-- dump date   	20140619_112439
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
679897000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
679897000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
679897000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897000004	Walker A motif; other site
679897000005	ATP binding site [chemical binding]; other site
679897000006	Walker B motif; other site
679897000007	arginine finger; other site
679897000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
679897000009	DnaA box-binding interface [nucleotide binding]; other site
679897000010	HMMPfam hit to PF00308, Bac_DnaA, score 9.9e-100
679897000011	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000012	HMMPfam hit to PF08299, Bac_DnaA_C, score 1.1e-18
679897000013	DNA polymerase III subunit beta; Validated; Region: PRK05643
679897000014	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
679897000015	putative DNA binding surface [nucleotide binding]; other site
679897000016	dimer interface [polypeptide binding]; other site
679897000017	beta-clamp/clamp loader binding surface; other site
679897000018	beta-clamp/translesion DNA polymerase binding surface; other site
679897000019	HMMPfam hit to PF00712, DNA_pol3_beta, score 1.3e-19
679897000020	HMMPfam hit to PF02767, DNA_pol3_beta_2, score 8.8e-17
679897000021	HMMPfam hit to PF02768, DNA_pol3_beta_3, score 0.00098
679897000022	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
679897000023	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
679897000024	Mg2+ binding site [ion binding]; other site
679897000025	G-X-G motif; other site
679897000026	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
679897000027	anchoring element; other site
679897000028	dimer interface [polypeptide binding]; other site
679897000029	ATP binding site [chemical binding]; other site
679897000030	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
679897000031	active site
679897000032	putative metal-binding site [ion binding]; other site
679897000033	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
679897000034	HMMPfam hit to PF02518, HATPase_c, score 3.4e-27
679897000035	HMMPfam hit to PF00204, DNA_gyraseB, score 1.1e-78
679897000036	HMMPfam hit to PF01751, Toprim, score 9.3e-10
679897000037	PS00177 DNA topoisomerase II signature.
679897000038	HMMPfam hit to PF00986, DNA_gyraseB_C, score 1.1e-41
679897000039	Superinfection immunity protein; Region: Imm_superinfect; pfam14373
679897000040	2 probable transmembrane helices predicted for HMU00040 by TMHMM2.0 at aa 20-42 and 54-76
679897000041	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39G; cd02423
679897000042	putative active site [active]
679897000043	HMMPfam hit to PF03412, Peptidase_C39, score 3.1e-08
679897000044	2 probable transmembrane helices predicted for HMU00060 by TMHMM2.0 at aa 33-55 and 70-92
679897000045	Signal peptide predicted for HMU00070 by SignalP 2.0 HMM (Signal peptide probability 0.679) with cleavage site probability 0.679 between residues 20 and 21
679897000046	1 probable transmembrane helix predicted for HMU00080 by TMHMM2.0 at aa 48-67
679897000047	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
679897000048	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
679897000049	NAD binding site [chemical binding]; other site
679897000050	homodimer interface [polypeptide binding]; other site
679897000051	active site
679897000052	substrate binding site [chemical binding]; other site
679897000053	HMMPfam hit to PF01370, Epimerase, score 7.6e-58
679897000054	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
679897000055	HMMPfam hit to PF03061, 4HBT, score 2.3e-16
679897000056	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
679897000057	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK03946
679897000058	HMMPfam hit to PF04166, PdxA, score 1.5e-93
679897000059	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
679897000060	active site
679897000061	hydrophilic channel; other site
679897000062	dimerization interface [polypeptide binding]; other site
679897000063	catalytic residues [active]
679897000064	active site lid [active]
679897000065	HMMPfam hit to PF03740, PdxJ, score 7.7e-106
679897000066	HMMPfam hit to PF01856, HP_OMP, score 0.0015
679897000067	2 probable transmembrane helices predicted for HMU00140 by TMHMM2.0 at aa 5-27 and 69-91
679897000068	Signal peptide predicted for HMU00140 by SignalP 2.0 HMM (Signal peptide probability 0.946) with cleavage site probability 0.446 between residues 24 and 25
679897000069	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
679897000070	HMMPfam hit to PF01856, HP_OMP, score 0.00077
679897000071	Signal peptide predicted for HMU00150 by SignalP 2.0 HMM (Signal peptide probability 0.975) with cleavage site probability 0.926 between residues 21 and 22
679897000072	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
679897000073	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
679897000074	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
679897000075	HMMPfam hit to PF07244, Surf_Ag_VNR, score 9.7e-05
679897000076	HMMPfam hit to PF08479, POTRA_2, score 0.00038
679897000077	Signal peptide predicted for HMU00160 by SignalP 2.0 HMM (Signal peptide probability 0.829) with cleavage site probability 0.752 between residues 18 and 19
679897000078	haemagglutination activity domain; Region: Haemagg_act; pfam05860
679897000079	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
679897000080	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
679897000081	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
679897000082	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000083	HMMPfam hit to PF05594, Fil_haemagg, score 0.62
679897000084	HMMPfam hit to PF05860, Haemagg_act, score 3.9e-37
679897000085	Signal peptide predicted for HMU00170 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.729 between residues 23 and 24
679897000086	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
679897000087	HMMPfam hit to PF01856, HP_OMP, score 5.5e-06
679897000088	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
679897000089	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897000090	S-adenosylmethionine binding site [chemical binding]; other site
679897000091	HMMPfam hit to PF02353, CMAS, score 1.9e-147
679897000092	CRISPR
679897000093	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09638
679897000094	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656
679897000095	Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms]; Region: COG3513
679897000096	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
679897000097	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
679897000098	HMMPfam hit to PF01856, HP_OMP, score 2.7e-07
679897000099	1 probable transmembrane helix predicted for HMU00260 by TMHMM2.0 at aa 5-24
679897000100	Protein of unknown function (DUF354); Region: DUF354; pfam04007
679897000101	fructose-1,6-bisphosphatase; Provisional; Region: PRK09293
679897000102	active site
679897000103	HMMPfam hit to PF00316, FBPase, score 5.5e-45
679897000104	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
679897000105	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
679897000106	substrate binding site [chemical binding]; other site
679897000107	hexamer interface [polypeptide binding]; other site
679897000108	metal binding site [ion binding]; metal-binding site
679897000109	HMMPfam hit to PF00834, Ribul_P_3_epim, score 2e-108
679897000110	PS01085 Ribulose-phosphate 3-epimerase family signature 1.
679897000111	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
679897000112	active site
679897000113	catalytic site [active]
679897000114	substrate binding site [chemical binding]; other site
679897000115	HMMPfam hit to PF00929, Exonuc_X-T, score 7.6e-37
679897000116	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
679897000117	HMMPfam hit to PF01515, PTA_PTB, score 8.7e-25
679897000118	Acetokinase family; Region: Acetate_kinase; cl17229
679897000119	propionate/acetate kinase; Provisional; Region: PRK12379
679897000120	HMMPfam hit to PF00871, Acetate_kinase, score 5.9e-125
679897000121	PS01075 Acetate and butyrate kinases family signature 1.
679897000122	PS01076 Acetate and butyrate kinases family signature 2.
679897000123	KpsF/GutQ family protein; Region: kpsF; TIGR00393
679897000124	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
679897000125	putative active site [active]
679897000126	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
679897000127	HMMPfam hit to PF00571, CBS, score 1.8e-16
679897000128	HMMPfam hit to PF01380, SIS, score 1.6e-29
679897000129	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
679897000130	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
679897000131	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
679897000132	HMMPfam hit to PF07521, RMMBL, score 2.2e-12
679897000133	PS01292 Uncharacterized protein family UPF0036 signature.
679897000134	HMMPfam hit to PF00753, Lactamase_B, score 3e-23
679897000135	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
679897000136	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897000137	S-adenosylmethionine binding site [chemical binding]; other site
679897000138	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
679897000139	HMMPfam hit to PF00398, RrnaAD, score 1.5e-42
679897000140	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
679897000141	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
679897000142	substrate binding site [chemical binding]; other site
679897000143	glutamase interaction surface [polypeptide binding]; other site
679897000144	HMMPfam hit to PF00977, His_biosynth, score 4.1e-116
679897000145	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
679897000146	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14462
679897000147	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
679897000148	FeS/SAM binding site; other site
679897000149	HMMPfam hit to PF04055, Radical_SAM, score 2.1e-13
679897000150	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases and ATP sulphurylases. The domain forms a apha/beta/apha fold which  binds to Adenosine group; Region: Alpha_ANH_like; cd01986
