-- dump date   	20140619_112031
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
382638000001	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
382638000002	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638000003	Walker A motif; other site
382638000004	ATP binding site [chemical binding]; other site
382638000005	Walker B motif; other site
382638000006	arginine finger; other site
382638000007	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
382638000008	DnaA box-binding interface [nucleotide binding]; other site
382638000009	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
382638000010	active site
382638000011	putative catalytic site [active]
382638000012	DNA binding site [nucleotide binding]
382638000013	putative phosphate binding site [ion binding]; other site
382638000014	metal binding site A [ion binding]; metal-binding site
382638000015	AP binding site [nucleotide binding]; other site
382638000016	metal binding site B [ion binding]; metal-binding site
382638000017	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638000018	ATP-dependent DNA helicase RecG; Region: recG; TIGR00643
382638000019	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
382638000020	ssDNA binding site; other site
382638000021	generic binding surface II; other site
382638000022	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
382638000023	ATP binding site [chemical binding]; other site
382638000024	putative Mg++ binding site [ion binding]; other site
382638000025	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
382638000026	nucleotide binding region [chemical binding]; other site
382638000027	ATP-binding site [chemical binding]; other site
382638000028	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
382638000029	DNA methylase; Region: N6_N4_Mtase; cl17433
382638000030	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638000031	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638000032	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
382638000033	Restriction endonuclease [Defense mechanisms]; Region: COG3587
382638000034	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
382638000035	ATP binding site [chemical binding]; other site
382638000036	putative Mg++ binding site [ion binding]; other site
382638000037	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
382638000038	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
382638000039	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
382638000040	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
382638000041	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
382638000042	substrate binding site [chemical binding]; other site
382638000043	active site
382638000044	catalytic residues [active]
382638000045	heterodimer interface [polypeptide binding]; other site
382638000046	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
382638000047	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
382638000048	pyridoxal 5'-phosphate binding site [chemical binding]; other site
382638000049	catalytic residue [active]
382638000050	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
382638000051	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
382638000052	active site
382638000053	ribulose/triose binding site [chemical binding]; other site
382638000054	phosphate binding site [ion binding]; other site
382638000055	substrate (anthranilate) binding pocket [chemical binding]; other site
382638000056	product (indole) binding pocket [chemical binding]; other site
382638000057	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
382638000058	active site
382638000059	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
382638000060	anthranilate phosphoribosyltransferase; Region: trpD; TIGR01245
382638000061	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
382638000062	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
382638000063	Glutamine amidotransferase class-I; Region: GATase; pfam00117
382638000064	glutamine binding [chemical binding]; other site
382638000065	catalytic triad [active]
382638000066	anthranilate synthase component I; Provisional; Region: PRK13564
382638000067	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
382638000068	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
382638000069	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
382638000070	Sulfatase; Region: Sulfatase; cl17466
382638000071	Sulfatase; Region: Sulfatase; cl17466
382638000072	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
382638000073	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
382638000074	active site
382638000075	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
382638000076	IPP transferase; Region: IPPT; pfam01715
382638000077	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
382638000078	7-cyano-7-deazaguanine reductase; Region: QueF-II; TIGR03139
382638000079	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
382638000080	This subfamily is composed of uncharacterized bacterial glycosyltransferases in the MraY-like family. This family contains both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases, which...; Region: GT_MraY_like; cd06912
382638000081	Mg++ binding site [ion binding]; other site
382638000082	putative catalytic motif [active]
382638000083	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
382638000084	active site
382638000085	hydrophilic channel; other site
382638000086	dimerization interface [polypeptide binding]; other site
382638000087	catalytic residues [active]
382638000088	active site lid [active]
382638000089	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
382638000090	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK03946
382638000091	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638000092	Walker A/P-loop; other site
382638000093	ATP binding site [chemical binding]; other site
382638000094	Nop14-like family; Region: Nop14; pfam04147
382638000095	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638000096	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
382638000097	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
382638000098	dimer interface [polypeptide binding]; other site
382638000099	active site
382638000100	citrylCoA binding site [chemical binding]; other site
382638000101	NADH binding [chemical binding]; other site
382638000102	cationic pore residues; other site
382638000103	oxalacetate/citrate binding site [chemical binding]; other site
382638000104	coenzyme A binding site [chemical binding]; other site
382638000105	catalytic triad [active]
382638000106	isocitrate dehydrogenase; Validated; Region: PRK07362
382638000107	isocitrate dehydrogenase; Reviewed; Region: PRK07006
382638000108	Protein of unknown function (DUF1523); Region: DUF1523; pfam07509
382638000109	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
382638000110	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
382638000111	Ligand Binding Site [chemical binding]; other site
382638000112	Uncharacterized conserved protein [Function unknown]; Region: COG2127
382638000113	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
382638000114	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638000115	Walker A motif; other site
382638000116	ATP binding site [chemical binding]; other site
382638000117	Walker B motif; other site
382638000118	arginine finger; other site
382638000119	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638000120	Walker A motif; other site
382638000121	ATP binding site [chemical binding]; other site
382638000122	Walker B motif; other site
382638000123	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
382638000124	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
382638000125	tetramerization interface [polypeptide binding]; other site
382638000126	active site
382638000127	hypothetical protein; Provisional; Region: PRK03762
382638000128	PDZ domain; Region: PDZ_2; pfam13180
382638000129	protein binding site [polypeptide binding]; other site
382638000130	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
382638000131	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
382638000132	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
382638000133	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
382638000134	VirB7 interaction site; other site
382638000135	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
382638000136	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
382638000137	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
382638000138	Substrate binding site; other site
382638000139	Cupin domain; Region: Cupin_2; cl17218
382638000140	GDP-mannose 4,6-dehydratase; Region: gmd; TIGR01472
382638000141	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
382638000142	NADP-binding site; other site
382638000143	homotetramer interface [polypeptide binding]; other site
382638000144	substrate binding site [chemical binding]; other site
382638000145	homodimer interface [polypeptide binding]; other site
382638000146	active site
382638000147	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
382638000148	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
382638000149	NADP binding site [chemical binding]; other site
382638000150	active site
382638000151	putative substrate binding site [chemical binding]; other site
382638000152	prephenate dehydrogenase; Validated; Region: PRK08507
382638000153	Prephenate dehydrogenase; Region: PDH; pfam02153
382638000154	ATP-dependent protease La; Region: lon; TIGR00763
382638000155	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638000156	Walker A motif; other site
382638000157	ATP binding site [chemical binding]; other site
382638000158	Walker B motif; other site
382638000159	arginine finger; other site
382638000160	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
382638000161	Tetratricopeptide repeat; Region: TPR_18; pfam13512
382638000162	flagellar assembly protein FliW; Provisional; Region: PRK13282
382638000163	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
382638000164	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
382638000165	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
382638000166	active site
382638000167	endopeptidase Clp ATP-binding regulatory subunit (clpX); Region: clpX; TIGR00382
382638000168	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
382638000169	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
382638000170	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638000171	Walker A motif; other site
382638000172	ATP binding site [chemical binding]; other site
382638000173	Walker B motif; other site
382638000174	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
382638000175	rod shape-determining protein MreB; Provisional; Region: PRK13927
382638000176	MreB and similar proteins; Region: MreB_like; cd10225
382638000177	nucleotide binding site [chemical binding]; other site
382638000178	Mg binding site [ion binding]; other site
382638000179	putative protofilament interaction site [polypeptide binding]; other site
382638000180	RodZ interaction site [polypeptide binding]; other site
382638000181	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
382638000182	rod shape-determining protein MreC; Region: MreC; pfam04085
382638000183	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
382638000184	Sulfatase; Region: Sulfatase; cl17466
382638000185	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
382638000186	Sulfatase; Region: Sulfatase; cl17466
382638000187	transcription elongation factor NusA; Provisional; Region: nusA; PRK12328
382638000188	NusA N-terminal domain; Region: NusA_N; pfam08529
382638000189	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
382638000190	RNA binding site [nucleotide binding]; other site
382638000191	homodimer interface [polypeptide binding]; other site
382638000192	NusA-like KH domain; Region: KH_5; pfam13184
382638000193	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
382638000194	G-X-X-G motif; other site
382638000195	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
382638000196	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
382638000197	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
382638000198	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
382638000199	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
382638000200	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
382638000201	active site
382638000202	acyl-phosphate glycerol 3-phosphate acyltransferase; Region: TIGR00023
382638000203	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
382638000204	4Fe-4S binding domain; Region: Fer4_5; pfam12801
382638000205	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
382638000206	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
382638000207	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
382638000208	NAD(P) binding pocket [chemical binding]; other site
382638000209	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
382638000210	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
382638000211	catalytic motif [active]
382638000212	Zn binding site [ion binding]; other site
382638000213	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
382638000214	RibD C-terminal domain; Region: RibD_C; cl17279
382638000215	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
382638000216	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
382638000217	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
382638000218	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
382638000219	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
382638000220	metal-binding site [ion binding]
382638000221	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
382638000222	Soluble P-type ATPase [General function prediction only]; Region: COG4087
382638000223	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
382638000224	dimerization interface [polypeptide binding]; other site
382638000225	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
382638000226	ATP binding site [chemical binding]; other site
382638000227	Acylphosphatase; Region: Acylphosphatase; pfam00708
382638000228	[NiFe] hydrogenase maturation protein HypF; Region: hypF; TIGR00143
382638000229	HypF finger; Region: zf-HYPF; pfam07503
382638000230	HypF finger; Region: zf-HYPF; pfam07503
382638000231	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
382638000232	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
382638000233	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
382638000234	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
382638000235	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638000236	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
382638000237	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
382638000238	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
382638000239	substrate interaction site [chemical binding]; other site
382638000240	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
382638000241	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
382638000242	cofactor binding site; other site
382638000243	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638000244	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
382638000245	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
382638000246	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
382638000247	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
382638000248	putative active site [active]
382638000249	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
382638000250	active site
382638000251	motif I; other site
382638000252	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
382638000253	motif II; other site
382638000254	Uncharacterized conserved protein [Function unknown]; Region: COG2353
382638000255	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13904
382638000256	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
382638000257	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
382638000258	flagellum-specific ATP synthase; Validated; Region: fliI; PRK08472
382638000259	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
382638000260	Walker A motif/ATP binding site; other site
382638000261	Walker B motif; other site
382638000262	Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis [Cell motility and secretion / Intracellular trafficking and secretion]; Region: VirB11; COG0630
382638000263	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
382638000264	ATP binding site [chemical binding]; other site
382638000265	Walker A motif; other site
382638000266	hexamer interface [polypeptide binding]; other site
382638000267	Walker B motif; other site
382638000268	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
382638000269	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
382638000270	active site
382638000271	HIGH motif; other site
382638000272	nucleotide binding site [chemical binding]; other site
382638000273	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
382638000274	active site
382638000275	KMSKS motif; other site
382638000276	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
382638000277	tRNA binding surface [nucleotide binding]; other site
382638000278	anticodon binding site; other site
382638000279	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
382638000280	RNA binding surface [nucleotide binding]; other site
382638000281	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
382638000282	dimethyladenosine transferase; Region: ksgA; TIGR00755
382638000283	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
382638000284	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
382638000285	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
382638000286	KpsF/GutQ family protein; Region: kpsF; TIGR00393
382638000287	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
382638000288	putative active site [active]
382638000289	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
382638000290	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14462
382638000291	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
382638000292	FeS/SAM binding site; other site
382638000293	Maf-like protein; Reviewed; Region: PRK04056
382638000294	putative active site [active]
382638000295	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
382638000296	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
382638000297	motif 1; other site
382638000298	active site
382638000299	motif 2; other site
382638000300	motif 3; other site
382638000301	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
382638000302	DHHA1 domain; Region: DHHA1; pfam02272
382638000303	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
382638000304	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
382638000305	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
382638000306	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
382638000307	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
382638000308	active site
382638000309	PHP Thumb interface [polypeptide binding]; other site
382638000310	metal binding site [ion binding]; metal-binding site
382638000311	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
382638000312	generic binding surface I; other site
382638000313	generic binding surface II; other site
382638000314	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
382638000315	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
382638000316	RNA binding surface [nucleotide binding]; other site
382638000317	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
382638000318	active site
382638000319	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
382638000320	catalytic residues [active]
382638000321	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
382638000322	iron-sulfur cluster [ion binding]; other site
382638000323	[2Fe-2S] cluster binding site [ion binding]; other site
382638000324	fumarate hydratase; Reviewed; Region: fumC; PRK00485
382638000325	Class II fumarases; Region: Fumarase_classII; cd01362
382638000326	active site
382638000327	tetramer interface [polypeptide binding]; other site
382638000328	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
382638000329	RNA/DNA hybrid binding site [nucleotide binding]; other site
382638000330	active site
382638000331	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
382638000332	AAA domain; Region: AAA_17; pfam13207
382638000333	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
382638000334	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
382638000335	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
382638000336	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
382638000337	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
382638000338	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
382638000339	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
382638000340	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
382638000341	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
382638000342	putative translocon binding site; other site
382638000343	protein-rRNA interface [nucleotide binding]; other site
382638000344	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
382638000345	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
382638000346	G-X-X-G motif; other site
382638000347	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
382638000348	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
382638000349	23S rRNA interface [nucleotide binding]; other site
382638000350	5S rRNA interface [nucleotide binding]; other site
382638000351	putative antibiotic binding site [chemical binding]; other site
382638000352	L25 interface [polypeptide binding]; other site
382638000353	L27 interface [polypeptide binding]; other site
382638000354	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
382638000355	putative translocon interaction site; other site
382638000356	23S rRNA interface [nucleotide binding]; other site
382638000357	signal recognition particle (SRP54) interaction site; other site
382638000358	L23 interface [polypeptide binding]; other site
382638000359	trigger factor interaction site; other site
382638000360	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
382638000361	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
382638000362	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
382638000363	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
382638000364	RNA binding site [nucleotide binding]; other site
382638000365	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
382638000366	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
382638000367	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
382638000368	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
382638000369	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
382638000370	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
382638000371	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
382638000372	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
382638000373	23S rRNA interface [nucleotide binding]; other site
382638000374	5S rRNA interface [nucleotide binding]; other site
382638000375	L27 interface [polypeptide binding]; other site
382638000376	L5 interface [polypeptide binding]; other site
382638000377	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
382638000378	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
382638000379	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
382638000380	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
382638000381	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
382638000382	SecY translocase; Region: SecY; pfam00344
382638000383	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
382638000384	active site
382638000385	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
382638000386	rRNA binding site [nucleotide binding]; other site
382638000387	predicted 30S ribosome binding site; other site
382638000388	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
382638000389	30S ribosomal protein S13; Region: bact_S13; TIGR03631
382638000390	30S ribosomal protein S11; Validated; Region: PRK05309
382638000391	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
382638000392	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
382638000393	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
382638000394	RNA binding surface [nucleotide binding]; other site
382638000395	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
382638000396	alphaNTD homodimer interface [polypeptide binding]; other site
382638000397	DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type; Region: rpoA; TIGR02027
382638000398	alphaNTD - beta interaction site [polypeptide binding]; other site
382638000399	alphaNTD - beta' interaction site [polypeptide binding]; other site
382638000400	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
382638000401	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
382638000402	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
382638000403	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
382638000404	LPP20 lipoprotein; Region: LPP20; pfam02169
382638000405	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
382638000406	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
382638000407	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
382638000408	GTP/Mg2+ binding site [chemical binding]; other site
382638000409	G4 box; other site
382638000410	G5 box; other site
382638000411	trmE is a tRNA modification GTPase; Region: trmE; cd04164
382638000412	G1 box; other site
382638000413	G1 box; other site
382638000414	GTP/Mg2+ binding site [chemical binding]; other site
382638000415	Switch I region; other site
382638000416	Switch I region; other site
382638000417	G2 box; other site
382638000418	G2 box; other site
382638000419	Switch II region; other site
382638000420	G3 box; other site
382638000421	G3 box; other site
382638000422	Switch II region; other site
382638000423	G4 box; other site
382638000424	G5 box; other site
382638000425	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
382638000426	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
382638000427	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
382638000428	membrane protein insertase; Provisional; Region: PRK01318
382638000429	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
382638000430	hypothetical protein; Provisional; Region: PRK14374
382638000431	ribonuclease P protein component, eubacterial; Region: rnpA; TIGR00188
382638000432	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
382638000433	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
382638000434	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
382638000435	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
382638000436	SmpB-tmRNA interface; other site
382638000437	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK04181
382638000438	carbon storage regulator; Provisional; Region: PRK00568
382638000439	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
382638000440	active site
382638000441	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
382638000442	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638000443	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
382638000444	DNA methylase; Region: N6_N4_Mtase; cl17433
382638000445	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638000446	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
382638000447	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
382638000448	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
382638000449	active site
382638000450	phosphorylation site [posttranslational modification]
382638000451	intermolecular recognition site; other site
382638000452	dimerization interface [polypeptide binding]; other site
382638000453	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
382638000454	DNA binding site [nucleotide binding]
382638000455	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
382638000456	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
382638000457	dimer interface [polypeptide binding]; other site
382638000458	phosphorylation site [posttranslational modification]
382638000459	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
382638000460	ATP binding site [chemical binding]; other site
382638000461	Mg2+ binding site [ion binding]; other site
382638000462	G-X-G motif; other site
382638000463	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
382638000464	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
382638000465	putative substrate binding site [chemical binding]; other site
382638000466	putative ATP binding site [chemical binding]; other site
382638000467	replicative DNA helicase; Provisional; Region: PRK08506
382638000468	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
382638000469	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
382638000470	Walker A motif; other site
382638000471	ATP binding site [chemical binding]; other site
382638000472	Walker B motif; other site
382638000473	DNA binding loops [nucleotide binding]
382638000474	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
382638000475	Competence protein; Region: Competence; pfam03772
382638000476	prenyltransferase; Reviewed; Region: ubiA; PRK12874
382638000477	UbiA prenyltransferase family; Region: UbiA; pfam01040
382638000478	phosphatidylserine decarboxylase; Provisional; Region: PRK03934
382638000479	Quinolinate synthetase A protein; Region: NadA; cl00420
382638000480	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK05848
382638000481	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
382638000482	dimerization interface [polypeptide binding]; other site
382638000483	active site
382638000484	Predicted helicase [General function prediction only]; Region: COG4889
382638000485	Predicted helicase [General function prediction only]; Region: COG4889
382638000486	Nicotinamide mononucleotide transporter [Coenzyme metabolism]; Region: PnuC; COG3201
382638000487	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
382638000488	Thiamine pyrophosphokinase; Region: TPK; cd07995
382638000489	active site
382638000490	dimerization interface [polypeptide binding]; other site
382638000491	thiamine binding site [chemical binding]; other site
382638000492	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
382638000493	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
382638000494	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
382638000495	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
382638000496	active site
382638000497	substrate binding site [chemical binding]; other site
382638000498	metal binding site [ion binding]; metal-binding site
382638000499	proton-translocating NADH-quinone oxidoreductase, chain N; Region: NDH_I_N; TIGR01770
382638000500	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
382638000501	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
382638000502	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
382638000503	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
382638000504	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
382638000505	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
382638000506	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
382638000507	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
382638000508	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
382638000509	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
382638000510	4Fe-4S binding domain; Region: Fer4; cl02805
382638000511	4Fe-4S binding domain; Region: Fer4; pfam00037
382638000512	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
382638000513	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
382638000514	NADH dehydrogenase subunit G; Validated; Region: PRK08493
382638000515	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
382638000516	catalytic loop [active]
382638000517	iron binding site [ion binding]; other site
382638000518	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
382638000519	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
