-- dump date 20140619_112030 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 382638000001 SEQ_END SEQ_END NC_008229.1 1553927 1553927 DR NC_008229.1; contig end 1553927..1553927 Helicobacter acinonychis str. Sheeba 382638000002 SEQ_END SEQ_END NC_008230.1 3661 3661 DR NC_008230.1; contig end 3661..3661 Helicobacter acinonychis str. Sheeba YP_663869.1 CDS dnaA NC_008229.1 1 1350 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1..1350 Helicobacter acinonychis str. Sheeba 4177130 YP_663870.1 CDS Hac_0002 NC_008229.1 1575 3011 D hypothetical protein 1575..3011 Helicobacter acinonychis str. Sheeba 4176705 YP_663871.1 CDS exoA NC_008229.1 3162 3914 D AP endonuclease xth family; multifunctional DNA repair protein; has AP endonuclease, 3'-5' exonuclease, ribonuclease H, and 3'-phosphomonoesterase activities.; exodeoxyribonuclease III 3162..3914 Helicobacter acinonychis str. Sheeba 4177406 YP_663872.1 CDS Hac_0004 NC_008229.1 3911 4546 R hypothetical protein complement(3911..4546) Helicobacter acinonychis str. Sheeba 4176706 YP_663873.1 CDS Hac_0005 NC_008229.1 4550 4903 R hypothetical protein complement(4550..4903) Helicobacter acinonychis str. Sheeba 4176707 YP_663874.1 CDS recG NC_008229.1 5021 6886 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 5021..6886 Helicobacter acinonychis str. Sheeba 4177069 YP_663875.1 CDS mod fragment 1 NC_008229.1 6937 8328 D (P08763) Type III restriction-modification system EcoPI enzyme mod (EC 2.1.1.72) (EcoPI methyltransferase) (M.EcoPI); hypothetical protein; type III restriction-modification system methylation subunit fragment 1 6937..8328 Helicobacter acinonychis str. Sheeba 4176715 YP_663876.1 CDS mod fragment 2 NC_008229.1 8325 8915 D (P08763) Type III restriction-modification system EcoPI enzyme mod (EC 2.1.1.72) (EcoPI methyltransferase) (M.EcoPI); hypothetical protein; type III restriction-modification system methylation subunit fragment 2 8325..8915 Helicobacter acinonychis str. Sheeba 4176718 YP_663877.1 CDS res NC_008229.1 8916 11840 D (P08764) Type III restriction-modification system EcoPI enzyme res (EC 3.1.21.5); hypothetical protein; type III restriction enzyme 8916..11840 Helicobacter acinonychis str. Sheeba 4177075 YP_663878.1 CDS ECO57IR fragment 1 NC_008229.1 12025 13122 D (Q60301) Hypothetical protein MJECS02; hypothetical protein; type II DNA modification enzyme (methyltransferase) fragment 1 12025..13122 Helicobacter acinonychis str. Sheeba 4176389 YP_663879.1 CDS ECO57IR fragment 2 NC_008229.1 13240 15798 D type II DNA modification enzyme (methyltransferase); hypothetical protein; type II DNA modification enzyme (methyltransferase) fragment 2 13240..15798 Helicobacter acinonychis str. Sheeba 4176390 YP_663880.1 CDS trpA NC_008229.1 16548 17321 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(16548..17321) Helicobacter acinonychis str. Sheeba 4177492 YP_663881.1 CDS trpB NC_008229.1 17333 18514 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(17333..18514) Helicobacter acinonychis str. Sheeba 4177493 YP_663882.2 CDS trpC NC_008229.1 18516 19874 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(18516..19874) Helicobacter acinonychis str. Sheeba 4177494 YP_663883.1 CDS trpD NC_008229.1 19867 20874 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(19867..20874) Helicobacter acinonychis str. Sheeba 4176666 YP_663884.1 CDS trpG NC_008229.1 20871 21458 R TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(20871..21458) Helicobacter acinonychis str. Sheeba 4176668 YP_663885.1 CDS trpE NC_008229.1 21455 22957 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(21455..22957) Helicobacter acinonychis str. Sheeba 4176667 YP_663886.1 CDS fragment 2 NC_008229.1 23101 23901 R conserved hypothetical protein; High confidence in function and specificity; hypothetical protein complement(23101..23901) Helicobacter acinonychis str. Sheeba 4177219 YP_663887.1 CDS fragment 1 NC_008229.1 23963 24772 R membrane associated protein; High confidence in function and specificity; hypothetical protein complement(23963..24772) Helicobacter acinonychis str. Sheeba 4176337 YP_663888.1 CDS rfaJ NC_008229.1 24784 25887 R lipopolysaccharide 1,2-glucosyltransferase (rfaJ); High confidence in function and specificity; lipopolysaccharide biosynthesis protein complement(24784..25887) Helicobacter acinonychis str. Sheeba 4177080 YP_663889.1 CDS miaA NC_008229.1 25891 26691 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(25891..26691) Helicobacter acinonychis str. Sheeba 4176766 YP_663890.1 CDS Hac_0023 NC_008229.1 26792 27133 R Specificity unclear; hypothetical protein complement(26792..27133) Helicobacter acinonychis str. Sheeba 4176708 YP_663891.1 CDS Hac_0024 NC_008229.1 27193 27639 D NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 27193..27639 Helicobacter acinonychis str. Sheeba 4176709 YP_663892.1 CDS Hac_0029 NC_008229.1 32725 33159 R hypothetical protein complement(32725..33159) Helicobacter acinonychis str. Sheeba 4176710 YP_663893.1 CDS llm NC_008229.1 33765 34772 R undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; High confidence in function and specificity; methicillin resistance protein complement(33765..34772) Helicobacter acinonychis str. Sheeba 4177617 YP_663894.1 CDS pdxJ NC_008229.1 34902 35690 D involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 34902..35690 Helicobacter acinonychis str. Sheeba 4176743 YP_663895.1 CDS pdxA NC_008229.1 35692 36624 D catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 35692..36624 Helicobacter acinonychis str. Sheeba 4176742 YP_663896.1 CDS fragment 1 NC_008229.1 36694 37080 D conserved hypothetical protein; High confidence in function and specificity; hypothetical protein 36694..37080 Helicobacter acinonychis str. Sheeba 4176338 YP_663897.1 CDS fragment 2 NC_008229.1 37047 37391 D similar to jhp1463; Function unclear; hypothetical protein 37047..37391 Helicobacter acinonychis str. Sheeba 4177220 YP_663898.1 CDS omp1 fragment 4 NC_008229.1 37610 37750 R outer membrane protein, fragment 4; hypothetical protein; hypothetical protein complement(37610..37750) Helicobacter acinonychis str. Sheeba 4176469 YP_663899.1 CDS omp1 fragment 3 NC_008229.1 37807 38277 R outer membrane protein, fragment 3; hypothetical protein; hypothetical protein complement(37807..38277) Helicobacter acinonychis str. Sheeba 4176468 YP_663900.1 CDS omp1 fragment 2 NC_008229.1 38337 38546 R outer membrane protein, fragment 2; hypothetical protein; hypothetical protein complement(38337..38546) Helicobacter acinonychis str. Sheeba 4176467 YP_663901.1 CDS omp1 fragment 1 NC_008229.1 38662 39033 R outer membrane protein, fragment 1; hypothetical protein; hypothetical protein complement(38662..39033) Helicobacter acinonychis str. Sheeba 4176466 YP_663902.1 CDS gltA NC_008229.1 39328 40608 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(39328..40608) Helicobacter acinonychis str. Sheeba 4177259 YP_663903.1 CDS icdA NC_008229.1 40811 42088 D (Q9ZN36) Isocitrate dehydrogenase [NADP] (EC 1.1.1.42) (Oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP); High confidence in function and specificity; isocitrate dehydrogenase 40811..42088 Helicobacter acinonychis str. Sheeba 4177676 YP_663904.1 CDS Hac_0042 NC_008229.1 42133 42651 D similar to HP0028; Specificity unclear; hypothetical protein 42133..42651 Helicobacter acinonychis str. Sheeba 4176711 YP_663905.1 CDS bioD NC_008229.1 42628 43284 R (Q9ZN34) Dethiobiotin synthetase (EC 6.3.3.3) (Dethiobiotin synthase) (DTB synthetase) (DTBS); High confidence in function and specificity; hypothetical protein complement(42628..43284) Helicobacter acinonychis str. Sheeba 4177117 YP_663906.1 CDS Hac_0044 NC_008229.1 43392 43805 D Hypothetical protein similar to HP0031/JHP0027; High confidence in function and specificity; hypothetical protein 43392..43805 Helicobacter acinonychis str. Sheeba 4176712 YP_663907.1 CDS Hac_0045 NC_008229.1 43807 44082 D similar to HP0032/JHP0028; Specificity unclear; hypothetical protein 43807..44082 Helicobacter acinonychis str. Sheeba 4176160 YP_663908.1 CDS clpA NC_008229.1 44082 46301 D (P15716) ATP-dependent Clp protease ATP-binding subunit clpA; High confidence in function and specificity; ATP-dependent Clp protease, ATP-binding subunit ClpA 44082..46301 Helicobacter acinonychis str. Sheeba 4176606 YP_663909.1 CDS panD NC_008229.1 46303 46641 D Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 46303..46641 Helicobacter acinonychis str. Sheeba 4176733 YP_663910.1 CDS Hac_0048 NC_008229.1 46652 46945 D similar to HP0035/JHP0031; High confidence in function and specificity; hypothetical protein 46652..46945 Helicobacter acinonychis str. Sheeba 4176161 YP_663911.1 CDS Hac_0049 NC_008229.1 46945 47940 D similar to HP0036; hypothetical protein; hypothetical protein 46945..47940 Helicobacter acinonychis str. Sheeba 4176162 YP_663912.1 CDS Hac_0050 NC_008229.1 47948 49012 D similar to JHP0033; Function unclear; hypothetical protein 47948..49012 Helicobacter acinonychis str. Sheeba 4176163 YP_663913.1 CDS comB1 NC_008229.1 49172 49915 D (Q9ZDN8) Hypothetical protein RP289; Function unclear; ComB1 protein 49172..49915 Helicobacter acinonychis str. Sheeba 4176891 YP_663914.1 CDS comB2 NC_008229.1 49915 50865 D (P17799) VirB9 protein precursor; High confidence in function and specificity; ComB2 protein 49915..50865 Helicobacter acinonychis str. Sheeba 4176892 YP_663915.1 CDS comB3 NC_008229.1 50858 51994 D (P55406) Probable conjugal transfer protein trbI; High confidence in function and specificity; ComB3 protein 50858..51994 Helicobacter acinonychis str. Sheeba 4176893 YP_663916.1 CDS algA NC_008229.1 52044 53471 D (P26340) Mannose-1-phosphate guanylyltransferase [GDP] (EC 2.7.7.22) (GDP-mannose pyrophosphorylase) (GMP); High confidence in function and specificity; mannose-6-phosphate isomerase / mannose-1-phosphate guanylyltransferase 52044..53471 Helicobacter acinonychis str. Sheeba 4177707 YP_663917.1 CDS gmd NC_008229.1 53481 54626 D High confidence in function and specificity; hypothetical protein 53481..54626 Helicobacter acinonychis str. Sheeba 4177266 YP_663918.1 CDS wbcJ NC_008229.1 54619 55551 D (P32055) GDP-L-fucose synthetase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-35-epimerase-4-reductase); High confidence in function and specificity; GDP-fucose synthetase 54619..55551 Helicobacter acinonychis str. Sheeba 4176637 YP_663919.1 CDS tyrA NC_008229.1 56017 56844 R catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase complement(56017..56844) Helicobacter acinonychis str. Sheeba 4176678 YP_663920.1 CDS lon NC_008229.1 56846 59341 R High confidence in function and specificity; ATP-dependent protease La complement(56846..59341) Helicobacter acinonychis str. Sheeba 4177618 YP_663921.1 CDS comL NC_008229.1 59382 60035 R (Q9L7A6) Hypothetical lipoprotein HD0470 precursor; High confidence in function and specificity; competence lipoprotein complement(59382..60035) Helicobacter acinonychis str. Sheeba 4176895 YP_663922.1 CDS Hac_0061 NC_008229.1 60252 60641 D binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 60252..60641 Helicobacter acinonychis str. Sheeba 4176164 YP_663923.1 CDS fabZ NC_008229.1 60812 61288 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 60812..61288 Helicobacter acinonychis str. Sheeba 4177412 YP_663924.1 CDS lpxA NC_008229.1 61291 62103 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 61291..62103 Helicobacter acinonychis str. Sheeba 4177620 YP_663925.1 CDS clpX NC_008229.1 62105 63415 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 62105..63415 Helicobacter acinonychis str. Sheeba 4176889 YP_663926.1 CDS mreB NC_008229.1 63468 64511 D functions in MreBCD complex in some organisms; rod shape-determining protein MreB 63468..64511 Helicobacter acinonychis str. Sheeba 4176726 YP_663927.1 CDS mreC NC_008229.1 64516 65262 D in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 64516..65262 Helicobacter acinonychis str. Sheeba 4176727 YP_663928.1 CDS fragment 1 NC_008229.1 65307 66404 D (P32678) Protein yijP,similar to JHP1312; High confidence in function and specificity; metal-dependent hydrolase fragment 1 65307..66404 Helicobacter acinonychis str. Sheeba 4176339 YP_663929.1 CDS fragment 2 NC_008229.1 66385 66969 D similar to JHP1312; Function unclear; metal-dependent hydrolase fragment 2 66385..66969 Helicobacter acinonychis str. Sheeba 4177221 YP_663930.1 CDS nusA NC_008229.1 67196 68383 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(67196..68383) Helicobacter acinonychis str. Sheeba 4176462 YP_663931.1 CDS selA NC_008229.1 68449 69627 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(68449..69627) Helicobacter acinonychis str. Sheeba 4177173 YP_663932.1 CDS frpB NC_008229.1 69844 72435 R Function unclear; iron-regulated outer membrane protein complement(69844..72435) Helicobacter acinonychis str. Sheeba 4176521 YP_663933.1 CDS Hac_0073 NC_008229.1 72588 72914 R similar to HP1511; Function unclear; hypothetical protein complement(72588..72914) Helicobacter acinonychis str. Sheeba 4176165 YP_663934.1 CDS folB NC_008229.1 72898 73251 R (P46362) Dihydroneopterin aldolase (EC 4.1.2.25) (DHNA); Function unclear; hypothetical protein complement(72898..73251) Helicobacter acinonychis str. Sheeba 4177508 YP_663935.1 CDS Hac_0075 NC_008229.1 73248 73910 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY complement(73248..73910) Helicobacter acinonychis str. Sheeba 4176166 YP_663936.1 CDS Hac_0076 NC_008229.1 74014 75384 D similar to HP1508; Specificity unclear; ferredoxin-like protein 74014..75384 Helicobacter acinonychis str. Sheeba 4176167 YP_663937.1 CDS lys1 NC_008229.1 75393 76592 R (Q9P4R4) Saccharopine dehydrogenase [NADP+ L-glutamate forming] (EC 1.5.1.10) (Saccharopine reductase),similar to HP1507; Function unclear; hypothetical protein complement(75393..76592) Helicobacter acinonychis str. Sheeba 4177627 YP_663938.1 CDS gltS NC_008229.1 76679 77905 D (P45240) Sodium/glutamate symport carrier protein (Glutamate permease),similar to HP1506; High confidence in function and specificity; sodium/glutamate symport carrier protein 76679..77905 Helicobacter acinonychis str. Sheeba 4177261 YP_663939.1 CDS ribD NC_008229.1 77902 78936 D (O24750) Riboflavin biosynthesis protein ribD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) (HTP reductase)]; High confidence in function and specificity; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase 77902..78936 Helicobacter acinonychis str. Sheeba 4177089 YP_663940.1 CDS Hac_0080 NC_008229.1 78918 79634 D similar to HP1504; Specificity unclear; hypothetical protein 78918..79634 Helicobacter acinonychis str. Sheeba 4176168 YP_663941.1 CDS copA NC_008229.1 79645 81984 D (Q8Z8S4) Copper-transporting P-type ATPase (EC 3.6.3.4); High confidence in function and specificity; cation transporter E1-E2 family ATPase 79645..81984 Helicobacter acinonychis str. Sheeba 4176896 YP_663942.1 CDS hypE NC_008229.1 82141 83139 R (P42034) Hydrogenase expression/formation protein hypE; High confidence in function and specificity; hydrogenase expression/formation protein complement(82141..83139) Helicobacter acinonychis str. Sheeba 4177672 YP_663943.1 CDS hypF NC_008229.1 83142 85394 R HypF family transcriptional regulator,similar to HP0048; High confidence in function and specificity; HypF family transcriptional regulator complement(83142..85394) Helicobacter acinonychis str. Sheeba 4177673 YP_663944.1 CDS Hac_0084 NC_008229.1 85391 86383 R similar to HP0049; Function unclear; hypothetical protein complement(85391..86383) Helicobacter acinonychis str. Sheeba 4176169 YP_663945.1 CDS dpnA fragment 3 NC_008229.1 86453 86668 R (O30569) Modification methylase SmeIP (EC 2.1.1.72) (Adenine-specific methyltransferase SmeIP) (M.SmeI) (M.CcrMI); hypothetical protein; adenine specific DNA methyltransferase fragment 3 complement(86453..86668) Helicobacter acinonychis str. Sheeba 4176377 YP_663946.1 CDS dpnA fragment 2 NC_008229.1 86708 86815 R adenine specific DNA methyltransferase fragment 2 complement(86708..86815) Helicobacter acinonychis str. Sheeba 4176376 YP_663947.1 CDS dpnA fragment 1 NC_008229.1 86988 87089 R dpnA fragment; hypothetical protein; adenine specific DNA methyltransferase fragment 1 complement(86988..87089) Helicobacter acinonychis str. Sheeba 4176375 YP_663948.1 CDS DDEM fragment 4 NC_008229.1 87152 87319 R (P34881) DNA (cytosine-5)-methyltransferase AthI (EC 2.1.1.37) (DNA methyltransferase AthI) (DNA Metase AthI) (M.AthI); hypothetical protein; cytosine specific DNA methyltransferase fragment 4 complement(87152..87319) Helicobacter acinonychis str. Sheeba 4177121 YP_663949.1 CDS DDEM fragment 3 NC_008229.1 87354 87605 R (P05302) Modification methylase DdeI (EC 2.1.1.37) (Cytosine-specific methyltransferase DdeI) (M.DdeI); hypothetical protein; cytosine specific DNA methyltransferase fragment 3 complement(87354..87605) Helicobacter acinonychis str. Sheeba 4176412 YP_663950.1 CDS DDEM fragment 2 NC_008229.1 87595 87900 R (P50192) Modification methylase HphIA (EC 2.1.1.37) (Cytosine-specific methyltransferase HphIA) (M.HphIA) (M.Hphi(C)); hypothetical protein; cytosine specific DNA methyltransferase fragment 2 complement(87595..87900) Helicobacter acinonychis str. Sheeba 4176411 YP_663951.1 CDS DDEM fragment 1 NC_008229.1 87983 88228 R (P94147) Modification methylase AgeI (EC 2.1.1.37) (Cytosine-specific methyltransferase AgeI) (M.AgeI); hypothetical protein; cytosine specific DNA methyltransferase fragment 1 complement(87983..88228) Helicobacter acinonychis str. Sheeba 4176410 YP_663952.1 CDS Hac_0095 NC_008229.1 88497 89654 D Region start changed from 88584 to 88497 (87 bases); outer membrane protein 2 88497..89654 Helicobacter acinonychis str. Sheeba 4176170 YP_663953.1 CDS Hac_0096 NC_008229.1 89973 91412 R Function unclear; hypothetical protein complement(89973..91412) Helicobacter acinonychis str. Sheeba 4176171 YP_663954.1 CDS Hac_0097 NC_008229.1 91509 92543 R similar to HP1284; High confidence in function and specificity; hypothetical protein complement(91509..92543) Helicobacter acinonychis str. Sheeba 4176172 YP_663955.1 CDS Hac_0098 NC_008229.1 92599 93375 R similar to HP1285; Specificity unclear; hypothetical protein complement(92599..93375) Helicobacter acinonychis str. Sheeba 4176173 YP_663956.1 CDS Hac_0099 NC_008229.1 93524 94072 D similar to HP1286; High confidence in function and specificity; hypothetical protein 93524..94072 Helicobacter acinonychis str. Sheeba 4176174 YP_663957.1 CDS Hac_0101 NC_008229.1 94509 94691 D hypothetical protein 94509..94691 Helicobacter acinonychis str. Sheeba 4176175 YP_663958.1 CDS murB NC_008229.1 94952 95731 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(94952..95731) Helicobacter acinonychis str. Sheeba 4177651 YP_663959.1 CDS fliQ NC_008229.1 95735 96001 R with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ complement(95735..96001) Helicobacter acinonychis str. Sheeba 4177503 YP_663960.1 CDS fliI NC_008229.1 96012 97316 R involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase complement(96012..97316) Helicobacter acinonychis str. Sheeba 4177499 YP_663961.1 CDS virB11 NC_008229.1 97317 98231 R Function unclear; virB11 protein complement(97317..98231) Helicobacter acinonychis str. Sheeba 4176633 YP_663962.1 CDS ileS NC_008229.1 98248 101013 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(98248..101013) Helicobacter acinonychis str. Sheeba 4177677 YP_663963.1 CDS Hac_0109 NC_008229.1 101041 101298 R Hypothetical protein similar to HP1423/JHP1318; High confidence in function and specificity; hypothetical protein complement(101041..101298) Helicobacter acinonychis str. Sheeba 4176176 YP_663964.1 CDS Hac_0110 NC_008229.1 101400 102026 D similar to HP1424; hypothetical protein; hypothetical protein 101400..102026 Helicobacter acinonychis str. Sheeba 4176177 YP_663965.1 CDS Hac_0111 NC_008229.1 102492 102740 R hypothetical protein complement(102492..102740) Helicobacter acinonychis str. Sheeba 4176178 YP_663966.1 CDS ksgA NC_008229.1 102975 103790 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 102975..103790 Helicobacter acinonychis str. Sheeba 4176138 YP_663967.1 CDS Hac_0114 NC_008229.1 103827 105893 D Hypothetical protein similar to HP1430; Specificity unclear; hypothetical protein 103827..105893 Helicobacter acinonychis str. Sheeba 4176179 YP_663968.1 CDS Hac_0115 NC_008229.1 105877 106866 D Hypothetical protein similar to HP1429; High confidence in function and specificity; hypothetical protein 105877..106866 Helicobacter acinonychis str. Sheeba 4176180 YP_663969.1 CDS Hac_0116 NC_008229.1 106863 107924 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 106863..107924 Helicobacter acinonychis str. Sheeba 4176181 YP_663970.1 CDS Hac_0118 NC_008229.1 108112 108477 R hypothetical protein complement(108112..108477) Helicobacter acinonychis str. Sheeba 4176182 YP_663971.1 CDS maf NC_008229.1 108593 109156 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(108593..109156) Helicobacter acinonychis str. Sheeba 4176753 YP_663972.1 CDS alaS NC_008229.1 109158 111701 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(109158..111701) Helicobacter acinonychis str. Sheeba 4177705 YP_663973.1 CDS Hac_0122 NC_008229.1 111819 112049 D similar to HP1242; Function unclear; hypothetical protein 111819..112049 Helicobacter acinonychis str. Sheeba 4176183 YP_663974.1 CDS ccpA NC_008229.1 112333 113385 R (P14532) Cytochrome c551 peroxidase precursor (EC 1.11.1.5) (Cytochrome c peroxidase) (CCP); High confidence in function and specificity; cytochrome c551 peroxidase complement(112333..113385) Helicobacter acinonychis str. Sheeba 4176594 YP_663975.1 CDS dnaE NC_008229.1 113552 117181 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 113552..117181 Helicobacter acinonychis str. Sheeba 4177132 YP_663976.1 CDS yciL NC_008229.1 117178 117942 D (P55986) Hypothetical pseudouridine synthase HP1459 (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase); High confidence in function and specificity; pseudouridylate synthase 117178..117942 Helicobacter acinonychis str. Sheeba 4177710 YP_663977.1 CDS trxA NC_008229.1 118006 118320 D (P48384) Thioredoxin M-type chloroplast precursor (TRX-M); Function unclear; thioredoxin 118006..118320 Helicobacter acinonychis str. Sheeba 4176671 YP_663978.1 CDS Hac_0127 NC_008229.1 118570 118728 D hypothetical protein 118570..118728 Helicobacter acinonychis str. Sheeba 4176184 YP_663979.1 CDS Hac_0128 NC_008229.1 118755 118931 D hypothetical protein 118755..118931 Helicobacter acinonychis str. Sheeba 4176185 YP_663980.1 CDS Hac_0129 NC_008229.1 119031 119390 D hypothetical protein 119031..119390 Helicobacter acinonychis str. Sheeba 4176186 YP_663981.1 CDS Hac_0130 NC_008229.1 119542 119703 D hypothetical protein 119542..119703 Helicobacter acinonychis str. Sheeba 4176187 YP_663982.1 CDS fumC NC_008229.1 119764 121155 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 119764..121155 Helicobacter acinonychis str. Sheeba 4177017 YP_663983.1 CDS rnhB NC_008229.1 121877 122458 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 121877..122458 Helicobacter acinonychis str. Sheeba 4177096 YP_663984.1 CDS Hac_0133 NC_008229.1 122455 123042 R hypothetical protein complement(122455..123042) Helicobacter acinonychis str. Sheeba 4176188 YP_663985.1 CDS Hac_0134 NC_008229.1 123262 124350 R similar to HP1321; Specificity unclear; hypothetical protein complement(123262..124350) Helicobacter acinonychis str. Sheeba 4176189 YP_663986.1 CDS rpsJ NC_008229.1 124560 124874 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 124560..124874 Helicobacter acinonychis str. Sheeba 4177150 YP_663987.1 CDS rplC NC_008229.1 124908 125483 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 124908..125483 Helicobacter acinonychis str. Sheeba 4176836 YP_663988.1 CDS rplD NC_008229.1 125517 126164 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 125517..126164 Helicobacter acinonychis str. Sheeba 4176837 YP_663989.1 CDS rplW NC_008229.1 126168 126449 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 126168..126449 Helicobacter acinonychis str. Sheeba 4176853 YP_663990.1 CDS rplB NC_008229.1 126465 127295 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 126465..127295 Helicobacter acinonychis str. Sheeba 4176835 YP_663991.1 CDS rpsS NC_008229.1 127307 127588 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 127307..127588 Helicobacter acinonychis str. Sheeba 4177158 YP_663992.1 CDS rplV NC_008229.1 127598 127966 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 127598..127966 Helicobacter acinonychis str. Sheeba 4176852 YP_663993.1 CDS rpsC NC_008229.1 127970 128674 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 127970..128674 Helicobacter acinonychis str. Sheeba 4177143 YP_663994.1 CDS rplP NC_008229.1 128677 129102 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 128677..129102 Helicobacter acinonychis str. Sheeba 4176847 YP_663995.1 CDS rpmC NC_008229.1 129104 129289 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 129104..129289 Helicobacter acinonychis str. Sheeba 4176858 YP_663996.1 CDS rpsQ NC_008229.1 129303 129563 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 129303..129563 Helicobacter acinonychis str. Sheeba 4177156 YP_663997.1 CDS rplN NC_008229.1 129566 129934 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 129566..129934 Helicobacter acinonychis str. Sheeba 4176845 YP_663998.1 CDS rplX NC_008229.1 129934 130155 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 129934..130155 Helicobacter acinonychis str. Sheeba 4176854 YP_663999.1 CDS rplE NC_008229.1 130167 130712 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 130167..130712 Helicobacter acinonychis str. Sheeba 4176838 YP_003856780.1 CDS Hac_1800 NC_008229.1 130722 130907 D 30S ribosomal protein S14 130722..130907 Helicobacter acinonychis str. Sheeba 9711836 YP_664000.1 CDS rpsH NC_008229.1 130917 131312 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 130917..131312 Helicobacter acinonychis str. Sheeba 4177148 YP_664001.1 CDS rplF NC_008229.1 131323 131859 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 131323..131859 Helicobacter acinonychis str. Sheeba 4176839 YP_664002.1 CDS rplR NC_008229.1 131873 132229 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 131873..132229 Helicobacter acinonychis str. Sheeba 4176849 YP_664003.1 CDS rpsE NC_008229.1 132226 132687 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 132226..132687 Helicobacter acinonychis str. Sheeba 4177145 YP_664004.1 CDS rplO NC_008229.1 132705 133106 D late assembly protein; 50S ribosomal protein L15 132705..133106 Helicobacter acinonychis str. Sheeba 4176846 YP_664005.1 CDS secY NC_008229.1 133149 134411 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 133149..134411 Helicobacter acinonychis str. Sheeba 4177172 YP_664006.1 CDS map NC_008229.1 134411 135172 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 134411..135172 Helicobacter acinonychis str. Sheeba 4176754 YP_664007.1 CDS infA NC_008229.1 135172 135390 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 135172..135390 Helicobacter acinonychis str. Sheeba 4177680 YP_664008.1 CDS rpsM NC_008229.1 135585 135947 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 135585..135947 Helicobacter acinonychis str. Sheeba 4177153 YP_664009.1 CDS rpsK NC_008229.1 135971 136366 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 135971..136366 Helicobacter acinonychis str. Sheeba 4177151 YP_664010.1 CDS rpsD NC_008229.1 136376 137002 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 136376..137002 Helicobacter acinonychis str. Sheeba 4177144 YP_664011.1 CDS rpoA NC_008229.1 137014 138048 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 137014..138048 Helicobacter acinonychis str. Sheeba 4176862 YP_664012.1 CDS rplQ NC_008229.1 138048 138398 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 138048..138398 Helicobacter acinonychis str. Sheeba 4176848 YP_664013.1 CDS Hac_0162 NC_008229.1 138736 140208 D similar to HP0018; Function unclear; hypothetical protein 138736..140208 Helicobacter acinonychis str. Sheeba 4176190 YP_664014.1 CDS Hac_0163 NC_008229.1 140221 140856 D similar to HP1457; Function unclear; hypothetical protein 140221..140856 Helicobacter acinonychis str. Sheeba 4176191 YP_664015.1 CDS lpp20 NC_008229.1 140878 141408 D (P53436) LPP20 lipoprotein precursor,similar to HP1456; High confidence in function and specificity; lipoprotein 140878..141408 Helicobacter acinonychis str. Sheeba 4177619 YP_664016.1 CDS Hac_0165 NC_008229.1 141415 141771 D similar to HP1455; hypothetical protein; hypothetical protein 141415..141771 Helicobacter acinonychis str. Sheeba 4176192 YP_664017.1 CDS Hac_0166 NC_008229.1 141771 142673 D similar to HP1454; hypothetical protein; hypothetical protein 141771..142673 Helicobacter acinonychis str. Sheeba 4176193 YP_664018.1 CDS trmE NC_008229.1 142790 144142 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE complement(142790..144142) Helicobacter acinonychis str. Sheeba 4177474 YP_664019.1 CDS Hac_0168 NC_008229.1 144135 144947 R similar to HP1451; hypothetical protein; hypothetical protein complement(144135..144947) Helicobacter acinonychis str. Sheeba 4176194 YP_664020.1 CDS Hac_0169 NC_008229.1 144958 146598 R functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC complement(144958..146598) Helicobacter acinonychis str. Sheeba 4176195 YP_664021.1 CDS Hac_0170 NC_008229.1 146604 146921 R similar to HP1449; High confidence in function and specificity; hypothetical protein complement(146604..146921) Helicobacter acinonychis str. Sheeba 4176196 YP_664022.1 CDS rnpA NC_008229.1 146932 147393 R (Q9ZJH0) Ribonuclease P protein component (EC 3.1.26.5) (RNaseP protein) (RNase P protein) (Protein C5); High confidence in function and specificity; ribonuclease P protein component complement(146932..147393) Helicobacter acinonychis str. Sheeba 4177097 YP_664023.1 CDS exbD NC_008229.1 147572 147967 R (O25987) biopolymer transport exbD-like protein; High confidence in function and specificity; hypothetical protein complement(147572..147967) Helicobacter acinonychis str. Sheeba 4177403 YP_664024.1 CDS exbB NC_008229.1 147978 148430 R (Q9ZJH1) biopolymer transport exbB-like protein; High confidence in function and specificity; biopolymer transport protein complement(147978..148430) Helicobacter acinonychis str. Sheeba 4177400 YP_664025.1 CDS smpB NC_008229.1 148433 148891 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(148433..148891) Helicobacter acinonychis str. Sheeba 4177458 YP_664026.1 CDS ipk NC_008229.1 148888 149694 R catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(148888..149694) Helicobacter acinonychis str. Sheeba 4177683 YP_664027.1 CDS csrA NC_008229.1 149691 149921 R affects carbohydrate metabolism, has regulatory role in many processes; carbon storage regulator complement(149691..149921) Helicobacter acinonychis str. Sheeba 4176902 YP_664028.1 CDS ppi NC_008229.1 149934 150422 R (Q9ZJH5) Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase); High confidence in function and specificity; peptidyl-prolyl cis-trans isomerase complement(149934..150422) Helicobacter acinonychis str. Sheeba 4176553 YP_664029.1 CDS Hac_0178 NC_008229.1 150551 151330 D hypothetical protein 150551..151330 Helicobacter acinonychis str. Sheeba 4176197 YP_664030.1 CDS Hac_0179 NC_008229.1 153445 153879 R hypothetical protein complement(153445..153879) Helicobacter acinonychis str. Sheeba 4176198 YP_664031.1 CDS fragment 5 NC_008229.1 154245 154412 R restriction enzyme fragment 5 complement(154245..154412) Helicobacter acinonychis str. Sheeba 4176516 YP_664032.1 CDS fragment 4 NC_008229.1 154535 154717 R restriction enzyme fragment 4 complement(154535..154717) Helicobacter acinonychis str. Sheeba 4177296 YP_664033.1 CDS fragment 3 NC_008229.1 154714 154866 R restriction enzyme fragment 3 complement(154714..154866) Helicobacter acinonychis str. Sheeba 4177042 YP_664034.1 CDS fragment 2 NC_008229.1 154899 155105 R fragmented gene homologous to HP1371; hypothetical protein; restriction enzyme fragment 2 complement(154899..155105) Helicobacter acinonychis str. Sheeba 4177222 YP_664035.1 CDS fragment 1 NC_008229.1 155135 155251 R restriction enzyme fragment 1 complement(155135..155251) Helicobacter acinonychis str. Sheeba 4176340 YP_664036.1 CDS Hac_0185 NC_008229.1 155403 156275 D (Q58392) Modification methylase MjaI (EC 2.1.1.113) (N-4 cytosine-specific methyltransferase MjaI) (M.MjaI); High confidence in function and specificity; modification methylase mjai 155403..156275 Helicobacter acinonychis str. Sheeba 4176297 YP_664037.1 CDS mod fragment 1 NC_008229.1 156268 156540 D (P23192) Modification methylase MboII (EC 2.1.1.72) (Adenine-specific methyltransferase MboII) (M.MboII); High confidence in function and specificity; type IIS restriction enzyme M1 protein fragment 1 156268..156540 Helicobacter acinonychis str. Sheeba 4176716 YP_664038.1 CDS mod fragment 2 NC_008229.1 156528 157043 D (P23192) Modification methylase MboII (EC 2.1.1.72) (Adenine-specific methyltransferase MboII) (M.MboII); High confidence in function and specificity; type IIS restriction enzyme M1 protein fragment 2 156528..157043 Helicobacter acinonychis str. Sheeba 4176719 YP_664039.1 CDS Hac_0188 NC_008229.1 157172 158341 D (P23191) Type IIS restriction enzyme MboII (EC 3.1.21.4) (Endonuclease MboII) (R.MboII); High confidence in function and specificity; typeIIS restriction enzyme 157172..158341 Helicobacter acinonychis str. Sheeba 4176298 YP_664040.1 CDS Hac_0190 NC_008229.1 158782 159423 D Function unclear; two-component regulator 158782..159423 Helicobacter acinonychis str. Sheeba 4176299 YP_664041.1 CDS Hac_0191 NC_008229.1 159479 160591 D Specificity unclear; signal-transducing protein, histidine kinase 159479..160591 Helicobacter acinonychis str. Sheeba 4176300 YP_664042.1 CDS Hac_0192 NC_008229.1 160594 161988 D similar to HP1363; Specificity unclear; hypothetical protein 160594..161988 Helicobacter acinonychis str. Sheeba 4176301 YP_664043.1 CDS dnaB NC_008229.1 162000 163460 D unwinds double stranded DNA; replicative DNA helicase 162000..163460 Helicobacter acinonychis str. Sheeba 4177131 YP_664044.1 CDS comE NC_008229.1 163457 164773 D (P51973) Competence protein comE3, DNA transfer protein; High confidence in function and specificity; DNA transfer protein ComE 163457..164773 Helicobacter acinonychis str. Sheeba 4176894 YP_664045.1 CDS ubiA NC_008229.1 164844 165728 D UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; prenyltransferase 164844..165728 Helicobacter acinonychis str. Sheeba 4176680 YP_664046.1 CDS Hac_0196 NC_008229.1 165730 166215 D similar to HP1359; hypothetical protein; hypothetical protein 165730..166215 Helicobacter acinonychis str. Sheeba 4176302 YP_664047.1 CDS Hac_0197 NC_008229.1 166228 166734 D similar to HP1358; hypothetical protein; hypothetical protein 166228..166734 Helicobacter acinonychis str. Sheeba 4176303 YP_664048.1 CDS psd NC_008229.1 166728 167531 D catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 166728..167531 Helicobacter acinonychis str. Sheeba 4176569 YP_664049.1 CDS nadA NC_008229.1 167521 168531 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 167521..168531 Helicobacter acinonychis str. Sheeba 4177662 YP_664050.1 CDS nadC NC_008229.1 168531 169352 D catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 168531..169352 Helicobacter acinonychis str. Sheeba 4177663 YP_664051.1 CDS fragment 1 NC_008229.1 169378 171972 D (Q47282) Type I restriction enzyme EcoEI M protein (EC 2.1.1.72) (M.EcoEI); hypothetical protein; adenine specific DNA methyltransferase fragment 1 169378..171972 Helicobacter acinonychis str. Sheeba 4176341 YP_664052.1 CDS fragment 2 NC_008229.1 172032 172733 D adenine specific DNA methyltransferase fragment 2 172032..172733 Helicobacter acinonychis str. Sheeba 4177223 YP_664053.1 CDS Hac_0204 NC_008229.1 173153 173458 D hypothetical protein 173153..173458 Helicobacter acinonychis str. Sheeba 4176304 YP_664054.1 CDS Hac_0205 NC_008229.1 173498 173992 D hypothetical protein 173498..173992 Helicobacter acinonychis str. Sheeba 4176305 YP_664055.1 CDS pnuC NC_008229.1 174178 174840 D (Q57425) Hypothetical protein HI1077.1; High confidence in function and specificity; hypothetical protein 174178..174840 Helicobacter acinonychis str. Sheeba 4176786 YP_664056.1 CDS Hac_0207 NC_008229.1 174837 175439 D High confidence in function and specificity; hypothetical protein 174837..175439 Helicobacter acinonychis str. Sheeba 4176306 YP_664057.1 CDS Hac_0208 NC_008229.1 175488 176681 D Function unclear; hypothetical protein 175488..176681 Helicobacter acinonychis str. Sheeba 4176307 YP_664058.1 CDS algC NC_008229.1 176660 178048 R (P26276) Phosphomannomutase/phosphoglucomutase (EC 5.4.2.8) (EC 5.4.2.2) (PMM / PGM); High confidence in function and specificity; hypothetical protein complement(176660..178048) Helicobacter acinonychis str. Sheeba 4177708 YP_664059.1 CDS pflA NC_008229.1 178049 180433 R flagellar functional protein; hypothetical protein; paralysed flagella protein complement(178049..180433) Helicobacter acinonychis str. Sheeba 4176750 YP_664060.1 CDS nuoN NC_008229.1 180453 181931 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(180453..181931) Helicobacter acinonychis str. Sheeba 4176460 YP_664061.1 CDS nuoM NC_008229.1 181918 183456 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M complement(181918..183456) Helicobacter acinonychis str. Sheeba 4176459 YP_664062.1 CDS nuoL NC_008229.1 183460 185298 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L complement(183460..185298) Helicobacter acinonychis str. Sheeba 4176458 YP_664063.1 CDS nuoK NC_008229.1 185301 185603 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K complement(185301..185603) Helicobacter acinonychis str. Sheeba 4176457 YP_664064.1 CDS nuoJ NC_008229.1 185600 186148 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J complement(185600..186148) Helicobacter acinonychis str. Sheeba 4176456 YP_664065.1 CDS nuoI NC_008229.1 186141 186803 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(186141..186803) Helicobacter acinonychis str. Sheeba 4176455 YP_664066.1 CDS nuoH NC_008229.1 186813 187802 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(186813..187802) Helicobacter acinonychis str. Sheeba 4176454 YP_664067.1 CDS nuoG NC_008229.1 187799 190291 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G complement(187799..190291) Helicobacter acinonychis str. Sheeba 4176453 YP_664068.1 CDS nuoF NC_008229.1 190288 191280 R NADH dehydrogenase I subunit F complement(190288..191280) Helicobacter acinonychis str. Sheeba 4176452 YP_664069.1 CDS nuoE NC_008229.1 191277 191507 R NADH dehydrogenase I subunit E complement(191277..191507) Helicobacter acinonychis str. Sheeba 4177456 YP_664070.1 CDS nuoD NC_008229.1 191504 192733 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D complement(191504..192733) Helicobacter acinonychis str. Sheeba 4177455 YP_664071.1 CDS nuoC NC_008229.1 192735 193532 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit C complement(192735..193532) Helicobacter acinonychis str. Sheeba 4177454 YP_664072.1 CDS nuoB NC_008229.1 193532 194011 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(193532..194011) Helicobacter acinonychis str. Sheeba 4177453 YP_664073.1 CDS nuoA NC_008229.1 194011 194412 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit A complement(194011..194412) Helicobacter acinonychis str. Sheeba 4177452 YP_664074.1 CDS cobT NC_008229.1 194780 195469 R (O25849) NAD-dependent deacetylase (EC 3.5.1.