679897000151	Ligand Binding Site [chemical binding]; other site
679897000153	Transposase domain (DUF772); Region: DUF772; pfam05598
679897000154	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
679897000155	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
679897000156	HMMPfam hit to PF01609, Transposase_11, score 5e-45
679897000157	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
679897000158	HMMPfam hit to PF07977, FabA, score 1.8e-41
679897000159	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
679897000160	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
679897000161	active site
679897000162	HMMPfam hit to PF00132, Hexapep, score 0.00068
679897000163	PS00101 Hexapeptide-repeat containing-transferases signature.
679897000164	HMMPfam hit to PF00132, Hexapep, score 0.18
679897000165	HMMPfam hit to PF00132, Hexapep, score 0.62
679897000166	HMMPfam hit to PF00132, Hexapep, score 97
679897000167	HMMPfam hit to PF00132, Hexapep, score 1.7
679897000168	HMMPfam hit to PF00132, Hexapep, score 0.04
679897000169	HMMPfam hit to PF00132, Hexapep, score 3.9
679897000170	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
679897000171	ClpX C4-type zinc finger; Region: zf-C4_ClpX; cl05964
679897000172	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897000173	Walker A motif; other site
679897000174	ATP binding site [chemical binding]; other site
679897000175	Walker B motif; other site
679897000176	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
679897000177	HMMPfam hit to PF07724, AAA_2, score 2.2e-76
679897000178	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000179	rod shape-determining protein MreB; Provisional; Region: PRK13927
679897000180	MreB and similar proteins; Region: MreB_like; cd10225
679897000181	nucleotide binding site [chemical binding]; other site
679897000182	Mg binding site [ion binding]; other site
679897000183	putative protofilament interaction site [polypeptide binding]; other site
679897000184	RodZ interaction site [polypeptide binding]; other site
679897000185	HMMPfam hit to PF06723, MreB_Mbl, score 1.4e-211
679897000186	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000187	rod shape-determining protein MreC; Provisional; Region: PRK13922
679897000188	rod shape-determining protein MreC; Region: MreC; pfam04085
679897000189	Signal peptide predicted for HMU00480 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.253 between residues 27 and 28
679897000190	1 probable transmembrane helix predicted for HMU00480 by TMHMM2.0 at aa 5-22
679897000191	HMMPfam hit to PF04085, MreC, score 6.7e-14
679897000192	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
679897000193	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
679897000194	HMMPfam hit to PF00534, Glycos_transf_1, score 0.00095
679897000195	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
679897000196	ligand binding site [chemical binding]; other site
679897000197	active site
679897000198	UGI interface [polypeptide binding]; other site
679897000199	catalytic site [active]
679897000200	HMMPfam hit to PF03167, UDG, score 5.2e-61
679897000201	PS00130 Uracil-DNA glycosylase signature.
679897000202	L-lactate permease; Region: Lactate_perm; cl00701
679897000203	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
679897000204	13 probable transmembrane helices predicted for HMU00520 by TMHMM2.0 at aa 12-34, 39-61, 68-90, 128-150, 157-179, 194-216, 223-241, 251-268, 289-311, 368-387, 400-422, 442-459 and 528-550
679897000205	HMMPfam hit to PF02652, Lactate_perm, score 2.6e-267
679897000206	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000207	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
679897000208	active site residue [active]
679897000209	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
679897000210	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
679897000211	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
679897000212	dimer interface [polypeptide binding]; other site
679897000213	motif 1; other site
679897000214	active site
679897000215	motif 2; other site
679897000216	motif 3; other site
679897000217	HMMPfam hit to PF02912, Phe_tRNA-synt_N, score 5.3e-18
679897000218	HMMPfam hit to PF01409, tRNA-synt_2d, score 3.6e-145
679897000219	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
679897000220	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
679897000221	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
679897000222	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
679897000223	putative tRNA-binding site [nucleotide binding]; other site
679897000224	B3/4 domain; Region: B3_4; pfam03483
679897000225	tRNA synthetase B5 domain; Region: B5; smart00874
679897000226	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
679897000227	dimer interface [polypeptide binding]; other site
679897000228	motif 1; other site
679897000229	motif 3; other site
679897000230	motif 2; other site
679897000231	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
679897000232	HMMPfam hit to PF01588, tRNA_bind, score 3.8e-27
679897000233	HMMPfam hit to PF03484, B5, score 9.7e-22
679897000234	HMMPfam hit to PF03147, FDX-ACB, score 4.2e-12
679897000235	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
679897000236	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
679897000237	hinge; other site
679897000238	active site
679897000239	HMMPfam hit to PF00275, EPSP_synthase, score 6e-137
679897000240	PS00104 EPSP synthase signature 1.
679897000241	PS00885 EPSP synthase signature 2.
679897000242	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
679897000243	LytB protein; Region: LYTB; pfam02401
679897000244	HMMPfam hit to PF02401, LYTB, score 7.5e-120
679897000245	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
679897000246	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
679897000247	active site
679897000248	catalytic site [active]
679897000249	metal binding site [ion binding]; metal-binding site
679897000250	HMMPfam hit to PF03009, GDPD, score 1.2e-93
679897000251	Signal peptide predicted for HMU00580 by SignalP 2.0 HMM (Signal peptide probability 0.969) with cleavage site probability 0.575 between residues 26 and 27
679897000252	1 probable transmembrane helix predicted for HMU00580 by TMHMM2.0 at aa 5-24
679897000253	glycerol-3-phosphate transporter; Region: glpT; TIGR00712
679897000254	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
679897000255	putative substrate translocation pore; other site
679897000256	11 probable transmembrane helices predicted for HMU00590 by TMHMM2.0 at aa 26-45, 66-88, 108-130, 164-186, 201-220, 267-286, 306-325, 337-359, 379-401, 413-435 and 445-464
679897000257	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000258	HMMPfam hit to PF07690, MFS_1, score 3.8e-48
679897000259	PS00942 glpT family of transporters signature.
679897000260	Autotransporter beta-domain; Region: Autotransporter; pfam03797
679897000261	PS00430 TonB-dependent receptor proteins signature 1.
679897000262	Signal peptide predicted for HMU00600 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.469 between residues 33 and 34
679897000263	HMMPfam hit to PF03797, Autotransporter, score 3.7e-17
679897000264	Autotransporter beta-domain; Region: Autotransporter; pfam03797
679897000265	HMMPfam hit to PF03797, Autotransporter, score 3.7e-17
679897000266	1 probable transmembrane helix predicted for HMU00620 by TMHMM2.0 at aa 12-34
679897000267	Signal peptide predicted for HMU00620 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.406 between residues 33 and 34
679897000268	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000269	Autotransporter beta-domain; Region: Autotransporter; pfam03797
679897000270	Signal peptide predicted for HMU00630 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.780 between residues 48 and 49
679897000271	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000272	HMMPfam hit to PF03797, Autotransporter, score 4.5e-17
