-- dump date 20140619_105401 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 228400000001 SEQ_END SEQ_END NC_010519.1 2263857 2263857 DR NC_010519.1; contig end 2263857..2263857 Haemophilus somnus 2336 YP_001783356.1 CDS dnaA NC_010519.1 279 1646 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 279..1646 Haemophilus somnus 2336 6108903 YP_001783357.1 CDS HSM_0002 NC_010519.1 1658 2758 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1658..2758 Haemophilus somnus 2336 6106839 YP_001783358.1 CDS recF NC_010519.1 2762 3838 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2762..3838 Haemophilus somnus 2336 6107940 YP_001783359.1 CDS HSM_0004 NC_010519.1 3895 4539 R complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein complement(3895..4539) Haemophilus somnus 2336 6108072 YP_001783360.1 CDS HSM_0005 NC_010519.1 4552 4776 R PFAM: protein of unknown function UPF0270; KEGG: hso:HS_0140 hypothetical protein; hypothetical protein complement(4552..4776) Haemophilus somnus 2336 6108182 YP_001783361.1 CDS slmA NC_010519.1 4811 5470 R FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein complement(4811..5470) Haemophilus somnus 2336 6108290 YP_001783362.1 CDS dut NC_010519.1 5470 5925 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(5470..5925) Haemophilus somnus 2336 6108399 YP_001783363.1 CDS HSM_0008 NC_010519.1 5922 7148 R catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase complement(5922..7148) Haemophilus somnus 2336 6108509 YP_001783364.1 CDS radC NC_010519.1 7321 7989 D Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 7321..7989 Haemophilus somnus 2336 6108619 YP_001783365.1 CDS rpmB NC_010519.1 8210 8446 D required for 70S ribosome assembly; 50S ribosomal protein L28 8210..8446 Haemophilus somnus 2336 6108728 YP_001783366.1 CDS rpmG NC_010519.1 8458 8628 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 8458..8628 Haemophilus somnus 2336 6106840 YP_001783367.1 CDS HSM_0012 NC_010519.1 8734 9546 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 8734..9546 Haemophilus somnus 2336 6106950 YP_001783368.1 CDS HSM_0013 NC_010519.1 9638 11314 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 9638..11314 Haemophilus somnus 2336 6107058 YP_001783369.1 CDS ilvM NC_010519.1 11318 11536 D KEGG: hso:HS_0148 acetohydroxy acid synthase II, small subunit; acetolactate synthase 2 regulatory subunit 11318..11536 Haemophilus somnus 2336 6107168 YP_001783370.1 CDS HSM_0015 NC_010519.1 11602 12264 D PFAM: MOSC domain containing protein; KEGG: hso:HS_0149 hypothetical protein; MOSC domain-containing protein 11602..12264 Haemophilus somnus 2336 6107278 YP_001783371.1 CDS HSM_0016 NC_010519.1 12384 12887 D PFAM: chorismate lyase; KEGG: hso:HS_0150 4-hydroxybenzoate synthetase (chorismate--pyruvate lyase); chorismate lyase 12384..12887 Haemophilus somnus 2336 6107389 YP_001783372.1 CDS HSM_0017 NC_010519.1 12891 15305 D KEGG: hso:HS_0151 exoribonuclease II (ribonuclease R); TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; ribonuclease B OB region domain; ribonuclease R winged-helix domain protein; SMART: Cold shock protein; ribonuclease R 12891..15305 Haemophilus somnus 2336 6107500 YP_001783373.1 CDS HSM_0018 NC_010519.1 15312 16049 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 15312..16049 Haemophilus somnus 2336 6107611 YP_001783374.1 CDS HSM_0019 NC_010519.1 16190 16516 R PFAM: Sel1 domain protein repeat-containing protein; KEGG: hso:HS_0153 conserved hypothetical protein, with TPR repeat (tetratrico peptide repeat); Sel1 domain-containing protein complement(16190..16516) Haemophilus somnus 2336 6107722 YP_001783375.1 CDS cysE NC_010519.1 16560 17357 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(16560..17357) Haemophilus somnus 2336 6107830 YP_001783376.1 CDS gpsA NC_010519.1 17359 18522 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(17359..18522) Haemophilus somnus 2336 6107941 YP_001783377.1 CDS HSM_0022 NC_010519.1 18437 18952 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(18437..18952) Haemophilus somnus 2336 6107973 YP_001783378.1 CDS HSM_0023 NC_010519.1 18963 19409 R PFAM: rhodanese; KEGG: hso:HS_0157 conserved hypothetical protein, with rhodanese-like domain; rhodanese complement(18963..19409) Haemophilus somnus 2336 6107984 YP_001783379.1 CDS HSM_0024 NC_010519.1 19652 20962 D functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 19652..20962 Haemophilus somnus 2336 6107995 YP_001783380.1 CDS ubiA NC_010519.1 21035 21895 R catalyzes the conversion of 4-hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase complement(21035..21895) Haemophilus somnus 2336 6108006 YP_001783381.1 CDS HSM_0026 NC_010519.1 21934 22356 D PFAM: rhodanese; KEGG: hso:HS_0160 thiosulfate sulfurtransferase; rhodanese 21934..22356 Haemophilus somnus 2336 6108017 YP_001783382.1 CDS HSM_0027 NC_010519.1 22380 22694 R KEGG: hso:HS_0161 hypothetical protein; hypothetical protein complement(22380..22694) Haemophilus somnus 2336 6108028 YP_001783383.1 CDS HSM_0028 NC_010519.1 22738 23601 D PFAM: rhomboid family protein; KEGG: hso:HS_0162 GlpG protein, rhomboid family; rhomboid family protein 22738..23601 Haemophilus somnus 2336 6108039 YP_001783384.1 CDS HSM_0029 NC_010519.1 23818 24342 D PFAM: protein of unknown function DUF177; KEGG: hso:HS_0163 conserved hypothetical protein; hypothetical protein 23818..24342 Haemophilus somnus 2336 6108050 YP_001783385.1 CDS rpmF NC_010519.1 24360 24530 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 24360..24530 Haemophilus somnus 2336 6108061 YP_001783386.1 CDS HSM_0031 NC_010519.1 24651 24929 D KEGG: hso:HS_0164 fatty acid/phospholipid synthesis protein; fatty acid/phospholipid synthesis protein 24651..24929 Haemophilus somnus 2336 6108073 YP_001783387.1 CDS HSM_0032 NC_010519.1 24982 25932 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 24982..25932 Haemophilus somnus 2336 6108084 YP_001783388.1 CDS HSM_0033 NC_010519.1 25976 26914 D TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase; KEGG: hso:HS_0166 [acyl-carrier protein] S-malonyltransferase; malonyl CoA-acyl carrier protein transacylase 25976..26914 Haemophilus somnus 2336 6108094 YP_001783389.1 CDS fabG NC_010519.1 26968 27693 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 26968..27693 Haemophilus somnus 2336 6108105 YP_001783390.1 CDS acpP NC_010519.1 27948 28178 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 27948..28178 Haemophilus somnus 2336 6108116 YP_001783391.1 CDS rplK NC_010519.1 28327 28755 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 28327..28755 Haemophilus somnus 2336 6108127 YP_001783392.1 CDS rplA NC_010519.1 28760 29449 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 28760..29449 Haemophilus somnus 2336 6108138 YP_001783393.1 CDS rplJ NC_010519.1 29733 30224 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 29733..30224 Haemophilus somnus 2336 6108149 YP_001783394.1 CDS rplL NC_010519.1 30276 30644 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 30276..30644 Haemophilus somnus 2336 6108160 YP_001783395.1 CDS rho NC_010519.1 30884 32146 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(30884..32146) Haemophilus somnus 2336 6108171 YP_001783396.1 CDS HSM_0041 NC_010519.1 32341 33600 D enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 32341..33600 Haemophilus somnus 2336 6108183 YP_001783397.1 CDS HSM_0042 NC_010519.1 33714 34400 D catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 33714..34400 Haemophilus somnus 2336 6108194 YP_001783398.1 CDS HSM_0043 NC_010519.1 34397 35071 D catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 34397..35071 Haemophilus somnus 2336 6108205 YP_001783399.1 CDS HSM_0044 NC_010519.1 35081 36082 D catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 35081..36082 Haemophilus somnus 2336 6108216 YP_001783400.1 CDS HSM_0045 NC_010519.1 36303 36686 R KEGG: hso:HS_0178 hypothetical protein; hypothetical protein complement(36303..36686) Haemophilus somnus 2336 6108227 YP_001783401.1 CDS HSM_0046 NC_010519.1 36796 37398 D TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; beta-phosphoglucomutase family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hso:HS_0179 phosphatase; beta-phosphoglucomutase family hydrolase 36796..37398 Haemophilus somnus 2336 6108236 YP_001783402.1 CDS HSM_0047 NC_010519.1 37776 40529 R PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0181 TonB-dependent outer membrane receptor; TonB-dependent receptor complement(37776..40529) Haemophilus somnus 2336 6108247 YP_001783403.1 CDS HSM_0048 NC_010519.1 40762 41379 R PFAM: protein of unknown function UPF0126; KEGG: hso:HS_0182 hypothetical protein; hypothetical protein complement(40762..41379) Haemophilus somnus 2336 6108258 YP_001783404.1 CDS HSM_0049 NC_010519.1 41621 43156 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 41621..43156 Haemophilus somnus 2336 6108269 YP_001783405.1 CDS ispH NC_010519.1 43200 44144 R catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase complement(43200..44144) Haemophilus somnus 2336 6108280 YP_001783406.1 CDS lspA NC_010519.1 44144 44641 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(44144..44641) Haemophilus somnus 2336 6108291 YP_001783407.1 CDS HSM_0052 NC_010519.1 45025 45258 D KEGG: hso:HS_1548 outer membrane protein P1; outer membrane protein P1 45025..45258 Haemophilus somnus 2336 6108302 YP_001783408.1 CDS HSM_0053 NC_010519.1 45428 46420 D PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: hso:HS_1548 outer membrane protein P1; aromatic hydrocarbon degradation membrane protein 45428..46420 Haemophilus somnus 2336 6108313 YP_001783409.1 CDS ileS NC_010519.1 46567 49380 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(46567..49380) Haemophilus somnus 2336 6108324 YP_001783410.1 CDS HSM_0055 NC_010519.1 49399 49947 R KEGG: hso:HS_0187 hypothetical protein; hypothetical protein complement(49399..49947) Haemophilus somnus 2336 6108334 YP_001783411.1 CDS HSM_0056 NC_010519.1 50045 50989 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(50045..50989) Haemophilus somnus 2336 6108345 YP_001783412.1 CDS HSM_0057 NC_010519.1 51075 51560 R PFAM: dihydrofolate reductase region; KEGG: hso:HS_0189 dihydrofolate reductase; dihydrofolate reductase complement(51075..51560) Haemophilus somnus 2336 6108356 YP_001783413.1 CDS HSM_0058 NC_010519.1 51613 52077 R KEGG: hso:HS_0190 hypothetical protein; hypothetical protein complement(51613..52077) Haemophilus somnus 2336 6108367 YP_001783414.1 CDS HSM_0059 NC_010519.1 52080 52868 R PFAM: protein of unknown function DUF1212; KEGG: hso:HS_0191 hypothetical protein; hypothetical protein complement(52080..52868) Haemophilus somnus 2336 6108377 YP_001783415.1 CDS HSM_0060 NC_010519.1 53026 54138 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 53026..54138 Haemophilus somnus 2336 6108388 YP_001783416.1 CDS nusG NC_010519.1 54299 54853 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(54299..54853) Haemophilus somnus 2336 6108400 YP_001783417.1 CDS secE NC_010519.1 54855 55262 R forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(54855..55262) Haemophilus somnus 2336 6108410 YP_001783418.1 CDS HSM_0063 NC_010519.1 55438 56622 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(55438..56622) Haemophilus somnus 2336 6108421 YP_001783419.1 CDS HSM_0064 NC_010519.1 57327 58280 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 57327..58280 Haemophilus somnus 2336 6108841 YP_001783420.1 CDS HSM_0065 NC_010519.1 58334 59542 R PFAM: sodium/glutamate symporter; KEGG: hso:HS_0197 sodium/glutamate symporter (glutamate permease); sodium/glutamate symporter complement(58334..59542) Haemophilus somnus 2336 6108443 YP_001783421.1 CDS dnaE NC_010519.1 59724 63200 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(59724..63200) Haemophilus somnus 2336 6108454 YP_001783422.1 CDS HSM_0067 NC_010519.1 63366 65936 R PFAM: ATPase AAA; Clp domain protein; ATPase AAA; ATPase AAA-2 domain protein; SMART: ATPase AAA; KEGG: hso:HS_0199 ATP-dependent Clp protease subunit B; ATPase complement(63366..65936) Haemophilus somnus 2336 6108465 YP_001783423.1 CDS HSM_0068 NC_010519.1 66120 66581 R PFAM: protein of unknown function DUF606; KEGG: hso:HS_0200 hypothetical protein; hypothetical protein complement(66120..66581) Haemophilus somnus 2336 6108476 YP_001783424.1 CDS HSM_0069 NC_010519.1 66765 67022 D catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide; oxaloacetate decarboxylase subunit gamma 66765..67022 Haemophilus somnus 2336 6108487 YP_001783425.1 CDS HSM_0070 NC_010519.1 67035 68834 D catalyzes the formation of pyruvate from oxaloacetate; oxaloacetate decarboxylase 67035..68834 Haemophilus somnus 2336 6108498 YP_001783426.1 CDS HSM_0071 NC_010519.1 68847 70151 D TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase subunit beta; KEGG: hso:HS_0203 oxaloacetate decarboxylase subunit beta; sodium ion-translocating decarboxylase subunit beta 68847..70151 Haemophilus somnus 2336 6108510 YP_001783427.1 CDS HSM_0072 NC_010519.1 70224 71177 R TIGRFAM: transaldolase; PFAM: transaldolase; KEGG: hso:HS_0204 transaldolase; transaldolase B complement(70224..71177) Haemophilus somnus 2336 6108521 YP_001783428.1 CDS HSM_0073 NC_010519.1 71365 73710 D determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 71365..73710 Haemophilus somnus 2336 6108532 YP_001783429.1 CDS HSM_0074 NC_010519.1 73787 74866 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(73787..74866) Haemophilus somnus 2336 6108543 YP_001783430.1 CDS pgk NC_010519.1 74958 76127 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(74958..76127) Haemophilus somnus 2336 6108554 YP_001783431.1 CDS HSM_0076 NC_010519.1 76366 76626 D PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: hso:HS_0208 ferredoxin; 4Fe-4S ferredoxin 76366..76626 Haemophilus somnus 2336 6108565 YP_001783432.1 CDS HSM_0077 NC_010519.1 76675 88866 R PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790 large adhesin; YadA domain-containing protein complement(76675..88866) Haemophilus somnus 2336 6108576 YP_001783433.1 CDS HSM_0078 NC_010519.1 89145 89384 R KEGG: mmu:673901 hypothetical protein LOC673901; hypothetical protein complement(89145..89384) Haemophilus somnus 2336 6108587 YP_001783434.1 CDS HSM_0079 NC_010519.1 89441 90190 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0210 polar amino acid ABC transporter ATP-binding protein; ABC transporter complement(89441..90190) Haemophilus somnus 2336 6108598 YP_001783435.1 CDS HSM_0080 NC_010519.1 90204 90935 R TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0211 amino acid ABC transporter permease; polar amino acid ABC transporter inner membrane subunit complement(90204..90935) Haemophilus somnus 2336 6108609 YP_001783436.1 CDS HSM_0081 NC_010519.1 90910 91692 R PFAM: extracellular solute-binding protein family 3; KEGG: hso:HS_0212 amino acid ABC transporter substrate-binding; extracellular solute-binding protein complement(90910..91692) Haemophilus somnus 2336 6108620 YP_001783437.1 CDS HSM_0082 NC_010519.1 92084 92572 D KEGG: hso:HS_0218 Haemophilus-specific protein, uncharacterized; hypothetical protein 92084..92572 Haemophilus somnus 2336 6108631 YP_001783438.1 CDS HSM_0083 NC_010519.1 92735 94123 R TIGRFAM: anion transporter; PFAM: sodium/sulfate symporter; citrate transporter; KEGG: hso:HS_0219 conserved transporter NadC family; anion transporter complement(92735..94123) Haemophilus somnus 2336 6108642 YP_001783439.1 CDS HSM_0084 NC_010519.1 94307 94807 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(94307..94807) Haemophilus somnus 2336 6108653 YP_001783440.1 CDS HSM_0085 NC_010519.1 94854 95759 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(94854..95759) Haemophilus somnus 2336 6108662 YP_001783441.1 CDS HSM_0086 NC_010519.1 95866 96588 D PFAM: protein of unknown function UPF0066; KEGG: hso:HS_0222 hypothetical protein; hypothetical protein 95866..96588 Haemophilus somnus 2336 6108673 YP_001783442.1 CDS HSM_0087 NC_010519.1 96870 98171 D KEGG: dsy:DSY2532 hypothetical protein; hypothetical protein 96870..98171 Haemophilus somnus 2336 6108684 YP_001783443.1 CDS HSM_0088 NC_010519.1 98140 98292 D KEGG: hso:HS_0222 hypothetical protein; hypothetical protein 98140..98292 Haemophilus somnus 2336 6108695 YP_001783444.1 CDS HSM_0089 NC_010519.1 98452 98871 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 98452..98871 Haemophilus somnus 2336 6108706 YP_001783445.1 CDS HSM_0090 NC_010519.1 98892 100385 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; sugar ABC transporter ATP-binding protein 98892..100385 Haemophilus somnus 2336 6108717 YP_001783446.1 CDS rbsC NC_010519.1 100395 101354 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; sugar ABC transporter permease 100395..101354 Haemophilus somnus 2336 6108729 YP_001783447.1 CDS HSM_0092 NC_010519.1 101383 102261 D periplasmic substrate-binding component of the ATP-dependent ribose transporter; D-ribose transporter subunit RbsB 101383..102261 Haemophilus somnus 2336 6108740 YP_001783448.1 CDS HSM_0093 NC_010519.1 102345 103298 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 102345..103298 Haemophilus somnus 2336 6108751 YP_001783449.1 CDS HSM_0094 NC_010519.1 103319 104329 D PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_0226 ribose operon repressor; alanine racemase 103319..104329 Haemophilus somnus 2336 6108762 YP_001783450.1 CDS HSM_0095 NC_010519.1 104358 104771 R PFAM: SmpA/OmlA domain protein; KEGG: hso:HS_0227 conserved small protein A; SmpA/OmlA domain-containing protein complement(104358..104771) Haemophilus somnus 2336 6108773 YP_001783451.1 CDS HSM_0096 NC_010519.1 104839 105852 R PFAM: 37kDa nucleoid-associated protein; KEGG: hso:HS_0228 nucleoid-associated protein; nucleoid-associated protein NdpA complement(104839..105852) Haemophilus somnus 2336 6108784 YP_001783452.1 CDS HSM_0097 NC_010519.1 105970 106191 D PFAM: protein of unknown function DUF1414; KEGG: hso:HS_0229 hypothetical protein; hypothetical protein 105970..106191 Haemophilus somnus 2336 6108795 YP_001783453.1 CDS HSM_0098 NC_010519.1 106193 107935 D PFAM: sulfatase; KEGG: hso:HS_0230 conserved hypothetical protein; sulfatase 106193..107935 Haemophilus somnus 2336 6108806 YP_001783454.1 CDS HSM_0099 NC_010519.1 108151 108867 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(108151..108867) Haemophilus somnus 2336 6108816 YP_001783455.1 CDS pntA NC_010519.1 109076 110608 D forms a tetramer composed of 2 subunit alphas and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 109076..110608 Haemophilus somnus 2336 6108827 YP_001783456.1 CDS pntB NC_010519.1 110621 112081 D catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 subunit betas; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 110621..112081 Haemophilus somnus 2336 6106841 YP_001783457.1 CDS HSM_0102 NC_010519.1 112162 113811 D PFAM: sulfatase; KEGG: hso:HS_0234 phosphoglycerol transferase; sulfatase 112162..113811 Haemophilus somnus 2336 6106852 YP_001783458.1 CDS mglC NC_010519.1 114180 115190 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein complement(114180..115190) Haemophilus somnus 2336 6106863 YP_001783459.1 CDS HSM_0104 NC_010519.1 115207 116727 R with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein complement(115207..116727) Haemophilus somnus 2336 6106874 YP_001783460.1 CDS HSM_0105 NC_010519.1 116780 117766 R PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: pmu:PM1038 d-galactose binding periplasmic protein precursor; periplasmic binding protein/LacI transcriptional regulator complement(116780..117766) Haemophilus somnus 2336 6106885 YP_001783461.1 CDS HSM_0108 NC_010519.1 119165 120214 D catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 119165..120214 Haemophilus somnus 2336 6106907 YP_001783462.1 CDS HSM_0109 NC_010519.1 120233 121399 D catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 120233..121399 Haemophilus somnus 2336 6106928 YP_001783463.1 CDS galM NC_010519.1 121393 122436 D catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 121393..122436 Haemophilus somnus 2336 6106939 YP_001783464.1 CDS HSM_0111 NC_010519.1 122612 123505 D PFAM: CBS domain containing protein; transporter-associated region; KEGG: hso:HS_0237 magnesium and cobalt efflux protein; hypothetical protein 122612..123505 Haemophilus somnus 2336 6106951 YP_001783465.1 CDS lnt NC_010519.1 123502 125034 D transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 123502..125034 Haemophilus somnus 2336 6106962 YP_001783466.1 CDS HSM_0113 NC_010519.1 125042 125833 R PFAM: TatD-related deoxyribonuclease; KEGG: hso:HS_0239 deoxyribonuclease, TatD family; TatD-related deoxyribonuclease complement(125042..125833) Haemophilus somnus 2336 6106973 YP_001783467.1 CDS HSM_0114 NC_010519.1 126026 126535 R PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: hso:HS_0241 peptidylprolyl isomerase (peptidyl-prolyl cis-trans isomerase); cyclophilin type peptidyl-prolyl cis-trans isomerase complement(126026..126535) Haemophilus somnus 2336 6106984 YP_001783468.1 CDS cysS NC_010519.1 126674 128053 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 126674..128053 Haemophilus somnus 2336 6106995 YP_001783469.1 CDS HSM_0116 NC_010519.1 128105 128848 R PFAM: protein of unknown function DUF208; KEGG: hso:HS_0243 hypothetical protein; hypothetical protein complement(128105..128848) Haemophilus somnus 2336 6107006 YP_001783470.1 CDS HSM_0117 NC_010519.1 128970 129962 R PFAM: polyprenyl synthetase; KEGG: hso:HS_0244 octaprenyl-diphosphate synthase; polyprenyl synthetase complement(128970..129962) Haemophilus somnus 2336 6107017 YP_001783471.1 CDS rplU NC_010519.1 130182 130493 D PFAM: ribosomal protein L21; KEGG: hso:HS_0245 50S ribosomal protein L21; 50S ribosomal protein L21 130182..130493 Haemophilus somnus 2336 6107028 YP_001783472.1 CDS rpmA NC_010519.1 130514 130771 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 130514..130771 Haemophilus somnus 2336 6107038 YP_001783473.1 CDS HSM_0120 NC_010519.1 130907 131827 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: hso:HS_0247 hypothetical protein; hypothetical protein 130907..131827 Haemophilus somnus 2336 6107048 YP_001783474.1 CDS obgE NC_010519.1 131837 133015 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 131837..133015 Haemophilus somnus 2336 6107059 YP_001783475.1 CDS HSM_0122 NC_010519.1 133257 133826 R PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: hso:HS_0249 N-acetyl-anhydromuramyl-L-alanine amidase; N-acetyl-anhydromuranmyl-L-alanine amidase complement(133257..133826) Haemophilus somnus 2336 6107070 YP_001783476.1 CDS HSM_0123 NC_010519.1 133949 134407 D KEGG: hso:HS_0250 fimbrial subunit; fimbrial subunit 133949..134407 Haemophilus somnus 2336 6107081 YP_001783477.1 CDS artP NC_010519.1 134553 135290 D With ArtMQJI transports arginine across the inner membrane; arginine ABC transporter ATP-binding protein 134553..135290 Haemophilus somnus 2336 6107092 YP_001783478.1 CDS HSM_0125 NC_010519.1 135308 136033 D PFAM: extracellular solute-binding protein family 3; KEGG: hso:HS_0252 arginine ABC transporter substrate-binding protein; extracellular solute-binding protein 135308..136033 Haemophilus somnus 2336 6107103 YP_001783479.1 CDS HSM_0126 NC_010519.1 136038 136709 D with ArtPMJI transports arginine across the inner membrane; arginine ABC transporter permease 136038..136709 Haemophilus somnus 2336 6107114 YP_001783480.1 CDS artM NC_010519.1 136720 137403 D with ArtPQJI acts to transport arginine across the inner membrane; arginine ABC transporter permease 136720..137403 Haemophilus somnus 2336 6107125 YP_001783481.1 CDS HSM_0128 NC_010519.1 137509 137796 R KEGG: hso:HS_0255 hypothetical protein; hypothetical protein complement(137509..137796) Haemophilus somnus 2336 6107135 YP_001783482.1 CDS HSM_0129 NC_010519.1 138256 139821 D PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: hso:HS_0256 cytochrome d ubiquinol oxidase subunit I; cytochrome bd ubiquinol oxidase subunit I 138256..139821 Haemophilus somnus 2336 6107146 YP_001783483.1 CDS HSM_0130 NC_010519.1 139836 140972 D TIGRFAM: cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: hso:HS_0257 cytochrome d ubiquinol oxidase subunit II; cytochrome d ubiquinol oxidase subunit II 139836..140972 Haemophilus somnus 2336 6107157 YP_001783484.1 CDS HSM_0131 NC_010519.1 141347 141772 D TIGRFAM: Pol-Pal system-associated acyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: hso:HS_0258 thioesterase; Pol-Pal system-associated acyl-CoA thioesterase 141347..141772 Haemophilus somnus 2336 6107169 YP_001783485.1 CDS HSM_0132 NC_010519.1 141769 142452 D TIGRFAM: Tol-Pal system TolQ; PFAM: MotA/TolQ/ExbB proton channel; KEGG: hso:HS_0259 biopolymer transporter; Tol-Pal system protein TolQ 141769..142452 Haemophilus somnus 2336 6107180 YP_001783486.1 CDS HSM_0133 NC_010519.1 142520 142942 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 142520..142942 Haemophilus somnus 2336 6107191 YP_001783487.1 CDS tolA NC_010519.1 142961 144016 D inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 142961..144016 Haemophilus somnus 2336 6107202 YP_001783488.1 CDS tolB NC_010519.1 144044 145348 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 144044..145348 Haemophilus somnus 2336 6107213 YP_001783489.1 CDS HSM_0136 NC_010519.1 145358 145813 D TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: hso:HS_0263 peptidoglycan-associated outer membrane lipoprotein (outer membrane protein P6); peptidoglycan-associated lipoprotein 145358..145813 Haemophilus somnus 2336 6107223 YP_001783490.1 CDS HSM_0137 NC_010519.1 146488 147015 D KEGG: hso:HS_0264 type II secretory pathway, pseudopilin; type II secretory pathway, pseudopilin 146488..147015 Haemophilus somnus 2336 6108844 YP_001783491.1 CDS HSM_0138 NC_010519.1 147028 147741 D KEGG: hso:HS_0265 hypothetical protein; hypothetical protein 147028..147741 Haemophilus somnus 2336 6107245 YP_001783492.1 CDS HSM_0139 NC_010519.1 147744 148424 D KEGG: hso:HS_0266 hypothetical protein; hypothetical protein 147744..148424 Haemophilus somnus 2336 6107256 YP_001783493.1 CDS HSM_0140 NC_010519.1 148405 148722 D KEGG: hso:HS_0267 hypothetical protein; hypothetical protein 148405..148722 Haemophilus somnus 2336 6107267 YP_001783494.1 CDS HSM_0141 NC_010519.1 148775 152209 D TIGRFAM: exodeoxyribonuclease V, subunit gamma; PFAM: exodeoxyribonuclease V RecC subunit; KEGG: hso:HS_0268 exodeoxyribonuclease V, subunit gamma; exodeoxyribonuclease V subunit gamma 148775..152209 Haemophilus somnus 2336 6107279 YP_001783495.1 CDS ruvA NC_010519.1 152288 152902 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 152288..152902 Haemophilus somnus 2336 6107290 YP_001783496.1 CDS ruvB NC_010519.1 152913 153920 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 152913..153920 Haemophilus somnus 2336 6107301 YP_001783497.1 CDS HSM_0144 NC_010519.1 154034 155242 R PFAM: HI0933 family protein; FAD dependent oxidoreductase; KEGG: hso:HS_0271 conserved hypothetical protein; hypothetical protein complement(154034..155242) Haemophilus somnus 2336 6107312 YP_001783498.1 CDS HSM_0145 NC_010519.1 155242 156207 R TIGRFAM: methyltransferase; PFAM: methyltransferase ; methyltransferase type 11; methyltransferase type 12; KEGG: hso:HS_0272 S-adenosylmethionine-dependent methyltransferase; methyltransferase complement(155242..156207) Haemophilus somnus 2336 6107323 YP_001783499.1 CDS HSM_0146 NC_010519.1 156210 157724 R TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na?? symporter; KEGG: hso:HS_0273 sodium/proline symporter; sodium/proline symporter complement(156210..157724) Haemophilus somnus 2336 6107334 YP_001783500.1 CDS HSM_0147 NC_010519.1 157852 159330 D involved in the processing of the 5'end of 16S rRNA; ribonuclease G 157852..159330 Haemophilus somnus 2336 6107345 YP_001783501.1 CDS HSM_0148 NC_010519.1 159385 160167 D KEGG: hso:HS_0275 glycosyltransferase; glycosyltransferase 159385..160167 Haemophilus somnus 2336 6107356 YP_001783502.1 CDS HSM_0149 NC_010519.1 160305 161753 D PFAM: peptidase U62 modulator of DNA gyrase; KEGG: hso:HS_0276 modulator of DNA gyrase; peptidase U62 modulator of DNA gyrase 160305..161753 Haemophilus somnus 2336 6107367 YP_001783503.1 CDS HSM_0150 NC_010519.1 161967 163415 D PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: hso:HS_0277 SAM-dependent methyltransferase; methyltransferase type 12 161967..163415 Haemophilus somnus 2336 6107378 YP_001783504.1 CDS HSM_0151 NC_010519.1 163496 164302 R PFAM: inositol monophosphatase; KEGG: hso:HS_0278 inositol-1(or 4)-monophosphatase; inositol-phosphate phosphatase complement(163496..164302) Haemophilus somnus 2336 6107390 YP_001783505.1 CDS HSM_0152 NC_010519.1 164474 165214 D TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: hso:HS_0279 tRNA/rRNA methyltransferase; RNA methyltransferase 164474..165214 Haemophilus somnus 2336 6107401 YP_001783506.1 CDS HSM_0153 NC_010519.1 165268 165675 D TIGRFAM: transcriptional regulator, Rrf2 family; iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074; KEGG: hso:HS_0280 transcriptional regulator; BadM/Rrf2 family transcriptional regulator 165268..165675 Haemophilus somnus 2336 6107412 YP_001783507.1 CDS HSM_0154 NC_010519.1 165754 166968 D catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 165754..166968 Haemophilus somnus 2336 6107423 YP_001783508.1 CDS HSM_0155 NC_010519.1 167045 167428 D TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: hso:HS_0282 iron-sulfur cofactor synthesis protein; scaffold protein 167045..167428 Haemophilus somnus 2336 6107434 YP_001783509.1 CDS HSM_0156 NC_010519.1 167594 167917 D TIGRFAM: iron-sulfur cluster assembly accessory protein; iron-sulfur cluster assembly protein IscA; PFAM: HesB/YadR/YfhF-family protein; KEGG: hso:HS_0283 HesB-family protein; iron-sulfur cluster assembly protein IscA 167594..167917 Haemophilus somnus 2336 6107445 YP_001783510.1 CDS hscB NC_010519.1 167930 168448 D J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 167930..168448 Haemophilus somnus 2336 6107456 YP_001783511.1 CDS hscA NC_010519.1 168490 170340 D involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 168490..170340 Haemophilus somnus 2336 6107467 YP_001783512.1 CDS HSM_0159 NC_010519.1 170352 170693 D TIGRFAM: ferredoxin 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: hso:HS_0286 ferredoxin; 2Fe-2S type ferredoxin 170352..170693 Haemophilus somnus 2336 6107478 YP_001783513.1 CDS HSM_0160 NC_010519.1 170828 173101 D Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; bifunctional glutamate--cysteine ligase/glutathione synthetase 170828..173101 Haemophilus somnus 2336 6107489 YP_001783514.1 CDS deoD NC_010519.1 173270 173986 R catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase complement(173270..173986) Haemophilus somnus 2336 6107501 YP_001783515.1 CDS HSM_0162 NC_010519.1 174119 175378 R TIGRFAM: nucleoside transporter; PFAM: Na dependent nucleoside transporter; nucleoside recognition domain protein; Na dependent nucleoside transporter domain protein; KEGG: hso:HS_0289 transporter permease; nucleoside transporter complement(174119..175378) Haemophilus somnus 2336 6107512 YP_001783516.1 CDS HSM_0163 NC_010519.1 175554 176198 D PFAM: protein of unknown function DUF161; KEGG: hso:HS_0290 hypothetical protein; hypothetical protein 175554..176198 Haemophilus somnus 2336 6107523 YP_001783517.1 CDS HSM_0164 NC_010519.1 176275 177843 D PFAM: glycosyl transferase family 2; KEGG: hhe:HH0773 hypothetical protein; glycosyl transferase family protein 176275..177843 Haemophilus somnus 2336 6107534 YP_001783518.1 CDS rpsP NC_010519.1 178024 178272 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 178024..178272 Haemophilus somnus 2336 6107545 YP_001783519.1 CDS rimM NC_010519.1 178299 178826 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 178299..178826 Haemophilus somnus 2336 6107556 YP_001783520.1 CDS trmD NC_010519.1 178880 179617 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 178880..179617 Haemophilus somnus 2336 6107567 YP_001783521.1 CDS rplS NC_010519.1 179653 180003 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 179653..180003 Haemophilus somnus 2336 6107578 YP_001783522.1 CDS HSM_0169 NC_010519.1 180138 180956 R PFAM: esterase; KEGG: hso:HS_0297 hydrolase; esterase complement(180138..180956) Haemophilus somnus 2336 6107589 YP_001783523.1 CDS HSM_0170 NC_010519.1 180993 181994 R PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_0298 gluconate utilization operon repressor; periplasmic binding protein/LacI transcriptional regulator complement(180993..181994) Haemophilus somnus 2336 6107600 YP_001783524.1 CDS HSM_0171 NC_010519.1 182003 183055 R PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: hso:HS_0299 tRNA/rRNA methyltransferase; tRNA/rRNA methyltransferase SpoU complement(182003..183055) Haemophilus somnus 2336 6107612 YP_001783525.1 CDS pssA NC_010519.1 183221 184588 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 183221..184588 Haemophilus somnus 2336 6107623 YP_001783526.1 CDS HSM_0173 NC_010519.1 184618 185328 R PFAM: exonuclease RNase T and DNA polymerase III; SMART: exonuclease; KEGG: hso:HS_0301 DNA polymerase III subunit epsilon; exonuclease RNase T and DNA polymerase III complement(184618..185328) Haemophilus somnus 2336 6107634 YP_001783527.1 CDS HSM_0174 NC_010519.1 185325 187205 R PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294 nucleotidyltransferase KEGG: hso:HS_0302 signal-transduction protein; hypothetical protein complement(185325..187205) Haemophilus somnus 2336 6107645 YP_001783528.1 CDS HSM_0175 NC_010519.1 187307 189217 R PFAM: PfkB domain protein; KEGG: hso:HS_0303 myo-inositol catabolism protein; ribokinase complement(187307..189217) Haemophilus somnus 2336 6107656 YP_001783529.1 CDS HSM_0176 NC_010519.1 189460 190302 D PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: hso:HS_0304 transcriptional regulator; RpiR family transcriptional regulator 189460..190302 Haemophilus somnus 2336 6107667 YP_001783530.1 CDS HSM_0177 NC_010519.1 190339 191103 R PFAM: protein of unknown function DUF548; KEGG: hso:HS_0305 SAM-dependent methyltransferase; hypothetical protein complement(190339..191103) Haemophilus somnus 2336 6107678 YP_001783531.1 CDS HSM_0178 NC_010519.1 191079 192179 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(191079..192179) Haemophilus somnus 2336 6107689 YP_001783532.1 CDS HSM_0179 NC_010519.1 192245 192574 R PFAM: protein of unknown function DUF413; KEGG: hso:HS_0307 hypothetical protein; hypothetical protein complement(192245..192574) Haemophilus somnus 2336 6107700 YP_001783533.1 CDS HSM_0180 NC_010519.1 192628 193236 R PFAM: DSBA oxidoreductase; KEGG: hso:HS_0308 protein disulfide-isomerase (thiol:disulfide interchange protein); DSBA oxidoreductase complement(192628..193236) Haemophilus somnus 2336 6107711 YP_001783534.1 CDS HSM_0181 NC_010519.1 193246 193512 R PFAM: protein of unknown function DUF1040; KEGG: hso:HS_0309 hypothetical protein; hypothetical protein complement(193246..193512) Haemophilus somnus 2336 6107723 YP_001783535.1 CDS mobA NC_010519.1 193579 194166 D in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 193579..194166 Haemophilus somnus 2336 6107734 YP_001783536.1 CDS HSM_0183 NC_010519.1 194285 196291 D TIGRFAM: oligopeptide transporters, OPT superfamily; oligopeptide transporter OPT family; PFAM: oligopeptide transporter OPT superfamily protein; KEGG: hso:HS_0311 integral membrane protein; OPT family oligopeptide transporter 194285..196291 Haemophilus somnus 2336 6107745 YP_001783537.1 CDS HSM_0184 NC_010519.1 196413 197171 R PFAM: Sel1 domain protein repeat-containing protein; KEGG: hso:HS_0313 conserved hypothetical protein, with TPR repeat (tetratrico peptide repeat); Sel1 domain-containing protein complement(196413..197171) Haemophilus somnus 2336 6107755 YP_001783538.1 CDS HSM_0185 NC_010519.1 197193 197456 R KEGG: hso:HS_0314 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(197193..197456) Haemophilus somnus 2336 6107766 YP_001783539.1 CDS HSM_0186 NC_010519.1 197940 198902 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(197940..198902) Haemophilus somnus 2336 6107777 YP_001783540.1 CDS lipB NC_010519.1 198920 199576 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system protein H; lipoate-protein ligase B complement(198920..199576) Haemophilus somnus 2336 6107788 YP_001783541.1 CDS HSM_0188 NC_010519.1 199585 199881 R PFAM: protein of unknown function DUF493; KEGG: hso:HS_0317 hypothetical protein; hypothetical protein complement(199585..199881) Haemophilus somnus 2336 6107799 YP_001783542.1 CDS HSM_0191 NC_010519.1 201211 201771 R TIGRFAM: lipoprotein A; PFAM: Rare lipoprotein A; KEGG: hso:HS_0319 lipoprotein A; lipoprotein A complement(201211..201771) Haemophilus somnus 2336 6107819 YP_001783543.1 CDS HSM_0192 NC_010519.1 201814 202929 R TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: hso:HS_0320 rod shape-determining protein; rod shape-determining protein RodA complement(201814..202929) Haemophilus somnus 2336 6107841 YP_001783544.1 CDS HSM_0193 NC_010519.1 202952 204856 R PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: hso:HS_0321 cell elongation-specific transpeptidase; peptidoglycan glycosyltransferase complement(202952..204856) Haemophilus somnus 2336 6107852 YP_001783545.1 CDS HSM_0194 NC_010519.1 204873 205340 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(204873..205340) Haemophilus somnus 2336 6107863 YP_001783546.1 CDS HSM_0195 NC_010519.1 205360 205668 R TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: hso:HS_0323 hypothetical protein; iojap family protein complement(205360..205668) Haemophilus somnus 2336 6107874 YP_001783547.1 CDS HSM_0196 NC_010519.1 206021 206863 R PFAM: ABC transporter; KEGG: hso:HS_0325 chelated iron ABC transporter permease; ABC transporter complement(206021..206863) Haemophilus somnus 2336 6107885 YP_001783548.1 CDS HSM_0197 NC_010519.1 206856 207746 R PFAM: transporter permease; ABC-3 protein; KEGG: hso:HS_0326 chelated iron ABC transporter permease; ABC transporter complement(206856..207746) Haemophilus somnus 2336 6107896 YP_001783549.1 CDS HSM_0198 NC_010519.1 207751 208509 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0327 iron ABC transporter ATP-binding protein; ABC transporter complement(207751..208509) Haemophilus somnus 2336 6107907 YP_001783550.1 CDS HSM_0199 NC_010519.1 208519 209400 R PFAM: periplasmic solute binding protein; KEGG: hso:HS_0328 chelated iron ABC transporter periplasmic-binding protein; periplasmic solute binding protein complement(208519..209400) Haemophilus somnus 2336 6107918 YP_001783551.1 CDS HSM_0200 NC_010519.1 209506 209835 R PFAM: DsrC family protein; KEGG: hso:HS_0329 sulfite reductase-like protein; DsrC family protein complement(209506..209835) Haemophilus somnus 2336 6107929 YP_001783552.1 CDS HSM_0201 NC_010519.1 209913 210575 R PFAM: protein of unknown function UPF0005; KEGG: hso:HS_0330 conserved integral membrane protein; hypothetical protein complement(209913..210575) Haemophilus somnus 2336 6107942 YP_001783553.1 CDS HSM_0202 NC_010519.1 210983 212512 R TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: hso:HS_0331 competence-related protein; Mg chelatase subunit ChlI complement(210983..212512) Haemophilus somnus 2336 6108845 YP_001783554.1 CDS engB NC_010519.1 212614 213309 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(212614..213309) Haemophilus somnus 2336 6107964 YP_001783555.1 CDS glmU NC_010519.1 213230 214612 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(213230..214612) Haemophilus somnus 2336 6107966 YP_001783556.1 CDS anmK NC_010519.1 214658 215815 D catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 214658..215815 Haemophilus somnus 2336 6107967 YP_001783557.1 CDS murQ NC_010519.1 215818 216729 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 215818..216729 Haemophilus somnus 2336 6107968 YP_001783558.1 CDS HSM_0207 NC_010519.1 217017 217568 D PFAM: NAD(P)H dehydrogenase (quinone); KEGG: hso:HS_0336 NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase (quinone) 217017..217568 Haemophilus somnus 2336 6107969 YP_001783559.1 CDS HSM_0208 NC_010519.1 217835 218533 D KEGG: hso:HS_0337 hypothetical protein; hypothetical protein 217835..218533 Haemophilus somnus 2336 6107970 YP_001783560.1 CDS HSM_0209 NC_010519.1 218615 220303 R uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK complement(218615..220303) Haemophilus somnus 2336 6107971 YP_001783561.1 CDS HSM_0210 NC_010519.1 220629 222389 D PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: hso:HS_0339 conserved outer membrane protein; surface antigen (D15) 220629..222389 Haemophilus somnus 2336 6107972 YP_001783562.1 CDS HSM_0211 NC_010519.1 222400 225927 D PFAM: protein of unknown function DUF490; KEGG: hso:HS_0340 hypothetical protein; hypothetical protein 222400..225927 Haemophilus somnus 2336 6107974 YP_001783563.1 CDS HSM_0212 NC_010519.1 225930 227480 D PFAM: Ppx/GppA phosphatase; KEGG: hso:HS_0341 exopolyphosphatase; Ppx/GppA phosphatase 225930..227480 Haemophilus somnus 2336 6107975 YP_001783564.1 CDS HSM_0213 NC_010519.1 227653 229488 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 227653..229488 Haemophilus somnus 2336 6107976 YP_001783565.1 CDS clpX NC_010519.1 229886 231130 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(229886..231130) Haemophilus somnus 2336 6107977 YP_001783566.1 CDS clpP NC_010519.1 231146 231727 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(231146..231727) Haemophilus somnus 2336 6107978 YP_001783567.1 CDS tig NC_010519.1 231813 233111 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(231813..233111) Haemophilus somnus 2336 6107979 YP_001783568.1 CDS HSM_0217 NC_010519.1 233470 234885 D PFAM: type II secretion system protein E; general secretory system II protein E domain protein; KEGG: hso:HS_1430 pilin/fimbriae biogenesis protein; type II secretion system protein E 233470..234885 Haemophilus somnus 2336 6107980 YP_001783569.1 CDS HSM_0218 NC_010519.1 234919 236178 R PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: hso:HS_1429 transporter; hypothetical protein complement(234919..236178) Haemophilus somnus 2336 6107981 YP_001783570.1 CDS HSM_0219 NC_010519.1 236248 237045 R PFAM: cytochrome C assembly protein; KEGG: hso:HS_1428 permease; cytochrome C assembly protein complement(236248..237045) Haemophilus somnus 2336 6107982 YP_001783571.1 CDS HSM_0220 NC_010519.1 237195 238571 D TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54 helical bundle; SMART: ATPase AAA; KEGG: hso:HS_1427 signal recognition particle protein; signal recognition particle protein 237195..238571 Haemophilus somnus 2336 6107983 YP_001783572.1 CDS HSM_0221 NC_010519.1 238614 240353 R role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM complement(238614..240353) Haemophilus somnus 2336 6107985 YP_001783573.1 CDS HSM_0222 NC_010519.1 240845 241798 D KEGG: hit:NTHI0419 prophage CP4-57-like integrase; prophage CP4-57-like integrase 240845..241798 Haemophilus somnus 2336 6108846 YP_001783574.1 CDS HSM_0223 NC_010519.1 241901 243037 R TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: hso:HS_0583 transposase; IS605 family transposase OrfB complement(241901..243037) Haemophilus somnus 2336 6107987 YP_001783575.1 CDS HSM_0224 NC_010519.1 243084 243500 D PFAM: transposase IS200-family protein; KEGG: hso:HS_0666 transposase; transposase IS200-family protein 243084..243500 Haemophilus somnus 2336 6107988 YP_001783576.1 CDS HSM_0225 NC_010519.1 243787 244248 R hypothetical protein complement(243787..244248) Haemophilus somnus 2336 6107989 YP_001783577.1 CDS HSM_0226 NC_010519.1 244245 244697 R PFAM: phage head completion; KEGG: spt:SPA2617 phage gene; phage head completion complement(244245..244697) Haemophilus somnus 2336 6107990 YP_001783578.1 CDS HSM_0227 NC_010519.1 244690 245571 R PFAM: phage small terminase subunit; KEGG: yps:YPTB3143 hypothetical protein; phage small terminase subunit complement(244690..245571) Haemophilus somnus 2336 6107991 YP_001783579.1 CDS HSM_0228 NC_010519.1 245600 246631 R TIGRFAM: phage major capsid protein, P2 family; PFAM: phage major capsid protein P2; KEGG: pat:Patl_0697 phage major capsid protein, P2 family; P2 family phage major capsid protein complement(245600..246631) Haemophilus somnus 2336 6107992 YP_001783580.1 CDS HSM_0229 NC_010519.1 246641 247066 R hypothetical protein complement(246641..247066) Haemophilus somnus 2336 6107993 YP_001783581.1 CDS HSM_0230 NC_010519.1 247017 247538 R PFAM: phage capsid scaffolding; KEGG: hch:HCH_00395 flagellar biosynthesis/type III secretory pathway protein; phage capsid scaffolding complement(247017..247538) Haemophilus somnus 2336 6107994 YP_001783582.1 CDS HSM_0231 NC_010519.1 247701 249488 D PFAM: protein of unknown function DUF264; terminase ATPase; KEGG: yps:YPTB3140 [Haemophilus phage HP1] orf16-like phage protein; hypothetical protein 247701..249488 Haemophilus somnus 2336 6107996 YP_001783583.1 CDS HSM_0232 NC_010519.1 249499 250527 D TIGRFAM: phage portal protein, PBSX family; PFAM: phage portal protein; KEGG: sgl:SG0244 phage capsid portal protein; PBSX family phage portal protein 249499..250527 Haemophilus somnus 2336 6107997 YP_001783584.1 CDS HSM_0233 NC_010519.1 250583 250861 D PFAM: phage transcriptional activator Ogr/delta; KEGG: yps:YPTB3138 (AB008550) orf34 [bacteriophage phi CTX]; phage transcriptional activator Ogr/delta 250583..250861 Haemophilus somnus 2336 6107998 YP_001783585.1 CDS HSM_0234 NC_010519.1 250962 251357 R hypothetical protein complement(250962..251357) Haemophilus somnus 2336 6107999 YP_001783586.1 CDS HSM_0235 NC_010519.1 251354 252739 R PFAM: N-6 DNA methylase; KEGG: ldb:Ldb1052 type I restriction-modification system, modification subunit; N-6 DNA methylase complement(251354..252739) Haemophilus somnus 2336 6108000 YP_001783587.1 CDS HSM_0236 NC_010519.1 252756 253286 R hypothetical protein complement(252756..253286) Haemophilus somnus 2336 6108001 YP_001783588.1 CDS HSM_0237 NC_010519.1 253301 255490 R KEGG: pmu:PM1782 unknown; hypothetical protein complement(253301..255490) Haemophilus somnus 2336 6108002 YP_001783589.1 CDS HSM_0238 NC_010519.1 255487 255756 R hypothetical protein complement(255487..255756) Haemophilus somnus 2336 6108003 YP_001783590.1 CDS HSM_0239 NC_010519.1 255749 256237 R KEGG: hso:HS_0528 hypothetical protein; hypothetical protein complement(255749..256237) Haemophilus somnus 2336 6108004 YP_001783591.1 CDS HSM_0240 NC_010519.1 256389 256667 R KEGG: hso:HS_0527 hypothetical protein; hypothetical protein complement(256389..256667) Haemophilus somnus 2336 6108005 YP_001783592.1 CDS HSM_0241 NC_010519.1 256736 257500 R PFAM: DNA methylase N-4/N-6 domain protein; KEGG: hit:NTHI1495 modification methylase DpnIIB-like; DNA methylase N-4/N-6 domain-containing protein complement(256736..257500) Haemophilus somnus 2336 6108007 YP_001783593.1 CDS HSM_0242 NC_010519.1 257511 257972 R KEGG: pmu:PM1778 unknown; hypothetical protein complement(257511..257972) Haemophilus somnus 2336 6108008 YP_001783594.1 CDS HSM_0243 NC_010519.1 258443 258724 R hypothetical protein complement(258443..258724) Haemophilus somnus 2336 6108009 YP_001783595.1 CDS HSM_0244 NC_010519.1 258693 258962 R hypothetical protein complement(258693..258962) Haemophilus somnus 2336 6108010 YP_001783596.1 CDS HSM_0245 NC_010519.1 259257 259694 D KEGG: vei:Veis_1323 hypothetical protein; hypothetical protein 259257..259694 Haemophilus somnus 2336 6108011 YP_001783597.1 CDS HSM_0246 NC_010519.1 261096 261314 R hypothetical protein complement(261096..261314) Haemophilus somnus 2336 6108012 YP_001783598.1 CDS HSM_0247 NC_010519.1 262158 262610 R KEGG: nma:NMA1837 hypothetical protein; hypothetical protein complement(262158..262610) Haemophilus somnus 2336 6108013 YP_001783599.1 CDS HSM_0248 NC_010519.1 262646 263011 R KEGG: nma:NMA1838 hypothetical DNA-binding protein; DNA-binding protein complement(262646..263011) Haemophilus somnus 2336 6108014 YP_001783600.1 CDS HSM_0249 NC_010519.1 263373 263696 D TIGRFAM: Addiction module killer protein HI1419; PFAM: protein of unknown function DUF891; KEGG: bxe:Bxe_B0862 hypothetical protein; addiction module killer protein 263373..263696 Haemophilus somnus 2336 6108015 YP_001783601.1 CDS HSM_0250 NC_010519.1 263689 263988 D TIGRFAM: Addiction module antidote protein HI1420; KEGG: pfo:Pfl_2007 predicted transcriptional regulator; transcriptional regulator 263689..263988 Haemophilus somnus 2336 6108016 YP_001783602.1 CDS HSM_0251 NC_010519.1 264628 265488 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 264628..265488 Haemophilus somnus 2336 6108018 YP_001783603.1 CDS HSM_0252 NC_010519.1 265555 266385 D PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: hso:HS_1363 hypothetical protein; NAD-dependent epimerase/dehydratase 265555..266385 Haemophilus somnus 2336 6108019 YP_001783604.1 CDS HSM_0253 NC_010519.1 266479 267813 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 266479..267813 Haemophilus somnus 2336 6108020 YP_001783605.1 CDS HSM_0254 NC_010519.1 267923 268810 D PFAM: protein of unknown function DUF535; KEGG: hso:HS_1361 hypothetical protein; hypothetical protein 267923..268810 Haemophilus somnus 2336 6108021 YP_001783606.1 CDS fabZ NC_010519.1 268893 269348 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 268893..269348 Haemophilus somnus 2336 6108022 YP_001783607.1 CDS HSM_0256 NC_010519.1 269362 270150 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 269362..270150 Haemophilus somnus 2336 6108023 YP_001783608.1 CDS lpxB NC_010519.1 270232 271401 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 270232..271401 Haemophilus somnus 2336 6108024 YP_001783609.1 CDS rnhB NC_010519.1 271402 272037 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 271402..272037 Haemophilus somnus 2336 6108025 YP_001783610.1 CDS mogA NC_010519.1 272098 272682 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 272098..272682 Haemophilus somnus 2336 6108026 YP_001783611.1 CDS HSM_0260 NC_010519.1 272725 273063 D PFAM: nitrogen regulatory protein P-II; KEGG: hso:HS_1355 nitrogen regulatory protein p-II; nitrogen regulatory protein P-II 272725..273063 Haemophilus somnus 2336 6108027 YP_001783612.1 CDS HSM_0261 NC_010519.1 273063 274115 D PFAM: protein of unknown function UPF0118; KEGG: hso:HS_1354 permease; hypothetical protein 273063..274115 Haemophilus somnus 2336 6108029 YP_001783613.1 CDS HSM_0262 NC_010519.1 274430 275383 