-) (Regulatory protein SIR2 homolog); High confidence in function and specificity; nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphor complement(194780..195469) Helicobacter acinonychis str. Sheeba 4176890 YP_664075.1 CDS Hac_0227 NC_008229.1 195469 195921 R Function unclear; hypothetical protein complement(195469..195921) Helicobacter acinonychis str. Sheeba 4176308 YP_664076.1 CDS pyrE NC_008229.1 195911 196516 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(195911..196516) Helicobacter acinonychis str. Sheeba 4177753 YP_664077.1 CDS frr NC_008229.1 196520 197077 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(196520..197077) Helicobacter acinonychis str. Sheeba 4176524 YP_664078.1 CDS secG NC_008229.1 197077 197640 R (O25847) Protein-export membrane protein secG; High confidence in function and specificity; preprotein translocase subunit SecG complement(197077..197640) Helicobacter acinonychis str. Sheeba 4177171 YP_664079.1 CDS bioC NC_008229.1 197757 198482 D (Q9RX93) Trans-aconitate 2-methyltransferase (EC 2.1.1.144); High confidence in function and specificity; biotin synthesis protein BioC 197757..198482 Helicobacter acinonychis str. Sheeba 4177116 YP_664080.1 CDS trpS NC_008229.1 198540 199532 D catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 198540..199532 Helicobacter acinonychis str. Sheeba 4176669 YP_664081.1 CDS oppA fragment 1 NC_008229.1 199533 199994 D (P33913) Hypothetical protein yejA precursor; High confidence in function and specificity; peptide ABC transporter periplasmic protein 199533..199994 Helicobacter acinonychis str. Sheeba 4176447 YP_664082.1 CDS oppA fragment 2 NC_008229.1 199991 200452 D (P55691) Hypothetical protein Y4WM precursor; High confidence in function and specificity; peptide ABC transporter periplasmic protein 199991..200452 Helicobacter acinonychis str. Sheeba 4176448 YP_664083.1 CDS oppA fragment 3 NC_008229.1 200430 200654 D (P33913) Hypothetical protein yejA precursor; High confidence in function and specificity; peptide ABC transporter system,periplasmic component fragment 3 200430..200654 Helicobacter acinonychis str. Sheeba 4176449 YP_664084.1 CDS oppA fragment 4 NC_008229.1 200680 200775 D Function unclear; peptide ABC transporter system,periplasmic component fragment 4 200680..200775 Helicobacter acinonychis str. Sheeba 4176450 YP_664085.1 CDS oppA fragment 5 NC_008229.1 200848 201120 D (P55691) Hypothetical protein Y4WM precursor; High confidence in function and specificity; peptide ABC transporter system,periplasmic component fragment 5 200848..201120 Helicobacter acinonychis str. Sheeba 4176451 YP_664086.1 CDS oppA fragment 6 NC_008229.1 201133 201258 D Function unclear; peptide ABC transporter system,periplasmic component fragment 6 201133..201258 Helicobacter acinonychis str. Sheeba 4177319 YP_664087.1 CDS oppB fragment 1 NC_008229.1 201336 201455 D Function unclear; peptide ABC transporter permease 201336..201455 Helicobacter acinonychis str. Sheeba 4177320 YP_664088.1 CDS oppB fragment 2 NC_008229.1 201476 201709 D (P33914) Hypothetical ABC transporter permease yejB; High confidence in function and specificity; peptide ABC transporter permease 201476..201709 Helicobacter acinonychis str. Sheeba 4177321 YP_664089.1 CDS oppB fragment 3 NC_008229.1 201712 202305 D (P33914) Hypothetical ABC transporter permease yejB; High confidence in function and specificity; peptide ABC transporter permease 201712..202305 Helicobacter acinonychis str. Sheeba 4177322 YP_664090.1 CDS Hac_0243 NC_008229.1 202589 203164 D hypothetical protein 202589..203164 Helicobacter acinonychis str. Sheeba 4176309 YP_664091.1 CDS aroE NC_008229.1 203172 203963 D AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 203172..203963 Helicobacter acinonychis str. Sheeba 4176936 YP_664092.1 CDS vacB NC_008229.1 203963 205897 D (P56123) Ribonuclease R (EC 3.1.-.-) (RNase R) (VacB protein homolog); High confidence in function and specificity; ribonuclease R 203963..205897 Helicobacter acinonychis str. Sheeba 4176629 YP_664093.1 CDS dnaX NC_008229.1 205902 206909 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 205902..206909 Helicobacter acinonychis str. Sheeba 4177138 YP_664094.1 CDS rpsF NC_008229.1 207262 207690 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 207262..207690 Helicobacter acinonychis str. Sheeba 4177146 YP_664095.1 CDS ssb NC_008229.1 207706 208251 D binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 207706..208251 Helicobacter acinonychis str. Sheeba 4177463 YP_664096.1 CDS rpsR NC_008229.1 208275 208532 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 208275..208532 Helicobacter acinonychis str. Sheeba 4177157 YP_664097.1 CDS flgG NC_008229.1 208943 209731 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 208943..209731 Helicobacter acinonychis str. Sheeba 4177246 YP_664098.1 CDS Hac_0253 NC_008229.1 209728 210258 R hypothetical protein complement(209728..210258) Helicobacter acinonychis str. Sheeba 4176310 YP_664099.1 CDS nusB NC_008229.1 210313 210729 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(210313..210729) Helicobacter acinonychis str. Sheeba 4176463 YP_664100.1 CDS ribH NC_008229.1 210731 211201 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(210731..211201) Helicobacter acinonychis str. Sheeba 4177090 YP_664101.1 CDS kdsA NC_008229.1 211212 212042 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(211212..212042) Helicobacter acinonychis str. Sheeba 4176132 YP_664102.1 CDS cynT NC_008229.1 212029 212694 R (Q9ZN54) Carbonic anhydrase (EC 4.2.1.1); High confidence in function and specificity; hypothetical protein complement(212029..212694) Helicobacter acinonychis str. Sheeba 4176394 YP_664103.1 CDS pyrF NC_008229.1 212815 213498 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 212815..213498 Helicobacter acinonychis str. Sheeba 4177754 YP_664104.1 CDS panC NC_008229.1 213501 214331 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 213501..214331 Helicobacter acinonychis str. Sheeba 4177337 YP_664105.1 CDS Hac_0260 NC_008229.1 215110 215457 R High confidence in function and specificity; hypothetical protein complement(215110..215457) Helicobacter acinonychis str. Sheeba 4176311 YP_664106.1 CDS Hac_0261 NC_008229.1 215451 216137 R High confidence in function and specificity; hypothetical protein complement(215451..216137) Helicobacter acinonychis str. Sheeba 4176312 YP_664107.1 CDS dnaJ NC_008229.1 216137 217252 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(216137..217252) Helicobacter acinonychis str. Sheeba 4177134 YP_664108.1 CDS Hac_0263 NC_008229.1 217376 218524 D hypothetical protein 217376..218524 Helicobacter acinonychis str. Sheeba 4176313 YP_664109.1 CDS mnmA NC_008229.1 218571 219599 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(218571..219599) Helicobacter acinonychis str. Sheeba 4177490 YP_664110.1 CDS Hac_0265 NC_008229.1 219744 220505 D Function unclear; hypothetical protein 219744..220505 Helicobacter acinonychis str. Sheeba 4176314 YP_664111.1 CDS nadD NC_008229.1 220502 221002 R High confidence in function and specificity; nicotinate-nucleotide adenylyltransferase complement(220502..221002) Helicobacter acinonychis str. Sheeba 4177664 YP_664112.1 CDS Hac_0267 NC_008229.1 221012 221458 R Inhibits transcription at high concentrations of nickel; nickel responsive regulator complement(221012..221458) Helicobacter acinonychis str. Sheeba 4176315 YP_664113.1 CDS exbB NC_008229.1 221739 222179 D (Q9ZJP6) Biopolymer transport exbB protein; High confidence in function and specificity; biopolymer transport protein 221739..222179 Helicobacter acinonychis str. Sheeba 4177401 YP_664114.1 CDS exbD NC_008229.1 222176 222565 D (Q9ZJP5) Biopolymer transport exbD protein; High confidence in function and specificity; hypothetical protein 222176..222565 Helicobacter acinonychis str. Sheeba 4177404 YP_664115.1 CDS tonB NC_008229.1 222531 223400 D (O07650) TonB protein; High confidence in function and specificity; siderophore-mediated iron transport protein 222531..223400 Helicobacter acinonychis str. Sheeba 4177487 YP_664116.1 CDS Hac_0272 NC_008229.1 223638 224366 R High confidence in function and specificity; hypothetical protein complement(223638..224366) Helicobacter acinonychis str. Sheeba 4176316 YP_664117.1 CDS corA NC_008229.1 224373 225329 R (P27841) Magnesium and cobalt transport protein corA; High confidence in function and specificity; magnesium and cobalt transport protein complement(224373..225329) Helicobacter acinonychis str. Sheeba 4176899 YP_664118.1 CDS pgk NC_008229.1 225345 226553 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(225345..226553) Helicobacter acinonychis str. Sheeba 4176773 YP_664119.1 CDS gap NC_008229.1 226568 227560 R (O34425) Glyceraldehyde 3-phosphate dehydrogenase 2 (EC 1.2.1.59) (GAPDH) (NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase); High confidence in function and specificity; glyceraldehyde 3-phosphate dehydrogenase complement(226568..227560) Helicobacter acinonychis str. Sheeba 4177022 YP_664120.1 CDS ung NC_008229.1 227646 228347 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(227646..228347) Helicobacter acinonychis str. Sheeba 4176683 YP_664121.1 CDS plsC NC_008229.1 228334 229026 R (O25903) 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) (1-AGP acyltransferase) (1-AGPAT) (Lysophosphatidic acid acyltransferase) (LPAAT); High confidence in function and specificity; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(228334..229026) Helicobacter acinonychis str. Sheeba 4176783 YP_664122.1 CDS Hac_0278 NC_008229.1 229040 230200 R hypothetical protein complement(229040..230200) Helicobacter acinonychis str. Sheeba 4177718 YP_664123.1 CDS ctpA NC_008229.1 230225 231586 R (Q44879) Carboxy-terminal processing protease precursor (EC 3.4.21.102) (C-terminal processing protease); High confidence in function and specificity; carboxy-terminal processing protease complement(230225..231586) Helicobacter acinonychis str. Sheeba 4176906 YP_664124.1 CDS gcp NC_008229.1 231805 232833 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 231805..232833 Helicobacter acinonychis str. Sheeba 4177759 YP_664125.1 CDS dcm NC_008229.1 233955 235211 R (P09795) Modification methylase SinI (EC 2.1.1.37) (Cytosine-specific methyltransferase SinI) (M.SinI); hypothetical protein; site-specific DNA-methyltransferase complement(233955..235211) Helicobacter acinonychis str. Sheeba 4176408 YP_664126.1 CDS Hac_0284 NC_008229.1 235201 236301 R hypothetical protein complement(235201..236301) Helicobacter acinonychis str. Sheeba 4177719 YP_664127.1 CDS tsf NC_008229.1 236361 237428 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(236361..237428) Helicobacter acinonychis str. Sheeba 4176675 YP_664128.1 CDS rpsB NC_008229.1 237482 238222 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(237482..238222) Helicobacter acinonychis str. Sheeba 4177142 YP_664129.1 CDS pcrA NC_008229.1 238474 241374 D (Q89AB3) Exodeoxyribonuclease V beta chain (EC 3.1.11.5); Function unclear; recombination protein RecB 238474..241374 Helicobacter acinonychis str. Sheeba 4176741 YP_664130.1 CDS nhaA NC_008229.1 241398 242714 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 241398..242714 Helicobacter acinonychis str. Sheeba 4177444 YP_664131.1 CDS yajC NC_008229.1 242763 243053 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 242763..243053 Helicobacter acinonychis str. Sheeba 4176644 YP_664132.1 CDS secD NC_008229.1 243054 244634 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 243054..244634 Helicobacter acinonychis str. Sheeba 4177168 YP_664133.1 CDS secF NC_008229.1 244643 245614 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 244643..245614 Helicobacter acinonychis str. Sheeba 4177170 YP_664134.1 CDS Hac_0292 NC_008229.1 245624 245962 D hypothetical protein 245624..245962 Helicobacter acinonychis str. Sheeba 4177720 YP_664135.1 CDS leuS NC_008229.1 245972 248392 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 245972..248392 Helicobacter acinonychis str. Sheeba 4177613 YP_664136.1 CDS Hac_0294 NC_008229.1 248389 248907 D hypothetical protein 248389..248907 Helicobacter acinonychis str. Sheeba 4177721 YP_664137.1 CDS folC NC_008229.1 248912 250072 D (P43775) Folylpolyglutamate synthase (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS); High confidence in function and specificity; folylpolyglutamate synthase / dihydrofolate synthase 248912..250072 Helicobacter acinonychis str. Sheeba 4177509 YP_664138.1 CDS tagE NC_008229.1 250072 250998 D Function unclear; toxR-activated gene 250072..250998 Helicobacter acinonychis str. Sheeba 4177465 YP_664139.1 CDS tagE NC_008229.1 251007 251942 D High confidence in function and specificity; toxR-activated gene 251007..251942 Helicobacter acinonychis str. Sheeba 4177466 YP_664140.1 CDS Hac_0298 NC_008229.1 251861 252268 D Function unclear; hypothetical protein 251861..252268 Helicobacter acinonychis str. Sheeba 4177722 YP_664141.1 CDS mfd NC_008229.1 252268 255282 D (O26066) Transcription-repair coupling factor (TRCF); High confidence in function and specificity; transcription-repair coupling factor 252268..255282 Helicobacter acinonychis str. Sheeba 4176764 YP_664142.1 CDS fbcF NC_008229.1 255396 255899 D (P51130) Ubiquinol-cytochrome c reductase iron-sulfur subunit (EC 1.10.2.2) (Rieske iron-sulfur protein) (RISP); Function unclear; cytochrome b6-F complex iron-sulfur subunit 255396..255899 Helicobacter acinonychis str. Sheeba 4177416 YP_664143.1 CDS fbcB NC_008229.1 255911 257149 D (P51131) Cytochrome b/c1 [Includes: Cytochrome b; Cytochrome c1]; High confidence in function and specificity; ubiquinol cytochrome c oxidoreductase,cytochrome b subunit 255911..257149 Helicobacter acinonychis str. Sheeba 4177414 YP_664144.1 CDS fbcC NC_008229.1 257146 258003 D Function unclear; ubiquinol-cytochrome c reductase cytochrome c1 subunit 257146..258003 Helicobacter acinonychis str. Sheeba 4177415 YP_664145.1 CDS cysE NC_008229.1 258252 258803 D (P71405) Serine acetyltransferase (EC 2.3.1.30) (SAT); High confidence in function and specificity; hypothetical protein 258252..258803 Helicobacter acinonychis str. Sheeba 4176395 YP_664146.1 CDS Hac_0305 NC_008229.1 259057 259575 D Region start changed from 259192 to 259057 (135 bases); ulcer-associated gene restriction endonuclease 259057..259575 Helicobacter acinonychis str. Sheeba 4177723 YP_664147.1 CDS hpyIM NC_008229.1 259584 260573 D (P24582) Modification methylase NlaIII (EC 2.1.1.72) (CATG-specific methyltransferase HpyIM) (M.HpyI); High confidence in function and specificity; adenine-specific methyltransferase 259584..260573 Helicobacter acinonychis str. Sheeba 4176884 YP_664148.1 CDS kdsB NC_008229.1 260839 261570 R CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase complement(260839..261570) Helicobacter acinonychis str. Sheeba 4176133 YP_664149.1 CDS Hac_0308 NC_008229.1 261670 262458 D protein-disulphide isomerase; Function unclear; hypothetical protein 261670..262458 Helicobacter acinonychis str. Sheeba 4177724 YP_664150.1 CDS Hac_0309 NC_008229.1 262474 263121 D High confidence in function and specificity; hypothetical protein 262474..263121 Helicobacter acinonychis str. Sheeba 4177725 YP_664151.1 CDS Hac_0310 NC_008229.1 263136 264308 D High confidence in function and specificity; hypothetical protein 263136..264308 Helicobacter acinonychis str. Sheeba 4177726 YP_664152.1 CDS Hac_0311 NC_008229.1 264308 264838 D integral membrane protein; hypothetical protein; hypothetical protein 264308..264838 Helicobacter acinonychis str. Sheeba 4177727 YP_664153.1 CDS sdaA NC_008229.1 264924 266291 R High confidence in function and specificity; hypothetical protein complement(264924..266291) Helicobacter acinonychis str. Sheeba 4177165 YP_664154.1 CDS sdaC NC_008229.1 266291 267532 R (P44615) Serine transporter; High confidence in function and specificity; serine transporter complement(266291..267532) Helicobacter acinonychis str. Sheeba 4177166 YP_664155.1 CDS aroAII NC_008229.1 267718 269067 D (P21357) AroAII Phospho-2-dehydro-3-deoxyheptonate aldolase 1 chloroplast precursor (EC 2.5.1.54); High confidence in function and specificity; phospho-2-dehydro-3-deoxyheptonate aldolase 267718..269067 Helicobacter acinonychis str. Sheeba 4176933 YP_664156.1 CDS Hac_0315 NC_008229.1 269343 269504 R hypothetical protein complement(269343..269504) Helicobacter acinonychis str. Sheeba 4177728 YP_664157.1 CDS bcp NC_008229.1 269708 270166 R (Q9ZMU4) Bacterioferritin comigratory protein homolog; High confidence in function and specificity; bacterioferritin comigratory protein complement(269708..270166) Helicobacter acinonychis str. Sheeba 4177112 YP_664158.1 CDS Hac_0318 NC_008229.1 270176 270811 R (P77433) Hypothetical protein ykgG; Specificity unclear; hypothetical protein complement(270176..270811) Helicobacter acinonychis str. Sheeba 4177729 YP_664159.1 CDS Hac_0319 NC_008229.1 270804 272249 R (P77536) electron transport protein (ykgF); High confidence in function and specificity; iron-sulfur electron transport protein complement(270804..272249) Helicobacter acinonychis str. Sheeba 4177730 YP_664160.1 CDS Hac_0320 NC_008229.1 272273 273001 R Specificity unclear; Fe-S oxidoreductase complement(272273..273001) Helicobacter acinonychis str. Sheeba 4177731 YP_664161.1 CDS lldP NC_008229.1 273222 274868 D High confidence in function and specificity; hypothetical protein 273222..274868 Helicobacter acinonychis str. Sheeba 4177616 YP_664162.1 CDS Hac_0322 NC_008229.1 274819 275109 R hypothetical protein complement(274819..275109) Helicobacter acinonychis str. Sheeba 4177732 YP_664163.1 CDS mutY NC_008229.1 275114 275983 R High confidence in function and specificity; DNA glycosylase MutY complement(275114..275983) Helicobacter acinonychis str. Sheeba 4177659 YP_664164.1 CDS citT NC_008229.1 276101 277549 R (P77405) Citrate carrier (Citrate transporter) (Citrate/succinate antiporter); High confidence in function and specificity; citrate carrier complement(276101..277549) Helicobacter acinonychis str. Sheeba 4176605 YP_664165.1 CDS fixN NC_008229.1 277745 279232 D CcoN; FixN; cbb3-type cytochrome c oxidase subunit I 277745..279232 Helicobacter acinonychis str. Sheeba 4176820 YP_664166.1 CDS fixO NC_008229.1 279237 279926 D CcoO; FixO; cbb3-type cytochrome c oxidase subunit II 279237..279926 Helicobacter acinonychis str. Sheeba 4176821 YP_664167.1 CDS fixQ NC_008229.1 279937 280155 D Family membership; cb-type cytochrome c oxidase subunit IV 279937..280155 Helicobacter acinonychis str. Sheeba 4176823 YP_664168.1 CDS fixP NC_008229.1 280157 281035 D (Q04441) Cytochrome c oxidase polypeptide II precursor (EC 1.9.3.1) (Cytochrome aa3 subunit 2) (Oxidase aa(3) subunit 2); Function unclear; cb-type cytochrome c oxidase subunit III 280157..281035 Helicobacter acinonychis str. Sheeba 4176822 YP_664169.1 CDS Hac_0329 NC_008229.1 281046 281252 D hypothetical protein 281046..281252 Helicobacter acinonychis str. Sheeba 4177733 YP_664170.1 CDS Hac_0330 NC_008229.1 281353 281940 D hypothetical protein 281353..281940 Helicobacter acinonychis str. Sheeba 4177734 YP_664171.1 CDS Hac_0331 NC_008229.1 281953 282540 D hypothetical protein 281953..282540 Helicobacter acinonychis str. Sheeba 4177735 YP_664172.1 CDS Hac_0334 NC_008229.1 282892 283659 D hypothetical protein 282892..283659 Helicobacter acinonychis str. Sheeba 4177736 YP_664173.1 CDS Hac_0335 NC_008229.1 283656 284519 R Function unclear; hypothetical protein complement(283656..284519) Helicobacter acinonychis str. Sheeba 4176237 YP_664174.1 CDS recA NC_008229.1 284618 285661 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 284618..285661 Helicobacter acinonychis str. Sheeba 4177068 YP_664175.1 CDS eno NC_008229.1 285672 286952 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 285672..286952 Helicobacter acinonychis str. Sheeba 4177398 YP_664176.1 CDS Hac_0338 NC_008229.1 286945 287220 D hypothetical protein 286945..287220 Helicobacter acinonychis str. Sheeba 4176238 YP_664177.1 CDS Hac_0339 NC_008229.1 287232 287828 D hypothetical protein 287232..287828 Helicobacter acinonychis str. Sheeba 4176239 YP_664178.1 CDS aroK NC_008229.1 287833 288321 D catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 287833..288321 Helicobacter acinonychis str. Sheeba 4176937 YP_664179.1 CDS Hac_0341 NC_008229.1 288342 289298 D hypothetical protein 288342..289298 Helicobacter acinonychis str. Sheeba 4176240 YP_664180.1 CDS rfaJ NC_008229.1 289295 290398 R High confidence in function and specificity; lipopolysaccharide 1,2-glucosyltransferase complement(289295..290398) Helicobacter acinonychis str. Sheeba 4177081 YP_664181.1 CDS Hac_0343 NC_008229.1 290558 291454 D (Q9ZMS0) beta-lactamase hcpD precursor (EC 3.5.2.6) (Cysteine-rich protein D) (PBP 4) (Penicillin-binding protein 4); Specificity unclear; hypothetical protein 290558..291454 Helicobacter acinonychis str. Sheeba 4176241 YP_664182.1 CDS Hac_0344 NC_008229.1 292119 292841 R (Q9ZMR9) Hypothetical UPF0082 protein JHP0149; High confidence in function and specificity; hypothetical protein complement(292119..292841) Helicobacter acinonychis str. Sheeba 4176242 YP_664183.1 CDS hemB NC_008229.1 292842 293813 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(292842..293813) Helicobacter acinonychis str. Sheeba 4177422 YP_664184.1 CDS Hac_0346 NC_008229.1 293889 295163 R (Q44007) resembles Sensor proteins racS and czcS (EC 2.7.3.-); High confidence in function and specificity; two-component sensor histidine kinase complement(293889..295163) Helicobacter acinonychis str. Sheeba 4176243 YP_664185.1 CDS ompR NC_008229.1 295187 295864 R (P48259) Probable transcriptional regulator ycf27 (OmpR-like protein); High confidence in function and specificity; response regulator complement(295187..295864) Helicobacter acinonychis str. Sheeba 4176442 YP_664186.1 CDS Hac_0348 NC_008229.1 296277 296735 R hypothetical protein complement(296277..296735) Helicobacter acinonychis str. Sheeba 4176244 YP_664187.1 CDS Hac_0349 NC_008229.1 296726 296989 R hypothetical protein complement(296726..296989) Helicobacter acinonychis str. Sheeba 4176245 YP_664188.1 CDS prtC NC_008229.1 297030 298307 R (P56113) protease HP0169 precursor (EC 3.4.-.-); hypothetical protein; protease complement(297030..298307) Helicobacter acinonychis str. Sheeba 4176568 YP_664189.1 CDS Hac_0351 NC_008229.1 298310 299038 R (Q18823) Laminin-like protein C54D1.5 precursor; hypothetical protein; hypothetical protein complement(298310..299038) Helicobacter acinonychis str. Sheeba 4176246 YP_664190.1 CDS prfB NC_008229.1 299102 300193 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(299102..300193) Helicobacter acinonychis str. Sheeba 4176560 YP_664191.1 CDS fliR NC_008229.1 300254 301021 R FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR complement(300254..301021) Helicobacter acinonychis str. Sheeba 4177504 YP_664192.1 CDS Hac_0354 NC_008229.1 301015 301743 R hypothetical protein complement(301015..301743) Helicobacter acinonychis str. Sheeba 4176247 YP_664193.1 CDS Hac_0356 NC_008229.1 301924 302820 D peptidyl-prolyl cis-trans isomerase 301924..302820 Helicobacter acinonychis str. Sheeba 4176248 YP_664194.1 CDS fba NC_008229.1 302830 303753 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 302830..303753 Helicobacter acinonychis str. Sheeba 4177413 YP_664195.1 CDS efp NC_008229.1 303775 304338 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 303775..304338 Helicobacter acinonychis str. Sheeba 4176393 YP_664196.1 CDS Hac_0360 NC_008229.1 304795 305928 D DNA-cytosine methyltransferase 304795..305928 Helicobacter acinonychis str. Sheeba 4176249 YP_664197.1 CDS Hac_0361 NC_008229.1 305915 306685 D hypothetical protein 305915..306685 Helicobacter acinonychis str. Sheeba 4176250 YP_664198.1 CDS Hac_0362 NC_008229.1 306660 308003 D GTPase subunit of restriction endonuclease; hypothetical protein; type II restriction enzyme 306660..308003 Helicobacter acinonychis str. Sheeba 4176251 YP_664199.1 CDS Hac_0363 NC_008229.1 307996 309213 D type II restriction-modification system restriction subunit; hypothetical protein; hypothetical protein 307996..309213 Helicobacter acinonychis str. Sheeba 4176252 YP_664200.1 CDS Hac_0364 NC_008229.1 309299 310321 R hypothetical protein complement(309299..310321) Helicobacter acinonychis str. Sheeba 4176253 YP_664201.1 CDS Hac_0365 NC_008229.1 310324 310965 R ABC transporter ATP-binding protein complement(310324..310965) Helicobacter acinonychis str. Sheeba 4176254 YP_664202.1 CDS cute NC_008229.1 310962 312239 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(310962..312239) Helicobacter acinonychis str. Sheeba 4176907 YP_664203.1 CDS Hac_0367 NC_008229.1 312483 313181 D Uncharacterized membrane protein, required for colicin V production; hypothetical protein; hypothetical protein 312483..313181 Helicobacter acinonychis str. Sheeba 4176255 YP_664204.1 CDS lysS NC_008229.1 313191 314696 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 313191..314696 Helicobacter acinonychis str. Sheeba 4177630 YP_664205.1 CDS glyA NC_008229.1 314696 315946 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 314696..315946 Helicobacter acinonychis str. Sheeba 4177263 YP_664206.1 CDS Hac_0370 NC_008229.1 315957 316499 D hypothetical protein 315957..316499 Helicobacter acinonychis str. Sheeba 4176256 YP_664207.1 CDS Hac_0371 NC_008229.1 316521 317321 D conserved hypothetical protein; hypothetical protein 316521..317321 Helicobacter acinonychis str. Sheeba 4177515 YP_664208.1 CDS Hac_0372 NC_008229.1 317639 319765 D conserved hypothetical protein; hypothetical protein 317639..319765 Helicobacter acinonychis str. Sheeba 4177516 YP_664209.1 CDS Hac_0373 NC_008229.1 319821 320126 D conserved hypothetical protein; hypothetical protein 319821..320126 Helicobacter acinonychis str. Sheeba 4177517 YP_664210.1 CDS Hac_0374 NC_008229.1 320132 320401 D (O24989) Hypothetical protein HP0189(O24989) Hypothetical protein HP0189; specifity unclear; hypothetical protein 320132..320401 Helicobacter acinonychis str. Sheeba 4177518 YP_664211.1 CDS Hac_0375 NC_008229.1 320408 321916 R (Q9ZMP2) Hypothetical protein JHP0176(Q9ZMP2); Specificity unclear; phospholipase complement(320408..321916) Helicobacter acinonychis str. Sheeba 4177519 YP_664212.1 CDS frdB NC_008229.1 321937 322674 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(321937..322674) Helicobacter acinonychis str. Sheeba 4176519 YP_664213.1 CDS frdA NC_008229.1 322667 324811 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(322667..324811) Helicobacter acinonychis str. Sheeba 4176518 YP_664214.1 CDS frdC NC_008229.1 324821 325588 R part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; fumarate reductase cytochrome b-556 subunit complement(324821..325588) Helicobacter acinonychis str. Sheeba 4176520 YP_664215.1 CDS tpiA NC_008229.1 325802 326506 D tim; Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 325802..326506 Helicobacter acinonychis str. Sheeba 4177480 YP_664216.1 CDS fabI NC_008229.1 326516 327343 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 326516..327343 Helicobacter acinonychis str. Sheeba 4177411 YP_664217.1 CDS lpxD NC_008229.1 327354 328364 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 327354..328364 Helicobacter acinonychis str. Sheeba 4177623 YP_664218.1 CDS metK NC_008229.1 328425 329582 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 328425..329582 Helicobacter acinonychis str. Sheeba 4176762 YP_664219.1 CDS ndk NC_008229.1 329649 330062 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 329649..330062 Helicobacter acinonychis str. Sheeba 4177438 YP_664220.1 CDS Hac_0384 NC_008229.1 330087 330443 D conserved hypothetical protein; hypothetical protein 330087..330443 Helicobacter acinonychis str. Sheeba 4177520 YP_664221.1 CDS rpmF NC_008229.1 330459 330605 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 330459..330605 Helicobacter acinonychis str. Sheeba 4176860 YP_664222.1 CDS plsX NC_008229.1 330668 331687 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 330668..331687 Helicobacter acinonychis str. Sheeba 4176784 YP_664223.1 CDS fabH NC_008229.1 331712 332707 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 331712..332707 Helicobacter acinonychis str. Sheeba 4177410 YP_664224.1 CDS Hac_0388 NC_008229.1 332730 333032 D conserved hypothetical protein; hypothetical protein 332730..333032 Helicobacter acinonychis str. Sheeba 4177521 YP_664225.1 CDS fragment 2 NC_008229.1 333304 333519 R hypothetical protein complement(333304..333519) Helicobacter acinonychis str. Sheeba 4177224 YP_664226.1 CDS fragment 1 NC_008229.1 333714 335117 R hypothetical protein complement(333714..335117) Helicobacter acinonychis str. Sheeba 4176342 YP_664227.1 CDS cah NC_008229.1 335560 336303 R (O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase)(O52538) Carbonic anhydrase precursor (EC 4.2.1.1) (Carbonate dehydratase); High confidence in function and specificity; hypothetical protein complement(335560..336303) Helicobacter acinonychis str. Sheeba 4176589 YP_664228.1 CDS Hac_0393 NC_008229.1 336529 337704 D Region start changed from 336580 to 336529 (51 bases); sugar efflux transporter 336529..337704 Helicobacter acinonychis str. Sheeba 4177522 YP_664229.1 CDS Hac_0394 NC_008229.1 337807 339192 D hypothetical protein 337807..339192 Helicobacter acinonychis str. Sheeba 4177523 YP_664230.1 CDS napA NC_008229.1 339217 340368 D (P40309) K(+)/H(+) antiporter, NA+/H+ antiporter (napA) [Helicobacter pylori 26695]; hypothetical protein; Na+/H+ antiporter 339217..340368 Helicobacter acinonychis str. Sheeba 4177666 YP_664231.1 CDS Hac_0396 NC_008229.1 340376 341137 R hypothetical protein complement(340376..341137) Helicobacter acinonychis str. Sheeba 4177524 YP_664232.1 CDS Hac_0397 NC_008229.1 341156 342544 R (P77726) Hypothetical transport protein; hypothetical protein; major facilitator family transporter complement(341156..342544) Helicobacter acinonychis str. Sheeba 4177525 YP_664233.1 CDS nupC NC_008229.1 342832 344088 D (Q62773) Sodium/nucleoside cotransporter 2 (Na(+)/nucleoside cotransporter 2) (Sodium-coupled nucleoside transporter 2) (Concentrative nucleoside transporter 2) (CNT 2) (Sodium/purine nucleoside co-transporter) (SPNT) (RCNT2); hypothetical protein; pyrimidine nucleoside transport protein 342832..344088 Helicobacter acinonychis str. Sheeba 4176461 YP_664234.1 CDS deoB NC_008229.1 344100 345341 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 344100..345341 Helicobacter acinonychis str. Sheeba 4177125 YP_664235.1 CDS deoD NC_008229.1 345338 346039 D (P56463) Purine nucleoside phosphorylase (EC 2.4.2.1) (Inosine phosphorylase) (PNP); High confidence in function and specificity; hypothetical protein 345338..346039 Helicobacter acinonychis str. Sheeba 4177126 YP_664236.1 CDS Hac_0401 NC_008229.1 346488 347795 D transmembrane transport protein; Specificity unclear; hypothetical protein 346488..347795 Helicobacter acinonychis str. Sheeba 4177526 YP_664237.1 CDS fucP NC_008229.1 347923 349146 D High confidence in function and specificity; glucose/galactose transporter 347923..349146 Helicobacter acinonychis str. Sheeba 4177010 YP_664238.1 CDS Hac_0404 NC_008229.1 349425 349985 R hypothetical protein complement(349425..349985) Helicobacter acinonychis str. Sheeba 4177527 YP_664239.1 CDS glnH NC_008229.1 350086 350919 R (P27676) Glutamine-binding protein precursor (GlnBP); High confidence in function and specificity; polar amino acid transport system substrate-binding protein complement(350086..350919) Helicobacter acinonychis str. Sheeba 4177770 YP_664240.1 CDS glnQ NC_008229.1 350969 351715 R glutamine transport system permease; High confidence in function and specificity; polar amino acid transport system ATP-binding protein complement(350969..351715) Helicobacter acinonychis str. Sheeba 4177773 YP_664241.1 CDS glnP NC_008229.1 351717 352388 R glutamine transport system permease; Function unclear; polar amino acid transport system permease complement(351717..352388) Helicobacter acinonychis str. Sheeba 4177771 YP_664242.1 CDS glnP NC_008229.1 352390 353022 R glutamine ABC transporter permease (glnP); Function unclear; polar amino acid transport system permease complement(352390..353022) Helicobacter acinonychis str. Sheeba 4177772 YP_664243.1 CDS cstA NC_008229.1 353235 355298 D (Q9ZK47) Carbon starvation protein A homolog; High confidence in function and specificity; carbon starvation protein A 353235..355298 Helicobacter acinonychis str. Sheeba 4176905 YP_664244.1 CDS hofH NC_008229.1 355848 357170 R outer membrane protein,no omp family protein; hypothetical protein; hof family outer membrane protein complement(355848..357170) Helicobacter acinonychis str. Sheeba 4176872 YP_664245.1 CDS nrdF NC_008229.1 357791 358816 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 357791..358816 Helicobacter acinonychis str. Sheeba 4177448 YP_664246.1 CDS pcm NC_008229.1 358826 359455 D catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 358826..359455 Helicobacter acinonychis str. Sheeba 4176740 YP_664247.1 CDS Hac_0413 NC_008229.1 359442 360512 D Predicted permease; Function unclear; hypothetical protein 359442..360512 Helicobacter acinonychis str. Sheeba 4177528 YP_664248.1 CDS truA NC_008229.1 360514 361242 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 360514..361242 Helicobacter acinonychis str. Sheeba 4176670 YP_664249.1 CDS galE NC_008229.1 361236 362270 R High confidence in function and specificity; hypothetical protein complement(361236..362270) Helicobacter acinonychis str. Sheeba 4177020 YP_664250.1 CDS fragment NC_008229.1 362704 362952 R High confidence in function and specificity; thiol peroxidase complement(362704..362952) Helicobacter acinonychis str. Sheeba 4177514 YP_664251.1 CDS sodB NC_008229.1 363422 364069 D (Q9ZKE6) Superoxide dismutase [Fe] (EC 1.15.1.1); High confidence in function and specificity; hypothetical protein 363422..364069 Helicobacter acinonychis str. Sheeba 4177459 YP_664252.1 CDS Hac_0420 NC_008229.1 364123 364842 D TIGR00740: methyltransferase, Specificity unclear; hypothetical protein 364123..364842 Helicobacter acinonychis str. Sheeba 4177529 YP_664253.1 CDS priA NC_008229.1 364848 366707 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(364848..366707) Helicobacter acinonychis str. Sheeba 4176561 YP_664254.1 CDS Hac_0422 NC_008229.1 366692 366928 R (O25148) Hypothetical protein HP0386/JHP0995; High confidence in function and specificity; hypothetical protein complement(366692..366928) Helicobacter acinonychis str. Sheeba 4177530 YP_664255.1 CDS Hac_0423 NC_008229.1 366941 367168 R hypothetical protein complement(366941..367168) Helicobacter acinonychis str. Sheeba 4177531 YP_664256.1 CDS Hac_0424 NC_008229.1 367325 369679 D hypothetical protein 367325..369679 Helicobacter acinonychis str. Sheeba 4177532 YP_664257.1 CDS Hac_0425 NC_008229.1 369745 370035 D hypothetical protein 369745..370035 Helicobacter acinonychis str. Sheeba 4177533 YP_664258.1 CDS uvrB NC_008229.1 370104 372080 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 370104..372080 Helicobacter acinonychis str. Sheeba 4176695 YP_664259.1 CDS omp3 NC_008229.1 372077 372910 R outer membrane protein 3 complement(372077..372910) Helicobacter acinonychis str. Sheeba 4176581 YP_664260.1 CDS purB NC_008229.1 373021 374343 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(373021..374343) Helicobacter acinonychis str. Sheeba 4177743 YP_664261.1 CDS porB NC_008229.1 374436 375380 R (Q57714) Pyruvate synthase subunit porB (EC 1.2.7.1) (Pyruvate oxidoreductase beta chain) (POR) (Pyruvic-ferredoxin oxidoreductase beta subunit); High confidence in function and specificity; pyruvate ferredoxin oxidoreductase subunit beta complement(374436..375380) Helicobacter acinonychis str. Sheeba 4176790 YP_664262.1 CDS porA NC_008229.1 375393 376616 R (O05651) Pyruvate synthase subunit porA (EC 1.2.7.1) (Pyruvate oxidoreductase alpha chain) (POR) (Pyruvic-ferredoxin oxidoreductase alpha subunit); High confidence in function and specificity; pyruvate flavodoxin oxidoreductase subunit alpha complement(375393..376616) Helicobacter acinonychis str. Sheeba 4176789 YP_664263.1 CDS porD NC_008229.1 376626 377018 R (Q56316) Pyruvate synthase subunit porD (EC 1.2.7.1) (Pyruvate oxidoreductase delta chain) (POR) (Pyruvic-ferredoxin oxidoreductase delta subunit); Function unclear; pyruvate flavodoxin oxidoreductase subunit delta complement(376626..377018) Helicobacter acinonychis str. Sheeba 4176550 YP_664264.1 CDS porG NC_008229.1 377034 377594 R (Q9UYY9) Pyruvate/ketoisovalerate oxidoreductases common gamma subunit [Includes: Pyruvate synthase subunit porC (EC 1.2.7.1) (Pyruvate oxidoreductase gamma chain) (POR) (Pyruvic-ferredoxin oxidoreductase gamma subunit); Ketoisovalerate oxidor; High confidence in function and specificity; pyruvate flavodoxin oxidoreductase subunit gamma complement(377034..377594) Helicobacter acinonychis str. Sheeba 4176551 YP_664265.1 CDS omp4 NC_008229.1 377858 378511 D outer membrane protein 4 377858..378511 Helicobacter acinonychis str. Sheeba 4176433 YP_664266.1 CDS Hac_0435 NC_008229.1 378514 379824 R hypothetical protein complement(378514..379824) Helicobacter acinonychis str. Sheeba 4176140 YP_664267.1 CDS Hac_0436 NC_008229.1 380002 381258 D (P27128) Lipopolysaccharide 13-galactosyltransferase (EC 2.4.1.44) (Lipopolysaccharide 3-alpha-galactosyltransferase); Function unclear; lipopolysaccharide biosynthesis protein 380002..381258 Helicobacter acinonychis str. Sheeba 4176141 YP_664268.1 CDS adhA NC_008229.1 381271 382323 R High confidence in function and specificity; NADP-dependent alcohol dehydrogenase complement(381271..382323) Helicobacter acinonychis str. Sheeba 4177700 YP_664269.1 CDS glk NC_008229.1 382630 383640 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(382630..383640) Helicobacter acinonychis str. Sheeba 4177766 YP_664270.1 CDS pgl NC_008229.1 383627 384310 R High confidence in function and specificity; 6-phosphogluconolactonase complement(383627..384310) Helicobacter acinonychis str. Sheeba 4176774 YP_664271.1 CDS Hac_0441 NC_008229.1 384321 385598 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(384321..385598) Helicobacter acinonychis str. Sheeba 4176142 YP_664272.1 CDS edd NC_008229.1 385661 387487 D catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 385661..387487 Helicobacter acinonychis str. Sheeba 4176392 YP_664273.1 CDS eda NC_008229.1 387498 388142 D (P38448) KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) (2-keto-4-hydroxyglutarate aldolase) (KHG-aldolase); 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) (Phospho-2-dehydro-3-deoxygluconate aldolase); High confidence in function and specificity; 2-dehydro-3-deoxyphosphogluconate aldolase 387498..388142 Helicobacter acinonychis str. Sheeba 4176391 YP_664274.1 CDS Hac_0444 NC_008229.1 388235 389110 D (Q9ZKB5) beta-lactamase hcpC precursor (EC 3.5.2.6) (Cysteine-rich protein C); Specificity unclear; secreted protein 388235..389110 Helicobacter acinonychis str. Sheeba 4176143 YP_664275.1 CDS Hac_0445 NC_008229.1 389213 390748 R outer membrane protein complement(389213..390748) Helicobacter acinonychis str. Sheeba 4176144 YP_664276.1 CDS Hac_0446 NC_008229.1 390884 391996 D Specificity unclear; hypothetical protein 390884..391996 Helicobacter acinonychis str. Sheeba 4176145 YP_664277.1 CDS ureB NC_008229.1 392063 393772 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit beta complement(392063..393772) Helicobacter acinonychis str. Sheeba 4176687 YP_664278.1 CDS ureAB NC_008229.1 393783 394466 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit alpha complement(393783..394466) Helicobacter acinonychis str. Sheeba 4176686 YP_664279.1 CDS cheW NC_008229.1 394889 395386 R (P07365) Chemotaxis protein cheW, purine-binding chemotaxis protein; Function unclear; chemotaxis protein CheW complement(394889..395386) Helicobacter acinonychis str. Sheeba 4176603 YP_664280.1 CDS cheA NC_008229.1 395383 397806 R (P29072) Chemotaxis protein cheA (EC 2.7.3.