679897000273	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
679897000274	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
679897000275	PS00092 N-6 Adenine-specific DNA methylases signature.
679897000276	Catalytic domain of Protein Kinases; Region: PKc; cd00180
679897000277	active site
679897000278	ATP binding site [chemical binding]; other site
679897000279	substrate binding site [chemical binding]; other site
679897000280	activation loop (A-loop); other site
679897000281	HMMPfam hit to PF00069, Pkinase, score 1e-19
679897000282	PS00107 Protein kinases ATP-binding region signature.
679897000283	PS00109 Tyrosine protein kinases specific active-site signature.
679897000284	Pentapeptide repeats (9 copies); Region: Pentapeptide_3; pfam13576
679897000285	4 probable transmembrane helices predicted for HMU00660 by TMHMM2.0 at aa 494-516, 546-568, 575-597 and 612-631
679897000286	Abi-like protein; Region: Abi_2; pfam07751
679897000287	HMMPfam hit to PF07751, Abi_2, score 3.5e-24
679897000288	Signal peptide predicted for HMU00690 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.988 between residues 20 and 21
679897000289	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
679897000290	6 probable transmembrane helices predicted for HMU00700 by TMHMM2.0 at aa 33-55, 91-110, 117-139, 149-171, 178-200 and 210-232
679897000291	Dihydroneopterin aldolase; Region: FolB; pfam02152
679897000292	active site
679897000293	HMMPfam hit to PF02152, FolB, score 2.8e-08
679897000294	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
679897000295	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
679897000296	Signal peptide predicted for HMU00720 by SignalP 2.0 HMM (Signal peptide probability 0.952) with cleavage site probability 0.424 between residues 20 and 21
679897000297	HMMPfam hit to PF07715, Plug, score 1.1e-16
679897000298	HMMPfam hit to PF00593, TonB_dep_Rec, score 7.4e-21
679897000299	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
679897000300	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
679897000301	Signal peptide predicted for HMU00730 by SignalP 2.0 HMM (Signal peptide probability 0.925) with cleavage site probability 0.446 between residues 25 and 26
679897000302	HMMPfam hit to PF07715, Plug, score 3.6e-17
679897000303	HMMPfam hit to PF00593, TonB_dep_Rec, score 2.9e-22
679897000304	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
679897000305	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
679897000306	G1 box; other site
679897000307	GTP/Mg2+ binding site [chemical binding]; other site
679897000308	Switch I region; other site
679897000309	G2 box; other site
679897000310	G3 box; other site
679897000311	Switch II region; other site
679897000312	G4 box; other site
679897000313	G5 box; other site
679897000314	Nucleoside recognition; Region: Gate; pfam07670
679897000315	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
679897000316	Nucleoside recognition; Region: Gate; pfam07670
679897000317	9 probable transmembrane helices predicted for HMU00740 by TMHMM2.0 at aa 300-322, 353-375, 405-422, 435-457, 462-484, 520-542, 614-636, 657-679 and 689-711
679897000318	HMMPfam hit to PF07670, Gate, score 4e-16
679897000319	HMMPfam hit to PF07664, FeoB_C, score 1.5e-18
679897000320	HMMPfam hit to PF07670, Gate, score 1.1e-16
679897000321	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000322	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000323	HMMPfam hit to PF02421, FeoB_N, score 4e-29
679897000324	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
679897000325	HMMPfam hit to PF01926, MMR_HSR1, score 2.8e-30
679897000326	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000327	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
679897000328	S1 domain; Region: S1_2; pfam13509
679897000329	S1 domain; Region: S1_2; pfam13509
679897000330	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
679897000331	Signal peptide predicted for HMU00760 by SignalP 2.0 HMM (Signal peptide probability 0.861) with cleavage site probability 0.359 between residues 23 and 24
679897000332	Ferric reductase like transmembrane component; Region: Ferric_reduct; cl01043
679897000333	6 probable transmembrane helices predicted for HMU00770 by TMHMM2.0 at aa 7-25, 35-57, 64-86, 101-123, 130-147 and 151-169
679897000334	HMMPfam hit to PF01794, Ferric_reduct, score 0.00046
679897000335	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
679897000336	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
679897000337	Ligand binding site; other site
679897000338	oligomer interface; other site
679897000339	HMMPfam hit to PF02348, CTP_transf_3, score 1.2e-57
679897000340	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
679897000341	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
679897000342	DNA binding site [nucleotide binding]
679897000343	active site
679897000344	HMMPfam hit to PF01035, DNA_binding_1, score 1.3e-28
679897000345	PS00374 Methylated-DNA--protein-cysteine methyltransferase active site.
679897000346	AIR carboxylase; Region: AIRC; smart01001
679897000347	HMMPfam hit to PF00731, AIRC, score 3.4e-70
679897000348	META domain; Region: META; pfam03724
679897000349	Signal peptide predicted for HMU00810 by SignalP 2.0 HMM (Signal peptide probability 0.930) with cleavage site probability 0.374 between residues 24 and 25
679897000350	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000351	O-Antigen ligase; Region: Wzy_C; pfam04932
679897000352	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
679897000353	Signal peptide predicted for HMU00830 by SignalP 2.0 HMM (Signal peptide probability 0.716) with cleavage site probability 0.526 between residues 57 and 58
679897000354	11 probable transmembrane helices predicted for HMU00830 by TMHMM2.0 at aa 7-24, 28-47, 67-89, 99-116, 123-145, 167-189, 196-218, 238-260, 345-367, 382-404 and 411-428
679897000355	HMMPfam hit to PF04932, Wzy_C, score 1.7e-07
679897000356	Glycosyltransferase like family 2; Region: Glyco_tranf_2_2; pfam10111
679897000357	N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase; Region: GT2_Chondriotin_Pol_N; cd06420
679897000358	Substrate binding site; other site
679897000359	metal-binding site
679897000360	HMMPfam hit to PF00535, Glycos_transf_2, score 8.1e-26
679897000361	flagellar hook protein FlgE; Validated; Region: flgE; PRK08425
679897000362	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
679897000363	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
679897000364	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
679897000365	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000366	HMMPfam hit to PF07559, FlaE, score 4.4e-34
679897000367	HMMPfam hit to PF07196, Flagellin_IN, score 8.3e-09
679897000368	HMMPfam hit to PF00460, Flg_bb_rod, score 6.9e-06
679897000369	Signal peptide predicted for HMU00860 by SignalP 2.0 HMM (Signal peptide probability 0.621) with cleavage site probability 0.507 between residues 17 and 18
679897000370	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
679897000371	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
679897000372	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
679897000373	HMMPfam hit to PF01678, DAP_epimerase, score 5.9e-06
679897000374	HMMPfam hit to PF01678, DAP_epimerase, score 2.2e-20
679897000375	PS01326 Diaminopimelate epimerase signature.
679897000376	potential protein location (hypothetical protein HMU00880 [Helicobacter mustelae 12198]) that overlaps RNA (tRNA-H)
679897000377	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
679897000378	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
679897000379	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
679897000380	Walker A/P-loop; other site
679897000381	ATP binding site [chemical binding]; other site
679897000382	Q-loop/lid; other site
679897000383	ABC transporter signature motif; other site
679897000384	Walker B; other site
679897000385	D-loop; other site
679897000386	H-loop/switch region; other site
679897000387	HMMPfam hit to PF00005, ABC_tran, score 2e-60
679897000388	PS00211 ABC transporters family signature.
679897000389	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000390	5 probable transmembrane helices predicted for HMU00890 by TMHMM2.0 at aa 24-46, 80-102, 159-181, 185-203 and 271-290
679897000391	Signal peptide predicted for HMU00890 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.469 between residues 45 and 46
679897000392	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
679897000393	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
679897000394	NADP binding site [chemical binding]; other site
679897000395	active site
679897000396	putative substrate binding site [chemical binding]; other site
679897000397	HMMPfam hit to PF01370, Epimerase, score 1.6e-91
679897000398	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
679897000399	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
679897000400	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
679897000401	catalytic residue [active]
679897000402	HMMPfam hit to PF00266, Aminotran_5, score 1.6e-23
679897000403	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
679897000404	nucleotide binding site/active site [active]
679897000405	HIT family signature motif; other site
679897000406	catalytic residue [active]
679897000407	HMMPfam hit to PF01230, HIT, score 1e-35
679897000408	biotin synthase; Provisional; Region: PRK08508
679897000409	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
679897000410	FeS/SAM binding site; other site
679897000411	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
679897000412	HMMPfam hit to PF06968, BATS, score 1.4e-17
679897000413	HMMPfam hit to PF04055, Radical_SAM, score 9.4e-22
679897000414	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
679897000415	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
679897000416	RNA binding site [nucleotide binding]; other site
679897000417	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
679897000418	RNA binding site [nucleotide binding]; other site
679897000419	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
679897000420	RNA binding site [nucleotide binding]; other site
679897000421	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
679897000422	RNA binding site [nucleotide binding]; other site
679897000423	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
679897000424	RNA binding site [nucleotide binding]; other site
679897000425	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
679897000426	RNA binding site [nucleotide binding]; other site
679897000427	HMMPfam hit to PF00575, S1, score 1.2e-06
679897000428	HMMPfam hit to PF00575, S1, score 7.9e-20
679897000429	HMMPfam hit to PF00575, S1, score 3.8e-25
679897000430	HMMPfam hit to PF00575, S1, score 9.1e-13
679897000431	HMMPfam hit to PF00575, S1, score 0.00046
679897000432	HMMPfam hit to PF00575, S1, score 0.0018
679897000433	EamA-like transporter family; Region: EamA; pfam00892
679897000434	10 probable transmembrane helices predicted for HMU00960 by TMHMM2.0 at aa 13-30, 40-57, 70-92, 96-118, 125-147, 162-184, 196-218, 274-296, 303-325 and 329-351
679897000435	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000436	Family description; Region: ACT_7; pfam13840
679897000437	L-lysine exporter; Region: 2a75; TIGR00948
679897000438	Signal peptide predicted for HMU00990 by SignalP 2.0 HMM (Signal peptide probability 0.968) with cleavage site probability 0.461 between residues 21 and 22
679897000439	5 probable transmembrane helices predicted for HMU00990 by TMHMM2.0 at aa 5-27, 37-59, 66-88, 146-168 and 180-202
679897000440	HMMPfam hit to PF01810, LysE, score 3.8e-35
679897000441	A-factor biosynthesis hotdog domain; Region: AfsA; pfam03756
679897000442	potential protein location (hypothetical protein HMU01000 [Helicobacter mustelae 12198]) that overlaps RNA (23S ribosomal RNA)
679897000443	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
679897000444	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
679897000445	Walker A/P-loop; other site
679897000446	ATP binding site [chemical binding]; other site
679897000447	Q-loop/lid; other site
679897000448	ABC transporter signature motif; other site
679897000449	Walker B; other site
679897000450	D-loop; other site
679897000451	H-loop/switch region; other site
679897000452	HMMPfam hit to PF00005, ABC_tran, score 4.2e-15
679897000453	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000454	HMMPfam hit to PF01061, ABC2_membrane, score 1e-08
679897000455	7 probable transmembrane helices predicted for HMU01050 by TMHMM2.0 at aa 20-40, 47-69, 79-101, 106-128, 132-154, 163-185 and 218-240
679897000456	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000457	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
