-- dump date 20140619_112031 -- class Genbank::CDS -- table cds_note -- id note YP_663869.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_663871.1 AP endonuclease xth family; multifunctional DNA repair protein; has AP endonuclease, 3'-5' exonuclease, ribonuclease H, and 3'-phosphomonoesterase activities. YP_663874.1 catalyzes branch migration in Holliday junction intermediates YP_663875.1 (P08763) Type III restriction-modification system EcoPI enzyme mod (EC 2.1.1.72) (EcoPI methyltransferase) (M.EcoPI); hypothetical protein YP_663876.1 (P08763) Type III restriction-modification system EcoPI enzyme mod (EC 2.1.1.72) (EcoPI methyltransferase) (M.EcoPI); hypothetical protein YP_663877.1 (P08764) Type III restriction-modification system EcoPI enzyme res (EC 3.1.21.5); hypothetical protein YP_663878.1 (Q60301) Hypothetical protein MJECS02; hypothetical protein YP_663879.1 type II DNA modification enzyme (methyltransferase); hypothetical protein YP_663880.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_663881.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_663882.2 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_663883.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_663884.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_663885.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_663886.1 conserved hypothetical protein; High confidence in function and specificity YP_663887.1 membrane associated protein; High confidence in function and specificity YP_663888.1 lipopolysaccharide 1,2-glucosyltransferase (rfaJ); High confidence in function and specificity YP_663889.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_663890.1 Specificity unclear YP_663891.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_663893.1 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; High confidence in function and specificity YP_663894.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_663895.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_663896.1 conserved hypothetical protein; High confidence in function and specificity YP_663897.1 similar to jhp1463; Function unclear YP_663898.1 outer membrane protein, fragment 4; hypothetical protein YP_663899.1 outer membrane protein, fragment 3; hypothetical protein YP_663900.1 outer membrane protein, fragment 2; hypothetical protein YP_663901.1 outer membrane protein, fragment 1; hypothetical protein YP_663902.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_663903.1 (Q9ZN36) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP); High confidence in function and specificity YP_663904.1 similar to HP0028; Specificity unclear YP_663905.1 (Q9ZN34) Dethiobiotin synthetase (EC 6.3.3.3) (Dethiobiotin synthase) (DTB synthetase) (DTBS); High confidence in function and specificity YP_663906.1 Hypothetical protein similar to HP0031/JHP0027; High confidence in function and specificity YP_663907.1 similar to HP0032/JHP0028; Specificity unclear YP_663908.1 (P15716) ATP-dependent Clp protease ATP-binding subunit clpA; High confidence in function and specificity YP_663909.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_663910.1 similar to HP0035/JHP0031; High confidence in function and specificity YP_663911.1 similar to HP0036; hypothetical protein YP_663912.1 similar to JHP0033; Function unclear YP_663913.1 (Q9ZDN8) Hypothetical protein RP289; Function unclear YP_663914.1 (P17799) VirB9 protein precursor; High confidence in function and specificity YP_663915.1 (P55406) Probable conjugal transfer protein trbI; High confidence in function and specificity YP_663916.1 (P26340) Mannose-1-phosphate guanylyltransferase [GDP] (EC 2.7.7.22) (GDP-mannose pyrophosphorylase) (GMP); High confidence in function and specificity YP_663917.1 High confidence in function and specificity YP_663918.1 (P32055) GDP-L-fucose synthetase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-35-epimerase-4-reductase); High confidence in function and specificity YP_663919.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_663920.1 High confidence in function and specificity YP_663921.1 (Q9L7A6) Hypothetical lipoprotein HD0470 precursor; High confidence in function and specificity YP_663922.1 binds to flagellin and appears to stabilize flagellin during flagella assembly YP_663923.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_663924.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_663925.1 binds and unfolds substrates as part of the ClpXP protease YP_663926.1 functions in MreBCD complex in some organisms YP_663927.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_663928.1 (P32678) Protein yijP,similar to JHP1312; High confidence in function and specificity YP_663929.1 similar to JHP1312; Function unclear YP_663930.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_663931.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_663932.1 Function unclear YP_663933.1 similar to HP1511; Function unclear YP_663934.1 (P46362) Dihydroneopterin aldolase (EC 4.1.2.25) (DHNA); Function unclear YP_663935.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_663936.1 similar to HP1508; Specificity unclear YP_663937.1 (Q9P4R4) Saccharopine dehydrogenase [NADP+ L-glutamate forming] (EC 1.5.1.10) (Saccharopine reductase),similar to HP1507; Function unclear YP_663938.1 (P45240) Sodium/glutamate symport carrier protein (Glutamate permease),similar to HP1506; High confidence in function and specificity YP_663939.1 (O24750) Riboflavin biosynthesis protein ribD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) (HTP reductase)]; High confidence in function and specificity YP_663940.1 similar to HP1504; Specificity unclear YP_663941.1 (Q8Z8S4) Copper-transporting P-type ATPase (EC 3.6.3.4); High confidence in function and specificity YP_663942.1 (P42034) Hydrogenase expression/formation protein hypE; High confidence in function and specificity YP_663943.1 HypF family transcriptional regulator,similar to HP0048; High confidence in function and specificity YP_663944.1 similar to HP0049; Function unclear YP_663945.1 (O30569) Modification methylase SmeIP (EC 2.1.1.72) (Adenine-specific methyltransferase SmeIP) (M.SmeI) (M.CcrMI); hypothetical protein YP_663947.1 dpnA fragment; hypothetical protein YP_663948.1 (P34881) DNA (cytosine-5)-methyltransferase AthI (EC 2.1.1.37) (DNA methyltransferase AthI) (DNA Metase AthI) (M.AthI); hypothetical protein YP_663949.1 (P05302) Modification methylase DdeI (EC 2.1.1.37) (Cytosine-specific methyltransferase DdeI) (M.DdeI); hypothetical protein YP_663950.1 (P50192) Modification methylase HphIA (EC 2.1.1.37) (Cytosine-specific methyltransferase HphIA) (M.HphIA) (M.Hphi(C)); hypothetical protein YP_663951.1 (P94147) Modification methylase AgeI (EC 2.1.1.37) (Cytosine-specific methyltransferase AgeI) (M.AgeI); hypothetical protein YP_663952.1 Region start changed from 88584 to 88497 (87 bases) YP_663953.1 Function unclear YP_663954.1 similar to HP1284; High confidence in function and specificity YP_663955.1 similar to HP1285; Specificity unclear YP_663956.1 similar to HP1286; High confidence in function and specificity YP_663958.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_663959.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_663960.1 involved in type III protein export during flagellum assembly YP_663961.1 Function unclear YP_663962.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_663963.1 Hypothetical protein similar to HP1423/JHP1318; High confidence in function and specificity YP_663964.1 similar to HP1424; hypothetical protein YP_663966.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_663967.1 Hypothetical protein similar to HP1430; Specificity unclear YP_663968.1 Hypothetical protein similar to HP1429; High confidence in function and specificity YP_663969.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_663971.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_663972.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_663973.1 similar to HP1242; Function unclear YP_663974.1 (P14532) Cytochrome c551 peroxidase precursor (EC 1.11.1.5) (Cytochrome c peroxidase) (CCP); High confidence in function and specificity YP_663975.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_663976.1 (P55986) Hypothetical pseudouridine synthase HP1459 (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase); High confidence in function and specificity YP_663977.1 (P48384) Thioredoxin M-type chloroplast precursor (TRX-M); Function unclear YP_663982.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_663983.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_663985.1 similar to HP1321; Specificity unclear YP_663986.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_663987.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_663988.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_663989.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_663990.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_663991.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_663992.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_663993.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_663994.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_663995.1 one of the stabilizing components for the large ribosomal subunit YP_663996.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_663997.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_663998.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_663999.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_664000.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_664001.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_664002.1 binds 5S rRNA along with protein L5 and L25 YP_664003.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_664004.1 late assembly protein YP_664005.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_664006.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_664007.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_664008.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_664009.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_664010.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_664011.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_664012.1 is a component of the macrolide binding site in the peptidyl transferase center YP_664013.1 similar to HP0018; Function unclear YP_664014.1 similar to HP1457; Function unclear YP_664015.1 (P53436) LPP20 lipoprotein precursor,similar to HP1456; High confidence in function and specificity YP_664016.1 similar to HP1455; hypothetical protein YP_664017.1 similar to HP1454; hypothetical protein YP_664018.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_664019.1 similar to HP1451; hypothetical protein YP_664020.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_664021.1 similar to HP1449; High confidence in function and specificity YP_664022.1 (Q9ZJH0) Ribonuclease P protein component (EC 3.1.26.5) (RNaseP protein) (RNase P protein) (Protein C5); High confidence in function and specificity YP_664023.1 (O25987) biopolymer transport exbD-like protein; High confidence in function and specificity YP_664024.1 (Q9ZJH1) biopolymer transport exbB-like protein; High confidence in function and specificity YP_664025.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_664026.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis YP_664027.1 affects carbohydrate metabolism, has regulatory role in many processes YP_664028.1 (Q9ZJH5) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase); High confidence in function and specificity YP_664034.1 fragmented gene homologous to HP1371; hypothetical protein YP_664036.1 (Q58392) Modification methylase MjaI (EC 2.1.1.113) (N-4 cytosine-specific methyltransferase MjaI) (M.MjaI); High confidence in function and specificity YP_664037.1 (P23192) Modification methylase MboII (EC 2.1.1.72) (Adenine-specific methyltransferase MboII) (M.MboII); High confidence in function and specificity YP_664038.1 (P23192) Modification methylase MboII (EC 2.1.1.72) (Adenine-specific methyltransferase MboII) (M.MboII); High confidence in function and specificity YP_664039.1 (P23191) Type IIS restriction enzyme MboII (EC 3.1.21.4) (Endonuclease MboII) (R.MboII); High confidence in function and specificity YP_664040.1 Function unclear YP_664041.1 Specificity unclear YP_664042.1 similar to HP1363; Specificity unclear YP_664043.1 unwinds double stranded DNA YP_664044.1 (P51973) Competence protein comE3, DNA transfer protein; High confidence in function and specificity YP_664045.