717815 6107452 1792058..1793485 1 NC_010519.1 KEGG: hso:HS_1072 hypothetical protein; hypothetical protein 1793485 6107452 HSM_1557 Haemophilus somnus 2336 hypothetical protein YP_001784877.1 1792058 D 228400 CDS YP_001784878.1 170717816 6107453 1793562..1794125 1 NC_010519.1 PFAM: protein of unknown function DUF882; peptidase M15A; KEGG: hso:HS_1073 hypothetical protein; hypothetical protein 1794125 6107453 HSM_1558 Haemophilus somnus 2336 hypothetical protein YP_001784878.1 1793562 D 228400 CDS YP_001784879.1 170717817 6107454 1794201..1794833 1 NC_010519.1 PFAM: beta-lactamase; KEGG: hso:HS_1074 glyoxalase II family protein; beta-lactamase domain-containing protein 1794833 6107454 HSM_1559 Haemophilus somnus 2336 beta-lactamase domain-containing protein YP_001784879.1 1794201 D 228400 CDS YP_001784880.1 170717819 6107455 1794935..1796224 1 NC_010519.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1796224 6107455 HSM_1560 Haemophilus somnus 2336 seryl-tRNA synthetase YP_001784880.1 1794935 D 228400 CDS YP_001784881.1 170717820 6107457 complement(1796271..1797344) 1 NC_010519.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase 1797344 metX 6107457 metX Haemophilus somnus 2336 homoserine O-acetyltransferase YP_001784881.1 1796271 R 228400 CDS YP_001784882.1 170717821 6107458 1797532..1798227 1 NC_010519.1 PFAM: protein of unknown function DUF218; KEGG: hso:HS_1077 SanA protein; hypothetical protein 1798227 6107458 HSM_1562 Haemophilus somnus 2336 hypothetical protein YP_001784882.1 1797532 D 228400 CDS YP_001784883.1 170717822 6108895 1798957..1799928 1 NC_010519.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: hso:HS_1078 sodium/calcium exchange protein; CaCA family Na(+)/Ca(+) antiporter 1799928 6108895 HSM_1563 Haemophilus somnus 2336 CaCA family Na(+)/Ca(+) antiporter YP_001784883.1 1798957 D 228400 CDS YP_001784884.1 170717823 6107460 complement(1799949..1800956) 1 NC_010519.1 PFAM: high-affinity nickel-transporter; KEGG: hso:HS_1079 permease; high-affinity nickel-transporter 1800956 6107460 HSM_1564 Haemophilus somnus 2336 high-affinity nickel-transporter YP_001784884.1 1799949 R 228400 CDS YP_001784885.1 170717824 6107461 complement(1800947..1801588) 1 NC_010519.1 PFAM: protein of unknown function DUF1007; KEGG: hso:HS_1080 hypothetical protein; hypothetical protein 1801588 6107461 HSM_1565 Haemophilus somnus 2336 hypothetical protein YP_001784885.1 1800947 R 228400 CDS YP_001784886.1 170717825 6107462 1801820..1802290 1 NC_010519.1 PFAM: protein of unknown function UPF0079; KEGG: hso:HS_1081 ATPase; hypothetical protein 1802290 6107462 HSM_1566 Haemophilus somnus 2336 hypothetical protein YP_001784886.1 1801820 D 228400 CDS YP_001784887.1 170717826 6107463 1802294..1803502 1 NC_010519.1 PFAM: peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: hso:HS_1082 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase 1803502 6107463 HSM_1567 Haemophilus somnus 2336 N-acetylmuramoyl-L-alanine amidase YP_001784887.1 1802294 D 228400 CDS YP_001784888.1 170717827 6107464 1803518..1805365 1 NC_010519.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 1805365 mutL 6107464 mutL Haemophilus somnus 2336 DNA mismatch repair protein YP_001784888.1 1803518 D 228400 CDS YP_001784889.1 170717828 6107465 1805362..1806297 1 NC_010519.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1806297 miaA 6107465 miaA Haemophilus somnus 2336 tRNA delta(2)-isopentenylpyrophosphate transferase YP_001784889.1 1805362 D 228400 CDS YP_001784890.1 170717830 6107466 1806382..1806894 1 NC_010519.1 KEGG: mmu:673901 hypothetical protein LOC673901; hypothetical protein 1806894 6107466 HSM_1570 Haemophilus somnus 2336 hypothetical protein YP_001784890.1 1806382 D 228400 CDS YP_001784891.1 170717831 6107468 1806992..1818763 1 NC_010519.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790 large adhesin; YadA domain-containing protein 1818763 6107468 HSM_1571 Haemophilus somnus 2336 YadA domain-containing protein YP_001784891.1 1806992 D 228400 CDS YP_001784892.1 170717832 6107469 complement(1818885..1820309) 1 NC_010519.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1820309 6107469 HSM_1572 Haemophilus somnus 2336 (dimethylallyl)adenosine tRNA methylthiotransferase YP_001784892.1 1818885 R 228400 CDS YP_001784893.1 170717833 6107470 1820460..1821626 1 NC_010519.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: hso:HS_1156 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase 1821626 6107470 HSM_1573 Haemophilus somnus 2336 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase YP_001784893.1 1820460 D 228400 CDS YP_001784894.1 170717834 6107471 1821785..1822903 1 NC_010519.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 1822903 potA 6107471 potA Haemophilus somnus 2336 putrescine/spermidine ABC transporter ATPase YP_001784894.1 1821785 D 228400 CDS YP_001784895.1 170717835 6107472 1822887..1823747 1 NC_010519.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1823747 potB 6107472 potB Haemophilus somnus 2336 spermidine/putrescine ABC transporter membrane protein YP_001784895.1 1822887 D 228400 CDS YP_001784896.1 170717836 6107473 1823747..1824514 1 NC_010519.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1824514 potC 6107473 potC Haemophilus somnus 2336 spermidine/putrescine ABC transporter membrane protein YP_001784896.1 1823747 D 228400 CDS YP_001784897.1 170717837 6107474 1824678..1825763 1 NC_010519.1 PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_1160 spermidine/putrescine-binding periplasmic protein; extracellular solute-binding protein 1825763 6107474 HSM_1577 Haemophilus somnus 2336 extracellular solute-binding protein YP_001784897.1 1824678 D 228400 CDS YP_001784898.1 170717838 6107475 complement(1825819..1829253) 1 NC_010519.1 TIGRFAM: transcription-repair coupling factor; PFAM: helicase; transcription factor CarD; TRCF domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: hso:HS_1161 transcription-repair coupling factor; transcription-repair coupling factor 1829253 6107475 HSM_1578 Haemophilus somnus 2336 transcription-repair coupling factor YP_001784898.1 1825819 R 228400 CDS YP_001784899.1 170717839 6107476 complement(1829256..1829972) 1 NC_010519.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 1829972 6107476 HSM_1579 Haemophilus somnus 2336 3-demethylubiquinone-9 3-methyltransferase YP_001784899.1 1829256 R 228400 CDS YP_001784900.1 170717841 6107477 1830112..1832757 1 NC_010519.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1832757 6107477 HSM_1580 Haemophilus somnus 2336 DNA gyrase subunit A YP_001784900.1 1830112 D 228400 CDS YP_001784901.1 170717842 6107479 1832808..1832993 1 NC_010519.1 KEGG: hso:HS_1164 hypothetical protein; hypothetical protein 1832993 6107479 HSM_1581 Haemophilus somnus 2336 hypothetical protein YP_001784901.1 1832808 D 228400 CDS YP_001784902.1 170717843 6107480 1833119..1833445 1 NC_010519.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: hso:HS_1165 alkylphosphonate uptake protein; alkylphosphonate utilization operon protein PhnA 1833445 6107480 HSM_1582 Haemophilus somnus 2336 alkylphosphonate utilization operon protein PhnA YP_001784902.1 1833119 D 228400 CDS YP_001784903.1 170717844 6107481 1833482..1834699 1 NC_010519.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: hso:HS_1166 tyrosine-specific transporter; aromatic amino acid transporter 1834699 6107481 HSM_1583 Haemophilus somnus 2336 aromatic amino acid transporter YP_001784903.1 1833482 D 228400 CDS YP_001784904.1 170717845 6107482 complement(1834810..1836084) 1 NC_010519.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1836084 6107482 HSM_1584 Haemophilus somnus 2336 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001784904.1 1834810 R 228400 CDS YP_001784905.1 170717846 6107483 complement(1836104..1836355) 1 NC_010519.1 PFAM: BolA family protein; KEGG: hso:HS_1168 BolA-like protein; BolA family protein 1836355 6107483 HSM_1585 Haemophilus somnus 2336 BolA family protein YP_001784905.1 1836104 R 228400 CDS YP_001784906.1 170717847 6107484 complement(1836368..1836652) 1 NC_010519.1 KEGG: hso:HS_1169 conserved hypothetical protein; hypothetical protein 1836652 6107484 HSM_1586 Haemophilus somnus 2336 hypothetical protein YP_001784906.1 1836368 R 228400 CDS YP_001784907.1 170717848 6107485 complement(1836704..1837333) 1 NC_010519.1 PFAM: toluene tolerance family protein; KEGG: hso:HS_1170 conserved hypothetical protein; toluene tolerance family protein 1837333 6107485 HSM_1587 Haemophilus somnus 2336 toluene tolerance family protein YP_001784907.1 1836704 R 228400 CDS YP_001784908.1 170717849 6107486 complement(1837369..1837875) 1 NC_010519.1 PFAM: hypothetical protein; KEGG: hso:HS_1171 hypothetical protein; hypothetical protein 1837875 6107486 HSM_1588 Haemophilus somnus 2336 hypothetical protein YP_001784908.1 1837369 R 228400 CDS YP_001784909.1 170717850 6107487 complement(1837907..1838692) 1 NC_010519.1 PFAM: protein of unknown function DUF140; KEGG: hso:HS_1172 permease, ABC transporter; hypothetical protein 1838692 6107487 HSM_1589 Haemophilus somnus 2336 hypothetical protein YP_001784909.1 1837907 R 228400 CDS YP_001784910.1 170717852 6107488 complement(1838689..1839483) 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1173 ABC transporter ATP-binding protein; ABC transporter 1839483 6107488 HSM_1590 Haemophilus somnus 2336 ABC transporter YP_001784910.1 1838689 R 228400 CDS YP_001784911.1 170717853 6107490 1839703..1840278 1 NC_010519.1 PFAM: protein of unknown function DUF1239; KEGG: hso:HS_1174 hypothetical protein; hypothetical protein 1840278 6107490 HSM_1591 Haemophilus somnus 2336 hypothetical protein YP_001784911.1 1839703 D 228400 CDS YP_001784912.1 170717854 6107491 1840259..1840777 1 NC_010519.1 TIGRFAM: cell envelope biogenesis YhbN; PFAM: OstA family protein; KEGG: hso:HS_1175 hypothetical protein; cell envelope biogenesis YhbN 1840777 6107491 HSM_1592 Haemophilus somnus 2336 cell envelope biogenesis YhbN YP_001784912.1 1840259 D 228400 CDS YP_001784913.1 170717855 6107492 1840792..1841517 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1176 ABC transporter ATP-binding protein; ABC transporter 1841517 6107492 HSM_1593 Haemophilus somnus 2336 ABC transporter YP_001784913.1 1840792 D 228400 CDS YP_001784914.1 170717856 6107493 1841520..1842080 1 NC_010519.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: hso:HS_1177 nitrogen regulatory IIA protein; PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN 1842080 6107493 HSM_1594 Haemophilus somnus 2336 PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_001784914.1 1841520 D 228400 CDS YP_001784915.1 170717857 6107494 1842083..1842943 1 NC_010519.1 PFAM: uncharacterised P-loop ATPase protein UPF0042; KEGG: hso:HS_1178 hypothetical protein; hypothetical protein 1842943 6107494 HSM_1595 Haemophilus somnus 2336 hypothetical protein YP_001784915.1 1842083 D 228400 CDS YP_001784916.1 170717858 6107495 complement(1842979..1845030) 1 NC_010519.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1845030 metG 6107495 metG Haemophilus somnus 2336 methionyl-tRNA synthetase YP_001784916.1 1842979 R 228400 CDS YP_001784917.1 170717859 6107496 1845171..1846292 1 NC_010519.1 KEGG: hso:HS_1180 ATP-binding protein, MRP protein; ATPase 1846292 6107496 HSM_1597 Haemophilus somnus 2336 ATPase YP_001784917.1 1845171 D 228400 CDS YP_001784918.1 170717860 6107497 complement(1846733..1847038) 1 NC_010519.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: hit:NTHI0839 hypothetical protein; addiction module antitoxin 1847038 6107497 HSM_1598 Haemophilus somnus 2336 addiction module antitoxin YP_001784918.1 1846733 R 228400 CDS YP_001784919.1 170717861 6107498 complement(1847042..1847332) 1 NC_010519.1 TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; KEGG: hit:NTHI0838 DNA-damage-inducible protein J, negative regulator of translation; addiction module antitoxin 1847332 6107498 HSM_1599 Haemophilus somnus 2336 addiction module antitoxin YP_001784919.1 1847042 R 228400 CDS YP_001784920.1 170717864 6107499 complement(1847504..1848052) 1 NC_010519.1 KEGG: hso:HS_0574 oxidoreductase component; oxidoreductase component 1848052 6107499 HSM_1600 Haemophilus somnus 2336 oxidoreductase component YP_001784920.1 1847504 R 228400 CDS YP_001784921.1 170717865 6107502 complement(1848064..1848684) 1 NC_010519.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: hso:HS_0573 NAD(P)H2 dehydrogenase, quinone family; NAD(P)H dehydrogenase (quinone) 1848684 6107502 HSM_1601 Haemophilus somnus 2336 NAD(P)H dehydrogenase (quinone) YP_001784921.1 1848064 R 228400 CDS YP_001784922.1 170717866 6107503 complement(1848694..1849137) 1 NC_010519.1 PFAM: protein of unknown function DUF107; KEGG: hso:HS_0572 regulator of membrane protease activity; hypothetical protein 1849137 6107503 HSM_1602 Haemophilus somnus 2336 hypothetical protein YP_001784922.1 1848694 R 228400 CDS YP_001784923.1 170717867 6107504 complement(1849184..1850104) 1 NC_010519.1 PFAM: hypothetical protein; KEGG: hso:HS_0571 membrane protease band 7 family; hypothetical protein 1850104 6107504 HSM_1603 Haemophilus somnus 2336 hypothetical protein YP_001784923.1 1849184 R 228400 CDS YP_001784924.1 170717868 6107505 1850387..1850839 1 NC_010519.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 1850839 6107505 HSM_1604 Haemophilus somnus 2336 3-dehydroquinate dehydratase YP_001784924.1 1850387 D 228400 CDS YP_001784925.1 170717869 6107506 1851028..1851489 1 NC_010519.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: hso:HS_0569 acetyl-CoA carboxylase; acetyl-CoA carboxylase, biotin carboxyl carrier protein 1851489 6107506 HSM_1605 Haemophilus somnus 2336 acetyl-CoA carboxylase, biotin carboxyl carrier protein YP_001784925.1 1851028 D 228400 CDS YP_001784926.1 170717870 6107507 1851550..1852896 1 NC_010519.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 1852896 6107507 HSM_1606 Haemophilus somnus 2336 acetyl-CoA carboxylase biotin carboxylase subunit YP_001784926.1 1851550 D 228400 CDS YP_001784927.1 170717871 6107508 1853201..1854643 1 NC_010519.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 1854643 panF 6107508 panF Haemophilus somnus 2336 sodium/panthothenate symporter YP_001784927.1 1853201 D 228400 CDS YP_001784928.1 170717872 6107509 1854644..1855534 1 NC_010519.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 1855534 prmA 6107509 prmA Haemophilus somnus 2336 50S ribosomal protein L11 YP_001784928.1 1854644 D 228400 CDS YP_001784929.1 170717873 6107510 1855721..1856704 1 NC_010519.1 TIGRFAM: hypothetical protein; PFAM: dihydrouridine synthase; dihydroorotate dehydrogenase; KEGG: hso:HS_0565 tRNA-dihydrouridine synthase B; nifR3 family TIM-barrel protein 1856704 6107510 HSM_1609 Haemophilus somnus 2336 nifR3 family TIM-barrel protein YP_001784929.1 1855721 D 228400 CDS YP_001784930.1 170717875 6107511 1856698..1856994 1 NC_010519.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 1856994 fis 6107511 fis Haemophilus somnus 2336 DNA-binding protein Fis YP_001784930.1 1856698 D 228400 CDS YP_001784931.1 170717876 6107513 complement(1857043..1858041) 1 NC_010519.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 1858041 6107513 HSM_1611 Haemophilus somnus 2336 O-succinylbenzoate synthase YP_001784931.1 1857043 R 228400 CDS YP_001784932.1 170717877 6107514 complement(1858255..1859112) 1 NC_010519.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 1859112 6107514 HSM_1612 Haemophilus somnus 2336 naphthoate synthase YP_001784932.1 1858255 R 228400 CDS YP_001784933.1 170717878 6107515 complement(1859399..1860700) 1 NC_010519.