679897000458	HMMPfam hit to PF01856, HP_OMP, score 3.5e-13
679897000459	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
679897000460	Fumarase C-terminus; Region: Fumerase_C; cl00795
679897000461	HMMPfam hit to PF05683, Fumerase_C, score 7.9e-61
679897000462	fumarate hydratase; Provisional; Region: PRK06246
679897000463	HMMPfam hit to PF05681, Fumerase, score 4.5e-159
679897000464	PS00228 Tubulin-beta mRNA autoregulation signal.
679897000465	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
679897000466	1 probable transmembrane helix predicted for HMU01100 by TMHMM2.0 at aa 7-24
679897000467	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
679897000468	HMMPfam hit to PF00902, TatC, score 4.6e-84
679897000469	6 probable transmembrane helices predicted for HMU01110 by TMHMM2.0 at aa 16-38, 72-94, 106-128, 155-177, 190-207 and 212-234
679897000470	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000471	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
679897000472	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
679897000473	HMMPfam hit to PF02547, Queuosine_synth, score 3.8e-89
679897000474	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
679897000475	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
679897000476	PS00228 Tubulin-beta mRNA autoregulation signal.
679897000477	HMMPfam hit to PF02527, GidB, score 1.4e-39
679897000478	Signal peptide predicted for HMU01140 by SignalP 2.0 HMM (Signal peptide probability 0.742) with cleavage site probability 0.276 between residues 27 and 28
679897000479	1 probable transmembrane helix predicted for HMU01140 by TMHMM2.0 at aa 4-18
679897000480	putative recombination protein RecO; Provisional; Region: PRK13908
679897000481	Competence-damaged protein; Region: CinA; pfam02464
679897000482	HMMPfam hit to PF02464, CinA, score 4e-36
679897000483	Autotransporter beta-domain; Region: Autotransporter; pfam03797
679897000484	HMMPfam hit to PF03797, Autotransporter, score 5e-15
679897000485	Autotransporter beta-domain; Region: Autotransporter; pfam03797
679897000486	PS00107 Protein kinases ATP-binding region signature.
679897000487	HMMPfam hit to PF03797, Autotransporter, score 5e-15
679897000488	Signal peptide predicted for HMU01200 by SignalP 2.0 HMM (Signal peptide probability 0.878) with cleavage site probability 0.314 between residues 22 and 23
679897000489	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
679897000490	dimer interface [polypeptide binding]; other site
679897000491	catalytic triad [active]
679897000492	peroxidatic and resolving cysteines [active]
679897000493	HMMPfam hit to PF08534, Redoxin, score 7e-40
679897000494	PS01265 Tpx family signature.
679897000495	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
679897000496	Domain of unknown function DUF20; Region: UPF0118; pfam01594
679897000497	HMMPfam hit to PF01594, UPF0118, score 3.4e-38
679897000498	8 probable transmembrane helices predicted for HMU01220 by TMHMM2.0 at aa 7-23, 27-44, 56-78, 152-174, 194-216, 226-248, 268-290 and 305-336
679897000499	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
679897000500	HMMPfam hit to PF01856, HP_OMP, score 3.2e-05
679897000501	Signal peptide predicted for HMU01230 by SignalP 2.0 HMM (Signal peptide probability 0.972) with cleavage site probability 0.415 between residues 16 and 17
679897000502	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
679897000503	PS00190 Cytochrome c family heme-binding site signature.
679897000504	HMMPfam hit to PF03150, CCP_MauG, score 3.2e-85
679897000505	PS00190 Cytochrome c family heme-binding site signature.
679897000506	Signal peptide predicted for HMU01240 by SignalP 2.0 HMM (Signal peptide probability 0.878) with cleavage site probability 0.785 between residues 16 and 17
679897000507	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
679897000508	Na2 binding site [ion binding]; other site
679897000509	putative substrate binding site 1 [chemical binding]; other site
679897000510	Na binding site 1 [ion binding]; other site
679897000511	putative substrate binding site 2 [chemical binding]; other site
679897000512	HMMPfam hit to PF00209, SNF, score 3.9e-13
679897000513	11 probable transmembrane helices predicted for HMU01250 by TMHMM2.0 at aa 5-27, 37-59, 96-118, 155-177, 190-212, 227-249, 262-284, 318-340, 353-375, 393-415 and 436-458
679897000514	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
679897000515	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
679897000516	hexamer interface [polypeptide binding]; other site
679897000517	ligand binding site [chemical binding]; other site
679897000518	putative active site [active]
679897000519	NAD(P) binding site [chemical binding]; other site
679897000520	HMMPfam hit to PF05222, AlaDh_PNT_N, score 5.6e-65
679897000521	HMMPfam hit to PF01262, AlaDh_PNT_C, score 1.5e-74
679897000522	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
679897000523	Signal peptide predicted for HMU01270 by SignalP 2.0 HMM (Signal peptide probability 0.942) with cleavage site probability 0.732 between residues 33 and 34
679897000524	1 probable transmembrane helix predicted for HMU01270 by TMHMM2.0 at aa 7-29
679897000525	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
679897000526	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
679897000527	14 probable transmembrane helices predicted for HMU01280 by TMHMM2.0 at aa 13-32, 47-69, 76-98, 302-319, 340-357, 637-656, 668-690, 700-719, 726-745, 760-791, 812-834, 849-868, 873-895 and 910-932
679897000528	HMMPfam hit to PF01578, Cytochrom_C_asm, score 2.2e-50
679897000529	Signal peptide predicted for HMU01280 by SignalP 2.0 HMM (Signal peptide probability 0.804) with cleavage site probability 0.389 between residues 33 and 34
679897000530	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
679897000531	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000532	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
679897000533	ferrochelatase; Reviewed; Region: hemH; PRK00035
679897000534	C-terminal domain interface [polypeptide binding]; other site
679897000535	active site
679897000536	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
679897000537	active site
679897000538	N-terminal domain interface [polypeptide binding]; other site
679897000539	HMMPfam hit to PF00762, Ferrochelatase, score 7.4e-103
679897000540	PS00534 Ferrochelatase signature.
679897000541	4 probable transmembrane helices predicted for HMU01310 by TMHMM2.0 at aa 19-36, 48-70, 80-102 and 115-137
679897000542	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
679897000543	RNA methyltransferase, RsmE family; Region: TIGR00046
679897000544	transcription elongation factor NusA; Provisional; Region: nusA; PRK12328
679897000545	NusA N-terminal domain; Region: NusA_N; pfam08529
679897000546	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
679897000547	RNA binding site [nucleotide binding]; other site
679897000548	homodimer interface [polypeptide binding]; other site
679897000549	NusA-like KH domain; Region: KH_5; pfam13184
679897000550	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
679897000551	G-X-X-G motif; other site
679897000552	HMMPfam hit to PF08529, NusA_N, score 9.7e-05
679897000553	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
679897000554	RNA polymerases M/15 Kd subunit; Region: RNA_POL_M_15KD; cl02717
679897000555	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
679897000556	HMMPfam hit to PF01039, Carboxyl_trans, score 1.7e-08
679897000557	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
679897000558	DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734
679897000559	HMMPfam hit to PF01258, zf-dskA_traR, score 3.3e-06
679897000560	PS01102 Prokaryotic dksA/traR C4-type zinc finger.
679897000561	2 probable transmembrane helices predicted for HMU01370 by TMHMM2.0 at aa 5-27 and 40-62