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(274430..275383) Haemophilus somnus 2336 6108030 YP_001783614.1 CDS HSM_0263 NC_010519.1 275468 275974 D PFAM: Smr protein/MutS2; KEGG: hso:HS_1352 hypothetical protein; hypothetical protein 275468..275974 Haemophilus somnus 2336 6108031 YP_001783615.1 CDS HSM_0264 NC_010519.1 275976 278141 R TIGRFAM: hypothetical membrane protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: hso:HS_1351 membrane protein; hypothetical protein complement(275976..278141) Haemophilus somnus 2336 6108032 YP_001783616.1 CDS mgsA NC_010519.1 278166 278624 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(278166..278624) Haemophilus somnus 2336 6108033 YP_001783617.1 CDS HSM_0266 NC_010519.1 278689 279342 R KEGG: hso:HS_1349 hypothetical protein; hypothetical protein complement(278689..279342) Haemophilus somnus 2336 6108034 YP_001783618.1 CDS HSM_0267 NC_010519.1 279733 281478 D PFAM: Hemolysin activator HlyB domain protein; polypeptide-transport-associated domain protein ShlB-type; KEGG: msu:MS1169 FhaC protein; polypeptide-transport-associated domain-containing protein 279733..281478 Haemophilus somnus 2336 6108035 YP_001783619.1 CDS HSM_0268 NC_010519.1 281512 288630 D TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: nme:NMB1768 hemagglutinin/hemolysin-related protein; filamentous hemagglutinin outer membrane protein 281512..288630 Haemophilus somnus 2336 6108036 YP_001783620.1 CDS HSM_0269 NC_010519.1 288599 288940 D KEGG: nme:NMB1764 hypothetical protein; hypothetical protein 288599..288940 Haemophilus somnus 2336 6108037 YP_001783621.1 CDS HSM_0270 NC_010519.1 289047 292526 D KEGG: nme:NMB1768 hemagglutinin/hemolysin-related protein; hemagglutinin/hemolysin-like protein 289047..292526 Haemophilus somnus 2336 6108038 YP_001783622.1 CDS HSM_0271 NC_010519.1 292546 293073 D KEGG: nme:NMB1502 hypothetical protein; hypothetical protein 292546..293073 Haemophilus somnus 2336 6108040 YP_001783623.1 CDS HSM_0272 NC_010519.1 293222 294907 D KEGG: msu:MS1162 hypothetical protein; hypothetical protein 293222..294907 Haemophilus somnus 2336 6108041 YP_001783624.1 CDS HSM_0273 NC_010519.1 294885 295271 D hypothetical protein 294885..295271 Haemophilus somnus 2336 6108042 YP_001783625.1 CDS HSM_0274 NC_010519.1 295335 296903 D KEGG: mfa:Mfla_0483 adhesin HecA 20-residue repeat X2; adhesin 295335..296903 Haemophilus somnus 2336 6108043 YP_001783626.1 CDS HSM_0275 NC_010519.1 296905 297255 D hypothetical protein 296905..297255 Haemophilus somnus 2336 6108044 YP_001783627.1 CDS HSM_0276 NC_010519.1 297372 297707 D hypothetical protein 297372..297707 Haemophilus somnus 2336 6108045 YP_001783628.1 CDS HSM_0277 NC_010519.1 298438 299547 D catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity; cystathionine gamma-synthase 298438..299547 Haemophilus somnus 2336 6108849 YP_001783629.1 CDS HSM_0278 NC_010519.1 299712 300035 D TIGRFAM: thioredoxin; PFAM: thioredoxin domain; KEGG: hso:HS_1344 thioredoxin; thioredoxin 299712..300035 Haemophilus somnus 2336 6108047 YP_001783630.1 CDS HSM_0279 NC_010519.1 300153 300848 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(300153..300848) Haemophilus somnus 2336 6108048 YP_001783631.1 CDS HSM_0280 NC_010519.1 300935 302176 R TIGRFAM: uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease; KEGG: hso:HS_1342 uracil permease; uracil-xanthine permease complement(300935..302176) Haemophilus somnus 2336 6108049 YP_001783632.1 CDS upp NC_010519.1 302278 302904 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(302278..302904) Haemophilus somnus 2336 6108051 YP_001783633.1 CDS HSM_0282 NC_010519.1 303044 303871 R PFAM: glutamine amidotransferase class-II; KEGG: hso:HS_1340 conserved hypothetical protein; glutamine amidotransferase complement(303044..303871) Haemophilus somnus 2336 6108052 YP_001783634.1 CDS HSM_0283 NC_010519.1 304065 305414 R converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase complement(304065..305414) Haemophilus somnus 2336 6108053 YP_001783635.1 CDS HSM_0284 NC_010519.1 305820 306425 D KEGG: hso:HS_1338 hypothetical protein; hypothetical protein 305820..306425 Haemophilus somnus 2336 6108054 YP_001783636.1 CDS HSM_0285 NC_010519.1 307235 309025 R PFAM: glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: hso:HS_1330 beta-glucuronidase; beta-D-glucuronidase complement(307235..309025) Haemophilus somnus 2336 6108055 YP_001783637.1 CDS HSM_0286 NC_010519.1 309047 310075 R PFAM: PfkB domain protein; KEGG: hso:HS_1329 2-keto-3-deoxygluconate kinase; ribokinase-like domain-containing protein complement(309047..310075) Haemophilus somnus 2336 6108056 YP_001783638.1 CDS HSM_0287 NC_010519.1 310576 311874 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 310576..311874 Haemophilus somnus 2336 6108057 YP_001783639.1 CDS HSM_0288 NC_010519.1 311940 313292 R PFAM: peptidase U62 modulator of DNA gyrase; KEGG: hso:HS_1327 antibiotic maturation factor; peptidase U62 modulator of DNA gyrase complement(311940..313292) Haemophilus somnus 2336 6108058 YP_001783640.1 CDS HSM_0289 NC_010519.1 313439 313972 D PFAM: protein of unknown function DUF615; KEGG: hso:HS_1326 hypothetical protein; hypothetical protein 313439..313972 Haemophilus somnus 2336 6108059 YP_001783641.1 CDS engA NC_010519.1 314103 315638 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 314103..315638 Haemophilus somnus 2336 6108060 YP_001783642.1 CDS HSM_0291 NC_010519.1 315806 316615 D catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA; DNA ligase 315806..316615 Haemophilus somnus 2336 6108062 YP_001783643.1 CDS HSM_0292 NC_010519.1 316757 318133 D PFAM: peptidase U32; KEGG: hso:HS_1323 collagenase PrtC; peptidase U32 316757..318133 Haemophilus somnus 2336 6108063 YP_001783644.1 CDS HSM_0293 NC_010519.1 318444 318632 R KEGG: hso:HS_1322 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(318444..318632) Haemophilus somnus 2336 6108064 YP_001783645.1 CDS HSM_0294 NC_010519.1 318641 318913 R KEGG: hso:HS_1321 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(318641..318913) Haemophilus somnus 2336 6108065 YP_001783646.1 CDS HSM_0295 NC_010519.1 318940 319335 D hypothetical protein 318940..319335 Haemophilus somnus 2336 6108066 YP_001783647.1 CDS HSM_0296 NC_010519.1 319678 319806 D KEGG: hso:HS_1320 Haemophilus-specific protein, uncharacterized; hypothetical protein 319678..319806 Haemophilus somnus 2336 6108067 YP_001783648.1 CDS HSM_0297 NC_010519.1 320118 320258 D KEGG: hso:HS_1319 C4-dicarboxylate transporter, C4-dicarboxylate-binding protein; hypothetical protein 320118..320258 Haemophilus somnus 2336 6108068 YP_001783649.1 CDS HSM_0298 NC_010519.1 320321 321193 D PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_1319 C4-dicarboxylate transporter, C4-dicarboxylate-binding protein; TRAP dicarboxylate transporter subunit DctP 320321..321193 Haemophilus somnus 2336 6108069 YP_001783650.1 CDS HSM_0299 NC_010519.1 321190 321642 D PFAM: tripartite ATP-independent periplasmic transporter DctQ component; KEGG: hso:HS_1318 C4-dicarboxylate transporter, small subunit; tripartite ATP-independent periplasmic transporter DctQ 321190..321642 Haemophilus somnus 2336 6108070 YP_001783651.1 CDS HSM_0300 NC_010519.1 321660 322928 D TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: citrate transporter; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_1317 C4-dicarboxylate transporter, large subunit (permease); TRAP dicarboxylate transporter subunit DctM 321660..322928 Haemophilus somnus 2336 6108071 YP_001783652.1 CDS queA NC_010519.1 323060 324130 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 323060..324130 Haemophilus somnus 2336 6108074 YP_001783653.1 CDS tgt NC_010519.1 324175 325311 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 324175..325311 Haemophilus somnus 2336 6108075 YP_001783654.1 CDS yajC NC_010519.1 325467 325766 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 325467..325766 Haemophilus somnus 2336 6108076 YP_001783655.1 CDS secD NC_010519.1 325798 327648 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 325798..327648 Haemophilus somnus 2336 6108077 YP_001783656.1 CDS secF NC_010519.1 327661 328629 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 327661..328629 Haemophilus somnus 2336 6108078 YP_001783657.1 CDS secG NC_010519.1 329205 329549 R TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: hso:HS_1311 protein-export membrane protein; preprotein translocase subunit SecG complement(329205..329549) Haemophilus somnus 2336 6108850 YP_001783658.1 CDS HSM_0307 NC_010519.1 329687 331585 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(329687..331585) Haemophilus somnus 2336 6108080 YP_001783659.1 CDS HSM_0308 NC_010519.1 331711 332040 D PFAM: conserved hypothetical protein 103; KEGG: hso:HS_1309 hypothetical protein; hypothetical protein 331711..332040 Haemophilus somnus 2336 6108081 YP_001783660.1 CDS recR NC_010519.1 332103 332708 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 332103..332708 Haemophilus somnus 2336 6108082 YP_001783661.1 CDS HSM_0310 NC_010519.1 332756 333943 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(332756..333943) Haemophilus somnus 2336 6108083 YP_001783662.1 CDS HSM_0313 NC_010519.1 336349 338064 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(336349..338064) Haemophilus somnus 2336 6108086 YP_001783663.1 CDS recX NC_010519.1 338166 338630 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(338166..338630) Haemophilus somnus 2336 6108087 YP_001783664.1 CDS recA NC_010519.1 338739 339806 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(338739..339806) Haemophilus somnus 2336 6108088 YP_001783665.1 CDS HSM_0316 NC_010519.1 339930 341849 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1302 ABC transporter ATP-binding protein; ABC transporter complement(339930..341849) Haemophilus somnus 2336 6108089 YP_001783666.1 CDS HSM_0317 NC_010519.1 342092 342724 R PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: hso:HS_1301 FKBP-type peptidyl-prolyl cis-trans isomerase; FKBP-type peptidylprolyl isomerase complement(342092..342724) Haemophilus somnus 2336 6108090 YP_001783667.1 CDS psd NC_010519.1 342751 343635 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(342751..343635) Haemophilus somnus 2336 6108091 YP_001783668.1 CDS xerC NC_010519.1 343932 344819 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 343932..344819 Haemophilus somnus 2336 6108092 YP_001783669.1 CDS HSM_0320 NC_010519.1 344868 345236 R TIGRFAM: dihydroneopterin aldolase; KEGG: hso:HS_1298 dihydroneopterin aldolase; dihydroneopterin aldolase complement(344868..345236) Haemophilus somnus 2336 6108093 YP_001783670.1 CDS HSM_0321 NC_010519.1 345332 345913 D PFAM: protein of unknown function DUF205; KEGG: hso:HS_1297 conserved hypothetical protein; hypothetical protein 345332..345913 Haemophilus somnus 2336 6108095 YP_001783671.1 CDS HSM_0322 NC_010519.1 345930 346640 R PFAM: methyltransferase small; KEGG: hso:HS_1296 SAM-dependent methyltransferase; methyltransferase small complement(345930..346640) Haemophilus somnus 2336 6108096 YP_001783672.1 CDS HSM_0323 NC_010519.1 346723 348057 D facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 346723..348057 Haemophilus somnus 2336 6108097 YP_001783673.1 CDS HSM_0324 NC_010519.1 348094 348927 R PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: hso:HS_1294 conserved hypothetical protein; glycine cleavage T protein (aminomethyl transferase) complement(348094..348927) Haemophilus somnus 2336 6108098 YP_001783674.1 CDS HSM_0325 NC_010519.1 348936 349799 R PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: hso:HS_1293 hypothetical protein; hypothetical protein complement(348936..349799) Haemophilus somnus 2336 6108099 YP_001783675.1 CDS rph NC_010519.1 349920 350636 D RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 349920..350636 Haemophilus somnus 2336 6108100 YP_001783676.1 CDS djlA NC_010519.1 350729 351598 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 350729..351598 Haemophilus somnus 2336 6108101 YP_001783677.1 CDS HSM_0328 NC_010519.1 351603 352532 D PFAM: dihydrouridine synthase; KEGG: hso:HS_1290 tRNA-dihydrouridine synthase C; dihydrouridine synthase 351603..352532 Haemophilus somnus 2336 6108102 YP_001783678.1 CDS HSM_0329 NC_010519.1 352579 353145 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(352579..353145) Haemophilus somnus 2336 6108103 YP_001783679.1 CDS HSM_0330 NC_010519.1 353181 354194 D TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: radical SAM protein; KEGG: hso:HS_1288 hypothetical protein; lysine 2,3-aminomutase YodO family protein 353181..354194 Haemophilus somnus 2336 6108104 YP_001783680.1 CDS HSM_0331 NC_010519.1 354288 355451 D PFAM: Opacity-associated protein A; KEGG: hso:HS_1287 opacity associated protein A; opacity-associated protein A 354288..355451 Haemophilus somnus 2336 6108106 YP_001783681.1 CDS rdgC NC_010519.1 355519 356424 R Required for efficient pilin antigenic variation; recombination associated protein complement(355519..356424) Haemophilus somnus 2336 6108107 YP_001783682.1 CDS HSM_0333 NC_010519.1 356487 357302 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 356487..357302 Haemophilus somnus 2336 6108108 YP_001783683.1 CDS HSM_0334 NC_010519.1 357303 358502 D transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 357303..358502 Haemophilus somnus 2336 6108109 YP_001783684.1 CDS xerD NC_010519.1 358499 359392 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 358499..359392 Haemophilus somnus 2336 6108110 YP_001783685.1 CDS HSM_0336 NC_010519.1 359502 360248 D KEGG: hso:HS_0337 hypothetical protein; hypothetical protein 359502..360248 Haemophilus somnus 2336 6108111 YP_001783686.1 CDS HSM_0337 NC_010519.1 360404 361150 D KEGG: hso:HS_0337 hypothetical protein; hypothetical protein 360404..361150 Haemophilus somnus 2336 6108112 YP_001783687.1 CDS HSM_0338 NC_010519.1 361328 368587 R PFAM: YadA domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790 large adhesin; YadA domain-containing protein complement(361328..368587) Haemophilus somnus 2336 6108113 YP_001783688.1 CDS HSM_0339 NC_010519.1 369103 369891 R KEGG: hso:HS_1184 hypothetical protein; hypothetical protein complement(369103..369891) Haemophilus somnus 2336 6108114 YP_001783689.1 CDS HSM_0340 NC_010519.1 370048 370764 D PFAM: hypothetical protein; KEGG: hso:HS_1183 permease; hypothetical protein 370048..370764 Haemophilus somnus 2336 6108115 YP_001783690.1 CDS HSM_0341 NC_010519.1 370807 372219 R PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: hso:HS_1548 outer membrane protein P1; aromatic hydrocarbon degradation membrane protein complement(370807..372219) Haemophilus somnus 2336 6108117 YP_001783691.1 CDS HSM_0342 NC_010519.1 372565 373293 D TIGRFAM: molybdenum ABC transporter periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_1182 molybdenum ABC transporter periplasmic binding protein; molybdenum ABC transporter periplasmic molybdate-binding protein 372565..373293 Haemophilus somnus 2336 6108118 YP_001783692.1 CDS modB NC_010519.1 373299 374009 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 373299..374009 Haemophilus somnus 2336 6108119 YP_001783693.1 CDS HSM_0344 NC_010519.1 374110 377070 D catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 374110..377070 Haemophilus somnus 2336 6108120 YP_001783694.1 CDS HSM_0345 NC_010519.1 377185 377850 D KEGG: hso:HS_1217 hypothetical protein; hypothetical protein 377185..377850 Haemophilus somnus 2336 6108121 YP_001783695.1 CDS HSM_0346 NC_010519.1 378185 382837 R PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0209 large adhesin; YadA domain-containing protein complement(378185..382837) Haemophilus somnus 2336 6108122 YP_001783696.1 CDS xseA NC_010519.1 383421 384755 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 383421..384755 Haemophilus somnus 2336 6108123 YP_001783697.1 CDS HSM_0348 NC_010519.1 384808 385542 R PFAM: alanine racemase domain protein; KEGG: hso:HS_1215 hypothetical protein; alanine racemase complement(384808..385542) Haemophilus somnus 2336 6108124 YP_001783698.1 CDS thrA NC_010519.1 385832 388282 D multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 385832..388282 Haemophilus somnus 2336 6108125 YP_001783699.1 CDS HSM_0350 NC_010519.1 388295 389239 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 388295..389239 Haemophilus somnus 2336 6108126 YP_001783700.1 CDS HSM_0351 NC_010519.1 389252 390529 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 389252..390529 Haemophilus somnus 2336 6108128 YP_001783701.1 CDS HSM_0352 NC_010519.1 390701 391147 R PFAM: ferric-uptake regulator; KEGG: hso:HS_1211 ferric uptake regulation protein; ferric uptake regulator family protein complement(390701..391147) Haemophilus somnus 2336 6108129 YP_001783702.1 CDS HSM_0353 NC_010519.1 391164 391688 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(391164..391688) Haemophilus somnus 2336 6108130 YP_001783703.1 CDS HSM_0354 NC_010519.1 392110 392889 R PFAM: alpha/beta hydrolase; PGAP1 family protein; KEGG: hso:HS_1209 esterase/lipase; alpha/beta hydrolase complement(392110..392889) Haemophilus somnus 2336 6108131 YP_001783704.1 CDS HSM_0355 NC_010519.1 392995 393609 D negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 392995..393609 Haemophilus somnus 2336 6108132 YP_001783705.1 CDS HSM_0356 NC_010519.1 393612 395018 D TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: hso:HS_1207 O-succinylbenzoic acid--CoA ligase; O-succinylbenzoic acid--CoA ligase 393612..395018 Haemophilus somnus 2336 6108133 YP_001783706.1 CDS HSM_0357 NC_010519.1 395021 398317 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 395021..398317 Haemophilus somnus 2336 6108134 YP_001783707.1 CDS HSM_0358 NC_010519.1 398333 399415 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 398333..399415 Haemophilus somnus 2336 6108135 YP_001783708.1 CDS mepA NC_010519.1 399448 400287 D D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 399448..400287 Haemophilus somnus 2336 6108136 YP_001783709.1 CDS HSM_0360 NC_010519.1 400298 401068 D PFAM: protein of unknown function DUF81; KEGG: hso:HS_1203 conserved hypothetical protein; hypothetical protein 400298..401068 Haemophilus somnus 2336 6108137 YP_001783710.1 CDS HSM_0361 NC_010519.1 401092 402045 D transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 401092..402045 Haemophilus somnus 2336 6108139 YP_001783711.1 CDS HSM_0362 NC_010519.1 402116 402655 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 402116..402655 Haemophilus somnus 2336 6108140 YP_001783712.1 CDS HSM_0363 NC_010519.1 402686 404689 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma/tau 402686..404689 Haemophilus somnus 2336 6108141 YP_001783713.1 CDS HSM_0364 NC_010519.1 404942 406060 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 404942..406060 Haemophilus somnus 2336 6108142 YP_001783714.1 CDS HSM_0365 NC_010519.1 406091 406630 D TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: hypothetical protein; Tetratricopeptide TPR_2 repeat protein; SMART: hypothetical protein; KEGG: hso:HS_1197 fimbrial biogenesis and twitching motility protein; type IV pilus biogenesis/stability protein PilW 406091..406630 Haemophilus somnus 2336 6108143 YP_001783715.1 CDS HSM_0366 NC_010519.1 406713 408983 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(406713..408983) Haemophilus somnus 2336 6108144 YP_001783716.1 CDS HSM_0367 NC_010519.1 409267 410388 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(409267..410388) Haemophilus somnus 2336 6108145 YP_001783717.1 CDS dnaK NC_010519.1 410486 412393 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(410486..412393) Haemophilus somnus 2336 6108146 YP_001783718.1 CDS HSM_0369 NC_010519.1 412572 413825 R PFAM: polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; KEGG: hso:HS_1193 tRNA nucleotidyltransferase; polynucleotide adenylyltransferase/metal dependent phosphohydrolase complement(412572..413825) Haemophilus somnus 2336 6108147 YP_001783719.1 CDS HSM_0370 NC_010519.1 413830 414441 R SMART: SH3 domain protein; KEGG: hso:HS_1192 hypothetical protein; SH3 domain-containing protein complement(413830..414441) Haemophilus somnus 2336 6108148 YP_001783720.1 CDS HSM_0371 NC_010519.1 414546 415808 R PFAM: phosphate transporter; KEGG: hso:HS_1191 phosphate permease; phosphate transporter complement(414546..415808) Haemophilus somnus 2336 6108150 YP_001783721.1 CDS HSM_0372 NC_010519.1 415835 416515 R PFAM: protein of unknown function DUF47; KEGG: hso:HS_1190 phosphate transport regulator; hypothetical protein complement(415835..416515) Haemophilus somnus 2336 6108151 YP_001783722.1 CDS HSM_0373 NC_010519.1 416658 417701 D PFAM: adenylate cyclase; KEGG: hso:HS_1189 hypothetical protein; adenylate cyclase 416658..417701 Haemophilus somnus 2336 6108152 YP_001783723.1 CDS HSM_0374 NC_010519.1 417711 419087 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 417711..419087 Haemophilus somnus 2336 6108153 YP_001783724.1 CDS HSM_0375 NC_010519.1 419189 419665 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid ABC transporterer; leucine-responsive transcriptional regulator 419189..419665 Haemophilus somnus 2336 6108154 YP_001783725.1 CDS HSM_0376 NC_010519.1 419667 422378 D PFAM: cell divisionFtsK/SpoIIIE; KEGG: hso:HS_1186 DNA translocase protein; cell division protein FtsK 419667..422378 Haemophilus somnus 2336 6108155 YP_001783726.1 CDS HSM_0377 NC_010519.1 422466 432413 R PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1616 large adhesin; YadA domain-containing protein complement(422466..432413) Haemophilus somnus 2336 6108156 YP_001783727.1 CDS HSM_0378 NC_010519.1 432942 433523 R PFAM: peptidylprolyl isomerase FKBP-type; KEGG: hso:HS_1631 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase); FKBP-type peptidylprolyl isomerase complement(432942..433523) Haemophilus somnus 2336 6108157 YP_001783728.1 CDS HSM_0379 NC_010519.1 433580 433993 R PFAM: protein of unknown function DUF1260; KEGG: hso:HS_1630 hypothetical protein; hypothetical protein complement(433580..433993) Haemophilus somnus 2336 6108158 YP_001783729.1 CDS HSM_0380 NC_010519.1 434010 434495 R TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: hso:HS_1629 tRNA/rRNA methyltransferase; RNA methyltransferase complement(434010..434495) Haemophilus somnus 2336 6108159 YP_001783730.1 CDS HSM_0381 NC_010519.1 434667 436283 R PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase complement(434667..436283) Haemophilus somnus 2336 6108161 YP_001783731.1 CDS glyA NC_010519.1 436463 437722 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(436463..437722) Haemophilus somnus 2336 6108162 YP_001783732.1 CDS HSM_0383 NC_010519.1 437865 439163 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(437865..439163) Haemophilus somnus 2336 6108163 YP_001783733.1 CDS HSM_0384 NC_010519.1 439160 440776 R PFAM: sulfatase; KEGG: pmu:PM0223 DcaA protein; sulfatase complement(439160..440776) Haemophilus somnus 2336 6108164 YP_001783734.1 CDS purH NC_010519.1 440792 442390 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(440792..442390) Haemophilus somnus 2336 6108165 YP_001783735.1 CDS HSM_0386 NC_010519.1 442525 443034 R PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: hso:HS_1624 SprT protein; hypothetical protein complement(442525..443034) Haemophilus somnus 2336 6108166 YP_001783736.1 CDS HSM_0387 NC_010519.1 443112 444266 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(443112..444266) Haemophilus somnus 2336 6108167 YP_001783737.1 CDS HSM_0388 NC_010519.1 444543 445121 D hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 444543..445121 Haemophilus somnus 2336 6108168 YP_001783738.1 CDS HSM_0389 NC_010519.1 445132 445926 D PFAM: protein of unknown function DUF81; KEGG: hso:HS_1621 permease; hypothetical protein 445132..445926 Haemophilus somnus 2336 6108169 YP_001783739.1 CDS HSM_0390 NC_010519.1 445936 446748 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 445936..446748 Haemophilus somnus 2336 6108170 YP_001783740.1 CDS thyA NC_010519.1 446755 447606 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 446755..447606 Haemophilus somnus 2336 6108172 YP_001783741.1 CDS HSM_0392 NC_010519.1 447628 448128 D PFAM: CMP/dCMP deaminase zinc-binding; KEGG: hso:HS_1618 hypothetical protein; CMP/dCMP deaminase 447628..448128 Haemophilus somnus 2336 6108173 YP_001783742.1 CDS HSM_0393 NC_010519.1 448099 450132 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-subunit beta is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(448099..450132) Haemophilus somnus 2336 6108174 YP_001783743.1 CDS HSM_0394 NC_010519.1 450581 460450 D PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1616 large adhesin; YadA domain-containing protein 450581..460450 Haemophilus somnus 2336 6108175 YP_001783744.1 CDS HSM_0395 NC_010519.1 460772 462007 D PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; tryptophan halogenase; KEGG: hso:HS_1615 dehydrogenase; tryptophan halogenase 460772..462007 Haemophilus somnus 2336 6108176 YP_001783745.1 CDS HSM_0396 NC_010519.1 462083 463690 D PFAM: protein of unknown function DUF195; KEGG: hso:HS_1614 DNA recombination protein RmuC; hypothetical protein 462083..463690 Haemophilus somnus 2336 6108177 YP_001783746.1 CDS rfaD NC_010519.1 463750 464679 D catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 463750..464679 Haemophilus somnus 2336 6108178 YP_001783747.1 CDS HSM_0398 NC_010519.1 464815 465855 D TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9; KEGG: hso:HS_1612 ADP-heptose--LPS heptosyltransferase II; lipopolysaccharide heptosyltransferase II 464815..465855 Haemophilus somnus 2336 6108179 YP_001783748.1 CDS HSM_0399 NC_010519.1 465857 466822 D TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: hso:HS_1611 lipopolysaccharide heptosyltransferase-1; ADP-heptose--LPS heptosyltransferase 465857..466822 Haemophilus somnus 2336 6108180 YP_001783749.1 CDS dapF NC_010519.1 466872 467696 R involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase complement(466872..467696) Haemophilus somnus 2336 6108181 YP_001783750.1 CDS HSM_0401 NC_010519.1 468014 468646 D KEGG: hso:HS_0337 hypothetical protein; hypothetical protein 468014..468646 Haemophilus somnus 2336 6108184 YP_001783751.1 CDS HSM_0402 NC_010519.1 468685 469182 R TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; KEGG: hso:HS_1609 molybdopterin-guanine dinucleotide biosynthesis protein B; molybdopterin-guanine dinucleotide biosynthesis protein B complement(468685..469182) Haemophilus somnus 2336 6108185 YP_001783752.1 CDS HSM_0403 NC_010519.1 469196 469630 R PFAM: Positive regulator of sigma(E) RseC/MucC; KEGG: hso:HS_1608 positive sigma-E factor regulatory protein; sigma E positive regulator RseC/MucC complement(469196..469630) Haemophilus somnus 2336 6108186 YP_001783753.1 CDS rseB NC_010519.1 469638 470576 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(469638..470576) Haemophilus somnus 2336 6108187 YP_001783754.1 CDS HSM_0405 NC_010519.1 470640 471224 R PFAM: anti sigma-E protein RseA family protein; anti sigma-E protein RseA domain protein; KEGG: hso:HS_1606 sigma-E factor negative regulatory protein; anti sigma-E protein RseA complement(470640..471224) Haemophilus somnus 2336 6108188 YP_001783755.1 CDS HSM_0406 NC_010519.1 471257 471832 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(471257..471832) Haemophilus somnus 2336 6108189 YP_001783756.1 CDS HSM_0407 NC_010519.1 471938 472192 R PFAM: protein of unknown function DUF339; KEGG: hso:HS_1604 hypothetical protein; hypothetical protein complement(471938..472192) Haemophilus somnus 2336 6108190 YP_001783757.1 CDS HSM_0408 NC_010519.1 472366 473007 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(472366..473007) Haemophilus somnus 2336 6108191 YP_001783758.1 CDS HSM_0409 NC_010519.1 473055 474458 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(473055..474458) Haemophilus somnus 2336 6108192 YP_001783759.1 CDS HSM_0410 NC_010519.1 474468 475883 R TIGRFAM: sugar (glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_1601 glucuronide permease; sugar (glycoside-Pentoside-hexuronide) transporter complement(474468..475883) Haemophilus somnus 2336 6108193 YP_001783760.1 CDS HSM_0411 NC_010519.1 475909 477669 R PFAM: glycoside hydrolase; KEGG: hso:HS_1600 beta-hexosamidase A, glycoside hydrolase family 3; glycoside hydrolase family protein complement(475909..477669) Haemophilus somnus 2336 6108195 YP_001783761.1 CDS HSM_0412 NC_010519.1 477711 478526 R KEGG: hso:HS_1599 hypothetical protein; hypothetical protein complement(477711..478526) Haemophilus somnus 2336 6108196 YP_001783762.1 CDS HSM_0413 NC_010519.1 478536 479381 R Converts D-mannonate to D-mannuronate; D-mannonate oxidoreductase complement(478536..479381) Haemophilus somnus 2336 6108197 YP_001783763.1 CDS HSM_0414 NC_010519.1 479631 480392 D PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: hso:HS_1597 uxu operon regulator; GntR family transcriptional regulator 479631..480392 Haemophilus somnus 2336 6108198 YP_001783764.1 CDS HSM_0415 NC_010519.1 480411 481595 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 480411..481595 Haemophilus somnus 2336 6108199 YP_001783765.1 CDS HSM_0416 NC_010519.1 481817 482344 R KEGG: hso:HS_1595 hypothetical protein; hypothetical protein complement(481817..482344) Haemophilus somnus 2336 6108200 YP_001783766.1 CDS HSM_0417 NC_010519.1 482505 483116 D HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 482505..483116 Haemophilus somnus 2336 6108201 YP_001783767.1 CDS HSM_0418 NC_010519.1 483140 484507 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 483140..484507 Haemophilus somnus 2336 6108202 YP_001783768.1 CDS HSM_0419 NC_010519.1 484587 485024 R KEGG: hso:HS_1592 acetyltransferase, GNAT family; GNAT family acetyltransferase complement(484587..485024) Haemophilus somnus 2336 6108203 YP_001783769.1 CDS tpiA NC_010519.1 485192 485959 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 485192..485959 Haemophilus somnus 2336 6108204 YP_001783770.1 CDS HSM_0421 NC_010519.1 486057 487337 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 486057..487337 Haemophilus somnus 2336 6108206 YP_001783771.1 CDS coaD NC_010519.1 487337 487813 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 487337..487813 Haemophilus somnus 2336 6108207 YP_001783772.1 CDS HSM_0423 NC_010519.1 487887 489725 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1588 ABC transporter permease/ATP-binding protein; ABC transporter 487887..489725 Haemophilus somnus 2336 6108208 YP_001783773.1 CDS HSM_0424 NC_010519.1 489808 490683 R PFAM: myo-inositol catabolism IolB domain protein; KEGG: hso:HS_1587 conserved hypothetical protein; myo-inositol catabolism IolB domain-containing protein complement(489808..490683) Haemophilus somnus 2336 6108209 YP_001783774.1 CDS HSM_0425 NC_010519.1 490875 492260 D PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_1586 permease, MFS superfamily; major facilitator transporter 490875..492260 Haemophilus somnus 2336 6108210 YP_001783775.1 CDS HSM_0426 NC_010519.1 492271 493119 D KEGG: hso:HS_1585 hypothetical protein; hypothetical protein 492271..493119 Haemophilus somnus 2336 6108211 YP_001783776.1 CDS HSM_0427 NC_010519.1 493280 494788 D TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: hso:HS_1584 NAD-dependent aldehyde dehydrogenase; methylmalonate-semialdehyde dehydrogenase 493280..494788 Haemophilus somnus 2336 6108212 YP_001783777.1 CDS HSM_0428 NC_010519.1 494872 496008 D PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: hso:HS_1583 dehydrogenase; oxidoreductase domain-containing protein 494872..496008 Haemophilus somnus 2336 6108213 YP_001783778.1 CDS HSM_0429 NC_010519.1 496303 497238 D PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_1582 ABC transporter periplasmic sugar-binding protein; monosaccharide-transporting ATPase 496303..497238 Haemophilus somnus 2336 6108214 YP_001783779.1 CDS HSM_0430 NC_010519.1 497325 498260 D PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_1581 ABC transporter periplasmic sugar-binding protein; monosaccharide-transporting ATPase 497325..498260 Haemophilus somnus 2336 6108215 YP_001783780.1 CDS HSM_0431 NC_010519.1 498341 499858 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1580 sugar ABC transporter ATP-binding protein; ABC transporter 498341..499858 Haemophilus somnus 2336 6108217 YP_001783781.1 CDS HSM_0432 NC_010519.1 499896 500852 D PFAM: inner-membrane translocator; KEGG: hso:HS_1579 ABC transporter ribose permease; monosaccharide-transporting ATPase 499896..500852 Haemophilus somnus 2336 6108218 YP_001783782.1 CDS HSM_0433 NC_010519.1 501039 502976 D PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: hso:HS_1578 myo-inositol catabolism protein; thiamine pyrophosphate protein central region 501039..502976 Haemophilus somnus 2336 6108219 YP_001783783.1 CDS HSM_0434 NC_010519.1 503050 503946 D PFAM: xylose isomerase; KEGG: hso:HS_1577 myo-inositol catabolism protein; xylose isomerase 503050..503946 Haemophilus somnus 2336 6108220 YP_001783784.1 CDS HSM_0435 NC_010519.1 503948 504958 D PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: hso:HS_1576 dehydrogenase; inositol 2-dehydrogenase 503948..504958 Haemophilus somnus 2336 6108221 YP_001783785.2 CDS HSM_0436 NC_010519.1 505019 505756 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE complement(505019..505756) Haemophilus somnus 2336 6108222 YP_001783786.1 CDS potE NC_010519.1 505874 507184 R catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter complement(505874..507184) Haemophilus somnus 2336 6108223 YP_001783787.1 CDS HSM_0438 NC_010519.1 507242 509401 R PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: hso:HS_1573 ornithine decarboxylase; ornithine decarboxylase complement(507242..509401) Haemophilus somnus 2336 6108224 YP_001783788.1 CDS HSM_0439 NC_010519.1 509682 509846 R KEGG: pmu:PM0805 unknown; hypothetical protein complement(509682..509846) Haemophilus somnus 2336 6108225 YP_001783789.1 CDS HSM_0440 NC_010519.1 510013 510345 R PFAM: SirA family protein; KEGG: hso:HS_1572 hypothetical protein; SirA family protein complement(510013..510345) Haemophilus somnus 2336 6108226 YP_001783790.1 CDS HSM_0441 NC_010519.1 510325 510933 D PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: hso:HS_1571 hypothetical protein; hypothetical protein 510325..510933 Haemophilus somnus 2336 6108228 YP_001783791.1 CDS HSM_0442 NC_010519.1 510945 512408 D TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: hso:HS_1570 potassium uptake system protein; TrkH family potassium uptake protein 510945..512408 Haemophilus somnus 2336 6108229 YP_001783792.1 CDS hemG NC_010519.1 512408 512920 D catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 512408..512920 Haemophilus somnus 2336 6108230 YP_001783793.1 CDS HSM_0445 NC_010519.1 519037 519393 D KEGG: bce:BC4488 hypothetical protein; hypothetical protein 519037..519393 Haemophilus somnus 2336 6108855 YP_001783794.1 CDS HSM_0446 NC_010519.1 519568 522381 D KEGG: cps:CPS_2955 hypothetical protein; exonuclease V subunit alpha 519568..522381 Haemophilus somnus 2336 6108232 YP_001783795.1 CDS HSM_0447 NC_010519.1 522375 522641 D hypothetical protein 522375..522641 Haemophilus somnus 2336 6108233 YP_001783796.1 CDS HSM_0450 NC_010519.1 524912 525670 R catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase complement(524912..525670) Haemophilus somnus 2336 6108235 YP_001783797.1 CDS HSM_0451 NC_010519.1 525954 526772 D KEGG: hso:HS_1518 hypothetical protein; hypothetical protein 525954..526772 Haemophilus somnus 2336 6108237 YP_001783798.1 CDS HSM_0452 NC_010519.1 526787 527095 R PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIsubunit alpha; KEGG: vfi:VF0607 PTS system, diacetylchitobiose-specific IIA component; PTS system lactose/cellobiose-specific transporter subunit IIA complement(526787..527095) Haemophilus somnus 2336 6108238 YP_001783799.1 CDS HSM_0453 NC_010519.1 527092 527403 R PFAM: phosphotransferase system lactose/cellobiose-specific IIsubunit beta; KEGG: vfi:VF0604 PTS system, cellobiose-specific IIB component; PTS system lactose/cellobiose-specific transporter subunit IIB complement(527092..527403) Haemophilus somnus 2336 6108239 YP_001783800.1 CDS HSM_0454 NC_010519.1 527413 528858 R PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: rma:Rmag_0211 leucyl aminopeptidase; leucyl aminopeptidase complement(527413..528858) Haemophilus somnus 2336 6108240 YP_001783801.1 CDS HSM_0455 NC_010519.1 528855 529817 R PFAM: peptidase T2 asparaginase 2; KEGG: lga:LGAS_1433 asparaginase; asparaginase complement(528855..529817) Haemophilus somnus 2336 6108241 YP_001783802.1 CDS HSM_0456 NC_010519.1 529818 531092 R TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PTS system, cellobiose-specific IIC subunit; PFAM: phosphotransferase system EIIC; KEGG: bsu:BG10562 PTS cellobiose-specific enzyme IIC component; PTS system lactose/cellobiose family transporter subunit IIC complement(529818..531092) Haemophilus somnus 2336 6108242 YP_001783803.1 CDS HSM_0457 NC_010519.1 531276 532007 D PFAM: CutC family protein; KEGG: hso:HS_1517 copper homeostasis protein; CutC family protein 531276..532007 Haemophilus somnus 2336 6108243 YP_001783804.1 CDS HSM_0458 NC_010519.1 532182 535082 D transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 532182..535082 Haemophilus somnus 2336 6108244 YP_001783805.1 CDS HSM_0459 NC_010519.1 535084 535749 D PFAM: pseudouridine synthase; KEGG: hso:HS_1515 ribosomal large subunit pseudouridine synthase A; pseudouridine synthase 535084..535749 Haemophilus somnus 2336 6108245 YP_001783806.1 CDS HSM_0460 NC_010519.1 535812 536576 R PFAM: peptidase M48 Ste24p; KEGG: hso:HS_1514 hypothetical protein; peptidase M48 Ste24p complement(535812..536576) Haemophilus somnus 2336 6108246 YP_001783807.1 CDS HSM_0461 NC_010519.1 536635 537162 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(536635..537162) Haemophilus somnus 2336 6108248 YP_001783808.1 CDS HSM_0462 NC_010519.1 537334 538584 D TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; KEGG: hso:HS_1562 tryptophan-specific transporter; aromatic amino acid transporter 537334..538584 Haemophilus somnus 2336 6108249 YP_001783809.1 CDS HSM_0463 NC_010519.1 538744 539286 D regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 538744..539286 Haemophilus somnus 2336 6108250 YP_001783810.1 CDS HSM_0464 NC_010519.1 539348 540313 D PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: hso:HS_1560 peptidyl-prolyl cis-trans isomerase, PPIC-type; PpiC-type peptidyl-prolyl cis-trans isomerase 539348..540313 Haemophilus somnus 2336 6108251 YP_001783811.1 CDS ksgA NC_010519.1 540389 541234 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 540389..541234 Haemophilus somnus 2336 6108252 YP_001783812.1 CDS apaH NC_010519.1 541285 542106 D hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 541285..542106 Haemophilus somnus 2336 6108253 YP_001783813.1 CDS leuS NC_010519.1 542393 544975 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 542393..544975 Haemophilus somnus 2336 6108254 YP_001783814.1 CDS HSM_0468 NC_010519.1 545024 545527 D PFAM: Rare lipoprotein B; KEGG: hso:HS_1556 conserved hypothetical protein; rare lipoprotein B 545024..545527 Haemophilus somnus 2336 6108255 YP_001783815.1 CDS holA NC_010519.1 545527 546567 D required for the assembly and function of the DNAX complex which is required for the assembly of the subunit beta onto primed DNA; DNA polymerase III subunit delta 545527..546567 Haemophilus somnus 2336 6108256 YP_001783816.1 CDS HSM_0470 NC_010519.1 546694 547344 D TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: ATPase AAA; KEGG: hso:HS_1554 cell-division ATP-binding protein; cell division ATP-binding protein FtsE 546694..547344 Haemophilus somnus 2336 6108257 YP_001783817.1 CDS ftsX NC_010519.1 547354 548292 D ABC transporter membrane protein; cell division protein FtsX 547354..548292 Haemophilus somnus 2336 6108259 YP_001783818.1 CDS HSM_0472 NC_010519.1 548419 549534 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 548419..549534 Haemophilus somnus 2336 6108260 YP_001783819.1 CDS HSM_0473 NC_010519.1 549727 550764 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(549727..550764) Haemophilus somnus 2336 6108261 YP_001783820.1 CDS HSM_0474 NC_010519.1 550953 551627 R MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein complement(550953..551627) Haemophilus somnus 2336 6108262 YP_001783821.1 CDS HSM_0475 NC_010519.1 551624 552166 R TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: hso:HS_1549 methylated-DNA-protein-cysteine methyltransferase; methylated-DNA--protein-cysteine methyltransferase complement(551624..552166) Haemophilus somnus 2336 6108263 YP_001783822.1 CDS HSM_0476 NC_010519.1 552218 553408 R PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: hso:HS_1548 outer membrane protein P1; aromatic hydrocarbon degradation membrane protein complement(552218..553408) Haemophilus somnus 2336 6108264 YP_001783823.1 CDS HSM_0477 NC_010519.1 553398 553649 R KEGG: hso:HS_1548 outer membrane protein P1; outer membrane protein P1 complement(553398..553649) Haemophilus somnus 2336 6108265 YP_001783824.1 CDS HSM_0478 NC_010519.1 553890 554186 D PFAM: conserved hypothetical protein 743; KEGG: hso:HS_1547 hypothetical protein; hypothetical protein 553890..554186 Haemophilus somnus 2336 6108266 YP_001783825.1 CDS HSM_0479 NC_010519.1 554339 555028 D PFAM: pirin; Cupin 2 conserved barrel domain protein; KEGG: hso:HS_1546 conserved hypothetical protein; pirin domain-containing protein 554339..555028 Haemophilus somnus 2336 6108267 YP_001783826.1 CDS HSM_0480 NC_010519.1 555136 555978 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(555136..555978) Haemophilus somnus 2336 6108268 YP_001783827.1 CDS HSM_0481 NC_010519.1 556101 556415 R KEGG: hso:HS_1544 hypothetical protein; hypothetical protein complement(556101..556415) Haemophilus somnus 2336 6108270 YP_001783828.1 CDS murB NC_010519.1 556431 557456 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(556431..557456) Haemophilus somnus 2336 6108271 YP_001783829.1 CDS HSM_0483 NC_010519.1 557466 559244 R PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: hso:HS_1510 nitrate/nitrite sensor protein; nitrate/nitrite sensor protein NarQ complement(557466..559244) Haemophilus somnus 2336 6108272 YP_001783830.1 CDS HSM_0484 NC_010519.1 559358 562198 D PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases; KEGG: dvl:Dvul_0853 type III restriction enzyme, res subunit; type III restriction protein res subunit 559358..562198 Haemophilus somnus 2336 6108273 YP_001783831.1 CDS HSM_0485 NC_010519.1 562219 563214 D KEGG: hit:NTHI0317 conserved hypothetical DNA binding protein; DNA binding protein 562219..563214 Haemophilus somnus 2336 6108274 YP_001783832.1 CDS HSM_0486 NC_010519.1 563222 564637 D PFAM: restriction modification system DNA specificity domain; KEGG: mbu:Mbur_0508 restriction modification system DNA specificity subunit; restriction modification system DNA specificity subunit 563222..564637 Haemophilus somnus 2336 6108275 YP_001783833.1 CDS HSM_0487 NC_010519.1 564631 564834 D hypothetical protein 564631..564834 Haemophilus somnus 2336 6108276 YP_001783834.1 CDS HSM_0488 NC_010519.1 564878 565087 D hypothetical protein 564878..565087 Haemophilus somnus 2336 6108277 YP_001783835.1 CDS HSM_0489 NC_010519.1 565134 566492 D KEGG: gka:GK0575 hypothetical protein; transcriptional regulator 565134..566492 Haemophilus somnus 2336 6108278 YP_001783836.1 CDS HSM_0492 NC_010519.1 568291 568572 D PFAM: NapD family protein; KEGG: hso:HS_1509 periplasmic nitrate reductase, component NapD; NapD family protein 568291..568572 Haemophilus somnus 2336 6108281 YP_001783837.1 CDS HSM_0493 NC_010519.1 568599 571082 D periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 568599..571082 Haemophilus somnus 2336 6108282 YP_001783838.1 CDS napG NC_010519.1 571133 571885 D part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 571133..571885 Haemophilus somnus 2336 6108283 YP_001783839.1 CDS napH NC_010519.1 571885 572757 D part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 571885..572757 Haemophilus somnus 2336 6108284 YP_001783840.1 CDS HSM_0496 NC_010519.1 572754 573179 D PFAM: nitrate reductase cytochrome C subunit (NapB); KEGG: hso:HS_1505 periplasmic nitrate reductase; nitrate reductase cytochrome c-type subunit NapB 572754..573179 Haemophilus somnus 2336 6108285 YP_001783841.1 CDS HSM_0497 NC_010519.1 573194 573805 D PFAM: NapC/NirT cytochrome C domain protein; KEGG: hso:HS_1504 cytochrome C protein; NapC/NirT cytochrome C domain-containing protein 573194..573805 Haemophilus somnus 2336 6108286 YP_001783842.1 CDS HSM_0498 NC_010519.1 573900 577793 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(573900..577793) Haemophilus somnus 2336 6108287 YP_001783843.1 CDS HSM_0499 NC_010519.1 577974 579011 R PFAM: peptidoglycan-binding LysM; peptidase M23B; KEGG: hso:HS_1502 lipoprotein B; peptidase M23B complement(577974..579011) Haemophilus somnus 2336 6108288 YP_001783844.1 CDS HSM_0500 NC_010519.1 579052 579627 R PFAM: SNARE associated Golgi protein; KEGG: hso:HS_1501 lipoprotein B; hypothetical protein complement(579052..579627) Haemophilus somnus 2336 6108289 YP_001783845.1 CDS surE NC_010519.1 579657 580397 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(579657..580397) Haemophilus somnus 2336 6108292 YP_001783846.1 CDS truD NC_010519.1 580421 581428 R catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D complement(580421..581428) Haemophilus somnus 2336 6108293 YP_001783847.1 CDS ispF NC_010519.1 581428 581916 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(581428..581916) Haemophilus somnus 2336 6108294 YP_001783848.1 CDS HSM_0504 NC_010519.1 581929 583734 R TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: hso:HS_1497 glutathione-regulated potassium-efflux system protein; potassium efflux system protein complement(581929..583734) Haemophilus somnus 2336 6108295 YP_001783849.1 CDS ispD NC_010519.1 583740 584423 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(583740..584423) Haemophilus somnus 2336 6108296 YP_001783850.1 CDS ftsB NC_010519.1 584424 584705 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(584424..584705) Haemophilus somnus 2336 6108297 YP_001783851.1 CDS greB NC_010519.1 584715 585191 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB complement(584715..585191) Haemophilus somnus 2336 6108298 YP_001783852.1 CDS HSM_0508 NC_010519.1 585371 587674 D PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: hso:HS_1493 transcription accessory protein, RNA-binding protein containing S1 domain; RNA-binding S1 domain-containing protein 585371..587674 Haemophilus somnus 2336 6108299 YP_001783853.1 CDS HSM_0509 NC_010519.1 587741 589057 D PFAM: branched-chain amino acid ABC transporterer II carrier protein; KEGG: hso:HS_1492 branched-chain amino acid carrier protein; branched-chain amino acid ABC transporterer II carrier protein 587741..589057 Haemophilus somnus 2336 6108300 YP_001783854.1 CDS HSM_0510 NC_010519.1 589095 589676 R cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein complement(589095..589676) Haemophilus somnus 2336 6108301 YP_001783855.1 CDS HSM_0511 NC_010519.1 589769 590467 R KEGG: hso:HS_1490 competence protein; competence protein complement(589769..590467) Haemophilus somnus 2336 6108303 YP_001783856.1 CDS HSM_0512 NC_010519.1 590614 591426 D TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: hso:HS_1489 Cof protein; cof family hydrolase 590614..591426 Haemophilus somnus 2336 6108304 YP_001783857.1 CDS HSM_0513 NC_010519.1 591558 592598 D PFAM: aminodeoxychorismate lyase; KEGG: hso:HS_1488 hypothetical protein; aminodeoxychorismate lyase 591558..592598 Haemophilus somnus 2336 6108305 YP_001783858.1 CDS tmk NC_010519.1 592608 593240 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 592608..593240 Haemophilus somnus 2336 6108306 YP_001783859.1 CDS HSM_0515 NC_010519.1 593164 594222 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the subunit beta on the DNA; DNA polymerase III subunit delta' 593164..594222 Haemophilus somnus 2336 6108307 YP_001783860.1 CDS HSM_0516 NC_010519.1 594231 595013 D TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: hso:HS_1485 conserved hypothetical protein; TatD family hydrolase 594231..595013 Haemophilus somnus 2336 6108308 YP_001783861.1 CDS HSM_0517 NC_010519.1 595041 595568 D PFAM: protein of unknown function DUF1523; KEGG: hso:HS_1484 hypothetical protein; hypothetical protein 595041..595568 Haemophilus somnus 2336 6108309 YP_001783862.1 CDS HSM_0518 NC_010519.1 595629 596918 D PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: hso:HS_1483 hypothetical protein; hypothetical protein 595629..596918 Haemophilus somnus 2336 6108310 YP_001783863.1 CDS HSM_0519 NC_010519.1 597062 597505 R KEGG: hso:HS_1482 hypothetical protein; hypothetical protein complement(597062..597505) Haemophilus somnus 2336 6108311 YP_001783864.1 CDS HSM_0520 NC_010519.1 597527 598132 R KEGG: hso:HS_1481 hypothetical protein; hypothetical protein complement(597527..598132) Haemophilus somnus 2336 6108312 YP_001783865.1 CDS HSM_0521 NC_010519.1 598461 599030 R PFAM: GPR1/FUN34/yaaH family protein; KEGG: hso:HS_1480 conserved hypothetical protein; GPR1/FUN34/yaaH family protein complement(598461..599030) Haemophilus somnus 2336 6108314 YP_001783866.1 CDS HSM_0522 NC_010519.1 599470 600672 D Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 599470..600672 Haemophilus somnus 2336 6108315 YP_001783867.1 CDS HSM_0523 NC_010519.1 600682 600912 D KEGG: hso:HS_1478 hypothetical protein; hypothetical protein 600682..600912 Haemophilus somnus 2336 6108316 YP_001783868.1 CDS lysS NC_010519.1 600962 602470 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(600962..602470) Haemophilus somnus 2336 6108317 YP_001783869.1 CDS HSM_0525 NC_010519.1 602547 603416 R TIGRFAM: peptide chain release factor 2; PFAM: class I peptide chain release factor; PCRF domain protein; KEGG: msu:MS1542 protein chain release factor B; peptide chain release factor 2 complement(602547..603416) Haemophilus somnus 2336 6108318 YP_001783870.1 CDS HSM_0526 NC_010519.1 603776 604471 D KEGG: hso:HS_1475 thiol:disulfide interchange protein; thiol:disulfide interchange protein 603776..604471 Haemophilus somnus 2336 6108319 YP_001783871.1 CDS HSM_0527 NC_010519.1 604464 606185 D TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: hso:HS_1474 single-strand DNA-specific exonuclease; single-stranded-DNA-specific exonuclease RecJ 604464..606185 Haemophilus somnus 2336 6108320 YP_001783872.1 CDS HSM_0528 NC_010519.1 606234 606383 D KEGG: hit:NTHI1387 hypothetical protein; hypothetical protein 606234..606383 Haemophilus somnus 2336 6108321 YP_001783873.1 CDS HSM_0529 NC_010519.1 606380 607069 D enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 606380..607069 Haemophilus somnus 2336 6108322 YP_001783874.1 CDS HSM_0530 NC_010519.1 607181 607300 D KEGG: hin:HI1720 hypothetical protein; hypothetical protein 607181..607300 Haemophilus somnus 2336 6108323 YP_001783875.1 CDS HSM_0531 NC_010519.1 607402 607560 D KEGG: hin:HI1721 transposase; transposase 607402..607560 Haemophilus somnus 2336 6108325 YP_001783876.1 CDS HSM_0532 NC_010519.1 607593 607736 D KEGG: hin:HI1721 transposase; transposase 607593..607736 Haemophilus somnus 2336 6108326 YP_001783877.1 CDS HSM_0533 NC_010519.1 607788 608000 R PFAM: ribosomal protein L31; KEGG: hso:HS_1472 50S ribosomal protein L31; 50S ribosomal protein L31 complement(607788..608000) Haemophilus somnus 2336 6108327 YP_001783878.1 CDS HSM_0534 NC_010519.1 608194 609852 R TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein; KEGG: hso:HS_1470 conserved hypothetical protein; hypothetical protein complement(608194..609852) Haemophilus somnus 2336 6108328 YP_001783879.1 CDS HSM_0537 NC_010519.1 612131 614257 D Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 612131..614257 Haemophilus somnus 2336 6108330 YP_001783880.1 CDS nrdG NC_010519.1 614273 614740 D activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 614273..614740 Haemophilus somnus 2336 6108331 YP_001783881.1 CDS HSM_0539 NC_010519.1 615013 616740 R PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron maturase-specific domain protein; SMART: HNH nuclease; KEGG: pau:PA14_07480 reverse transcriptase; RNA-directed DNA polymerase complement(615013..616740) Haemophilus somnus 2336 6108332 YP_001783882.1 CDS HSM_0540 NC_010519.1 618335 619339 R TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: hso:HS_1466 glyceraldehyde 3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase complement(618335..619339) Haemophilus somnus 2336 6108333 YP_001783883.1 CDS HSM_0541 NC_010519.1 619572 619721 R KEGG: hso:HS_1465 hypothetical protein; hypothetical protein complement(619572..619721) Haemophilus somnus 2336 6108335 YP_001783884.1 CDS HSM_0542 NC_010519.1 619796 620599 D PFAM: Choline/ethanolamine kinase; KEGG: hso:HS_1461 LicA protein; choline/ethanolamine kinase 619796..620599 Haemophilus somnus 2336 6108336 YP_001783885.1 CDS HSM_0543 NC_010519.1 620586 621518 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: hso:HS_1460 lic-1 operon protein (LicB); hypothetical protein 620586..621518 Haemophilus somnus 2336 6108337 YP_001783886.1 CDS HSM_0544 NC_010519.1 621515 622213 D KEGG: hso:HS_1459 LicC protein; LicC protein 621515..622213 Haemophilus somnus 2336 6108338 YP_001783887.1 CDS HSM_0545 NC_010519.1 622215 623015 D PFAM: LicD family protein; KEGG: hso:HS_1458 lipopolysaccharide choline phosphotransferase; LicD family protein 622215..623015 Haemophilus somnus 2336 6108339 YP_001783888.1 CDS gmk NC_010519.1 623124 623750 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 623124..623750 Haemophilus somnus 2336 6108340 YP_001783889.1 CDS rpoZ NC_010519.1 623805 624077 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and subunit alphas; DNA-directed RNA polymerase subunit omega 623805..624077 Haemophilus somnus 2336 6108341 YP_001783890.1 CDS HSM_0548 NC_010519.1 624158 626281 D KEGG: hso:HS_1455 guanosine-3'5'-bis(diphosphate) 3'-pyrophosphohydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region; (p)ppGpp synthetase I SpoT/RelA 624158..626281 Haemophilus somnus 2336 6108342 YP_001783891.1 CDS HSM_0549 NC_010519.1 626281 628362 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 626281..628362 Haemophilus somnus 2336 6108343 YP_001783892.1 CDS HSM_0550 NC_010519.1 628432 629235 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 628432..629235 Haemophilus somnus 2336 6108344 YP_001783893.1 CDS HSM_0551 NC_010519.1 635838 636359 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: hso:HS_1567 permease, drug/metabolite transporter superfamily; hypothetical protein 635838..636359 Haemophilus somnus 2336 6108863 YP_001783894.1 CDS HSM_0552 NC_010519.1 636597 637931 D functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 636597..637931 Haemophilus somnus 2336 6108347 YP_001783895.1 CDS rpoB NC_010519.1 638435 642463 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; subunit beta is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 638435..642463 Haemophilus somnus 2336 6108348 YP_001783896.1 CDS HSM_0554 NC_010519.1 642554 646816 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 642554..646816 Haemophilus somnus 2336 6108349 YP_001783897.1 CDS HSM_0555 NC_010519.1 647153 648004 D involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR 647153..648004 Haemophilus somnus 2336 6108350 YP_001783898.1 CDS HSM_0556 NC_010519.1 648199 649134 D PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ecj:JW4049 D-allose transporter subunit; D-allose transporter subunit 648199..649134 Haemophilus somnus 2336 6108351 YP_001783899.1 CDS HSM_0557 NC_010519.1 649182 650717 D with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein 649182..650717 Haemophilus somnus 2336 6108352 YP_001783900.1 CDS HSM_0558 NC_010519.1 650717 651667 D PFAM: inner-membrane translocator; KEGG: ecc:c5092 D-allose transporter permease alsC; D-allose transporter subunit 650717..651667 Haemophilus somnus 2336 6108353 YP_001783901.1 CDS HSM_0559 NC_010519.1 651685 652371 D PFAM: ribulose-phosphate 3-epimerase; KEGG: ecj:JW4046 allulose-6-phosphate 3-epimerase; allulose-6-phosphate 3-epimerase 651685..652371 Haemophilus somnus 2336 6108354 YP_001783902.1 CDS HSM_0560 NC_010519.1 652371 653261 D PFAM: ROK family protein; KEGG: ecp:ECP_4326 D-allose kinase; D-allose kinase 652371..653261 Haemophilus somnus 2336 6108355 YP_001783903.1 CDS HSM_0561 NC_010519.1 653261 653734 D TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: ribose/galactose isomerase; KEGG: llc:LACR_1638 galactose 6-phosphate isomerase; RpiB/LacA/LacB family sugar-phosphate isomerase 653261..653734 Haemophilus somnus 2336 6108357 YP_001783904.1 CDS hslU NC_010519.1 654233 655564 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(654233..655564) Haemophilus somnus 2336 6108358 YP_001783905.1 CDS HSM_0563 NC_010519.1 655582 656109 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(655582..656109) Haemophilus somnus 2336 6108359 YP_001783906.1 CDS hemE NC_010519.1 656396 657460 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 656396..657460 Haemophilus somnus 2336 6108360 YP_001783907.1 CDS HSM_0565 NC_010519.1 657477 658067 D PFAM: protein of unknown function DUF416; KEGG: hso:HS_1539 hypothetical protein; hypothetical protein 657477..658067 Haemophilus somnus 2336 6108361 YP_001783908.1 CDS HSM_0566 NC_010519.1 658226 658501 D PFAM: histone family protein DNA-binding protein; KEGG: hso:HS_1538 DNA-binding protein HU; histone family protein DNA-binding protein 658226..658501 Haemophilus somnus 2336 6108362 YP_001783909.1 CDS HSM_0567 NC_010519.1 658663 659445 D PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: hso:HS_1537 transcriptional regulator, DeoR family; DeoR family transcriptional regulator 658663..659445 Haemophilus somnus 2336 6108363 YP_001783910.1 CDS HSM_0568 NC_010519.1 659471 661303 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 659471..661303 Haemophilus somnus 2336 6108364 YP_001783911.1 CDS HSM_0569 NC_010519.1 661375 662205 R TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: hso:HS_1535 outer membrane lipoprotein 1 precursor; YaeC family lipoprotein complement(661375..662205) Haemophilus somnus 2336 6108365 YP_001783912.1 CDS HSM_0570 NC_010519.1 662241 662930 R PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_1534 D-methionine ABC transporter permease; binding-protein-dependent transporters inner membrane component complement(662241..662930) Haemophilus somnus 2336 6108366 YP_001783913.1 CDS metN NC_010519.1 662920 663957 R part of the metNIQ transporter for methionine; DL-methionine transporter ATP-binding subunit complement(662920..663957) Haemophilus somnus 2336 6108368 YP_001783914.1 CDS HSM_0572 NC_010519.1 664112 664666 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 664112..664666 Haemophilus somnus 2336 6108369 YP_001783915.1 CDS HSM_0573 NC_010519.1 664818 665894 R PFAM: protein of unknown function DUF1603; KEGG: hpy:HP1471 type IIS restriction enzyme R protein; hypothetical protein complement(664818..665894) Haemophilus somnus 2336 6108370 YP_001783916.1 CDS HSM_0576 NC_010519.1 668254 669396 R PFAM: glycerate kinase; KEGG: hso:HS_1524 glycerate kinase; glycerate kinase complement(668254..669396) Haemophilus somnus 2336 6108372 YP_001783917.1 CDS HSM_0577 NC_010519.1 669422 670681 R PFAM: gluconate transporter; citrate transporter; KEGG: hit:NTHI0171 hypothetical protein; citrate transporter complement(669422..670681) Haemophilus somnus 2336 6108373 YP_001783918.1 CDS HSM_0578 NC_010519.1 670809 671927 R PFAM: sugar diacid recognition domain protein; KEGG: hso:HS_1521 sugar diacid utilization regulator; CdaR family transcriptional regulator complement(670809..671927) Haemophilus somnus 2336 6108374 YP_001783919.1 CDS HSM_0579 NC_010519.1 677604 677888 R KEGG: hso:HS_1452 hypothetical protein; hypothetical protein complement(677604..677888) Haemophilus somnus 2336 6108867 YP_001783920.1 CDS HSM_0580 NC_010519.1 678110 678757 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(678110..678757) Haemophilus somnus 2336 6108376 YP_001783921.1 CDS HSM_0581 NC_010519.1 678771 679205 R PFAM: RbsD or FucU transport; KEGG: hso:HS_1450 fucose operon FucU protein; transport protein RbsD/FucU complement(678771..679205) Haemophilus somnus 2336 6108378 YP_001783922.1 CDS HSM_0582 NC_010519.1 679199 680656 R TIGRFAM: L-fuculokinase; PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_1449 L-fuculokinase; L-fuculokinase complement(679199..680656) Haemophilus somnus 2336 6108379 YP_001783923.1 CDS fucI NC_010519.1 680738 682504 R catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase complement(680738..682504) Haemophilus somnus 2336 6108380 YP_001783924.1 CDS HSM_0584 NC_010519.1 682700 683995 R TIGRFAM: L-fucose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_1447 L-fucose permease; L-fucose transporter complement(682700..683995) Haemophilus somnus 2336 6108381 YP_001783925.1 CDS HSM_0585 NC_010519.1 684250 685002 R PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: hso:HS_1446 L-fucose operon activator; DeoR family transcriptional regulator complement(684250..685002) Haemophilus somnus 2336 6108382 YP_001783926.1 CDS gpmA NC_010519.1 685238 685921 D 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 685238..685921 Haemophilus somnus 2336 6108383 YP_001783927.1 CDS rimO NC_010519.1 686061 687392 D catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; 30S ribosomal protein S12 methylthiotransferase 686061..687392 Haemophilus somnus 2336 6108384 YP_001783928.1 CDS HSM_0588 NC_010519.1 687484 688716 D PFAM: peptidase M23B; KEGG: hso:HS_1443 hypothetical protein; peptidase M23B 687484..688716 Haemophilus somnus 2336 6108385 YP_001783929.1 CDS HSM_0589 NC_010519.1 688718 689575 D PFAM: protein of unknown function DUF610 YibQ; KEGG: hso:HS_1442 hypothetical protein; hypothetical protein 688718..689575 Haemophilus somnus 2336 6108386 YP_001783930.1 CDS HSM_0590 NC_010519.1 689630 690082 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(689630..690082) Haemophilus somnus 2336 6108387 YP_001783931.1 CDS HSM_0591 NC_010519.1 690266 691258 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 690266..691258 Haemophilus somnus 2336 6108389 YP_001783932.1 CDS HSM_0592 NC_010519.1 691375 692097 D PFAM: MgtC/SapB transporter; KEGG: hso:HS_1439 conserved hypothetical protein; MgtC/SapB transporter 691375..692097 Haemophilus somnus 2336 6108390 YP_001783933.1 CDS HSM_0593 NC_010519.1 692750 693163 R hypothetical protein complement(692750..693163) Haemophilus somnus 2336 6108391 YP_001783934.1 CDS HSM_0594 NC_010519.1 693192 694253 R KEGG: hdu:HD1616 transposase; transposase complement(693192..694253) Haemophilus somnus 2336 6108392 YP_001783935.1 CDS HSM_0595 NC_010519.1 694739 695035 R KEGG: ngo:NGO0366 hypothetical protein; hypothetical protein complement(694739..695035) Haemophilus somnus 2336 6108393 YP_001783936.1 CDS HSM_0596 NC_010519.1 695021 696139 D TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: ngo:NGO0365 site-specific DNA-methyltransferase M.NgoVII; DNA-cytosine methyltransferase 695021..696139 Haemophilus somnus 2336 6108394 YP_001783937.1 CDS HSM_0597 NC_010519.1 696139 697188 D KEGG: ngo:NGO0364 restriction endonuclease R.NgoVII; type II site-specific deoxyribonuclease 696139..697188 Haemophilus somnus 2336 6108395 YP_001783938.1 CDS HSM_0598 NC_010519.1 697189 699078 D KEGG: ngo:NGO0363 stress-sensitive restriction system protein; stress-sensitive restriction system protein 697189..699078 Haemophilus somnus 2336 6108396 YP_001783939.1 CDS HSM_0599 NC_010519.1 699183 699461 R PFAM: helix-turn-helix domain protein; KEGG: hdu:HD1613 hypothetical protein; XRE family transcriptional regulator complement(699183..699461) Haemophilus somnus 2336 6108397 YP_001783940.1 CDS HSM_0602 NC_010519.1 700602 701042 D KEGG: hdu:HD1697 hypothetical protein; hypothetical protein 700602..701042 Haemophilus somnus 2336 6108401 YP_001783941.1 CDS HSM_0603 NC_010519.1 701055 701204 R hypothetical protein complement(701055..701204) Haemophilus somnus 2336 6108402 YP_001783942.1 CDS rpsF NC_010519.1 701737 702114 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 701737..702114 Haemophilus somnus 2336 6108403 YP_001783943.1 CDS HSM_0605 NC_010519.1 702101 702427 D binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 702101..702427 Haemophilus somnus 2336 6108404 YP_001783944.1 CDS rpsR NC_010519.1 702440 702667 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 702440..702667 Haemophilus somnus 2336 6108405 YP_001783945.1 CDS rplI NC_010519.1 702686 703135 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 702686..703135 Haemophilus somnus 2336 6108406 YP_001783946.1 CDS HSM_0608 NC_010519.1 703668 704855 D TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: hso:HS_1434 N-acyl-L-amino acid amidohydrolase; amidohydrolase 703668..704855 Haemophilus somnus 2336 6108407 YP_001783947.1 CDS HSM_0609 NC_010519.1 705119 706027 D PFAM: protein of unknown function DUF511; KEGG: pin:Ping_0238 hypothetical protein DUF511; hypothetical protein 705119..706027 Haemophilus somnus 2336 6108408 YP_001783948.1 CDS HSM_0610 NC_010519.1 706031 709363 D PFAM: N-6 DNA methylase; KEGG: cjr:CJE1195 type II restriction-modification enzyme; N-6 DNA methylase 706031..709363 Haemophilus somnus 2336 6108409 YP_001783949.1 CDS HSM_0611 NC_010519.1 709456 709941 D KEGG: cje:Cj1051c restriction modification enzyme; restriction modification enzyme 709456..709941 Haemophilus somnus 2336 6108411 YP_001783950.1 CDS HSM_0612 NC_010519.1 710510 711667 D PFAM: sodium/calcium exchanger membrane region; KEGG: hso:HS_0343 calcium/proton antiporter; sodium/calcium exchanger membrane region 710510..711667 Haemophilus somnus 2336 6108412 YP_001783951.1 CDS HSM_0613 NC_010519.1 711739 712743 D PFAM: conserved hypothetical protein 698; KEGG: hso:HS_0344 membrane protein; hypothetical protein 711739..712743 Haemophilus somnus 2336 6108413 YP_001783952.1 CDS HSM_0614 NC_010519.1 712760 713872 D PFAM: PhoH family protein; KEGG: hso:HS_0345 PhoH-like ATP-binding protein; PhoH family protein 712760..713872 Haemophilus somnus 2336 6108414 YP_001783953.1 CDS HSM_0615 NC_010519.1 713894 714358 D PFAM: protein of unknown function UPF0054; KEGG: hso:HS_0346 conserved hypothetical protein; hypothetical protein 713894..714358 Haemophilus somnus 2336 6108415 YP_001783954.1 CDS HSM_0616 NC_010519.1 714369 716300 D PFAM: protein of unknown function DUF699 ATPase KEGG: hso:HS_0347 acetyltransferase; hypothetical protein 714369..716300 Haemophilus somnus 2336 6108416 YP_001783955.1 CDS HSM_0617 NC_010519.1 716333 716506 D KEGG: hso:HS_0347a hypothetical protein; hypothetical protein 716333..716506 Haemophilus somnus 2336 6108417 YP_001783956.1 CDS HSM_0618 NC_010519.1 716651 718234 D PFAM: carbon starvation protein CstA; KEGG: hso:HS_0348 carbon starvation protein A; carbon starvation protein CstA 716651..718234 Haemophilus somnus 2336 6108418 YP_001783957.1 CDS HSM_0619 NC_010519.1 718457 718915 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 718457..718915 Haemophilus somnus 2336 6108419 YP_001783958.1 CDS mraW NC_010519.1 719027 719992 D TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: hso:HS_0350 S-adenosyl-methyltransferase; S-adenosyl-methyltransferase MraW 719027..719992 Haemophilus somnus 2336 6108420 YP_001783959.1 CDS HSM_0621 NC_010519.1 719992 720312 D PFAM: cell division protein FtsL; KEGG: hso:HS_0351 cell division protein; cell division protein FtsL 719992..720312 Haemophilus somnus 2336 6108422 YP_001783960.1 CDS HSM_0622 NC_010519.1 720337 722136 D PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: hso:HS_0352 peptidoglycan glycosyltransferase (peptidoglycan synthetase); peptidoglycan glycosyltransferase 720337..722136 Haemophilus somnus 2336 6108423 YP_001783961.1 CDS murE NC_010519.1 722152 723639 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 722152..723639 Haemophilus somnus 2336 6108424 YP_001783962.1 CDS HSM_0624 NC_010519.1 723720 725111 D TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: hso:HS_0354 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (MurF synthetase); UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase 723720..725111 Haemophilus somnus 2336 6108425 YP_001783963.1 CDS mraY NC_010519.1 725105 726190 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 725105..726190 Haemophilus somnus 2336 6108426 YP_001783964.1 CDS murD NC_010519.1 726199 727509 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 726199..727509 Haemophilus somnus 2336 6108427 YP_001783965.1 CDS HSM_0627 NC_010519.1 727523 728707 D TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: hso:HS_0357 cell division protein; cell division protein FtsW 727523..728707 Haemophilus somnus 2336 6108428 YP_001783966.1 CDS murG NC_010519.1 728723 729796 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 728723..729796 Haemophilus somnus 2336 6108429 YP_001783967.1 CDS murC NC_010519.1 729850 731280 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 729850..731280 Haemophilus somnus 2336 6108430 YP_001783968.1 CDS ddl NC_010519.1 731325 732251 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 731325..732251 Haemophilus somnus 2336 6108431 YP_001783969.1 CDS HSM_0631 NC_010519.1 732252 733025 D PFAM: cell division protein FtsQ; polypeptide-transport-associated domain protein FtsQ-type; KEGG: hso:HS_0361 cell division protein; cell division protein FtsQ 732252..733025 Haemophilus somnus 2336 6108433 YP_001783970.1 CDS HSM_0632 NC_010519.1 733056 734330 D PFAM: cell division protein FtsA; KEGG: hso:HS_0362 ATP-binding cell division protein; cell division protein FtsA 733056..734330 Haemophilus somnus 2336 6108434 YP_001783971.1 CDS HSM_0633 NC_010519.1 734417 735631 D TIGRFAM: cell division protein FtsZ; PFAM: Tubulin/FtsZ GTPase; Tubulin/FtsZ domain protein; KEGG: hso:HS_0363 cell division protein; cell division protein FtsZ 734417..735631 Haemophilus somnus 2336 6108435 YP_001783972.1 CDS lpxC NC_010519.1 735672 736589 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 735672..736589 Haemophilus somnus 2336 6108436 YP_001783973.1 CDS HSM_0635 NC_010519.1 736713 737870 D TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; chorismate mutase; KEGG: hso:HS_0365 bifunctional P-protein/chorismate mutase; chorismate mutase 736713..737870 Haemophilus somnus 2336 6108437 YP_001783974.1 CDS HSM_0636 NC_010519.1 737932 738720 R PFAM: hypothetical protein; SMART: hypothetical protein; KEGG: hso:HS_0366 DNA uptake lipoprotein; hypothetical protein complement(737932..738720) Haemophilus somnus 2336 6108438 YP_001783975.1 CDS rluD NC_010519.1 738821 739795 D responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 738821..739795 Haemophilus somnus 2336 6108439 YP_001783976.1 CDS HSM_0638 NC_010519.1 739797 740537 D PFAM: protein of unknown function DUF152; KEGG: hso:HS_0368 conserved hypothetical protein; hypothetical protein 739797..740537 Haemophilus somnus 2336 6108440 YP_001783977.1 CDS HSM_0639 NC_010519.1 740590 741540 R TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; KEGG: hso:HS_0369 cysteine synthase; cysteine synthase A complement(740590..741540) Haemophilus somnus 2336 6108441 YP_001783978.1 CDS HSM_0640 NC_010519.1 741659 742432 R role in sulfur assimilation; sulfate transporter CysZ complement(741659..742432) Haemophilus somnus 2336 6108442 YP_001783979.1 CDS HSM_0641 NC_010519.1 742592 743599 D interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 742592..743599 Haemophilus somnus 2336 6108444 YP_001783980.1 CDS HSM_0642 NC_010519.1 744112 745782 D ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 744112..745782 Haemophilus somnus 2336 6108445 YP_001783981.1 CDS HSM_0643 NC_010519.1 745806 746348 D KEGG: msu:MS1887 hypothetical protein; hypothetical protein 745806..746348 Haemophilus somnus 2336 6108446 YP_001783982.1 CDS HSM_0644 NC_010519.1 746757 747233 R PFAM: ABC transporter; KEGG: vpa:VPA1495 ABC transporter ATP-binding protein; ABC transporter complement(746757..747233) Haemophilus somnus 2336 6108447 YP_001783983.1 CDS HSM_0645 NC_010519.1 747563 747808 R PFAM: peptidase S24 S26A and S26B; KEGG: mgm:Mmc1_2924 phage repressor; phage repressor complement(747563..747808) Haemophilus somnus 2336 6108448 YP_001783984.1 CDS HSM_0646 NC_010519.1 748000 748527 R hypothetical protein complement(748000..748527) Haemophilus somnus 2336 6108449 YP_001783985.1 CDS HSM_0647 NC_010519.1 748861 750849 D PFAM: Integrase catalytic region; MuA-transposase/repressor protein CI DNA-binding; transposase-like Mu; KEGG: ecs:ECs4945 phage transposase; transposase 748861..750849 Haemophilus somnus 2336 6108450 YP_001783986.1 CDS HSM_0648 NC_010519.1 750853 751728 D PFAM: helix-turn-helix domain protein; KEGG: nmc:NMC1048 phage transposase; helix-turn-helix domain-containing protein 750853..751728 Haemophilus somnus 2336 6108451 YP_001783987.1 CDS HSM_0649 NC_010519.1 751951 752166 D hypothetical protein 751951..752166 Haemophilus somnus 2336 6108452 YP_001783988.1 CDS HSM_0650 NC_010519.1 752175 752369 D hypothetical protein 752175..752369 Haemophilus somnus 2336 6108453 YP_001783989.1 CDS HSM_0651 NC_010519.1 752606 753223 D KEGG: hdu:HD0097 hypothetical protein; hypothetical protein 752606..753223 Haemophilus somnus 2336 6108455 YP_001783990.1 CDS HSM_0652 NC_010519.1 753390 753710 D hypothetical protein 753390..753710 Haemophilus somnus 2336 6108456 YP_001783991.1 CDS HSM_0653 NC_010519.1 754070 754237 D KEGG: hdu:HD0100 hypothetical protein; hypothetical protein 754070..754237 Haemophilus somnus 2336 6108457 YP_001783992.1 CDS HSM_0654 NC_010519.1 754404 754796 D hypothetical protein 754404..754796 Haemophilus somnus 2336 6108458 YP_001783993.1 CDS HSM_0655 NC_010519.1 754904 755254 D KEGG: hdu:HD0107 hypothetical protein; hypothetical protein 754904..755254 Haemophilus somnus 2336 6108459 YP_001783994.1 CDS HSM_0656 NC_010519.1 755381 755755 D KEGG: hdu:HD1519 hypothetical protein; hypothetical protein 755381..755755 Haemophilus somnus 2336 6108460 YP_001783995.1 CDS HSM_0657 NC_010519.1 755742 756152 D PFAM: protein of unknown function DUF1018; KEGG: hdu:HD0497 hypothetical protein; hypothetical protein 755742..756152 Haemophilus somnus 2336 6108461 YP_001783996.1 CDS HSM_0658 NC_010519.1 756212 756706 D hypothetical protein 756212..756706 Haemophilus somnus 2336 6108462 YP_001783997.1 CDS HSM_0659 NC_010519.1 756891 757319 D KEGG: hdu:HD0500 hypothetical protein; hypothetical protein 756891..757319 Haemophilus somnus 2336 6108463 YP_001783998.1 CDS HSM_0660 NC_010519.1 757402 757938 D PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: Animal peptidoglycan recognition protein PGRP; KEGG: hdu:HD0112 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase 757402..757938 Haemophilus somnus 2336 6108464 YP_001783999.1 CDS HSM_0661 NC_010519.1 758081 758323 D KEGG: hdu:HD0503 hypothetical protein; hypothetical protein 758081..758323 Haemophilus somnus 2336 6108466 YP_001784000.1 CDS HSM_0662 NC_010519.1 758320 758574 D hypothetical protein 758320..758574 Haemophilus somnus 2336 6108467 YP_001784001.1 CDS HSM_0663 NC_010519.1 758685 758939 D KEGG: nma:NMA1856 hypothetical protein; hypothetical protein 758685..758939 Haemophilus somnus 2336 6108468 YP_001784002.1 CDS HSM_0664 NC_010519.1 758939 759193 D KEGG: hdu:HD0507 hypothetical protein; hypothetical protein 758939..759193 Haemophilus somnus 2336 6108469 YP_001784003.1 CDS HSM_0665 NC_010519.1 759194 759697 D PFAM: protein of unknown function DUF1804; KEGG: hdu:HD0509 conserved DNA-binding protein; hypothetical protein 759194..759697 Haemophilus somnus 2336 6108470 YP_001784004.1 CDS HSM_0666 NC_010519.1 759800 761443 D TIGRFAM: phage uncharacterized protein; KEGG: nma:NMA1313 hypothetical protein; phage lprotein 759800..761443 Haemophilus somnus 2336 6108471 YP_001784005.1 CDS HSM_0667 NC_010519.1 761447 763105 D PFAM: protein of unknown function DUF935; KEGG: hdu:HD0514 hypothetical protein; hypothetical protein 761447..763105 Haemophilus somnus 2336 6108472 YP_001784006.1 CDS HSM_0668 NC_010519.1 763092 764366 D TIGRFAM: phage head morphogenesis protein, SPP1 gp7 family; PFAM: phage head morphogenesis protein SPP1 gp7; KEGG: hdu:HD0515 hypothetical protein; SPP1 family phage head morphogenesis protein 763092..764366 Haemophilus somnus 2336 6108473 YP_001784007.1 CDS HSM_0669 NC_010519.1 764940 765425 D TIGRFAM: phage virion morphogenesis protein; PFAM: phage virion morphogenesis ( tail completion) protein; KEGG: hin:HI1568 G protein; phage virion morphogenesis protein 764940..765425 Haemophilus somnus 2336 6108474 YP_001784008.1 CDS HSM_0670 NC_010519.1 765686 766726 D KEGG: nme:NMB1098 I protein; hypothetical protein 765686..766726 Haemophilus somnus 2336 6108475 YP_001784009.1 CDS HSM_0671 NC_010519.1 766731 767657 D KEGG: hdu:HD0519 bacteriophage mu T protein homolog; bacteriophage mu T-like protein 766731..767657 Haemophilus somnus 2336 6108477 YP_001784010.1 CDS HSM_0672 NC_010519.1 767701 768171 D KEGG: hdu:HD0520 hypothetical protein; hypothetical protein 767701..768171 Haemophilus somnus 2336 6108478 YP_001784011.1 CDS HSM_0673 NC_010519.1 768174 768608 D PFAM: protein of unknown function DUF1320; KEGG: nme:NMB1101 hypothetical protein; hypothetical protein 768174..768608 Haemophilus somnus 2336 6108479 YP_001784012.1 CDS HSM_0674 NC_010519.1 768520 769233 D PFAM: Domain of unknown function DUF1834; KEGG: nme:NMB1102 hypothetical protein; hypothetical protein 768520..769233 Haemophilus somnus 2336 6108480 YP_001784013.1 CDS HSM_0675 NC_010519.1 769230 769412 D KEGG: dvu:DVU2715 hypothetical protein; hypothetical protein 769230..769412 Haemophilus somnus 2336 6108481 YP_001784014.1 CDS HSM_0676 NC_010519.1 769405 770820 D PFAM: bacteriophage Mu tail sheath family protein; KEGG: nme:NMB1104 phage sheath protein; bacteriophage Mu tail sheath family protein 769405..770820 Haemophilus somnus 2336 6108482 YP_001784015.1 CDS HSM_0677 NC_010519.1 770830 771204 D KEGG: nme:NMB1105 hypothetical protein; hypothetical protein 770830..771204 Haemophilus somnus 2336 6108483 YP_001784016.1 CDS HSM_0678 NC_010519.1 771204 771575 D hypothetical protein 771204..771575 Haemophilus somnus 2336 6108484 YP_001784017.1 CDS HSM_0679 NC_010519.1 771838 774255 D KEGG: nme:NMB1108 hypothetical protein; hypothetical protein 771838..774255 Haemophilus somnus 2336 6108485 YP_001784018.1 CDS HSM_0680 NC_010519.1 774258 775589 D KEGG: nme:NMB1109 phage virion protein; phage virion protein 774258..775589 Haemophilus somnus 2336 6108486 YP_001784019.1 CDS HSM_0681 NC_010519.1 775579 776724 D PFAM: bacteriophage Mu P family protein; KEGG: nma:NMA1320 hypothetical protein; bacteriophage Mu P family protein 775579..776724 Haemophilus somnus 2336 6108488 YP_001784020.1 CDS HSM_0682 NC_010519.1 776724 777380 D TIGRFAM: phage baseplate assembly protein V; PFAM: bacteriophage Mu Gp45 domain protein; KEGG: nma:NMA1321 hypothetical protein; phage baseplate assembly protein V 776724..777380 Haemophilus somnus 2336 6108489 YP_001784021.1 CDS HSM_0683 NC_010519.1 777459 777809 D PFAM: phage GP46 family protein; KEGG: nma:NMA1322 hypothetical protein; phage GP46 family protein 777459..777809 Haemophilus somnus 2336 6108490 YP_001784022.1 CDS HSM_0684 NC_010519.1 777823 778887 D PFAM: Baseplate J family protein; KEGG: nma:NMA1323 hypothetical protein; baseplate J family protein 777823..778887 Haemophilus somnus 2336 6108491 YP_001784023.1 CDS HSM_0685 NC_010519.1 778887 779474 D KEGG: nmc:NMC1057 hypothetical protein; hypothetical protein 778887..779474 Haemophilus somnus 2336 6108492 YP_001784024.1 CDS HSM_0686 NC_010519.1 779478 781436 D PFAM: phage tail fiber repeat 2 protein; phage Tail Collar domain protein; KEGG: hit:NTHI1857 probable tail fiber protein; phage tail collar domain-containing protein 779478..781436 Haemophilus somnus 2336 6108493 YP_001784025.1 CDS HSM_0687 NC_010519.1 781433 782047 D KEGG: hit:NTHI1553 hypothetical protein; hypothetical protein 781433..782047 Haemophilus somnus 2336 6108494 YP_001784026.1 CDS HSM_0688 NC_010519.1 782040 782534 D KEGG: hit:NTHI1554 hypothetical protein; hypothetical protein 782040..782534 Haemophilus somnus 2336 6108495 YP_001784027.1 CDS HSM_0689 NC_010519.1 782902 783660 D KEGG: mmy:MSC_0780 C5 methylase (MAV1virus-like); C5 methylase 782902..783660 Haemophilus somnus 2336 6108496 YP_001784028.1 CDS HSM_0690 NC_010519.1 783647 784483 D KEGG: hdu:HD0156 hypothetical protein; hypothetical protein 783647..784483 Haemophilus somnus 2336 6108497 YP_001784029.1 CDS HSM_0691 NC_010519.1 784504 784692 R KEGG: mxa:MXAN_1831 hypothetical protein; hypothetical protein complement(784504..784692) Haemophilus somnus 2336 6108499 YP_001784030.1 CDS HSM_0692 NC_010519.1 784696 785010 R hypothetical protein complement(784696..785010) Haemophilus somnus 2336 6108500 YP_001784031.1 CDS HSM_0693 NC_010519.1 785160 786344 R PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: vch:VCA0977 ABC transporter ATP-binding protein; ABC transporter complement(785160..786344) Haemophilus somnus 2336 6108501 YP_001784032.1 CDS HSM_0694 NC_010519.1 786356 787276 R PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hit:NTHI1288 oligopeptide transporter permease protein; binding-protein-dependent transporters inner membrane component complement(786356..787276) Haemophilus somnus 2336 6108502 YP_001784033.1 CDS HSM_0695 NC_010519.1 787286 788209 R PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hin:HI1123 oligopeptide transporter permease protein; alkaline phosphatase complement(787286..788209) Haemophilus somnus 2336 6108503 YP_001784034.1 CDS HSM_0696 NC_010519.1 788322 789959 R PFAM: extracellular solute-binding protein family 5; KEGG: hit:NTHI1292 periplasmic oligopeptide-binding protein; extracellular solute-binding protein complement(788322..789959) Haemophilus somnus 2336 6108504 YP_001784035.1 CDS HSM_0697 NC_010519.1 790118 791773 R PFAM: extracellular solute-binding protein family 5; KEGG: hit:NTHI1292 periplasmic oligopeptide-binding protein; extracellular solute-binding protein complement(790118..791773) Haemophilus somnus 2336 6108505 YP_001784036.1 CDS HSM_0698 NC_010519.1 792010 792672 D PFAM: TrkA-N domain protein; KEGG: hso:HS_0375 K+ transporter; TrkA domain-containing protein 792010..792672 Haemophilus somnus 2336 6108506 YP_001784037.1 CDS HSM_0699 NC_010519.1 792662 793981 D TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: hso:HS_0376 cation transporter; TrkH family potassium uptake protein 792662..793981 Haemophilus somnus 2336 6108507 YP_001784038.1 CDS ligA NC_010519.1 794099 796102 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(794099..796102) Haemophilus somnus 2336 6108508 YP_001784039.1 CDS HSM_0701 NC_010519.1 796229 797578 R TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter; KEGG: hso:HS_0378 gluconate permease; gluconate transporter complement(796229..797578) Haemophilus somnus 2336 6108511 YP_001784040.1 CDS HSM_0702 NC_010519.1 797600 798364 R Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase complement(797600..798364) Haemophilus somnus 2336 6108512 YP_001784041.1 CDS HSM_0703 NC_010519.1 798375 799418 R NAD-binding; L-idonate 5-dehydrogenase complement(798375..799418) Haemophilus somnus 2336 6108513 YP_001784042.1 CDS HSM_0704 NC_010519.1 799663 800181 D TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase; KEGG: hso:HS_0379 gluconokinase (gluconate kinase); carbohydrate kinase 799663..800181 Haemophilus somnus 2336 6108514 YP_001784043.1 CDS HSM_0705 NC_010519.1 800671 801699 D TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: hso:HS_0380 conserved hypothetical protein; TRAP transporter solute receptor TAXI family protein 800671..801699 Haemophilus somnus 2336 6108515 YP_001784044.1 CDS HSM_0706 NC_010519.1 801721 802194 D PFAM: Domain of unknown function DUF1850; KEGG: hso:HS_0381 hypothetical protein; hypothetical protein 801721..802194 Haemophilus somnus 2336 6108516 YP_001784045.1 CDS HSM_0707 NC_010519.1 802187 804163 D TIGRFAM: TRAP transporter 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_0382 conserved integral membrane protein; TRAP transporter 4TM/12TM fusion protein 802187..804163 Haemophilus somnus 2336 6108517 YP_001784046.1 CDS HSM_0708 NC_010519.1 804395 815419 R PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1085 large adhesin; YadA domain-containing protein complement(804395..815419) Haemophilus somnus 2336 6108518 YP_001784047.1 CDS prfC NC_010519.1 816087 817667 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 816087..817667 Haemophilus somnus 2336 6108519 YP_001784048.1 CDS HSM_0710 NC_010519.1 817784 820231 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(817784..820231) Haemophilus somnus 2336 6108520 YP_001784049.1 CDS HSM_0711 NC_010519.1 820381 821013 D Represses a number of genes involved in the response to DNA damage; LexA repressor 820381..821013 Haemophilus somnus 2336 6108522 YP_001784050.1 CDS ndk NC_010519.1 821100 821525 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(821100..821525) Haemophilus somnus 2336 6108523 YP_001784051.1 CDS HSM_0713 NC_010519.1 821537 822835 R catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B complement(821537..822835) Haemophilus somnus 2336 6108524 YP_001784052.1 CDS leuD NC_010519.1 822945 823547 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(822945..823547) Haemophilus somnus 2336 6108525 YP_001784053.1 CDS HSM_0715 NC_010519.1 823557 824966 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(823557..824966) Haemophilus somnus 2336 6108526 YP_001784054.1 CDS HSM_0716 NC_010519.1 825066 826142 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(825066..826142) Haemophilus somnus 2336 6108527 YP_001784055.1 CDS HSM_0717 NC_010519.1 826166 827719 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(826166..827719) Haemophilus somnus 2336 6108528 YP_001784056.1 CDS HSM_0718 NC_010519.1 828316 828969 D ATP-binding protein; required for proper cytochrome C maturation; cytochrome C biogenesis protein CcmA 828316..828969 Haemophilus somnus 2336 6108529 YP_001784057.1 CDS HSM_0719 NC_010519.1 828966 829631 D TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: hso:HS_0394 heme ABC transporter permease (heme exporter protein B); heme exporter protein CcmB 828966..829631 Haemophilus somnus 2336 6108530 YP_001784058.1 CDS HSM_0720 NC_010519.1 829678 830412 D TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome C assembly protein; KEGG: hso:HS_0395 heme ABC transporter permease (heme exporter protein C); heme exporter protein CcmC 829678..830412 Haemophilus somnus 2336 6108531 YP_001784059.1 CDS HSM_0721 NC_010519.1 830422 830634 D PFAM: Heme exporter protein D (CcmD); KEGG: hso:HS_0396 heme ABC transporter substrate-binding protein (heme exporter protein D); Heme exporter protein CcmD 830422..830634 Haemophilus somnus 2336 6108533 YP_001784060.1 CDS HSM_0722 NC_010519.1 830631 831155 D CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome C maturation system; periplasmic protein anchored to the inner membrane; cytochrome C biogenesis protein CcmE 830631..831155 Haemophilus somnus 2336 6108534 YP_001784061.1 CDS HSM_0723 NC_010519.1 831152 833101 D TIGRFAM: cytochrome C biogenesis protein CcmF; PFAM: cytochrome C assembly protein; KEGG: hso:HS_0398 cytochrome C biogenesis protein F; cytochrome C biogenesis protein CcmF 831152..833101 Haemophilus somnus 2336 6108535 YP_001784062.1 CDS HSM_0724 NC_010519.1 833105 833650 D TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: hso:HS_0399 thiol:disulfide interchange protein; periplasmic protein thiol--disulfide oxidoreductase DsbE 833105..833650 Haemophilus somnus 2336 6108536 YP_001784063.1 CDS HSM_0725 NC_010519.1 833647 834117 D PFAM: cytochrome C biogenesis protein; KEGG: hso:HS_0400 cytochrome C biogenesis protein H; cytochrome C biogenesis protein 833647..834117 Haemophilus somnus 2336 6108537 YP_001784064.1 CDS HSM_0726 NC_010519.1 834121 835005 D KEGG: hso:HS_0401 cytochrome C biogenesis protein, with TPR repeats; TPR repeat-containing cytochrome C biogenesis protein 834121..835005 Haemophilus somnus 2336 6108538 YP_001784065.1 CDS HSM_0727 NC_010519.1 835018 836874 D PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: hso:HS_0402 sensor histidine kinase; multi-sensor hybrid histidine kinase 835018..836874 Haemophilus somnus 2336 6108539 YP_001784066.1 CDS HSM_0728 NC_010519.1 836961 837917 D KEGG: hso:HS_0403 hypothetical protein; hypothetical protein 836961..837917 Haemophilus somnus 2336 6108540 YP_001784067.1 CDS ispG NC_010519.1 837924 839030 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 837924..839030 Haemophilus somnus 2336 6108541 YP_001784068.1 CDS hisS NC_010519.1 839043 840320 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 839043..840320 Haemophilus somnus 2336 6108542 YP_001784069.1 CDS HSM_0731 NC_010519.1 840331 840942 D KEGG: hso:HS_0406 hypothetical protein; hypothetical protein 840331..840942 Haemophilus somnus 2336 6108544 YP_001784070.1 CDS HSM_0732 NC_010519.1 841000 842445 D TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: hso:HS_0407 succinate-semialdehyde dehydrogenase (NAD(P)+); succinate-semialdehyde dehydrogenase 841000..842445 Haemophilus somnus 2336 6108545 YP_001784071.1 CDS proA NC_010519.1 842601 843857 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(842601..843857) Haemophilus somnus 2336 6108546 YP_001784072.1 CDS HSM_0734 NC_010519.1 843867 844538 R PFAM: protein of unknown function UPF0126; KEGG: hso:HS_0409 hypothetical protein; hypothetical protein complement(843867..844538) Haemophilus somnus 2336 6108547 YP_001784073.1 CDS HSM_0735 NC_010519.1 844699 845286 R catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase complement(844699..845286) Haemophilus somnus 2336 6108548 YP_001784074.1 CDS HSM_0736 NC_010519.1 845348 846376 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(845348..846376) Haemophilus somnus 2336 6108549 YP_001784075.1 CDS HSM_0737 NC_010519.1 846611 847717 D TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: hso:HS_0412 DNA processing chain A; DNA protecting protein DprA 846611..847717 Haemophilus somnus 2336 6108550 YP_001784076.1 CDS HSM_0738 NC_010519.1 847700 848302 R TIGRFAM: methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: hso:HS_0413 conserved methylase; methyltransferase complement(847700..848302) Haemophilus somnus 2336 6108551 YP_001784077.1 CDS HSM_0739 NC_010519.1 848366 849709 D TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase; KEGG: hso:HS_0414 cell division protein; signal recognition particle-docking protein FtsY 848366..849709 Haemophilus somnus 2336 6108552 YP_001784078.1 CDS HSM_0740 NC_010519.1 849871 851442 R TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: hso:HS_0415 conserved membrane protein; integral membrane protein MviN complement(849871..851442) Haemophilus somnus 2336 6108553 YP_001784079.1 CDS rpsT NC_010519.1 851720 851983 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 851720..851983 Haemophilus somnus 2336 6108555 YP_001784080.1 CDS HSM_0742 NC_010519.1 852045 853895 R TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: hso:HS_0417 GTP-binding protein; GTP-binding protein TypA complement(852045..853895) Haemophilus somnus 2336 6108556 YP_001784081.1 CDS HSM_0743 NC_010519.1 854138 855556 D TIGRFAM: glutamine synthetase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: hso:HS_0418 glutamate--ammonia ligase (glutamine synthetase); glutamine synthetase 854138..855556 Haemophilus somnus 2336 6108557 YP_001784082.1 CDS HSM_0744 NC_010519.1 855781 856713 R catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase complement(855781..856713) Haemophilus somnus 2336 6108558 YP_001784083.1 CDS HSM_0745 NC_010519.1 856882 858345 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 856882..858345 Haemophilus somnus 2336 6108559 YP_001784084.1 CDS guaA NC_010519.1 858746 860317 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 858746..860317 Haemophilus somnus 2336 6108560 YP_001784085.1 CDS HSM_0747 NC_010519.1 860564 860824 R KEGG: hso:HS_1709 transposase; transposase complement(860564..860824) Haemophilus somnus 2336 6108561 YP_001784086.1 CDS HSM_0748 NC_010519.1 861565 862353 D PFAM: glycoside hydrolase family 29 (alpha-L-fucosidase); KEGG: hso:HS_0435 alpha-L-fucosidase; alpha-L-fucosidase 861565..862353 Haemophilus somnus 2336 6108562 YP_001784087.1 CDS HSM_0749 NC_010519.1 862512 864500 D PFAM: transferrin binding protein; KEGG: hso:HS_0448 transferrin-binding protein; transferrin binding protein 862512..864500 Haemophilus somnus 2336 6108563 YP_001784088.1 CDS HSM_0750 NC_010519.1 864686 867601 D TIGRFAM: TonB-dependent lactoferrin and transferrin receptors; TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0449 transferrin-binding protein A; TonB-dependent lactoferrin and transferrin receptor 864686..867601 Haemophilus somnus 2336 6108564 YP_001784089.1 CDS HSM_0751 NC_010519.1 867911 869791 D molecular chaperone; heat shock protein 90 867911..869791 Haemophilus somnus 2336 6108566 YP_001784090.1 CDS HSM_0752 NC_010519.1 869979 870227 D KEGG: hso:HS_0454 hypothetical protein; hypothetical protein 869979..870227 Haemophilus somnus 2336 6108567 YP_001784091.1 CDS HSM_0753 NC_010519.1 870266 871000 D PFAM: 4'-phosphopantetheinyl transferase; KEGG: hso:HS_0455 4'-phosphopantetheinyl transferase family protein; 4'-phosphopantetheinyl transferase 870266..871000 Haemophilus somnus 2336 6108568 YP_001784092.1 CDS gltX NC_010519.1 871339 872781 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(871339..872781) Haemophilus somnus 2336 6108868 YP_001784093.1 CDS HSM_0755 NC_010519.1 873478 874698 D PFAM: type II secretion system protein; KEGG: hso:HS_0457 protein transporter; type II secretion system protein 873478..874698 Haemophilus somnus 2336 6108871 YP_001784094.1 CDS HSM_0756 NC_010519.1 874695 875402 D PFAM: peptidase A24A prepilin type IV; KEGG: hso:HS_0458 prepilin peptidase; peptidase A24A prepilin type IV 874695..875402 Haemophilus somnus 2336 6108571 YP_001784095.1 CDS coaE NC_010519.1 875422 876069 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 875422..876069 Haemophilus somnus 2336 6108572 YP_001784096.1 CDS HSM_0758 NC_010519.1 876066 876260 D PFAM: protein of unknown function DUF329; KEGG: hso:HS_0460 hypothetical protein; hypothetical protein 876066..876260 Haemophilus somnus 2336 6108573 YP_001784097.1 CDS HSM_0759 NC_010519.1 876433 876636 D KEGG: hso:HS_0460a hypothetical protein; hypothetical protein 876433..876636 Haemophilus somnus 2336 6108574 YP_001784098.1 CDS HSM_0760 NC_010519.1 876664 878040 D TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: hso:HS_0461 D-alanine glycine permease; amino acid carrier protein 876664..878040 Haemophilus somnus 2336 6108575 YP_001784099.1 CDS HSM_0761 NC_010519.1 878276 878593 D TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: hso:HS_0462 ribosome-associated protein Y; sigma 54 modulation protein/30S ribosomal protein S30EA 878276..878593 Haemophilus somnus 2336 6108577 YP_001784100.1 CDS HSM_0762 NC_010519.1 878797 879336 D TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: hso:HS_0463 hypoxanthine phosphoribosyltransferase (HPRT); hypoxanthine phosphoribosyltransferase 878797..879336 Haemophilus somnus 2336 6108578 YP_001784101.1 CDS HSM_0763 NC_010519.1 879464 880093 R PFAM: manganese and iron superoxide dismutase; KEGG: hso:HS_0464 superoxide dismutase, manganese; superoxide dismutase complement(879464..880093) Haemophilus somnus 2336 6108579 YP_001784102.1 CDS HSM_0764 NC_010519.1 880230 882497 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(880230..882497) Haemophilus somnus 2336 6108580 YP_001784103.1 CDS aspA NC_010519.1 882692 884107 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(882692..884107) Haemophilus somnus 2336 6108581 YP_001784104.1 CDS groES NC_010519.1 884345 884635 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 884345..884635 Haemophilus somnus 2336 6108582 YP_001784105.1 CDS groEL NC_010519.1 884666 886309 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 884666..886309 Haemophilus somnus 2336 6108583 YP_001784106.1 CDS HSM_0768 NC_010519.1 886480 886797 D when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 886480..886797 Haemophilus somnus 2336 6108584 YP_001784107.1 CDS HSM_0769 NC_010519.1 886881 887483 D KEGG: hso:HS_0470 hypothetical protein; hypothetical protein 886881..887483 Haemophilus somnus 2336 6108585 YP_001784108.1 CDS HSM_0770 NC_010519.1 887487 887930 D KEGG: hso:HS_0471 hypothetical protein; hypothetical protein 887487..887930 Haemophilus somnus 2336 6108586 YP_001784109.1 CDS HSM_0771 NC_010519.1 887931 889298 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 887931..889298 Haemophilus somnus 2336 6108588 YP_001784110.1 CDS smpB NC_010519.1 889332 889814 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(889332..889814) Haemophilus somnus 2336 6108589 YP_001784111.1 CDS HSM_0773 NC_010519.1 889942 891417 D TIGRFAM: UbiD family decarboxylase; PFAM: carboxylyase-related protein; KEGG: hso:HS_0474 3-octaprenyl-4-hydroxybenzoate carboxy-lyase (polyprenyl p-hydroxybenzoate decarboxylase); UbiD family decarboxylase 889942..891417 Haemophilus somnus 2336 6108590 YP_001784112.1 CDS HSM_0774 NC_010519.1 891457 892659 R catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase complement(891457..892659) Haemophilus somnus 2336 6108591 YP_001784113.1 CDS HSM_0775 NC_010519.1 892800 893402 D PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; redoxin; KEGG: hso:HS_0476 AhpC/TSA family protein; alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen 892800..893402 Haemophilus somnus 2336 6108592 YP_001784114.1 CDS rpsO NC_010519.1 893587 893856 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(893587..893856) Haemophilus somnus 2336 6108593 YP_001784115.1 CDS HSM_0777 NC_010519.1 894222 895697 D PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_1282 permease, major facilitator superfamily; major facilitator transporter 894222..895697 Haemophilus somnus 2336 6108594 YP_001784116.1 CDS HSM_0778 NC_010519.1 896006 896815 D KEGG: hso:HS_1281 permease; permease 896006..896815 Haemophilus somnus 2336 6108595 YP_001784117.1 CDS HSM_0779 NC_010519.1 896934 897281 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(896934..897281) Haemophilus somnus 2336 6108596 YP_001784118.1 CDS HSM_0780 NC_010519.1 897292 897696 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(897292..897696) Haemophilus somnus 2336 6108597 YP_001784119.1 CDS HSM_0781 NC_010519.1 897707 898477 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(897707..898477) Haemophilus somnus 2336 6108599 YP_001784120.1 CDS HSM_0782 NC_010519.1 898470 900269 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(898470..900269) Haemophilus somnus 2336 6108600 YP_001784121.1 CDS HSM_0783 NC_010519.1 900582 901553 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 900582..901553 Haemophilus somnus 2336 6108601 YP_001784122.1 CDS HSM_0784 NC_010519.1 901607 903193 R PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: hso:HS_1275 FAD flavoprotein oxidase; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein complement(901607..903193) Haemophilus somnus 2336 6108602 YP_001784123.1 CDS HSM_0785 NC_010519.1 903274 904080 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1274 ABC transporter ATP-binding protein; ABC transporter complement(903274..904080) Haemophilus somnus 2336 6108603 YP_001784124.1 CDS HSM_0786 NC_010519.1 904084 906036 R PFAM: binding-protein-dependent transporters inner membrane component; ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: hso:HS_1273 ABC transporter permease/ATP-binding protein; ABC transporter complement(904084..906036) Haemophilus somnus 2336 6108604 YP_001784125.1 CDS HSM_0787 NC_010519.1 906036 906989 R PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_1272 ABC transporter permease; binding-protein-dependent transporters inner membrane component complement(906036..906989) Haemophilus somnus 2336 6108605 YP_001784126.1 CDS HSM_0788 NC_010519.1 907127 908713 R PFAM: extracellular solute-binding protein family 5; KEGG: hso:HS_1271 ABC transporter periplasmic binding protein; extracellular solute-binding protein complement(907127..908713) Haemophilus somnus 2336 6108606 YP_001784127.1 CDS HSM_0789 NC_010519.1 909036 911534 R catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase complement(909036..911534) Haemophilus somnus 2336 6108607 YP_001784128.1 CDS HSM_0790 NC_010519.1 911817 912116 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein complement(911817..912116) Haemophilus somnus 2336 6108608 YP_001784129.1 CDS HSM_0791 NC_010519.1 