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_664046.1 similar to HP1359; hypothetical protein YP_664047.1 similar to HP1358; hypothetical protein YP_664048.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_664049.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_664050.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_664051.1 (Q47282) Type I restriction enzyme EcoEI M protein (EC 2.1.1.72) (M.EcoEI); hypothetical protein YP_664055.1 (Q57425) Hypothetical protein HI1077.1; High confidence in function and specificity YP_664056.1 High confidence in function and specificity YP_664057.1 Function unclear YP_664058.1 (P26276) Phosphomannomutase/phosphoglucomutase (EC 5.4.2.8) (EC 5.4.2.2) (PMM / PGM); High confidence in function and specificity YP_664059.1 flagellar functional protein; hypothetical protein YP_664060.1 Catalyzes the transfer of electrons from NADH to quinone YP_664061.1 Catalyzes the transfer of electrons from NADH to quinone YP_664062.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_664063.1 Catalyzes the transfer of electrons from NADH to quinone YP_664064.1 Catalyzes the transfer of electrons from NADH to quinone YP_664065.1 Catalyzes the transfer of electrons from NADH to quinone YP_664066.1 Catalyzes the transfer of electrons from NADH to quinone YP_664067.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_664070.1 Catalyzes the transfer of electrons from NADH to quinone YP_664071.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_664072.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_664073.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_664074.1 (O25849) NAD-dependent deacetylase (EC 3.5.1.-) (Regulatory protein SIR2 homolog); High confidence in function and specificity YP_664075.1 Function unclear YP_664076.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_664077.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_664078.1 (O25847) Protein-export membrane protein secG; High confidence in function and specificity YP_664079.1 (Q9RX93) Trans-aconitate 2-methyltransferase (EC 2.1.1.144); High confidence in function and specificity YP_664080.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_664081.1 (P33913) Hypothetical protein yejA precursor; High confidence in function and specificity YP_664082.1 (P55691) Hypothetical protein Y4WM precursor; High confidence in function and specificity YP_664083.1 (P33913) Hypothetical protein yejA precursor; High confidence in function and specificity YP_664084.1 Function unclear YP_664085.1 (P55691) Hypothetical protein Y4WM precursor; High confidence in function and specificity YP_664086.1 Function unclear YP_664087.1 Function unclear YP_664088.1 (P33914) Hypothetical ABC transporter permease yejB; High confidence in function and specificity YP_664089.1 (P33914) Hypothetical ABC transporter permease yejB; High confidence in function and specificity YP_664091.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_664092.1 (P56123) Ribonuclease R (EC 3.1.-.-) (RNase R) (VacB protein homolog); High confidence in function and specificity YP_664093.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_664094.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_664095.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_664096.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_664097.1 makes up the distal portion of the flagellar basal body rod YP_664099.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_664100.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_664101.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_664102.1 (Q9ZN54) Carbonic anhydrase (EC 4.2.1.1); High confidence in function and specificity YP_664103.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_664104.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_664105.1 High confidence in function and specificity YP_664106.1 High confidence in function and specificity YP_664107.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_664109.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_664110.1 Function unclear YP_664111.1 High confidence in function and specificity YP_664112.1 Inhibits transcription at high concentrations of nickel YP_664113.1 (Q9ZJP6) Biopolymer transport exbB protein; High confidence in function and specificity YP_664114.1 (Q9ZJP5) Biopolymer transport exbD protein; High confidence in function and specificity YP_664115.1 (O07650) TonB protein; High confidence in function and specificity YP_664116.1 High confidence in function and specificity YP_664117.1 (P27841) Magnesium and cobalt transport protein corA; High confidence in function and specificity YP_664118.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_664119.1 (O34425) Glyceraldehyde 3-phosphate dehydrogenase 2 (EC 1.2.1.59) (GAPDH) (NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase); High confidence in function and specificity YP_664120.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_664121.1 (O25903) 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) (1-AGP acyltransferase) (1-AGPAT) (Lysophosphatidic acid acyltransferase) (LPAAT); High confidence in function and specificity YP_664123.1 (Q44879) Carboxy-terminal processing protease precursor (EC 3.4.21.102) (C-terminal processing protease); High confidence in function and specificity YP_664124.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_664125.1 (P09795) Modification methylase SinI (EC 2.1.1.37) (Cytosine-specific methyltransferase SinI) (M.SinI); hypothetical protein YP_664127.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_664128.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_664129.1 (Q89AB3) Exodeoxyribonuclease V beta chain (EC 3.1.11.5); Function unclear YP_664130.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_664131.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_664132.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_664133.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_664135.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_664137.1 (P43775) Folylpolyglutamate synthase (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS); High confidence in function and specificity YP_664138.1 Function unclear YP_664139.1 High confidence in function and specificity YP_664140.1 Function unclear YP_664141.1 (O26066) Transcription-repair coupling factor (TRCF); High confidence in function and specificity YP_664142.1 (P51130) Ubiquinol-cytochrome c reductase iron-sulfur subunit (EC 1.10.2.2) (Rieske iron-sulfur protein) (RISP); Function unclear YP_664143.1 (P51131) Cytochrome b/c1 [Includes: Cytochrome b; Cytochrome c1]; High confidence in function and specificity YP_664144.1 Function unclear YP_664145.1 (P71405) Serine acetyltransferase (EC 2.3.1.30) (SAT); High confidence in function and specificity YP_664146.1 Region start changed from 259192 to 259057 (135 bases) YP_664147.1 (P24582) Modification methylase NlaIII (EC 2.1.1.72) (CATG-specific methyltransferase HpyIM) (M.HpyI); High confidence in function and specificity YP_664148.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_664149.1 protein-disulphide isomerase; Function unclear YP_664150.1 High confidence in function and specificity YP_664151.1 High confidence in function and specificity YP_664152.1 integral membrane protein; hypothetical protein YP_664153.1 High confidence in function and specificity YP_664154.1 (P44615) Serine transporter; High confidence in function and specificity YP_664155.1 (P21357) AroAII Phospho-2-dehydro-3-deoxyheptonate aldolase 1 chloroplast precursor (EC 2.5.1.54); High confidence in function and specificity YP_664157.1 (Q9ZMU4) Bacterioferritin comigratory protein homolog; High confidence in function and specificity YP_664158.1 (P77433) Hypothetical protein ykgG; Specificity unclear YP_664159.1 (P77536) electron transport protein (ykgF); High confidence in function and specificity YP_664160.1 Specificity unclear YP_664161.1 High confidence in function and specificity YP_664163.1 High confidence in function and specificity YP_664164.1 (P77405) Citrate carrier (Citrate transporter) (Citrate/succinate antiporter); High confidence in function and specificity YP_664165.1 CcoN; FixN YP_664166.1 CcoO; FixO YP_664167.1 Family membership YP_664168.1 (Q04441) Cytochrome c oxidase polypeptide II precursor (EC 1.9.3.1) (Cytochrome aa3 subunit 2) (Oxidase aa(3) subunit 2); Function unclear YP_664173.1 Function unclear YP_664174.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_664175.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_664178.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_664180.1 High confidence in function and specificity YP_664181.1 (Q9ZMS0) beta-lactamase hcpD precursor (EC 3.5.2.6) (Cysteine-rich protein D) (PBP 4) (Penicillin-binding protein 4); Specificity unclear YP_664182.1 (Q9ZMR9) Hypothetical UPF0082 protein JHP0149; High confidence in function and specificity YP_664183.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_664184.1 (Q44007) resembles Sensor proteins racS and czcS (EC 2.7.3.-); High confidence in function and specificity YP_664185.1 (P48259) Probable transcriptional regulator ycf27 (OmpR-like protein); High confidence in function and specificity YP_664188.1 (P56113) protease HP0169 precursor (EC 3.4.-.-); hypothetical protein YP_664189.1 (Q18823) Laminin-like protein C54D1.5 precursor; hypothetical protein YP_664190.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_664191.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_664194.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_664195.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_664198.1 GTPase subunit of restriction endonuclease; hypothetical protein YP_664199.1 type II restriction-modification system restriction subunit; hypothetical protein YP_664202.1 Transfers the fatty acyl group on membrane lipoproteins YP_664203.1 Uncharacterized membrane protein, required for colicin V production; hypothetical protein YP_664204.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_664205.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_664207.1 conserved hypothetical protein YP_664208.1 conserved hypothetical protein YP_664209.1 conserved hypothetical protein YP_664210.1 (O24989) Hypothetical protein HP0189(O24989) Hypothetical protein HP0189; specifity unclear YP_664211.1 (Q9ZMP2) Hypothetical protein JHP0176(Q9ZMP2); Specificity unclear YP_664212.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_664213.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_664214.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit YP_664215.1 tim; Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_664216.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_664217.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_664218.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_664219.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_664220.1 conserved hypothetical protein YP_664221.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_664222.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_664223.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_664224.1 conserved hypothetical protein YP_664227.1 (O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase); High confidence in function and specificity YP_664228.1 Region start changed from 336580 to 336529 (51 bases) YP_664230.1 (P40309) K(+)/H(+) antiporter, NA+/H+ antiporter (napA) [Helicobacter pylori 26695]; hypothetical protein YP_664232.1 (P77726) Hypothetical transport protein; hypothetical protein YP_664233.1 (Q62773) Sodium/nucleoside cotransporter 2 (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Concentrative nucleoside transporter 2) (CNT 2) (Sodium/purine nucleoside co-transporter) (SPNT) (RCNT2); hypothetical protein YP_664234.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_664235.1 (P56463) Purine nucleoside phosphorylase (EC 2.4.2.1) (Inosine phosphorylase) (PNP); High confidence in function and specificity YP_664236.1 transmembrane transport protein; Specificity unclear YP_664237.1 High confidence in function and specificity YP_664239.1 (P27676) Glutamine-binding protein precursor (GlnBP); High confidence in function and specificity YP_664240.1 glutamine transport system permease; High confidence in function and specificity YP_664241.1 glutamine transport system permease; Function unclear YP_664242.1 glutamine ABC transporter permease (glnP); Function unclear YP_664243.1 (Q9ZK47) Carbon starvation protein A homolog; High confidence in function and specificity YP_664244.1 outer membrane protein,no omp family protein; hypothetical protein YP_664245.