679897000562	peptide chain release factor 1; Validated; Region: prfA; PRK00591
679897000563	This domain is found in peptide chain release factors; Region: PCRF; smart00937
679897000564	RF-1 domain; Region: RF-1; pfam00472
679897000565	HMMPfam hit to PF00472, RF-1, score 1.7e-71
679897000566	PS00745 Prokaryotic-type class I peptide chain release factors signature.
679897000567	HMMPfam hit to PF03462, PCRF, score 1.5e-60
679897000568	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
679897000569	HMMPfam hit to PF01649, Ribosomal_S20p, score 5.4e-39
679897000570	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14324
679897000571	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
679897000572	active site
679897000573	substrate binding site [chemical binding]; other site
679897000574	metal binding site [ion binding]; metal-binding site
679897000575	HMMPfam hit to PF02878, PGM_PMM_I, score 2.5e-61
679897000576	PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature.
679897000577	HMMPfam hit to PF02879, PGM_PMM_II, score 5.4e-35
679897000578	HMMPfam hit to PF02880, PGM_PMM_III, score 3e-29
679897000579	HMMPfam hit to PF00408, PGM_PMM_IV, score 2.8e-07
679897000580	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
679897000581	lipoprotein signal peptidase; Provisional; Region: PRK14787
679897000582	HMMPfam hit to PF01252, Peptidase_A8, score 1.7e-33
679897000583	4 probable transmembrane helices predicted for HMU01410 by TMHMM2.0 at aa 5-24, 57-79, 84-103 and 123-145
679897000584	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
679897000585	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
679897000586	FeS/SAM binding site; other site
679897000587	HMMPfam hit to PF06969, HemN_C, score 2.1e-12
679897000588	HMMPfam hit to PF04055, Radical_SAM, score 5e-18
679897000589	Cytochrome c; Region: Cytochrom_C; cl11414
679897000590	Signal peptide predicted for HMU01430 by SignalP 2.0 HMM (Signal peptide probability 0.924) with cleavage site probability 0.672 between residues 17 and 18
679897000591	HMMPfam hit to PF00034, Cytochrom_C, score 0.0031
679897000592	PS00190 Cytochrome c family heme-binding site signature.
679897000593	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
679897000594	putative active site [active]
679897000595	Ap4A binding site [chemical binding]; other site
679897000596	nudix motif; other site
679897000597	putative metal binding site [ion binding]; other site
679897000598	HMMPfam hit to PF00293, NUDIX, score 9.9e-27
679897000599	PS00893 mutT domain signature.
679897000600	aspartate kinase; Reviewed; Region: PRK06635
679897000601	AAK_AK-DapG-like: Amino Acid Kinase Superfamily (AAK), AK-DapG-like; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the diaminopimelate-sensitive aspartokinase isoenzyme AKI (DapG), a monofunctional enzymes found in Bacilli; Region: AAK_AK-DapG-like; cd04246
679897000602	putative catalytic residues [active]
679897000603	putative nucleotide binding site [chemical binding]; other site
679897000604	putative aspartate binding site [chemical binding]; other site
679897000605	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
679897000606	putative allosteric regulatory site; other site
679897000607	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
679897000608	putative allosteric regulatory residue; other site
679897000609	HMMPfam hit to PF00696, AA_kinase, score 6.7e-72
679897000610	PS00324 Aspartokinase signature.
679897000611	HMMPfam hit to PF01842, ACT, score 6.3e-13
679897000612	HMMPfam hit to PF01842, ACT, score 3.8e-07
679897000613	DNA replication regulator; Region: HobA; pfam12163
679897000614	DNA polymerase III subunit delta'; Validated; Region: PRK08485
679897000615	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
679897000616	dihydropteroate synthase; Region: DHPS; TIGR01496
679897000617	substrate binding pocket [chemical binding]; other site
679897000618	dimer interface [polypeptide binding]; other site
679897000619	inhibitor binding site; inhibition site
679897000620	HMMPfam hit to PF00809, Pterin_bind, score 2.9e-76
679897000621	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
679897000622	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
679897000623	active site
679897000624	PHP Thumb interface [polypeptide binding]; other site
679897000625	metal binding site [ion binding]; metal-binding site
679897000626	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
679897000627	generic binding surface II; other site
679897000628	generic binding surface I; other site
679897000629	HMMPfam hit to PF02811, PHP, score 1.3e-75
679897000630	HMMPfam hit to PF07733, DNA_pol3_alpha, score 1.4e-281
679897000631	HMMPfam hit to PF01336, tRNA_anti, score 3.4e-08
679897000632	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
679897000633	S4 RNA-binding domain; Region: S4; smart00363
679897000634	RNA binding surface [nucleotide binding]; other site
679897000635	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
679897000636	active site
679897000637	HMMPfam hit to PF01479, S4, score 1.8e-05
679897000638	HMMPfam hit to PF00849, PseudoU_synth_2, score 8.5e-10
679897000639	PS01149 Rsu family of pseudouridine synthase signature.
679897000640	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
679897000641	Signal peptide predicted for HMU01530 by SignalP 2.0 HMM (Signal peptide probability 0.806) with cleavage site probability 0.348 between residues 21 and 22
679897000642	phosphoserine phosphatase SerB; Region: serB; TIGR00338
679897000643	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
679897000644	motif II; other site
679897000645	HMMPfam hit to PF00702, Hydrolase, score 1.4e-18
679897000646	PS00041 Bacterial regulatory proteins, araC family signature.
679897000647	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
679897000648	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
679897000649	ligand binding site [chemical binding]; other site
679897000650	NAD binding site [chemical binding]; other site
679897000651	dimerization interface [polypeptide binding]; other site
679897000652	catalytic site [active]
679897000653	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
679897000654	HMMPfam hit to PF01842, ACT, score 3.9e-05
679897000655	HMMPfam hit to PF00389, 2-Hacid_dh, score 2.4e-43
679897000656	HMMPfam hit to PF02826, 2-Hacid_dh_C, score 6e-83
679897000657	PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3.
679897000658	PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature.
679897000659	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000660	Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT); Region: AGAT_like; cd06451
679897000661	homodimer interface [polypeptide binding]; other site
679897000662	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897000663	catalytic residue [active]
679897000664	HMMPfam hit to PF00266, Aminotran_5, score 1.7e-36
679897000665	PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site.
679897000666	Signal peptide predicted for HMU01560 by SignalP 2.0 HMM (Signal peptide probability 0.686) with cleavage site probability 0.398 between residues 24 and 25
679897000667	Signal peptide predicted for HMU01570 by SignalP 2.0 HMM (Signal peptide probability 0.864) with cleavage site probability 0.463 between residues 24 and 25
679897000668	pantoate--beta-alanine ligase; Region: panC; TIGR00018
679897000669	Pantoate-beta-alanine ligase; Region: PanC; cd00560
679897000670	active site
679897000671	ATP-binding site [chemical binding]; other site
679897000672	pantoate-binding site; other site
679897000673	HXXH motif; other site
679897000674	HMMPfam hit to PF02569, Pantoate_ligase, score 1e-122
679897000675	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
679897000676	active site
679897000677	dimer interface [polypeptide binding]; other site
679897000678	HMMPfam hit to PF00215, OMPdecase, score 3.7e-63
679897000679	PS00156 Orotidine 5'-phosphate decarboxylase active site.
679897000680	1 probable transmembrane helix predicted for HMU01600 by TMHMM2.0 at aa 18-40
679897000681	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
679897000682	active site clefts [active]