382638000520	molybdopterin cofactor binding site; other site
382638000521	NADH dehydrogenase subunit D; Validated; Region: PRK06075
382638000522	NADH dehydrogenase I, D subunit; Region: NuoD; TIGR01962
382638000523	NADH dehydrogenase subunit C; Provisional; Region: PRK08491
382638000524	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
382638000525	NADH dehydrogenase subunit B; Validated; Region: PRK06411
382638000526	NADH dehydrogenase subunit A; Validated; Region: PRK08489
382638000527	NAD-dependent protein deacetylases, SIR2 family [Transcription]; Region: SIR2; COG0846
382638000528	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
382638000529	NAD+ binding site [chemical binding]; other site
382638000530	substrate binding site [chemical binding]; other site
382638000531	Zn binding site [ion binding]; other site
382638000532	RDD family; Region: RDD; pfam06271
382638000533	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
382638000534	active site
382638000535	ribosome recycling factor; Reviewed; Region: frr; PRK00083
382638000536	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
382638000537	hinge region; other site
382638000538	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
382638000539	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
382638000540	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
382638000541	S-adenosylmethionine binding site [chemical binding]; other site
382638000542	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
382638000543	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
382638000544	active site
382638000545	HIGH motif; other site
382638000546	dimer interface [polypeptide binding]; other site
382638000547	KMSKS motif; other site
382638000548	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
382638000549	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
382638000550	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
382638000551	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
382638000552	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
382638000553	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
382638000554	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
382638000555	putative PBP binding loops; other site
382638000556	dimer interface [polypeptide binding]; other site
382638000557	ABC-ATPase subunit interface; other site
382638000558	Bacterial SH3 domain; Region: SH3_3; pfam08239
382638000559	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
382638000560	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
382638000561	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
382638000562	shikimate binding site; other site
382638000563	NAD(P) binding site [chemical binding]; other site
382638000564	Exoribonuclease R [Transcription]; Region: VacB; COG0557
382638000565	RNB domain; Region: RNB; pfam00773
382638000566	DNA polymerase III subunit delta; Validated; Region: PRK08487
382638000567	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
382638000568	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
382638000569	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
382638000570	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
382638000571	dimer interface [polypeptide binding]; other site
382638000572	ssDNA binding site [nucleotide binding]; other site
382638000573	tetramer (dimer of dimers) interface [polypeptide binding]; other site
382638000574	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
382638000575	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
382638000576	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
382638000577	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
382638000578	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
382638000579	putative RNA binding site [nucleotide binding]; other site
382638000580	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
382638000581	homopentamer interface [polypeptide binding]; other site
382638000582	active site
382638000583	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
382638000584	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
382638000585	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
382638000586	active site clefts [active]
382638000587	zinc binding site [ion binding]; other site
382638000588	dimer interface [polypeptide binding]; other site
382638000589	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
382638000590	active site
382638000591	dimer interface [polypeptide binding]; other site
382638000592	pantoate--beta-alanine ligase; Region: panC; TIGR00018
382638000593	Pantoate-beta-alanine ligase; Region: PanC; cd00560
382638000594	active site
382638000595	ATP-binding site [chemical binding]; other site
382638000596	pantoate-binding site; other site
382638000597	HXXH motif; other site
382638000598	Predicted branched-chain amino acid permeases (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlD; COG1687
382638000599	AzlC protein; Region: AzlC; cl00570
382638000600	chaperone protein DnaJ; Provisional; Region: PRK14288
382638000601	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
382638000602	HSP70 interaction site [polypeptide binding]; other site
382638000603	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
382638000604	substrate binding site [polypeptide binding]; other site
382638000605	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
382638000606	Zn binding sites [ion binding]; other site
382638000607	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
382638000608	dimer interface [polypeptide binding]; other site
382638000609	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
382638000610	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
382638000611	Ligand Binding Site [chemical binding]; other site
382638000612	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
382638000613	HSP70 interaction site [polypeptide binding]; other site
382638000614	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
382638000615	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
382638000616	active site
382638000617	(T/H)XGH motif; other site
382638000618	nickel responsive regulator; Provisional; Region: PRK00630
382638000619	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
382638000620	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
382638000621	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
382638000622	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
382638000623	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
382638000624	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
382638000625	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
382638000626	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
382638000627	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
382638000628	Mg2+ transporter Helicobacter pylori CorA-like subgroup; Region: HpCorA-like; cd12836
382638000629	Cl binding site [ion binding]; other site
382638000630	oligomer interface [polypeptide binding]; other site
382638000631	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
382638000632	Phosphoglycerate kinase; Region: PGK; pfam00162
382638000633	substrate binding site [chemical binding]; other site
382638000634	hinge regions; other site
382638000635	ADP binding site [chemical binding]; other site
382638000636	catalytic site [active]
382638000637	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
382638000638	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
382638000639	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
382638000640	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
382638000641	ligand binding site [chemical binding]; other site
382638000642	active site
382638000643	UGI interface [polypeptide binding]; other site
382638000644	catalytic site [active]
382638000645	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
382638000646	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
382638000647	putative acyl-acceptor binding pocket; other site
382638000648	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
382638000649	C-terminal peptidase (prc); Region: prc; TIGR00225
382638000650	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
382638000651	protein binding site [polypeptide binding]; other site
382638000652	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
382638000653	Catalytic dyad [active]
382638000654	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
382638000655	metallohydrolase, glycoprotease/Kae1 family; Region: gcp_kae1; TIGR00329
382638000656	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
382638000657	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
382638000658	cofactor binding site; other site
382638000659	DNA binding site [nucleotide binding]
382638000660	substrate interaction site [chemical binding]; other site
382638000661	elongation factor Ts; Provisional; Region: tsf; PRK09377
382638000662	UBA/TS-N domain; Region: UBA; pfam00627
382638000663	Elongation factor TS; Region: EF_TS; pfam00889
382638000664	Elongation factor TS; Region: EF_TS; pfam00889
382638000665	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
382638000666	rRNA interaction site [nucleotide binding]; other site
382638000667	S8 interaction site; other site
382638000668	putative laminin-1 binding site; other site
382638000669	putative recombination protein RecB; Provisional; Region: PRK13909
382638000670	Family description; Region: UvrD_C_2; pfam13538
382638000671	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
382638000672	pH-dependent sodium/proton antiporter; Provisional; Region: nhaA; PRK14856
382638000673	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
382638000674	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
382638000675	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
382638000676	protein-export membrane protein SecF; Region: 3a0501s07; TIGR00966
382638000677	Protein export membrane protein; Region: SecD_SecF; pfam02355
382638000678	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
382638000679	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
382638000680	HIGH motif; other site
382638000681	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
382638000682	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
382638000683	active site
382638000684	KMSKS motif; other site
382638000685	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
382638000686	tRNA binding surface [nucleotide binding]; other site
382638000687	Lipopolysaccharide-assembly; Region: LptE; pfam04390
382638000688	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
382638000689	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
382638000690	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
382638000691	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
382638000692	Peptidase family M23; Region: Peptidase_M23; pfam01551
382638000693	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
382638000694	Peptidase family M23; Region: Peptidase_M23; pfam01551
382638000695	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
382638000696	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
382638000697	transcription-repair coupling factor (mfd); Region: mfd; TIGR00580
382638000698	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
382638000699	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
382638000700	ATP binding site [chemical binding]; other site
382638000701	putative Mg++ binding site [ion binding]; other site
382638000702	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
382638000703	nucleotide binding region [chemical binding]; other site
382638000704	ATP-binding site [chemical binding]; other site
382638000705	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
382638000706	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
382638000707	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
382638000708	iron-sulfur cluster [ion binding]; other site
382638000709	[2Fe-2S] cluster binding site [ion binding]; other site
382638000710	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
382638000711	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
382638000712	intrachain domain interface; other site
382638000713	interchain domain interface [polypeptide binding]; other site
382638000714	heme bH binding site [chemical binding]; other site
382638000715	Qi binding site; other site
382638000716	heme bL binding site [chemical binding]; other site
382638000717	Qo binding site; other site
382638000718	interchain domain interface [polypeptide binding]; other site
382638000719	intrachain domain interface; other site
382638000720	Qi binding site; other site
382638000721	Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032
382638000722	Qo binding site; other site
382638000723	Cytochrome c1 [Energy production and conversion]; Region: CYT1; COG2857
382638000724	Cytochrome c; Region: Cytochrom_C; pfam00034
382638000725	Cytochrome c; Region: Cytochrom_C; cl11414
382638000726	serine O-acetyltransferase; Region: cysE; TIGR01172
382638000727	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
382638000728	trimer interface [polypeptide binding]; other site
382638000729	active site
382638000730	substrate binding site [chemical binding]; other site
382638000731	CoA binding site [chemical binding]; other site
382638000732	ICEA Protein; Region: ICEA; pfam05315
382638000733	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
382638000734	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; pfam02086
382638000735	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
382638000736	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
382638000737	Ligand binding site; other site
382638000738	oligomer interface; other site
382638000739	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
382638000740	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
382638000741	hypothetical protein; Provisional; Region: PRK04081
382638000742	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
382638000743	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3295
382638000744	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
382638000745	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
382638000746	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
382638000747	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
382638000748	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
382638000749	Class-II DAHP synthetase family; Region: DAHP_synth_2; pfam01474
382638000750	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
382638000751	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
382638000752	catalytic triad [active]
382638000753	Uncharacterized conserved protein [Function unknown]; Region: COG1556
382638000754	iron-sulfur cluster-binding protein; Region: TIGR00273
382638000755	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
382638000756	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
382638000757	Heterodisulfide reductase, subunit B [Energy production and conversion]; Region: HdrB; COG2048
382638000758	Cysteine-rich domain; Region: CCG; pfam02754
382638000759	Cysteine-rich domain; Region: CCG; pfam02754
382638000760	L-lactate transport; Region: lctP; TIGR00795
382638000761	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
382638000762	DNA glycosylase MutY; Provisional; Region: PRK13910
382638000763	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
382638000764	minor groove reading motif; other site
382638000765	helix-hairpin-helix signature motif; other site
382638000766	substrate binding pocket [chemical binding]; other site
382638000767	active site
382638000768	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
382638000769	Sodium:sulfate symporter transmembrane region; Region: Na_sulph_symp; pfam00939
382638000770	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
382638000771	Low-spin heme binding site [chemical binding]; other site
382638000772	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
382638000773	D-pathway; other site
382638000774	Putative water exit pathway; other site
382638000775	Binuclear center (active site) [active]
382638000776	K-pathway; other site
382638000777	Putative proton exit pathway; other site
382638000778	Cbb3-type cytochrome oxidase, cytochrome c subunit [Energy production and conversion]; Region: CcoO; COG2993
382638000779	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; cl01130
382638000780	cytochrome c oxidase, cbb3-type, CcoQ subunit, epsilon-Proteobacterial; Region: cbb3_Q_epsi; TIGR02736
382638000781	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
382638000782	Cytochrome c; Region: Cytochrom_C; pfam00034
382638000783	Cytochrome c; Region: Cytochrom_C; pfam00034
382638000784	Family of unknown function (DUF4006); Region: DUF4006; pfam13179
382638000785	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
382638000786	recombinase A; Provisional; Region: recA; PRK09354
382638000787	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
382638000788	hexamer interface [polypeptide binding]; other site
382638000789	Walker A motif; other site
382638000790	ATP binding site [chemical binding]; other site
382638000791	Walker B motif; other site
382638000792	enolase; Provisional; Region: eno; PRK00077
382638000793	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
382638000794	dimer interface [polypeptide binding]; other site
382638000795	metal binding site [ion binding]; metal-binding site
382638000796	substrate binding pocket [chemical binding]; other site
382638000797	AMIN domain; Region: AMIN; pfam11741
382638000798	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
382638000799	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
382638000800	ADP binding site [chemical binding]; other site
382638000801	magnesium binding site [ion binding]; other site
382638000802	putative shikimate binding site; other site
382638000803	Cache domain; Region: Cache_1; pfam02743
382638000804	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
382638000805	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
382638000806	Ligand binding site; other site
382638000807	metal-binding site
382638000808	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
382638000809	Sel1-like repeats; Region: SEL1; smart00671
382638000810	Sel1-like repeats; Region: SEL1; smart00671
382638000811	Sel1-like repeats; Region: SEL1; smart00671
382638000812	Sel1 repeat; Region: Sel1; cl02723
382638000813	Sel1-like repeats; Region: SEL1; smart00671
382638000814	Sel1-like repeats; Region: SEL1; smart00671
382638000815	hypothetical protein; Provisional; Region: PRK12378
382638000816	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
382638000817	dimer interface [polypeptide binding]; other site
382638000818	active site
382638000819	Schiff base residues; other site
382638000820	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
382638000821	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
382638000822	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
382638000823	dimer interface [polypeptide binding]; other site
382638000824	phosphorylation site [posttranslational modification]
382638000825	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
382638000826	ATP binding site [chemical binding]; other site
382638000827	Mg2+ binding site [ion binding]; other site
382638000828	G-X-G motif; other site
382638000829	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
382638000830	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
382638000831	active site
382638000832	phosphorylation site [posttranslational modification]
382638000833	intermolecular recognition site; other site
382638000834	dimerization interface [polypeptide binding]; other site
382638000835	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
382638000836	DNA binding site [nucleotide binding]
382638000837	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
382638000838	Peptidase family U32; Region: Peptidase_U32; pfam01136
382638000839	peptide chain release factor 2; Region: prfB; TIGR00020
382638000840	This domain is found in peptide chain release factors; Region: PCRF; smart00937
382638000841	RF-1 domain; Region: RF-1; pfam00472
382638000842	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
382638000843	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
382638000844	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
382638000845	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
382638000846	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
382638000847	intersubunit interface [polypeptide binding]; other site
382638000848	active site
382638000849	zinc binding site [ion binding]; other site
382638000850	Na+ binding site [ion binding]; other site
382638000851	elongation factor P; Validated; Region: PRK00529
382638000852	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
382638000853	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
382638000854	RNA binding site [nucleotide binding]; other site
382638000855	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
382638000856	RNA binding site [nucleotide binding]; other site
382638000857	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
382638000858	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
382638000859	DNA binding site [nucleotide binding]
382638000860	substrate interaction site [chemical binding]; other site
382638000861	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
382638000862	GTPase subunit of restriction endonuclease [Defense mechanisms]; Region: McrB; COG1401
382638000863	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
382638000864	Walker A motif; other site
382638000865	ATP binding site [chemical binding]; other site
382638000866	Walker B motif; other site
382638000867	LlaJI restriction endonuclease; Region: RE_LlaJI; pfam09563
382638000868	pseudaminic acid synthase; Region: PseI; TIGR03586
382638000869	NeuB family; Region: NeuB; pfam03102
382638000870	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
382638000871	NeuB binding interface [polypeptide binding]; other site
382638000872	putative substrate binding site [chemical binding]; other site
382638000873	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
382638000874	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
382638000875	Walker A/P-loop; other site
382638000876	ATP binding site [chemical binding]; other site
382638000877	Q-loop/lid; other site
382638000878	ABC transporter signature motif; other site
382638000879	Walker B; other site
382638000880	D-loop; other site
382638000881	H-loop/switch region; other site
382638000882	apolipoprotein N-acyltransferase; Reviewed; Region: PRK12291
382638000883	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
382638000884	active site
382638000885	catalytic triad [active]
382638000886	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
382638000887	Colicin V production protein; Region: Colicin_V; pfam02674
382638000888	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
382638000889	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
382638000890	dimer interface [polypeptide binding]; other site
382638000891	putative anticodon binding site; other site
382638000892	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
382638000893	motif 1; other site
382638000894	active site
382638000895	motif 2; other site
382638000896	motif 3; other site
382638000897	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
382638000898	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
382638000899	dimer interface [polypeptide binding]; other site
382638000900	active site
382638000901	glycine-pyridoxal phosphate binding site [chemical binding]; other site
382638000902	folate binding site [chemical binding]; other site
382638000903	Domain of unknown function (DUF1882); Region: DUF1882; pfam08966
382638000904	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
382638000905	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
382638000906	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
382638000907	Uncharacterized protein family, UPF0114; Region: UPF0114; cl01078
382638000908	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
382638000909	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
382638000910	putative active site [active]
382638000911	catalytic site [active]
382638000912	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
382638000913	putative active site [active]
382638000914	catalytic site [active]
382638000915	fumarate reductase iron-sulfur subunit; Provisional; Region: frdB; PRK13552
382638000916	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
382638000917	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
382638000918	fumarate reductase flavoprotein subunit; Provisional; Region: PRK08626
382638000919	L-aspartate oxidase; Provisional; Region: PRK06175
382638000920	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
382638000921	fumarate reductase cytochrome b-556 subunit; Provisional; Region: PRK13553
382638000922	Quinol:fumarate reductase (QFR) Type B subfamily, transmembrane subunit;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinone...; Region: QFR_TypeB_TM; cd00581
382638000923	Iron-sulfur protein interface; other site
382638000924	proximal heme binding site [chemical binding]; other site
382638000925	distal heme binding site [chemical binding]; other site
382638000926	dimer interface [polypeptide binding]; other site
382638000927	triosephosphate isomerase; Provisional; Region: PRK14567
382638000928	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
382638000929	substrate binding site [chemical binding]; other site
382638000930	dimer interface [polypeptide binding]; other site
382638000931	catalytic triad [active]
382638000932	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08415
382638000933	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
382638000934	NAD binding site [chemical binding]; other site
382638000935	homotetramer interface [polypeptide binding]; other site
382638000936	homodimer interface [polypeptide binding]; other site
382638000937	substrate binding site [chemical binding]; other site
382638000938	active site
382638000939	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
382638000940	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
382638000941	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
382638000942	trimer interface [polypeptide binding]; other site
382638000943	active site
382638000944	UDP-GlcNAc binding site [chemical binding]; other site
382638000945	lipid binding site [chemical binding]; lipid-binding site
382638000946	S-adenosylmethionine synthetase; Validated; Region: PRK05250
382638000947	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
382638000948	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
382638000949	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
382638000950	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
382638000951	active site
382638000952	multimer interface [polypeptide binding]; other site
382638000953	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
382638000954	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
382638000955	putative phosphate acyltransferase; Provisional; Region: PRK05331
382638000956	3-oxoacyl-(acyl-carrier-protein) synthase III; Region: fabH; TIGR00747
382638000957	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
382638000958	dimer interface [polypeptide binding]; other site
382638000959	active site
382638000960	CoA binding pocket [chemical binding]; other site
382638000961	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
382638000962	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
382638000963	active site
382638000964	zinc binding site [ion binding]; other site
382638000965	putative arabinose transporter; Provisional; Region: PRK03545
382638000966	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
382638000967	putative substrate translocation pore; other site
382638000968	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
382638000969	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
382638000970	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
382638000971	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
382638000972	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
382638000973	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
382638000974	Ligand Binding Site [chemical binding]; other site
382638000975	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
382638000976	Major Facilitator Superfamily; Region: MFS_1; pfam07690
382638000977	putative substrate translocation pore; other site
382638000978	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
382638000979	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
382638000980	Nucleoside recognition; Region: Gate; pfam07670
382638000981	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
382638000982	phosphopentomutase; Provisional; Region: PRK05362
382638000983	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
382638000984	purine-nucleoside phosphorylase, family 1 (deoD); Region: deoD; TIGR00107
382638000985	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
382638000986	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
382638000987	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
382638000988	putative substrate translocation pore; other site
382638000989	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
382638000990	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
382638000991	substrate binding pocket [chemical binding]; other site
382638000992	membrane-bound complex binding site; other site
382638000993	hinge residues; other site
382638000994	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
382638000995	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
382638000996	Walker A/P-loop; other site
382638000997	ATP binding site [chemical binding]; other site
382638000998	Q-loop/lid; other site
382638000999	ABC transporter signature motif; other site
382638001000	Walker B; other site
382638001001	D-loop; other site
382638001002	H-loop/switch region; other site
382638001003	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
382638001004	dimer interface [polypeptide binding]; other site
382638001005	conserved gate region; other site
382638001006	putative PBP binding loops; other site
382638001007	ABC-ATPase subunit interface; other site
382638001008	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
382638001009	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
382638001010	dimer interface [polypeptide binding]; other site
382638001011	conserved gate region; other site
382638001012	putative PBP binding loops; other site
382638001013	ABC-ATPase subunit interface; other site
382638001014	carbon starvation protein A; Provisional; Region: PRK15015
382638001015	Carbon starvation protein CstA; Region: CstA; pfam02554
382638001016	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
382638001017	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
382638001018	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
382638001019	dimer interface [polypeptide binding]; other site
382638001020	putative radical transfer pathway; other site
382638001021	diiron center [ion binding]; other site
382638001022	tyrosyl radical; other site
382638001023	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
382638001024	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
382638001025	S-adenosylmethionine binding site [chemical binding]; other site
382638001026	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
382638001027	Predicted permeases [General function prediction only]; Region: COG0795
382638001028	tRNA pseudouridine(38-40) synthase; Region: hisT_truA; TIGR00071
382638001029	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
382638001030	dimerization interface 3.5A [polypeptide binding]; other site
382638001031	active site
382638001032	UDP-glucose-4-epimerase GalE; Region: galE; TIGR01179
382638001033	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