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1860700 eno 6107515 eno Haemophilus somnus 2336 phosphopyruvate hydratase YP_001784933.1 1859399 R 228400 CDS YP_001784934.1 170717879 6107516 1860940..1861518 1 NC_010519.1 KEGG: hso:HS_0560 type I restriction enzyme, specificity subunit; type I restriction enzyme, specificity subunit 1861518 6107516 HSM_1614 Haemophilus somnus 2336 type I restriction enzyme, specificity subunit YP_001784934.1 1860940 D 228400 CDS YP_001784935.1 170717880 6107517 1861511..1864711 1 NC_010519.1 TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases; KEGG: hso:HS_0559 type I site-specific deoxyribonuclease, restriction subunit; HsdR family type I site-specific deoxyribonuclease 1864711 6107517 HSM_1615 Haemophilus somnus 2336 HsdR family type I site-specific deoxyribonuclease YP_001784935.1 1861511 D 228400 CDS YP_001784936.1 170717881 6107518 1864717..1865697 1 NC_010519.1 PFAM: Abi family protein; KEGG: noc:Noc_1806 abortive infection bacteriophage resistance protein; Abi family protein 1865697 6107518 HSM_1616 Haemophilus somnus 2336 Abi family protein YP_001784936.1 1864717 D 228400 CDS YP_001784937.1 170717882 6107519 1865787..1867019 1 NC_010519.1 PFAM: restriction modification system DNA specificity domain; KEGG: hso:HS_0556 type I restriction enzyme, specificity subunit; restriction modification system DNA specificity subunit 1867019 6107519 HSM_1617 Haemophilus somnus 2336 restriction modification system DNA specificity subunit YP_001784937.1 1865787 D 228400 CDS YP_001784938.1 170717883 6107520 1867032..1867592 1 NC_010519.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: hin:HI0977 cell filamentation protein; filamentation induced by cAMP protein fic 1867592 6107520 HSM_1618 Haemophilus somnus 2336 filamentation induced by cAMP protein fic YP_001784938.1 1867032 D 228400 CDS YP_001784939.1 170717884 6107521 1867646..1869259 1 NC_010519.1 TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: llc:LACR_1215 type I restriction-modification system methyltransferase subunit; type I restriction-modification system, M subunit 1869259 6107521 HSM_1619 Haemophilus somnus 2336 type I restriction-modification system, M subunit YP_001784939.1 1867646 D 228400 CDS YP_001784940.1 170717886 6107522 1869566..1869862 1 NC_010519.1 KEGG: mfa:Mfla_1216 restriction modification system DNA specificity domain; restriction modification system DNA specificity subunit 1869862 6107522 HSM_1620 Haemophilus somnus 2336 restriction modification system DNA specificity subunit YP_001784940.1 1869566 D 228400 CDS YP_001784941.1 170717887 6107524 1869884..1870810 1 NC_010519.1 PFAM: phage integrase family protein; KEGG: hso:HS_0555 phage integrase; phage integrase family protein 1870810 6107524 HSM_1621 Haemophilus somnus 2336 phage integrase family protein YP_001784941.1 1869884 D 228400 CDS YP_001784942.1 170717888 6107525 complement(1870823..1871338) 1 NC_010519.1 KEGG: yps:YPTB0536 type I restriction enzyme, S subunit; type I restriction enzyme, S subunit 1871338 6107525 HSM_1622 Haemophilus somnus 2336 type I restriction enzyme, S subunit YP_001784942.1 1870823 R 228400 CDS YP_001784943.1 170717889 6107526 complement(1871444..1871668) 1 NC_010519.1 hypothetical protein 1871668 6107526 HSM_1623 Haemophilus somnus 2336 hypothetical protein YP_001784943.1 1871444 R 228400 CDS YP_001784944.1 170717890 6107527 1871683..1872711 1 NC_010519.1 PFAM: acyltransferase 3; KEGG: hso:HS_0553 acetyltransferase; acyltransferase 3 1872711 6107527 HSM_1624 Haemophilus somnus 2336 acyltransferase 3 YP_001784944.1 1871683 D 228400 CDS YP_001784945.1 170717891 6107528 complement(1872727..1873143) 1 NC_010519.1 PFAM: transposase IS200-family protein; KEGG: hso:HS_1391 transposase; transposase IS200-family protein 1873143 6107528 HSM_1625 Haemophilus somnus 2336 transposase IS200-family protein YP_001784945.1 1872727 R 228400 CDS YP_001784946.1 170717892 6107529 1873190..1874326 1 NC_010519.1 TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: hso:HS_0583 transposase; IS605 family transposase OrfB 1874326 6107529 HSM_1626 Haemophilus somnus 2336 IS605 family transposase OrfB YP_001784946.1 1873190 D 228400 CDS YP_001784947.1 170717893 6107530 1874609..1874896 1 NC_010519.1 KEGG: hso:HS_0525 hypothetical protein; hypothetical protein 1874896 6107530 HSM_1627 Haemophilus somnus 2336 hypothetical protein YP_001784947.1 1874609 D 228400 CDS YP_001784948.1 170717894 6107531 1875023..1875286 1 NC_010519.1 KEGG: hso:HS_0527 hypothetical protein; hypothetical protein 1875286 6107531 HSM_1628 Haemophilus somnus 2336 hypothetical protein YP_001784948.1 1875023 D 228400 CDS YP_001784949.1 170717895 6107532 1875423..1875914 1 NC_010519.1 KEGG: hso:HS_0528 hypothetical protein; hypothetical protein 1875914 6107532 HSM_1629 Haemophilus somnus 2336 hypothetical protein YP_001784949.1 1875423 D 228400 CDS YP_001784950.1 170717897 6107533 1875907..1876092 1 NC_010519.1 hypothetical protein 1876092 6107533 HSM_1630 Haemophilus somnus 2336 hypothetical protein YP_001784950.1 1875907 D 228400 CDS YP_001784951.1 170717898 6107535 complement(1876215..1877351) 1 NC_010519.1 TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: hso:HS_0583 transposase; IS605 family transposase OrfB 1877351 6107535 HSM_1631 Haemophilus somnus 2336 IS605 family transposase OrfB YP_001784951.1 1876215 R 228400 CDS YP_001784952.1 170717899 6107536 1877398..1877814 1 NC_010519.1 PFAM: transposase IS200-family protein; KEGG: hso:HS_1391 transposase; transposase IS200-family protein 1877814 6107536 HSM_1632 Haemophilus somnus 2336 transposase IS200-family protein YP_001784952.1 1877398 D 228400 CDS YP_001784953.1 170717900 6107537 complement(1877974..1878402) 1 NC_010519.1 hypothetical protein 1878402 6107537 HSM_1633 Haemophilus somnus 2336 hypothetical protein YP_001784953.1 1877974 R 228400 CDS YP_001784954.1 170717901 6107538 complement(1879063..1879773) 1 NC_010519.1 KEGG: plu:plu0225 hypothetical protein; hypothetical protein 1879773 6107538 HSM_1634 Haemophilus somnus 2336 hypothetical protein YP_001784954.1 1879063 R 228400 CDS YP_001784955.1 170717902 6107539 complement(1879770..1880156) 1 NC_010519.1 KEGG: ngo:NGO1591 hypothetical protein; hypothetical protein 1880156 6107539 HSM_1635 Haemophilus somnus 2336 hypothetical protein YP_001784955.1 1879770 R 228400 CDS YP_001784956.1 170717903 6107540 complement(1880159..1880308) 1 NC_010519.1 KEGG: nme:NMB0372 hypothetical protein; hypothetical protein 1880308 6107540 HSM_1636 Haemophilus somnus 2336 hypothetical protein YP_001784956.1 1880159 R 228400 CDS YP_001784957.1 170717904 6107541 complement(1880376..1880621) 1 NC_010519.1 hypothetical protein 1880621 6107541 HSM_1637 Haemophilus somnus 2336 hypothetical protein YP_001784957.1 1880376 R 228400 CDS YP_001784958.1 170717905 6107542 complement(1880626..1882686) 1 NC_010519.1 KEGG: msu:MS1164 hypothetical protein; hypothetical protein 1882686 6107542 HSM_1638 Haemophilus somnus 2336 hypothetical protein YP_001784958.1 1880626 R 228400 CDS YP_001784959.1 170717906 6107543 complement(1883603..1884052) 1 NC_010519.1 hypothetical protein 1884052 6107543 HSM_1639 Haemophilus somnus 2336 hypothetical protein YP_001784959.1 1883603 R 228400 CDS YP_001784960.1 170717908 6107544 complement(1884363..1884803) 1 NC_010519.1 KEGG: plu:plu1354 hypothetical protein; hypothetical protein 1884803 6107544 HSM_1640 Haemophilus somnus 2336 hypothetical protein YP_001784960.1 1884363 R 228400 CDS YP_001784961.1 170717909 6107546 complement(1884812..1886914) 1 NC_010519.1 KEGG: msu:MS1167 FhaB protein; hypothetical protein 1886914 6107546 HSM_1641 Haemophilus somnus 2336 hypothetical protein YP_001784961.1 1884812 R 228400 CDS YP_001784962.1 170717910 6107547 complement(1887064..1887519) 1 NC_010519.1 hypothetical protein 1887519 6107547 HSM_1642 Haemophilus somnus 2336 hypothetical protein YP_001784962.1 1887064 R 228400 CDS YP_001784963.1 170717911 6107548 complement(1887521..1887772) 1 NC_010519.1 KEGG: bld:BLi01315 YeeF; hypothetical protein 1887772 6107548 HSM_1643 Haemophilus somnus 2336 hypothetical protein YP_001784963.1 1887521 R 228400 CDS YP_001784964.1 170717912 6107549 complement(1888067..1888423) 1 NC_010519.1 hypothetical protein 1888423 6107549 HSM_1644 Haemophilus somnus 2336 hypothetical protein YP_001784964.1 1888067 R 228400 CDS YP_001784965.1 170717913 6107550 complement(1888675..1888926) 1 NC_010519.1 hypothetical protein 1888926 6107550 HSM_1645 Haemophilus somnus 2336 hypothetical protein YP_001784965.1 1888675 R 228400 CDS YP_001784966.1 170717914 6107551 complement(1888923..1890218) 1 NC_010519.1 PFAM: Cytotoxic domain protein; KEGG: cvi:CV2871 probable hemagglutinin; cytotoxic domain-containing protein 1890218 6107551 HSM_1646 Haemophilus somnus 2336 cytotoxic domain-containing protein YP_001784966.1 1888923 R 228400 CDS YP_001784967.1 170717915 6107552 complement(1890444..1892567) 1 NC_010519.1 KEGG: msu:MS1163 FhaB protein; FhaB protein 1892567 6107552 HSM_1647 Haemophilus somnus 2336 FhaB protein YP_001784967.1 1890444 R 228400 CDS YP_001784968.1 170717916 6107553 complement(1892583..1892975) 1 NC_010519.1 hypothetical protein 1892975 6107553 HSM_1648 Haemophilus somnus 2336 hypothetical protein YP_001784968.1 1892583 R 228400 CDS YP_001784969.1 170717917 6107554 complement(1892975..1893256) 1 NC_010519.1 hypothetical protein 1893256 6107554 HSM_1649 Haemophilus somnus 2336 hypothetical protein YP_001784969.1 1892975 R 228400 CDS YP_001784970.1 170717919 6107555 complement(1893295..1893780) 1 NC_010519.1 hypothetical protein 1893780 6107555 HSM_1650 Haemophilus somnus 2336 hypothetical protein YP_001784970.1 1893295 R 228400 CDS YP_001784971.1 170717920 6107557 complement(1893785..1902019) 1 NC_010519.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: msu:MS1167 FhaB protein; filamentous hemagglutinin outer membrane protein 1902019 6107557 HSM_1651 Haemophilus somnus 2336 filamentous hemagglutinin outer membrane protein YP_001784971.1 1893785 R 228400 CDS YP_001784972.1 170717921 6107558 complement(1901988..1902182) 1 NC_010519.1 KEGG: msu:MS1169 FhaC protein; hypothetical protein 1902182 6107558 HSM_1652 Haemophilus somnus 2336 hypothetical protein YP_001784972.1 1901988 R 228400 CDS YP_001784973.1 170717922 6107559 complement(1902170..1902466) 1 NC_010519.1 hypothetical protein 1902466 6107559 HSM_1653 Haemophilus somnus 2336 hypothetical protein YP_001784973.1 1902170 R 228400 CDS YP_001784974.1 170717923 6107560 complement(1902931..1903641) 1 NC_010519.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: hso:HS_0541 conserved hypothetical protein; hypothetical protein 1903641 6107560 HSM_1654 Haemophilus somnus 2336 hypothetical protein YP_001784974.1 1902931 R 228400 CDS YP_001784975.1 170717924 6107561 1903824..1904609 1 NC_010519.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; methyltransferase type 11; methyltransferase type 12; KEGG: hso:HS_0542 ubiquinone/menaquinone biosynthesis methyltransferase; ubiquinone/menaquinone biosynthesis methyltransferase 1904609 6107561 HSM_1655 Haemophilus somnus 2336 ubiquinone/menaquinone biosynthesis methyltransferase YP_001784975.1 1903824 D 228400 CDS YP_001784976.1 170717925 6107562 1904618..1905253 1 NC_010519.1 PFAM: protein of unknown function DUF1243; KEGG: hso:HS_0543 conserved hypothetical protein; hypothetical protein 1905253 6107562 HSM_1656 Haemophilus somnus 2336 hypothetical protein YP_001784976.1 1904618 D 228400 CDS YP_001784977.1 170717926 6107563 1905250..1906887 1 NC_010519.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: hso:HS_0544 ubiquinone biosynthesis protein; 2-polyprenylphenol 6-hydroxylase 1906887 6107563 HSM_1657 Haemophilus somnus 2336 2-polyprenylphenol 6-hydroxylase YP_001784977.1 1905250 D 228400 CDS YP_001784978.1 170717927 6107564 1906992..1907213 1 NC_010519.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: hso:HS_0545 sec-independent protein translocase protein, TatA/E family; twin arginine-targeting protein translocase 1907213 6107564 HSM_1658 Haemophilus somnus 2336 twin arginine-targeting protein translocase YP_001784978.1 1906992 D 228400 CDS YP_001784979.1 170717928 6107565 1907217..1907771 1 NC_010519.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; KEGG: hso:HS_0546 sec-independent protein translocase protein; twin-arginine translocation protein subunit TatB 1907771 6107565 HSM_1659 Haemophilus somnus 2336 twin-arginine translocation protein subunit TatB YP_001784979.1 1907217 D 228400 CDS YP_001784980.1 170717930 6107566 1907768..1908505 1 NC_010519.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: hso:HS_0547 sec-independent protein translocase protein; Sec-independent protein translocase subunit TatC 1908505 6107566 HSM_1660 Haemophilus somnus 2336 Sec-independent protein translocase subunit TatC YP_001784980.1 1907768 D 228400 CDS YP_001784981.1 170717931 6107568 1908571..1909593 1 NC_010519.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 1909593 6107568 HSM_1661 Haemophilus somnus 2336 delta-aminolevulinic acid dehydratase YP_001784981.1 1908571 D 228400 CDS YP_001784982.1 170717932 6107569 complement(1909650..1910894) 1 NC_010519.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1910894 purT 6107569 purT Haemophilus somnus 2336 phosphoribosylglycinamide formyltransferase 2 YP_001784982.1 1909650 R 228400 CDS YP_001784983.1 170717933 6107570 complement(1910872..1911378) 1 NC_010519.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 1911378 6107570 HSM_1663 Haemophilus somnus 2336 S-ribosylhomocysteinase YP_001784983.1 1910872 R 228400 CDS YP_001784984.1 170717934 6107571 1911659..1913665 1 NC_010519.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1913665 6107571 HSM_1664 Haemophilus somnus 2336 transketolase YP_001784984.1 1911659 D 228400 CDS YP_001784985.1 170717935 6107572 complement(1913858..1914580) 1 NC_010519.1 KEGG: net:Neut_2561 type III restriction enzyme, res subunit; type III restriction enzyme, res subunit 1914580 6107572 HSM_1665 Haemophilus somnus 2336 type III restriction enzyme, res subunit YP_001784985.1 1913858 R 228400 CDS YP_001784986.1 170717936 6107573 complement(1914598..1918695) 1 NC_010519.1 PFAM: helicase; type III restriction protein res subunit; SMART: DEAD-like helicases; KEGG: net:Neut_2561 type III restriction enzyme, res subunit; type III restriction protein res subunit 1918695 6107573 HSM_1666 Haemophilus somnus 2336 type III restriction protein res subunit YP_001784986.1 1914598 R 228400 CDS YP_001784987.1 170717937 6107574 complement(1919115..1919243) 1 NC_010519.1 KEGG: hso:HS_0638 Lob1 protein; Lob1 protein 1919243 6107574 HSM_1667 Haemophilus somnus 2336 Lob1 protein YP_001784987.1 1919115 R 228400 CDS YP_001784988.1 170717938 6107575 1919528..1921156 1 NC_010519.