-- dump date   	20140619_105402
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_001783356.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_001783357.1	binds the polymerase to DNA and acts as a sliding clamp
YP_001783358.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
YP_001783359.1	complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons
YP_001783360.1	PFAM: protein of unknown function UPF0270; KEGG: hso:HS_0140 hypothetical protein
YP_001783361.1	FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly
YP_001783362.1	catalyzes the formation of dUMP from dUTP
YP_001783363.1	catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine
YP_001783364.1	Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase
YP_001783365.1	required for 70S ribosome assembly
YP_001783366.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
YP_001783367.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
YP_001783368.1	catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit
YP_001783369.1	KEGG: hso:HS_0148 acetohydroxy acid synthase II, small subunit
YP_001783370.1	PFAM: MOSC domain containing protein; KEGG: hso:HS_0149 hypothetical protein
YP_001783371.1	PFAM: chorismate lyase; KEGG: hso:HS_0150 4-hydroxybenzoate synthetase (chorismate--pyruvate lyase)
YP_001783372.1	KEGG: hso:HS_0151 exoribonuclease II (ribonuclease R); TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; ribonuclease B OB region domain; ribonuclease R winged-helix domain protein; SMART: Cold shock protein
YP_001783373.1	Specifically methylates the ribose of guanosine 2251 in 23S rRNA
YP_001783374.1	PFAM: Sel1 domain protein repeat-containing protein; KEGG: hso:HS_0153 conserved hypothetical protein, with TPR repeat (tetratrico peptide repeat)
YP_001783375.1	catalyzes the O-acetylation of serine
YP_001783376.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_001783377.1	molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA
YP_001783378.1	PFAM: rhodanese; KEGG: hso:HS_0157 conserved hypothetical protein, with rhodanese-like domain
YP_001783379.1	functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB
YP_001783380.1	catalyzes the conversion of 4-hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway
YP_001783381.1	PFAM: rhodanese; KEGG: hso:HS_0160 thiosulfate sulfurtransferase
YP_001783382.1	KEGG: hso:HS_0161 hypothetical protein
YP_001783383.1	PFAM: rhomboid family protein; KEGG: hso:HS_0162 GlpG protein, rhomboid family
YP_001783384.1	PFAM: protein of unknown function DUF177; KEGG: hso:HS_0163 conserved hypothetical protein
YP_001783385.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_001783386.1	KEGG: hso:HS_0164  fatty acid/phospholipid synthesis protein
YP_001783387.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
YP_001783388.1	TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase; KEGG: hso:HS_0166 [acyl-carrier protein] S-malonyltransferase
YP_001783389.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_001783390.1	carries the fatty acid chain in fatty acid biosynthesis
YP_001783391.1	binds directly to 23S ribosomal RNA
YP_001783392.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_001783393.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_001783394.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
YP_001783395.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
YP_001783396.1	enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation
YP_001783397.1	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
YP_001783398.1	catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate
YP_001783399.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001783400.1	KEGG: hso:HS_0178 hypothetical protein
YP_001783401.1	TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; beta-phosphoglucomutase family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hso:HS_0179  phosphatase
YP_001783402.1	PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0181 TonB-dependent outer membrane receptor
YP_001783403.1	PFAM: protein of unknown function UPF0126; KEGG: hso:HS_0182 hypothetical protein
YP_001783404.1	threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway
YP_001783405.1	catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway
YP_001783406.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_001783407.1	KEGG: hso:HS_1548 outer membrane protein P1
YP_001783408.1	PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: hso:HS_1548 outer membrane protein P1
YP_001783409.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme
YP_001783410.1	KEGG: hso:HS_0187 hypothetical protein
YP_001783411.1	catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities
YP_001783412.1	PFAM: dihydrofolate reductase region; KEGG: hso:HS_0189 dihydrofolate reductase
YP_001783413.1	KEGG: hso:HS_0190 hypothetical protein
YP_001783414.1	PFAM: protein of unknown function DUF1212; KEGG: hso:HS_0191 hypothetical protein
YP_001783415.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
YP_001783416.1	Modulates Rho-dependent transcription termination
YP_001783417.1	forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
YP_001783418.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_001783419.1	catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis
YP_001783420.1	PFAM: sodium/glutamate symporter; KEGG: hso:HS_0197 sodium/glutamate symporter (glutamate permease)
YP_001783421.1	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase
YP_001783422.1	PFAM: ATPase AAA; Clp domain protein; ATPase AAA; ATPase AAA-2 domain protein; SMART: ATPase AAA; KEGG: hso:HS_0199 ATP-dependent Clp protease subunit B
YP_001783423.1	PFAM: protein of unknown function DUF606; KEGG: hso:HS_0200 hypothetical protein
YP_001783424.1	catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide
YP_001783425.1	catalyzes the formation of pyruvate from oxaloacetate
YP_001783426.1	TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase subunit beta; KEGG: hso:HS_0203 oxaloacetate decarboxylase subunit beta
YP_001783427.1	TIGRFAM: transaldolase; PFAM: transaldolase; KEGG: hso:HS_0204 transaldolase
YP_001783428.1	determines N-hexane tolerance and is involved in outer membrane permeability
YP_001783429.1	catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate
YP_001783430.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_001783431.1	PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: hso:HS_0208 ferredoxin
YP_001783432.1	PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790  large adhesin
YP_001783433.1	KEGG: mmu:673901 hypothetical protein LOC673901
YP_001783434.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0210 polar amino acid ABC transporter ATP-binding protein
YP_001783435.1	TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0211 amino acid ABC transporter permease
YP_001783436.1	PFAM: extracellular solute-binding protein family 3; KEGG: hso:HS_0212 amino acid ABC transporter substrate-binding
YP_001783437.1	KEGG: hso:HS_0218 Haemophilus-specific protein, uncharacterized
YP_001783438.1	TIGRFAM: anion transporter; PFAM: sodium/sulfate symporter; citrate transporter; KEGG: hso:HS_0219 conserved transporter NadC family
YP_001783439.1	regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity
YP_001783440.1	catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate
YP_001783441.1	PFAM: protein of unknown function UPF0066; KEGG: hso:HS_0222 hypothetical protein
YP_001783442.1	KEGG: dsy:DSY2532 hypothetical protein
YP_001783443.1	KEGG: hso:HS_0222 hypothetical protein
YP_001783444.1	cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source
YP_001783445.1	with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain
YP_001783446.1	functions to transport ribose at high affinity; forms a complex with RbsA2C2B
YP_001783447.1	periplasmic substrate-binding component of the ATP-dependent ribose transporter
YP_001783448.1	catalyzes the formation of D-ribose 5-phosphate from ribose
YP_001783449.1	PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_0226 ribose operon repressor
YP_001783450.1	PFAM: SmpA/OmlA domain protein; KEGG: hso:HS_0227 conserved small protein A
YP_001783451.1	PFAM: 37kDa nucleoid-associated protein; KEGG: hso:HS_0228  nucleoid-associated protein
YP_001783452.1	PFAM: protein of unknown function DUF1414; KEGG: hso:HS_0229 hypothetical protein
YP_001783453.1	PFAM: sulfatase; KEGG: hso:HS_0230 conserved hypothetical protein
YP_001783454.1	Regulatory factor involved in maltose metabolism
YP_001783455.1	forms a tetramer composed of 2 subunit alphas and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm
YP_001783456.1	catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 subunit betas; AB-stereospecific enzyme
YP_001783457.1	PFAM: sulfatase; KEGG: hso:HS_0234 phosphoglycerol transferase
YP_001783458.1	ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex
YP_001783459.1	with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains
YP_001783460.1	PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: pmu:PM1038 d-galactose binding periplasmic protein precursor
YP_001783461.1	catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P
YP_001783462.1	catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism
YP_001783463.1	catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose
YP_001783464.1	PFAM: CBS domain containing protein; transporter-associated region; KEGG: hso:HS_0237 magnesium and cobalt efflux protein
YP_001783465.1	transfers the fatty acyl group on membrane lipoproteins
YP_001783466.1	PFAM: TatD-related deoxyribonuclease; KEGG: hso:HS_0239 deoxyribonuclease, TatD family
YP_001783467.1	PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: hso:HS_0241 peptidylprolyl isomerase (peptidyl-prolyl cis-trans isomerase)
YP_001783468.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_001783469.1	PFAM: protein of unknown function DUF208; KEGG: hso:HS_0243 hypothetical protein
YP_001783470.1	PFAM: polyprenyl synthetase; KEGG: hso:HS_0244 octaprenyl-diphosphate synthase
YP_001783471.1	PFAM: ribosomal protein L21; KEGG: hso:HS_0245 50S ribosomal protein L21
YP_001783472.1	involved in the peptidyltransferase reaction during translation
YP_001783473.1	PFAM: protein of unknown function DUF6 transmembrane; KEGG: hso:HS_0247 hypothetical protein
YP_001783474.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_001783475.1	PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: hso:HS_0249 N-acetyl-anhydromuramyl-L-alanine amidase
YP_001783476.1	KEGG: hso:HS_0250 fimbrial subunit
YP_001783477.1	With ArtMQJI transports arginine across the inner membrane
YP_001783478.1	PFAM: extracellular solute-binding protein family 3; KEGG: hso:HS_0252 arginine ABC transporter substrate-binding protein
YP_001783479.1	with ArtPMJI transports arginine across the inner membrane
YP_001783480.1	with ArtPQJI acts to transport arginine across the inner membrane
YP_001783481.1	KEGG: hso:HS_0255 hypothetical protein
YP_001783482.1	PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: hso:HS_0256 cytochrome d ubiquinol oxidase subunit I
YP_001783483.1	TIGRFAM: cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: hso:HS_0257 cytochrome d ubiquinol oxidase subunit II
YP_001783484.1	TIGRFAM: Pol-Pal system-associated acyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: hso:HS_0258  thioesterase
YP_001783485.1	TIGRFAM: Tol-Pal system TolQ; PFAM: MotA/TolQ/ExbB proton channel; KEGG: hso:HS_0259 biopolymer transporter
YP_001783486.1	membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins
YP_001783487.1	inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins
YP_001783488.1	forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA
YP_001783489.1	TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: hso:HS_0263 peptidoglycan-associated outer membrane lipoprotein (outer membrane protein P6)
YP_001783490.1	KEGG: hso:HS_0264 type II secretory pathway, pseudopilin
YP_001783491.1	KEGG: hso:HS_0265 hypothetical protein
YP_001783492.1	KEGG: hso:HS_0266 hypothetical protein
YP_001783493.1	KEGG: hso:HS_0267 hypothetical protein
YP_001783494.1	TIGRFAM: exodeoxyribonuclease V, subunit gamma; PFAM: exodeoxyribonuclease V RecC subunit; KEGG: hso:HS_0268 exodeoxyribonuclease V, subunit gamma
YP_001783495.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_001783496.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_001783497.1	PFAM: HI0933 family protein; FAD dependent oxidoreductase; KEGG: hso:HS_0271 conserved hypothetical protein
YP_001783498.1	TIGRFAM:  methyltransferase; PFAM: methyltransferase ; methyltransferase type 11; methyltransferase type 12; KEGG: hso:HS_0272  S-adenosylmethionine-dependent methyltransferase
YP_001783499.1	TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na?? symporter; KEGG: hso:HS_0273 sodium/proline symporter
YP_001783500.1	involved in the processing of the 5'end of 16S rRNA
YP_001783501.1	KEGG: hso:HS_0275  glycosyltransferase
YP_001783502.1	PFAM: peptidase U62 modulator of DNA gyrase; KEGG: hso:HS_0276 modulator of DNA gyrase
YP_001783503.1	PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: hso:HS_0277  SAM-dependent methyltransferase
YP_001783504.1	PFAM: inositol monophosphatase; KEGG: hso:HS_0278 inositol-1(or 4)-monophosphatase
YP_001783505.1	TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: hso:HS_0279  tRNA/rRNA methyltransferase
YP_001783506.1	TIGRFAM:  transcriptional regulator, Rrf2 family; iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074; KEGG: hso:HS_0280  transcriptional regulator
YP_001783507.1	catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis
YP_001783508.1	TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: hso:HS_0282 iron-sulfur cofactor synthesis protein
YP_001783509.1	TIGRFAM: iron-sulfur cluster assembly accessory protein; iron-sulfur cluster assembly protein IscA; PFAM: HesB/YadR/YfhF-family protein; KEGG: hso:HS_0283 HesB-family protein
YP_001783510.1	J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins
YP_001783511.1	involved in the maturation of iron-sulfur cluster-containing proteins
YP_001783512.1	TIGRFAM: ferredoxin 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: hso:HS_0286 ferredoxin
YP_001783513.1	Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine
YP_001783514.1	catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate
YP_001783515.1	TIGRFAM: nucleoside transporter; PFAM: Na dependent nucleoside transporter; nucleoside recognition domain protein; Na dependent nucleoside transporter domain protein; KEGG: hso:HS_0289 transporter permease
YP_001783516.1	PFAM: protein of unknown function DUF161; KEGG: hso:HS_0290 hypothetical protein
YP_001783517.1	PFAM: glycosyl transferase family 2; KEGG: hhe:HH0773 hypothetical protein
YP_001783518.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_001783519.1	Essential for efficient processing of 16S rRNA
YP_001783520.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_001783521.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_001783522.1	PFAM:  esterase; KEGG: hso:HS_0297  hydrolase
YP_001783523.1	PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_0298 gluconate utilization operon repressor
YP_001783524.1	PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: hso:HS_0299 tRNA/rRNA methyltransferase
YP_001783525.1	catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome
YP_001783526.1	PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: hso:HS_0301 DNA polymerase III subunit epsilon
YP_001783527.1	PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294 nucleotidyltransferase KEGG: hso:HS_0302  signal-transduction protein
YP_001783528.1	PFAM: PfkB domain protein; KEGG: hso:HS_0303 myo-inositol catabolism protein
YP_001783529.1	PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: hso:HS_0304  transcriptional regulator
YP_001783530.1	PFAM: protein of unknown function DUF548; KEGG: hso:HS_0305  SAM-dependent methyltransferase
YP_001783531.1	catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs
YP_001783532.1	PFAM: protein of unknown function DUF413; KEGG: hso:HS_0307 hypothetical protein
YP_001783533.1	PFAM: DSBA oxidoreductase; KEGG: hso:HS_0308 protein disulfide-isomerase (thiol:disulfide interchange protein)
YP_001783534.1	PFAM: protein of unknown function DUF1040; KEGG: hso:HS_0309 hypothetical protein
YP_001783535.1	in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis
YP_001783536.1	TIGRFAM: oligopeptide transporters, OPT superfamily; oligopeptide transporter OPT family; PFAM: oligopeptide transporter OPT superfamily protein; KEGG: hso:HS_0311 integral membrane protein
YP_001783537.1	PFAM: Sel1 domain protein repeat-containing protein; KEGG: hso:HS_0313 conserved hypothetical protein, with TPR repeat (tetratrico peptide repeat)
YP_001783538.1	KEGG: hso:HS_0314 Haemophilus-specific protein, uncharacterized
YP_001783539.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
YP_001783540.1	lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system protein H
YP_001783541.1	PFAM: protein of unknown function DUF493; KEGG: hso:HS_0317 hypothetical protein
YP_001783542.1	TIGRFAM: lipoprotein A; PFAM: Rare lipoprotein A; KEGG: hso:HS_0319  lipoprotein A
YP_001783543.1	TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: hso:HS_0320 rod shape-determining protein
YP_001783544.1	PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: hso:HS_0321 cell elongation-specific transpeptidase
YP_001783545.1	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
YP_001783546.1	TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: hso:HS_0323 hypothetical protein
YP_001783547.1	PFAM: ABC transporter; KEGG: hso:HS_0325 chelated iron ABC transporter permease
YP_001783548.1	PFAM: transporter permease; ABC-3 protein; KEGG: hso:HS_0326 chelated iron ABC transporter permease
YP_001783549.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0327 iron ABC transporter ATP-binding protein
YP_001783550.1	PFAM: periplasmic solute binding protein; KEGG: hso:HS_0328 chelated iron ABC transporter periplasmic-binding protein
YP_001783551.1	PFAM: DsrC family protein; KEGG: hso:HS_0329 sulfite reductase-like protein
YP_001783552.1	PFAM: protein of unknown function UPF0005; KEGG: hso:HS_0330 conserved integral membrane protein
YP_001783553.1	TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: hso:HS_0331 competence-related protein
YP_001783554.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_001783555.1	forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
YP_001783556.1	catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling
YP_001783557.1	catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway
YP_001783558.1	PFAM: NAD(P)H dehydrogenase (quinone); KEGG: hso:HS_0336 NAD(P)H dehydrogenase (quinone)
YP_001783559.1	KEGG: hso:HS_0337 hypothetical protein
YP_001783560.1	uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function
YP_001783561.1	PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: hso:HS_0339 conserved outer membrane protein
YP_001783562.1	PFAM: protein of unknown function DUF490; KEGG: hso:HS_0340 hypothetical protein
YP_001783563.1	PFAM: Ppx/GppA phosphatase; KEGG: hso:HS_0341 exopolyphosphatase
YP_001783564.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
YP_001783565.1	binds and unfolds substrates as part of the ClpXP protease
YP_001783566.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_001783567.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_001783568.1	PFAM: type II secretion system protein E; general secretory system II protein E domain protein; KEGG: hso:HS_1430 pilin/fimbriae biogenesis protein
YP_001783569.1	PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: hso:HS_1429  transporter
YP_001783570.1	PFAM: cytochrome C assembly protein; KEGG: hso:HS_1428  permease
YP_001783571.1	TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54 helical bundle; SMART: ATPase AAA; KEGG: hso:HS_1427 signal recognition particle protein
YP_001783572.1	role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport
YP_001783573.1	KEGG: hit:NTHI0419 prophage CP4-57-like integrase
YP_001783574.1	TIGRFAM: transposase, IS605 OrfB family; PFAM:  transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: hso:HS_0583 transposase
YP_001783575.1	PFAM: transposase IS200-family protein; KEGG: hso:HS_0666 transposase
YP_001783577.1	PFAM: phage head completion; KEGG: spt:SPA2617  phage gene
YP_001783578.1	PFAM: phage small terminase subunit; KEGG: yps:YPTB3143 hypothetical protein
YP_001783579.1	TIGRFAM: phage major capsid protein, P2 family; PFAM: phage major capsid protein P2; KEGG: pat:Patl_0697 phage major capsid protein, P2 family
YP_001783581.1	PFAM: phage capsid scaffolding; KEGG: hch:HCH_00395 flagellar biosynthesis/type III secretory pathway protein
YP_001783582.1	PFAM: protein of unknown function DUF264; terminase ATPase; KEGG: yps:YPTB3140  [Haemophilus phage HP1] orf16-like phage protein
YP_001783583.1	TIGRFAM: phage portal protein, PBSX family; PFAM: phage portal protein; KEGG: sgl:SG0244  phage capsid portal protein
YP_001783584.1	PFAM: phage transcriptional activator Ogr/delta; KEGG: yps:YPTB3138  (AB008550) orf34 [bacteriophage phi CTX]
YP_001783586.1	PFAM: N-6 DNA methylase; KEGG: ldb:Ldb1052 type I restriction-modification system, modification subunit
YP_001783588.1	KEGG: pmu:PM1782 unknown
YP_001783590.1	KEGG: hso:HS_0528 hypothetical protein
YP_001783591.1	KEGG: hso:HS_0527 hypothetical protein
YP_001783592.1	PFAM: DNA methylase N-4/N-6 domain protein; KEGG: hit:NTHI1495 modification methylase DpnIIB-like
YP_001783593.1	KEGG: pmu:PM1778 unknown
YP_001783596.1	KEGG: vei:Veis_1323 hypothetical protein
YP_001783598.1	KEGG: nma:NMA1837 hypothetical protein
YP_001783599.1	KEGG: nma:NMA1838 hypothetical DNA-binding protein
YP_001783600.1	TIGRFAM: Addiction module killer protein HI1419; PFAM: protein of unknown function DUF891; KEGG: bxe:Bxe_B0862 hypothetical protein
YP_001783601.1	TIGRFAM: Addiction module antidote protein HI1420; KEGG: pfo:Pfl_2007 predicted transcriptional regulator
YP_001783602.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_001783603.1	PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: hso:HS_1363 hypothetical protein
YP_001783604.1	catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis
YP_001783605.1	PFAM: protein of unknown function DUF535; KEGG: hso:HS_1361 hypothetical protein
YP_001783606.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
YP_001783607.1	catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis
YP_001783608.1	catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM
YP_001783609.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_001783610.1	forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis
YP_001783611.1	PFAM: nitrogen regulatory protein P-II; KEGG: hso:HS_1355 nitrogen regulatory protein p-II
YP_001783612.1	PFAM: protein of unknown function UPF0118; KEGG: hso:HS_1354  permease
YP_001783613.1	involved in methylation of ribosomal protein L3
YP_001783614.1	PFAM: Smr protein/MutS2; KEGG: hso:HS_1352 hypothetical protein
YP_001783615.1	TIGRFAM: hypothetical membrane protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: hso:HS_1351  membrane protein