382638001034	NAD binding site [chemical binding]; other site
382638001035	homodimer interface [polypeptide binding]; other site
382638001036	active site
382638001037	substrate binding site [chemical binding]; other site
382638001038	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
382638001039	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
382638001040	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
382638001041	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
382638001042	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
382638001043	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
382638001044	S-adenosylmethionine binding site [chemical binding]; other site
382638001045	primosome assembly protein PriA; Validated; Region: PRK05580
382638001046	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
382638001047	ATP binding site [chemical binding]; other site
382638001048	putative Mg++ binding site [ion binding]; other site
382638001049	helicase superfamily c-terminal domain; Region: HELICc; smart00490
382638001050	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
382638001051	excinuclease ABC subunit B; Provisional; Region: PRK05298
382638001052	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
382638001053	ATP binding site [chemical binding]; other site
382638001054	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
382638001055	putative Mg++ binding site [ion binding]; other site
382638001056	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
382638001057	nucleotide binding region [chemical binding]; other site
382638001058	ATP-binding site [chemical binding]; other site
382638001059	Ultra-violet resistance protein B; Region: UvrB; pfam12344
382638001060	UvrB/uvrC motif; Region: UVR; pfam02151
382638001061	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638001062	adenylosuccinate lyase; Provisional; Region: PRK08470
382638001063	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
382638001064	tetramer interface [polypeptide binding]; other site
382638001065	active site
382638001066	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
382638001067	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
382638001068	Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea...; Region: TPP_PFOR_porB_like; cd03376
382638001069	TPP-binding site [chemical binding]; other site
382638001070	putative dimer interface [polypeptide binding]; other site
382638001071	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
382638001072	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
382638001073	dimer interface [polypeptide binding]; other site
382638001074	PYR/PP interface [polypeptide binding]; other site
382638001075	TPP binding site [chemical binding]; other site
382638001076	substrate binding site [chemical binding]; other site
382638001077	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
382638001078	pyruvate flavodoxin oxidoreductase subunit delta; Reviewed; Region: porD; PRK09625
382638001079	4Fe-4S binding domain; Region: Fer4; pfam00037
382638001080	pyruvate flavodoxin oxidoreductase subunit gamma; Validated; Region: PRK05844
382638001081	pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; Provisional; Region: PRK14029
382638001082	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638001083	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
382638001084	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
382638001085	active site
382638001086	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
382638001087	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
382638001088	putative NAD(P) binding site [chemical binding]; other site
382638001089	putative substrate binding site [chemical binding]; other site
382638001090	catalytic Zn binding site [ion binding]; other site
382638001091	structural Zn binding site [ion binding]; other site
382638001092	dimer interface [polypeptide binding]; other site
382638001093	glucokinase, proteobacterial type; Region: glk; TIGR00749
382638001094	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
382638001095	nucleotide binding site [chemical binding]; other site
382638001096	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
382638001097	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
382638001098	putative active site [active]
382638001099	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
382638001100	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
382638001101	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
382638001102	phosphogluconate dehydratase; Validated; Region: PRK09054
382638001103	6-phosphogluconate dehydratase; Region: edd; TIGR01196
382638001104	Entner-Doudoroff aldolase; Region: eda; TIGR01182
382638001105	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
382638001106	active site
382638001107	intersubunit interface [polypeptide binding]; other site
382638001108	catalytic residue [active]
382638001109	TPR repeat; Region: TPR_11; pfam13414
382638001110	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
382638001111	binding surface
382638001112	TPR motif; other site
382638001113	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
382638001114	Sel1-like repeats; Region: SEL1; smart00671
382638001115	Sel1-like repeats; Region: SEL1; smart00671
382638001116	Sel1-like repeats; Region: SEL1; smart00671
382638001117	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
382638001118	urease subunit beta; Provisional; Region: ureB; PRK13985
382638001119	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
382638001120	subunit interactions [polypeptide binding]; other site
382638001121	active site
382638001122	flap region; other site
382638001123	urease subunit alpha; Provisional; Region: PRK13986
382638001124	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
382638001125	alpha-gamma subunit interface [polypeptide binding]; other site
382638001126	beta-gamma subunit interface [polypeptide binding]; other site
382638001127	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
382638001128	alpha-beta subunit interface [polypeptide binding]; other site
382638001129	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
382638001130	putative CheA interaction surface; other site
382638001131	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
382638001132	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
382638001133	putative binding surface; other site
382638001134	active site
382638001135	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
382638001136	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
382638001137	ATP binding site [chemical binding]; other site
382638001138	Mg2+ binding site [ion binding]; other site
382638001139	G-X-G motif; other site
382638001140	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
382638001141	Response regulator receiver domain; Region: Response_reg; pfam00072
382638001142	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
382638001143	active site
382638001144	phosphorylation site [posttranslational modification]
382638001145	intermolecular recognition site; other site
382638001146	dimerization interface [polypeptide binding]; other site
382638001147	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
382638001148	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
382638001149	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
382638001150	active site
382638001151	phosphorylation site [posttranslational modification]
382638001152	intermolecular recognition site; other site
382638001153	dimerization interface [polypeptide binding]; other site
382638001154	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
382638001155	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
382638001156	putative active site [active]
382638001157	putative metal binding site [ion binding]; other site
382638001158	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
382638001159	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
382638001160	catalytic residue [active]
382638001161	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
382638001162	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
382638001163	D-3-phosphoglycerate dehydrogenase; Region: PGDH; TIGR01327
382638001164	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
382638001165	ligand binding site [chemical binding]; other site
382638001166	NAD binding site [chemical binding]; other site
382638001167	dimerization interface [polypeptide binding]; other site
382638001168	catalytic site [active]
382638001169	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
382638001170	putative L-serine binding site [chemical binding]; other site
382638001171	ribosomal protein S1; Region: rpsA; TIGR00717
382638001172	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
382638001173	RNA binding site [nucleotide binding]; other site
382638001174	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
382638001175	RNA binding site [nucleotide binding]; other site
382638001176	S1 RNA binding domain; Region: S1; pfam00575
382638001177	RNA binding site [nucleotide binding]; other site
382638001178	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
382638001179	RNA binding site [nucleotide binding]; other site
382638001180	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
382638001181	RNA binding site [nucleotide binding]; other site
382638001182	LytB protein; Region: LYTB; pfam02401
382638001183	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
382638001184	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
382638001185	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
382638001186	hinge; other site
382638001187	active site
382638001188	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
382638001189	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
382638001190	putative tRNA-binding site [nucleotide binding]; other site
382638001191	tRNA synthetase B5 domain; Region: B5; smart00874
382638001192	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
382638001193	dimer interface [polypeptide binding]; other site
382638001194	motif 1; other site
382638001195	motif 3; other site
382638001196	motif 2; other site
382638001197	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
382638001198	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
382638001199	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
382638001200	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
382638001201	dimer interface [polypeptide binding]; other site
382638001202	motif 1; other site
382638001203	active site
382638001204	motif 2; other site
382638001205	motif 3; other site
382638001206	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
382638001207	nucleotide binding site/active site [active]
382638001208	HIT family signature motif; other site
382638001209	catalytic residue [active]
382638001210	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
382638001211	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
382638001212	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
382638001213	catalytic residue [active]
382638001214	Protein of unknown function (DUF3972); Region: DUF3972; pfam13118
382638001215	GMP synthase; Reviewed; Region: guaA; PRK00074
382638001216	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
382638001217	AMP/PPi binding site [chemical binding]; other site
382638001218	candidate oxyanion hole; other site
382638001219	catalytic triad [active]
382638001220	potential glutamine specificity residues [chemical binding]; other site
382638001221	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
382638001222	ATP Binding subdomain [chemical binding]; other site
382638001223	Ligand Binding sites [chemical binding]; other site
382638001224	Dimerization subdomain; other site
382638001225	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
382638001226	Peptidase family M48; Region: Peptidase_M48; pfam01435
382638001227	HemK family putative methylases; Region: hemK_fam; TIGR00536
382638001228	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
382638001229	glutamate dehydrogenase; Provisional; Region: PRK09414
382638001230	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
382638001231	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
382638001232	NAD(P) binding site [chemical binding]; other site
382638001233	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
382638001234	Protein of unknown function DUF262; Region: DUF262; pfam03235
382638001235	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
382638001236	phosphoserine phosphatase SerB; Region: serB; TIGR00338
382638001237	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
382638001238	motif II; other site
382638001239	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
382638001240	Ferritin-like domain; Region: Ferritin; pfam00210
382638001241	ferroxidase diiron center [ion binding]; other site
382638001242	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
382638001243	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
382638001244	SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide...; Region: SoxW; cd02951
382638001245	catalytic residues [active]
382638001246	ferrochelatase; Region: hemH; TIGR00109
382638001247	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
382638001248	C-terminal domain interface [polypeptide binding]; other site
382638001249	active site
382638001250	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
382638001251	active site
382638001252	N-terminal domain interface [polypeptide binding]; other site
382638001253	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
382638001254	RNA methyltransferase, RsmE family; Region: TIGR00046
382638001255	Methyltransferase domain; Region: Methyltransf_26; pfam13659
382638001256	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
382638001257	trimer interface [polypeptide binding]; other site
382638001258	active site
382638001259	acetyl-CoA carboxylase, biotin carboxyl carrier protein; Region: BCCP; TIGR00531
382638001260	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
382638001261	carboxyltransferase (CT) interaction site; other site
382638001262	biotinylation site [posttranslational modification]; other site
382638001263	biotin carboxylase; Validated; Region: PRK08462
382638001264	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
382638001265	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
382638001266	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
382638001267	Methyltransferase FkbM domain; Region: Methyltransf_21; cl17387
382638001268	biotin carboxylase; Validated; Region: PRK08462
382638001269	Vacuolating cyotoxin; Region: VacA; pfam02691
382638001270	Vacuolating cyotoxin; Region: VacA; pfam02691
382638001271	Vacuolating cyotoxin; Region: VacA; pfam02691
382638001272	Vacuolating cyotoxin; Region: VacA; pfam02691
382638001273	Vacuolating cyotoxin; Region: VacA; pfam02691
382638001274	Vacuolating cyotoxin; Region: VacA; pfam02691
382638001275	Vacuolating cyotoxin; Region: VacA; pfam02691
382638001276	Vacuolating cyotoxin; Region: VacA; pfam02691
382638001277	Vacuolating cyotoxin; Region: VacA; pfam02691
382638001278	Vacuolating cyotoxin; Region: VacA; pfam02691
382638001279	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
382638001280	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
382638001281	inhibitor-cofactor binding pocket; inhibition site
382638001282	pyridoxal 5'-phosphate binding site [chemical binding]; other site
382638001283	catalytic residue [active]
382638001284	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
382638001285	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638001286	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
382638001287	Clp amino terminal domain; Region: Clp_N; pfam02861
382638001288	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638001289	Walker A motif; other site
382638001290	ATP binding site [chemical binding]; other site
382638001291	Walker B motif; other site
382638001292	arginine finger; other site
382638001293	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638001294	Walker A motif; other site
382638001295	ATP binding site [chemical binding]; other site
382638001296	Walker B motif; other site
382638001297	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
382638001298	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
382638001299	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
382638001300	Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; Region: PyrC; COG0044
382638001301	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
382638001302	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
382638001303	active site
382638001304	chlorohydrolase; Provisional; Region: PRK08418
382638001305	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_D; cd01312
382638001306	active site
382638001307	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14339
382638001308	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
382638001309	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
382638001310	FeS/SAM binding site; other site
382638001311	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
382638001312	putative acyl-acceptor binding pocket; other site
382638001313	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
382638001314	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
382638001315	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
382638001316	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
382638001317	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
382638001318	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
382638001319	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
382638001320	putative active site [active]
382638001321	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
382638001322	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
382638001323	putative acyl-acceptor binding pocket; other site
382638001324	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
382638001325	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
382638001326	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3400
382638001327	TrkA-C domain; Region: TrkA_C; pfam02080
382638001328	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
382638001329	active site
382638001330	dimer interface [polypeptide binding]; other site
382638001331	metal binding site [ion binding]; metal-binding site
382638001332	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
382638001333	Mechanosensitive ion channel; Region: MS_channel; pfam00924
382638001334	radical SAM methylthiotransferase, MiaB/RimO family; Region: TIGR00089
382638001335	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
382638001336	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
382638001337	FeS/SAM binding site; other site
382638001338	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
382638001339	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638001340	Walker A motif; other site
382638001341	ATP binding site [chemical binding]; other site
382638001342	Walker B motif; other site
382638001343	arginine finger; other site
382638001344	Domain of unknown function (DUF4149); Region: DUF4149; pfam13664
382638001345	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
382638001346	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
382638001347	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
382638001348	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
382638001349	Autotransporter beta-domain; Region: Autotransporter; pfam03797
382638001350	diaminopimelate decarboxylase; Region: lysA; TIGR01048
382638001351	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
382638001352	active site
382638001353	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
382638001354	substrate binding site [chemical binding]; other site
382638001355	catalytic residues [active]
382638001356	dimer interface [polypeptide binding]; other site
382638001357	Chorismate mutase [Amino acid transport and metabolism]; Region: PheA; COG1605
382638001358	Uncharacterized conserved protein [Function unknown]; Region: COG4866
382638001359	aminodeoxychorismate synthase; Provisional; Region: PRK07508
382638001360	chorismate binding enzyme; Region: Chorismate_bind; cl10555
382638001361	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
382638001362	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
382638001363	substrate-cofactor binding pocket; other site
382638001364	pyridoxal 5'-phosphate binding site [chemical binding]; other site
382638001365	catalytic residue [active]
382638001366	acylamide amidohydrolase; Provisional; Region: amiE; PRK13286
382638001367	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
382638001368	multimer interface [polypeptide binding]; other site
382638001369	active site
382638001370	catalytic triad [active]
382638001371	dimer interface [polypeptide binding]; other site
382638001372	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK08412
382638001373	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
382638001374	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
382638001375	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
382638001376	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
382638001377	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
382638001378	peptide binding site [polypeptide binding]; other site
382638001379	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
382638001380	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
382638001381	dimer interface [polypeptide binding]; other site
382638001382	conserved gate region; other site
382638001383	putative PBP binding loops; other site
382638001384	ABC-ATPase subunit interface; other site
382638001385	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
382638001386	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
382638001387	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
382638001388	dimer interface [polypeptide binding]; other site
382638001389	conserved gate region; other site
382638001390	putative PBP binding loops; other site
382638001391	ABC-ATPase subunit interface; other site
382638001392	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
382638001393	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
382638001394	Walker A/P-loop; other site
382638001395	ATP binding site [chemical binding]; other site
382638001396	Q-loop/lid; other site
382638001397	ABC transporter signature motif; other site
382638001398	Walker B; other site
382638001399	D-loop; other site
382638001400	H-loop/switch region; other site
382638001401	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
382638001402	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
382638001403	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
382638001404	Walker A/P-loop; other site
382638001405	ATP binding site [chemical binding]; other site
382638001406	Q-loop/lid; other site
382638001407	ABC transporter signature motif; other site
382638001408	Walker B; other site
382638001409	D-loop; other site
382638001410	H-loop/switch region; other site
382638001411	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
382638001412	Obg family GTPase CgtA; Region: Obg_CgtA; TIGR02729
382638001413	GTP1/OBG; Region: GTP1_OBG; pfam01018
382638001414	Obg GTPase; Region: Obg; cd01898
382638001415	G1 box; other site
382638001416	GTP/Mg2+ binding site [chemical binding]; other site
382638001417	Switch I region; other site
382638001418	G2 box; other site
382638001419	G3 box; other site
382638001420	Switch II region; other site
382638001421	G4 box; other site
382638001422	G5 box; other site
382638001423	Alginate lyase; Region: Alginate_lyase; pfam05426
382638001424	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638001425	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
382638001426	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
382638001427	AAA domain; Region: AAA_13; pfam13166
382638001428	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
382638001429	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
382638001430	putative active site [active]
382638001431	substrate binding site [chemical binding]; other site
382638001432	putative cosubstrate binding site; other site
382638001433	catalytic site [active]
382638001434	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
382638001435	substrate binding site [chemical binding]; other site
382638001436	biotin--protein ligase; Provisional; Region: PRK08477
382638001437	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
382638001438	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
382638001439	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
382638001440	P-loop; other site
382638001441	Magnesium ion binding site [ion binding]; other site
382638001442	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
382638001443	Magnesium ion binding site [ion binding]; other site
382638001444	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
382638001445	ParB-like nuclease domain; Region: ParB; smart00470
382638001446	F0F1 ATP synthase subunit B'; Validated; Region: PRK08476
382638001447	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
382638001448	F0F1 ATP synthase subunit B; Validated; Region: PRK08475
382638001449	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
382638001450	F0F1 ATP synthase subunit delta; Provisional; Region: PRK13431
382638001451	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
382638001452	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
382638001453	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
382638001454	beta subunit interaction interface [polypeptide binding]; other site
382638001455	Walker A motif; other site
382638001456	ATP binding site [chemical binding]; other site
382638001457	Walker B motif; other site
382638001458	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
382638001459	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
382638001460	core domain interface [polypeptide binding]; other site
382638001461	delta subunit interface [polypeptide binding]; other site
382638001462	epsilon subunit interface [polypeptide binding]; other site
382638001463	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
382638001464	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
382638001465	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
382638001466	alpha subunit interaction interface [polypeptide binding]; other site
382638001467	Walker A motif; other site
382638001468	ATP binding site [chemical binding]; other site
382638001469	Walker B motif; other site
382638001470	inhibitor binding site; inhibition site
382638001471	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
382638001472	ATP synthase, F1 epsilon subunit (delta in mitochondria); Region: ATP_synt_epsi; TIGR01216
382638001473	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
382638001474	gamma subunit interface [polypeptide binding]; other site
382638001475	epsilon subunit interface [polypeptide binding]; other site
382638001476	LBP interface [polypeptide binding]; other site
382638001477	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
382638001478	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
382638001479	TolR protein; Region: tolR; TIGR02801
382638001480	TonB C terminal; Region: TonB_2; pfam13103
382638001481	translocation protein TolB; Provisional; Region: tolB; PRK04043
382638001482	TolB amino-terminal domain; Region: TolB_N; pfam04052
382638001483	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
382638001484	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
382638001485	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
382638001486	ligand binding site [chemical binding]; other site
382638001487	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
382638001488	Tetratricopeptide repeat; Region: TPR_16; pfam13432
382638001489	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
382638001490	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
382638001491	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
382638001492	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
382638001493	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
382638001494	cofactor binding site; other site
382638001495	DNA binding site [nucleotide binding]
382638001496	substrate interaction site [chemical binding]; other site
382638001497	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08471
382638001498	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
382638001499	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
382638001500	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
382638001501	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
382638001502	Sel1-like repeats; Region: SEL1; smart00671
382638001503	Sel1-like repeats; Region: SEL1; smart00671
382638001504	Sel1-like repeats; Region: SEL1; smart00671
382638001505	Sel1-like repeats; Region: SEL1; smart00671
382638001506	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
382638001507	Mechanosensitive ion channel; Region: MS_channel; pfam00924
382638001508	Mycolic acid cyclopropane synthetase; Region: CMAS; pfam02353
382638001509	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
382638001510	S-adenosylmethionine binding site [chemical binding]; other site
382638001511	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
382638001512	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
382638001513	active site
382638001514	HIGH motif; other site
382638001515	KMSKS motif; other site
382638001516	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
382638001517	anticodon binding site; other site
382638001518	tRNA binding surface [nucleotide binding]; other site
382638001519	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
382638001520	dimer interface [polypeptide binding]; other site
382638001521	putative tRNA-binding site [nucleotide binding]; other site
382638001522	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
382638001523	Methyltransferase domain; Region: Methyltransf_23; pfam13489
382638001524	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
382638001525	S-adenosylmethionine binding site [chemical binding]; other site
382638001526	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
382638001527	active site 2 [active]
382638001528	active site 1 [active]
382638001529	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
382638001530	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
382638001531	putative ADP-binding pocket [chemical binding]; other site
382638001532	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
382638001533	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
382638001534	active site
382638001535	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
382638001536	catalytic residues [active]
382638001537	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
382638001538	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
382638001539	Uncharacterized conserved protein [Function unknown]; Region: COG1479
382638001540	Protein of unknown function DUF262; Region: DUF262; pfam03235
382638001541	Protein of unknown function DUF262; Region: DUF262; pfam03235
382638001542	Mechanosensitive ion channel; Region: MS_channel; pfam00924
382638001543	Uncharacterized conserved protein [Function unknown]; Region: COG1479
382638001544	Protein of unknown function DUF262; Region: DUF262; pfam03235
382638001545	Uncharacterized conserved protein [Function unknown]; Region: COG1479
382638001546	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
382638001547	cell division protein FtsZ; Validated; Region: PRK09330
382638001548	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
382638001549	nucleotide binding site [chemical binding]; other site
382638001550	SulA interaction site; other site
382638001551	cell division protein FtsA; Region: ftsA; TIGR01174
382638001552	Cell division protein FtsA; Region: FtsA; smart00842
382638001553	Cell division protein FtsA; Region: FtsA; pfam14450