679897000683	zinc binding site [ion binding]; other site
679897000684	dimer interface [polypeptide binding]; other site
679897000685	HMMPfam hit to PF00484, Pro_CA, score 1.8e-44
679897000686	PS00705 Prokaryotic-type carbonic anhydrases signature 2.
679897000687	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
679897000688	HMMPfam hit to PF00793, DAHP_synth_1, score 2.2e-72
679897000689	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
679897000690	homopentamer interface [polypeptide binding]; other site
679897000691	active site
679897000692	HMMPfam hit to PF00885, DMRL_synthase, score 6.7e-74
679897000693	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
679897000694	putative RNA binding site [nucleotide binding]; other site
679897000695	HMMPfam hit to PF01029, NusB, score 1.9e-35
679897000696	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
679897000697	Mechanosensitive ion channel; Region: MS_channel; pfam00924
679897000698	Signal peptide predicted for HMU01650 by SignalP 2.0 HMM (Signal peptide probability 0.941) with cleavage site probability 0.661 between residues 24 and 25
679897000699	7 probable transmembrane helices predicted for HMU01650 by TMHMM2.0 at aa 4-21, 194-216, 231-253, 273-295, 310-332, 345-362 and 366-388
679897000700	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000701	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000702	HMMPfam hit to PF00924, MS_channel, score 1.9e-80
679897000703	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
679897000704	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
679897000705	Mg++ binding site [ion binding]; other site
679897000706	putative catalytic motif [active]
679897000707	putative substrate binding site [chemical binding]; other site
679897000708	Signal peptide predicted for HMU01660 by SignalP 2.0 HMM (Signal peptide probability 0.638) with cleavage site probability 0.423 between residues 41 and 42
679897000709	10 probable transmembrane helices predicted for HMU01660 by TMHMM2.0 at aa 20-42, 63-85, 90-107, 128-146, 166-188, 195-214, 229-251, 256-278, 283-305 and 333-352
679897000710	HMMPfam hit to PF00953, Glycos_transf_4, score 2.9e-56
679897000711	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03815
679897000712	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
679897000713	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
679897000714	HMMPfam hit to PF08245, Mur_ligase_M, score 1.5e-21
679897000715	HMMPfam hit to PF02875, Mur_ligase_C, score 1.7e-05
679897000716	HMMPfam hit to PF01856, HP_OMP, score 0.0032
679897000717	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
679897000718	Signal peptide predicted for HMU01690 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.719 between residues 26 and 27
679897000719	HMMPfam hit to PF01856, HP_OMP, score 5.5e-06
679897000720	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
679897000721	HMMPfam hit to PF01856, HP_OMP, score 1.6e-11
679897000722	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
679897000723	Peptidase family M23; Region: Peptidase_M23; pfam01551
679897000724	Signal peptide predicted for HMU01710 by SignalP 2.0 HMM (Signal peptide probability 0.710) with cleavage site probability 0.694 between residues 29 and 30
679897000725	1 probable transmembrane helix predicted for HMU01710 by TMHMM2.0 at aa 7-24
679897000726	HMMPfam hit to PF01551, Peptidase_M23, score 4.8e-36
679897000727	septum formation inhibitor; Reviewed; Region: minC; PRK00556
679897000728	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
679897000729	HMMPfam hit to PF03775, MinC_C, score 1.1e-07
679897000730	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
679897000731	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
679897000732	HMMPfam hit to PF03331, LpxC, score 3.9e-147
679897000733	homoserine kinase; Provisional; Region: PRK01212
679897000734	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
679897000735	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
679897000736	HMMPfam hit to PF00288, GHMP_kinases_N, score 1.1e-13
679897000737	HMMPfam hit to PF08544, GHMP_kinases_C, score 0.0042
679897000738	Protein of unknown function (DUF448); Region: DUF448; pfam04296
679897000739	putative RNA binding cleft [nucleotide binding]; other site
679897000740	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
679897000741	translation initiation factor IF-2; Region: IF-2; TIGR00487
679897000742	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
679897000743	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
679897000744	G1 box; other site
679897000745	putative GEF interaction site [polypeptide binding]; other site
679897000746	GTP/Mg2+ binding site [chemical binding]; other site
679897000747	Switch I region; other site
679897000748	G2 box; other site
679897000749	G3 box; other site
679897000750	Switch II region; other site
679897000751	G4 box; other site
679897000752	G5 box; other site
679897000753	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
679897000754	Translation-initiation factor 2; Region: IF-2; pfam11987
679897000755	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
679897000756	HMMPfam hit to PF04760, IF2_N, score 4.9e-09
679897000757	HMMPfam hit to PF04760, IF2_N, score 2.1e-15
679897000758	HMMPfam hit to PF00009, GTP_EFTU, score 1.2e-45
679897000759	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000760	HMMPfam hit to PF03144, GTP_EFTU_D2, score 1.8e-09
679897000761	HMMPfam hit to PF03144, GTP_EFTU_D2, score 2.3e-12
679897000762	PS01176 Initiation factor 2 signature.
679897000763	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
679897000764	HMMPfam hit to PF02033, RBFA, score 1.1e-07
679897000765	ribosome maturation protein RimP; Reviewed; Region: PRK00092
679897000766	Sm and related proteins; Region: Sm_like; cl00259
679897000767	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
679897000768	putative oligomer interface [polypeptide binding]; other site
679897000769	putative RNA binding site [nucleotide binding]; other site
679897000770	PS00136 serine proteases, subtilase family, aspartic acid active site.
679897000771	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
679897000772	oligomerization interface [polypeptide binding]; other site
679897000773	active site
679897000774	metal binding site [ion binding]; metal-binding site
679897000775	HMMPfam hit to PF02548, Pantoate_transf, score 1.2e-131
679897000776	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
679897000777	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897000778	Walker A motif; other site
679897000779	ATP binding site [chemical binding]; other site
679897000780	Walker B motif; other site
679897000781	arginine finger; other site
679897000782	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
679897000783	HMMPfam hit to PF05496, RuvB_N, score 2.2e-20
679897000784	HMMPfam hit to PF00004, AAA, score 8.5e-31
679897000785	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000786	HMMPfam hit to PF05491, RuvB_C, score 1.1e-27
679897000787	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
679897000788	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
679897000789	HMMPfam hit to PF07992, Pyr_redox_2, score 4.5e-08
679897000790	HMMPfam hit to PF00070, Pyr_redox, score 2.7e-05
679897000791	shikimate kinase; Reviewed; Region: aroK; PRK00131
679897000792	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
679897000793	ADP binding site [chemical binding]; other site
679897000794	magnesium binding site [ion binding]; other site
679897000795	putative shikimate binding site; other site
679897000796	HMMPfam hit to PF01202, SKI, score 6.9e-47
679897000797	1 probable transmembrane helix predicted for HMU01830 by TMHMM2.0 at aa 64-86
679897000798	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000799	AMIN domain; Region: AMIN; pfam11741
679897000800	Signal peptide predicted for HMU01840 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.870 between residues 24 and 25
679897000801	Signal peptide predicted for HMU01850 by SignalP 2.0 HMM (Signal peptide probability 0.692) with cleavage site probability 0.530 between residues 34 and 35
679897000802	1 probable transmembrane helix predicted for HMU01850 by TMHMM2.0 at aa 12-34
679897000803	enolase; Provisional; Region: eno; PRK00077
679897000804	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
679897000805	dimer interface [polypeptide binding]; other site
679897000806	metal binding site [ion binding]; metal-binding site
679897000807	substrate binding pocket [chemical binding]; other site
679897000808	HMMPfam hit to PF00113, Enolase_C, score 2.7e-144
679897000809	HMMPfam hit to PF03952, Enolase_N, score 3e-55
679897000810	recombinase A; Provisional; Region: recA; PRK09354
679897000811	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
679897000812	hexamer interface [polypeptide binding]; other site
679897000813	Walker A motif; other site
679897000814	ATP binding site [chemical binding]; other site
679897000815	Walker B motif; other site
679897000816	HMMPfam hit to PF00154, RecA, score 6e-239
679897000817	PS00321 recA signature.
679897000818	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000819	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
679897000820	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
679897000821	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
679897000822	HMMPfam hit to PF01210, NAD_Gly3P_dh_N, score 1e-21
679897000823	HMMPfam hit to PF07479, NAD_Gly3P_dh_C, score 9.9e-65
679897000824	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
679897000825	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
679897000826	ABC-ATPase subunit  interface; other site
679897000827	dimer interface [polypeptide binding]; other site
679897000828	putative PBP binding regions; other site
679897000829	Signal peptide predicted for HMU01890 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.646 between residues 30 and 31
679897000830	9 probable transmembrane helices predicted for HMU01890 by TMHMM2.0 at aa 5-20, 54-76, 88-107, 112-134, 141-163, 189-211, 232-254, 264-286 and 299-321
679897000831	HMMPfam hit to PF01032, FecCD, score 1.5e-86
679897000832	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000833	PS00044 Bacterial regulatory proteins, lysR family signature.
679897000834	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
679897000835	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
679897000836	Walker A/P-loop; other site
679897000837	ATP binding site [chemical binding]; other site
679897000838	Q-loop/lid; other site
679897000839	ABC transporter signature motif; other site
679897000840	Walker B; other site
679897000841	D-loop; other site
679897000842	H-loop/switch region; other site
679897000843	HMMPfam hit to PF00005, ABC_tran, score 1.2e-39
679897000844	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000845	PS00211 ABC transporters family signature.