YP_001783616.1	catalyzes the formation of methylglyoxal from glycerone phosphate
YP_001783617.1	KEGG: hso:HS_1349 hypothetical protein
YP_001783618.1	PFAM: Hemolysin activator HlyB domain protein; polypeptide-transport-associated domain protein ShlB-type; KEGG: msu:MS1169 FhaC protein
YP_001783619.1	TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: nme:NMB1768 hemagglutinin/hemolysin-related protein
YP_001783620.1	KEGG: nme:NMB1764 hypothetical protein
YP_001783621.1	KEGG: nme:NMB1768 hemagglutinin/hemolysin-related protein
YP_001783622.1	KEGG: nme:NMB1502 hypothetical protein
YP_001783623.1	KEGG: msu:MS1162 hypothetical protein
YP_001783625.1	KEGG: mfa:Mfla_0483 adhesin HecA 20-residue repeat X2
YP_001783628.1	catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity
YP_001783629.1	TIGRFAM: thioredoxin; PFAM: thioredoxin domain; KEGG: hso:HS_1344 thioredoxin
YP_001783630.1	controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP
YP_001783631.1	TIGRFAM: uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease; KEGG: hso:HS_1342 uracil permease
YP_001783632.1	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate
YP_001783633.1	PFAM: glutamine amidotransferase class-II; KEGG: hso:HS_1340 conserved hypothetical protein
YP_001783634.1	converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer
YP_001783635.1	KEGG: hso:HS_1338 hypothetical protein
YP_001783636.1	PFAM: glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: hso:HS_1330 beta-glucuronidase
YP_001783637.1	PFAM: PfkB domain protein; KEGG: hso:HS_1329 2-keto-3-deoxygluconate kinase
YP_001783638.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_001783639.1	PFAM: peptidase U62 modulator of DNA gyrase; KEGG: hso:HS_1327 antibiotic maturation factor
YP_001783640.1	PFAM: protein of unknown function DUF615; KEGG: hso:HS_1326 hypothetical protein
YP_001783641.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_001783642.1	catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA
YP_001783643.1	PFAM: peptidase U32; KEGG: hso:HS_1323 collagenase PrtC
YP_001783644.1	KEGG: hso:HS_1322 Haemophilus-specific protein, uncharacterized
YP_001783645.1	KEGG: hso:HS_1321 Haemophilus-specific protein, uncharacterized
YP_001783647.1	KEGG: hso:HS_1320 Haemophilus-specific protein, uncharacterized
YP_001783648.1	KEGG: hso:HS_1319 C4-dicarboxylate transporter, C4-dicarboxylate-binding protein
YP_001783649.1	PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_1319 C4-dicarboxylate transporter, C4-dicarboxylate-binding protein
YP_001783650.1	PFAM: tripartite ATP-independent periplasmic transporter DctQ component; KEGG: hso:HS_1318 C4-dicarboxylate transporter, small subunit
YP_001783651.1	TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: citrate transporter; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_1317 C4-dicarboxylate transporter, large subunit (permease)
YP_001783652.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
YP_001783653.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
YP_001783654.1	member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex
YP_001783655.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
YP_001783656.1	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_001783657.1	TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: hso:HS_1311 protein-export membrane protein
YP_001783658.1	decatenates replicating daughter chromosomes
YP_001783659.1	PFAM: conserved hypothetical protein 103; KEGG: hso:HS_1309 hypothetical protein
YP_001783660.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_001783661.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
YP_001783662.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_001783663.1	binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities
YP_001783664.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_001783665.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1302 ABC transporter ATP-binding protein
YP_001783666.1	PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: hso:HS_1301 FKBP-type peptidyl-prolyl cis-trans isomerase
YP_001783667.1	catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine
YP_001783668.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
YP_001783669.1	TIGRFAM: dihydroneopterin aldolase; KEGG: hso:HS_1298 dihydroneopterin aldolase
YP_001783670.1	PFAM: protein of unknown function DUF205; KEGG: hso:HS_1297 conserved hypothetical protein
YP_001783671.1	PFAM: methyltransferase small; KEGG: hso:HS_1296  SAM-dependent methyltransferase
YP_001783672.1	facilitates an early step in the assembly of the 50S subunit of the ribosome
YP_001783673.1	PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: hso:HS_1294 conserved hypothetical protein
YP_001783674.1	PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: hso:HS_1293 hypothetical protein
YP_001783675.1	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs
YP_001783676.1	functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system
YP_001783677.1	PFAM: dihydrouridine synthase; KEGG: hso:HS_1290 tRNA-dihydrouridine synthase C
YP_001783678.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_001783679.1	TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: radical SAM protein; KEGG: hso:HS_1288 hypothetical protein
YP_001783680.1	PFAM: Opacity-associated protein A; KEGG: hso:HS_1287 opacity associated protein A
YP_001783681.1	Required for efficient pilin antigenic variation
YP_001783682.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
YP_001783683.1	transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters
YP_001783684.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
YP_001783685.1	KEGG: hso:HS_0337 hypothetical protein
YP_001783686.1	KEGG: hso:HS_0337 hypothetical protein
YP_001783687.1	PFAM: YadA domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790  large adhesin
YP_001783688.1	KEGG: hso:HS_1184 hypothetical protein
YP_001783689.1	PFAM: hypothetical protein; KEGG: hso:HS_1183  permease
YP_001783690.1	PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: hso:HS_1548 outer membrane protein P1
YP_001783691.1	TIGRFAM: molybdenum ABC transporter periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_1182 molybdenum ABC transporter periplasmic binding protein
YP_001783692.1	part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE
YP_001783693.1	catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme
YP_001783694.1	KEGG: hso:HS_1217 hypothetical protein
YP_001783695.1	PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0209  large adhesin
YP_001783696.1	bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
YP_001783697.1	PFAM: alanine racemase domain protein; KEGG: hso:HS_1215 hypothetical protein
YP_001783698.1	multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways
YP_001783699.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
YP_001783700.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_001783701.1	PFAM: ferric-uptake regulator; KEGG: hso:HS_1211 ferric uptake regulation protein
YP_001783702.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_001783703.1	PFAM: alpha/beta hydrolase; PGAP1 family protein; KEGG: hso:HS_1209 esterase/lipase
YP_001783704.1	negative modulator of the initiation of chromosome replication
YP_001783705.1	TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: hso:HS_1207 O-succinylbenzoic acid--CoA ligase
YP_001783706.1	small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS
YP_001783707.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_001783708.1	D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm
YP_001783709.1	PFAM: protein of unknown function DUF81; KEGG: hso:HS_1203 conserved hypothetical protein
YP_001783710.1	transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA
YP_001783711.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_001783712.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
YP_001783713.1	23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance
YP_001783714.1	TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: hypothetical protein; Tetratricopeptide TPR_2 repeat protein; SMART: hypothetical protein; KEGG: hso:HS_1197 fimbrial biogenesis and twitching motility protein
YP_001783715.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_001783716.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_001783717.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_001783718.1	PFAM: polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; KEGG: hso:HS_1193 tRNA nucleotidyltransferase
YP_001783719.1	SMART: SH3 domain protein; KEGG: hso:HS_1192 hypothetical protein
YP_001783720.1	PFAM: phosphate transporter; KEGG: hso:HS_1191 phosphate permease
YP_001783721.1	PFAM: protein of unknown function DUF47; KEGG: hso:HS_1190  phosphate transport regulator
YP_001783722.1	PFAM: adenylate cyclase; KEGG: hso:HS_1189 hypothetical protein
YP_001783723.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_001783724.1	mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid ABC transporterer
YP_001783725.1	PFAM: cell divisionFtsK/SpoIIIE; KEGG: hso:HS_1186 DNA translocase protein
YP_001783726.1	PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1616  large adhesin
YP_001783727.1	PFAM: peptidylprolyl isomerase FKBP-type; KEGG: hso:HS_1631 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase)
YP_001783728.1	PFAM: protein of unknown function DUF1260; KEGG: hso:HS_1630 hypothetical protein
YP_001783729.1	TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: hso:HS_1629  tRNA/rRNA methyltransferase
YP_001783730.1	PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP
YP_001783731.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_001783732.1	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
YP_001783733.1	PFAM: sulfatase; KEGG: pmu:PM0223 DcaA protein
YP_001783734.1	involved in de novo purine biosynthesis
YP_001783735.1	PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: hso:HS_1624 SprT protein
YP_001783736.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_001783737.1	hydrolyzes diadenosine polyphosphate
YP_001783738.1	PFAM: protein of unknown function DUF81; KEGG: hso:HS_1621  permease
YP_001783739.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_001783740.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
YP_001783741.1	PFAM: CMP/dCMP deaminase zinc-binding; KEGG: hso:HS_1618 hypothetical protein
YP_001783742.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-subunit beta is inserted between the strands, where it probes for the presence of a lesion
YP_001783743.1	PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1616  large adhesin
YP_001783744.1	PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; tryptophan halogenase; KEGG: hso:HS_1615  dehydrogenase
YP_001783745.1	PFAM: protein of unknown function DUF195; KEGG: hso:HS_1614  DNA recombination protein RmuC
YP_001783746.1	catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose
YP_001783747.1	TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9; KEGG: hso:HS_1612 ADP-heptose--LPS heptosyltransferase II
YP_001783748.1	TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: hso:HS_1611 lipopolysaccharide heptosyltransferase-1
YP_001783749.1	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
YP_001783750.1	KEGG: hso:HS_0337 hypothetical protein
YP_001783751.1	TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; KEGG: hso:HS_1609 molybdopterin-guanine dinucleotide biosynthesis protein B
YP_001783752.1	PFAM: Positive regulator of sigma(E) RseC/MucC; KEGG: hso:HS_1608  positive sigma-E factor regulatory protein
YP_001783753.1	periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP
YP_001783754.1	PFAM: anti sigma-E protein RseA family protein; anti sigma-E protein RseA domain protein; KEGG: hso:HS_1606 sigma-E factor negative regulatory protein
YP_001783755.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response
YP_001783756.1	PFAM: protein of unknown function DUF339; KEGG: hso:HS_1604 hypothetical protein
YP_001783757.1	catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate
YP_001783758.1	catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism
YP_001783759.1	TIGRFAM: sugar (glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_1601 glucuronide permease
YP_001783760.1	PFAM: glycoside hydrolase; KEGG: hso:HS_1600  beta-hexosamidase A, glycoside hydrolase family 3
YP_001783761.1	KEGG: hso:HS_1599 hypothetical protein
YP_001783762.1	Converts D-mannonate to D-mannuronate
YP_001783763.1	PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: hso:HS_1597 uxu operon regulator
YP_001783764.1	catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate
YP_001783765.1	KEGG: hso:HS_1595 hypothetical protein
YP_001783766.1	HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis
YP_001783767.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
YP_001783768.1	KEGG: hso:HS_1592  acetyltransferase, GNAT family
YP_001783769.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
YP_001783770.1	catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A
YP_001783771.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_001783772.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1588 ABC transporter permease/ATP-binding protein
YP_001783773.1	PFAM: myo-inositol catabolism IolB domain protein; KEGG: hso:HS_1587 conserved hypothetical protein
YP_001783774.1	PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_1586 permease,  MFS superfamily
YP_001783775.1	KEGG: hso:HS_1585 hypothetical protein
YP_001783776.1	TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: hso:HS_1584 NAD-dependent aldehyde dehydrogenase
YP_001783777.1	PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: hso:HS_1583  dehydrogenase
YP_001783778.1	PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_1582 ABC transporter periplasmic sugar-binding protein
YP_001783779.1	PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_1581 ABC transporter periplasmic sugar-binding protein
YP_001783780.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1580 sugar ABC transporter ATP-binding protein
YP_001783781.1	PFAM: inner-membrane translocator; KEGG: hso:HS_1579 ABC transporter  ribose permease
YP_001783782.1	PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: hso:HS_1578 myo-inositol catabolism protein
YP_001783783.1	PFAM: xylose isomerase; KEGG: hso:HS_1577 myo-inositol catabolism protein
YP_001783784.1	PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: hso:HS_1576 dehydrogenase
YP_001783785.2	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_001783786.1	catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system
YP_001783787.1	PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: hso:HS_1573 ornithine decarboxylase
YP_001783788.1	KEGG: pmu:PM0805 unknown
YP_001783789.1	PFAM: SirA family protein; KEGG: hso:HS_1572 hypothetical protein
YP_001783790.1	PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: hso:HS_1571 hypothetical protein
YP_001783791.1	TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: hso:HS_1570 potassium uptake system protein
YP_001783792.1	catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX
YP_001783793.1	KEGG: bce:BC4488 hypothetical protein
YP_001783794.1	KEGG: cps:CPS_2955 hypothetical protein
YP_001783796.1	catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway
YP_001783797.1	KEGG: hso:HS_1518 hypothetical protein
YP_001783798.1	PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIsubunit alpha; KEGG: vfi:VF0607 PTS system, diacetylchitobiose-specific IIA component
YP_001783799.1	PFAM: phosphotransferase system lactose/cellobiose-specific IIsubunit beta; KEGG: vfi:VF0604 PTS system, cellobiose-specific IIB component
YP_001783800.1	PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: rma:Rmag_0211 leucyl aminopeptidase
YP_001783801.1	PFAM: peptidase T2 asparaginase 2; KEGG: lga:LGAS_1433 asparaginase
YP_001783802.1	TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PTS system, cellobiose-specific IIC subunit; PFAM: phosphotransferase system EIIC; KEGG: bsu:BG10562  PTS cellobiose-specific enzyme IIC component
YP_001783803.1	PFAM: CutC family protein; KEGG: hso:HS_1517 copper homeostasis protein
YP_001783804.1	transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA
YP_001783805.1	PFAM: pseudouridine synthase; KEGG: hso:HS_1515 ribosomal large subunit pseudouridine synthase A
YP_001783806.1	PFAM: peptidase M48 Ste24p; KEGG: hso:HS_1514 hypothetical protein
YP_001783807.1	catalyzes the hydrolysis of pyrophosphate to phosphate
YP_001783808.1	TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; KEGG: hso:HS_1562 tryptophan-specific transporter
YP_001783809.1	regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity
YP_001783810.1	PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: hso:HS_1560 peptidyl-prolyl cis-trans isomerase, PPIC-type
YP_001783811.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_001783812.1	hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP
YP_001783813.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_001783814.1	PFAM: Rare lipoprotein B; KEGG: hso:HS_1556 conserved hypothetical protein
YP_001783815.1	required for the assembly and function of the DNAX complex which is required for the assembly of the subunit beta onto primed DNA
YP_001783816.1	TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: ATPase AAA; KEGG: hso:HS_1554 cell-division ATP-binding protein
YP_001783817.1	ABC transporter membrane protein
YP_001783818.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
YP_001783819.1	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
YP_001783820.1	MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair
YP_001783821.1	TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: hso:HS_1549 methylated-DNA-protein-cysteine methyltransferase
YP_001783822.1	PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: hso:HS_1548 outer membrane protein P1
YP_001783823.1	KEGG: hso:HS_1548 outer membrane protein P1
YP_001783824.1	PFAM: conserved hypothetical protein 743; KEGG: hso:HS_1547 hypothetical protein
YP_001783825.1	PFAM: pirin; Cupin 2 conserved barrel domain protein; KEGG: hso:HS_1546 conserved hypothetical protein
YP_001783826.1	binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters
YP_001783827.1	KEGG: hso:HS_1544 hypothetical protein
YP_001783828.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_001783829.1	PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: hso:HS_1510 nitrate/nitrite sensor protein
YP_001783830.1	PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases; KEGG: dvl:Dvul_0853 type III restriction enzyme, res subunit
YP_001783831.1	KEGG: hit:NTHI0317 conserved hypothetical DNA binding protein
YP_001783832.1	PFAM: restriction modification system DNA specificity domain; KEGG: mbu:Mbur_0508 restriction modification system DNA specificity subunit
YP_001783835.1	KEGG: gka:GK0575 hypothetical protein
YP_001783836.1	PFAM: NapD family protein; KEGG: hso:HS_1509 periplasmic nitrate reductase, component NapD
YP_001783837.1	periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC
YP_001783838.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway
YP_001783839.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA
YP_001783840.1	PFAM: nitrate reductase cytochrome C subunit (NapB); KEGG: hso:HS_1505 periplasmic nitrate reductase
YP_001783841.1	PFAM: NapC/NirT cytochrome C domain protein; KEGG: hso:HS_1504 cytochrome C protein
YP_001783842.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
YP_001783843.1	PFAM: peptidoglycan-binding LysM; peptidase M23B; KEGG: hso:HS_1502 lipoprotein B
YP_001783844.1	PFAM: SNARE associated Golgi protein; KEGG: hso:HS_1501  lipoprotein B
YP_001783845.1	catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate
YP_001783846.1	catalyzes the modification of U13 in tRNA(Glu)
YP_001783847.1	catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate
YP_001783848.1	TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: hso:HS_1497 glutathione-regulated potassium-efflux system protein
YP_001783849.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
YP_001783850.1	forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein
YP_001783851.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_001783852.1	PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: hso:HS_1493 transcription accessory protein, RNA-binding protein containing S1 domain
YP_001783853.1	PFAM: branched-chain amino acid ABC transporterer II carrier protein; KEGG: hso:HS_1492 branched-chain amino acid carrier protein
YP_001783854.1	cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source
YP_001783855.1	KEGG: hso:HS_1490 competence protein
YP_001783856.1	TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: hso:HS_1489  Cof protein
YP_001783857.1	PFAM: aminodeoxychorismate lyase; KEGG: hso:HS_1488 hypothetical protein
YP_001783858.1	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
YP_001783859.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the subunit beta on the DNA
YP_001783860.1	TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: hso:HS_1485 conserved hypothetical protein
YP_001783861.1	PFAM: protein of unknown function DUF1523; KEGG: hso:HS_1484 hypothetical protein
YP_001783862.1	PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: hso:HS_1483 hypothetical protein
YP_001783863.1	KEGG: hso:HS_1482 hypothetical protein
YP_001783864.1	KEGG: hso:HS_1481 hypothetical protein
YP_001783865.1	PFAM: GPR1/FUN34/yaaH family protein; KEGG: hso:HS_1480 conserved hypothetical protein
YP_001783866.1	Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance
YP_001783867.1	KEGG: hso:HS_1478 hypothetical protein
YP_001783868.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_001783869.1	TIGRFAM: peptide chain release factor 2; PFAM: class I peptide chain release factor; PCRF domain protein; KEGG: msu:MS1542 protein chain release factor B
YP_001783870.1	KEGG: hso:HS_1475 thiol:disulfide interchange protein
YP_001783871.1	TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: hso:HS_1474 single-strand DNA-specific exonuclease
YP_001783872.1	KEGG: hit:NTHI1387 hypothetical protein
YP_001783873.1	enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine
YP_001783874.1	KEGG: hin:HI1720 hypothetical protein
YP_001783875.1	KEGG: hin:HI1721 transposase
YP_001783876.1	KEGG: hin:HI1721 transposase
YP_001783877.1	PFAM: ribosomal protein L31; KEGG: hso:HS_1472 50S ribosomal protein L31
YP_001783878.1	TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein; KEGG: hso:HS_1470 conserved hypothetical protein
YP_001783879.1	Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates
YP_001783880.1	activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions
YP_001783881.1	PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; SMART: HNH nuclease; KEGG: pau:PA14_07480  reverse transcriptase
YP_001783882.1	TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: hso:HS_1466 glyceraldehyde 3-phosphate dehydrogenase
YP_001783883.1	KEGG: hso:HS_1465 hypothetical protein
YP_001783884.1	PFAM: Choline/ethanolamine kinase; KEGG: hso:HS_1461 LicA protein