-); High confidence in function and specificity; histidine kinase complement(395383..397806) Helicobacter acinonychis str. Sheeba 4176599 YP_664281.1 CDS cheV NC_008229.1 397862 398800 R (P37599) Chemotaxis protein cheV; High confidence in function and specificity; chemotaxis protein CheV complement(397862..398800) Helicobacter acinonychis str. Sheeba 4176600 YP_664282.1 CDS Hac_0452 NC_008229.1 398804 399565 R (P44046) UDP-23-diacylglucosamine hydrolase (EC 3.6.1.-); High confidence in function and specificity; hypothetical protein complement(398804..399565) Helicobacter acinonychis str. Sheeba 4176146 YP_664283.1 CDS Hac_0453 NC_008229.1 399567 400235 R (Q9ZKF2) Hypothetical UPF0001 protein JHP0986; Specificity unclear; hypothetical protein complement(399567..400235) Helicobacter acinonychis str. Sheeba 4176147 YP_664284.1 CDS Hac_0454 NC_008229.1 400245 402095 R High confidence in function and specificity; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(400245..402095) Helicobacter acinonychis str. Sheeba 4176148 YP_664285.1 CDS serA NC_008229.1 402098 403672 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(402098..403672) Helicobacter acinonychis str. Sheeba 4177174 YP_664286.1 CDS Hac_0456 NC_008229.1 403688 404200 R hypothetical protein complement(403688..404200) Helicobacter acinonychis str. Sheeba 4176149 YP_664287.1 CDS rpsA NC_008229.1 404229 405887 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(404229..405887) Helicobacter acinonychis str. Sheeba 4177141 YP_664288.1 CDS ispH NC_008229.1 406005 406817 R catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase complement(406005..406817) Helicobacter acinonychis str. Sheeba 4177631 YP_664289.1 CDS aroA NC_008229.1 406819 408108 R catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase complement(406819..408108) Helicobacter acinonychis str. Sheeba 4176932 YP_664290.1 CDS pheT NC_008229.1 408124 410415 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(408124..410415) Helicobacter acinonychis str. Sheeba 4176779 YP_664291.1 CDS pheS NC_008229.1 410415 411401 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(410415..411401) Helicobacter acinonychis str. Sheeba 4176778 YP_664292.1 CDS ycfF NC_008229.1 411482 411796 D (P56147) Hypothetical HIT-like protein HP0404/JHP0977; High confidence in function and specificity; HIT-family protein 411482..411796 Helicobacter acinonychis str. Sheeba 4176646 YP_664293.1 CDS Hac_0463 NC_008229.1 411815 413137 D (Q9X191) Probable cysteine desulfurase (EC 4.4.1.-or 2.8.1.7); High confidence in function and specificity; aminotransferase 411815..413137 Helicobacter acinonychis str. Sheeba 4176150 YP_664294.1 CDS Hac_0464 NC_008229.1 413163 413753 D hypothetical protein 413163..413753 Helicobacter acinonychis str. Sheeba 4176151 YP_664295.1 CDS Hac_0465 NC_008229.1 414083 414562 D hypothetical protein 414083..414562 Helicobacter acinonychis str. Sheeba 4176152 YP_664296.1 CDS guaA NC_008229.1 414573 416099 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 414573..416099 Helicobacter acinonychis str. Sheeba 4177275 YP_664297.1 CDS hpaA NC_008229.1 416178 416927 D (Q48261) Neuraminyllactose-binding hemagglutinin precursor (N-acetylneuraminyllactose-binding fibrillar hemagglutinin receptor-binding subunit) (NLBH) (Flagellar sheath adhesin), neuraminyllactose-binding hemagglutinin homolog (hpaA); High confidence in function and specificity; neuraminyllactose-binding hemagglutinin 416178..416927 Helicobacter acinonychis str. Sheeba 4176880 YP_664298.1 CDS Hac_0471 NC_008229.1 418498 419004 D hypothetical protein 418498..419004 Helicobacter acinonychis str. Sheeba 4176153 YP_664299.1 CDS Hac_0472 NC_008229.1 419193 419723 R hypothetical protein complement(419193..419723) Helicobacter acinonychis str. Sheeba 4176154 YP_664300.1 CDS Hac_0473 NC_008229.1 419925 421148 D (Q10071) Probable CAAX prenyl protease 1 (EC 3.4.24.84) (Prenyl protein-specific endoprotease 1) (PPSEP 1); High confidence in function and specificity; integral membrane zinc-metalloprotease 419925..421148 Helicobacter acinonychis str. Sheeba 4176155 YP_664301.1 CDS hemK NC_008229.1 421145 421975 D (O66506) HemK protein homolog (EC 2.1.1.-) (M.AaoHemKP); High confidence in function and specificity; protoporphyrinogen oxidase 421145..421975 Helicobacter acinonychis str. Sheeba 4177427 YP_664302.1 CDS gdhA NC_008229.1 422135 423481 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 422135..423481 Helicobacter acinonychis str. Sheeba 4177761 YP_664303.1 CDS fragment 4 NC_008229.1 423610 424257 R Function unclear; hypothetical protein complement(423610..424257) Helicobacter acinonychis str. Sheeba 4177297 YP_664304.1 CDS fragment 3 NC_008229.1 424282 424407 R Function unclear; hypothetical protein complement(424282..424407) Helicobacter acinonychis str. Sheeba 4177279 YP_664305.1 CDS fragment 2 NC_008229.1 424432 424818 R Function unclear; hypothetical protein complement(424432..424818) Helicobacter acinonychis str. Sheeba 4177225 YP_664306.1 CDS fragment 1 NC_008229.1 424799 424930 R Function unclear; hypothetical protein complement(424799..424930) Helicobacter acinonychis str. Sheeba 4176343 YP_664307.1 CDS fucT fragment 3 NC_008229.1 424990 426219 R (Q9LJK1) Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(13)-fucosyltransferase) (Fuc-T C3) (FucTA) (FucT1) (AtFUT11); hypothetical protein; alpha (1,3)-fucosyltransferase fragment 3 complement(424990..426219) Helicobacter acinonychis str. Sheeba 4177015 YP_664308.1 CDS fucT fragment 2 NC_008229.1 426191 426361 R alpha (1,3)-fucosyltransferase fragment-2; hypothetical protein; alpha (1,3)-fucosyltransferase fragment 2 complement(426191..426361) Helicobacter acinonychis str. Sheeba 4177013 YP_664309.1 CDS fucT fragment 1 NC_008229.1 426374 426622 R alpha-1,4 fucosyltransferase (fucTIII) gene; hypothetical protein; alpha (1,3)-fucosyltransferase fragment 1 complement(426374..426622) Helicobacter acinonychis str. Sheeba 4177011 YP_664310.1 CDS serB NC_008229.1 426787 427410 R (P44997) Phosphoserine phosphatase (EC 3.1.3.3) (PSP) (O-phosphoserine phosphohydrolase) (PSPase); High confidence in function and specificity; hypothetical protein complement(426787..427410) Helicobacter acinonychis str. Sheeba 4177175 YP_664311.1 CDS pfr NC_008229.1 427426 427929 R High confidence in function and specificity; ferritin complement(427426..427929) Helicobacter acinonychis str. Sheeba 4176751 YP_664312.1 CDS fucT N-terminal fragment NC_008229.1 428117 428485 R ALPHA (1,3)-FUCOSYLTRANSFERASE [Helicobacter pylori J99]; hypothetical protein; alpha-1,3/4-fucosyltransferase N-terminal fragment complement(428117..428485) Helicobacter acinonychis str. Sheeba 4177016 YP_664313.1 CDS ycf5 NC_008229.1 428495 431305 R High confidence in function and specificity; cytochrome c biogenesis protein complement(428495..431305) Helicobacter acinonychis str. Sheeba 4176645 YP_664314.1 CDS dsbC NC_008229.1 431315 431989 R High confidence in function and specificity; disulfide interchange protein complement(431315..431989) Helicobacter acinonychis str. Sheeba 4176384 YP_664315.1 CDS hemH NC_008229.1 432073 433089 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(432073..433089) Helicobacter acinonychis str. Sheeba 4177426 YP_664316.1 CDS Hac_0491 NC_008229.1 433155 433574 D hypothetical protein 433155..433574 Helicobacter acinonychis str. Sheeba 4176156 YP_664317.1 CDS Hac_0492 NC_008229.1 433575 434255 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 433575..434255 Helicobacter acinonychis str. Sheeba 4176157 YP_664318.1 CDS Hac_0493 NC_008229.1 434373 434930 R hypothetical protein complement(434373..434930) Helicobacter acinonychis str. Sheeba 4176158 YP_664319.1 CDS Hac_0494 NC_008229.1 434930 435892 R (P29749) Modification methylase TthHB8I (EC 2.1.1.72) (Adenine-specific methyltransferase TthHB8I) (M.TthHB8I); hypothetical protein; type II DNA modification enzyme (methyltransferase) complement(434930..435892) Helicobacter acinonychis str. Sheeba 4176159 YP_664320.1 CDS dcd NC_008229.1 435972 436538 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(435972..436538) Helicobacter acinonychis str. Sheeba 4176407 YP_664321.1 CDS accB NC_008229.1 436662 437135 D (Q9PKR5) Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP); High confidence in function and specificity; acetyl-CoA carboxylase biotin carboxyl carrier protein 436662..437135 Helicobacter acinonychis str. Sheeba 4177691 YP_664322.1 CDS accC NC_008229.1 437141 438508 D biotin carboxylase; biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase 437141..438508 Helicobacter acinonychis str. Sheeba 4177692 YP_664323.1 CDS Hac_0498 NC_008229.1 438530 438949 D hypothetical protein 438530..438949 Helicobacter acinonychis str. Sheeba 4176218 YP_664324.1 CDS Hac_0499 NC_008229.1 438931 439464 D hypothetical protein 438931..439464 Helicobacter acinonychis str. Sheeba 4176219 YP_664325.1 CDS Hac_0500 NC_008229.1 439482 439652 D hypothetical protein 439482..439652 Helicobacter acinonychis str. Sheeba 4176220 YP_664326.1 CDS vacA beta fragment 13 NC_008229.1 439904 440122 R vacuolating cytotoxin (vacA) pseudogene; High confidence in function and specificity; vacuolating cytotoxin fragment 13 complement(439904..440122) Helicobacter acinonychis str. Sheeba 4176703 YP_664327.1 CDS vacA beta fragment 12 NC_008229.1 440209 440343 R vacuolating cytotoxin (vacA) pseudogene; hypothetical protein; vacuolating cytotoxin fragment 12 complement(440209..440343) Helicobacter acinonychis str. Sheeba 4176702 YP_664328.1 CDS vacA beta fragment 11 NC_008229.1 440368 440568 R vacuolating cytotoxin (vacA) pseudogene; High confidence in function and specificity; vacuolating cytotoxin fragment 11 complement(440368..440568) Helicobacter acinonychis str. Sheeba 4176701 YP_664329.1 CDS vacA beta fragment 10 NC_008229.1 440584 440856 R vacuolating cytotoxin (vacA) pseudogene; High confidence in function and specificity; vacuolating cytotoxin fragment 10 complement(440584..440856) Helicobacter acinonychis str. Sheeba 4176700 YP_664330.1 CDS vacA beta fragment 9 NC_008229.1 440927 441049 R vacuolating cytotoxin (vacA) pseudogene; hypothetical protein; vacuolating cytotoxin fragment 9 complement(440927..441049) Helicobacter acinonychis str. Sheeba 4176614 YP_664331.1 CDS vacA beta fragment 8 NC_008229.1 441195 441515 R (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity; vacuolating cytotoxin fragment 8 complement(441195..441515) Helicobacter acinonychis str. Sheeba 4176613 YP_664332.1 CDS vacA beta fragment 7 NC_008229.1 441532 442062 R vacuolating cytotoxin (vacA) pseudogene, partial sequence; High confidence in function and specificity; vacuolating cytotoxin fragment 7 complement(441532..442062) Helicobacter acinonychis str. Sheeba 4176612 YP_664333.1 CDS vacA beta fragment 6 NC_008229.1 442266 442544 R (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity; vacuolating cytotoxin fragment 6 complement(442266..442544) Helicobacter acinonychis str. Sheeba 4176611 YP_664334.1 CDS vacA beta fragment 5 NC_008229.1 442614 442829 R (Q9ZKW5) Vacuolating cytotoxin precursor; High confidence in function and specificity; vacuolating cytotoxin fragment 5 complement(442614..442829) Helicobacter acinonychis str. Sheeba 4176610 YP_664335.1 CDS vacA beta fragment 4 NC_008229.1 442842 442958 R (P55981) Vacuolating cytotoxin precursor; hypothetical protein; vacuolating cytotoxin fragment 4 complement(442842..442958) Helicobacter acinonychis str. Sheeba 4176609 YP_664336.1 CDS vacA beta fragment 3 NC_008229.1 442980 443192 R (Q48258) Vacuolating cytotoxin precursor; Conserved hypothetical protein; vacuolating cytotoxin fragment 3 complement(442980..443192) Helicobacter acinonychis str. Sheeba 4176608 YP_664337.1 CDS vacA beta fragment 2 NC_008229.1 443167 443457 R (Q48253) Vacuolating cytotoxin precursor, vacA fragment-2; High confidence in function and specificity; vacuolating cytotoxin fragment 2 complement(443167..443457) Helicobacter acinonychis str. Sheeba 4176704 YP_664338.1 CDS vacA beta fragment 1 NC_008229.1 443524 443718 R (Q48253) Vacuolating cytotoxin precursor,vacuolating cytotoxin (vacA) pseudogene, partial sequence; High confidence in function and specificity; vacuolating cytotoxin fragment 1 complement(443524..443718) Helicobacter acinonychis str. Sheeba 4176699 YP_664339.1 CDS Hac_0517 NC_008229.1 444255 444863 D High confidence in function and specificity; hypothetical protein 444255..444863 Helicobacter acinonychis str. Sheeba 4176221 YP_664340.1 CDS Hac_0518 NC_008229.1 444860 445984 D High confidence in function and specificity; sugar nucleotide biosynthesis 444860..445984 Helicobacter acinonychis str. Sheeba 4176222 YP_664341.1 CDS mjaVIP NC_008229.1 445987 446709 D Specificity unclear; endonuclease MjaVIP 445987..446709 Helicobacter acinonychis str. Sheeba 4176770 YP_664342.1 CDS hpaim NC_008229.1 446706 447464 D High confidence in function and specificity; adenine specific DNA methyltransferase 446706..447464 Helicobacter acinonychis str. Sheeba 4176883 YP_664343.1 CDS clpB NC_008229.1 447538 450108 D (Q9ZMH1) ClpB protein; High confidence in function and specificity; ATP-dependent Clp protease, ATP-binding subunit ClpB 447538..450108 Helicobacter acinonychis str. Sheeba 4176607 YP_664344.1 CDS ccdA NC_008229.1 450166 450885 D (P44202) Hypothetical cytochrome c-type biogenesis protein HI1454; High confidence in function and specificity; cytochrome c-type biogenesis protein ccdA 450166..450885 Helicobacter acinonychis str. Sheeba 4176593 YP_664345.1 CDS pyrC NC_008229.1 450895 452028 D High confidence in function and specificity; dihydroorotase 450895..452028 Helicobacter acinonychis str. Sheeba 4177750 YP_664346.1 CDS Hac_0525 NC_008229.1 452016 453242 D Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline; chlorohydrolase 452016..453242 Helicobacter acinonychis str. Sheeba 4176223 YP_664347.1 CDS Hac_0526 NC_008229.1 453381 453623 D hypothetical protein 453381..453623 Helicobacter acinonychis str. Sheeba 4176224 YP_664348.1 CDS Hac_0527 NC_008229.1 453666 454949 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 453666..454949 Helicobacter acinonychis str. Sheeba 4176225 YP_664349.1 CDS Hac_0528 NC_008229.1 454985 455632 D Specificity unclear; hypothetical protein 454985..455632 Helicobacter acinonychis str. Sheeba 4176226 YP_664350.1 CDS Hac_0529 NC_008229.1 455625 456608 D hypothetical protein 455625..456608 Helicobacter acinonychis str. Sheeba 4176227 YP_664351.1 CDS Hac_0530 NC_008229.1 456598 457119 D hypothetical protein 456598..457119 Helicobacter acinonychis str. Sheeba 4176228 YP_664352.1 CDS Hac_0531 NC_008229.1 457139 457669 D hypothetical protein 457139..457669 Helicobacter acinonychis str. Sheeba 4176229 YP_664353.1 CDS Hac_0532 NC_008229.1 457678 458076 D (Q9ZMG1) similar to Hypothetical protein JHP0259; Specificity unclear; hypothetical protein 457678..458076 Helicobacter acinonychis str. Sheeba 4176230 YP_664354.1 CDS addB NC_008229.1 458113 459408 D Function unclear; ATP-dependent nuclease 458113..459408 Helicobacter acinonychis str. Sheeba 4177699 YP_664355.1 CDS trpC NC_008229.1 459396 459953 D (Q9PI11) Indole-3-glycerol phosphate synthase (EC 4.1.1.48) (IGPS); High confidence in function and specificity; indole-3-glycerol phosphate synthase 459396..459953 Helicobacter acinonychis str. Sheeba 4177495 YP_664356.1 CDS fdx NC_008229.1 460009 460260 D High confidence in function and specificity; hypothetical protein 460009..460260 Helicobacter acinonychis str. Sheeba 4176810 YP_664357.1 CDS ppx NC_008229.1 460271 461725 D (P25552) Guanosine-5-triphosphate3-diphosphate pyrophosphatase (EC 3.6.1.40) (Guanosine pentaphosphate phosphohydrolase) (pppGpp-5-phosphohydrolase); High confidence in function and specificity; hypothetical protein 460271..461725 Helicobacter acinonychis str. Sheeba 4176557 YP_664358.1 CDS rfaC NC_008229.1 461722 462732 D (P37692) ADP-heptose--LPS heptosyltransferase II (EC 2.4.1.-); High confidence in function and specificity; lipopolysaccharide heptosyltransferase-1 461722..462732 Helicobacter acinonychis str. Sheeba 4177077 YP_664359.1 CDS Hac_0538 NC_008229.1 462729 463715 D acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; essential for survival; plays a role in cell responses to environmental changes; lipid A biosynthesis lauroyl acyltransferase 462729..463715 Helicobacter acinonychis str. Sheeba 4176231 YP_664360.1 CDS tgt NC_008229.1 463980 465095 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(463980..465095) Helicobacter acinonychis str. Sheeba 4177473 YP_664361.1 CDS Hac_0542 NC_008229.1 465151 466587 D (Q91AV2) Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Includes: Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains: p9; p87; p195 (EC 3.4.24.-) (Papain-like proteinases 1/2) (PL1-PRO/PL2-PRO); Peptide HD2; Unknown protein 1; 3C-like; Function unclear; hypothetical protein 465151..466587 Helicobacter acinonychis str. Sheeba 4176232 YP_664362.1 CDS aroB NC_008229.1 466592 467623 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 466592..467623 Helicobacter acinonychis str. Sheeba 4176934 YP_664363.1 CDS Hac_0544 NC_008229.1 467629 469170 D (Q58111) similar to Hypothetical UPF0003 protein MJ0700; Specificity unclear; hypothetical protein 467629..469170 Helicobacter acinonychis str. Sheeba 4176233 YP_664364.1 CDS Hac_0545 NC_008229.1 469176 470432 D (Q9ZMF0) similar to Hypothetical protein JHP0270; Specificity unclear; hypothetical protein 469176..470432 Helicobacter acinonychis str. Sheeba 4176234 YP_664365.1 CDS ftsH NC_008229.1 470419 472071 D (Q9TJ83) Cell division protein ftsH homolog (EC 3.4.24.-) (FtsHCP); High confidence in function and specificity; cell division protein FtsH3 470419..472071 Helicobacter acinonychis str. Sheeba 4176527 YP_664366.1 CDS Hac_0547 NC_008229.1 472075 472593 D hypothetical protein 472075..472593 Helicobacter acinonychis str. Sheeba 4176235 YP_664367.1 CDS Hac_0548 NC_008229.1 472606 473091 D hypothetical protein 472606..473091 Helicobacter acinonychis str. Sheeba 4176236 YP_664368.1 CDS vacA NC_008229.1 473155 481887 D (Q48253) Vacuolating cytotoxin precursor; Specificity unclear; vacuolating cytotoxin VacA 473155..481887 Helicobacter acinonychis str. Sheeba 4176698 YP_664369.1 CDS lysA NC_008229.1 481935 483152 D (Q9ZME5) Diaminopimelate decarboxylase (EC 4.1.1.20) (DAP decarboxylase); High confidence in function and specificity; hypothetical protein 481935..483152 Helicobacter acinonychis str. Sheeba 4177628 YP_664370.1 CDS Hac_0551 NC_008229.1 483157 483441 D (P43902) T-protein [Includes: Chorismate mutase (EC 5.4.99.5) (CM); Prephenate dehydrogenase (EC 1.3.1.12) (PDH)]; High confidence in function and specificity; hypothetical protein 483157..483441 Helicobacter acinonychis str. Sheeba 4177378 YP_664371.1 CDS Hac_0552 NC_008229.1 483454 484326 D (P33275) Hypothetical protein MYCGA3080; Specificity unclear; hypothetical protein 483454..484326 Helicobacter acinonychis str. Sheeba 4177379 YP_664372.1 CDS pabB NC_008229.1 484327 486018 D (P05041) Para-aminobenzoate synthase component I (EC 6.3.5.8) (ADC synthase)[EC:6.3.5.8 4.1.3.38]; High confidence in function and specificity; para-aminobenzoate synthetase component I 484327..486018 Helicobacter acinonychis str. Sheeba 4177333 YP_664373.1 CDS amiE NC_008229.1 486213 487232 D aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates; acylamide amidohydrolase 486213..487232 Helicobacter acinonychis str. Sheeba 4177703 YP_664374.1 CDS flgL NC_008229.1 487312 489795 R with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgL complement(487312..489795) Helicobacter acinonychis str. Sheeba 4177251 YP_664375.1 CDS rplU NC_008229.1 490041 490355 D High confidence in function and specificity; 50S ribosomal protein L21 490041..490355 Helicobacter acinonychis str. Sheeba 4176851 YP_664376.1 CDS rpmA NC_008229.1 490369 490635 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 490369..490635 Helicobacter acinonychis str. Sheeba 4176856 YP_664377.1 CDS dppA NC_008229.1 490752 492392 D High confidence in function and specificity; dipeptide transport system substrate-binding protein 490752..492392 Helicobacter acinonychis str. Sheeba 4176378 YP_664378.1 CDS dppB NC_008229.1 492403 493407 D (P37316) Dipeptide transport system permease dppB; High confidence in function and specificity; dipeptide transport system permease 492403..493407 Helicobacter acinonychis str. Sheeba 4176379 YP_664379.1 CDS dppC NC_008229.1 493407 494264 D (P94312) Dipeptide transport system permease dppC; High confidence in function and specificity; dipeptide transport system permease 493407..494264 Helicobacter acinonychis str. Sheeba 4176380 YP_664380.1 CDS dppD NC_008229.1 494275 495138 D (P42064) Oligopeptide transport ATP-binding protein appD; High confidence in function and specificity; dipeptide transport system ATP-binding protein 494275..495138 Helicobacter acinonychis str. Sheeba 4176381 YP_664381.1 CDS dppF NC_008229.1 495135 495941 D (P37313) Dipeptide transport ATP-binding protein dppF; High confidence in function and specificity; dipeptide transport system ATP-binding protein 495135..495941 Helicobacter acinonychis str. Sheeba 4176382 YP_664382.1 CDS obgE NC_008229.1 495956 497038 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 495956..497038 Helicobacter acinonychis str. Sheeba 4176465 YP_664383.1 CDS Hac_0565 NC_008229.1 497080 498075 D Similar to H. pylori predicted coding region HP0304; hypothetical protein; hypothetical protein 497080..498075 Helicobacter acinonychis str. Sheeba 4177380 YP_664384.1 CDS Hac_0567 NC_008229.1 500460 500654 D hypothetical protein 500460..500654 Helicobacter acinonychis str. Sheeba 4177381 YP_664385.1 CDS omp5 NC_008229.1 500799 502844 D outer membrane protein, similar to Hop family; High confidence in function and specificity; outer membrane protein 5 500799..502844 Helicobacter acinonychis str. Sheeba 4176434 YP_664386.1 CDS Hac_0571 NC_008229.1 503002 504285 D similar to HP1143; Function unclear; hypothetical protein 503002..504285 Helicobacter acinonychis str. Sheeba 4177382 YP_664387.1 CDS Hac_0572 NC_008229.1 504345 506780 D Function unclear; hypothetical protein 504345..506780 Helicobacter acinonychis str. Sheeba 4177383 YP_664388.1 CDS fmt NC_008229.1 506795 507712 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 506795..507712 Helicobacter acinonychis str. Sheeba 4177507 YP_664389.1 CDS birA NC_008229.1 507709 508347 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 507709..508347 Helicobacter acinonychis str. Sheeba 4177119 YP_664390.1 CDS parA NC_008229.1 508350 509144 D High confidence in function and specificity; partition protein, ParA-like protein 508350..509144 Helicobacter acinonychis str. Sheeba 4176735 YP_664391.1 CDS parB NC_008229.1 509147 510016 D High confidence in function and specificity; chromosome partitioning protein parB 509147..510016 Helicobacter acinonychis str. Sheeba 4176737 YP_664392.1 CDS atpF' NC_008229.1 510131 510565 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; F0F1 ATP synthase subunit B' 510131..510565 Helicobacter acinonychis str. Sheeba 4177108 YP_664393.1 CDS atpF NC_008229.1 510569 511084 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 510569..511084 Helicobacter acinonychis str. Sheeba 4177107 YP_664394.1 CDS atpH NC_008229.1 511085 511627 D produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 511085..511627 Helicobacter acinonychis str. Sheeba 4177110 YP_664395.1 CDS atpA NC_008229.1 511650 513161 D produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 511650..513161 Helicobacter acinonychis str. Sheeba 4177102 YP_664396.1 CDS atpG NC_008229.1 513176 514081 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 513176..514081 Helicobacter acinonychis str. Sheeba 4177109 YP_664397.1 CDS atpD NC_008229.1 514109 515509 D Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 514109..515509 Helicobacter acinonychis str. Sheeba 4177105 YP_664398.1 CDS atpC NC_008229.1 515519 515890 D part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 515519..515890 Helicobacter acinonychis str. Sheeba 4177104 YP_664399.1 CDS exbB NC_008229.1 515900 516490 D (O25755) biopolymer transport exbB-like protein; High confidence in function and specificity; biopolymer transport protein 515900..516490 Helicobacter acinonychis str. Sheeba 4177402 YP_664400.1 CDS exbD NC_008229.1 516519 516920 D (Q9ZK84) biopolymer transport exbD-like protein; High confidence in function and specificity; hypothetical protein 516519..516920 Helicobacter acinonychis str. Sheeba 4177405 YP_664401.1 CDS Hac_0586 NC_008229.1 516939 517721 D similar to hypothetical protein jhp1056 -Helicobacter pylori (strain J99); High confidence in function and specificity; hypothetical protein 516939..517721 Helicobacter acinonychis str. Sheeba 4177384 YP_664402.1 CDS tolB NC_008229.1 517718 518971 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 517718..518971 Helicobacter acinonychis str. Sheeba 4177485 YP_664403.1 CDS pal NC_008229.1 519050 519595 D (P43036) Peptidoglycan-associated lipoprotein precursor, OmpA family, palA, excC; Function unclear; peptidoglycan-associated lipoprotein 519050..519595 Helicobacter acinonychis str. Sheeba 4177335 YP_664404.1 CDS Hac_0589 NC_008229.1 519603 520595 D hypothetical protein 519603..520595 Helicobacter acinonychis str. Sheeba 4177385 YP_664405.1 CDS slyD NC_008229.1 520582 521136 D (Q9ZK89) FKBP-type peptidyl-prolyl cis-trans isomerase slyD (EC 5.2.1.8) (PPIase) (Rotamase); High confidence in function and specificity; FKBP-type peptidyl-prolyl cis-trans isomerase 520582..521136 Helicobacter acinonychis str. Sheeba 4177457 YP_664406.1 CDS Hac_0591 NC_008229.1 521165 521371 D hypothetical protein 521165..521371 Helicobacter acinonychis str. Sheeba 4177386 YP_664407.1 CDS flgM NC_008229.1 521438 521641 D FlgM protein 521438..521641 Helicobacter acinonychis str. Sheeba 4177252 YP_664408.1 CDS BSP6IM NC_008229.1 521790 522737 D (P34877) Modification methylase ScrFIA (EC 2.1.1.37) (Cytosine-specific methyltransferase ScrFIA) (M.ScrFIA) (M.ScrFI-A); High confidence in function and specificity; C-5 cytosine-specific DNA methylase 521790..522737 Helicobacter acinonychis str. Sheeba 4177120 YP_664409.1 CDS Hac_0596 NC_008229.1 522888 523322 D hypothetical protein 522888..523322 Helicobacter acinonychis str. Sheeba 4177387 YP_664410.1 CDS flgK NC_008229.1 523324 525144 D with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 523324..525144 Helicobacter acinonychis str. Sheeba 4177250 YP_664411.1 CDS ggt NC_008229.1 525497 527200 D (P36267) Gamma-glutamyltranspeptidase precursor (EC 2.3.2.2); High confidence in function and specificity; hypothetical protein 525497..527200 Helicobacter acinonychis str. Sheeba 4177762 YP_664412.1 CDS Hac_0600 NC_008229.1 527458 528234 D Function unclear; hypothetical protein 527458..528234 Helicobacter acinonychis str. Sheeba 4177388 YP_664413.1 CDS Hac_0603 NC_008229.1 528705 530573 D similar to HP0415; High confidence in function and specificity; hypothetical protein 528705..530573 Helicobacter acinonychis str. Sheeba 4177389 YP_664414.1 CDS cfa NC_008229.1 530576 531745 R High confidence in function and specificity; cyclopropane-fatty-acyl-phospholipid synthase complement(530576..531745) Helicobacter acinonychis str. Sheeba 4176598 YP_664415.1 CDS metS NC_008229.1 531922 533853 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 531922..533853 Helicobacter acinonychis str. Sheeba 4176763 YP_664416.1 CDS Hac_0606 NC_008229.1 533854 534861 D hypothetical protein 533854..534861 Helicobacter acinonychis str. Sheeba 4177390 YP_664417.1 CDS Hac_0607 NC_008229.1 534865 535653 D High confidence in function and specificity; methyltransferase 534865..535653 Helicobacter acinonychis str. Sheeba 4177391 YP_664418.1 CDS Hac_0608 NC_008229.1 535675 536103 D High confidence in function and specificity; hypothetical protein 535675..536103 Helicobacter acinonychis str. Sheeba 4177392 YP_664419.1 CDS capJ NC_008229.1 536110 537282 D polysaccharide biosynthesis protein; Function unclear; type 1 capsular polysaccharide biosynthesis protein J 536110..537282 Helicobacter acinonychis str. Sheeba 4176590 YP_664420.1 CDS speA NC_008229.1 537294 539141 D catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 537294..539141 Helicobacter acinonychis str. Sheeba 4177460 YP_664421.1 CDS Hac_0611 NC_008229.1 539236 540135 R hypothetical protein complement(539236..540135) Helicobacter acinonychis str. Sheeba 4177393 YP_664422.1 CDS fragment 2 NC_008229.1 540292 540471 R hypothetical protein complement(540292..540471) Helicobacter acinonychis str. Sheeba 4177226 YP_664423.1 CDS fragment 1 NC_008229.1 540527 540883 R fragment; hypothetical protein; hypothetical protein complement(540527..540883) Helicobacter acinonychis str. Sheeba 4176344 YP_664424.1 CDS Hac_0615 NC_008229.1 540978 541400 R hypothetical protein complement(540978..541400) Helicobacter acinonychis str. Sheeba 4177394 YP_664425.1 CDS Hac_0616 NC_008229.1 541411 542136 R Function unclear; hypothetical protein complement(541411..542136) Helicobacter acinonychis str. Sheeba 4177395 YP_664426.1 CDS fragment 2 NC_008229.1 542169 542294 R hypothetical protein complement(542169..542294) Helicobacter acinonychis str. Sheeba 4177227 YP_664427.1 CDS fragment 1 NC_008229.1 542287 542610 R hypothetical protein complement(542287..542610) Helicobacter acinonychis str. Sheeba 4176345 YP_664428.1 CDS Hac_0620 NC_008229.1 546569 546895 D hypothetical protein 546569..546895 Helicobacter acinonychis str. Sheeba 4177396 YP_664429.1 CDS Hac_0621 NC_008229.1 547037 547225 D hypothetical protein 547037..547225 Helicobacter acinonychis str. Sheeba 4177397 YP_664430.1 CDS Hac_0622 NC_008229.1 547252 547431 D hypothetical protein 547252..547431 Helicobacter acinonychis str. Sheeba 4176647 YP_664431.1 CDS Hac_0623 NC_008229.1 547433 547861 D hypothetical protein 547433..547861 Helicobacter acinonychis str. Sheeba 4176648 YP_664432.1 CDS Hac_0625 NC_008229.1 548265 549089 D High confidence in function and specificity; hypothetical protein 548265..549089 Helicobacter acinonychis str. Sheeba 4176649 YP_664433.1 CDS fragment 1 NC_008229.1 549213 549647 D fragment; Function unclear; hypothetical protein 549213..549647 Helicobacter acinonychis str. Sheeba 4176346 YP_664434.1 CDS Hac_0627 NC_008229.1 549678 550943 D Region start changed from 550041 to 549678 (363 bases); hypothetical protein 549678..550943 Helicobacter acinonychis str. Sheeba 4176650 YP_664435.1 CDS fragment 1 NC_008229.1 551114 551233 D hypothetical protein 551114..551233 Helicobacter acinonychis str. Sheeba 4176347 YP_664436.1 CDS fragment 2 NC_008229.1 551270 551608 D hypothetical protein 551270..551608 Helicobacter acinonychis str. Sheeba 4177228 YP_664437.1 CDS fragment 3 NC_008229.1 551739 552182 D hypothetical protein 551739..552182 Helicobacter acinonychis str. Sheeba 4177280 YP_664438.1 CDS ftsZ NC_008229.1 552517 553674 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(552517..553674) Helicobacter acinonychis str. Sheeba 4177008 YP_664439.1 CDS ftsA NC_008229.1 553808 555289 R (Q9ZKM3) Cell division protein ftsA; High confidence in function and specificity; cell division protein FtsA complement(553808..555289) Helicobacter acinonychis str. Sheeba 4176525 YP_664440.1 CDS Hac_0634 NC_008229.1 555305 556768 R Function unclear; hypothetical protein complement(555305..556768) Helicobacter acinonychis str. Sheeba 4176651 YP_664441.1 CDS bioA NC_008229.1 556896 558227 D catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 556896..558227 Helicobacter acinonychis str. Sheeba 4177113 YP_664442.1 CDS pyrH NC_008229.1 558272 558994 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 558272..558994 Helicobacter acinonychis str. Sheeba 4177062 YP_664443.1 CDS rpoZ NC_008229.1 559034 559258 D Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 559034..559258 Helicobacter acinonychis str. Sheeba 4176866 YP_664444.1 CDS spoT NC_008229.1 559245 561566 D High confidence in function and specificity; GTP pyrophosphokinase 559245..561566 Helicobacter acinonychis str. Sheeba 4177462 YP_664445.1 CDS tyrS NC_008229.1 561591 562799 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 561591..562799 Helicobacter acinonychis str. Sheeba 4176679 YP_664446.1 CDS Hac_0640 NC_008229.1 562815 563906 D Specificity unclear; hypothetical protein 562815..563906 Helicobacter acinonychis str. Sheeba 4176652 YP_664447.1 CDS amiA NC_008229.1 563913 565247 D (Q9RMZ0) Hypothetical cell-wall amidase pXO2-42 precursor (EC 3.5.1.28); High confidence in function and specificity; hypothetical protein 563913..565247 Helicobacter acinonychis str. Sheeba 4176928 YP_664448.1 CDS Hac_0642 NC_008229.1 565266 566003 D hypothetical protein 565266..566003 Helicobacter acinonychis str. Sheeba 4176653 YP_664449.1 CDS Hac_0643 NC_008229.1 566008 566691 R Function unclear; hypothetical protein complement(566008..566691) Helicobacter acinonychis str. Sheeba 4176654 YP_664450.1 CDS acnB NC_008229.1 566823 569381 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 566823..569381 Helicobacter acinonychis str. Sheeba 4177695 YP_664451.1 CDS flhB NC_008229.1 570002 571078 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(570002..571078) Helicobacter acinonychis str. Sheeba 4177254 YP_664452.1 CDS fragment 1 NC_008229.1 571615 571722 D hypothetical protein 571615..571722 Helicobacter acinonychis str. Sheeba 4176348 YP_664453.1 CDS fragment 2 NC_008229.1 571734 572075 D hypothetical protein 571734..572075 Helicobacter acinonychis str. Sheeba 4177229 YP_664454.1 CDS fragment NC_008229.1 572195 572311 D hypothetical protein 572195..572311 Helicobacter acinonychis str. Sheeba 4176336 YP_664455.1 CDS fragment 1 NC_008229.1 572327 572512 D fragment; hypothetical protein; hypothetical protein 572327..572512 Helicobacter acinonychis str. Sheeba 4176349 YP_664456.1 CDS fragment 2 NC_008229.1 572509 572628 D hypothetical protein 572509..572628 Helicobacter acinonychis str. Sheeba 4177230 YP_664457.1 CDS fragment 3 NC_008229.1 572660 572980 D fragment; hypothetical protein; hypothetical protein 572660..572980 Helicobacter acinonychis str. Sheeba 4177281 YP_664458.1 CDS ftsY NC_008229.1 573198 574079 R (Q9ZL80) Cell division protein ftsY homolog; High confidence in function and specificity; cell division protein complement(573198..574079) Helicobacter acinonychis str. Sheeba 4177007 YP_664459.1 CDS Hac_0654 NC_008229.1 574085 574636 R hypothetical protein complement(574085..574636) Helicobacter acinonychis str. Sheeba 4176655 YP_664460.1 CDS Hac_0655 NC_008229.1 574761 575402 D High confidence in function and specificity; hypothetical protein 574761..575402 Helicobacter acinonychis str. Sheeba 4176656 YP_664461.1 CDS Hac_0656 NC_008229.1 575380 576891 D protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 575380..576891 Helicobacter acinonychis str. Sheeba 4176657 YP_664462.1 CDS Hac_0657 NC_008229.1 576898 578187 R (Q9WZS2) Probable multidrug resistance protein norM (Na(+)/drug antiporter) (Multidrug-efflux transporter); High confidence in function and specificity; hypothetical protein complement(576898..578187) Helicobacter acinonychis str. Sheeba 4176658 YP_664463.1 CDS Hac_0658 NC_008229.1 578214 579527 R (P46231) Hypothetical protein VP2115 (ORF3); Specificity unclear; permease complement(578214..579527) Helicobacter acinonychis str. Sheeba 4176659 YP_664464.1 CDS Hac_0661 NC_008229.1 579629 580510 R Specificity unclear; beta-alanine synthetase complement(579629..580510) Helicobacter acinonychis str. Sheeba 4176660 YP_664465.1 CDS Hac_0662 NC_008229.1 580514 580660 R hypothetical protein complement(580514..580660) Helicobacter acinonychis str. Sheeba 4176661 YP_664466.1 CDS moeB NC_008229.1 580662 581333 R High confidence in function and specificity; molybdopterin biosynthesis protein complement(580662..581333) Helicobacter acinonychis str. Sheeba 4176721 YP_664467.1 CDS Hac_0664 NC_008229.1 581387 581626 R hypothetical protein complement(581387..581626) Helicobacter acinonychis str. Sheeba 4176662 YP_664468.1 CDS fliS NC_008229.1 581613 581993 R flagellin specific chaperone; flagellar protein FliS complement(581613..581993) Helicobacter acinonychis str. Sheeba 4177505 YP_664469.1 CDS fliD NC_008229.1 582038 584095 R involved in flagellin assembly; flagellar capping protein complement(582038..584095) Helicobacter acinonychis str. Sheeba 4177257 YP_664470.1 CDS flaG NC_008229.1 584113 584478 R possibly involved in flagella export; flagellar protein FlaG complement(584113..584478) Helicobacter acinonychis str. Sheeba 4176827 YP_664471.1 CDS Hac_0668 NC_008229.1 584572 585759 R Function unclear; hypothetical protein complement(584572..585759) Helicobacter acinonychis str. Sheeba 4176663 YP_664472.1 CDS ftsX NC_008229.1 585762 586574 R (P95357) Cell division protein ftsX homolog; High confidence in function and specificity; cell division protein FtsX complement(585762..586574) Helicobacter acinonychis str. Sheeba 4177006 YP_664473.1 CDS ftsE NC_008229.1 586561 587232 R ftsE; cell division protein; High confidence in function and specificity; cell division ABC transporter ATP-binding protein FtsE complement(586561..587232) Helicobacter acinonychis str. Sheeba 4176526 YP_664474.1 CDS trmB NC_008229.1 587207 588403 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(587207..588403) Helicobacter acinonychis str. Sheeba 4176664 YP_664475.1 CDS Hac_0672 NC_008229.1 588414 589643 R FIBRONECTIN DOMAIN-CONTAINING LIPOPROTEIN; Function unclear; fibronectin domain-containing lipoprotein complement(588414..589643) Helicobacter acinonychis str. Sheeba 4176665 YP_664476.1 CDS Hac_0673 NC_008229.1 589624 590604 R High confidence in function and specificity; pseudouridine synthase complement(589624..590604) Helicobacter acinonychis str. Sheeba 4177358 YP_664477.1 CDS fragment 1 NC_008229.1 591090 591614 D fragment; Function unclear; hypothetical protein 591090..591614 Helicobacter acinonychis str. Sheeba 4176350 YP_664478.1 CDS fragment 2 NC_008229.1 591623 591946 D fragment; hypothetical protein; hypothetical protein 591623..591946 Helicobacter acinonychis str. Sheeba 4177231 YP_664479.1 CDS rodA NC_008229.1 591969 593114 D (Q9ZLA0) Rod shape-determining protein rodA; High confidence in function and specificity; rod shape-determining protein RodA 591969..593114 Helicobacter acinonychis str. Sheeba 4176830 YP_664480.1 CDS prsA NC_008229.1 593179 594114 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(593179..594114) Helicobacter acinonychis str. Sheeba 4176567 YP_664481.1 CDS Hac_0678 NC_008229.1 594178 594663 R (Q58276) Hypothetical HIT-like protein MJ0866; Specificity unclear; HIT family protein complement(594178..594663) Helicobacter acinonychis str. Sheeba 4177359 YP_664482.1 CDS murF NC_008229.1 594673 596154 R (Q8DVE3) UDP-N-acetylmuramoylalanine--D-glutamate ligase (EC 6.3.2.9) (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase) (D-glutamic acid adding enzyme); High confidence in function and specificity; D-alanyl-D-alanine-adding enzyme complement(594673..596154) Helicobacter acinonychis str. Sheeba 4177655 YP_664483.1 CDS Hac_0680 NC_008229.1 596141 596866 R Function unclear; 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase complement(596141..596866) Helicobacter acinonychis str. Sheeba 4177360 YP_664484.1 CDS ddl NC_008229.1 596866 597918 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(596866..597918) Helicobacter acinonychis str. Sheeba 4177122 YP_664485.1 CDS pgpA NC_008229.1 597993 598469 R (P18200) Phosphatidylglycerophosphatase A (EC 3.1.3.27); Function unclear; phosphatidylglycerophosphatase A complement(597993..598469) Helicobacter acinonychis str. Sheeba 4176776 YP_664486.1 CDS serC NC_008229.1 598617 599726 D (Q9ZLA7) aminotransferase JHP0673 (EC 2.6.1.