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1921156 pyrG 6107575 pyrG Haemophilus somnus 2336 CTP synthetase YP_001784988.1 1919528 D 228400 CDS YP_001784989.1 170717939 6107576 complement(1921204..1922079) 1 NC_010519.1 KEGG: hso:HS_0553 acetyltransferase; acetyltransferase 1922079 6107576 HSM_1669 Haemophilus somnus 2336 acetyltransferase YP_001784989.1 1921204 R 228400 CDS YP_001784990.1 170717941 6107577 complement(1922216..1923352) 1 NC_010519.1 TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: hso:HS_0583 transposase; IS605 family transposase OrfB 1923352 6107577 HSM_1670 Haemophilus somnus 2336 IS605 family transposase OrfB YP_001784990.1 1922216 R 228400 CDS YP_001784991.1 170717942 6107579 1923399..1923815 1 NC_010519.1 PFAM: transposase IS200-family protein; KEGG: hso:HS_1391 transposase; transposase IS200-family protein 1923815 6107579 HSM_1671 Haemophilus somnus 2336 transposase IS200-family protein YP_001784991.1 1923399 D 228400 CDS YP_001784992.1 170717943 6107580 complement(1923959..1924198) 1 NC_010519.1 KEGG: hso:HS_0524 hypothetical protein; hypothetical protein 1924198 6107580 HSM_1672 Haemophilus somnus 2336 hypothetical protein YP_001784992.1 1923959 R 228400 CDS YP_001784993.1 170717944 6107581 complement(1924199..1924444) 1 NC_010519.1 KEGG: hso:HS_0523 hypothetical protein; hypothetical protein 1924444 6107581 HSM_1673 Haemophilus somnus 2336 hypothetical protein YP_001784993.1 1924199 R 228400 CDS YP_001784994.1 170717945 6107582 complement(1924454..1924675) 1 NC_010519.1 PFAM: prophage CP4-57 regulator; KEGG: hso:HS_0522 phage transcriptional regulator; phage transcriptional regulator AlpA 1924675 6107582 HSM_1674 Haemophilus somnus 2336 phage transcriptional regulator AlpA YP_001784994.1 1924454 R 228400 CDS YP_001784995.1 170717946 6107583 complement(1924840..1925814) 1 NC_010519.1 hypothetical protein 1925814 6107583 HSM_1675 Haemophilus somnus 2336 hypothetical protein YP_001784995.1 1924840 R 228400 CDS YP_001784996.1 170717947 6107584 complement(1926347..1927594) 1 NC_010519.1 PFAM: phage integrase family protein; KEGG: hso:HS_0519 phage integrase; phage integrase family protein 1927594 6107584 HSM_1676 Haemophilus somnus 2336 phage integrase family protein YP_001784996.1 1926347 R 228400 CDS YP_001784997.1 170717948 6107585 1928343..1928921 1 NC_010519.1 KEGG: efa:EF3160 hypothetical protein; hypothetical protein 1928921 6107585 HSM_1677 Haemophilus somnus 2336 hypothetical protein YP_001784997.1 1928343 D 228400 CDS YP_001784998.1 170717949 6107586 complement(1929653..1930090) 1 NC_010519.1 KEGG: plu:plu4544 hypothetical protein; hypothetical protein 1930090 6107586 HSM_1678 Haemophilus somnus 2336 hypothetical protein YP_001784998.1 1929653 R 228400 CDS YP_001784999.1 170717950 6107587 1930240..1931139 1 NC_010519.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: hso:HS_0001 integrase; phage integrase family protein 1931139 6107587 HSM_1679 Haemophilus somnus 2336 phage integrase family protein YP_001784999.1 1930240 D 228400 CDS YP_001785000.1 170717952 6107588 1931538..1932512 1 NC_010519.1 PFAM: Integrase catalytic region; KEGG: ssp:SSP1423 transposase; integrase catalytic region 1932512 6107588 HSM_1680 Haemophilus somnus 2336 integrase catalytic region YP_001785000.1 1931538 D 228400 CDS YP_001785001.1 170717953 6107590 complement(1932585..1933382) 1 NC_010519.1 KEGG: hit:NTHI0153 type I restriction enzyme M subunit; type I restriction enzyme M subunit 1933382 6107590 HSM_1681 Haemophilus somnus 2336 type I restriction enzyme M subunit YP_001785001.1 1932585 R 228400 CDS YP_001785002.1 170717954 6107591 complement(1933455..1934201) 1 NC_010519.1 KEGG: hdu:HD0915 hypothetical protein; hypothetical protein 1934201 6107591 HSM_1682 Haemophilus somnus 2336 hypothetical protein YP_001785002.1 1933455 R 228400 CDS YP_001785003.1 170717955 6107592 complement(1934341..1935315) 1 NC_010519.1 PFAM: domain of unknown function DUF1738; KEGG: hso:HS_1780 antirestriction protein; hypothetical protein 1935315 6107592 HSM_1683 Haemophilus somnus 2336 hypothetical protein YP_001785003.1 1934341 R 228400 CDS YP_001785004.1 170717956 6107593 complement(1935560..1935967) 1 NC_010519.1 KEGG: hso:HS_1781 Haemophilus-specific protein, uncharacterized; hypothetical protein 1935967 6107593 HSM_1684 Haemophilus somnus 2336 hypothetical protein YP_001785004.1 1935560 R 228400 CDS YP_001785005.1 170717957 6107594 complement(1936083..1936925) 1 NC_010519.1 hypothetical protein 1936925 6107594 HSM_1685 Haemophilus somnus 2336 hypothetical protein YP_001785005.1 1936083 R 228400 CDS YP_001785006.1 170717958 6107595 complement(1937003..1937398) 1 NC_010519.1 hypothetical protein 1937398 6107595 HSM_1686 Haemophilus somnus 2336 hypothetical protein YP_001785006.1 1937003 R 228400 CDS YP_001785007.1 170717959 6107596 complement(1937497..1937742) 1 NC_010519.1 KEGG: hso:HS_1778 Haemophilus-specific protein, uncharacterized; hypothetical protein 1937742 6107596 HSM_1687 Haemophilus somnus 2336 hypothetical protein YP_001785007.1 1937497 R 228400 CDS YP_001785008.1 170717960 6107597 complement(1937814..1938167) 1 NC_010519.1 KEGG: hit:NTHI0148 hypothetical protein; hypothetical protein 1938167 6107597 HSM_1688 Haemophilus somnus 2336 hypothetical protein YP_001785008.1 1937814 R 228400 CDS YP_001785009.1 170717961 6107598 1938541..1938984 1 NC_010519.1 PFAM: protein of unknown function DUF1525; KEGG: hso:HS_1776 hypothetical protein; hypothetical protein 1938984 6107598 HSM_1689 Haemophilus somnus 2336 hypothetical protein YP_001785009.1 1938541 D 228400 CDS YP_001785010.1 170717963 6107599 1938981..1939922 1 NC_010519.1 PFAM: protein of unknown function DUF1527; KEGG: hso:HS_1775 hypothetical protein; hypothetical protein 1939922 6107599 HSM_1690 Haemophilus somnus 2336 hypothetical protein YP_001785010.1 1938981 D 228400 CDS YP_001785011.1 170717964 6107601 1939940..1941952 1 NC_010519.1 KEGG: hso:HS_1774 hypothetical protein; hypothetical protein 1941952 6107601 HSM_1691 Haemophilus somnus 2336 hypothetical protein YP_001785011.1 1939940 D 228400 CDS YP_001785012.1 170717965 6107602 1941973..1942401 1 NC_010519.1 KEGG: hit:NTHI0144 hypothetical protein; hypothetical protein 1942401 6107602 HSM_1692 Haemophilus somnus 2336 hypothetical protein YP_001785012.1 1941973 D 228400 CDS YP_001785013.1 170717966 6107603 1942617..1943087 1 NC_010519.1 KEGG: spa:M6_Spy0066 unknown phage protein; phage protein 1943087 6107603 HSM_1693 Haemophilus somnus 2336 phage protein YP_001785013.1 1942617 D 228400 CDS YP_001785014.1 170717967 6107604 1943108..1943449 1 NC_010519.1 hypothetical protein 1943449 6107604 HSM_1694 Haemophilus somnus 2336 hypothetical protein YP_001785014.1 1943108 D 228400 CDS YP_001785015.1 170717968 6107605 complement(1943495..1944967) 1 NC_010519.1 KEGG: hit:NTHI0137 conserved membrane protein; hypothetical protein 1944967 6107605 HSM_1695 Haemophilus somnus 2336 hypothetical protein YP_001785015.1 1943495 R 228400 CDS YP_001785016.1 170717969 6107606 complement(1944978..1945295) 1 NC_010519.1 KEGG: hso:HS_1766 Haemophilus-specific protein, uncharacterized; hypothetical protein 1945295 6107606 HSM_1696 Haemophilus somnus 2336 hypothetical protein YP_001785016.1 1944978 R 228400 CDS YP_001785017.1 170717970 6107607 complement(1945285..1945713) 1 NC_010519.1 KEGG: hdu:HD0931 hypothetical protein; hypothetical protein 1945713 6107607 HSM_1697 Haemophilus somnus 2336 hypothetical protein YP_001785017.1 1945285 R 228400 CDS YP_001785018.1 170717971 6107608 complement(1945713..1948550) 1 NC_010519.1 KEGG: hso:HS_1764 hypothetical protein; hypothetical protein 1948550 6107608 HSM_1698 Haemophilus somnus 2336 hypothetical protein YP_001785018.1 1945713 R 228400 CDS YP_001785019.1 170717972 6107609 complement(1948553..1948951) 1 NC_010519.1 KEGG: hso:HS_1763 hypothetical protein; hypothetical protein 1948951 6107609 HSM_1699 Haemophilus somnus 2336 hypothetical protein YP_001785019.1 1948553 R 228400 CDS YP_001785020.1 170717975 6107610 complement(1948964..1950418) 1 NC_010519.1 KEGG: hdu:HD0935 hypothetical protein; hypothetical protein 1950418 6107610 HSM_1700 Haemophilus somnus 2336 hypothetical protein YP_001785020.1 1948964 R 228400 CDS YP_001785021.1 170717976 6107613 complement(1950430..1951314) 1 NC_010519.1 KEGG: hit:NTHI0131 hypothetical protein; hypothetical protein 1951314 6107613 HSM_1701 Haemophilus somnus 2336 hypothetical protein YP_001785021.1 1950430 R 228400 CDS YP_001785022.1 170717977 6107614 complement(1951314..1951958) 1 NC_010519.1 KEGG: hso:HS_1760 hypothetical protein; hypothetical protein 1951958 6107614 HSM_1702 Haemophilus somnus 2336 hypothetical protein YP_001785022.1 1951314 R 228400 CDS YP_001785023.1 170717978 6107615 complement(1951962..1952327) 1 NC_010519.1 KEGG: hso:HS_1759 hypothetical protein; hypothetical protein 1952327 6107615 HSM_1703 Haemophilus somnus 2336 hypothetical protein YP_001785023.1 1951962 R 228400 CDS YP_001785024.1 170717979 6107616 complement(1952350..1952739) 1 NC_010519.1 KEGG: hso:HS_1758 Haemophilus-specific protein, uncharacterized; hypothetical protein 1952739 6107616 HSM_1704 Haemophilus somnus 2336 hypothetical protein YP_001785024.1 1952350 R 228400 CDS YP_001785025.1 170717980 6107617 complement(1952754..1952990) 1 NC_010519.1 KEGG: hso:HS_1757 Haemophilus-specific protein, uncharacterized; hypothetical protein 1952990 6107617 HSM_1705 Haemophilus somnus 2336 hypothetical protein YP_001785025.1 1952754 R 228400 CDS YP_001785026.1 170717981 6107618 complement(1952987..1953313) 1 NC_010519.1 KEGG: hso:HS_1756 hypothetical protein; hypothetical protein 1953313 6107618 HSM_1706 Haemophilus somnus 2336 hypothetical protein YP_001785026.1 1952987 R 228400 CDS YP_001785027.1 170717982 6107619 1953500..1953883 1 NC_010519.1 KEGG: hso:HS_1789 Haemophilus-specific protein, uncharacterized; hypothetical protein 1953883 6107619 HSM_1707 Haemophilus somnus 2336 hypothetical protein YP_001785027.1 1953500 D 228400 CDS YP_001785028.1 170717983 6107620 complement(1953915..1954610) 1 NC_010519.1 KEGG: hit:NTHI0126 conserved membrane protein; hypothetical protein 1954610 6107620 HSM_1708 Haemophilus somnus 2336 hypothetical protein YP_001785028.1 1953915 R 228400 CDS YP_001785029.1 170717984 6107621 complement(1954607..1954960) 1 NC_010519.1 KEGG: hso:HS_1752 Haemophilus-specific protein, uncharacterized; hypothetical protein 1954960 6107621 HSM_1709 Haemophilus somnus 2336 hypothetical protein YP_001785029.1 1954607 R 228400 CDS YP_001785030.1 170717986 6107622 complement(1954953..1957154) 1 NC_010519.1 KEGG: hso:HS_1751 hypothetical protein; hypothetical protein 1957154 6107622 HSM_1710 Haemophilus somnus 2336 hypothetical protein YP_001785030.1 1954953 R 228400 CDS YP_001785031.1 170717987 6107624 complement(1957154..1957660) 1 NC_010519.1 KEGG: hso:HS_1750 hypothetical protein; hypothetical protein 1957660 6107624 HSM_1711 Haemophilus somnus 2336 hypothetical protein YP_001785031.1 1957154 R 228400 CDS YP_001785032.1 170717988 6107625 complement(1957663..1958433) 1 NC_010519.1 KEGG: hit:NTHI0122 conserved exported protein; hypothetical protein 1958433 6107625 HSM_1712 Haemophilus somnus 2336 hypothetical protein YP_001785032.1 1957663 R 228400 CDS YP_001785033.1 170717989 6107626 complement(1958412..1959185) 1 NC_010519.1 KEGG: hso:HS_1747 hypothetical protein; hypothetical protein 1959185 6107626 HSM_1713 Haemophilus somnus 2336 hypothetical protein YP_001785033.1 1958412 R 228400 CDS YP_001785034.1 170717990 6107627 complement(1959185..1959814) 1 NC_010519.1 KEGG: hit:NTHI0120 conserved lipoprotein; lipoprotein 1959814 6107627 HSM_1714 Haemophilus somnus 2336 lipoprotein YP_001785034.1 1959185 R 228400 CDS YP_001785035.1 170717991 6107628 complement(1959973..1960233) 1 NC_010519.1 KEGG: pau:PA14_59530 hypothetical protein; hypothetical protein 1960233 6107628 HSM_1715 Haemophilus somnus 2336 hypothetical protein YP_001785035.1 1959973 R 228400 CDS YP_001785036.1 170717992 6107629 complement(1960346..1960708) 1 NC_010519.1 KEGG: hso:HS_1744 Haemophilus-specific protein, uncharacterized; hypothetical protein 1960708 6107629 HSM_1716 Haemophilus somnus 2336 hypothetical protein YP_001785036.1 1960346 R 228400 CDS YP_001785037.1 170717993 6107630 complement(1960788..1961195) 1 NC_010519.1 KEGG: hso:HS_1739 hypothetical protein; hypothetical protein 1961195 6107630 HSM_1717 Haemophilus somnus 2336 hypothetical protein YP_001785037.1 1960788 R 228400 CDS YP_001785038.1 170717994 6107631 complement(1961221..1961901) 1 NC_010519.1 hypothetical protein 1961901 6107631 HSM_1718 Haemophilus somnus 2336 hypothetical protein YP_001785038.1 1961221 R 228400 CDS YP_001785039.1 170717995 6107632 complement(1962007..1962438) 1 NC_010519.1 KEGG: hso:HS_1738 hypothetical protein; hypothetical protein 1962438 6107632 HSM_1719 Haemophilus somnus 2336 hypothetical protein YP_001785039.1 1962007 R 228400 CDS YP_001785040.1 170717997 6107633 complement(1963256..1965307) 1 NC_010519.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 1965307 6107633 HSM_1720 Haemophilus somnus 2336 DNA topoisomerase III YP_001785040.1 1963256 R 228400 CDS YP_001785041.1 170717998 6107635 complement(1965467..1965985) 1 NC_010519.1 KEGG: hso:HS_1732 Haemophilus-specific protein, uncharacterized; hypothetical protein 1965985 6107635 HSM_1721 Haemophilus somnus 2336 hypothetical protein YP_001785041.1 1965467 R 228400 CDS YP_001785042.1 170717999 6107636 1966462..1967172 1 NC_010519.1 KEGG: hso:HS_1735 Haemophilus-specific protein, uncharacterized; hypothetical protein 1967172 6107636 HSM_1722 Haemophilus somnus 2336 hypothetical protein YP_001785042.1 1966462 D 228400 CDS YP_001785043.1 170718000 6107637 complement(1967711..1968478) 1 NC_010519.1 PFAM: aldo/keto reductase; KEGG: ade:Adeh_3215 aldo/keto reductase; aldo/keto reductase 1968478 6107637 HSM_1723 Haemophilus somnus 2336 aldo/keto reductase YP_001785043.1 1967711 R 228400 CDS YP_001785044.1 170718001 6107638 1968477..1968797 1 NC_010519.1 hypothetical protein 1968797 6107638 HSM_1724 Haemophilus somnus 2336 hypothetical protein YP_001785044.1 1968477 D 228400 CDS YP_001785045.1 170718002 6107639 1968979..1969434 1 NC_010519.1 PFAM: protein of unknown function DUF411; KEGG: pmu:PM1939 hypothetical S.typhimurium; hypothetical protein 1969434 6107639 HSM_1725 Haemophilus somnus 2336 hypothetical protein YP_001785045.1 1968979 D 228400 CDS YP_001785046.1 170718003 6107640 1969449..1970996 1 NC_010519.1 PFAM: multicopper oxidase type 1; multicopper oxidase type 2; multicopper oxidase type 3; KEGG: pmu:PM1938 hypothetical E.coli; multicopper oxidase type 3 1970996 6107640 HSM_1726 Haemophilus somnus 2336 multicopper oxidase type 3 YP_001785046.1 1969449 D 228400 CDS YP_001785047.1 170718004 6107641 complement(1971086..1971241) 1 NC_010519.1 KEGG: bam:Bamb_5387 alcohol dehydrogenase, zinc-binding domain protein; alcohol dehydrogenase 1971241 6107641 HSM_1727 Haemophilus somnus 2336 alcohol dehydrogenase YP_001785047.1 1971086 R 228400 CDS YP_001785048.1 170718005 6107642 1971664..1972068 1 NC_010519.1 TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; KEGG: hit:NTHI0403 probable heavy metal dependent transcriptional regulator; MerR family transcriptional regulator 1972068 6107642 HSM_1728 Haemophilus somnus 2336 MerR family transcriptional regulator YP_001785048.1 1971664 D 228400 CDS YP_001785049.1 170718006 6107643 complement(1972283..1972600) 1 NC_010519.1 PFAM: protein of unknown function DUF411; KEGG: pmu:PM1939 hypothetical S.typhimurium; hypothetical protein 1972600 6107643 HSM_1729 Haemophilus somnus 2336 hypothetical protein YP_001785049.1 1972283 R 228400 CDS YP_001785050.1 170718008 6107644 complement(1972853..1974457) 1 NC_010519.1 PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: pmu:PM1938 hypothetical E.coli; multicopper oxidase type 3 1974457 6107644 HSM_1730 Haemophilus somnus 2336 multicopper oxidase type 3 YP_001785050.1 1972853 R 228400 CDS YP_001785051.1 170718009 6107646 complement(1974826..1977018) 1 NC_010519.