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_664246.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_664247.1 Predicted permease; Function unclear YP_664248.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_664249.1 High confidence in function and specificity YP_664250.1 High confidence in function and specificity YP_664251.1 (Q9ZKE6) Superoxide dismutase [Fe] (EC 1.15.1.1); High confidence in function and specificity YP_664252.1 TIGR00740: methyltransferase, Specificity unclear YP_664253.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_664254.1 (O25148) Hypothetical protein HP0386/JHP0995; High confidence in function and specificity YP_664258.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_664260.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_664261.1 (Q57714) Pyruvate synthase subunit porB (EC 1.2.7.1) (Pyruvate oxidoreductase beta chain) (POR) (Pyruvic-ferredoxin oxidoreductase beta subunit); High confidence in function and specificity YP_664262.1 (O05651) Pyruvate synthase subunit porA (EC 1.2.7.1) (Pyruvate oxidoreductase alpha chain) (POR) (Pyruvic-ferredoxin oxidoreductase alpha subunit); High confidence in function and specificity YP_664263.1 (Q56316) Pyruvate synthase subunit porD (EC 1.2.7.1) (Pyruvate oxidoreductase delta chain) (POR) (Pyruvic-ferredoxin oxidoreductase delta subunit); Function unclear YP_664264.1 (Q9UYY9) Pyruvate/ketoisovalerate oxidoreductases common gamma subunit [Includes: Pyruvate synthase subunit porC (EC 1.2.7.1) (Pyruvate oxidoreductase gamma chain) (POR) (Pyruvic-ferredoxin oxidoreductase gamma subunit); Ketoisovalerate oxidor; High confidence in function and specificity YP_664267.1 (P27128) Lipopolysaccharide 13-galactosyltransferase (EC 2.4.1.44) (Lipopolysaccharide 3-alpha-galactosyltransferase); Function unclear YP_664268.1 High confidence in function and specificity YP_664269.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_664270.1 High confidence in function and specificity YP_664271.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_664272.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_664273.1 (P38448) KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) (2-keto-4-hydroxyglutarate aldolase) (KHG-aldolase); 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) (Phospho-2-dehydro-3-deoxygluconate aldolase); High confidence in function and specificity YP_664274.1 (Q9ZKB5) beta-lactamase hcpC precursor (EC 3.5.2.6) (Cysteine-rich protein C); Specificity unclear YP_664276.1 Specificity unclear YP_664277.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits YP_664278.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits YP_664279.1 (P07365) Chemotaxis protein cheW, purine-binding chemotaxis protein; Function unclear YP_664280.1 (P29072) Chemotaxis protein cheA (EC 2.7.3.-); High confidence in function and specificity YP_664281.1 (P37599) Chemotaxis protein cheV; High confidence in function and specificity YP_664282.1 (P44046) UDP-23-diacylglucosamine hydrolase (EC 3.6.1.-); High confidence in function and specificity YP_664283.1 (Q9ZKF2) Hypothetical UPF0001 protein JHP0986; Specificity unclear YP_664284.1 High confidence in function and specificity YP_664285.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_664287.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_664288.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_664289.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_664290.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_664291.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_664292.1 (P56147) Hypothetical HIT-like protein HP0404/JHP0977; High confidence in function and specificity YP_664293.1 (Q9X191) Probable cysteine desulfurase (EC 4.4.1.-or 2.8.1.7); High confidence in function and specificity YP_664296.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_664297.1 (Q48261) Neuraminyllactose-binding hemagglutinin precursor (N-acetylneuraminyllactose-binding fibrillar hemagglutinin receptor-binding subunit) (NLBH) (Flagellar sheath adhesin), neuraminyllactose-binding hemagglutinin homolog (hpaA); High confidence in function and specificity YP_664300.1 (Q10071) Probable CAAX prenyl protease 1 (EC 3.4.24.84) (Prenyl protein-specific endoprotease 1) (PPSEP 1); High confidence in function and specificity YP_664301.1 (O66506) HemK protein homolog (EC 2.1.1.-) (M.AaoHemKP); High confidence in function and specificity YP_664302.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_664303.1 Function unclear YP_664304.1 Function unclear YP_664305.1 Function unclear YP_664306.1 Function unclear YP_664307.1 (Q9LJK1) Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(13)-fucosyltransferase) (Fuc-T C3) (FucTA) (FucT1) (AtFUT11); hypothetical protein YP_664308.1 alpha (1,3)-fucosyltransferase fragment-2; hypothetical protein YP_664309.1 alpha-1,4 fucosyltransferase (fucTIII) gene; hypothetical protein YP_664310.1 (P44997) Phosphoserine phosphatase (EC 3.1.3.3) (PSP) (O-phosphoserine phosphohydrolase) (PSPase); High confidence in function and specificity YP_664311.1 High confidence in function and specificity YP_664312.1 ALPHA (1,3)-FUCOSYLTRANSFERASE [Helicobacter pylori J99]; hypothetical protein YP_664313.1 High confidence in function and specificity YP_664314.1 High confidence in function and specificity YP_664315.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_664317.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_664319.1 (P29749) Modification methylase TthHB8I (EC 2.1.1.72) (Adenine-specific methyltransferase TthHB8I) (M.TthHB8I); hypothetical protein YP_664320.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_664321.1 (Q9PKR5) Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP); High confidence in function and specificity YP_664322.1 biotin carboxylase; biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_664326.1 vacuolating cytotoxin (vacA) pseudogene; High confidence in function and specificity YP_664327.1 vacuolating cytotoxin (vacA) pseudogene; hypothetical protein YP_664328.1 vacuolating cytotoxin (vacA) pseudogene; High confidence in function and specificity YP_664329.1 vacuolating cytotoxin (vacA) pseudogene; High confidence in function and specificity YP_664330.1 vacuolating cytotoxin (vacA) pseudogene; hypothetical protein YP_664331.1 (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity YP_664332.1 vacuolating cytotoxin (vacA) pseudogene, partial sequence; High confidence in function and specificity YP_664333.1 (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity YP_664334.1 (Q9ZKW5) Vacuolating cytotoxin precursor; High confidence in function and specificity YP_664335.1 (P55981) Vacuolating cytotoxin precursor; hypothetical protein YP_664336.1 (Q48258) Vacuolating cytotoxin precursor; Conserved hypothetical protein YP_664337.1 (Q48253) Vacuolating cytotoxin precursor, vacA fragment-2; High confidence in function and specificity YP_664338.1 (Q48253) Vacuolating cytotoxin precursor,vacuolating cytotoxin (vacA) pseudogene, partial sequence; High confidence in function and specificity YP_664339.1 High confidence in function and specificity YP_664340.1 High confidence in function and specificity YP_664341.1 Specificity unclear YP_664342.1 High confidence in function and specificity YP_664343.1 (Q9ZMH1) ClpB protein; High confidence in function and specificity YP_664344.1 (P44202) Hypothetical cytochrome c-type biogenesis protein HI1454; High confidence in function and specificity YP_664345.1 High confidence in function and specificity YP_664346.1 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline YP_664348.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_664349.1 Specificity unclear YP_664353.1 (Q9ZMG1) similar to Hypothetical protein JHP0259; Specificity unclear YP_664354.1 Function unclear YP_664355.1 (Q9PI11) Indole-3-glycerol phosphate synthase (EC 4.1.1.48) (IGPS); High confidence in function and specificity YP_664356.1 High confidence in function and specificity YP_664357.1 (P25552) Guanosine-5-triphosphate3-diphosphate pyrophosphatase (EC 3.6.1.40) (Guanosine pentaphosphate phosphohydrolase) (pppGpp-5-phosphohydrolase); High confidence in function and specificity YP_664358.1 (P37692) ADP-heptose--LPS heptosyltransferase II (EC 2.4.1.-); High confidence in function and specificity YP_664359.1 acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; essential for survival; plays a role in cell responses to environmental changes YP_664360.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_664361.1 (Q91AV2) Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Includes: Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains: p9; p87; p195 (EC 3.4.24.-) (Papain-like proteinases 1/2) (PL1-PRO/PL2-PRO); Peptide HD2; Unknown protein 1; 3C-like; Function unclear YP_664362.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_664363.1 (Q58111) similar to Hypothetical UPF0003 protein MJ0700; Specificity unclear YP_664364.1 (Q9ZMF0) similar to Hypothetical protein JHP0270; Specificity unclear YP_664365.1 (Q9TJ83) Cell division protein ftsH homolog (EC 3.4.24.-) (FtsHCP); High confidence in function and specificity YP_664368.1 (Q48253) Vacuolating cytotoxin precursor; Specificity unclear YP_664369.1 (Q9ZME5) Diaminopimelate decarboxylase (EC 4.1.1.20) (DAP decarboxylase); High confidence in function and specificity YP_664370.1 (P43902) T-protein [Includes: Chorismate mutase (EC 5.4.99.5) (CM); Prephenate dehydrogenase (EC 1.3.1.12) (PDH)]; High confidence in function and specificity YP_664371.1 (P33275) Hypothetical protein MYCGA3080; Specificity unclear YP_664372.1 (P05041) Para-aminobenzoate synthase component I (EC 6.3.5.8) (ADC synthase)[EC:6.3.5.8 4.1.3.38]; High confidence in function and specificity YP_664373.1 aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates YP_664374.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook YP_664375.1 High confidence in function and specificity YP_664376.1 involved in the peptidyltransferase reaction during translation YP_664377.1 High confidence in function and specificity YP_664378.1 (P37316) Dipeptide transport system permease dppB; High confidence in function and specificity YP_664379.1 (P94312) Dipeptide transport system permease dppC; High confidence in function and specificity YP_664380.1 (P42064) Oligopeptide transport ATP-binding protein appD; High confidence in function and specificity YP_664381.1 (P37313) Dipeptide transport ATP-binding protein dppF; High confidence in function and specificity YP_664382.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_664383.1 Similar to H. pylori predicted coding region HP0304; hypothetical protein YP_664385.1 outer membrane protein, similar to Hop family; High confidence in function and specificity YP_664386.1 similar to HP1143; Function unclear YP_664387.1 Function unclear YP_664388.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_664389.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_664390.1 High confidence in function and specificity YP_664391.1 High confidence in function and specificity YP_664392.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel. YP_664393.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_664394.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_664395.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_664396.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_664397.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_664398.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_664399.1 (O25755) biopolymer transport exbB-like protein; High confidence in function and specificity YP_664400.1 (Q9ZK84) biopolymer transport exbD-like protein; High confidence in function and specificity YP_664401.1 similar to hypothetical protein jhp1056 -Helicobacter pylori (strain J99); High confidence in function and specificity YP_664402.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_664403.1 (P43036) Peptidoglycan-associated lipoprotein precursor, OmpA family, palA, excC; Function unclear YP_664405.1 (Q9ZK89) FKBP-type peptidyl-prolyl cis-trans isomerase slyD (EC 5.2.1.8) (PPIase) (Rotamase); High confidence in function and specificity YP_664408.1 (P34877) Modification methylase ScrFIA (EC 2.1.1.37) (Cytosine-specific methyltransferase ScrFIA) (M.ScrFIA) (M.ScrFI-A); High confidence in function and specificity YP_664410.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_664411.1 (P36267) Gamma-glutamyltranspeptidase precursor (EC 2.3.2.2); High confidence in function and specificity YP_664412.1 Function unclear YP_664413.1 similar to HP0415; High confidence in function and specificity YP_664414.1 High confidence in function and specificity YP_664415.