-); High confidence in function and specificity; aminotransferase 598617..599726 Helicobacter acinonychis str. Sheeba 4177177 YP_664487.1 CDS gpt NC_008229.1 599735 600196 D High confidence in function and specificity; xanthine-guanine phosphoribosyltransferase 599735..600196 Helicobacter acinonychis str. Sheeba 4177270 YP_664488.1 CDS Hac_0685 NC_008229.1 600198 601514 D conserved hypothetical protein; High confidence in function and specificity; 2-methylthioadenine synthetase 600198..601514 Helicobacter acinonychis str. Sheeba 4177361 YP_664489.1 CDS fragment 1 NC_008229.1 601618 601890 D similar to HP0733 and jhp0670; hypothetical protein; hypothetical protein 601618..601890 Helicobacter acinonychis str. Sheeba 4176351 YP_664490.1 CDS fragment 2 NC_008229.1 602565 602891 D similar to HP0733 and jhp0669; hypothetical protein; hypothetical protein 602565..602891 Helicobacter acinonychis str. Sheeba 4177232 YP_664491.1 CDS fragment 3 NC_008229.1 602876 603052 D similar to HP0733 and jhp0669; hypothetical protein; hypothetical protein 602876..603052 Helicobacter acinonychis str. Sheeba 4177282 YP_664492.1 CDS fragment 4 NC_008229.1 603090 603317 D similar to HP0732 and jhp0669; hypothetical protein; hypothetical protein 603090..603317 Helicobacter acinonychis str. Sheeba 4177298 YP_664493.1 CDS fragment 1 NC_008229.1 603438 603617 D fragment; hypothetical protein; hypothetical protein 603438..603617 Helicobacter acinonychis str. Sheeba 4176352 YP_664494.1 CDS fragment 2 NC_008229.1 603685 604335 D fragment; hypothetical protein; hypothetical protein 603685..604335 Helicobacter acinonychis str. Sheeba 4177233 YP_664495.1 CDS fragment 3 NC_008229.1 604521 604967 D fragment; hypothetical protein; hypothetical protein 604521..604967 Helicobacter acinonychis str. Sheeba 4177283 YP_664496.1 CDS fragment 4 NC_008229.1 604927 605133 D fragment; hypothetical protein; hypothetical protein 604927..605133 Helicobacter acinonychis str. Sheeba 4176511 YP_664497.1 CDS Hac_0695 NC_008229.1 605231 605536 D hypothetical protein 605231..605536 Helicobacter acinonychis str. Sheeba 4177362 YP_664498.1 CDS Hac_0696 NC_008229.1 605545 606615 D ATP /GTP binding protein 605545..606615 Helicobacter acinonychis str. Sheeba 4177363 YP_664499.1 CDS Hac_0697 NC_008229.1 606620 607669 D Function unclear; hypothetical protein 606620..607669 Helicobacter acinonychis str. Sheeba 4177364 YP_664500.1 CDS gapA NC_008229.1 607818 608816 R (Q9ZKT0) Glyceraldehyde 3-phosphate dehydrogenase (EC 1.2.1.12) (GAPDH); High confidence in function and specificity; glyceraldehyde 3-phosphate dehydrogenase complement(607818..608816) Helicobacter acinonychis str. Sheeba 4177023 YP_664501.1 CDS Hac_0699 NC_008229.1 608963 609655 D (Q9ZKT1) Hypothetical protein JHP0854; Specificity unclear; hypothetical protein 608963..609655 Helicobacter acinonychis str. Sheeba 4177365 YP_664502.1 CDS carB NC_008229.1 609754 613155 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 609754..613155 Helicobacter acinonychis str. Sheeba 4176591 YP_664503.1 CDS Hac_0701 NC_008229.1 613160 613591 D hypothetical protein 613160..613591 Helicobacter acinonychis str. Sheeba 4177366 YP_664504.1 CDS frpB NC_008229.1 613795 616239 D Function unclear; iron-regulated outer membrane protein 613795..616239 Helicobacter acinonychis str. Sheeba 4176522 YP_664505.1 CDS hofG NC_008229.1 616446 617984 D hof family outer membrane protein 616446..617984 Helicobacter acinonychis str. Sheeba 4176871 YP_664506.1 CDS Hac_0704 NC_008229.1 618081 619025 R High confidence in function and specificity; hypothetical protein complement(618081..619025) Helicobacter acinonychis str. Sheeba 4177367 YP_664507.1 CDS hofC NC_008229.1 619297 620883 D hof family outer membrane protein 619297..620883 Helicobacter acinonychis str. Sheeba 4177436 YP_664508.1 CDS hofD NC_008229.1 620950 622347 D outer membrane protein; hypothetical protein; hof family outer membrane protein 620950..622347 Helicobacter acinonychis str. Sheeba 4176868 YP_664509.1 CDS Hac_0707 NC_008229.1 622386 622565 R hypothetical protein complement(622386..622565) Helicobacter acinonychis str. Sheeba 4177368 YP_664510.1 CDS Hac_0709 NC_008229.1 622840 623001 R hypothetical protein complement(622840..623001) Helicobacter acinonychis str. Sheeba 4177369 YP_664511.1 CDS mod fragment 1 NC_008229.1 623081 623722 D (P08763) Type III restriction-modification system EcoPI enzyme mod (EC 2.1.1.72) (EcoPI methyltransferase) (M.EcoPI); High confidence in function and specificity; methyltransferase fragment 1 623081..623722 Helicobacter acinonychis str. Sheeba 4176717 YP_664512.1 CDS mod fragment 2 NC_008229.1 624151 624711 D (P12364) Type III restriction-modification system EcoP15I enzyme mod (EC 2.1.1.72) (EcoP15I methyltransferase) (M.EcoP15I); High confidence in function and specificity; methyltransferase fragment 2 624151..624711 Helicobacter acinonychis str. Sheeba 4176720 YP_664513.1 CDS Hac_0712 NC_008229.1 624704 626725 D hypothetical protein 624704..626725 Helicobacter acinonychis str. Sheeba 4177370 YP_664514.1 CDS omp6 fragment 1 NC_008229.1 627521 627931 D hypothetical protein 627521..627931 Helicobacter acinonychis str. Sheeba 4176435 YP_664515.1 CDS omp6 fragment 2 NC_008229.1 627951 628058 D hypothetical protein 627951..628058 Helicobacter acinonychis str. Sheeba 4176436 YP_664516.1 CDS Hac_0715 NC_008229.1 628089 629099 R Function unclear; hypothetical protein complement(628089..629099) Helicobacter acinonychis str. Sheeba 4177371 YP_664517.1 CDS Hac_0716 NC_008229.1 629230 629847 D Function unclear; hypothetical protein 629230..629847 Helicobacter acinonychis str. Sheeba 4177372 YP_664518.1 CDS motA NC_008229.1 629929 630702 D With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 629929..630702 Helicobacter acinonychis str. Sheeba 4176722 YP_664519.1 CDS motB NC_008229.1 630705 631466 D with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 630705..631466 Helicobacter acinonychis str. Sheeba 4176723 YP_664520.1 CDS Hac_0720 NC_008229.1 631480 631911 D hypothetical protein 631480..631911 Helicobacter acinonychis str. Sheeba 4177373 YP_664521.1 CDS proWX NC_008229.1 631980 633635 D (O32243) Glycine betaine/carnitine/choline-binding protein precursor (Osmoprotectant-binding protein); High confidence in function and specificity; osmoprotection protein 631980..633635 Helicobacter acinonychis str. Sheeba 4176566 YP_664522.1 CDS proV NC_008229.1 633639 634289 D glycine betaine/choline/proline transport system ATP-binding protein,proV; glycine betaine/choline/proline transport system ATP-binding protein; High confidence in function and specificity; osmoprotection ATP-binding protein 633639..634289 Helicobacter acinonychis str. Sheeba 4176565 YP_664523.1 CDS Hac_0724 NC_008229.1 634466 634927 D hypothetical protein 634466..634927 Helicobacter acinonychis str. Sheeba 4177374 YP_664524.1 CDS uvrC NC_008229.1 634928 636712 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 634928..636712 Helicobacter acinonychis str. Sheeba 4176696 YP_664525.1 CDS hom NC_008229.1 636723 637988 D catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 636723..637988 Helicobacter acinonychis str. Sheeba 4176874 YP_664526.1 CDS Hac_0727 NC_008229.1 637989 638333 D similar to HP0823; Specificity unclear; hypothetical protein 637989..638333 Helicobacter acinonychis str. Sheeba 4177375 YP_664527.1 CDS trxA NC_008229.1 638420 638740 D (P56430) Thioredoxin (TRX); High confidence in function and specificity; thioredoxin 638420..638740 Helicobacter acinonychis str. Sheeba 4176672 YP_664528.1 CDS trxB NC_008229.1 638746 639681 D (P56431) Thioredoxin reductase (EC 1.8.1.9) (TRXR); High confidence in function and specificity; hypothetical protein 638746..639681 Helicobacter acinonychis str. Sheeba 4176673 YP_664529.1 CDS fragment 2 NC_008229.1 640116 640952 R similar to HP0629; Function unclear; hypothetical protein complement(640116..640952) Helicobacter acinonychis str. Sheeba 4177234 YP_664530.1 CDS fragment 1 NC_008229.1 640927 642174 R similar to HP0629; Function unclear; hypothetical protein complement(640927..642174) Helicobacter acinonychis str. Sheeba 4176353 YP_664531.1 CDS Hac_0733 NC_008229.1 642347 643390 R Specificity unclear; hypothetical protein complement(642347..643390) Helicobacter acinonychis str. Sheeba 4177376 YP_664532.1 CDS dapD NC_008229.1 643402 644607 R (P41396) 2345-tetrahydropyridine-26-dicarboxylate N-succinyltransferase (EC 2.3.1.117) (Tetrahydrodipicolinate N-succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase); Function unclear; hypothetical protein complement(643402..644607) Helicobacter acinonychis str. Sheeba 4176403 YP_664533.1 CDS ispG NC_008229.1 644616 645692 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(644616..645692) Helicobacter acinonychis str. Sheeba 4177760 YP_664534.1 CDS aspB NC_008229.1 645835 646962 D (O87320) aminotransferase aatC (EC 2.6.1.-); High confidence in function and specificity; hypothetical protein 645835..646962 Helicobacter acinonychis str. Sheeba 4176941 YP_664535.1 CDS murC NC_008229.1 646955 648304 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 646955..648304 Helicobacter acinonychis str. Sheeba 4177652 YP_664536.1 CDS Hac_0738 NC_008229.1 648304 648666 D hypothetical protein 648304..648666 Helicobacter acinonychis str. Sheeba 4177377 YP_664537.1 CDS mutS NC_008229.1 648666 650909 D MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; recombination and DNA strand exchange inhibitor protein 648666..650909 Helicobacter acinonychis str. Sheeba 4177658 YP_664538.1 CDS Hac_0741 NC_008229.1 650993 651820 R (Q57394) Lipooligosaccharide biosynthesis protein lic2B; Function unclear; pbeta-1,4-galactosyltransferase complement(650993..651820) Helicobacter acinonychis str. Sheeba 4176413 YP_664539.1 CDS mdaB NC_008229.1 651902 652486 R (P40717) Modulator of drug activity B; High confidence in function and specificity; modulator of drug activity B complement(651902..652486) Helicobacter acinonychis str. Sheeba 4176760 YP_664540.1 CDS hyaA NC_008229.1 652608 653765 D High confidence in function and specificity; hydrogenase small chain 652608..653765 Helicobacter acinonychis str. Sheeba 4177547 YP_664541.1 CDS hyaB NC_008229.1 653775 655511 D High confidence in function and specificity; hydrogenase large chain 653775..655511 Helicobacter acinonychis str. Sheeba 4177548 YP_664542.1 CDS hyaC NC_008229.1 655524 656192 D (P31875) Quinone-reactive Ni/Fe-hydrogenase B-type cytochrome subunit,hyaC, hydC; High confidence in function and specificity; Ni/Fe hydrogenase cytochrome b subunit 655524..656192 Helicobacter acinonychis str. Sheeba 4177549 YP_664543.1 CDS hyaD NC_008229.1 656189 656725 D High confidence in function and specificity; hydrogenase expression/formation protein 656189..656725 Helicobacter acinonychis str. Sheeba 4177550 YP_664544.1 CDS Hac_0748 NC_008229.1 656730 658280 D hydE protein; High confidence in function and specificity; hypothetical protein 656730..658280 Helicobacter acinonychis str. Sheeba 4176414 YP_664545.1 CDS Hac_0749 NC_008229.1 658286 658642 R hypothetical protein complement(658286..658642) Helicobacter acinonychis str. Sheeba 4176415 YP_664546.1 CDS Hac_0750 NC_008229.1 658724 659167 R hypothetical protein complement(658724..659167) Helicobacter acinonychis str. Sheeba 4176416 YP_664547.1 CDS omp7 fragment 1 NC_008229.1 659340 659699 D hypothetical protein 659340..659699 Helicobacter acinonychis str. Sheeba 4176437 YP_664548.1 CDS omp7 fragment 2 NC_008229.1 659786 660298 D outer membrane protein fragment; hypothetical protein; hypothetical protein 659786..660298 Helicobacter acinonychis str. Sheeba 4176438 YP_664549.1 CDS ISHa1942 tnpA NC_008229.1 660793 661197 R IS606-like IS element; Specificity unclear; ISHa1942 transposase A-like protein complement(660793..661197) Helicobacter acinonychis str. Sheeba 4176125 YP_664550.1 CDS ISHa1942 tnpB fragment 1 NC_008229.1 661311 661730 D IS605-like IS element; hypothetical protein; ISHa1942 transposase B fragment 1 661311..661730 Helicobacter acinonychis str. Sheeba 4176126 YP_664551.1 CDS ISHa1942 tnpB fragment 2 NC_008229.1 661717 662610 D IS606-like IS element; High confidence in function and specificity; ISHa1942 transposase B fragment 2 661717..662610 Helicobacter acinonychis str. Sheeba 4176127 YP_664552.1 CDS repA fragment NC_008229.1 662617 662868 R plasmid encoded: H. pylori HPM8, pHPM8;,2. H. pylori P8, pHel4; hypothetical protein; replication initiation protein A, N-terminal fragment complement(662617..662868) Helicobacter acinonychis str. Sheeba 4177074 YP_664553.1 CDS ISHa1152 tnpB fragment 3 NC_008229.1 663510 663608 R based on nucleotide blast, part of coding sequence ISHp608 orfB,ISHp608-like IS element; hypothetical protein; ISHa1152 transposase B fragment 3 complement(663510..663608) Helicobacter acinonychis str. Sheeba 4176121 YP_664554.1 CDS ISHa1152 tnpB fragment 2 NC_008229.1 663630 663755 R ISHp608-like IS element; hypothetical protein; ISHa1152 transposase B fragment 2 complement(663630..663755) Helicobacter acinonychis str. Sheeba 4177688 YP_664555.1 CDS ISHa1152 tnpB fragment 1 NC_008229.1 663712 663825 R ISHp608-like IS element; hypothetical protein; ISHa1152 transposase B fragment 1 complement(663712..663825) Helicobacter acinonychis str. Sheeba 4177686 YP_664556.1 CDS ISHa1152 tnpA NC_008229.1 663794 664198 R ISHp608-like IS element; hypothetical protein; ISHa1152 transposase A complement(663794..664198) Helicobacter acinonychis str. Sheeba 4177684 YP_664557.1 CDS mccC NC_008229.1 664803 665966 R hypothetical protein; High confidence in function and specificity; MccC-like protein complement(664803..665966) Helicobacter acinonychis str. Sheeba 4176756 YP_664558.1 CDS mccB fragment NC_008229.1 665982 666485 R MccB-like protein fragment complement(665982..666485) Helicobacter acinonychis str. Sheeba 4176755 YP_664559.1 CDS Hac_0767 NC_008229.1 666769 667446 R (P77756) Hypothetical protein; High confidence in function and specificity; hypothetical protein complement(666769..667446) Helicobacter acinonychis str. Sheeba 4176417 YP_664560.1 CDS papS NC_008229.1 667507 668664 D (Q9UTQ0) Probable tRNA nucleotidyltransferase (EC 2.7.7.19, EC 2.7.7.25) (tRNA adenylyltransferase) (tRNA CCA-pyrophosphorylase) (CCA-adding enzyme)papS,pcnB; High confidence in function and specificity; poly(A) polymerase 667507..668664 Helicobacter acinonychis str. Sheeba 4176734 YP_664561.1 CDS Hac_0770 NC_008229.1 668738 669724 D High confidence in function and specificity; transcriptional regulator 668738..669724 Helicobacter acinonychis str. Sheeba 4176418 YP_664562.1 CDS Hac_0771 NC_008229.1 669721 670653 D outer membrane protein 669721..670653 Helicobacter acinonychis str. Sheeba 4176419 YP_664563.1 CDS Hac_0772 NC_008229.1 670650 671282 R Specificity unclear; hypothetical protein complement(670650..671282) Helicobacter acinonychis str. Sheeba 4176420 YP_664564.1 CDS Hac_0773 NC_008229.1 671680 672102 D hypothetical protein 671680..672102 Helicobacter acinonychis str. Sheeba 4176421 YP_664565.1 CDS Hac_0774 NC_008229.1 672132 672602 D hypothetical protein 672132..672602 Helicobacter acinonychis str. Sheeba 4176422 YP_664566.1 CDS Hac_0776 NC_008229.1 672980 673195 D hypothetical protein 672980..673195 Helicobacter acinonychis str. Sheeba 4176423 YP_664567.1 CDS accA NC_008229.1 673769 674710 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha complement(673769..674710) Helicobacter acinonychis str. Sheeba 4177690 YP_664568.1 CDS fabF NC_008229.1 674734 675972 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II complement(674734..675972) Helicobacter acinonychis str. Sheeba 4177408 YP_664569.1 CDS acpP NC_008229.1 676076 676312 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(676076..676312) Helicobacter acinonychis str. Sheeba 4177697 YP_664570.1 CDS fabG NC_008229.1 676530 677273 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(676530..677273) Helicobacter acinonychis str. Sheeba 4177409 YP_664571.1 CDS rpsU NC_008229.1 677307 677519 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(677307..677519) Helicobacter acinonychis str. Sheeba 4176867 YP_664572.1 CDS Hac_0783 NC_008229.1 677621 678868 R hypothetical protein complement(677621..678868) Helicobacter acinonychis str. Sheeba 4176424 YP_664573.1 CDS Hac_0784 NC_008229.1 679065 679283 D hypothetical protein 679065..679283 Helicobacter acinonychis str. Sheeba 4176425 YP_664574.1 CDS Hac_0785 NC_008229.1 679317 679964 R similar to HP0565; High confidence in function and specificity; hypothetical protein complement(679317..679964) Helicobacter acinonychis str. Sheeba 4176426 YP_664575.1 CDS dapF NC_008229.1 680115 680909 R involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase complement(680115..680909) Helicobacter acinonychis str. Sheeba 4176405 YP_664576.1 CDS amaA NC_008229.1 681025 682071 D inner membrane protein; High confidence in function and specificity; hypothetical protein 681025..682071 Helicobacter acinonychis str. Sheeba 4176927 YP_664577.1 CDS flgG NC_008229.1 682144 682953 R (P75939) Flagellar basal-body rod protein flgG (Distal rod protein); Function unclear; flagellar basal-body rod protein FlgG complement(682144..682953) Helicobacter acinonychis str. Sheeba 4177247 YP_664578.1 CDS kgtP NC_008229.1 683007 684275 R (P17448) Alpha-ketoglutarate permease; High confidence in function and specificity; alpha-ketoglutarate permease complement(683007..684275) Helicobacter acinonychis str. Sheeba 4176137 YP_664579.1 CDS cpdB NC_008229.1 684478 686220 R (P44764) 23-cyclic-nucleotide 2-phosphodiesterase precursor (EC 3.1.4.16); High confidence in function and specificity; 2,3-cyclic-nucleotide 2'phosphodiesterase complement(684478..686220) Helicobacter acinonychis str. Sheeba 4176900 YP_664580.1 CDS ftsK NC_008229.1 686458 689001 R ftsK; cell division protein; High confidence in function and specificity; septum formation protein complement(686458..689001) Helicobacter acinonychis str. Sheeba 4177004 YP_664581.1 CDS Hac_0793 NC_008229.1 688998 691334 R similar to HP1089; Function unclear; hypothetical protein complement(688998..691334) Helicobacter acinonychis str. Sheeba 4176427 YP_664582.1 CDS tktA NC_008229.1 691331 693256 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(691331..693256) Helicobacter acinonychis str. Sheeba 4177481 YP_664583.1 CDS ribC NC_008229.1 693303 694142 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(693303..694142) Helicobacter acinonychis str. Sheeba 4177087 YP_664584.1 CDS tly NC_008229.1 694111 694818 R High confidence in function and specificity; hemolysin complement(694111..694818) Helicobacter acinonychis str. Sheeba 4177483 YP_664585.1 CDS Hac_0797 NC_008229.1 694818 695333 R hypothetical protein complement(694818..695333) Helicobacter acinonychis str. Sheeba 4176428 YP_664586.1 CDS pyrB NC_008229.1 695400 696326 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 695400..696326 Helicobacter acinonychis str. Sheeba 4177749 YP_664587.1 CDS hofB fragment 1 NC_008229.1 696836 697630 D hypothetical protein 696836..697630 Helicobacter acinonychis str. Sheeba 4177434 YP_664588.1 CDS hofB fragment 2 NC_008229.1 697674 698276 D hypothetical protein 697674..698276 Helicobacter acinonychis str. Sheeba 4177435 YP_664589.1 CDS msbA NC_008229.1 698367 700022 D Lipid A export ATP-binding/permease msbA; High confidence in function and specificity; multidrug resistance protein 698367..700022 Helicobacter acinonychis str. Sheeba 4176730 YP_664590.1 CDS Hac_0805 NC_008229.1 700016 700633 D hypothetical protein 700016..700633 Helicobacter acinonychis str. Sheeba 4176429 YP_664591.1 CDS Hac_0806 NC_008229.1 700637 701218 D Function unclear; hypothetical protein 700637..701218 Helicobacter acinonychis str. Sheeba 4176430 YP_664592.1 CDS Hac_0807 NC_008229.1 701203 702339 R Calcium-gated potassium channel mthK; Specificity unclear; potassium channel protein complement(701203..702339) Helicobacter acinonychis str. Sheeba 4176431 YP_664593.1 CDS rpmB NC_008229.1 702502 702690 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(702502..702690) Helicobacter acinonychis str. Sheeba 4176857 YP_664594.1 CDS hpaA NC_008229.1 702775 703608 R High confidence in function and specificity; neuraminyllactose-binding hemagglutinin complement(702775..703608) Helicobacter acinonychis str. Sheeba 4176881 YP_664595.1 CDS mraY NC_008229.1 703740 704801 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 703740..704801 Helicobacter acinonychis str. Sheeba 4176725 YP_664596.1 CDS murD NC_008229.1 704802 706070 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 704802..706070 Helicobacter acinonychis str. Sheeba 4177653 YP_664597.1 CDS Hac_0814 NC_008229.1 706171 706335 R hypothetical protein complement(706171..706335) Helicobacter acinonychis str. Sheeba 4177199 YP_664598.1 CDS Hac_0815 NC_008229.1 706325 706585 R hypothetical protein; hypothetical protein; hypothetical protein complement(706325..706585) Helicobacter acinonychis str. Sheeba 4177200 YP_664599.1 CDS Hac_0816 NC_008229.1 706575 706976 R hypothetical protein; hypothetical protein; hypothetical protein complement(706575..706976) Helicobacter acinonychis str. Sheeba 4177201 YP_664600.1 CDS Hac_0817 NC_008229.1 707182 708510 D sodium- and chloride-dependent transporter; Specificity unclear; transmembrane transport protein 707182..708510 Helicobacter acinonychis str. Sheeba 4177202 YP_664601.1 CDS fragment 1 NC_008229.1 708520 709383 D sodium-dependent transporter; Specificity unclear; sodium-and chloride-dependent transporter fragment 1 708520..709383 Helicobacter acinonychis str. Sheeba 4176354 YP_664602.1 CDS fragment 2 NC_008229.1 709395 709847 D sodium- and chloride-dependent transporter; Specificity unclear; sodium-and chloride-dependent transporter fragment 2 709395..709847 Helicobacter acinonychis str. Sheeba 4177235 YP_664603.1 CDS pldA NC_008229.1 709862 710929 D High confidence in function and specificity; phospholipase A 709862..710929 Helicobacter acinonychis str. Sheeba 4176782 YP_664604.1 CDS dnaN NC_008229.1 710984 712108 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 710984..712108 Helicobacter acinonychis str. Sheeba 4177136 YP_664605.1 CDS gyrB NC_008229.1 712120 714441 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 712120..714441 Helicobacter acinonychis str. Sheeba 4177278 YP_664606.1 CDS Hac_0823 NC_008229.1 714487 715479 D hypothetical protein 714487..715479 Helicobacter acinonychis str. Sheeba 4177203 YP_664607.1 CDS fragment 1 NC_008229.1 715499 715633 D hypothetical protein 715499..715633 Helicobacter acinonychis str. Sheeba 4176355 YP_664608.1 CDS fragment 2 NC_008229.1 716000 716230 D hypothetical protein 716000..716230 Helicobacter acinonychis str. Sheeba 4177236 YP_664609.1 CDS omp8 NC_008229.1 716271 717008 R outer membrane protein 8 complement(716271..717008) Helicobacter acinonychis str. Sheeba 4176439 YP_664610.1 CDS Hac_0827 NC_008229.1 717494 717820 D hypothetical protein 717494..717820 Helicobacter acinonychis str. Sheeba 4177204 YP_664611.1 CDS Hac_0828 NC_008229.1 717799 718401 D methylase yhhF (EC 2.1.1.-); Specificity unclear; methylase 717799..718401 Helicobacter acinonychis str. Sheeba 4177205 YP_664612.1 CDS fliL NC_008229.1 718410 718961 D interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 718410..718961 Helicobacter acinonychis str. Sheeba 4177500 YP_664613.1 CDS acpS NC_008229.1 718968 719315 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 718968..719315 Helicobacter acinonychis str. Sheeba 4177206 YP_664614.1 CDS ligA NC_008229.1 719342 721306 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(719342..721306) Helicobacter acinonychis str. Sheeba 4177615 YP_664615.1 CDS cheV NC_008229.1 721381 722322 D Chemotaxis protein cheV; High confidence in function and specificity; chemotaxis protein 721381..722322 Helicobacter acinonychis str. Sheeba 4176601 YP_664616.1 CDS aspS NC_008229.1 722349 724103 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 722349..724103 Helicobacter acinonychis str. Sheeba 4176943 YP_664617.1 CDS adk NC_008229.1 724100 724675 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 724100..724675 Helicobacter acinonychis str. Sheeba 4177701 YP_664618.1 CDS Hac_0835 NC_008229.1 724676 725725 D glycosyltransferase involved in LPS biosynthesis; High confidence in function and specificity; lipopolysaccharide biosynthesis protein 724676..725725 Helicobacter acinonychis str. Sheeba 4177207 YP_664619.1 CDS ppa NC_008229.1 725780 726301 D catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 725780..726301 Helicobacter acinonychis str. Sheeba 4176552 YP_664620.1 CDS Hac_0837 NC_008229.1 726399 726980 D hypothetical protein 726399..726980 Helicobacter acinonychis str. Sheeba 4177208 YP_664621.1 CDS Hac_0839 NC_008229.1 727784 728866 D Specificity unclear; hypothetical protein 727784..728866 Helicobacter acinonychis str. Sheeba 4177209 YP_664622.1 CDS Hac_0840 NC_008229.1 728888 731632 D High confidence in function and specificity; protective surface antigen 728888..731632 Helicobacter acinonychis str. Sheeba 4177210 YP_664623.1 CDS Hac_0841 NC_008229.1 731634 732695 D Specificity unclear; hypothetical protein 731634..732695 Helicobacter acinonychis str. Sheeba 4177211 YP_664624.1 CDS ymxG NC_008229.1 732733 733992 D High confidence in function and specificity; processing protease 732733..733992 Helicobacter acinonychis str. Sheeba 4177716 YP_664625.1 CDS gatB NC_008229.1 733992 735416 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 733992..735416 Helicobacter acinonychis str. Sheeba 4177757 YP_664626.1 CDS Hac_0844 NC_008229.1 735416 736630 D Function unclear; hypothetical protein 735416..736630 Helicobacter acinonychis str. Sheeba 4177212 YP_664627.1 CDS Hac_0845 NC_008229.1 736641 737648 D hypothetical protein 736641..737648 Helicobacter acinonychis str. Sheeba 4177213 YP_664628.1 CDS rnhA NC_008229.1 737649 738080 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 737649..738080 Helicobacter acinonychis str. Sheeba 4177095 YP_664629.1 CDS rnc NC_008229.1 738091 738795 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 738091..738795 Helicobacter acinonychis str. Sheeba 4177094 YP_664630.1 CDS aroC NC_008229.1 738792 739889 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 738792..739889 Helicobacter acinonychis str. Sheeba 4176935 YP_664631.1 CDS Hac_0849 NC_008229.1 739926 740441 D High confidence in function and specificity; hypothetical protein 739926..740441 Helicobacter acinonychis str. Sheeba 4177214 YP_664632.1 CDS hemN NC_008229.1 740441 741814 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 740441..741814 Helicobacter acinonychis str. Sheeba 4177429 YP_664633.1 CDS glpC NC_008229.1 741811 743106 D High confidence in function and specificity; glycerol-3-phosphatedehydrogenase 741811..743106 Helicobacter acinonychis str. Sheeba 4177774 YP_664634.1 CDS Hac_0852 NC_008229.1 743107 744075 D NAD-dependent deacetylase (EC 3.5.1.-) (Regulatory protein SIR2 homolog); High confidence in function and specificity; hypothetical protein 743107..744075 Helicobacter acinonychis str. Sheeba 4177215 YP_664635.1 CDS Hac_0853 NC_008229.1 744082 744849 D hypothetical protein 744082..744849 Helicobacter acinonychis str. Sheeba 4177216 YP_664636.1 CDS omp9 NC_008229.1 745060 745872 D outer membrane protein 9 745060..745872 Helicobacter acinonychis str. Sheeba 4176440 YP_664637.1 CDS aspB NC_008229.1 746025 747197 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 746025..747197 Helicobacter acinonychis str. Sheeba 4176942 YP_664638.1 CDS Hac_0857 NC_008229.1 747335 747505 D hypothetical protein 747335..747505 Helicobacter acinonychis str. Sheeba 4177217 YP_664639.1 CDS xerD NC_008229.1 747557 748642 D High confidence in function and specificity; integrase-recombinase protein 747557..748642 Helicobacter acinonychis str. Sheeba 4176640 YP_664640.1 CDS dat1 NC_008229.1 748687 749202 R Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase); High confidence in function and specificity; methylated-DNA--protein-cysteine methyltransferase complement(748687..749202) Helicobacter acinonychis str. Sheeba 4176406 YP_664641.1 CDS Hac_0860 NC_008229.1 749223 749990 R conserved hypothetical integral membrane protein, permease; Function unclear; hypothetical protein complement(749223..749990) Helicobacter acinonychis str. Sheeba 4177218 YP_664642.1 CDS wbpB NC_008229.1 750047 750991 R oxido-reductase; High confidence in function and specificity; lipopolysaccharide biosynthesis protein wbpB complement(750047..750991) Helicobacter acinonychis str. Sheeba 4176638 YP_664643.1 CDS nrdA NC_008229.1 751053 753419 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(751053..753419) Helicobacter acinonychis str. Sheeba 4177447 YP_664644.1 CDS glmU NC_008229.1 753517 754818 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(753517..754818) Helicobacter acinonychis str. Sheeba 4177768 YP_664645.1 CDS fliP NC_008229.1 754914 755660 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 754914..755660 Helicobacter acinonychis str. Sheeba 4176356 YP_664646.1 CDS fecA NC_008229.1 755701 758004 R Iron(III) dicitrate transport protein fecA; High confidence in function and specificity; iron(III) dicitrate transport protein complement(755701..758004) Helicobacter acinonychis str. Sheeba 4176811 YP_664647.1 CDS feoB NC_008229.1 758153 760081 R Ferrous iron transport protein B homolog; High confidence in function and specificity; ferrous iron transport protein B complement(758153..760081) Helicobacter acinonychis str. Sheeba 4176817 YP_664648.1 CDS Hac_0867 NC_008229.1 760216 761028 D Specificity unclear; hypothetical protein 760216..761028 Helicobacter acinonychis str. Sheeba 4176357 YP_664649.1 CDS fragment 1 NC_008229.1 761116 761244 D hypothetical protein 761116..761244 Helicobacter acinonychis str. Sheeba 4177043 YP_664650.1 CDS fragment 2 NC_008229.1 761287 761430 D hypothetical protein 761287..761430 Helicobacter acinonychis str. Sheeba 4177237 YP_664651.1 CDS Hac_0870 NC_008229.1 761563 762384 R Region start changed from 762342 to 762384 (42 bases); hypothetical protein complement(761563..762384) Helicobacter acinonychis str. Sheeba 4176358 YP_664652.1 CDS Hac_0871 NC_008229.1 762381 763346 R hypothetical protein complement(762381..763346) Helicobacter acinonychis str. Sheeba 4176359 YP_664653.1 CDS Hac_0872 NC_008229.1 763358 764041 R Function unclear; rRNA methylase complement(763358..764041) Helicobacter acinonychis str. Sheeba 4176360 YP_664654.1 CDS Hac_0873 NC_008229.1 764054 764917 R High confidence in function and specificity; methylase complement(764054..764917) Helicobacter acinonychis str. Sheeba 4176361 YP_664655.1 CDS rpmE NC_008229.1 764942 765145 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(764942..765145) Helicobacter acinonychis str. Sheeba 4176859 YP_664656.1 CDS rho NC_008229.1 765407 766723 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 765407..766723 Helicobacter acinonychis str. Sheeba 4177084 YP_664657.1 CDS murI NC_008229.1 766758 767525 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 766758..767525 Helicobacter acinonychis str. Sheeba 4177657 YP_664658.1 CDS Hac_0877 NC_008229.1 767537 768370 D Function unclear; hypothetical protein 767537..768370 Helicobacter acinonychis str. Sheeba 4176362 YP_664659.1 CDS glnA NC_008229.1 768545 769990 R Glutamine synthetase (EC 6.3.1.2) (Glutamate--ammonia ligase); High confidence in function and specificity; hypothetical protein complement(768545..769990) Helicobacter acinonychis str. Sheeba 4177769 YP_664660.1 CDS Hac_0879 NC_008229.1 770210 771115 D Region start changed from 770282 to 770210 (72 bases); hypothetical protein 770210..771115 Helicobacter acinonychis str. Sheeba 4176363 YP_664661.1 CDS fragment 2 NC_008229.1 771156 771365 D Function unclear; hypothetical protein 771156..771365 Helicobacter acinonychis str. Sheeba 4177238 YP_664662.1 CDS fragment 3 NC_008229.1 771590 772270 D High confidence in function and specificity; hypothetical protein 771590..772270 Helicobacter acinonychis str. Sheeba 4177284 YP_664663.1 CDS rplI NC_008229.1 772334 772783 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 772334..772783 Helicobacter acinonychis str. Sheeba 4176840 YP_664664.1 CDS hslV NC_008229.1 772787 773329 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 772787..773329 Helicobacter acinonychis str. Sheeba 4177541 YP_664665.1 CDS hslU NC_008229.1 773329 774660 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 773329..774660 Helicobacter acinonychis str. Sheeba 4177540 YP_664666.1 CDS era NC_008229.1 774660 775565 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 774660..775565 Helicobacter acinonychis str. Sheeba 4177399 YP_664667.1 CDS Hac_0886 NC_008229.1 775562 776554 D Function unclear; hypothetical protein 775562..776554 Helicobacter acinonychis str. Sheeba 4176364 YP_664668.1 CDS Hac_0887 NC_008229.1 776837 777124 D hypothetical protein 776837..777124 Helicobacter acinonychis str. Sheeba 4176365 YP_664669.1 CDS Hac_0889 NC_008229.1 777826 778002 D hypothetical protein 777826..778002 Helicobacter acinonychis str. Sheeba 4176366 YP_664670.1 CDS Hac_0890 NC_008229.1 778039 778335 D hypothetical protein 778039..778335 Helicobacter acinonychis str. Sheeba 4176367 YP_664671.1 CDS Hac_0891 NC_008229.1 778528 778827 D hypothetical protein 778528..778827 Helicobacter acinonychis str. Sheeba 4176368 YP_664672.1 CDS Hac_0894 NC_008229.1 780404 780529 R hypothetical protein complement(780404..780529) Helicobacter acinonychis str. Sheeba 4176369 YP_664673.1 CDS Hac_0895 NC_008229.1 780763 780978 D hypothetical protein 780763..780978 Helicobacter acinonychis str. Sheeba 4176370 YP_664674.1 CDS dapB NC_008229.1 781200 781964 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(781200..781964) Helicobacter acinonychis str. Sheeba 4176402 YP_664675.1 CDS glcD NC_008229.1 781985 783364 R Glycolate oxidase subunit glcD; High confidence in function and specificity; glycolate oxidase subunit complement(781985..783364) Helicobacter acinonychis str. Sheeba 4177765 YP_664676.1 CDS Hac_0899 NC_008229.1 783368 784615 R hypothetical protein complement(783368..784615) Helicobacter acinonychis str. Sheeba 4176371 YP_664677.1 CDS Hac_0900 NC_008229.1 784626 785261 R uridine diphosphate glucose pyrophosphatase (EC 3.6.1.45) (UGPPase) (Nucleoside diphosphate linked moiety X motif 14); High confidence in function and specificity; hypothetical protein complement(784626..785261) Helicobacter acinonychis str. Sheeba 4176372 YP_664678.1 CDS Hac_0901 NC_008229.1 785261 786484 R Specificity unclear; hypothetical protein complement(785261..786484) Helicobacter acinonychis str. Sheeba 4176373 YP_664679.1 CDS Hac_0902 NC_008229.1 786646 787923 D periplasmic protein; hypothetical protein; hypothetical protein 786646..787923 Helicobacter acinonychis str. Sheeba 4176374 YP_664680.1 CDS hofE NC_008229.1 788005 789372 D hof family outer membrane protein 788005..789372 Helicobacter acinonychis str. Sheeba 4176869 YP_664681.1 CDS Hac_0904 NC_008229.1 789379 789906 R hypothetical protein complement(789379..789906) Helicobacter acinonychis str. Sheeba 4176277 YP_664682.1 CDS lolA NC_008229.1 790376 790930 R participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein complement(790376..790930) Helicobacter acinonychis str. Sheeba 4176278 YP_664683.2 CDS secA NC_008229.1 791065 793662 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 791065..793662 Helicobacter acinonychis str. Sheeba 4177167 YP_664684.1 CDS Hac_0907 NC_008229.1 793652 794884 D High confidence in function and specificity; integral membrane protein 793652..794884 Helicobacter acinonychis str. Sheeba 4176279 YP_664685.1 CDS hofF NC_008229.1 795354 796853 D hof family outer membrane protein 795354..796853 Helicobacter acinonychis str. Sheeba 4176870 YP_664686.1 CDS fragment 3 NC_008229.1 797259 797747 R type I restriction enzyme specificity protein; Function unclear; hypothetical protein complement(797259..797747) Helicobacter acinonychis str. Sheeba 4177285 YP_664687.1 CDS fragment 2 NC_008229.1 797759 797854 R hypothetical protein complement(797759..797854) Helicobacter acinonychis str. Sheeba 4177024 YP_664688.1 CDS fragment 1 NC_008229.1 797806 797898 R hypothetical protein complement(797806..797898) Helicobacter acinonychis str. Sheeba 4177044 YP_664689.1 CDS yvgW NC_008229.1 797947 800007 R Cadmium zinc and cobalt transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); High confidence in function and specificity; heavy metal-transporting ATPase complement(797947..800007) Helicobacter acinonychis str. Sheeba 4177717 YP_664690.1 CDS Hac_0914 NC_008229.1 800032 801552 R Specificity unclear; sigma-54 interacting protein complement(800032..801552) Helicobacter acinonychis str. Sheeba 4176280 YP_664691.1 CDS def NC_008229.1 801555 802082 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(801555..802082) Helicobacter acinonychis str. Sheeba 4177124 YP_664692.1 CDS clpP NC_008229.1 802087 802674 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(802087..802674) Helicobacter acinonychis str. Sheeba 4176888 YP_664693.1 CDS tig NC_008229.1 802694 804049 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(802694..804049) Helicobacter acinonychis str. Sheeba 4177479 YP_664694.1 CDS omp10 NC_008229.1 804163 804996 R outer membrane protein 10 complement(804163..804996) Helicobacter acinonychis str. Sheeba 4176470 YP_664695.1 CDS hpaA NC_008229.1 805029 805811 R High confidence in function and specificity; neuraminyllactose-binding hemagglutinin complement(805029..805811) Helicobacter acinonychis str. Sheeba 4176882 YP_664696.1 CDS ribA NC_008229.1 805967 806545 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(805967..806545) Helicobacter acinonychis str. Sheeba 4177085 YP_664697.1 CDS Hac_0921 NC_008229.1 807137 807565 R hypothetical protein complement(807137..807565) Helicobacter acinonychis str. Sheeba 4176281 YP_664698.1 CDS Hac_0922 NC_008229.1 807567 808013 R hypothetical protein complement(807567..808013) Helicobacter acinonychis str. Sheeba 4176282 YP_664699.1 CDS Hac_0923 NC_008229.1 808024 808839 R hypothetical protein complement(808024..808839) Helicobacter acinonychis str. Sheeba 4176283 YP_664700.1 CDS ribA NC_008229.1 808924 809958 R bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein complement(808924..809958) Helicobacter acinonychis str. Sheeba 4177086 YP_664701.1 CDS Hac_0925 NC_008229.1 810038 810883 R Function unclear; lipopolysaccharide biosynthesis protein complement(810038..810883) Helicobacter acinonychis str. Sheeba 4176284 YP_664702.1 CDS Hac_0926 NC_008229.1 810963 811583 D Function unclear; metalloprotease 810963..811583 Helicobacter acinonychis str. Sheeba 4176285 YP_664703.1 CDS uvrA NC_008229.1 811634 814459 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(811634..814459) Helicobacter acinonychis str. Sheeba 4176694 YP_664704.1 CDS omp11 NC_008229.1 814638 815459 D outer membrane protein 11 814638..815459 Helicobacter acinonychis str. Sheeba 4176471 YP_664705.1 CDS mraW NC_008229.1 815539 816465 D High confidence in function and specificity; S-adenosyl-methyltransferase MraW 815539..816465 Helicobacter acinonychis str. Sheeba 4176724 