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: haloacid dehalogenase; E1-E2 ATPase-associated domain protein; KEGG: neu:NE1216 haloacid dehalogenase/epoxide hydrolase family:E1-E2 ATPase; ATPase P 1977018 6107646 HSM_1731 Haemophilus somnus 2336 ATPase P YP_001785051.1 1974826 R 228400 CDS YP_001785052.1 170718010 6107647 complement(1977326..1978072) 1 NC_010519.1 PFAM: protein of unknown function DUF305; KEGG: par:Psyc_0285 hypothetical protein; hypothetical protein 1978072 6107647 HSM_1732 Haemophilus somnus 2336 hypothetical protein YP_001785052.1 1977326 R 228400 CDS YP_001785053.1 170718011 6107648 1978360..1978878 1 NC_010519.1 KEGG: ret:RHE_PF00025 hypothetical protein; hypothetical protein 1978878 6107648 HSM_1733 Haemophilus somnus 2336 hypothetical protein YP_001785053.1 1978360 D 228400 CDS YP_001785054.1 170718012 6107649 complement(1978881..1979504) 1 NC_010519.1 PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: sty:HCM1.243 tetracycline repressor protein; TetR family transcriptional regulator 1979504 6107649 HSM_1734 Haemophilus somnus 2336 TetR family transcriptional regulator YP_001785054.1 1978881 R 228400 CDS YP_001785055.1 170718013 6107650 1979596..1980798 1 NC_010519.1 PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: sty:HCM1.241c tetracycline resistance protein; major facilitator transporter 1980798 6107650 HSM_1735 Haemophilus somnus 2336 major facilitator transporter YP_001785055.1 1979596 D 228400 CDS YP_001785056.1 170718014 6107651 complement(1980899..1981231) 1 NC_010519.1 PFAM: small multidrug resistance protein; KEGG: nme:NMB0393 multidrug resistance protein; small multidrug resistance protein 1981231 6107651 HSM_1736 Haemophilus somnus 2336 small multidrug resistance protein YP_001785056.1 1980899 R 228400 CDS YP_001785057.1 170718015 6107652 complement(1981270..1981719) 1 NC_010519.1 PFAM: regulatory protein MarR; KEGG: msu:MS2146 MarR protein; MarR family transcriptional regulator 1981719 6107652 HSM_1737 Haemophilus somnus 2336 MarR family transcriptional regulator YP_001785057.1 1981270 R 228400 CDS YP_001785058.1 170718016 6107653 complement(1981742..1982113) 1 NC_010519.1 PFAM: protein of unknown function DUF1304; KEGG: nmc:NMC0467 hypothetical protein; hypothetical protein 1982113 6107653 HSM_1738 Haemophilus somnus 2336 hypothetical protein YP_001785058.1 1981742 R 228400 CDS YP_001785059.1 170718017 6107654 complement(1982332..1983432) 1 NC_010519.1 KEGG: msu:MS2120 hypothetical protein; hypothetical protein 1983432 6107654 HSM_1739 Haemophilus somnus 2336 hypothetical protein YP_001785059.1 1982332 R 228400 CDS YP_001785060.1 170718019 6107655 complement(1983604..1984218) 1 NC_010519.1 PFAM: cation efflux protein; KEGG: pmu:PM1942 unknown; cation efflux protein 1984218 6107655 HSM_1740 Haemophilus somnus 2336 cation efflux protein YP_001785060.1 1983604 R 228400 CDS YP_001785061.1 170718020 6107657 1984290..1984688 1 NC_010519.1 PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; KEGG: pmu:PM1941 transcriptional regulator, merR family; MerR family transcriptional regulator 1984688 6107657 HSM_1741 Haemophilus somnus 2336 MerR family transcriptional regulator YP_001785061.1 1984290 D 228400 CDS YP_001785062.1 170718021 6107658 1984727..1984873 1 NC_010519.1 KEGG: pmu:PM1943 hypothetical Synechocystis sp.; hypothetical protein 1984873 6107658 HSM_1742 Haemophilus somnus 2336 hypothetical protein YP_001785062.1 1984727 D 228400 CDS YP_001785063.1 170718022 6107659 1984910..1985062 1 NC_010519.1 KEGG: pmu:PM1943 hypothetical Synechocystis sp.; hypothetical protein 1985062 6107659 HSM_1743 Haemophilus somnus 2336 hypothetical protein YP_001785063.1 1984910 D 228400 CDS YP_001785064.1 170718023 6107660 complement(1985115..1985723) 1 NC_010519.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; KEGG: pmu:PM1940 quinone reductase homolog; alcohol dehydrogenase 1985723 6107660 HSM_1744 Haemophilus somnus 2336 alcohol dehydrogenase YP_001785064.1 1985115 R 228400 CDS YP_001785065.1 170718024 6107661 complement(1986316..1986768) 1 NC_010519.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: hso:HS_1729 single-stranded DNA binding protein; single-strand binding protein 1986768 6107661 HSM_1745 Haemophilus somnus 2336 single-strand binding protein YP_001785065.1 1986316 R 228400 CDS YP_001785066.1 170718025 6107662 complement(1987102..1987587) 1 NC_010519.1 KEGG: hit:NTHI0108 hypothetical protein; hypothetical protein 1987587 6107662 HSM_1746 Haemophilus somnus 2336 hypothetical protein YP_001785066.1 1987102 R 228400 CDS YP_001785067.1 170718026 6107663 complement(1987596..1988354) 1 NC_010519.1 KEGG: hit:NTHI0107 hypothetical protein; hypothetical protein 1988354 6107663 HSM_1747 Haemophilus somnus 2336 hypothetical protein YP_001785067.1 1987596 R 228400 CDS YP_001785068.1 170718027 6107664 complement(1988533..1989723) 1 NC_010519.1 KEGG: hit:NTHI0106 hypothetical protein; hypothetical protein 1989723 6107664 HSM_1748 Haemophilus somnus 2336 hypothetical protein YP_001785068.1 1988533 R 228400 CDS YP_001785069.1 170718028 6107665 complement(1989882..1990439) 1 NC_010519.1 KEGG: hdu:HD0969 hypothetical protein; hypothetical protein 1990439 6107665 HSM_1749 Haemophilus somnus 2336 hypothetical protein YP_001785069.1 1989882 R 228400 CDS YP_001785070.1 170718030 6107666 complement(1990432..1992078) 1 NC_010519.1 KEGG: hit:NTHI0103 hypothetical protein; hypothetical protein 1992078 6107666 HSM_1750 Haemophilus somnus 2336 hypothetical protein YP_001785070.1 1990432 R 228400 CDS YP_001785071.1 170718031 6107668 complement(1992087..1993448) 1 NC_010519.1 TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase; SMART: ATPase AAA; KEGG: hit:NTHI0102 replicative DNA helicase; replicative DNA helicase 1993448 6107668 HSM_1751 Haemophilus somnus 2336 replicative DNA helicase YP_001785071.1 1992087 R 228400 CDS YP_001785072.1 170718032 6107669 complement(1993460..1994284) 1 NC_010519.1 KEGG: hit:NTHI0101 predicted ATPase involved in chromosome partitioning; chromosome partitioning ATPase 1994284 6107669 HSM_1752 Haemophilus somnus 2336 chromosome partitioning ATPase YP_001785072.1 1993460 R 228400 CDS YP_001785073.1 170718033 6108896 complement(1994707..1995777) 1 NC_010519.1 PFAM: permease YjgP/YjgQ family protein; KEGG: hso:HS_0518 conserved permease; YjgP/YjgQ family permease 1995777 6108896 HSM_1753 Haemophilus somnus 2336 YjgP/YjgQ family permease YP_001785073.1 1994707 R 228400 CDS YP_001785074.1 170718034 6107671 complement(1995790..1996893) 1 NC_010519.1 PFAM: permease YjgP/YjgQ family protein; KEGG: hso:HS_0517 conserved permease; YjgP/YjgQ family permease 1996893 6107671 HSM_1754 Haemophilus somnus 2336 YjgP/YjgQ family permease YP_001785074.1 1995790 R 228400 CDS YP_001785075.1 170718035 6107672 1997012..1998499 1 NC_010519.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 1998499 6107672 HSM_1755 Haemophilus somnus 2336 leucyl aminopeptidase YP_001785075.1 1997012 D 228400 CDS YP_001785076.1 170718036 6107673 1998772..1999530 1 NC_010519.1 PFAM: regulatory protein GntR HTH; regulatory protein DeoR; hypothetical protein; regulatory protein DeoR; KEGG: hso:HS_0515 glycerol-3-phosphate regulon repressor (glp operon repressor); DeoR family transcriptional regulator 1999530 6107673 HSM_1756 Haemophilus somnus 2336 DeoR family transcriptional regulator YP_001785076.1 1998772 D 228400 CDS YP_001785077.1 170718037 6107674 complement(1999580..2000851) 1 NC_010519.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2000851 glpC 6107674 glpC Haemophilus somnus 2336 sn-glycerol-3-phosphate dehydrogenase subunit C YP_001785077.1 1999580 R 228400 CDS YP_001785078.1 170718038 6107675 complement(2000862..2002166) 1 NC_010519.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2002166 6107675 HSM_1758 Haemophilus somnus 2336 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_001785078.1 2000862 R 228400 CDS YP_001785079.1 170718039 6107676 complement(2002150..2003838) 1 NC_010519.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2003838 glpA 6107676 glpA Haemophilus somnus 2336 sn-glycerol-3-phosphate dehydrogenase subunit A YP_001785079.1 2002150 R 228400 CDS YP_001785080.1 170718041 6107677 2004164..2005609 1 NC_010519.1 TIGRFAM: phosphoglycerate transporter; glycerol-3-phosphate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_0511 glycerol 3-phosphate transporter; glycerol-3-phosphate transporter 2005609 6107677 HSM_1760 Haemophilus somnus 2336 glycerol-3-phosphate transporter YP_001785080.1 2004164 D 228400 CDS YP_001785081.1 170718042 6107679 2005723..2006808 1 NC_010519.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 2006808 glpQ 6107679 glpQ Haemophilus somnus 2336 glycerophosphodiester phosphodiesterase YP_001785081.1 2005723 D 228400 CDS YP_001785082.1 170718043 6107680 complement(2006888..2007487) 1 NC_010519.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 2007487 ruvC 6107680 ruvC Haemophilus somnus 2336 Holliday junction resolvase YP_001785082.1 2006888 R 228400 CDS YP_001785083.1 170718044 6107681 complement(2007616..2008356) 1 NC_010519.1 PFAM: protein of unknown function DUF28; KEGG: hso:HS_0508 hypothetical protein; hypothetical protein 2008356 6107681 HSM_1763 Haemophilus somnus 2336 hypothetical protein YP_001785083.1 2007616 R 228400 CDS YP_001785084.1 170718045 6107682 complement(2008358..2008810) 1 NC_010519.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 2008810 ntpA 6107682 ntpA Haemophilus somnus 2336 dATP pyrophosphohydrolase YP_001785084.1 2008358 R 228400 CDS YP_001785085.1 170718046 6107683 complement(2008964..2009296) 1 NC_010519.1 PFAM: protein of unknown function UPF0125; KEGG: hso:HS_0506 hypothetical protein; hypothetical protein 2009296 6107683 HSM_1765 Haemophilus somnus 2336 hypothetical protein YP_001785085.1 2008964 R 228400 CDS YP_001785086.1 170718047 6107684 complement(2009289..2009852) 1 NC_010519.1 PFAM: cyclase/dehydrase; KEGG: hso:HS_0505 hypothetical protein; cyclase/dehydrase 2009852 6107684 HSM_1766 Haemophilus somnus 2336 cyclase/dehydrase YP_001785086.1 2009289 R 228400 CDS YP_001785087.1 170718048 6107685 2009901..2010485 1 NC_010519.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 2010485 6107685 HSM_1767 Haemophilus somnus 2336 peptidyl-tRNA hydrolase YP_001785087.1 2009901 D 228400 CDS YP_001785088.1 170718049 6107686 2010552..2011643 1 NC_010519.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 2011643 6107686 HSM_1768 Haemophilus somnus 2336 GTP-dependent nucleic acid-binding protein EngD YP_001785088.1 2010552 D 228400 CDS YP_001785089.1 170718050 6107687 2011893..2012303 1 NC_010519.1 TIGRFAM: lactoylglutathione lyase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: hso:HS_0502 lactoylglutathione lyase (glyoxalase I); lactoylglutathione lyase 2012303 6107687 HSM_1769 Haemophilus somnus 2336 lactoylglutathione lyase YP_001785089.1 2011893 D 228400 CDS YP_001785090.1 170718052 6107688 2012391..2013047 1 NC_010519.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 2013047 6107688 HSM_1770 Haemophilus somnus 2336 ribonuclease T YP_001785090.1 2012391 D 228400 CDS YP_001785091.1 170718053 6107690 complement(2013097..2014500) 1 NC_010519.1 PFAM: multicopper oxidase type 3; KEGG: hso:HS_0500 suppressor of FtsI; multicopper oxidase type 3 2014500 6107690 HSM_1771 Haemophilus somnus 2336 multicopper oxidase type 3 YP_001785091.1 2013097 R 228400 CDS YP_001785092.1 170718054 6107691 complement(2014516..2015241) 1 NC_010519.1 TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; KEGG: hso:HS_0499 1-acylglycerol-3-phosphate O-acyltransferase (1-acyl-sn-glycerol-3-phosphate acyltransferase); 1-acyl-sn-glycerol-3-phosphate acyltransferase 2015241 6107691 HSM_1772 Haemophilus somnus 2336 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_001785092.1 2014516 R 228400 CDS YP_001785093.1 170718055 6107692 2015352..2016056 1 NC_010519.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 2016056 6107692 HSM_1773 Haemophilus somnus 2336 UDP-2,3-diacylglucosamine hydrolase YP_001785093.1 2015352 D 228400 CDS YP_001785094.1 170718056 6107693 complement(2016122..2018302) 1 NC_010519.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 2018302 uvrD 6107693 uvrD Haemophilus somnus 2336 DNA-dependent helicase II YP_001785094.1 2016122 R 228400 CDS YP_001785095.1 170718057 6107694 complement(2018450..2019535) 1 NC_010519.1 KEGG: hso:HS_0496 conserved hypothetical protein; RNA 2'-O-ribose methyltransferase 2019535 6107694 HSM_1775 Haemophilus somnus 2336 RNA 2'-O-ribose methyltransferase YP_001785095.1 2018450 R 228400 CDS YP_001785096.1 170718058 6107695 complement(2019528..2020421) 1 NC_010519.1 glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 2020421 6107695 HSM_1776 Haemophilus somnus 2336 DNA-binding transcriptional activator GcvA YP_001785096.1 2019528 R 228400 CDS YP_001785097.1 170718059 6107696 2020874..2021893 1 NC_010519.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 2021893 6107696 HSM_1777 Haemophilus somnus 2336 branched-chain amino acid aminotransferase YP_001785097.1 2020874 D 228400 CDS YP_001785098.1 170718060 6107697 complement(2021974..2022450) 1 NC_010519.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2022450 bcp 6107697 bcp Haemophilus somnus 2336 thioredoxin-dependent thiol peroxidase YP_001785098.1 2021974 R 228400 CDS YP_001785099.1 170718061 6107698 2022560..2023456 1 NC_010519.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 2023456 6107698 HSM_1779 Haemophilus somnus 2336 dihydrodipicolinate synthase YP_001785099.1 2022560 D 228400 CDS YP_001785100.1 170718063 6107699 2023759..2024355 1 NC_010519.1 KEGG: hso:HS_0337 hypothetical protein; hypothetical protein 2024355 6107699 HSM_1780 Haemophilus somnus 2336 hypothetical protein YP_001785100.1 2023759 D 228400 CDS YP_001785101.1 170718064 6107701 complement(2024470..2024916) 1 NC_010519.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 2024916 rimI 6107701 rimI Haemophilus somnus 2336 ribosomal-protein-alanine N-acetyltransferase YP_001785101.1 2024470 R 228400 CDS YP_001785102.1 170718065 6107702 complement(2024920..2025324) 1 NC_010519.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 2025324 6107702 HSM_1782 Haemophilus somnus 2336 DNA polymerase III subunit psi YP_001785102.1 2024920 R 228400 CDS YP_001785103.1 170718066 6107703 complement(2025502..2027913) 1 NC_010519.1 KEGG: hso:HS_0489 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16; ATPase AAA central domain protein; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; ATP-dependent protease La 2027913 6107703 HSM_1783 Haemophilus somnus 2336 ATP-dependent protease La YP_001785103.1 2025502 R 228400 CDS YP_001785104.1 170718067 6107704 complement(2028202..2029089) 1 NC_010519.1 TIGRFAM: HflC protein; PFAM: hypothetical protein; KEGG: hso:HS_0488 HflC protein; HflC protein 2029089 6107704 HSM_1784 Haemophilus somnus 2336 HflC protein YP_001785104.1 2028202 R 228400 CDS YP_001785105.1 170718068 6107705 complement(2029089..2030339) 1 NC_010519.1 TIGRFAM: HflK protein; PFAM: hypothetical protein; KEGG: hso:HS_0487 HflK protein; HflK protein 2030339 6107705 HSM_1785 Haemophilus somnus 2336 HflK protein YP_001785105.1 2029089 R 228400 CDS YP_001785106.1 170718069 6107706 complement(2030648..2031613) 1 NC_010519.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 2031613 6107706 HSM_1786 Haemophilus somnus 2336 6-phosphofructokinase YP_001785106.1 2030648 R 228400 CDS YP_001785107.1 170718070 6107707 complement(2031726..2032622) 1 NC_010519.