YP_001783885.1	PFAM: protein of unknown function DUF6 transmembrane; KEGG: hso:HS_1460  lic-1 operon protein (LicB)
YP_001783886.1	KEGG: hso:HS_1459 LicC protein
YP_001783887.1	PFAM: LicD family protein; KEGG: hso:HS_1458 lipopolysaccharide choline phosphotransferase
YP_001783888.1	Essential for recycling GMP and indirectly, cGMP
YP_001783889.1	promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and subunit alphas
YP_001783890.1	KEGG: hso:HS_1455 guanosine-3'5'-bis(diphosphate) 3'-pyrophosphohydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region
YP_001783891.1	catalyzes branch migration in Holliday junction intermediates
YP_001783892.1	converts L-glutamate to D-glutamate, a component of peptidoglycan
YP_001783893.1	PFAM: protein of unknown function DUF6 transmembrane; KEGG: hso:HS_1567 permease,  drug/metabolite transporter superfamily
YP_001783894.1	functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters
YP_001783895.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; subunit beta is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_001783896.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_001783897.1	involved in rpiB and als operon repression
YP_001783898.1	PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ecj:JW4049 D-allose transporter subunit
YP_001783899.1	with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains
YP_001783900.1	PFAM: inner-membrane translocator; KEGG: ecc:c5092 D-allose transporter permease alsC
YP_001783901.1	PFAM: ribulose-phosphate 3-epimerase; KEGG: ecj:JW4046 allulose-6-phosphate 3-epimerase
YP_001783902.1	PFAM: ROK family protein; KEGG: ecp:ECP_4326 D-allose kinase
YP_001783903.1	TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: ribose/galactose isomerase; KEGG: llc:LACR_1638 galactose 6-phosphate isomerase
YP_001783904.1	heat shock protein involved in degradation of misfolded proteins
YP_001783905.1	heat shock protein involved in degradation of misfolded proteins
YP_001783906.1	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III
YP_001783907.1	PFAM: protein of unknown function DUF416; KEGG: hso:HS_1539 hypothetical protein
YP_001783908.1	PFAM: histone family protein DNA-binding protein; KEGG: hso:HS_1538 DNA-binding protein HU
YP_001783909.1	PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: hso:HS_1537 transcriptional regulator, DeoR family
YP_001783910.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_001783911.1	TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: hso:HS_1535 outer membrane lipoprotein 1 precursor
YP_001783912.1	PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_1534 D-methionine ABC transporter permease
YP_001783913.1	part of the metNIQ transporter for methionine
YP_001783914.1	Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate
YP_001783915.1	PFAM: protein of unknown function DUF1603; KEGG: hpy:HP1471 type IIS restriction enzyme R protein
YP_001783916.1	PFAM: glycerate kinase; KEGG: hso:HS_1524 glycerate kinase
YP_001783917.1	PFAM: gluconate transporter; citrate transporter; KEGG: hit:NTHI0171 hypothetical protein
YP_001783918.1	PFAM: sugar diacid recognition domain protein; KEGG: hso:HS_1521  sugar diacid utilization regulator
YP_001783919.1	KEGG: hso:HS_1452 hypothetical protein
YP_001783920.1	catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate
YP_001783921.1	PFAM: RbsD or FucU transport; KEGG: hso:HS_1450 fucose operon FucU protein
YP_001783922.1	TIGRFAM: L-fuculokinase; PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_1449 L-fuculokinase
YP_001783923.1	catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose
YP_001783924.1	TIGRFAM: L-fucose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_1447 L-fucose permease
YP_001783925.1	PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: hso:HS_1446 L-fucose operon activator
YP_001783926.1	2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate
YP_001783927.1	catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit
YP_001783928.1	PFAM: peptidase M23B; KEGG: hso:HS_1443 hypothetical protein
YP_001783929.1	PFAM: protein of unknown function DUF610 YibQ; KEGG: hso:HS_1442 hypothetical protein
YP_001783930.1	transcriptional repressor of asnA which codes for aspartate-ammonia ligase
YP_001783931.1	catalyzes the formation of asparagine from aspartate and ammonia
YP_001783932.1	PFAM: MgtC/SapB transporter; KEGG: hso:HS_1439 conserved hypothetical protein
YP_001783934.1	KEGG: hdu:HD1616  transposase
YP_001783935.1	KEGG: ngo:NGO0366 hypothetical protein
YP_001783936.1	TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: ngo:NGO0365 site-specific DNA-methyltransferase M.NgoVII
YP_001783937.1	KEGG: ngo:NGO0364 restriction endonuclease R.NgoVII
YP_001783938.1	KEGG: ngo:NGO0363  stress-sensitive restriction system protein
YP_001783939.1	PFAM: helix-turn-helix domain protein; KEGG: hdu:HD1613 hypothetical protein
YP_001783940.1	KEGG: hdu:HD1697 hypothetical protein
YP_001783942.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_001783943.1	binds single-stranded DNA at the primosome assembly site
YP_001783944.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_001783945.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_001783946.1	TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: hso:HS_1434  N-acyl-L-amino acid amidohydrolase
YP_001783947.1	PFAM: protein of unknown function DUF511; KEGG: pin:Ping_0238 hypothetical protein DUF511
YP_001783948.1	PFAM: N-6 DNA methylase; KEGG: cjr:CJE1195 type II restriction-modification enzyme
YP_001783949.1	KEGG: cje:Cj1051c restriction modification enzyme
YP_001783950.1	PFAM: sodium/calcium exchanger membrane region; KEGG: hso:HS_0343 calcium/proton antiporter
YP_001783951.1	PFAM: conserved hypothetical protein 698; KEGG: hso:HS_0344  membrane protein
YP_001783952.1	PFAM: PhoH family protein; KEGG: hso:HS_0345 PhoH-like ATP-binding protein
YP_001783953.1	PFAM: protein of unknown function UPF0054; KEGG: hso:HS_0346 conserved hypothetical protein
YP_001783954.1	PFAM: protein of unknown function DUF699 ATPase KEGG: hso:HS_0347  acetyltransferase
YP_001783955.1	KEGG: hso:HS_0347a hypothetical protein
YP_001783956.1	PFAM: carbon starvation protein CstA; KEGG: hso:HS_0348 carbon starvation protein A
YP_001783957.1	MraZ; UPF0040; crystal structure shows similarity to AbrB
YP_001783958.1	TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: hso:HS_0350 S-adenosyl-methyltransferase
YP_001783959.1	PFAM: cell division protein FtsL; KEGG: hso:HS_0351 cell division protein
YP_001783960.1	PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: hso:HS_0352 peptidoglycan glycosyltransferase (peptidoglycan synthetase)
YP_001783961.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
YP_001783962.1	TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: hso:HS_0354 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (MurF synthetase)
YP_001783963.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_001783964.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
YP_001783965.1	TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: hso:HS_0357 cell division protein
YP_001783966.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_001783967.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_001783968.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_001783969.1	PFAM: cell division protein FtsQ; polypeptide-transport-associated domain protein FtsQ-type; KEGG: hso:HS_0361 cell division protein
YP_001783970.1	PFAM: cell division protein FtsA; KEGG: hso:HS_0362 ATP-binding cell division protein
YP_001783971.1	TIGRFAM: cell division protein FtsZ; PFAM: Tubulin/FtsZ GTPase; Tubulin/FtsZ domain protein; KEGG: hso:HS_0363 cell division protein
YP_001783972.1	zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis
YP_001783973.1	TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; chorismate mutase; KEGG: hso:HS_0365 bifunctional P-protein/chorismate mutase
YP_001783974.1	PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: hso:HS_0366 DNA uptake lipoprotein
YP_001783975.1	responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA
YP_001783976.1	PFAM: protein of unknown function DUF152; KEGG: hso:HS_0368 conserved hypothetical protein
YP_001783977.1	TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; KEGG: hso:HS_0369 cysteine synthase
YP_001783978.1	role in sulfur assimilation
YP_001783979.1	interacts with cell division protein FitsZ and may be required to anchor septal ring structure
YP_001783980.1	ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence
YP_001783981.1	KEGG: msu:MS1887 hypothetical protein
YP_001783982.1	PFAM: ABC transporter; KEGG: vpa:VPA1495 ABC transporter ATP-binding protein
YP_001783983.1	PFAM: peptidase S24 S26A and S26B; KEGG: mgm:Mmc1_2924  phage repressor
YP_001783985.1	PFAM: Integrase catalytic region; MuA-transposase/repressor protein CI DNA-binding; transposase-like Mu; KEGG: ecs:ECs4945 phage transposase
YP_001783986.1	PFAM: helix-turn-helix domain protein; KEGG: nmc:NMC1048  phage transposase
YP_001783989.1	KEGG: hdu:HD0097 hypothetical protein
YP_001783991.1	KEGG: hdu:HD0100 hypothetical protein
YP_001783993.1	KEGG: hdu:HD0107 hypothetical protein
YP_001783994.1	KEGG: hdu:HD1519 hypothetical protein
YP_001783995.1	PFAM: protein of unknown function DUF1018; KEGG: hdu:HD0497 hypothetical protein
YP_001783997.1	KEGG: hdu:HD0500 hypothetical protein
YP_001783998.1	PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: Animal peptidoglycan recognition protein PGRP; KEGG: hdu:HD0112  N-acetylmuramoyl-L-alanine amidase
YP_001783999.1	KEGG: hdu:HD0503 hypothetical protein
YP_001784001.1	KEGG: nma:NMA1856 hypothetical protein
YP_001784002.1	KEGG: hdu:HD0507 hypothetical protein
YP_001784003.1	PFAM: protein of unknown function DUF1804; KEGG: hdu:HD0509 conserved  DNA-binding protein
YP_001784004.1	TIGRFAM: phage uncharacterized protein; KEGG: nma:NMA1313 hypothetical protein
YP_001784005.1	PFAM: protein of unknown function DUF935; KEGG: hdu:HD0514 hypothetical protein
YP_001784006.1	TIGRFAM: phage  head morphogenesis protein, SPP1 gp7 family; PFAM: phage  head morphogenesis protein SPP1 gp7; KEGG: hdu:HD0515 hypothetical protein
YP_001784007.1	TIGRFAM: phage virion morphogenesis protein; PFAM: phage virion morphogenesis ( tail completion) protein; KEGG: hin:HI1568 G protein
YP_001784008.1	KEGG: nme:NMB1098  I protein
YP_001784009.1	KEGG: hdu:HD0519 bacteriophage mu T protein homolog
YP_001784010.1	KEGG: hdu:HD0520 hypothetical protein
YP_001784011.1	PFAM: protein of unknown function DUF1320; KEGG: nme:NMB1101 hypothetical protein
YP_001784012.1	PFAM: Domain of unknown function DUF1834; KEGG: nme:NMB1102 hypothetical protein
YP_001784013.1	KEGG: dvu:DVU2715 hypothetical protein
YP_001784014.1	PFAM: bacteriophage Mu tail sheath family protein; KEGG: nme:NMB1104 phage sheath protein
YP_001784015.1	KEGG: nme:NMB1105 hypothetical protein
YP_001784017.1	KEGG: nme:NMB1108 hypothetical protein
YP_001784018.1	KEGG: nme:NMB1109  phage virion protein
YP_001784019.1	PFAM: bacteriophage Mu P family protein; KEGG: nma:NMA1320 hypothetical protein
YP_001784020.1	TIGRFAM: phage baseplate assembly protein V; PFAM: bacteriophage Mu Gp45 domain protein; KEGG: nma:NMA1321 hypothetical protein
YP_001784021.1	PFAM: phage GP46 family protein; KEGG: nma:NMA1322 hypothetical protein
YP_001784022.1	PFAM: Baseplate J family protein; KEGG: nma:NMA1323 hypothetical protein
YP_001784023.1	KEGG: nmc:NMC1057 hypothetical protein
YP_001784024.1	PFAM: phage tail fiber repeat 2 protein; phage Tail Collar domain protein; KEGG: hit:NTHI1857 probable tail fiber protein
YP_001784025.1	KEGG: hit:NTHI1553 hypothetical protein
YP_001784026.1	KEGG: hit:NTHI1554 hypothetical protein
YP_001784027.1	KEGG: mmy:MSC_0780  C5 methylase (MAV1virus-like)
YP_001784028.1	KEGG: hdu:HD0156 hypothetical protein
YP_001784029.1	KEGG: mxa:MXAN_1831 hypothetical protein
YP_001784031.1	PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: vch:VCA0977 ABC transporter ATP-binding protein
YP_001784032.1	PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hit:NTHI1288 oligopeptide transporter permease protein
YP_001784033.1	PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hin:HI1123 oligopeptide transporter permease protein
YP_001784034.1	PFAM: extracellular solute-binding protein family 5; KEGG: hit:NTHI1292 periplasmic oligopeptide-binding protein
YP_001784035.1	PFAM: extracellular solute-binding protein family 5; KEGG: hit:NTHI1292 periplasmic oligopeptide-binding protein
YP_001784036.1	PFAM: TrkA-N domain protein; KEGG: hso:HS_0375 K+ transporter
YP_001784037.1	TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: hso:HS_0376 cation transporter
YP_001784038.1	this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB
YP_001784039.1	TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter; KEGG: hso:HS_0378 gluconate permease
YP_001784040.1	Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate
YP_001784041.1	NAD-binding
YP_001784042.1	TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase; KEGG: hso:HS_0379 gluconokinase (gluconate kinase)
YP_001784043.1	TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: hso:HS_0380 conserved hypothetical protein
YP_001784044.1	PFAM: Domain of unknown function DUF1850; KEGG: hso:HS_0381 hypothetical protein
YP_001784045.1	TIGRFAM: TRAP transporter 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_0382 conserved integral membrane protein
YP_001784046.1	PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1085  large adhesin
YP_001784047.1	stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein
YP_001784048.1	PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA
YP_001784049.1	Represses a number of genes involved in the response to DNA damage
YP_001784050.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
YP_001784051.1	catalyzes the removal of an N-terminal amino acid from a peptide or arylamide
YP_001784052.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
YP_001784053.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
YP_001784054.1	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis
YP_001784055.1	catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis
YP_001784056.1	ATP-binding protein; required for proper cytochrome C maturation
YP_001784057.1	TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: hso:HS_0394 heme ABC transporter permease (heme exporter protein B)
YP_001784058.1	TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome C assembly protein; KEGG: hso:HS_0395 heme ABC transporter permease (heme exporter protein C)
YP_001784059.1	PFAM: Heme exporter protein D (CcmD); KEGG: hso:HS_0396 heme ABC transporter substrate-binding protein (heme exporter protein D)
YP_001784060.1	CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome C maturation system; periplasmic protein anchored to the inner membrane
YP_001784061.1	TIGRFAM: cytochrome C biogenesis protein CcmF; PFAM: cytochrome C assembly protein; KEGG: hso:HS_0398 cytochrome C biogenesis protein F
YP_001784062.1	TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: hso:HS_0399 thiol:disulfide interchange protein
YP_001784063.1	PFAM: cytochrome C biogenesis protein; KEGG: hso:HS_0400 cytochrome C biogenesis protein H
YP_001784064.1	KEGG: hso:HS_0401 cytochrome C biogenesis protein, with TPR repeats
YP_001784065.1	PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: hso:HS_0402 sensor histidine kinase
YP_001784066.1	KEGG: hso:HS_0403 hypothetical protein
YP_001784067.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
YP_001784068.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_001784069.1	KEGG: hso:HS_0406 hypothetical protein
YP_001784070.1	TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: hso:HS_0407 succinate-semialdehyde dehydrogenase (NAD(P)+)
YP_001784071.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
YP_001784072.1	PFAM: protein of unknown function UPF0126; KEGG: hso:HS_0409 hypothetical protein
YP_001784073.1	catalyzes the formation of thymidine 5'-phosphate from thymidine
YP_001784074.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_001784075.1	TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: hso:HS_0412 DNA processing chain A
YP_001784076.1	TIGRFAM:  methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: hso:HS_0413 conserved methylase
YP_001784077.1	TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase; KEGG: hso:HS_0414 cell division protein
YP_001784078.1	TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: hso:HS_0415 conserved membrane protein
YP_001784079.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_001784080.1	TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: hso:HS_0417 GTP-binding protein
YP_001784081.1	TIGRFAM: glutamine synthetase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: hso:HS_0418 glutamate--ammonia ligase (glutamine synthetase)
YP_001784082.1	catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon
YP_001784083.1	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
YP_001784084.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_001784085.1	KEGG: hso:HS_1709 transposase
YP_001784086.1	PFAM: glycoside hydrolase family 29 (alpha-L-fucosidase); KEGG: hso:HS_0435 alpha-L-fucosidase
YP_001784087.1	PFAM: transferrin binding protein; KEGG: hso:HS_0448 transferrin-binding protein
YP_001784088.1	TIGRFAM: TonB-dependent lactoferrin and transferrin receptors; TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0449 transferrin-binding protein A
YP_001784089.1	molecular chaperone
YP_001784090.1	KEGG: hso:HS_0454 hypothetical protein
YP_001784091.1	PFAM: 4'-phosphopantetheinyl transferase; KEGG: hso:HS_0455 4'-phosphopantetheinyl transferase family protein
YP_001784092.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_001784093.1	PFAM: type II secretion system protein; KEGG: hso:HS_0457 protein transporter
YP_001784094.1	PFAM: peptidase A24A prepilin type IV; KEGG: hso:HS_0458 prepilin peptidase
YP_001784095.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
YP_001784096.1	PFAM: protein of unknown function DUF329; KEGG: hso:HS_0460 hypothetical protein
YP_001784097.1	KEGG: hso:HS_0460a hypothetical protein
YP_001784098.1	TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: hso:HS_0461 D-alanine glycine permease
YP_001784099.1	TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: hso:HS_0462 ribosome-associated protein Y
YP_001784100.1	TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: hso:HS_0463 hypoxanthine phosphoribosyltransferase (HPRT)
YP_001784101.1	PFAM: manganese and iron superoxide dismutase; KEGG: hso:HS_0464 superoxide dismutase, manganese
YP_001784102.1	NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate
YP_001784103.1	catalyzes the formation of fumarate from aspartate
YP_001784104.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
YP_001784105.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_001784106.1	when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis
YP_001784107.1	KEGG: hso:HS_0470 hypothetical protein
YP_001784108.1	KEGG: hso:HS_0471 hypothetical protein
YP_001784109.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_001784110.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_001784111.1	TIGRFAM: UbiD family decarboxylase; PFAM: carboxylyase-related protein; KEGG: hso:HS_0474 3-octaprenyl-4-hydroxybenzoate carboxy-lyase (polyprenyl p-hydroxybenzoate decarboxylase)
YP_001784112.1	catalyzes the formation of L-homocysteine from cystathionine
YP_001784113.1	PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: hso:HS_0476 AhpC/TSA family protein
YP_001784114.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_001784115.1	PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_1282 permease,  major facilitator superfamily
YP_001784116.1	KEGG: hso:HS_1281  permease
YP_001784117.1	in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane
YP_001784118.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
YP_001784119.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
YP_001784120.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
YP_001784121.1	lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_001784122.1	PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: hso:HS_1275  FAD flavoprotein oxidase
YP_001784123.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1274 ABC transporter ATP-binding protein
YP_001784124.1	PFAM: binding-protein-dependent transporters inner membrane component; ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: hso:HS_1273 ABC transporter permease/ATP-binding protein
YP_001784125.1	PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_1272 ABC transporter permease
YP_001784126.1	PFAM: extracellular solute-binding protein family 5; KEGG: hso:HS_1271 ABC transporter periplasmic binding protein
YP_001784127.1	catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate
YP_001784128.1	unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity
YP_001784129.1	PFAM: thioesterase superfamily protein; KEGG: hso:HS_1268  acyl-CoA hydrolase
YP_001784130.1	Involved in cell division; probably involved in intracellular septation
YP_001784131.1	KEGG: hso:HS_1266  membrane protein
YP_001784132.1	binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB
YP_001784133.1	KEGG: hso:HS_1263 Haemophilus-specific protein, uncharacterized
YP_001784134.1	PFAM: filamentation induced by cAMP protein Fic; KEGG: hso:HS_1262 hypothetical protein
YP_001784135.1	KEGG: hso:HS_1261 hypothetical protein
YP_001784136.1	KEGG: hso:HS_1374 Haemophilus-specific protein, uncharacterized
YP_001784137.1	TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: hpy:HP1121 cytosine specific DNA methyltransferase
YP_001784138.1	KEGG: hpj:jhp1049 hypothetical protein
YP_001784139.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_001784140.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_001784141.1	Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis
YP_001784142.1	KEGG: hit:NTHI0936  HTH-type transcriptional regulator
YP_001784143.1	TIGRFAM: 3-oxoacid CoA-transferase, subunit alpha; KEGG: hit:NTHI0935 acetate CoA-transferase subunit alpha
YP_001784144.1	TIGRFAM: 3-oxoacid CoA-transferase subunit beta; KEGG: hit:NTHI0934 acetate CoA-transferase subunit beta
YP_001784145.1	KEGG: hin:HI0772 short-chain fatty acids transporter
YP_001784146.1	TIGRFAM: acetyl-CoA acetyltransferase; KEGG: ecp:ECP_2268 acetyl-CoA acetyltransferase
YP_001784147.1	TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: csa:Csal_1825 3-hydroxybutyrate dehydrogenase
YP_001784148.1	PFAM: gluconate transporter; citrate transporter; KEGG: pcr:Pcryo_1595 GntP family transporter
YP_001784149.1	involved in transport of zinc(II) with ZnuA and C
YP_001784150.1	PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: hso:HS_1255 hypothetical protein
YP_001784151.1	membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues
YP_001784152.1	catalyzes phosphorylation of fructose; cytosolic enzyme
YP_001784153.1	PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pmu:PM1376 hypothetical Rhizobium sp.