YP_664706.1 CDS Hac_0930 NC_008229.1 816486 816830 D hypothetical protein 816486..816830 Helicobacter acinonychis str. Sheeba 4176286 YP_664707.1 CDS Hac_0932 NC_008229.1 816990 817892 D High confidence in function and specificity; hypothetical protein 816990..817892 Helicobacter acinonychis str. Sheeba 4176287 YP_664708.1 CDS Hac_0933 NC_008229.1 817964 819208 D Function unclear; hypothetical protein 817964..819208 Helicobacter acinonychis str. Sheeba 4176288 YP_664709.1 CDS fragment 1 NC_008229.1 819245 819343 D hypothetical protein 819245..819343 Helicobacter acinonychis str. Sheeba 4177045 YP_664710.1 CDS fragment 2 NC_008229.1 819363 819764 D High confidence in function and specificity; hypothetical protein 819363..819764 Helicobacter acinonychis str. Sheeba 4177025 YP_664711.1 CDS fragment 3 NC_008229.1 819761 819856 D hypothetical protein 819761..819856 Helicobacter acinonychis str. Sheeba 4177286 YP_664712.1 CDS rpoN NC_008229.1 819945 821189 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 complement(819945..821189) Helicobacter acinonychis str. Sheeba 4176865 YP_664713.1 CDS yhbG NC_008229.1 821192 821914 R High confidence in function and specificity; ABC transporter ATP-binding protein complement(821192..821914) Helicobacter acinonychis str. Sheeba 4177713 YP_664714.1 CDS Hac_0939 NC_008229.1 821927 822328 R Function unclear; hypothetical protein complement(821927..822328) Helicobacter acinonychis str. Sheeba 4176289 YP_664715.1 CDS dnaX NC_008229.1 822325 824055 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(822325..824055) Helicobacter acinonychis str. Sheeba 4177139 YP_664716.1 CDS omp12 fragment 5 NC_008229.1 824254 824508 R hypothetical protein complement(824254..824508) Helicobacter acinonychis str. Sheeba 4176476 YP_664717.1 CDS omp12 fragment 4 NC_008229.1 824505 824639 R hypothetical protein complement(824505..824639) Helicobacter acinonychis str. Sheeba 4176475 YP_664718.1 CDS omp12 fragment 3 NC_008229.1 824724 824933 R hypothetical protein complement(824724..824933) Helicobacter acinonychis str. Sheeba 4176474 YP_664719.1 CDS omp12 fragment 2 NC_008229.1 825081 825230 R hypothetical protein complement(825081..825230) Helicobacter acinonychis str. Sheeba 4176473 YP_664720.1 CDS omp12 fragment 1 NC_008229.1 825227 825721 R hypothetical protein complement(825227..825721) Helicobacter acinonychis str. Sheeba 4176472 YP_664721.1 CDS dcuA NC_008229.1 826296 827624 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(826296..827624) Helicobacter acinonychis str. Sheeba 4176409 YP_664722.1 CDS ansB NC_008229.1 827703 828755 D Probable L-asparaginase (EC 3.5.1.1) (L-asparagine amidohydrolase) (L-ASNase); High confidence in function and specificity; L-asparaginase II 827703..828755 Helicobacter acinonychis str. Sheeba 4176929 YP_664723.1 CDS Hac_0949 NC_008229.1 828979 829479 R acetone carboxylase gamma subunit; Function unclear; hypothetical protein complement(828979..829479) Helicobacter acinonychis str. Sheeba 4176290 YP_664724.1 CDS hyuB NC_008229.1 829508 831805 R High confidence in function and specificity; N-methylhydantoinase B complement(829508..831805) Helicobacter acinonychis str. Sheeba 4177675 YP_664725.1 CDS hyuA NC_008229.1 831823 833964 R Hydantoin utilization protein A (ORF2); High confidence in function and specificity; N-methylhydantoinase A complement(831823..833964) Helicobacter acinonychis str. Sheeba 4177674 YP_664726.1 CDS Hac_0953 NC_008229.1 834199 835197 R Function unclear; outer membrane protein complement(834199..835197) Helicobacter acinonychis str. Sheeba 4176291 YP_664727.1 CDS atoE NC_008229.1 835332 836696 R Short-chain fatty acids transporter; High confidence in function and specificity; short-chain fatty acids transporter complement(835332..836696) Helicobacter acinonychis str. Sheeba 4176945 YP_664728.1 CDS scoB NC_008229.1 836719 837342 R Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5) (Succinyl CoA:3-oxoacid CoA-transferase) (OXCT B); High confidence in function and specificity; 3-oxoacid CoA-transferase subunit B complement(836719..837342) Helicobacter acinonychis str. Sheeba 4177164 YP_664729.1 CDS scoA NC_008229.1 837339 838037 R Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) (Succinyl CoA:3-oxoacid CoA-transferase) (OXCT A); High confidence in function and specificity; 3-oxoacid CoA-transferase subunit A complement(837339..838037) Helicobacter acinonychis str. Sheeba 4177163 YP_664730.1 CDS atoB NC_008229.1 838048 839223 R Acetyl-CoA acetyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase); High confidence in function and specificity; hypothetical protein complement(838048..839223) Helicobacter acinonychis str. Sheeba 4176944 YP_664731.1 CDS Hac_0959 NC_008229.1 839490 840518 D hypothetical protein 839490..840518 Helicobacter acinonychis str. Sheeba 4176292 YP_664732.1 CDS dgkA NC_008229.1 840511 840897 D Diacylglycerol kinase (EC 2.7.1.107) (DAGK) (Diglyceride kinase) (DGK); High confidence in function and specificity; hypothetical protein 840511..840897 Helicobacter acinonychis str. Sheeba 4177128 YP_664733.1 CDS gyrA NC_008229.1 840917 843412 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 840917..843412 Helicobacter acinonychis str. Sheeba 4177277 YP_664734.1 CDS Hac_0962 NC_008229.1 843412 843885 D hypothetical protein 843412..843885 Helicobacter acinonychis str. Sheeba 4176293 YP_664735.1 CDS Hac_0963 NC_008229.1 843882 845027 D High confidence in function and specificity; response regulator 843882..845027 Helicobacter acinonychis str. Sheeba 4176294 YP_664736.1 CDS Hac_0965 NC_008229.1 845306 845665 D hypothetical protein 845306..845665 Helicobacter acinonychis str. Sheeba 4176295 YP_664737.1 CDS Hac_0966 NC_008229.1 846004 846537 R High confidence in function and specificity; methylase complement(846004..846537) Helicobacter acinonychis str. Sheeba 4176296 YP_664738.1 CDS lepA NC_008229.1 846546 848360 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(846546..848360) Helicobacter acinonychis str. Sheeba 4176139 YP_664739.1 CDS dxs NC_008229.1 848357 850207 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(848357..850207) Helicobacter acinonychis str. Sheeba 4176388 YP_664740.1 CDS fliH NC_008229.1 850210 850962 R binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H complement(850210..850962) Helicobacter acinonychis str. Sheeba 4177498 YP_664741.1 CDS fliG NC_008229.1 850973 852004 R One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G complement(850973..852004) Helicobacter acinonychis str. Sheeba 4177497 YP_664742.1 CDS fliF NC_008229.1 852044 853747 R the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein complement(852044..853747) Helicobacter acinonychis str. Sheeba 4177496 YP_664743.1 CDS Hac_0972 NC_008229.1 853796 854464 R Function unclear; hypothetical protein complement(853796..854464) Helicobacter acinonychis str. Sheeba 4176908 YP_664744.1 CDS pyrG NC_008229.1 854746 856362 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 854746..856362 Helicobacter acinonychis str. Sheeba 4177755 YP_664745.1 CDS recJ NC_008229.1 856371 857921 D Single-stranded-DNA-specific exonuclease recJ (EC 3.1.-.-); High confidence in function and specificity; ssDNA-binding protein 856371..857921 Helicobacter acinonychis str. Sheeba 4177070 YP_664746.1 CDS Hac_0975 NC_008229.1 857921 858802 D Hypothetical pseudouridine synthase JHP0321 (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase); High confidence in function and specificity; ribosomal pseudouridine synthase 857921..858802 Helicobacter acinonychis str. Sheeba 4176909 YP_664747.1 CDS Hac_0976 NC_008229.1 858811 860022 R Region start changed from 859755 to 860022 (267 bases); hypothetical protein complement(858811..860022) Helicobacter acinonychis str. Sheeba 4176910 YP_664748.1 CDS Hac_0977 NC_008229.1 860019 860804 R hypothetical protein complement(860019..860804) Helicobacter acinonychis str. Sheeba 4176911 YP_664749.1 CDS fragment 2 NC_008229.1 860782 861024 R Function unclear; hypothetical protein complement(860782..861024) Helicobacter acinonychis str. Sheeba 4177026 YP_664750.1 CDS fragment 1 NC_008229.1 861030 861194 R Function unclear; hypothetical protein complement(861030..861194) Helicobacter acinonychis str. Sheeba 4177046 YP_664751.1 CDS Hac_0981 NC_008229.1 861503 861661 D hypothetical protein 861503..861661 Helicobacter acinonychis str. Sheeba 4176912 YP_664752.1 CDS Hac_0982 NC_008229.1 861877 862419 R hypothetical protein complement(861877..862419) Helicobacter acinonychis str. Sheeba 4176913 YP_664753.1 CDS Hac_0983 NC_008229.1 862421 862759 R Function unclear; hypothetical protein complement(862421..862759) Helicobacter acinonychis str. Sheeba 4176914 YP_664754.1 CDS Hac_0984 NC_008229.1 862876 863505 R beta-lactamase hcpC precursor (EC 3.5.2.6) (Cysteine-rich protein C); Specificity unclear; hypothetical protein complement(862876..863505) Helicobacter acinonychis str. Sheeba 4176915 YP_664755.1 CDS Hac_0986 NC_008229.1 863758 864162 R similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein complement(863758..864162) Helicobacter acinonychis str. Sheeba 4176916 YP_664756.1 CDS dprA NC_008229.1 864159 864959 R High confidence in function and specificity; DNA processing protein DprA complement(864159..864959) Helicobacter acinonychis str. Sheeba 4176383 YP_664757.1 CDS minE NC_008229.1 864966 865199 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(864966..865199) Helicobacter acinonychis str. Sheeba 4176769 YP_664758.1 CDS minD NC_008229.1 865196 866002 R Septum site-determining protein minD (Cell division inhibitor minD); High confidence in function and specificity; cell division inhibitor complement(865196..866002) Helicobacter acinonychis str. Sheeba 4176768 YP_664759.1 CDS ilvC NC_008229.1 866025 867017 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(866025..867017) Helicobacter acinonychis str. Sheeba 4177678 YP_664760.1 CDS nadE NC_008229.1 867273 868055 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 867273..868055 Helicobacter acinonychis str. Sheeba 4177665 YP_664761.1 CDS lpxK NC_008229.1 868052 868990 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 868052..868990 Helicobacter acinonychis str. Sheeba 4177624 YP_664762.1 CDS flaG NC_008229.1 868923 869465 R Function unclear; flagellar protein G complement(868923..869465) Helicobacter acinonychis str. Sheeba 4176828 YP_664763.1 CDS neuA fragment 2 NC_008229.1 869462 870313 R neuA; CMP-N-acetylneuraminic acid synthetase [EC:2.7.7.43]; High confidence in function and specificity; CMP-N-acetylneuraminic acid synthetase fragment 2 complement(869462..870313) Helicobacter acinonychis str. Sheeba 4177441 YP_664764.1 CDS neuA fragment 1 NC_008229.1 870319 871008 R Acylneuraminate cytidylyltransferase (EC 2.7.7.43) (CMP-N-acetylneuraminic acid synthetase) (CMP-NeuNAc synthetase) (CMP-sialic acid synthetase); High confidence in function and specificity; CMP-N-acetylneuraminic acid synthetase fragment 1 complement(870319..871008) Helicobacter acinonychis str. Sheeba 4177440 YP_664765.1 CDS flgH NC_008229.1 871032 871730 R part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein complement(871032..871730) Helicobacter acinonychis str. Sheeba 4177248 YP_664766.1 CDS omp13 NC_008229.1 871856 872596 D outer membrane protein 13 871856..872596 Helicobacter acinonychis str. Sheeba 4176477 YP_664767.1 CDS Hac_0998 NC_008229.1 872603 873145 R membrane-associated cation-independent thermostable nuclease; preferentially cleaves ss-DNA; involved in DNA transformation; nuclease NucT complement(872603..873145) Helicobacter acinonychis str. Sheeba 4176917 YP_664768.1 CDS Hac_0999 NC_008229.1 873254 874555 D hypothetical protein 873254..874555 Helicobacter acinonychis str. Sheeba 4176918 YP_664769.1 CDS gmk NC_008229.1 874566 875168 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 874566..875168 Helicobacter acinonychis str. Sheeba 4177268 YP_664770.1 CDS Hac_1001 NC_008229.1 875239 875478 D Sec-independent protein translocase protein tatA/E homolog; High confidence in function and specificity; sec-independent protein translocase protein 875239..875478 Helicobacter acinonychis str. Sheeba 4176919 YP_664771.1 CDS argS NC_008229.1 875481 877106 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 875481..877106 Helicobacter acinonychis str. Sheeba 4176931 YP_664772.1 CDS Hac_1003 NC_008229.1 877313 878068 D Specificity unclear; hypothetical protein 877313..878068 Helicobacter acinonychis str. Sheeba 4176920 YP_664773.1 CDS omp14 fragment 1 NC_008229.1 878629 879066 D hypothetical protein 878629..879066 Helicobacter acinonychis str. Sheeba 4176478 YP_664774.1 CDS omp14 fragment 2 NC_008229.1 879682 879912 D hypothetical protein 879682..879912 Helicobacter acinonychis str. Sheeba 4176479 YP_664775.1 CDS narK fragment 1 NC_008229.1 880409 880993 D nitrite extrusion protein (narK); Function unclear; nitrite extrusion protein fragment 1 880409..880993 Helicobacter acinonychis str. Sheeba 4177668 YP_664776.1 CDS narK fragment 2 NC_008229.1 881001 881555 D nitrite extrusion protein (narK); Function unclear; nitrite extrusion protein fragment 2 881001..881555 Helicobacter acinonychis str. Sheeba 4177669 YP_664777.1 CDS Hac_1014 NC_008229.1 881745 882722 R cobalamin synthesis protein/P47K family protein; Specificity unclear; cobalamin synthesis protein complement(881745..882722) Helicobacter acinonychis str. Sheeba 4176921 YP_664778.1 CDS Hac_1015 NC_008229.1 882722 883084 R hypothetical protein complement(882722..883084) Helicobacter acinonychis str. Sheeba 4176922 YP_664779.1 CDS Hac_1016 NC_008229.1 883248 884372 D High confidence in function and specificity; hypothetical protein 883248..884372 Helicobacter acinonychis str. Sheeba 4176923 YP_664780.1 CDS Hac_1017 NC_008229.1 884369 885061 D High confidence in function and specificity; restriction endonuclease 884369..885061 Helicobacter acinonychis str. Sheeba 4176924 YP_664781.1 CDS Hac_1018 NC_008229.1 885102 885983 R High confidence in function and specificity; polysaccharide deacetylase complement(885102..885983) Helicobacter acinonychis str. Sheeba 4176925 YP_664782.1 CDS Hac_1019 NC_008229.1 885996 886829 R High confidence in function and specificity; hypothetical protein complement(885996..886829) Helicobacter acinonychis str. Sheeba 4176926 YP_664783.1 CDS Hac_1020 NC_008229.1 886996 887388 R hypothetical protein complement(886996..887388) Helicobacter acinonychis str. Sheeba 4177592 YP_664784.1 CDS Hac_1021 NC_008229.1 887401 887661 R hypothetical protein complement(887401..887661) Helicobacter acinonychis str. Sheeba 4177593 YP_664785.1 CDS hemL NC_008229.1 887666 888958 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(887666..888958) Helicobacter acinonychis str. Sheeba 4177428 YP_664786.1 CDS Hac_1023 NC_008229.1 888968 889522 R hypothetical protein complement(888968..889522) Helicobacter acinonychis str. Sheeba 4177594 YP_664787.1 CDS Hac_1024 NC_008229.1 889650 890663 R hypothetical protein complement(889650..890663) Helicobacter acinonychis str. Sheeba 4177595 YP_664788.1 CDS Hac_1025 NC_008229.1 890673 891125 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(890673..891125) Helicobacter acinonychis str. Sheeba 4177596 YP_664789.1 CDS accD NC_008229.1 891139 892008 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(891139..892008) Helicobacter acinonychis str. Sheeba 4177693 YP_664790.1 CDS Hac_1027 NC_008229.1 892092 892706 D recombination protein RecO 892092..892706 Helicobacter acinonychis str. Sheeba 4177597 YP_664791.1 CDS Hac_1028 NC_008229.1 892717 893373 D High confidence in function and specificity; hypothetical protein 892717..893373 Helicobacter acinonychis str. Sheeba 4177598 YP_664792.1 CDS Hac_1029 NC_008229.1 893375 893941 R hypothetical protein complement(893375..893941) Helicobacter acinonychis str. Sheeba 4177599 YP_664793.1 CDS Hac_1030 NC_008229.1 893999 894631 R NAD(P)H nitroreductase (EC 1.-.-.-); High confidence in function and specificity; oxygen-insensitive NADPH nitroreductase complement(893999..894631) Helicobacter acinonychis str. Sheeba 4177600 YP_664794.1 CDS lgt NC_008229.1 894631 895482 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(894631..895482) Helicobacter acinonychis str. Sheeba 4177614 YP_664795.1 CDS rluA NC_008229.1 895491 896219 R High confidence in function and specificity; ribosomal pseudouridine synthase complement(895491..896219) Helicobacter acinonychis str. Sheeba 4177093 YP_664796.1 CDS kdtA NC_008229.1 896237 897373 R catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(896237..897373) Helicobacter acinonychis str. Sheeba 4176134 YP_664797.1 CDS Hac_1034 NC_008229.1 897419 898183 R Specificity unclear; hypothetical protein complement(897419..898183) Helicobacter acinonychis str. Sheeba 4177601 YP_664798.1 CDS Hac_1035 NC_008229.1 898193 898924 R High confidence in function and specificity; hypothetical protein complement(898193..898924) Helicobacter acinonychis str. Sheeba 4177602 YP_664799.1 CDS glyQ NC_008229.1 898926 899822 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(898926..899822) Helicobacter acinonychis str. Sheeba 4177264 YP_664800.1 CDS gpsA NC_008229.1 899833 900771 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(899833..900771) Helicobacter acinonychis str. Sheeba 4177269 YP_664801.1 CDS fragment 3 NC_008229.1 901295 901600 R Function unclear; hypothetical protein complement(901295..901600) Helicobacter acinonychis str. Sheeba 4177287 YP_664802.1 CDS fragment 2 NC_008229.1 901658 902173 R Function unclear; hypothetical protein complement(901658..902173) Helicobacter acinonychis str. Sheeba 4177027 YP_664803.1 CDS fragment 1 NC_008229.1 902136 902609 R Function unclear; hypothetical protein complement(902136..902609) Helicobacter acinonychis str. Sheeba 4177047 YP_664804.1 CDS fragment 3 NC_008229.1 902641 902934 R hypothetical protein complement(902641..902934) Helicobacter acinonychis str. Sheeba 4177288 YP_664805.1 CDS fragment 2 NC_008229.1 902921 903118 R hypothetical protein complement(902921..903118) Helicobacter acinonychis str. Sheeba 4177028 YP_664806.1 CDS fragment 1 NC_008229.1 903147 903389 R hypothetical protein complement(903147..903389) Helicobacter acinonychis str. Sheeba 4177048 YP_664807.1 CDS fragment 4 NC_008229.1 903422 903931 R Function unclear; hypothetical protein complement(903422..903931) Helicobacter acinonychis str. Sheeba 4176512 YP_664808.1 CDS fragment 3 NC_008229.1 903954 904256 R Function unclear; hypothetical protein complement(903954..904256) Helicobacter acinonychis str. Sheeba 4177289 YP_664809.1 CDS fragment 2 NC_008229.1 904301 904417 R hypothetical protein complement(904301..904417) Helicobacter acinonychis str. Sheeba 4177029 YP_664810.1 CDS fragment 1 NC_008229.1 904443 904874 R Specificity unclear; hypothetical protein complement(904443..904874) Helicobacter acinonychis str. Sheeba 4177049 YP_664811.1 CDS fragment 4 NC_008229.1 904939 905076 R Function unclear; hypothetical protein complement(904939..905076) Helicobacter acinonychis str. Sheeba 4176513 YP_664812.1 CDS fragment 3 NC_008229.1 905092 905184 R hypothetical protein complement(905092..905184) Helicobacter acinonychis str. Sheeba 4177290 YP_664813.1 CDS fragment 2 NC_008229.1 905352 905909 R Function unclear; hypothetical protein complement(905352..905909) Helicobacter acinonychis str. Sheeba 4177030 YP_664814.1 CDS fragment 1 NC_008229.1 906177 906281 R hypothetical protein complement(906177..906281) Helicobacter acinonychis str. Sheeba 4177050 YP_664815.1 CDS vapD NC_008229.1 906507 906743 R (O25620) Virulence-associated protein D homolog; High confidence in function and specificity; virulence associated protein D complement(906507..906743) Helicobacter acinonychis str. Sheeba 4176631 YP_664816.1 CDS Hac_1053 NC_008229.1 906863 907144 R hypothetical protein complement(906863..907144) Helicobacter acinonychis str. Sheeba 4177603 YP_664817.1 CDS Hac_1054 NC_008229.1 907161 910220 R (P94177) Cation efflux system protein czcA; High confidence in function and specificity; heavy metal cation efflux protein complement(907161..910220) Helicobacter acinonychis str. Sheeba 4177604 YP_664818.1 CDS nccB NC_008229.1 910220 911284 R (Q44585) Nickel-cobalt-cadmium resistance protein nccB; Function unclear; cobalt-zinc-cadmium resistance protein complement(910220..911284) Helicobacter acinonychis str. Sheeba 4177437 YP_664819.1 CDS Hac_1056 NC_008229.1 911281 912588 R nickel cobalt outer membrane efflux protein complement(911281..912588) Helicobacter acinonychis str. Sheeba 4177605 YP_664820.1 CDS glyS NC_008229.1 912578 914695 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(912578..914695) Helicobacter acinonychis str. Sheeba 4177265 YP_664821.1 CDS Hac_1058 NC_008229.1 914810 915850 D High confidence in function and specificity; hypothetical protein 914810..915850 Helicobacter acinonychis str. Sheeba 4177606 YP_664822.1 CDS pgm NC_008229.1 915861 917339 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 915861..917339 Helicobacter acinonychis str. Sheeba 4176775 YP_664823.1 CDS gatC NC_008229.1 917354 917632 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 917354..917632 Helicobacter acinonychis str. Sheeba 4177758 YP_664824.1 CDS pfr NC_008229.1 917994 918497 D High confidence in function and specificity; ferritin 917994..918497 Helicobacter acinonychis str. Sheeba 4176752 YP_664825.1 CDS serB NC_008229.1 918513 919136 D (P44997) Phosphoserine phosphatase (EC 3.1.3.3) (PSP) (O-phosphoserine phosphohydrolase) (PSPase); High confidence in function and specificity; hypothetical protein 918513..919136 Helicobacter acinonychis str. Sheeba 4177176 YP_664826.1 CDS fuc NC_008229.1 919306 920679 D fucosyltransferase 919306..920679 Helicobacter acinonychis str. Sheeba 4177009 YP_664827.1 CDS Hac_1064 NC_008229.1 920689 921279 R (P32849) DNA repair protein RAD5; Function unclear; hypothetical protein complement(920689..921279) Helicobacter acinonychis str. Sheeba 4177607 YP_664828.1 CDS aspA NC_008229.1 921324 922730 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(921324..922730) Helicobacter acinonychis str. Sheeba 4176940 YP_664829.1 CDS mur NC_008229.1 922785 924053 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(922785..924053) Helicobacter acinonychis str. Sheeba 4176732 YP_664830.1 CDS Hac_1067 NC_008229.1 924056 924463 R hypothetical protein complement(924056..924463) Helicobacter acinonychis str. Sheeba 4177608 YP_664831.1 CDS galU NC_008229.1 924474 925295 R (Q9I291) UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (Alpha-D-glucosyl-1-phosphate uridylyltransferase) (Uridine diphosphoglucose pyrophosphorylase); High confidence in function and specificity; UTP-glucose-1-phosphate uridylyltransferase complement(924474..925295) Helicobacter acinonychis str. Sheeba 4177021 YP_664832.1 CDS slt NC_008229.1 925292 926971 R High confidence in function and specificity; lytic murein transglycosylase complement(925292..926971) Helicobacter acinonychis str. Sheeba 4177179 YP_664833.1 CDS Hac_1070 NC_008229.1 926980 927273 R Function unclear; hypothetical protein complement(926980..927273) Helicobacter acinonychis str. Sheeba 4177609 YP_664834.1 CDS gltX NC_008229.1 927270 928589 R charges one glutamine molecule and pairs it with tRNA(Gln); glutamylglutaminyl-tRNA synthetase complement(927270..928589) Helicobacter acinonychis str. Sheeba 4177262 YP_664835.1 CDS omp15 NC_008229.1 928859 929962 D outer membrane protein 15 928859..929962 Helicobacter acinonychis str. Sheeba 4176480 YP_664836.1 CDS rfaC NC_008229.1 930001 930849 D Function unclear; hypothetical protein 930001..930849 Helicobacter acinonychis str. Sheeba 4177078 YP_664837.1 CDS typA NC_008229.1 930895 932694 D (O25225) GTP-binding protein TypA/BipA homolog; High confidence in function and specificity; GTP-binding protein TYPA/BIPA-like protein 930895..932694 Helicobacter acinonychis str. Sheeba 4176677 YP_664838.1 CDS MFOKI NC_008229.1 932710 933639 D (P29347) Modification methylase StsI (EC 2.1.1.72) (Adenine-specific methyltransferase StsI) (M.StsI); High confidence in function and specificity; site-specific type II DNA methyltransferase 932710..933639 Helicobacter acinonychis str. Sheeba 4176765 YP_664839.1 CDS Hac_1076 NC_008229.1 933622 934314 R High confidence in function and specificity; hypothetical protein complement(933622..934314) Helicobacter acinonychis str. Sheeba 4177610 YP_664840.1 CDS Hac_1077 NC_008229.1 934315 934917 R (Q9ZKR8) Hypothetical protein JHP0867; High confidence in function and specificity; hypothetical protein complement(934315..934917) Helicobacter acinonychis str. Sheeba 4177611 YP_664841.1 CDS Hac_1078 NC_008229.1 934921 935139 R hypothetical protein complement(934921..935139) Helicobacter acinonychis str. Sheeba 4176985 YP_664842.1 CDS amiF NC_008229.1 935316 936320 D formamide amidohydrolase; catalyzes the hydrolysis of formamide to formate; formamidase 935316..936320 Helicobacter acinonychis str. Sheeba 4177704 YP_664843.1 CDS homA NC_008229.1 936825 937289 R hom family outer membrane protein complement(936825..937289) Helicobacter acinonychis str. Sheeba 4176875 YP_664844.1 CDS Hac_1081 NC_008229.1 937515 938000 R High confidence in function and specificity; hypothetical protein complement(937515..938000) Helicobacter acinonychis str. Sheeba 4176986 YP_664845.1 CDS Hac_1082 NC_008229.1 938105 938860 R Specificity unclear; hypothetical protein complement(938105..938860) Helicobacter acinonychis str. Sheeba 4176987 YP_664846.1 CDS Hac_1083 NC_008229.1 938861 939463 R (Q9ZKR8) Hypothetical protein JHP0867; High confidence in function and specificity; hypothetical protein complement(938861..939463) Helicobacter acinonychis str. Sheeba 4176988 YP_664847.1 CDS Hac_1084 NC_008229.1 939467 940126 R hypothetical protein complement(939467..940126) Helicobacter acinonychis str. Sheeba 4176989 YP_664848.1 CDS surE NC_008229.1 940123 940926 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(940123..940926) Helicobacter acinonychis str. Sheeba 4177464 YP_664849.1 CDS ispA NC_008229.1 940923 941834 R (P34802) Geranylgeranyl pyrophosphate synthetase chloroplast precursor (GGPP synthetase) (GGPS) [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)]; High confidence in function and specificity; geranyltranstransferase complement(940923..941834) Helicobacter acinonychis str. Sheeba 4176128 YP_664850.1 CDS folE NC_008229.1 941850 942392 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(941850..942392) Helicobacter acinonychis str. Sheeba 4177511 YP_664851.1 CDS htpX NC_008229.1 942393 943322 R metalloprotease; heat shock protein HtpX complement(942393..943322) Helicobacter acinonychis str. Sheeba 4177544 YP_664852.1 CDS truD NC_008229.1 943312 944457 R catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D complement(943312..944457) Helicobacter acinonychis str. Sheeba 4176990 YP_664853.1 CDS recR NC_008229.1 944454 945035 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(944454..945035) Helicobacter acinonychis str. Sheeba 4177072 YP_664854.1 CDS Hac_1091 NC_008229.1 945245 945361 D (Q9ZKS7) Probable tautomerase JHP0858 (EC 5.3.2.-); hypothetical protein; tautomerase 945245..945361 Helicobacter acinonychis str. Sheeba 4176991 YP_664855.1 CDS omp16 NC_008229.1 945421 946524 R outer membrane protein 16 complement(945421..946524) Helicobacter acinonychis str. Sheeba 4176481 YP_664856.1 CDS gltX NC_008229.1 946644 948035 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 946644..948035 Helicobacter acinonychis str. Sheeba 4177260 YP_664857.1 CDS fragment 1 NC_008229.1 948061 948387 D hypothetical protein 948061..948387 Helicobacter acinonychis str. Sheeba 4177051 YP_664858.1 CDS fragment 2 NC_008229.1 948600 949283 D hypothetical protein 948600..949283 Helicobacter acinonychis str. Sheeba 4177031 YP_664859.1 CDS omp17 NC_008229.1 949276 949836 D outer membrane protein 17 949276..949836 Helicobacter acinonychis str. Sheeba 4176482 YP_664860.1 CDS kefB NC_008229.1 950187 951437 D (Q8XA20) Glutathione-regulated potassium-efflux system protein kefC (K(+)/H(+) antiporter); High confidence in function and specificity; glutathione-regulated potassium-efflux system protein 950187..951437 Helicobacter acinonychis str. Sheeba 4176136 YP_664861.1 CDS pepF NC_008229.1 951538 953274 D (P94876) Oligoendopeptidase F chromosomal (EC 3.4.24.-); High confidence in function and specificity; hypothetical protein 951538..953274 Helicobacter acinonychis str. Sheeba 4176745 YP_664862.1 CDS Hac_1099 NC_008229.1 953259 953747 D hypothetical protein 953259..953747 Helicobacter acinonychis str. Sheeba 4176992 YP_664863.1 CDS Hac_1100 NC_008229.1 953759 955246 D hypothetical protein 953759..955246 Helicobacter acinonychis str. Sheeba 4176993 YP_664864.1 CDS Hac_1101 NC_008229.1 955248 955562 D hypothetical protein 955248..955562 Helicobacter acinonychis str. Sheeba 4176994 YP_664865.1 CDS Hac_1102 NC_008229.1 955572 956342 D hypothetical protein 955572..956342 Helicobacter acinonychis str. Sheeba 4176995 YP_664866.1 CDS Hac_1103 NC_008229.1 956644 956961 D hypothetical protein 956644..956961 Helicobacter acinonychis str. Sheeba 4176996 YP_664867.1 CDS Hac_1106 NC_008229.1 957067 958962 D Function unclear; hypothetical protein 957067..958962 Helicobacter acinonychis str. Sheeba 4176997 YP_664868.1 CDS hsdR fragment 1 NC_008229.1 959011 959349 D ); Function unclear; type I restriction enzyme R protein fragment 1 959011..959349 Helicobacter acinonychis str. Sheeba 4177535 YP_664869.1 CDS hsdR fragment 2 NC_008229.1 959374 959688 D Function unclear; type I restriction enzyme R protein fragment 2 959374..959688 Helicobacter acinonychis str. Sheeba 4177536 YP_664870.1 CDS hsdR fragment 3 NC_008229.1 959859 961229 D (Q60295) type I restriction enzyme MjaXP R protein (EC 3.1.21.3); Function unclear; type I restriction enzyme R protein fragment 3 959859..961229 Helicobacter acinonychis str. Sheeba 4177537 YP_664871.1 CDS hsdR fragment 4 NC_008229.1 961213 962142 D High confidence in function and specificity; type I restriction enzyme R protein fragment 4 961213..962142 Helicobacter acinonychis str. Sheeba 4177538 YP_664872.1 CDS hsdM NC_008229.1 962132 963763 D (Q47163) Type I restriction enzyme EcoprrI M protein (EC 2.1.1.72) (M.EcoprrI); High confidence in function and specificity; type I restriction enzyme M protein 962132..963763 Helicobacter acinonychis str. Sheeba 4177534 YP_664873.1 CDS Hac_1112 NC_008229.1 963768 964025 D hypothetical protein 963768..964025 Helicobacter acinonychis str. Sheeba 4176998 YP_664874.1 CDS hsdS NC_008229.1 964109 964882 D (Q60296) type I restriction enzyme MjaXP specificity protein (S protein) (S.MjaXP); High confidence in function and specificity; type I restriction-modification enzyme, S subunit 964109..964882 Helicobacter acinonychis str. Sheeba 4177539 YP_664875.1 CDS ppk NC_008229.1 965112 967136 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 965112..967136 Helicobacter acinonychis str. Sheeba 4176554 YP_664876.1 CDS pyrD NC_008229.1 967173 968228 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 967173..968228 Helicobacter acinonychis str. Sheeba 4177752 YP_664877.1 CDS pqqE NC_008229.1 968225 969559 D (P55679) Hypothetical zinc protease y4wA (EC 3.4.99.-); High confidence in function and specificity; zinc protease 968225..969559 Helicobacter acinonychis str. Sheeba 4176558 YP_664878.1 CDS dapA NC_008229.1 969577 970479 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 969577..970479 Helicobacter acinonychis str. Sheeba 4176401 YP_664879.1 CDS hdhA NC_008229.1 970476 971264 D Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 970476..971264 Helicobacter acinonychis str. Sheeba 4177420 YP_664880.1 CDS Hac_1119 NC_008229.1 971274 971882 D hypothetical protein 971274..971882 Helicobacter acinonychis str. Sheeba 4176999 YP_664881.1 CDS pgsA NC_008229.1 971879 972418 D (P46322) CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase) (PGP synthase); Function unclear; hypothetical protein 971879..972418 Helicobacter acinonychis str. Sheeba 4176777 YP_664882.1 CDS rocE NC_008229.1 972694 974136 D (Q47689) Probable S-methylmethionine permease; High confidence in function and specificity; amino acid permease 972694..974136 Helicobacter acinonychis str. Sheeba 4177098 YP_664883.1 CDS htrA NC_008229.1 974183 975613 D High confidence in function and specificity; serine protease 974183..975613 Helicobacter acinonychis str. Sheeba 4177545 YP_664884.1 CDS ispDF NC_008229.1 975632 976852 D bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein 975632..976852 Helicobacter acinonychis str. Sheeba 4176130 YP_664885.1 CDS Hac_1125 NC_008229.1 976874 977770 D (P45337) Transcriptional regulatory protein qseB; Specificity unclear; two component response regulator 976874..977770 Helicobacter acinonychis str. Sheeba 4177000 YP_664886.1 CDS polA NC_008229.1 977903 978727 D (Q9KAV6) Probable 5-3 exonuclease (EC 3.1.11.-); Function unclear; DNA polymerase I 977903..978727 Helicobacter acinonychis str. Sheeba 4176787 YP_664887.1 CDS Hac_1127 NC_008229.1 978990 980240 R hypothetical protein complement(978990..980240) Helicobacter acinonychis str. Sheeba 4177001 YP_664888.1 CDS cbpA NC_008229.1 980408 981271 D High confidence in function and specificity; co-chaperone-curved DNA binding protein A 980408..981271 Helicobacter acinonychis str. Sheeba 4176592 YP_664889.1 CDS hspR NC_008229.1 981281 981652 D (P45277) HTH-type transcriptional regulator zntR homolog; High confidence in function and specificity; heat shock transcriptional regulator 981281..981652 Helicobacter acinonychis str. Sheeba 4177542 YP_664890.1 CDS Hac_1130 NC_008229.1 981649 982830 D (Q9WYX8) Hypothetical protein TM0508; Specificity unclear; recombination factor protein RarA 981649..982830 Helicobacter acinonychis str. Sheeba 4177002 YP_664891.1 CDS fur NC_008229.1 982985 983437 D (Q9ZM26) Ferric uptake regulation protein (Ferric uptake regulator); High confidence in function and specificity; ferric uptake regulation protein 982985..983437 Helicobacter acinonychis str. Sheeba 4177018 YP_664892.1 CDS Hac_1132 NC_008229.1 983447 983953 R Function unclear; hypothetical protein complement(983447..983953) Helicobacter acinonychis str. Sheeba 4177003 YP_664893.1 CDS Hac_1133 NC_008229.1 983950 984486 R (P37673) Hypothetical protein yiaL; Function unclear; hypothetical protein complement(983950..984486) Helicobacter acinonychis str. Sheeba 4176965 YP_664894.1 CDS fliY NC_008229.1 984516 985367 R One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliY complement(984516..985367) Helicobacter acinonychis str. Sheeba 4177506 YP_664895.1 CDS fliM NC_008229.1 985371 986435 R with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM complement(985371..986435) Helicobacter acinonychis str. Sheeba 4177501 YP_664896.1 CDS fliA NC_008229.1 986428 987204 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(986428..987204) Helicobacter acinonychis str. Sheeba 4177256 YP_664897.1 CDS Hac_1137 NC_008229.1 987182 987496 R hypothetical protein complement(987182..987496) Helicobacter acinonychis str. Sheeba 4176966 YP_664898.1 CDS Hac_1138 NC_008229.1 987501 988385 R flagellar biosynthesis switch protein; High confidence in function and specificity; ATP-binding protein complement(987501..988385) Helicobacter acinonychis str. Sheeba 4176967 YP_664899.1 CDS flhF NC_008229.1 988382 989755 R positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF complement(988382..989755) Helicobacter acinonychis str. Sheeba 4177255 YP_664900.1 CDS folK NC_008229.1 989752 990243 R (O25680) 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) (78-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-78-dihydropterin pyrophosphokinase) (PPPK); High confidence in function and specificity; 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase complement(989752..990243) Helicobacter acinonychis str. Sheeba 4177512 YP_664901.1 CDS Hac_1141 NC_008229.1 990240 991313 R (P54518) peptidase yqhT (EC 3.4.-.-); High confidence in function and specificity; proline peptidase complement(990240..991313) Helicobacter acinonychis str. Sheeba 4176968 YP_664902.1 CDS aroQ NC_008229.1 991332 991838 R catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase complement(991332..991838) Helicobacter acinonychis str. Sheeba 4176938 YP_664903.1 CDS Hac_1143 NC_008229.1 991955 993250 R (P27243) O-antigen ligase; Function unclear; hypothetical protein complement(991955..993250) Helicobacter acinonychis str. Sheeba 4176969 YP_664904.1 CDS rpsO NC_008229.1 993306 993578 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(993306..993578) Helicobacter acinonychis str. Sheeba 4177154 YP_664905.1 CDS flhA NC_008229.1 993736 995937 D membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 993736..995937 Helicobacter acinonychis str. Sheeba 4177253 YP_664906.1 CDS Hac_1146 NC_008229.1 995957 997000 D Function unclear; hypothetical protein 995957..997000 Helicobacter acinonychis str. Sheeba 4176970 YP_664907.1 CDS omp18 fragment 4 NC_008229.1 997818 998093 R hypothetical protein complement(997818..998093) Helicobacter acinonychis str. Sheeba 4176486 YP_664908.1 CDS omp18 fragment 3 NC_008229.1 998137 998343 R hypothetical protein complement(998137..998343) Helicobacter acinonychis str. Sheeba 4176485 YP_664909.1 CDS omp18 fragment 2 NC_008229.1 998401 998769 R hypothetical protein complement(998401..998769) Helicobacter acinonychis str. Sheeba 4176484 YP_664910.1 CDS omp18 fragment 1 NC_008229.1 998820 999014 R hypothetical protein complement(998820..999014) Helicobacter acinonychis str. Sheeba 4176483 YP_664911.1 CDS Hac_1152 NC_008229.1 999013 999204 D outer membrane protein region, nucleotide level blastn; hypothetical protein; hypothetical protein 999013..999204 Helicobacter acinonychis str. Sheeba 4176971 YP_664912.1 CDS Hac_1154 NC_008229.1 999589 1000260 R (P77380) Transcriptional regulatory protein cusR; High confidence in function and specificity; two-component system regulatory protein complement(999589..1000260) Helicobacter acinonychis str. Sheeba 4176972 YP_664913.1 CDS Hac_1155 NC_008229.1 1000620 1001732 R (O25685) Hypothetical protein HP1044; High confidence in function and specificity; integral membrane protein complement(1000620..1001732) Helicobacter acinonychis str. Sheeba 4176973 YP_664914.1 CDS acoE NC_008229.1 1001939 1003927 D Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 1001939..1003927 Helicobacter acinonychis str. Sheeba 4177696 YP_664915.1 CDS Hac_1157 NC_008229.1 1003980 1004420 R (Q9ZM44) Hypothetical UPF0090 protein JHP0379; Specificity unclear; hypothetical protein complement(1003980..1004420) Helicobacter acinonychis str. Sheeba 4176974 YP_664916.1 CDS rbfA NC_008229.1 1004413 1004748 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(1004413..1004748) Helicobacter acinonychis str. Sheeba 4177065 YP_664917.1 CDS infB NC_008229.1 1004748 1007573 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(1004748..1007573) Helicobacter acinonychis str. Sheeba 4177681 YP_664918.1 CDS Hac_1160 NC_008229.1 1007570 1007797 R (O66647) Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS); Function unclear; nucleic acid binding transriptional terminator complement(1007570..1007797) Helicobacter acinonychis str. Sheeba 4176975 YP_664919.1 CDS thrB NC_008229.1 1007811 1008692 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase complement(1007811..1008692) Helicobacter acinonychis str. Sheeba 4177475 YP_664920.1 CDS Hac_1162 NC_008229.1 1008747 1009226 R (Q8RF47) Bifunctional 3-dehydroquinate synthase/phosphatase [Includes: 3-dehydroquinate synthase (EC 4.2.3.4); Unknown phosphatase (EC 3.6.1.