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: hso:HS_0484 cation efflux protein; cation diffusion facilitator family transporter 2032622 6107707 HSM_1787 Haemophilus somnus 2336 cation diffusion facilitator family transporter YP_001785107.1 2031726 R 228400 CDS YP_001785108.1 170718071 6107708 complement(2032637..2033191) 1 NC_010519.1 KEGG: hso:HS_0483 hypothetical protein; hypothetical protein 2033191 6107708 HSM_1788 Haemophilus somnus 2336 hypothetical protein YP_001785108.1 2032637 R 228400 CDS YP_001785109.1 170718072 6107709 complement(2033188..2033964) 1 NC_010519.1 PFAM: protein of unknown function DUF328; KEGG: hso:HS_0482 hypothetical protein; hypothetical protein 2033964 6107709 HSM_1789 Haemophilus somnus 2336 hypothetical protein YP_001785109.1 2033188 R 228400 CDS YP_001785110.1 170718074 6107710 complement(2033980..2034651) 1 NC_010519.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2034651 6107710 HSM_1790 Haemophilus somnus 2336 uracil-DNA glycosylase YP_001785110.1 2033980 R 228400 CDS YP_001785111.1 170718075 6107712 2034911..2035294 1 NC_010519.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 2035294 6107712 HSM_1791 Haemophilus somnus 2336 autonomous glycyl radical cofactor GrcA YP_001785111.1 2034911 D 228400 CDS YP_001785112.1 170718076 6107713 complement(2035397..2037463) 1 NC_010519.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 2037463 glyS 6107713 glyS Haemophilus somnus 2336 glycyl-tRNA synthetase subunit beta YP_001785112.1 2035397 R 228400 CDS YP_001785113.1 170718077 6107714 2038316..2046592 1 NC_010519.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1058 large adhesin; YadA domain-containing protein 2046592 6107714 HSM_1793 Haemophilus somnus 2336 YadA domain-containing protein YP_001785113.1 2038316 D 228400 CDS YP_001785114.1 170718078 6107715 2047245..2048180 1 NC_010519.1 PFAM: glycosyltransferase family 52; KEGG: pmu:PM0508 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 3-sialyltransfera se; glycosyl transferase family protein 2048180 6107715 HSM_1794 Haemophilus somnus 2336 glycosyl transferase family protein YP_001785114.1 2047245 D 228400 CDS YP_001785115.1 170718079 6107716 complement(2048250..2048540) 1 NC_010519.1 KEGG: hso:HS_1633 conserved hypothetical protein; hypothetical protein 2048540 6107716 HSM_1795 Haemophilus somnus 2336 hypothetical protein YP_001785115.1 2048250 R 228400 CDS YP_001785116.1 170718080 6107717 complement(2048552..2048914) 1 NC_010519.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 2048914 6107717 HSM_1796 Haemophilus somnus 2336 sulfur relay protein TusC YP_001785116.1 2048552 R 228400 CDS YP_001785117.1 170718081 6107718 complement(2048911..2049291) 1 NC_010519.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 2049291 6107718 HSM_1797 Haemophilus somnus 2336 sulfur transfer complex subunit TusD YP_001785117.1 2048911 R 228400 CDS YP_001785118.1 170718082 6107719 complement(2049291..2049959) 1 NC_010519.1 PFAM: YheO domain protein; KEGG: hso:HS_1636 hypothetical protein; YheO domain-containing protein 2049959 6107719 HSM_1798 Haemophilus somnus 2336 YheO domain-containing protein YP_001785118.1 2049291 R 228400 CDS YP_001785119.1 170718083 6107720 complement(2050028..2050714) 1 NC_010519.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: hso:HS_1637 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase); FKBP-type peptidylprolyl isomerase 2050714 6107720 HSM_1799 Haemophilus somnus 2336 FKBP-type peptidylprolyl isomerase YP_001785119.1 2050028 R 228400 CDS YP_001785120.1 170718086 6107721 2050811..2051032 1 NC_010519.1 PFAM: SlyX family protein; KEGG: hso:HS_1638 SlyX family protein; hypothetical protein 2051032 6107721 HSM_1800 Haemophilus somnus 2336 hypothetical protein YP_001785120.1 2050811 D 228400 CDS YP_001785121.1 170718087 6107724 complement(2051034..2051489) 1 NC_010519.1 PFAM: NUDIX hydrolase; KEGG: hso:HS_1639 NTP pyrophosphohydrolase, MutT/NUDIX family; NUDIX hydrolase 2051489 6107724 HSM_1801 Haemophilus somnus 2336 NUDIX hydrolase YP_001785121.1 2051034 R 228400 CDS YP_001785122.1 170718088 6107725 complement(2051491..2052174) 1 NC_010519.1 PFAM: pseudouridine synthase; KEGG: hso:HS_1640 ribosomal large subunit pseudouridine synthase; pseudouridine synthase 2052174 6107725 HSM_1802 Haemophilus somnus 2336 pseudouridine synthase YP_001785122.1 2051491 R 228400 CDS YP_001785123.1 170718089 6107726 complement(2052225..2054438) 1 NC_010519.1 TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate dehydrogenase NADP-dependent monomeric type; KEGG: hso:HS_1641 isocitrate dehydrogenase; isocitrate dehydrogenase 2054438 6107726 HSM_1803 Haemophilus somnus 2336 isocitrate dehydrogenase YP_001785123.1 2052225 R 228400 CDS YP_001785124.1 170718090 6107727 2054653..2055831 1 NC_010519.1 PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; KEGG: hso:HS_1642 hypothetical protein; ATP-dependent carboxylate-amine ligase domain-containing protein 2055831 6107727 HSM_1804 Haemophilus somnus 2336 ATP-dependent carboxylate-amine ligase domain-containing protein YP_001785124.1 2054653 D 228400 CDS YP_001785125.1 170718091 6107728 2055892..2056644 1 NC_010519.1 PFAM: esterase; KEGG: hso:HS_1643 hypothetical protein; esterase 2056644 6107728 HSM_1805 Haemophilus somnus 2336 esterase YP_001785125.1 2055892 D 228400 CDS YP_001785126.1 170718092 6107729 complement(2057099..2058283) 1 NC_010519.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 2058283 6107729 HSM_1806 Haemophilus somnus 2336 elongation factor Tu YP_001785126.1 2057099 R 228400 CDS YP_001785127.1 170718093 6107730 complement(2058355..2060457) 1 NC_010519.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 2060457 6107730 HSM_1807 Haemophilus somnus 2336 elongation factor G YP_001785127.1 2058355 R 228400 CDS YP_001785128.1 170718094 6107731 complement(2060547..2061017) 1 NC_010519.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 2061017 6107731 HSM_1808 Haemophilus somnus 2336 30S ribosomal protein S7 YP_001785128.1 2060547 R 228400 CDS YP_001785129.1 170718095 6107732 complement(2061148..2061522) 1 NC_010519.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 2061522 rpsL 6107732 rpsL Haemophilus somnus 2336 30S ribosomal protein S12 YP_001785129.1 2061148 R 228400 CDS YP_001785130.1 170718097 6107733 complement(2061681..2062541) 1 NC_010519.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2062541 hslO 6107733 hslO Haemophilus somnus 2336 Hsp33-like chaperonin YP_001785130.1 2061681 R 228400 CDS YP_001785131.1 170718098 6107735 complement(2062597..2063007) 1 NC_010519.1 PFAM: RNA-binding S4 domain protein; KEGG: hso:HS_1649 heat shock protein 15; RNA-binding S4 domain-containing protein 2063007 6107735 HSM_1811 Haemophilus somnus 2336 RNA-binding S4 domain-containing protein YP_001785131.1 2062597 R 228400 CDS YP_001785132.1 170718099 6107736 2063079..2063897 1 NC_010519.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: hso:HS_1650 3'-phosphoadenosine 5'-phosphosulfate (PapS) 3'-phosphatase; 3'(2'),5'-bisphosphate nucleotidase 2063897 6107736 HSM_1812 Haemophilus somnus 2336 3'(2'),5'-bisphosphate nucleotidase YP_001785132.1 2063079 D 228400 CDS YP_001785133.1 170718100 6107737 2063897..2065459 1 NC_010519.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2065459 6107737 HSM_1813 Haemophilus somnus 2336 glucose-6-phosphate 1-dehydrogenase YP_001785133.1 2063897 D 228400 CDS YP_001785134.1 170718101 6107738 2065510..2066214 1 NC_010519.1 TIGRFAM: 6-phosphogluconolactonase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: hso:HS_1652 6-phosphogluconolactonase; 6-phosphogluconolactonase 2066214 6107738 HSM_1814 Haemophilus somnus 2336 6-phosphogluconolactonase YP_001785134.1 2065510 D 228400 CDS YP_001785135.1 170718102 6107739 2066247..2066675 1 NC_010519.1 KEGG: hso:HS_1653 hypothetical protein; hypothetical protein 2066675 6107739 HSM_1815 Haemophilus somnus 2336 hypothetical protein YP_001785135.1 2066247 D 228400 CDS YP_001785136.1 170718103 6107740 2066679..2068133 1 NC_010519.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2068133 6107740 HSM_1816 Haemophilus somnus 2336 6-phosphogluconate dehydrogenase YP_001785136.1 2066679 D 228400 CDS YP_001785137.1 170718104 6107741 2068302..2069051 1 NC_010519.1 PFAM: VacJ family lipoprotein; KEGG: hso:HS_1655 VacJ lipoprotein; VacJ family lipoprotein 2069051 6107741 HSM_1817 Haemophilus somnus 2336 VacJ family lipoprotein YP_001785137.1 2068302 D 228400 CDS YP_001785138.1 170718105 6107742 2069071..2069565 1 NC_010519.1 PFAM: YfbU family protein; KEGG: hso:HS_1656 hypothetical protein; hypothetical protein 2069565 6107742 HSM_1818 Haemophilus somnus 2336 hypothetical protein YP_001785138.1 2069071 D 228400 CDS YP_001785139.1 170718106 6107743 complement(2069615..2069914) 1 NC_010519.1 PFAM: protein of unknown function DUF167; KEGG: hso:HS_1657 conserved hypothetical protein; hypothetical protein 2069914 6107743 HSM_1819 Haemophilus somnus 2336 hypothetical protein YP_001785139.1 2069615 R 228400 CDS YP_001785140.1 170718108 6107744 complement(2069940..2070497) 1 NC_010519.1 PFAM: protein of unknown function YGGT; KEGG: hso:HS_1658 conserved hypothetical protein; hypothetical protein 2070497 6107744 HSM_1820 Haemophilus somnus 2336 hypothetical protein YP_001785140.1 2069940 R 228400 CDS YP_001785141.1 170718109 6107746 complement(2070497..2071447) 1 NC_010519.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 2071447 6107746 HSM_1821 Haemophilus somnus 2336 magnesium/nickel/cobalt transporter CorA YP_001785141.1 2070497 R 228400 CDS YP_001785142.1 170718110 6107747 complement(2071781..2072119) 1 NC_010519.1 PFAM: protein of unknown function DUF469; KEGG: hso:HS_1661 hypothetical protein; hypothetical protein 2072119 6107747 HSM_1822 Haemophilus somnus 2336 hypothetical protein YP_001785142.1 2071781 R 228400 CDS YP_001785143.1 170718111 6107748 complement(2072217..2073101) 1 NC_010519.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: hso:HS_1662 transcription regulator, LysR family; LysR family transcriptional regulator 2073101 6107748 HSM_1823 Haemophilus somnus 2336 LysR family transcriptional regulator YP_001785143.1 2072217 R 228400 CDS YP_001785144.1 170718112 6107750 2074705..2075304 1 NC_010519.1 PFAM: phosphoglycerate mutase; KEGG: hso:HS_1664 phosphoglycerate mutase; phosphoglycerate mutase 2075304 6107750 HSM_1826 Haemophilus somnus 2336 phosphoglycerate mutase YP_001785144.1 2074705 D 228400 CDS YP_001785145.1 170718113 6107751 complement(2075444..2075893) 1 NC_010519.1 PFAM: protein of unknown function DUF302; KEGG: hso:HS_1665 hypothetical protein; hypothetical protein 2075893 6107751 HSM_1827 Haemophilus somnus 2336 hypothetical protein YP_001785145.1 2075444 R 228400 CDS YP_001785146.1 170718114 6107752 complement(2075905..2076660) 1 NC_010519.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 2076660 trmB 6107752 trmB Haemophilus somnus 2336 tRNA (guanine-N(7)-)-methyltransferase YP_001785146.1 2075905 R 228400 CDS YP_001785147.1 170718115 6107753 2076806..2077918 1 NC_010519.1 TIGRFAM: A/G-specific adenine glycosylase; PFAM: HhH-GPD family protein; KEGG: hso:HS_1667 A/G-specific adenine glycosylase; A/G-specific adenine glycosylase 2077918 6107753 HSM_1829 Haemophilus somnus 2336 A/G-specific adenine glycosylase YP_001785147.1 2076806 D 228400 CDS YP_001785148.1 170718117 6107754 2077921..2078196 1 NC_010519.1 PFAM: Fe(II) trafficking protein YggX; KEGG: hso:HS_1668 hypothetical protein; hypothetical protein 2078196 6107754 HSM_1830 Haemophilus somnus 2336 hypothetical protein YP_001785148.1 2077921 D 228400 CDS YP_001785149.1 170718118 6107756 2078203..2079294 1 NC_010519.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 2079294 mltC 6107756 mltC Haemophilus somnus 2336 murein transglycosylase C YP_001785149.1 2078203 D 228400 CDS YP_001785150.1 170718119 6107757 2079389..2081044 1 NC_010519.1 PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: hso:HS_1670 phosphomannomutase; phosphoglucomutase/phosphomannomutase subunit alpha/beta 2081044 6107757 HSM_1832 Haemophilus somnus 2336 phosphoglucomutase/phosphomannomutase subunit alpha/beta YP_001785150.1 2079389 D 228400 CDS YP_001785151.1 170718120 6107758 complement(2081173..2082654) 1 NC_010519.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 2082654 6107758 HSM_1833 Haemophilus somnus 2336 ketol-acid reductoisomerase YP_001785151.1 2081173 R 228400 CDS YP_001785152.1 170718121 6107759 2082909..2084078 1 NC_010519.1 TIGRFAM: trimethylamine-N-oxide reductase c-type cytochrome TorC; PFAM: NapC/NirT cytochrome C domain protein; KEGG: hso:HS_1672 cytochrome C protein; trimethylamine-N-oxide reductase c-type cytochrome TorC 2084078 6107759 HSM_1834 Haemophilus somnus 2336 trimethylamine-N-oxide reductase c-type cytochrome TorC YP_001785152.1 2082909 D 228400 CDS YP_001785153.1 170718122 6107760 2084093..2086561 1 NC_010519.1 TIGRFAM: trimethylamine-N-oxide reductase TorA; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: hso:HS_1673 trimethylamine-N-oxide reductase precursor; trimethylamine-N-oxide reductase TorA 2086561 6107760 HSM_1835 Haemophilus somnus 2336 trimethylamine-N-oxide reductase TorA YP_001785153.1 2084093 D 228400 CDS YP_001785154.1 170718123 6107761 2086558..2087151 1 NC_010519.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 2087151 torD 6107761 torD Haemophilus somnus 2336 chaperone protein TorD YP_001785154.1 2086558 D 228400 CDS YP_001785155.1 170718124 6107762 complement(2087235..2088386) 1 NC_010519.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 2088386 mnmA 6107762 mnmA Haemophilus somnus 2336 tRNA-specific 2-thiouridylase MnmA YP_001785155.1 2087235 R 228400 CDS YP_001785156.1 170718125 6107763 complement(2088421..2088933) 1 NC_010519.1 KEGG: hso:HS_1684 Haemophilus-specific protein, uncharacterized; hypothetical protein 2088933 6107763 HSM_1838 Haemophilus somnus 2336 hypothetical protein YP_001785156.1 2088421 R 228400 CDS YP_001785157.1 170718126 6107764 complement(2088973..2089227) 1 NC_010519.1 PFAM: protein of unknown function DUF539; KEGG: hso:HS_1685 hypothetical protein; hypothetical protein 2089227 6107764 HSM_1839 Haemophilus somnus 2336 hypothetical protein YP_001785157.1 2088973 R 228400 CDS YP_001785158.1 170718128 6107765 complement(2089237..2090286) 1 NC_010519.1 PFAM: ApbE family lipoprotein; KEGG: hso:HS_1686 thiamine biosynthesis lipoprotein; ApbE family lipoprotein 2090286 6107765 HSM_1840 Haemophilus somnus 2336 ApbE family lipoprotein YP_001785158.1 2089237 R 228400 CDS YP_001785159.1 170718129 6107767 complement(2090302..2090814) 1 NC_010519.1 TIGRFAM: peptide methionine sulfoxide reductase; PFAM: methionine sulfoxide reductase A; KEGG: hso:HS_1687 peptide methionine sulfoxide reductase MsrA/MsrB; peptide methionine sulfoxide reductase 2090814 6107767 HSM_1841 Haemophilus somnus 2336 peptide methionine sulfoxide reductase YP_001785159.1 2090302 R 228400 CDS YP_001785160.1 170718130 6107768 complement(2090917..2092140) 1 NC_010519.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F 2092140 6107768 HSM_1842 Haemophilus somnus 2336 Na(+)-translocating NADH-quinone reductase subunit F YP_001785160.1 2090917 R 228400 CDS YP_001785161.1 170718131 6107769 complement(2092155..2092751) 1 NC_010519.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.; Na(+)-translocating NADH-quinone reductase subunit E 2092751 6107769 HSM_1843 Haemophilus somnus 2336 Na(+)-translocating NADH-quinone reductase subunit E YP_001785161.1 2092155 R 228400 CDS YP_001785162.1 170718132 6107770 complement(2092755..2093378) 1 NC_010519.