YP_001784154.1	PFAM: PfkB domain protein; KEGG: pmu:PM1372 sugar kinase
YP_001784155.1	TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; KEGG: pmu:PM1373 fructose-bisphosphate aldolase
YP_001784156.1	PFAM: protein of unknown function DUF1498; KEGG: pmu:PM1374 unknown
YP_001784157.1	PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: pmu:PM1377 D-ribose binding periplasmic protein precursor
YP_001784158.1	PFAM: inner-membrane translocator; KEGG: pmu:PM1378 ribose ABC transporter permease
YP_001784159.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pmu:PM1379 ribose ABC transporter ATP-binding protein
YP_001784160.1	SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: pmu:PM1380 hybrid histidine protein kinase-phosphate acceptor regulatory protein
YP_001784161.1	TIGRFAM: PTS system, mannitol-specific IIC subunit; KEGG: hso:HS_1252 mannitol-specific IIABC component, PTS system
YP_001784162.1	KEGG: hso:HS_1251 mannitol 1-phosphate 5-dehydrogenase
YP_001784163.1	Acts as a repressor of the mtlAD operon
YP_001784164.1	TIGRFAM: UDP-N-acetylmuramate; KEGG: hso:HS_1249 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamayl-medo- diaminopimelate
YP_001784165.1	catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate
YP_001784166.1	alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family
YP_001784167.1	TIGRFAM: anaerobic c4-dicarboxylate antiporter, DcuC family; PFAM: C4-dicarboxylate anaerobic carrier; citrate transporter; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_1244 permease,  C4-dicarboxylate transporter
YP_001784168.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_001784169.1	TIGRFAM: signal peptidase I; PFAM: peptidase S24 S26A and S26B; KEGG: hso:HS_1241 signal peptidase I
YP_001784170.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
YP_001784171.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_001784172.1	catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate
YP_001784173.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_001784174.1	synthesizes RNA primers at the replication forks
YP_001784175.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria
YP_001784176.1	PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1616  large adhesin
YP_001784177.1	PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: hso:HS_1233 membrane protein
YP_001784178.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_001784179.1	KEGG: hso:HS_1231 hypothetical protein
YP_001784181.1	KEGG: hso:HS_1230 hypothetical protein
YP_001784182.1	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway
YP_001784183.1	KEGG: hso:HS_1709 transposase
YP_001784184.1	KEGG: hso:HS_1228 integrase
YP_001784185.1	KEGG: hso:HS_1227 hypothetical protein
YP_001784186.1	catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate
YP_001784187.1	PFAM: flavin reductase domain protein FMN-binding; KEGG: hso:HS_1225  flavin:NADH reductase
YP_001784188.1	KEGG: rba:RB9243 hypothetical protein- glycosyltransferase
YP_001784189.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_001784190.1	TIGRFAM:  methyltransferase; PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: hso:HS_1222  SAM-dependent methyltransferase
YP_001784191.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
YP_001784192.1	PFAM: phage integrase family protein; KEGG: ecp:ECP_0274 phage integrase
YP_001784193.1	TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: hso:HS_1422 DNA-cytosine methyltransferase
YP_001784194.1	KEGG: hdu:HD0960 hypothetical protein
YP_001784195.1	KEGG: hso:HS_1421 hypothetical protein
YP_001784196.1	KEGG: sit:TM1040_1688 hypothetical protein
YP_001784197.1	KEGG: hso:HS_1418 Haemophilus-specific protein, uncharacterized
YP_001784198.1	KEGG: hso:HS_1417 Haemophilus-specific protein, uncharacterized
YP_001784199.1	KEGG: hso:HS_1416 Haemophilus-specific protein, uncharacterized
YP_001784200.1	KEGG: ecv:APECO1_4215  antirepressor protein
YP_001784201.1	KEGG: cjr:CJE1430 RloG protein
YP_001784203.1	KEGG: ecp:ECP_4545 hypothetical protein
YP_001784204.1	KEGG: sgl:SG1183 hypothetical protein
YP_001784205.1	KEGG: bbr:BB3533 hypothetical protein
YP_001784206.1	PFAM: KilA domain protein; KEGG: vvu:VV2_0650 hypothetical protein
YP_001784207.1	KEGG: xft:PD1061 DNA-damage-inducible protein D
YP_001784208.1	KEGG: hit:NTHI1717 hypothetical protein
YP_001784209.1	PFAM: protein of unknown function DUF1508; KEGG: deh:cbdb_A1247 hypothetical protein
YP_001784210.1	TIGRFAM: Addiction module killer protein HI1419; PFAM: protein of unknown function DUF891; KEGG: hin:HI1419 hypothetical protein
YP_001784211.1	TIGRFAM: Addiction module antidote protein HI1420; PFAM: helix-turn-helix domain protein; KEGG: hin:HI1420 hypothetical protein
YP_001784212.1	KEGG: bam:Bamb_0901 hypothetical protein
YP_001784213.1	PFAM: peptidase S24 S26A and S26B; SMART: helix-turn-helix domain protein; KEGG: bbr:BB1678  phage repressor
YP_001784214.1	KEGG: ecs:ECs1942 regulatory protein
YP_001784215.1	KEGG: hso:HS_1403 hypothetical protein
YP_001784216.1	KEGG: hso:HS_1402 hypothetical protein
YP_001784217.1	PFAM: replication P family protein; KEGG: hso:HS_1401  replication protein P
YP_001784218.1	TIGRFAM: phage N-6-adenine-methyltransferase; PFAM: DNA N-6-adenine-methyltransferase; KEGG: hso:HS_1400  DNA methylase
YP_001784219.1	KEGG: hso:HS_1399 hypothetical protein
YP_001784220.1	PFAM: BRO domain protein; KEGG: hso:HS_1398  prophage antirepressor
YP_001784221.1	PFAM: protein of unknown function UPF0150; KEGG: hso:HS_1396 hypothetical protein
YP_001784222.1	PFAM: YcfA family protein; KEGG: hso:HS_1395 hypothetical protein
YP_001784223.1	PFAM: bacteriophage Lambda NinG family protein; KEGG: hso:HS_1394 NinG recombination protein
YP_001784224.1	KEGG: nmc:NMC0837 hypothetical protein
YP_001784225.1	KEGG: hso:HS_1389 Haemophilus-specific protein, uncharacterized
YP_001784226.1	PFAM: glycoside hydrolase family 24; KEGG: hso:HS_1388 lysozyme,  phage-related lysozyme
YP_001784227.1	KEGG: hso:HS_1387 hypothetical protein
YP_001784228.1	KEGG: hso:HS_1386  terminase small subunit
YP_001784229.1	KEGG: hso:HS_1385 hypothetical protein
YP_001784230.1	KEGG: hso:HS_1384 Haemophilus-specific protein, uncharacterized
YP_001784232.1	KEGG: hso:HS_1382  phage-related protein
YP_001784233.1	KEGG: ecv:APECO1_4215  antirepressor protein
YP_001784234.1	KEGG: hso:HS_1381 hypothetical protein
YP_001784235.1	KEGG: hso:HS_1381 hypothetical protein
YP_001784236.1	KEGG: hso:HS_1380  transcription regulator
YP_001784237.1	KEGG: hso:HS_1379 Haemophilus-specific protein, uncharacterized
YP_001784238.1	KEGG: hso:HS_1378 hypothetical protein
YP_001784239.1	KEGG: hso:HS_1377 hypothetical protein
YP_001784240.1	KEGG: hso:HS_1376 Haemophilus-specific protein, uncharacterized
YP_001784241.1	KEGG: hso:HS_1375 Haemophilus-specific protein, uncharacterized
YP_001784242.1	KEGG: hso:HS_1373 Haemophilus-specific protein, uncharacterized
YP_001784243.1	KEGG: hso:HS_1372  phage-related tail fiber protein
YP_001784244.1	PFAM: helix-turn-helix domain protein; KEGG: xfa:XF0534 hypothetical protein
YP_001784245.1	KEGG: tde:TDE1648 hypothetical protein
YP_001784246.1	KEGG: nme:NMB1119 hypothetical protein
YP_001784247.1	KEGG: hso:HS_1370 hypothetical protein
YP_001784248.1	KEGG: hso:HS_1369 hypothetical protein
YP_001784249.1	KEGG: hso:HS_1368 Haemophilus-specific protein, uncharacterized
YP_001784250.1	KEGG: hso:HS_1367 Haemophilus-specific protein, uncharacterized
YP_001784251.1	KEGG: hso:HS_1366 Haemophilus-specific protein, uncharacterized
YP_001784252.1	KEGG: hso:HS_1365 Haemophilus-specific protein, uncharacterized
YP_001784253.1	PFAM: phage virion morphogenesis ( tail completion) protein; KEGG: hit:NTHI1873 probable bacteriophage tail completion protein gpS homolog
YP_001784255.1	KEGG: hin:HI1501 hypothetical protein HI1501
YP_001784256.1	acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA
YP_001784257.1	catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose
YP_001784258.1	PFAM: arsenate reductase; KEGG: hso:HS_0577  arsenate reductase
YP_001784259.1	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.
YP_001784260.1	PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: hso:HS_0579 D-alanyl-D-alanine carboxypeptidase-related protein
YP_001784261.1	PFAM: NUDIX hydrolase; KEGG: hso:HS_0580 ADP-ribose diphosphatase
YP_001784262.1	PFAM: metallophosphoesterase; Calcineurin phosphoesterase domain protein; KEGG: hso:HS_0581 3',5'-cyclic-nucleotide phosphodiesterase
YP_001784263.1	PFAM: TonB-dependent receptor; KEGG: hso:HS_0582 transferrin binding protein A
YP_001784264.1	PFAM: TonB-dependent receptor plug; KEGG: hso:HS_0582 transferrin binding protein A
YP_001784265.1	PFAM: inner-membrane translocator; KEGG: hso:HS_0584 D-xylose ABC transporter permease
YP_001784266.1	with XylFH is part of the high affinity xylose ABC transporter
YP_001784267.1	periplasmic substrate-binding component of the ATP-dependent xylose transporter; high affinity
YP_001784268.1	catalyzes the interconversion of D-xylose to D-xylulose
YP_001784269.1	TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_0588 xylulokinase (xylulose kinase)
YP_001784270.1	PFAM: Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0602  adhesin
YP_001784271.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0590 peptide ABC transporter ATP-binding protein
YP_001784272.1	TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: hso:HS_0591 peptide ABC transporter ATP-binding protein
YP_001784273.1	PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0592 peptide ABC transporter permease
YP_001784274.1	PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0593 peptide ABC transporter permease
YP_001784275.1	PFAM: extracellular solute-binding protein family 5; KEGG: hso:HS_0594 peptide ABC transporter periplasmic-binding protein
YP_001784276.1	PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: hso:HS_0595 conserved hypothetical protein
YP_001784277.1	PFAM: conserved hypothetical protein 1620; KEGG: hso:HS_0596 hypothetical protein
YP_001784278.1	functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase
YP_001784279.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_001784280.1	KEGG: nmc:NMC0772  type II restriction endonuclease
YP_001784281.1	TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: nmc:NMC0771  modification methylase
YP_001784282.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_001784283.1	TIGRFAM: AmpG-related permease; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_0600 AmpG protein
YP_001784284.1	PFAM: xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: hso:HS_0601 conserved permease, xanthine/uracil family
YP_001784285.1	PFAM: Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0602  adhesin
YP_001784286.1	3'-5' exonuclease of DNA polymerase III
YP_001784287.1	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
YP_001784288.1	TIGRFAM: mannose-6-phosphate isomerase, class I; KEGG: hso:HS_0605 mannose-6-phosphate isomerase (phosphomannose isomerase)
YP_001784289.1	KEGG: hso:HS_0606 hypothetical protein
YP_001784290.1	hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel
YP_001784291.1	TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; KEGG: hso:HS_0608 protein-N(pi)-phosphohistidine-sugar phosphotransferase (mannose-specific phosphotransferase system IIC component)
YP_001784292.1	TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PTS system, mannose/fructose/sorbose family, IIsubunit alpha; KEGG: hso:HS_0609 protein-N(pi)-phosphohistidine-sugar phosphotransferase (phosphotransferase system mannose/fructose-specific IIA component)
YP_001784293.1	PFAM: protein of unknown function DUF496; KEGG: hso:HS_0610 hypothetical protein
YP_001784294.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine
YP_001784295.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
YP_001784296.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
YP_001784297.1	TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: hso:HS_0614 membrane fusion protein
YP_001784298.1	PFAM: acriflavin resistance protein; KEGG: hso:HS_0615 cation/multidrug efflux protein
YP_001784299.1	catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA
YP_001784300.1	SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis
YP_001784301.1	TIGRFAM: isochorismate synthase; PFAM: anthranilate synthase component I and chorismate binding protein; KEGG: hso:HS_0618 isochorismate synthase
YP_001784302.1	broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor
YP_001784303.1	Multifunctional regulator of fatty acid metabolism
YP_001784304.1	disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein
YP_001784305.1	KEGG: pmu:PM1140 glycosyl transferase
YP_001784306.1	KEGG: hdu:HD0466 lipooligosaccharide N-acetylglucosamine glycosyltransferase
YP_001784307.1	PFAM: glycosyl transferase family 25; KEGG: hit:NTHI0677 UDP-Gal--lipooligosaccharide galactosyltransferase
YP_001784308.1	PFAM: glycosyl transferase family 25; KEGG: hdu:HD0472 lipooligosaccharide galactosyltransferase II
YP_001784309.1	PFAM: glycosyl transferase family 25; KEGG: hso:HS_0638 Lob1 protein
YP_001784310.1	Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import
YP_001784311.1	PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0640 Fe3+ ABC transporter permease
YP_001784312.1	PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_0641 Fe3+ ABC transporter iron-binding protein
YP_001784313.1	PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_0643 Fe3+ ABC transporter iron-binding protein
YP_001784314.1	functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor
YP_001784315.1	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis
YP_001784316.1	KEGG: hso:HS_0646 hypothetical protein
YP_001784317.1	PFAM: sodium symporter; KEGG: hso:HS_0647 sodium-dependent transporter
YP_001784318.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
YP_001784319.1	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor
YP_001784320.1	catalyzes the phosphorylation of NAD to NADP
YP_001784321.1	TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: hso:HS_0651 DNA repair protein
YP_001784322.1	PFAM: sodium/hydrogen exchanger; KEGG: hso:HS_0652 Na+/H+ antiporter
YP_001784323.1	PFAM: endoribonuclease L-PSP; KEGG: hso:HS_0653  translation inhibitor of mRNA
YP_001784324.1	KEGG: hso:HS_0654 hypothetical protein
YP_001784325.1	TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; KEGG: hso:HS_0655 ribosomal protein S6 modification protein
YP_001784326.1	transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate
YP_001784327.1	PFAM: protein of unknown function DUF343; KEGG: hso:HS_0657 hypothetical protein
YP_001784328.1	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS
YP_001784329.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_001784330.1	PFAM: hypothetical protein?; KEGG: hso:HS_0660  membrane protein
YP_001784331.1	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
YP_001784332.1	PFAM: short-chain dehydrogenase/reductase SDR; KEGG: hso:HS_0662 enoyl-[acyl-carrier-protein] reductase (NADH)
YP_001784333.1	PFAM: protein of unknown function DUF34; KEGG: hso:HS_0663 hypothetical protein
YP_001784334.1	catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules
YP_001784335.1	FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_001784336.1	TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: hso:HS_1101 ammonium transporter
YP_001784337.1	3'-5' exoribonuclease specific for small oligoribonuclotides
YP_001784338.1	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity
YP_001784339.1	TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: hso:HS_1098 phosphocarrier protein HPr
YP_001784340.1	phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transporter
YP_001784341.1	functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose
YP_001784342.1	E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC
YP_001784343.1	TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: hso:HS_1094 pyruvate dehydrogenase, E2 complex
YP_001784344.1	E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_001784345.1	KEGG: hso:HS_1092 ImpA protein
YP_001784346.1	involved in the import of serine and threonine coupled with the import of sodium
YP_001784347.1	When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription
YP_001784348.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_001784349.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_001784350.1	PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: hso:HS_1087 peptidyl-prolyl cis-trans isomerase D
YP_001784351.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_001784352.1	PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1085  large adhesin
YP_001784353.1	TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: hso:HS_1153 phosphatidylglycerophosphate synthase
YP_001784354.1	PFAM: protein of unknown function DUF455; KEGG: hso:HS_1152 hypothetical protein
YP_001784355.1	TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: hso:HS_1151 hypothetical protein
YP_001784356.1	in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c
YP_001784357.1	in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c
YP_001784358.1	TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: hso:HS_1148 thioredoxin reductase
YP_001784359.1	activates pyruvate formate-lyase 1 under anaerobic conditions
YP_001784360.1	catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources
YP_001784361.1	PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; KEGG: hso:HS_1145 tagatose 6-phosphate kinase
YP_001784362.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_001784363.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_001784364.1	TIGRFAM: PTS system, galactitol-specific IIC subunit; PFAM: PTS system Galactitol-specific IIC component; KEGG: hso:HS_1142 PTS system, galactitol-specific IIC component
YP_001784365.1	Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate
YP_001784366.1	PFAM: regulatory protein GntR HTH; regulatory protein DeoR; hypothetical protein; regulatory protein DeoR; KEGG: hso:HS_1140 galactitol utilization operon repressor
YP_001784367.1	KEGG: hso:HS_1139 hypothetical protein
YP_001784368.1	PFAM: protein of unknown function DUF692; Xylose isomerase domain protein TIM barrel; KEGG: hso:HS_1138 hypothetical protein
YP_001784369.1	KEGG: pmu:PM0212 hypothetical HI1601
YP_001784370.1	PFAM: DoxX family protein; KEGG: hso:HS_1137 hypothetical protein
YP_001784371.1	TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL; KEGG: hso:HS_1136 formate acetyltransferase
YP_001784372.1	PFAM: formate/nitrite transporter; KEGG: hso:HS_1135 formate transporter
YP_001784373.1	PFAM: histidine triad (HIT) protein; KEGG: hso:HS_1134 HIT-like protein
YP_001784374.1	KEGG: hso:HS_1133 hypothetical protein
YP_001784375.1	hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
YP_001784376.1	PFAM: protein of unknown function DUF1706; KEGG: hso:HS_1131 hypothetical protein
YP_001784377.1	MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor
YP_001784378.1	binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA
YP_001784379.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrsubunit betas scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_001784380.1	functions in MreBCD complex in some organisms
YP_001784381.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
YP_001784382.1	PFAM: Rod shape-determining protein MreD; KEGG: hso:HS_1125 rod shape-determining protein
YP_001784383.1	PFAM: sporulation domain protein; KEGG: hso:HS_1124  cell division protein
YP_001784384.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
YP_001784385.1	functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era
YP_001784386.1	KEGG: vvu:VV2_0681 hypothetical protein
YP_001784387.1	PFAM: carboxymuconolactone decarboxylase; KEGG: mth:MTH234 gamma-carboxymuconolactone decarboxylase
YP_001784388.1	PFAM: major facilitator superfamily MFS_1; KEGG: vvu:VV2_0680 permease of the major facilitator superfamily
YP_001784389.1	PFAM: UspA domain protein; KEGG: hso:HS_1121 universal stress protein A
YP_001784390.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001784391.1	PFAM: carbon storage regulator; KEGG: hit:NTHI0977 carbon storage regulator homolog
YP_001784392.1	PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: hso:HS_1118 phosphomannomutase
YP_001784393.1	TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: nucleotidyl transferase; KEGG: hso:HS_1117 UTP--glucose-1-phosphate uridylyltransferase
YP_001784394.1	TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: hso:HS_1115 DNA adenine methylase
YP_001784395.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