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_664417.1 High confidence in function and specificity YP_664418.1 High confidence in function and specificity YP_664419.1 polysaccharide biosynthesis protein; Function unclear YP_664420.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_664423.1 fragment; hypothetical protein YP_664425.1 Function unclear YP_664432.1 High confidence in function and specificity YP_664433.1 fragment; Function unclear YP_664434.1 Region start changed from 550041 to 549678 (363 bases) YP_664438.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_664439.1 (Q9ZKM3) Cell division protein ftsA; High confidence in function and specificity YP_664440.1 Function unclear YP_664441.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_664442.1 Catalyzes the phosphorylation of UMP to UDP YP_664443.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_664444.1 High confidence in function and specificity YP_664445.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_664446.1 Specificity unclear YP_664447.1 (Q9RMZ0) Hypothetical cell-wall amidase pXO2-42 precursor (EC 3.5.1.28); High confidence in function and specificity YP_664449.1 Function unclear YP_664450.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_664451.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_664455.1 fragment; hypothetical protein YP_664457.1 fragment; hypothetical protein YP_664458.1 (Q9ZL80) Cell division protein ftsY homolog; High confidence in function and specificity YP_664460.1 High confidence in function and specificity YP_664461.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP YP_664462.1 (Q9WZS2) Probable multidrug resistance protein norM (Na(+)/drug antiporter) (Multidrug-efflux transporter); High confidence in function and specificity YP_664463.1 (P46231) Hypothetical protein VP2115 (ORF3); Specificity unclear YP_664464.1 Specificity unclear YP_664466.1 High confidence in function and specificity YP_664468.1 flagellin specific chaperone YP_664469.1 involved in flagellin assembly YP_664470.1 possibly involved in flagella export YP_664471.1 Function unclear YP_664472.1 (P95357) Cell division protein ftsX homolog; High confidence in function and specificity YP_664473.1 ftsE; cell division protein; High confidence in function and specificity YP_664474.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_664475.1 FIBRONECTIN DOMAIN-CONTAINING LIPOPROTEIN; Function unclear YP_664476.1 High confidence in function and specificity YP_664477.1 fragment; Function unclear YP_664478.1 fragment; hypothetical protein YP_664479.1 (Q9ZLA0) Rod shape-determining protein rodA; High confidence in function and specificity YP_664480.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_664481.1 (Q58276) Hypothetical HIT-like protein MJ0866; Specificity unclear YP_664482.1 (Q8DVE3) UDP-N-acetylmuramoylalanine--D-glutamate ligase (EC 6.3.2.9) (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase) (D-glutamic acid adding enzyme); High confidence in function and specificity YP_664483.1 Function unclear YP_664484.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_664485.1 (P18200) Phosphatidylglycerophosphatase A (EC 3.1.3.27); Function unclear YP_664486.1 (Q9ZLA7) aminotransferase JHP0673 (EC 2.6.1.-); High confidence in function and specificity YP_664487.1 High confidence in function and specificity YP_664488.1 conserved hypothetical protein; High confidence in function and specificity YP_664489.1 similar to HP0733 and jhp0670; hypothetical protein YP_664490.1 similar to HP0733 and jhp0669; hypothetical protein YP_664491.1 similar to HP0733 and jhp0669; hypothetical protein YP_664492.1 similar to HP0732 and jhp0669; hypothetical protein YP_664493.1 fragment; hypothetical protein YP_664494.1 fragment; hypothetical protein YP_664495.1 fragment; hypothetical protein YP_664496.1 fragment; hypothetical protein YP_664499.1 Function unclear YP_664500.1 (Q9ZKT0) Glyceraldehyde 3-phosphate dehydrogenase (EC 1.2.1.12) (GAPDH); High confidence in function and specificity YP_664501.1 (Q9ZKT1) Hypothetical protein JHP0854; Specificity unclear YP_664502.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_664504.1 Function unclear YP_664506.1 High confidence in function and specificity YP_664508.1 outer membrane protein; hypothetical protein YP_664511.1 (P08763) Type III restriction-modification system EcoPI enzyme mod (EC 2.1.1.72) (EcoPI methyltransferase) (M.EcoPI); High confidence in function and specificity YP_664512.1 (P12364) Type III restriction-modification system EcoP15I enzyme mod (EC 2.1.1.72) (EcoP15I methyltransferase) (M.EcoP15I); High confidence in function and specificity YP_664516.1 Function unclear YP_664517.1 Function unclear YP_664518.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_664519.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_664521.1 (O32243) Glycine betaine/carnitine/choline-binding protein precursor (Osmoprotectant-binding protein); High confidence in function and specificity YP_664522.1 glycine betaine/choline/proline transport system ATP-binding protein,proV; glycine betaine/choline/proline transport system ATP-binding protein; High confidence in function and specificity YP_664524.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_664525.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_664526.1 similar to HP0823; Specificity unclear YP_664527.1 (P56430) Thioredoxin (TRX); High confidence in function and specificity YP_664528.1 (P56431) Thioredoxin reductase (EC 1.8.1.9) (TRXR); High confidence in function and specificity YP_664529.1 similar to HP0629; Function unclear YP_664530.1 similar to HP0629; Function unclear YP_664531.1 Specificity unclear YP_664532.1 (P41396) 2345-tetrahydropyridine-26-dicarboxylate N-succinyltransferase (EC 2.3.1.117) (Tetrahydrodipicolinate N-succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase); Function unclear YP_664533.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_664534.1 (O87320) aminotransferase aatC (EC 2.6.1.-); High confidence in function and specificity YP_664535.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_664537.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange YP_664538.1 (Q57394) Lipooligosaccharide biosynthesis protein lic2B; Function unclear YP_664539.1 (P40717) Modulator of drug activity B; High confidence in function and specificity YP_664540.1 High confidence in function and specificity YP_664541.1 High confidence in function and specificity YP_664542.1 (P31875) Quinone-reactive Ni/Fe-hydrogenase B-type cytochrome subunit,hyaC, hydC; High confidence in function and specificity YP_664543.1 High confidence in function and specificity YP_664544.1 hydE protein; High confidence in function and specificity YP_664548.1 outer membrane protein fragment; hypothetical protein YP_664549.1 IS606-like IS element; Specificity unclear YP_664550.1 IS605-like IS element; hypothetical protein YP_664551.1 IS606-like IS element; High confidence in function and specificity YP_664552.1 plasmid encoded: H. pylori HPM8, pHPM8;,2. H. pylori P8, pHel4; hypothetical protein YP_664553.1 based on nucleotide blast, part of coding sequence ISHp608 orfB,ISHp608-like IS element; hypothetical protein YP_664554.1 ISHp608-like IS element; hypothetical protein YP_664555.1 ISHp608-like IS element; hypothetical protein YP_664556.1 ISHp608-like IS element; hypothetical protein YP_664557.1 hypothetical protein; High confidence in function and specificity YP_664559.1 (P77756) Hypothetical protein; High confidence in function and specificity YP_664560.1 (Q9UTQ0) Probable tRNA nucleotidyltransferase (EC 2.7.7.19, EC 2.7.7.25) (tRNA adenylyltransferase) (tRNA CCA-pyrophosphorylase) (CCA-adding enzyme)papS,pcnB; High confidence in function and specificity YP_664561.1 High confidence in function and specificity YP_664563.1 Specificity unclear YP_664567.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_664568.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_664569.1 carries the fatty acid chain in fatty acid biosynthesis YP_664570.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_664571.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_664574.1 similar to HP0565; High confidence in function and specificity YP_664575.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_664576.1 inner membrane protein; High confidence in function and specificity YP_664577.1 (P75939) Flagellar basal-body rod protein flgG (Distal rod protein); Function unclear YP_664578.1 (P17448) Alpha-ketoglutarate permease; High confidence in function and specificity YP_664579.1 (P44764) 23-cyclic-nucleotide 2-phosphodiesterase precursor (EC 3.1.4.16); High confidence in function and specificity YP_664580.1 ftsK; cell division protein; High confidence in function and specificity YP_664581.1 similar to HP1089; Function unclear YP_664582.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_664583.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_664584.1 High confidence in function and specificity YP_664586.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_664589.1 Lipid A export ATP-binding/permease msbA; High confidence in function and specificity YP_664591.1 Function unclear YP_664592.1 Calcium-gated potassium channel mthK; Specificity unclear YP_664593.1 required for 70S ribosome assembly YP_664594.1 High confidence in function and specificity YP_664595.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_664596.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_664598.1 hypothetical protein; hypothetical protein YP_664599.1 hypothetical protein; hypothetical protein YP_664600.1 sodium- and chloride-dependent transporter; Specificity unclear YP_664601.1 sodium-dependent transporter; Specificity unclear YP_664602.1 sodium- and chloride-dependent transporter; Specificity unclear YP_664603.1 High confidence in function and specificity YP_664604.1 binds the polymerase to DNA and acts as a sliding clamp YP_664605.1 negatively supercoils closed circular double-stranded DNA YP_664611.1 methylase yhhF (EC 2.1.1.-); Specificity unclear YP_664612.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_664613.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_664614.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_664615.1 Chemotaxis protein cheV; High confidence in function and specificity YP_664616.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_664617.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_664618.1 glycosyltransferase involved in LPS biosynthesis; High confidence in function and specificity YP_664619.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_664621.1 Specificity unclear YP_664622.1 High confidence in function and specificity YP_664623.1 Specificity unclear YP_664624.1 High confidence in function and specificity YP_664625.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_664626.1 Function unclear YP_664628.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_664629.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_664630.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_664631.1 High confidence in function and specificity YP_664632.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_664633.1 High confidence in function and specificity YP_664634.1 NAD-dependent deacetylase (EC 3.5.1.-) (Regulatory protein SIR2 homolog); High confidence in function and specificity YP_664637.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_664639.1 High confidence in function and specificity YP_664640.1 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase); High confidence in function and specificity YP_664641.1 conserved hypothetical integral membrane protein, permease; Function unclear YP_664642.1 oxido-reductase; High confidence in function and specificity YP_664643.1 Catalyzes the rate-limiting step in dNTP synthesis YP_664644.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_664645.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_664646.1 Iron(III) dicitrate transport protein fecA; High confidence in function and specificity YP_664647.1 Ferrous iron transport protein B homolog; High confidence in function and specificity YP_664648.1 Specificity unclear YP_664651.1 Region start changed from 762342 to 762384 (42 bases) YP_664653.1 Function unclear YP_664654.1 High confidence in function and specificity YP_664655.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_664656.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_664657.