912136 912600 R PFAM: thioesterase superfamily protein; KEGG: hso:HS_1268 acyl-CoA hydrolase; thioesterase superfamily protein complement(912136..912600) Haemophilus somnus 2336 6108610 YP_001784130.1 CDS HSM_0792 NC_010519.1 912610 913149 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(912610..913149) Haemophilus somnus 2336 6108611 YP_001784131.1 CDS HSM_0793 NC_010519.1 913149 913889 R KEGG: hso:HS_1266 membrane protein; hypothetical protein complement(913149..913889) Haemophilus somnus 2336 6108612 YP_001784132.1 CDS HSM_0796 NC_010519.1 914974 915417 D binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 914974..915417 Haemophilus somnus 2336 6108614 YP_001784133.1 CDS HSM_0797 NC_010519.1 915439 915894 D KEGG: hso:HS_1263 Haemophilus-specific protein, uncharacterized; hypothetical protein 915439..915894 Haemophilus somnus 2336 6108615 YP_001784134.1 CDS HSM_0798 NC_010519.1 915983 916807 D PFAM: filamentation induced by cAMP protein Fic; KEGG: hso:HS_1262 hypothetical protein; filamentation induced by cAMP protein fic 915983..916807 Haemophilus somnus 2336 6108616 YP_001784135.1 CDS HSM_0799 NC_010519.1 916809 917003 D KEGG: hso:HS_1261 hypothetical protein; hypothetical protein 916809..917003 Haemophilus somnus 2336 6108617 YP_001784136.1 CDS HSM_0800 NC_010519.1 917206 917652 D KEGG: hso:HS_1374 Haemophilus-specific protein, uncharacterized; hypothetical protein 917206..917652 Haemophilus somnus 2336 6108618 YP_001784137.1 CDS HSM_0801 NC_010519.1 917815 918786 D TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: hpy:HP1121 cytosine specific DNA methyltransferase; DNA-cytosine methyltransferase 917815..918786 Haemophilus somnus 2336 6108621 YP_001784138.1 CDS HSM_0802 NC_010519.1 918797 919540 D KEGG: hpj:jhp1049 hypothetical protein; hypothetical protein 918797..919540 Haemophilus somnus 2336 6108622 YP_001784139.1 CDS valS NC_010519.1 919587 922451 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 919587..922451 Haemophilus somnus 2336 6108623 YP_001784140.1 CDS truA NC_010519.1 922507 923316 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(922507..923316) Haemophilus somnus 2336 6108624 YP_001784141.1 CDS HSM_0805 NC_010519.1 923347 924258 R Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase complement(923347..924258) Haemophilus somnus 2336 6108625 YP_001784142.1 CDS HSM_0806 NC_010519.1 924369 925268 R KEGG: hit:NTHI0936 HTH-type transcriptional regulator; HTH-type transcriptional regulator complement(924369..925268) Haemophilus somnus 2336 6108626 YP_001784143.1 CDS HSM_0807 NC_010519.1 925565 926212 D TIGRFAM: 3-oxoacid CoA-transferase, subunit alpha; KEGG: hit:NTHI0935 acetate CoA-transferase subunit alpha; 3-oxoacid CoA-transferase subunit A 925565..926212 Haemophilus somnus 2336 6108627 YP_001784144.1 CDS HSM_0808 NC_010519.1 926230 926889 D TIGRFAM: 3-oxoacid CoA-transferase subunit beta; KEGG: hit:NTHI0934 acetate CoA-transferase subunit beta; 3-oxoacid CoA-transferase subunit B 926230..926889 Haemophilus somnus 2336 6108628 YP_001784145.1 CDS HSM_0809 NC_010519.1 926900 928243 D KEGG: hin:HI0772 short-chain fatty acids transporter; short-chain fatty acids transporter 926900..928243 Haemophilus somnus 2336 6108629 YP_001784146.1 CDS HSM_0810 NC_010519.1 928335 929516 D TIGRFAM: acetyl-CoA acetyltransferase; KEGG: ecp:ECP_2268 acetyl-CoA acetyltransferase; acetyl-CoA acetyltransferase 928335..929516 Haemophilus somnus 2336 6108630 YP_001784147.1 CDS HSM_0811 NC_010519.1 929544 930302 D TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KEGG: csa:Csal_1825 3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase 929544..930302 Haemophilus somnus 2336 6108632 YP_001784148.1 CDS HSM_0812 NC_010519.1 930373 931758 D PFAM: gluconate transporter; citrate transporter; KEGG: pcr:Pcryo_1595 GntP family transporter; citrate transporter 930373..931758 Haemophilus somnus 2336 6108633 YP_001784149.1 CDS znuA NC_010519.1 931926 933092 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein complement(931926..933092) Haemophilus somnus 2336 6108634 YP_001784150.1 CDS HSM_0814 NC_010519.1 933185 933952 R PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: hso:HS_1255 hypothetical protein; UBA/THIF-type NAD/FAD binding protein complement(933185..933952) Haemophilus somnus 2336 6108635 YP_001784151.1 CDS mltA NC_010519.1 933952 935043 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(933952..935043) Haemophilus somnus 2336 6108636 YP_001784152.1 CDS HSM_0816 NC_010519.1 935316 936224 R catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase complement(935316..936224) Haemophilus somnus 2336 6108637 YP_001784153.1 CDS HSM_0817 NC_010519.1 936328 937056 D PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pmu:PM1376 hypothetical Rhizobium sp.; transcriptional regulator 936328..937056 Haemophilus somnus 2336 6108638 YP_001784154.1 CDS HSM_0818 NC_010519.1 937089 938084 R PFAM: PfkB domain protein; KEGG: pmu:PM1372 sugar kinase; ribokinase complement(937089..938084) Haemophilus somnus 2336 6108639 YP_001784155.1 CDS HSM_0819 NC_010519.1 938071 938955 R TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; KEGG: pmu:PM1373 fructose-bisphosphate aldolase; hypothetical protein complement(938071..938955) Haemophilus somnus 2336 6108640 YP_001784156.1 CDS HSM_0820 NC_010519.1 938946 939626 R PFAM: protein of unknown function DUF1498; KEGG: pmu:PM1374 unknown; hypothetical protein complement(938946..939626) Haemophilus somnus 2336 6108641 YP_001784157.1 CDS HSM_0821 NC_010519.1 939733 940662 R PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: pmu:PM1377 D-ribose binding periplasmic protein precursor; periplasmic binding protein/LacI transcriptional regulator complement(939733..940662) Haemophilus somnus 2336 6108643 YP_001784158.1 CDS HSM_0822 NC_010519.1 940717 941685 R PFAM: inner-membrane translocator; KEGG: pmu:PM1378 ribose ABC transporter permease; monosaccharide-transporting ATPase complement(940717..941685) Haemophilus somnus 2336 6108644 YP_001784159.1 CDS HSM_0823 NC_010519.1 941708 943216 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: pmu:PM1379 ribose ABC transporter ATP-binding protein; ABC transporter complement(941708..943216) Haemophilus somnus 2336 6108645 YP_001784160.1 CDS HSM_0824 NC_010519.1 943549 945978 D SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: pmu:PM1380 hybrid histidine protein kinase-phosphate acceptor regulatory protein; integral membrane sensor hybrid histidine kinase 943549..945978 Haemophilus somnus 2336 6108646 YP_001784161.1 CDS HSM_0825 NC_010519.1 946353 948230 D TIGRFAM: PTS system, mannitol-specific IIC subunit; KEGG: hso:HS_1252 mannitol-specific IIABC component, PTS system; PTS system mannitol-specific transporter subunit IIC 946353..948230 Haemophilus somnus 2336 6108647 YP_001784162.1 CDS HSM_0826 NC_010519.1 948303 949460 D KEGG: hso:HS_1251 mannitol 1-phosphate 5-dehydrogenase; mannitol-1-phosphate 5-dehydrogenase 948303..949460 Haemophilus somnus 2336 6108648 YP_001784163.1 CDS mtlR NC_010519.1 949535 950050 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 949535..950050 Haemophilus somnus 2336 6108649 YP_001784164.1 CDS HSM_0828 NC_010519.1 950147 951523 R TIGRFAM: UDP-N-acetylmuramate; KEGG: hso:HS_1249 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamayl-medo- diaminopimelate; UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase complement(950147..951523) Haemophilus somnus 2336 6108650 YP_001784165.1 CDS HSM_0829 NC_010519.1 951664 952671 D catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 951664..952671 Haemophilus somnus 2336 6108651 YP_001784166.1 CDS HSM_0832 NC_010519.1 956232 956936 D alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 956232..956936 Haemophilus somnus 2336 6108654 YP_001784167.1 CDS HSM_0833 NC_010519.1 956947 958239 D TIGRFAM: anaerobic c4-dicarboxylate antiporter, DcuC family; PFAM: C4-dicarboxylate anaerobic carrier; citrate transporter; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_1244 permease, C4-dicarboxylate transporter; anaerobic c4-dicarboxylate antiporter 956947..958239 Haemophilus somnus 2336 6108655 YP_001784168.1 CDS HSM_0836 NC_010519.1 959761 961557 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 959761..961557 Haemophilus somnus 2336 6108657 YP_001784169.1 CDS HSM_0837 NC_010519.1 961568 962599 D TIGRFAM: signal peptidase I; PFAM: peptidase S24 S26A and S26B; KEGG: hso:HS_1241 signal peptidase I; signal peptidase I 961568..962599 Haemophilus somnus 2336 6108658 YP_001784170.1 CDS rnc NC_010519.1 962805 963476 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 962805..963476 Haemophilus somnus 2336 6108659 YP_001784171.1 CDS era NC_010519.1 963517 964431 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 963517..964431 Haemophilus somnus 2336 6108660 YP_001784172.1 CDS gmhA NC_010519.1 964456 965043 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 964456..965043 Haemophilus somnus 2336 6108661 YP_001784173.1 CDS rpsU NC_010519.1 965228 965443 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 965228..965443 Haemophilus somnus 2336 6108663 YP_001784174.1 CDS dnaG NC_010519.1 965604 967361 D synthesizes RNA primers at the replication forks; DNA primase 965604..967361 Haemophilus somnus 2336 6108664 YP_001784175.1 CDS HSM_0843 NC_010519.1 967428 969293 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 967428..969293 Haemophilus somnus 2336 6108665 YP_001784176.1 CDS HSM_0844 NC_010519.1 969941 979357 D PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1616 large adhesin; YadA domain-containing protein 969941..979357 Haemophilus somnus 2336 6108666 YP_001784177.1 CDS HSM_0845 NC_010519.1 979743 980369 D PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: hso:HS_1233 membrane protein; hypothetical protein 979743..980369 Haemophilus somnus 2336 6108667 YP_001784178.1 CDS glyQ NC_010519.1 980482 981393 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 980482..981393 Haemophilus somnus 2336 6108668 YP_001784179.1 CDS HSM_0847 NC_010519.1 981393 981662 D KEGG: hso:HS_1231 hypothetical protein; hypothetical protein 981393..981662 Haemophilus somnus 2336 6108669 YP_001784180.1 CDS HSM_0848 NC_010519.1 982522 982908 D hypothetical protein 982522..982908 Haemophilus somnus 2336 6108670 YP_001784181.1 CDS HSM_0849 NC_010519.1 983108 983362 D KEGG: hso:HS_1230 hypothetical protein; hypothetical protein 983108..983362 Haemophilus somnus 2336 6108671 YP_001784182.1 CDS HSM_0850 NC_010519.1 983526 984824 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(983526..984824) Haemophilus somnus 2336 6108672 YP_001784183.1 CDS HSM_0851 NC_010519.1 991488 992141 R KEGG: hso:HS_1709 transposase; transposase complement(991488..992141) Haemophilus somnus 2336 6108879 YP_001784184.1 CDS HSM_0852 NC_010519.1 992748 993020 D KEGG: hso:HS_1228 integrase; hypothetical protein 992748..993020 Haemophilus somnus 2336 6108675 YP_001784185.1 CDS HSM_0853 NC_010519.1 993239 994234 D KEGG: hso:HS_1227 hypothetical protein; hypothetical protein 993239..994234 Haemophilus somnus 2336 6108676 YP_001784186.1 CDS HSM_0854 NC_010519.1 994314 995345 D catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 994314..995345 Haemophilus somnus 2336 6108677 YP_001784187.1 CDS HSM_0855 NC_010519.1 995352 995828 D PFAM: flavin reductase domain protein FMN-binding; KEGG: hso:HS_1225 flavin:NADH reductase; flavin reductase domain-containing protein 995352..995828 Haemophilus somnus 2336 6108678 YP_001784188.1 CDS HSM_0856 NC_010519.1 995904 996848 R KEGG: rba:RB9243 hypothetical protein- glycosyltransferase; hypothetical protein complement(995904..996848) Haemophilus somnus 2336 6108679 YP_001784189.1 CDS aspS NC_010519.1 997098 998864 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(997098..998864) Haemophilus somnus 2336 6108680 YP_001784190.1 CDS HSM_0858 NC_010519.1 999010 999750 D TIGRFAM: methyltransferase; PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: hso:HS_1222 SAM-dependent methyltransferase; methyltransferase 999010..999750 Haemophilus somnus 2336 6108681 YP_001784191.1 CDS HSM_0859 NC_010519.1 999788 1000636 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(999788..1000636) Haemophilus somnus 2336 6108682 YP_001784192.1 CDS HSM_0860 NC_010519.1 1001039 1002094 R PFAM: phage integrase family protein; KEGG: ecp:ECP_0274 phage integrase; phage integrase family protein complement(1001039..1002094) Haemophilus somnus 2336 6108881 YP_001784193.1 CDS HSM_0861 NC_010519.1 1002329 1003426 R TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: hso:HS_1422 DNA-cytosine methyltransferase; DNA-cytosine methyltransferase complement(1002329..1003426) Haemophilus somnus 2336 6108685 YP_001784194.1 CDS HSM_0862 NC_010519.1 1003733 1004233 R KEGG: hdu:HD0960 hypothetical protein; hypothetical protein complement(1003733..1004233) Haemophilus somnus 2336 6108686 YP_001784195.1 CDS HSM_0863 NC_010519.1 1004294 1004722 R KEGG: hso:HS_1421 hypothetical protein; hypothetical protein complement(1004294..1004722) Haemophilus somnus 2336 6108687 YP_001784196.1 CDS HSM_0864 NC_010519.1 1005041 1005679 R KEGG: sit:TM1040_1688 hypothetical protein; hypothetical protein complement(1005041..1005679) Haemophilus somnus 2336 6108688 YP_001784197.1 CDS HSM_0865 NC_010519.1 1005832 1006158 R KEGG: hso:HS_1418 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(1005832..1006158) Haemophilus somnus 2336 6108689 YP_001784198.1 CDS HSM_0866 NC_010519.1 1006155 1006592 R KEGG: hso:HS_1417 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(1006155..1006592) Haemophilus somnus 2336 6108690 YP_001784199.1 CDS HSM_0867 NC_010519.1 1006589 1006873 R KEGG: hso:HS_1416 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(1006589..1006873) Haemophilus somnus 2336 6108691 YP_001784200.1 CDS HSM_0868 NC_010519.1 1006960 1007799 R KEGG: ecv:APECO1_4215 antirepressor protein; antirepressor protein complement(1006960..1007799) Haemophilus somnus 2336 6108692 YP_001784201.1 CDS HSM_0869 NC_010519.1 1008591 1009388 R KEGG: cjr:CJE1430 RloG protein; hypothetical protein complement(1008591..1009388) Haemophilus somnus 2336 6108693 YP_001784202.1 CDS HSM_0870 NC_010519.1 1009789 1009974 D hypothetical protein 1009789..1009974 Haemophilus somnus 2336 6108694 YP_001784203.1 CDS HSM_0871 NC_010519.1 1010153 1010518 D KEGG: ecp:ECP_4545 hypothetical protein; hypothetical protein 1010153..1010518 Haemophilus somnus 2336 6108696 YP_001784204.1 CDS HSM_0872 NC_010519.1 1010620 1011249 R KEGG: sgl:SG1183 hypothetical protein; hypothetical protein complement(1010620..1011249) Haemophilus somnus 2336 6108697 YP_001784205.1 CDS HSM_0873 NC_010519.1 1011246 1011908 R KEGG: bbr:BB3533 hypothetical protein; hypothetical protein complement(1011246..1011908) Haemophilus somnus 2336 6108698 YP_001784206.1 CDS HSM_0874 NC_010519.1 1011972 1012604 R PFAM: KilA domain protein; KEGG: vvu:VV2_0650 hypothetical protein; KilA domain-containing protein complement(1011972..1012604) Haemophilus somnus 2336 6108699 YP_001784207.1 CDS HSM_0875 NC_010519.1 1012882 1013709 R KEGG: xft:PD1061 DNA-damage-inducible protein D; hypothetical protein complement(1012882..1013709) Haemophilus somnus 2336 6108700 YP_001784208.1 CDS HSM_0876 NC_010519.1 1014768 1014989 R KEGG: hit:NTHI1717 hypothetical protein; hypothetical protein complement(1014768..1014989) Haemophilus somnus 2336 6108701 YP_001784209.1 CDS HSM_0877 NC_010519.1 1015001 1015189 D PFAM: protein of unknown function DUF1508; KEGG: deh:cbdb_A1247 hypothetical protein; hypothetical protein 1015001..1015189 Haemophilus somnus 2336 6108702 YP_001784210.1 CDS HSM_0878 NC_010519.1 1015606 1015902 D TIGRFAM: Addiction module killer protein HI1419; PFAM: protein of unknown function DUF891; KEGG: hin:HI1419 hypothetical protein; addiction module killer protein 1015606..1015902 Haemophilus somnus 2336 6108703 YP_001784211.1 CDS HSM_0879 NC_010519.1 1015904 1016200 D TIGRFAM: Addiction module antidote protein HI1420; PFAM: helix-turn-helix domain protein; KEGG: hin:HI1420 hypothetical protein; transcriptional regulator 1015904..1016200 Haemophilus somnus 2336 6108704 YP_001784212.1 CDS HSM_0880 NC_010519.1 1016228 1017232 R KEGG: bam:Bamb_0901 hypothetical protein; hypothetical protein complement(1016228..1017232) Haemophilus somnus 2336 6108705 YP_001784213.1 CDS HSM_0881 NC_010519.1 1017329 1018015 R PFAM: peptidase S24 S26A and S26B; SMART: helix-turn-helix domain protein; KEGG: bbr:BB1678 phage repressor; prophage repressor complement(1017329..1018015) Haemophilus somnus 2336 6108707 YP_001784214.1 CDS HSM_0882 NC_010519.1 1018118 1018345 D KEGG: ecs:ECs1942 regulatory protein; regulatory protein 1018118..1018345 Haemophilus somnus 2336 6108708 YP_001784215.1 CDS HSM_0883 NC_010519.1 1018498 1018737 D KEGG: hso:HS_1403 hypothetical protein; hypothetical protein 1018498..1018737 Haemophilus somnus 2336 6108709 YP_001784216.1 CDS HSM_0884 NC_010519.1 1018727 1019551 D KEGG: hso:HS_1402 hypothetical protein; hypothetical protein 1018727..1019551 Haemophilus somnus 2336 6108710 YP_001784217.1 CDS HSM_0885 NC_010519.1 1019548 1020240 D PFAM: replication P family protein; KEGG: hso:HS_1401 replication protein P; replication P family protein 1019548..1020240 Haemophilus somnus 2336 6108711 YP_001784218.1 CDS HSM_0886 NC_010519.1 1020255 1020788 D TIGRFAM: phage N-6-adenine-methyltransferase; PFAM: DNA N-6-adenine-methyltransferase; KEGG: hso:HS_1400 DNA methylase; phage N-6-adenine-methyltransferase 1020255..1020788 Haemophilus somnus 2336 6108712 YP_001784219.1 CDS HSM_0887 NC_010519.1 1020801 1021253 D KEGG: hso:HS_1399 hypothetical protein; hypothetical protein 1020801..1021253 Haemophilus somnus 2336 6108713 YP_001784220.1 CDS HSM_0888 NC_010519.1 1021305 1021919 R PFAM: BRO domain protein; KEGG: hso:HS_1398 prophage antirepressor; prophage antirepressor complement(1021305..1021919) Haemophilus somnus 2336 6108714 YP_001784221.1 CDS HSM_0889 NC_010519.1 1022474 1022887 R PFAM: protein of unknown function UPF0150; KEGG: hso:HS_1396 hypothetical protein; hypothetical protein complement(1022474..1022887) Haemophilus somnus 2336 6108715 YP_001784222.1 CDS HSM_0890 NC_010519.1 1022910 1023125 R PFAM: YcfA family protein; KEGG: hso:HS_1395 hypothetical protein; hypothetical protein complement(1022910..1023125) Haemophilus somnus 2336 6108716 YP_001784223.1 CDS HSM_0891 NC_010519.1 1023286 1023864 D PFAM: bacteriophage Lambda NinG family protein; KEGG: hso:HS_1394 NinG recombination protein; bacteriophage lambda NinG family protein 1023286..1023864 Haemophilus somnus 2336 6108718 YP_001784224.1 CDS HSM_0892 NC_010519.1 1024492 1024896 R KEGG: nmc:NMC0837 hypothetical protein; hypothetical protein complement(1024492..1024896) Haemophilus somnus 2336 6108719 YP_001784225.1 CDS HSM_0893 NC_010519.1 1025178 1025414 D KEGG: hso:HS_1389 Haemophilus-specific protein, uncharacterized; hypothetical protein 1025178..1025414 Haemophilus somnus 2336 6108720 YP_001784226.1 CDS HSM_0894 NC_010519.1 1025404 1025943 D PFAM: glycoside hydrolase family 24; KEGG: hso:HS_1388 lysozyme, phage-related lysozyme; glycoside hydrolase family protein 1025404..1025943 Haemophilus somnus 2336 6108721 YP_001784227.1 CDS HSM_0895 NC_010519.1 1025916 1026245 D KEGG: hso:HS_1387 hypothetical protein; hypothetical protein 1025916..1026245 Haemophilus somnus 2336 6108722 YP_001784228.1 CDS HSM_0896 NC_010519.1 1026442 1027137 D KEGG: hso:HS_1386 terminase small subunit; terminase small subunit 1026442..1027137 Haemophilus somnus 2336 6108723 YP_001784229.1 CDS HSM_0897 NC_010519.1 1027137 1028684 D KEGG: hso:HS_1385 hypothetical protein; hypothetical protein 1027137..1028684 Haemophilus somnus 2336 6108724 YP_001784230.1 CDS HSM_0898 NC_010519.1 1028686 1030863 D KEGG: hso:HS_1384 Haemophilus-specific protein, uncharacterized; hypothetical protein 1028686..1030863 Haemophilus somnus 2336 6108725 YP_001784231.1 CDS HSM_0899 NC_010519.1 1031022 1031120 D hypothetical protein 1031022..1031120 Haemophilus somnus 2336 6108726 YP_001784232.1 CDS HSM_0900 NC_010519.1 1031495 1031683 D KEGG: hso:HS_1382 phage-related protein; hypothetical protein 1031495..1031683 Haemophilus somnus 2336 6108727 YP_001784233.1 CDS HSM_0901 NC_010519.1 1032458 1033333 D KEGG: ecv:APECO1_4215 antirepressor protein; antirepressor protein 1032458..1033333 Haemophilus somnus 2336 6108730 YP_001784234.1 CDS HSM_0902 NC_010519.1 1033403 1036102 D KEGG: hso:HS_1381 hypothetical protein; hypothetical protein 1033403..1036102 Haemophilus somnus 2336 6108731 YP_001784235.1 CDS HSM_0903 NC_010519.1 1036104 1040183 D KEGG: hso:HS_1381 hypothetical protein; hypothetical protein 1036104..1040183 Haemophilus somnus 2336 6108732 YP_001784236.1 CDS HSM_0904 NC_010519.1 1040446 1040748 D KEGG: hso:HS_1380 transcription regulator; XRE family transcriptional regulator 1040446..1040748 Haemophilus somnus 2336 6108733 YP_001784237.1 CDS HSM_0905 NC_010519.1 1040833 1041027 D KEGG: hso:HS_1379 Haemophilus-specific protein, uncharacterized; hypothetical protein 1040833..1041027 Haemophilus somnus 2336 6108734 YP_001784238.1 CDS HSM_0906 NC_010519.1 1041105 1041968 D KEGG: hso:HS_1378 hypothetical protein; hypothetical protein 1041105..1041968 Haemophilus somnus 2336 6108735 YP_001784239.1 CDS HSM_0907 NC_010519.1 1041994 1042989 D KEGG: hso:HS_1377 hypothetical protein; hypothetical protein 1041994..1042989 Haemophilus somnus 2336 6108736 YP_001784240.1 CDS HSM_0908 NC_010519.1 1043051 1043497 D KEGG: hso:HS_1376 Haemophilus-specific protein, uncharacterized; hypothetical protein 1043051..1043497 Haemophilus somnus 2336 6108737 YP_001784241.1 CDS HSM_0909 NC_010519.1 1043494 1043883 D KEGG: hso:HS_1375 Haemophilus-specific protein, uncharacterized; hypothetical protein 1043494..1043883 Haemophilus somnus 2336 6108738 YP_001784242.1 CDS HSM_0910 NC_010519.1 1044147 1046126 D KEGG: hso:HS_1373 Haemophilus-specific protein, uncharacterized; hypothetical protein 1044147..1046126 Haemophilus somnus 2336 6108739 YP_001784243.1 CDS HSM_0911 NC_010519.1 1046119 1047498 D KEGG: hso:HS_1372 phage-related tail fiber protein; hypothetical protein 1046119..1047498 Haemophilus somnus 2336 6108741 YP_001784244.1 CDS HSM_0912 NC_010519.1 1047495 1047842 R PFAM: helix-turn-helix domain protein; KEGG: xfa:XF0534 hypothetical protein; XRE family transcriptional regulator complement(1047495..1047842) Haemophilus somnus 2336 6108742 YP_001784245.1 CDS HSM_0913 NC_010519.1 1047826 1048077 R KEGG: tde:TDE1648 hypothetical protein; hypothetical protein complement(1047826..1048077) Haemophilus somnus 2336 6108743 YP_001784246.1 CDS HSM_0914 NC_010519.1 1048140 1048766 D KEGG: nme:NMB1119 hypothetical protein; hypothetical protein 1048140..1048766 Haemophilus somnus 2336 6108744 YP_001784247.1 CDS HSM_0915 NC_010519.1 1048759 1049028 D KEGG: hso:HS_1370 hypothetical protein; hypothetical protein 1048759..1049028 Haemophilus somnus 2336 6108745 YP_001784248.1 CDS HSM_0916 NC_010519.1 1049156 1049800 D KEGG: hso:HS_1369 hypothetical protein; hypothetical protein 1049156..1049800 Haemophilus somnus 2336 6108746 YP_001784249.1 CDS HSM_0917 NC_010519.1 1049797 1050114 D KEGG: hso:HS_1368 Haemophilus-specific protein, uncharacterized; hypothetical protein 1049797..1050114 Haemophilus somnus 2336 6108747 YP_001784250.1 CDS HSM_0918 NC_010519.1 1050117 1051313 D KEGG: hso:HS_1367 Haemophilus-specific protein, uncharacterized; hypothetical protein 1050117..1051313 Haemophilus somnus 2336 6108748 YP_001784251.1 CDS HSM_0919 NC_010519.1 1051332 1051865 D KEGG: hso:HS_1366 Haemophilus-specific protein, uncharacterized; hypothetical protein 1051332..1051865 Haemophilus somnus 2336 6108749 YP_001784252.1 CDS HSM_0920 NC_010519.1 1051865 1052491 D KEGG: hso:HS_1365 Haemophilus-specific protein, uncharacterized; hypothetical protein 1051865..1052491 Haemophilus somnus 2336 6108750 YP_001784253.1 CDS HSM_0921 NC_010519.1 1053004 1053252 D PFAM: phage virion morphogenesis ( tail completion) protein; KEGG: hit:NTHI1873 probable bacteriophage tail completion protein gpS homolog; phage virion morphogenesis ( tail completion) protein 1053004..1053252 Haemophilus somnus 2336 6108752 YP_001784254.1 CDS HSM_0922 NC_010519.1 1053507 1053884 R hypothetical protein complement(1053507..1053884) Haemophilus somnus 2336 6108753 YP_001784255.1 CDS HSM_0923 NC_010519.1 1053982 1054251 R KEGG: hin:HI1501 hypothetical protein HI1501; hypothetical protein complement(1053982..1054251) Haemophilus somnus 2336 6108754 YP_001784256.1 CDS HSM_0924 NC_010519.1 1054309 1055247 R acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1054309..1055247) Haemophilus somnus 2336 6108755 YP_001784257.1 CDS HSM_0925 NC_010519.1 1055370 1056800 D catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 1055370..1056800 Haemophilus somnus 2336 6108756 YP_001784258.1 CDS HSM_0926 NC_010519.1 1056810 1057154 D PFAM: arsenate reductase; KEGG: hso:HS_0577 arsenate reductase; arsenate reductase 1056810..1057154 Haemophilus somnus 2336 6108757 YP_001784259.1 CDS HSM_0927 NC_010519.1 1057267 1058400 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 1057267..1058400 Haemophilus somnus 2336 6108758 YP_001784260.1 CDS HSM_0928 NC_010519.1 1058390 1059070 D PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: hso:HS_0579 D-alanyl-D-alanine carboxypeptidase-related protein; peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin 1058390..1059070 Haemophilus somnus 2336 6108759 YP_001784261.1 CDS HSM_0929 NC_010519.1 1059123 1059743 D PFAM: NUDIX hydrolase; KEGG: hso:HS_0580 ADP-ribose diphosphatase; ADP-ribose diphosphatase 1059123..1059743 Haemophilus somnus 2336 6108760 YP_001784262.1 CDS HSM_0930 NC_010519.1 1059882 1060712 D PFAM: metallophosphoesterase; Calcineurin phosphoesterase domain protein; KEGG: hso:HS_0581 3',5'-cyclic-nucleotide phosphodiesterase; cyclic 3',5'-adenosine monophosphate phosphodiesterase 1059882..1060712 Haemophilus somnus 2336 6108761 YP_001784263.1 CDS HSM_0931 NC_010519.1 1060790 1062568 R PFAM: TonB-dependent receptor; KEGG: hso:HS_0582 transferrin binding protein A; TonB-dependent receptor complement(1060790..1062568) Haemophilus somnus 2336 6108763 YP_001784264.1 CDS HSM_0932 NC_010519.1 1062508 1063182 R PFAM: TonB-dependent receptor plug; KEGG: hso:HS_0582 transferrin binding protein A; TonB-dependent receptor plug complement(1062508..1063182) Haemophilus somnus 2336 6108764 YP_001784265.1 CDS HSM_0933 NC_010519.1 1063308 1064435 R PFAM: inner-membrane translocator; KEGG: hso:HS_0584 D-xylose ABC transporter permease; monosaccharide-transporting ATPase complement(1063308..1064435) Haemophilus somnus 2336 6108765 YP_001784266.1 CDS HSM_0934 NC_010519.1 1064439 1065953 R with XylFH is part of the high affinity xylose ABC transporter; xylose ABC transporter ATP-binding protein complement(1064439..1065953) Haemophilus somnus 2336 6108766 YP_001784267.1 CDS xylF NC_010519.1 1066013 1067014 R periplasmic substrate-binding component of the ATP-dependent xylose transporter; high affinity; sugar ABC transporter substrate-binding protein complement(1066013..1067014) Haemophilus somnus 2336 6108767 YP_001784268.1 CDS HSM_0936 NC_010519.1 1067268 1068587 D catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 1067268..1068587 Haemophilus somnus 2336 6108768 YP_001784269.1 CDS HSM_0937 NC_010519.1 1068656 1070116 D TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_0588 xylulokinase (xylulose kinase); xylulokinase 1068656..1070116 Haemophilus somnus 2336 6108769 YP_001784270.1 CDS HSM_0938 NC_010519.1 1070247 1071413 R PFAM: Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0602 adhesin; hemagluttinin domain-containing protein complement(1070247..1071413) Haemophilus somnus 2336 6108770 YP_001784271.1 CDS HSM_0939 NC_010519.1 1071701 1072495 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0590 peptide ABC transporter ATP-binding protein; ABC transporter complement(1071701..1072495) Haemophilus somnus 2336 6108771 YP_001784272.1 CDS HSM_0940 NC_010519.1 1072511 1073557 R TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; KEGG: hso:HS_0591 peptide ABC transporter ATP-binding protein; oligopeptide/dipeptide ABC transporter ATPase complement(1072511..1073557) Haemophilus somnus 2336 6108772 YP_001784273.1 CDS HSM_0941 NC_010519.1 1073569 1074456 R PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0592 peptide ABC transporter permease; binding-protein-dependent transporters inner membrane component complement(1073569..1074456) Haemophilus somnus 2336 6108774 YP_001784274.1 CDS HSM_0942 NC_010519.1 1074446 1075411 R PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0593 peptide ABC transporter permease; binding-protein-dependent transporters inner membrane component complement(1074446..1075411) Haemophilus somnus 2336 6108775 YP_001784275.1 CDS HSM_0943 NC_010519.1 1075439 1077127 R PFAM: extracellular solute-binding protein family 5; KEGG: hso:HS_0594 peptide ABC transporter periplasmic-binding protein; 4-phytase complement(1075439..1077127) Haemophilus somnus 2336 6108776 YP_001784276.1 CDS HSM_0944 NC_010519.1 1077194 1078603 D PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: hso:HS_0595 conserved hypothetical protein; hypothetical protein 1077194..1078603 Haemophilus somnus 2336 6108777 YP_001784277.1 CDS HSM_0945 NC_010519.1 1078613 1079686 D PFAM: conserved hypothetical protein 1620; KEGG: hso:HS_0596 hypothetical protein; hypothetical protein 1078613..1079686 Haemophilus somnus 2336 6108778 YP_001784278.1 CDS grxA NC_010519.1 1079793 1080056 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin complement(1079793..1080056) Haemophilus somnus 2336 6108779 YP_001784279.1 CDS HSM_0947 NC_010519.1 1080177 1082420 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(1080177..1082420) Haemophilus somnus 2336 6108780 YP_001784280.1 CDS HSM_0948 NC_010519.1 1082466 1083587 R KEGG: nmc:NMC0772 type II restriction endonuclease; type II restriction endonuclease complement(1082466..1083587) Haemophilus somnus 2336 6108781 YP_001784281.1 CDS HSM_0949 NC_010519.1 1083592 1084818 R TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: nmc:NMC0771 modification methylase; DNA-cytosine methyltransferase complement(1083592..1084818) Haemophilus somnus 2336 6108782 YP_001784282.1 CDS HSM_0950 NC_010519.1 1084869 1086761 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(1084869..1086761) Haemophilus somnus 2336 6108783 YP_001784283.1 CDS HSM_0951 NC_010519.1 1086817 1088103 R TIGRFAM: AmpG-related permease; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_0600 AmpG protein; AmpG-like permease complement(1086817..1088103) Haemophilus somnus 2336 6108785 YP_001784284.1 CDS HSM_0952 NC_010519.1 1088285 1089598 D PFAM: xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: hso:HS_0601 conserved permease, xanthine/uracil family; xanthine/uracil/vitamin C permease 1088285..1089598 Haemophilus somnus 2336 6108786 YP_001784285.1 CDS HSM_0953 NC_010519.1 1089705 1090931 R PFAM: Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0602 adhesin; hemagluttinin domain-containing protein complement(1089705..1090931) Haemophilus somnus 2336 6108787 YP_001784286.1 CDS HSM_0954 NC_010519.1 1091496 1092254 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(1091496..1092254) Haemophilus somnus 2336 6108883 YP_001784287.1 CDS rnhA NC_010519.1 1092325 1092789 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 1092325..1092789 Haemophilus somnus 2336 6108789 YP_001784288.1 CDS HSM_0956 NC_010519.1 1092864 1094069 R TIGRFAM: mannose-6-phosphate isomerase, class I; KEGG: hso:HS_0605 mannose-6-phosphate isomerase (phosphomannose isomerase); mannose-6-phosphate isomerase complement(1092864..1094069) Haemophilus somnus 2336 6108790 YP_001784289.1 CDS HSM_0957 NC_010519.1 1094066 1094545 R KEGG: hso:HS_0606 hypothetical protein; hypothetical protein complement(1094066..1094545) Haemophilus somnus 2336 6108791 YP_001784290.1 CDS HSM_0958 NC_010519.1 1094603 1095439 R hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID complement(1094603..1095439) Haemophilus somnus 2336 6108792 YP_001784291.1 CDS HSM_0959 NC_010519.1 1095454 1096254 R TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; KEGG: hso:HS_0608 protein-N(pi)-phosphohistidine-sugar phosphotransferase (mannose-specific phosphotransferase system IIC component); PTS system mannose/fructose/sorbose family transporter subunit IIC complement(1095454..1096254) Haemophilus somnus 2336 6108793 YP_001784292.1 CDS HSM_0960 NC_010519.1 1096266 1097237 R TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PTS system, mannose/fructose/sorbose family, IIsubunit alpha; KEGG: hso:HS_0609 protein-N(pi)-phosphohistidine-sugar phosphotransferase (phosphotransferase system mannose/fructose-specific IIA component); PTS system mannose/fructose/sorbose family subunit IIB complement(1096266..1097237) Haemophilus somnus 2336 6108794 YP_001784293.1 CDS HSM_0961 NC_010519.1 1097447 1097809 R PFAM: protein of unknown function DUF496; KEGG: hso:HS_0610 hypothetical protein; hypothetical protein complement(1097447..1097809) Haemophilus somnus 2336 6108796 YP_001784294.1 CDS HSM_0962 NC_010519.1 1097999 1099078 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1097999..1099078 Haemophilus somnus 2336 6108797 YP_001784295.1 CDS HSM_0963 NC_010519.1 1099137 1100246 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1099137..1100246 Haemophilus somnus 2336 6108798 YP_001784296.1 CDS HSM_0964 NC_010519.1 1100309 1101607 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1100309..1101607 Haemophilus somnus 2336 6108799 YP_001784297.1 CDS HSM_0965 NC_010519.1 1101843 1103057 D TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: hso:HS_0614 membrane fusion protein; RND family efflux transporter MFP subunit 1101843..1103057 Haemophilus somnus 2336 6108800 YP_001784298.1 CDS HSM_0966 NC_010519.1 1103079 1106195 D PFAM: acriflavin resistance protein; KEGG: hso:HS_0615 cation/multidrug efflux protein; acriflavin resistance protein 1103079..1106195 Haemophilus somnus 2336 6108801 YP_001784299.1 CDS HSM_0967 NC_010519.1 1106221 1106979 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB complement(1106221..1106979) Haemophilus somnus 2336 6108802 YP_001784300.1 CDS HSM_0968 NC_010519.1 1106992 1108698 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(1106992..1108698) Haemophilus somnus 2336 6108803 YP_001784301.1 CDS HSM_0969 NC_010519.1 1108704 1110011 R TIGRFAM: isochorismate synthase; PFAM: anthranilate synthase component I and chorismate binding protein; KEGG: hso:HS_0618 isochorismate synthase; isochorismate synthase complement(1108704..1110011) Haemophilus somnus 2336 6108804 YP_001784302.1 CDS HSM_0970 NC_010519.1 1110139 1111353 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 1110139..1111353 Haemophilus somnus 2336 6108805 YP_001784303.1 CDS HSM_0971 NC_010519.1 1111398 1112138 R Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator complement(1111398..1112138) Haemophilus somnus 2336 6108807 YP_001784304.1 CDS HSM_0972 NC_010519.1 1112308 1112841 D disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1112308..1112841 Haemophilus somnus 2336 6108808 YP_001784305.1 CDS HSM_0975 NC_010519.1 1114012 1114707 R KEGG: pmu:PM1140 glycosyl transferase; glycosyl transferase family protein complement(1114012..1114707) Haemophilus somnus 2336 6108810 YP_001784306.1 CDS HSM_0976 NC_010519.1 1114845 1115036 R KEGG: hdu:HD0466 lipooligosaccharide N-acetylglucosamine glycosyltransferase; cell wall biogenesis glycosyltransferase-like protein complement(1114845..1115036) Haemophilus somnus 2336 6108811 YP_001784307.1 CDS HSM_0977 NC_010519.1 1115051 1115884 R PFAM: glycosyl transferase family 25; KEGG: hit:NTHI0677 UDP-Gal--lipooligosaccharide galactosyltransferase; glycosyl transferase family protein complement(1115051..1115884) Haemophilus somnus 2336 6108812 YP_001784308.1 CDS HSM_0978 NC_010519.1 1115946 1116761 R PFAM: glycosyl transferase family 25; KEGG: hdu:HD0472 lipooligosaccharide galactosyltransferase II; glycosyl transferase family protein complement(1115946..1116761) Haemophilus somnus 2336 6108813 YP_001784309.1 CDS HSM_0979 NC_010519.1 1116883 1117764 D PFAM: glycosyl transferase family 25; KEGG: hso:HS_0638 Lob1 protein; glycosyl transferase family protein 1116883..1117764 Haemophilus somnus 2336 6108814 YP_001784310.1 CDS fbpC NC_010519.1 1117902 1118951 R Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding subunit complement(1117902..1118951) Haemophilus somnus 2336 6108815 YP_001784311.1 CDS HSM_0981 NC_010519.1 1119018 1121075 R PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0640 Fe3+ ABC transporter permease; binding-protein-dependent transporters inner membrane component complement(1119018..1121075) Haemophilus somnus 2336 6108817 YP_001784312.1 CDS HSM_0982 NC_010519.1 1121097 1122128 R PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_0641 Fe3+ ABC transporter iron-binding protein; extracellular solute-binding protein complement(1121097..1122128) Haemophilus somnus 2336 6108818 YP_001784313.1 CDS HSM_0983 NC_010519.1 1122156 1123196 R PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_0643 Fe3+ ABC transporter iron-binding protein; extracellular solute-binding protein complement(1122156..1123196) Haemophilus somnus 2336 6108819 YP_001784314.1 CDS HSM_0984 NC_010519.1 1123400 1124041 D functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1123400..1124041 Haemophilus somnus 2336 6108820 YP_001784315.1 CDS dcd NC_010519.1 1124051 1124635 D Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 1124051..1124635 Haemophilus somnus 2336 6108821 YP_001784316.1 CDS HSM_0986 NC_010519.1 1124650 1125843 D KEGG: hso:HS_0646 hypothetical protein; hypothetical protein 1124650..1125843 Haemophilus somnus 2336 6108822 YP_001784317.1 CDS HSM_0987 NC_010519.1 1126121 1127122 D PFAM: sodium symporter; KEGG: hso:HS_0647 sodium-dependent transporter; bile acid:sodium symporter 1126121..1127122 Haemophilus somnus 2336 6108823 YP_001784318.1 CDS adk NC_010519.1 1127212 1127856 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1127212..1127856 Haemophilus somnus 2336 6108824 YP_001784319.1 CDS HSM_0989 NC_010519.1 1127942 1128529 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(1127942..1128529) Haemophilus somnus 2336 6108825 YP_001784320.1 CDS ppnK NC_010519.1 1128672 1129589 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1128672..1129589 Haemophilus somnus 2336 6108826 YP_001784321.1 CDS HSM_0991 NC_010519.1 1129667 1131346 D TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: hso:HS_0651 DNA repair protein; DNA repair protein RecN 1129667..1131346 Haemophilus somnus 2336 6108828 YP_001784322.1 CDS HSM_0992 NC_010519.1 1131537 1132847 R PFAM: sodium/hydrogen exchanger; KEGG: hso:HS_0652 Na+/H+ antiporter; sodium/hydrogen exchanger complement(1131537..1132847) Haemophilus somnus 2336 6108829 YP_001784323.1 CDS HSM_0993 NC_010519.1 1133175 1133525 R PFAM: endoribonuclease L-PSP; KEGG: hso:HS_0653 translation inhibitor of mRNA; endoribonuclease L-PSP complement(1133175..1133525) Haemophilus somnus 2336 6108830 YP_001784324.1 CDS HSM_0994 NC_010519.1 1133636 1134358 D KEGG: hso:HS_0654 hypothetical protein; hypothetical protein 1133636..1134358 Haemophilus somnus 2336 6108831 YP_001784325.1 CDS HSM_0995 NC_010519.1 1134373 1135272 D TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; KEGG: hso:HS_0655 ribosomal protein S6 modification protein; alpha-L-glutamate ligase 1134373..1135272 Haemophilus somnus 2336 6108832 YP_001784326.1 CDS lpxK NC_010519.1 1135391 1136386 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1135391..1136386 Haemophilus somnus 2336 6108833 YP_001784327.1 CDS HSM_0997 NC_010519.1 1136383 1136580 D PFAM: protein of unknown function DUF343; KEGG: hso:HS_0657 hypothetical protein; hypothetical protein 1136383..1136580 Haemophilus somnus 2336 6108834 YP_001784328.1 CDS HSM_0998 NC_010519.1 1136595 1137365 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1136595..1137365 Haemophilus somnus 2336 6108835 YP_001784329.1 CDS uvrC NC_010519.1 1137358 1139187 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1137358..1139187 Haemophilus somnus 2336 6108836 YP_001784330.1 CDS HSM_1000 NC_010519.1 1139253 1139639 R PFAM: hypothetical protein?; KEGG: hso:HS_0660 membrane protein; TM2 domain-containing protein complement(1139253..1139639) Haemophilus somnus 2336 6108837 YP_001784331.1 CDS HSM_1001 NC_010519.1 1139764 1141743 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1139764..1141743) Haemophilus somnus 2336 6106842 YP_001784332.1 CDS HSM_1002 NC_010519.1 1141808 1142596 R PFAM: short-chain dehydrogenase/reductase SDR; KEGG: hso:HS_0662 enoyl-[acyl-carrier-protein] reductase (NADH); short-chain dehydrogenase/reductase SDR complement(1141808..1142596) Haemophilus somnus 2336 6106843 YP_001784333.1 CDS HSM_1003 NC_010519.1 1142687 1143454 R PFAM: protein of unknown function DUF34; KEGG: hso:HS_0663 hypothetical protein; hypothetical protein complement(1142687..1143454) Haemophilus somnus 2336 6106844 YP_001784334.1 CDS mnmC NC_010519.1 1143466 1145496 R catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase complement(1143466..1145496) Haemophilus somnus 2336 6106845 YP_001784335.1 CDS HSM_1005 NC_010519.1 1145651 1146871 D FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1145651..1146871 Haemophilus somnus 2336 6106846 YP_001784336.1 CDS HSM_1006 NC_010519.1 1147290 1148618 D TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: hso:HS_1101 ammonium transporter; ammonium transporter 1147290..1148618 Haemophilus somnus 2336 6106847 YP_001784337.1 CDS HSM_1007 NC_010519.1 1149663 1150217 R 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease complement(1149663..1150217) Haemophilus somnus 2336 6108884 YP_001784338.1 CDS HSM_1008 NC_010519.1 1150287 1151339 D EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 1150287..1151339 Haemophilus somnus 2336 6106849 YP_001784339.1 CDS HSM_1009 NC_010519.1 1151562 1151819 D TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: hso:HS_1098 phosphocarrier protein HPr; phosphotransferase system, phosphocarrier protein HPr 1151562..1151819 Haemophilus somnus 2336 6106850 YP_001784340.1 CDS HSM_1010 NC_010519.1 1151924 1153651 D phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transporter; phosphoenolpyruvate-protein phosphotransferase 1151924..1153651 Haemophilus somnus 2336 6106851 YP_001784341.1 CDS HSM_1011 NC_010519.1 1153714 1154214 D functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 1153714..1154214 Haemophilus somnus 2336 6106853 YP_001784342.1 CDS aceE NC_010519.1 1154509 1157172 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 1154509..1157172 Haemophilus somnus 2336 6106854 YP_001784343.1 CDS HSM_1013 NC_010519.1 1157227 1159113 D TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: hso:HS_1094 pyruvate dehydrogenase, E2 complex; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 1157227..1159113 Haemophilus somnus 2336 6106855 YP_001784344.1 CDS HSM_1014 NC_010519.1 1159197 1160621 D E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1159197..1160621 Haemophilus somnus 2336 6106856 YP_001784345.1 CDS HSM_1015 NC_010519.1 1160710 1161162 R KEGG: hso:HS_1092 ImpA protein; ImpA protein complement(1160710..1161162) Haemophilus somnus 2336 6106857 YP_001784346.1 CDS HSM_1016 NC_010519.1 1161421 1162662 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 1161421..1162662 Haemophilus somnus 2336 6106858 YP_001784347.1 CDS HSM_1017 NC_010519.1 1162976 1163296 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 1162976..1163296 Haemophilus somnus 2336 6106859 YP_001784348.1 CDS tsf NC_010519.1 1163470 1164321 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(1163470..1164321) Haemophilus somnus 2336 6106860 YP_001784349.1 CDS rpsB NC_010519.1 1164444 1165163 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(1164444..1165163) Haemophilus somnus 2336 6106861 YP_001784350.1 CDS HSM_1020 NC_010519.1 1165418 1167274 R PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: hso:HS_1087 peptidyl-prolyl cis-trans isomerase D; PpiC-type peptidyl-prolyl cis-trans isomerase complement(1165418..1167274) Haemophilus somnus 2336 6106862 YP_001784351.1 CDS HSM_1021 NC_010519.1 1167566 1169005 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(1167566..1169005) Haemophilus somnus 2336 6106864 YP_001784352.1 CDS HSM_1022 NC_010519.1 1169291 1180540 R PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1085 large adhesin; YadA domain-containing protein complement(1169291..1180540) Haemophilus somnus 2336 6106865 YP_001784353.1 CDS HSM_1023 NC_010519.1 1181063 1181629 R TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: hso:HS_1153 phosphatidylglycerophosphate synthase; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(1181063..1181629) Haemophilus somnus 2336 6106866 YP_001784354.1 CDS HSM_1024 NC_010519.1 1181720 1182592 R PFAM: protein of unknown function DUF455; KEGG: hso:HS_1152 hypothetical protein; hypothetical protein complement(1181720..1182592) Haemophilus somnus 2336 6106867 YP_001784355.1 CDS HSM_1025 NC_010519.1 1182884 1183225 R TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase; KEGG: hso:HS_1151 hypothetical protein; alkylhydroperoxidase complement(1182884..1183225) Haemophilus somnus 2336 6108885 YP_001784356.1 CDS HSM_1026 NC_010519.1 1183330 1185060 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(1183330..1185060) Haemophilus somnus 2336 6106869 YP_001784357.1 CDS HSM_1027 NC_010519.1 1185060 1186823 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(1185060..1186823) Haemophilus somnus 2336 6106870 YP_001784358.1 CDS HSM_1028 NC_010519.1 1186889 1187842 R TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: hso:HS_1148 thioredoxin reductase; thioredoxin reductase complement(1186889..1187842) Haemophilus somnus 2336 6106871 YP_001784359.1 CDS pflA NC_010519.1 1187971 1188711 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(1187971..1188711) Haemophilus somnus 2336 6106872 YP_001784360.1 CDS HSM_1030 NC_010519.1 1188976 1189929 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 1188976..1189929 Haemophilus somnus 2336 6106873 YP_001784361.1 CDS HSM_1031 NC_010519.1 1189943 1191208 D PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; KEGG: hso:HS_1145 tagatose 6-phosphate kinase; tagatose-6-phosphate kinase 1189943..1191208 Haemophilus somnus 2336 6106875 YP_001784362.1 CDS HSM_1032 NC_010519.1 1191221 1191667 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA 1191221..1191667 Haemophilus somnus 2336 6106876 YP_001784363.1 CDS HSM_1033 NC_010519.1 1191691 1191975 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB 1191691..1191975 Haemophilus somnus 2336 6106877 YP_001784364.1 CDS HSM_1034 NC_010519.1 1191980 1193338 D TIGRFAM: PTS system, galactitol-specific IIC subunit; PFAM: PTS system Galactitol-specific IIC component; KEGG: hso:HS_1142 PTS system, galactitol-specific IIC component; PTS system galactitol-specific transporter subunit IIC 1191980..1193338 Haemophilus somnus 2336 6106878 YP_001784365.1 CDS HSM_1035 NC_010519.1 1193352 1194395 D Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 1193352..1194395 Haemophilus somnus 2336 6106879 YP_001784366.1 CDS HSM_1036 NC_010519.1 1194450 1195280 D PFAM: regulatory protein GntR HTH; regulatory protein DeoR; hypothetical protein; regulatory protein DeoR; KEGG: hso:HS_1140 galactitol utilization operon repressor; DeoR family transcriptional regulator 1194450..1195280 Haemophilus somnus 2336 6106880 YP_001784367.1 CDS HSM_1037 NC_010519.1 1195530 1196246 R KEGG: hso:HS_1139 hypothetical protein; hypothetical protein complement(1195530..1196246) Haemophilus somnus 2336 6106881 YP_001784368.1 CDS HSM_1038 NC_010519.1 1196231 1197151 R PFAM: protein of unknown function DUF692; Xylose isomerase domain protein TIM barrel; KEGG: hso:HS_1138 hypothetical protein; hypothetical protein complement(1196231..1197151) Haemophilus somnus 2336 6106882 YP_001784369.1 CDS HSM_1039 NC_010519.1 1197197 1197430 R KEGG: pmu:PM0212 hypothetical HI1601; hypothetical protein complement(1197197..1197430) Haemophilus somnus 2336 6106883 YP_001784370.1 CDS HSM_1040 NC_010519.1 1197453 1197911 R PFAM: DoxX family protein; KEGG: hso:HS_1137 hypothetical protein; DoxX family protein complement(1197453..1197911) Haemophilus somnus 2336 6106884 YP_001784371.1 CDS HSM_1041 NC_010519.1 1198046 1200370 R TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL; KEGG: hso:HS_1136 formate acetyltransferase; formate acetyltransferase complement(1198046..1200370) Haemophilus somnus 2336 6106886 YP_001784372.1 CDS HSM_1042 NC_010519.1 1200465 1201316 R PFAM: formate/nitrite transporter; KEGG: hso:HS_1135 formate transporter; formate/nitrite transporter complement(1200465..1201316) Haemophilus somnus 2336 6106887 YP_001784373.1 CDS HSM_1043 NC_010519.1 1201560 1201910 D PFAM: histidine triad (HIT) protein; KEGG: hso:HS_1134 HIT-like protein; histidine triad (HIT) protein 1201560..1201910 Haemophilus somnus 2336 6106888 YP_001784374.1 CDS HSM_1044 NC_010519.1 1201910 1202266 D KEGG: hso:HS_1133 hypothetical protein; hypothetical protein 1201910..1202266 Haemophilus somnus 2336 6106889 YP_001784375.1 CDS HSM_1045 NC_010519.1 1202273 1203319 D hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1202273..1203319 Haemophilus somnus 2336 6106890 YP_001784376.1 CDS HSM_1046 NC_010519.1 1203348 1203866 D PFAM: protein of unknown function DUF1706; KEGG: hso:HS_1131 hypothetical protein; hypothetical protein 1203348..1203866 Haemophilus somnus 2336 6106891 YP_001784377.1 CDS metF NC_010519.1 1204077 1204961 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 1204077..1204961 Haemophilus somnus 2336 6106892 YP_001784378.1 CDS HSM_1048 NC_010519.1 1205048 1205512 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1205048..1205512) Haemophilus somnus 2336 6106893 YP_001784379.1 CDS uvrA NC_010519.1 1205691 1208522 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrsubunit betas scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1205691..1208522 Haemophilus somnus 2336 6106894 YP_001784380.1 CDS HSM_1050 NC_010519.1 1208694 1209749 D functions in MreBCD complex in some organisms; rod shape-determining protein MreB 1208694..1209749 Haemophilus somnus 2336 6106895 YP_001784381.1 CDS HSM_1051 NC_010519.1 1209831 1210883 D in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 1209831..1210883 Haemophilus somnus 2336 6106897 