679897000846	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
679897000847	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
679897000848	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
679897000849	HMMPfam hit to PF00460, Flg_bb_rod, score 2.4e-11
679897000850	PS00588 Flagella basal body rod proteins signature.
679897000851	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
679897000852	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
679897000853	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
679897000854	protein binding site [polypeptide binding]; other site
679897000855	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
679897000856	protein binding site [polypeptide binding]; other site
679897000857	HMMPfam hit to PF00089, Trypsin, score 1.7e-22
679897000858	HMMPfam hit to PF00595, PDZ, score 6.3e-10
679897000859	flagellar assembly protein FliW; Provisional; Region: PRK13283
679897000860	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
679897000861	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
679897000862	active site
679897000863	HIGH motif; other site
679897000864	nucleotide binding site [chemical binding]; other site
679897000865	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
679897000866	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
679897000867	active site
679897000868	KMSKS motif; other site
679897000869	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
679897000870	tRNA binding surface [nucleotide binding]; other site
679897000871	anticodon binding site; other site
679897000872	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
679897000873	HMMPfam hit to PF00133, tRNA-synt_1, score 2.4e-219
679897000874	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
679897000875	HMMPfam hit to PF08264, Anticodon_1, score 6.5e-32
679897000876	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
679897000877	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897000878	S-adenosylmethionine binding site [chemical binding]; other site
679897000879	HMMPfam hit to PF05175, MTS, score 1.6e-06
679897000880	PS00092 N-6 Adenine-specific DNA methylases signature.
679897000881	Peptidase family M48; Region: Peptidase_M48; pfam01435
679897000882	HMMPfam hit to PF01435, Peptidase_M48, score 8.1e-49
679897000883	7 probable transmembrane helices predicted for HMU01960 by TMHMM2.0 at aa 4-21, 58-80, 95-117, 138-160, 165-187, 284-303 and 318-340
679897000884	CTP synthetase; Validated; Region: pyrG; PRK05380
679897000885	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
679897000886	Catalytic site [active]
679897000887	active site
679897000888	UTP binding site [chemical binding]; other site
679897000889	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
679897000890	active site
679897000891	putative oxyanion hole; other site
679897000892	catalytic triad [active]
679897000893	HMMPfam hit to PF06418, CTP_synth_N, score 3.6e-195
679897000894	HMMPfam hit to PF00117, GATase, score 5.3e-53
679897000895	PS00442 Glutamine amidotransferases class-I active site.
679897000896	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
679897000897	DHH family; Region: DHH; pfam01368
679897000898	DHHA1 domain; Region: DHHA1; pfam02272
679897000899	HMMPfam hit to PF01368, DHH, score 2.7e-42
679897000900	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
679897000901	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
679897000902	active site
679897000903	HMMPfam hit to PF00849, PseudoU_synth_2, score 3e-40
679897000904	PS01129 Rlu family of pseudouridine synthase signature.
679897000905	polyribonucleotide nucleotidyltransferase; Region: polynuc_phos; TIGR03591
679897000906	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
679897000907	HMMPfam hit to PF05136, Phage_portal_2, score 4.2e-09
679897000908	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
679897000909	Uncharacterized conserved protein [Function unknown]; Region: COG3334
679897000910	Signal peptide predicted for HMU02030 by SignalP 2.0 HMM (Signal peptide probability 0.646) with cleavage site probability 0.240 between residues 21 and 22
679897000911	Flagellar FliJ protein; Region: FliJ; pfam02050
679897000912	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
679897000913	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
679897000914	GDP-binding site [chemical binding]; other site
679897000915	ACT binding site; other site
679897000916	IMP binding site; other site
679897000917	HMMPfam hit to PF00709, Adenylsucc_synt, score 1.6e-255
679897000918	PS00513 Adenylosuccinate synthetase active site.
679897000919	PS01266 Adenylosuccinate synthetase GTP-binding site.
679897000920	ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: hisZ; PRK12293
679897000921	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
679897000922	motif 1; other site
679897000923	dimer interface [polypeptide binding]; other site
679897000924	active site
679897000925	motif 2; other site
679897000926	motif 3; other site
679897000927	HMMPfam hit to PF00587, tRNA-synt_2b, score 0.0006
679897000928	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
679897000929	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
679897000930	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
679897000931	active site
679897000932	HMMPfam hit to PF00156, Pribosyltran, score 1.1e-33
679897000933	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
679897000934	PS00114 Phosphoribosyl pyrophosphate synthetase signature.
679897000935	Signal peptide predicted for HMU02080 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.512 between residues 44 and 45
679897000936	Uncharacterized conserved protein [Function unknown]; Region: COG2353
679897000937	HMMPfam hit to PF04264, YceI, score 4.2e-65
679897000938	Signal peptide predicted for HMU02090 by SignalP 2.0 HMM (Signal peptide probability 0.971) with cleavage site probability 0.702 between residues 17 and 18
679897000939	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
679897000940	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
679897000941	active site
679897000942	HIGH motif; other site
679897000943	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
679897000944	active site
679897000945	KMSKS motif; other site
679897000946	HMMPfam hit to PF00749, tRNA-synt_1c, score 2.3e-135
679897000947	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
679897000948	Predicted membrane protein [Function unknown]; Region: COG2860
679897000949	UPF0126 domain; Region: UPF0126; pfam03458
679897000950	UPF0126 domain; Region: UPF0126; pfam03458
679897000951	7 probable transmembrane helices predicted for HMU02110 by TMHMM2.0 at aa 4-26, 33-55, 60-79, 92-114, 118-140, 152-174 and 178-200
679897000952	HMMPfam hit to PF03458, UPF0126, score 1.5e-29
679897000953	HMMPfam hit to PF03458, UPF0126, score 3e-26
679897000954	arginine decarboxylase; Provisional; Region: PRK05354
679897000955	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
679897000956	dimer interface [polypeptide binding]; other site
679897000957	active site
679897000958	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
679897000959	catalytic residues [active]
679897000960	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
679897000961	HMMPfam hit to PF02784, Orn_Arg_deC_N, score 1.1e-29
679897000962	HMMPfam hit to PF00278, Orn_DAP_Arg_deC, score 4.2e-31
679897000963	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
679897000964	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
679897000965	HMMPfam hit to PF05958, tRNA_U5-meth_tr, score 5.3e-95
679897000966	PS01231 RNA methyltransferase trmA family signature 2.
679897000967	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
679897000968	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
679897000969	Na binding site [ion binding]; other site
679897000970	11 probable transmembrane helices predicted for HMU02140 by TMHMM2.0 at aa 10-31, 77-99, 132-154, 161-183, 193-215, 321-343, 367-389, 410-432, 490-512, 519-538 and 542-564
679897000971	HMMPfam hit to PF00474, SSF, score 1.1e-108
679897000972	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897000973	Proline dehydrogenase; Region: Pro_dh; cl03282
679897000974	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
679897000975	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
679897000976	NAD(P) binding site [chemical binding]; other site
679897000977	catalytic residues [active]
679897000978	HMMPfam hit to PF00171, Aldedh, score 2.3e-95
679897000979	PS00070 Aldehyde dehydrogenases cysteine active site.
679897000980	PS00687 Aldehyde dehydrogenases glutamic acid active site.
679897000981	PS00017 ATP/GTP-binding site motif A (P-loop).
679897000982	HMMPfam hit to PF01619, Pro_dh, score 2.7e-94
679897000983	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
679897000984	active site
679897000985	putative catalytic site [active]
679897000986	DNA binding site [nucleotide binding]
679897000987	putative phosphate binding site [ion binding]; other site
679897000988	metal binding site A [ion binding]; metal-binding site
679897000989	AP binding site [nucleotide binding]; other site
679897000990	metal binding site B [ion binding]; metal-binding site
679897000991	HMMPfam hit to PF03372, Exo_endo_phos, score 1.7e-62
679897000992	PS00726 AP endonucleases family 1 signature 1.
679897000993	PS00728 AP endonucleases family 1 signature 3.
679897000994	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
679897000995	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
679897000996	active site
679897000997	phosphorylation site [posttranslational modification]
679897000998	intermolecular recognition site; other site
679897000999	dimerization interface [polypeptide binding]; other site
679897001000	HMMPfam hit to PF00072, Response_reg, score 1.1e-40
679897001001	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
679897001002	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897001003	S-adenosylmethionine binding site [chemical binding]; other site
679897001004	HMMPfam hit to PF06325, PrmA, score 1.3e-41
679897001005	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
679897001006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897001007	Walker A motif; other site
679897001008	ATP binding site [chemical binding]; other site
679897001009	Walker B motif; other site
679897001010	arginine finger; other site
679897001011	Peptidase family M41; Region: Peptidase_M41; pfam01434
679897001012	Signal peptide predicted for HMU02190 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.607 between residues 36 and 37
679897001013	2 probable transmembrane helices predicted for HMU02190 by TMHMM2.0 at aa 15-34 and 117-139
679897001014	HMMPfam hit to PF06480, FtsH_ext, score 9.6e-33
679897001015	HMMPfam hit to PF00004, AAA, score 5.8e-96
679897001016	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001017	PS00674 AAA-protein family signature.