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_664658.1 Function unclear YP_664659.1 Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase); High confidence in function and specificity YP_664660.1 Region start changed from 770282 to 770210 (72 bases) YP_664661.1 Function unclear YP_664662.1 High confidence in function and specificity YP_664663.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_664664.1 heat shock protein involved in degradation of misfolded proteins YP_664665.1 heat shock protein involved in degradation of misfolded proteins YP_664666.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_664667.1 Function unclear YP_664674.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_664675.1 Glycolate oxidase subunit glcD; High confidence in function and specificity YP_664677.1 uridine diphosphate glucose pyrophosphatase (EC 3.6.1.45) (UGPPase) (Nucleoside diphosphate linked moiety X motif 14); High confidence in function and specificity YP_664678.1 Specificity unclear YP_664679.1 periplasmic protein; hypothetical protein YP_664682.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_664683.2 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_664684.1 High confidence in function and specificity YP_664686.1 type I restriction enzyme specificity protein; Function unclear YP_664689.1 Cadmium zinc and cobalt transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); High confidence in function and specificity YP_664690.1 Specificity unclear YP_664691.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_664692.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_664693.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_664695.1 High confidence in function and specificity YP_664696.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_664700.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate YP_664701.1 Function unclear YP_664702.1 Function unclear YP_664703.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_664705.1 High confidence in function and specificity YP_664707.1 High confidence in function and specificity YP_664708.1 Function unclear YP_664710.1 High confidence in function and specificity YP_664712.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_664713.1 High confidence in function and specificity YP_664714.1 Function unclear YP_664715.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_664721.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_664722.1 Probable L-asparaginase (EC 3.5.1.1) (L-asparagine amidohydrolase) (L-ASNase); High confidence in function and specificity YP_664723.1 acetone carboxylase gamma subunit; Function unclear YP_664724.1 High confidence in function and specificity YP_664725.1 Hydantoin utilization protein A (ORF2); High confidence in function and specificity YP_664726.1 Function unclear YP_664727.1 Short-chain fatty acids transporter; High confidence in function and specificity YP_664728.1 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5) (Succinyl CoA:3-oxoacid CoA-transferase) (OXCT B); High confidence in function and specificity YP_664729.1 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) (Succinyl CoA:3-oxoacid CoA-transferase) (OXCT A); High confidence in function and specificity YP_664730.1 Acetyl-CoA acetyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase); High confidence in function and specificity YP_664732.1 Diacylglycerol kinase (EC 2.7.1.107) (DAGK) (Diglyceride kinase) (DGK); High confidence in function and specificity YP_664733.1 negatively supercoils closed circular double-stranded DNA YP_664735.1 High confidence in function and specificity YP_664737.1 High confidence in function and specificity YP_664738.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_664739.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_664740.1 binds to and inhibits the function of flagella specific ATPase FliI YP_664741.1 One of three proteins involved in switching the direction of the flagellar rotation YP_664742.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_664743.1 Function unclear YP_664744.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_664745.1 Single-stranded-DNA-specific exonuclease recJ (EC 3.1.-.-); High confidence in function and specificity YP_664746.1 Hypothetical pseudouridine synthase JHP0321 (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase); High confidence in function and specificity YP_664747.1 Region start changed from 859755 to 860022 (267 bases) YP_664749.1 Function unclear YP_664750.1 Function unclear YP_664753.1 Function unclear YP_664754.1 beta-lactamase hcpC precursor (EC 3.5.2.6) (Cysteine-rich protein C); Specificity unclear YP_664755.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_664756.1 High confidence in function and specificity YP_664757.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_664758.1 Septum site-determining protein minD (Cell division inhibitor minD); High confidence in function and specificity YP_664759.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_664760.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_664761.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_664762.1 Function unclear YP_664763.1 neuA; CMP-N-acetylneuraminic acid synthetase [EC:2.7.7.43]; High confidence in function and specificity YP_664764.1 Acylneuraminate cytidylyltransferase (EC 2.7.7.43) (CMP-N-acetylneuraminic acid synthetase) (CMP-NeuNAc synthetase) (CMP-sialic acid synthetase); High confidence in function and specificity YP_664765.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_664767.1 membrane-associated cation-independent thermostable nuclease; preferentially cleaves ss-DNA; involved in DNA transformation YP_664769.1 Essential for recycling GMP and indirectly, cGMP YP_664770.1 Sec-independent protein translocase protein tatA/E homolog; High confidence in function and specificity YP_664771.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_664772.1 Specificity unclear YP_664775.1 nitrite extrusion protein (narK); Function unclear YP_664776.1 nitrite extrusion protein (narK); Function unclear YP_664777.1 cobalamin synthesis protein/P47K family protein; Specificity unclear YP_664779.1 High confidence in function and specificity YP_664780.1 High confidence in function and specificity YP_664781.1 High confidence in function and specificity YP_664782.1 High confidence in function and specificity YP_664785.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_664788.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_664789.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_664791.1 High confidence in function and specificity YP_664793.1 NAD(P)H nitroreductase (EC 1.-.-.-); High confidence in function and specificity YP_664794.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_664795.1 High confidence in function and specificity YP_664796.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_664797.1 Specificity unclear YP_664798.1 High confidence in function and specificity YP_664799.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_664800.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_664801.1 Function unclear YP_664802.1 Function unclear YP_664803.1 Function unclear YP_664807.1 Function unclear YP_664808.1 Function unclear YP_664810.1 Specificity unclear YP_664811.1 Function unclear YP_664813.1 Function unclear YP_664815.1 (O25620) Virulence-associated protein D homolog; High confidence in function and specificity YP_664817.1 (P94177) Cation efflux system protein czcA; High confidence in function and specificity YP_664818.1 (Q44585) Nickel-cobalt-cadmium resistance protein nccB; Function unclear YP_664820.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_664821.1 High confidence in function and specificity YP_664822.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_664823.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_664824.1 High confidence in function and specificity YP_664825.1 (P44997) Phosphoserine phosphatase (EC 3.1.3.3) (PSP) (O-phosphoserine phosphohydrolase) (PSPase); High confidence in function and specificity YP_664827.1 (P32849) DNA repair protein RAD5; Function unclear YP_664828.1 catalyzes the formation of fumarate from aspartate YP_664829.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_664831.1 (Q9I291) UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (Alpha-D-glucosyl-1-phosphate uridylyltransferase) (Uridine diphosphoglucose pyrophosphorylase); High confidence in function and specificity YP_664832.1 High confidence in function and specificity YP_664833.1 Function unclear YP_664834.1 charges one glutamine molecule and pairs it with tRNA(Gln) YP_664836.1 Function unclear YP_664837.1 (O25225) GTP-binding protein TypA/BipA homolog; High confidence in function and specificity YP_664838.1 (P29347) Modification methylase StsI (EC 2.1.1.72) (Adenine-specific methyltransferase StsI) (M.StsI); High confidence in function and specificity YP_664839.1 High confidence in function and specificity YP_664840.1 (Q9ZKR8) Hypothetical protein JHP0867; High confidence in function and specificity YP_664842.1 formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate YP_664844.1 High confidence in function and specificity YP_664845.1 Specificity unclear YP_664846.1 (Q9ZKR8) Hypothetical protein JHP0867; High confidence in function and specificity YP_664848.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_664849.1 (P34802) Geranylgeranyl pyrophosphate synthetase chloroplast precursor (GGPP synthetase) (GGPS) [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)]; High confidence in function and specificity YP_664850.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_664851.1 metalloprotease YP_664852.1 catalyzes the modification of U13 in tRNA(Glu) YP_664853.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_664854.1 (Q9ZKS7) Probable tautomerase JHP0858 (EC 5.3.2.-); hypothetical protein YP_664856.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_664860.1 (Q8XA20) Glutathione-regulated potassium-efflux system protein kefC (K(+)/H(+) antiporter); High confidence in function and specificity YP_664861.1 (P94876) Oligoendopeptidase F chromosomal (EC 3.4.24.-); High confidence in function and specificity YP_664867.1 Function unclear YP_664868.1 ); Function unclear YP_664869.1 Function unclear YP_664870.1 (Q60295) type I restriction enzyme MjaXP R protein (EC 3.1.21.3); Function unclear YP_664871.1 High confidence in function and specificity YP_664872.1 (Q47163) Type I restriction enzyme EcoprrI M protein (EC 2.1.1.72) (M.EcoprrI); High confidence in function and specificity YP_664874.1 (Q60296) type I restriction enzyme MjaXP specificity protein (S protein) (S.MjaXP); High confidence in function and specificity YP_664875.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_664876.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_664877.1 (P55679) Hypothetical zinc protease y4wA (EC 3.4.99.-); High confidence in function and specificity YP_664878.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_664879.1 Acts on the hydroxyl group at position 7 of the steroid frame YP_664881.1 (P46322) CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase) (PGP synthase); Function unclear YP_664882.1 (Q47689) Probable S-methylmethionine permease; High confidence in function and specificity YP_664883.1 High confidence in function and specificity YP_664884.1 bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations YP_664885.1 (P45337) Transcriptional regulatory protein qseB; Specificity unclear YP_664886.1 (Q9KAV6) Probable 5-3 exonuclease (EC 3.1.11.-); Function unclear YP_664888.1 High confidence in function and specificity YP_664889.1 (P45277) HTH-type transcriptional regulator zntR homolog; High confidence in function and specificity YP_664890.1 (Q9WYX8) Hypothetical protein TM0508; Specificity unclear YP_664891.1 (Q9ZM26) Ferric uptake regulation protein (Ferric uptake regulator); High confidence in function and specificity YP_664892.1 Function unclear YP_664893.1 (P37673) Hypothetical protein yiaL; Function unclear YP_664894.1 One of three proteins involved in switching the direction of the flagellar rotation YP_664895.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_664896.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_664898.1 flagellar biosynthesis switch protein; High confidence in function and specificity YP_664899.1 positive regulator of class III flagellar genes YP_664900.1 (O25680) 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) (78-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-78-dihydropterin pyrophosphokinase) (PPPK); High confidence in function and specificity YP_664901.1 (P54518) peptidase yqhT (EC 3.4.