YP_001784382.1 CDS HSM_1052 NC_010519.1 1210883 1211371 D PFAM: Rod shape-determining protein MreD; KEGG: hso:HS_1125 rod shape-determining protein; rod shape-determining protein MreD 1210883..1211371 Haemophilus somnus 2336 6106898 YP_001784383.1 CDS HSM_1053 NC_010519.1 1211397 1212071 R PFAM: sporulation domain protein; KEGG: hso:HS_1124 cell division protein; sporulation domain-containing protein complement(1211397..1212071) Haemophilus somnus 2336 6106899 YP_001784384.1 CDS HSM_1054 NC_010519.1 1212143 1214335 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1212143..1214335) Haemophilus somnus 2336 6106900 YP_001784385.1 CDS mazG NC_010519.1 1214340 1215161 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase complement(1214340..1215161) Haemophilus somnus 2336 6106901 YP_001784386.1 CDS HSM_1056 NC_010519.1 1215662 1216675 D KEGG: vvu:VV2_0681 hypothetical protein; hypothetical protein 1215662..1216675 Haemophilus somnus 2336 6106902 YP_001784387.1 CDS HSM_1057 NC_010519.1 1216659 1217060 D PFAM: carboxymuconolactone decarboxylase; KEGG: mth:MTH234 gamma-carboxymuconolactone decarboxylase; carboxymuconolactone decarboxylase 1216659..1217060 Haemophilus somnus 2336 6106903 YP_001784388.1 CDS HSM_1058 NC_010519.1 1217047 1218279 D PFAM: major facilitator superfamily MFS_1; KEGG: vvu:VV2_0680 permease of the major facilitator superfamily; major facilitator transporter 1217047..1218279 Haemophilus somnus 2336 6106904 YP_001784389.1 CDS HSM_1059 NC_010519.1 1218624 1219049 D PFAM: UspA domain protein; KEGG: hso:HS_1121 universal stress protein A; UspA domain-containing protein 1218624..1219049 Haemophilus somnus 2336 6106905 YP_001784390.1 CDS alaS NC_010519.1 1219241 1221865 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1219241..1221865 Haemophilus somnus 2336 6106906 YP_001784391.1 CDS HSM_1061 NC_010519.1 1222052 1222234 D PFAM: carbon storage regulator; KEGG: hit:NTHI0977 carbon storage regulator homolog; carbon storage regulator CsrA 1222052..1222234 Haemophilus somnus 2336 6106908 YP_001784392.1 CDS HSM_1062 NC_010519.1 1222268 1223632 D PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: hso:HS_1118 phosphomannomutase; phosphomannomutase 1222268..1223632 Haemophilus somnus 2336 6106909 YP_001784393.1 CDS HSM_1063 NC_010519.1 1223706 1224593 D TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: nucleotidyl transferase; KEGG: hso:HS_1117 UTP--glucose-1-phosphate uridylyltransferase; UTP-glucose-1-phosphate uridylyltransferase 1223706..1224593 Haemophilus somnus 2336 6106910 YP_001784394.1 CDS HSM_1064 NC_010519.1 1224641 1225504 R TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: hso:HS_1115 DNA adenine methylase; DNA adenine methylase complement(1224641..1225504) Haemophilus somnus 2336 6106911 YP_001784395.1 CDS aroB NC_010519.1 1225511 1226599 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(1225511..1226599) Haemophilus somnus 2336 6106912 YP_001784396.1 CDS aroK NC_010519.1 1226619 1227146 R catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase complement(1226619..1227146) Haemophilus somnus 2336 6106913 YP_001784397.1 CDS HSM_1067 NC_010519.1 1227328 1228461 R TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: hso:HS_1112 competence protein E; type IV pilus secretin PilQ complement(1227328..1228461) Haemophilus somnus 2336 6106914 YP_001784398.1 CDS HSM_1068 NC_010519.1 1228477 1228974 R KEGG: hso:HS_1111 competence protein C; competence protein C complement(1228477..1228974) Haemophilus somnus 2336 6106915 YP_001784399.1 CDS HSM_1069 NC_010519.1 1228978 1229517 R PFAM: fimbrial assembly family protein; KEGG: hso:HS_1110 competence protein B; fimbrial assembly family protein complement(1228978..1229517) Haemophilus somnus 2336 6106916 YP_001784400.1 CDS HSM_1070 NC_010519.1 1229521 1230306 R KEGG: hso:HS_1109 competence protein A; competence protein A complement(1229521..1230306) Haemophilus somnus 2336 6106917 YP_001784401.1 CDS HSM_1071 NC_010519.1 1230431 1232971 D TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: hso:HS_1108 penicillin-binding protein 1A; 1A family penicillin-binding protein 1230431..1232971 Haemophilus somnus 2336 6106918 YP_001784402.1 CDS HSM_1072 NC_010519.1 1233031 1233876 D PFAM: protein of unknown function DUF519; KEGG: hso:HS_1107 conserved hypothetical protein; hypothetical protein 1233031..1233876 Haemophilus somnus 2336 6106919 YP_001784403.1 CDS HSM_1073 NC_010519.1 1233966 1235336 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 1233966..1235336 Haemophilus somnus 2336 6106920 YP_001784404.1 CDS hfq NC_010519.1 1235543 1235833 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 1235543..1235833 Haemophilus somnus 2336 6106921 YP_001784405.1 CDS HSM_1075 NC_010519.1 1235836 1237212 D PFAM: GTP-binding protein HSR1-related; KEGG: hso:HS_1104 GTP-binding protein HflX; GTP-binding protein HSR1-related 1235836..1237212 Haemophilus somnus 2336 6106922 YP_001784406.1 CDS HSM_1076 NC_010519.1 1237229 1238170 R PFAM: sigma-54 factor interaction domain-containing protein; KEGG: hso:HS_1103 transcriptional regulatory protein; sigma-54 factor interaction domain-containing protein complement(1237229..1238170) Haemophilus somnus 2336 6106923 YP_001784407.1 CDS fumC NC_010519.1 1238377 1239771 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1238377..1239771 Haemophilus somnus 2336 6106924 YP_001784408.1 CDS HSM_1078 NC_010519.1 1239854 1240345 R KEGG: hso:HS_0669 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(1239854..1240345) Haemophilus somnus 2336 6106925 YP_001784409.1 CDS HSM_1079 NC_010519.1 1240507 1240896 D PFAM: helix-turn-helix domain protein; KEGG: hso:HS_0670 transcriptional regulator; helix-turn-helix domain-containing protein 1240507..1240896 Haemophilus somnus 2336 6106926 YP_001784410.1 CDS tyrA NC_010519.1 1241178 1242314 R catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(1241178..1242314) Haemophilus somnus 2336 6106927 YP_001784411.1 CDS HSM_1081 NC_010519.1 1242503 1243000 D TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: hso:HS_0672 phosphoribosylaminoimidazole carboxylase (AIR carboxylase); phosphoribosylaminoimidazole carboxylase catalytic subunit 1242503..1243000 Haemophilus somnus 2336 6106929 YP_001784412.1 CDS srlR NC_010519.1 1243211 1244020 R regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR complement(1243211..1244020) Haemophilus somnus 2336 6106930 YP_001784413.1 CDS HSM_1083 NC_010519.1 1244063 1244710 R TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; KEGG: hso:HS_0674 conserved phosphatase; HAD family hydrolase complement(1244063..1244710) Haemophilus somnus 2336 6106931 YP_001784414.1 CDS HSM_1084 NC_010519.1 1244785 1245153 R regulator for glucitol utilization; DNA-binding transcriptional activator GutM complement(1244785..1245153) Haemophilus somnus 2336 6106932 YP_001784415.1 CDS HSM_1085 NC_010519.1 1245208 1245996 R catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase complement(1245208..1245996) Haemophilus somnus 2336 6106933 YP_001784416.1 CDS HSM_1086 NC_010519.1 1246043 1246408 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA complement(1246043..1246408) Haemophilus somnus 2336 6106934 YP_001784417.1 CDS HSM_1087 NC_010519.1 1246469 1247464 R TIGRFAM: PTS system, glucitol/sorbitol-specific, IIBC subunit; PFAM: Sorbitol phosphotransferase protein II domain protein; KEGG: hso:HS_0678 PTS system, glucitol/sorbitol-specific IIBC component; PTS system glucitol/sorbitol-specific transporter subunit IIBC complement(1246469..1247464) Haemophilus somnus 2336 6106935 YP_001784418.1 CDS HSM_1088 NC_010519.1 1247501 1248112 R TIGRFAM: PTS system, glucitol/sorbitol-specific, IIC subunit; PFAM: PTS system protein II sorbitol-specific factor; KEGG: hso:HS_0679 PTS system, glucitol/sorbitol-specific IIC2 component; PTS system glucitol/sorbitol-specific transporter subunit IIC complement(1247501..1248112) Haemophilus somnus 2336 6106936 YP_001784419.1 CDS HSM_1089 NC_010519.1 1248725 1250077 D KEGG: fnu:FN0131 hemolysin activator protein precursor; hemolysin activation/secretion protein-like protein 1248725..1250077 Haemophilus somnus 2336 6106937 YP_001784420.1 CDS HSM_1090 NC_010519.1 1250109 1255376 D TIGRFAM: filamentous haemagglutinin family outer membrane protein; PFAM: filamentous haemagglutinin domain protein; KEGG: fnu:FN1817 hemolysin; filamentous hemagglutinin outer membrane protein 1250109..1255376 Haemophilus somnus 2336 6106938 YP_001784421.1 CDS HSM_1091 NC_010519.1 1255645 1256820 R TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: hso:HS_0680 VisC protein, monooxygenase family; UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase complement(1255645..1256820) Haemophilus somnus 2336 6106940 YP_001784422.1 CDS HSM_1092 NC_010519.1 1256847 1258046 R TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; 2-polyprenyl-6-methoxyphenol 4-hydroxylase; PFAM: monooxygenase FAD-binding; KEGG: hso:HS_0681 2-octaprenyl-6-methoxyphenol hydroxylase; 2-polyprenyl-6-methoxyphenol 4-hydroxylase complement(1256847..1258046) Haemophilus somnus 2336 6106941 YP_001784423.1 CDS HSM_1093 NC_010519.1 1258074 1259408 R PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; KEGG: hso:HS_0682 Xaa-Pro aminopeptidase (proline aminopeptidase P); peptidase M24 complement(1258074..1259408) Haemophilus somnus 2336 6106942 YP_001784424.1 CDS HSM_1094 NC_010519.1 1259564 1260121 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(1259564..1260121) Haemophilus somnus 2336 6106943 YP_001784425.1 CDS HSM_1095 NC_010519.1 1260265 1260564 D PFAM: protein of unknown function DUF710; KEGG: hso:HS_0684 hypothetical protein; hypothetical protein 1260265..1260564 Haemophilus somnus 2336 6106944 YP_001784426.1 CDS HSM_1096 NC_010519.1 1260860 1261426 D PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: hso:HS_0685 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase 1260860..1261426 Haemophilus somnus 2336 6106945 YP_001784427.1 CDS HSM_1097 NC_010519.1 1261415 1262077 R KEGG: hso:HS_0686 AphA-like regulator; AphA-like regulator complement(1261415..1262077) Haemophilus somnus 2336 6106946 YP_001784428.1 CDS serB NC_010519.1 1262181 1263134 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 1262181..1263134 Haemophilus somnus 2336 6106947 YP_001784429.1 CDS HSM_1099 NC_010519.1 1263151 1263642 D nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 1263151..1263642 Haemophilus somnus 2336 6106948 YP_001784430.1 CDS HSM_1100 NC_010519.1 1263740 1264492 R TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: hso:HS_0689 TonB protein; TonB family protein complement(1263740..1264492) Haemophilus somnus 2336 6106949 YP_001784431.1 CDS HSM_1101 NC_010519.1 1264492 1264881 R TIGRFAM: TonB system transporter ExbD type-2; PFAM: biopolymertransporter ExbD/TolR; KEGG: hso:HS_0690 biopolymer transport protein; TonB system transporter ExbD type-2 complement(1264492..1264881) Haemophilus somnus 2336 6106952 YP_001784432.1 CDS HSM_1102 NC_010519.1 1264883 1265338 R TIGRFAM: TonB-system energizer ExbB type-2; PFAM: MotA/TolQ/ExbB proton channel; KEGG: hso:HS_0691 biopolymer transporter; TonB-system energizer ExbB type-2 complement(1264883..1265338) Haemophilus somnus 2336 6106953 YP_001784433.1 CDS HSM_1103 NC_010519.1 1265732 1267105 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(1265732..1267105) Haemophilus somnus 2336 6106954 YP_001784434.1 CDS rbn NC_010519.1 1267555 1268421 D RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 1267555..1268421 Haemophilus somnus 2336 6106955 YP_001784435.1 CDS HSM_1105 NC_010519.1 1268418 1268852 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1268418..1268852 Haemophilus somnus 2336 6106956 YP_001784436.1 CDS HSM_1106 NC_010519.1 1268900 1269778 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(1268900..1269778) Haemophilus somnus 2336 6106957 YP_001784437.1 CDS HSM_1107 NC_010519.1 1269811 1270680 R PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: hso:HS_0696 RpiR family transcriptional regulator; RpiR family transcriptional regulator complement(1269811..1270680) Haemophilus somnus 2336 6106958 YP_001784438.1 CDS HSM_1108 NC_010519.1 1270661 1271182 R PFAM: conserved hypothetical protein 22; KEGG: hso:HS_0697 hypothetical protein; hypothetical protein complement(1270661..1271182) Haemophilus somnus 2336 6106959 YP_001784439.1 CDS HSM_1109 NC_010519.1 1271198 1272076 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(1271198..1272076) Haemophilus somnus 2336 6106960 YP_001784440.1 CDS HSM_1110 NC_010519.1 1272093 1272785 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(1272093..1272785) Haemophilus somnus 2336 6106961 YP_001784441.1 CDS HSM_1111 NC_010519.1 1272831 1273421 R KEGG: hso:HS_0700 N-acylneuraminate cytidylyltransferase; N-acylneuraminate cytidylyltransferase complement(1272831..1273421) Haemophilus somnus 2336 6106963 YP_001784442.1 CDS HSM_1112 NC_010519.1 1273654 1274640 D TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_0701 TRAP dicarboxylate transporter periplasmic component; TRAP dicarboxylate transporter subunit DctP 1273654..1274640 Haemophilus somnus 2336 6106964 YP_001784443.1 CDS HSM_1113 NC_010519.1 1274695 1276560 D TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: tripartite ATP-independent periplasmic transporter DctQ component; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_0702 TRAP dicarboxylate transporter permease; TRAP dicarboxylate transporter subunit DctM 1274695..1276560 Haemophilus somnus 2336 6106965 YP_001784444.1 CDS HSM_1114 NC_010519.1 1276911 1279052 D PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; SMART: KH domain protein; KEGG: hso:HS_0703 polynucleotide phosphorylase; polynucleotide phosphorylase/polyadenylase 1276911..1279052 Haemophilus somnus 2336 6106966 YP_001784445.1 CDS HSM_1115 NC_010519.1 1279455 1281260 D PFAM: helicase; DbpA RNA-binding domain protein; DEAD/DEAH box helicase; SMART: DEAD-like helicases; KEGG: hso:HS_0704 ATP-dependent RNA helicase; DEAD/DEAH box helicase 1279455..1281260 Haemophilus somnus 2336 6106967 YP_001784446.1 CDS infA NC_010519.1 1281322 1281540 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(1281322..1281540) Haemophilus somnus 2336 6106968 YP_001784447.1 CDS HSM_1117 NC_010519.1 1281751 1282422 D PFAM: acylneuraminate cytidylyltransferase; KEGG: hso:HS_0706 CMP-N-acetylneuraminic acid synthetase; N-acylneuraminate cytidylyltransferase 1281751..1282422 Haemophilus somnus 2336 6106969 YP_001784448.1 CDS HSM_1118 NC_010519.1 1282529 1283548 D TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: hso:HS_0707 dTDP-D-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase 1282529..1283548 Haemophilus somnus 2336 6106970 YP_001784449.1 CDS HSM_1119 NC_010519.1 1283815 1285401 D TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: hso:HS_0708 L-lactate permease; L-lactate transport 1283815..1285401 Haemophilus somnus 2336 6106971 YP_001784450.1 CDS HSM_1120 NC_010519.1 1285481 1286212 D PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: hso:HS_0709 hypothetical protein; hypothetical protein 1285481..1286212 Haemophilus somnus 2336 6106972 YP_001784451.1 CDS HSM_1121 NC_010519.1 1286214 1287626 D TIGRFAM: iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF162; KEGG: hso:HS_0710 hypothetical protein; iron-sulfur cluster binding protein 1286214..1287626 Haemophilus somnus 2336 6106974 YP_001784452.1 CDS HSM_1122 NC_010519.1 1287626 1288324 D PFAM: protein of unknown function DUF162; KEGG: hso:HS_0711 conserved hypothetical protein; hypothetical protein 1287626..1288324 Haemophilus somnus 2336 6106975 YP_001784453.1 CDS dipZ NC_010519.1 1288397 1290109 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(1288397..1290109) Haemophilus somnus 2336 6106976 YP_001784454.1 CDS HSM_1124 NC_010519.1 1290317 1291033 D PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: hso:HS_0713 aerobic respiration control protein; two-component response regulator 1290317..1291033 Haemophilus somnus 2336 6106977 YP_001784455.1 CDS HSM_1125 NC_010519.1 1291212 1292192 R catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C complement(1291212..1292192) Haemophilus somnus 2336 6106978 YP_001784456.1 CDS HSM_1126 NC_010519.1 1292611 1295439 D TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: hso:HS_0715 ribonuclease E; ribonuclease 1292611..1295439 Haemophilus somnus 2336 6106979 YP_001784457.1 CDS HSM_1127 NC_010519.1 1295897 1298752 R has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I complement(1295897..1298752) Haemophilus somnus 2336 6108886 YP_001784458.1 CDS HSM_1128 NC_010519.1 1298960 1300972 D TIGRFAM: ATP-dependent DNA helicase Rep; PFAM: UvrD/REP helicase; KEGG: hso:HS_0719 ATP-dependent DNA helicase; ATP-dependent DNA helicase Rep 1298960..1300972 Haemophilus somnus 2336 6106981 YP_001784459.1 CDS HSM_1129 NC_010519.1 1301649 1302638 D PFAM: phage integrase family protein; KEGG: hso:HS_1220 integrase; phage integrase family protein 1301649..1302638 Haemophilus somnus 2336 6108889 YP_001784460.1 CDS HSM_1130 NC_010519.1 1302635 1302931 R KEGG: hso:HS_1219 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(1302635..1302931) Haemophilus somnus 2336 6106983 YP_001784461.1 CDS HSM_1131 NC_010519.1 1302900 1305263 R PFAM: bacteriophage replication gene A; KEGG: spt:SPA2623 phage gene; bacteriophage replication gene A complement(1302900..1305263) Haemophilus somnus 2336 6106985 YP_001784462.1 CDS HSM_1132 NC_010519.1 1305282 1305575 R hypothetical protein complement(1305282..1305575) Haemophilus somnus 2336 6106986 YP_001784463.1 CDS HSM_1133 NC_010519.1 1305572 1305925 R hypothetical protein complement(1305572..1305925) Haemophilus somnus 2336 6106987 YP_001784464.1 CDS HSM_1134 NC_010519.1 1305941 1306231 R hypothetical protein complement(1305941..1306231) Haemophilus somnus 2336 6106988 YP_001784465.1 CDS HSM_1135 NC_010519.1 1306630 1306875 R KEGG: ecp:ECP_1147 hypothetical protein; hypothetical protein complement(1306630..1306875) Haemophilus somnus 2336 6106989 YP_001784466.1 CDS HSM_1136 NC_010519.1 1307015 1307704 D PFAM: helix-turn-helix domain protein; peptidase S24 S26A and S26B; bacteriophage CI repressor; KEGG: spt:SPA2414 transcriptional activator-regulatory protein; phage repressor 1307015..1307704 Haemophilus somnus 2336 6106990 YP_001784467.1 CDS HSM_1137 NC_010519.1 1307987 1309162 R PFAM: phage late control D family protein; KEGG: stt:t3444 regulator of late gene expression; phage late control D family protein complement(1307987..1309162) Haemophilus somnus 2336 6106991 YP_001784468.1 CDS HSM_1138 NC_010519.1 1309159 1309602 R PFAM: phage P2 GpU family protein; KEGG: sgl:SG1860 phage tail protein; phage P2 GpU family protein complement(1309159..1309602) Haemophilus somnus 2336 6106992 YP_001784469.1 CDS HSM_1139 NC_010519.1 1309807 1310115 R PFAM: phage tail E family protein; KEGG: rsp:RSP_3353 phage related tail protein; phage tail E family protein complement(1309807..1310115) Haemophilus somnus 2336 6106993 YP_001784470.1 CDS HSM_1140 NC_010519.1 1310143 1310652 R PFAM: phage major tail tube protein; KEGG: xcc:XCC2989 phage-related tail protein; phage major tail tube protein complement(1310143..1310652) Haemophilus somnus 2336 6106994 YP_001784471.1 CDS HSM_1141 NC_010519.1 1310663 1311916 R PFAM: phage tail sheath protein; KEGG: yps:YPTB1841 bacteriophage P2 tail sheath protein; phage tail sheath protein complement(1310663..1311916) Haemophilus somnus 2336 6106996 YP_001784472.1 CDS HSM_1142 NC_010519.1 1312129 1312377 D PFAM: protein of unknown function DUF172; KEGG: aeh:Mlg_1787 prevent-host-death family protein; hypothetical protein 1312129..1312377 Haemophilus somnus 2336 6106997 YP_001784473.1 CDS HSM_1143 NC_010519.1 1312377 1312640 D TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin Txe/YoeB; KEGG: aeh:Mlg_1786 addiction module toxin, Txe/YoeB family; addiction module antitoxin 1312377..1312640 Haemophilus somnus 2336 6106998 YP_001784474.1 CDS HSM_1144 NC_010519.1 1312855 1313043 D hypothetical protein 1312855..1313043 Haemophilus somnus 2336 6106999 YP_001784475.1 CDS HSM_1145 NC_010519.1 1313046 1313522 R KEGG: msu:MS0077 hypothetical protein; hypothetical protein complement(1313046..1313522) Haemophilus somnus 2336 6107000 YP_001784476.1 CDS HSM_1146 NC_010519.1 1313515 1314141 R KEGG: nme:NMB1119 hypothetical protein; hypothetical protein complement(1313515..1314141) Haemophilus somnus 2336 6107001 YP_001784477.1 CDS HSM_1147 NC_010519.1 1314204 1314455 D KEGG: tde:TDE1648 hypothetical protein; hypothetical protein 1314204..1314455 Haemophilus somnus 2336 6107002 YP_001784478.1 CDS HSM_1148 NC_010519.1 1314439 1314756 D KEGG: xfa:XF0534 hypothetical protein; hypothetical protein 1314439..1314756 Haemophilus somnus 2336 6107003 YP_001784479.1 CDS HSM_1149 NC_010519.1 1314792 1316891 R PFAM: phage tail fiber repeat 2 protein; phage Tail Collar domain protein; KEGG: nme:NMB1115 tail fibre protein; phage tail collar domain-containing protein complement(1314792..1316891) Haemophilus somnus 2336 6107004 YP_001784480.1 CDS HSM_1150 NC_010519.1 1316937 1317491 R TIGRFAM: phage tail protein I; KEGG: hit:NTHI1858 predicted bacteriophage P2-related tail formation protein gpI; phage tail protein I complement(1316937..1317491) Haemophilus somnus 2336 6107005 YP_001784481.1 CDS HSM_1151 NC_010519.1 1317481 1318395 R PFAM: Baseplate J family protein; KEGG: hit:NTHI1860 predicted phage-related baseplate assembly protein; baseplate J family protein complement(1317481..1318395) Haemophilus somnus 2336 6107007 YP_001784482.1 CDS HSM_1152 NC_010519.1 1318379 1318735 R PFAM: GPW/gp25 family protein; KEGG: hit:NTHI1861 predicted baseplate assembly protein W; GPW/gp25 family protein complement(1318379..1318735) Haemophilus somnus 2336 6107008 YP_001784483.1 CDS HSM_1153 NC_010519.1 1318735 1319361 R PFAM: phage baseplate assembly protein V; KEGG: hit:NTHI1862 predicted phage P2-like baseplate assembly protein; phage baseplate assembly protein V complement(1318735..1319361) Haemophilus somnus 2336 6107009 YP_001784484.1 CDS HSM_1154 NC_010519.1 1319575 1319922 R hypothetical protein complement(1319575..1319922) Haemophilus somnus 2336 6107010 YP_001784485.1 CDS HSM_1155 NC_010519.1 1319910 1320194 R KEGG: plu:plu2305 hypothetical protein; hypothetical protein complement(1319910..1320194) Haemophilus somnus 2336 6107011 YP_001784486.1 CDS HSM_1156 NC_010519.1 1320349 1322847 R TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: csa:Csal_1375 phage tail tape measure protein TP901, core region; TP901 family phage tail tape measure protein complement(1320349..1322847) Haemophilus somnus 2336 6107012 YP_001784487.1 CDS HSM_1157 NC_010519.1 1323613 1324074 R TIGRFAM: phage virion morphogenesis protein; PFAM: phage virion morphogenesis ( tail completion) protein; KEGG: hit:NTHI1873 probable bacteriophage tail completion protein gpS homolog; phage virion morphogenesis protein complement(1323613..1324074) Haemophilus somnus 2336 6107013 YP_001784488.1 CDS HSM_1158 NC_010519.1 1324087 1324527 R PFAM: P2 phage tail completion R family protein; KEGG: yps:YPTB1850 gpR [Enterobacteria phage P2]; P2 phage tail completion R family protein complement(1324087..1324527) Haemophilus somnus 2336 6107014 YP_001784489.1 CDS HSM_1159 NC_010519.1 1324885 1325343 R hypothetical protein complement(1324885..1325343) Haemophilus somnus 2336 6107015 YP_001784490.1 CDS HSM_1160 NC_010519.1 1325327 1325863 R PFAM: glycoside hydrolase family 24; KEGG: hso:HS_1388 lysozyme, phage-related lysozyme; glycoside hydrolase family protein complement(1325327..1325863) Haemophilus somnus 2336 6107016 YP_001784491.1 CDS HSM_1161 NC_010519.1 1325856 1326080 R KEGG: hit:NTHI1881 hypothetical protein; hypothetical protein complement(1325856..1326080) Haemophilus somnus 2336 6107018 YP_001784492.1 CDS HSM_1162 NC_010519.1 1326081 1326296 R PFAM: phage tail X family protein; KEGG: hit:NTHI1882 hypothetical protein; phage tail X family protein complement(1326081..1326296) Haemophilus somnus 2336 6107019 YP_001784493.1 CDS HSM_1163 NC_010519.1 1326296 1326808 R PFAM: phage head completion; KEGG: hit:NTHI1883 hypothetical protein; phage head completion complement(1326296..1326808) Haemophilus somnus 2336 6107020 YP_001784494.1 CDS HSM_1164 NC_010519.1 1326912 1327565 R PFAM: phage small terminase subunit; KEGG: hit:NTHI1884 predicted terminase, endonuclease subunit; phage small terminase subunit complement(1326912..1327565) Haemophilus somnus 2336 6107021 YP_001784495.1 CDS HSM_1165 NC_010519.1 1327577 1328629 R TIGRFAM: phage major capsid protein, P2 family; PFAM: phage major capsid protein P2; KEGG: hit:NTHI1885 predicted major capsid protein; P2 family phage major capsid protein complement(1327577..1328629) Haemophilus somnus 2336 6107022 YP_001784496.1 CDS HSM_1166 NC_010519.1 1328653 1329477 R PFAM: phage capsid scaffolding; KEGG: hit:NTHI1887 predicted capsid scaffolding protein; phage capsid scaffolding complement(1328653..1329477) Haemophilus somnus 2336 6107023 YP_001784497.1 CDS HSM_1167 NC_010519.1 1329641 1329985 D PFAM: terminase ATPase; KEGG: hit:NTHI1888 terminase, ATPase; terminase ATPase 1329641..1329985 Haemophilus somnus 2336 6107024 YP_001784498.1 CDS HSM_1168 NC_010519.1 1330234 1333344 R TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; PFAM: TonB-dependent receptor; KEGG: hit:NTHI0782 hemoglobin-haptoglobin binding protein B; TonB-dependent hemoglobin/transferrin/lactoferrin family receptor complement(1330234..1333344) Haemophilus somnus 2336 6107025 YP_001784499.1 CDS HSM_1169 NC_010519.1 1333587 1334108 R PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: hso:HS_0722 heme binding protein; pyridoxamine 5'-phosphate oxidase-like FMN-binding protein complement(1333587..1334108) Haemophilus somnus 2336 6107026 YP_001784500.1 CDS HSM_1170 NC_010519.1 1334126 1334620 R PFAM: protein of unknown function DUF1008; KEGG: hso:HS_0723 HugX protein; hypothetical protein complement(1334126..1334620) Haemophilus somnus 2336 6107027 YP_001784501.1 CDS rrmJ NC_010519.1 1334823 1335452 D Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 1334823..1335452 Haemophilus somnus 2336 6107029 YP_001784502.1 CDS HSM_1172 NC_010519.1 1335583 1337412 D KEGG: hso:HS_0725 cell division protein; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; ATPase AAA central domain protein; peptidase M41 FtsH extracellular; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; ATP-dependent metalloprotease FtsH 1335583..1337412 Haemophilus somnus 2336 6107030 YP_001784503.1 CDS HSM_1173 NC_010519.1 1337745 1338542 D PFAM: LicD family protein; KEGG: hso:HS_0727 lipopolysaccharide cholinephosphotransferase; LicD family protein 1337745..1338542 Haemophilus somnus 2336 6107031 YP_001784504.1 CDS HSM_1176 NC_010519.1 1339853 1340113 R KEGG: hso:HS_0728 hemin receptor, outer membrane protein; hemin receptor, outer membrane protein complement(1339853..1340113) Haemophilus somnus 2336 6107033 YP_001784505.1 CDS HSM_1177 NC_010519.1 1340138 1340428 D KEGG: spd:SPD_0914 23S rRNA (uracil-5-)-methyltransferase RumA; 23S rRNA (uracil-5-)-methyltransferase RumA 1340138..1340428 Haemophilus somnus 2336 6107034 YP_001784506.1 CDS HSM_1178 NC_010519.1 1340805 1341248 D KEGG: sha:SH2379 hypothetical protein; hypothetical protein 1340805..1341248 Haemophilus somnus 2336 6107035 YP_001784507.1 CDS HSM_1181 NC_010519.1 1342054 1342632 D KEGG: sav:SAV0404 hypothetical protein; hypothetical protein 1342054..1342632 Haemophilus somnus 2336 6107037 YP_001784508.1 CDS HSM_1182 NC_010519.1 1342706 1343545 D KEGG: dar:Daro_1916 nucleotide-binding protein containing TIR-like domain; nucleic acid-binding protein 1342706..1343545 Haemophilus somnus 2336 6107039 YP_001784509.1 CDS HSM_1183 NC_010519.1 1343736 1344005 D KEGG: spi:MGAS10750_Spy1685 hypothetical protein; hypothetical protein 1343736..1344005 Haemophilus somnus 2336 6107040 YP_001784510.1 CDS HSM_1184 NC_010519.1 1343931 1344473 R KEGG: spi:MGAS10750_Spy1699 hypothetical protein; hypothetical protein complement(1343931..1344473) Haemophilus somnus 2336 6107041 YP_001784511.1 CDS HSM_1185 NC_010519.1 1344682 1344798 D hypothetical protein 1344682..1344798 Haemophilus somnus 2336 6107042 YP_001784512.1 CDS HSM_1186 NC_010519.1 1344940 1345881 D hypothetical protein 1344940..1345881 Haemophilus somnus 2336 6107043 YP_001784513.1 CDS HSM_1187 NC_010519.1 1346067 1346642 D KEGG: neu:NE2094 hypothetical protein; hypothetical protein 1346067..1346642 Haemophilus somnus 2336 6107044 YP_001784514.1 CDS HSM_1188 NC_010519.1 1346768 1347130 D hypothetical protein 1346768..1347130 Haemophilus somnus 2336 6107045 YP_001784515.1 CDS HSM_1189 NC_010519.1 1347140 1348855 D PFAM: protein of unknown function DUF87; KEGG: neu:NE2095 hypothetical protein; hypothetical protein 1347140..1348855 Haemophilus somnus 2336 6107046 YP_001784516.1 CDS HSM_1190 NC_010519.1 1349004 1349972 R PFAM: Relaxase/mobilization nuclease family protein; KEGG: spi:MGAS10750_Spy1708 relaxase; relaxase/mobilization nuclease family protein complement(1349004..1349972) Haemophilus somnus 2336 6107047 YP_001784517.1 CDS HSM_1191 NC_010519.1 1350057 1350629 D PFAM: regulatory protein TetR; KEGG: tde:TDE0246 TetR family transcriptional regulator; TetR family transcriptional regulator 1350057..1350629 Haemophilus somnus 2336 6107049 YP_001784518.1 CDS HSM_1192 NC_010519.1 1350716 1351171 D KEGG: tde:TDE0245 ABC transporter permease/ATP-binding protein protein; ABC transporter permease/ATP-binding protein 1350716..1351171 Haemophilus somnus 2336 6107050 YP_001784519.1 CDS HSM_1193 NC_010519.1 1351225 1351563 D KEGG: tde:TDE0244 ABC transporter permease/ATP-binding protein protein; cobalt ABC transporter ATPase 1351225..1351563 Haemophilus somnus 2336 6107051 YP_001784520.1 CDS HSM_1196 NC_010519.1 1352387 1353214 D TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; KEGG: hso:HS_0729 dihydropteroate synthase; dihydropteroate synthase 1352387..1353214 Haemophilus somnus 2336 6107053 YP_001784521.1 CDS glmM NC_010519.1 1353305 1354639 D catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1353305..1354639 Haemophilus somnus 2336 6107054 YP_001784522.1 CDS HSM_1198 NC_010519.1 1354653 1355120 D TIGRFAM: phosphohistidine phosphatase SixA; PFAM: phosphoglycerate mutase; KEGG: hso:HS_0731 phosphohistidine phosphatase; phosphohistidine phosphatase SixA 1354653..1355120 Haemophilus somnus 2336 6107055 YP_001784523.1 CDS HSM_1199 NC_010519.1 1355125 1356084 D PFAM: Auxin Efflux Carrier; KEGG: hso:HS_0732 conserved hypothetical protein; hypothetical protein 1355125..1356084 Haemophilus somnus 2336 6107056 YP_001784524.1 CDS HSM_1200 NC_010519.1 1356212 1358134 D SMART: helicase c2; KEGG: hso:HS_0733 ATP-dependent DNA helicase; helicase c2 1356212..1358134 Haemophilus somnus 2336 6107057 YP_001784525.1 CDS HSM_1201 NC_010519.1 1358139 1358855 D PFAM: peptidase M22 glycoprotease; KEGG: hso:HS_0734 glycoprotease family protein; peptidase M22 glycoprotease 1358139..1358855 Haemophilus somnus 2336 6107060 YP_001784526.1 CDS HSM_1202 NC_010519.1 1359081 1360763 D Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1359081..1360763 Haemophilus somnus 2336 6107061 YP_001784527.1 CDS HSM_1203 NC_010519.1 1360869 1362014 D TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: hso:HS_0736 ribonuclease D; ribonuclease D 1360869..1362014 Haemophilus somnus 2336 6107062 YP_001784528.1 CDS HSM_1204 NC_010519.1 1362132 1362719 R PFAM: transport-associated; SMART: transport-associated and nodulation region; KEGG: hso:HS_0737 hemolysin; hypothetical protein complement(1362132..1362719) Haemophilus somnus 2336 6107063 YP_001784529.1 CDS HSM_1205 NC_010519.1 1362781 1363365 R KEGG: hso:HS_0738 conserved hypothetical protein; hypothetical protein complement(1362781..1363365) Haemophilus somnus 2336 6107064 YP_001784530.1 CDS HSM_1206 NC_010519.1 1363371 1363733 R PFAM: protein of unknown function UPF0102; KEGG: hso:HS_0739 conserved hypothetical protein; hypothetical protein complement(1363371..1363733) Haemophilus somnus 2336 6107065 YP_001784531.1 CDS HSM_1207 NC_010519.1 1363730 1365490 R PFAM: LppC family lipoprotein; KEGG: hso:HS_0740 LppC precursor; LppC family lipoprotein complement(1363730..1365490) Haemophilus somnus 2336 6107066 YP_001784532.1 CDS HSM_1208 NC_010519.1 1365576 1366421 D PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: hso:HS_0741 conserved hypothetical protein; uroporphyrin-III C/tetrapyrrole methyltransferase 1365576..1366421 Haemophilus somnus 2336 6107067 YP_001784533.1 CDS HSM_1209 NC_010519.1 1366498 1367121 D TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: hso:HS_0742 conserved hypothetical protein; Sua5/YciO/YrdC/YwlC family protein 1366498..1367121 Haemophilus somnus 2336 6107068 YP_001784534.1 CDS HSM_1210 NC_010519.1 1367182 1368228 D PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: hso:HS_0743 ribosomal large subunit pseudouridine synthase B; pseudouridine synthase 1367182..1368228 Haemophilus somnus 2336 6107069 YP_001784535.1 CDS HSM_1211 NC_010519.1 1368276 1368929 D KEGG: hso:HS_1709 transposase; transposase 1368276..1368929 Haemophilus somnus 2336 6107071 YP_001784536.1 CDS HSM_1212 NC_010519.1 1369169 1370338 R PFAM: Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0602 adhesin; hemagluttinin domain-containing protein complement(1369169..1370338) Haemophilus somnus 2336 6107072 YP_001784537.1 CDS HSM_1213 NC_010519.1 1370817 1372202 R PFAM: outer membrane efflux protein; KEGG: hso:HS_0746 outer membrane protein; outer membrane efflux protein complement(1370817..1372202) Haemophilus somnus 2336 6107073 YP_001784538.1 CDS HSM_1214 NC_010519.1 1372333 1373064 R PFAM: regulatory protein DeoR; regulatory protein DeoR; KEGG: hso:HS_0747 deoxyribose operon repressor; DeoR family transcriptional regulator complement(1372333..1373064) Haemophilus somnus 2336 6107074 YP_001784539.1 CDS HSM_1215 NC_010519.1 1373089 1373763 R catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase complement(1373089..1373763) Haemophilus somnus 2336 6107075 YP_001784540.1 CDS HSM_1216 NC_010519.1 1373933 1374853 D TIGRFAM: ribokinase; PFAM: PfkB domain protein; KEGG: hso:HS_0749 ribokinase; ribokinase 1373933..1374853 Haemophilus somnus 2336 6107076 YP_001784541.1 CDS HSM_1217 NC_010519.1 1374864 1376156 D TIGRFAM: L-fucose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_0750 fucose permease; L-fucose transporter 1374864..1376156 Haemophilus somnus 2336 6107077 YP_001784542.1 CDS HSM_1218 NC_010519.1 1376158 1377171 D KEGG: hso:HS_0751 hypothetical protein; hypothetical protein 1376158..1377171 Haemophilus somnus 2336 6107078 YP_001784543.1 CDS rplM NC_010519.1 1377440 1377868 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1377440..1377868 Haemophilus somnus 2336 6107079 YP_001784544.1 CDS rpsI NC_010519.1 1377885 1378277 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1377885..1378277 Haemophilus somnus 2336 6107080 YP_001784545.1 CDS HSM_1221 NC_010519.1 1378422 1379060 D PFAM: glutathione S-transferase domain; KEGG: hso:HS_0754 stringent starvation protein A; glutathione S-transferase 1378422..1379060 Haemophilus somnus 2336 6107082 YP_001784546.1 CDS HSM_1222 NC_010519.1 1379068 1379523 D PFAM: stringent starvation protein B; KEGG: hso:HS_0755 stringent starvation protein B; ClpXP protease specificity-enhancing factor 1379068..1379523 Haemophilus somnus 2336 6107083 YP_001784547.1 CDS asnC NC_010519.1 1379596 1380999 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1379596..1380999) Haemophilus somnus 2336 6107084 YP_001784548.1 CDS HSM_1224 NC_010519.1 1381202 1382419 D KEGG: hso:HS_0757 NagC-like transcriptional regulator; NagC-like transcriptional regulator 1381202..1382419 Haemophilus somnus 2336 6107085 YP_001784549.1 CDS HSM_1225 NC_010519.1 1382555 1383343 R PFAM: regulatory protein IclR; IclR family transcripitonal regulator; KEGG: hso:HS_0758 transcriptional regulator, IclR family; IclR family transcripitonal regulator complement(1382555..1383343) Haemophilus somnus 2336 6107086 YP_001784550.1 CDS HSM_1226 NC_010519.1 1383566 1384564 D NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 1383566..1384564 Haemophilus somnus 2336 6107087 YP_001784551.1 CDS HSM_1227 NC_010519.1 1384669 1385151 D PFAM: tripartite ATP-independent periplasmic transporter DctQ component; KEGG: hso:HS_0760 tripartite ATP-independent periplasmic transporters, DctQ component; tripartite ATP-independent periplasmic transporter DctQ 1384669..1385151 Haemophilus somnus 2336 6107088 YP_001784552.1 CDS HSM_1228 NC_010519.1 1385148 1386428 D TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: citrate transporter; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_0761 integral membrane protein, DedA family; TRAP dicarboxylate transporter subunit DctM 1385148..1386428 Haemophilus somnus 2336 6107089 YP_001784553.1 CDS HSM_1229 NC_010519.1 1386448 1387434 D TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_0762 C4-dicarboxylate transporter, periplasmic component; TRAP dicarboxylate transporter subunit DctP 1386448..1387434 Haemophilus somnus 2336 6107090 YP_001784554.1 CDS HSM_1230 NC_010519.1 1387514 1389031 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0763 ribose ABC transporter ATP-binding protein; ABC transporter 1387514..1389031 Haemophilus somnus 2336 6107091 YP_001784555.1 CDS HSM_1231 NC_010519.1 1389074 1390123 D PFAM: inner-membrane translocator; KEGG: hso:HS_0764 ribose ABC transporter permease; monosaccharide-transporting ATPase 1389074..1390123 Haemophilus somnus 2336 6107093 YP_001784556.1 CDS HSM_1232 NC_010519.1 1390161 1391270 D KEGG: hso:HS_0765 sugar ABC transporter periplasmic protein; sugar ABC transporter periplasmic protein 1390161..1391270 Haemophilus somnus 2336 6107094 YP_001784557.1 CDS HSM_1233 NC_010519.1 1391333 1392220 D PFAM: SMP-30/gluconolaconase/LRE domain protein; KEGG: hso:HS_0766 conserved hypothetical protein; SMP-30/gluconolaconase/LRE domain-containing protein 1391333..1392220 Haemophilus somnus 2336 6107095 YP_001784558.1 CDS HSM_1234 NC_010519.1 1392287 1393225 R PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: hso:HS_0767 sugar ABC transporter periplasmic sugar-binding protein; monosaccharide-transporting ATPase complement(1392287..1393225) Haemophilus somnus 2336 6107096 YP_001784559.1 CDS HSM_1235 NC_010519.1 1393440 1394930 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0768 ribose ABC transporter ATP-binding protein; ABC transporter 1393440..1394930 Haemophilus somnus 2336 6107097 YP_001784560.1 CDS HSM_1236 NC_010519.1 1394939 1395967 D PFAM: inner-membrane translocator; KEGG: hso:HS_0769 ribose transporter permease; monosaccharide-transporting ATPase 1394939..1395967 Haemophilus somnus 2336 6107098 YP_001784561.1 CDS HSM_1237 NC_010519.1 1396069 1397523 D PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_0770 L-xylulose kinase; carbohydrate kinase FGGY 1396069..1397523 Haemophilus somnus 2336 6107099 YP_001784562.1 CDS ulaD NC_010519.1 1397534 1398181 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 1397534..1398181 Haemophilus somnus 2336 6107100 YP_001784563.1 CDS HSM_1239 NC_010519.1 1398198 1399070 D L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 1398198..1399070 Haemophilus somnus 2336 6107101 YP_001784564.1 CDS sgbE NC_010519.1 1399064 1399759 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 1399064..1399759 Haemophilus somnus 2336 6107102 YP_001784565.1 CDS HSM_1241 NC_010519.1 1399802 1400623 R TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: hso:HS_0774 hydrolase, HAD superfamily; cof family hydrolase complement(1399802..1400623) Haemophilus somnus 2336 6107104 YP_001784566.1 CDS HSM_1242 NC_010519.1 1400862 1401818 D PFAM: alpha/beta hydrolase; KEGG: hso:HS_0775 lysophospholipase L2; lysophospholipase 1400862..1401818 Haemophilus somnus 2336 6107105 YP_001784567.1 CDS HSM_1243 NC_010519.1 1401796 1402179 R TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; KEGG: hso:HS_0776 CrcB protein; CrcB protein complement(1401796..1402179) Haemophilus somnus 2336 6107106 YP_001784568.1 CDS HSM_1244 NC_010519.1 1402199 1403017 R TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: hso:HS_0777 hydrolase, haloacid dehalogenase-like family; cof family hydrolase complement(1402199..1403017) Haemophilus somnus 2336 6107107 YP_001784569.1 CDS HSM_1245 NC_010519.1 1403055 1403717 R PFAM: nitroreductase; KEGG: hso:HS_0778 NAD(P)H nitroreductase; nitroreductase complement(1403055..1403717) Haemophilus somnus 2336 6107108 YP_001784570.1 CDS HSM_1246 NC_010519.1 1403738 1404034 R PFAM: conserved hypothetical protein 743; KEGG: hso:HS_0779 hypothetical protein; hypothetical protein complement(1403738..1404034) Haemophilus somnus 2336 6107109 YP_001784571.1 CDS HSM_1247 NC_010519.1 1404059 1405270 R TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; KEGG: hso:HS_0780 tyrosine-specific transporter; aromatic amino acid transporter complement(1404059..1405270) Haemophilus somnus 2336 6107110 YP_001784572.1 CDS HSM_1248 NC_010519.1 1405364 1406413 R PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: hso:HS_0781 iron(III) ABC transporter ATP-binding protein; ABC transporter complement(1405364..1406413) Haemophilus somnus 2336 6107111 YP_001784573.1 CDS HSM_1249 NC_010519.1 1406413 1408080 R PFAM: binding-protein-dependent transporters inner membrane component; KEGG: hso:HS_0782 iron-uptake permease inner membrane protein; binding-protein-dependent transporters inner membrane component complement(1406413..1408080) Haemophilus somnus 2336 6107112 YP_001784574.1 CDS HSM_1250 NC_010519.1 1408237 1409253 R PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_0783 periplasmic iron-binding protein; extracellular solute-binding protein complement(1408237..1409253) Haemophilus somnus 2336 6107113 YP_001784575.1 CDS HSM_1251 NC_010519.1 1409444 1411141 R component of the membrane-bound D-lactate oxidase FAD-binding, NADH independent; D-lactate dehydrogenase complement(1409444..1411141) Haemophilus somnus 2336 6107115 YP_001784576.1 CDS HSM_1252 NC_010519.1 1411347 1412174 D TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; PFAM: transferase hexapeptide repeat containing protein; KEGG: hso:HS_0785 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1411347..1412174 Haemophilus somnus 2336 6107116 YP_001784577.1 CDS purU NC_010519.1 1412232 1413068 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1412232..1413068) Haemophilus somnus 2336 6107117 YP_001784578.1 CDS HSM_1254 NC_010519.1 1413130 1413534 R PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: hso:HS_0787 DNA-binding protein H-NS; histone family protein nucleoid-structuring protein H-NS complement(1413130..1413534) Haemophilus somnus 2336 6107118 YP_001784579.1 CDS HSM_1255 NC_010519.1 1413975 1415522 D PFAM: Na? antiporter NhaC; KEGG: hso:HS_0788 Na(+)/H(+) antiporter; hypothetical protein 1413975..1415522 Haemophilus somnus 2336 6107119 YP_001784580.1 CDS HSM_1256 NC_010519.1 1415647 1416663 D TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: hso:HS_0789 UDP-glucose-4-epimerase; UDP-glucose 4-epimerase 1415647..1416663 Haemophilus somnus 2336 6107120 YP_001784581.1 CDS HSM_1257 NC_010519.1 1417252 1431222 D PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790 large adhesin; YadA domain-containing protein 1417252..1431222 Haemophilus somnus 2336 6107121 YP_001784582.1 CDS HSM_1258 NC_010519.1 1431330 1433366 R PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: hso:HS_0791 oligopeptidase A; oligopeptidase A complement(1431330..1433366) Haemophilus somnus 2336 6107122 YP_001784583.1 CDS HSM_1259 NC_010519.1 1433653 1434843 D PFAM: aminotransferase class I and II; KEGG: hso:HS_0792 aminotransferase; aspartate transaminase 1433653..1434843 Haemophilus somnus 2336 6107123 YP_001784584.1 CDS HSM_1260 NC_010519.1 1434833 1436242 D TIGRFAM: Na+/H+ antiporter NhaC; PFAM: Na? antiporter NhaC; KEGG: hso:HS_0793 Na(+)/H(+) antiporter; Na+/H+ antiporter NhaC 1434833..1436242 Haemophilus somnus 2336 6107124 YP_001784585.1 CDS HSM_1261 NC_010519.1 1436388 1437551 D PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: hso:HS_0794 xylose operon regulatory protein; helix-turn-helix domain-containing protein 1436388..1437551 Haemophilus somnus 2336 6107126 YP_001784586.1 CDS HSM_1262 NC_010519.1 1437659 1438021 D PFAM: protein of unknown function DUF454; KEGG: hso:HS_0795 hypothetical protein; hypothetical protein 1437659..1438021 Haemophilus somnus 2336 6107127 YP_001784587.1 CDS HSM_1263 NC_010519.1 1438143 1439642 D PFAM: extracellular solute-binding protein family 5; KEGG: hso:HS_0796 oligopeptide transporter periplasmic-binding protein; 4-phytase 1438143..1439642 Haemophilus somnus 2336 6107128 YP_001784588.1 CDS HSM_1266 NC_010519.1 1441896 1443251 D PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: hso:HS_1548 outer membrane protein P1; aromatic hydrocarbon degradation membrane protein 1441896..1443251 Haemophilus somnus 2336 6107130 YP_001784589.1 CDS HSM_1267 NC_010519.1 1443357 1444010 R KEGG: hso:HS_1709 transposase; transposase complement(1443357..1444010) Haemophilus somnus 2336 6107131 YP_001784590.1 CDS HSM_1268 NC_010519.1 1444095 1445081 R PFAM: dihydroorotate dehydrogenase; KEGG: hso:HS_0799 hypothetical protein; dihydroorotate dehydrogenase complement(1444095..1445081) Haemophilus somnus 2336 6107132 YP_001784591.1 CDS HSM_1269 NC_010519.1 1445445 1446674 R TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: hso:HS_0800 tryptophan permease, tryptophan/tyrosine permease family; aromatic amino acid transporter complement(1445445..1446674) Haemophilus somnus 2336 6107133 YP_001784592.1 CDS tnaA NC_010519.1 1446740 1448155 R tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase complement(1446740..1448155) Haemophilus somnus 2336 6107134 YP_001784593.1 CDS HSM_1271 NC_010519.1 1448477 1450615 R catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase complement(1448477..1450615) Haemophilus somnus 2336 6107136 YP_001784594.1 CDS HSM_1272 NC_010519.1 1450683 1451879 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(1450683..1451879) Haemophilus somnus 2336 6107137 YP_001784595.1 CDS HSM_1273 NC_010519.1 1452110 1452544 D PFAM: protein of unknown function DUF412; KEGG: hso:HS_0804 hypothetical protein; hypothetical protein 1452110..1452544 Haemophilus somnus 2336 6107138 YP_001784596.1 CDS HSM_1274 NC_010519.1 1452657 1452935 D PFAM: protein of unknown function DUF709; KEGG: hso:HS_0805 hypothetical protein; hypothetical protein 1452657..1452935 Haemophilus somnus 2336 6107139 YP_001784597.1 CDS HSM_1275 NC_010519.1 1453033 1455501 R TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: hso:HS_0806 trimethylamine-N-oxide reductase 2, biotin sulfoxide reductase; molybdopterin guanine dinucleotide-containing S/N-oxide reductase complement(1453033..1455501) Haemophilus somnus 2336 6107140 YP_001784598.1 CDS HSM_1276 NC_010519.1 1455769 1456890 R PFAM: NapC/NirT cytochrome C domain protein; KEGG: hso:HS_0807 cytochrome C protein; NapC/NirT cytochrome C domain-containing protein complement(1455769..1456890) Haemophilus somnus 2336 6107141 YP_001784599.1 CDS HSM_1277 NC_010519.1 1457077 1457802 R KEGG: hso:HS_0808 SAM-dependent methyltransferase; SAM-dependent methyltransferase complement(1457077..1457802) Haemophilus somnus 2336 6107142 YP_001784600.1 CDS HSM_1278 NC_010519.1 1457836 1458537 D PFAM: beta-lactamase; KEGG: hso:HS_0809 hydroxyacylglutathione hydrolase; hydroxyacylglutathione hydrolase 1457836..1458537 Haemophilus somnus 2336 6107143 YP_001784601.1 CDS hemA NC_010519.1 1458648 1459949 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1458648..1459949 Haemophilus somnus 2336 6107144 YP_001784602.1 CDS HSM_1280 NC_010519.1 1459961 1461355 R NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein complement(1459961..1461355) Haemophilus somnus 2336 6107145 YP_001784603.1 CDS HSM_1281 NC_010519.1 1461409 1462017 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1461409..1462017 Haemophilus somnus 2336 6107147 YP_001784604.1 CDS HSM_1282 NC_010519.1 1462070 1463410 R PFAM: ATPase AAA; SMART: AAA ATPase; KEGG: hso:HS_0813 conserved hypothetical protein; recombination factor protein RarA complement(1462070..1463410) Haemophilus somnus 2336 6107148 YP_001784605.1 CDS lolA NC_010519.1 1463476 1464090 R participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein complement(1463476..1464090) Haemophilus somnus 2336 6107149 YP_001784606.1 CDS HSM_1284 NC_010519.1 1464302 1464715 D PFAM: protein of unknown function DUF1043; KEGG: hso:HS_0815 hypothetical protein; hypothetical protein 1464302..1464715 Haemophilus somnus 2336 6107150 YP_001784607.1 CDS HSM_1285 NC_010519.1 1464832 1466232 D TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: hso:HS_0816 periplasmic serine protease; protease Do 1464832..1466232 Haemophilus somnus 2336 6107151 YP_001784608.1 CDS HSM_1286 NC_010519.1 1466317 1466793 R PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: hso:HS_0817 low molecular weight protein-tyrosine-phosphatase; protein tyrosine phosphatase complement(1466317..1466793) Haemophilus somnus 2336 6107152 YP_001784609.1 CDS HSM_1287 NC_010519.1 1466926 1467648 D KEGG: hso:HS_0818 hypothetical protein; Mn2+-dependent serine/threonine protein kinase 1466926..1467648 Haemophilus somnus 2336 6107153 YP_001784610.1 CDS HSM_1288 NC_010519.1 1468073 1468534 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1468073..1468534 Haemophilus somnus 2336 6108890 YP_001784611.1 CDS nusA NC_010519.1 1468549 1470030 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1468549..1470030 Haemophilus somnus 2336 6107155 YP_001784612.1 CDS infB NC_010519.1 1470051 1472546 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1470051..1472546 Haemophilus somnus 2336 6107156 YP_001784613.1 CDS rbfA NC_010519.1 1472800 1473180 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1472800..1473180 Haemophilus somnus 2336 6107158 YP_001784614.1 CDS truB NC_010519.1 1473193 1474119 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1473193..1474119 Haemophilus somnus 2336 6107159 YP_001784615.1 CDS HSM_1293 NC_010519.1 1474167 1476440 R catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase complement(1474167..1476440) Haemophilus somnus 2336 6107160 YP_001784616.1 CDS HSM_1294 NC_010519.1 1476646 1478970 R TIGRFAM: penicillin-binding protein 1B; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: hso:HS_0825 penicillin-binding protein 1B; penicillin-binding protein 1B complement(1476646..1478970) Haemophilus somnus 2336 6107161 YP_001784617.1 CDS HSM_1295 NC_010519.1 1478982 1479344 R PFAM: uncharacterised conserved protein UCP006287; KEGG: hso:HS_0826 hypothetical protein; hypothetical protein complement(1478982..1479344) Haemophilus somnus 2336 6107162 YP_001784618.1 CDS HSM_1296 NC_010519.1 1479348 1479689 R TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: hso:HS_0827 HesB family protein; iron-sulfur cluster assembly accessory protein complement(1479348..1479689) Haemophilus somnus 2336 6107163 YP_001784619.1 CDS HSM_1297 NC_010519.1 1479791 1480612 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1479791..1480612 Haemophilus somnus 2336 6107164 YP_001784620.1 CDS glnD NC_010519.1 1480670 1483255 D KEGG: hso:HS_0829 uridylyltransferase; TIGRFAM: protein-P-II uridylyltransferase; PFAM: amino acid-binding ACT domain protein; DNA polymerase beta domain protein region; metal-dependent phosphohydrolase HD sub domain; GlnD PII-uridylyltransferase; SMART: metal-dependent phosphohydrolase HD region; PII uridylyl-transferase 1480670..1483255 Haemophilus somnus 2336 6107165 YP_001784621.1 CDS ribH NC_010519.1 1483334 1483807 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; subunit beta of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1483334..1483807 Haemophilus somnus 2336 6107166 YP_001784622.1 CDS nusB NC_010519.1 1483816 1484250 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1483816..1484250 Haemophilus somnus 2336 6107167 YP_001784623.1 CDS HSM_1301 NC_010519.1 1484265 1485272 D TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein domain protein; KEGG: hso:HS_0832 thiamine-monophosphate kinase; thiamine-monophosphate kinase 1484265..1485272 Haemophilus somnus 2336 6107170 YP_001784624.1 CDS HSM_1302 NC_010519.1 1485282 1485767 D PFAM: phosphatidylglycerophosphatase A; KEGG: hso:HS_0833 phosphatidylglycerophosphatase A; phosphatidylglycerophosphatase A 1485282..1485767 Haemophilus somnus 2336 6107171 YP_001784625.1 CDS HSM_1303 NC_010519.1 1485780 1486409 D PFAM: lysine exporter (LYSE/YGGA); KEGG: hso:HS_0834 lysine exporter protein; lysine exporter protein LysE/YggA 1485780..1486409 Haemophilus somnus 2336 6107172 YP_001784626.1 CDS HSM_1304 NC_010519.1 1486428 1487240 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1486428..1487240 Haemophilus somnus 2336 6107173 YP_001784627.1 CDS HSM_1305 NC_010519.1 1487407 1488210 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1487407..1488210 Haemophilus somnus 2336 6107174 YP_001784628.1 CDS HSM_1306 NC_010519.1 1488221 1489000 D PFAM: protein of unknown function DUF1260; KEGG: hso:HS_0837 hypothetical protein; hypothetical protein 1488221..1489000 Haemophilus somnus 2336 6107175 YP_001784629.1 CDS HSM_1307 NC_010519.1 1489055 1490245 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(1489055..1490245) Haemophilus somnus 2336 6107176 YP_001784630.1 CDS HSM_1308 NC_010519.1 1490390 1491478 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(1490390..1491478) Haemophilus somnus 2336 6107177 YP_001784631.1 CDS HSM_1309 NC_010519.1 1491521 1492213 R PFAM: carbonic anhydrase; KEGG: hso:HS_0840 carbonic anhydrase; carbonate dehydratase complement(1491521..1492213) Haemophilus somnus 2336 6107178 YP_001784632.1 CDS trpA NC_010519.1 1492323 1493132 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1492323..1493132) Haemophilus somnus 2336 6107179 YP_001784633.1 CDS HSM_1311 NC_010519.1 1493132 1494328 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1493132..1494328) Haemophilus somnus 2336 6107181 YP_001784634.1 CDS HSM_1312 NC_010519.1 1494338 1495756 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1494338..1495756) Haemophilus somnus 2336 6107182 YP_001784635.1 CDS trpD NC_010519.1 1495769 1496773 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1495769..1496773) Haemophilus somnus 2336 6107183 YP_001784636.1 CDS HSM_1314 NC_010519.1 1496818 1497423 R TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(1496818..1497423) Haemophilus somnus 2336 6107184 YP_001784637.1 CDS HSM_1315 NC_010519.1 1497433 1498974 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1497433..1498974) Haemophilus somnus 2336 6107185 YP_001784638.1 CDS HSM_1316 NC_010519.1 1499189 1500247 D SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1499189..1500247 Haemophilus somnus 2336 6107186 YP_001784639.1 CDS HSM_1317 NC_010519.1 1500431 1501252 D PFAM: OmpA/MotB domain protein; SmpA/OmlA domain protein; KEGG: hso:HS_0842 outer membrane protein; SmpA/OmlA domain-containing protein 1500431..1501252 Haemophilus somnus 2336 6107187 YP_001784640.1 CDS HSM_1318 NC_010519.1 1501303 1502184 R PFAM: aminoglycoside phosphotransferase; fructosamine kinase; KEGG: hso:HS_0843 fructosamine kinase family enzyme; fructosamine kinase complement(1501303..1502184) Haemophilus somnus 2336 6107188 YP_001784641.1 CDS HSM_1319 NC_010519.1 1502565 1504493 D catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1502565..1504493 Haemophilus somnus 2336 6107189 YP_001784642.1 CDS HSM_1320 NC_010519.1 1504549 1505397 R PFAM: thioredoxin domain; KEGG: hso:HS_0845 conserved hypothetical protein; thioredoxin complement(1504549..1505397) Haemophilus somnus 2336 6107190 YP_001784643.1 CDS HSM_1321 NC_010519.1 1505734 1507044 D PFAM: xanthine/uracil/vitamin C permease; KEGG: hso:HS_0846 permease, xanthine/uracil family; xanthine/uracil/vitamin C permease 1505734..1507044 Haemophilus somnus 2336 6107192 YP_001784644.1 CDS HSM_1322 NC_010519.1 1507126 1507662 D PFAM: protein of unknown function DUF462; KEGG: hso:HS_0847 hypothetical protein; hypothetical protein 1507126..1507662 Haemophilus somnus 2336 6107193 YP_001784645.1 CDS HSM_1323 NC_010519.1 1507663 1508592 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0848 ABC-type multidrug transporter, ATP-binding protein; ABC transporter 1507663..1508592 Haemophilus somnus 2336 6107194 YP_001784646.1 CDS HSM_1324 NC_010519.1 1508592 1509356 D PFAM: ABC transporter; KEGG: hso:HS_0849 ABC-type multidrug transporter, permease; ABC transporter 1508592..1509356 Haemophilus somnus 2336 6107195 YP_001784647.1 CDS HSM_1325 NC_010519.1 1509466 1510848 R PFAM: conserved hypothetical protein 730; KEGG: hso:HS_0850 conserved hypothetical protein; hypothetical protein complement(1509466..1510848) Haemophilus somnus 2336 6107196 YP_001784648.1 CDS queF NC_010519.1 1510861 1511700 R catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(1510861..1511700) Haemophilus somnus 2336 6107197 YP_001784649.1 CDS HSM_1327 NC_010519.1 1511716 1512504 R KEGG: hso:HS_0852 hypothetical protein; hypothetical protein complement(1511716..1512504) Haemophilus somnus 2336 6107198 YP_001784650.1 CDS HSM_1328 NC_010519.1 1512590 1512904 D PFAM: protein of unknown function DUF446; KEGG: hso:HS_0853 hypothetical protein; hypothetical protein 1512590..1512904 Haemophilus somnus 2336 6107199 YP_001784651.1 CDS HSM_1329 NC_010519.1 1512889 1513611 D catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 1512889..1513611 Haemophilus somnus 2336 6107200 YP_001784652.1 CDS HSM_1330 NC_010519.1 1513638 1513805 D PFAM: protein of unknown function UPF0181; KEGG: hso:HS_0855 hypothetical protein; hypothetical protein 1513638..1513805 Haemophilus somnus 2336 6107201 YP_001784653.1 CDS HSM_1331 NC_010519.1 1513955 1514164 D TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: hso:HS_0856 cold shock-like protein; cold-shock DNA-binding domain-containing protein 1513955..1514164 Haemophilus somnus 2336 6107203 YP_001784654.1 CDS HSM_1332 NC_010519.1 1514236 1514682 R PFAM: protein of unknown function DUF1047; KEGG: hso:HS_0857 hypothetical protein; hypothetical protein complement(1514236..1514682) Haemophilus somnus 2336 6107204 YP_001784655.1 CDS HSM_1333 NC_010519.1 1514834 1516645 D KEGG: hso:HS_0858 ATP-dependent Lon protease; ATP-dependent Lon protease 1514834..1516645 Haemophilus somnus 2336 6107205 YP_001784656.1 CDS pheS NC_010519.1 1516740 1517729 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1516740..1517729 Haemophilus somnus 2336 6107206 YP_001784657.1 CDS HSM_1335 NC_010519.1 1517744 1518223 D KEGG: hso:HS_0860 hypothetical protein; hypothetical protein 1517744..1518223 Haemophilus somnus 2336 6107207 YP_001784658.1 CDS pheT NC_010519.1 1518238 1520625 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1518238..1520625 Haemophilus somnus 2336 6107208 YP_001784659.1 CDS ihfA NC_010519.1 1520628 1520921 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1520628..1520921 Haemophilus somnus 2336 6107209 YP_001784660.1 CDS HSM_1338 NC_010519.1 1521065 1522009 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1521065..1522009) Haemophilus somnus 2336 6107210 YP_001784661.1 CDS HSM_1339 NC_010519.1 1522217 1523539 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1522217..1523539 Haemophilus somnus 2336 6107211 YP_001784662.1 CDS HSM_1340 NC_010519.1 1523606 1524349 D acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1523606..1524349 Haemophilus somnus 2336 6107212 YP_001784663.1 CDS mukB NC_010519.1 1524349 1528878 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1524349..1528878 Haemophilus somnus 2336 6107214 YP_001784664.1 CDS HSM_1344 NC_010519.1 1529865 1530719 D PFAM: protein of unknown function DUF6 transmembrane; KEGG: hso:HS_0867 permease; hypothetical protein 1529865..1530719 Haemophilus somnus 2336 6107216 YP_001784665.1 CDS HSM_1345 NC_010519.1 1530731 1531099 D KEGG: hso:HS_0868 hypothetical protein; type I restriction-modification system methyltransferase subunit-like protein 1530731..1531099 Haemophilus somnus 2336 6107217 YP_001784666.1 CDS HSM_1346 NC_010519.1 1531209 1532270 D KEGG: hso:HS_0870 hypothetical protein; hypothetical protein 1531209..1532270 Haemophilus somnus 2336 6107218 YP_001784667.1 CDS HSM_1347 NC_010519.1 1532380 1532478 D KEGG: hso:HS_0871 hypothetical protein; hypothetical protein 1532380..1532478 Haemophilus somnus 2336 6107219 YP_001784668.1 CDS HSM_1348 NC_010519.1 1532521 1532637 D KEGG: hso:HS_0871 hypothetical protein; hypothetical protein 1532521..1532637 Haemophilus somnus 2336 6107220 YP_001784669.1 CDS HSM_1349 NC_010519.1 1532655 1532756 D KEGG: sfr:Sfri_1956 type I site-specific deoxyribonuclease, HsdR family protein; type I site-specific deoxyribonuclease, HsdR family protein 1532655..1532756 Haemophilus somnus 2336 6107221 YP_001784670.1 CDS sbcB NC_010519.1 1532799 1534229 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 1532799..1534229 Haemophilus somnus 2336 6107222 YP_001784671.1 CDS HSM_1351 NC_010519.1 1534340 1534759 D KEGG: bfs:BF2816 hypothetical protein; hypothetical protein 1534340..1534759 Haemophilus somnus 2336 6107224 YP_001784672.1 CDS HSM_1352 NC_010519.1 1535261 1535548 R the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 complement(1535261..1535548) Haemophilus somnus 2336 6107225 YP_001784673.1 CDS HSM_1353 NC_010519.1 1535769 1536374 D PFAM: SNARE associated Golgi protein; KEGG: hso:HS_0874 hypothetical protein; hypothetical protein 1535769..1536374 Haemophilus somnus 2336 6107226 YP_001784674.1 CDS rplT NC_010519.1 1536547 1536900 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1536547..1536900) Haemophilus somnus 2336 6107227 YP_001784675.1 CDS rpmI NC_010519.1 1536971 1537168 R PFAM: ribosomal protein L35; KEGG: hso:HS_0876 50S ribosomal protein L35; 50S ribosomal protein L35 complement(1536971..1537168) Haemophilus somnus 2336 6107228 YP_001784676.1 CDS infC NC_010519.1 1537267 1537746 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(1537267..1537746) Haemophilus somnus 2336 6107229 YP_001784677.1 CDS HSM_1357 NC_010519.1 1538170 1538943 D Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1538170..1538943 Haemophilus somnus 2336 6107230 YP_001784678.1 CDS HSM_1358 NC_010519.1 1539094 1540017 D with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1539094..1540017 Haemophilus somnus 2336 6107231 YP_001784679.1 CDS HSM_1359 NC_010519.1 1540062 1541393 R TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; KEGG: hso:HS_0880 folylpolyglutamate synthase; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase complement(1540062..1541393) Haemophilus somnus 2336 6107232 YP_001784680.1 CDS HSM_1360 NC_010519.1 1541383 1542282 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(1541383..1542282) Haemophilus somnus 2336 6107233 YP_001784681.1 CDS HSM_1361 NC_010519.1 1542365 1543309 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(1542365..1543309) Haemophilus somnus 2336 6107235 YP_001784682.1 CDS HSM_1362 NC_010519.1 1543414 1544241 R PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: hso:HS_0883 TrpH protein; phosphotransferase domain-containing protein complement(1543414..1544241) Haemophilus somnus 2336 6107236 YP_001784683.1 CDS pepN NC_010519.1 1544321 1546930 R TIGRFAM: aminopeptidase N; PFAM: peptidase M1 membrane alanine aminopeptidase; KEGG: hso:HS_0884 aminopeptidase N; aminopeptidase N complement(1544321..1546930) Haemophilus somnus 2336 6107237 YP_001784684.1 CDS HSM_1364 NC_010519.1 1547039 1549498 R TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; KEGG: hso:HS_0885 glycogen phosphorylase; glycogen/starch/alpha-glucan phosphorylase complement(1547039..1549498) Haemophilus somnus 2336 6107238 YP_001784685.1 CDS glgA NC_010519.1 1549620 1551080 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(1549620..1551080) Haemophilus somnus 2336 6107239 YP_001784686.1 CDS glgC NC_010519.1 1551129 1552439 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(1551129..1552439) Haemophilus somnus 2336 6107240 YP_001784687.1 CDS HSM_1367 NC_010519.1 1552498 1554480 R TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: hso:HS_0888 glycogen operon protein; glycogen debranching protein GlgX complement(1552498..1554480) Haemophilus somnus 2336 6107241 YP_001784688.1 CDS HSM_1368 NC_010519.1 1554506 1556953 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein complement(1554506..1556953) Haemophilus somnus 2336 6107242 YP_001784689.1 CDS HSM_1369 NC_010519.1 1556965 1559064 R TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77; KEGG: hso:HS_0890 4-alpha-glucanotransferase; 4-alpha-glucanotransferase complement(1556965..1559064) Haemophilus somnus 2336 6107243 YP_001784690.1 CDS HSM_1370 NC_010519.1 1559174 1559641 R PFAM: protein of unknown function UPF0153; KEGG: hso:HS_0891 hypothetical protein; hypothetical protein complement(1559174..1559641) Haemophilus somnus 2336 6107244 YP_001784691.1 CDS HSM_1371 NC_010519.1 1559731 1562514 R PFAM: peptidase M16 domain protein; KEGG: hso:HS_0892 zinc protease; peptidase M16 domain-containing protein complement(1559731..1562514) Haemophilus somnus 2336 6107246 YP_001784692.1 CDS HSM_1372 NC_010519.1 1562514 1564901 R PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0894 hypothetical protein; TonB-dependent receptor complement(1562514..1564901) Haemophilus somnus 2336 6107247 YP_001784693.1 CDS HSM_1373 NC_010519.1 1565097 1566764 R catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase complement(1565097..1566764) Haemophilus somnus 2336 6107248 YP_001784694.1 CDS HSM_1374 NC_010519.1 1566960 1567913 D PFAM: protein of unknown function UPF0052 and CofD; KEGG: hso:HS_0896 hypothetical protein; hypothetical protein 1566960..1567913 Haemophilus somnus 2336 6107249 YP_001784695.1 CDS HSM_1375 NC_010519.1 1567900 1570989 R PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: hso:HS_0897 tetrathionate reductase, subunit A; molybdopterin oxidoreductase complement(1567900..1570989) Haemophilus somnus 2336 6107250 YP_001784696.1 CDS HSM_1376 NC_010519.1 1570982 1572010 R PFAM: polysulphide reductase NrfD; KEGG: hso:HS_0898 tetrathionate reductase, subunit C; polysulfide reductase NrfD complement(1570982..1572010) Haemophilus somnus 2336 6107251 YP_001784697.1 CDS HSM_1377 NC_010519.1 1572007 1572744 R PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: hso:HS_0899 tetrathionate reductase, subunit B; 4Fe-4S ferredoxin complement(1572007..1572744) Haemophilus somnus 2336 6107252 YP_001784698.1 CDS HSM_1378 NC_010519.1 1572996 1574660 D PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: hso:HS_0900 sensor kinase; histidine kinase 1572996..1574660 Haemophilus somnus 2336 6107253 YP_001784699.1 CDS HSM_1379 NC_010519.1 1574662 1575252 D PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: hso:HS_0901 two component response regulator; response regulator receiver protein 1574662..1575252 Haemophilus somnus 2336 6107254 YP_001784700.1 CDS HSM_1380 NC_010519.1 1575344 1576798 R Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI complement(1575344..1576798) Haemophilus somnus 2336 6107255 YP_001784701.1 CDS HSM_1381 NC_010519.1 1576988 1577239 D TIGRFAM: exodeoxyribonuclease VII small subunit; PFAM: exonuclease VII small subunit; KEGG: hso:HS_0903 exodeoxyribonuclease VII small subunit; exodeoxyribonuclease VII small subunit 1576988..1577239 Haemophilus somnus 2336 6107257 YP_001784702.1 CDS HSM_1382 NC_010519.1 1577255 1578145 D PFAM: polyprenyl synthetase; KEGG: hso:HS_0904 farnesyl-diphosphate synthase; polyprenyl synthetase 1577255..1578145 Haemophilus somnus 2336 6107258 YP_001784703.1 CDS HSM_1383 NC_010519.1 1578178 1580031 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1578178..1580031 Haemophilus somnus 2336 6107259 YP_001784704.1 CDS HSM_1384 NC_010519.1 1580289 1581197 D PFAM: protein of unknown function DUF340 membrane; KEGG: hso:HS_0906 permease; hypothetical protein 1580289..1581197 Haemophilus somnus 2336 6107260 YP_001784705.1 CDS HSM_1385 NC_010519.1 1581483 1581902 D catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1581483..1581902 Haemophilus somnus 2336 6107261 YP_001784706.1 CDS HSM_1386 NC_010519.1 1582016 1583881 R TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: hso:HS_0908 protease IV family; signal peptide peptidase SppA, 67K type complement(1582016..1583881) Haemophilus somnus 2336 6107262 YP_001784707.1 CDS HSM_1387 NC_010519.1 1584009 1584563 D PFAM: nitroreductase; KEGG: hso:HS_0909 nitroreductase family protein; nitroreductase 1584009..1584563 Haemophilus somnus 2336 6107263 YP_001784708.1 CDS folE NC_010519.1 1584629 1585285 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(1584629..1585285) Haemophilus somnus 2336 6107264 YP_001784709.1 CDS HSM_1389 NC_010519.1 1585432 1586646 D TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: hso:HS_0911 molybdopterin biosynthesis protein; molybdenum cofactor synthesis domain-containing protein 1585432..1586646 Haemophilus somnus 2336 6107265 YP_001784710.1 CDS HSM_1390 NC_010519.1 1586654 1587382 D ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 1586654..1587382 Haemophilus somnus 2336 6107266 YP_001784711.1 CDS HSM_1391 NC_010519.1 1587455 1588087 R TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase; KEGG: hso:HS_0913 phosphoribosylglycinamide formyltransferase; phosphoribosylglycinamide formyltransferase complement(1587455..1588087) Haemophilus somnus 2336 6107268 YP_001784712.1 CDS HSM_1392 NC_010519.1 1588300 1590906 R catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I complement(1588300..1590906) Haemophilus somnus 2336 6107269 YP_001784713.1 CDS HSM_1393 NC_010519.1 1591187 1591798 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(1591187..1591798) Haemophilus somnus 2336 6107270 YP_001784714.1 CDS HSM_1394 NC_010519.1 1591764 1593278 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(1591764..1593278) Haemophilus somnus 2336 6107271 YP_001784715.1 CDS HSM_1395 NC_010519.1 1593291 1593791 R PFAM: colicin V production protein; KEGG: hso:HS_0917 colicin V production protein; colicin V production protein complement(1593291..1593791) Haemophilus somnus 2336 6107272 YP_001784716.1 CDS HSM_1396 NC_010519.1 1594486 1595421 D TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: hso:HS_0918 polysialic acid capsule expression protein, KpsF/GutQ family protein; KpsF/GutQ family protein 1594486..1595421 Haemophilus somnus 2336 6107273 YP_001784717.1 CDS HSM_1397 NC_010519.1 1595426 1595977 D TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: hso:HS_0919 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 1595426..1595977 Haemophilus somnus 2336 6107274 YP_001784718.1 CDS HSM_1398 NC_010519.1 1596315 1596800 D PFAM: ferritin; KEGG: hso:HS_0920 ferritin like protein 1; ferroxidase 1596315..1596800 Haemophilus somnus 2336 6107275 YP_001784719.1 CDS HSM_1399 NC_010519.1 1596817 1597314 D PFAM: ferritin; KEGG: hso:HS_0921 ferritin like protein 2; ferroxidase 1596817..1597314 Haemophilus somnus 2336 6107276 YP_001784720.1 CDS HSM_1400 NC_010519.1 1597536 1598291 R PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: hso:HS_0922 transcriptional regulator, DeoR family; DeoR family transcriptional regulator complement(1597536..1598291) Haemophilus somnus 2336 6107277 YP_001784721.1 CDS HSM_1401 NC_010519.1 1598395 1599624 R KEGG: hso:HS_0923 hypothetical protein; hypothetical protein complement(1598395..1599624) Haemophilus somnus 2336 6107280 YP_001784722.1 CDS HSM_1402 NC_010519.1 1599621 1600619 R transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease complement(1599621..1600619) Haemophilus somnus 2336 6107281 YP_001784723.1 CDS pdxA NC_010519.1 1600630 1601631 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(1600630..1601631) Haemophilus somnus 2336 6107282 YP_001784724.1 CDS HSM_1404 NC_010519.1 1602051 1603415 D catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase 1602051..1603415 Haemophilus somnus 2336 6107283 YP_001784725.1 CDS HSM_1405 NC_010519.1 1603505 1605040 D PFAM: pyridoxal-dependent decarboxylase; KEGG: hso:HS_0927 L-2,4-diaminobutyrate decarboxylase; pyridoxal-dependent decarboxylase 1603505..1605040 Haemophilus somnus 2336 6107284 YP_001784726.1 CDS HSM_1406 NC_010519.1 1605157 1607181 R TIGRFAM: exodeoxyribonuclease V, subunit alpha; KEGG: hso:HS_0928 exodeoxyribonuclease V, alpha chain; exodeoxyribonuclease V subunit alpha complement(1605157..1607181) Haemophilus somnus 2336 6107285 YP_001784727.1 CDS HSM_1407 NC_010519.1 1607181 1610831 R TIGRFAM: exodeoxyribonuclease V subunit beta; PFAM: UvrD/REP helicase; KEGG: hso:HS_0929 exodeoxyribonuclease V, beta chain; exodeoxyribonuclease V subunit beta complement(1607181..1610831) Haemophilus somnus 2336 6107286 YP_001784728.1 CDS HSM_1408 NC_010519.1 1610942 1611808 R metalloprotease; heat shock protein HtpX complement(1610942..1611808) Haemophilus somnus 2336 6107287 YP_001784729.1 CDS HSM_1409 NC_010519.1 1611891 1612955 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(1611891..1612955) Haemophilus somnus 2336 6107288 YP_001784730.1 CDS HSM_1410 NC_010519.1 1613276 1614229 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1613276..1614229 Haemophilus somnus 2336 6107289 YP_001784731.1 CDS HSM_1411 NC_010519.1 1614298 1615158 D catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1614298..1615158 Haemophilus somnus 2336 6107291 YP_001784732.1 CDS HSM_1412 NC_010519.1 1615233 1616516 D TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; protein of unkown function DUF1946 PP-loop ATpase; KEGG: hso:HS_0934 cell-cycle protein; tRNA(Ile)-lysidine synthetase 1615233..1616516 Haemophilus somnus 2336 6107292 YP_001784733.1 CDS pgi NC_010519.1 1616564 1618213 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(1616564..1618213) Haemophilus somnus 2336 6107293 YP_001784734.1 CDS alr NC_010519.1 1618241 1619320 R converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase complement(1618241..1619320) Haemophilus somnus 2336 6107294 YP_001784735.1 CDS HSM_1415 NC_010519.1 1619337 1620755 R unwinds double stranded DNA; replicative DNA helicase complement(1619337..1620755) Haemophilus somnus 2336 6107295 YP_001784736.1 CDS HSM_1416 NC_010519.1 1620907 1621986 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1620907..1621986) Haemophilus somnus 2336 6107296 YP_001784737.1 CDS HSM_1417 NC_010519.1 1622093 1623343 R part of the ATP-dependent transporter LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE complement(1622093..1623343) Haemophilus somnus 2336 6107297 YP_001784738.1 CDS HSM_1418 NC_010519.1 1623340 1624023 R TIGRFAM: lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0943 lipoprotein releasing system, ATP-binding protein; lipoprotein releasing system, ATP-binding protein complement(1623340..1624023) Haemophilus somnus 2336 6107298 YP_001784739.1 CDS HSM_1419 NC_010519.1 1624044 1625234 R TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: hso:HS_0944 lipoprotein releasing system, transmembrane protein; LolC/E family lipoprotein releasing system, transmembrane protein complement(1624044..1625234) Haemophilus somnus 2336 6107299 YP_001784740.1 CDS HSM_1420 NC_010519.1 1625404 1626345 R Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; glycerate dehydrogenase complement(1625404..1626345) Haemophilus somnus 2336 6107300 YP_001784741.1 CDS HSM_1421 NC_010519.1 1626457 1627311 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(1626457..1627311) Haemophilus somnus 2336 6107302 YP_001784742.1 CDS HSM_1422 NC_010519.1 1627325 1628119 R KEGG: hso:HS_0947 hypothetical protein; hypothetical protein complement(1627325..1628119) Haemophilus somnus 2336 6107303 YP_001784743.1 CDS HSM_1423 NC_010519.1 1628103 1629008 R TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: hso:HS_0948 peptide release factor glutamine N(5)-methylase; HemK family modification methylase complement(1628103..1629008) Haemophilus somnus 2336 6107304 YP_001784744.1 CDS HSM_1424 NC_010519.1 1629023 1629514 R PFAM: RDD domain containing protein; KEGG: hso:HS_0949 hypothetical protein; RDD domain-containing protein complement(1629023..1629514) Haemophilus somnus 2336 6107305 YP_001784745.1 CDS prfA NC_010519.1 1629566 1630648 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(1629566..1630648) Haemophilus somnus 2336 6107306 YP_001784746.1 CDS HSM_1426 NC_010519.1 1630686 1631588 R PFAM: Lipooligosaccharide sialyltransferase; KEGG: hdu:HD0686 lipooligosaccharide sialyltransferase; lipooligosaccharide sialyltransferase complement(1630686..1631588) Haemophilus somnus 2336 6107307 YP_001784747.1 CDS HSM_1427 NC_010519.1 1631712 1632173 R PFAM: 17 kDa surface antigen; KEGG: hso:HS_0952 outer membrane lipoprotein pcp precursor; 17 kDa surface antigen complement(1631712..1632173) Haemophilus somnus 2336 6107308 YP_001784748.1 CDS HSM_1428 NC_010519.1 1632197 1632520 R KEGG: hso:HS_0953 hypothetical protein; hypothetical protein complement(1632197..1632520) Haemophilus somnus 2336 6107309 YP_001784749.1 CDS HSM_1429 NC_010519.1 1632526 1633113 R PFAM: protein of unknown function DUF991; KEGG: hso:HS_0954 hypothetical protein; hypothetical protein complement(1632526..1633113) Haemophilus somnus 2336 6107310 YP_001784750.1 CDS argS NC_010519.1 1633197 1634930 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1633197..1634930 Haemophilus somnus 2336 6107311 YP_001784751.1 CDS HSM_1431 NC_010519.1 1635004 1635876 R TIGRFAM: succinyl-CoA synthetase, subunit alpha; PFAM: CoA-binding protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: hso:HS_0956 succinyl-CoA synthetase, subunit alpha; succinyl-CoA synthetase subunit alpha complement(1635004..1635876) Haemophilus somnus 2336 6107313 YP_001784752.1 CDS sucC NC_010519.1 1635876 1637045 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(1635876..1637045) Haemophilus somnus 2336 6107314 YP_001784753.1 CDS HSM_1433 NC_010519.1 1637099 1638322 R TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: hso:HS_0958 dihydrolipoamide succinyltransferase; 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase complement(1637099..1638322) Haemophilus somnus 2336 6107315 YP_001784754.1 CDS sucA NC_010519.1 1638411 1641206 R SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component complement(1638411..1641206) Haemophilus somnus 2336 6107316 YP_001784755.1 CDS HSM_1435 NC_010519.1 1641552 1642835 D TIGRFAM: citrate synthase I; PFAM: citrate synthase; KEGG: hso:HS_0960 citrate synthase; citrate synthase I 1641552..1642835 Haemophilus somnus 2336 6107317 YP_001784756.1 CDS nrdB NC_010519.1 1642973 1644103 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 1642973..1644103 Haemophilus somnus 2336 6107318 YP_001784757.1 CDS HSM_1437 NC_010519.1 1644169 1644426 D PFAM: ferredoxin; KEGG: hso:HS_0962 ferredoxin 2Fe-2S type; ferredoxin 1644169..1644426 Haemophilus somnus 2336 6107319 YP_001784758.1 CDS nhaA NC_010519.1 1644480 1645676 R exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter complement(1644480..1645676) Haemophilus somnus 2336 6107320 YP_001784759.1 CDS HSM_1439 NC_010519.1 1645854 1647206 R dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein complement(1645854..1647206) Haemophilus somnus 2336 6107321 YP_001784760.1 CDS HSM_1440 NC_010519.1 1647368 1647871 D PFAM: nuclease (SNase domain protein); KEGG: hso:HS_0966 nuclease; nuclease 1647368..1647871 Haemophilus somnus 2336 6107322 YP_001784761.1 CDS HSM_1441 NC_010519.1 1647861 1649060 D PFAM: aminotransferase class V; KEGG: hso:HS_0967 cysteine desulfurase, aminotransferase, class V; class V aminotransferase 1647861..1649060 Haemophilus somnus 2336 6107324 YP_001784762.1 CDS HSM_1442 NC_010519.1 1649057 1649434 D PFAM: Fe-S metabolism associated SufE; KEGG: hso:HS_0968 conserved hypothetical protein; Fe-S metabolism associated SufE 1649057..1649434 Haemophilus somnus 2336 6107325 YP_001784763.1 CDS HSM_1443 NC_010519.1 1650043 1650309 D hypothetical protein 1650043..1650309 Haemophilus somnus 2336 6107326 YP_001784764.1 CDS HSM_1444 NC_010519.1 1650254 1650916 D PFAM: filamentation induced by cAMP protein Fic; KEGG: xft:PD1006 cell filamentation protein; filamentation induced by cAMP protein fic 1650254..1650916 Haemophilus somnus 2336 6107327 YP_001784765.1 CDS HSM_1445 NC_010519.1 1651203 1651496 D TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; KEGG: hso:HS_0969 RelB protein; addiction module antitoxin 1651203..1651496 Haemophilus somnus 2336 6107328 YP_001784766.1 CDS HSM_1446 NC_010519.1 1651489 1651761 D TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: hso:HS_0970 hypothetical protein; addiction module antitoxin 1651489..1651761 Haemophilus somnus 2336 6107329 YP_001784767.1 CDS HSM_1447 NC_010519.1 1651846 1652988 R PFAM: porin Gram-negative type; KEGG: hso:HS_0971 outer membrane protein, OmpH family; porin complement(1651846..1652988) Haemophilus somnus 2336 6107330 YP_001784768.1 CDS HSM_1448 NC_010519.1 1653426 1653707 D PFAM: virulence-associated protein D (VapD) conserved region; KEGG: rpc:RPC_2389 virulence-associated protein D; virulence-associated protein D (VapD) region 1653426..1653707 Haemophilus somnus 2336 6107331 YP_001784769.1 CDS HSM_1449 NC_010519.1 1653906 1654205 D PFAM: protein of unknown function DUF1778; KEGG: hin:HI0420 hypothetical protein; hypothetical protein 1653906..1654205 Haemophilus somnus 2336 6107332 YP_001784770.1 CDS HSM_1450 NC_010519.1 1654195 1654701 D PFAM: GCN5-related N-acetyltransferase; KEGG: hso:HS_1675 histone acetyltransferase; N-acetyltransferase GCN5 1654195..1654701 Haemophilus somnus 2336 6107333 YP_001784771.1 CDS HSM_1451 NC_010519.1 1654725 1655921 R PFAM: hypothetical protein; KEGG: hso:HS_0973 hypothetical protein; hypothetical protein complement(1654725..1655921) Haemophilus somnus 2336 6107335 YP_001784772.1 CDS HSM_1452 NC_010519.1 1655931 1656215 R PFAM: protein of unknown function DUF1049; KEGG: hso:HS_0974 hypothetical protein; hypothetical protein complement(1655931..1656215) Haemophilus somnus 2336 6107336 YP_001784773.1 CDS ihfB NC_010519.1 1656335 1656619 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta complement(1656335..1656619) Haemophilus somnus 2336 6107337 YP_001784774.1 CDS rpsA NC_010519.1 1656683 1658326 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(1656683..1658326) Haemophilus somnus 2336 6107338 YP_001784775.1 CDS HSM_1455 NC_010519.1 1658399 1659112 R TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: hso:HS_0977 cytidylate kinase 1; cytidylate kinase complement(1658399..1659112) Haemophilus somnus 2336 6107339 YP_001784776.1 CDS lpxD NC_010519.1 1659165 1660190 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(1659165..1660190) Haemophilus somnus 2336 6107340 YP_001784777.1 CDS HSM_1457 NC_010519.1 1660190 1660774 R PFAM: outer membrane chaperone Skp (OmpH); KEGG: hso:HS_0979 outer membrane protein; outer membrane chaperone Skp complement(1660190..1660774) Haemophilus somnus 2336 6107341 YP_001784778.1 CDS HSM_1458 NC_010519.1 1660871 1663300 R PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: hso:HS_0980 surface antigen; surface antigen (D15) complement(1660871..1663300) Haemophilus somnus 2336 6107342 YP_001784779.1 CDS HSM_1459 NC_010519.1 1663369 1664700 R TIGRFAM: membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: hso:HS_0981 zinc metalloprotease; membrane-associated zinc metalloprotease complement(1663369..1664700) Haemophilus somnus 2336 6107343 YP_001784780.1 CDS HSM_1460 NC_010519.1 1664709 1665572 R PFAM: phosphatidate cytidylyltransferase; KEGG: hso:HS_0982 phosphatidate cytidylyltransferase; phosphatidate cytidylyltransferase complement(1664709..1665572) Haemophilus somnus 2336 6107344 YP_001784781.1 CDS HSM_1461 NC_010519.1 1665585 1666310 R TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; KEGG: hso:HS_0983 undecaprenyl pyrophosphate synthase; undecaprenyl diphosphate synthase complement(1665585..1666310) Haemophilus somnus 2336 6107346 YP_001784782.1 CDS HSM_1462 NC_010519.1 1666493 1666999 R KEGG: hso:HS_0984 hypothetical protein; hypothetical protein complement(1666493..1666999) Haemophilus somnus 2336 6107347 YP_001784783.1 CDS HSM_1463 NC_010519.1 1667001 1668209 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(1667001..1668209) Haemophilus somnus 2336 6107348 YP_001784784.1 CDS frr NC_010519.1 1668280 1668837 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(1668280..1668837) Haemophilus somnus 2336 6107349 YP_001784785.1 CDS pyrH NC_010519.1 1668891 1669607 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(1668891..1669607) Haemophilus somnus 2336 6107350 YP_001784786.1 CDS HSM_1466 NC_010519.1 1669706 1670014 R KEGG: hso:HS_0988 hypothetical protein; hypothetical protein complement(1669706..1670014) Haemophilus somnus 2336 6107351 YP_001784787.1 CDS HSM_1467 NC_010519.1 1670115 1670414 D KEGG: hso:HS_0989 hypothetical protein; hypothetical protein 1670115..1670414 Haemophilus somnus 2336 6107352 YP_001784788.1 CDS HSM_1468 NC_010519.1 1670493 1673189 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1670493..1673189 Haemophilus somnus 2336 6107353 YP_001784789.1 CDS HSM_1469 NC_010519.1 1673236 1673634 D TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: hso:HS_0991 7,8-dihydro-8-oxoguanine-triphosphatase; mutator MutT protein 1673236..1673634 Haemophilus somnus 2336 6107354 YP_001784790.1 CDS HSM_1470 NC_010519.1 1673702 1677613 R involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA complement(1673702..1677613) Haemophilus somnus 2336 6107355 YP_001784791.1 CDS HSM_1471 NC_010519.1 1677660 1678115 R PFAM: protein of unknown function DUF441; KEGG: hso:HS_0993 permease; hypothetical protein complement(1677660..1678115) Haemophilus somnus 2336 6107357 YP_001784792.1 CDS HSM_1472 NC_010519.1 1678428 1681067 D catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 1678428..1681067 Haemophilus somnus 2336 6107358 YP_001784793.1 CDS HSM_1473 NC_010519.1 1681170 1681493 D highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1681170..1681493 Haemophilus somnus 2336 6107359 YP_001784794.1 CDS HSM_1474 NC_010519.1 1681650 1682597 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1681650..1682597) Haemophilus somnus 2336 6107360 YP_001784795.1 CDS ipk NC_010519.1 1682605 1683546 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1682605..1683546) Haemophilus somnus 2336 6107361 YP_001784796.1 CDS lolB NC_010519.1 1683546 1684175 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB complement(1683546..1684175) Haemophilus somnus 2336 6107362 YP_001784797.1 CDS HSM_1477 NC_010519.1 1684353 1684622 D KEGG: hso:HS_0999 hypothetical protein; hypothetical protein 1684353..1684622 Haemophilus somnus 2336 6107363 YP_001784798.1 CDS greA NC_010519.1 1684901 1685377 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1684901..1685377 Haemophilus somnus 2336 6107364 YP_001784799.1 CDS HSM_1479 NC_010519.1 1685432 1685728 R PFAM: protein of unknown function UPF0044; KEGG: hso:HS_1001 conserved hypothetical protein; hypothetical protein complement(1685432..1685728) Haemophilus somnus 2336 6107365 YP_001784800.1 CDS HSM_1480 NC_010519.1 1685845 1686195 R TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: hso:HS_1002 arsenate reductase; arsenate reductase complement(1685845..1686195) Haemophilus somnus 2336 6107366 YP_001784801.1 CDS HSM_1481 NC_010519.1 1686281 1687333 D PFAM: protein of unknown function UPF0118; KEGG: hso:HS_1003 permease; hypothetical protein 1686281..1687333 Haemophilus somnus 2336 6107368 YP_001784802.1 CDS HSM_1482 NC_010519.1 1687353 1688792 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 1687353..1688792 Haemophilus somnus 2336 6107369 YP_001784803.1 CDS HSM_1483 NC_010519.1 1688789 1688941 D KEGG: hit:NTHI0339 hypothetical protein; hypothetical protein 1688789..1688941 Haemophilus somnus 2336 6107370 YP_001784804.1 CDS HSM_1484 NC_010519.1 1689542 1696081 D PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1085 large adhesin; YadA domain-containing protein 1689542..1696081 Haemophilus somnus 2336 6107371 YP_001784805.1 CDS HSM_1485 NC_010519.1 1696210 1697193 R KEGG: hso:HS_1010 biotin synthetase; TIGRFAM: biotin synthase; PFAM: radical SAM protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB; biotin synthase complement(1696210..1697193) Haemophilus somnus 2336 6107372 YP_001784806.1 CDS HSM_1486 NC_010519.1 1697225 1697869 R TIGRFAM: ABC transporter ATPase, ThiQ subfamily; PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1011 thiamine ABC transporter ATP-binding protein; ABC transporter ATP-binding protein complement(1697225..1697869) Haemophilus somnus 2336 6107373 YP_001784807.1 CDS thiP NC_010519.1 1697862 1699466 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(1697862..1699466) Haemophilus somnus 2336 6107374 YP_001784808.1 CDS HSM_1488 NC_010519.1 1699468 1700484 R TIGRFAM: ABC transporter periplasmic binding protein, thiB subfamily; thiamine ABC transporter periplasmic binding protein; KEGG: hso:HS_1013 thiamine ABC transporter periplasmic-binding protein; thiamine ABC transporter periplasmic binding protein complement(1699468..1700484) Haemophilus somnus 2336 6107375 YP_001784809.1 CDS HSM_1489 NC_010519.1 1701024 1713311 R TIGRFAM: cysteine protease domain, YopT-type; filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: filamentation induced by cAMP protein Fic; peptidase C58 Yersinia/Haemophilus virulence surface antigen; Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: pmu:PM0059 virulence factor, filamentous hemaglutinin; cysteine protease complement(1701024..1713311) Haemophilus somnus 2336 6107376 YP_001784810.1 CDS HSM_1490 NC_010519.1 1713336 1715096 R PFAM: Hemolysin activator HlyB domain protein; polypeptide-transport-associated domain protein ShlB-type; KEGG: pmu:PM0056 hemolysin accessory protein; polypeptide-transport-associated domain-containing protein complement(1713336..1715096) Haemophilus somnus 2336 6107377 YP_001784811.1 CDS HSM_1491 NC_010519.1 1715441 1716799 D PFAM: citrate transporter; Na? antiporter NhaC; KEGG: hso:HS_1014 conserved hypothetical protein; hypothetical protein 1715441..1716799 Haemophilus somnus 2336 6107379 YP_001784812.1 CDS HSM_1492 NC_010519.1 1716847 1717440 D KEGG: hso:HS_1015 hypothetical protein; hypothetical protein 1716847..1717440 Haemophilus somnus 2336 6107380 YP_001784813.1 CDS HSM_1493 NC_010519.1 1717475 1717648 R KEGG: hso:HS_1015a hypothetical protein; hypothetical protein complement(1717475..1717648) Haemophilus somnus 2336 6107381 YP_001784814.1 CDS HSM_1494 NC_010519.1 1717649 1718221 R Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor complement(1717649..1718221) Haemophilus somnus 2336 6107382 YP_001784815.1 CDS HSM_1495 NC_010519.1 1718307 1719260 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 1718307..1719260 Haemophilus somnus 2336 6107383 YP_001784816.1 CDS HSM_1496 NC_010519.1 1719260 1719859 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 1719260..1719859 Haemophilus somnus 2336 6107384 YP_001784817.1 CDS HSM_1497 NC_010519.1 1719961 1721226 R KEGG: hso:HS_1019 permease; permease complement(1719961..1721226) Haemophilus somnus 2336 6107385 YP_001784818.1 CDS rlmL NC_010519.1 1722059 1724215 R catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase complement(1722059..1724215) Haemophilus somnus 2336 6108894 YP_001784819.1 CDS HSM_1499 NC_010519.1 1724261 1726051 R involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease complement(1724261..1726051) Haemophilus somnus 2336 6107387 YP_001784820.1 CDS HSM_1500 NC_010519.1 1726061 1728439 R TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase; ComEC/Rec2-related protein; KEGG: hso:HS_1022 recombination protein 2; DNA internalization-related competence protein ComEC/Rec2 complement(1726061..1728439) Haemophilus somnus 2336 6107388 YP_001784821.1 CDS HSM_1501 NC_010519.1 1728786 1729223 D TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: hso:HS_1023 DnaK suppressor protein; TraR/DksA family transcriptional regulator 1728786..1729223 Haemophilus somnus 2336 6107391 YP_001784822.1 CDS HSM_1502 NC_010519.1 1729525 1730898 D TIGRFAM: poly(A) polymerase; PFAM: polynucleotide adenylyltransferase region; KEGG: hso:HS_1024 poly(A) polymerase; poly(A) polymerase 1729525..1730898 Haemophilus somnus 2336 6107392 YP_001784823.1 CDS HSM_1503 NC_010519.1 1730895 1731371 D TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: hso:HS_1025 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 1730895..1731371 Haemophilus somnus 2336 6107393 YP_001784824.1 CDS nagA NC_010519.1 1731469 1732617 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(1731469..1732617) Haemophilus somnus 2336 6107394 YP_001784825.1 CDS nagB NC_010519.1 1732630 1733436 R catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(1732630..1733436) Haemophilus somnus 2336 6107395 YP_001784826.1 CDS HSM_1506 NC_010519.1 1733668 1734120 R PFAM: molybdopterin biosynthesis MoaE protein; KEGG: hso:HS_1028 molybdopterin biosynthesis protein, E chain; molybdopterin biosynthesis MoaE protein complement(1733668..1734120) Haemophilus somnus 2336 6107396 YP_001784827.1 CDS moaD NC_010519.1 1734121 1734366 R catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit complement(1734121..1734366) Haemophilus somnus 2336 6107397 YP_001784828.1 CDS HSM_1508 NC_010519.1 1734388 1734864 R TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; KEGG: hso:HS_1030 molybdenum cofactor biosynthesis protein, C chain; molybdenum cofactor biosynthesis protein C complement(1734388..1734864) Haemophilus somnus 2336 6107398 YP_001784829.1 CDS moaA NC_010519.1 1734874 1735890 R together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A complement(1734874..1735890) Haemophilus somnus 2336 6107399 YP_001784830.1 CDS HSM_1510 NC_010519.1 1736162 1737163 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1736162..1737163 Haemophilus somnus 2336 6107400 YP_001784831.1 CDS cysB NC_010519.1 1737214 1738185 R LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; CysB family transcripitonal regulator complement(1737214..1738185) Haemophilus somnus 2336 6107402 YP_001784832.1 CDS HSM_1512 NC_010519.1 1738247 1738573 R TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: hso:HS_1034 glutaredoxin-like protein; glutaredoxin-like protein complement(1738247..1738573) Haemophilus somnus 2336 6107403 YP_001784833.1 CDS HSM_1513 NC_010519.1 1738675 1739703 R PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: hso:HS_1035 hemagglutinin antigen; OmpA domain-containing protein complement(1738675..1739703) Haemophilus somnus 2336 6107404 YP_001784834.1 CDS HSM_1514 NC_010519.1 1739846 1741222 R PFAM: peptidase M23B; KEGG: hso:HS_1036 metalloprotease; peptidase M23B complement(1739846..1741222) Haemophilus somnus 2336 6107405 YP_001784835.1 CDS HSM_1515 NC_010519.1 1741411 1742205 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1037 high-affinity zinc uptake system, ATP-binding protein; ABC transporter 1741411..1742205 Haemophilus somnus 2336 6107406 YP_001784836.1 CDS HSM_1516 NC_010519.1 1742215 1743000 D PFAM: ABC transporter; KEGG: hso:HS_1038 high-affinity zinc uptake system, membrane protein; ABC transporter 1742215..1743000 Haemophilus somnus 2336 6107407 YP_001784837.1 CDS HSM_1517 NC_010519.1 1743073 1744512 R TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: hso:HS_1039 amino acid carrier protein; amino acid carrier protein complement(1743073..1744512) Haemophilus somnus 2336 6107408 YP_001784838.1 CDS HSM_1518 NC_010519.1 1744684 1745601 R catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase complement(1744684..1745601) Haemophilus somnus 2336 6107409 YP_001784839.1 CDS HSM_1519 NC_010519.1 1745637 1746374 R PFAM: phosphoesterase PA-phosphatase related; KEGG: hso:HS_1042 phosphatidylglycerophosphatase B; phosphatidylglycerophosphatase complement(1745637..1746374) Haemophilus somnus 2336 6107410 YP_001784840.1 CDS ribA NC_010519.1 1746467 1747117 D catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1746467..1747117 Haemophilus somnus 2336 6107411 YP_001784841.1 CDS HSM_1521 NC_010519.1 1747439 1748563 R KEGG: hdu:HD1689 transposase; transposase complement(1747439..1748563) Haemophilus somnus 2336 6107413 YP_001784842.1 CDS HSM_1522 NC_010519.1 1750248 1750766 D hypothetical protein 1750248..1750766 Haemophilus somnus 2336 6107414 YP_001784843.1 CDS HSM_1523 NC_010519.1 1750792 1751304 D KEGG: dde:Dde_1416 hypothetical protein; hypothetical protein 1750792..1751304 Haemophilus somnus 2336 6107415 YP_001784844.1 CDS HSM_1524 NC_010519.1 1751470 1752072 D hypothetical protein 1751470..1752072 Haemophilus somnus 2336 6107416 YP_001784845.1 CDS HSM_1525 NC_010519.1 1752082 1752618 D KEGG: plu:plu0643 hypothetical protein; hypothetical protein 1752082..1752618 Haemophilus somnus 2336 6107417 YP_001784846.1 CDS HSM_1526 NC_010519.1 1752864 1753844 D KEGG: plu:plu0643 hypothetical protein; hypothetical protein 1752864..1753844 Haemophilus somnus 2336 6107418 YP_001784847.1 CDS HSM_1527 NC_010519.1 1754084 1754551 R KEGG: hdu:HD1698 hypothetical protein; hypothetical protein complement(1754084..1754551) Haemophilus somnus 2336 6107419 YP_001784848.1 CDS HSM_1528 NC_010519.1 1754713 1757808 D PFAM: FAD linked oxidase; KEGG: hso:HS_1044 conserved hypothetical protein; FAD linked oxidase domain-containing protein 1754713..1757808 Haemophilus somnus 2336 6107420 YP_001784849.1 CDS HSM_1529 NC_010519.1 1757825 1758247 D PFAM: thioesterase superfamily protein; KEGG: hso:HS_1045 hypothetical protein; thioesterase superfamily protein 1757825..1758247 Haemophilus somnus 2336 6107421 YP_001784850.1 CDS HSM_1530 NC_010519.1 1758306 1758857 D KEGG: hso:HS_1046 permease; permease 1758306..1758857 Haemophilus somnus 2336 6107422 YP_001784851.1 CDS hemH NC_010519.1 1758698 1759828 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1758698..1759828 Haemophilus somnus 2336 6107424 YP_001784852.1 CDS HSM_1532 NC_010519.1 1759971 1761017 D PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_1048 spermidine/putrescine-binding periplasmic protein; extracellular solute-binding protein 1759971..1761017 Haemophilus somnus 2336 6107425 YP_001784853.1 CDS HSM_1533 NC_010519.1 1761123 1762169 R TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: hso:HS_1049 protease DegS precursor; periplasmic serine protease DegS complement(1761123..1762169) Haemophilus somnus 2336 6107426 YP_001784854.1 CDS HSM_1534 NC_010519.1 1762189 1763319 R TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; KEGG: hso:HS_1050 riboflavin biosynthesis protein; riboflavin biosynthesis protein RibD complement(1762189..1763319) Haemophilus somnus 2336 6107427 YP_001784855.1 CDS nrdR NC_010519.1 1763322 1763771 R PFAM: ATP-cone domain protein; KEGG: hso:HS_1051 conserved hypothetical protein; NrdR family transcripitonal regulator complement(1763322..1763771) Haemophilus somnus 2336 6107428 YP_001784856.1 CDS HSM_1536 NC_010519.1 1763921 1764250 R PFAM: branched-chain amino acid ABC transporter; KEGG: hso:HS_1052 branched-chain amino acid ABC transporterer; branched-chain amino acid ABC transporter complement(1763921..1764250) Haemophilus somnus 2336 6107429 YP_001784857.1 CDS HSM_1537 NC_010519.1 1764261 1764992 R PFAM: AzlC family protein; KEGG: hso:HS_1053 branched-chain amino acid ABC transporterer; AzlC family protein complement(1764261..1764992) Haemophilus somnus 2336 6107430 YP_001784858.1 CDS HSM_1538 NC_010519.1 1765000 1765926 R PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: hso:HS_1054 transcriptional regulator; LysR family transcriptional regulator complement(1765000..1765926) Haemophilus somnus 2336 6107431 YP_001784859.1 CDS HSM_1539 NC_010519.1 1766063 1766998 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(1766063..1766998) Haemophilus somnus 2336 6107432 YP_001784860.1 CDS HSM_1540 NC_010519.1 1767222 1767689 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 1767222..1767689 Haemophilus somnus 2336 6107433 YP_001784861.1 CDS HSM_1541 NC_010519.1 1767711 1768598 D PFAM: NAD-dependent epimerase/dehydratase; domain of unknown function DUF1731; KEGG: hso:HS_1057 conserved hypothetical protein; hypothetical protein 1767711..1768598 Haemophilus somnus 2336 6107435 YP_001784862.1 CDS HSM_1542 NC_010519.1 1768676 1775833 R PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790 large adhesin; YadA domain-containing protein complement(1768676..1775833) Haemophilus somnus 2336 6107436 YP_001784863.1 CDS HSM_1543 NC_010519.1 1776512 1777093 D TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: hso:HS_1059 electron transport complex protein; Na(+)-translocating NADH-quinone reductase subunit E 1776512..1777093 Haemophilus somnus 2336 6107437 YP_001784864.1 CDS HSM_1544 NC_010519.1 1777097 1777687 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transporter subunit RnfB 1777097..1777687 Haemophilus