382638001554	SurA N-terminal domain; Region: SurA_N_3; cl07813
382638001555	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
382638001556	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
382638001557	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
382638001558	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
382638001559	inhibitor-cofactor binding pocket; inhibition site
382638001560	pyridoxal 5'-phosphate binding site [chemical binding]; other site
382638001561	catalytic residue [active]
382638001562	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
382638001563	putative nucleotide binding site [chemical binding]; other site
382638001564	uridine monophosphate binding site [chemical binding]; other site
382638001565	homohexameric interface [polypeptide binding]; other site
382638001566	DNA-directed RNA polymerase, subunit K/omega [Transcription]; Region: RpoZ; COG1758
382638001567	(p)ppGpp synthetase, RelA/SpoT family; Region: spoT_relA; TIGR00691
382638001568	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
382638001569	Zn2+ binding site [ion binding]; other site
382638001570	Mg2+ binding site [ion binding]; other site
382638001571	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
382638001572	synthetase active site [active]
382638001573	NTP binding site [chemical binding]; other site
382638001574	metal binding site [ion binding]; metal-binding site
382638001575	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
382638001576	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
382638001577	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
382638001578	active site
382638001579	HIGH motif; other site
382638001580	dimer interface [polypeptide binding]; other site
382638001581	KMSKS motif; other site
382638001582	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
382638001583	RNA binding surface [nucleotide binding]; other site
382638001584	Nitronate monooxygenase; Region: NMO; pfam03060
382638001585	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
382638001586	FMN binding site [chemical binding]; other site
382638001587	substrate binding site [chemical binding]; other site
382638001588	putative catalytic residue [active]
382638001589	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
382638001590	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
382638001591	active site
382638001592	metal binding site [ion binding]; metal-binding site
382638001593	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG1427
382638001594	aconitate hydratase 2; Region: acnB; TIGR00117
382638001595	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
382638001596	substrate binding site [chemical binding]; other site
382638001597	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
382638001598	substrate binding site [chemical binding]; other site
382638001599	ligand binding site [chemical binding]; other site
382638001600	flagellar biosynthetic protein FlhB; Region: flhB; TIGR00328
382638001601	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
382638001602	Z1 domain; Region: Z1; pfam10593
382638001603	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
382638001604	Flagellin N-methylase; Region: FliB; pfam03692
382638001605	signal recognition particle-docking protein FtsY; Region: ftsY; TIGR00064
382638001606	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
382638001607	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
382638001608	phosphodiesterase; Provisional; Region: PRK12704
382638001609	KH domain; Region: KH_1; pfam00013
382638001610	nucleic acid binding region [nucleotide binding]; other site
382638001611	G-X-X-G motif; other site
382638001612	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
382638001613	Zn2+ binding site [ion binding]; other site
382638001614	Mg2+ binding site [ion binding]; other site
382638001615	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
382638001616	putative efflux protein, MATE family; Region: matE; TIGR00797
382638001617	Predicted permease [General function prediction only]; Region: COG2056
382638001618	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
382638001619	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
382638001620	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
382638001621	putative active site; other site
382638001622	catalytic triad [active]
382638001623	putative dimer interface [polypeptide binding]; other site
382638001624	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
382638001625	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
382638001626	putative ATP binding site [chemical binding]; other site
382638001627	putative substrate interface [chemical binding]; other site
382638001628	flagellar biosynthetic protein FliS; Region: fliS; TIGR00208
382638001629	flagellar capping protein; Validated; Region: fliD; PRK08453
382638001630	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
382638001631	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
382638001632	flagellar protein FlaG; Provisional; Region: PRK08452
382638001633	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
382638001634	Peptidase family M23; Region: Peptidase_M23; pfam01551
382638001635	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
382638001636	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
382638001637	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
382638001638	Walker A/P-loop; other site
382638001639	ATP binding site [chemical binding]; other site
382638001640	Q-loop/lid; other site
382638001641	ABC transporter signature motif; other site
382638001642	Walker B; other site
382638001643	D-loop; other site
382638001644	H-loop/switch region; other site
382638001645	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
382638001646	S-adenosylmethionine binding site [chemical binding]; other site
382638001647	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
382638001648	Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401
382638001649	Interdomain contacts; other site
382638001650	Cytokine receptor motif; other site
382638001651	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
382638001652	Interdomain contacts; other site
382638001653	Cytokine receptor motif; other site
382638001654	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
382638001655	Interdomain contacts; other site
382638001656	Cytokine receptor motif; other site
382638001657	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
382638001658	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
382638001659	RNA binding surface [nucleotide binding]; other site
382638001660	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
382638001661	active site
382638001662	Predicted GTPase [General function prediction only]; Region: COG3596
382638001663	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
382638001664	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
382638001665	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
382638001666	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
382638001667	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
382638001668	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
382638001669	active site
382638001670	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
382638001671	nucleotide binding site/active site [active]
382638001672	HIT family signature motif; other site
382638001673	catalytic residue [active]
382638001674	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
382638001675	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
382638001676	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
382638001677	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
382638001678	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
382638001679	ATP-grasp domain; Region: ATP-grasp_4; cl17255
382638001680	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
382638001681	tetramer interfaces [polypeptide binding]; other site
382638001682	binuclear metal-binding site [ion binding]; other site
382638001683	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
382638001684	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
382638001685	catalytic residue [active]
382638001686	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236
382638001687	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
382638001688	active site
382638001689	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
382638001690	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
382638001691	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
382638001692	FeS/SAM binding site; other site
382638001693	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
382638001694	G3 box; other site
382638001695	Switch II region; other site
382638001696	G4 box; other site
382638001697	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
382638001698	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
382638001699	Ligand Binding Site [chemical binding]; other site
382638001700	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
382638001701	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
382638001702	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
382638001703	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
382638001704	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
382638001705	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
382638001706	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
382638001707	ATP-grasp domain; Region: ATP-grasp_4; cl17255
382638001708	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
382638001709	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; smart01096
382638001710	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
382638001711	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
382638001712	ATP-grasp domain; Region: ATP-grasp_4; cl17255
382638001713	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
382638001714	IMP binding site; other site
382638001715	dimer interface [polypeptide binding]; other site
382638001716	interdomain contacts; other site
382638001717	partial ornithine binding site; other site
382638001718	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
382638001719	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
382638001720	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
382638001721	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
382638001722	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
382638001723	Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153
382638001724	putative heme binding pocket [chemical binding]; other site
382638001725	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
382638001726	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
382638001727	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
382638001728	DNA methylase; Region: N6_N4_Mtase; cl17433
382638001729	DNA methylase; Region: N6_N4_Mtase; cl17433
382638001730	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
382638001731	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
382638001732	ATP binding site [chemical binding]; other site
382638001733	putative Mg++ binding site [ion binding]; other site
382638001734	Uncharacterized conserved protein [Function unknown]; Region: COG1565
382638001735	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
382638001736	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
382638001737	flagellar motor protein MotA; Validated; Region: PRK08456
382638001738	flagellar motor protein MotB; Reviewed; Region: motB; PRK08457
382638001739	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
382638001740	ligand binding site [chemical binding]; other site
382638001741	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
382638001742	dimer interface [polypeptide binding]; other site
382638001743	conserved gate region; other site
382638001744	ABC-ATPase subunit interface; other site
382638001745	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
382638001746	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
382638001747	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638001748	Walker A/P-loop; other site
382638001749	ATP binding site [chemical binding]; other site
382638001750	Q-loop/lid; other site
382638001751	ABC transporter signature motif; other site
382638001752	Walker B; other site
382638001753	D-loop; other site
382638001754	H-loop/switch region; other site
382638001755	excinuclease ABC, C subunit; Region: uvrC; TIGR00194
382638001756	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
382638001757	GIY-YIG motif/motif A; other site
382638001758	active site
382638001759	catalytic site [active]
382638001760	putative DNA binding site [nucleotide binding]; other site
382638001761	metal binding site [ion binding]; metal-binding site
382638001762	UvrB/uvrC motif; Region: UVR; pfam02151
382638001763	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
382638001764	homoserine dehydrogenase; Provisional; Region: PRK06349
382638001765	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
382638001766	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
382638001767	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
382638001768	Predicted endonuclease distantly related to archaeal Holliday junction resolvase [DNA replication, recombination, and repair]; Region: COG0792
382638001769	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
382638001770	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
382638001771	catalytic residues [active]
382638001772	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
382638001773	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
382638001774	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
382638001775	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
382638001776	Uncharacterized conserved protein [Function unknown]; Region: COG1479
382638001777	Protein of unknown function DUF262; Region: DUF262; pfam03235
382638001778	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
382638001779	Sel1-like repeats; Region: SEL1; smart00671
382638001780	Sel1-like repeats; Region: SEL1; smart00671
382638001781	Sel1 repeat; Region: Sel1; cl02723
382638001782	Sel1-like repeats; Region: SEL1; smart00671
382638001783	Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Region: DapD; COG2171
382638001784	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
382638001785	putative trimer interface [polypeptide binding]; other site
382638001786	putative CoA binding site [chemical binding]; other site
382638001787	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
382638001788	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
382638001789	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
382638001790	hypothetical protein; Provisional; Region: PRK05839
382638001791	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
382638001792	pyridoxal 5'-phosphate binding site [chemical binding]; other site
382638001793	homodimer interface [polypeptide binding]; other site
382638001794	catalytic residue [active]
382638001795	UDP-N-acetylmuramate--alanine ligase; Region: murC; TIGR01082
382638001796	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
382638001797	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
382638001798	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
382638001799	ATPase domain of DNA mismatch repair MUTS family; Region: MUTSac; smart00534
382638001800	Walker A/P-loop; other site
382638001801	ATP binding site [chemical binding]; other site
382638001802	Q-loop/lid; other site
382638001803	ABC transporter signature motif; other site
382638001804	Walker B; other site
382638001805	D-loop; other site
382638001806	H-loop/switch region; other site
382638001807	Smr domain; Region: Smr; pfam01713
382638001808	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
382638001809	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
382638001810	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
382638001811	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
382638001812	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
382638001813	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
382638001814	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
382638001815	Ni/Fe-hydrogenase, b-type cytochrome subunit; Region: CytB-hydogenase; TIGR02125
382638001816	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
382638001817	nickel binding site [ion binding]; other site
382638001818	putative substrate-binding site; other site
382638001819	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638001820	Transposase IS200 like; Region: Y1_Tnp; pfam01797
382638001821	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
382638001822	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
382638001823	Probable transposase; Region: OrfB_IS605; pfam01385
382638001824	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
382638001825	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
382638001826	Transposase IS200 like; Region: Y1_Tnp; pfam01797
382638001827	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
382638001828	Major Facilitator Superfamily; Region: MFS_1; pfam07690
382638001829	putative substrate translocation pore; other site
382638001830	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
382638001831	Ligand Binding Site [chemical binding]; other site
382638001832	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
382638001833	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
382638001834	active site
382638001835	NTP binding site [chemical binding]; other site
382638001836	metal binding triad [ion binding]; metal-binding site
382638001837	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
382638001838	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
382638001839	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
382638001840	FMN binding site [chemical binding]; other site
382638001841	active site
382638001842	catalytic residues [active]
382638001843	substrate binding site [chemical binding]; other site
382638001844	LysE type translocator; Region: LysE; cl00565
382638001845	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
382638001846	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
382638001847	acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Region: accA; TIGR00513
382638001848	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
382638001849	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK08439
382638001850	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
382638001851	dimer interface [polypeptide binding]; other site
382638001852	active site
382638001853	acyl carrier protein; Provisional; Region: acpP; PRK00982
382638001854	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
382638001855	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
382638001856	NAD(P) binding site [chemical binding]; other site
382638001857	active site
382638001858	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
382638001859	Predicted membrane protein [Function unknown]; Region: COG3059
382638001860	diaminopimelate epimerase; Region: DapF; TIGR00652
382638001861	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
382638001862	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
382638001863	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
382638001864	Domain of unknown function DUF20; Region: UPF0118; pfam01594
382638001865	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
382638001866	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
382638001867	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
382638001868	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
382638001869	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
382638001870	putative substrate translocation pore; other site
382638001871	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
382638001872	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
382638001873	active site
382638001874	metal binding site [ion binding]; metal-binding site
382638001875	H(+) -translocating inorganic pyrophosphatase; Region: PLN02255; cl11452
382638001876	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
382638001877	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
382638001878	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
382638001879	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
382638001880	Inactivated superfamily I helicase [DNA replication, recombination, and repair]; Region: COG3893
382638001881	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
382638001882	transketolase, bacterial and yeast; Region: tktlase_bact; TIGR00232
382638001883	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
382638001884	TPP-binding site [chemical binding]; other site
382638001885	dimer interface [polypeptide binding]; other site
382638001886	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
382638001887	PYR/PP interface [polypeptide binding]; other site
382638001888	dimer interface [polypeptide binding]; other site
382638001889	TPP binding site [chemical binding]; other site
382638001890	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
382638001891	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
382638001892	riboflavin kinase/FMN adenylyltransferase; Region: ribF; TIGR00083
382638001893	active site
382638001894	Riboflavin kinase; Region: Flavokinase; pfam01687
382638001895	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
382638001896	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
382638001897	RNA binding surface [nucleotide binding]; other site
382638001898	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
382638001899	S-adenosylmethionine binding site [chemical binding]; other site
382638001900	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
382638001901	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
382638001902	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
382638001903	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
382638001904	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
382638001905	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
382638001906	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
382638001907	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638001908	Walker A/P-loop; other site
382638001909	ATP binding site [chemical binding]; other site
382638001910	Q-loop/lid; other site
382638001911	ABC transporter signature motif; other site
382638001912	Walker B; other site
382638001913	D-loop; other site
382638001914	H-loop/switch region; other site
382638001915	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
382638001916	Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes [Defense mechanisms]; Region: COG1787
382638001917	Restriction endonuclease; Region: Mrr_cat; pfam04471
382638001918	Cation transport protein; Region: TrkH; cl17365
382638001919	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
382638001920	TrkA-N domain; Region: TrkA_N; pfam02254
382638001921	TrkA-C domain; Region: TrkA_C; pfam02080
382638001922	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
382638001923	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
382638001924	phospho-N-acetylmuramoyl-pentapeptide-transferase; Region: mraY; TIGR00445
382638001925	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
382638001926	Mg++ binding site [ion binding]; other site
382638001927	putative catalytic motif [active]
382638001928	putative substrate binding site [chemical binding]; other site
382638001929	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03815
382638001930	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
382638001931	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
382638001932	Protein of unknown function (DUF493); Region: DUF493; pfam04359
382638001933	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
382638001934	active site
382638001935	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
382638001936	Na2 binding site [ion binding]; other site
382638001937	putative substrate binding site 1 [chemical binding]; other site
382638001938	Na binding site 1 [ion binding]; other site
382638001939	putative substrate binding site 2 [chemical binding]; other site
382638001940	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
382638001941	putative substrate binding site 1 [chemical binding]; other site
382638001942	Na binding site 1 [ion binding]; other site
382638001943	putative substrate binding site 2 [chemical binding]; other site
382638001944	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
382638001945	Na binding site [ion binding]; other site
382638001946	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cl00248
382638001947	substrate binding site [chemical binding]; other site
382638001948	dimerization interface [polypeptide binding]; other site
382638001949	active site
382638001950	calcium binding site [ion binding]; other site
382638001951	DNA polymerase III, beta subunit; Region: dnan; TIGR00663
382638001952	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
382638001953	putative DNA binding surface [nucleotide binding]; other site
382638001954	dimer interface [polypeptide binding]; other site
382638001955	beta-clamp/translesion DNA polymerase binding surface; other site
382638001956	beta-clamp/clamp loader binding surface; other site
382638001957	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
382638001958	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
382638001959	Mg2+ binding site [ion binding]; other site
382638001960	G-X-G motif; other site
382638001961	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
382638001962	anchoring element; other site
382638001963	dimer interface [polypeptide binding]; other site
382638001964	ATP binding site [chemical binding]; other site
382638001965	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
382638001966	active site
382638001967	putative metal-binding site [ion binding]; other site
382638001968	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
382638001969	R.Pab1 restriction endonuclease; Region: RE_R_Pab1; pfam09522
382638001970	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638001971	RNA methyltransferase, RsmD family; Region: TIGR00095
382638001972	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
382638001973	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK08455
382638001974	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
382638001975	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
382638001976	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
382638001977	nucleotide binding pocket [chemical binding]; other site
382638001978	K-X-D-G motif; other site
382638001979	catalytic site [active]
382638001980	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
382638001981	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
382638001982	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
382638001983	Dimer interface [polypeptide binding]; other site
382638001984	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
382638001985	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
382638001986	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
382638001987	active site
382638001988	phosphorylation site [posttranslational modification]
382638001989	intermolecular recognition site; other site
382638001990	dimerization interface [polypeptide binding]; other site
382638001991	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
382638001992	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
382638001993	dimer interface [polypeptide binding]; other site
382638001994	anticodon binding site; other site
382638001995	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
382638001996	homodimer interface [polypeptide binding]; other site
382638001997	motif 1; other site
382638001998	active site
382638001999	motif 2; other site
382638002000	GAD domain; Region: GAD; pfam02938
382638002001	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
382638002002	active site
382638002003	motif 3; other site
382638002004	adenylate kinase; Reviewed; Region: adk; PRK00279
382638002005	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
382638002006	AMP-binding site [chemical binding]; other site
382638002007	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
382638002008	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
382638002009	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
382638002010	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
382638002011	dimer interface [polypeptide binding]; other site
382638002012	substrate binding site [chemical binding]; other site
382638002013	metal binding sites [ion binding]; metal-binding site
382638002014	hypothetical protein; Provisional; Region: PRK08444
382638002015	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
382638002016	FeS/SAM binding site; other site
382638002017	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
382638002018	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
382638002019	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
382638002020	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
382638002021	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
382638002022	Surface antigen; Region: Bac_surface_Ag; pfam01103
382638002023	hypothetical protein; Provisional; Region: PRK08445
382638002024	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
382638002025	FeS/SAM binding site; other site
382638002026	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
382638002027	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
382638002028	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
382638002029	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
382638002030	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
382638002031	GatB domain; Region: GatB_Yqey; smart00845
382638002032	SurA N-terminal domain; Region: SurA_N; pfam09312
382638002033	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
382638002034	Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module [General function prediction only]; Region: COG1439
382638002035	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
382638002036	RNA/DNA hybrid binding site [nucleotide binding]; other site
382638002037	active site
382638002038	ribonuclease III; Reviewed; Region: rnc; PRK00102
382638002039	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
382638002040	dimerization interface [polypeptide binding]; other site
382638002041	active site
382638002042	metal binding site [ion binding]; metal-binding site
382638002043	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
382638002044	dsRNA binding site [nucleotide binding]; other site
382638002045	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
382638002046	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
382638002047	Tetramer interface [polypeptide binding]; other site
382638002048	active site
382638002049	FMN-binding site [chemical binding]; other site
382638002050	Protein of unknown function (DUF2603); Region: DUF2603; pfam10788
382638002051	oxygen-independent coproporphyrinogen III oxidase; Region: hemN; TIGR00538
382638002052	HemN C-terminal domain; Region: HemN_C; pfam06969
382638002053	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
382638002054	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
382638002055	Cysteine-rich domain; Region: CCG; pfam02754
382638002056	Cysteine-rich domain; Region: CCG; pfam02754
382638002057	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
382638002058	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002059	aspartate aminotransferase; Provisional; Region: PRK05764
382638002060	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
382638002061	pyridoxal 5'-phosphate binding site [chemical binding]; other site
382638002062	homodimer interface [polypeptide binding]; other site
382638002063	catalytic residue [active]
382638002064	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
382638002065	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
382638002066	active site