-.-); High confidence in function and specificity YP_664902.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_664903.1 (P27243) O-antigen ligase; Function unclear YP_664904.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_664905.1 membrane protein involved in the flagellar export apparatus YP_664906.1 Function unclear YP_664911.1 outer membrane protein region, nucleotide level blastn; hypothetical protein YP_664912.1 (P77380) Transcriptional regulatory protein cusR; High confidence in function and specificity YP_664913.1 (O25685) Hypothetical protein HP1044; High confidence in function and specificity YP_664914.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_664915.1 (Q9ZM44) Hypothetical UPF0090 protein JHP0379; Specificity unclear YP_664916.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_664917.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_664918.1 (O66647) Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS); Function unclear YP_664919.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_664920.1 (Q8RF47) Bifunctional 3-dehydroquinate synthase/phosphatase [Includes: 3-dehydroquinate synthase (EC 4.2.3.4); Unknown phosphatase (EC 3.6.1.-)]; Function unclear YP_664921.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_664922.1 blocks the formation of polar Z-ring septums YP_664923.1 Function unclear YP_664924.1 (O67300) Hypothetical protein AQ_1259 precursor; hypothetical protein YP_664927.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_664928.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_664929.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_664930.1 (O25701) Sec-independent protein translocase protein tatC homolog; High confidence in function and specificity YP_664931.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_664932.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_664936.1 (P71129) Chemotaxis protein cheY homolog; High confidence in function and specificity YP_664937.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_664938.1 (Q9ZM66) Cell division protein ftsH homolog (EC 3.4.24.-); High confidence in function and specificity YP_664939.1 (Q9ZM68) CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) (Phosphatidylserine synthase); High confidence in function and specificity YP_664940.1 (Q59467) Copper-transporting ATPase (EC 3.6.3.4); High confidence in function and specificity YP_664941.1 (Q9ZM70) COP associated protein (Copper ion binding protein); High confidence in function and specificity YP_664947.1 Region start changed from 1031643 to 1031688 (45 bases) YP_664950.1 HP0827: ss-DNA binding protein 12RNP2 precursor; High confidence in function and specificity YP_664951.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_664952.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_664953.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_664955.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_664956.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_664958.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_664959.1 (Q92SJ7) Integration host factor beta-subunit (IHF-beta); High confidence in function and specificity YP_664960.1 Function unclear YP_664962.1 (P59741) Long-chain fatty acid transport protein precursor (Outer membrane fadL protein) (Outer membrane flp protein); Function unclear YP_664963.1 (Q58461) Hypothetical protein MJ1061; High confidence in function and specificity YP_664964.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_664966.1 (P08455) Modification methylase NgoPII (EC 2.1.1.37) (Cytosine-specific methyltransferase NgoPII) (M.NgoPII); High confidence in function and specificity YP_664967.1 (O68584) Type II restriction enzyme HaeIII (EC 3.1.21.4) (Endonuclease HaeIII) (R.HaeIII); Specificity unclear YP_664968.1 (P75806) Hypothetical protein ybjG; Specificity unclear YP_664969.1 related to restriction endonuclease-replacing gene A; Function unclear YP_664970.1 High confidence in function and specificity YP_664971.1 (Q51392) Probable poly(beta-D-mannuronate) O-acetylase (EC 2.3.1.-) (Alginate biosynthesis protein algI); High confidence in function and specificity YP_664973.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_664974.1 High confidence in function and specificity YP_664975.1 (P45048) ADP-L-glycero-D-manno-heptose-6-epimerase (EC 5.1.3.20) (ADP-glyceromanno-heptose 6-epimerase); High confidence in function and specificity YP_664976.1 High confidence in function and specificity YP_664977.1 Specificity unclear YP_664978.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_664979.1 (Q83BS1) Translation initiation factor IF-2; High confidence in function and specificity YP_664981.1 catalyzes the formation of dUMP from dUTP YP_664982.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_664983.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_664984.1 Specificity unclear YP_664985.1 plays a role in hydrogenase nickel cofactor insertion YP_664986.1 the hook connects flagellar basal body to the flagellar filament YP_664987.1 (P06282) CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) (CDP-diacylglycerol phosphatidylhydrolase) (CDP-diglyceride hydrolase); High confidence in function and specificity YP_664988.1 (P16680) PhnA protein; Function unclear YP_664991.1 (P77872) Catalase (EC 1.11.1.6); High confidence in function and specificity YP_664992.1 (P44523) Heme/hemopexin utilization protein C precursor; Function unclear YP_664993.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_664994.1 Function unclear YP_664999.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_665001.1 (O25551) Virulence factor mviN homolog; High confidence in function and specificity YP_665002.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_665003.1 (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity YP_665004.1 (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity YP_665005.1 (Q48258) Vacuolating cytotoxin precursor; Conserved hypothetical protein YP_665006.1 (P55981) Vacuolating cytotoxin precursor; hypothetical protein YP_665007.1 (Q9ZKW5) Vacuolating cytotoxin precursor; High confidence in function and specificity YP_665008.1 (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity YP_665009.1 (Q48247) Vacuolating cytotoxin precursor; High confidence in function and specificity YP_665010.1 (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity YP_665012.1 (Q48258) Vacuolating cytotoxin precursor, inactive; High confidence in function and specificity YP_665013.1 (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity YP_665014.1 (Q48258) Vacuolating cytotoxin precursor; hypothetical protein YP_665015.1 (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity YP_665016.1 High confidence in function and specificity YP_665017.1 Specificity unclear YP_665018.1 (Q9AFG9) Acylneuraminate cytidylyltransferase (EC 2.7.7.43) (CMP-N-acetylneuraminic acid synthetase) (CMP-NeuNAc synthetase) (CMP-sialic acid synthetase); High confidence in function and specificity YP_665019.1 High confidence in function and specificity YP_665020.1 (Q9NR45) Sialic acid synthase (N-acetylneuraminate synthase) (EC 2.5.1.56) (N-acetylneuraminic acid synthase) (N-acetylneuraminate-9-phosphate synthase) (EC 2.5.1.57) (N-acetylneuraminic acid phosphate synthase); High confidence in function and specificity YP_665021.1 (O05732) Probable iron chelatin transport ATP-binding protein HP0888; High confidence in function and specificity YP_665022.1 (O05731) Probable iron chelatin transport system permease HP0889; High confidence in function and specificity YP_665023.1 (Q9ZKW1) Probable short-chain type dehydrogenase/reductase vdlC (EC 1.-.-.-); High confidence in function and specificity YP_665024.1 (O05729) Protein vdlD; High confidence in function and specificity YP_665029.1 (P31904) Hydrogenase expression/formation protein hypD2; High confidence in function and specificity YP_665030.1 (P31900) Hydrogenase expression/formation protein hypC; Function unclear YP_665031.1 (Q9ZKU8) Hydrogenase/urease nickel incorporation protein hypB; High confidence in function and specificity YP_665032.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_665033.1 (Q9ZKU4) Phosphate acetyltransferase (EC 2.3.1.8) (Phosphotransacetylase); High confidence in function and specificity YP_665035.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod YP_665036.1 the hook connects flagellar basal body to the flagellar filament YP_665038.1 (P43423) Modification methylase BseCI (EC 2.1.1.72) (Adenine-specific methyltransferase BseCI) (M.BseCI); High confidence in function and specificity YP_665039.1 High confidence in function and specificity YP_665042.1 (P13036) Iron(III) dicitrate transport protein fecA precursor; High confidence in function and specificity YP_665043.1 Outer membrane protein ,fecA inserted, fragment; hypothetical protein YP_665044.1 ABC-type Amino-acid transport system, permease component.; High confidence in function and specificity YP_665045.1 High confidence in function and specificity YP_665046.1 Homologous to H. pylori gene product HP0947,jhp0881; hypothetical protein YP_665047.1 Conserved hypothetical protein YP_665048.1 Conserved hypothetical protein; Conserved hypothetical protein YP_665049.1 High confidence in function and specificity YP_665050.1 sodium/ alanine symporter; High confidence in function and specificity YP_665051.1 (Q9ZKQ9) Alanine racemase (EC 5.1.1.1); High confidence in function and specificity YP_665052.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_665053.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_665054.1 Essential for efficient processing of 16S rRNA YP_665055.1 Conserved hypothetical protein YP_665056.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_665057.1 (Q9ZK62) Signal recognition particle protein (Fifty-four homolog); High confidence in function and specificity YP_665058.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_665059.1 binds to flagellin and appears to stabilize flagellin during flagella assembly YP_665060.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_665061.1 Conserved hypothetical protein YP_665062.1 Conserved hypothetical protein YP_665063.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_665064.1 High confidence in function and specificity YP_665065.1 Conserved hypothetical protein YP_665066.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_665067.1 Conserved hypothetical integral membrane protein; Function unclear YP_665068.1 Probable Nitrogen fixation protein fixS; Function unclear YP_665069.1 (P52214) Thioredoxin reductase (EC 1.8.1.9) (TRXR) (TR); High confidence in function and specificity YP_665070.1 permease of Major facilitator Superfamily.; hypothetical protein YP_665071.1 Function unclear YP_665072.1 Function unclear YP_665073.1 Function unclear YP_665074.1 Conserved hypothetical protein YP_665075.1 Probable tautomerase; Conserved hypothetical protein YP_665076.1 DNA repair and recombination protein.; Conserved hypothetical protein YP_665078.1 Specificity unclear YP_665081.1 Function unclear YP_665082.1 Function unclear YP_665083.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_665085.1 (P12364) Type III restriction-modification system EcoP15I enzyme mod (EC 2.1.1.72) (EcoP15I methyltransferase) (M.EcoP15I); High confidence in function and specificity YP_665086.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_665087.1 Specificity unclear YP_665088.1 High confidence in function and specificity YP_665090.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_665094.1 ABC transporter permease; High confidence in function and specificity YP_665095.1 ABC-type peptide transport, permease component; Function unclear YP_665096.1 ABC transporter permease; Function unclear YP_665097.1 ABC-type peptide transport, permease component; Function unclear YP_665098.1 Peptide transport ATP-binding protein; High confidence in function and specificity YP_665099.1 Probable ABC-type transport system, ATPase component.; hypothetical protein YP_665100.1 (P33916) Hypothetical ABC transporter ATP-binding protein yejF; hypothetical protein YP_665101.1 (P24137) Oligopeptide transport ATP-binding protein oppF; High confidence in function and specificity YP_665103.1 Function unclear YP_665104.1 High confidence in function and specificity YP_665105.