-)]; Function unclear; hypothetical protein complement(1008747..1009226) Helicobacter acinonychis str. Sheeba 4176976 YP_664921.1 CDS lpxC NC_008229.1 1009248 1010135 R zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase complement(1009248..1010135) Helicobacter acinonychis str. Sheeba 4177622 YP_664922.1 CDS minC NC_008229.1 1010132 1010719 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1010132..1010719) Helicobacter acinonychis str. Sheeba 4176767 YP_664923.1 CDS Hac_1165 NC_008229.1 1010722 1012050 R Function unclear; metalloendopeptidase related membrane protein complement(1010722..1012050) Helicobacter acinonychis str. Sheeba 4176977 YP_664924.1 CDS Hac_1166 NC_008229.1 1012060 1013004 R (O67300) Hypothetical protein AQ_1259 precursor; hypothetical protein; hypothetical protein complement(1012060..1013004) Helicobacter acinonychis str. Sheeba 4176978 YP_664925.1 CDS Hac_1167 NC_008229.1 1013013 1013846 R hypothetical protein complement(1013013..1013846) Helicobacter acinonychis str. Sheeba 4176979 YP_664926.1 CDS Hac_1168 NC_008229.1 1013836 1014558 R hypothetical protein complement(1013836..1014558) Helicobacter acinonychis str. Sheeba 4176980 YP_664927.1 CDS panB NC_008229.1 1014706 1015518 D catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 1014706..1015518 Helicobacter acinonychis str. Sheeba 4177336 YP_664928.1 CDS ruvB NC_008229.1 1015518 1016528 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1015518..1016528 Helicobacter acinonychis str. Sheeba 4177161 YP_664929.1 CDS tatB NC_008229.1 1016596 1017063 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 1016596..1017063 Helicobacter acinonychis str. Sheeba 4177471 YP_664930.1 CDS tatC NC_008229.1 1017056 1017796 D (O25701) Sec-independent protein translocase protein tatC homolog; High confidence in function and specificity; sec-independent protein translocase 1017056..1017796 Helicobacter acinonychis str. Sheeba 4177472 YP_664931.1 CDS queA NC_008229.1 1017793 1018830 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1017793..1018830 Helicobacter acinonychis str. Sheeba 4177063 YP_664932.1 CDS gidB NC_008229.1 1018827 1019363 D glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1018827..1019363 Helicobacter acinonychis str. Sheeba 4177764 YP_664933.1 CDS Hac_1175 NC_008229.1 1019357 1019587 D hypothetical protein 1019357..1019587 Helicobacter acinonychis str. Sheeba 4176981 YP_664934.1 CDS Hac_1176 NC_008229.1 1019590 1019997 D hypothetical protein 1019590..1019997 Helicobacter acinonychis str. Sheeba 4176982 YP_664935.1 CDS omp19 NC_008229.1 1020133 1020783 R outer membrane protein 19 complement(1020133..1020783) Helicobacter acinonychis str. Sheeba 4176487 YP_664936.1 CDS cheY NC_008229.1 1021049 1021423 D (P71129) Chemotaxis protein cheY homolog; High confidence in function and specificity; CheY response regulator 1021049..1021423 Helicobacter acinonychis str. Sheeba 4176604 YP_664937.1 CDS prmA NC_008229.1 1021424 1022413 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 1021424..1022413 Helicobacter acinonychis str. Sheeba 4176562 YP_664938.1 CDS ftsH NC_008229.1 1022422 1024329 D (Q9ZM66) Cell division protein ftsH homolog (EC 3.4.24.-); High confidence in function and specificity; membrane bound zinc metallopeptidase 1022422..1024329 Helicobacter acinonychis str. Sheeba 4176528 YP_664939.1 CDS pssA NC_008229.1 1024577 1025290 D (Q9ZM68) CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) (Phosphatidylserine synthase); High confidence in function and specificity; hypothetical protein 1024577..1025290 Helicobacter acinonychis str. Sheeba 4177738 YP_664940.1 CDS copA NC_008229.1 1025287 1027512 D (Q59467) Copper-transporting ATPase (EC 3.6.3.4); High confidence in function and specificity; copper-transporting ATPase 1025287..1027512 Helicobacter acinonychis str. Sheeba 4176897 YP_664941.1 CDS copP NC_008229.1 1027513 1027713 D (Q9ZM70) COP associated protein (Copper ion binding protein); High confidence in function and specificity; copper iron binding protein 1027513..1027713 Helicobacter acinonychis str. Sheeba 4176898 YP_664942.1 CDS fragment 1 NC_008229.1 1027893 1028204 D hypothetical protein 1027893..1028204 Helicobacter acinonychis str. Sheeba 4177052 YP_664943.1 CDS fragment 2 NC_008229.1 1028206 1028487 D hypothetical protein 1028206..1028487 Helicobacter acinonychis str. Sheeba 4177032 YP_664944.1 CDS fragment 3 NC_008229.1 1028629 1028721 D hypothetical protein 1028629..1028721 Helicobacter acinonychis str. Sheeba 4177291 YP_664945.1 CDS Hac_1188 NC_008229.1 1028745 1030019 R hypothetical protein complement(1028745..1030019) Helicobacter acinonychis str. Sheeba 4176983 YP_664946.1 CDS Hac_1189 NC_008229.1 1030193 1030714 D hypothetical protein 1030193..1030714 Helicobacter acinonychis str. Sheeba 4176984 YP_664947.1 CDS Hac_1190 NC_008229.1 1030711 1031688 R Region start changed from 1031643 to 1031688 (45 bases); high-affinity nickel transport protein complement(1030711..1031688) Helicobacter acinonychis str. Sheeba 4177180 YP_664948.1 CDS Hac_1192 NC_008229.1 1031891 1032121 D hypothetical protein 1031891..1032121 Helicobacter acinonychis str. Sheeba 4177181 YP_664949.1 CDS Hac_1193 NC_008229.1 1032172 1032369 D hypothetical protein 1032172..1032369 Helicobacter acinonychis str. Sheeba 4177182 YP_664950.1 CDS Hac_1195 NC_008229.1 1032834 1033082 R HP0827: ss-DNA binding protein 12RNP2 precursor; High confidence in function and specificity; RNA-binding protein complement(1032834..1033082) Helicobacter acinonychis str. Sheeba 4177183 YP_664951.1 CDS atpB NC_008229.1 1033225 1033905 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(1033225..1033905) Helicobacter acinonychis str. Sheeba 4177103 YP_664952.1 CDS guaB NC_008229.1 1034027 1035472 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(1034027..1035472) Helicobacter acinonychis str. Sheeba 4177276 YP_664953.1 CDS gatA NC_008229.1 1035482 1036843 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(1035482..1036843) Helicobacter acinonychis str. Sheeba 4177756 YP_664954.1 CDS Hac_1199 NC_008229.1 1036910 1037086 D hypothetical protein 1036910..1037086 Helicobacter acinonychis str. Sheeba 4177184 YP_664955.1 CDS coaE NC_008229.1 1037153 1037755 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(1037153..1037755) Helicobacter acinonychis str. Sheeba 4177185 YP_664956.1 CDS speE NC_008229.1 1037757 1038545 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(1037757..1038545) Helicobacter acinonychis str. Sheeba 4177461 YP_664957.1 CDS Hac_1203 NC_008229.1 1038622 1039497 R hypothetical protein complement(1038622..1039497) Helicobacter acinonychis str. Sheeba 4177186 YP_664958.1 CDS engA NC_008229.1 1039574 1040962 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1039574..1040962 Helicobacter acinonychis str. Sheeba 4177187 YP_664959.1 CDS hupB NC_008229.1 1041103 1041387 D (Q92SJ7) Integration host factor beta-subunit (IHF-beta); High confidence in function and specificity; histon like DNA-binding protein HU 1041103..1041387 Helicobacter acinonychis str. Sheeba 4177546 YP_664960.1 CDS Hac_1207 NC_008229.1 1041845 1042450 D Function unclear; hypothetical protein 1041845..1042450 Helicobacter acinonychis str. Sheeba 4177188 YP_664961.1 CDS Hac_1208 NC_008229.1 1042470 1043087 D hypothetical protein 1042470..1043087 Helicobacter acinonychis str. Sheeba 4177189 YP_664962.1 CDS ompP1 NC_008229.1 1043084 1044850 D (P59741) Long-chain fatty acid transport protein precursor (Outer membrane fadL protein) (Outer membrane flp protein); Function unclear; outer membrane transport protein P1 1043084..1044850 Helicobacter acinonychis str. Sheeba 4176441 YP_664963.1 CDS flaA1 NC_008229.1 1044854 1045855 D (Q58461) Hypothetical protein MJ1061; High confidence in function and specificity; flagellar glycosylation protein 1044854..1045855 Helicobacter acinonychis str. Sheeba 4176825 YP_664964.1 CDS dfp NC_008229.1 1045852 1047129 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 1045852..1047129 Helicobacter acinonychis str. Sheeba 4177127 YP_664965.1 CDS Hac_1212 NC_008229.1 1047129 1047866 D hypothetical protein 1047129..1047866 Helicobacter acinonychis str. Sheeba 4177190 YP_664966.1 CDS Hac_1213 NC_008229.1 1048004 1048987 D (P08455) Modification methylase NgoPII (EC 2.1.1.37) (Cytosine-specific methyltransferase NgoPII) (M.NgoPII); High confidence in function and specificity; site-specific DNA methyltransferase 1048004..1048987 Helicobacter acinonychis str. Sheeba 4177191 YP_664967.1 CDS Hac_1214 NC_008229.1 1048984 1049937 D (O68584) Type II restriction enzyme HaeIII (EC 3.1.21.4) (Endonuclease HaeIII) (R.HaeIII); Specificity unclear; type II restriction endonuclease 1048984..1049937 Helicobacter acinonychis str. Sheeba 4177192 YP_664968.1 CDS Hac_1215 NC_008229.1 1050101 1050793 D (P75806) Hypothetical protein ybjG; Specificity unclear; hypothetical protein 1050101..1050793 Helicobacter acinonychis str. Sheeba 4177193 YP_664969.1 CDS Hac_1216 NC_008229.1 1051035 1051952 R related to restriction endonuclease-replacing gene A; Function unclear; hypothetical protein complement(1051035..1051952) Helicobacter acinonychis str. Sheeba 4177194 YP_664970.1 CDS yheS NC_008229.1 1051954 1053555 R High confidence in function and specificity; ABC transporter ATP-binding protein complement(1051954..1053555) Helicobacter acinonychis str. Sheeba 4177715 YP_664971.1 CDS algI NC_008229.1 1053704 1055203 D (Q51392) Probable poly(beta-D-mannuronate) O-acetylase (EC 2.3.1.-) (Alginate biosynthesis protein algI); High confidence in function and specificity; alginate o-acetyltransferase 1053704..1055203 Helicobacter acinonychis str. Sheeba 4177709 YP_664972.1 CDS Hac_1219 NC_008229.1 1055213 1056310 D hypothetical protein 1055213..1056310 Helicobacter acinonychis str. Sheeba 4177195 YP_664973.1 CDS gmhA NC_008229.1 1056313 1056879 R catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase complement(1056313..1056879) Helicobacter acinonychis str. Sheeba 4177267 YP_664974.1 CDS waaE NC_008229.1 1056884 1058275 R High confidence in function and specificity; ADP-heptose synthase complement(1056884..1058275) Helicobacter acinonychis str. Sheeba 4176636 YP_664975.1 CDS waaD NC_008229.1 1058272 1059264 R (P45048) ADP-L-glycero-D-manno-heptose-6-epimerase (EC 5.1.3.20) (ADP-glyceromanno-heptose 6-epimerase); High confidence in function and specificity; ADP-L-glycero-D-manno-heptose-6-epimerase complement(1058272..1059264) Helicobacter acinonychis str. Sheeba 4176635 YP_664976.1 CDS Hac_1223 NC_008229.1 1059273 1059794 R High confidence in function and specificity; histinol phosphatase complement(1059273..1059794) Helicobacter acinonychis str. Sheeba 4177196 YP_664977.1 CDS Hac_1224 NC_008229.1 1059784 1060530 R Specificity unclear; hypothetical protein complement(1059784..1060530) Helicobacter acinonychis str. Sheeba 4177197 YP_664978.1 CDS Hac_1225 NC_008229.1 1060527 1061192 R type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase complement(1060527..1061192) Helicobacter acinonychis str. Sheeba 4177198 YP_664979.1 CDS Hac_1226 NC_008229.1 1061197 1062873 R (Q83BS1) Translation initiation factor IF-2; High confidence in function and specificity; hypothetical protein complement(1061197..1062873) Helicobacter acinonychis str. Sheeba 4176257 YP_664980.1 CDS Hac_1227 NC_008229.1 1062899 1063525 R hypothetical protein complement(1062899..1063525) Helicobacter acinonychis str. Sheeba 4176258 YP_664981.1 CDS dut NC_008229.1 1063522 1063959 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(1063522..1063959) Helicobacter acinonychis str. Sheeba 4176385 YP_664982.1 CDS greA NC_008229.1 1063949 1064443 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(1063949..1064443) Helicobacter acinonychis str. Sheeba 4177271 YP_664983.1 CDS lpxB NC_008229.1 1064484 1065566 R catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; ipid-A-disaccharide synthase complement(1064484..1065566) Helicobacter acinonychis str. Sheeba 4177621 YP_664984.1 CDS Hac_1231 NC_008229.1 1065566 1066024 R Specificity unclear; hypothetical protein complement(1065566..1066024) Helicobacter acinonychis str. Sheeba 4176259 YP_664985.1 CDS hypA NC_008229.1 1066030 1066383 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein complement(1066030..1066383) Helicobacter acinonychis str. Sheeba 4177551 YP_664986.1 CDS flgE NC_008229.1 1066444 1068600 R the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE complement(1066444..1068600) Helicobacter acinonychis str. Sheeba 4177244 YP_664987.1 CDS cdh NC_008229.1 1068820 1069560 R (P06282) CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) (CDP-diacylglycerol phosphatidylhydrolase) (CDP-diglyceride hydrolase); High confidence in function and specificity; CDP-diacylglycerol pyrophosphatase complement(1068820..1069560) Helicobacter acinonychis str. Sheeba 4176595 YP_664988.1 CDS phnA NC_008229.1 1069849 1070148 D (P16680) PhnA protein; Function unclear; alkylphosphonate uptake protein 1069849..1070148 Helicobacter acinonychis str. Sheeba 4176780 YP_664989.1 CDS Hac_1237 NC_008229.1 1070187 1070402 R hypothetical protein complement(1070187..1070402) Helicobacter acinonychis str. Sheeba 4176260 YP_664990.1 CDS Hac_1238 NC_008229.1 1070470 1071345 R katA associated protein complement(1070470..1071345) Helicobacter acinonychis str. Sheeba 4176261 YP_664991.1 CDS katA NC_008229.1 1071496 1073013 R (P77872) Catalase (EC 1.11.1.6); High confidence in function and specificity; hypothetical protein complement(1071496..1073013) Helicobacter acinonychis str. Sheeba 4176131 YP_664992.1 CDS frpB NC_008229.1 1073314 1075683 D (P44523) Heme/hemopexin utilization protein C precursor; Function unclear; iron-regulated outer membrane protein 1073314..1075683 Helicobacter acinonychis str. Sheeba 4176523 YP_664993.1 CDS ruvC NC_008229.1 1075957 1076430 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(1075957..1076430) Helicobacter acinonychis str. Sheeba 4177162 YP_664994.1 CDS Hac_1243 NC_008229.1 1076563 1077294 D Function unclear; hypothetical protein 1076563..1077294 Helicobacter acinonychis str. Sheeba 4176262 YP_664995.1 CDS homB fragment 1 NC_008229.1 1077511 1077927 D hypothetical protein 1077511..1077927 Helicobacter acinonychis str. Sheeba 4176876 YP_664996.1 CDS homB fragment 2 NC_008229.1 1077959 1078885 D hypothetical protein 1077959..1078885 Helicobacter acinonychis str. Sheeba 4176877 YP_664997.1 CDS homB fragment 3 NC_008229.1 1078986 1079120 D hypothetical protein 1078986..1079120 Helicobacter acinonychis str. Sheeba 4176878 YP_664998.1 CDS homB fragment 4 NC_008229.1 1079186 1079506 D hypothetical protein 1079186..1079506 Helicobacter acinonychis str. Sheeba 4176879 YP_664999.1 CDS ruvA NC_008229.1 1079584 1080135 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(1079584..1080135) Helicobacter acinonychis str. Sheeba 4177160 YP_665000.1 CDS Hac_1249 NC_008229.1 1080166 1082001 R hypothetical protein complement(1080166..1082001) Helicobacter acinonychis str. Sheeba 4176263 YP_665001.1 CDS mviN NC_008229.1 1082095 1083555 D (O25551) Virulence factor mviN homolog; High confidence in function and specificity; virulence factor MviN 1082095..1083555 Helicobacter acinonychis str. Sheeba 4177660 YP_665002.1 CDS cysS NC_008229.1 1083556 1084953 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 1083556..1084953 Helicobacter acinonychis str. Sheeba 4176397 YP_665003.1 CDS vacA fragment 1 NC_008229.1 1085315 1085509 D (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity; vacuolating cytotoxin vacA fragment 1 1085315..1085509 Helicobacter acinonychis str. Sheeba 4176615 YP_665004.1 CDS vacA fragment 2 NC_008229.1 1085576 1085866 D (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity; vacuolating cytotoxin vacA fragment 2 1085576..1085866 Helicobacter acinonychis str. Sheeba 4176620 YP_665005.1 CDS vacA fragment 3 NC_008229.1 1085841 1086053 D (Q48258) Vacuolating cytotoxin precursor; Conserved hypothetical protein; vacuolating cytotoxin vacA fragment 3 1085841..1086053 Helicobacter acinonychis str. Sheeba 4176621 YP_665006.1 CDS vacA fragment 4 NC_008229.1 1086075 1086191 D (P55981) Vacuolating cytotoxin precursor; hypothetical protein; vacuolating cytotoxin vacA fragment 4 1086075..1086191 Helicobacter acinonychis str. Sheeba 4176622 YP_665007.1 CDS vacA fragment 5 NC_008229.1 1086204 1086419 D (Q9ZKW5) Vacuolating cytotoxin precursor; High confidence in function and specificity; vacuolating cytotoxin vacA fragment 5 1086204..1086419 Helicobacter acinonychis str. Sheeba 4176623 YP_665008.1 CDS vacA fragment 6 NC_008229.1 1086489 1086767 D (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity; vacuolating cytotoxin vacA fragment 6 1086489..1086767 Helicobacter acinonychis str. Sheeba 4176624 YP_665009.1 CDS vacA fragment 7 NC_008229.1 1086971 1087501 D (Q48247) Vacuolating cytotoxin precursor; High confidence in function and specificity; vacuolating cytotoxin vacA fragment 7 1086971..1087501 Helicobacter acinonychis str. Sheeba 4176625 YP_665010.1 CDS vacA fragment 8 NC_008229.1 1087518 1087838 D (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity; vacuolating cytotoxin VacA fragment 8 1087518..1087838 Helicobacter acinonychis str. Sheeba 4176626 YP_665011.1 CDS vacA fragment 9 NC_008229.1 1087984 1088106 D vacuolating cytotoxin vacA fragment 9 1087984..1088106 Helicobacter acinonychis str. Sheeba 4176627 YP_665012.1 CDS vacA fragment 10 NC_008229.1 1088177 1088449 D (Q48258) Vacuolating cytotoxin precursor, inactive; High confidence in function and specificity; vacuolating cytotoxin VacA fragment 10 1088177..1088449 Helicobacter acinonychis str. Sheeba 4176616 YP_665013.1 CDS vacA fragment 11 NC_008229.1 1088465 1088665 D (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity; vacuolating cytotoxin vacA fragment 11 1088465..1088665 Helicobacter acinonychis str. Sheeba 4176617 YP_665014.1 CDS vacA fragment 12 NC_008229.1 1088690 1088824 D (Q48258) Vacuolating cytotoxin precursor; hypothetical protein; vacuolating cytotoxin VacA fragment 12 1088690..1088824 Helicobacter acinonychis str. Sheeba 4176618 YP_665015.1 CDS vacA fragment 13 NC_008229.1 1088911 1089129 D (Q48253) Vacuolating cytotoxin precursor; High confidence in function and specificity; vacuolating cytotoxin VacA fragment13 1088911..1089129 Helicobacter acinonychis str. Sheeba 4176619 YP_665016.1 CDS cst NC_008229.1 1089591 1090778 R High confidence in function and specificity; bifunctional alpha-2,3/-2,8-sialyltransferase complement(1089591..1090778) Helicobacter acinonychis str. Sheeba 4176903 YP_665017.1 CDS cst NC_008229.1 1090775 1092043 R Specificity unclear; bifunctional alpha-2,3/-2,8-sialyltransferase complement(1090775..1092043) Helicobacter acinonychis str. Sheeba 4176904 YP_665018.1 CDS neuA NC_008229.1 1092030 1092689 R (Q9AFG9) Acylneuraminate cytidylyltransferase (EC 2.7.7.43) (CMP-N-acetylneuraminic acid synthetase) (CMP-NeuNAc synthetase) (CMP-sialic acid synthetase); High confidence in function and specificity; N-acylneuraminate cytidylyltransferase complement(1092030..1092689) Helicobacter acinonychis str. Sheeba 4177439 YP_665019.1 CDS neuC NC_008229.1 1092686 1093927 R High confidence in function and specificity; hypothetical protein complement(1092686..1093927) Helicobacter acinonychis str. Sheeba 4177443 YP_665020.1 CDS neuB NC_008229.1 1093937 1094974 R (Q9NR45) Sialic acid synthase (N-acetylneuraminate synthase) (EC 2.5.1.56) (N-acetylneuraminic acid synthase) (N-acetylneuraminate-9-phosphate synthase) (EC 2.5.1.57) (N-acetylneuraminic acid phosphate synthase); High confidence in function and specificity; N-acetylneuraminic acid synthetase complement(1093937..1094974) Helicobacter acinonychis str. Sheeba 4177442 YP_665021.1 CDS fecE NC_008229.1 1095108 1095875 R (O05732) Probable iron chelatin transport ATP-binding protein HP0888; High confidence in function and specificity; iron(III) dicitrate transporter ATP-binding protein complement(1095108..1095875) Helicobacter acinonychis str. Sheeba 4176815 YP_665022.1 CDS fecD NC_008229.1 1095875 1096855 R (O05731) Probable iron chelatin transport system permease HP0889; High confidence in function and specificity; iron(III) ABC transporter permease complement(1095875..1096855) Helicobacter acinonychis str. Sheeba 4176814 YP_665023.1 CDS vdlC NC_008229.1 1096855 1097691 R (Q9ZKW1) Probable short-chain type dehydrogenase/reductase vdlC (EC 1.-.-.-); High confidence in function and specificity; short chain dehydrogenase/reductase family oxidoreductase complement(1096855..1097691) Helicobacter acinonychis str. Sheeba 4176632 YP_665024.1 CDS Hac_1275 NC_008229.1 1097831 1098352 D (O05729) Protein vdlD; High confidence in function and specificity; acyl-CoA hydrolase 1097831..1098352 Helicobacter acinonychis str. Sheeba 4176264 YP_665025.1 CDS Hac_1276 NC_008229.1 1098674 1099039 R hypothetical protein complement(1098674..1099039) Helicobacter acinonychis str. Sheeba 4176265 YP_665026.1 CDS omp20 fragment 2 NC_008229.1 1099609 1099839 R hypothetical protein complement(1099609..1099839) Helicobacter acinonychis str. Sheeba 4176489 YP_665027.1 CDS omp20 fragment 1 NC_008229.1 1100455 1100892 R hypothetical protein complement(1100455..1100892) Helicobacter acinonychis str. Sheeba 4176488 YP_665028.1 CDS Hac_1285 NC_008229.1 1101636 1102157 D hypothetical protein 1101636..1102157 Helicobacter acinonychis str. Sheeba 4176266 YP_665029.1 CDS hypD NC_008229.1 1102108 1103220 R (P31904) Hydrogenase expression/formation protein hypD2; High confidence in function and specificity; hydrogenase expression/formation protein complement(1102108..1103220) Helicobacter acinonychis str. Sheeba 4177671 YP_665030.1 CDS hypC NC_008229.1 1103226 1103462 R (P31900) Hydrogenase expression/formation protein hypC; Function unclear; hydrogenase expression/formation protein complement(1103226..1103462) Helicobacter acinonychis str. Sheeba 4177670 YP_665031.1 CDS hypB NC_008229.1 1103462 1104190 R (Q9ZKU8) Hydrogenase/urease nickel incorporation protein hypB; High confidence in function and specificity; hydrogenase expression/formation protein complement(1103462..1104190) Helicobacter acinonychis str. Sheeba 4177552 YP_665032.1 CDS ackA NC_008229.1 1104466 1105668 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(1104466..1105668) Helicobacter acinonychis str. Sheeba 4177694 YP_665033.1 CDS pta NC_008229.1 1105678 1107201 R (Q9ZKU4) Phosphate acetyltransferase (EC 2.3.1.8) (Phosphotransacetylase); High confidence in function and specificity; phosphate acetyltransferase complement(1105678..1107201) Helicobacter acinonychis str. Sheeba 4177739 YP_665034.1 CDS Hac_1293 NC_008229.1 1107578 1109137 D hypothetical protein 1107578..1109137 Helicobacter acinonychis str. Sheeba 4176267 YP_665035.1 CDS flgD NC_008229.1 1109188 1110066 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; flagellar basal body rod modification protein 1109188..1110066 Helicobacter acinonychis str. Sheeba 4177243 YP_665036.1 CDS flgE NC_008229.1 1110063 1111880 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1110063..1111880 Helicobacter acinonychis str. Sheeba 4177245 YP_665037.1 CDS Hac_1296 NC_008229.1 1111937 1112560 D restriction endonuclease 1111937..1112560 Helicobacter acinonychis str. Sheeba 4176268 YP_665038.1 CDS HINDIIM NC_008229.1 1112553 1113686 D (P43423) Modification methylase BseCI (EC 2.1.1.72) (Adenine-specific methyltransferase BseCI) (M.BseCI); High confidence in function and specificity; site specific DNA-methyltransferase 1112553..1113686 Helicobacter acinonychis str. Sheeba 4177432 YP_665039.1 CDS rep NC_008229.1 1113695 1115713 D High confidence in function and specificity; ATP-dependent DNA helicase 1113695..1115713 Helicobacter acinonychis str. Sheeba 4177073 YP_665040.1 CDS omp21 NC_008229.1 1116704 1118254 D outer membrane protein 21 1116704..1118254 Helicobacter acinonychis str. Sheeba 4176490 YP_665041.1 CDS omp22 NC_008229.1 1118276 1119772 D outer membrane protein 22 1118276..1119772 Helicobacter acinonychis str. Sheeba 4176570 YP_665042.1 CDS fecA NC_008229.1 1120003 1122528 R (P13036) Iron(III) dicitrate transport protein fecA precursor; High confidence in function and specificity; iron(III) dicitrate transport protein complement(1120003..1122528) Helicobacter acinonychis str. Sheeba 4176812 YP_665043.1 CDS omp23 NC_008229.1 1122691 1122930 D Outer membrane protein ,fecA inserted, fragment; hypothetical protein; outer membrane protein 23 1122691..1122930 Helicobacter acinonychis str. Sheeba 4176571 YP_665044.1 CDS yckJ NC_008229.1 1123021 1123716 R ABC-type Amino-acid transport system, permease component.; High confidence in function and specificity; amino acid ABC transporter permease complement(1123021..1123716) Helicobacter acinonychis str. Sheeba 4177711 YP_665045.1 CDS yckK NC_008229.1 1123718 1124491 R High confidence in function and specificity; polar amino acid ABC transporter periplasmic protein complement(1123718..1124491) Helicobacter acinonychis str. Sheeba 4177712 YP_665046.1 CDS Hac_1307 NC_008229.1 1124850 1125203 R Homologous to H. pylori gene product HP0947,jhp0881; hypothetical protein; hypothetical protein complement(1124850..1125203) Helicobacter acinonychis str. Sheeba 4176269 YP_665047.1 CDS Hac_1309 NC_008229.1 1125689 1127179 R Conserved hypothetical protein; hypothetical protein complement(1125689..1127179) Helicobacter acinonychis str. Sheeba 4176270 YP_665048.1 CDS Hac_1310 NC_008229.1 1128508 1128885 D Conserved hypothetical protein; Conserved hypothetical protein; hypothetical protein 1128508..1128885 Helicobacter acinonychis str. Sheeba 4176271 YP_665049.1 CDS dadA NC_008229.1 1128908 1130140 D High confidence in function and specificity; D-amino acid dehydrogenase subunit 1128908..1130140 Helicobacter acinonychis str. Sheeba 4176399 YP_665050.1 CDS dagA NC_008229.1 1130184 1131536 D sodium/ alanine symporter; High confidence in function and specificity; amino acid transporter 1130184..1131536 Helicobacter acinonychis str. Sheeba 4176400 YP_665051.1 CDS Hac_1313 NC_008229.1 1131544 1132677 D (Q9ZKQ9) Alanine racemase (EC 5.1.1.1); High confidence in function and specificity; hypothetical protein 1131544..1132677 Helicobacter acinonychis str. Sheeba 4176272 YP_665052.1 CDS rplS NC_008229.1 1133190 1133546 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(1133190..1133546) Helicobacter acinonychis str. Sheeba 4176850 YP_665053.1 CDS trmD NC_008229.1 1133568 1134242 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1133568..1134242) Helicobacter acinonychis str. Sheeba 4177489 YP_665054.1 CDS rimM NC_008229.1 1134258 1134800 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(1134258..1134800) Helicobacter acinonychis str. Sheeba 4177091 YP_665055.1 CDS Hac_1317 NC_008229.1 1134808 1135161 R Conserved hypothetical protein; hypothetical protein complement(1134808..1135161) Helicobacter acinonychis str. Sheeba 4176273 YP_665056.1 CDS rpsP NC_008229.1 1135177 1135407 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1135177..1135407) Helicobacter acinonychis str. Sheeba 4177155 YP_665057.1 CDS ffh NC_008229.1 1135479 1136825 R (Q9ZK62) Signal recognition particle protein (Fifty-four homolog); High confidence in function and specificity; signal recognition particle protein complement(1135479..1136825) Helicobacter acinonychis str. Sheeba 4176818 YP_665058.1 CDS valS NC_008229.1 1136841 1139459 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(1136841..1139459) Helicobacter acinonychis str. Sheeba 4176630 YP_665059.1 CDS Hac_1321 NC_008229.1 1139584 1139991 D binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly protein FliW 1139584..1139991 Helicobacter acinonychis str. Sheeba 4176274 YP_665060.1 CDS murG NC_008229.1 1140001 1141062 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1140001..1141062 Helicobacter acinonychis str. Sheeba 4177656 YP_665061.1 CDS omp24 NC_008229.1 1141172 1143211 D Conserved hypothetical protein; outer membrane protein 24 1141172..1143211 Helicobacter acinonychis str. Sheeba 4176572 YP_665062.1 CDS omp25 NC_008229.1 1143233 1146958 D Conserved hypothetical protein; outer membrane protein 25 1143233..1146958 Helicobacter acinonychis str. Sheeba 4176573 YP_665063.1 CDS proC NC_008229.1 1146972 1147745 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1146972..1147745 Helicobacter acinonychis str. Sheeba 4176563 YP_665064.1 CDS fic NC_008229.1 1147776 1148309 D High confidence in function and specificity; cell filamentation protein Fic 1147776..1148309 Helicobacter acinonychis str. Sheeba 4176819 YP_665065.1 CDS Hac_1327 NC_008229.1 1148394 1148816 R Conserved hypothetical protein; metalloprotease complement(1148394..1148816) Helicobacter acinonychis str. Sheeba 4176275 YP_665066.1 CDS fldA NC_008229.1 1148883 1149377 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(1148883..1149377) Helicobacter acinonychis str. Sheeba 4177239 YP_665067.1 CDS Hac_1329 NC_008229.1 1149480 1150061 R Conserved hypothetical integral membrane protein; Function unclear; hypothetical protein complement(1149480..1150061) Helicobacter acinonychis str. Sheeba 4176276 YP_665068.1 CDS Hac_1330 NC_008229.1 1150195 1150392 D Probable Nitrogen fixation protein fixS; Function unclear; hypothetical protein 1150195..1150392 Helicobacter acinonychis str. Sheeba 4176791 YP_665069.1 CDS trxB NC_008229.1 1150403 1151374 D (P52214) Thioredoxin reductase (EC 1.8.1.9) (TRXR) (TR); High confidence in function and specificity; thioredoxin reductase 1150403..1151374 Helicobacter acinonychis str. Sheeba 4176674 YP_665070.1 CDS permease fragment 4 NC_008229.1 1151626 1151862 R permease of Major facilitator Superfamily.; hypothetical protein; hypothetical protein complement(1151626..1151862) Helicobacter acinonychis str. Sheeba 4176749 YP_665071.1 CDS permease fragment 3 NC_008229.1 1151831 1152154 R Function unclear; hypothetical protein complement(1151831..1152154) Helicobacter acinonychis str. Sheeba 4176748 YP_665072.1 CDS Hac prophage I orf1 NC_008229.1 1152699 1153268 D Function unclear; integrase 1152699..1153268 Helicobacter acinonychis str. Sheeba 4177573 YP_665073.1 CDS Hac prophage I orf2 NC_008229.1 1153745 1155343 R Function unclear; helicase complement(1153745..1155343) Helicobacter acinonychis str. Sheeba 4177574 YP_665074.1 CDS Hac prophage I orf3 NC_008229.1 1155450 1158692 R Conserved hypothetical protein; helicase complement(1155450..1158692) Helicobacter acinonychis str. Sheeba 4177575 YP_665075.1 CDS Hac prophage I orf4 NC_008229.1 1159373 1159579 R Probable tautomerase; Conserved hypothetical protein; tautomerase complement(1159373..1159579) Helicobacter acinonychis str. Sheeba 4177576 YP_665076.1 CDS Hac prophage I orf5 NC_008229.1 1159916 1160125 R DNA repair and recombination protein.; Conserved hypothetical protein; hypothetical protein complement(1159916..1160125) Helicobacter acinonychis str. Sheeba 4177577 YP_665077.1 CDS Hac prophage I orf6 NC_008229.1 1160336 1160602 R hypothetical protein complement(1160336..1160602) Helicobacter acinonychis str. Sheeba 4177578 YP_665078.1 CDS Hac prophage I orf7 NC_008229.1 1161236 1161766 R Specificity unclear; hypothetical protein complement(1161236..1161766) Helicobacter acinonychis str. Sheeba 4177579 YP_665079.1 CDS Hac prophage I orf8 NC_008229.1 1163269 1163655 R hypothetical protein complement(1163269..1163655) Helicobacter acinonychis str. Sheeba 4177580 YP_665080.1 CDS Hac prophage I orf9 NC_008229.1 1163911 1164390 R hypothetical protein complement(1163911..1164390) Helicobacter acinonychis str. Sheeba 4177581 YP_665081.1 CDS permease fragment 2 NC_008229.1 1164696 1165070 R Function unclear; hypothetical protein complement(1164696..1165070) Helicobacter acinonychis str. Sheeba 4176747 YP_665082.1 CDS permease fragment 1 NC_008229.1 1165197 1165355 R Function unclear; hypothetical protein complement(1165197..1165355) Helicobacter acinonychis str. Sheeba 4176746 YP_665083.1 CDS pgi NC_008229.1 1165417 1167054 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1165417..1167054 Helicobacter acinonychis str. Sheeba 4176772 YP_665084.1 CDS Hac_1347 NC_008229.1 1167071 1167685 D hypothetical protein 1167071..1167685 Helicobacter acinonychis str. Sheeba 4176792 YP_665085.1 CDS Hac_1348 NC_008229.1 1167696 1168841 D (P12364) Type III restriction-modification system EcoP15I enzyme mod (EC 2.1.1.72) (EcoP15I methyltransferase) (M.EcoP15I); High confidence in function and specificity; type II restriction-modification methyltransferase 1167696..1168841 Helicobacter acinonychis str. Sheeba 4176793 YP_665086.1 CDS xseA NC_008229.1 1168879 1170141 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit complement(1168879..1170141) Helicobacter acinonychis str. Sheeba 4176641 YP_665087.1 CDS Hac_1350 NC_008229.1 1170154 1171197 R Specificity unclear; zinc metalloprotease complement(1170154..1171197) Helicobacter acinonychis str. Sheeba 4176794 YP_665088.1 CDS Hac_1351 NC_008229.1 1171197 1171877 R High confidence in function and specificity; hypothetical protein complement(1171197..1171877) Helicobacter acinonychis str. Sheeba 4176795 YP_665089.1 CDS Hac_1352 NC_008229.1 1171870 1172298 R hypothetical protein complement(1171870..1172298) Helicobacter acinonychis str. Sheeba 4176796 YP_665090.1 CDS purA NC_008229.1 1172295 1173530 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(1172295..1173530) Helicobacter acinonychis str. Sheeba 4177742 YP_665091.1 CDS omp26 NC_008229.1 1173606 1175021 R outer membrane protein 26 complement(1173606..1175021) Helicobacter acinonychis str. Sheeba 4176574 YP_665092.1 CDS omp27 NC_008229.1 1175034 1176449 R outer membrane protein 27 complement(1175034..1176449) Helicobacter acinonychis str. Sheeba 4176575 YP_665093.1 CDS oppC fragment 1 NC_008229.1 1176856 1176996 D peptide ABC transporter permease oppC fragment 1 1176856..1176996 Helicobacter acinonychis str. Sheeba 4177323 YP_665094.1 CDS oppC fragment 2 NC_008229.1 1177009 1177254 D ABC transporter permease; High confidence in function and specificity; peptide ABC transporter permease oppC fragment 2 1177009..1177254 Helicobacter acinonychis str. Sheeba 4177324 YP_665095.1 CDS oppC fragment 3 NC_008229.1 1177278 1177466 D ABC-type peptide transport, permease component; Function unclear; peptide ABC transporter permease oppC fragment 3 1177278..1177466 Helicobacter acinonychis str. Sheeba 4177325 YP_665096.1 CDS oppC fragment 4 NC_008229.1 1177430 1177657 D ABC transporter permease; Function unclear; peptide ABC transporter permease oppC fragment 3 1177430..1177657 Helicobacter acinonychis str. Sheeba 4177326 YP_665097.1 CDS oppC fragment 5 NC_008229.1 1177657 1177818 D ABC-type peptide transport, permease component; Function unclear; peptide ABC transporter permease oppC fragment 5 1177657..1177818 Helicobacter acinonychis str. Sheeba 4177327 YP_665098.1 CDS oppD fragment 1 NC_008229.1 1177833 1178177 D Peptide transport ATP-binding protein; High confidence in function and specificity; peptide ABC transporter ATP-binding protein oppD fragment 1 1177833..1178177 Helicobacter acinonychis str. Sheeba 4177328 YP_665099.1 CDS oppD fragment 2 NC_008229.1 1178120 1178416 D Probable ABC-type transport system, ATPase component.; hypothetical protein; peptide ABC transporter ATP-binding protein oppD fragment 2 1178120..1178416 Helicobacter acinonychis str. Sheeba 4177329 YP_665100.1 CDS oppD fragment 3 NC_008229.1 1178519 1178839 D (P33916) Hypothetical ABC transporter ATP-binding protein yejF; hypothetical protein; peptide ABC transporter ATP-binding protein oppD fragment 3 1178519..1178839 Helicobacter acinonychis str. Sheeba 4177330 YP_665101.1 CDS oppD fragment 4 NC_008229.1 1178840 1179199 D (P24137) Oligopeptide transport ATP-binding protein oppF; High confidence in function and specificity; peptide ABC transporter ATP-binding protein oppD fragment 4 1178840..1179199 Helicobacter acinonychis str. Sheeba 4177331 YP_665102.1 CDS Hac_1368 NC_008229.1 1179348 1179887 R hypothetical protein complement(1179348..1179887) Helicobacter acinonychis str. Sheeba 4176797 YP_665103.1 CDS Hac_1369 NC_008229.1 1179894 1180988 R Function unclear; hypothetical protein complement(1179894..1180988) Helicobacter acinonychis str. Sheeba 4176798 YP_665104.1 CDS deaD NC_008229.1 1181007 1182491 R High confidence in function and specificity; ATP-dependent RNA helicase complement(1181007..1182491) Helicobacter acinonychis str. Sheeba 4177123 YP_665105.1 CDS flgI NC_008229.1 1182666 1183691 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1182666..1183691 Helicobacter acinonychis str. Sheeba 4177249 YP_665106.1 CDS Hac_1372 NC_008229.1 1183688 1184005 D Specificity unclear; hypothetical protein 1183688..1184005 Helicobacter acinonychis str. Sheeba 4176799 YP_665107.1 CDS atoS NC_008229.1 1184002 1185129 D High confidence in function and specificity; hypothetical protein 1184002..1185129 Helicobacter acinonychis str. Sheeba 4177101 YP_665108.1 CDS napA NC_008229.1 1185522 1185956 D High confidence in function and specificity; neutrophil-activating protein A 1185522..1185956 Helicobacter acinonychis str. Sheeba 4177667 YP_665109.1 CDS Hac_1376 NC_008229.1 1185974 1186258 D (Q55790) Hypothetical protein slr0074; hypothetical protein; hypothetical protein 1185974..1186258 Helicobacter acinonychis str. Sheeba 4176800 YP_665110.1 CDS Hac_1377 NC_008229.1 1186275 1186646 D hypothetical protein 1186275..1186646 Helicobacter acinonychis str. Sheeba 4176801 YP_665111.1 CDS ispB NC_008229.1 1186656 1187579 D Bifunctional short chain isoprenyl diphosphate synthase [Includes: Farnesyl pyrophosphate synthetase (EC 2.5.1.1) (FPP synthetase) (Dimethylallyltransferase); Geranyltranstransferase (EC 2.5.1.10)]; High confidence in function and specificity; octaprenyl-diphosphate synthase 1186656..1187579 Helicobacter acinonychis str. Sheeba 4176129 YP_665112.1 CDS hemA NC_008229.1 1187579 1188922 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1187579..1188922 Helicobacter acinonychis str. Sheeba 4177421 YP_665113.1 CDS proS NC_008229.1 1188926 1190659 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1188926..1190659 Helicobacter acinonychis str. Sheeba 4176564 YP_665114.1 CDS hemC NC_008229.1 1190670 1191590 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 1190670..1191590 Helicobacter acinonychis str. Sheeba 4177423 YP_665115.1 CDS Hac_1382 NC_008229.1 1191590 1191955 D hypothetical protein 1191590..1191955 Helicobacter acinonychis str. Sheeba 4176802 YP_665116.1 CDS Hac_1383 NC_008229.1 1192063 1193124 D Specificity unclear; hypothetical protein 1192063..1193124 Helicobacter acinonychis str. Sheeba 4176803 YP_665117.1 CDS Hac_1385 NC_008229.1 1193240 1193437 D hypothetical protein 1193240..1193437 Helicobacter acinonychis str. Sheeba 4176804 YP_665118.1 CDS omp28 fragment 1 NC_008229.1 1193541 1194152 D hypothetical protein 1193541..1194152 Helicobacter acinonychis str. Sheeba 4176576 YP_665119.1 CDS omp28 fragment 2 NC_008229.1 1194225 1194584 D hypothetical protein 1194225..1194584 Helicobacter acinonychis str. Sheeba 4176577 YP_665120.1 CDS omp28 fragment 3 NC_008229.1 1194569 1194961 D hypothetical protein 1194569..1194961 Helicobacter acinonychis str. Sheeba 4176578 YP_665121.1 CDS omp28 fragment 4 NC_008229.1 1195040 1195294 D hypothetical protein 1195040..1195294 Helicobacter acinonychis str. Sheeba 4176579 YP_665122.1 CDS Hac_1390 NC_008229.1 1195464 1195688 D hypothetical protein 1195464..1195688 Helicobacter acinonychis str. Sheeba 4176805 YP_665123.1 CDS Hac_1391 NC_008229.1 1196228 1196587 D ABC-type cobalt transport system, ATP-binding protein; Function unclear; multidrug ABC transporter, ATPase component 1196228..1196587 Helicobacter acinonychis str. Sheeba 4176806 YP_665124.1 CDS Hac_1392 NC_008229.1 1196587 1197195 D Conserved hypothetical protein; multidrug ABC transporter permease 1196587..1197195 Helicobacter acinonychis str. Sheeba 4176807 YP_665125.1 CDS vacA paralog NC_008229.1 1197386 1207036 R vacuolating cytotoxin precursor; Specificity unclear; vacuolating cytotoxin VacA complement(1197386..1207036) Helicobacter acinonychis str. Sheeba 4176628 YP_665126.1 CDS Hac_1394 NC_008229.1 1207198 1207767 R hypothetical protein complement(1207198..1207767) Helicobacter acinonychis str. Sheeba 4176808 YP_665127.1 CDS acrB NC_008229.1 1207764 1210850 R AcrB/AcrD/AcrF family protein; High confidence in function and specificity; cation/multidrug efflux pump protein complement(1207764..1210850) Helicobacter acinonychis str. Sheeba 4177698 YP_665128.1 CDS Hac_1396 NC_008229.1 1210863 1211567 R Probable membrane-fusion protein; Function unclear; hypothetical protein complement(1210863..1211567) Helicobacter acinonychis str. Sheeba 4176809 YP_665129.1 CDS tolC NC_008229.1 1211581 1213014 R Outer membrane protein precursor; Function unclear; hypothetical protein complement(1211581..1213014) Helicobacter acinonychis str. Sheeba 4177486 YP_665130.1 CDS hemE NC_008229.1 1213027 1214046 R catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase complement(1213027..1214046) Helicobacter acinonychis str. Sheeba 4177425 YP_665131.1 CDS Hac_1400 NC_008229.1 1214172 1214729 R hypothetical protein complement(1214172..1214729) Helicobacter acinonychis str. Sheeba 4177299 YP_665132.1 CDS Hac_1401 NC_008229.1 1214726 1215382 R High confidence in function and specificity; 3-methyladenine DNA glycosylase complement(1214726..1215382) Helicobacter acinonychis str. Sheeba 4177300 YP_665133.1 CDS flaA NC_008229.1 1215794 1217326 R FlaA; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin A complement(1215794..1217326) Helicobacter acinonychis str. Sheeba 4176824 YP_665134.1 CDS fragment 1 NC_008229.1 1217701 1217961 D Function unclear; secretion/efflux ABC transporter ATP-binding protein fragment 1 1217701..1217961 Helicobacter acinonychis str. Sheeba 4177053 YP_665135.1 CDS fragment 2 NC_008229.1 1218208 1218309 D secretion/efflux ABC transporter ATP-binding protein fragment 2 1218208..1218309 Helicobacter acinonychis str. Sheeba 4177033 YP_665136.1 CDS fragment 3 NC_008229.1 1218400 1218891 D Multidrug resistance ABC transporter ATP-binding and permease; Function unclear; secretion/efflux ABC transporter ATP-binding protein fragment 3 1218400..1218891 Helicobacter acinonychis str. Sheeba 4177292 YP_665137.1 CDS fragment 4 NC_008229.1 1218961 1219104 D Function unclear; secretion/efflux ABC transporter ATP-binding protein fragment 4 1218961..1219104 Helicobacter acinonychis str. Sheeba 4176514 YP_665138.1 CDS mcp NC_008229.1 1219168 1220469 D High confidence in function and specificity; methyl-accepting chemotaxis protein (MCP) 1219168..1220469 Helicobacter acinonychis str. Sheeba 4176757 YP_665139.1 CDS bioF NC_008229.1 1220483 1221604 D High confidence in function and specificity; 8-amino-7-oxononanoate synthase 1220483..1221604 Helicobacter acinonychis str. Sheeba 4177118 YP_665140.1 CDS pbp NC_008229.1 1221605 1223584 D Penicillin-binding protein 1A (PBP-1a) (PBP1a) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.2.