382638002067	DNA binding site [nucleotide binding]
382638002068	Int/Topo IB signature motif; other site
382638002069	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
382638002070	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
382638002071	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
382638002072	DNA binding site [nucleotide binding]
382638002073	active site
382638002074	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
382638002075	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
382638002076	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
382638002077	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
382638002078	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08447
382638002079	ATP cone domain; Region: ATP-cone; pfam03477
382638002080	Class I ribonucleotide reductase; Region: RNR_I; cd01679
382638002081	active site
382638002082	dimer interface [polypeptide binding]; other site
382638002083	catalytic residues [active]
382638002084	effector binding site; other site
382638002085	R2 peptide binding site; other site
382638002086	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14359
382638002087	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
382638002088	Substrate binding site; other site
382638002089	Mg++ binding site; other site
382638002090	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
382638002091	active site
382638002092	substrate binding site [chemical binding]; other site
382638002093	CoA binding site [chemical binding]; other site
382638002094	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
382638002095	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
382638002096	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
382638002097	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
382638002098	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
382638002099	G1 box; other site
382638002100	GTP/Mg2+ binding site [chemical binding]; other site
382638002101	Switch I region; other site
382638002102	G2 box; other site
382638002103	G3 box; other site
382638002104	Switch II region; other site
382638002105	G4 box; other site
382638002106	G5 box; other site
382638002107	Nucleoside recognition; Region: Gate; pfam07670
382638002108	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
382638002109	Nucleoside recognition; Region: Gate; pfam07670
382638002110	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
382638002111	active site
382638002112	catalytic site [active]
382638002113	substrate binding site [chemical binding]; other site
382638002114	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108
382638002115	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
382638002116	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
382638002117	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
382638002118	Predicted methyltransferases [General function prediction only]; Region: COG0313
382638002119	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
382638002120	putative SAM binding site [chemical binding]; other site
382638002121	putative homodimer interface [polypeptide binding]; other site
382638002122	Ribosomal protein L31; Region: Ribosomal_L31; pfam01197
382638002123	transcription termination factor Rho; Provisional; Region: rho; PRK09376
382638002124	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
382638002125	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
382638002126	RNA binding site [nucleotide binding]; other site
382638002127	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
382638002128	multimer interface [polypeptide binding]; other site
382638002129	Walker A motif; other site
382638002130	ATP binding site [chemical binding]; other site
382638002131	Walker B motif; other site
382638002132	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
382638002133	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
382638002134	Sel1-like repeats; Region: SEL1; smart00671
382638002135	glutamine synthetase, type I; Region: GlnA; TIGR00653
382638002136	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
382638002137	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
382638002138	Uncharacterized conserved protein [Function unknown]; Region: COG1479
382638002139	Protein of unknown function DUF262; Region: DUF262; pfam03235
382638002140	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
382638002141	Uncharacterized conserved protein [Function unknown]; Region: COG3586
382638002142	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
382638002143	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
382638002144	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
382638002145	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
382638002146	active site
382638002147	HslU subunit interaction site [polypeptide binding]; other site
382638002148	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
382638002149	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638002150	Walker A motif; other site
382638002151	ATP binding site [chemical binding]; other site
382638002152	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638002153	Walker B motif; other site
382638002154	arginine finger; other site
382638002155	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
382638002156	GTPase Era; Reviewed; Region: era; PRK00089
382638002157	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
382638002158	G1 box; other site
382638002159	GTP/Mg2+ binding site [chemical binding]; other site
382638002160	Switch I region; other site
382638002161	G2 box; other site
382638002162	Switch II region; other site
382638002163	G3 box; other site
382638002164	G4 box; other site
382638002165	G5 box; other site
382638002166	KH domain; Region: KH_2; pfam07650
382638002167	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
382638002168	dihydrodipicolinate reductase; Region: dapB; TIGR00036
382638002169	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
382638002170	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
382638002171	FAD binding domain; Region: FAD_binding_4; pfam01565
382638002172	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
382638002173	Protein-interacting Bro1-like domain of mammalian Alix and related domains; Region: BRO1_Alix_like; cl14649
382638002174	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
382638002175	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
382638002176	dimer interface [polypeptide binding]; other site
382638002177	ADP-ribose binding site [chemical binding]; other site
382638002178	active site
382638002179	nudix motif; other site
382638002180	metal binding site [ion binding]; metal-binding site
382638002181	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
382638002182	Peptidase family M23; Region: Peptidase_M23; pfam01551
382638002183	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
382638002184	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
382638002185	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
382638002186	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
382638002187	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
382638002188	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
382638002189	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
382638002190	nucleotide binding region [chemical binding]; other site
382638002191	ATP-binding site [chemical binding]; other site
382638002192	SEC-C motif; Region: SEC-C; pfam02810
382638002193	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
382638002194	FtsX-like permease family; Region: FtsX; pfam02687
382638002195	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
382638002196	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
382638002197	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
382638002198	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207
382638002199	metal-binding site [ion binding]
382638002200	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
382638002201	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
382638002202	Soluble P-type ATPase [General function prediction only]; Region: COG4087
382638002203	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
382638002204	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
382638002205	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
382638002206	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
382638002207	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
382638002208	active site
382638002209	catalytic residues [active]
382638002210	metal binding site [ion binding]; metal-binding site
382638002211	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
382638002212	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
382638002213	oligomer interface [polypeptide binding]; other site
382638002214	active site residues [active]
382638002215	trigger factor; Provisional; Region: tig; PRK01490
382638002216	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
382638002217	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
382638002218	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002219	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
382638002220	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
382638002221	dimerization interface [polypeptide binding]; other site
382638002222	active site
382638002223	Domain of unknown function (DUF3943); Region: DUF3943; pfam13084
382638002224	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09314
382638002225	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
382638002226	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cl00522
382638002227	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
382638002228	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
382638002229	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
382638002230	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
382638002231	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
382638002232	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
382638002233	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002234	MraW methylase family; Region: Methyltransf_5; cl17771
382638002235	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
382638002236	Uncharacterized conserved protein [Function unknown]; Region: COG1912
382638002237	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
382638002238	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
382638002239	Fic/DOC family; Region: Fic; pfam02661
382638002240	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
382638002241	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
382638002242	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
382638002243	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
382638002244	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
382638002245	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
382638002246	Walker A/P-loop; other site
382638002247	ATP binding site [chemical binding]; other site
382638002248	Q-loop/lid; other site
382638002249	ABC transporter signature motif; other site
382638002250	Walker B; other site
382638002251	D-loop; other site
382638002252	H-loop/switch region; other site
382638002253	tRNA threonylcarbamoyl adenosine modification protein YjeE; Region: T6A_YjeE; TIGR00150
382638002254	DNA polymerase III subunits gamma and tau; Validated; Region: PRK08451
382638002255	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638002256	Walker A motif; other site
382638002257	ATP binding site [chemical binding]; other site
382638002258	Walker B motif; other site
382638002259	arginine finger; other site
382638002260	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002261	Anaerobic c4-dicarboxylate membrane transporter; Region: DcuA_DcuB; cl01040
382638002262	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
382638002263	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
382638002264	active site
382638002265	homotetramer interface [polypeptide binding]; other site
382638002266	homodimer interface [polypeptide binding]; other site
382638002267	Acetone carboxylase, gamma subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcxC; COG4647
382638002268	Acetone carboxylase gamma subunit; Region: Acetone_carb_G; pfam08882
382638002269	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
382638002270	Hydantoinase B/oxoprolinase; Region: Hydantoinase_B; pfam02538
382638002271	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
382638002272	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
382638002273	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
382638002274	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
382638002275	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
382638002276	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
382638002277	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
382638002278	putative acyltransferase; Provisional; Region: PRK05790
382638002279	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
382638002280	dimer interface [polypeptide binding]; other site
382638002281	active site
382638002282	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
382638002283	DNA gyrase subunit A; Validated; Region: PRK05560
382638002284	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
382638002285	CAP-like domain; other site
382638002286	active site
382638002287	primary dimer interface [polypeptide binding]; other site
382638002288	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
382638002289	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
382638002290	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
382638002291	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
382638002292	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
382638002293	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
382638002294	Response regulator receiver domain; Region: Response_reg; pfam00072
382638002295	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
382638002296	active site
382638002297	phosphorylation site [posttranslational modification]
382638002298	intermolecular recognition site; other site
382638002299	dimerization interface [polypeptide binding]; other site
382638002300	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638002301	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
382638002302	Walker A motif; other site
382638002303	ATP binding site [chemical binding]; other site
382638002304	Walker B motif; other site
382638002305	arginine finger; other site
382638002306	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
382638002307	cofactor binding site; other site
382638002308	DNA binding site [nucleotide binding]
382638002309	substrate interaction site [chemical binding]; other site
382638002310	GTP-binding protein LepA; Provisional; Region: PRK05433
382638002311	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
382638002312	G1 box; other site
382638002313	putative GEF interaction site [polypeptide binding]; other site
382638002314	GTP/Mg2+ binding site [chemical binding]; other site
382638002315	Switch I region; other site
382638002316	G2 box; other site
382638002317	G3 box; other site
382638002318	Switch II region; other site
382638002319	G4 box; other site
382638002320	G5 box; other site
382638002321	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
382638002322	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
382638002323	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
382638002324	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
382638002325	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
382638002326	TPP-binding site; other site
382638002327	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
382638002328	PYR/PP interface [polypeptide binding]; other site
382638002329	dimer interface [polypeptide binding]; other site
382638002330	TPP binding site [chemical binding]; other site
382638002331	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
382638002332	flagellar assembly protein H; Validated; Region: fliH; PRK06669
382638002333	Flagellar assembly protein FliH; Region: FliH; pfam02108
382638002334	flagellar motor switch protein FliG; Region: fliG; TIGR00207
382638002335	FliG C-terminal domain; Region: FliG_C; pfam01706
382638002336	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
382638002337	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
382638002338	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
382638002339	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
382638002340	CTP synthetase; Validated; Region: pyrG; PRK05380
382638002341	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
382638002342	Catalytic site [active]
382638002343	active site
382638002344	UTP binding site [chemical binding]; other site
382638002345	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
382638002346	active site
382638002347	putative oxyanion hole; other site
382638002348	catalytic triad [active]
382638002349	DHH family; Region: DHH; pfam01368
382638002350	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
382638002351	DHHA1 domain; Region: DHHA1; pfam02272
382638002352	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
382638002353	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
382638002354	active site
382638002355	Protein of unknown function (DUF1294); Region: DUF1294; cl01311
382638002356	Protein of unknown function (DUF1294); Region: DUF1294; cl01311
382638002357	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
382638002358	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
382638002359	TPR motif; other site
382638002360	binding surface
382638002361	Sel1-like repeats; Region: SEL1; smart00671
382638002362	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
382638002363	DNA protecting protein DprA; Region: dprA; TIGR00732
382638002364	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
382638002365	cell division topological specificity factor MinE; Region: minE; TIGR01215
382638002366	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
382638002367	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
382638002368	Switch I; other site
382638002369	Switch II; other site
382638002370	ketol-acid reductoisomerase; Provisional; Region: PRK05479
382638002371	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
382638002372	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
382638002373	NAD synthetase; Provisional; Region: PRK13980
382638002374	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
382638002375	homodimer interface [polypeptide binding]; other site
382638002376	NAD binding pocket [chemical binding]; other site
382638002377	ATP binding pocket [chemical binding]; other site
382638002378	Mg binding site [ion binding]; other site
382638002379	active-site loop [active]
382638002380	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
382638002381	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
382638002382	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
382638002383	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
382638002384	Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: spsG; COG3980
382638002385	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
382638002386	ligand binding site; other site
382638002387	tetramer interface; other site
382638002388	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
382638002389	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
382638002390	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002391	nuclease NucT; Provisional; Region: PRK13912
382638002392	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
382638002393	putative active site [active]
382638002394	catalytic site [active]
382638002395	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
382638002396	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
382638002397	catalytic site [active]
382638002398	G-X2-G-X-G-K; other site
382638002399	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
382638002400	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
382638002401	arginyl-tRNA synthetase; Region: argS; TIGR00456
382638002402	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
382638002403	active site
382638002404	HIGH motif; other site
382638002405	KMSK motif region; other site
382638002406	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
382638002407	tRNA binding surface [nucleotide binding]; other site
382638002408	anticodon binding site; other site
382638002409	heme oxygenase, HugZ family; Region: heme_ox_HugZ; TIGR04109
382638002410	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
382638002411	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
382638002412	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002413	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
382638002414	putative substrate translocation pore; other site
382638002415	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
382638002416	Major Facilitator Superfamily; Region: MFS_1; pfam07690
382638002417	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
382638002418	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
382638002419	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
382638002420	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
382638002421	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638002422	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
382638002423	active site
382638002424	catalytic site [active]
382638002425	Zn binding site [ion binding]; other site
382638002426	tetramer interface [polypeptide binding]; other site
382638002427	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
382638002428	Predicted amidohydrolase [General function prediction only]; Region: COG0388
382638002429	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
382638002430	active site
382638002431	catalytic triad [active]
382638002432	dimer interface [polypeptide binding]; other site
382638002433	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
382638002434	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
382638002435	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
382638002436	inhibitor-cofactor binding pocket; inhibition site
382638002437	pyridoxal 5'-phosphate binding site [chemical binding]; other site
382638002438	catalytic residue [active]
382638002439	Predicted SPOUT methyltransferase; Region: SPOUT_MTase; cl00679
382638002440	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
382638002441	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
382638002442	putative recombination protein RecO; Provisional; Region: PRK13908
382638002443	competence/damage-inducible protein CinA C-terminal domain; Region: cinA_cterm; TIGR00199
382638002444	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
382638002445	dimer interface [polypeptide binding]; other site
382638002446	FMN binding site [chemical binding]; other site
382638002447	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
382638002448	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
382638002449	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
382638002450	active site
382638002451	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
382638002452	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
382638002453	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
382638002454	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
382638002455	Putative zinc ribbon domain; Region: DUF164; pfam02591
382638002456	dinuclear metal center protein, YbgI/SA1388 family; Region: YbgI_SA1388; TIGR00486
382638002457	Uncharacterized conserved protein [Function unknown]; Region: COG0327
382638002458	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
382638002459	dimer interface [polypeptide binding]; other site
382638002460	motif 1; other site
382638002461	active site
382638002462	motif 2; other site
382638002463	motif 3; other site
382638002464	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
382638002465	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
382638002466	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
382638002467	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
382638002468	G3 box; other site
382638002469	Switch II region; other site
382638002470	GTP/Mg2+ binding site [chemical binding]; other site
382638002471	G4 box; other site
382638002472	G5 box; other site
382638002473	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
382638002474	G3 box; other site
382638002475	Switch II region; other site
382638002476	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
382638002477	Dynamin family; Region: Dynamin_N; pfam00350
382638002478	G1 box; other site
382638002479	GTP/Mg2+ binding site [chemical binding]; other site
382638002480	G2 box; other site
382638002481	Switch I region; other site
382638002482	Uncharacterized virulence-associated protein D [Function unknown]; Region: VapD; COG3309
382638002483	Protein of unknown function (DUF3240); Region: DUF3240; pfam11582
382638002484	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
382638002485	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
382638002486	Outer membrane efflux protein; Region: OEP; pfam02321
382638002487	Outer membrane efflux protein; Region: OEP; pfam02321
382638002488	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
382638002489	phosphoglyceromutase; Provisional; Region: PRK05434
382638002490	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
382638002491	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; Region: gatC; TIGR00135
382638002492	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
382638002493	Ferritin-like domain; Region: Ferritin; pfam00210
382638002494	ferroxidase diiron center [ion binding]; other site
382638002495	phosphoserine phosphatase SerB; Region: serB; TIGR00338
382638002496	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
382638002497	motif II; other site
382638002498	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
382638002499	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
382638002500	ligand binding site [chemical binding]; other site
382638002501	active site
382638002502	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
382638002503	Aspartase; Region: Aspartase; cd01357
382638002504	active sites [active]
382638002505	tetramer interface [polypeptide binding]; other site
382638002506	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
382638002507	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
382638002508	hinge; other site
382638002509	active site
382638002510	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
382638002511	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
382638002512	active site
382638002513	tetramer interface; other site
382638002514	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
382638002515	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
382638002516	N-acetyl-D-glucosamine binding site [chemical binding]; other site
382638002517	catalytic residue [active]
382638002518	YGGT family; Region: YGGT; pfam02325
382638002519	glutamylglutaminyl-tRNA synthetase; Provisional; Region: PRK12410
382638002520	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
382638002521	active site
382638002522	HIGH motif; other site
382638002523	nucleotide binding site [chemical binding]; other site
382638002524	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
382638002525	active site
382638002526	KMSKS motif; other site
382638002527	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002528	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
382638002529	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
382638002530	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
382638002531	G1 box; other site
382638002532	putative GEF interaction site [polypeptide binding]; other site
382638002533	GTP/Mg2+ binding site [chemical binding]; other site
382638002534	Switch I region; other site
382638002535	G2 box; other site
382638002536	G3 box; other site
382638002537	Switch II region; other site
382638002538	G4 box; other site
382638002539	G5 box; other site
382638002540	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
382638002541	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
382638002542	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
382638002543	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
382638002544	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
382638002545	6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Region: COG0720
382638002546	formamidase; Provisional; Region: amiF; PRK13287
382638002547	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
382638002548	multimer interface [polypeptide binding]; other site
382638002549	active site
382638002550	catalytic triad [active]
382638002551	dimer interface [polypeptide binding]; other site
382638002552	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
382638002553	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
382638002554	Coenzyme A binding pocket [chemical binding]; other site
382638002555	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
382638002556	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
382638002557	6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Region: COG0720
382638002558	Predicted acid phosphatase [General function prediction only]; Region: SurE; COG0496
382638002559	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
382638002560	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
382638002561	substrate binding pocket [chemical binding]; other site
382638002562	chain length determination region; other site
382638002563	substrate-Mg2+ binding site; other site
382638002564	catalytic residues [active]
382638002565	aspartate-rich region 1; other site
382638002566	active site lid residues [active]
382638002567	aspartate-rich region 2; other site
382638002568	GTP cyclohydrolase I; Region: folE; TIGR00063
382638002569	GTP cyclohydrolase I; Provisional; Region: PLN03044
382638002570	active site
382638002571	heat shock protein HtpX; Provisional; Region: PRK02870
382638002572	tRNA pseudouridine synthase, TruD family; Region: tRNA_TruD_broad; TIGR00094
382638002573	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
382638002574	Permutation of conserved domain; other site
382638002575	active site
382638002576	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
382638002577	recombination protein RecR; Region: recR; TIGR00615
382638002578	RecR protein; Region: RecR; pfam02132
382638002579	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
382638002580	active site
382638002581	metal binding site [ion binding]; metal-binding site
382638002582	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
382638002583	hexamer interface [polypeptide binding]; other site
382638002584	active site 2 [active]
382638002585	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002586	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
382638002587	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
382638002588	active site
382638002589	HIGH motif; other site
382638002590	nucleotide binding site [chemical binding]; other site
382638002591	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
382638002592	active site
382638002593	KMSKS motif; other site
382638002594	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
382638002595	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
382638002596	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002597	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
382638002598	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
382638002599	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
382638002600	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
382638002601	active site
382638002602	Zn binding site [ion binding]; other site
382638002603	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
382638002604	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
382638002605	putative metal binding site [ion binding]; other site
382638002606	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