YP_001784396.1	catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis
YP_001784397.1	TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: hso:HS_1112 competence protein E
YP_001784398.1	KEGG: hso:HS_1111 competence protein C
YP_001784399.1	PFAM: fimbrial assembly family protein; KEGG: hso:HS_1110 competence protein B
YP_001784400.1	KEGG: hso:HS_1109 competence protein A
YP_001784401.1	TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: hso:HS_1108 penicillin-binding protein 1A
YP_001784402.1	PFAM: protein of unknown function DUF519; KEGG: hso:HS_1107 conserved hypothetical protein
YP_001784403.1	catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense
YP_001784404.1	Stimulates the elongation of poly(A) tails
YP_001784405.1	PFAM: GTP-binding protein HSR1-related; KEGG: hso:HS_1104 GTP-binding protein HflX
YP_001784406.1	PFAM: sigma-54 factor interaction domain-containing protein; KEGG: hso:HS_1103 transcriptional regulatory protein
YP_001784407.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
YP_001784408.1	KEGG: hso:HS_0669 Haemophilus-specific protein, uncharacterized
YP_001784409.1	PFAM: helix-turn-helix domain protein; KEGG: hso:HS_0670  transcriptional regulator
YP_001784410.1	catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis
YP_001784411.1	TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: hso:HS_0672 phosphoribosylaminoimidazole carboxylase (AIR carboxylase)
YP_001784412.1	regulates genes involved in glucitol utilization
YP_001784413.1	TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; KEGG: hso:HS_0674 conserved phosphatase
YP_001784414.1	regulator for glucitol utilization
YP_001784415.1	catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate
YP_001784416.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_001784417.1	TIGRFAM: PTS system, glucitol/sorbitol-specific, IIBC subunit; PFAM: Sorbitol phosphotransferase protein II domain protein; KEGG: hso:HS_0678 PTS system, glucitol/sorbitol-specific IIBC component
YP_001784418.1	TIGRFAM: PTS system, glucitol/sorbitol-specific, IIC subunit; PFAM: PTS system protein II sorbitol-specific factor; KEGG: hso:HS_0679 PTS system, glucitol/sorbitol-specific IIC2 component
YP_001784419.1	KEGG: fnu:FN0131 hemolysin activator protein precursor
YP_001784420.1	TIGRFAM: filamentous haemagglutinin family outer membrane protein; PFAM: filamentous haemagglutinin domain protein; KEGG: fnu:FN1817 hemolysin
YP_001784421.1	TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: hso:HS_0680 VisC protein, monooxygenase family
YP_001784422.1	TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; 2-polyprenyl-6-methoxyphenol 4-hydroxylase; PFAM: monooxygenase FAD-binding; KEGG: hso:HS_0681 2-octaprenyl-6-methoxyphenol hydroxylase
YP_001784423.1	PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; KEGG: hso:HS_0682 Xaa-Pro aminopeptidase (proline aminopeptidase P)
YP_001784424.1	the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown
YP_001784425.1	PFAM: protein of unknown function DUF710; KEGG: hso:HS_0684 hypothetical protein
YP_001784426.1	PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: hso:HS_0685  5-formyltetrahydrofolate cyclo-ligase
YP_001784427.1	KEGG: hso:HS_0686  AphA-like regulator
YP_001784428.1	catalyzes the formation of serine from O-phosphoserine
YP_001784429.1	nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription
YP_001784430.1	TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: hso:HS_0689 TonB protein
YP_001784431.1	TIGRFAM: TonB system transporter ExbD type-2; PFAM: biopolymertransporter ExbD/TolR; KEGG: hso:HS_0690 biopolymer transport protein
YP_001784432.1	TIGRFAM: TonB-system energizer ExbB type-2; PFAM: MotA/TolQ/ExbB proton channel; KEGG: hso:HS_0691 biopolymer transporter
YP_001784433.1	catalyzes the formation of arginine from (N-L-arginino)succinate
YP_001784434.1	RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease
YP_001784435.1	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); defense mechanism against a harmful effect of D-tyrosine
YP_001784436.1	catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid
YP_001784437.1	PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: hso:HS_0696  RpiR family transcriptional regulator
YP_001784438.1	PFAM: conserved hypothetical protein 22; KEGG: hso:HS_0697 hypothetical protein
YP_001784439.1	catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein
YP_001784440.1	Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate
YP_001784441.1	KEGG: hso:HS_0700  N-acylneuraminate cytidylyltransferase
YP_001784442.1	TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_0701  TRAP dicarboxylate transporter periplasmic component
YP_001784443.1	TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: tripartite ATP-independent periplasmic transporter DctQ component; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_0702  TRAP dicarboxylate transporter permease
YP_001784444.1	PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; SMART: KH domain protein; KEGG: hso:HS_0703 polynucleotide phosphorylase
YP_001784445.1	PFAM: helicase; DbpA RNA-binding domain protein; DEAD/DEAH box helicase; SMART: DEAD-like helicases; KEGG: hso:HS_0704 ATP-dependent RNA helicase
YP_001784446.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_001784447.1	PFAM: acylneuraminate cytidylyltransferase; KEGG: hso:HS_0706 CMP-N-acetylneuraminic acid synthetase
YP_001784448.1	TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: hso:HS_0707 dTDP-D-glucose 4,6-dehydratase
YP_001784449.1	TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: hso:HS_0708 L-lactate permease
YP_001784450.1	PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: hso:HS_0709 hypothetical protein
YP_001784451.1	TIGRFAM: iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF162; KEGG: hso:HS_0710 hypothetical protein
YP_001784452.1	PFAM: protein of unknown function DUF162; KEGG: hso:HS_0711 conserved hypothetical protein
YP_001784453.1	two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm
YP_001784454.1	PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: hso:HS_0713 aerobic respiration control protein
YP_001784455.1	catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA
YP_001784456.1	TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: hso:HS_0715 ribonuclease E
YP_001784457.1	has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair
YP_001784458.1	TIGRFAM: ATP-dependent DNA helicase Rep; PFAM: UvrD/REP helicase; KEGG: hso:HS_0719 ATP-dependent DNA helicase
YP_001784459.1	PFAM: phage integrase family protein; KEGG: hso:HS_1220 integrase
YP_001784460.1	KEGG: hso:HS_1219 Haemophilus-specific protein, uncharacterized
YP_001784461.1	PFAM: bacteriophage replication gene A; KEGG: spt:SPA2623  phage gene
YP_001784465.1	KEGG: ecp:ECP_1147 hypothetical protein
YP_001784466.1	PFAM: helix-turn-helix domain protein; peptidase S24 S26A and S26B; bacteriophage CI repressor; KEGG: spt:SPA2414 transcriptional activator-regulatory protein
YP_001784467.1	PFAM: phage late control D family protein; KEGG: stt:t3444  regulator of late gene expression
YP_001784468.1	PFAM: phage P2 GpU family protein; KEGG: sgl:SG1860  phage tail protein
YP_001784469.1	PFAM: phage tail E family protein; KEGG: rsp:RSP_3353 phage related tail protein
YP_001784470.1	PFAM: phage major tail tube protein; KEGG: xcc:XCC2989 phage-related tail protein
YP_001784471.1	PFAM: phage tail sheath protein; KEGG: yps:YPTB1841  bacteriophage P2 tail sheath protein
YP_001784472.1	PFAM: protein of unknown function DUF172; KEGG: aeh:Mlg_1787 prevent-host-death family protein
YP_001784473.1	TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin Txe/YoeB; KEGG: aeh:Mlg_1786 addiction module toxin, Txe/YoeB family
YP_001784475.1	KEGG: msu:MS0077 hypothetical protein
YP_001784476.1	KEGG: nme:NMB1119 hypothetical protein
YP_001784477.1	KEGG: tde:TDE1648 hypothetical protein
YP_001784478.1	KEGG: xfa:XF0534 hypothetical protein
YP_001784479.1	PFAM: phage tail fiber repeat 2 protein; phage Tail Collar domain protein; KEGG: nme:NMB1115  tail fibre protein
YP_001784480.1	TIGRFAM: phage tail protein I; KEGG: hit:NTHI1858 predicted bacteriophage P2-related tail formation protein gpI
YP_001784481.1	PFAM: Baseplate J family protein; KEGG: hit:NTHI1860 predicted phage-related baseplate assembly protein
YP_001784482.1	PFAM: GPW/gp25 family protein; KEGG: hit:NTHI1861 predicted baseplate assembly protein W
YP_001784483.1	PFAM: phage baseplate assembly protein V; KEGG: hit:NTHI1862 predicted phage P2-like baseplate assembly protein
YP_001784485.1	KEGG: plu:plu2305 hypothetical protein
YP_001784486.1	TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: csa:Csal_1375 phage tail tape measure protein TP901, core region
YP_001784487.1	TIGRFAM: phage virion morphogenesis protein; PFAM: phage virion morphogenesis ( tail completion) protein; KEGG: hit:NTHI1873 probable bacteriophage tail completion protein gpS homolog
YP_001784488.1	PFAM: P2 phage tail completion R family protein; KEGG: yps:YPTB1850 gpR [Enterobacteria phage P2]
YP_001784490.1	PFAM: glycoside hydrolase family 24; KEGG: hso:HS_1388 lysozyme,  phage-related lysozyme
YP_001784491.1	KEGG: hit:NTHI1881 hypothetical protein
YP_001784492.1	PFAM: phage tail X family protein; KEGG: hit:NTHI1882 hypothetical protein
YP_001784493.1	PFAM: phage head completion; KEGG: hit:NTHI1883 hypothetical protein
YP_001784494.1	PFAM: phage small terminase subunit; KEGG: hit:NTHI1884 predicted terminase, endonuclease subunit
YP_001784495.1	TIGRFAM: phage major capsid protein, P2 family; PFAM: phage major capsid protein P2; KEGG: hit:NTHI1885 predicted major capsid protein
YP_001784496.1	PFAM: phage capsid scaffolding; KEGG: hit:NTHI1887 predicted capsid scaffolding protein
YP_001784497.1	PFAM:  terminase ATPase; KEGG: hit:NTHI1888 terminase, ATPase
YP_001784498.1	TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; PFAM: TonB-dependent receptor; KEGG: hit:NTHI0782 hemoglobin-haptoglobin binding protein B
YP_001784499.1	PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: hso:HS_0722 heme binding protein
YP_001784500.1	PFAM: protein of unknown function DUF1008; KEGG: hso:HS_0723 HugX protein
YP_001784501.1	Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit
YP_001784502.1	KEGG: hso:HS_0725 cell division protein; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; ATPase AAA central domain protein; peptidase M41 FtsH extracellular; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA
YP_001784503.1	PFAM: LicD family protein; KEGG: hso:HS_0727 lipopolysaccharide cholinephosphotransferase
YP_001784504.1	KEGG: hso:HS_0728 hemin receptor, outer membrane protein
YP_001784505.1	KEGG: spd:SPD_0914 23S rRNA (uracil-5-)-methyltransferase RumA
YP_001784506.1	KEGG: sha:SH2379 hypothetical protein
YP_001784507.1	KEGG: sav:SAV0404 hypothetical protein
YP_001784508.1	KEGG: dar:Daro_1916  nucleotide-binding protein containing TIR-like domain
YP_001784509.1	KEGG: spi:MGAS10750_Spy1685 hypothetical protein
YP_001784510.1	KEGG: spi:MGAS10750_Spy1699 hypothetical protein
YP_001784513.1	KEGG: neu:NE2094 hypothetical protein
YP_001784515.1	PFAM: protein of unknown function DUF87; KEGG: neu:NE2095 hypothetical protein
YP_001784516.1	PFAM: Relaxase/mobilization nuclease family protein; KEGG: spi:MGAS10750_Spy1708 relaxase
YP_001784517.1	PFAM: regulatory protein TetR; KEGG: tde:TDE0246 TetR family transcriptional regulator
YP_001784518.1	KEGG: tde:TDE0245 ABC transporter permease/ATP-binding protein protein
YP_001784519.1	KEGG: tde:TDE0244 ABC transporter permease/ATP-binding protein protein
YP_001784520.1	TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; KEGG: hso:HS_0729 dihydropteroate synthase
YP_001784521.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_001784522.1	TIGRFAM: phosphohistidine phosphatase SixA; PFAM: phosphoglycerate mutase; KEGG: hso:HS_0731 phosphohistidine phosphatase
YP_001784523.1	PFAM: Auxin Efflux Carrier; KEGG: hso:HS_0732 conserved hypothetical protein
YP_001784524.1	SMART: helicase c2; KEGG: hso:HS_0733 ATP-dependent DNA helicase
YP_001784525.1	PFAM: peptidase M22 glycoprotease; KEGG: hso:HS_0734  glycoprotease family protein
YP_001784526.1	Activates fatty acids by binding to coenzyme A
YP_001784527.1	TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: hso:HS_0736 ribonuclease D
YP_001784528.1	PFAM: transport-associated; SMART: transport-associated and nodulation region; KEGG: hso:HS_0737  hemolysin
YP_001784529.1	KEGG: hso:HS_0738 conserved hypothetical protein
YP_001784530.1	PFAM: protein of unknown function UPF0102; KEGG: hso:HS_0739 conserved hypothetical protein
YP_001784531.1	PFAM: LppC family lipoprotein; KEGG: hso:HS_0740 LppC precursor
YP_001784532.1	PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: hso:HS_0741 conserved hypothetical protein
YP_001784533.1	TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: hso:HS_0742 conserved hypothetical protein
YP_001784534.1	PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: hso:HS_0743 ribosomal large subunit pseudouridine synthase B
YP_001784535.1	KEGG: hso:HS_1709 transposase
YP_001784536.1	PFAM: Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0602  adhesin
YP_001784537.1	PFAM: outer membrane efflux protein; KEGG: hso:HS_0746  outer membrane protein
YP_001784538.1	PFAM: regulatory protein DeoR; regulatory protein DeoR; KEGG: hso:HS_0747 deoxyribose operon repressor
YP_001784539.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate
YP_001784540.1	TIGRFAM: ribokinase; PFAM: PfkB domain protein; KEGG: hso:HS_0749 ribokinase
YP_001784541.1	TIGRFAM: L-fucose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_0750 fucose permease
YP_001784542.1	KEGG: hso:HS_0751 hypothetical protein
YP_001784543.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_001784544.1	forms a direct contact with the tRNA during translation
YP_001784545.1	PFAM: glutathione S-transferase domain; KEGG: hso:HS_0754 stringent starvation protein A
YP_001784546.1	PFAM: stringent starvation protein B; KEGG: hso:HS_0755 stringent starvation protein B
YP_001784547.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001784548.1	KEGG: hso:HS_0757 NagC-like transcriptional regulator
YP_001784549.1	PFAM: regulatory protein IclR; IclR family transcripitonal regulator; KEGG: hso:HS_0758 transcriptional regulator, IclR family
YP_001784550.1	NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate
YP_001784551.1	PFAM: tripartite ATP-independent periplasmic transporter DctQ component; KEGG: hso:HS_0760  tripartite ATP-independent periplasmic transporters, DctQ component
YP_001784552.1	TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: citrate transporter; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_0761 integral membrane protein, DedA family
YP_001784553.1	TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_0762  C4-dicarboxylate transporter, periplasmic component
YP_001784554.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0763 ribose ABC transporter ATP-binding protein
YP_001784555.1	PFAM: inner-membrane translocator; KEGG: hso:HS_0764 ribose ABC transporter permease
YP_001784556.1	KEGG: hso:HS_0765 sugar ABC transporter periplasmic protein
YP_001784557.1	PFAM: SMP-30/gluconolaconase/LRE domain protein; KEGG: hso:HS_0766 conserved hypothetical protein
YP_001784558.1	PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_0767 sugar ABC transporter periplasmic sugar-binding protein
YP_001784559.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0768 ribose ABC transporter ATP-binding protein
YP_001784560.1	PFAM: inner-membrane translocator; KEGG: hso:HS_0769 ribose transporter permease
YP_001784561.1	PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_0770 L-xylulose kinase
YP_001784562.1	catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization
YP_001784563.1	L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate
YP_001784564.1	catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
YP_001784565.1	TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: hso:HS_0774  hydrolase, HAD superfamily
YP_001784566.1	PFAM: alpha/beta hydrolase; KEGG: hso:HS_0775 lysophospholipase L2
YP_001784567.1	TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; KEGG: hso:HS_0776 CrcB protein
YP_001784568.1	TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: hso:HS_0777 hydrolase, haloacid dehalogenase-like family
YP_001784569.1	PFAM: nitroreductase; KEGG: hso:HS_0778 NAD(P)H nitroreductase
YP_001784570.1	PFAM: conserved hypothetical protein 743; KEGG: hso:HS_0779 hypothetical protein
YP_001784571.1	TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; KEGG: hso:HS_0780 tyrosine-specific transporter
YP_001784572.1	PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: hso:HS_0781 iron(III) ABC transporter ATP-binding protein
YP_001784573.1	PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0782 iron-uptake permease inner membrane protein
YP_001784574.1	PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_0783 periplasmic iron-binding protein
YP_001784575.1	component of the membrane-bound D-lactate oxidase FAD-binding, NADH independent
YP_001784576.1	TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; PFAM: transferase hexapeptide repeat containing protein; KEGG: hso:HS_0785 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
YP_001784577.1	produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine
YP_001784578.1	PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: hso:HS_0787 DNA-binding protein H-NS
YP_001784579.1	PFAM: Na? antiporter NhaC; KEGG: hso:HS_0788 Na(+)/H(+) antiporter
YP_001784580.1	TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: hso:HS_0789 UDP-glucose-4-epimerase
YP_001784581.1	PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790  large adhesin
YP_001784582.1	PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: hso:HS_0791 oligopeptidase A
YP_001784583.1	PFAM: aminotransferase class I and II; KEGG: hso:HS_0792  aminotransferase
YP_001784584.1	TIGRFAM: Na+/H+ antiporter NhaC; PFAM: Na? antiporter NhaC; KEGG: hso:HS_0793 Na(+)/H(+) antiporter
YP_001784585.1	PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: hso:HS_0794 xylose operon regulatory protein
YP_001784586.1	PFAM: protein of unknown function DUF454; KEGG: hso:HS_0795 hypothetical protein
YP_001784587.1	PFAM: extracellular solute-binding protein family 5; KEGG: hso:HS_0796 oligopeptide transporter periplasmic-binding protein
YP_001784588.1	PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: hso:HS_1548 outer membrane protein P1
YP_001784589.1	KEGG: hso:HS_1709 transposase
YP_001784590.1	PFAM: dihydroorotate dehydrogenase; KEGG: hso:HS_0799 hypothetical protein
YP_001784591.1	TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: hso:HS_0800 tryptophan permease, tryptophan/tyrosine permease family
YP_001784592.1	tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan
YP_001784593.1	catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate
YP_001784594.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
YP_001784595.1	PFAM: protein of unknown function DUF412; KEGG: hso:HS_0804 hypothetical protein
YP_001784596.1	PFAM: protein of unknown function DUF709; KEGG: hso:HS_0805 hypothetical protein
YP_001784597.1	TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: hso:HS_0806 trimethylamine-N-oxide reductase 2, biotin sulfoxide reductase
YP_001784598.1	PFAM: NapC/NirT cytochrome C domain protein; KEGG: hso:HS_0807 cytochrome C protein
YP_001784599.1	KEGG: hso:HS_0808  SAM-dependent methyltransferase
YP_001784600.1	PFAM: beta-lactamase; KEGG: hso:HS_0809 hydroxyacylglutathione hydrolase
YP_001784601.1	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins
YP_001784602.1	NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones
YP_001784603.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
YP_001784604.1	PFAM: ATPase AAA; SMART: AAA ATPase; KEGG: hso:HS_0813 conserved hypothetical protein
YP_001784605.1	participates with LolB in the incorporation of lipoprotein into the outer membrane
YP_001784606.1	PFAM: protein of unknown function DUF1043; KEGG: hso:HS_0815 hypothetical protein
YP_001784607.1	TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: hso:HS_0816 periplasmic serine protease
YP_001784608.1	PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: hso:HS_0817  low molecular weight protein-tyrosine-phosphatase
YP_001784609.1	KEGG: hso:HS_0818 hypothetical protein
YP_001784610.1	in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins
YP_001784611.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_001784612.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_001784613.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_001784614.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
YP_001784615.1	catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
YP_001784616.1	TIGRFAM: penicillin-binding protein 1B; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: hso:HS_0825 penicillin-binding protein 1B
YP_001784617.1	PFAM: uncharacterised conserved protein UCP006287; KEGG: hso:HS_0826 hypothetical protein
YP_001784618.1	TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: hso:HS_0827 HesB family protein
YP_001784619.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn
YP_001784620.1	KEGG: hso:HS_0829 uridylyltransferase; TIGRFAM: protein-P-II uridylyltransferase; PFAM: amino acid-binding ACT domain protein; DNA polymerase beta domain protein region; metal-dependent phosphohydrolase HD sub domain; GlnD PII-uridylyltransferase; SMART: metal-dependent phosphohydrolase HD region
YP_001784621.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; subunit beta of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_001784622.1	Regulates rRNA biosynthesis by transcriptional antitermination
YP_001784623.1	TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein domain protein; KEGG: hso:HS_0832 thiamine-monophosphate kinase
YP_001784624.1	PFAM: phosphatidylglycerophosphatase A; KEGG: hso:HS_0833 phosphatidylglycerophosphatase A
YP_001784625.1	PFAM: lysine exporter (LYSE/YGGA); KEGG: hso:HS_0834  lysine exporter protein
YP_001784626.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
YP_001784627.1	removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction
YP_001784628.1	PFAM: protein of unknown function DUF1260; KEGG: hso:HS_0837 hypothetical protein
YP_001784629.1	catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate
YP_001784630.1	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
YP_001784631.1	PFAM: carbonic anhydrase; KEGG: hso:HS_0840 carbonic anhydrase
YP_001784632.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
YP_001784633.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
YP_001784634.1	monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate
YP_001784635.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_001784636.1	TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity
YP_001784637.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
YP_001784638.1	SohB; periplasmic protein; member of the peptidase S49 family
YP_001784639.1	PFAM: OmpA/MotB domain protein; SmpA/OmlA domain protein; KEGG: hso:HS_0842 outer membrane protein
YP_001784640.1	PFAM: aminoglycoside phosphotransferase; fructosamine kinase; KEGG: hso:HS_0843  fructosamine kinase family enzyme
YP_001784641.1	catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001784642.1	PFAM: thioredoxin domain; KEGG: hso:HS_0845 conserved hypothetical protein
YP_001784643.1	PFAM: xanthine/uracil/vitamin C permease; KEGG: hso:HS_0846 permease, xanthine/uracil family
YP_001784644.1	PFAM: protein of unknown function DUF462; KEGG: hso:HS_0847 hypothetical protein
YP_001784645.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0848 ABC-type multidrug transporter, ATP-binding protein
YP_001784646.1	PFAM: ABC transporter; KEGG: hso:HS_0849 ABC-type multidrug transporter, permease
YP_001784647.1	PFAM: conserved hypothetical protein 730; KEGG: hso:HS_0850 conserved hypothetical protein
YP_001784648.1	catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis
YP_001784649.1	KEGG: hso:HS_0852 hypothetical protein
YP_001784650.1	PFAM: protein of unknown function DUF446; KEGG: hso:HS_0853 hypothetical protein
YP_001784651.1	catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp
YP_001784652.1	PFAM: protein of unknown function UPF0181; KEGG: hso:HS_0855 hypothetical protein
YP_001784653.1	TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: hso:HS_0856 cold shock-like protein
YP_001784654.1	PFAM: protein of unknown function DUF1047; KEGG: hso:HS_0857 hypothetical protein
YP_001784655.1	KEGG: hso:HS_0858 ATP-dependent Lon protease
YP_001784656.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_001784657.1	KEGG: hso:HS_0860 hypothetical protein
YP_001784658.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_001784659.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
YP_001784660.1	TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs
YP_001784661.1	acts with MukB and MukE to condense the chromosome and allow for segregation during cell division
YP_001784662.1	acts with MukB and MukF to condense the chromosome and allow for segregation during cell division
YP_001784663.1	SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects
YP_001784664.1	PFAM: protein of unknown function DUF6 transmembrane; KEGG: hso:HS_0867  permease
YP_001784665.1	KEGG: hso:HS_0868 hypothetical protein
YP_001784666.1	KEGG: hso:HS_0870 hypothetical protein
YP_001784667.1	KEGG: hso:HS_0871 hypothetical protein
YP_001784668.1	KEGG: hso:HS_0871 hypothetical protein
YP_001784669.1	KEGG: sfr:Sfri_1956 type I site-specific deoxyribonuclease, HsdR family protein
YP_001784670.1	Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
YP_001784671.1	KEGG: bfs:BF2816 hypothetical protein
YP_001784672.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
YP_001784673.1	PFAM: SNARE associated Golgi protein; KEGG: hso:HS_0874 hypothetical protein
YP_001784674.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_001784675.1	PFAM: ribosomal protein L35; KEGG: hso:HS_0876 50S ribosomal protein L35
YP_001784676.1	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
YP_001784677.1	Global transcription factor that controls the expression of over 100 target genes in response to anoxia
YP_001784678.1	with UspC and UspD is involved in resistance to UV irradiation
YP_001784679.1	TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; KEGG: hso:HS_0880 folylpolyglutamate synthase
YP_001784680.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits
YP_001784681.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
YP_001784682.1	PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: hso:HS_0883  TrpH protein
YP_001784683.1	TIGRFAM: aminopeptidase N; PFAM: peptidase M1 membrane alanine aminopeptidase; KEGG: hso:HS_0884 aminopeptidase N
YP_001784684.1	TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; KEGG: hso:HS_0885 glycogen phosphorylase
YP_001784685.1	catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose
YP_001784686.1	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate
YP_001784687.1	TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: hso:HS_0888 glycogen operon protein
YP_001784688.1	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain
YP_001784689.1	TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77; KEGG: hso:HS_0890 4-alpha-glucanotransferase
YP_001784690.1	PFAM: protein of unknown function UPF0153; KEGG: hso:HS_0891 hypothetical protein
YP_001784691.1	PFAM: peptidase M16 domain protein; KEGG: hso:HS_0892 zinc protease
YP_001784692.1	PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0894 hypothetical protein
YP_001784693.1	catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001784694.1	PFAM: protein of unknown function UPF0052 and CofD; KEGG: hso:HS_0896 hypothetical protein
YP_001784695.1	PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: hso:HS_0897 tetrathionate reductase, subunit A
YP_001784696.1	PFAM: polysulphide reductase NrfD; KEGG: hso:HS_0898 tetrathionate reductase, subunit C
YP_001784697.1	PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: hso:HS_0899 tetrathionate reductase, subunit B
YP_001784698.1	PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: hso:HS_0900 sensor kinase
YP_001784699.1	PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: hso:HS_0901 two component response regulator
YP_001784700.1	Required for the synthesis of the thiazole moiety
YP_001784701.1	TIGRFAM: exodeoxyribonuclease VII small subunit; PFAM: exonuclease VII small subunit; KEGG: hso:HS_0903 exodeoxyribonuclease VII small subunit
YP_001784702.1	PFAM: polyprenyl synthetase; KEGG: hso:HS_0904 farnesyl-diphosphate synthase
YP_001784703.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
YP_001784704.1	PFAM: protein of unknown function DUF340 membrane; KEGG: hso:HS_0906  permease
YP_001784705.1	catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP
YP_001784706.1	TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: hso:HS_0908 protease IV family
YP_001784707.1	PFAM: nitroreductase; KEGG: hso:HS_0909  nitroreductase family protein
YP_001784708.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
YP_001784709.1	TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: hso:HS_0911 molybdopterin biosynthesis protein
YP_001784710.1	ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase
YP_001784711.1	TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase; KEGG: hso:HS_0913 phosphoribosylglycinamide formyltransferase
YP_001784712.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
YP_001784713.1	catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate
YP_001784714.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
YP_001784715.1	PFAM: colicin V production protein; KEGG: hso:HS_0917 colicin V production protein
YP_001784716.1	TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: hso:HS_0918 polysialic acid capsule expression protein, KpsF/GutQ family protein
YP_001784717.1	TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: hso:HS_0919 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase
YP_001784718.1	PFAM: ferritin; KEGG: hso:HS_0920 ferritin like protein 1
YP_001784719.1	PFAM: ferritin; KEGG: hso:HS_0921 ferritin like protein 2
YP_001784720.1	PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: hso:HS_0922 transcriptional regulator, DeoR family
YP_001784721.1	KEGG: hso:HS_0923 hypothetical protein
YP_001784722.1	transports degraded pectin products into the bacterial cell
YP_001784723.1	catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate)
YP_001784724.1	catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde
YP_001784725.1	PFAM: pyridoxal-dependent decarboxylase; KEGG: hso:HS_0927 L-2,4-diaminobutyrate decarboxylase
YP_001784726.1	TIGRFAM: exodeoxyribonuclease V, subunit alpha; KEGG: hso:HS_0928 exodeoxyribonuclease V, alpha chain
YP_001784727.1	TIGRFAM: exodeoxyribonuclease V subunit beta; PFAM: UvrD/REP helicase; KEGG: hso:HS_0929 exodeoxyribonuclease V, beta chain
YP_001784728.1	metalloprotease
YP_001784729.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
YP_001784730.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
YP_001784731.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal
YP_001784732.1	TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; protein of unkown function DUF1946 PP-loop ATpase; KEGG: hso:HS_0934 cell-cycle protein
YP_001784733.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_001784734.1	converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer
YP_001784735.1	unwinds double stranded DNA
YP_001784736.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive
YP_001784737.1	part of the ATP-dependent transporter LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane
YP_001784738.1	TIGRFAM: lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0943 lipoprotein releasing system, ATP-binding protein
YP_001784739.1	TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: hso:HS_0944 lipoprotein releasing system, transmembrane protein
YP_001784740.1	Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor
YP_001784741.1	catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis
YP_001784742.1	KEGG: hso:HS_0947 hypothetical protein
YP_001784743.1	TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: hso:HS_0948 peptide release factor glutamine N(5)-methylase
YP_001784744.1	PFAM: RDD domain containing protein; KEGG: hso:HS_0949 hypothetical protein
YP_001784745.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_001784746.1	PFAM: Lipooligosaccharide sialyltransferase; KEGG: hdu:HD0686 lipooligosaccharide sialyltransferase
YP_001784747.1	PFAM: 17 kDa surface antigen; KEGG: hso:HS_0952 outer membrane lipoprotein pcp precursor
YP_001784748.1	KEGG: hso:HS_0953 hypothetical protein
YP_001784749.1	PFAM: protein of unknown function DUF991; KEGG: hso:HS_0954 hypothetical protein
YP_001784750.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_001784751.1	TIGRFAM: succinyl-CoA synthetase, subunit alpha; PFAM: CoA-binding protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: hso:HS_0956 succinyl-CoA synthetase, subunit alpha
YP_001784752.1	catalyzes the interconversion of succinyl-CoA and succinate
YP_001784753.1	TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: hso:HS_0958 dihydrolipoamide succinyltransferase
YP_001784754.1	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide
YP_001784755.1	TIGRFAM: citrate synthase I; PFAM: citrate synthase; KEGG: hso:HS_0960 citrate synthase
YP_001784756.1	B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA
YP_001784757.1	PFAM: ferredoxin; KEGG: hso:HS_0962  ferredoxin 2Fe-2S type
YP_001784758.1	exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH
YP_001784759.1	dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate
YP_001784760.1	PFAM: nuclease (SNase domain protein); KEGG: hso:HS_0966  nuclease
YP_001784761.1	PFAM: aminotransferase class V; KEGG: hso:HS_0967 cysteine desulfurase, aminotransferase, class V
YP_001784762.1	PFAM: Fe-S metabolism associated SufE; KEGG: hso:HS_0968 conserved hypothetical protein
YP_001784764.1	PFAM: filamentation induced by cAMP protein Fic; KEGG: xft:PD1006 cell filamentation protein
YP_001784765.1	TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; KEGG: hso:HS_0969  RelB protein
YP_001784766.1	TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: hso:HS_0970 hypothetical protein
YP_001784767.1	PFAM: porin Gram-negative type; KEGG: hso:HS_0971 outer membrane protein, OmpH family
YP_001784768.1	PFAM: virulence-associated protein D (VapD) conserved region; KEGG: rpc:RPC_2389 virulence-associated protein D
YP_001784769.1	PFAM: protein of unknown function DUF1778; KEGG: hin:HI0420 hypothetical protein
YP_001784770.1	PFAM: GCN5-related N-acetyltransferase; KEGG: hso:HS_1675  histone acetyltransferase
YP_001784771.1	PFAM: hypothetical protein; KEGG: hso:HS_0973 hypothetical protein
YP_001784772.1	PFAM: protein of unknown function DUF1049; KEGG: hso:HS_0974 hypothetical protein
YP_001784773.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
YP_001784774.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
YP_001784775.1	TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: hso:HS_0977 cytidylate kinase 1
YP_001784776.1	adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis
YP_001784777.1	PFAM: outer membrane chaperone Skp (OmpH); KEGG: hso:HS_0979 outer membrane protein
YP_001784778.1	PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: hso:HS_0980 surface antigen
YP_001784779.1	TIGRFAM:  membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: hso:HS_0981  zinc metalloprotease
YP_001784780.1	PFAM: phosphatidate cytidylyltransferase; KEGG: hso:HS_0982 phosphatidate cytidylyltransferase
YP_001784781.1	TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; KEGG: hso:HS_0983 undecaprenyl pyrophosphate synthase
YP_001784782.1	KEGG: hso:HS_0984 hypothetical protein
YP_001784783.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
YP_001784784.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_001784785.1	Catalyzes the phosphorylation of UMP to UDP
YP_001784786.1	KEGG: hso:HS_0988 hypothetical protein
YP_001784787.1	KEGG: hso:HS_0989 hypothetical protein
YP_001784788.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_001784789.1	TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: hso:HS_0991 7,8-dihydro-8-oxoguanine-triphosphatase
YP_001784790.1	involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain
YP_001784791.1	PFAM: protein of unknown function DUF441; KEGG: hso:HS_0993  permease
YP_001784792.1	catalyzes the formation of oxaloacetate from phosphoenolpyruvate
YP_001784793.1	highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein
YP_001784794.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
YP_001784795.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
YP_001784796.1	Incorporates lipoproteins in the outer membrane after they are released by the LolA protein
YP_001784797.1	KEGG: hso:HS_0999 hypothetical protein
YP_001784798.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_001784799.1	PFAM: protein of unknown function UPF0044; KEGG: hso:HS_1001 conserved hypothetical protein
YP_001784800.1	TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: hso:HS_1002 arsenate reductase
YP_001784801.1	PFAM: protein of unknown function UPF0118; KEGG: hso:HS_1003 permease
YP_001784802.1	YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function
YP_001784803.1	KEGG: hit:NTHI0339 hypothetical protein
YP_001784804.1	PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1085  large adhesin
YP_001784805.1	KEGG: hso:HS_1010 biotin synthetase; TIGRFAM: biotin synthase; PFAM: radical SAM protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB
YP_001784806.1	TIGRFAM: ABC transporter ATPase, ThiQ subfamily; PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1011 thiamine ABC transporter ATP-binding protein
YP_001784807.1	permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine
YP_001784808.1	TIGRFAM: ABC transporter periplasmic binding protein, thiB subfamily; thiamine ABC transporter periplasmic binding protein; KEGG: hso:HS_1013 thiamine ABC transporter periplasmic-binding protein
YP_001784809.1	TIGRFAM: cysteine protease domain, YopT-type; filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: filamentation induced by cAMP protein Fic; peptidase C58 Yersinia/Haemophilus virulence surface antigen; Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: pmu:PM0059  virulence factor, filamentous hemaglutinin
YP_001784810.1	PFAM: Hemolysin activator HlyB domain protein; polypeptide-transport-associated domain protein ShlB-type; KEGG: pmu:PM0056 hemolysin accessory protein
YP_001784811.1	PFAM: citrate transporter; Na? antiporter NhaC; KEGG: hso:HS_1014 conserved hypothetical protein
YP_001784812.1	KEGG: hso:HS_1015 hypothetical protein
YP_001784813.1	KEGG: hso:HS_1015a hypothetical protein
YP_001784814.1	Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
YP_001784815.1	in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ
YP_001784816.1	in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme
YP_001784817.1	KEGG: hso:HS_1019  permease
YP_001784818.1	catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA
YP_001784819.1	involved in the transport of lipid A across the inner membrane
YP_001784820.1	TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase; ComEC/Rec2-related protein; KEGG: hso:HS_1022 recombination protein 2
YP_001784821.1	TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: hso:HS_1023 DnaK suppressor protein
YP_001784822.1	TIGRFAM: poly(A) polymerase; PFAM: polynucleotide adenylyltransferase region; KEGG: hso:HS_1024 poly(A) polymerase
YP_001784823.1	TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: hso:HS_1025 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YP_001784824.1	catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate
YP_001784825.1	catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate
YP_001784826.1	PFAM: molybdopterin biosynthesis MoaE protein; KEGG: hso:HS_1028 molybdopterin biosynthesis protein, E chain
YP_001784827.1	catalyzes the conversion of molybdopterin precursor Z into molybdopterin
YP_001784828.1	TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; KEGG: hso:HS_1030 molybdenum cofactor biosynthesis protein, C chain
YP_001784829.1	together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z
YP_001784830.1	binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers
YP_001784831.1	LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation
YP_001784832.1	TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: hso:HS_1034  glutaredoxin-like protein
YP_001784833.1	PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: hso:HS_1035 hemagglutinin antigen
YP_001784834.1	PFAM: peptidase M23B; KEGG: hso:HS_1036  metalloprotease
YP_001784835.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1037 high-affinity zinc uptake system, ATP-binding protein
YP_001784836.1	PFAM: ABC transporter; KEGG: hso:HS_1038 high-affinity zinc uptake system, membrane protein