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_665106.1 Specificity unclear YP_665107.1 High confidence in function and specificity YP_665108.1 High confidence in function and specificity YP_665109.1 (Q55790) Hypothetical protein slr0074; hypothetical protein YP_665111.1 Bifunctional short chain isoprenyl diphosphate synthase [Includes: Farnesyl pyrophosphate synthetase (EC 2.5.1.1) (FPP synthetase) (Dimethylallyltransferase); Geranyltranstransferase (EC 2.5.1.10)]; High confidence in function and specificity YP_665112.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_665113.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_665114.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_665116.1 Specificity unclear YP_665123.1 ABC-type cobalt transport system, ATP-binding protein; Function unclear YP_665124.1 Conserved hypothetical protein YP_665125.1 vacuolating cytotoxin precursor; Specificity unclear YP_665127.1 AcrB/AcrD/AcrF family protein; High confidence in function and specificity YP_665128.1 Probable membrane-fusion protein; Function unclear YP_665129.1 Outer membrane protein precursor; Function unclear YP_665130.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_665132.1 High confidence in function and specificity YP_665133.1 FlaA; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions YP_665134.1 Function unclear YP_665136.1 Multidrug resistance ABC transporter ATP-binding and permease; Function unclear YP_665137.1 Function unclear YP_665138.1 High confidence in function and specificity YP_665139.1 High confidence in function and specificity YP_665140.1 Penicillin-binding protein 1A (PBP-1a) (PBP1a) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.2.-) (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC 3.4.-.-) (DD-transpeptidase)]; High confidence in function and specificity YP_665141.2 Tip-alpha; forms a dimer; found in culture supernatant; induces TNF-alpha and NF-kappa-B in cell cultures of mouse cells YP_665145.1 Type III restriction-modification system EcoPI enzyme mod (EC 2.1.1.72) (EcoPI methyltransferase) (M.EcoPI); High confidence in function and specificity YP_665146.1 High confidence in function and specificity YP_665147.1 2-oxoglutarate synthase subunit korC (EC 1.2.7.3) (2-ketoglutarate oxidoreductase gamma chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase gamma subunit); High confidence in function and specificity YP_665148.1 2-oxoglutarate synthase subunit korB (EC 1.2.7.3) (2-ketoglutarate oxidoreductase beta chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase beta subunit); High confidence in function and specificity YP_665149.1 2-oxoglutarate synthase subunit korA (EC 1.2.7.3) (2-ketoglutarate oxidoreductase alpha chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase alpha subunit); High confidence in function and specificity YP_665150.1 NADH-ubiquinone oxidoreductase 23 kDa subunit mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-23KD) (CI-23KD) (Complex I-28.5KD) (CI-28.5KD); High confidence in function and specificity YP_665151.1 High confidence in function and specificity YP_665153.1 Ferrous iron transport protein A; High confidence in function and specificity YP_665154.1 Endonuclease III (EC 4.2.99.18) (DNA-(apurinic or apyrimidinic site) lyase); High confidence in function and specificity YP_665155.1 One of three proteins involved in switching the direction of the flagellar rotation YP_665157.1 SIDEROPHORE-MEDIATED IRON TRANSPORT PROTEIN; Function unclear YP_665158.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_665159.1 Predicted neuraminidase (sialidase); Function unclear YP_665161.1 Probable phosphoglycerol transferase; Specificity unclear YP_665162.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_665163.1 Signal peptidase I (EC 3.4.21.89) (SPase I) (Leader peptidase I); High confidence in function and specificity YP_665164.1 (O67776) Hypothetical zinc metalloprotease AQ_1964 (EC 3.4.24.-); Function unclear YP_665165.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_665167.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_665168.1 Specificity unclear YP_665169.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_665170.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_665174.1 (P13036) Iron(III) dicitrate transport protein fecA precursor; High confidence in function and specificity YP_665178.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_665179.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_665180.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_665181.1 (O24940) Hypothetical protein HP0122/JHP0112 precursor; Conserved hypothetical protein YP_665182.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_665183.1 outer membrane protein; hypothetical protein YP_665184.1 Function unclear YP_665185.1 High confidence in function and specificity YP_665186.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_665187.1 catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine YP_665188.1 (Q9ZMW6) Cysteine synthase; High confidence in function and specificity YP_665190.1 Probable proton transporting ATP synthase subunit,atp I; hypothetical protein YP_665191.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_665192.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_665193.1 Acts as a negative regulator of the grpE-dnaK-dnaJ and groELS class I heat shock operons by preventing heat-shock induction YP_665194.1 ribulose-5-phosphate 4-epimerase; Function unclear YP_665196.1 Function unclear YP_665197.1 FlaB; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions YP_665198.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_665199.1 Probable Fe-S oxidoreductases; Specificity unclear YP_665200.1 Function unclear YP_665201.1 Methyl-accepting chemotaxis protein; Function unclear YP_665202.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_665204.1 Involved in the metabolism of aromatic amino acids YP_665206.1 ISHp608-like IS element; hypothetical protein YP_665207.1 ISHp608-like IS element; hypothetical protein YP_665208.1 ISHp608-like IS element; hypothetical protein YP_665209.1 N-terminal truncated, 1-22 aa missing,ISHp608-like IS element; Specificity unclear YP_665214.1 integral membrane protein; Specificity unclear YP_665215.1 (Q9ZMK8) Peptide methionine sulfoxide reductase; High confidence in function and specificity YP_665216.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_665217.1 (P23121) Nitrogen fixation protein nifU; High confidence in function and specificity YP_665218.1 (Q9ZML2) Cysteine desulfurase (EC 2.8.1.7); High confidence in function and specificity YP_665220.1 Predicted phospholipid-binding protein; High confidence in function and specificity YP_665221.1 glycosyltransferase; hypothetical protein YP_665222.1 dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase [EC:1.1.1.267]; High confidence in function and specificity YP_665223.1 dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase [EC:1.1.1.267]; High confidence in function and specificity YP_665224.1 High confidence in function and specificity YP_665225.1 (Q8WWT9) Solute carrier family 13 member 3 (Sodium-dependent high-affinity dicarboxylate transporter 2); High confidence in function and specificity YP_665226.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_665227.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_665228.1 molecular chaperone YP_665231.1 type II DNA modification enzyme (methyltransferase) [EC:2.1.1.72]; High confidence in function and specificity YP_665232.1 Conserved hypothetical protein YP_665233.1 Function unclear YP_665234.1 (P71019) Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39) (MCT); High confidence in function and specificity YP_665235.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_665236.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_665237.1 exported protein; Conserved hypothetical protein YP_665238.1 (O24913) Malate:quinone oxidoreductase (EC 1.1.99.16) (Malate dehydrogenase [acceptor]) (MQO); High confidence in function and specificity YP_665239.1 (O24912) Hypothetical protein HP0085/JHP0078; Conserved hypothetical protein YP_665240.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_665241.1 forms a direct contact with the tRNA during translation YP_665242.1 Methyl-accepting chemotaxis protein mcpB; Function unclear YP_665244.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_665245.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_665246.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_665247.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_665248.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits YP_665249.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits YP_665250.1 High confidence in function and specificity YP_665251.1 involved in the assembly of the urease metallocenter; possible nickel donor YP_665252.1 (Q09065) Urease accessory protein ureF; High confidence in function and specificity YP_665253.1 (Q9ZMZ7) Urease accessory protein ureG; High confidence in function and specificity YP_665254.1 (Q9ZMZ8) Urease accessory protein ureH; High confidence in function and specificity YP_665257.1 Conserved hypothetical protein YP_665258.1 Function unclear YP_665260.1 (P27129) Lipopolysaccharide 1,2-glucosyltransferase; High confidence in function and specificity YP_665261.1 Conserved hypothetical protein YP_665265.1 IS605 like IS element; High confidence in function and specificity YP_665266.1 tnpA, N-terminal fragment; Function unclear YP_665272.1 (O52485) Bifunctional putA protein [Includes: Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C dehydrogenase)](O52485) Bifunctional putA protein [Includes: Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C dehydrogenase)]; High confidence in function and specificity YP_665273.1 (P07117) Sodium/proline symporter (Proline permease); High confidence in function and specificity YP_665274.1 (P25148) General stress protein A(P25148) General stress protein A; High confidence in function and specificity YP_665275.1 (O24999) Mrp protein homolog(O24999) Mrp protein homolog; High confidence in function and specificity YP_665278.1 (P53127) Hypothetical 163.2 kDa protein in RPL1B-CEG1 intergenic region(P53127) Hypothetical 163.2 kDa protein in RPL1B-CEG1 intergenic region; conserved hypothetical protein YP_665279.1 (O25801) Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) (ASA dehydrogenase) (ASADH)(O25801) Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) (ASA dehydrogenase) (ASADH); High confidence in function and specificity YP_665280.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_665281.1 High confidence in function and specificity YP_665282.1 (P35612) Beta adducin (Erythrocyte adducin beta subunit)(P35612) Beta adducin (Erythrocyte adducin beta subunit); conserved hypothetical protein YP_665283.1 Function unclear YP_665284.1 (P49249) IN2-2 protein(P49249) IN2-2 protein; High confidence in function and specificity YP_665285.1 (Q09923) Aldo-keto reductase yakc [NADP+] (EC 1.1.1.-)(Q09923) Aldo-keto reductase yakc [NADP+] (EC 1.1.1.-); High confidence in function and specificity YP_665286.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_665287.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_665288.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_665289.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; fusion of rpoB and rpoC; beta and beta' subunits are part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_665290.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_665291.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_665292.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_665293.1 binds directly to 23S ribosomal RNA YP_665294.1 Modulates Rho-dependent transcription termination YP_665295.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_665296.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_665297.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_665298.1 (P22638) Heterocyst differentiation ATP-binding protein hepA(P22638) Heterocyst differentiation ATP-binding protein hepA; High confidence in function and specificity YP_665299.1 (Q8DCT7) Phosphoglycolate phosphatase (EC 3.1.3.18) (PGP)(Q8DCT7) Phosphoglycolate phosphatase (EC 3.1.3.18) (PGP); conserved hypothetical protein YP_665300.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_665301.1 (P50849) Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase) (Vegetative protein 15) (VEG15)(P50849) Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase) (Vegetative protein 15) (VEG15); High confidence in function and specificity YP_665302.1 conserved hypothetical protein YP_665303.1 (Q8PP22) Organic solvent tolerance protein precursor(; Function unclear YP_665304.1 Function unclear YP_665305.1 High confidence in function and specificity YP_665306.1 (P54591) Hypothetical ABC transporter ATP-binding protein yhcG(P54591) Hypothetical ABC transporter ATP-binding protein yhcG; High confidence in function and specificity YP_665307.