382638002607	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
382638002608	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
382638002609	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
382638002610	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
382638002611	ATP binding site [chemical binding]; other site
382638002612	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
382638002613	putative Mg++ binding site [ion binding]; other site
382638002614	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
382638002615	Methyltransferase domain; Region: Methyltransf_26; pfam13659
382638002616	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
382638002617	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
382638002618	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
382638002619	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
382638002620	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
382638002621	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
382638002622	putative domain interface [polypeptide binding]; other site
382638002623	putative active site [active]
382638002624	catalytic site [active]
382638002625	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
382638002626	putative active site [active]
382638002627	putative domain interface [polypeptide binding]; other site
382638002628	catalytic site [active]
382638002629	dihydroorotate dehydrogenase, subfamily 2; Region: pyrD_sub2; TIGR01036
382638002630	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
382638002631	quinone interaction residues [chemical binding]; other site
382638002632	active site
382638002633	catalytic residues [active]
382638002634	FMN binding site [chemical binding]; other site
382638002635	substrate binding site [chemical binding]; other site
382638002636	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
382638002637	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
382638002638	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
382638002639	dihydrodipicolinate synthase; Region: dapA; TIGR00674
382638002640	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
382638002641	dimer interface [polypeptide binding]; other site
382638002642	active site
382638002643	catalytic residue [active]
382638002644	7-alpha-hydroxysteroid dehydrogenase; Provisional; Region: PRK08416
382638002645	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
382638002646	putative NAD(P) binding site [chemical binding]; other site
382638002647	active site
382638002648	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Region: pgsA; TIGR00560
382638002649	S-methylmethionine transporter; Provisional; Region: PRK11387
382638002650	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
382638002651	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
382638002652	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
382638002653	protein binding site [polypeptide binding]; other site
382638002654	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
382638002655	protein binding site [polypeptide binding]; other site
382638002656	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
382638002657	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
382638002658	substrate binding site; other site
382638002659	dimer interface; other site
382638002660	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
382638002661	homotrimer interaction site [polypeptide binding]; other site
382638002662	zinc binding site [ion binding]; other site
382638002663	CDP-binding sites; other site
382638002664	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
382638002665	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
382638002666	active site
382638002667	dimerization interface [polypeptide binding]; other site
382638002668	5'-3' exonuclease; Provisional; Region: PRK14976
382638002669	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
382638002670	putative active site [active]
382638002671	Helix-hairpin-helix class 2 (Pol1 family) motifs; Region: HhH2; smart00279
382638002672	DNA binding site [nucleotide binding]
382638002673	metal binding site [ion binding]; metal-binding site
382638002674	chaperone protein DnaJ; Provisional; Region: PRK14299
382638002675	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
382638002676	HSP70 interaction site [polypeptide binding]; other site
382638002677	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
382638002678	substrate binding site [polypeptide binding]; other site
382638002679	dimer interface [polypeptide binding]; other site
382638002680	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
382638002681	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
382638002682	DNA binding residues [nucleotide binding]
382638002683	putative dimer interface [polypeptide binding]; other site
382638002684	ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; Region: MGS1; COG2256
382638002685	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638002686	Walker A motif; other site
382638002687	ATP binding site [chemical binding]; other site
382638002688	Walker B motif; other site
382638002689	arginine finger; other site
382638002690	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
382638002691	ferric uptake regulator; Provisional; Region: fur; PRK09462
382638002692	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
382638002693	metal binding site 2 [ion binding]; metal-binding site
382638002694	putative DNA binding helix; other site
382638002695	metal binding site 1 [ion binding]; metal-binding site
382638002696	dimer interface [polypeptide binding]; other site
382638002697	structural Zn2+ binding site [ion binding]; other site
382638002698	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
382638002699	Domain of unknown function (DUF386); Region: DUF386; cl01047
382638002700	flagellar motor switch protein FliY; Validated; Region: PRK08432
382638002701	flagellar motor switch protein FliN; Region: fliN; TIGR02480
382638002702	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
382638002703	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
382638002704	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
382638002705	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
382638002706	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
382638002707	DNA binding residues [nucleotide binding]
382638002708	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
382638002709	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
382638002710	P-loop; other site
382638002711	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
382638002712	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
382638002713	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
382638002714	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
382638002715	catalytic center binding site [active]
382638002716	ATP binding site [chemical binding]; other site
382638002717	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
382638002718	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
382638002719	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
382638002720	active site
382638002721	Dehydroquinase class II; Region: DHquinase_II; pfam01220
382638002722	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
382638002723	trimer interface [polypeptide binding]; other site
382638002724	active site
382638002725	dimer interface [polypeptide binding]; other site
382638002726	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
382638002727	O-Antigen ligase; Region: Wzy_C; pfam04932
382638002728	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
382638002729	16S/18S rRNA binding site [nucleotide binding]; other site
382638002730	S13e-L30e interaction site [polypeptide binding]; other site
382638002731	25S rRNA binding site [nucleotide binding]; other site
382638002732	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
382638002733	FHIPEP family; Region: FHIPEP; pfam00771
382638002734	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
382638002735	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002736	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
382638002737	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
382638002738	active site
382638002739	intermolecular recognition site; other site
382638002740	dimerization interface [polypeptide binding]; other site
382638002741	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
382638002742	DNA binding site [nucleotide binding]
382638002743	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
382638002744	putative active site [active]
382638002745	putative metal binding site [ion binding]; other site
382638002746	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
382638002747	acetyl-CoA synthetase; Provisional; Region: PRK00174
382638002748	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
382638002749	active site
382638002750	CoA binding site [chemical binding]; other site
382638002751	acyl-activating enzyme (AAE) consensus motif; other site
382638002752	AMP binding site [chemical binding]; other site
382638002753	acetate binding site [chemical binding]; other site
382638002754	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG0779
382638002755	Sm and related proteins; Region: Sm_like; cl00259
382638002756	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
382638002757	putative oligomer interface [polypeptide binding]; other site
382638002758	putative RNA binding site [nucleotide binding]; other site
382638002759	Ribosome-binding factor A; Region: RBFA; cl00542
382638002760	translation initiation factor IF-2; Region: IF-2; TIGR00487
382638002761	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
382638002762	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
382638002763	G1 box; other site
382638002764	putative GEF interaction site [polypeptide binding]; other site
382638002765	GTP/Mg2+ binding site [chemical binding]; other site
382638002766	Switch I region; other site
382638002767	G2 box; other site
382638002768	G3 box; other site
382638002769	Switch II region; other site
382638002770	G4 box; other site
382638002771	G5 box; other site
382638002772	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
382638002773	Translation-initiation factor 2; Region: IF-2; pfam11987
382638002774	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
382638002775	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cl00189
382638002776	homoserine kinase; Region: thrB; TIGR00191
382638002777	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
382638002778	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
382638002779	UDP-3-0-acyl N-acetylglucosamine deacetylase; Region: lpxC; TIGR00325
382638002780	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
382638002781	septum formation inhibitor; Reviewed; Region: minC; PRK00556
382638002782	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
382638002783	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
382638002784	Peptidase family M23; Region: Peptidase_M23; pfam01551
382638002785	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002786	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002787	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
382638002788	oligomerization interface [polypeptide binding]; other site
382638002789	active site
382638002790	metal binding site [ion binding]; metal-binding site
382638002791	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
382638002792	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638002793	Walker A motif; other site
382638002794	ATP binding site [chemical binding]; other site
382638002795	Walker B motif; other site
382638002796	arginine finger; other site
382638002797	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
382638002798	sec-independent translocase; Provisional; Region: PRK04098
382638002799	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
382638002800	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
382638002801	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
382638002802	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
382638002803	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
382638002804	S-adenosylmethionine binding site [chemical binding]; other site
382638002805	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002806	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
382638002807	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
382638002808	active site
382638002809	phosphorylation site [posttranslational modification]
382638002810	intermolecular recognition site; other site
382638002811	dimerization interface [polypeptide binding]; other site
382638002812	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
382638002813	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
382638002814	S-adenosylmethionine binding site [chemical binding]; other site
382638002815	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
382638002816	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
382638002817	Walker A motif; other site
382638002818	ATP binding site [chemical binding]; other site
382638002819	Walker B motif; other site
382638002820	arginine finger; other site
382638002821	Peptidase family M41; Region: Peptidase_M41; pfam01434
382638002822	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
382638002823	CDP-diacylglycerol--serine O-phosphatidyltransferase; Region: pssA; TIGR00473
382638002824	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
382638002825	metal-binding site [ion binding]
382638002826	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
382638002827	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
382638002828	Soluble P-type ATPase [General function prediction only]; Region: COG4087
382638002829	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
382638002830	metal-binding site [ion binding]
382638002831	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cd00596
382638002832	active site
382638002833	Zn binding site [ion binding]; other site
382638002834	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
382638002835	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
382638002836	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
382638002837	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
382638002838	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
382638002839	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
382638002840	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
382638002841	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
382638002842	active site
382638002843	amidohydrolase, AtzE family; Region: amido_AtzE; TIGR02715
382638002844	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
382638002845	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
382638002846	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
382638002847	CoA-binding site [chemical binding]; other site
382638002848	ATP-binding [chemical binding]; other site
382638002849	spermidine synthase; Provisional; Region: speE; PRK00536
382638002850	spermidine synthase; Provisional; Region: PRK00811
382638002851	GTP-binding protein Der; Reviewed; Region: PRK00093
382638002852	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
382638002853	G1 box; other site
382638002854	GTP/Mg2+ binding site [chemical binding]; other site
382638002855	Switch I region; other site
382638002856	G2 box; other site
382638002857	Switch II region; other site
382638002858	G3 box; other site
382638002859	G4 box; other site
382638002860	G5 box; other site
382638002861	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
382638002862	G1 box; other site
382638002863	GTP/Mg2+ binding site [chemical binding]; other site
382638002864	Switch I region; other site
382638002865	G2 box; other site
382638002866	G3 box; other site
382638002867	Switch II region; other site
382638002868	G4 box; other site
382638002869	G5 box; other site
382638002870	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
382638002871	IHF dimer interface [polypeptide binding]; other site
382638002872	IHF - DNA interface [nucleotide binding]; other site
382638002873	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
382638002874	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
382638002875	Long-chain fatty acid transport protein [Lipid metabolism]; Region: FadL; COG2067
382638002876	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
382638002877	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
382638002878	NAD(P) binding site [chemical binding]; other site
382638002879	homodimer interface [polypeptide binding]; other site
382638002880	substrate binding site [chemical binding]; other site
382638002881	active site
382638002882	phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Region: coaBC_dfp; TIGR00521
382638002883	Flavoprotein; Region: Flavoprotein; pfam02441
382638002884	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
382638002885	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
382638002886	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
382638002887	cofactor binding site; other site
382638002888	DNA binding site [nucleotide binding]
382638002889	substrate interaction site [chemical binding]; other site
382638002890	HaeIII restriction endonuclease; Region: RE_HaeIII; pfam09556
382638002891	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
382638002892	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
382638002893	active site
382638002894	Protein of unknown function (DUF511); Region: DUF511; cl01114
382638002895	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
382638002896	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638002897	Walker A/P-loop; other site
382638002898	ATP binding site [chemical binding]; other site
382638002899	Q-loop/lid; other site
382638002900	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
382638002901	ABC transporter; Region: ABC_tran_2; pfam12848
382638002902	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
382638002903	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
382638002904	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
382638002905	active site
382638002906	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
382638002907	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
382638002908	putative ribose interaction site [chemical binding]; other site
382638002909	putative ADP binding site [chemical binding]; other site
382638002910	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
382638002911	active site
382638002912	nucleotide binding site [chemical binding]; other site
382638002913	HIGH motif; other site
382638002914	KMSKS motif; other site
382638002915	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
382638002916	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
382638002917	NAD(P) binding site [chemical binding]; other site
382638002918	active site
382638002919	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
382638002920	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
382638002921	active site
382638002922	motif I; other site
382638002923	motif II; other site
382638002924	Uncharacterized conserved protein [Function unknown]; Region: COG2836
382638002925	pantothenate kinase; Reviewed; Region: PRK13333
382638002926	PQQ-like domain; Region: PQQ_2; pfam13360
382638002927	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
382638002928	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
382638002929	trimer interface [polypeptide binding]; other site
382638002930	active site
382638002931	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
382638002932	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
382638002933	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
382638002934	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
382638002935	lipid-A-disaccharide synthase; Region: lpxB; TIGR00215
382638002936	hydrogenase nickel incorporation protein; Provisional; Region: hypA; PRK00564
382638002937	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
382638002938	flagellar hook protein FlgE; Validated; Region: flgE; PRK08425
382638002939	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
382638002940	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
382638002941	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
382638002942	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
382638002943	CDP-diacylglycerol pyrophosphatase; Region: CDH; cl00934
382638002944	PhnA protein; Region: PhnA; pfam03831
382638002945	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
382638002946	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
382638002947	tetramer interface [polypeptide binding]; other site
382638002948	heme binding pocket [chemical binding]; other site
382638002949	NADPH binding site [chemical binding]; other site
382638002950	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
382638002951	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
382638002952	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
382638002953	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
382638002954	active site
382638002955	putative DNA-binding cleft [nucleotide binding]; other site
382638002956	dimer interface [polypeptide binding]; other site
382638002957	Uncharacterized conserved protein [Function unknown]; Region: COG1432
382638002958	LabA_like proteins; Region: LabA_like; cd06167
382638002959	putative metal binding site [ion binding]; other site
382638002960	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638002961	Holliday junction DNA helicase, RuvA subunit; Region: ruvA; TIGR00084
382638002962	RuvA N terminal domain; Region: RuvA_N; pfam01330
382638002963	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
382638002964	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
382638002965	MviN-like protein; Region: MVIN; pfam03023
382638002966	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
382638002967	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
382638002968	active site
382638002969	HIGH motif; other site
382638002970	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
382638002971	KMSKS motif; other site
382638002972	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
382638002973	tRNA binding surface [nucleotide binding]; other site
382638002974	anticodon binding site; other site
382638002975	Vacuolating cyotoxin; Region: VacA; pfam02691
382638002976	Vacuolating cyotoxin; Region: VacA; pfam02691
382638002977	Vacuolating cyotoxin; Region: VacA; pfam02691
382638002978	Vacuolating cyotoxin; Region: VacA; pfam02691
382638002979	Vacuolating cyotoxin; Region: VacA; pfam02691
382638002980	Vacuolating cyotoxin; Region: VacA; pfam02691
382638002981	Vacuolating cyotoxin; Region: VacA; pfam02691
382638002982	Vacuolating cyotoxin; Region: VacA; pfam02691
382638002983	Vacuolating cyotoxin; Region: VacA; pfam02691
382638002984	Vacuolating cyotoxin; Region: VacA; pfam02691
382638002985	Alpha-2,3-sialyltransferase (CST-I); Region: CST-I; pfam06002
382638002986	Alpha-2,3-sialyltransferase (CST-I); Region: CST-I; pfam06002
382638002987	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
382638002988	ligand binding site; other site
382638002989	tetramer interface; other site
382638002990	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
382638002991	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
382638002992	active site
382638002993	homodimer interface [polypeptide binding]; other site
382638002994	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
382638002995	NeuB family; Region: NeuB; pfam03102
382638002996	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
382638002997	NeuB binding interface [polypeptide binding]; other site
382638002998	putative substrate binding site [chemical binding]; other site
382638002999	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
382638003000	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
382638003001	Walker A/P-loop; other site
382638003002	ATP binding site [chemical binding]; other site
382638003003	Q-loop/lid; other site
382638003004	ABC transporter signature motif; other site
382638003005	Walker B; other site
382638003006	D-loop; other site
382638003007	H-loop/switch region; other site
382638003008	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
382638003009	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
382638003010	ABC-ATPase subunit  interface; other site
382638003011	dimer interface [polypeptide binding]; other site
382638003012	putative PBP binding regions; other site
382638003013	short chain dehydrogenase; Validated; Region: PRK06182
382638003014	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
382638003015	NADP binding site [chemical binding]; other site
382638003016	active site
382638003017	steroid binding site; other site
382638003018	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
382638003019	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003020	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
382638003021	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
382638003022	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypC; COG0298
382638003023	hydrogenase accessory protein HypB; Region: hypB; TIGR00073
382638003024	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
382638003025	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
382638003026	propionate/acetate kinase; Provisional; Region: PRK12379
382638003027	BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; Region: Pta; COG0857
382638003028	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
382638003029	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
382638003030	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK05842
382638003031	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
382638003032	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
382638003033	flagellar hook protein FlgE; Validated; Region: flgE; PRK05841
382638003034	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
382638003035	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
382638003036	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
382638003037	S-adenosylmethionine binding site [chemical binding]; other site
382638003038	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
382638003039	Part of AAA domain; Region: AAA_19; pfam13245
382638003040	Family description; Region: UvrD_C_2; pfam13538
382638003041	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003042	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003043	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
382638003044	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
382638003045	N-terminal plug; other site
382638003046	ligand-binding site [chemical binding]; other site
382638003047	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
382638003048	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
382638003049	dimer interface [polypeptide binding]; other site
382638003050	conserved gate region; other site
382638003051	putative PBP binding loops; other site
382638003052	ABC-ATPase subunit interface; other site
382638003053	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
382638003054	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
382638003055	substrate binding pocket [chemical binding]; other site
382638003056	membrane-bound complex binding site; other site
382638003057	hinge residues; other site
382638003058	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
382638003059	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
382638003060	homotrimer interaction site [polypeptide binding]; other site
382638003061	putative active site [active]
382638003062	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
382638003063	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
382638003064	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
382638003065	amino acid carrier protein; Region: agcS; TIGR00835
382638003066	alanine racemase; Region: alr; TIGR00492
382638003067	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
382638003068	active site
382638003069	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
382638003070	dimer interface [polypeptide binding]; other site
382638003071	substrate binding site [chemical binding]; other site
382638003072	catalytic residues [active]
382638003073	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
382638003074	tRNA (Guanine-1)-methyltransferase; Region: tRNA_m1G_MT; cl00407
382638003075	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK14593
382638003076	RimM N-terminal domain; Region: RimM; pfam01782
382638003077	PRC-barrel domain; Region: PRC; pfam05239
382638003078	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
382638003079	KH domain; Region: KH_4; pfam13083
382638003080	G-X-X-G motif; other site
382638003081	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
382638003082	signal recognition particle protein; Provisional; Region: PRK10867
382638003083	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
382638003084	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
382638003085	P loop; other site
382638003086	GTP binding site [chemical binding]; other site
382638003087	Signal peptide binding domain; Region: SRP_SPB; pfam02978
382638003088	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
382638003089	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
382638003090	active site
382638003091	HIGH motif; other site
382638003092	nucleotide binding site [chemical binding]; other site
382638003093	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
382638003094	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
382638003095	active site
382638003096	KMSKS motif; other site
382638003097	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
382638003098	anticodon binding site; other site
382638003099	flagellar assembly protein FliW; Provisional; Region: PRK13283
382638003100	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
382638003101	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
382638003102	active site
382638003103	homodimer interface [polypeptide binding]; other site
382638003104	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003105	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003106	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
382638003107	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
382638003108	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
382638003109	Fic/DOC family; Region: Fic; pfam02661
382638003110	metal-binding heat shock protein; Provisional; Region: PRK00016
382638003111	flavodoxin FldA; Validated; Region: PRK09267
382638003112	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
382638003113	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
382638003114	Uncharacterized protein, possibly involved in nitrogen fixation [Inorganic ion transport and metabolism]; Region: FixS; COG3197
382638003115	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
382638003116	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
382638003117	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
382638003118	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
382638003119	Predicted helicase [General function prediction only]; Region: COG4889
382638003120	Restriction endonuclease; Region: Mrr_cat_2; pfam13156
382638003121	DEAD-like helicases superfamily; Region: DEXDc; smart00487
382638003122	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
382638003123	ATP binding site [chemical binding]; other site
382638003124	putative Mg++ binding site [ion binding]; other site
382638003125	nucleotide binding region [chemical binding]; other site
382638003126	Helicase conserved C-terminal domain; Region: Helicase_C; pfam00271
382638003127	ATP-binding site [chemical binding]; other site
382638003128	Uncharacterized protein, 4-oxalocrotonate tautomerase homolog [General function prediction only]; Region: COG1942
382638003129	active site 1 [active]
382638003130	dimer interface [polypeptide binding]; other site