YP_001784837.1	TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: hso:HS_1039 amino acid carrier protein
YP_001784838.1	catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine
YP_001784839.1	PFAM: phosphoesterase PA-phosphatase related; KEGG: hso:HS_1042 phosphatidylglycerophosphatase B
YP_001784840.1	catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate
YP_001784841.1	KEGG: hdu:HD1689  transposase
YP_001784843.1	KEGG: dde:Dde_1416 hypothetical protein
YP_001784845.1	KEGG: plu:plu0643 hypothetical protein
YP_001784846.1	KEGG: plu:plu0643 hypothetical protein
YP_001784847.1	KEGG: hdu:HD1698 hypothetical protein
YP_001784848.1	PFAM: FAD linked oxidase; KEGG: hso:HS_1044 conserved hypothetical protein
YP_001784849.1	PFAM: thioesterase superfamily protein; KEGG: hso:HS_1045 hypothetical protein
YP_001784850.1	KEGG: hso:HS_1046  permease
YP_001784851.1	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
YP_001784852.1	PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_1048 spermidine/putrescine-binding periplasmic protein
YP_001784853.1	TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: hso:HS_1049 protease DegS precursor
YP_001784854.1	TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: hso:HS_1050 riboflavin biosynthesis protein
YP_001784855.1	PFAM: ATP-cone domain protein; KEGG: hso:HS_1051 conserved hypothetical protein
YP_001784856.1	PFAM: branched-chain amino acid ABC transporter; KEGG: hso:HS_1052  branched-chain amino acid ABC transporterer
YP_001784857.1	PFAM: AzlC family protein; KEGG: hso:HS_1053  branched-chain amino acid ABC transporterer
YP_001784858.1	PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: hso:HS_1054 transcriptional regulator
YP_001784859.1	oxidizes malate to oxaloacetate
YP_001784860.1	regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes
YP_001784861.1	PFAM: NAD-dependent epimerase/dehydratase; domain of unknown function DUF1731; KEGG: hso:HS_1057 conserved hypothetical protein
YP_001784862.1	PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790  large adhesin
YP_001784863.1	TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: hso:HS_1059 electron transport complex protein
YP_001784864.1	part of membrane-bound complex thought to be involved in electron transport to nitrogen
YP_001784865.1	part of membrane-bound complex thought to be involved in electron transport to nitrogen
YP_001784866.1	RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents
YP_001784867.1	part of membrane-bound complex hought to be involved in electron transport to nitrogen
YP_001784868.1	in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase
YP_001784869.1	KEGG: hso:HS_1065 endonuclease III; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop
YP_001784870.1	PFAM: sodium:neurotransmitter symporter; KEGG: hso:HS_1066  sodium-dependent transporter
YP_001784872.1	KEGG: hso:HS_1067 hypothetical protein
YP_001784873.1	PFAM: hypothetical protein; KEGG: hso:HS_1068 hypothetical protein
YP_001784874.1	TIGRFAM: integral membrane protein, PqiA family; PFAM: paraquat-inducible protein A; KEGG: hso:HS_1069 hypothetical protein
YP_001784875.1	affects solute and DNA transport through an unknown mechanism
YP_001784876.1	Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3
YP_001784877.1	KEGG: hso:HS_1072 hypothetical protein
YP_001784878.1	PFAM: protein of unknown function DUF882; peptidase M15A; KEGG: hso:HS_1073 hypothetical protein
YP_001784879.1	PFAM: beta-lactamase; KEGG: hso:HS_1074  glyoxalase II family protein
YP_001784880.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_001784881.1	Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine
YP_001784882.1	PFAM: protein of unknown function DUF218; KEGG: hso:HS_1077 SanA protein
YP_001784883.1	TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: hso:HS_1078  sodium/calcium exchange protein
YP_001784884.1	PFAM: high-affinity nickel-transporter; KEGG: hso:HS_1079  permease
YP_001784885.1	PFAM: protein of unknown function DUF1007; KEGG: hso:HS_1080 hypothetical protein
YP_001784886.1	PFAM: protein of unknown function UPF0079; KEGG: hso:HS_1081  ATPase
YP_001784887.1	PFAM: peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: hso:HS_1082 N-acetylmuramoyl-L-alanine amidase
YP_001784888.1	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YP_001784889.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_001784890.1	KEGG: mmu:673901 hypothetical protein LOC673901
YP_001784891.1	PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790  large adhesin
YP_001784892.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
YP_001784893.1	TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: hso:HS_1156 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase
YP_001784894.1	functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase
YP_001784895.1	can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component
YP_001784896.1	can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component
YP_001784897.1	PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_1160 spermidine/putrescine-binding periplasmic protein
YP_001784898.1	TIGRFAM: transcription-repair coupling factor; PFAM: helicase; transcription factor CarD; TRCF domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: hso:HS_1161 transcription-repair coupling factor
YP_001784899.1	Involved in ubiquinone biosynthesis
YP_001784900.1	negatively supercoils closed circular double-stranded DNA
YP_001784901.1	KEGG: hso:HS_1164 hypothetical protein
YP_001784902.1	TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: hso:HS_1165 alkylphosphonate uptake protein
YP_001784903.1	TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: hso:HS_1166 tyrosine-specific transporter
YP_001784904.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_001784905.1	PFAM: BolA family protein; KEGG: hso:HS_1168  BolA-like protein
YP_001784906.1	KEGG: hso:HS_1169 conserved hypothetical protein
YP_001784907.1	PFAM: toluene tolerance family protein; KEGG: hso:HS_1170 conserved hypothetical protein
YP_001784908.1	PFAM: hypothetical protein; KEGG: hso:HS_1171 hypothetical protein
YP_001784909.1	PFAM: protein of unknown function DUF140; KEGG: hso:HS_1172 permease,  ABC transporter
YP_001784910.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1173 ABC transporter ATP-binding protein
YP_001784911.1	PFAM: protein of unknown function DUF1239; KEGG: hso:HS_1174 hypothetical protein
YP_001784912.1	TIGRFAM: cell envelope biogenesis YhbN; PFAM: OstA family protein; KEGG: hso:HS_1175 hypothetical protein
YP_001784913.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1176 ABC transporter ATP-binding protein
YP_001784914.1	PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: hso:HS_1177 nitrogen regulatory IIA protein
YP_001784915.1	PFAM: uncharacterised P-loop ATPase protein UPF0042; KEGG: hso:HS_1178 hypothetical protein
YP_001784916.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
YP_001784917.1	KEGG: hso:HS_1180 ATP-binding protein, MRP protein
YP_001784918.1	TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: hit:NTHI0839 hypothetical protein
YP_001784919.1	TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; KEGG: hit:NTHI0838 DNA-damage-inducible protein J, negative regulator of translation
YP_001784920.1	KEGG: hso:HS_0574  oxidoreductase component
YP_001784921.1	PFAM: NAD(P)H dehydrogenase (quinone); KEGG: hso:HS_0573 NAD(P)H2 dehydrogenase, quinone family
YP_001784922.1	PFAM: protein of unknown function DUF107; KEGG: hso:HS_0572  regulator of membrane protease activity
YP_001784923.1	PFAM: hypothetical protein; KEGG: hso:HS_0571  membrane protease band 7 family
YP_001784924.1	catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis
YP_001784925.1	TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: hso:HS_0569 acetyl-CoA carboxylase
YP_001784926.1	an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_001784927.1	mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase
YP_001784928.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
YP_001784929.1	TIGRFAM:  hypothetical protein; PFAM: dihydrouridine synthase; dihydroorotate dehydrogenase; KEGG: hso:HS_0565 tRNA-dihydrouridine synthase B
YP_001784930.1	Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription
YP_001784931.1	catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate
YP_001784932.1	catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA
YP_001784933.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_001784934.1	KEGG: hso:HS_0560 type I restriction enzyme, specificity subunit
YP_001784935.1	TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases; KEGG: hso:HS_0559 type I site-specific deoxyribonuclease, restriction subunit
YP_001784936.1	PFAM: Abi family protein; KEGG: noc:Noc_1806 abortive infection bacteriophage resistance protein
YP_001784937.1	PFAM: restriction modification system DNA specificity domain; KEGG: hso:HS_0556  type I restriction enzyme, specificity subunit
YP_001784938.1	PFAM: filamentation induced by cAMP protein Fic; KEGG: hin:HI0977 cell filamentation protein
YP_001784939.1	TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: llc:LACR_1215 type I restriction-modification system methyltransferase subunit
YP_001784940.1	KEGG: mfa:Mfla_1216 restriction modification system DNA specificity domain
YP_001784941.1	PFAM: phage integrase family protein; KEGG: hso:HS_0555 phage integrase
YP_001784942.1	KEGG: yps:YPTB0536  type I restriction enzyme, S subunit
YP_001784944.1	PFAM: acyltransferase 3; KEGG: hso:HS_0553  acetyltransferase
YP_001784945.1	PFAM: transposase IS200-family protein; KEGG: hso:HS_1391 transposase
YP_001784946.1	TIGRFAM: transposase, IS605 OrfB family; PFAM:  transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: hso:HS_0583 transposase
YP_001784947.1	KEGG: hso:HS_0525 hypothetical protein
YP_001784948.1	KEGG: hso:HS_0527 hypothetical protein
YP_001784949.1	KEGG: hso:HS_0528 hypothetical protein
YP_001784951.1	TIGRFAM: transposase, IS605 OrfB family; PFAM:  transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: hso:HS_0583 transposase
YP_001784952.1	PFAM: transposase IS200-family protein; KEGG: hso:HS_1391 transposase
YP_001784954.1	KEGG: plu:plu0225 hypothetical protein
YP_001784955.1	KEGG: ngo:NGO1591 hypothetical protein
YP_001784956.1	KEGG: nme:NMB0372 hypothetical protein
YP_001784958.1	KEGG: msu:MS1164 hypothetical protein
YP_001784960.1	KEGG: plu:plu1354 hypothetical protein
YP_001784961.1	KEGG: msu:MS1167 FhaB protein
YP_001784963.1	KEGG: bld:BLi01315 YeeF
YP_001784966.1	PFAM: Cytotoxic domain protein; KEGG: cvi:CV2871 probable hemagglutinin
YP_001784967.1	KEGG: msu:MS1163 FhaB protein
YP_001784971.1	TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: msu:MS1167 FhaB protein
YP_001784972.1	KEGG: msu:MS1169 FhaC protein
YP_001784974.1	TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: hso:HS_0541 conserved hypothetical protein
YP_001784975.1	TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; methyltransferase type 11; methyltransferase type 12; KEGG: hso:HS_0542 ubiquinone/menaquinone biosynthesis methyltransferase
YP_001784976.1	PFAM: protein of unknown function DUF1243; KEGG: hso:HS_0543 conserved hypothetical protein
YP_001784977.1	TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: hso:HS_0544 ubiquinone biosynthesis protein
YP_001784978.1	TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: hso:HS_0545 sec-independent protein translocase protein, TatA/E family
YP_001784979.1	TIGRFAM: twin-arginine translocation protein, TatB subunit; KEGG: hso:HS_0546 sec-independent protein translocase protein
YP_001784980.1	TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: hso:HS_0547 sec-independent protein translocase protein
YP_001784981.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
YP_001784982.1	non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis
YP_001784983.1	catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
YP_001784984.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_001784985.1	KEGG: net:Neut_2561 type III restriction enzyme, res subunit
YP_001784986.1	PFAM: helicase; type III restriction protein res subunit; SMART: DEAD-like helicases; KEGG: net:Neut_2561 type III restriction enzyme, res subunit
YP_001784987.1	KEGG: hso:HS_0638 Lob1 protein
YP_001784988.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_001784989.1	KEGG: hso:HS_0553  acetyltransferase
YP_001784990.1	TIGRFAM: transposase, IS605 OrfB family; PFAM:  transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: hso:HS_0583 transposase
YP_001784991.1	PFAM: transposase IS200-family protein; KEGG: hso:HS_1391 transposase
YP_001784992.1	KEGG: hso:HS_0524 hypothetical protein
YP_001784993.1	KEGG: hso:HS_0523 hypothetical protein
YP_001784994.1	PFAM: prophage CP4-57 regulator; KEGG: hso:HS_0522  phage transcriptional regulator
YP_001784996.1	PFAM: phage integrase family protein; KEGG: hso:HS_0519 phage integrase
YP_001784997.1	KEGG: efa:EF3160 hypothetical protein
YP_001784998.1	KEGG: plu:plu4544 hypothetical protein
YP_001784999.1	PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: hso:HS_0001 integrase
YP_001785000.1	PFAM: Integrase catalytic region; KEGG: ssp:SSP1423 transposase
YP_001785001.1	KEGG: hit:NTHI0153  type I restriction enzyme M subunit
YP_001785002.1	KEGG: hdu:HD0915 hypothetical protein
YP_001785003.1	PFAM: domain of unknown function DUF1738; KEGG: hso:HS_1780  antirestriction protein
YP_001785004.1	KEGG: hso:HS_1781 Haemophilus-specific protein, uncharacterized
YP_001785007.1	KEGG: hso:HS_1778 Haemophilus-specific protein, uncharacterized
YP_001785008.1	KEGG: hit:NTHI0148 hypothetical protein
YP_001785009.1	PFAM: protein of unknown function DUF1525; KEGG: hso:HS_1776 hypothetical protein
YP_001785010.1	PFAM: protein of unknown function DUF1527; KEGG: hso:HS_1775 hypothetical protein
YP_001785011.1	KEGG: hso:HS_1774 hypothetical protein
YP_001785012.1	KEGG: hit:NTHI0144 hypothetical protein
YP_001785013.1	KEGG: spa:M6_Spy0066 unknown phage protein
YP_001785015.1	KEGG: hit:NTHI0137 conserved  membrane protein
YP_001785016.1	KEGG: hso:HS_1766 Haemophilus-specific protein, uncharacterized
YP_001785017.1	KEGG: hdu:HD0931 hypothetical protein
YP_001785018.1	KEGG: hso:HS_1764 hypothetical protein
YP_001785019.1	KEGG: hso:HS_1763 hypothetical protein
YP_001785020.1	KEGG: hdu:HD0935 hypothetical protein
YP_001785021.1	KEGG: hit:NTHI0131 hypothetical protein
YP_001785022.1	KEGG: hso:HS_1760 hypothetical protein
YP_001785023.1	KEGG: hso:HS_1759 hypothetical protein
YP_001785024.1	KEGG: hso:HS_1758 Haemophilus-specific protein, uncharacterized
YP_001785025.1	KEGG: hso:HS_1757 Haemophilus-specific protein, uncharacterized
YP_001785026.1	KEGG: hso:HS_1756 hypothetical protein
YP_001785027.1	KEGG: hso:HS_1789 Haemophilus-specific protein, uncharacterized
YP_001785028.1	KEGG: hit:NTHI0126 conserved  membrane protein
YP_001785029.1	KEGG: hso:HS_1752 Haemophilus-specific protein, uncharacterized
YP_001785030.1	KEGG: hso:HS_1751 hypothetical protein
YP_001785031.1	KEGG: hso:HS_1750 hypothetical protein
YP_001785032.1	KEGG: hit:NTHI0122 conserved  exported protein
YP_001785033.1	KEGG: hso:HS_1747 hypothetical protein
YP_001785034.1	KEGG: hit:NTHI0120 conserved  lipoprotein
YP_001785035.1	KEGG: pau:PA14_59530 hypothetical protein
YP_001785036.1	KEGG: hso:HS_1744 Haemophilus-specific protein, uncharacterized
YP_001785037.1	KEGG: hso:HS_1739 hypothetical protein
YP_001785039.1	KEGG: hso:HS_1738 hypothetical protein
YP_001785040.1	decatenates replicating daughter chromosomes
YP_001785041.1	KEGG: hso:HS_1732 Haemophilus-specific protein, uncharacterized
YP_001785042.1	KEGG: hso:HS_1735 Haemophilus-specific protein, uncharacterized
YP_001785043.1	PFAM: aldo/keto reductase; KEGG: ade:Adeh_3215 aldo/keto reductase
YP_001785045.1	PFAM: protein of unknown function DUF411; KEGG: pmu:PM1939 hypothetical S.typhimurium
YP_001785046.1	PFAM: multicopper oxidase type 1; multicopper oxidase type 2; multicopper oxidase type 3; KEGG: pmu:PM1938 hypothetical E.coli
YP_001785047.1	KEGG: bam:Bamb_5387 alcohol dehydrogenase, zinc-binding domain protein
YP_001785048.1	TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; KEGG: hit:NTHI0403 probable heavy metal dependent transcriptional regulator
YP_001785049.1	PFAM: protein of unknown function DUF411; KEGG: pmu:PM1939 hypothetical S.typhimurium
YP_001785050.1	PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: pmu:PM1938 hypothetical E.coli
YP_001785051.1	TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: haloacid dehalogenase; E1-E2 ATPase-associated domain protein; KEGG: neu:NE1216 haloacid dehalogenase/epoxide hydrolase family:E1-E2 ATPase
YP_001785052.1	PFAM: protein of unknown function DUF305; KEGG: par:Psyc_0285 hypothetical protein
YP_001785053.1	KEGG: ret:RHE_PF00025 hypothetical protein
YP_001785054.1	PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: sty:HCM1.243 tetracycline repressor protein
YP_001785055.1	PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: sty:HCM1.241c tetracycline resistance protein
YP_001785056.1	PFAM: small multidrug resistance protein; KEGG: nme:NMB0393 multidrug resistance protein
YP_001785057.1	PFAM: regulatory protein MarR; KEGG: msu:MS2146 MarR protein
YP_001785058.1	PFAM: protein of unknown function DUF1304; KEGG: nmc:NMC0467 hypothetical protein
YP_001785059.1	KEGG: msu:MS2120 hypothetical protein
YP_001785060.1	PFAM: cation efflux protein; KEGG: pmu:PM1942 unknown
YP_001785061.1	PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; KEGG: pmu:PM1941 transcriptional regulator, merR family
YP_001785062.1	KEGG: pmu:PM1943 hypothetical Synechocystis sp.
YP_001785063.1	KEGG: pmu:PM1943 hypothetical Synechocystis sp.
YP_001785064.1	PFAM: alcohol dehydrogenase zinc-binding domain protein; KEGG: pmu:PM1940 quinone reductase homolog
YP_001785065.1	TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: hso:HS_1729 single-stranded DNA binding protein
YP_001785066.1	KEGG: hit:NTHI0108 hypothetical protein
YP_001785067.1	KEGG: hit:NTHI0107 hypothetical protein
YP_001785068.1	KEGG: hit:NTHI0106 hypothetical protein
YP_001785069.1	KEGG: hdu:HD0969 hypothetical protein
YP_001785070.1	KEGG: hit:NTHI0103 hypothetical protein
YP_001785071.1	TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase; SMART: ATPase AAA; KEGG: hit:NTHI0102 replicative DNA helicase
YP_001785072.1	KEGG: hit:NTHI0101 predicted ATPase involved in chromosome partitioning
YP_001785073.1	PFAM: permease YjgP/YjgQ family protein; KEGG: hso:HS_0518 conserved permease
YP_001785074.1	PFAM: permease YjgP/YjgQ family protein; KEGG: hso:HS_0517 conserved permease
YP_001785075.1	catalyzes the removal of N-terminal amino acids preferably leucine from various peptides
YP_001785076.1	PFAM: regulatory protein GntR HTH; regulatory protein DeoR; hypothetical protein; regulatory protein DeoR; KEGG: hso:HS_0515 glycerol-3-phosphate regulon repressor (glp operon repressor)
YP_001785077.1	anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate
YP_001785078.1	sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters
YP_001785079.1	anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor
YP_001785080.1	TIGRFAM: phosphoglycerate transporter; glycerol-3-phosphate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_0511 glycerol 3-phosphate transporter
YP_001785081.1	hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic
YP_001785082.1	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity
YP_001785083.1	PFAM: protein of unknown function DUF28; KEGG: hso:HS_0508 hypothetical protein
YP_001785084.1	converts dATP to dAMP and pyrophosphate
YP_001785085.1	PFAM: protein of unknown function UPF0125; KEGG: hso:HS_0506 hypothetical protein
YP_001785086.1	PFAM: cyclase/dehydrase; KEGG: hso:HS_0505 hypothetical protein
YP_001785087.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_001785088.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_001785089.1	TIGRFAM: lactoylglutathione lyase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: hso:HS_0502 lactoylglutathione lyase (glyoxalase I)
YP_001785090.1	Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A)
YP_001785091.1	PFAM: multicopper oxidase type 3; KEGG: hso:HS_0500 suppressor of FtsI
YP_001785092.1	TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; KEGG: hso:HS_0499 1-acylglycerol-3-phosphate O-acyltransferase (1-acyl-sn-glycerol-3-phosphate acyltransferase)
YP_001785093.1	catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine
YP_001785094.1	unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.