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_665308.1 (Q57252) Protein HI1163(Q57252) Protein HI1163; High confidence in function and specificity YP_665309.1 Function unclear YP_665310.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_665311.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_665314.1 Function unclear YP_665317.1 weak: bacteriophage-related protein; hypothetical protein YP_665319.1 hypothetical protein CUP0976,Campylobacter upsaliensis strain RM3195,NCBI entry: 11-JAN-2005; High confidence in function and specificity YP_665320.1 DNA primase DnaG (605) [Campylobacter jejuni RM1221, note: N-terminal fragment,Fouts et al. Major structural differences and novel potential virulence,mechanisms from the genomes of multiple Campylobacter species,(er) PLoS Biol. 3 (1), doi 10.1371/journal.pbio.0030040 (2005); High confidence in function and specificity YP_665322.1 mosaic structure gene,CUP0956-like hypothetical protein, N-terminal,Campylobacter upsaliensis strain RM3195, gene: CUP0956 (1000),Fouts et al. Major structural differences and novel potential virulence,mechanisms from the genomes of multiple Campylobacter species,PLoS Biol. 3 (1), (2005),HP1116 C-terminal (957),jhp1044 C-terminal (1154); hypothetical protein YP_665327.1 note: syntenic region Hac1620-Hac1621; CUP0940(weak)-CUP0939; hypothetical protein YP_665331.1 mosaic structure gene, phage origin,conserved hypothetical protein ,mosaic structure gene,,CUP1551 (271), N-terminal, e-51,CUP0957 (304),C-terminal, e-53 [Campylobacter upsaliensis RM3195],Fouts et al. Major structural differences and novel potential virulence,mechanisms from the genomes of multiple Campylobacter species,PLoS Biol. 3 (1),(2005),Burkholderia cepacia phage Bcep22 gene gp50 , phage TerL (776), e-14, no mid region Summer,E.J., Cordova,M., Parkinson,B.C., Fuller,A.C.,Kitsopoulos,K., Parks,B., Rambo,L., Rothwell,S.,Mebane,L.M., Carlile,T.M., No,E.G., Gonzalez,C.M. and Young,R.F.,Complete nucleotide sequence of Bcep22, a bacteriophage isolated,from soil samples and specific for Burkholderia cepacia genomovar,III, Unpublished; hypothetical protein YP_665338.1 Campylobacter upsaliensis RM3195 CUP0941 (248) e-08,Fouts et al. Major structural differences and novel potential virulence,mechanisms from the genomes of multiple Campylobacter species,PLoS Biol. 3 (1), (2005); hypothetical protein YP_665343.1 weak CUP1445, CUP0949, CUP0949, CUP1445 e-03; hypothetical protein YP_665344.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_665345.1 conserved hypothetical protein YP_665346.1 conserved hypothetical protein YP_665347.1 (O25832) Hypothetical transport protein HP1234(O25832) Hypothetical transport protein HP1234; Specificity unclear YP_665348.1 conserved hypothetical protein YP_665349.1 (P73248) Dihydropteroate synthase (EC 2.5.1.15) (DHPS) (Dihydropteroate pyrophosphorylase)(P73248) Dihydropteroate synthase (EC 2.5.1.15) (DHPS) (Dihydropteroate pyrophosphorylase); High confidence in function and specificity YP_665350.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_665351.1 conserved hypothetical protein YP_665352.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_665353.1 hydrolyzes diadenosine polyphosphate YP_665354.1 High confidence in function and specificity YP_665355.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_665356.1 High confidence in function and specificity YP_665357.1 High confidence in function and specificity YP_665358.1 conserved hypothetical protein YP_665359.1 conserved hypothetical protein YP_665361.1 Probably together with 1655 part of a former gene. Contains real frameshift between 1655 and 1656.; hypothetical protein YP_665362.1 (P37051) Formyltetrahydrofolate deformylase (EC 3.5.1.10) (Formyl-FH(4) hydrolase)(P37051) Formyltetrahydrofolate deformylase (EC 3.5.1.10) (Formyl-FH(4) hydrolase); High confidence in function and specificity YP_665363.1 (Q55682) protease slr0021 (EC 3.4.21.-)(Q55682) protease slr0021 (EC 3.4.21.-); High confidence in function and specificity YP_665364.1 conserved hypothetical protein YP_665366.1 High confidence in function and specificity YP_665367.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_665368.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_665369.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_665370.1 High confidence in function and specificity YP_665372.1 (P21762) Probable peroxiredoxin (26 kDa antigen)(P21762) Probable peroxiredoxin (26 kDa antigen); High confidence in function and specificity YP_665373.1 (Q8X8V9) D-methionine-binding lipoprotein metQ precursor(Q8X8V9) D-methionine-binding lipoprotein metQ precursor; High confidence in function and specificity YP_665374.1 (P44469) Penicillin-binding protein 2 (PBP-2)(P44469) Penicillin-binding protein 2 (PBP-2); High confidence in function and specificity YP_665376.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_665377.1 (P06473) Glycoprotein B precursor(P06473) Glycoprotein B precursor; conserved hypothetical protein YP_665378.1 (P39631) Spore coat polysaccharide biosynthesis protein spsK(P39631) Spore coat polysaccharide biosynthesis protein spsK; conserved hypothetical protein YP_665379.1 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (EC 3.1.3.45) (KDO 8-P phosphatase)(Q8ZLS0) 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (EC 3.1.3.45) (KDO 8-P phosphatase); High confidence in function and specificity YP_665380.1 RlpA-like lipoprotein precursor; High confidence in function and specificity YP_665381.1 Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-) (Murein hydrolase D) (Regulatory protein dniR)Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-) (Murein hydrolase D) (Regulatory protein dniR); High confidence in function and specificity YP_665382.1 (P37545) deoxyribonuclease yabD (EC 3.1.21.-)(P37545) deoxyribonuclease yabD (EC 3.1.21.-); High confidence in function and specificity YP_665383.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_665384.1 Flagellar biosynthetic protein flhB; Function unclear YP_665385.1 part of the metNIQ transport system for methionine YP_665386.1 High confidence in function and specificity YP_665387.1 attaches phosphoethanolamine to lipid A at the 1 position of the disaccharide backbone in contrast to other gram-negative bacteria YP_665388.1 inner membrane enzyme; removes 1-phosphate groups from a number of lipid A precursors which provides a point of attachment for to moieties such as phosphoethanolamine which is attached by HP0022 YP_665389.1 Diaminopimelate decarboxylase (EC 4.1.1.20) (DAP decarboxylase); Function unclear YP_665390.1 High confidence in function and specificity YP_665396.1 Probable tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61)(O53271) Probable tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61); Specificity unclear YP_665397.1 synthesizes RNA primers at the replication forks YP_665398.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_665399.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_665400.1 note: prediction cause plasticity zone with synteny disruption,blastn omp match; hypothetical protein YP_665404.1 Function unclear YP_665411.1 High confidence in function and specificity YP_665412.1 Function unclear YP_665413.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_665415.1 High confidence in function and specificity YP_665416.1 High confidence in function and specificity YP_665417.1 High confidence in function and specificity YP_665418.1 COG3187, HslJ, Heat shock protein [Posttranslational modification, protein turnover,chaperones],pfam03724, META, Domain of unknown function (306). Small domain family found in proteins of of unknown function. Some are secreted and implicated in motility in bacteria. Also occurs in Leishmania spp. as an essential gene. Over-expression in L.amazonensis increases virulence. A pair of cysteine residues show correlated conservation, suggesting that they form a disulphide bond.; hypothetical protein YP_665421.1 High confidence in function and specificity YP_665422.1 Function unclear YP_665423.1 DUF864(Sanger) Helicobacter pylori protein of unknow; hypothetical protein YP_665424.1 High confidence in function and specificity YP_665425.1 catalyzes the formation of biotin from dethiobiotin and sulfur YP_665426.1 High confidence in function and specificity YP_665427.1 High confidence in function and specificity YP_665428.1 Function unclear YP_665429.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_665430.1 kdtB; Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_665431.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_665432.1 required for the assembly of the flagellar basal body P-ring YP_665433.1 High confidence in function and specificity YP_665434.1 Function unclear YP_665435.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_665436.1 Function unclear YP_665437.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_665438.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_665439.1 Specificity unclear YP_665441.1 Function unclear YP_665443.1 COG1566, EmrA, Multidrug resistance efflux pump [Defense mechanisms]; Specificity unclear YP_665445.1 (O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT; hypothetical protein YP_665446.1 High confidence in function and specificity YP_665447.1 Thioredoxin like.Thioredoxin like.; family membership YP_665448.1 conserved hypothetical protein YP_665449.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_665450.1 Important for the balance of metabolites in the pentose-phosphate pathway YP_665451.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_665452.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_665453.1 Membrane protein.Membrane protein.; conserved hypothetical protein YP_665455.1 (P39138) Arginase (EC 3.5.3.1)(P39138) Arginase (EC 3.5.3.1); High confidence in function and specificity YP_665456.1 Region start changed from 1535987 to 1536152 (165 bases) YP_665459.1 (Q99TF4) Alanine dehydrogenase 2 (EC 1.4.1.1)(Q99TF4) Alanine dehydrogenase 2 (EC 1.4.1.1); High confidence in function and specificity YP_665461.1 Function unclear YP_665462.1 Function unclear YP_665463.1 Function unclear YP_665465.1 (O25944) Probable inorganic polyphosphate/ATP-NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase)(O25944) Probable inorganic polyphosphate/ATP-NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase); High confidence in function and specificity YP_665466.1 (Q9ZJ80) DNA repair protein recN (Recombination protein N)(Q9ZJ80) DNA repair protein recN (Recombination protein N); High confidence in function and specificity YP_665467.1 Conserved hypothetical protein. Conserved to HPyl.Conserved hypothetical protein. Conserved to HPyl.; hypothetical protein YP_665468.1 Conserved hypothetical protein. Conserved to HPyl.Conserved hypothetical protein. Conserved to HPyl.; conserved hypothetical protein YP_665469.1 3'-5' exonuclease of DNA polymerase III YP_665470.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_665471.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_665472.1 Conserved hypothetical protein. Conserved to HPyl.Conserved hypothetical protein. Conserved to HPyl.; conserved hypothetical protein YP_665474.1 Conserved hypothetical protein. Conservation to HPyl.Conserved hypothetical protein. Conservation to HPyl.; conserved hypothetical protein YP_665475.1 (P44608) tRNA processing ribonuclease BN (EC 3.1.-.-) (RNase BN)(P44608) tRNA processing ribonuclease BN (EC 3.1.-.-) (RNase BN); hypothetical protein YP_665476.1 Fragment of (O25956) Biotin synthase (EC 2.8.1.6) (Biotin synthetase). Only C-terminal part exists.Fragment of (O25956) Biotin synthase (EC 2.8.1.6) (Biotin synthetase). Only C-terminal part exists.; High confidence in function and specificity YP_665477.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor YP_665478.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_665479.1 (O26059) Hypothetical protein HP1531/JHP1419; hypothetical protein YP_665480.1 (P51105) Dihydroflavonol-4-reductase (EC 1.1.1.219) (DFR) (Dihydrokaempferol 4-reductase); hypothetical protein YP_665481.1 similar to JHP0828; hypothetical protein YP_665482.1 similar to JHP0825; hypothetical protein YP_665486.1 replication protein repA,InterPro; Initiator RepB protein; hypothetical protein