382638003131	hexamer interface [polypeptide binding]; other site
382638003132	active site 2 [active]
382638003133	Rad52/22 family double-strand break repair protein; Region: Rad52_Rad22; cl01936
382638003134	Domain of unknown function (DUF932); Region: DUF932; cl12129
382638003135	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
382638003136	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
382638003137	active site
382638003138	dimer interface [polypeptide binding]; other site
382638003139	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
382638003140	dimer interface [polypeptide binding]; other site
382638003141	active site
382638003142	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
382638003143	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638003144	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638003145	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
382638003146	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
382638003147	generic binding surface II; other site
382638003148	generic binding surface I; other site
382638003149	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
382638003150	RIP metalloprotease RseP; Region: TIGR00054
382638003151	active site
382638003152	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
382638003153	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
382638003154	putative substrate binding region [chemical binding]; other site
382638003155	Uncharacterized conserved protein [Function unknown]; Region: COG3334
382638003156	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
382638003157	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
382638003158	GDP-binding site [chemical binding]; other site
382638003159	ACT binding site; other site
382638003160	IMP binding site; other site
382638003161	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003162	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003163	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
382638003164	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
382638003165	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
382638003166	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
382638003167	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
382638003168	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638003169	Q-loop/lid; other site
382638003170	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638003171	Walker B; other site
382638003172	D-loop; other site
382638003173	H-loop/switch region; other site
382638003174	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638003175	Walker A/P-loop; other site
382638003176	ATP binding site [chemical binding]; other site
382638003177	Q-loop/lid; other site
382638003178	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
382638003179	ABC transporter signature motif; other site
382638003180	Walker B; other site
382638003181	D-loop; other site
382638003182	H-loop/switch region; other site
382638003183	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
382638003184	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
382638003185	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
382638003186	SPFH domain / Band 7 family; Region: Band_7; pfam01145
382638003187	helicase 45; Provisional; Region: PTZ00424
382638003188	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
382638003189	ATP binding site [chemical binding]; other site
382638003190	Mg++ binding site [ion binding]; other site
382638003191	motif III; other site
382638003192	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
382638003193	nucleotide binding region [chemical binding]; other site
382638003194	ATP-binding site [chemical binding]; other site
382638003195	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
382638003196	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
382638003197	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
382638003198	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
382638003199	dimer interface [polypeptide binding]; other site
382638003200	phosphorylation site [posttranslational modification]
382638003201	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
382638003202	ATP binding site [chemical binding]; other site
382638003203	Mg2+ binding site [ion binding]; other site
382638003204	G-X-G motif; other site
382638003205	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
382638003206	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
382638003207	dimerization interface [polypeptide binding]; other site
382638003208	DPS ferroxidase diiron center [ion binding]; other site
382638003209	ion pore; other site
382638003210	Domain of unknown function (DUF2018); Region: DUF2018; pfam09442
382638003211	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
382638003212	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
382638003213	substrate binding pocket [chemical binding]; other site
382638003214	chain length determination region; other site
382638003215	substrate-Mg2+ binding site; other site
382638003216	catalytic residues [active]
382638003217	aspartate-rich region 1; other site
382638003218	active site lid residues [active]
382638003219	aspartate-rich region 2; other site
382638003220	glutamyl-tRNA reductase; Region: hemA; TIGR01035
382638003221	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
382638003222	tRNA; other site
382638003223	putative tRNA binding site [nucleotide binding]; other site
382638003224	putative NADP binding site [chemical binding]; other site
382638003225	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
382638003226	prolyl-tRNA synthetase; Provisional; Region: PRK09194
382638003227	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
382638003228	dimer interface [polypeptide binding]; other site
382638003229	motif 1; other site
382638003230	active site
382638003231	motif 2; other site
382638003232	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
382638003233	putative deacylase active site [active]
382638003234	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
382638003235	active site
382638003236	motif 3; other site
382638003237	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
382638003238	anticodon binding site; other site
382638003239	Porphobilinogen deaminase [Coenzyme metabolism]; Region: HemC; COG0181
382638003240	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
382638003241	domain interfaces; other site
382638003242	active site
382638003243	Cytochrome c; Region: Cytochrom_C; cl11414
382638003244	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
382638003245	Sel1-like repeats; Region: SEL1; smart00671
382638003246	Sel1-like repeats; Region: SEL1; smart00671
382638003247	Sel1-like repeats; Region: SEL1; smart00671
382638003248	Sel1-like repeats; Region: SEL1; smart00671
382638003249	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003250	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003251	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638003252	ABC transporter signature motif; other site
382638003253	Walker B; other site
382638003254	D-loop; other site
382638003255	H-loop/switch region; other site
382638003256	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
382638003257	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
382638003258	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
382638003259	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
382638003260	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
382638003261	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
382638003262	Autotransporter beta-domain; Region: Autotransporter; pfam03797
382638003263	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003264	AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873
382638003265	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
382638003266	HlyD family secretion protein; Region: HlyD_3; pfam13437
382638003267	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
382638003268	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
382638003269	substrate binding site [chemical binding]; other site
382638003270	active site
382638003271	3-methyladenine DNA glycosylase; Provisional; Region: PRK13913
382638003272	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
382638003273	minor groove reading motif; other site
382638003274	helix-hairpin-helix signature motif; other site
382638003275	substrate binding pocket [chemical binding]; other site
382638003276	active site
382638003277	flagellin A; Reviewed; Region: PRK12584
382638003278	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
382638003279	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
382638003280	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
382638003281	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
382638003282	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638003283	Walker A/P-loop; other site
382638003284	ATP binding site [chemical binding]; other site
382638003285	ABC transporter; Region: ABC_tran; pfam00005
382638003286	Q-loop/lid; other site
382638003287	ABC transporter signature motif; other site
382638003288	Walker B; other site
382638003289	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638003290	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
382638003291	dimer interface [polypeptide binding]; other site
382638003292	putative CheW interface [polypeptide binding]; other site
382638003293	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
382638003294	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
382638003295	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
382638003296	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
382638003297	catalytic residue [active]
382638003298	Transglycosylase; Region: Transgly; pfam00912
382638003299	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
382638003300	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
382638003301	tumor necrosis factor alpha-inducing protein; Reviewed; Region: PRK12303
382638003302	Disulfide bond formation protein DsbB; Region: DsbB; pfam02600
382638003303	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
382638003304	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638003305	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638003306	Restriction endonuclease [Defense mechanisms]; Region: COG3587
382638003307	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
382638003308	ATP binding site [chemical binding]; other site
382638003309	putative Mg++ binding site [ion binding]; other site
382638003310	2-oxoglutarate-acceptor oxidoreductase subunit OorC; Reviewed; Region: oorC; PRK08441
382638003311	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
382638003312	2-oxoglutarate-acceptor oxidoreductase subunit OorB; Reviewed; Region: oorB; PRK09628
382638003313	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
382638003314	TPP-binding site [chemical binding]; other site
382638003315	2-oxoglutarate-acceptor oxidoreductase subunit OorA; Reviewed; Region: oorA; PRK09627
382638003316	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
382638003317	dimer interface [polypeptide binding]; other site
382638003318	PYR/PP interface [polypeptide binding]; other site
382638003319	TPP binding site [chemical binding]; other site
382638003320	substrate binding site [chemical binding]; other site
382638003321	2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed; Region: oorD; PRK09626
382638003322	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
382638003323	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
382638003324	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
382638003325	dimerization interface [polypeptide binding]; other site
382638003326	Protein of unknown function; Region: DUF3971; pfam13116
382638003327	AsmA-like C-terminal region; Region: AsmA_1; pfam13109
382638003328	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
382638003329	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
382638003330	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
382638003331	minor groove reading motif; other site
382638003332	helix-hairpin-helix signature motif; other site
382638003333	substrate binding pocket [chemical binding]; other site
382638003334	active site
382638003335	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
382638003336	flagellar motor switch protein; Validated; Region: PRK08433
382638003337	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
382638003338	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
382638003339	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
382638003340	active site
382638003341	substrate binding pocket [chemical binding]; other site
382638003342	dimer interface [polypeptide binding]; other site
382638003343	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
382638003344	BNR repeat-like domain; Region: BNR_2; pfam13088
382638003345	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
382638003346	Sulfatase; Region: Sulfatase; pfam00884
382638003347	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14191
382638003348	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
382638003349	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
382638003350	homodimer interface [polypeptide binding]; other site
382638003351	NADP binding site [chemical binding]; other site
382638003352	substrate binding site [chemical binding]; other site
382638003353	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
382638003354	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
382638003355	Catalytic site [active]
382638003356	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
382638003357	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
382638003358	Peptidase family M50; Region: Peptidase_M50; pfam02163
382638003359	active site
382638003360	putative substrate binding region [chemical binding]; other site
382638003361	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
382638003362	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
382638003363	Regulator of replication initiation timing [Replication,    recombination, and repair]; Region: COG4467; cl01853
382638003364	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
382638003365	active site
382638003366	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
382638003367	multifunctional aminopeptidase A; Provisional; Region: PRK00913
382638003368	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
382638003369	interface (dimer of trimers) [polypeptide binding]; other site
382638003370	Substrate-binding/catalytic site; other site
382638003371	Zn-binding sites [ion binding]; other site
382638003372	GTP-binding protein YchF; Reviewed; Region: PRK09601
382638003373	YchF GTPase; Region: YchF; cd01900
382638003374	G1 box; other site
382638003375	GTP/Mg2+ binding site [chemical binding]; other site
382638003376	Switch I region; other site
382638003377	G2 box; other site
382638003378	Switch II region; other site
382638003379	G3 box; other site
382638003380	G4 box; other site
382638003381	G5 box; other site
382638003382	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
382638003383	spiro-SPASM protein; Region: spiroSPASM; TIGR04321
382638003384	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
382638003385	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
382638003386	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
382638003387	N-terminal plug; other site
382638003388	ligand-binding site [chemical binding]; other site
382638003389	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
382638003390	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003391	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
382638003392	23S rRNA binding site [nucleotide binding]; other site
382638003393	L21 binding site [polypeptide binding]; other site
382638003394	L13 binding site [polypeptide binding]; other site
382638003395	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
382638003396	translation initiation factor IF-3; Region: infC; TIGR00168
382638003397	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
382638003398	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
382638003399	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
382638003400	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
382638003401	active site
382638003402	dimer interface [polypeptide binding]; other site
382638003403	motif 1; other site
382638003404	motif 2; other site
382638003405	motif 3; other site
382638003406	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
382638003407	anticodon binding site; other site
382638003408	phosphoenolpyruvate synthase; Validated; Region: PRK06464
382638003409	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
382638003410	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
382638003411	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
382638003412	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003413	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
382638003414	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
382638003415	metal-binding site
382638003416	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
382638003417	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
382638003418	dimerization interface [polypeptide binding]; other site
382638003419	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
382638003420	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
382638003421	dimer interface [polypeptide binding]; other site
382638003422	putative CheW interface [polypeptide binding]; other site
382638003423	S-ribosylhomocysteinase; Provisional; Region: PRK02260
382638003424	cystathionine gamma-synthase/cystathionine beta-lyase; Validated; Region: PRK06176
382638003425	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
382638003426	homodimer interface [polypeptide binding]; other site
382638003427	substrate-cofactor binding pocket; other site
382638003428	pyridoxal 5'-phosphate binding site [chemical binding]; other site
382638003429	catalytic residue [active]
382638003430	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
382638003431	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
382638003432	dimer interface [polypeptide binding]; other site
382638003433	pyridoxal 5'-phosphate binding site [chemical binding]; other site
382638003434	catalytic residue [active]
382638003435	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
382638003436	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
382638003437	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
382638003438	nucleotide binding site [chemical binding]; other site
382638003439	NEF interaction site [polypeptide binding]; other site
382638003440	SBD interface [polypeptide binding]; other site
382638003441	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
382638003442	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
382638003443	dimer interface [polypeptide binding]; other site
382638003444	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
382638003445	heat-inducible transcription repressor; Provisional; Region: PRK03911
382638003446	hypothetical protein; Provisional; Region: PRK05834
382638003447	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
382638003448	flagellin B; Provisional; Region: PRK13588
382638003449	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
382638003450	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
382638003451	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
382638003452	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
382638003453	DNA topoisomerase I; Validated; Region: PRK05582
382638003454	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
382638003455	active site
382638003456	interdomain interaction site; other site
382638003457	putative metal-binding site [ion binding]; other site
382638003458	nucleotide binding site [chemical binding]; other site
382638003459	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
382638003460	domain I; other site
382638003461	DNA binding groove [nucleotide binding]
382638003462	phosphate binding site [ion binding]; other site
382638003463	domain II; other site
382638003464	domain III; other site
382638003465	nucleotide binding site [chemical binding]; other site
382638003466	catalytic site [active]
382638003467	domain IV; other site
382638003468	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
382638003469	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
382638003470	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
382638003471	Fe-S oxidoreductases [Energy production and conversion]; Region: COG0731
382638003472	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
382638003473	FeS/SAM binding site; other site
382638003474	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases and ATP sulphurylases. The domain forms a apha/beta/apha fold which  binds to Adenosine group; Region: Alpha_ANH_like; cd01986
382638003475	Ligand Binding Site [chemical binding]; other site
382638003476	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
382638003477	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
382638003478	dimer interface [polypeptide binding]; other site
382638003479	putative CheW interface [polypeptide binding]; other site
382638003480	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
382638003481	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
382638003482	pyridoxal 5'-phosphate binding site [chemical binding]; other site
382638003483	catalytic residue [active]
382638003484	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
382638003485	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
382638003486	putative ligand binding site [chemical binding]; other site
382638003487	putative NAD binding site [chemical binding]; other site
382638003488	catalytic site [active]
382638003489	Transposase IS200 like; Region: Y1_Tnp; pfam01797
382638003490	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003491	Predicted permeases [General function prediction only]; Region: COG0730
382638003492	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
382638003493	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
382638003494	SelR domain; Region: SelR; pfam01641
382638003495	DNA repair protein RadA; Region: sms; TIGR00416
382638003496	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
382638003497	Walker A motif/ATP binding site; other site
382638003498	ATP binding site [chemical binding]; other site
382638003499	Walker B motif; other site
382638003500	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
382638003501	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
382638003502	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
382638003503	trimerization site [polypeptide binding]; other site
382638003504	active site
382638003505	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
382638003506	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
382638003507	cysteine desulfurase, NifS family, epsilon proteobacteria type; Region: nifS_epsilon; TIGR03403
382638003508	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
382638003509	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
382638003510	catalytic residue [active]
382638003511	Helix-turn-helix domain; Region: HTH_28; pfam13518
382638003512	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
382638003513	substrate binding site [chemical binding]; other site
382638003514	Beta-1,4-N-acetylgalactosaminyltransferase (CgtA); Region: CgtA; pfam06306
382638003515	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
382638003516	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
382638003517	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
382638003518	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
382638003519	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
382638003520	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
382638003521	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
382638003522	transmembrane helices; other site
382638003523	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
382638003524	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
382638003525	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
382638003526	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
382638003527	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
382638003528	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
382638003529	metal binding site [ion binding]; metal-binding site
382638003530	dimer interface [polypeptide binding]; other site
382638003531	heat shock protein 90; Provisional; Region: PRK05218
382638003532	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
382638003533	ATP binding site [chemical binding]; other site
382638003534	Mg2+ binding site [ion binding]; other site
382638003535	G-X-G motif; other site
382638003536	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
382638003537	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
382638003538	Methyltransferase domain; Region: Methyltransf_26; pfam13659
382638003539	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638003540	Protein of unknown function (DUF511); Region: DUF511; pfam04373
382638003541	Protein of unknown function (DUF511); Region: DUF511; cl01114
382638003542	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
382638003543	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
382638003544	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
382638003545	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
382638003546	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
382638003547	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
382638003548	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
382638003549	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
382638003550	DNA binding residues [nucleotide binding]
382638003551	NLPC_P60 stabilising domain, N term; Region: N_NLPC_P60; pfam12912
382638003552	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
382638003553	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
382638003554	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
382638003555	NlpC/P60 family; Region: NLPC_P60; pfam00877
382638003556	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
382638003557	Predicted dehydrogenase [General function prediction only]; Region: COG0579
382638003558	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
382638003559	23S rRNA interface [nucleotide binding]; other site
382638003560	L3 interface [polypeptide binding]; other site
382638003561	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
382638003562	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
382638003563	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
382638003564	dimer interface [polypeptide binding]; other site
382638003565	putative CheW interface [polypeptide binding]; other site
382638003566	peptide chain release factor 1; Validated; Region: prfA; PRK00591
382638003567	This domain is found in peptide chain release factors; Region: PCRF; smart00937
382638003568	RF-1 domain; Region: RF-1; pfam00472
382638003569	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
382638003570	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14324
382638003571	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
382638003572	active site
382638003573	substrate binding site [chemical binding]; other site
382638003574	metal binding site [ion binding]; metal-binding site
382638003575	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
382638003576	urease subunit alpha; Provisional; Region: PRK13986
382638003577	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
382638003578	alpha-gamma subunit interface [polypeptide binding]; other site
382638003579	beta-gamma subunit interface [polypeptide binding]; other site
382638003580	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
382638003581	gamma-beta subunit interface [polypeptide binding]; other site
382638003582	alpha-beta subunit interface [polypeptide binding]; other site
382638003583	urease subunit beta; Provisional; Region: ureB; PRK13985
382638003584	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
382638003585	subunit interactions [polypeptide binding]; other site
382638003586	active site
382638003587	flap region; other site
382638003588	AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293
382638003589	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
382638003590	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
382638003591	dimer interface [polypeptide binding]; other site
382638003592	catalytic residues [active]
382638003593	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
382638003594	UreF; Region: UreF; pfam01730
382638003595	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
382638003596	G1 box; other site
382638003597	GTP/Mg2+ binding site [chemical binding]; other site
382638003598	G2 box; other site
382638003599	Switch I region; other site
382638003600	G3 box; other site
382638003601	Switch II region; other site
382638003602	G4 box; other site
382638003603	G5 box; other site
382638003604	Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829
382638003605	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
382638003606	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
382638003607	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
382638003608	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
382638003609	Ligand binding site; other site
382638003610	metal-binding site
382638003611	DNase/tRNase domain of colicin-like bacteriocin; Region: Colicin-DNase; cl15861
382638003612	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
382638003613	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
382638003614	Probable transposase; Region: OrfB_IS605; pfam01385
382638003615	Transposase IS200 like; Region: Y1_Tnp; cl00848
382638003616	Proline dehydrogenase; Region: Pro_dh; pfam01619
382638003617	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
382638003618	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
382638003619	Glutamate binding site [chemical binding]; other site
382638003620	NAD binding site [chemical binding]; other site
382638003621	catalytic residues [active]
382638003622	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
382638003623	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
382638003624	Na binding site [ion binding]; other site
382638003625	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
382638003626	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
382638003627	Ligand binding site; other site
382638003628	metal-binding site
382638003629	antiporter inner membrane protein; Provisional; Region: PRK11670
382638003630	Domain of unknown function DUF59; Region: DUF59; pfam01883
382638003631	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
382638003632	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638003633	AAA domain; Region: AAA_21; pfam13304
382638003634	Walker A/P-loop; other site
382638003635	ATP binding site [chemical binding]; other site
382638003636	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638003637	Walker B; other site
382638003638	D-loop; other site
382638003639	H-loop/switch region; other site
382638003640	aspartate-semialdehyde dehydrogenase (peptidoglycan organisms); Region: asd_B; TIGR01296
382638003641	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
382638003642	Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: HisS; COG0124
382638003643	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
382638003644	dimer interface [polypeptide binding]; other site
382638003645	motif 1; other site
382638003646	active site
382638003647	motif 2; other site
382638003648	motif 3; other site
382638003649	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
382638003650	anticodon binding site; other site
382638003651	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
382638003652	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
382638003653	putative active site [active]