-) (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC 3.4.-.-) (DD-transpeptidase)]; High confidence in function and specificity; penicillin-binding protein 1221605..1223584 Helicobacter acinonychis str. Sheeba 4176738 YP_665141.2 CDS Hac_1412 NC_008229.1 1223587 1224165 R Tip-alpha; forms a dimer; found in culture supernatant; induces TNF-alpha and NF-kappa-B in cell cultures of mouse cells; tumor necrosis factor alpha-inducing protein complement(1223587..1224165) Helicobacter acinonychis str. Sheeba 4177301 YP_665142.1 CDS Hac_1413 NC_008229.1 1224325 1224528 D hypothetical protein 1224325..1224528 Helicobacter acinonychis str. Sheeba 4177302 YP_665143.1 CDS Hac_1414 NC_008229.1 1224640 1226112 R hypothetical protein complement(1224640..1226112) Helicobacter acinonychis str. Sheeba 4177303 YP_665144.1 CDS Hac_1415 NC_008229.1 1226121 1226285 R hypothetical protein complement(1226121..1226285) Helicobacter acinonychis str. Sheeba 4177304 YP_665145.1 CDS mod NC_008229.1 1226392 1228236 R Type III restriction-modification system EcoPI enzyme mod (EC 2.1.1.72) (EcoPI methyltransferase) (M.EcoPI); High confidence in function and specificity; adenine specific DNA methylase complement(1226392..1228236) Helicobacter acinonychis str. Sheeba 4176771 YP_665146.1 CDS res NC_008229.1 1228253 1231192 R High confidence in function and specificity; type III restriction enzyme R protein complement(1228253..1231192) Helicobacter acinonychis str. Sheeba 4177076 YP_665147.1 CDS oorC NC_008229.1 1231341 1231901 R 2-oxoglutarate synthase subunit korC (EC 1.2.7.3) (2-ketoglutarate oxidoreductase gamma chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase gamma subunit); High confidence in function and specificity; 2-oxoglutarate-acceptor oxidoreductase subunit OorC complement(1231341..1231901) Helicobacter acinonychis str. Sheeba 4176445 YP_665148.1 CDS oorB NC_008229.1 1231901 1232722 R 2-oxoglutarate synthase subunit korB (EC 1.2.7.3) (2-ketoglutarate oxidoreductase beta chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase beta subunit); High confidence in function and specificity; 2-oxoglutarate-acceptor oxidoreductase subunit OorB complement(1231901..1232722) Helicobacter acinonychis str. Sheeba 4176444 YP_665149.1 CDS oorA NC_008229.1 1232724 1233851 R 2-oxoglutarate synthase subunit korA (EC 1.2.7.3) (2-ketoglutarate oxidoreductase alpha chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase alpha subunit); High confidence in function and specificity; 2-oxoglutarate-acceptor oxidoreductase subunit OorA complement(1232724..1233851) Helicobacter acinonychis str. Sheeba 4176443 YP_665150.1 CDS oorD NC_008229.1 1233851 1234192 R NADH-ubiquinone oxidoreductase 23 kDa subunit mitochondrial precursor (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-23KD) (CI-23KD) (Complex I-28.5KD) (CI-28.5KD); High confidence in function and specificity; 2-oxoglutarate-acceptor oxidoreductase subunit OorD complement(1233851..1234192) Helicobacter acinonychis str. Sheeba 4176446 YP_665151.1 CDS pabC NC_008229.1 1234372 1235367 R High confidence in function and specificity; aminodeoxychorismate lyase complement(1234372..1235367) Helicobacter acinonychis str. Sheeba 4177334 YP_665152.1 CDS Hac_1425 NC_008229.1 1235285 1238221 D hypothetical protein 1235285..1238221 Helicobacter acinonychis str. Sheeba 4177305 YP_665153.1 CDS feoA NC_008229.1 1238218 1238448 D Ferrous iron transport protein A; High confidence in function and specificity; ferrous iron transport protein A 1238218..1238448 Helicobacter acinonychis str. Sheeba 4176816 YP_665154.1 CDS nth NC_008229.1 1238450 1239100 D Endonuclease III (EC 4.2.99.18) (DNA-(apurinic or apyrimidinic site) lyase); High confidence in function and specificity; endonuclease III 1238450..1239100 Helicobacter acinonychis str. Sheeba 4177450 YP_665155.1 CDS fliN NC_008229.1 1239178 1239549 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein 1239178..1239549 Helicobacter acinonychis str. Sheeba 4177502 YP_665156.1 CDS Hac_1429 NC_008229.1 1239546 1240436 D hypothetical protein 1239546..1240436 Helicobacter acinonychis str. Sheeba 4177306 YP_665157.1 CDS Hac_1430 NC_008229.1 1240450 1241331 D SIDEROPHORE-MEDIATED IRON TRANSPORT PROTEIN; Function unclear; hypothetical protein 1240450..1241331 Helicobacter acinonychis str. Sheeba 4177307 YP_665158.1 CDS pyrC NC_008229.1 1241341 1242360 D catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1241341..1242360 Helicobacter acinonychis str. Sheeba 4177751 YP_665159.1 CDS Hac_1432 NC_008229.1 1242411 1243454 D Predicted neuraminidase (sialidase); Function unclear; neuraminidase (sialidase) 1242411..1243454 Helicobacter acinonychis str. Sheeba 4177308 YP_665160.1 CDS Hac_1433 NC_008229.1 1243460 1244011 D hypothetical protein 1243460..1244011 Helicobacter acinonychis str. Sheeba 4177309 YP_665161.1 CDS Hac_1434 NC_008229.1 1244017 1246047 D Probable phosphoglycerol transferase; Specificity unclear; hypothetical protein 1244017..1246047 Helicobacter acinonychis str. Sheeba 4177310 YP_665162.1 CDS folD NC_008229.1 1246301 1247179 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1246301..1247179 Helicobacter acinonychis str. Sheeba 4177510 YP_665163.1 CDS lepB NC_008229.1 1247180 1248052 D Signal peptidase I (EC 3.4.21.89) (SPase I) (Leader peptidase I); High confidence in function and specificity; hypothetical protein 1247180..1248052 Helicobacter acinonychis str. Sheeba 4177612 YP_665164.1 CDS Hac_1437 NC_008229.1 1248061 1248759 D (O67776) Hypothetical zinc metalloprotease AQ_1964 (EC 3.4.24.-); Function unclear; hypothetical protein 1248061..1248759 Helicobacter acinonychis str. Sheeba 4177311 YP_665165.1 CDS rpiB NC_008229.1 1248780 1249241 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 1248780..1249241 Helicobacter acinonychis str. Sheeba 4176832 YP_665166.1 CDS Hac_1439 NC_008229.1 1249287 1249619 D hypothetical protein 1249287..1249619 Helicobacter acinonychis str. Sheeba 4177312 YP_665167.1 CDS apt NC_008229.1 1249654 1250193 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1249654..1250193 Helicobacter acinonychis str. Sheeba 4176930 YP_665168.1 CDS Hac_1441 NC_008229.1 1250205 1250783 D Specificity unclear; hypothetical protein 1250205..1250783 Helicobacter acinonychis str. Sheeba 4177313 YP_665169.1 CDS pepA NC_008229.1 1250833 1252323 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 1250833..1252323 Helicobacter acinonychis str. Sheeba 4176744 YP_665170.1 CDS Hac_1443 NC_008229.1 1252325 1253425 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1252325..1253425 Helicobacter acinonychis str. Sheeba 4177314 YP_665171.1 CDS Hac_1444 NC_008229.1 1253463 1253615 D hypothetical protein 1253463..1253615 Helicobacter acinonychis str. Sheeba 4177315 YP_665172.1 CDS fragment 1 NC_008229.1 1253594 1253851 D hypothetical protein 1253594..1253851 Helicobacter acinonychis str. Sheeba 4177054 YP_665173.1 CDS fragment 2 NC_008229.1 1253887 1254333 D hypothetical protein 1253887..1254333 Helicobacter acinonychis str. Sheeba 4177034 YP_665174.1 CDS fecA NC_008229.1 1254473 1256845 D (P13036) Iron(III) dicitrate transport protein fecA precursor; High confidence in function and specificity; iron(III) dicitrate transport protein 1254473..1256845 Helicobacter acinonychis str. Sheeba 4176813 YP_665175.1 CDS Hac_1450 NC_008229.1 1257548 1258468 R hypothetical protein complement(1257548..1258468) Helicobacter acinonychis str. Sheeba 4177316 YP_665176.1 CDS Hac_1451 NC_008229.1 1258704 1259138 R hypothetical protein complement(1258704..1259138) Helicobacter acinonychis str. Sheeba 4177317 YP_665177.1 CDS omp29 NC_008229.1 1259480 1260340 R outer membrane protein 29 complement(1259480..1260340) Helicobacter acinonychis str. Sheeba 4176580 YP_665178.1 CDS rplT NC_008229.1 1260523 1260873 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1260523..1260873) Helicobacter acinonychis str. Sheeba 4176833 YP_665179.1 CDS infC NC_008229.1 1261140 1261751 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(1261140..1261751) Helicobacter acinonychis str. Sheeba 4177682 YP_665180.1 CDS thrS NC_008229.1 1261748 1263586 R catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase complement(1261748..1263586) Helicobacter acinonychis str. Sheeba 4177477 YP_665181.1 CDS Hac_1458 NC_008229.1 1263631 1263771 R (O24940) Hypothetical protein HP0122/JHP0112 precursor; Conserved hypothetical protein; hypothetical protein complement(1263631..1263771) Helicobacter acinonychis str. Sheeba 4177318 YP_665182.1 CDS ppsA NC_008229.1 1263948 1266368 D catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 1263948..1266368 Helicobacter acinonychis str. Sheeba 4176556 YP_665183.1 CDS Hac_1460 NC_008229.1 1266560 1267270 D outer membrane protein; hypothetical protein; hypothetical protein 1266560..1267270 Helicobacter acinonychis str. Sheeba 4176946 YP_665184.1 CDS wbyL NC_008229.1 1267242 1268012 R Function unclear; glycosyl transferase family protein complement(1267242..1268012) Helicobacter acinonychis str. Sheeba 4176639 YP_665185.1 CDS tlpB NC_008229.1 1268043 1269740 R High confidence in function and specificity; hypothetical protein complement(1268043..1269740) Helicobacter acinonychis str. Sheeba 4177482 YP_665186.1 CDS luxS NC_008229.1 1270023 1270496 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(1270023..1270496) Helicobacter acinonychis str. Sheeba 4177626 YP_665187.1 CDS metB NC_008229.1 1270532 1271674 R catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine; cystathionine gamma-synthase complement(1270532..1271674) Helicobacter acinonychis str. Sheeba 4176761 YP_665188.1 CDS cysK NC_008229.1 1271700 1272614 R (Q9ZMW6) Cysteine synthase; High confidence in function and specificity; hypothetical protein complement(1271700..1272614) Helicobacter acinonychis str. Sheeba 4176396 YP_665189.1 CDS Hac_1466 NC_008229.1 1272692 1272856 D hypothetical protein 1272692..1272856 Helicobacter acinonychis str. Sheeba 4176947 YP_665190.1 CDS Hac_1467 NC_008229.1 1272881 1273165 R Probable proton transporting ATP synthase subunit,atp I; hypothetical protein; hypothetical protein complement(1272881..1273165) Helicobacter acinonychis str. Sheeba 4176948 YP_665191.1 CDS dnaK NC_008229.1 1273411 1275273 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(1273411..1275273) Helicobacter acinonychis str. Sheeba 4177135 YP_665192.1 CDS grpE NC_008229.1 1275301 1275861 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(1275301..1275861) Helicobacter acinonychis str. Sheeba 4177274 YP_665193.1 CDS hrcA NC_008229.1 1275858 1276661 R Acts as a negative regulator of the grpE-dnaK-dnaJ and groELS class I heat shock operons by preventing heat-shock induction; heat-inducible transcription repressor complement(1275858..1276661) Helicobacter acinonychis str. Sheeba 4176885 YP_665194.1 CDS Hac_1471 NC_008229.1 1276901 1277539 D ribulose-5-phosphate 4-epimerase; Function unclear; hypothetical protein 1276901..1277539 Helicobacter acinonychis str. Sheeba 4176949 YP_665195.1 CDS Hac_1472 NC_008229.1 1277560 1277862 D hypothetical protein 1277560..1277862 Helicobacter acinonychis str. Sheeba 4176950 YP_665196.1 CDS Hac_1473 NC_008229.1 1277872 1279755 R Function unclear; hypothetical protein complement(1277872..1279755) Helicobacter acinonychis str. Sheeba 4176951 YP_665197.1 CDS flaB NC_008229.1 1279803 1281347 R FlaB; structural flagella protein; in Helicobacter flagella are composed of flagellin A and flagellin B; the amounts of each seem to be controlled by environmental conditions; flagellin B complement(1279803..1281347) Helicobacter acinonychis str. Sheeba 4176826 YP_665198.1 CDS topA NC_008229.1 1281528 1283738 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1281528..1283738 Helicobacter acinonychis str. Sheeba 4177488 YP_665199.1 CDS Hac_1476 NC_008229.1 1283746 1284657 D Probable Fe-S oxidoreductases; Specificity unclear; hypothetical protein 1283746..1284657 Helicobacter acinonychis str. Sheeba 4176952 YP_665200.1 CDS Hac_1477 NC_008229.1 1284980 1286086 R Function unclear; hypothetical protein complement(1284980..1286086) Helicobacter acinonychis str. Sheeba 4176953 YP_665201.1 CDS mcp NC_008229.1 1286086 1288113 R Methyl-accepting chemotaxis protein; Function unclear; hypothetical protein complement(1286086..1288113) Helicobacter acinonychis str. Sheeba 4176758 YP_665202.1 CDS thrC NC_008229.1 1288291 1289763 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1288291..1289763 Helicobacter acinonychis str. Sheeba 4177476 YP_665203.1 CDS Hac_1480 NC_008229.1 1289869 1290579 D hypothetical protein 1289869..1290579 Helicobacter acinonychis str. Sheeba 4176954 YP_665204.1 CDS Hac_1481 NC_008229.1 1290829 1291773 R Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase complement(1290829..1291773) Helicobacter acinonychis str. Sheeba 4176955 YP_665205.1 CDS Hac_1482 NC_008229.1 1291845 1292357 D hypothetical protein 1291845..1292357 Helicobacter acinonychis str. Sheeba 4176956 YP_665206.1 CDS ISHa1152 tnpB fragment 3 NC_008229.1 1292680 1292778 R ISHp608-like IS element; hypothetical protein; ISHa1152 transposase B fragment 3 complement(1292680..1292778) Helicobacter acinonychis str. Sheeba 4176122 YP_665207.1 CDS ISHa1152 tnpB fragment 2 NC_008229.1 1292800 1292901 R ISHp608-like IS element; hypothetical protein; ISHa1152 transposase B fragment 2 complement(1292800..1292901) Helicobacter acinonychis str. Sheeba 4177689 YP_665208.1 CDS ISHa1152 tnpB fragment 1 NC_008229.1 1292882 1292995 R ISHp608-like IS element; hypothetical protein; ISHa1152 transposase B fragment 1 complement(1292882..1292995) Helicobacter acinonychis str. Sheeba 4177687 YP_665209.1 CDS ISHa1152 tnpA NC_008229.1 1292964 1293368 R N-terminal truncated, 1-22 aa missing,ISHp608-like IS element; Specificity unclear; ISHa1152 transposase A complement(1292964..1293368) Helicobacter acinonychis str. Sheeba 4177685 YP_665210.1 CDS Hac_1488 NC_008229.1 1293615 1293734 R hypothetical protein complement(1293615..1293734) Helicobacter acinonychis str. Sheeba 4176957 YP_665211.1 CDS omp30 fragment 1 NC_008229.1 1293739 1294389 D hypothetical protein 1293739..1294389 Helicobacter acinonychis str. Sheeba 4176582 YP_665212.1 CDS omp30 fragment 2 NC_008229.1 1294443 1294892 D hypothetical protein 1294443..1294892 Helicobacter acinonychis str. Sheeba 4176583 YP_665213.1 CDS omp30 fragment 3 NC_008229.1 1294940 1295704 D hypothetical protein 1294940..1295704 Helicobacter acinonychis str. Sheeba 4176584 YP_665214.1 CDS Hac_1493 NC_008229.1 1295815 1296648 R integral membrane protein; Specificity unclear; hypothetical protein complement(1295815..1296648) Helicobacter acinonychis str. Sheeba 4176958 YP_665215.1 CDS msrA NC_008229.1 1297098 1298132 R (Q9ZMK8) Peptide methionine sulfoxide reductase; High confidence in function and specificity; hypothetical protein complement(1297098..1298132) Helicobacter acinonychis str. Sheeba 4176731 YP_665216.1 CDS radA NC_008229.1 1298408 1299754 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(1298408..1299754) Helicobacter acinonychis str. Sheeba 4177064 YP_665217.1 CDS nifU NC_008229.1 1299767 1300747 R (P23121) Nitrogen fixation protein nifU; High confidence in function and specificity; nifU-like protein complement(1299767..1300747) Helicobacter acinonychis str. Sheeba 4177446 YP_665218.1 CDS nifS NC_008229.1 1300769 1301932 R (Q9ZML2) Cysteine desulfurase (EC 2.8.1.7); High confidence in function and specificity; hypothetical protein complement(1300769..1301932) Helicobacter acinonychis str. Sheeba 4177445 YP_665219.1 CDS Hac_1499 NC_008229.1 1302135 1302590 R hypothetical protein complement(1302135..1302590) Helicobacter acinonychis str. Sheeba 4176959 YP_665220.1 CDS Hac_1500 NC_008229.1 1302740 1303291 D Predicted phospholipid-binding protein; High confidence in function and specificity; hypothetical protein 1302740..1303291 Helicobacter acinonychis str. Sheeba 4176960 YP_665221.1 CDS Hac_1501 NC_008229.1 1303359 1304501 R glycosyltransferase; hypothetical protein; hypothetical protein complement(1303359..1304501) Helicobacter acinonychis str. Sheeba 4176961 YP_665222.1 CDS dxr fragment 2 NC_008229.1 1304578 1305318 R dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase [EC:1.1.1.267]; High confidence in function and specificity; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(1304578..1305318) Helicobacter acinonychis str. Sheeba 4176387 YP_665223.1 CDS dxr fragment 1 NC_008229.1 1305272 1305670 R dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase [EC:1.1.1.267]; High confidence in function and specificity; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(1305272..1305670) Helicobacter acinonychis str. Sheeba 4176386 YP_665224.1 CDS cdsA NC_008229.1 1305671 1306471 R High confidence in function and specificity; hypothetical protein complement(1305671..1306471) Helicobacter acinonychis str. Sheeba 4176596 YP_665225.1 CDS Hac_1505 NC_008229.1 1306480 1308141 R (Q8WWT9) Solute carrier family 13 member 3 (Sodium-dependent high-affinity dicarboxylate transporter 2); High confidence in function and specificity; sodium-dependent transporter complement(1306480..1308141) Helicobacter acinonychis str. Sheeba 4176962 YP_665226.1 CDS gidA NC_008229.1 1308237 1310102 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 1308237..1310102 Helicobacter acinonychis str. Sheeba 4177763 YP_665227.1 CDS dapE NC_008229.1 1310113 1311264 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 1310113..1311264 Helicobacter acinonychis str. Sheeba 4176404 YP_665228.1 CDS htpG NC_008229.1 1311605 1313470 R molecular chaperone; heat shock protein 90 complement(1311605..1313470) Helicobacter acinonychis str. Sheeba 4177543 YP_665229.1 CDS fucT fragment 1 NC_008229.1 1313638 1314102 D alpha-1,2-fucosyltransferase 1313638..1314102 Helicobacter acinonychis str. Sheeba 4177012 YP_665230.1 CDS fucT fragment 2 NC_008229.1 1314099 1314230 D alpha-1,2-fucosyltransferase 1314099..1314230 Helicobacter acinonychis str. Sheeba 4177014 YP_665231.1 CDS Hac_1512 NC_008229.1 1314237 1315073 R type II DNA modification enzyme (methyltransferase) [EC:2.1.1.72]; High confidence in function and specificity; DNA methyltransferase complement(1314237..1315073) Helicobacter acinonychis str. Sheeba 4176963 YP_665232.1 CDS hrgA fragment 2 NC_008229.1 1315091 1315783 R Conserved hypothetical protein; HrgA protein fragment 2 complement(1315091..1315783) Helicobacter acinonychis str. Sheeba 4176887 YP_665233.1 CDS hrgA fragment 1 NC_008229.1 1315752 1316093 R Function unclear; HrgA protein fragment 1 complement(1315752..1316093) Helicobacter acinonychis str. Sheeba 4176886 YP_665234.1 CDS fabD NC_008229.1 1316531 1317460 D (P71019) Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39) (MCT); High confidence in function and specificity; malonyl CoA-acyl carrier protein transacylase 1316531..1317460 Helicobacter acinonychis str. Sheeba 4177407 YP_665235.1 CDS Hac_1516 NC_008229.1 1317457 1318167 D enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1317457..1318167 Helicobacter acinonychis str. Sheeba 4176964 YP_665236.1 CDS rpoD NC_008229.1 1318546 1320525 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 1318546..1320525 Helicobacter acinonychis str. Sheeba 4176864 YP_665237.1 CDS Hac_1518 NC_008229.1 1320545 1321960 D exported protein; Conserved hypothetical protein; hypothetical protein 1320545..1321960 Helicobacter acinonychis str. Sheeba 4177338 YP_665238.1 CDS Hac_1519 NC_008229.1 1322013 1323365 D (O24913) Malate:quinone oxidoreductase (EC 1.1.99.16) (Malate dehydrogenase [acceptor]) (MQO); High confidence in function and specificity; malate dehydrogenase (acceptor) 1322013..1323365 Helicobacter acinonychis str. Sheeba 4177339 YP_665239.1 CDS Hac_1520 NC_008229.1 1323367 1323555 D (O24912) Hypothetical protein HP0085/JHP0078; Conserved hypothetical protein; hypothetical protein 1323367..1323555 Helicobacter acinonychis str. Sheeba 4177340 YP_665240.1 CDS rplM NC_008229.1 1323834 1324259 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1323834..1324259 Helicobacter acinonychis str. Sheeba 4176844 YP_665241.1 CDS rpsI NC_008229.1 1324256 1324645 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1324256..1324645 Helicobacter acinonychis str. Sheeba 4177149 YP_665242.1 CDS mcp NC_008229.1 1324790 1326811 D Methyl-accepting chemotaxis protein mcpB; Function unclear; hypothetical protein 1324790..1326811 Helicobacter acinonychis str. Sheeba 4176759 YP_665243.1 CDS Hac_1525 NC_008229.1 1327075 1328844 R hypothetical protein complement(1327075..1328844) Helicobacter acinonychis str. Sheeba 4177341 YP_665244.1 CDS prfA NC_008229.1 1328955 1330013 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(1328955..1330013) Helicobacter acinonychis str. Sheeba 4176559 YP_665245.1 CDS rpsT NC_008229.1 1330132 1330401 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(1330132..1330401) Helicobacter acinonychis str. Sheeba 4177159 YP_665246.1 CDS glmM NC_008229.1 1330492 1331829 D catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1330492..1331829 Helicobacter acinonychis str. Sheeba 4176729 YP_665247.1 CDS lspA NC_008229.1 1331823 1332296 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1331823..1332296 Helicobacter acinonychis str. Sheeba 4177625 YP_665248.1 CDS ureA NC_008229.1 1332632 1333348 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit alpha 1332632..1333348 Helicobacter acinonychis str. Sheeba 4176685 YP_665249.1 CDS ureB NC_008229.1 1333352 1335061 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureA(alpha) and 3 ureB (beta) subunits; urease subunit beta 1333352..1335061 Helicobacter acinonychis str. Sheeba 4176688 YP_665250.1 CDS ureI NC_008229.1 1335285 1335872 D High confidence in function and specificity; urease accessory protein 1335285..1335872 Helicobacter acinonychis str. Sheeba 4176693 YP_665251.1 CDS ureE NC_008229.1 1335874 1336386 D involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 1335874..1336386 Helicobacter acinonychis str. Sheeba 4176689 YP_665252.1 CDS ureF NC_008229.1 1336411 1337160 D (Q09065) Urease accessory protein ureF; High confidence in function and specificity; hypothetical protein 1336411..1337160 Helicobacter acinonychis str. Sheeba 4176690 YP_665253.1 CDS ureG NC_008229.1 1337191 1337790 D (Q9ZMZ7) Urease accessory protein ureG; High confidence in function and specificity; urease accessory protein UreG 1337191..1337790 Helicobacter acinonychis str. Sheeba 4176691 YP_665254.1 CDS ureH NC_008229.1 1337790 1338581 D (Q9ZMZ8) Urease accessory protein ureH; High confidence in function and specificity; urease accessory protein UreD 1337790..1338581 Helicobacter acinonychis str. Sheeba 4176692 YP_665255.1 CDS fragment 5 NC_008229.1 1338616 1338900 R hypothetical protein complement(1338616..1338900) Helicobacter acinonychis str. Sheeba 4176517 YP_665256.1 CDS fragment 4 NC_008229.1 1338804 1339100 R hypothetical protein complement(1338804..1339100) Helicobacter acinonychis str. Sheeba 4176515 YP_665257.1 CDS fragment 3 NC_008229.1 1339207 1339602 R Conserved hypothetical protein; hypothetical protein complement(1339207..1339602) Helicobacter acinonychis str. Sheeba 4177293 YP_665258.1 CDS fragment 2 NC_008229.1 1339718 1339924 R Function unclear; hypothetical protein complement(1339718..1339924) Helicobacter acinonychis str. Sheeba 4177035 YP_665259.1 CDS fragment 1 NC_008229.1 1340039 1340233 R hypothetical protein complement(1340039..1340233) Helicobacter acinonychis str. Sheeba 4177055 YP_665260.1 CDS rfaJ NC_008229.1 1340256 1341473 D (P27129) Lipopolysaccharide 1,2-glucosyltransferase; High confidence in function and specificity; lipopolysaccharide biosynthesis protein 1340256..1341473 Helicobacter acinonychis str. Sheeba 4177082 YP_665261.1 CDS Hac_1546 NC_008229.1 1341474 1341791 R Conserved hypothetical protein; hypothetical protein complement(1341474..1341791) Helicobacter acinonychis str. Sheeba 4177342 YP_665262.1 CDS fragment 3 NC_008229.1 1341775 1341906 R hypothetical protein complement(1341775..1341906) Helicobacter acinonychis str. Sheeba 4177294 YP_665263.1 CDS fragment 2 NC_008229.1 1341910 1342173 R hypothetical protein complement(1341910..1342173) Helicobacter acinonychis str. Sheeba 4177036 YP_665264.1 CDS fragment 1 NC_008229.1 1342163 1342288 R hypothetical protein complement(1342163..1342288) Helicobacter acinonychis str. Sheeba 4177056 YP_665265.1 CDS ISHa1675 tnpB NC_008229.1 1342387 1343670 R IS605 like IS element; High confidence in function and specificity; ISHa1675 transposase B complement(1342387..1343670) Helicobacter acinonychis str. Sheeba 4176124 YP_665266.1 CDS ISHa1675 tnpA NC_008229.1 1343828 1343941 D tnpA, N-terminal fragment; Function unclear; ISHa1675 transposase A N-terminal fragment 1343828..1343941 Helicobacter acinonychis str. Sheeba 4176123 YP_665267.1 CDS fragment 3 NC_008229.1 1344180 1344323 R hypothetical protein complement(1344180..1344323) Helicobacter acinonychis str. Sheeba 4177295 YP_665268.1 CDS fragment 2 NC_008229.1 1344357 1344563 R hypothetical protein complement(1344357..1344563) Helicobacter acinonychis str. Sheeba 4177037 YP_665269.1 CDS fragment 1 NC_008229.1 1344614 1344739 R hypothetical protein complement(1344614..1344739) Helicobacter acinonychis str. Sheeba 4177057 YP_665270.1 CDS Hac_1555 NC_008229.1 1344736 1344891 R hypothetical protein complement(1344736..1344891) Helicobacter acinonychis str. Sheeba 4177343 YP_665271.1 CDS Hac_1556 NC_008229.1 1345699 1345920 R hypothetical protein complement(1345699..1345920) Helicobacter acinonychis str. Sheeba 4177344 YP_665272.1 CDS putA NC_008229.1 1346235 1349792 D (O52485) Bifunctional putA protein [Includes: Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C dehydrogenase)](O52485) Bifunctional putA protein [Includes: Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C dehydrogenase)]; High confidence in function and specificity; proline/pyrroline dehydrogenase 1346235..1349792 Helicobacter acinonychis str. Sheeba 4177746 YP_665273.1 CDS putP NC_008229.1 1349819 1351315 D (P07117) Sodium/proline symporter (Proline permease); High confidence in function and specificity; sodium/proline symporter 1349819..1351315 Helicobacter acinonychis str. Sheeba 4177747 YP_665274.1 CDS rfaJ NC_008229.1 1351378 1352595 D (P25148) General stress protein A(P25148) General stress protein A; High confidence in function and specificity; lipopolysaccharide biosynthesis protein 1351378..1352595 Helicobacter acinonychis str. Sheeba 4177083 YP_665275.1 CDS mrp NC_008229.1 1352652 1353758 R (O24999) Mrp protein homolog(O24999) Mrp protein homolog; High confidence in function and specificity; mrp-like protein, ATP/GTP-binding protein complement(1352652..1353758) Helicobacter acinonychis str. Sheeba 4176728 YP_665276.1 CDS fragment 1 NC_008229.1 1353896 1356088 D hypothetical protein 1353896..1356088 Helicobacter acinonychis str. Sheeba 4177058 YP_665277.1 CDS fragment 2 NC_008229.1 1356101 1356991 D hypothetical protein 1356101..1356991 Helicobacter acinonychis str. Sheeba 4177038 YP_665278.1 CDS Hac_1564 NC_008229.1 1357031 1357414 D (P53127) Hypothetical 163.2 kDa protein in RPL1B-CEG1 intergenic region(P53127) Hypothetical 163.2 kDa protein in RPL1B-CEG1 intergenic region; conserved hypothetical protein; hypothetical protein 1357031..1357414 Helicobacter acinonychis str. Sheeba 4177345 YP_665279.1 CDS asd NC_008229.1 1357421 1358461 R (O25801) Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) (ASA dehydrogenase) (ASADH)(O25801) Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) (ASA dehydrogenase) (ASADH); High confidence in function and specificity; hypothetical protein complement(1357421..1358461) Helicobacter acinonychis str. Sheeba 4176939 YP_665280.1 CDS hisS NC_008229.1 1358448 1359776 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(1358448..1359776) Helicobacter acinonychis str. Sheeba 4177433 YP_665281.1 CDS rfaF NC_008229.1 1359838 1360887 D High confidence in function and specificity; ADP-heptose--LPS heptosyltransferase II 1359838..1360887 Helicobacter acinonychis str. Sheeba 4177079 YP_665282.1 CDS Hac_1568 NC_008229.1 1361033 1361359 R (P35612) Beta adducin (Erythrocyte adducin beta subunit)(P35612) Beta adducin (Erythrocyte adducin beta subunit); conserved hypothetical protein; hypothetical protein complement(1361033..1361359) Helicobacter acinonychis str. Sheeba 4177346 YP_665283.1 CDS tas1 fragment 1 NC_008229.1 1361600 1361971 D Function unclear; aldo-keto reductase 1361600..1361971 Helicobacter acinonychis str. Sheeba 4177468 YP_665284.1 CDS tas1 fragment 2 NC_008229.1 1362052 1362249 D (P49249) IN2-2 protein(P49249) IN2-2 protein; High confidence in function and specificity; aldo-keto reductase 1362052..1362249 Helicobacter acinonychis str. Sheeba 4177469 YP_665285.1 CDS tas1 fragment 3 NC_008229.1 1362246 1362563 D (Q09923) Aldo-keto reductase yakc [NADP+] (EC 1.1.1.-)(Q09923) Aldo-keto reductase yakc [NADP+] (EC 1.1.1.-); High confidence in function and specificity; aldo-keto reductase 1362246..1362563 Helicobacter acinonychis str. Sheeba 4177470 YP_665286.1 CDS fusA NC_008229.1 1363087 1365165 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(1363087..1365165) Helicobacter acinonychis str. Sheeba 4177019 YP_665287.1 CDS rpsG NC_008229.1 1365177 1365644 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(1365177..1365644) Helicobacter acinonychis str. Sheeba 4177147 YP_665288.1 CDS rpsL NC_008229.1 1365657 1366049 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(1365657..1366049) Helicobacter acinonychis str. Sheeba 4177152 YP_665289.1 CDS rpoB NC_008229.1 1366137 1374809 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; fusion of rpoB and rpoC; beta and beta' subunits are part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta/beta' complement(1366137..1374809) Helicobacter acinonychis str. Sheeba 4176863 YP_665290.1 CDS rplL NC_008229.1 1375033 1375410 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1375033..1375410) Helicobacter acinonychis str. Sheeba 4176843 YP_665291.1 CDS rplJ NC_008229.1 1375456 1375938 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1375456..1375938) Helicobacter acinonychis str. Sheeba 4176841 YP_665292.1 CDS rplA NC_008229.1 1376047 1376751 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(1376047..1376751) Helicobacter acinonychis str. Sheeba 4176834 YP_665293.1 CDS rplK NC_008229.1 1376800 1377225 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(1376800..1377225) Helicobacter acinonychis str. Sheeba 4176842 YP_665294.1 CDS nusG NC_008229.1 1377242 1377769 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(1377242..1377769) Helicobacter acinonychis str. Sheeba 4176464 YP_665295.1 CDS secE NC_008229.1 1377800 1377979 R forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(1377800..1377979) Helicobacter acinonychis str. Sheeba 4177169 YP_665296.1 CDS rpmG NC_008229.1 1378223 1378381 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(1378223..1378381) Helicobacter acinonychis str. Sheeba 4176861 YP_665297.1 CDS tuf NC_008229.1 1378418 1379617 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1378418..1379617) Helicobacter acinonychis str. Sheeba 4176676 YP_665298.1 CDS hetA NC_008229.1 1380333 1382069 D (P22638) Heterocyst differentiation ATP-binding protein hepA(P22638) Heterocyst differentiation ATP-binding protein hepA; High confidence in function and specificity; ABC transporter ATP-binding protein 1380333..1382069 Helicobacter acinonychis str. Sheeba 4177431 YP_665299.1 CDS Hac_1588 NC_008229.1 1382076 1382744 R (Q8DCT7) Phosphoglycolate phosphatase (EC 3.1.3.18) (PGP)(Q8DCT7) Phosphoglycolate phosphatase (EC 3.1.3.18) (PGP); conserved hypothetical protein; hypothetical protein complement(1382076..1382744) Helicobacter acinonychis str. Sheeba 4177347 YP_665300.1 CDS atpE NC_008229.1 1383259 1383576 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(1383259..1383576) Helicobacter acinonychis str. Sheeba 4177106 YP_665301.1 CDS pnp NC_008229.1 1383708 1385774 R (P50849) Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase) (Vegetative protein 15) (VEG15)(P50849) Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase) (Vegetative protein 15) (VEG15); High confidence in function and specificity; polynucleotide phosphorylase/polyadenylase complement(1383708..1385774) Helicobacter acinonychis str. Sheeba 4176785 YP_665302.1 CDS Hac_1592 NC_008229.1 1385777 1386481 R conserved hypothetical protein; hypothetical protein complement(1385777..1386481) Helicobacter acinonychis str. Sheeba 4177348 YP_665303.1 CDS ostA NC_008229.1 1386496 1388757 R (Q8PP22) Organic solvent tolerance protein precursor(; Function unclear; organic solvent tolerance protein complement(1386496..1388757) Helicobacter acinonychis str. Sheeba 4177332 YP_665304.1 CDS Hac_1594 NC_008229.1 1388760 1389239 R Function unclear; hypothetical protein complement(1388760..1389239) Helicobacter acinonychis str. Sheeba 4177349 YP_665305.1 CDS purD NC_008229.1 1389279 1390553 R High confidence in function and specificity; glycinamide ribonucleotide synthetase complement(1389279..1390553) Helicobacter acinonychis str. Sheeba 4177744 YP_665306.1 CDS yhcG NC_008229.1 1390829 1391515 R (P54591) Hypothetical ABC transporter ATP-binding protein yhcG(P54591) Hypothetical ABC transporter ATP-binding protein yhcG; High confidence in function and specificity; ABC transporter ATP-binding protein complement(1390829..1391515) Helicobacter acinonychis str. Sheeba 4177714 YP_665307.1 CDS uppS NC_008229.1 1391509 1392180 R catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase complement(1391509..1392180) Helicobacter acinonychis str. Sheeba 4176684 YP_665308.1 CDS dld NC_008229.1 1392256 1395096 R (Q57252) Protein HI1163(Q57252) Protein HI1163; High confidence in function and specificity; D-lactate dehydrogenase complement(1392256..1395096) Helicobacter acinonychis str. Sheeba 4177129 YP_665309.1 CDS Hac_1599 NC_008229.1 1395168 1395506 D Function unclear; hypothetical protein 1395168..1395506 Helicobacter acinonychis str. Sheeba 4177350 YP_665310.1 CDS hemD NC_008229.1 1395521 1396183 D catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 1395521..1396183 Helicobacter acinonychis str. Sheeba 4177424 YP_665311.1 CDS crcB3 NC_008229.1 1396230 1396613 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1396230..1396613 Helicobacter acinonychis str. Sheeba 4176901 YP_665312.1 CDS Hac prophage II orf1 NC_008229.1 1396754 1396894 D hypothetical protein 1396754..1396894 Helicobacter acinonychis str. Sheeba 4177582 YP_665313.1 CDS Hac prophage II orf2 NC_008229.1 1397007 1397255 D hypothetical protein 1397007..1397255 Helicobacter acinonychis str. Sheeba 4177554 YP_665314.1 CDS Hac prophage II orf3 NC_008229.1 1397361 1398497 D Function unclear; bacteriophage-related integrase 1397361..1398497 Helicobacter acinonychis str. Sheeba 4177565 YP_665315.1 CDS Hac prophage II orf4 NC_008229.1 1398497 1398673 D hypothetical protein 1398497..1398673 Helicobacter acinonychis str. Sheeba 4177569 YP_665316.1 CDS Hac prophage II orf5 NC_008229.1 1398675 1399004 D hypothetical protein 1398675..1399004 Helicobacter acinonychis str. Sheeba 4177570 YP_665317.1 CDS Hac prophage II orf6 NC_008229.1 1399001 1399948 D weak: bacteriophage-related protein; hypothetical protein; hypothetical protein 1399001..1399948 Helicobacter acinonychis str. Sheeba 4177571 YP_665318.1 CDS Hac prophage II orf7 NC_008229.1 1400146 1400415 D hypothetical protein 1400146..1400415 Helicobacter acinonychis str. Sheeba 4177572 YP_665319.1 CDS Hac prophage II orf8 NC_008229.1 1400422 1401573 D hypothetical protein CUP0976,Campylobacter upsaliensis strain RM3195,NCBI entry: 11-JAN-2005; High confidence in function and specificity; hypothetical protein 1400422..1401573 Helicobacter acinonychis str. Sheeba 4177418 YP_665320.1 CDS Hac prophage II orf9 NC_008229.1 1401586 1403157 D DNA primase DnaG (605) [Campylobacter jejuni RM1221, note: N-terminal fragment,Fouts et al. Major structural differences and novel potential virulence,mechanisms from the genomes of multiple Campylobacter species,(er) PLoS Biol. 3 (1), doi 10.1371/journal.pbio.0030040 (2005); High confidence in function and specificity; DNA primase DNA G 1401586..1403157 Helicobacter acinonychis str. Sheeba 4177419 YP_665321.1 CDS Hac prophage II orf10 NC_008229.1 1403391 1404983 D hypothetical protein 1403391..1404983 