somnus 2336 6107438 YP_001784865.1 CDS HSM_1545 NC_010519.1 1777691 1779811 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transporter subunit RnfC 1777691..1779811 Haemophilus somnus 2336 6107439 YP_001784866.1 CDS rnfD NC_010519.1 1779828 1780919 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transporter subunit RnfD 1779828..1780919 Haemophilus somnus 2336 6107440 YP_001784867.1 CDS HSM_1547 NC_010519.1 1780916 1781539 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transporter subunit RnfG 1780916..1781539 Haemophilus somnus 2336 6107441 YP_001784868.1 CDS HSM_1548 NC_010519.1 1781536 1782252 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transporter subunit RsxE 1781536..1782252 Haemophilus somnus 2336 6107442 YP_001784869.1 CDS HSM_1549 NC_010519.1 1782249 1782884 D KEGG: hso:HS_1065 endonuclease III; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop; endonuclease III 1782249..1782884 Haemophilus somnus 2336 6107443 YP_001784870.1 CDS HSM_1550 NC_010519.1 1782919 1784283 D PFAM: sodium:neurotransmitter symporter; KEGG: hso:HS_1066 sodium-dependent transporter; sodium:neurotransmitter symporter 1782919..1784283 Haemophilus somnus 2336 6107444 YP_001784871.1 CDS HSM_1551 NC_010519.1 1784314 1784529 D hypothetical protein 1784314..1784529 Haemophilus somnus 2336 6107446 YP_001784872.1 CDS HSM_1552 NC_010519.1 1784493 1785083 D KEGG: hso:HS_1067 hypothetical protein; hypothetical protein 1784493..1785083 Haemophilus somnus 2336 6107447 YP_001784873.1 CDS HSM_1553 NC_010519.1 1785163 1787808 R PFAM: hypothetical protein; KEGG: hso:HS_1068 hypothetical protein; hypothetical protein complement(1785163..1787808) Haemophilus somnus 2336 6107448 YP_001784874.1 CDS HSM_1554 NC_010519.1 1787786 1789039 R TIGRFAM: integral membrane protein, PqiA family; PFAM: paraquat-inducible protein A; KEGG: hso:HS_1069 hypothetical protein; PqiA family integral membrane protein complement(1787786..1789039) Haemophilus somnus 2336 6107449 YP_001784875.1 CDS HSM_1555 NC_010519.1 1789251 1789886 D affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 1789251..1789886 Haemophilus somnus 2336 6107450 YP_001784876.1 CDS HSM_1556 NC_010519.1 1789966 1791993 D Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 1789966..1791993 Haemophilus somnus 2336 6107451 YP_001784877.1 CDS HSM_1557 NC_010519.1 1792058 1793485 D KEGG: hso:HS_1072 hypothetical protein; hypothetical protein 1792058..1793485 Haemophilus somnus 2336 6107452 YP_001784878.1 CDS HSM_1558 NC_010519.1 1793562 1794125 D PFAM: protein of unknown function DUF882; peptidase M15A; KEGG: hso:HS_1073 hypothetical protein; hypothetical protein 1793562..1794125 Haemophilus somnus 2336 6107453 YP_001784879.1 CDS HSM_1559 NC_010519.1 1794201 1794833 D PFAM: beta-lactamase; KEGG: hso:HS_1074 glyoxalase II family protein; beta-lactamase domain-containing protein 1794201..1794833 Haemophilus somnus 2336 6107454 YP_001784880.1 CDS HSM_1560 NC_010519.1 1794935 1796224 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1794935..1796224 Haemophilus somnus 2336 6107455 YP_001784881.1 CDS metX NC_010519.1 1796271 1797344 R Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase complement(1796271..1797344) Haemophilus somnus 2336 6107457 YP_001784882.1 CDS HSM_1562 NC_010519.1 1797532 1798227 D PFAM: protein of unknown function DUF218; KEGG: hso:HS_1077 SanA protein; hypothetical protein 1797532..1798227 Haemophilus somnus 2336 6107458 YP_001784883.1 CDS HSM_1563 NC_010519.1 1798957 1799928 D TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: hso:HS_1078 sodium/calcium exchange protein; CaCA family Na(+)/Ca(+) antiporter 1798957..1799928 Haemophilus somnus 2336 6108895 YP_001784884.1 CDS HSM_1564 NC_010519.1 1799949 1800956 R PFAM: high-affinity nickel-transporter; KEGG: hso:HS_1079 permease; high-affinity nickel-transporter complement(1799949..1800956) Haemophilus somnus 2336 6107460 YP_001784885.1 CDS HSM_1565 NC_010519.1 1800947 1801588 R PFAM: protein of unknown function DUF1007; KEGG: hso:HS_1080 hypothetical protein; hypothetical protein complement(1800947..1801588) Haemophilus somnus 2336 6107461 YP_001784886.1 CDS HSM_1566 NC_010519.1 1801820 1802290 D PFAM: protein of unknown function UPF0079; KEGG: hso:HS_1081 ATPase; hypothetical protein 1801820..1802290 Haemophilus somnus 2336 6107462 YP_001784887.1 CDS HSM_1567 NC_010519.1 1802294 1803502 D PFAM: peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: hso:HS_1082 N-acetylmuramoyl-L-alanine amidase; N-acetylmuramoyl-L-alanine amidase 1802294..1803502 Haemophilus somnus 2336 6107463 YP_001784888.1 CDS mutL NC_010519.1 1803518 1805365 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 1803518..1805365 Haemophilus somnus 2336 6107464 YP_001784889.1 CDS miaA NC_010519.1 1805362 1806297 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1805362..1806297 Haemophilus somnus 2336 6107465 YP_001784890.1 CDS HSM_1570 NC_010519.1 1806382 1806894 D KEGG: mmu:673901 hypothetical protein LOC673901; hypothetical protein 1806382..1806894 Haemophilus somnus 2336 6107466 YP_001784891.1 CDS HSM_1571 NC_010519.1 1806992 1818763 D PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_0790 large adhesin; YadA domain-containing protein 1806992..1818763 Haemophilus somnus 2336 6107468 YP_001784892.1 CDS HSM_1572 NC_010519.1 1818885 1820309 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(1818885..1820309) Haemophilus somnus 2336 6107469 YP_001784893.1 CDS HSM_1573 NC_010519.1 1820460 1821626 D TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: hso:HS_1156 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase 1820460..1821626 Haemophilus somnus 2336 6107470 YP_001784894.1 CDS potA NC_010519.1 1821785 1822903 D functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 1821785..1822903 Haemophilus somnus 2336 6107471 YP_001784895.1 CDS potB NC_010519.1 1822887 1823747 D can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1822887..1823747 Haemophilus somnus 2336 6107472 YP_001784896.1 CDS potC NC_010519.1 1823747 1824514 D can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1823747..1824514 Haemophilus somnus 2336 6107473 YP_001784897.1 CDS HSM_1577 NC_010519.1 1824678 1825763 D PFAM: extracellular solute-binding protein family 1; KEGG: hso:HS_1160 spermidine/putrescine-binding periplasmic protein; extracellular solute-binding protein 1824678..1825763 Haemophilus somnus 2336 6107474 YP_001784898.1 CDS HSM_1578 NC_010519.1 1825819 1829253 R TIGRFAM: transcription-repair coupling factor; PFAM: helicase; transcription factor CarD; TRCF domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: hso:HS_1161 transcription-repair coupling factor; transcription-repair coupling factor complement(1825819..1829253) Haemophilus somnus 2336 6107475 YP_001784899.1 CDS HSM_1579 NC_010519.1 1829256 1829972 R Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase complement(1829256..1829972) Haemophilus somnus 2336 6107476 YP_001784900.1 CDS HSM_1580 NC_010519.1 1830112 1832757 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1830112..1832757 Haemophilus somnus 2336 6107477 YP_001784901.1 CDS HSM_1581 NC_010519.1 1832808 1832993 D KEGG: hso:HS_1164 hypothetical protein; hypothetical protein 1832808..1832993 Haemophilus somnus 2336 6107479 YP_001784902.1 CDS HSM_1582 NC_010519.1 1833119 1833445 D TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: hso:HS_1165 alkylphosphonate uptake protein; alkylphosphonate utilization operon protein PhnA 1833119..1833445 Haemophilus somnus 2336 6107480 YP_001784903.1 CDS HSM_1583 NC_010519.1 1833482 1834699 D TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: hso:HS_1166 tyrosine-specific transporter; aromatic amino acid transporter 1833482..1834699 Haemophilus somnus 2336 6107481 YP_001784904.1 CDS HSM_1584 NC_010519.1 1834810 1836084 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(1834810..1836084) Haemophilus somnus 2336 6107482 YP_001784905.1 CDS HSM_1585 NC_010519.1 1836104 1836355 R PFAM: BolA family protein; KEGG: hso:HS_1168 BolA-like protein; BolA family protein complement(1836104..1836355) Haemophilus somnus 2336 6107483 YP_001784906.1 CDS HSM_1586 NC_010519.1 1836368 1836652 R KEGG: hso:HS_1169 conserved hypothetical protein; hypothetical protein complement(1836368..1836652) Haemophilus somnus 2336 6107484 YP_001784907.1 CDS HSM_1587 NC_010519.1 1836704 1837333 R PFAM: toluene tolerance family protein; KEGG: hso:HS_1170 conserved hypothetical protein; toluene tolerance family protein complement(1836704..1837333) Haemophilus somnus 2336 6107485 YP_001784908.1 CDS HSM_1588 NC_010519.1 1837369 1837875 R PFAM: hypothetical protein; KEGG: hso:HS_1171 hypothetical protein; hypothetical protein complement(1837369..1837875) Haemophilus somnus 2336 6107486 YP_001784909.1 CDS HSM_1589 NC_010519.1 1837907 1838692 R PFAM: protein of unknown function DUF140; KEGG: hso:HS_1172 permease, ABC transporter; hypothetical protein complement(1837907..1838692) Haemophilus somnus 2336 6107487 YP_001784910.1 CDS HSM_1590 NC_010519.1 1838689 1839483 R PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1173 ABC transporter ATP-binding protein; ABC transporter complement(1838689..1839483) Haemophilus somnus 2336 6107488 YP_001784911.1 CDS HSM_1591 NC_010519.1 1839703 1840278 D PFAM: protein of unknown function DUF1239; KEGG: hso:HS_1174 hypothetical protein; hypothetical protein 1839703..1840278 Haemophilus somnus 2336 6107490 YP_001784912.1 CDS HSM_1592 NC_010519.1 1840259 1840777 D TIGRFAM: cell envelope biogenesis YhbN; PFAM: OstA family protein; KEGG: hso:HS_1175 hypothetical protein; cell envelope biogenesis YhbN 1840259..1840777 Haemophilus somnus 2336 6107491 YP_001784913.1 CDS HSM_1593 NC_010519.1 1840792 1841517 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_1176 ABC transporter ATP-binding protein; ABC transporter 1840792..1841517 Haemophilus somnus 2336 6107492 YP_001784914.1 CDS HSM_1594 NC_010519.1 1841520 1842080 D PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: hso:HS_1177 nitrogen regulatory IIA protein; PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN 1841520..1842080 Haemophilus somnus 2336 6107493 YP_001784915.1 CDS HSM_1595 NC_010519.1 1842083 1842943 D PFAM: uncharacterised P-loop ATPase protein UPF0042; KEGG: hso:HS_1178 hypothetical protein; hypothetical protein 1842083..1842943 Haemophilus somnus 2336 6107494 YP_001784916.1 CDS metG NC_010519.1 1842979 1845030 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1842979..1845030) Haemophilus somnus 2336 6107495 YP_001784917.1 CDS HSM_1597 NC_010519.1 1845171 1846292 D KEGG: hso:HS_1180 ATP-binding protein, MRP protein; ATPase 1845171..1846292 Haemophilus somnus 2336 6107496 YP_001784918.1 CDS HSM_1598 NC_010519.1 1846733 1847038 R TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: hit:NTHI0839 hypothetical protein; addiction module antitoxin complement(1846733..1847038) Haemophilus somnus 2336 6107497 YP_001784919.1 CDS HSM_1599 NC_010519.1 1847042 1847332 R TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; KEGG: hit:NTHI0838 DNA-damage-inducible protein J, negative regulator of translation; addiction module antitoxin complement(1847042..1847332) Haemophilus somnus 2336 6107498 YP_001784920.1 CDS HSM_1600 NC_010519.1 1847504 1848052 R KEGG: hso:HS_0574 oxidoreductase component; oxidoreductase component complement(1847504..1848052) Haemophilus somnus 2336 6107499 YP_001784921.1 CDS HSM_1601 NC_010519.1 1848064 1848684 R PFAM: NAD(P)H dehydrogenase (quinone); KEGG: hso:HS_0573 NAD(P)H2 dehydrogenase, quinone family; NAD(P)H dehydrogenase (quinone) complement(1848064..1848684) Haemophilus somnus 2336 6107502 YP_001784922.1 CDS HSM_1602 NC_010519.1 1848694 1849137 R PFAM: protein of unknown function DUF107; KEGG: hso:HS_0572 regulator of membrane protease activity; hypothetical protein complement(1848694..1849137) Haemophilus somnus 2336 6107503 YP_001784923.1 CDS HSM_1603 NC_010519.1 1849184 1850104 R PFAM: hypothetical protein; KEGG: hso:HS_0571 membrane protease band 7 family; hypothetical protein complement(1849184..1850104) Haemophilus somnus 2336 6107504 YP_001784924.1 CDS HSM_1604 NC_010519.1 1850387 1850839 D catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 1850387..1850839 Haemophilus somnus 2336 6107505 YP_001784925.1 CDS HSM_1605 NC_010519.1 1851028 1851489 D TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: hso:HS_0569 acetyl-CoA carboxylase; acetyl-CoA carboxylase, biotin carboxyl carrier protein 1851028..1851489 Haemophilus somnus 2336 6107506 YP_001784926.1 CDS HSM_1606 NC_010519.1 1851550 1852896 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 1851550..1852896 Haemophilus somnus 2336 6107507 YP_001784927.1 CDS panF NC_010519.1 1853201 1854643 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 1853201..1854643 Haemophilus somnus 2336 6107508 YP_001784928.1 CDS prmA NC_010519.1 1854644 1855534 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 1854644..1855534 Haemophilus somnus 2336 6107509 YP_001784929.1 CDS HSM_1609 NC_010519.1 1855721 1856704 D TIGRFAM: hypothetical protein; PFAM: dihydrouridine synthase; dihydroorotate dehydrogenase; KEGG: hso:HS_0565 tRNA-dihydrouridine synthase B; nifR3 family TIM-barrel protein 1855721..1856704 Haemophilus somnus 2336 6107510 YP_001784930.1 CDS fis NC_010519.1 1856698 1856994 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 1856698..1856994 Haemophilus somnus 2336 6107511 YP_001784931.1 CDS HSM_1611 NC_010519.1 1857043 1858041 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(1857043..1858041) Haemophilus somnus 2336 6107513 YP_001784932.1 CDS HSM_1612 NC_010519.1 1858255 1859112 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(1858255..1859112) Haemophilus somnus 2336 6107514 YP_001784933.1 CDS eno NC_010519.1 1859399 1860700 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(1859399..1860700) Haemophilus somnus 2336 6107515 YP_001784934.1 CDS HSM_1614 NC_010519.1 1860940 1861518 D KEGG: hso:HS_0560 type I restriction enzyme, specificity subunit; type I restriction enzyme, specificity subunit 1860940..1861518 Haemophilus somnus 2336 6107516 YP_001784935.1 CDS HSM_1615 NC_010519.1 1861511 1864711 D TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases; KEGG: hso:HS_0559 type I site-specific deoxyribonuclease, restriction subunit; HsdR family type I site-specific deoxyribonuclease 1861511..1864711 Haemophilus somnus 2336 6107517 YP_001784936.1 CDS HSM_1616 NC_010519.1 1864717 1865697 D PFAM: Abi family protein; KEGG: noc:Noc_1806 abortive infection bacteriophage resistance protein; Abi family protein 1864717..1865697 Haemophilus somnus 2336 6107518 YP_001784937.1 CDS HSM_1617 NC_010519.1 1865787 1867019 D PFAM: restriction modification system DNA specificity domain; KEGG: hso:HS_0556 type I restriction enzyme, specificity subunit; restriction modification system DNA specificity subunit 1865787..1867019 Haemophilus somnus 2336 6107519 YP_001784938.1 CDS HSM_1618 NC_010519.1 1867032 1867592 D PFAM: filamentation induced by cAMP protein Fic; KEGG: hin:HI0977 cell filamentation protein; filamentation induced by cAMP protein fic 1867032..1867592 Haemophilus somnus 2336 6107520 YP_001784939.1 CDS HSM_1619 NC_010519.1 1867646 1869259 D TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: llc:LACR_1215 type I restriction-modification system methyltransferase subunit; type I restriction-modification system, M subunit 1867646..1869259 Haemophilus somnus 2336 6107521 YP_001784940.1 CDS HSM_1620 NC_010519.1 1869566 1869862 D KEGG: mfa:Mfla_1216 restriction modification system DNA specificity domain; restriction modification system DNA specificity subunit 1869566..1869862 Haemophilus somnus 2336 6107522 YP_001784941.1 CDS HSM_1621 NC_010519.1 1869884 1870810 D PFAM: phage integrase family protein; KEGG: hso:HS_0555 phage integrase; phage integrase family protein 1869884..1870810 Haemophilus somnus 2336 6107524 YP_001784942.1 CDS HSM_1622 NC_010519.1 1870823 1871338 R KEGG: yps:YPTB0536 type I restriction enzyme, S subunit; type I restriction enzyme, S subunit complement(1870823..1871338) Haemophilus somnus 2336 6107525 YP_001784943.1 CDS HSM_1623 NC_010519.1 1871444 1871668 R hypothetical protein complement(1871444..1871668) Haemophilus somnus 2336 6107526 YP_001784944.1 CDS HSM_1624 NC_010519.1 1871683 1872711 D PFAM: acyltransferase 3; KEGG: hso:HS_0553 acetyltransferase; acyltransferase 3 1871683..1872711 Haemophilus somnus 2336 6107527 YP_001784945.1 CDS HSM_1625 NC_010519.1 1872727 1873143 R PFAM: transposase IS200-family protein; KEGG: hso:HS_1391 transposase; transposase IS200-family protein complement(1872727..1873143) Haemophilus somnus 2336 6107528 YP_001784946.1 CDS HSM_1626 NC_010519.1 1873190 1874326 D TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: hso:HS_0583 transposase; IS605 family transposase OrfB 1873190..1874326 Haemophilus somnus 2336 6107529 YP_001784947.1 CDS HSM_1627 NC_010519.1 1874609 1874896 D KEGG: hso:HS_0525 hypothetical protein; hypothetical protein 1874609..1874896 Haemophilus somnus 2336 6107530 YP_001784948.1 CDS HSM_1628 NC_010519.1 1875023 1875286 D KEGG: hso:HS_0527 hypothetical protein; hypothetical protein 1875023..1875286 Haemophilus somnus 2336 6107531 YP_001784949.1 CDS HSM_1629 NC_010519.1 1875423 1875914 D KEGG: hso:HS_0528 hypothetical protein; hypothetical protein 1875423..1875914 Haemophilus somnus 2336 6107532 YP_001784950.1 CDS HSM_1630 NC_010519.1 1875907 1876092 D hypothetical protein 1875907..1876092 Haemophilus somnus 2336 6107533 YP_001784951.1 CDS HSM_1631 NC_010519.1 1876215 1877351 R TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: hso:HS_0583 transposase; IS605 family transposase OrfB complement(1876215..1877351) Haemophilus somnus 2336 6107535 YP_001784952.1 CDS HSM_1632 NC_010519.1 1877398 1877814 D PFAM: transposase IS200-family protein; KEGG: hso:HS_1391 transposase; transposase IS200-family protein 1877398..1877814 Haemophilus somnus 2336 6107536 YP_001784953.1 CDS HSM_1633 NC_010519.1 1877974 1878402 R hypothetical protein complement(1877974..1878402) Haemophilus somnus 2336 6107537 YP_001784954.1 CDS HSM_1634 NC_010519.1 1879063 1879773 R KEGG: plu:plu0225 hypothetical protein; hypothetical protein complement(1879063..1879773) Haemophilus somnus 2336 6107538 YP_001784955.1 CDS HSM_1635 NC_010519.1 1879770 1880156 R KEGG: ngo:NGO1591 hypothetical protein; hypothetical protein complement(1879770..1880156) Haemophilus somnus 2336 6107539 YP_001784956.1 CDS HSM_1636 NC_010519.1 1880159 1880308 R KEGG: nme:NMB0372 hypothetical protein; hypothetical protein complement(1880159..1880308) Haemophilus somnus 2336 6107540 YP_001784957.1 CDS HSM_1637 NC_010519.1 1880376 1880621 R hypothetical protein complement(1880376..1880621) Haemophilus somnus 2336 6107541 YP_001784958.1 CDS HSM_1638 NC_010519.1 1880626 1882686 R KEGG: msu:MS1164 hypothetical protein; hypothetical protein complement(1880626..1882686) Haemophilus somnus 2336 6107542 YP_001784959.1 CDS HSM_1639 NC_010519.1 1883603 1884052 R hypothetical protein complement(1883603..1884052) Haemophilus somnus 2336 6107543 YP_001784960.1 CDS HSM_1640 NC_010519.1 1884363 1884803 R KEGG: plu:plu1354 hypothetical protein; hypothetical protein complement(1884363..1884803) Haemophilus somnus 2336 6107544 YP_001784961.1 CDS HSM_1641 NC_010519.1 1884812 1886914 R KEGG: msu:MS1167 FhaB protein; hypothetical protein complement(1884812..1886914) Haemophilus somnus 2336 6107546 YP_001784962.1 CDS HSM_1642 NC_010519.1 1887064 1887519 R hypothetical protein complement(1887064..1887519) Haemophilus somnus 2336 6107547 YP_001784963.1 CDS HSM_1643 NC_010519.1 1887521 1887772 R KEGG: bld:BLi01315 YeeF; hypothetical protein complement(1887521..1887772) Haemophilus somnus 2336 6107548 YP_001784964.1 CDS HSM_1644 NC_010519.1 1888067 1888423 R hypothetical protein complement(1888067..1888423) Haemophilus somnus 2336 6107549 YP_001784965.1 CDS HSM_1645 NC_010519.1 1888675 1888926 R hypothetical protein complement(1888675..1888926) Haemophilus somnus 2336 6107550 YP_001784966.1 CDS HSM_1646 NC_010519.1 1888923 1890218 R PFAM: Cytotoxic domain protein; KEGG: cvi:CV2871 probable hemagglutinin; cytotoxic domain-containing protein complement(1888923..1890218) Haemophilus somnus 2336 6107551 YP_001784967.1 CDS HSM_1647 NC_010519.1 1890444 1892567 R KEGG: msu:MS1163 FhaB protein; FhaB protein complement(1890444..1892567) Haemophilus somnus 2336 6107552 YP_001784968.1 CDS HSM_1648 NC_010519.1 1892583 1892975 R hypothetical protein complement(1892583..1892975) Haemophilus somnus 2336 6107553 YP_001784969.1 CDS HSM_1649 NC_010519.1 1892975 1893256 R hypothetical protein complement(1892975..1893256) Haemophilus somnus 2336 6107554 YP_001784970.1 CDS HSM_1650 NC_010519.1 1893295 1893780 R hypothetical protein complement(1893295..1893780) Haemophilus somnus 2336 6107555 YP_001784971.1 CDS HSM_1651 NC_010519.1 1893785 1902019 R TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: msu:MS1167 FhaB protein; filamentous hemagglutinin outer membrane protein complement(1893785..1902019) Haemophilus somnus 2336 6107557 YP_001784972.1 CDS HSM_1652 NC_010519.1 1901988 1902182 R KEGG: msu:MS1169 FhaC protein; hypothetical protein complement(1901988..1902182) Haemophilus somnus 2336 6107558 YP_001784973.1 CDS HSM_1653 NC_010519.1 1902170 1902466 R hypothetical protein complement(1902170..1902466) Haemophilus somnus 2336 6107559 YP_001784974.1 CDS HSM_1654 NC_010519.1 1902931 1903641 R TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: hso:HS_0541 conserved hypothetical protein; hypothetical protein complement(1902931..1903641) Haemophilus somnus 2336 6107560 YP_001784975.1 CDS HSM_1655 NC_010519.1 1903824 1904609 D TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; methyltransferase type 11; methyltransferase type 12; KEGG: hso:HS_0542 ubiquinone/menaquinone biosynthesis methyltransferase; ubiquinone/menaquinone biosynthesis methyltransferase 1903824..1904609 Haemophilus somnus 2336 6107561 YP_001784976.1 CDS HSM_1656 NC_010519.1 1904618 1905253 D PFAM: protein of unknown function DUF1243; KEGG: hso:HS_0543 conserved hypothetical protein; hypothetical protein 1904618..1905253 Haemophilus somnus 2336 6107562 YP_001784977.1 CDS HSM_1657 NC_010519.1 1905250 1906887 D TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: hso:HS_0544 ubiquinone biosynthesis protein; 2-polyprenylphenol 6-hydroxylase 1905250..1906887 Haemophilus somnus 2336 6107563 YP_001784978.1 CDS HSM_1658 NC_010519.1 1906992 1907213 D TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: hso:HS_0545 sec-independent protein translocase protein, TatA/E family; twin arginine-targeting protein translocase 1906992..1907213 Haemophilus somnus 2336 6107564 YP_001784979.1 CDS HSM_1659 NC_010519.1 1907217 1907771 D TIGRFAM: twin-arginine translocation protein, TatB subunit; KEGG: hso:HS_0546 sec-independent protein translocase protein; twin-arginine translocation protein subunit TatB 1907217..1907771 Haemophilus somnus 2336 6107565 YP_001784980.1 CDS HSM_1660 NC_010519.1 1907768 1908505 D TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: hso:HS_0547 sec-independent protein translocase protein; Sec-independent protein translocase subunit TatC 1907768..1908505 Haemophilus somnus 2336 6107566 YP_001784981.1 CDS HSM_1661 NC_010519.1 1908571 1909593 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 1908571..1909593 Haemophilus somnus 2336 6107568 YP_001784982.1 CDS purT NC_010519.1 1909650 1910894 R non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 complement(1909650..1910894) Haemophilus somnus 2336 6107569 YP_001784983.1 CDS HSM_1663 NC_010519.1 1910872 1911378 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(1910872..1911378) Haemophilus somnus 2336 6107570 YP_001784984.1 CDS HSM_1664 NC_010519.1 1911659 1913665 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1911659..1913665 Haemophilus somnus 2336 6107571 YP_001784985.1 CDS HSM_1665 NC_010519.1 1913858 1914580 R KEGG: net:Neut_2561 type III restriction enzyme, res subunit; type III restriction enzyme, res subunit complement(1913858..1914580) Haemophilus somnus 2336 6107572 YP_001784986.1 CDS HSM_1666 NC_010519.1 1914598 1918695 R PFAM: helicase; type III restriction protein res subunit; SMART: DEAD-like helicases; KEGG: net:Neut_2561 type III restriction enzyme, res subunit; type III restriction protein res subunit complement(1914598..1918695) Haemophilus somnus 2336 6107573 YP_001784987.1 CDS HSM_1667 NC_010519.1 1919115 1919243 R KEGG: hso:HS_0638 Lob1 protein; Lob1 protein complement(1919115..1919243) Haemophilus somnus 2336 6107574 YP_001784988.1 CDS pyrG NC_010519.1 1919528 1921156 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1919528..1921156 Haemophilus somnus 2336 6107575 YP_001784989.1 CDS HSM_1669 NC_010519.1 1921204 1922079 R KEGG: hso:HS_0553 acetyltransferase; acetyltransferase complement(1921204..1922079) Haemophilus somnus 2336 6107576 YP_001784990.1 CDS HSM_1670 NC_010519.1 1922216 1923352 R TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: hso:HS_0583 transposase; IS605 family transposase OrfB complement(1922216..1923352) Haemophilus somnus 2336 6107577 YP_001784991.1 CDS HSM_1671 NC_010519.1 1923399 1923815 D PFAM: transposase IS200-family protein; KEGG: hso:HS_1391 transposase; transposase IS200-family protein 1923399..1923815 Haemophilus somnus 2336 6107579 YP_001784992.1 CDS HSM_1672 NC_010519.1 1923959 1924198 R KEGG: hso:HS_0524 hypothetical protein; hypothetical protein complement(1923959..1924198) Haemophilus somnus 2336 6107580 YP_001784993.1 CDS HSM_1673 NC_010519.1 1924199 1924444 R KEGG: hso:HS_0523 hypothetical protein; hypothetical protein complement(1924199..1924444) Haemophilus somnus 2336 6107581 YP_001784994.1 CDS HSM_1674 NC_010519.1 1924454 1924675 R PFAM: prophage CP4-57 regulator; KEGG: hso:HS_0522 phage transcriptional regulator; phage transcriptional regulator AlpA complement(1924454..1924675) Haemophilus somnus 2336 6107582 YP_001784995.1 CDS HSM_1675 NC_010519.1 1924840 1925814 R hypothetical protein complement(1924840..1925814) Haemophilus somnus 2336 6107583 YP_001784996.1 CDS HSM_1676 NC_010519.1 1926347 1927594 R PFAM: phage integrase family protein; KEGG: hso:HS_0519 phage integrase; phage integrase family protein complement(1926347..1927594) Haemophilus somnus 2336 6107584 YP_001784997.1 CDS HSM_1677 NC_010519.1 1928343 1928921 D KEGG: efa:EF3160 hypothetical protein; hypothetical protein 1928343..1928921 Haemophilus somnus 2336 6107585 YP_001784998.1 CDS HSM_1678 NC_010519.1 1929653 1930090 R KEGG: plu:plu4544 hypothetical protein; hypothetical protein complement(1929653..1930090) Haemophilus somnus 2336 6107586 YP_001784999.1 CDS HSM_1679 NC_010519.1 1930240 1931139 D PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: hso:HS_0001 integrase; phage integrase family protein 1930240..1931139 Haemophilus somnus 2336 6107587 YP_001785000.1 CDS HSM_1680 NC_010519.1 1931538 1932512 D PFAM: Integrase catalytic region; KEGG: ssp:SSP1423 transposase; integrase catalytic region 1931538..1932512 Haemophilus somnus 2336 6107588 YP_001785001.1 CDS HSM_1681 NC_010519.1 1932585 1933382 R KEGG: hit:NTHI0153 type I restriction enzyme M subunit; type I restriction enzyme M subunit complement(1932585..1933382) Haemophilus somnus 2336 6107590 YP_001785002.1 CDS HSM_1682 NC_010519.1 1933455 1934201 R KEGG: hdu:HD0915 hypothetical protein; hypothetical protein complement(1933455..1934201) Haemophilus somnus 2336 6107591 YP_001785003.1 CDS HSM_1683 NC_010519.1 1934341 1935315 R PFAM: domain of unknown function DUF1738; KEGG: hso:HS_1780 antirestriction protein; hypothetical protein complement(1934341..1935315) Haemophilus somnus 2336 6107592 YP_001785004.1 CDS HSM_1684 NC_010519.1 1935560 1935967 R KEGG: hso:HS_1781 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(1935560..1935967) Haemophilus somnus 2336 6107593 YP_001785005.1 CDS HSM_1685 NC_010519.1 1936083 1936925 R hypothetical protein complement(1936083..1936925) Haemophilus somnus 2336 6107594 YP_001785006.1 CDS HSM_1686 NC_010519.1 1937003 1937398 R hypothetical protein complement(1937003..1937398) Haemophilus somnus 2336 6107595 YP_001785007.1 CDS HSM_1687 NC_010519.1 1937497 1937742 R KEGG: hso:HS_1778 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(1937497..1937742) Haemophilus somnus 2336 6107596 YP_001785008.1 CDS HSM_1688 NC_010519.1 1937814 1938167 R KEGG: hit:NTHI0148 hypothetical protein; hypothetical protein complement(1937814..1938167) Haemophilus somnus 2336 6107597 YP_001785009.1 CDS HSM_1689 NC_010519.1 1938541 1938984 D PFAM: protein of unknown function DUF1525; KEGG: hso:HS_1776 hypothetical protein; hypothetical protein 1938541..1938984 Haemophilus somnus 2336 6107598 YP_001785010.1 CDS HSM_1690 NC_010519.1 1938981 1939922 D PFAM: protein of unknown function DUF1527; KEGG: hso:HS_1775 hypothetical protein; hypothetical protein 1938981..1939922 Haemophilus somnus 2336 6107599 YP_001785011.1 CDS HSM_1691 NC_010519.1 1939940 1941952 D KEGG: hso:HS_1774 hypothetical protein; hypothetical protein 1939940..1941952 Haemophilus somnus 2336 6107601 YP_001785012.1 CDS HSM_1692 NC_010519.1 1941973 1942401 D KEGG: hit:NTHI0144 hypothetical protein; hypothetical protein 1941973..1942401 Haemophilus somnus 2336 6107602 YP_001785013.1 CDS HSM_1693 NC_010519.1 1942617 1943087 D KEGG: spa:M6_Spy0066 unknown phage protein; phage protein 1942617..1943087 Haemophilus somnus 2336 6107603 YP_001785014.1 CDS HSM_1694 NC_010519.1 1943108 1943449 D hypothetical protein 1943108..1943449 Haemophilus somnus 2336 6107604 YP_001785015.1 CDS HSM_1695 NC_010519.1 1943495 1944967 R KEGG: hit:NTHI0137 conserved membrane protein; hypothetical protein complement(1943495..1944967) Haemophilus somnus 2336 6107605 YP_001785016.1 CDS HSM_1696 NC_010519.1 1944978 1945295 R KEGG: hso:HS_1766 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(1944978..1945295) Haemophilus somnus 2336 6107606 YP_001785017.1 CDS HSM_1697 NC_010519.1 1945285 1945713 R KEGG: hdu:HD0931 hypothetical protein; hypothetical protein complement(1945285..1945713) Haemophilus somnus 2336 6107607 YP_001785018.1 CDS HSM_1698 NC_010519.1 1945713 1948550 R KEGG: hso:HS_1764 hypothetical protein; hypothetical protein complement(1945713..1948550) Haemophilus somnus 2336 6107608 YP_001785019.1 CDS HSM_1699 NC_010519.1 1948553 1948951 R KEGG: hso:HS_1763 hypothetical protein; hypothetical protein complement(1948553..1948951) Haemophilus somnus 2336 6107609 YP_001785020.1 CDS HSM_1700 NC_010519.1 1948964 1950418 R KEGG: hdu:HD0935 hypothetical protein; hypothetical protein complement(1948964..1950418) Haemophilus somnus 2336 6107610 YP_001785021.1 CDS HSM_1701 NC_010519.1 1950430 1951314 R KEGG: hit:NTHI0131 hypothetical protein; hypothetical protein complement(1950430..1951314) Haemophilus somnus 2336 6107613 YP_001785022.1 CDS HSM_1702 NC_010519.1 1951314 1951958 R KEGG: hso:HS_1760 hypothetical protein; hypothetical protein complement(1951314..1951958) Haemophilus somnus 2336 6107614 YP_001785023.1 CDS HSM_1703 NC_010519.1 1951962 1952327 R KEGG: hso:HS_1759 hypothetical protein; hypothetical protein complement(1951962..1952327) Haemophilus somnus 2336 6107615 YP_001785024.1 CDS HSM_1704 NC_010519.1 1952350 1952739 R KEGG: hso:HS_1758 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(1952350..1952739) Haemophilus somnus 2336 6107616 YP_001785025.1 CDS HSM_1705 NC_010519.1 1952754 1952990 R KEGG: hso:HS_1757 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(1952754..1952990) Haemophilus somnus 2336 6107617 YP_001785026.1 CDS HSM_1706 NC_010519.1 1952987 1953313 R KEGG: hso:HS_1756 hypothetical protein; hypothetical protein complement(1952987..1953313) Haemophilus somnus 2336 6107618 YP_001785027.1 CDS HSM_1707 NC_010519.1 1953500 1953883 D KEGG: hso:HS_1789 Haemophilus-specific protein, uncharacterized; hypothetical protein 1953500..1953883 Haemophilus somnus 2336 6107619 YP_001785028.1 CDS HSM_1708 NC_010519.1 1953915 1954610 R KEGG: hit:NTHI0126 conserved membrane protein; hypothetical protein complement(1953915..1954610) Haemophilus somnus 2336 6107620 YP_001785029.1 CDS HSM_1709 NC_010519.1 1954607 1954960 R KEGG: hso:HS_1752 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(1954607..1954960) Haemophilus somnus 2336 6107621 YP_001785030.1 CDS HSM_1710 NC_010519.1 1954953 1957154 R KEGG: hso:HS_1751 hypothetical protein; hypothetical protein complement(1954953..1957154) Haemophilus somnus 2336 6107622 YP_001785031.1 CDS HSM_1711 NC_010519.1 1957154 1957660 R KEGG: hso:HS_1750 hypothetical protein; hypothetical protein complement(1957154..1957660) Haemophilus somnus 2336 6107624 YP_001785032.1 CDS HSM_1712 NC_010519.1 1957663 1958433 R KEGG: hit:NTHI0122 conserved exported protein; hypothetical protein complement(1957663..1958433) Haemophilus somnus 2336 6107625 YP_001785033.1 CDS HSM_1713 NC_010519.1 1958412 1959185 R KEGG: hso:HS_1747 hypothetical protein; hypothetical protein complement(1958412..1959185) Haemophilus somnus 2336 6107626 YP_001785034.1 CDS HSM_1714 NC_010519.1 1959185 1959814 R KEGG: hit:NTHI0120 conserved lipoprotein; lipoprotein complement(1959185..1959814) Haemophilus somnus 2336 6107627 YP_001785035.1 CDS HSM_1715 NC_010519.1 1959973 1960233 R KEGG: pau:PA14_59530 hypothetical protein; hypothetical protein complement(1959973..1960233) Haemophilus somnus 2336 6107628 YP_001785036.1 CDS HSM_1716 NC_010519.1 1960346 1960708 R KEGG: hso:HS_1744 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(1960346..1960708) Haemophilus somnus 2336 6107629 YP_001785037.1 CDS HSM_1717 NC_010519.1 1960788 1961195 R KEGG: hso:HS_1739 hypothetical protein; hypothetical protein complement(1960788..1961195) Haemophilus somnus 2336 6107630 YP_001785038.1 CDS HSM_1718 NC_010519.1 1961221 1961901 R hypothetical protein complement(1961221..1961901) Haemophilus somnus 2336 6107631 YP_001785039.1 CDS HSM_1719 NC_010519.1 1962007 1962438 R KEGG: hso:HS_1738 hypothetical protein; hypothetical protein complement(1962007..1962438) Haemophilus somnus 2336 6107632 YP_001785040.1 CDS HSM_1720 NC_010519.1 1963256 1965307 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(1963256..1965307) Haemophilus somnus 2336 6107633 YP_001785041.1 CDS HSM_1721 NC_010519.1 1965467 1965985 R KEGG: hso:HS_1732 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(1965467..1965985) Haemophilus somnus 2336 6107635 YP_001785042.1 CDS HSM_1722 NC_010519.1 1966462 1967172 D KEGG: hso:HS_1735 Haemophilus-specific protein, uncharacterized; hypothetical protein 1966462..1967172 Haemophilus somnus 2336 6107636 YP_001785043.1 CDS HSM_1723 NC_010519.1 1967711 1968478 R PFAM: aldo/keto reductase; KEGG: ade:Adeh_3215 aldo/keto reductase; aldo/keto reductase complement(1967711..1968478) Haemophilus somnus 2336 6107637 YP_001785044.1 CDS HSM_1724 NC_010519.1 1968477 1968797 D hypothetical protein 1968477..1968797 Haemophilus somnus 2336 6107638 YP_001785045.1 CDS HSM_1725 NC_010519.1 1968979 1969434 D PFAM: protein of unknown function DUF411; KEGG: pmu:PM1939 hypothetical S.typhimurium; hypothetical protein 1968979..1969434 Haemophilus somnus 2336 6107639 YP_001785046.1 CDS HSM_1726 NC_010519.1 1969449 1970996 D PFAM: multicopper oxidase type 1; multicopper oxidase type 2; multicopper oxidase type 3; KEGG: pmu:PM1938 hypothetical E.coli; multicopper oxidase type 3 1969449..1970996 Haemophilus somnus 2336 6107640 YP_001785047.1 CDS HSM_1727 NC_010519.1 1971086 1971241 R KEGG: bam:Bamb_5387 alcohol dehydrogenase, zinc-binding domain protein; alcohol dehydrogenase complement(1971086..1971241) Haemophilus somnus 2336 6107641 YP_001785048.1 CDS HSM_1728 NC_010519.1 1971664 1972068 D TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; KEGG: hit:NTHI0403 probable heavy metal dependent transcriptional regulator; MerR family transcriptional regulator 1971664..1972068 Haemophilus somnus 2336 6107642 YP_001785049.1 CDS HSM_1729 NC_010519.1 1972283 1972600 R PFAM: protein of unknown function DUF411; KEGG: pmu:PM1939 hypothetical S.typhimurium; hypothetical protein complement(1972283..1972600) Haemophilus somnus 2336 6107643 YP_001785050.1 CDS HSM_1730 NC_010519.1 1972853 1974457 R PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: pmu:PM1938 hypothetical E.coli; multicopper oxidase type 3 complement(1972853..1974457) Haemophilus somnus 2336 6107644 YP_001785051.1 CDS HSM_1731 NC_010519.1 1974826 1977018 R TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: haloacid dehalogenase; E1-E2 ATPase-associated domain protein; KEGG: neu:NE1216 haloacid dehalogenase/epoxide hydrolase family:E1-E2 ATPase; ATPase P complement(1974826..1977018) Haemophilus somnus 2336 6107646 YP_001785052.1 CDS HSM_1732 NC_010519.1 1977326 1978072 R PFAM: protein of unknown function DUF305; KEGG: par:Psyc_0285 hypothetical protein; hypothetical protein complement(1977326..1978072) Haemophilus somnus 2336 6107647 YP_001785053.1 CDS HSM_1733 NC_010519.1 1978360 1978878 D KEGG: ret:RHE_PF00025 hypothetical protein; hypothetical protein 1978360..1978878 Haemophilus somnus 2336 6107648 YP_001785054.1 CDS HSM_1734 NC_010519.1 1978881 1979504 R PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: sty:HCM1.243 tetracycline repressor protein; TetR family transcriptional regulator complement(1978881..1979504) Haemophilus somnus 2336 6107649 YP_001785055.1 CDS HSM_1735 NC_010519.1 1979596 1980798 D PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: sty:HCM1.241c tetracycline resistance protein; major facilitator transporter 1979596..1980798 Haemophilus somnus 2336 6107650 YP_001785056.1 CDS HSM_1736 NC_010519.1 1980899 1981231 R PFAM: small multidrug resistance protein; KEGG: nme:NMB0393 multidrug resistance protein; small multidrug resistance protein complement(1980899..1981231) Haemophilus somnus 2336 6107651 YP_001785057.1 CDS HSM_1737 NC_010519.1 1981270 1981719 R PFAM: regulatory protein MarR; KEGG: msu:MS2146 MarR protein; MarR family transcriptional regulator complement(1981270..1981719) Haemophilus somnus 2336 6107652 YP_001785058.1 CDS HSM_1738 NC_010519.1 1981742 1982113 R PFAM: protein of unknown function DUF1304; KEGG: nmc:NMC0467 hypothetical protein; hypothetical protein complement(1981742..1982113) Haemophilus somnus 2336 6107653 YP_001785059.1 CDS HSM_1739 NC_010519.1 1982332 1983432 R KEGG: msu:MS2120 hypothetical protein; hypothetical protein complement(1982332..1983432) Haemophilus somnus 2336 6107654 YP_001785060.1 CDS HSM_1740 NC_010519.1 1983604 1984218 R PFAM: cation efflux protein; KEGG: pmu:PM1942 unknown; cation efflux protein complement(1983604..1984218) Haemophilus somnus 2336 6107655 YP_001785061.1 CDS HSM_1741 NC_010519.1 1984290 1984688 D PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; KEGG: pmu:PM1941 transcriptional regulator, merR family; MerR family transcriptional regulator 1984290..1984688 Haemophilus somnus 2336 6107657 YP_001785062.1 CDS HSM_1742 NC_010519.1 1984727 1984873 D KEGG: pmu:PM1943 hypothetical Synechocystis sp.; hypothetical protein 1984727..1984873 Haemophilus somnus 2336 6107658 YP_001785063.1 CDS HSM_1743 NC_010519.1 1984910 1985062 D KEGG: pmu:PM1943 hypothetical Synechocystis sp.; hypothetical protein 1984910..1985062 Haemophilus somnus 2336 6107659 YP_001785064.1 CDS HSM_1744 NC_010519.1 1985115 1985723 R PFAM: alcohol dehydrogenase zinc-binding domain protein; KEGG: pmu:PM1940 quinone reductase homolog; alcohol dehydrogenase complement(1985115..1985723) Haemophilus somnus 2336 6107660 YP_001785065.1 CDS HSM_1745 NC_010519.1 1986316 1986768 R TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: hso:HS_1729 single-stranded DNA binding protein; single-strand binding protein complement(1986316..1986768) Haemophilus somnus 2336 6107661 YP_001785066.1 CDS HSM_1746 NC_010519.1 1987102 1987587 R KEGG: hit:NTHI0108 hypothetical protein; hypothetical protein complement(1987102..1987587) Haemophilus somnus 2336 6107662 YP_001785067.1 CDS HSM_1747 NC_010519.1 1987596 1988354 R KEGG: hit:NTHI0107 hypothetical protein; hypothetical protein complement(1987596..1988354) Haemophilus somnus 2336 6107663 YP_001785068.1 CDS HSM_1748 NC_010519.1 1988533 1989723 R KEGG: hit:NTHI0106 hypothetical protein; hypothetical protein complement(1988533..1989723) Haemophilus somnus 2336 6107664 YP_001785069.1 CDS HSM_1749 NC_010519.1 1989882 1990439 R KEGG: hdu:HD0969 hypothetical protein; hypothetical protein complement(1989882..1990439) Haemophilus somnus 2336 6107665 YP_001785070.1 CDS HSM_1750 NC_010519.1 1990432 1992078 R KEGG: hit:NTHI0103 hypothetical protein; hypothetical protein complement(1990432..1992078) Haemophilus somnus 2336 6107666 YP_001785071.1 CDS HSM_1751 NC_010519.1 1992087 1993448 R TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase; SMART: ATPase AAA; KEGG: hit:NTHI0102 replicative DNA helicase; replicative DNA helicase complement(1992087..1993448) Haemophilus somnus 2336 6107668 YP_001785072.1 CDS HSM_1752 NC_010519.1 1993460 1994284 R KEGG: hit:NTHI0101 predicted ATPase involved in chromosome partitioning; chromosome partitioning ATPase complement(1993460..1994284) Haemophilus somnus 2336 6107669 YP_001785073.1 CDS HSM_1753 NC_010519.1 1994707 1995777 R PFAM: permease YjgP/YjgQ family protein; KEGG: hso:HS_0518 conserved permease; YjgP/YjgQ family permease complement(1994707..1995777) Haemophilus somnus 2336 6108896 YP_001785074.1 CDS HSM_1754 NC_010519.1 1995790 1996893 R PFAM: permease YjgP/YjgQ family protein; KEGG: hso:HS_0517 conserved permease; YjgP/YjgQ family permease complement(1995790..1996893) Haemophilus somnus 2336 6107671 YP_001785075.1 CDS HSM_1755 NC_010519.1 1997012 1998499 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 1997012..1998499 Haemophilus somnus 2336 6107672 YP_001785076.1 CDS HSM_1756 NC_010519.1 1998772 1999530 D PFAM: regulatory protein GntR HTH; regulatory protein DeoR; hypothetical protein; regulatory protein DeoR; KEGG: hso:HS_0515 glycerol-3-phosphate regulon repressor (glp operon repressor); DeoR family transcriptional regulator 1998772..1999530 Haemophilus somnus 2336 6107673 YP_001785077.1 CDS glpC NC_010519.1 1999580 2000851 R anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C complement(1999580..2000851) Haemophilus somnus 2336 6107674 YP_001785078.1 CDS HSM_1758 NC_010519.1 2000862 2002166 R sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B complement(2000862..2002166) Haemophilus somnus 2336 6107675 YP_001785079.1 CDS glpA NC_010519.1 2002150 2003838 R anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A complement(2002150..2003838) Haemophilus somnus 2336 6107676 YP_001785080.1 CDS HSM_1760 NC_010519.1 2004164 2005609 D TIGRFAM: phosphoglycerate transporter; glycerol-3-phosphate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_0511 glycerol 3-phosphate transporter; glycerol-3-phosphate transporter 2004164..2005609 Haemophilus somnus 2336 6107677 YP_001785081.1 CDS glpQ NC_010519.1 2005723 2006808 D hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 2005723..2006808 Haemophilus somnus 2336 6107679 YP_001785082.1 CDS ruvC NC_010519.1 2006888 2007487 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(2006888..2007487) Haemophilus somnus 2336 6107680 YP_001785083.1 CDS HSM_1763 NC_010519.1 2007616 2008356 R PFAM: protein of unknown function DUF28; KEGG: hso:HS_0508 hypothetical protein; hypothetical protein complement(2007616..2008356) Haemophilus somnus 2336 6107681 YP_001785084.1 CDS ntpA NC_010519.1 2008358 2008810 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(2008358..2008810) Haemophilus somnus 2336 6107682 YP_001785085.1 CDS HSM_1765 NC_010519.1 2008964 2009296 R PFAM: protein of unknown function UPF0125; KEGG: hso:HS_0506 hypothetical protein; hypothetical protein complement(2008964..2009296) Haemophilus somnus 2336 6107683 YP_001785086.1 CDS HSM_1766 NC_010519.1 2009289 2009852 R PFAM: cyclase/dehydrase; KEGG: hso:HS_0505 hypothetical protein; cyclase/dehydrase complement(2009289..2009852) Haemophilus somnus 2336 6107684 YP_001785087.1 CDS HSM_1767 NC_010519.1 2009901 2010485 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 2009901..2010485 Haemophilus somnus 2336 6107685 YP_001785088.1 CDS HSM_1768 NC_010519.1 2010552 2011643 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 2010552..2011643 Haemophilus somnus 2336 6107686 YP_001785089.1 CDS HSM_1769 NC_010519.1 2011893 2012303 D TIGRFAM: lactoylglutathione lyase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: hso:HS_0502 lactoylglutathione lyase (glyoxalase I); lactoylglutathione lyase 2011893..2012303 Haemophilus somnus 2336 6107687 YP_001785090.1 CDS HSM_1770 NC_010519.1 2012391 2013047 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 2012391..2013047 Haemophilus somnus 2336 6107688 YP_001785091.1 CDS HSM_1771 NC_010519.1 2013097 2014500 R PFAM: multicopper oxidase type 3; KEGG: hso:HS_0500 suppressor of FtsI; multicopper oxidase type 3 complement(2013097..2014500) Haemophilus somnus 2336 6107690 YP_001785092.1 CDS HSM_1772 NC_010519.1 2014516 2015241 R TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; KEGG: hso:HS_0499 1-acylglycerol-3-phosphate O-acyltransferase (1-acyl-sn-glycerol-3-phosphate acyltransferase); 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(2014516..2015241) Haemophilus somnus 2336 6107691 YP_001785093.1 CDS HSM_1773 NC_010519.1 2015352 2016056 D catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 2015352..2016056 Haemophilus somnus 2336 6107692 YP_001785094.1 CDS uvrD NC_010519.1 2016122 2018302 R unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II complement(2016122..2018302) Haemophilus somnus 2336 6107693 YP_001785095.1 CDS HSM_1775 NC_010519.1 2018450 2019535 R KEGG: hso:HS_0496 conserved hypothetical protein; RNA 2'-O-ribose methyltransferase complement(2018450..2019535) Haemophilus somnus 2336 6107694 YP_001785096.1 CDS HSM_1776 NC_010519.1 2019528 2020421 R glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA complement(2019528..2020421) Haemophilus somnus 2336 6107695 YP_001785097.1 CDS HSM_1777 NC_010519.1 2020874 2021893 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 2020874..2021893 Haemophilus somnus 2336 6107696 YP_001785098.1 CDS bcp NC_010519.1 2021974 2022450 R bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase complement(2021974..2022450) Haemophilus somnus 2336 6107697 YP_001785099.1 CDS HSM_1779 NC_010519.1 2022560 2023456 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 2022560..2023456 Haemophilus somnus 2336 6107698 YP_001785100.1 CDS HSM_1780 NC_010519.1 2023759 2024355 D KEGG: hso:HS_0337 hypothetical protein; hypothetical protein 2023759..2024355 Haemophilus somnus 2336 6107699 YP_001785101.1 CDS rimI NC_010519.1 2024470 2024916 R alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase complement(2024470..2024916) Haemophilus somnus 2336 6107701 YP_001785102.1 CDS HSM_1782 NC_010519.1 2024920 2025324 R with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi complement(2024920..2025324) Haemophilus somnus 2336 6107702 YP_001785103.1 CDS HSM_1783 NC_010519.1 2025502 2027913 R KEGG: hso:HS_0489 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16; ATPase AAA central domain protein; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; ATP-dependent protease La complement(2025502..2027913) Haemophilus somnus 2336 6107703 YP_001785104.1 CDS HSM_1784 NC_010519.1 2028202 2029089 R TIGRFAM: HflC protein; PFAM: hypothetical protein; KEGG: hso:HS_0488 HflC protein; HflC protein complement(2028202..2029089) Haemophilus somnus 2336 6107704 YP_001785105.1 CDS HSM_1785 NC_010519.1 2029089 2030339 R TIGRFAM: HflK protein; PFAM: hypothetical protein; KEGG: hso:HS_0487 HflK protein; HflK protein complement(2029089..2030339) Haemophilus somnus 2336 6107705 YP_001785106.1 CDS HSM_1786 NC_010519.1 2030648 2031613 R catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(2030648..2031613) Haemophilus somnus 2336 6107706 YP_001785107.1 CDS HSM_1787 NC_010519.1 2031726 2032622 R TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: hso:HS_0484 cation efflux protein; cation diffusion facilitator family transporter complement(2031726..2032622) Haemophilus somnus 2336 6107707 YP_001785108.1 CDS HSM_1788 NC_010519.1 2032637 2033191 R KEGG: hso:HS_0483 hypothetical protein; hypothetical protein complement(2032637..2033191) Haemophilus somnus 2336 6107708 YP_001785109.1 CDS HSM_1789 NC_010519.1 2033188 2033964 R PFAM: protein of unknown function DUF328; KEGG: hso:HS_0482 hypothetical protein; hypothetical protein complement(2033188..2033964) Haemophilus somnus 2336 6107709 YP_001785110.1 CDS HSM_1790 NC_010519.1 2033980 2034651 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(2033980..2034651) Haemophilus somnus 2336 6107710 YP_001785111.1 CDS HSM_1791 NC_010519.1 2034911 2035294 D stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 2034911..2035294 Haemophilus somnus 2336 6107712 YP_001785112.1 CDS glyS NC_010519.1 2035397 2037463 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(2035397..2037463) Haemophilus somnus 2336 6107713 YP_001785113.1 CDS HSM_1793 NC_010519.1 2038316 2046592 D PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: hso:HS_1058 large adhesin; YadA domain-containing protein 2038316..2046592 Haemophilus somnus 2336 6107714 YP_001785114.1 CDS HSM_1794 NC_010519.1 2047245 2048180 D PFAM: glycosyltransferase family 52; KEGG: pmu:PM0508 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 3-sialyltransfera se; glycosyl transferase family protein 2047245..2048180 Haemophilus somnus 2336 6107715 YP_001785115.1 CDS HSM_1795 NC_010519.1 2048250 2048540 R KEGG: hso:HS_1633 conserved hypothetical protein; hypothetical protein complement(2048250..2048540) Haemophilus somnus 2336 6107716 YP_001785116.1 CDS HSM_1796 NC_010519.1 2048552 2048914 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC complement(2048552..2048914) Haemophilus somnus 2336 6107717 YP_001785117.1 CDS HSM_1797 NC_010519.1 2048911 2049291 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD complement(2048911..2049291) Haemophilus somnus 2336 6107718 YP_001785118.1 CDS HSM_1798 NC_010519.1 2049291 2049959 R PFAM: YheO domain protein; KEGG: hso:HS_1636 hypothetical protein; YheO domain-containing protein complement(2049291..2049959) Haemophilus somnus 2336 6107719 YP_001785119.1 CDS HSM_1799 NC_010519.1 2050028 2050714 R PFAM: peptidylprolyl isomerase FKBP-type; KEGG: hso:HS_1637 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase); FKBP-type peptidylprolyl isomerase