382638003654	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
382638003655	catalytic tetrad [active]
382638003656	Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Region: Tas; COG0667
382638003657	Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Region: Tas; COG0667
382638003658	elongation factor G; Reviewed; Region: PRK00007
382638003659	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
382638003660	G1 box; other site
382638003661	putative GEF interaction site [polypeptide binding]; other site
382638003662	GTP/Mg2+ binding site [chemical binding]; other site
382638003663	Switch I region; other site
382638003664	G2 box; other site
382638003665	G3 box; other site
382638003666	Switch II region; other site
382638003667	G4 box; other site
382638003668	G5 box; other site
382638003669	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
382638003670	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
382638003671	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
382638003672	30S ribosomal protein S7; Validated; Region: PRK05302
382638003673	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
382638003674	S17 interaction site [polypeptide binding]; other site
382638003675	S8 interaction site; other site
382638003676	16S rRNA interaction site [nucleotide binding]; other site
382638003677	streptomycin interaction site [chemical binding]; other site
382638003678	23S rRNA interaction site [nucleotide binding]; other site
382638003679	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
382638003680	bifunctional DNA-directed RNA polymerase subunit beta/beta'; Reviewed; Region: PRK09603
382638003681	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
382638003682	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
382638003683	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
382638003684	RPB11 interaction site [polypeptide binding]; other site
382638003685	RPB12 interaction site [polypeptide binding]; other site
382638003686	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
382638003687	RPB3 interaction site [polypeptide binding]; other site
382638003688	RPB1 interaction site [polypeptide binding]; other site
382638003689	RPB11 interaction site [polypeptide binding]; other site
382638003690	RPB10 interaction site [polypeptide binding]; other site
382638003691	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
382638003692	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
382638003693	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
382638003694	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
382638003695	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
382638003696	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
382638003697	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
382638003698	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
382638003699	DNA binding site [nucleotide binding]
382638003700	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
382638003701	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
382638003702	core dimer interface [polypeptide binding]; other site
382638003703	peripheral dimer interface [polypeptide binding]; other site
382638003704	L10 interface [polypeptide binding]; other site
382638003705	L11 interface [polypeptide binding]; other site
382638003706	putative EF-Tu interaction site [polypeptide binding]; other site
382638003707	putative EF-G interaction site [polypeptide binding]; other site
382638003708	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
382638003709	23S rRNA interface [nucleotide binding]; other site
382638003710	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
382638003711	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
382638003712	mRNA/rRNA interface [nucleotide binding]; other site
382638003713	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
382638003714	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
382638003715	23S rRNA interface [nucleotide binding]; other site
382638003716	L7/L12 interface [polypeptide binding]; other site
382638003717	putative thiostrepton binding site; other site
382638003718	L25 interface [polypeptide binding]; other site
382638003719	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
382638003720	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
382638003721	putative homodimer interface [polypeptide binding]; other site
382638003722	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
382638003723	heterodimer interface [polypeptide binding]; other site
382638003724	homodimer interface [polypeptide binding]; other site
382638003725	tRNA-specific 2-thiouridylase MnmA; Reviewed; Region: mnmA; PRK00143
382638003726	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
382638003727	elongation factor Tu; Reviewed; Region: PRK00049
382638003728	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
382638003729	G1 box; other site
382638003730	GEF interaction site [polypeptide binding]; other site
382638003731	GTP/Mg2+ binding site [chemical binding]; other site
382638003732	Switch I region; other site
382638003733	G2 box; other site
382638003734	G3 box; other site
382638003735	Switch II region; other site
382638003736	G4 box; other site
382638003737	G5 box; other site
382638003738	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
382638003739	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
382638003740	Antibiotic Binding Site [chemical binding]; other site
382638003741	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
382638003742	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638003743	Walker A/P-loop; other site
382638003744	ATP binding site [chemical binding]; other site
382638003745	Q-loop/lid; other site
382638003746	ABC transporter signature motif; other site
382638003747	Walker B; other site
382638003748	D-loop; other site
382638003749	H-loop/switch region; other site
382638003750	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
382638003751	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
382638003752	F0F1 ATP synthase subunit C; Validated; Region: PRK08482
382638003753	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
382638003754	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
382638003755	oligomer interface [polypeptide binding]; other site
382638003756	RNA binding site [nucleotide binding]; other site
382638003757	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
382638003758	oligomer interface [polypeptide binding]; other site
382638003759	RNA binding site [nucleotide binding]; other site
382638003760	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
382638003761	putative nucleic acid binding region [nucleotide binding]; other site
382638003762	G-X-X-G motif; other site
382638003763	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
382638003764	RNA binding site [nucleotide binding]; other site
382638003765	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG1926
382638003766	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
382638003767	Organic solvent tolerance protein; Region: OstA_C; pfam04453
382638003768	Predicted membrane protein/domain [Function unknown]; Region: COG1714
382638003769	phosphoribosylamine--glycine ligase; Region: purD; TIGR00877
382638003770	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
382638003771	ATP-grasp domain; Region: ATP-grasp_4; cl17255
382638003772	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
382638003773	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
382638003774	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
382638003775	Walker A/P-loop; other site
382638003776	ATP binding site [chemical binding]; other site
382638003777	Q-loop/lid; other site
382638003778	ABC transporter signature motif; other site
382638003779	Walker B; other site
382638003780	D-loop; other site
382638003781	H-loop/switch region; other site
382638003782	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14833
382638003783	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
382638003784	catalytic residue [active]
382638003785	putative FPP diphosphate  binding site; other site
382638003786	putative FPP binding hydrophobic cleft; other site
382638003787	dimer interface [polypeptide binding]; other site
382638003788	putative IPP diphosphate binding site; other site
382638003789	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
382638003790	FAD binding domain; Region: FAD_binding_4; pfam01565
382638003791	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
382638003792	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
382638003793	active site residue [active]
382638003794	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
382638003795	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
382638003796	active site
382638003797	camphor resistance protein CrcB; Provisional; Region: PRK14204
382638003798	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
382638003799	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
382638003800	active site
382638003801	DNA binding site [nucleotide binding]
382638003802	Int/Topo IB signature motif; other site
382638003803	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
382638003804	putative DNA binding site [nucleotide binding]; other site
382638003805	putative Zn2+ binding site [ion binding]; other site
382638003806	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
382638003807	putative DNA binding site [nucleotide binding]; other site
382638003808	putative Zn2+ binding site [ion binding]; other site
382638003809	KaiC; Region: KaiC; pfam06745
382638003810	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
382638003811	Walker A motif; other site
382638003812	ATP binding site [chemical binding]; other site
382638003813	Walker B motif; other site
382638003814	CHC2 zinc finger; Region: zf-CHC2; pfam01807
382638003815	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
382638003816	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
382638003817	active site
382638003818	metal binding site [ion binding]; metal-binding site
382638003819	interdomain interaction site; other site
382638003820	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
382638003821	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
382638003822	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
382638003823	Predicted ATP-dependent Lon-type protease [Posttranslational modification, protein turnover, chaperones]; Region: COG4930
382638003824	Protein of unknown function (DUF4043); Region: DUF4043; pfam13252
382638003825	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
382638003826	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
382638003827	DEAD-like helicases superfamily; Region: DEXDc; smart00487
382638003828	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
382638003829	Carbamoylphosphate synthase small subunit [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarA; COG0505
382638003830	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
382638003831	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
382638003832	catalytic site [active]
382638003833	subunit interface [polypeptide binding]; other site
382638003834	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2952
382638003835	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
382638003836	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
382638003837	EamA-like transporter family; Region: EamA; pfam00892
382638003838	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
382638003839	dihydropteroate synthase; Region: DHPS; TIGR01496
382638003840	substrate binding pocket [chemical binding]; other site
382638003841	dimer interface [polypeptide binding]; other site
382638003842	inhibitor binding site; inhibition site
382638003843	DNA polymerase III subunit delta'; Validated; Region: PRK08485
382638003844	DNA replication regulator; Region: HobA; pfam12163
382638003845	aspartate kinase; Reviewed; Region: PRK06635
382638003846	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
382638003847	putative nucleotide binding site [chemical binding]; other site
382638003848	putative catalytic residues [active]
382638003849	putative Mg ion binding site [ion binding]; other site
382638003850	putative aspartate binding site [chemical binding]; other site
382638003851	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
382638003852	putative allosteric regulatory site; other site
382638003853	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
382638003854	putative allosteric regulatory residue; other site
382638003855	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
382638003856	putative active site [active]
382638003857	Ap4A binding site [chemical binding]; other site
382638003858	nudix motif; other site
382638003859	putative metal binding site [ion binding]; other site
382638003860	Cytochrome c553 [Energy production and conversion]; Region: COG2863
382638003861	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
382638003862	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
382638003863	FeS/SAM binding site; other site
382638003864	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
382638003865	HlyD family secretion protein; Region: HlyD_3; pfam13437
382638003866	Outer membrane efflux protein; Region: OEP; pfam02321
382638003867	YtkA-like; Region: YtkA; pfam13115
382638003868	formyltetrahydrofolate deformylase; Region: PurU; TIGR00655
382638003869	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
382638003870	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
382638003871	active site
382638003872	substrate binding site [chemical binding]; other site
382638003873	cosubstrate binding site; other site
382638003874	catalytic site [active]
382638003875	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
382638003876	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
382638003877	tandem repeat interface [polypeptide binding]; other site
382638003878	oligomer interface [polypeptide binding]; other site
382638003879	active site residues [active]
382638003880	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
382638003881	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
382638003882	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
382638003883	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK03907
382638003884	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
382638003885	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
382638003886	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
382638003887	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
382638003888	Cell cycle protein; Region: FTSW_RODA_SPOVE; pfam01098
382638003889	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
382638003890	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
382638003891	putative ligand binding site [chemical binding]; other site
382638003892	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
382638003893	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
382638003894	dimer interface [polypeptide binding]; other site
382638003895	decamer (pentamer of dimers) interface [polypeptide binding]; other site
382638003896	catalytic triad [active]
382638003897	peroxidatic and resolving cysteines [active]
382638003898	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
382638003899	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
382638003900	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
382638003901	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
382638003902	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
382638003903	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
382638003904	G1 box; other site
382638003905	GTP/Mg2+ binding site [chemical binding]; other site
382638003906	Switch I region; other site
382638003907	G2 box; other site
382638003908	G3 box; other site
382638003909	Switch II region; other site
382638003910	G4 box; other site
382638003911	G5 box; other site
382638003912	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
382638003913	OstA-like protein; Region: OstA; pfam03968
382638003914	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
382638003915	motif II; other site
382638003916	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
382638003917	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
382638003918	Sporulation related domain; Region: SPOR; pfam05036
382638003919	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
382638003920	N-acetyl-D-glucosamine binding site [chemical binding]; other site
382638003921	catalytic residue [active]
382638003922	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
382638003923	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
382638003924	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
382638003925	active site
382638003926	riboflavin synthase, alpha subunit; Region: ribE; TIGR00187
382638003927	Lumazine binding domain; Region: Lum_binding; pfam00677
382638003928	Lumazine binding domain; Region: Lum_binding; pfam00677
382638003929	flhB C-terminus-related protein; Region: flhB_rel; TIGR00789
382638003930	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
382638003931	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
382638003932	Walker A/P-loop; other site
382638003933	ATP binding site [chemical binding]; other site
382638003934	Q-loop/lid; other site
382638003935	ABC transporter signature motif; other site
382638003936	Walker B; other site
382638003937	D-loop; other site
382638003938	H-loop/switch region; other site
382638003939	NIL domain; Region: NIL; pfam09383
382638003940	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
382638003941	lipid A phosphoethanolamine transferase; Reviewed; Region: PRK09598
382638003942	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
382638003943	Sulfatase; Region: Sulfatase; pfam00884
382638003944	lipid A 1-phosphatase; Reviewed; Region: PRK09597
382638003945	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
382638003946	active site
382638003947	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
382638003948	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
382638003949	dimer interface [polypeptide binding]; other site
382638003950	active site
382638003951	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
382638003952	catalytic residues [active]
382638003953	substrate binding site [chemical binding]; other site
382638003954	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
382638003955	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
382638003956	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
382638003957	active site
382638003958	phosphorylation site [posttranslational modification]
382638003959	intermolecular recognition site; other site
382638003960	dimerization interface [polypeptide binding]; other site
382638003961	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
382638003962	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
382638003963	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
382638003964	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
382638003965	Walker A motif; other site
382638003966	ATP binding site [chemical binding]; other site
382638003967	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
382638003968	TrbC/VIRB2 family; Region: TrbC; cl01583
382638003969	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
382638003970	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
382638003971	Ligand Binding Site [chemical binding]; other site
382638003972	DNA primase, catalytic core; Region: dnaG; TIGR01391
382638003973	CHC2 zinc finger; Region: zf-CHC2; pfam01807
382638003974	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
382638003975	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
382638003976	active site
382638003977	metal binding site [ion binding]; metal-binding site
382638003978	interdomain interaction site; other site
382638003979	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
382638003980	oligomerisation interface [polypeptide binding]; other site
382638003981	mobile loop; other site
382638003982	roof hairpin; other site
382638003983	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
382638003984	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
382638003985	ring oligomerisation interface [polypeptide binding]; other site
382638003986	ATP/Mg binding site [chemical binding]; other site
382638003987	stacking interactions; other site
382638003988	hinge regions; other site
382638003989	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638003990	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
382638003991	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
382638003992	P-loop; other site
382638003993	Magnesium ion binding site [ion binding]; other site
382638003994	Protein of unknown function DUF45; Region: DUF45; pfam01863
382638003995	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
382638003996	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
382638003997	homodimer interface [polypeptide binding]; other site
382638003998	substrate-cofactor binding pocket; other site
382638003999	catalytic residue [active]
382638004000	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638004001	DNA polymerase I; Region: pola; TIGR00593
382638004002	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
382638004003	active site
382638004004	metal binding site 1 [ion binding]; metal-binding site
382638004005	putative 5' ssDNA interaction site; other site
382638004006	metal binding site 3; metal-binding site
382638004007	metal binding site 2 [ion binding]; metal-binding site
382638004008	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
382638004009	putative DNA binding site [nucleotide binding]; other site
382638004010	putative metal binding site [ion binding]; other site
382638004011	3'-5' exonuclease; Region: 35EXOc; smart00474
382638004012	active site
382638004013	substrate binding site [chemical binding]; other site
382638004014	catalytic site [active]
382638004015	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
382638004016	active site
382638004017	DNA binding site [nucleotide binding]
382638004018	catalytic site [active]
382638004019	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3421
382638004020	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
382638004021	ATP binding site [chemical binding]; other site
382638004022	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
382638004023	putative Mg++ binding site [ion binding]; other site
382638004024	Type III restriction/modification enzyme methylation subunit; Region: TypeIII_RM_meth; pfam12564
382638004025	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
382638004026	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638004027	DNA methylase; Region: N6_N4_Mtase; pfam01555
382638004028	Heat shock protein [Posttranslational modification, protein turnover, chaperones]; Region: HslJ; COG3187
382638004029	Protein of unknown function (DUF330); Region: DUF330; cl01135
382638004030	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
382638004031	mce related protein; Region: MCE; pfam02470
382638004032	Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cl02488
382638004033	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
382638004034	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
382638004035	Walker A/P-loop; other site
382638004036	ATP binding site [chemical binding]; other site
382638004037	Q-loop/lid; other site
382638004038	ABC transporter signature motif; other site
382638004039	Walker B; other site
382638004040	D-loop; other site
382638004041	H-loop/switch region; other site
382638004042	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
382638004043	conserved hypothetical integral membrane protein; Region: TIGR00056
382638004044	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638004045	YihY family inner membrane protein; Region: yihY_not_rbn; TIGR00765
382638004046	biotin synthase; Provisional; Region: PRK08508
382638004047	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
382638004048	FeS/SAM binding site; other site
382638004049	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
382638004050	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
382638004051	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
382638004052	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
382638004053	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
382638004054	thymidylate kinase; Validated; Region: tmk; PRK00698
382638004055	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
382638004056	TMP-binding site; other site
382638004057	ATP-binding site [chemical binding]; other site
382638004058	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
382638004059	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
382638004060	active site
382638004061	(T/H)XGH motif; other site
382638004062	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
382638004063	Flavoprotein; Region: Flavoprotein; pfam02441
382638004064	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK08515
382638004065	flagella basal body P-ring formation protein FlgA; Region: flgA_cterm; TIGR03170
382638004066	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
382638004067	Part of AAA domain; Region: AAA_19; pfam13245
382638004068	Family description; Region: UvrD_C_2; pfam13538
382638004069	Tetratricopeptide repeat; Region: TPR_16; pfam13432
382638004070	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
382638004071	binding surface
382638004072	TPR motif; other site
382638004073	seryl-tRNA synthetase; Provisional; Region: PRK05431
382638004074	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
382638004075	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
382638004076	dimer interface [polypeptide binding]; other site
382638004077	active site
382638004078	motif 1; other site
382638004079	motif 2; other site
382638004080	motif 3; other site
382638004081	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
382638004082	Predicted amidohydrolase [General function prediction only]; Region: COG0388
382638004083	active site
382638004084	catalytic triad [active]
382638004085	dimer interface [polypeptide binding]; other site
382638004086	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK14065
382638004087	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
382638004088	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
382638004089	S-adenosylmethionine binding site [chemical binding]; other site
382638004090	Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863
382638004091	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
382638004092	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
382638004093	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
382638004094	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
382638004095	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
382638004096	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
382638004097	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
382638004098	HlyD family secretion protein; Region: HlyD_3; pfam13437
382638004099	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
382638004100	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
382638004101	Domain of unknown function DUF21; Region: DUF21; pfam01595
382638004102	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
382638004103	Transporter associated domain; Region: CorC_HlyC; smart01091
382638004104	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
382638004105	Phosphate transporter family; Region: PHO4; pfam01384
382638004106	Phosphate transporter family; Region: PHO4; cl00396
382638004107	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
382638004108	UDP-N-acetylmuramyl-tripeptide synthetase; Region: murE; TIGR01085
382638004109	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
382638004110	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
382638004111	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
382638004112	putative active site [active]
382638004113	transaldolase; Provisional; Region: PRK03903
382638004114	catalytic residue [active]
382638004115	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
382638004116	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
382638004117	5S rRNA interface [nucleotide binding]; other site
382638004118	CTC domain interface [polypeptide binding]; other site
382638004119	L16 interface [polypeptide binding]; other site
382638004120	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
382638004121	putative active site [active]
382638004122	catalytic residue [active]
382638004123	Predicted permeases [General function prediction only]; Region: COG0795
382638004124	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
382638004125	Arginase family; Region: Arginase; cd09989
382638004126	active site
382638004127	Mn binding site [ion binding]; other site
382638004128	oligomer interface [polypeptide binding]; other site
382638004129	Amino acid transporters [Amino acid transport and metabolism]; Region: LysP; COG0833
382638004130	Amino acid transporters [Amino acid transport and metabolism]; Region: LysP; COG0833
382638004131	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
382638004132	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
382638004133	hexamer interface [polypeptide binding]; other site
382638004134	ligand binding site [chemical binding]; other site
382638004135	putative active site [active]
382638004136	NAD(P) binding site [chemical binding]; other site
382638004137	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
382638004138	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
382638004139	ATP-NAD kinase; Region: NAD_kinase; pfam01513
382638004140	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
382638004141	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
382638004142	Walker A/P-loop; other site
382638004143	ATP binding site [chemical binding]; other site
382638004144	Q-loop/lid; other site
382638004145	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
382638004146	ABC transporter signature motif; other site
382638004147	Walker B; other site
382638004148	D-loop; other site
382638004149	H-loop/switch region; other site
382638004150	Domain of unknown function (DUF814); Region: DUF814; pfam05670
382638004151	DNA polymerase III subunit epsilon; Provisional; Region: PRK08517
382638004152	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
382638004153	active site
382638004154	catalytic site [active]
382638004155	substrate binding site [chemical binding]; other site
382638004156	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
382638004157	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
382638004158	substrate binding site [chemical binding]; other site
382638004159	hexamer interface [polypeptide binding]; other site
382638004160	metal binding site [ion binding]; metal-binding site
382638004161	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
382638004162	active site
382638004163	Methyltransferase domain; Region: Methyltransf_26; pfam13659
382638004164	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
382638004165	Biotin and Thiamin Synthesis associated domain; Region: BATS; cl06149
382638004166	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
382638004167	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
382638004168	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
382638004169	glutaminase active site [active]
382638004170	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
382638004171	dimer interface [polypeptide binding]; other site
382638004172	active site
382638004173	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
382638004174	dimer interface [polypeptide binding]; other site
382638004175	active site
382638004176	Protein of unknown function (DUF2443); Region: DUF2443; pfam10398
382638004177	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
382638004178	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
382638004179	Initiator Replication protein; Region: Rep_3; pfam01051