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D 2093378 6107770 HSM_1844 Haemophilus somnus 2336 Na(+)-translocating NADH-quinone reductase subunit D YP_001785162.1 2092755 R 228400 CDS YP_001785163.1 170718133 6107771 complement(2093378..2094154) 1 NC_010519.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C 2094154 6107771 HSM_1845 Haemophilus somnus 2336 Na(+)-translocating NADH-quinone reductase subunit C YP_001785163.1 2093378 R 228400 CDS YP_001785164.1 170718134 6107772 complement(2094147..2095385) 1 NC_010519.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B 2095385 6107772 HSM_1846 Haemophilus somnus 2336 Na(+)-translocating NADH-quinone reductase subunit B YP_001785164.1 2094147 R 228400 CDS YP_001785165.1 170718135 6107773 complement(2095388..2096728) 1 NC_010519.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A 2096728 6107773 HSM_1847 Haemophilus somnus 2336 Na(+)-translocating NADH-quinone reductase subunit A YP_001785165.1 2095388 R 228400 CDS YP_001785166.1 170718136 6107774 complement(2097056..2097367) 1 NC_010519.1 PFAM: BolA family protein; KEGG: hso:HS_1694 BolA protein; BolA family protein 2097367 6107774 HSM_1848 Haemophilus somnus 2336 BolA family protein YP_001785166.1 2097056 R 228400 CDS YP_001785167.1 170718137 6107775 complement(2097556..2097984) 1 NC_010519.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 2097984 atpC 6107775 atpC Haemophilus somnus 2336 F0F1 ATP synthase subunit epsilon YP_001785167.1 2097556 R 228400 CDS YP_001785168.1 170718139 6107776 complement(2098027..2099400) 1 NC_010519.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 2099400 6107776 HSM_1850 Haemophilus somnus 2336 F0F1 ATP synthase subunit beta YP_001785168.1 2098027 R 228400 CDS YP_001785169.1 170718140 6107778 complement(2099414..2100283) 1 NC_010519.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 2100283 6107778 HSM_1851 Haemophilus somnus 2336 F0F1 ATP synthase subunit gamma YP_001785169.1 2099414 R 228400 CDS YP_001785170.1 170718141 6107779 complement(2100307..2101848) 1 NC_010519.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 2101848 6107779 HSM_1852 Haemophilus somnus 2336 F0F1 ATP synthase subunit alpha YP_001785170.1 2100307 R 228400 CDS YP_001785171.1 170718142 6107780 complement(2101861..2102409) 1 NC_010519.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the subunit delta is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 2102409 6107780 HSM_1853 Haemophilus somnus 2336 F0F1 ATP synthase subunit delta YP_001785171.1 2101861 R 228400 CDS YP_001785172.1 170718143 6107781 complement(2102423..2102893) 1 NC_010519.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit beta 2102893 6107781 HSM_1854 Haemophilus somnus 2336 F0F1 ATP synthase subunit beta YP_001785172.1 2102423 R 228400 CDS YP_001785173.1 170718144 6107782 complement(2102958..2103212) 1 NC_010519.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit chi 2103212 6107782 HSM_1855 Haemophilus somnus 2336 F0F1 ATP synthase subunit chi YP_001785173.1 2102958 R 228400 CDS YP_001785174.1 170718145 6107783 complement(2103311..2104108) 1 NC_010519.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit alpha 2104108 6107783 HSM_1856 Haemophilus somnus 2336 F0F1 ATP synthase subunit alpha YP_001785174.1 2103311 R 228400 CDS YP_001785175.1 170718146 6107784 complement(2104620..2105282) 1 NC_010519.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 2105282 gidB 6107784 gidB Haemophilus somnus 2336 16S rRNA methyltransferase GidB YP_001785175.1 2104620 R 228400 CDS YP_001785176.1 170718147 6107785 complement(2105282..2107171) 1 NC_010519.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 2107171 6107785 HSM_1858 Haemophilus somnus 2336 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_001785176.1 2105282 R 228400 CDS YP_001785177.1 170718148 6107786 complement(2107551..2108000) 1 NC_010519.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 2108000 6107786 HSM_1859 Haemophilus somnus 2336 flavodoxin YP_001785177.1 2107551 R 228400 CDS YP_001785178.1 170718150 6107787 complement(2108067..2108285) 1 NC_010519.1 PFAM: protein of unknown function DUF904; KEGG: hso:HS_1707 hypothetical protein; hypothetical protein 2108285 6107787 HSM_1860 Haemophilus somnus 2336 hypothetical protein YP_001785178.1 2108067 R 228400 CDS YP_001785179.1 170718151 6107789 2108540..2110963 1 NC_010519.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 2110963 gyrB 6107789 gyrB Haemophilus somnus 2336 DNA gyrase subunit B YP_001785179.1 2108540 D 228400 CDS YP_001785180.1 170718152 6107790 complement(2111328..2113202) 1 NC_010519.1 TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase; HRDC domain protein; DEAD/DEAH box helicase; SMART: DEAD-like helicases; KEGG: hso:HS_1711 ATP-dependent DNA helicase; ATP-dependent DNA helicase RecQ 2113202 6107790 HSM_1862 Haemophilus somnus 2336 ATP-dependent DNA helicase RecQ YP_001785180.1 2111328 R 228400 CDS YP_001785181.1 170718153 6107791 complement(2113202..2113510) 1 NC_010519.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 2113510 cyaY 6107791 cyaY Haemophilus somnus 2336 frataxin-like protein YP_001785181.1 2113202 R 228400 CDS YP_001785182.1 170718154 6107792 2113635..2113766 1 NC_010519.1 KEGG: hit:NTHI0885 hypothetical protein; hypothetical protein 2113766 6107792 HSM_1864 Haemophilus somnus 2336 hypothetical protein YP_001785182.1 2113635 D 228400 CDS YP_001785183.1 170718155 6107793 2113788..2115041 1 NC_010519.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: hso:HS_1713 diaminopimelate decarboxylase; diaminopimelate decarboxylase 2115041 6107793 HSM_1865 Haemophilus somnus 2336 diaminopimelate decarboxylase YP_001785183.1 2113788 D 228400 CDS YP_001785184.1 170718156 6107794 2115305..2116813 1 NC_010519.1 PFAM: sodium:neurotransmitter symporter; KEGG: hso:HS_1714 sodium-dependent transporter (SNF family); sodium:neurotransmitter symporter 2116813 6107794 HSM_1866 Haemophilus somnus 2336 sodium:neurotransmitter symporter YP_001785184.1 2115305 D 228400 CDS YP_001785185.1 170718157 6107795 complement(2117343..2117993) 1 NC_010519.1 PFAM: TfoX domain protein; KEGG: hso:HS_1715 DNA transformation protein; competence-specific genes regulator 2117993 6107795 HSM_1867 Haemophilus somnus 2336 competence-specific genes regulator YP_001785185.1 2117343 R 228400 CDS YP_001785186.1 170718158 6108900 complement(2124060..2124680) 1 NC_010519.1 PFAM: LysR substrate-binding; KEGG: hso:HS_1716 D-serine dehydratase (deaminase) transcriptional activator; LysR family transcriptional regulator 2124680 6108900 HSM_1868 Haemophilus somnus 2336 LysR family transcriptional regulator YP_001785186.1 2124060 R 228400 CDS YP_001785187.1 170718159 6107797 complement(2124957..2125664) 1 NC_010519.1 PFAM: helix-turn-helix domain protein; peptidase S24 S26A and S26B; KEGG: hdu:HD0089 probable transcription regulator; phage repressor 2125664 6107797 HSM_1869 Haemophilus somnus 2336 phage repressor YP_001785187.1 2124957 R 228400 CDS YP_001785188.1 170718161 6107798 2125849..2126118 1 NC_010519.1 KEGG: hdu:HD0090 DNA-binding protein; Nlp family transcripitonal regulator 2126118 6107798 HSM_1870 Haemophilus somnus 2336 Nlp family transcripitonal regulator YP_001785188.1 2125849 D 228400 CDS YP_001785189.1 170718162 6107800 2126129..2128087 1 NC_010519.1 PFAM: Integrase catalytic region; transposase-like Mu; KEGG: sfx:S2951 phage transposase; transposase 2128087 6107800 HSM_1871 Haemophilus somnus 2336 transposase YP_001785189.1 2126129 D 228400 CDS YP_001785190.1 170718163 6107802 complement(2129292..2130413) 1 NC_010519.1 KEGG: hdu:HD1689 transposase; transposase 2130413 6107802 HSM_1874 Haemophilus somnus 2336 transposase YP_001785190.1 2129292 R 228400 CDS YP_001785191.1 170718164 6107803 complement(2130790..2131287) 1 NC_010519.1 hypothetical protein 2131287 6107803 HSM_1875 Haemophilus somnus 2336 hypothetical protein YP_001785191.1 2130790 R 228400 CDS YP_001785192.1 170718165 6107804 2131621..2132025 1 NC_010519.1 PFAM: helix-turn-helix domain protein; KEGG: hit:NTHI0420 hypothetical protein; helix-turn-helix domain-containing protein 2132025 6107804 HSM_1876 Haemophilus somnus 2336 helix-turn-helix domain-containing protein YP_001785192.1 2131621 D 228400 CDS YP_001785193.1 170718166 6107805 2132108..2133055 1 NC_010519.1 KEGG: hdu:HD1543 hypothetical protein; hypothetical protein 2133055 6107805 HSM_1877 Haemophilus somnus 2336 hypothetical protein YP_001785193.1 2132108 D 228400 CDS YP_001785194.1 170718167 6107806 2133039..2133500 1 NC_010519.1 KEGG: hdu:HD1546 hypothetical protein; hypothetical protein 2133500 6107806 HSM_1878 Haemophilus somnus 2336 hypothetical protein YP_001785194.1 2133039 D 228400 CDS YP_001785195.1 170718168 6107807 complement(2133840..2134235) 1 NC_010519.1 hypothetical protein 2134235 6107807 HSM_1879 Haemophilus somnus 2336 hypothetical protein YP_001785195.1 2133840 R 228400 CDS YP_001785196.1 170718170 6107808 complement(2134346..2135887) 1 NC_010519.1 PFAM: N-6 DNA methylase; KEGG: fth:FTH_0955 type I site-specific deoxyribonuclease; N-6 DNA methylase 2135887 6107808 HSM_1880 Haemophilus somnus 2336 N-6 DNA methylase YP_001785196.1 2134346 R 228400 CDS YP_001785197.1 170718171 6107810 complement(2135847..2136245) 1 NC_010519.1 hypothetical protein 2136245 6107810 HSM_1881 Haemophilus somnus 2336 hypothetical protein YP_001785197.1 2135847 R 228400 CDS YP_001785198.1 170718172 6107811 complement(2136356..2136550) 1 NC_010519.1 KEGG: hdu:HD1613 hypothetical protein; hypothetical protein 2136550 6107811 HSM_1882 Haemophilus somnus 2336 hypothetical protein YP_001785198.1 2136356 R 228400 CDS YP_001785199.1 170718173 6107812 2136849..2137502 1 NC_010519.1 KEGG: hso:HS_1709 transposase; transposase 2137502 6107812 HSM_1883 Haemophilus somnus 2336 transposase YP_001785199.1 2136849 D 228400 CDS YP_001785200.1 170718174 6107814 2138784..2139098 1 NC_010519.1 KEGG: hdu:HD1611 hypothetical protein; hypothetical protein 2139098 6107814 HSM_1886 Haemophilus somnus 2336 hypothetical protein YP_001785200.1 2138784 D 228400 CDS YP_001785201.1 170718175 6107815 2139228..2139476 1 NC_010519.1 KEGG: bxe:Bxe_A1012 transposase; transposase 2139476 6107815 HSM_1887 Haemophilus somnus 2336 transposase YP_001785201.1 2139228 D 228400 CDS YP_001785202.1 170718176 6107816 2139936..2141045 1 NC_010519.1 PFAM: ATPase AAA; SMART: AAA ATPase; KEGG: reu:Reut_C6418 ATPase AAA, central region; ATPase 2141045 6107816 HSM_1888 Haemophilus somnus 2336 ATPase YP_001785202.1 2139936 D 228400 CDS YP_001785203.1 170718177 6107817 2141042..2143234 1 NC_010519.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: reu:Reut_C6419 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 2143234 6107817 HSM_1889 Haemophilus somnus 2336 peptidase S8/S53 subtilisin kexin sedolisin YP_001785203.1 2141042 D 228400 CDS YP_001785204.1 170718178 6107818 complement(2143369..2143800) 1 NC_010519.1 KEGG: hdu:HD1698 hypothetical protein; hypothetical protein 2143800 6107818 HSM_1890 Haemophilus somnus 2336 hypothetical protein YP_001785204.1 2143369 R 228400 CDS YP_001785205.1 170718179 6107820 2143886..2144419 1 NC_010519.1 PFAM: gluconate transporter; KEGG: hso:HS_1717 D-serine permease; gluconate transporter 2144419 6107820 HSM_1891 Haemophilus somnus 2336 gluconate transporter YP_001785205.1 2143886 D 228400 CDS YP_001785206.1 170718180 6107821 2144430..2145746 1 NC_010519.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 2145746 6107821 HSM_1892 Haemophilus somnus 2336 D-serine dehydratase YP_001785206.1 2144430 D 228400 CDS YP_001785207.1 170718181 6108902 2146603..2148000 1 NC_010519.1 PFAM: Nicotinate phosphoribosyltransferase and related; KEGG: hso:HS_0002 nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase 2148000 6108902 HSM_1893 Haemophilus somnus 2336 nicotinate phosphoribosyltransferase YP_001785207.1 2146603 D 228400 CDS YP_001785208.1 170718182 6107823 complement(2148077..2148541) 1 NC_010519.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 2148541 6107823 HSM_1894 Haemophilus somnus 2336 xanthine-guanine phosphoribosyltransferase YP_001785208.1 2148077 R 228400 CDS YP_001785209.1 170718183 6107824 2148666..2150126 1 NC_010519.1 TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: hso:HS_0004 Xaa-His dipeptidase (aminoacyl-histidine dipeptidase); aminoacyl-histidine dipeptidase 2150126 6107824 HSM_1895 Haemophilus somnus 2336 aminoacyl-histidine dipeptidase YP_001785209.1 2148666 D 228400 CDS YP_001785210.1 170718184 6107825 complement(2150274..2152853) 1 NC_010519.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2152853 6107825 HSM_1896 Haemophilus somnus 2336 DNA mismatch repair protein MutS YP_001785210.1 2150274 R 228400 CDS YP_001785211.1 170718185 6107826 complement(2152986..2153801) 1 NC_010519.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 2153801 aroE 6107826 aroE Haemophilus somnus 2336 shikimate 5-dehydrogenase YP_001785211.1 2152986 R 228400 CDS YP_001785212.1 170718186 6107827 complement(2153805..2154356) 1 NC_010519.1 PFAM: SUA5/yciO/yrdC domain; KEGG: hso:HS_0007 translation factor, SUA5 family; SUA5/yciO/yrdC domain-containing protein 2154356 6107827 HSM_1898 Haemophilus somnus 2336 SUA5/yciO/yrdC domain-containing protein YP_001785212.1 2153805 R 228400 CDS YP_001785213.1 170718187 6107828 complement(2154353..2154901) 1 NC_010519.1 PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: hso:HS_0008 DNA topoisomerase I-related protein; DNA topoisomerase type IA Zn finger domain-containing protein 2154901 6107828 HSM_1899 Haemophilus somnus 2336 DNA topoisomerase type IA Zn finger domain-containing protein YP_001785213.1 2154353 R 228400 CDS YP_001785214.1 170718189 6107829 2155035..2155598 1 NC_010519.1 PFAM: protein of unknown function DUF179; KEGG: hso:HS_0009 conserved hypothetical protein; hypothetical protein 2155598 6107829 HSM_1900 Haemophilus somnus 2336 hypothetical protein YP_001785214.1 2155035 D 228400 CDS YP_001785215.1 170718190 6107831 2155598..2156023 1 NC_010519.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 2156023 6107831 HSM_1901 Haemophilus somnus 2336 Holliday junction resolvase-like protein YP_001785215.1 2155598 D 228400 CDS YP_001785216.1 170718191 6107832 complement(2156024..2156782) 1 NC_010519.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: hso:HS_0011 transcriptional regulator of sugar metabolism; DeoR family transcriptional regulator 2156782 6107832 HSM_1902 Haemophilus somnus 2336 DeoR family transcriptional regulator YP_001785216.1 2156024 R 228400 CDS YP_001785217.1 170718192 6107833 2156953..2157861 1 NC_010519.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: hso:HS_0012 3-hydroxyisobutyrate dehydrogenase family protein; 3-hydroxyisobutyrate dehydrogenase 2157861 6107833 HSM_1903 Haemophilus somnus 2336 3-hydroxyisobutyrate dehydrogenase YP_001785217.1 2156953 D 228400 CDS YP_001785218.1 170718193 6107834 2157863..2159104 1 NC_010519.1 PFAM: type III effector Hrp-dependent outers; KEGG: hso:HS_0013 secretion system component; Hrp-dependent type III effector protein 2159104 6107834 HSM_1904 Haemophilus somnus 2336 Hrp-dependent type III effector protein YP_001785218.1 2157863 D 228400 CDS YP_001785219.1 170718194 6107835 2159101..2159733 1 NC_010519.1 PFAM: class II aldolase/adducin family protein; KEGG: hso:HS_0014 L-fuculose-phosphate aldolase, aldolase class II family; aldolase 2159733 6107835 HSM_1905 Haemophilus somnus 2336 aldolase YP_001785219.1 2159101 D 228400 CDS YP_001785220.1 170718195 6107836 2159736..2160518 1 NC_010519.1 PFAM: xylose isomerase; KEGG: hso:HS_0015 hydroxypyruvate isomerase; hydroxypyruvate isomerase 2160518 6107836 HSM_1906 Haemophilus somnus 2336 hydroxypyruvate isomerase YP_001785220.1 2159736 D 228400 CDS YP_001785221.1 170718196 6107837 2160533..2161207 1 NC_010519.1 PFAM: cyclase family protein; KEGG: pmu:PM1362 hypothetical T. maritima; cyclase family protein 2161207 6107837 HSM_1907 Haemophilus somnus 2336 cyclase family protein YP_001785221.1 2160533 D 228400 CDS YP_001785222.1 170718197 6107838 2161209..2163008 1 NC_010519.1 KEGG: pmu:PM1361 kmt1; hypothetical protein 2163008 6107838 HSM_1908 Haemophilus somnus 2336 hypothetical protein YP_001785222.1 2161209 D 228400 CDS YP_001785223.1 170718198 6107839 2163153..2164100 1 NC_010519.