YP_001785095.1	KEGG: hso:HS_0496 conserved hypothetical protein
YP_001785096.1	glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence
YP_001785097.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_001785098.1	bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine
YP_001785099.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_001785100.1	KEGG: hso:HS_0337 hypothetical protein
YP_001785101.1	alanine acetyltransferase that specifically acetylates ribosomal protein S18
YP_001785102.1	with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB
YP_001785103.1	KEGG: hso:HS_0489 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16; ATPase AAA central domain protein; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA
YP_001785104.1	TIGRFAM: HflC protein; PFAM: hypothetical protein; KEGG: hso:HS_0488 HflC protein
YP_001785105.1	TIGRFAM: HflK protein; PFAM: hypothetical protein; KEGG: hso:HS_0487 HflK protein
YP_001785106.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
YP_001785107.1	TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: hso:HS_0484 cation efflux protein
YP_001785108.1	KEGG: hso:HS_0483 hypothetical protein
YP_001785109.1	PFAM: protein of unknown function DUF328; KEGG: hso:HS_0482 hypothetical protein
YP_001785110.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YP_001785111.1	stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit
YP_001785112.1	glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_001785113.1	PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1058  large adhesin
YP_001785114.1	PFAM: glycosyltransferase family 52; KEGG: pmu:PM0508 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 3-sialyltransfera se
YP_001785115.1	KEGG: hso:HS_1633 conserved hypothetical protein
YP_001785116.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
YP_001785117.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
YP_001785118.1	PFAM: YheO domain protein; KEGG: hso:HS_1636 hypothetical protein
YP_001785119.1	PFAM: peptidylprolyl isomerase FKBP-type; KEGG: hso:HS_1637 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase)
YP_001785120.1	PFAM: SlyX family protein; KEGG: hso:HS_1638  SlyX family protein
YP_001785121.1	PFAM: NUDIX hydrolase; KEGG: hso:HS_1639  NTP pyrophosphohydrolase, MutT/NUDIX family
YP_001785122.1	PFAM: pseudouridine synthase; KEGG: hso:HS_1640 ribosomal large subunit pseudouridine synthase
YP_001785123.1	TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate dehydrogenase NADP-dependent monomeric type; KEGG: hso:HS_1641 isocitrate dehydrogenase
YP_001785124.1	PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; KEGG: hso:HS_1642 hypothetical protein
YP_001785125.1	PFAM:  esterase; KEGG: hso:HS_1643 hypothetical protein
YP_001785126.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_001785127.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_001785128.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_001785129.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_001785130.1	becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers
YP_001785131.1	PFAM: RNA-binding S4 domain protein; KEGG: hso:HS_1649  heat shock protein 15
YP_001785132.1	TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: hso:HS_1650 3'-phosphoadenosine 5'-phosphosulfate (PapS) 3'-phosphatase
YP_001785133.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
YP_001785134.1	TIGRFAM: 6-phosphogluconolactonase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: hso:HS_1652 6-phosphogluconolactonase
YP_001785135.1	KEGG: hso:HS_1653 hypothetical protein
YP_001785136.1	catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate
YP_001785137.1	PFAM: VacJ family lipoprotein; KEGG: hso:HS_1655 VacJ lipoprotein
YP_001785138.1	PFAM: YfbU family protein; KEGG: hso:HS_1656 hypothetical protein
YP_001785139.1	PFAM: protein of unknown function DUF167; KEGG: hso:HS_1657 conserved hypothetical protein
YP_001785140.1	PFAM: protein of unknown function YGGT; KEGG: hso:HS_1658 conserved hypothetical protein
YP_001785141.1	responsible for the influx of magnesium ions
YP_001785142.1	PFAM: protein of unknown function DUF469; KEGG: hso:HS_1661 hypothetical protein
YP_001785143.1	PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: hso:HS_1662 transcription regulator, LysR family
YP_001785144.1	PFAM: phosphoglycerate mutase; KEGG: hso:HS_1664 phosphoglycerate mutase
YP_001785145.1	PFAM: protein of unknown function DUF302; KEGG: hso:HS_1665 hypothetical protein
YP_001785146.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_001785147.1	TIGRFAM: A/G-specific adenine glycosylase; PFAM: HhH-GPD family protein; KEGG: hso:HS_1667 A/G-specific adenine glycosylase
YP_001785148.1	PFAM: Fe(II) trafficking protein YggX; KEGG: hso:HS_1668 hypothetical protein
YP_001785149.1	Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues
YP_001785150.1	PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: hso:HS_1670 phosphomannomutase
YP_001785151.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_001785152.1	TIGRFAM: trimethylamine-N-oxide reductase c-type cytochrome TorC; PFAM: NapC/NirT cytochrome C domain protein; KEGG: hso:HS_1672 cytochrome C protein
YP_001785153.1	TIGRFAM: trimethylamine-N-oxide reductase TorA; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: hso:HS_1673 trimethylamine-N-oxide reductase precursor
YP_001785154.1	TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor
YP_001785155.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_001785156.1	KEGG: hso:HS_1684 Haemophilus-specific protein, uncharacterized
YP_001785157.1	PFAM: protein of unknown function DUF539; KEGG: hso:HS_1685 hypothetical protein
YP_001785158.1	PFAM: ApbE family lipoprotein; KEGG: hso:HS_1686 thiamine biosynthesis lipoprotein
YP_001785159.1	TIGRFAM: peptide methionine sulfoxide reductase; PFAM: methionine sulfoxide reductase A; KEGG: hso:HS_1687 peptide methionine sulfoxide reductase MsrA/MsrB
YP_001785160.1	uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
YP_001785161.1	Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
YP_001785162.1	Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm
YP_001785163.1	uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
YP_001785164.1	uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
YP_001785165.1	uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
YP_001785166.1	PFAM: BolA family protein; KEGG: hso:HS_1694 BolA protein
YP_001785167.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
YP_001785168.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_001785169.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_001785170.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_001785171.1	Produces ATP from ADP in the presence of a proton gradient across the membrane; the subunit delta is part of the catalytic core of the ATP synthase complex
YP_001785172.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.
YP_001785173.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0
YP_001785174.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
YP_001785175.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
YP_001785176.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_001785177.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_001785178.1	PFAM: protein of unknown function DUF904; KEGG: hso:HS_1707 hypothetical protein
YP_001785179.1	negatively supercoils closed circular double-stranded DNA
YP_001785180.1	TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase; HRDC domain protein; DEAD/DEAH box helicase; SMART: DEAD-like helicases; KEGG: hso:HS_1711 ATP-dependent DNA helicase
YP_001785181.1	defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly
YP_001785182.1	KEGG: hit:NTHI0885 hypothetical protein
YP_001785183.1	TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: hso:HS_1713 diaminopimelate decarboxylase
YP_001785184.1	PFAM: sodium:neurotransmitter symporter; KEGG: hso:HS_1714 sodium-dependent transporter (SNF family)
YP_001785185.1	PFAM: TfoX domain protein; KEGG: hso:HS_1715 DNA transformation protein
YP_001785186.1	PFAM: LysR substrate-binding; KEGG: hso:HS_1716 D-serine dehydratase (deaminase) transcriptional activator
YP_001785187.1	PFAM: helix-turn-helix domain protein; peptidase S24 S26A and S26B; KEGG: hdu:HD0089 probable transcription regulator
YP_001785188.1	KEGG: hdu:HD0090  DNA-binding protein
YP_001785189.1	PFAM: Integrase catalytic region; transposase-like Mu; KEGG: sfx:S2951  phage transposase
YP_001785190.1	KEGG: hdu:HD1689  transposase
YP_001785192.1	PFAM: helix-turn-helix domain protein; KEGG: hit:NTHI0420 hypothetical protein
YP_001785193.1	KEGG: hdu:HD1543 hypothetical protein
YP_001785194.1	KEGG: hdu:HD1546 hypothetical protein
YP_001785196.1	PFAM: N-6 DNA methylase; KEGG: fth:FTH_0955 type I site-specific deoxyribonuclease
YP_001785198.1	KEGG: hdu:HD1613 hypothetical protein
YP_001785199.1	KEGG: hso:HS_1709 transposase
YP_001785200.1	KEGG: hdu:HD1611 hypothetical protein
YP_001785201.1	KEGG: bxe:Bxe_A1012 transposase
YP_001785202.1	PFAM: ATPase AAA; SMART: AAA ATPase; KEGG: reu:Reut_C6418 ATPase AAA, central region
YP_001785203.1	PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: reu:Reut_C6419 peptidase S8 and S53, subtilisin, kexin, sedolisin
YP_001785204.1	KEGG: hdu:HD1698 hypothetical protein
YP_001785205.1	PFAM: gluconate transporter; KEGG: hso:HS_1717 D-serine permease
YP_001785206.1	catalyzes the formation of pyruvate from serine
YP_001785207.1	PFAM: Nicotinate phosphoribosyltransferase and related; KEGG: hso:HS_0002 nicotinate phosphoribosyltransferase
YP_001785208.1	catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively
YP_001785209.1	TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: hso:HS_0004 Xaa-His dipeptidase (aminoacyl-histidine dipeptidase)
YP_001785210.1	This protein performs the mismatch recognition step during the DNA repair process
YP_001785211.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_001785212.1	PFAM: SUA5/yciO/yrdC domain; KEGG: hso:HS_0007  translation factor, SUA5 family
YP_001785213.1	PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: hso:HS_0008 DNA topoisomerase I-related protein
YP_001785214.1	PFAM: protein of unknown function DUF179; KEGG: hso:HS_0009 conserved hypothetical protein
YP_001785215.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
YP_001785216.1	PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: hso:HS_0011  transcriptional regulator of sugar metabolism
YP_001785217.1	PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: hso:HS_0012 3-hydroxyisobutyrate dehydrogenase family protein
YP_001785218.1	PFAM: type III effector Hrp-dependent outers; KEGG: hso:HS_0013  secretion system component
YP_001785219.1	PFAM: class II aldolase/adducin family protein; KEGG: hso:HS_0014  L-fuculose-phosphate aldolase, aldolase class II family
YP_001785220.1	PFAM: xylose isomerase; KEGG: hso:HS_0015  hydroxypyruvate isomerase
YP_001785221.1	PFAM: cyclase family protein; KEGG: pmu:PM1362 hypothetical T. maritima
YP_001785222.1	KEGG: pmu:PM1361 kmt1
YP_001785223.1	PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: hso:HS_0016 hypothetical protein
YP_001785224.1	TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter; KEGG: hso:HS_0017 GntP family permease (gluconate uptake protein)
YP_001785225.1	PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: hso:HS_0018 hypothetical protein
YP_001785226.1	PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_0019 permease, major facilitator superfamily
YP_001785227.1	PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: hso:HS_0020 uxu operon regulator
YP_001785228.1	PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: hso:HS_0021 Zn-binding dehydrogenase
YP_001785229.1	TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_0022 dicarboxylate-binding protein
YP_001785230.1	PFAM: tripartite ATP-independent periplasmic transporter DctQ component; KEGG: hso:HS_0023 permease (transporter)
YP_001785231.1	TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_0024 permease (transporter)
YP_001785232.1	PFAM: allophanate hydrolase subunit 1; KEGG: hso:HS_0025 allophanate hydrolase, subunit 1
YP_001785233.1	TIGRFAM: urea amidolyase related protein; PFAM: allophanate hydrolase subunit 2; KEGG: hso:HS_0026 allophanate hydrolase, subunit 2
YP_001785234.1	PFAM: LamB/YcsF family protein; KEGG: hso:HS_0027 lactam utilization protein
YP_001785235.1	KEGG: hso:HS_0028 permease (transporter)
YP_001785236.1	positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose
YP_001785237.1	KEGG: hso:HS_0030 sugar ABC transporter sugar-binding protein
YP_001785238.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0031 sugar ABC transporter ATP-binding
YP_001785239.1	PFAM: inner-membrane translocator; KEGG: hso:HS_0032 sugar ABC transporter permease
YP_001785240.1	PFAM: inner-membrane translocator; KEGG: hso:HS_0033 sugar ABC transporter permease
YP_001785241.1	PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_0034 sugar kinase
YP_001785242.1	TIGRFAM: glutaredoxin-family domain protein; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; glutaredoxin; redoxin; KEGG: hso:HS_0035 peroxiredoxin
YP_001785243.1	Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA
YP_001785244.1	forms homopentamer; channel that opens in response to pressure or hypoosmotic shock
YP_001785245.1	involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain
YP_001785246.1	TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: hso:HS_0039 ribosomal RNA small subunit methyltransferase B
YP_001785247.1	modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth
YP_001785248.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_001785249.1	PFAM: regulatory protein LuxR; response regulator receiver; KEGG: hso:HS_0042 nitrate/nitrite response regulator protein
YP_001785250.1	catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP
YP_001785251.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
YP_001785252.1	PFAM: uroporphyrinogen III synthase HEM4; KEGG: hso:HS_0045 uroporphyrinogen-III synthase
YP_001785253.1	PFAM: protein of unknown function DUF513 hemX; KEGG: hso:HS_0046 uroporphyrin-III C-methyltransferase
YP_001785254.1	TIGRFAM: HemY protein; PFAM: HemY domain protein; KEGG: hso:HS_0047 porphyrin biosynthesis protein
YP_001785255.1	TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase; KEGG: hso:HS_0048 tRNA-dihydrouridine synthase A
YP_001785256.1	PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_0049 sugar kinase, FGGY family
YP_001785257.1	PFAM:  sugar-binding domain protein; KEGG: hso:HS_0050 transcriptional regulator,  sorbitol operon regulator
YP_001785258.1	PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0051 ABC transporter ATP-binding, sugar transport
YP_001785259.1	PFAM: inner-membrane translocator; KEGG: hso:HS_0052 ABC transporter permease, sugar transport
YP_001785260.1	PFAM: inner-membrane translocator; KEGG: hso:HS_0053 ABC transporter permease, sugar transport
YP_001785261.1	KEGG: hso:HS_0054 sugar ABC transporter substrate-binding protein
YP_001785262.1	PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: hso:HS_0055 conserved aldolase
YP_001785263.1	PFAM: antibiotic biosynthesis monooxygenase; KEGG: hso:HS_0056 hypothetical protein
YP_001785264.1	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
YP_001785265.1	PFAM: ribosomal protein S10; KEGG: yps:YPTB3699 30S ribosomal protein S10
YP_001785266.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_001785267.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_001785268.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_001785269.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_001785270.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_001785271.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_001785272.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_001785273.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_001785274.1	one of the stabilizing components for the large ribosomal subunit
YP_001785275.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_001785276.1	PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0069 iron-regulated outer membrane protein
YP_001785277.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_001785278.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_001785279.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_001785280.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif
YP_001785281.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_001785282.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_001785283.1	binds 5S rRNA along with protein L5 and L25
YP_001785284.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_001785285.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
YP_001785286.1	late assembly protein
YP_001785287.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_001785288.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif
YP_001785289.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_001785290.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_001785291.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_001785292.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_001785293.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_001785294.1	PFAM: metallophosphoesterase; KEGG: hso:HS_0086 hypothetical protein
YP_001785295.1	catalyzes the formation of NAD(+) from nicotinamide ribonucleotide
YP_001785296.1	PFAM: protein of unknown function DUF526; KEGG: hso:HS_0088 hypothetical protein
YP_001785297.1	DHBP synthase; functions during riboflavin biosynthesis
YP_001785298.1	involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA
YP_001785299.1	in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]
YP_001785300.1	TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; RelA/SpoT domain protein; KEGG: hso:HS_0095 GTP diphosphokinase (GTP pyrophosphokinase)
YP_001785301.1	PFAM: diacylglycerol kinase; KEGG: hso:HS_0096 diacylglycerol kinase (diglyceride kinase)
YP_001785302.1	TIGRFAM: TonB-dependent lactoferrin and transferrin receptors; TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0582 transferrin binding protein A
YP_001785303.1	KEGG: hso:HS_0104 hypothetical protein
YP_001785304.1	PFAM: beta-ketoacyl synthase; KEGG: hso:HS_0105 3-oxoacyl-[acyl-carrier-protein] synthase (beta-ketoacyl-ACP synthase)
YP_001785305.1	KEGG: hso:HS_0106  dehydratase
YP_001785306.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_001785307.1	PFAM: beta-ketoacyl synthase; KEGG: hso:HS_0108 3-oxoacyl-[acyl-carrier-protein] synthase II
YP_001785308.1	KEGG: hso:HS_0109 hypothetical protein
YP_001785309.1	PFAM: phospholipid/glycerol acyltransferase; KEGG: hso:HS_0110 1-acyl-sn-glycerol-3-phosphate acyltransferase
YP_001785310.1	KEGG: hso:HS_0111 acyl carrier protein
YP_001785311.1	PFAM: phosphopantetheine-binding; KEGG: hso:HS_0112 acyl carrier protein
YP_001785312.1	KEGG: hso:HS_0113 3-hydroxymyristoyl/3-hydroxydecanoyl-[acyl-carrier- protein] dehydratase
YP_001785313.1	KEGG: hso:HS_0114 hypothetical protein
YP_001785314.1	PFAM: AMP-dependent synthetase and ligase; KEGG: hso:HS_0115 conserved acyl-coenzyme A synthetase-related protein
YP_001785315.1	PFAM: glycosyl transferase family 2; KEGG: hso:HS_0116 glycosyl transferase, group 2 family protein
YP_001785316.1	PFAM: lipid A biosynthesis acyltransferase; KEGG: hso:HS_0117  acyltransferase
YP_001785317.1	KEGG: hso:HS_0118 hypothetical protein
YP_001785318.1	KEGG: hso:HS_0119 conserved thioesterase
YP_001785319.1	KEGG: hso:HS_0120 hypothetical protein
YP_001785320.1	KEGG: hso:HS_0121 hypothetical protein
YP_001785321.1	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate
YP_001785322.1	Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway
YP_001785323.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_001785324.1	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine
YP_001785325.1	TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; KEGG: hso:HS_0126 ComE operon protein (competence protein)
YP_001785326.1	TIGRFAM:  endoribonuclease L-PSP; PFAM: endoribonuclease L-PSP; KEGG: hso:HS_0127  translation initiation inhibitor (endoribonuclease L-PSP)
YP_001785327.1	KEGG: hso:HS_0128 hypothetical protein
YP_001785328.1	catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine
YP_001785329.1	catalyzes the formation of anthranilate from chorismate and glutamine; functions in tryptophan biosynthesis
YP_001785330.1	PFAM: ferritin; KEGG: hso:HS_0131 DNA-binding stress protein
YP_001785331.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
YP_001785332.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
YP_001785333.1	PFAM: protein of unknown function DUF37; KEGG: hso:HS_0134 hypothetical protein
YP_001785334.1	protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
YP_001785335.1	in Escherichia coli transcription of this gene is enhanced by polyamines