complement(2050028..2050714) Haemophilus somnus 2336 6107720 YP_001785120.1 CDS HSM_1800 NC_010519.1 2050811 2051032 D PFAM: SlyX family protein; KEGG: hso:HS_1638 SlyX family protein; hypothetical protein 2050811..2051032 Haemophilus somnus 2336 6107721 YP_001785121.1 CDS HSM_1801 NC_010519.1 2051034 2051489 R PFAM: NUDIX hydrolase; KEGG: hso:HS_1639 NTP pyrophosphohydrolase, MutT/NUDIX family; NUDIX hydrolase complement(2051034..2051489) Haemophilus somnus 2336 6107724 YP_001785122.1 CDS HSM_1802 NC_010519.1 2051491 2052174 R PFAM: pseudouridine synthase; KEGG: hso:HS_1640 ribosomal large subunit pseudouridine synthase; pseudouridine synthase complement(2051491..2052174) Haemophilus somnus 2336 6107725 YP_001785123.1 CDS HSM_1803 NC_010519.1 2052225 2054438 R TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate dehydrogenase NADP-dependent monomeric type; KEGG: hso:HS_1641 isocitrate dehydrogenase; isocitrate dehydrogenase complement(2052225..2054438) Haemophilus somnus 2336 6107726 YP_001785124.1 CDS HSM_1804 NC_010519.1 2054653 2055831 D PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; KEGG: hso:HS_1642 hypothetical protein; ATP-dependent carboxylate-amine ligase domain-containing protein 2054653..2055831 Haemophilus somnus 2336 6107727 YP_001785125.1 CDS HSM_1805 NC_010519.1 2055892 2056644 D PFAM: esterase; KEGG: hso:HS_1643 hypothetical protein; esterase 2055892..2056644 Haemophilus somnus 2336 6107728 YP_001785126.1 CDS HSM_1806 NC_010519.1 2057099 2058283 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(2057099..2058283) Haemophilus somnus 2336 6107729 YP_001785127.1 CDS HSM_1807 NC_010519.1 2058355 2060457 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(2058355..2060457) Haemophilus somnus 2336 6107730 YP_001785128.1 CDS HSM_1808 NC_010519.1 2060547 2061017 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(2060547..2061017) Haemophilus somnus 2336 6107731 YP_001785129.1 CDS rpsL NC_010519.1 2061148 2061522 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(2061148..2061522) Haemophilus somnus 2336 6107732 YP_001785130.1 CDS hslO NC_010519.1 2061681 2062541 R becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin complement(2061681..2062541) Haemophilus somnus 2336 6107733 YP_001785131.1 CDS HSM_1811 NC_010519.1 2062597 2063007 R PFAM: RNA-binding S4 domain protein; KEGG: hso:HS_1649 heat shock protein 15; RNA-binding S4 domain-containing protein complement(2062597..2063007) Haemophilus somnus 2336 6107735 YP_001785132.1 CDS HSM_1812 NC_010519.1 2063079 2063897 D TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: hso:HS_1650 3'-phosphoadenosine 5'-phosphosulfate (PapS) 3'-phosphatase; 3'(2'),5'-bisphosphate nucleotidase 2063079..2063897 Haemophilus somnus 2336 6107736 YP_001785133.1 CDS HSM_1813 NC_010519.1 2063897 2065459 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2063897..2065459 Haemophilus somnus 2336 6107737 YP_001785134.1 CDS HSM_1814 NC_010519.1 2065510 2066214 D TIGRFAM: 6-phosphogluconolactonase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: hso:HS_1652 6-phosphogluconolactonase; 6-phosphogluconolactonase 2065510..2066214 Haemophilus somnus 2336 6107738 YP_001785135.1 CDS HSM_1815 NC_010519.1 2066247 2066675 D KEGG: hso:HS_1653 hypothetical protein; hypothetical protein 2066247..2066675 Haemophilus somnus 2336 6107739 YP_001785136.1 CDS HSM_1816 NC_010519.1 2066679 2068133 D catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2066679..2068133 Haemophilus somnus 2336 6107740 YP_001785137.1 CDS HSM_1817 NC_010519.1 2068302 2069051 D PFAM: VacJ family lipoprotein; KEGG: hso:HS_1655 VacJ lipoprotein; VacJ family lipoprotein 2068302..2069051 Haemophilus somnus 2336 6107741 YP_001785138.1 CDS HSM_1818 NC_010519.1 2069071 2069565 D PFAM: YfbU family protein; KEGG: hso:HS_1656 hypothetical protein; hypothetical protein 2069071..2069565 Haemophilus somnus 2336 6107742 YP_001785139.1 CDS HSM_1819 NC_010519.1 2069615 2069914 R PFAM: protein of unknown function DUF167; KEGG: hso:HS_1657 conserved hypothetical protein; hypothetical protein complement(2069615..2069914) Haemophilus somnus 2336 6107743 YP_001785140.1 CDS HSM_1820 NC_010519.1 2069940 2070497 R PFAM: protein of unknown function YGGT; KEGG: hso:HS_1658 conserved hypothetical protein; hypothetical protein complement(2069940..2070497) Haemophilus somnus 2336 6107744 YP_001785141.1 CDS HSM_1821 NC_010519.1 2070497 2071447 R responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA complement(2070497..2071447) Haemophilus somnus 2336 6107746 YP_001785142.1 CDS HSM_1822 NC_010519.1 2071781 2072119 R PFAM: protein of unknown function DUF469; KEGG: hso:HS_1661 hypothetical protein; hypothetical protein complement(2071781..2072119) Haemophilus somnus 2336 6107747 YP_001785143.1 CDS HSM_1823 NC_010519.1 2072217 2073101 R PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: hso:HS_1662 transcription regulator, LysR family; LysR family transcriptional regulator complement(2072217..2073101) Haemophilus somnus 2336 6107748 YP_001785144.1 CDS HSM_1826 NC_010519.1 2074705 2075304 D PFAM: phosphoglycerate mutase; KEGG: hso:HS_1664 phosphoglycerate mutase; phosphoglycerate mutase 2074705..2075304 Haemophilus somnus 2336 6107750 YP_001785145.1 CDS HSM_1827 NC_010519.1 2075444 2075893 R PFAM: protein of unknown function DUF302; KEGG: hso:HS_1665 hypothetical protein; hypothetical protein complement(2075444..2075893) Haemophilus somnus 2336 6107751 YP_001785146.1 CDS trmB NC_010519.1 2075905 2076660 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(2075905..2076660) Haemophilus somnus 2336 6107752 YP_001785147.1 CDS HSM_1829 NC_010519.1 2076806 2077918 D TIGRFAM: A/G-specific adenine glycosylase; PFAM: HhH-GPD family protein; KEGG: hso:HS_1667 A/G-specific adenine glycosylase; A/G-specific adenine glycosylase 2076806..2077918 Haemophilus somnus 2336 6107753 YP_001785148.1 CDS HSM_1830 NC_010519.1 2077921 2078196 D PFAM: Fe(II) trafficking protein YggX; KEGG: hso:HS_1668 hypothetical protein; hypothetical protein 2077921..2078196 Haemophilus somnus 2336 6107754 YP_001785149.1 CDS mltC NC_010519.1 2078203 2079294 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 2078203..2079294 Haemophilus somnus 2336 6107756 YP_001785150.1 CDS HSM_1832 NC_010519.1 2079389 2081044 D PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: hso:HS_1670 phosphomannomutase; phosphoglucomutase/phosphomannomutase subunit alpha/beta 2079389..2081044 Haemophilus somnus 2336 6107757 YP_001785151.1 CDS HSM_1833 NC_010519.1 2081173 2082654 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(2081173..2082654) Haemophilus somnus 2336 6107758 YP_001785152.1 CDS HSM_1834 NC_010519.1 2082909 2084078 D TIGRFAM: trimethylamine-N-oxide reductase c-type cytochrome TorC; PFAM: NapC/NirT cytochrome C domain protein; KEGG: hso:HS_1672 cytochrome C protein; trimethylamine-N-oxide reductase c-type cytochrome TorC 2082909..2084078 Haemophilus somnus 2336 6107759 YP_001785153.1 CDS HSM_1835 NC_010519.1 2084093 2086561 D TIGRFAM: trimethylamine-N-oxide reductase TorA; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: hso:HS_1673 trimethylamine-N-oxide reductase precursor; trimethylamine-N-oxide reductase TorA 2084093..2086561 Haemophilus somnus 2336 6107760 YP_001785154.1 CDS torD NC_010519.1 2086558 2087151 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 2086558..2087151 Haemophilus somnus 2336 6107761 YP_001785155.1 CDS mnmA NC_010519.1 2087235 2088386 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(2087235..2088386) Haemophilus somnus 2336 6107762 YP_001785156.1 CDS HSM_1838 NC_010519.1 2088421 2088933 R KEGG: hso:HS_1684 Haemophilus-specific protein, uncharacterized; hypothetical protein complement(2088421..2088933) Haemophilus somnus 2336 6107763 YP_001785157.1 CDS HSM_1839 NC_010519.1 2088973 2089227 R PFAM: protein of unknown function DUF539; KEGG: hso:HS_1685 hypothetical protein; hypothetical protein complement(2088973..2089227) Haemophilus somnus 2336 6107764 YP_001785158.1 CDS HSM_1840 NC_010519.1 2089237 2090286 R PFAM: ApbE family lipoprotein; KEGG: hso:HS_1686 thiamine biosynthesis lipoprotein; ApbE family lipoprotein complement(2089237..2090286) Haemophilus somnus 2336 6107765 YP_001785159.1 CDS HSM_1841 NC_010519.1 2090302 2090814 R TIGRFAM: peptide methionine sulfoxide reductase; PFAM: methionine sulfoxide reductase A; KEGG: hso:HS_1687 peptide methionine sulfoxide reductase MsrA/MsrB; peptide methionine sulfoxide reductase complement(2090302..2090814) Haemophilus somnus 2336 6107767 YP_001785160.1 CDS HSM_1842 NC_010519.1 2090917 2092140 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F complement(2090917..2092140) Haemophilus somnus 2336 6107768 YP_001785161.1 CDS HSM_1843 NC_010519.1 2092155 2092751 R Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.; Na(+)-translocating NADH-quinone reductase subunit E complement(2092155..2092751) Haemophilus somnus 2336 6107769 YP_001785162.1 CDS HSM_1844 NC_010519.1 2092755 2093378 R Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D complement(2092755..2093378) Haemophilus somnus 2336 6107770 YP_001785163.1 CDS HSM_1845 NC_010519.1 2093378 2094154 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C complement(2093378..2094154) Haemophilus somnus 2336 6107771 YP_001785164.1 CDS HSM_1846 NC_010519.1 2094147 2095385 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B complement(2094147..2095385) Haemophilus somnus 2336 6107772 YP_001785165.1 CDS HSM_1847 NC_010519.1 2095388 2096728 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A complement(2095388..2096728) Haemophilus somnus 2336 6107773 YP_001785166.1 CDS HSM_1848 NC_010519.1 2097056 2097367 R PFAM: BolA family protein; KEGG: hso:HS_1694 BolA protein; BolA family protein complement(2097056..2097367) Haemophilus somnus 2336 6107774 YP_001785167.1 CDS atpC NC_010519.1 2097556 2097984 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(2097556..2097984) Haemophilus somnus 2336 6107775 YP_001785168.1 CDS HSM_1850 NC_010519.1 2098027 2099400 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(2098027..2099400) Haemophilus somnus 2336 6107776 YP_001785169.1 CDS HSM_1851 NC_010519.1 2099414 2100283 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(2099414..2100283) Haemophilus somnus 2336 6107778 YP_001785170.1 CDS HSM_1852 NC_010519.1 2100307 2101848 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(2100307..2101848) Haemophilus somnus 2336 6107779 YP_001785171.1 CDS HSM_1853 NC_010519.1 2101861 2102409 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the subunit delta is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(2101861..2102409) Haemophilus somnus 2336 6107780 YP_001785172.1 CDS HSM_1854 NC_010519.1 2102423 2102893 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit beta complement(2102423..2102893) Haemophilus somnus 2336 6107781 YP_001785173.1 CDS HSM_1855 NC_010519.1 2102958 2103212 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit chi complement(2102958..2103212) Haemophilus somnus 2336 6107782 YP_001785174.1 CDS HSM_1856 NC_010519.1 2103311 2104108 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit alpha complement(2103311..2104108) Haemophilus somnus 2336 6107783 YP_001785175.1 CDS gidB NC_010519.1 2104620 2105282 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(2104620..2105282) Haemophilus somnus 2336 6107784 YP_001785176.1 CDS HSM_1858 NC_010519.1 2105282 2107171 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(2105282..2107171) Haemophilus somnus 2336 6107785 YP_001785177.1 CDS HSM_1859 NC_010519.1 2107551 2108000 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(2107551..2108000) Haemophilus somnus 2336 6107786 YP_001785178.1 CDS HSM_1860 NC_010519.1 2108067 2108285 R PFAM: protein of unknown function DUF904; KEGG: hso:HS_1707 hypothetical protein; hypothetical protein complement(2108067..2108285) Haemophilus somnus 2336 6107787 YP_001785179.1 CDS gyrB NC_010519.1 2108540 2110963 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 2108540..2110963 Haemophilus somnus 2336 6107789 YP_001785180.1 CDS HSM_1862 NC_010519.1 2111328 2113202 R TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase; HRDC domain protein; DEAD/DEAH box helicase; SMART: DEAD-like helicases; KEGG: hso:HS_1711 ATP-dependent DNA helicase; ATP-dependent DNA helicase RecQ complement(2111328..2113202) Haemophilus somnus 2336 6107790 YP_001785181.1 CDS cyaY NC_010519.1 2113202 2113510 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(2113202..2113510) Haemophilus somnus 2336 6107791 YP_001785182.1 CDS HSM_1864 NC_010519.1 2113635 2113766 D KEGG: hit:NTHI0885 hypothetical protein; hypothetical protein 2113635..2113766 Haemophilus somnus 2336 6107792 YP_001785183.1 CDS HSM_1865 NC_010519.1 2113788 2115041 D TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: hso:HS_1713 diaminopimelate decarboxylase; diaminopimelate decarboxylase 2113788..2115041 Haemophilus somnus 2336 6107793 YP_001785184.1 CDS HSM_1866 NC_010519.1 2115305 2116813 D PFAM: sodium:neurotransmitter symporter; KEGG: hso:HS_1714 sodium-dependent transporter (SNF family); sodium:neurotransmitter symporter 2115305..2116813 Haemophilus somnus 2336 6107794 YP_001785185.1 CDS HSM_1867 NC_010519.1 2117343 2117993 R PFAM: TfoX domain protein; KEGG: hso:HS_1715 DNA transformation protein; competence-specific genes regulator complement(2117343..2117993) Haemophilus somnus 2336 6107795 YP_001785186.1 CDS HSM_1868 NC_010519.1 2124060 2124680 R PFAM: LysR substrate-binding; KEGG: hso:HS_1716 D-serine dehydratase (deaminase) transcriptional activator; LysR family transcriptional regulator complement(2124060..2124680) Haemophilus somnus 2336 6108900 YP_001785187.1 CDS HSM_1869 NC_010519.1 2124957 2125664 R PFAM: helix-turn-helix domain protein; peptidase S24 S26A and S26B; KEGG: hdu:HD0089 probable transcription regulator; phage repressor complement(2124957..2125664) Haemophilus somnus 2336 6107797 YP_001785188.1 CDS HSM_1870 NC_010519.1 2125849 2126118 D KEGG: hdu:HD0090 DNA-binding protein; Nlp family transcripitonal regulator 2125849..2126118 Haemophilus somnus 2336 6107798 YP_001785189.1 CDS HSM_1871 NC_010519.1 2126129 2128087 D PFAM: Integrase catalytic region; transposase-like Mu; KEGG: sfx:S2951 phage transposase; transposase 2126129..2128087 Haemophilus somnus 2336 6107800 YP_001785190.1 CDS HSM_1874 NC_010519.1 2129292 2130413 R KEGG: hdu:HD1689 transposase; transposase complement(2129292..2130413) Haemophilus somnus 2336 6107802 YP_001785191.1 CDS HSM_1875 NC_010519.1 2130790 2131287 R hypothetical protein complement(2130790..2131287) Haemophilus somnus 2336 6107803 YP_001785192.1 CDS HSM_1876 NC_010519.1 2131621 2132025 D PFAM: helix-turn-helix domain protein; KEGG: hit:NTHI0420 hypothetical protein; helix-turn-helix domain-containing protein 2131621..2132025 Haemophilus somnus 2336 6107804 YP_001785193.1 CDS HSM_1877 NC_010519.1 2132108 2133055 D KEGG: hdu:HD1543 hypothetical protein; hypothetical protein 2132108..2133055 Haemophilus somnus 2336 6107805 YP_001785194.1 CDS HSM_1878 NC_010519.1 2133039 2133500 D KEGG: hdu:HD1546 hypothetical protein; hypothetical protein 2133039..2133500 Haemophilus somnus 2336 6107806 YP_001785195.1 CDS HSM_1879 NC_010519.1 2133840 2134235 R hypothetical protein complement(2133840..2134235) Haemophilus somnus 2336 6107807 YP_001785196.1 CDS HSM_1880 NC_010519.1 2134346 2135887 R PFAM: N-6 DNA methylase; KEGG: fth:FTH_0955 type I site-specific deoxyribonuclease; N-6 DNA methylase complement(2134346..2135887) Haemophilus somnus 2336 6107808 YP_001785197.1 CDS HSM_1881 NC_010519.1 2135847 2136245 R hypothetical protein complement(2135847..2136245) Haemophilus somnus 2336 6107810 YP_001785198.1 CDS HSM_1882 NC_010519.1 2136356 2136550 R KEGG: hdu:HD1613 hypothetical protein; hypothetical protein complement(2136356..2136550) Haemophilus somnus 2336 6107811 YP_001785199.1 CDS HSM_1883 NC_010519.1 2136849 2137502 D KEGG: hso:HS_1709 transposase; transposase 2136849..2137502 Haemophilus somnus 2336 6107812 YP_001785200.1 CDS HSM_1886 NC_010519.1 2138784 2139098 D KEGG: hdu:HD1611 hypothetical protein; hypothetical protein 2138784..2139098 Haemophilus somnus 2336 6107814 YP_001785201.1 CDS HSM_1887 NC_010519.1 2139228 2139476 D KEGG: bxe:Bxe_A1012 transposase; transposase 2139228..2139476 Haemophilus somnus 2336 6107815 YP_001785202.1 CDS HSM_1888 NC_010519.1 2139936 2141045 D PFAM: ATPase AAA; SMART: AAA ATPase; KEGG: reu:Reut_C6418 ATPase AAA, central region; ATPase 2139936..2141045 Haemophilus somnus 2336 6107816 YP_001785203.1 CDS HSM_1889 NC_010519.1 2141042 2143234 D PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: reu:Reut_C6419 peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase S8/S53 subtilisin kexin sedolisin 2141042..2143234 Haemophilus somnus 2336 6107817 YP_001785204.1 CDS HSM_1890 NC_010519.1 2143369 2143800 R KEGG: hdu:HD1698 hypothetical protein; hypothetical protein complement(2143369..2143800) Haemophilus somnus 2336 6107818 YP_001785205.1 CDS HSM_1891 NC_010519.1 2143886 2144419 D PFAM: gluconate transporter; KEGG: hso:HS_1717 D-serine permease; gluconate transporter 2143886..2144419 Haemophilus somnus 2336 6107820 YP_001785206.1 CDS HSM_1892 NC_010519.1 2144430 2145746 D catalyzes the formation of pyruvate from serine; D-serine dehydratase 2144430..2145746 Haemophilus somnus 2336 6107821 YP_001785207.1 CDS HSM_1893 NC_010519.1 2146603 2148000 D PFAM: Nicotinate phosphoribosyltransferase and related; KEGG: hso:HS_0002 nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase 2146603..2148000 Haemophilus somnus 2336 6108902 YP_001785208.1 CDS HSM_1894 NC_010519.1 2148077 2148541 R catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase complement(2148077..2148541) Haemophilus somnus 2336 6107823 YP_001785209.1 CDS HSM_1895 NC_010519.1 2148666 2150126 D TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: hso:HS_0004 Xaa-His dipeptidase (aminoacyl-histidine dipeptidase); aminoacyl-histidine dipeptidase 2148666..2150126 Haemophilus somnus 2336 6107824 YP_001785210.1 CDS HSM_1896 NC_010519.1 2150274 2152853 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(2150274..2152853) Haemophilus somnus 2336 6107825 YP_001785211.1 CDS aroE NC_010519.1 2152986 2153801 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(2152986..2153801) Haemophilus somnus 2336 6107826 YP_001785212.1 CDS HSM_1898 NC_010519.1 2153805 2154356 R PFAM: SUA5/yciO/yrdC domain; KEGG: hso:HS_0007 translation factor, SUA5 family; SUA5/yciO/yrdC domain-containing protein complement(2153805..2154356) Haemophilus somnus 2336 6107827 YP_001785213.1 CDS HSM_1899 NC_010519.1 2154353 2154901 R PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: hso:HS_0008 DNA topoisomerase I-related protein; DNA topoisomerase type IA Zn finger domain-containing protein complement(2154353..2154901) Haemophilus somnus 2336 6107828 YP_001785214.1 CDS HSM_1900 NC_010519.1 2155035 2155598 D PFAM: protein of unknown function DUF179; KEGG: hso:HS_0009 conserved hypothetical protein; hypothetical protein 2155035..2155598 Haemophilus somnus 2336 6107829 YP_001785215.1 CDS HSM_1901 NC_010519.1 2155598 2156023 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 2155598..2156023 Haemophilus somnus 2336 6107831 YP_001785216.1 CDS HSM_1902 NC_010519.1 2156024 2156782 R PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: hso:HS_0011 transcriptional regulator of sugar metabolism; DeoR family transcriptional regulator complement(2156024..2156782) Haemophilus somnus 2336 6107832 YP_001785217.1 CDS HSM_1903 NC_010519.1 2156953 2157861 D PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: hso:HS_0012 3-hydroxyisobutyrate dehydrogenase family protein; 3-hydroxyisobutyrate dehydrogenase 2156953..2157861 Haemophilus somnus 2336 6107833 YP_001785218.1 CDS HSM_1904 NC_010519.1 2157863 2159104 D PFAM: type III effector Hrp-dependent outers; KEGG: hso:HS_0013 secretion system component; Hrp-dependent type III effector protein 2157863..2159104 Haemophilus somnus 2336 6107834 YP_001785219.1 CDS HSM_1905 NC_010519.1 2159101 2159733 D PFAM: class II aldolase/adducin family protein; KEGG: hso:HS_0014 L-fuculose-phosphate aldolase, aldolase class II family; aldolase 2159101..2159733 Haemophilus somnus 2336 6107835 YP_001785220.1 CDS HSM_1906 NC_010519.1 2159736 2160518 D PFAM: xylose isomerase; KEGG: hso:HS_0015 hydroxypyruvate isomerase; hydroxypyruvate isomerase 2159736..2160518 Haemophilus somnus 2336 6107836 YP_001785221.1 CDS HSM_1907 NC_010519.1 2160533 2161207 D PFAM: cyclase family protein; KEGG: pmu:PM1362 hypothetical T. maritima; cyclase family protein 2160533..2161207 Haemophilus somnus 2336 6107837 YP_001785222.1 CDS HSM_1908 NC_010519.1 2161209 2163008 D KEGG: pmu:PM1361 kmt1; hypothetical protein 2161209..2163008 Haemophilus somnus 2336 6107838 YP_001785223.1 CDS HSM_1909 NC_010519.1 2163153 2164100 D PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: hso:HS_0016 hypothetical protein; NAD-dependent epimerase/dehydratase 2163153..2164100 Haemophilus somnus 2336 6107839 YP_001785224.1 CDS HSM_1910 NC_010519.1 2164116 2165588 D TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter; KEGG: hso:HS_0017 GntP family permease (gluconate uptake protein); gluconate transporter 2164116..2165588 Haemophilus somnus 2336 6107840 YP_001785225.1 CDS HSM_1911 NC_010519.1 2166197 2167240 D PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: hso:HS_0018 hypothetical protein; UBA/THIF-type NAD/FAD binding protein 2166197..2167240 Haemophilus somnus 2336 6107842 YP_001785226.1 CDS HSM_1912 NC_010519.1 2167227 2168402 D PFAM: major facilitator superfamily MFS_1; KEGG: hso:HS_0019 permease, major facilitator superfamily; major facilitator transporter 2167227..2168402 Haemophilus somnus 2336 6107843 YP_001785227.1 CDS HSM_1913 NC_010519.1 2168700 2169449 R PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: hso:HS_0020 uxu operon regulator; GntR family transcriptional regulator complement(2168700..2169449) Haemophilus somnus 2336 6107844 YP_001785228.1 CDS HSM_1914 NC_010519.1 2169611 2170636 D PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: hso:HS_0021 Zn-binding dehydrogenase; alcohol dehydrogenase 2169611..2170636 Haemophilus somnus 2336 6107845 YP_001785229.1 CDS HSM_1915 NC_010519.1 2170665 2171648 D TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: hso:HS_0022 dicarboxylate-binding protein; TRAP dicarboxylate transporter subunit DctP 2170665..2171648 Haemophilus somnus 2336 6107846 YP_001785230.1 CDS HSM_1916 NC_010519.1 2171713 2172192 D PFAM: tripartite ATP-independent periplasmic transporter DctQ component; KEGG: hso:HS_0023 permease (transporter); tripartite ATP-independent periplasmic transporter DctQ 2171713..2172192 Haemophilus somnus 2336 6107847 YP_001785231.1 CDS HSM_1917 NC_010519.1 2172189 2173463 D TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: hso:HS_0024 permease (transporter); TRAP dicarboxylate transporter subunit DctM 2172189..2173463 Haemophilus somnus 2336 6107848 YP_001785232.1 CDS HSM_1918 NC_010519.1 2173650 2174297 D PFAM: allophanate hydrolase subunit 1; KEGG: hso:HS_0025 allophanate hydrolase, subunit 1; allophanate hydrolase subunit 1 2173650..2174297 Haemophilus somnus 2336 6107849 YP_001785233.1 CDS HSM_1919 NC_010519.1 2174294 2175223 D TIGRFAM: urea amidolyase related protein; PFAM: allophanate hydrolase subunit 2; KEGG: hso:HS_0026 allophanate hydrolase, subunit 2; urea amidolyase-like protein 2174294..2175223 Haemophilus somnus 2336 6107850 YP_001785234.1 CDS HSM_1920 NC_010519.1 2175210 2175953 D PFAM: LamB/YcsF family protein; KEGG: hso:HS_0027 lactam utilization protein; LamB/YcsF family protein 2175210..2175953 Haemophilus somnus 2336 6107851 YP_001785235.1 CDS HSM_1921 NC_010519.1 2176079 2177266 D KEGG: hso:HS_0028 permease (transporter); permease 2176079..2177266 Haemophilus somnus 2336 6107853 YP_001785236.1 CDS HSM_1922 NC_010519.1 2177378 2178238 D positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 2177378..2178238 Haemophilus somnus 2336 6107854 YP_001785237.1 CDS HSM_1923 NC_010519.1 2178426 2179400 D KEGG: hso:HS_0030 sugar ABC transporter sugar-binding protein; sugar ABC transporter sugar-binding protein 2178426..2179400 Haemophilus somnus 2336 6107855 YP_001785238.1 CDS HSM_1924 NC_010519.1 2179453 2180943 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0031 sugar ABC transporter ATP-binding; ABC transporter 2179453..2180943 Haemophilus somnus 2336 6107856 YP_001785239.1 CDS HSM_1925 NC_010519.1 2180927 2181886 D PFAM: inner-membrane translocator; KEGG: hso:HS_0032 sugar ABC transporter permease; monosaccharide-transporting ATPase 2180927..2181886 Haemophilus somnus 2336 6107857 YP_001785240.1 CDS HSM_1926 NC_010519.1 2181889 2182839 D PFAM: inner-membrane translocator; KEGG: hso:HS_0033 sugar ABC transporter permease; monosaccharide-transporting ATPase 2181889..2182839 Haemophilus somnus 2336 6107858 YP_001785241.1 CDS HSM_1927 NC_010519.1 2182852 2184444 D PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_0034 sugar kinase; carbohydrate kinase FGGY 2182852..2184444 Haemophilus somnus 2336 6107859 YP_001785242.1 CDS HSM_1928 NC_010519.1 2184566 2185288 R TIGRFAM: glutaredoxin-family domain protein; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; glutaredoxin; redoxin; KEGG: hso:HS_0035 peroxiredoxin; glutaredoxin family protein complement(2184566..2185288) Haemophilus somnus 2336 6107860 YP_001785243.1 CDS HSM_1929 NC_010519.1 2185411 2186325 D Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 2185411..2186325 Haemophilus somnus 2336 6107861 YP_001785244.1 CDS mscL NC_010519.1 2186452 2186847 R forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel complement(2186452..2186847) Haemophilus somnus 2336 6107862 YP_001785245.1 CDS trkA NC_010519.1 2186932 2188308 R involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein complement(2186932..2188308) Haemophilus somnus 2336 6107864 YP_001785246.1 CDS HSM_1932 NC_010519.1 2188393 2189781 R TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: hso:HS_0039 ribosomal RNA small subunit methyltransferase B; sun protein complement(2188393..2189781) Haemophilus somnus 2336 6107865 YP_001785247.1 CDS fmt NC_010519.1 2189778 2190731 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(2189778..2190731) Haemophilus somnus 2336 6107866 YP_001785248.1 CDS def NC_010519.1 2190806 2191318 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(2190806..2191318) Haemophilus somnus 2336 6107867 YP_001785249.1 CDS HSM_1935 NC_010519.1 2191505 2192134 R PFAM: regulatory protein LuxR; response regulator receiver; KEGG: hso:HS_0042 nitrate/nitrite response regulator protein; LuxR family transcriptional regulator complement(2191505..2192134) Haemophilus somnus 2336 6107868 YP_001785250.1 CDS cyaA NC_010519.1 2192149 2194659 R catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase complement(2192149..2194659) Haemophilus somnus 2336 6107869 YP_001785251.1 CDS hemC NC_010519.1 2194814 2195779 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 2194814..2195779 Haemophilus somnus 2336 6107870 YP_001785252.1 CDS HSM_1938 NC_010519.1 2195794 2196534 D PFAM: uroporphyrinogen III synthase HEM4; KEGG: hso:HS_0045 uroporphyrinogen-III synthase; uroporphyrinogen III synthase HEM4 2195794..2196534 Haemophilus somnus 2336 6107871 YP_001785253.1 CDS HSM_1939 NC_010519.1 2196570 2197934 D PFAM: protein of unknown function DUF513 hemX; KEGG: hso:HS_0046 uroporphyrin-III C-methyltransferase; hypothetical protein 2196570..2197934 Haemophilus somnus 2336 6107872 YP_001785254.1 CDS HSM_1940 NC_010519.1 2197949 2199226 D TIGRFAM: HemY protein; PFAM: HemY domain protein; KEGG: hso:HS_0047 porphyrin biosynthesis protein; HemY protein 2197949..2199226 Haemophilus somnus 2336 6107873 YP_001785255.1 CDS HSM_1941 NC_010519.1 2199281 2200267 R TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase; KEGG: hso:HS_0048 tRNA-dihydrouridine synthase A; tRNA-dihydrouridine synthase A complement(2199281..2200267) Haemophilus somnus 2336 6107875 YP_001785256.1 CDS HSM_1942 NC_010519.1 2200678 2202252 R PFAM: carbohydrate kinase FGGY; KEGG: hso:HS_0049 sugar kinase, FGGY family; autoinducer-2 (AI-2) kinase complement(2200678..2202252) Haemophilus somnus 2336 6107876 YP_001785257.1 CDS HSM_1943 NC_010519.1 2202285 2203244 R PFAM: sugar-binding domain protein; KEGG: hso:HS_0050 transcriptional regulator, sorbitol operon regulator; DeoR family transcriptional regulator complement(2202285..2203244) Haemophilus somnus 2336 6107877 YP_001785258.1 CDS HSM_1944 NC_010519.1 2203461 2204969 D PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hso:HS_0051 ABC transporter ATP-binding, sugar transport; ABC transporter 2203461..2204969 Haemophilus somnus 2336 6107878 YP_001785259.1 CDS HSM_1945 NC_010519.1 2204978 2205976 D PFAM: inner-membrane translocator; KEGG: hso:HS_0052 ABC transporter permease, sugar transport; monosaccharide-transporting ATPase 2204978..2205976 Haemophilus somnus 2336 6107879 YP_001785260.1 CDS HSM_1946 NC_010519.1 2205973 2206956 D PFAM: inner-membrane translocator; KEGG: hso:HS_0053 ABC transporter permease, sugar transport; monosaccharide-transporting ATPase 2205973..2206956 Haemophilus somnus 2336 6107880 YP_001785261.1 CDS HSM_1947 NC_010519.1 2207069 2208088 D KEGG: hso:HS_0054 sugar ABC transporter substrate-binding protein; sugar ABC transporter substrate-binding protein 2207069..2208088 Haemophilus somnus 2336 6107881 YP_001785262.1 CDS HSM_1948 NC_010519.1 2208107 2208985 D PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: hso:HS_0055 conserved aldolase; aldolase 2208107..2208985 Haemophilus somnus 2336 6107882 YP_001785263.1 CDS HSM_1949 NC_010519.1 2209051 2209353 D PFAM: antibiotic biosynthesis monooxygenase; KEGG: hso:HS_0056 hypothetical protein; autoinducer-2 (AI-2) modifying protein LsrG 2209051..2209353 Haemophilus somnus 2336 6107883 YP_001785264.1 CDS HSM_1950 NC_010519.1 2209346 2210056 D catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 2209346..2210056 Haemophilus somnus 2336 6107884 YP_001785265.1 CDS HSM_1951 NC_010519.1 2210318 2210629 D PFAM: ribosomal protein S10; KEGG: yps:YPTB3699 30S ribosomal protein S10; 30S ribosomal protein S10 2210318..2210629 Haemophilus somnus 2336 6107886 YP_001785266.1 CDS rplC NC_010519.1 2210646 2211272 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 2210646..2211272 Haemophilus somnus 2336 6107887 YP_001785267.1 CDS rplD NC_010519.1 2211288 2211890 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 2211288..2211890 Haemophilus somnus 2336 6107888 YP_001785268.1 CDS rplW NC_010519.1 2211887 2212192 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 2211887..2212192 Haemophilus somnus 2336 6107889 YP_001785269.1 CDS rplB NC_010519.1 2212213 2213034 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 2212213..2213034 Haemophilus somnus 2336 6107890 YP_001785270.1 CDS rpsS NC_010519.1 2213061 2213336 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 2213061..2213336 Haemophilus somnus 2336 6107891 YP_001785271.1 CDS rplV NC_010519.1 2213347 2213679 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 2213347..2213679 Haemophilus somnus 2336 6107892 YP_001785272.1 CDS rpsC NC_010519.1 2213696 2214403 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 2213696..2214403 Haemophilus somnus 2336 6107893 YP_001785273.1 CDS rplP NC_010519.1 2214417 2214827 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 2214417..2214827 Haemophilus somnus 2336 6107894 YP_001785274.1 CDS HSM_1960 NC_010519.1 2214827 2215018 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 2214827..2215018 Haemophilus somnus 2336 6107895 YP_001785275.1 CDS rpsQ NC_010519.1 2215018 2215272 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 2215018..2215272 Haemophilus somnus 2336 6107897 YP_001785276.1 CDS HSM_1962 NC_010519.1 2215469 2218075 D PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0069 iron-regulated outer membrane protein; TonB-dependent receptor 2215469..2218075 Haemophilus somnus 2336 6107898 YP_001785277.1 CDS rplN NC_010519.1 2218272 2218643 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 2218272..2218643 Haemophilus somnus 2336 6107899 YP_001785278.1 CDS rplX NC_010519.1 2218656 2218967 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 2218656..2218967 Haemophilus somnus 2336 6107900 YP_001785279.1 CDS rplE NC_010519.1 2218985 2219524 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 2218985..2219524 Haemophilus somnus 2336 6107901 YP_001785280.1 CDS rpsN NC_010519.1 2219536 2219841 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 2219536..2219841 Haemophilus somnus 2336 6107902 YP_001785281.1 CDS rpsH NC_010519.1 2219878 2220270 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 2219878..2220270 Haemophilus somnus 2336 6107903 YP_001785282.1 CDS rplF NC_010519.1 2220287 2220820 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 2220287..2220820 Haemophilus somnus 2336 6107904 YP_001785283.1 CDS rplR NC_010519.1 2220834 2221187 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 2220834..2221187 Haemophilus somnus 2336 6107905 YP_001785284.1 CDS rpsE NC_010519.1 2221203 2221703 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 2221203..2221703 Haemophilus somnus 2336 6107906 YP_001785285.1 CDS rpmD NC_010519.1 2221707 2221889 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 2221707..2221889 Haemophilus somnus 2336 6107908 YP_001785286.1 CDS rplO NC_010519.1 2221894 2222328 D late assembly protein; 50S ribosomal protein L15 2221894..2222328 Haemophilus somnus 2336 6107909 YP_001785287.1 CDS secY NC_010519.1 2222336 2223661 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 2222336..2223661 Haemophilus somnus 2336 6107910 YP_001785288.1 CDS rpmJ NC_010519.1 2223689 2223802 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 2223689..2223802 Haemophilus somnus 2336 6107911 YP_001785289.1 CDS rpsM NC_010519.1 2223946 2224302 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 2223946..2224302 Haemophilus somnus 2336 6107912 YP_001785290.1 CDS HSM_1976 NC_010519.1 2224318 2224707 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 2224318..2224707 Haemophilus somnus 2336 6107913 YP_001785291.1 CDS rpsD NC_010519.1 2224737 2225357 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 2224737..2225357 Haemophilus somnus 2336 6107914 YP_001785292.1 CDS HSM_1978 NC_010519.1 2225390 2226379 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 2225390..2226379 Haemophilus somnus 2336 6107915 YP_001785293.1 CDS rplQ NC_010519.1 2226421 2226807 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 2226421..2226807 Haemophilus somnus 2336 6107916 YP_001785294.1 CDS HSM_1980 NC_010519.1 2226877 2227563 R PFAM: metallophosphoesterase; KEGG: hso:HS_0086 hypothetical protein; metallophosphoesterase complement(2226877..2227563) Haemophilus somnus 2336 6107917 YP_001785295.1 CDS HSM_1981 NC_010519.1 2227568 2228845 R catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase complement(2227568..2228845) Haemophilus somnus 2336 6107919 YP_001785296.1 CDS HSM_1982 NC_010519.1 2228919 2229158 R PFAM: protein of unknown function DUF526; KEGG: hso:HS_0088 hypothetical protein; hypothetical protein complement(2228919..2229158) Haemophilus somnus 2336 6107920 YP_001785297.1 CDS ribB NC_010519.1 2229506 2230150 D DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 2229506..2230150 Haemophilus somnus 2336 6107921 YP_001785298.1 CDS recO NC_010519.1 2230381 2231034 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2230381..2231034 Haemophilus somnus 2336 6107922 YP_001785299.1 CDS rumA NC_010519.1 2231055 2232374 D in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 2231055..2232374 Haemophilus somnus 2336 6107923 YP_001785300.1 CDS HSM_1986 NC_010519.1 2232386 2234623 D TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; RelA/SpoT domain protein; KEGG: hso:HS_0095 GTP diphosphokinase (GTP pyrophosphokinase); (p)ppGpp synthetase I SpoT/RelA 2232386..2234623 Haemophilus somnus 2336 6107924 YP_001785301.1 CDS HSM_1987 NC_010519.1 2234654 2235010 D PFAM: diacylglycerol kinase; KEGG: hso:HS_0096 diacylglycerol kinase (diglyceride kinase); diacylglycerol kinase 2234654..2235010 Haemophilus somnus 2336 6107925 YP_001785302.1 CDS HSM_1988 NC_010519.1 2235057 2237303 R TIGRFAM: TonB-dependent lactoferrin and transferrin receptors; TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: hso:HS_0582 transferrin binding protein A; TonB-dependent lactoferrin and transferrin receptor complement(2235057..2237303) Haemophilus somnus 2336 6107926 YP_001785303.1 CDS HSM_1989 NC_010519.1 2237622 2238089 D KEGG: hso:HS_0104 hypothetical protein; hypothetical protein 2237622..2238089 Haemophilus somnus 2336 6107927 YP_001785304.1 CDS HSM_1990 NC_010519.1 2238116 2239333 D PFAM: beta-ketoacyl synthase; KEGG: hso:HS_0105 3-oxoacyl-[acyl-carrier-protein] synthase (beta-ketoacyl-ACP synthase); beta-ketoacyl synthase 2238116..2239333 Haemophilus somnus 2336 6107928 YP_001785305.1 CDS HSM_1991 NC_010519.1 2239335 2239787 D KEGG: hso:HS_0106 dehydratase; dehydratase 2239335..2239787 Haemophilus somnus 2336 6107930 YP_001785306.1 CDS fabG NC_010519.1 2239787 2240515 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 2239787..2240515 Haemophilus somnus 2336 6107931 YP_001785307.1 CDS HSM_1993 NC_010519.1 2240579 2241826 D PFAM: beta-ketoacyl synthase; KEGG: hso:HS_0108 3-oxoacyl-[acyl-carrier-protein] synthase II; beta-ketoacyl synthase 2240579..2241826 Haemophilus somnus 2336 6107932 YP_001785308.1 CDS HSM_1994 NC_010519.1 2241994 2242746 D KEGG: hso:HS_0109 hypothetical protein; hypothetical protein 2241994..2242746 Haemophilus somnus 2336 6107933 YP_001785309.1 CDS HSM_1995 NC_010519.1 2242722 2243483 D PFAM: phospholipid/glycerol acyltransferase; KEGG: hso:HS_0110 1-acyl-sn-glycerol-3-phosphate acyltransferase; phospholipid/glycerol acyltransferase 2242722..2243483 Haemophilus somnus 2336 6107934 YP_001785310.1 CDS HSM_1996 NC_010519.1 2243487 2243744 D KEGG: hso:HS_0111 acyl carrier protein; acyl carrier protein 2243487..2243744 Haemophilus somnus 2336 6107935 YP_001785311.1 CDS HSM_1997 NC_010519.1 2243760 2244008 D PFAM: phosphopantetheine-binding; KEGG: hso:HS_0112 acyl carrier protein; phosphopantetheine-binding protein 2243760..2244008 Haemophilus somnus 2336 6107936 YP_001785312.1 CDS HSM_1998 NC_010519.1 2244093 2244452 D KEGG: hso:HS_0113 3-hydroxymyristoyl/3-hydroxydecanoyl-[acyl-carrier- protein] dehydratase; (3R)-hydroxymyristoyl-ACP dehydratase 2244093..2244452 Haemophilus somnus 2336 6107937 YP_001785313.1 CDS HSM_1999 NC_010519.1 2244445 2244996 D KEGG: hso:HS_0114 hypothetical protein; hypothetical protein 2244445..2244996 Haemophilus somnus 2336 6107938 YP_001785314.1 CDS HSM_2000 NC_010519.1 2244989 2246269 D PFAM: AMP-dependent synthetase and ligase; KEGG: hso:HS_0115 conserved acyl-coenzyme A synthetase-related protein; AMP-dependent synthetase and ligase 2244989..2246269 Haemophilus somnus 2336 6107939 YP_001785315.1 CDS HSM_2001 NC_010519.1 2246266 2246994 D PFAM: glycosyl transferase family 2; KEGG: hso:HS_0116 glycosyl transferase, group 2 family protein; glycosyl transferase family protein 2246266..2246994 Haemophilus somnus 2336 6107943 YP_001785316.1 CDS HSM_2002 NC_010519.1 2246991 2247911 D PFAM: lipid A biosynthesis acyltransferase; KEGG: hso:HS_0117 acyltransferase; lipid A biosynthesis acyltransferase 2246991..2247911 Haemophilus somnus 2336 6107944 YP_001785317.1 CDS HSM_2003 NC_010519.1 2247935 2248360 D KEGG: hso:HS_0118 hypothetical protein; hypothetical protein 2247935..2248360 Haemophilus somnus 2336 6107945 YP_001785318.1 CDS HSM_2004 NC_010519.1 2248440 2248883 D KEGG: hso:HS_0119 conserved thioesterase; thioesterase 2248440..2248883 Haemophilus somnus 2336 6107946 YP_001785319.1 CDS HSM_2005 NC_010519.1 2248894 2249481 D KEGG: hso:HS_0120 hypothetical protein; hypothetical protein 2248894..2249481 Haemophilus somnus 2336 6107947 YP_001785320.1 CDS HSM_2006 NC_010519.1 2249490 2251781 D KEGG: hso:HS_0121 hypothetical protein; hypothetical protein 2249490..2251781 Haemophilus somnus 2336 6107948 YP_001785321.1 CDS HSM_2007 NC_010519.1 2251922 2253154 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(2251922..2253154) Haemophilus somnus 2336 6107949 YP_001785322.1 CDS HSM_2008 NC_010519.1 2253180 2253839 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(2253180..2253839) Haemophilus somnus 2336 6107950 YP_001785323.1 CDS HSM_2009 NC_010519.1 2253935 2255113 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(2253935..2255113) Haemophilus somnus 2336 6107951 YP_001785324.1 CDS HSM_2010 NC_010519.1 2255113 2255709 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase complement(2255113..2255709) Haemophilus somnus 2336 6107952 YP_001785325.1 CDS HSM_2011 NC_010519.1 2255899 2256234 R TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; KEGG: hso:HS_0126 ComE operon protein (competence protein); helix-hairpin-helix repeat-containing competence protein ComEA complement(2255899..2256234) Haemophilus somnus 2336 6107954 YP_001785326.1 CDS HSM_2012 NC_010519.1 2256456 2256845 R TIGRFAM: endoribonuclease L-PSP; PFAM: endoribonuclease L-PSP; KEGG: hso:HS_0127 translation initiation inhibitor (endoribonuclease L-PSP); endoribonuclease L-PSP complement(2256456..2256845) Haemophilus somnus 2336 6107955 YP_001785327.1 CDS HSM_2013 NC_010519.1 2256906 2257487 R KEGG: hso:HS_0128 hypothetical protein; hypothetical protein complement(2256906..2257487) Haemophilus somnus 2336 6107956 YP_001785328.1 CDS HSM_2014 NC_010519.1 2257636 2258643 R catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; para-aminobenzoate synthase component I complement(2257636..2258643) Haemophilus somnus 2336 6107957 YP_001785329.1 CDS HSM_2015 NC_010519.1 2258700 2259269 D catalyzes the formation of anthranilate from chorismate and glutamine; functions in tryptophan biosynthesis; anthranilate synthase component II 2258700..2259269 Haemophilus somnus 2336 6107958 YP_001785330.1 CDS HSM_2016 NC_010519.1 2259422 2259901 D PFAM: ferritin; KEGG: hso:HS_0131 DNA-binding stress protein; ferritin 2259422..2259901 Haemophilus somnus 2336 6107959 YP_001785331.1 CDS trmE NC_010519.1 2260001 2261359 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE complement(2260001..2261359) Haemophilus somnus 2336 6107960 YP_001785332.1 CDS HSM_2018 NC_010519.1 2261445 2263070 R functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC complement(2261445..2263070) Haemophilus somnus 2336 6107961 YP_001785333.1 CDS HSM_2019 NC_010519.1 2263070 2263330 R PFAM: protein of unknown function DUF37; KEGG: hso:HS_0134 hypothetical protein; hypothetical protein complement(2263070..2263330) Haemophilus somnus 2336 6107962 YP_001785334.1 CDS rnpA NC_010519.1 2263294 2263653 R protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P complement(2263294..2263653) Haemophilus somnus 2336 6107963 YP_001785335.1 CDS rpmH NC_010519.1 2263668 2263802 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(2263668..2263802) Haemophilus somnus 2336 6107965 HSM_R0001 tRNA HSM_R0001 NC_010519.1 56725 56800 R tRNA-Thr complement(56725..56800) Haemophilus somnus 2336 6108432 HSM_R0002 tRNA HSM_R0002 NC_010519.1 56804 56878 R tRNA-Gly complement(56804..56878) Haemophilus somnus 2336 6108838 HSM_R0003 tRNA HSM_R0003 NC_010519.1 56921 57005 R tRNA-Tyr complement(56921..57005) Haemophilus somnus 2336 6108839 HSM_R0004 tRNA HSM_R0004 NC_010519.1 57037 57112 R tRNA-Thr complement(57037..57112) Haemophilus somnus 2336 6108840 HSM_R0005 tRNA HSM_R0005 NC_010519.1 146001 146076 D tRNA-Lys 146001..146076 Haemophilus somnus 2336 6107234 HSM_R0006 tRNA HSM_R0006 NC_010519.1 146102 146177 D tRNA-Lys 146102..146177 Haemophilus somnus 2336 6108842 HSM_R0007 tRNA HSM_R0007 NC_010519.1 146203 146278 D tRNA-Lys 146203..146278 Haemophilus somnus 2336 6108843 HSM_R0008 tRNA HSM_R0008 NC_010519.1 210791 210880 D tRNA-Ser 210791..210880 Haemophilus somnus 2336 6107953 HSM_R0009 tRNA HSM_R0009 NC_010519.1 240492 240581 D tRNA-Ser 240492..240581 Haemophilus somnus 2336 6107986 HSM_R0010 tRNA HSM_R0010 NC_010519.1 297852 297938 R tRNA-Leu complement(297852..297938) Haemophilus somnus 2336 6108046 HSM_R0011 tRNA HSM_R0011 NC_010519.1 297963 298036 R tRNA-Cys complement(297963..298036) Haemophilus somnus 2336 6108847 HSM_R0012 tRNA HSM_R0012 NC_010519.1 298048 298123 R tRNA-Gly complement(298048..298123) Haemophilus somnus 2336 6108848 HSM_R0013 tRNA HSM_R0013 NC_010519.1 329100 329185 R tRNA-Leu complement(329100..329185) Haemophilus somnus 2336 6108079 HSM_R0015 tRNA HSM_R0015 NC_010519.1 514878 514954 D tRNA-Ile 514878..514954 Haemophilus somnus 2336 6108851 HSM_R0016 tRNA HSM_R0016 NC_010519.1 515049 515124 D tRNA-Ala 515049..515124 Haemophilus somnus 2336 6108852 HSM_R0020 tRNA HSM_R0020 NC_010519.1 631207 631283 D tRNA-Ile 631207..631283 Haemophilus somnus 2336 6108856 HSM_R0021 tRNA HSM_R0021 NC_010519.1 631378 631453 D tRNA-Ala 631378..631453 Haemophilus somnus 2336 6108857 HSM_R0025 tRNA HSM_R0025 NC_010519.1 635128 635204 D tRNA-Asp 635128..635204 Haemophilus somnus 2336 6108861 HSM_R0026 tRNA HSM_R0026 NC_010519.1 635219 635294 D tRNA-Trp 635219..635294 Haemophilus somnus 2336 6108862 HSM_R0028 tRNA HSM_R0028 NC_010519.1 673887 673962 D tRNA-Glu 673887..673962 Haemophilus somnus 2336 6108864 HSM_R0031 tRNA HSM_R0031 NC_010519.1 871177 871252 R tRNA-Ala complement(871177..871252) Haemophilus somnus 2336 6108569 HSM_R0032 tRNA HSM_R0032 NC_010519.1 872955 873030 D tRNA-Val 872955..873030 Haemophilus somnus 2336 6108570 HSM_R0033 tRNA HSM_R0033 NC_010519.1 873071 873146 D tRNA-Val 873071..873146 Haemophilus somnus 2336 6108869 HSM_R0034 tRNA HSM_R0034 NC_010519.1 873213 873288 D tRNA-Val 873213..873288 Haemophilus somnus 2336 6108870 HSM_R0035 tRNA HSM_R0035 NC_010519.1 985227 985303 D tRNA-Arg 985227..985303 Haemophilus somnus 2336 6108674 HSM_R0036 tRNA HSM_R0036 NC_010519.1 985325 985400 D tRNA-His 985325..985400 Haemophilus somnus 2336 6108872 HSM_R0037 tRNA HSM_R0037 NC_010519.1 985407 985483 D tRNA-Pro 985407..985483 Haemophilus somnus 2336 6108873 HSM_R0039 tRNA HSM_R0039 NC_010519.1 987253 987328 D tRNA-Glu 987253..987328 Haemophilus somnus 2336 6108875 HSM_R0042 tRNA HSM_R0042 NC_010519.1 990808 990884 D tRNA-Val 990808..990884 Haemophilus somnus 2336 6108878 HSM_R0043 tRNA HSM_R0043 NC_010519.1 1000829 1000905 D tRNA-Pro 1000829..1000905 Haemophilus somnus 2336 6108683 HSM_R0044 tRNA HSM_R0044 NC_010519.1 1000931 1001007 D tRNA-Arg 1000931..1001007 Haemophilus somnus 2336 6108880 HSM_R0045 tRNA HSM_R0045 NC_010519.1 1091217 1091293 R tRNA-Asp complement(1091217..1091293) Haemophilus somnus 2336 6108788 HSM_R0046 tRNA HSM_R0046 NC_010519.1 1091322 1091398 R tRNA-Asp complement(1091322..1091398) Haemophilus somnus 2336 6108882 HSM_R0047 tRNA HSM_R0047 NC_010519.1 1149488 1149563 R tRNA-Gly complement(1149488..1149563) Haemophilus somnus 2336 6106848 HSM_R0049 tRNA HSM_R0049 NC_010519.1 1295729 1295805 R tRNA-Met complement(1295729..1295805) Haemophilus somnus 2336 6106980 HSM_R0050 tRNA HSM_R0050 NC_010519.1 1301094 1301187 D tRNA-Ser 1301094..1301187 Haemophilus somnus 2336 6106982 HSM_R0051 tRNA HSM_R0051 NC_010519.1 1301198 1301274 D tRNA-Arg 1301198..1301274 Haemophilus somnus 2336 6108887 HSM_R0052 tRNA HSM_R0052 NC_010519.1 1301351 1301427 D tRNA-Arg 1301351..1301427 Haemophilus somnus 2336 6108888 HSM_R0053 tRNA HSM_R0053 NC_010519.1 1467831 1467907 D tRNA-Met 1467831..1467907 Haemophilus somnus 2336 6107154 HSM_R0054 tRNA HSM_R0054 NC_010519.1 1721509 1721583 R tRNA-Gln complement(1721509..1721583) Haemophilus somnus 2336 6107386 HSM_R0055 tRNA HSM_R0055 NC_010519.1 1721630 1721704 R tRNA-Gln complement(1721630..1721704) Haemophilus somnus 2336 6108891 HSM_R0056 tRNA HSM_R0056 NC_010519.1 1721732 1721816 R tRNA-Leu complement(1721732..1721816) Haemophilus somnus 2336 6108892 HSM_R0057 tRNA HSM_R0057 NC_010519.1 1721822 1721898 R tRNA-Met complement(1721822..1721898) Haemophilus somnus 2336 6108893 HSM_R0058 tRNA HSM_R0058 NC_010519.1 1798693 1798768 D tRNA-Asn 1798693..1798768 Haemophilus somnus 2336 6107459 HSM_R0059 tRNA HSM_R0059 NC_010519.1 1994382 1994467 R tRNA-Leu complement(1994382..1994467) Haemophilus somnus 2336 6107670 HSM_R0061 tRNA HSM_R0061 NC_010519.1 2120149 2120224 D tRNA-Glu 2120149..2120224 Haemophilus somnus 2336 6108897 HSM_R0064 tRNA HSM_R0064 NC_010519.1 2145991 2146066 D tRNA-Phe 2145991..2146066 Haemophilus somnus 2336 6107822 HSM_R0065 tRNA HSM_R0065 NC_010519.1 2146073 2146148 D tRNA-Asn 2146073..2146148 Haemophilus somnus 2336 6108901 HSM_R0014 rRNA HSM_R0014 NC_010519.1 513285 514817 D 16S ribosomal RNA 513285..514817 Haemophilus somnus 2336 6108231 HSM_R0017 rRNA HSM_R0017 NC_010519.1 515385 518372 D 23S ribosomal RNA 515385..518372 Haemophilus somnus 2336 6108853 HSM_R0018 rRNA HSM_R0018 NC_010519.1 518502 518616 D 5S ribosomal RNA 518502..518616 Haemophilus somnus 2336 6108854 HSM_R0019 rRNA HSM_R0019 NC_010519.1 629614 631146 D 16S ribosomal RNA 629614..631146 Haemophilus somnus 2336 6108346 HSM_R0022 rRNA HSM_R0022 NC_010519.1 631714 634701 D 23S ribosomal RNA 631714..634701 Haemophilus somnus 2336 6108858 HSM_R0023 rRNA HSM_R0023 NC_010519.1 634831 634945 D 5S ribosomal RNA 634831..634945 Haemophilus somnus 2336 6108859 HSM_R0024 rRNA HSM_R0024 NC_010519.1 635002 635116 D 5S ribosomal RNA 635002..635116 Haemophilus somnus 2336 6108860 HSM_R0027 rRNA HSM_R0027 NC_010519.1 672278 673810 D 16S ribosomal RNA 672278..673810 Haemophilus somnus 2336 6108375 HSM_R0029 rRNA HSM_R0029 NC_010519.1 674150 677137 D 23S ribosomal RNA 674150..677137 Haemophilus somnus 2336 6108865 HSM_R0030 rRNA HSM_R0030 NC_010519.1 677267 677381 D 5S ribosomal RNA 677267..677381 Haemophilus somnus 2336 6108866 HSM_R0038 rRNA HSM_R0038 NC_010519.1 985644 987176 D 16S ribosomal RNA 985644..987176 Haemophilus somnus 2336 6108874 HSM_R0040 rRNA HSM_R0040 NC_010519.1 987516 990503 D 23S ribosomal RNA 987516..990503 Haemophilus somnus 2336 6108876 HSM_R0041 rRNA HSM_R0041 NC_010519.1 990633 990747 D 5S ribosomal RNA 990633..990747 Haemophilus somnus 2336 6108877 HSM_R0060 rRNA HSM_R0060 NC_010519.1 2118540 2120072 D 16S ribosomal RNA 2118540..2120072 Haemophilus somnus 2336 6107796 HSM_R0062 rRNA HSM_R0062 NC_010519.1 2120412 2123399 D 23S ribosomal RNA 2120412..2123399 Haemophilus somnus 2336 6108898 HSM_R0063 rRNA HSM_R0063 NC_010519.1 2123529 2123643 D 5S ribosomal RNA 2123529..2123643 Haemophilus somnus 2336 6108899