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: hso:HS_0016 hypothetical protein; NAD-dependent epimerase/dehydratase 2164100 6107839 HSM_1909 Haemophilus somnus 2336 NAD-dependent epimerase/dehydratase YP_001785223.1 2163153 D 228400 CDS YP_001785224.1 170718200 6107840 2164116..2165588 1 NC_010519.1 TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter; KEGG: hso:HS_0017 GntP family permease (gluconate uptake protein); gluconate transporter 2165588 6107840 HSM_1910 Haemophilus somnus 2336 gluconate transporter YP_001785224.1 2164116 D 228400 CDS YP_001785225.1 170718201 6107842 2166197..2167240 1 NC_010519.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: hso:HS_0018 hypothetical protein; UBA/THIF-type NAD/FAD binding protein 2167240 6107842 HSM_1911 Haemophilus somnus 2336 UBA/THIF-type NAD/FAD binding protein YP_001785225.1 2166197 D 228400 CDS YP_001785226.1 170718202 6107843 2167227..2168402 1 NC_010519.1 PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_0019 permease, major facilitator superfamily; major facilitator transporter 2168402 6107843 HSM_1912 Haemophilus somnus 2336 major facilitator transporter YP_001785226.1 2167227 D 228400 CDS YP_001785227.1 170718203 6107844 complement(2168700..2169449) 1 NC_010519.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: hso:HS_0020 uxu operon regulator; GntR family transcriptional regulator 2169449 6107844 HSM_1913 Haemophilus somnus 2336 GntR family transcriptional regulator YP_001785227.1 2168700 R 228400 CDS YP_001785228.1 170718204 6107845 2169611..2170636 1 NC_010519.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: hso:HS_0021 Zn-binding dehydrogenase; alcohol dehydrogenase 2170636 6107845 HSM_1914 Haemophilus somnus 2336 alcohol dehydrogenase YP_001785228.1 2169611 D 228400 CDS YP_001785229.1 170718205 6107846 2170665..2171648 1 NC_010519.1 TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_0022 dicarboxylate-binding protein; TRAP dicarboxylate transporter subunit DctP 2171648 6107846 HSM_1915 Haemophilus somnus 2336 TRAP dicarboxylate transporter subunit DctP YP_001785229.1 2170665 D 228400 CDS YP_001785230.1 170718206 6107847 2171713..2172192 1 NC_010519.1 PFAM: tripartite ATP-independent periplasmic transporter DctQ component; KEGG: hso:HS_0023 permease (transporter); tripartite ATP-independent periplasmic transporter DctQ 2172192 6107847 HSM_1916 Haemophilus somnus 2336 tripartite ATP-independent periplasmic transporter DctQ YP_001785230.1 2171713 D 228400 CDS YP_001785231.1 170718207 6107848 2172189..2173463 1 NC_010519.1 TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_0024 permease (transporter); TRAP dicarboxylate transporter subunit DctM 2173463 6107848 HSM_1917 Haemophilus somnus 2336 TRAP dicarboxylate transporter subunit DctM YP_001785231.1 2172189 D 228400 CDS YP_001785232.1 170718208 6107849 2173650..2174297 1 NC_010519.1 PFAM: allophanate hydrolase subunit 1; KEGG: hso:HS_0025 allophanate hydrolase, subunit 1; allophanate hydrolase subunit 1 2174297 6107849 HSM_1918 Haemophilus somnus 2336 allophanate hydrolase subunit 1 YP_001785232.1 2173650 D 228400 CDS YP_001785233.1 170718209 6107850 2174294..2175223 1 NC_010519.1 TIGRFAM: urea amidolyase related protein; PFAM: allophanate hydrolase subunit 2; KEGG: hso:HS_0026 allophanate hydrolase, subunit 2; urea amidolyase-like protein 2175223 6107850 HSM_1919 Haemophilus somnus 2336 urea amidolyase-like protein YP_001785233.1 2174294 D 228400 CDS YP_001785234.1 170718211 6107851 2175210..2175953 1 NC_010519.1 PFAM: LamB/YcsF family protein; KEGG: hso:HS_0027 lactam utilization protein; LamB/YcsF family protein 2175953 6107851 HSM_1920 Haemophilus somnus 2336 LamB/YcsF family protein YP_001785234.1 2175210 D 228400 CDS YP_001785235.1 170718212 6107853 2176079..2177266 1 NC_010519.1 KEGG: hso:HS_0028 permease (transporter); permease 2177266 6107853 HSM_1921 Haemophilus somnus 2336 permease YP_001785235.1 2176079 D 228400 CDS YP_001785236.1 170718213 6107854 2177378..2178238 1 NC_010519.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 2178238 6107854 HSM_1922 Haemophilus somnus 2336 DNA-binding transcriptional regulator AraC YP_001785236.1 2177378 D 228400 CDS YP_001785237.1 170718214 6107855 2178426..2179400 1 NC_010519.1 KEGG: hso:HS_0030 sugar ABC transporter sugar-binding protein; sugar ABC transporter sugar-binding protein 2179400 6107855 HSM_1923 Haemophilus somnus 2336 sugar ABC transporter sugar-binding protein YP_001785237.1 2178426 D 228400 CDS YP_001785238.1 170718215 6107856 2179453..2180943 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0031 sugar ABC transporter ATP-binding; ABC transporter 2180943 6107856 HSM_1924 Haemophilus somnus 2336 ABC transporter YP_001785238.1 2179453 D 228400 CDS YP_001785239.1 170718216 6107857 2180927..2181886 1 NC_010519.1 PFAM: inner-membrane translocator; KEGG: hso:HS_0032 sugar ABC transporter permease; monosaccharide-transporting ATPase 2181886 6107857 HSM_1925 Haemophilus somnus 2336 monosaccharide-transporting ATPase YP_001785239.1 2180927 D 228400 CDS YP_001785240.1 170718217 6107858 2181889..2182839 1 NC_010519.1 PFAM: inner-membrane translocator; KEGG: hso:HS_0033 sugar ABC transporter permease; monosaccharide-transporting ATPase 2182839 6107858 HSM_1926 Haemophilus somnus 2336 monosaccharide-transporting ATPase YP_001785240.1 2181889 D 228400 CDS YP_001785241.1 170718218 6107859 2182852..2184444 1 NC_010519.1 PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_0034 sugar kinase; carbohydrate kinase FGGY 2184444 6107859 HSM_1927 Haemophilus somnus 2336 carbohydrate kinase FGGY YP_001785241.1 2182852 D 228400 CDS YP_001785242.1 170718219 6107860 complement(2184566..2185288) 1 NC_010519.1 TIGRFAM: glutaredoxin-family domain protein; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; glutaredoxin; redoxin; KEGG: hso:HS_0035 peroxiredoxin; glutaredoxin family protein 2185288 6107860 HSM_1928 Haemophilus somnus 2336 glutaredoxin family protein YP_001785242.1 2184566 R 228400 CDS YP_001785243.1 170718220 6107861 2185411..2186325 1 NC_010519.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 2186325 6107861 HSM_1929 Haemophilus somnus 2336 DNA-binding transcriptional regulator OxyR YP_001785243.1 2185411 D 228400 CDS YP_001785244.1 170718222 6107862 complement(2186452..2186847) 1 NC_010519.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 2186847 mscL 6107862 mscL Haemophilus somnus 2336 large-conductance mechanosensitive channel YP_001785244.1 2186452 R 228400 CDS YP_001785245.1 170718223 6107864 complement(2186932..2188308) 1 NC_010519.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 2188308 trkA 6107864 trkA Haemophilus somnus 2336 potassium transporter peripheral membrane protein YP_001785245.1 2186932 R 228400 CDS YP_001785246.1 170718224 6107865 complement(2188393..2189781) 1 NC_010519.1 TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: hso:HS_0039 ribosomal RNA small subunit methyltransferase B; sun protein 2189781 6107865 HSM_1932 Haemophilus somnus 2336 sun protein YP_001785246.1 2188393 R 228400 CDS YP_001785247.1 170718225 6107866 complement(2189778..2190731) 1 NC_010519.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 2190731 fmt 6107866 fmt Haemophilus somnus 2336 methionyl-tRNA formyltransferase YP_001785247.1 2189778 R 228400 CDS YP_001785248.1 170718226 6107867 complement(2190806..2191318) 1 NC_010519.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 2191318 def 6107867 def Haemophilus somnus 2336 peptide deformylase YP_001785248.1 2190806 R 228400 CDS YP_001785249.1 170718227 6107868 complement(2191505..2192134) 1 NC_010519.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: hso:HS_0042 nitrate/nitrite response regulator protein; LuxR family transcriptional regulator 2192134 6107868 HSM_1935 Haemophilus somnus 2336 LuxR family transcriptional regulator YP_001785249.1 2191505 R 228400 CDS YP_001785250.1 170718228 6107869 complement(2192149..2194659) 1 NC_010519.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 2194659 cyaA 6107869 cyaA Haemophilus somnus 2336 adenylate cyclase YP_001785250.1 2192149 R 228400 CDS YP_001785251.1 170718229 6107870 2194814..2195779 1 NC_010519.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 2195779 hemC 6107870 hemC Haemophilus somnus 2336 porphobilinogen deaminase YP_001785251.1 2194814 D 228400 CDS YP_001785252.1 170718230 6107871 2195794..2196534 1 NC_010519.1 PFAM: uroporphyrinogen III synthase HEM4; KEGG: hso:HS_0045 uroporphyrinogen-III synthase; uroporphyrinogen III synthase HEM4 2196534 6107871 HSM_1938 Haemophilus somnus 2336 uroporphyrinogen III synthase HEM4 YP_001785252.1 2195794 D 228400 CDS YP_001785253.1 170718231 6107872 2196570..2197934 1 NC_010519.1 PFAM: protein of unknown function DUF513 hemX; KEGG: hso:HS_0046 uroporphyrin-III C-methyltransferase; hypothetical protein 2197934 6107872 HSM_1939 Haemophilus somnus 2336 hypothetical protein YP_001785253.1 2196570 D 228400 CDS YP_001785254.1 170718233 6107873 2197949..2199226 1 NC_010519.1 TIGRFAM: HemY protein; PFAM: HemY domain protein; KEGG: hso:HS_0047 porphyrin biosynthesis protein; HemY protein 2199226 6107873 HSM_1940 Haemophilus somnus 2336 HemY protein YP_001785254.1 2197949 D 228400 CDS YP_001785255.1 170718234 6107875 complement(2199281..2200267) 1 NC_010519.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase; KEGG: hso:HS_0048 tRNA-dihydrouridine synthase A; tRNA-dihydrouridine synthase A 2200267 6107875 HSM_1941 Haemophilus somnus 2336 tRNA-dihydrouridine synthase A YP_001785255.1 2199281 R 228400 CDS YP_001785256.1 170718235 6107876 complement(2200678..2202252) 1 NC_010519.1 PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_0049 sugar kinase, FGGY family; autoinducer-2 (AI-2) kinase 2202252 6107876 HSM_1942 Haemophilus somnus 2336 autoinducer-2 (AI-2) kinase YP_001785256.1 2200678 R 228400 CDS YP_001785257.1 170718236 6107877 complement(2202285..2203244) 1 NC_010519.1 PFAM: sugar-binding domain protein; KEGG: hso:HS_0050 transcriptional regulator, sorbitol operon regulator; DeoR family transcriptional regulator 2203244 6107877 HSM_1943 Haemophilus somnus 2336 DeoR family transcriptional regulator YP_001785257.1 2202285 R 228400 CDS YP_001785258.1 170718237 6107878 2203461..2204969 1 NC_010519.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0051 ABC transporter ATP-binding, sugar transport; ABC transporter 2204969 6107878 HSM_1944 Haemophilus somnus 2336 ABC transporter YP_001785258.1 2203461 D 228400 CDS YP_001785259.1 170718238 6107879 2204978..2205976 1 NC_010519.1 PFAM: inner-membrane translocator; KEGG: hso:HS_0052 ABC transporter permease, sugar transport; monosaccharide-transporting ATPase 2205976 6107879 HSM_1945 Haemophilus somnus 2336 monosaccharide-transporting ATPase YP_001785259.1 2204978 D 228400 CDS YP_001785260.1 170718239 6107880 2205973..2206956 1 NC_010519.1 PFAM: inner-membrane translocator; KEGG: hso:HS_0053 ABC transporter permease, sugar transport; monosaccharide-transporting ATPase 2206956 6107880 HSM_1946 Haemophilus somnus 2336 monosaccharide-transporting ATPase YP_001785260.1 2205973 D 228400 CDS YP_001785261.1 170718240 6107881 2207069..2208088 1 NC_010519.1 KEGG: hso:HS_0054 sugar ABC transporter substrate-binding protein; sugar ABC transporter substrate-binding protein 2208088 6107881 HSM_1947 Haemophilus somnus 2336 sugar ABC transporter substrate-binding protein YP_001785261.1 2207069 D 228400 CDS YP_001785262.1 170718241 6107882 2208107..2208985 1 NC_010519.1 PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: hso:HS_0055 conserved aldolase; aldolase 2208985 6107882 HSM_1948 Haemophilus somnus 2336 aldolase YP_001785262.1 2208107 D 228400 CDS YP_001785263.1 170718242 6107883 2209051..2209353 1 NC_010519.1 PFAM: antibiotic biosynthesis monooxygenase; KEGG: hso:HS_0056 hypothetical protein; autoinducer-2 (AI-2) modifying protein LsrG 2209353 6107883 HSM_1949 Haemophilus somnus 2336 autoinducer-2 (AI-2) modifying protein LsrG YP_001785263.1 2209051 D 228400 CDS YP_001785264.1 170718244 6107884 2209346..2210056 1 NC_010519.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 2210056 6107884 HSM_1950 Haemophilus somnus 2336 ribulose-phosphate 3-epimerase YP_001785264.1 2209346 D 228400 CDS YP_001785265.1 170718245 6107886 2210318..2210629 1 NC_010519.1 PFAM: ribosomal protein S10; KEGG: yps:YPTB3699 30S ribosomal protein S10; 30S ribosomal protein S10 2210629 6107886 HSM_1951 Haemophilus somnus 2336 30S ribosomal protein S10 YP_001785265.1 2210318 D 228400 CDS YP_001785266.1 170718246 6107887 2210646..2211272 1 NC_010519.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 2211272 rplC 6107887 rplC Haemophilus somnus 2336 50S ribosomal protein L3 YP_001785266.1 2210646 D 228400 CDS YP_001785267.1 170718247 6107888 2211288..2211890 1 NC_010519.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 2211890 rplD 6107888 rplD Haemophilus somnus 2336 50S ribosomal protein L4 YP_001785267.1 2211288 D 228400 CDS YP_001785268.1 170718248 6107889 2211887..2212192 1 NC_010519.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 2212192 rplW 6107889 rplW Haemophilus somnus 2336 50S ribosomal protein L23 YP_001785268.1 2211887 D 228400 CDS YP_001785269.1 170718249 6107890 2212213..2213034 1 NC_010519.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 2213034 rplB 6107890 rplB Haemophilus somnus 2336 50S ribosomal protein L2 YP_001785269.1 2212213 D 228400 CDS YP_001785270.1 170718250 6107891 2213061..2213336 1 NC_010519.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 2213336 rpsS 6107891 rpsS Haemophilus somnus 2336 30S ribosomal protein S19 YP_001785270.1 2213061 D 228400 CDS YP_001785271.1 170718251 6107892 2213347..2213679 1 NC_010519.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 2213679 rplV 6107892 rplV Haemophilus somnus 2336 50S ribosomal protein L22 YP_001785271.1 2213347 D 228400 CDS YP_001785272.1 170718252 6107893 2213696..2214403 1 NC_010519.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 2214403 rpsC 6107893 rpsC Haemophilus somnus 2336 30S ribosomal protein S3 YP_001785272.1 2213696 D 228400 CDS YP_001785273.1 170718253 6107894 2214417..2214827 1 NC_010519.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 2214827 rplP 6107894 rplP Haemophilus somnus 2336 50S ribosomal protein L16 YP_001785273.1 2214417 D 228400 CDS YP_001785274.1 170718255 6107895 2214827..2215018 1 NC_010519.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 2215018 6107895 HSM_1960 Haemophilus somnus 2336 50S ribosomal protein L29 YP_001785274.1 2214827 D 228400 CDS YP_001785275.1 170718256 6107897 2215018..2215272 1 NC_010519.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 2215272 rpsQ 6107897 rpsQ Haemophilus somnus 2336 30S ribosomal protein S17 YP_001785275.1 2215018 D 228400 CDS YP_001785276.1 170718257 6107898 2215469..2218075 1 NC_010519.