Helicobacter acinonychis str. Sheeba 4177583 YP_665322.1 CDS Hac prophage II orf11 NC_008229.1 1405053 1410272 D mosaic structure gene,CUP0956-like hypothetical protein, N-terminal,Campylobacter upsaliensis strain RM3195, gene: CUP0956 (1000),Fouts et al. Major structural differences and novel potential virulence,mechanisms from the genomes of multiple Campylobacter species,PLoS Biol. 3 (1), (2005),HP1116 C-terminal (957),jhp1044 C-terminal (1154); hypothetical protein; hypothetical protein 1405053..1410272 Helicobacter acinonychis str. Sheeba 4177584 YP_665323.1 CDS Hac prophage II orf12 NC_008229.1 1410338 1411588 D hypothetical protein 1410338..1411588 Helicobacter acinonychis str. Sheeba 4177585 YP_665324.1 CDS Hac prophage II orf13 NC_008229.1 1411585 1412157 D hypothetical protein 1411585..1412157 Helicobacter acinonychis str. Sheeba 4177586 YP_665325.1 CDS Hac prophage II orf14 NC_008229.1 1412167 1412562 D hypothetical protein 1412167..1412562 Helicobacter acinonychis str. Sheeba 4177587 YP_665326.1 CDS Hac prophage II orf15 NC_008229.1 1412559 1413146 D hypothetical protein 1412559..1413146 Helicobacter acinonychis str. Sheeba 4177588 YP_665327.1 CDS Hac prophage II orf16 NC_008229.1 1413383 1413931 D note: syntenic region Hac1620-Hac1621; CUP0940(weak)-CUP0939; hypothetical protein; hypothetical protein 1413383..1413931 Helicobacter acinonychis str. Sheeba 4177589 YP_665328.1 CDS Hac prophage II orf17 NC_008229.1 1413941 1415083 D hypothetical protein 1413941..1415083 Helicobacter acinonychis str. Sheeba 4177590 YP_665329.1 CDS Hac prophage II orf18 NC_008229.1 1415098 1415457 D hypothetical protein 1415098..1415457 Helicobacter acinonychis str. Sheeba 4177591 YP_665330.1 CDS Hac prophage II orf19 NC_008229.1 1415467 1415898 D hypothetical protein 1415467..1415898 Helicobacter acinonychis str. Sheeba 4177553 YP_665331.1 CDS Hac prophage II orf20 NC_008229.1 1415965 1417767 D mosaic structure gene, phage origin,conserved hypothetical protein ,mosaic structure gene,,CUP1551 (271), N-terminal, e-51,CUP0957 (304),C-terminal, e-53 [Campylobacter upsaliensis RM3195],Fouts et al. Major structural differences and novel potential virulence,mechanisms from the genomes of multiple Campylobacter species,PLoS Biol. 3 (1),(2005),Burkholderia cepacia phage Bcep22 gene gp50 , phage TerL (776), e-14, no mid region Summer,E.J., Cordova,M., Parkinson,B.C., Fuller,A.C.,Kitsopoulos,K., Parks,B., Rambo,L., Rothwell,S.,Mebane,L.M., Carlile,T.M., No,E.G., Gonzalez,C.M. and Young,R.F.,Complete nucleotide sequence of Bcep22, a bacteriophage isolated,from soil samples and specific for Burkholderia cepacia genomovar,III, Unpublished; hypothetical protein; hypothetical protein 1415965..1417767 Helicobacter acinonychis str. Sheeba 4177555 YP_665332.1 CDS Hac prophage II orf21 NC_008229.1 1417781 1419334 D phage-related CUP0950-like protein 1417781..1419334 Helicobacter acinonychis str. Sheeba 4177556 YP_665333.1 CDS Hac prophage II orf22 NC_008229.1 1419337 1419516 D hypothetical protein 1419337..1419516 Helicobacter acinonychis str. Sheeba 4177557 YP_665334.1 CDS Hac prophage II orf23 NC_008229.1 1419529 1419732 D hypothetical protein 1419529..1419732 Helicobacter acinonychis str. Sheeba 4177558 YP_665335.1 CDS Hac prophage II orf24 NC_008229.1 1419737 1420072 D hypothetical protein 1419737..1420072 Helicobacter acinonychis str. Sheeba 4177559 YP_665336.1 CDS Hac prophage II orf25 NC_008229.1 1420069 1420290 D hypothetical protein 1420069..1420290 Helicobacter acinonychis str. Sheeba 4177560 YP_665337.1 CDS Hac prophage II orf26 NC_008229.1 1420340 1420885 D hypothetical protein 1420340..1420885 Helicobacter acinonychis str. Sheeba 4177561 YP_665338.1 CDS Hac prophage II orf27 NC_008229.1 1420887 1421672 D Campylobacter upsaliensis RM3195 CUP0941 (248) e-08,Fouts et al. Major structural differences and novel potential virulence,mechanisms from the genomes of multiple Campylobacter species,PLoS Biol. 3 (1), (2005); hypothetical protein; hypothetical protein 1420887..1421672 Helicobacter acinonychis str. Sheeba 4177562 YP_665339.1 CDS Hac prophage II orf28 NC_008229.1 1421677 1422219 D hypothetical protein 1421677..1422219 Helicobacter acinonychis str. Sheeba 4177563 YP_665340.1 CDS Hac prophage II orf29 NC_008229.1 1422258 1422545 D hypothetical protein 1422258..1422545 Helicobacter acinonychis str. Sheeba 4177564 YP_665341.1 CDS Hac prophage II orf30 NC_008229.1 1422604 1423488 D hypothetical protein 1422604..1423488 Helicobacter acinonychis str. Sheeba 4177566 YP_665342.1 CDS Hac prophage II orf31 NC_008229.1 1423498 1424343 D hypothetical protein 1423498..1424343 Helicobacter acinonychis str. Sheeba 4177567 YP_665343.1 CDS Hac prophage II orf32 NC_008229.1 1424343 1425173 D weak CUP1445, CUP0949, CUP0949, CUP1445 e-03; hypothetical protein; hypothetical protein 1424343..1425173 Helicobacter acinonychis str. Sheeba 4177568 YP_665344.1 CDS pyrA NC_008229.1 1425609 1426748 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(1425609..1426748) Helicobacter acinonychis str. Sheeba 4177748 YP_665345.1 CDS Hac_1639 NC_008229.1 1426748 1427299 R conserved hypothetical protein; hypothetical protein complement(1426748..1427299) Helicobacter acinonychis str. Sheeba 4177351 YP_665346.1 CDS Hac_1640 NC_008229.1 1427396 1428640 R conserved hypothetical protein; integral membrane protein complement(1427396..1428640) Helicobacter acinonychis str. Sheeba 4177352 YP_665347.1 CDS Hac_1641 NC_008229.1 1428631 1429539 R (O25832) Hypothetical transport protein HP1234(O25832) Hypothetical transport protein HP1234; Specificity unclear; membrane transport protein complement(1428631..1429539) Helicobacter acinonychis str. Sheeba 4177353 YP_665348.1 CDS Hac_1642 NC_008229.1 1429735 1430196 D conserved hypothetical protein; hypothetical protein 1429735..1430196 Helicobacter acinonychis str. Sheeba 4177354 YP_665349.1 CDS folP NC_008229.1 1430294 1431436 R (P73248) Dihydropteroate synthase (EC 2.5.1.15) (DHPS) (Dihydropteroate pyrophosphorylase)(P73248) Dihydropteroate synthase (EC 2.5.1.15) (DHPS) (Dihydropteroate pyrophosphorylase); High confidence in function and specificity; dihydropteroate synthase complement(1430294..1431436) Helicobacter acinonychis str. Sheeba 4177513 YP_665350.1 CDS holB NC_008229.1 1431436 1432089 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' complement(1431436..1432089) Helicobacter acinonychis str. Sheeba 4176873 YP_665351.1 CDS Hac_1645 NC_008229.1 1432086 1432628 R conserved hypothetical protein; hypothetical protein complement(1432086..1432628) Helicobacter acinonychis str. Sheeba 4177355 YP_665352.1 CDS lysC NC_008229.1 1432625 1433842 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase complement(1432625..1433842) Helicobacter acinonychis str. Sheeba 4177629 YP_665353.1 CDS nudA NC_008229.1 1433836 1434309 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(1433836..1434309) Helicobacter acinonychis str. Sheeba 4177451 YP_665354.1 CDS Hac_1648 NC_008229.1 1434467 1434757 R High confidence in function and specificity; cytochrome c-553 complement(1434467..1434757) Helicobacter acinonychis str. Sheeba 4177356 YP_665355.1 CDS hemN NC_008229.1 1434836 1435888 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1434836..1435888 Helicobacter acinonychis str. Sheeba 4177430 YP_665356.1 CDS czcA NC_008229.1 1435925 1439029 R High confidence in function and specificity; cation efflux system protein complement(1435925..1439029) Helicobacter acinonychis str. Sheeba 4176398 YP_665357.1 CDS Hac_1651 NC_008229.1 1439032 1440030 R High confidence in function and specificity; cation efflux system protein complement(1439032..1440030) Helicobacter acinonychis str. Sheeba 4177357 YP_665358.1 CDS Hac_1652 NC_008229.1 1440027 1441271 R conserved hypothetical protein; hypothetical protein complement(1440027..1441271) Helicobacter acinonychis str. Sheeba 4176317 YP_665359.1 CDS Hac_1653 NC_008229.1 1441276 1441653 R conserved hypothetical protein; hypothetical protein complement(1441276..1441653) Helicobacter acinonychis str. Sheeba 4176318 YP_665360.1 CDS fragment 2 NC_008229.1 1442172 1443245 R hypothetical protein complement(1442172..1443245) Helicobacter acinonychis str. Sheeba 4177039 YP_665361.1 CDS fragment 1 NC_008229.1 1443214 1444566 R Probably together with 1655 part of a former gene. Contains real frameshift between 1655 and 1656.; hypothetical protein; hypothetical protein complement(1443214..1444566) Helicobacter acinonychis str. Sheeba 4177059 YP_665362.1 CDS purU NC_008229.1 1444675 1445556 R (P37051) Formyltetrahydrofolate deformylase (EC 3.5.1.10) (Formyl-FH(4) hydrolase)(P37051) Formyltetrahydrofolate deformylase (EC 3.5.1.10) (Formyl-FH(4) hydrolase); High confidence in function and specificity; formyltetrahydrofolate deformylase complement(1444675..1445556) Helicobacter acinonychis str. Sheeba 4177745 YP_665363.1 CDS pspA NC_008229.1 1445558 1446436 R (Q55682) protease slr0021 (EC 3.4.21.-)(Q55682) protease slr0021 (EC 3.4.21.-); High confidence in function and specificity; protease IV complement(1445558..1446436) Helicobacter acinonychis str. Sheeba 4177737 YP_665364.1 CDS Hac_1659 NC_008229.1 1446506 1446745 D conserved hypothetical protein; hypothetical protein 1446506..1446745 Helicobacter acinonychis str. Sheeba 4176319 YP_665365.1 CDS N-terminal fragment NC_008229.1 1446878 1447087 D hypothetical protein 1446878..1447087 Helicobacter acinonychis str. Sheeba 4177661 YP_665366.1 CDS ftsI, pbpB NC_008229.1 1447806 1449647 R High confidence in function and specificity; cell division protein FtsI complement(1447806..1449647) Helicobacter acinonychis str. Sheeba 4176529 YP_665367.1 CDS fliE NC_008229.1 1449805 1450134 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(1449805..1450134) Helicobacter acinonychis str. Sheeba 4177258 YP_665368.1 CDS flgC NC_008229.1 1450242 1450727 R with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC complement(1450242..1450727) Helicobacter acinonychis str. Sheeba 4177242 YP_665369.1 CDS flgB NC_008229.1 1450741 1451163 R with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB complement(1450741..1451163) Helicobacter acinonychis str. Sheeba 4177241 YP_665370.1 CDS ftsW NC_008229.1 1451423 1452529 D High confidence in function and specificity; cell division protein ftsW 1451423..1452529 Helicobacter acinonychis str. Sheeba 4177005 YP_665371.1 CDS ceuE NC_008229.1 1452554 1453549 R iron(III) ABC transporter periplasmic iron-binding protein complement(1452554..1453549) Helicobacter acinonychis str. Sheeba 4176597 YP_665372.1 CDS ahpC NC_008229.1 1453784 1454380 D (P21762) Probable peroxiredoxin (26 kDa antigen)(P21762) Probable peroxiredoxin (26 kDa antigen); High confidence in function and specificity; alkyl hydroperoxide reductase 1453784..1454380 Helicobacter acinonychis str. Sheeba 4177702 YP_665373.1 CDS Hac_1671 NC_008229.1 1454520 1455326 D (Q8X8V9) D-methionine-binding lipoprotein metQ precursor(Q8X8V9) D-methionine-binding lipoprotein metQ precursor; High confidence in function and specificity; ABC transporter substrate-binding protein 1454520..1455326 Helicobacter acinonychis str. Sheeba 4176320 YP_665374.1 CDS pbp2 NC_008229.1 1455438 1457180 R (P44469) Penicillin-binding protein 2 (PBP-2)(P44469) Penicillin-binding protein 2 (PBP-2); High confidence in function and specificity; penicillin-binding protein complement(1455438..1457180) Helicobacter acinonychis str. Sheeba 4176739 YP_665375.1 CDS Hac_1673 NC_008229.1 1457185 1457628 R hypothetical protein complement(1457185..1457628) Helicobacter acinonychis str. Sheeba 4176321 YP_665376.1 CDS engB NC_008229.1 1457640 1458266 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(1457640..1458266) Helicobacter acinonychis str. Sheeba 4176322 YP_665377.1 CDS Hac_1675 NC_008229.1 1458263 1458820 R (P06473) Glycoprotein B precursor(P06473) Glycoprotein B precursor; conserved hypothetical protein; hypothetical protein complement(1458263..1458820) Helicobacter acinonychis str. Sheeba 4176323 YP_665378.1 CDS Hac_1676 NC_008229.1 1458820 1459413 R (P39631) Spore coat polysaccharide biosynthesis protein spsK(P39631) Spore coat polysaccharide biosynthesis protein spsK; conserved hypothetical protein; hypothetical protein complement(1458820..1459413) Helicobacter acinonychis str. Sheeba 4176324 YP_665379.1 CDS Hac_1677 NC_008229.1 1459388 1459882 R 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (EC 3.1.3.45) (KDO 8-P phosphatase)(Q8ZLS0) 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (EC 3.1.3.45) (KDO 8-P phosphatase); High confidence in function and specificity; hypothetical protein complement(1459388..1459882) Helicobacter acinonychis str. Sheeba 4176325 YP_665380.1 CDS rlpA NC_008229.1 1459879 1460826 R RlpA-like lipoprotein precursor; High confidence in function and specificity; rare lipoprotein A complement(1459879..1460826) Helicobacter acinonychis str. Sheeba 4177092 YP_665381.1 CDS dniR NC_008229.1 1460826 1461932 R Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-) (Murein hydrolase D) (Regulatory protein dniR)Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-) (Murein hydrolase D) (Regulatory protein dniR); High confidence in function and specificity; regulatory protein DniR complement(1460826..1461932) Helicobacter acinonychis str. Sheeba 4177140 YP_665382.1 CDS Hac_1680 NC_008229.1 1462024 1462788 R (P37545) deoxyribonuclease yabD (EC 3.1.21.-)(P37545) deoxyribonuclease yabD (EC 3.1.21.-); High confidence in function and specificity; hypothetical protein complement(1462024..1462788) Helicobacter acinonychis str. Sheeba 4176326 YP_665383.1 CDS ribC NC_008229.1 1462861 1463481 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1462861..1463481 Helicobacter acinonychis str. Sheeba 4177088 YP_665384.1 CDS Hac_1682 NC_008229.1 1463482 1463754 D Flagellar biosynthetic protein flhB; Function unclear; flagellar biosynthesis protein 1463482..1463754 Helicobacter acinonychis str. Sheeba 4176327 YP_665385.1 CDS metN NC_008229.1 1463769 1464752 D part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 1463769..1464752 Helicobacter acinonychis str. Sheeba 4176217 YP_665386.1 CDS yaeE NC_008229.1 1464754 1465401 D High confidence in function and specificity; ABC transporter permease 1464754..1465401 Helicobacter acinonychis str. Sheeba 4176643 YP_665387.1 CDS Hac_1686 NC_008229.1 1465765 1467342 D attaches phosphoethanolamine to lipid A at the 1 position of the disaccharide backbone in contrast to other gram-negative bacteria; lipid A phosphoethanolamine transferase 1465765..1467342 Helicobacter acinonychis str. Sheeba 4176328 YP_665388.1 CDS Hac_1687 NC_008229.1 1467348 1467920 D inner membrane enzyme; removes 1-phosphate groups from a number of lipid A precursors which provides a point of attachment for to moieties such as phosphoethanolamine which is attached by HP0022; lipid A 1-phosphatase 1467348..1467920 Helicobacter acinonychis str. Sheeba 4176329 YP_665389.1 CDS nspC NC_008229.1 1467927 1469144 R Diaminopimelate decarboxylase (EC 4.1.1.20) (DAP decarboxylase); Function unclear; carboxynorspermidine decarboxylase complement(1467927..1469144) Helicobacter acinonychis str. Sheeba 4177449 YP_665390.1 CDS cheV NC_008229.1 1469141 1470106 R High confidence in function and specificity; chemotaxis signal transduction protein CheV complement(1469141..1470106) Helicobacter acinonychis str. Sheeba 4176602 YP_665391.1 CDS Hac_1690 NC_008229.1 1470206 1471639 R hypothetical protein complement(1470206..1471639) Helicobacter acinonychis str. Sheeba 4176330 YP_665392.1 CDS virB4 NC_008229.1 1471827 1474190 R type IV secretory pathway component VirB4 complement(1471827..1474190) Helicobacter acinonychis str. Sheeba 4176634 YP_665393.1 CDS Hac_1692 NC_008229.1 1474192 1474455 R hypothetical protein complement(1474192..1474455) Helicobacter acinonychis str. Sheeba 4176331 YP_665394.1 CDS Hac_1693 NC_008229.1 1474455 1474736 R hypothetical protein complement(1474455..1474736) Helicobacter acinonychis str. Sheeba 4176332 YP_665395.1 CDS Hac_1694 NC_008229.1 1474869 1475696 R hypothetical protein complement(1474869..1475696) Helicobacter acinonychis str. Sheeba 4176333 YP_665396.1 CDS trmU NC_008229.1 1475787 1476839 R Probable tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61)(O53271) Probable tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC 2.1.1.61); Specificity unclear; tRNA methyltransferase complement(1475787..1476839) Helicobacter acinonychis str. Sheeba 4177491 YP_665397.1 CDS dnaG NC_008229.1 1476836 1478515 R synthesizes RNA primers at the replication forks; DNA primase complement(1476836..1478515) Helicobacter acinonychis str. Sheeba 4177133 YP_665398.1 CDS groES NC_008229.1 1478795 1479151 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 1478795..1479151 Helicobacter acinonychis str. Sheeba 4177273 YP_665399.1 CDS groEL NC_008229.1 1479174 1480814 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 1479174..1480814 Helicobacter acinonychis str. Sheeba 4177272 YP_665400.1 CDS Hac_1699 NC_008229.1 1480996 1481226 D note: prediction cause plasticity zone with synteny disruption,blastn omp match; hypothetical protein; hypothetical protein 1480996..1481226 Helicobacter acinonychis str. Sheeba 4176334 YP_665401.1 CDS omp31 fragment 1 NC_008229.1 1481490 1481858 D hypothetical protein 1481490..1481858 Helicobacter acinonychis str. Sheeba 4176585 YP_665402.1 CDS omp31 fragment 2 NC_008229.1 1482474 1482815 D hypothetical protein 1482474..1482815 Helicobacter acinonychis str. Sheeba 4176586 YP_665403.1 CDS omp31 fragment 3 NC_008229.1 1482773 1482883 D hypothetical protein 1482773..1482883 Helicobacter acinonychis str. Sheeba 4176587 YP_665404.1 CDS Hac_1707 NC_008229.1 1483084 1483641 R Function unclear; hypothetical protein complement(1483084..1483641) Helicobacter acinonychis str. Sheeba 4176335 YP_665405.1 CDS Hac_1708 NC_008229.1 1483875 1484366 R hypothetical protein complement(1483875..1484366) Helicobacter acinonychis str. Sheeba 4176491 YP_665406.1 CDS Hac_1709 NC_008229.1 1484406 1484726 R hypothetical protein complement(1484406..1484726) Helicobacter acinonychis str. Sheeba 4176492 YP_665407.1 CDS Hac_1711 NC_008229.1 1484851 1485066 D hypothetical protein 1484851..1485066 Helicobacter acinonychis str. Sheeba 4176493 YP_665408.1 CDS parA NC_008229.1 1485333 1485989 D chromosome partitioning protein ParA 1485333..1485989 Helicobacter acinonychis str. Sheeba 4176736 YP_665409.1 CDS Hac_1713 NC_008229.1 1486068 1486352 D hypothetical protein 1486068..1486352 Helicobacter acinonychis str. Sheeba 4176494 YP_665410.1 CDS Hac_1714 NC_008229.1 1486396 1487574 D hypothetical protein 1486396..1487574 Helicobacter acinonychis str. Sheeba 4176495 YP_665411.1 CDS Hac_1715 NC_008229.1 1487599 1487922 R High confidence in function and specificity; hypothetical protein complement(1487599..1487922) Helicobacter acinonychis str. Sheeba 4176496 YP_665412.1 CDS Hac_1716 NC_008229.1 1488398 1489006 D Function unclear; metal-dependent hydrolase 1488398..1489006 Helicobacter acinonychis str. Sheeba 4176497 YP_665413.1 CDS ilvE NC_008229.1 1489016 1490038 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(1489016..1490038) Helicobacter acinonychis str. Sheeba 4177679 YP_665414.1 CDS omp32 NC_008229.1 1490358 1491104 R outer membrane protein 32 complement(1490358..1491104) Helicobacter acinonychis str. Sheeba 4176588 YP_665415.1 CDS polA NC_008229.1 1491205 1493868 R High confidence in function and specificity; DNA polymerase I complement(1491205..1493868) Helicobacter acinonychis str. Sheeba 4176788 YP_665416.1 CDS Hac_1720 NC_008229.1 1494176 1496500 D High confidence in function and specificity; type III restriction-modification system 1494176..1496500 Helicobacter acinonychis str. Sheeba 4176498 YP_665417.1 CDS mod NC_008229.1 1496494 1498422 D High confidence in function and specificity; type III restriction-modification system: methyltransferase 1496494..1498422 Helicobacter acinonychis str. Sheeba 4176713 YP_665418.1 CDS Hac_1723 NC_008229.1 1498632 1499216 R COG3187, HslJ, Heat shock protein [Posttranslational modification, protein turnover,chaperones],pfam03724, META, Domain of unknown function (306). Small domain family found in proteins of of unknown function. Some are secreted and implicated in motility in bacteria. Also occurs in Leishmania spp. as an essential gene. Over-expression in L.amazonensis increases virulence. A pair of cysteine residues show correlated conservation, suggesting that they form a disulphide bond.; hypothetical protein; motility protein complement(1498632..1499216) Helicobacter acinonychis str. Sheeba 4176499 YP_665419.1 CDS Hac_1724 NC_008229.1 1499223 1499894 R hypothetical protein complement(1499223..1499894) Helicobacter acinonychis str. Sheeba 4176500 YP_665420.1 CDS Hac_1725 NC_008229.1 1499897 1500712 R ABC transporter substrate-binding protein complement(1499897..1500712) Helicobacter acinonychis str. Sheeba 4176501 YP_665421.1 CDS Hac_1726 NC_008229.1 1500697 1501482 R High confidence in function and specificity; ABC transporter ATP-binding protein complement(1500697..1501482) Helicobacter acinonychis str. Sheeba 4176502 YP_665422.1 CDS Hac_1727 NC_008229.1 1501482 1502615 R Function unclear; ABC transporter permease complement(1501482..1502615) Helicobacter acinonychis str. Sheeba 4176503 YP_665423.1 CDS Hac_1728 NC_008229.1 1502768 1503424 D DUF864(Sanger) Helicobacter pylori protein of unknow; hypothetical protein; outer membrane protein 1502768..1503424 Helicobacter acinonychis str. Sheeba 4176504 YP_665424.1 CDS rbn NC_008229.1 1503455 1504273 R High confidence in function and specificity; tRNA processing ribonuclease BN complement(1503455..1504273) Helicobacter acinonychis str. Sheeba 4177066 YP_665425.1 CDS bioB NC_008229.1 1504339 1505187 R catalyzes the formation of biotin from dethiobiotin and sulfur; biotin synthase complement(1504339..1505187) Helicobacter acinonychis str. Sheeba 4177114 YP_665426.1 CDS BCGIB NC_008229.1 1505314 1506510 R High confidence in function and specificity; type IIS restriction enzyme protein complement(1505314..1506510) Helicobacter acinonychis str. Sheeba 4177111 YP_665427.1 CDS mod NC_008229.1 1506507 1508546 R High confidence in function and specificity; type II restriction modification enzyme methyltransferase complement(1506507..1508546) Helicobacter acinonychis str. Sheeba 4176714 YP_665428.1 CDS Hac_1733 NC_008229.1 1508579 1509154 R Function unclear; hypothetical protein complement(1508579..1509154) Helicobacter acinonychis str. Sheeba 4176505 YP_665429.1 CDS tmk NC_008229.1 1509142 1509717 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(1509142..1509717) Helicobacter acinonychis str. Sheeba 4177484 YP_665430.1 CDS coaD NC_008229.1 1509719 1510192 R kdtB; Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(1509719..1510192) Helicobacter acinonychis str. Sheeba 4176135 YP_665431.1 CDS ubiD NC_008229.1 1510192 1510755 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(1510192..1510755) Helicobacter acinonychis str. Sheeba 4176681 YP_665432.1 CDS flgA NC_008229.1 1510765 1511421 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1510765..1511421) Helicobacter acinonychis str. Sheeba 4177240 YP_665433.1 CDS uvrD NC_008229.1 1511418 1513463 R High confidence in function and specificity; ATP-dependent DNA helicase complement(1511418..1513463) Helicobacter acinonychis str. Sheeba 4176697 YP_665434.1 CDS Hac_1739 NC_008229.1 1513463 1516009 R Function unclear; hypothetical protein complement(1513463..1516009) Helicobacter acinonychis str. Sheeba 4176506 YP_665435.1 CDS serS NC_008229.1 1516019 1517266 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(1516019..1517266) Helicobacter acinonychis str. Sheeba 4177178 YP_665436.1 CDS Hac_1741 NC_008229.1 1517259 1518059 R Function unclear; hypothetical protein complement(1517259..1518059) Helicobacter acinonychis str. Sheeba 4176507 YP_665437.1 CDS xseB NC_008229.1 1518063 1518314 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(1518063..1518314) Helicobacter acinonychis str. Sheeba 4176642 YP_665438.1 CDS ubiE NC_008229.1 1518326 1519066 R Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase complement(1518326..1519066) Helicobacter acinonychis str. Sheeba 4176682 YP_665439.1 CDS Hac_1744 NC_008229.1 1519076 1519528 R Specificity unclear; hypothetical protein complement(1519076..1519528) Helicobacter acinonychis str. Sheeba 4176508 YP_665440.1 CDS Hac_1745 NC_008229.1 1519534 1520106 R hypothetical protein complement(1519534..1520106) Helicobacter acinonychis str. Sheeba 4176509 YP_665441.1 CDS Hac_1746 NC_008229.1 1520093 1521223 R Function unclear; ABC transporter permease complement(1520093..1521223) Helicobacter acinonychis str. Sheeba 4176510 YP_665442.1 CDS Hac_1747 NC_008229.1 1521220 1522317 R ABC transporter permease complement(1521220..1522317) Helicobacter acinonychis str. Sheeba 4177632 YP_665443.1 CDS Hac_1748 NC_008229.1 1522328 1523332 R COG1566, EmrA, Multidrug resistance efflux pump [Defense mechanisms]; Specificity unclear; hypothetical protein complement(1522328..1523332) Helicobacter acinonychis str. Sheeba 4177633 YP_665444.1 CDS Hac_1749 NC_008229.1 1523344 1524891 R hypothetical protein complement(1523344..1524891) Helicobacter acinonychis str. Sheeba 4177634 YP_665445.1 CDS Hac_1750 NC_008229.1 1524893 1526212 R (O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT(O07589) Hypothetical protein yhdT; hypothetical protein; hemolysin domain-containing protein complement(1524893..1526212) Helicobacter acinonychis str. Sheeba 4177635 YP_665446.1 CDS pit NC_008229.1 1526322 1527923 R High confidence in function and specificity; phosphate permease complement(1526322..1527923) Helicobacter acinonychis str. Sheeba 4176781 YP_665447.1 CDS Hac_1752 NC_008229.1 1528061 1528330 D Thioredoxin like.Thioredoxin like.; family membership; hypothetical protein 1528061..1528330 Helicobacter acinonychis str. Sheeba 4177636 YP_665448.1 CDS Hac_1753 NC_008229.1 1528341 1528952 D conserved hypothetical protein; hypothetical protein 1528341..1528952 Helicobacter acinonychis str. Sheeba 4177637 YP_665449.1 CDS murE NC_008229.1 1528956 1530299 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1528956..1530299 Helicobacter acinonychis str. Sheeba 4177654 YP_665450.1 CDS tal NC_008229.1 1530303 1531253 D Important for the balance of metabolites in the pentose-phosphate pathway; transaldolase 1530303..1531253 Helicobacter acinonychis str. Sheeba 4177467 YP_665451.1 CDS rplY NC_008229.1 1531308 1531844 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 1531308..1531844 Helicobacter acinonychis str. Sheeba 4176855 YP_665452.1 CDS pth NC_008229.1 1531852 1532412 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1531852..1532412 Helicobacter acinonychis str. Sheeba 4177740 YP_665453.1 CDS Hac_1758 NC_008229.1 1532422 1533489 D Membrane protein.Membrane protein.; conserved hypothetical protein; hypothetical protein 1532422..1533489 Helicobacter acinonychis str. Sheeba 4177638 YP_665454.1 CDS Hac_1759 NC_008229.1 1533672 1533896 D hypothetical protein 1533672..1533896 Helicobacter acinonychis str. Sheeba 4177639 YP_665455.1 CDS rocF NC_008229.1 1534413 1535363 R (P39138) Arginase (EC 3.5.3.1)(P39138) Arginase (EC 3.5.3.1); High confidence in function and specificity; arginase complement(1534413..1535363) Helicobacter acinonychis str. Sheeba 4176829 YP_665456.1 CDS Hac_1762 NC_008229.1 1535376 1536152 R Region start changed from 1535987 to 1536152 (165 bases); amino acid permease complement(1535376..1536152) Helicobacter acinonychis str. Sheeba 4177640 YP_665457.1 CDS rocE fragment 2 NC_008229.1 1536162 1536605 R amino acid permease complement(1536162..1536605) Helicobacter acinonychis str. Sheeba 4177100 YP_665458.1 CDS rocE fragment 1 NC_008229.1 1536593 1536727 R amino acid permease complement(1536593..1536727) Helicobacter acinonychis str. Sheeba 4177099 YP_665459.1 CDS ald NC_008229.1 1536993 1538135 D (Q99TF4) Alanine dehydrogenase 2 (EC 1.4.1.1)(Q99TF4) Alanine dehydrogenase 2 (EC 1.4.1.1); High confidence in function and specificity; hypothetical protein 1536993..1538135 Helicobacter acinonychis str. Sheeba 4177706 YP_665460.1 CDS fragment 1 NC_008229.1 1538383 1538502 D hypothetical protein 1538383..1538502 Helicobacter acinonychis str. Sheeba 4177060 YP_665461.1 CDS fragment 2 NC_008229.1 1538772 1538939 D Function unclear; hypothetical protein 1538772..1538939 Helicobacter acinonychis str. Sheeba 4177040 YP_665462.1 CDS fragment 1 NC_008229.1 1538977 1539180 D Function unclear; hypothetical protein 1538977..1539180 Helicobacter acinonychis str. Sheeba 4177061 YP_665463.1 CDS fragment 2 NC_008229.1 1539227 1539406 D Function unclear; hypothetical protein 1539227..1539406 Helicobacter acinonychis str. Sheeba 4177041 YP_665464.1 CDS omp33 NC_008229.1 1539690 1540445 R outer membrane protein 33 complement(1539690..1540445) Helicobacter acinonychis str. Sheeba 4176432 YP_665465.1 CDS ppnK NC_008229.1 1540724 1541575 D (O25944) Probable inorganic polyphosphate/ATP-NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase)(O25944) Probable inorganic polyphosphate/ATP-NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase); High confidence in function and specificity; inorganic polyphosphate/ATP-NAD kinase 1540724..1541575 Helicobacter acinonychis str. Sheeba 4176555 YP_665466.1 CDS recN NC_008229.1 1541599 1543173 D (Q9ZJ80) DNA repair protein recN (Recombination protein N)(Q9ZJ80) DNA repair protein recN (Recombination protein N); High confidence in function and specificity; DNA repair protein RecN 1541599..1543173 Helicobacter acinonychis str. Sheeba 4177071 YP_665467.1 CDS Hac_1773 NC_008229.1 1543170 1544477 D Conserved hypothetical protein. Conserved to HPyl.Conserved hypothetical protein. Conserved to HPyl.; hypothetical protein; fibronectin/fibrinogen-binding protein 1543170..1544477 Helicobacter acinonychis str. Sheeba 4177641 YP_665468.1 CDS Hac_1774 NC_008229.1 1544496 1544792 D Conserved hypothetical protein. Conserved to HPyl.Conserved hypothetical protein. Conserved to HPyl.; conserved hypothetical protein; hypothetical protein 1544496..1544792 Helicobacter acinonychis str. Sheeba 4177642 YP_665469.1 CDS dnaQ NC_008229.1 1545571 1546419 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(1545571..1546419) Helicobacter acinonychis str. Sheeba 4177137 YP_665470.1 CDS rpe NC_008229.1 1546412 1547065 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(1546412..1547065) Helicobacter acinonychis str. Sheeba 4176831 YP_665471.1 CDS fbp NC_008229.1 1547137 1548009 D catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 1547137..1548009 Helicobacter acinonychis str. Sheeba 4177417 YP_665472.1 CDS Hac_1781 NC_008229.1 1548009 1548212 D Conserved hypothetical protein. Conserved to HPyl.Conserved hypothetical protein. Conserved to HPyl.; conserved hypothetical protein; hypothetical protein 1548009..1548212 Helicobacter acinonychis str. Sheeba 4177643 YP_665473.1 CDS Hac_1782 NC_008229.1 1548227 1549123 D type II DNA methylase protein 1548227..1549123 Helicobacter acinonychis str. Sheeba 4177644 YP_665474.1 CDS Hac_1783 NC_008229.1 1549128 1549784 D Conserved hypothetical protein. Conservation to HPyl.Conserved hypothetical protein. Conservation to HPyl.; conserved hypothetical protein; hypothetical protein 1549128..1549784 Helicobacter acinonychis str. Sheeba 4177645 YP_665475.1 CDS rbn fragment NC_008229.1 1549692 1550180 R (P44608) tRNA processing ribonuclease BN (EC 3.1.-.-) (RNase BN)(P44608) tRNA processing ribonuclease BN (EC 3.1.-.-) (RNase BN); hypothetical protein; ribonuclease N fragment complement(1549692..1550180) Helicobacter acinonychis str. Sheeba 4177067 YP_665476.1 CDS bioB fragment NC_008229.1 1550246 1550518 R Fragment of (O25956) Biotin synthase (EC 2.8.1.6) (Biotin synthetase). Only C-terminal part exists.Fragment of (O25956) Biotin synthase (EC 2.8.1.6) (Biotin synthetase). Only C-terminal part exists.; High confidence in function and specificity; biotin synthetase fragment complement(1550246..1550518) Helicobacter acinonychis str. Sheeba 4177115 YP_665477.1 CDS thyX NC_008229.1 1550531 1551157 R flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase complement(1550531..1551157) Helicobacter acinonychis str. Sheeba 4177478 YP_665478.1 CDS glmS NC_008229.1 1551184 1552977 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(1551184..1552977) Helicobacter acinonychis str. Sheeba 4177767 YP_665479.1 CDS Hac_1788 NC_008229.1 1552978 1553217 R (O26059) Hypothetical protein HP1531/JHP1419; hypothetical protein; hypothetical protein complement(1552978..1553217) Helicobacter acinonychis str. Sheeba 4177646 YP_665480.1 CDS punB NC_008229.1 1553241 1553786 R (P51105) Dihydroflavonol-4-reductase (EC 1.1.1.219) (DFR) (Dihydrokaempferol 4-reductase); hypothetical protein; purine nucleoside phosphorylase complement(1553241..1553786) Helicobacter acinonychis str. Sheeba 4177741 YP_665481.1 CDS pHac1_1 NC_008230.1 234 515 D similar to JHP0828; hypothetical protein; hypothetical protein 234..515 Helicobacter acinonychis str. Sheeba 4177775 YP_665482.1 CDS pHac1_2 NC_008230.1 524 793 D similar to JHP0825; hypothetical protein; hypothetical protein 524..793 Helicobacter acinonychis str. Sheeba 4177776 YP_665483.1 CDS pHac1_3 NC_008230.1 1041 1151 R hypothetical protein complement(1041..1151) Helicobacter acinonychis str. Sheeba 4177777 YP_665484.1 CDS pHac1_4 NC_008230.1 1329 1538 R hypothetical protein complement(1329..1538) Helicobacter acinonychis str. Sheeba 4177778 YP_665485.1 CDS pHac1_5 NC_008230.1 1568 1684 R hypothetical protein complement(1568..1684) Helicobacter acinonychis str. Sheeba 4177779 YP_665486.1 CDS repA NC_008230.1 1854 3476 D replication protein repA,InterPro; Initiator RepB protein; hypothetical protein; replication A protein 1854..3476 Helicobacter acinonychis str. Sheeba 4177780 Hac_trna_0001 tRNA Hac_trna_0001 NC_008229.1 3014 3089 R tRNA-Phe complement(3014..3089) Helicobacter acinonychis str. Sheeba 4177647 Hac_trna_0002 tRNA Hac_trna_0002 NC_008229.1 214561 214636 D tRNA-Lys 214561..214636 Helicobacter acinonychis str. Sheeba 4177648 Hac_trna_0003 tRNA Hac_trna_0003 NC_008229.1 214649 214723 D tRNA-Glu 214649..214723 Helicobacter acinonychis str. Sheeba 4177649 Hac_trna_0004 tRNA Hac_trna_0004 NC_008229.1 214760 214835 D tRNA-Val 214760..214835 Helicobacter acinonychis str. Sheeba 4177650 Hac_trna_0005 tRNA Hac_trna_0005 NC_008229.1 214879 214955 D tRNA-Asp 214879..214955 Helicobacter acinonychis str. Sheeba 4176530 Hac_trna_0006 tRNA Hac_trna_0006 NC_008229.1 215015 215090 D tRNA-Glu 215015..215090 Helicobacter acinonychis str. Sheeba 4176531 Hac_trna_0007 tRNA Hac_trna_0007 NC_008229.1 260710 260784 R tRNA-Asn complement(260710..260784) Helicobacter acinonychis str. Sheeba 4176532 Hac_trna_0008 tRNA Hac_trna_0008 NC_008229.1 342648 342725 D tRNA-Met 342648..342725 Helicobacter acinonychis str. Sheeba 4176533 Hac_trna_0009 tRNA Hac_trna_0009 NC_008229.1 357516 357600 R tRNA-Leu complement(357516..357600) Helicobacter acinonychis str. Sheeba 4176534 Hac_trna_0010 tRNA Hac_trna_0010 NC_008229.1 362398 362474 D tRNA-Ile 362398..362474 Helicobacter acinonychis str. Sheeba 4176535 Hac_trna_0011 tRNA Hac_trna_0011 NC_008229.1 362491 362566 D tRNA-Ala 362491..362566 Helicobacter acinonychis str. Sheeba 4176536 Hac_trna_0012 tRNA Hac_trna_0012 NC_008229.1 417108 417185 D tRNA-Pro 417108..417185 Helicobacter acinonychis str. Sheeba 4176537 Hac_trna_0013 tRNA Hac_trna_0013 NC_008229.1 417248 417324 D tRNA-His 417248..417324 Helicobacter acinonychis str. Sheeba 4176538 Hac_trna_0014 tRNA Hac_trna_0014 NC_008229.1 417389 417465 D tRNA-Arg 417389..417465 Helicobacter acinonychis str. Sheeba 4176539 Hac_trna_0015 tRNA Hac_trna_0015 NC_008229.1 417483 417559 D tRNA-Arg 417483..417559 Helicobacter acinonychis str. Sheeba 4176540 Hac_trna_0016 tRNA Hac_trna_0016 NC_008229.1 593076 593152 D tRNA-Met 593076..593152 Helicobacter acinonychis str. Sheeba 4176541 Hac_trna_0017 tRNA Hac_trna_0017 NC_008229.1 867112 867188 R tRNA-Arg complement(867112..867188) Helicobacter acinonychis str. Sheeba 4176542 Hac_trna_0018 tRNA Hac_trna_0018 NC_008229.1 964941 965018 D tRNA-Pro 964941..965018 Helicobacter acinonychis str. Sheeba 4176543 Hac_trna_0019 tRNA Hac_trna_0019 NC_008229.1 1020044 1020131 D tRNA-Ser 1020044..1020131 Helicobacter acinonychis str. Sheeba 4176544 Hac_trna_0020 tRNA Hac_trna_0020 NC_008229.1 1041456 1041532 D tRNA-Arg 1041456..1041532 Helicobacter acinonychis str. Sheeba 4176545 Hac_trna_0021 tRNA Hac_trna_0021 NC_008229.1 1101362 1101438 R tRNA-Met complement(1101362..1101438) Helicobacter acinonychis str. Sheeba 4176546 Hac_trna_0022 tRNA Hac_trna_0022 NC_008229.1 1101467 1101541 R tRNA-Gln complement(1101467..1101541) Helicobacter acinonychis str. Sheeba 4176547 Hac_trna_0023 tRNA Hac_trna_0023 NC_008229.1 1127306 1127393 R tRNA-Ser complement(1127306..1127393) Helicobacter acinonychis str. Sheeba 4176548 Hac_trna_0024 tRNA Hac_trna_0024 NC_008229.1 1127425 1127499 R tRNA-Cys complement(1127425..1127499) Helicobacter acinonychis str. Sheeba 4176549 Hac_trna_0025 tRNA Hac_trna_0025 NC_008229.1 1127565 1127651 R tRNA-Leu complement(1127565..1127651) Helicobacter acinonychis str. Sheeba 4176199 Hac_trna_0026 tRNA Hac_trna_0026 NC_008229.1 1127884 1127958 R tRNA-Gly complement(1127884..1127958) Helicobacter acinonychis str. Sheeba 4176200 Hac_trna_0027 tRNA Hac_trna_0027 NC_008229.1 1176672 1176747 D tRNA-Ala 1176672..1176747 Helicobacter acinonychis str. Sheeba 4176201 Hac_trna_0028 tRNA Hac_trna_0028 NC_008229.1 1316308 1316399 R tRNA-Ser complement(1316308..1316399) Helicobacter acinonychis str. Sheeba 4176202 Hac_trna_0029 tRNA Hac_trna_0029 NC_008229.1 1332315 1332390 D tRNA-Val 1332315..1332390 Helicobacter acinonychis str. Sheeba 4176203 Hac_trna_0030 tRNA Hac_trna_0030 NC_008229.1 1378107 1378182 R tRNA-Trp complement(1378107..1378182) Helicobacter acinonychis str. Sheeba 4176204 Hac_trna_0031 tRNA Hac_trna_0031 NC_008229.1 1379752 1379826 R tRNA-Thr complement(1379752..1379826) Helicobacter acinonychis str. Sheeba 4176205 Hac_trna_0032 tRNA Hac_trna_0032 NC_008229.1 1379857 1379933 R tRNA-Gly complement(1379857..1379933) Helicobacter acinonychis str. Sheeba 4176206 Hac_trna_0033 tRNA Hac_trna_0033 NC_008229.1 1379950 1380034 R tRNA-Tyr complement(1379950..1380034) Helicobacter acinonychis str. Sheeba 4176207 Hac_trna_0034 tRNA Hac_trna_0034 NC_008229.1 1380062 1380137 R tRNA-Thr complement(1380062..1380137) Helicobacter acinonychis str. Sheeba 4176208 Hac_trna_0035 tRNA Hac_trna_0035 NC_008229.1 1382949 1383035 R tRNA-Leu complement(1382949..1383035) Helicobacter acinonychis str. Sheeba 4176209 Hac_trna_0036 tRNA Hac_trna_0036 NC_008229.1 1383089 1383175 R tRNA-Leu complement(1383089..1383175) Helicobacter acinonychis str. Sheeba 4176210 ST23S_rRNA_copy_I rRNA 23S rRNA copy I NC_008229.1 28755 31727 D 23S ribosomal RNA 28755..31727 Helicobacter acinonychis str. Sheeba 4176213 ST5S_rRNA_copy_I rRNA 5S rRNA copy I NC_008229.1 31952 32086 D 5S ribosomal RNA 31952..32086 Helicobacter acinonychis str. Sheeba 4176215 ST16S_rRNA_copy_I rRNA 16S rRNA copy I NC_008229.1 151802 153302 D 16S ribosomal RNA 151802..153302 Helicobacter acinonychis str. Sheeba 4176211 ST16S_rRNA_copy_II rRNA 16S rRNA copy II NC_008229.1 498579 500079 D 16S ribosomal RNA 498579..500079 Helicobacter acinonychis str. Sheeba 4176212 ST23S_rRNA_copy_II rRNA 23S rRNA copy II NC_008229.1 543239 546211 D 23S ribosomal RNA 543239..546211 Helicobacter acinonychis str. Sheeba 4176214 ST5S_rRNA_copy_II rRNA 5S rRNA copy II NC_008229.1 546436 546570 D 5S ribosomal RNA 546436..546570 Helicobacter acinonychis str. Sheeba 4176216