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0069 iron-regulated outer membrane protein; TonB-dependent receptor 2218075 6107898 HSM_1962 Haemophilus somnus 2336 TonB-dependent receptor YP_001785276.1 2215469 D 228400 CDS YP_001785277.1 170718258 6107899 2218272..2218643 1 NC_010519.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 2218643 rplN 6107899 rplN Haemophilus somnus 2336 50S ribosomal protein L14 YP_001785277.1 2218272 D 228400 CDS YP_001785278.1 170718259 6107900 2218656..2218967 1 NC_010519.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 2218967 rplX 6107900 rplX Haemophilus somnus 2336 50S ribosomal protein L24 YP_001785278.1 2218656 D 228400 CDS YP_001785279.1 170718260 6107901 2218985..2219524 1 NC_010519.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 2219524 rplE 6107901 rplE Haemophilus somnus 2336 50S ribosomal protein L5 YP_001785279.1 2218985 D 228400 CDS YP_001785280.1 170718261 6107902 2219536..2219841 1 NC_010519.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 2219841 rpsN 6107902 rpsN Haemophilus somnus 2336 30S ribosomal protein S14 YP_001785280.1 2219536 D 228400 CDS YP_001785281.1 170718262 6107903 2219878..2220270 1 NC_010519.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 2220270 rpsH 6107903 rpsH Haemophilus somnus 2336 30S ribosomal protein S8 YP_001785281.1 2219878 D 228400 CDS YP_001785282.1 170718263 6107904 2220287..2220820 1 NC_010519.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 2220820 rplF 6107904 rplF Haemophilus somnus 2336 50S ribosomal protein L6 YP_001785282.1 2220287 D 228400 CDS YP_001785283.1 170718264 6107905 2220834..2221187 1 NC_010519.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 2221187 rplR 6107905 rplR Haemophilus somnus 2336 50S ribosomal protein L18 YP_001785283.1 2220834 D 228400 CDS YP_001785284.1 170718266 6107906 2221203..2221703 1 NC_010519.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 2221703 rpsE 6107906 rpsE Haemophilus somnus 2336 30S ribosomal protein S5 YP_001785284.1 2221203 D 228400 CDS YP_001785285.1 170718267 6107908 2221707..2221889 1 NC_010519.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 2221889 rpmD 6107908 rpmD Haemophilus somnus 2336 50S ribosomal protein L30 YP_001785285.1 2221707 D 228400 CDS YP_001785286.1 170718268 6107909 2221894..2222328 1 NC_010519.1 late assembly protein; 50S ribosomal protein L15 2222328 rplO 6107909 rplO Haemophilus somnus 2336 50S ribosomal protein L15 YP_001785286.1 2221894 D 228400 CDS YP_001785287.1 170718269 6107910 2222336..2223661 1 NC_010519.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 2223661 secY 6107910 secY Haemophilus somnus 2336 preprotein translocase subunit SecY YP_001785287.1 2222336 D 228400 CDS YP_001785288.1 170718270 6107911 2223689..2223802 1 NC_010519.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 2223802 rpmJ 6107911 rpmJ Haemophilus somnus 2336 50S ribosomal protein L36 YP_001785288.1 2223689 D 228400 CDS YP_001785289.1 170718271 6107912 2223946..2224302 1 NC_010519.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 2224302 rpsM 6107912 rpsM Haemophilus somnus 2336 30S ribosomal protein S13 YP_001785289.1 2223946 D 228400 CDS YP_001785290.1 170718272 6107913 2224318..2224707 1 NC_010519.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 2224707 6107913 HSM_1976 Haemophilus somnus 2336 30S ribosomal protein S11 YP_001785290.1 2224318 D 228400 CDS YP_001785291.1 170718273 6107914 2224737..2225357 1 NC_010519.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 2225357 rpsD 6107914 rpsD Haemophilus somnus 2336 30S ribosomal protein S4 YP_001785291.1 2224737 D 228400 CDS YP_001785292.1 170718274 6107915 2225390..2226379 1 NC_010519.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 2226379 6107915 HSM_1978 Haemophilus somnus 2336 DNA-directed RNA polymerase subunit alpha YP_001785292.1 2225390 D 228400 CDS YP_001785293.1 170718275 6107916 2226421..2226807 1 NC_010519.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 2226807 rplQ 6107916 rplQ Haemophilus somnus 2336 50S ribosomal protein L17 YP_001785293.1 2226421 D 228400 CDS YP_001785294.1 170718277 6107917 complement(2226877..2227563) 1 NC_010519.1 PFAM: metallophosphoesterase; KEGG: hso:HS_0086 hypothetical protein; metallophosphoesterase 2227563 6107917 HSM_1980 Haemophilus somnus 2336 metallophosphoesterase YP_001785294.1 2226877 R 228400 CDS YP_001785295.1 170718278 6107919 complement(2227568..2228845) 1 NC_010519.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 2228845 6107919 HSM_1981 Haemophilus somnus 2336 nicotinamide-nucleotide adenylyltransferase YP_001785295.1 2227568 R 228400 CDS YP_001785296.1 170718279 6107920 complement(2228919..2229158) 1 NC_010519.1 PFAM: protein of unknown function DUF526; KEGG: hso:HS_0088 hypothetical protein; hypothetical protein 2229158 6107920 HSM_1982 Haemophilus somnus 2336 hypothetical protein YP_001785296.1 2228919 R 228400 CDS YP_001785297.1 170718280 6107921 2229506..2230150 1 NC_010519.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 2230150 ribB 6107921 ribB Haemophilus somnus 2336 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001785297.1 2229506 D 228400 CDS YP_001785298.1 170718281 6107922 2230381..2231034 1 NC_010519.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2231034 recO 6107922 recO Haemophilus somnus 2336 DNA repair protein RecO YP_001785298.1 2230381 D 228400 CDS YP_001785299.1 170718282 6107923 2231055..2232374 1 NC_010519.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 2232374 rumA 6107923 rumA Haemophilus somnus 2336 23S rRNA 5-methyluridine methyltransferase YP_001785299.1 2231055 D 228400 CDS YP_001785300.1 170718283 6107924 2232386..2234623 1 NC_010519.1 TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; RelA/SpoT domain protein; KEGG: hso:HS_0095 GTP diphosphokinase (GTP pyrophosphokinase); (p)ppGpp synthetase I SpoT/RelA 2234623 6107924 HSM_1986 Haemophilus somnus 2336 (p)ppGpp synthetase I SpoT/RelA YP_001785300.1 2232386 D 228400 CDS YP_001785301.1 170718284 6107925 2234654..2235010 1 NC_010519.1 PFAM: diacylglycerol kinase; KEGG: hso:HS_0096 diacylglycerol kinase (diglyceride kinase); diacylglycerol kinase 2235010 6107925 HSM_1987 Haemophilus somnus 2336 diacylglycerol kinase YP_001785301.1 2234654 D 228400 CDS YP_001785302.1 170718285 6107926 complement(2235057..2237303) 1 NC_010519.1 TIGRFAM: TonB-dependent lactoferrin and transferrin receptors; TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0582 transferrin binding protein A; TonB-dependent lactoferrin and transferrin receptor 2237303 6107926 HSM_1988 Haemophilus somnus 2336 TonB-dependent lactoferrin and transferrin receptor YP_001785302.1 2235057 R 228400 CDS YP_001785303.1 170718286 6107927 2237622..2238089 1 NC_010519.1 KEGG: hso:HS_0104 hypothetical protein; hypothetical protein 2238089 6107927 HSM_1989 Haemophilus somnus 2336 hypothetical protein YP_001785303.1 2237622 D 228400 CDS YP_001785304.1 170718288 6107928 2238116..2239333 1 NC_010519.1 PFAM: beta-ketoacyl synthase; KEGG: hso:HS_0105 3-oxoacyl-[acyl-carrier-protein] synthase (beta-ketoacyl-ACP synthase); beta-ketoacyl synthase 2239333 6107928 HSM_1990 Haemophilus somnus 2336 beta-ketoacyl synthase YP_001785304.1 2238116 D 228400 CDS YP_001785305.1 170718289 6107930 2239335..2239787 1 NC_010519.1 KEGG: hso:HS_0106 dehydratase; dehydratase 2239787 6107930 HSM_1991 Haemophilus somnus 2336 dehydratase YP_001785305.1 2239335 D 228400 CDS YP_001785306.1 170718290 6107931 2239787..2240515 1 NC_010519.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 2240515 fabG 6107931 fabG Haemophilus somnus 2336 3-ketoacyl-ACP reductase YP_001785306.1 2239787 D 228400 CDS YP_001785307.1 170718291 6107932 2240579..2241826 1 NC_010519.1 PFAM: beta-ketoacyl synthase; KEGG: hso:HS_0108 3-oxoacyl-[acyl-carrier-protein] synthase II; beta-ketoacyl synthase 2241826 6107932 HSM_1993 Haemophilus somnus 2336 beta-ketoacyl synthase YP_001785307.1 2240579 D 228400 CDS YP_001785308.1 170718292 6107933 2241994..2242746 1 NC_010519.1 KEGG: hso:HS_0109 hypothetical protein; hypothetical protein 2242746 6107933 HSM_1994 Haemophilus somnus 2336 hypothetical protein YP_001785308.1 2241994 D 228400 CDS YP_001785309.1 170718293 6107934 2242722..2243483 1 NC_010519.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: hso:HS_0110 1-acyl-sn-glycerol-3-phosphate acyltransferase; phospholipid/glycerol acyltransferase 2243483 6107934 HSM_1995 Haemophilus somnus 2336 phospholipid/glycerol acyltransferase YP_001785309.1 2242722 D 228400 CDS YP_001785310.1 170718294 6107935 2243487..2243744 1 NC_010519.1 KEGG: hso:HS_0111 acyl carrier protein; acyl carrier protein 2243744 6107935 HSM_1996 Haemophilus somnus 2336 acyl carrier protein YP_001785310.1 2243487 D 228400 CDS YP_001785311.1 170718295 6107936 2243760..2244008 1 NC_010519.1 PFAM: phosphopantetheine-binding; KEGG: hso:HS_0112 acyl carrier protein; phosphopantetheine-binding protein 2244008 6107936 HSM_1997 Haemophilus somnus 2336 phosphopantetheine-binding protein YP_001785311.1 2243760 D 228400 CDS YP_001785312.1 170718296 6107937 2244093..2244452 1 NC_010519.1 KEGG: hso:HS_0113 3-hydroxymyristoyl/3-hydroxydecanoyl-[acyl-carrier- protein] dehydratase; (3R)-hydroxymyristoyl-ACP dehydratase 2244452 6107937 HSM_1998 Haemophilus somnus 2336 (3R)-hydroxymyristoyl-ACP dehydratase YP_001785312.1 2244093 D 228400 CDS YP_001785313.1 170718297 6107938 2244445..2244996 1 NC_010519.1 KEGG: hso:HS_0114 hypothetical protein; hypothetical protein 2244996 6107938 HSM_1999 Haemophilus somnus 2336 hypothetical protein YP_001785313.1 2244445 D 228400 CDS YP_001785314.1 170718301 6107939 2244989..2246269 1 NC_010519.1 PFAM: AMP-dependent synthetase and ligase; KEGG: hso:HS_0115 conserved acyl-coenzyme A synthetase-related protein; AMP-dependent synthetase and ligase 2246269 6107939 HSM_2000 Haemophilus somnus 2336 AMP-dependent synthetase and ligase YP_001785314.1 2244989 D 228400 CDS YP_001785315.1 170718302 6107943 2246266..2246994 1 NC_010519.1 PFAM: glycosyl transferase family 2; KEGG: hso:HS_0116 glycosyl transferase, group 2 family protein; glycosyl transferase family protein 2246994 6107943 HSM_2001 Haemophilus somnus 2336 glycosyl transferase family protein YP_001785315.1 2246266 D 228400 CDS YP_001785316.1 170718303 6107944 2246991..2247911 1 NC_010519.1 PFAM: lipid A biosynthesis acyltransferase; KEGG: hso:HS_0117 acyltransferase; lipid A biosynthesis acyltransferase 2247911 6107944 HSM_2002 Haemophilus somnus 2336 lipid A biosynthesis acyltransferase YP_001785316.1 2246991 D 228400 CDS YP_001785317.1 170718304 6107945 2247935..2248360 1 NC_010519.1 KEGG: hso:HS_0118 hypothetical protein; hypothetical protein 2248360 6107945 HSM_2003 Haemophilus somnus 2336 hypothetical protein YP_001785317.1 2247935 D 228400 CDS YP_001785318.1 170718305 6107946 2248440..2248883 1 NC_010519.1 KEGG: hso:HS_0119 conserved thioesterase; thioesterase 2248883 6107946 HSM_2004 Haemophilus somnus 2336 thioesterase YP_001785318.1 2248440 D 228400 CDS YP_001785319.1 170718306 6107947 2248894..2249481 1 NC_010519.1 KEGG: hso:HS_0120 hypothetical protein; hypothetical protein 2249481 6107947 HSM_2005 Haemophilus somnus 2336 hypothetical protein YP_001785319.1 2248894 D 228400 CDS YP_001785320.1 170718307 6107948 2249490..2251781 1 NC_010519.1 KEGG: hso:HS_0121 hypothetical protein; hypothetical protein 2251781 6107948 HSM_2006 Haemophilus somnus 2336 hypothetical protein YP_001785320.1 2249490 D 228400 CDS YP_001785321.1 170718308 6107949 complement(2251922..2253154) 1 NC_010519.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 2253154 6107949 HSM_2007 Haemophilus somnus 2336 D-3-phosphoglycerate dehydrogenase YP_001785321.1 2251922 R 228400 CDS YP_001785322.1 170718309 6107950 complement(2253180..2253839) 1 NC_010519.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 2253839 6107950 HSM_2008 Haemophilus somnus 2336 ribose-5-phosphate isomerase A YP_001785322.1 2253180 R 228400 CDS YP_001785323.1 170718310 6107951 complement(2253935..2255113) 1 NC_010519.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 2255113 6107951 HSM_2009 Haemophilus somnus 2336 coproporphyrinogen III oxidase YP_001785323.1 2253935 R 228400 CDS YP_001785324.1 170718312 6107952 complement(2255113..2255709) 1 NC_010519.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 2255709 6107952 HSM_2010 Haemophilus somnus 2336 deoxyribonucleotide triphosphate pyrophosphatase YP_001785324.1 2255113 R 228400 CDS YP_001785325.1 170718313 6107954 complement(2255899..2256234) 1 NC_010519.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; KEGG: hso:HS_0126 ComE operon protein (competence protein); helix-hairpin-helix repeat-containing competence protein ComEA 2256234 6107954 HSM_2011 Haemophilus somnus 2336 helix-hairpin-helix repeat-containing competence protein ComEA YP_001785325.1 2255899 R 228400 CDS YP_001785326.1 170718314 6107955 complement(2256456..2256845) 1 NC_010519.1 TIGRFAM: endoribonuclease L-PSP; PFAM: endoribonuclease L-PSP; KEGG: hso:HS_0127 translation initiation inhibitor (endoribonuclease L-PSP); endoribonuclease L-PSP 2256845 6107955 HSM_2012 Haemophilus somnus 2336 endoribonuclease L-PSP YP_001785326.1 2256456 R 228400 CDS YP_001785327.1 170718315 6107956 complement(2256906..2257487) 1 NC_010519.1 KEGG: hso:HS_0128 hypothetical protein; hypothetical protein 2257487 6107956 HSM_2013 Haemophilus somnus 2336 hypothetical protein YP_001785327.1 2256906 R 228400 CDS YP_001785328.1 170718316 6107957 complement(2257636..2258643) 1 NC_010519.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; para-aminobenzoate synthase component I 2258643 6107957 HSM_2014 Haemophilus somnus 2336 para-aminobenzoate synthase component I YP_001785328.1 2257636 R 228400 CDS YP_001785329.1 170718317 6107958 2258700..2259269 1 NC_010519.1 catalyzes the formation of anthranilate from chorismate and glutamine; functions in tryptophan biosynthesis; anthranilate synthase component II 2259269 6107958 HSM_2015 Haemophilus somnus 2336 anthranilate synthase component II YP_001785329.1 2258700 D 228400 CDS YP_001785330.1 170718318 6107959 2259422..2259901 1 NC_010519.1 PFAM: ferritin; KEGG: hso:HS_0131 DNA-binding stress protein; ferritin 2259901 6107959 HSM_2016 Haemophilus somnus 2336 ferritin YP_001785330.1 2259422 D 228400 CDS YP_001785331.1 170718319 6107960 complement(2260001..2261359) 1 NC_010519.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 2261359 trmE 6107960 trmE Haemophilus somnus 2336 tRNA modification GTPase TrmE YP_001785331.1 2260001 R 228400 CDS YP_001785332.1 170718320 6107961 complement(2261445..2263070) 1 NC_010519.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 2263070 6107961 HSM_2018 Haemophilus somnus 2336 inner membrane protein translocase component YidC YP_001785332.1 2261445 R 228400 CDS YP_001785333.1 170718321 6107962 complement(2263070..2263330) 1 NC_010519.1 PFAM: protein of unknown function DUF37; KEGG: hso:HS_0134 hypothetical protein; hypothetical protein 2263330 6107962 HSM_2019 Haemophilus somnus 2336 hypothetical protein YP_001785333.1 2263070 R 228400 CDS YP_001785334.1 170718323 6107963 complement(2263294..2263653) 1 NC_010519.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 2263653 rnpA 6107963 rnpA Haemophilus somnus 2336 ribonuclease P YP_001785334.1 2263294 R 228400 CDS YP_001785335.1 170718324 6107965 complement(2263668..2263802) 1 NC_010519.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 2263802 rpmH 6107965 rpmH Haemophilus somnus 2336 50S ribosomal protein L34 YP_001785335.1 2263668 R 228400 CDS