679897001018	HMMPfam hit to PF01434, Peptidase_M41, score 3.2e-109
679897001019	PS00014 Endoplasmic reticulum targeting sequence.
679897001020	Phosphatidylserine decarboxylase; Region: PS_Dcarbxylase; cl03656
679897001021	1 probable transmembrane helix predicted for HMU02200 by TMHMM2.0 at aa 15-48
679897001022	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
679897001023	CDP-diacylglycerol--serine O-phosphatidyltransferase; Region: pssA; TIGR00473
679897001024	6 probable transmembrane helices predicted for HMU02210 by TMHMM2.0 at aa 7-29, 90-112, 125-144, 154-173, 185-202 and 207-229
679897001025	HMMPfam hit to PF01066, CDP-OH_P_transf, score 1.6e-29
679897001026	PS00379 CDP-alcohol phosphatidyltransferases signature.
679897001027	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
679897001028	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
679897001029	metal-binding site [ion binding]
679897001030	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
679897001031	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
679897001032	active site
679897001033	motif I; other site
679897001034	motif II; other site
679897001035	HMMPfam hit to PF00403, HMA, score 5e-10
679897001036	PS01047 Heavy-metal-associated domain.
679897001037	8 probable transmembrane helices predicted for HMU02220 by TMHMM2.0 at aa 90-112, 117-139, 159-181, 186-203, 341-363, 373-395, 676-695 and 699-721
679897001038	HMMPfam hit to PF00122, E1-E2_ATPase, score 1.6e-76
679897001039	HMMPfam hit to PF00702, Hydrolase, score 4.1e-34
679897001040	PS00154 E1-E2 ATPases phosphorylation site.
679897001041	PS01229 Hypothetical cof family signature 2.
679897001042	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
679897001043	metal-binding site [ion binding]
679897001044	HMMPfam hit to PF00403, HMA, score 1.4e-13
679897001045	PS01047 Heavy-metal-associated domain.
679897001046	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
679897001047	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
679897001048	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
679897001049	Walker A/P-loop; other site
679897001050	ATP binding site [chemical binding]; other site
679897001051	Q-loop/lid; other site
679897001052	ABC transporter signature motif; other site
679897001053	Walker B; other site
679897001054	D-loop; other site
679897001055	H-loop/switch region; other site
679897001056	Signal peptide predicted for HMU02240 by SignalP 2.0 HMM (Signal peptide probability 0.872) with cleavage site probability 0.830 between residues 36 and 37
679897001057	5 probable transmembrane helices predicted for HMU02240 by TMHMM2.0 at aa 17-39, 54-76, 145-167, 237-259 and 266-288
679897001058	HMMPfam hit to PF00664, ABC_membrane, score 3.1e-44
679897001059	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897001060	HMMPfam hit to PF00005, ABC_tran, score 2.6e-55
679897001061	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001062	PS00211 ABC transporters family signature.
679897001063	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
679897001064	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
679897001065	dimer interface [polypeptide binding]; other site
679897001066	PYR/PP interface [polypeptide binding]; other site
679897001067	TPP binding site [chemical binding]; other site
679897001068	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
679897001069	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
679897001070	TPP-binding site [chemical binding]; other site
679897001071	dimer interface [polypeptide binding]; other site
679897001072	HMMPfam hit to PF02776, TPP_enzyme_N, score 2.7e-62
679897001073	HMMPfam hit to PF00205, TPP_enzyme_M, score 7e-22
679897001074	HMMPfam hit to PF02775, TPP_enzyme_C, score 6.1e-16
679897001075	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
679897001076	7 probable transmembrane helices predicted for HMU02270 by TMHMM2.0 at aa 35-57, 103-125, 140-162, 198-220, 235-257, 280-302 and 329-351
679897001077	HMMPfam hit to PF03824, NicO, score 1.5e-109
679897001078	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
679897001079	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
679897001080	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
679897001081	active site
679897001082	HIGH motif; other site
679897001083	KMSK motif region; other site
679897001084	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
679897001085	tRNA binding surface [nucleotide binding]; other site
679897001086	anticodon binding site; other site
679897001087	HMMPfam hit to PF05746, DALR_1, score 2.4e-23
679897001088	HMMPfam hit to PF00750, tRNA-synt_1d, score 2e-75
679897001089	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
679897001090	HMMPfam hit to PF03485, Arg_tRNA_synt_N, score 1.9e-18
679897001091	Sec-independent protein secretion pathway components [Intracellular trafficking and secretion]; Region: TatA; COG1826
679897001092	HMMPfam hit to PF02416, MttA_Hcf106, score 1.6e-24
679897001093	1 probable transmembrane helix predicted for HMU02290 by TMHMM2.0 at aa 4-23
679897001094	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
679897001095	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
679897001096	catalytic site [active]
679897001097	G-X2-G-X-G-K; other site
679897001098	HMMPfam hit to PF00625, Guanylate_kin, score 2.1e-35
679897001099	PS00856 Guanylate kinase signature.
679897001100	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001101	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001102	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
679897001103	PLD-like domain; Region: PLDc_2; pfam13091
679897001104	putative active site [active]
679897001105	catalytic site [active]
679897001106	HMMPfam hit to PF00614, PLDc, score 2e-06
679897001107	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
679897001108	trimer interface [polypeptide binding]; other site
679897001109	active site
679897001110	HMMPfam hit to PF00692, dUTPase, score 0.0036
679897001111	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
679897001112	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
679897001113	carboxyltransferase (CT) interaction site; other site
679897001114	biotinylation site [posttranslational modification]; other site
679897001115	HMMPfam hit to PF00364, Biotin_lipoyl, score 2.1e-23
679897001116	biotin carboxylase; Validated; Region: PRK08462
679897001117	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
679897001118	ATP-grasp domain; Region: ATP-grasp_4; cl17255
679897001119	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
679897001120	HMMPfam hit to PF00289, CPSase_L_chain, score 6.9e-41
679897001121	HMMPfam hit to PF02786, CPSase_L_D2, score 1e-111
679897001122	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
679897001123	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
679897001124	HMMPfam hit to PF02785, Biotin_carb_C, score 2.6e-62
679897001125	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
679897001126	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
679897001127	inhibitor-cofactor binding pocket; inhibition site
679897001128	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897001129	catalytic residue [active]
679897001130	HMMPfam hit to PF01041, DegT_DnrJ_EryC1, score 9.7e-119
679897001131	PS00190 Cytochrome c family heme-binding site signature.
679897001132	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
679897001133	Signal peptide predicted for HMU02400 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.275 between residues 22 and 23
679897001134	4 probable transmembrane helices predicted for HMU02400 by TMHMM2.0 at aa 7-26, 41-63, 188-210 and 220-242
679897001135	HMMPfam hit to PF00813, FliP, score 8.7e-113
679897001136	PS01060 Flagella transport protein fliP family signature 1.
679897001137	polyphosphate kinase; Provisional; Region: PRK05443
679897001138	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
679897001139	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
679897001140	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
679897001141	putative domain interface [polypeptide binding]; other site
679897001142	putative active site [active]
679897001143	catalytic site [active]
679897001144	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
679897001145	putative active site [active]
679897001146	catalytic site [active]
679897001147	HMMPfam hit to PF02503, PP_kinase, score 0
679897001148	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14359
679897001149	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
679897001150	Substrate binding site; other site
679897001151	Mg++ binding site; other site
679897001152	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
679897001153	putative trimer interface [polypeptide binding]; other site
679897001154	putative CoA binding site [chemical binding]; other site
679897001155	HMMPfam hit to PF00483, NTP_transferase, score 9.8e-08
679897001156	HMMPfam hit to PF00132, Hexapep, score 86
679897001157	HMMPfam hit to PF00132, Hexapep, score 24
679897001158	HMMPfam hit to PF00132, Hexapep, score 1.4
679897001159	HMMPfam hit to PF00132, Hexapep, score 62
679897001160	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14339
679897001161	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
679897001162	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
679897001163	FeS/SAM binding site; other site
679897001164	HMMPfam hit to PF00919, UPF0004, score 1.3e-27
679897001165	HMMPfam hit to PF04055, Radical_SAM, score 4e-33
679897001166	PS01278 Uncharacterized protein family UPF0004 signature.
679897001167	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
679897001168	putative acyl-acceptor binding pocket; other site
679897001169	1 probable transmembrane helix predicted for HMU02450 by TMHMM2.0 at aa 10-28
679897001170	1 probable transmembrane helix predicted for HMU02470 by TMHMM2.0 at aa 21-43
679897001171	1 probable transmembrane helix predicted for HMU02480 by TMHMM2.0 at aa 20-42
679897001172	Signal peptide predicted for HMU02490 by SignalP 2.0 HMM (Signal peptide probability 0.870) with cleavage site probability 0.598 between residues 18 and 19
679897001173	Flagellin N-methylase; Region: FliB; pfam03692
679897001174	HMMPfam hit to PF03692, UPF0153, score 2.4e-29
679897001175	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
679897001176	Signal peptide predicted for HMU02510 by SignalP 2.0 HMM (Signal peptide probability 0.807) with cleavage site probability 0.598 between residues 20 and 21
679897001177	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
679897001178	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
679897001179	HMMPfam hit to PF00037, Fer4, score 7.4e-05
679897001180	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897001181	HMMPfam hit to PF00037, Fer4, score 0.0044
679897001182	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
679897001183	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
679897001184	nucleotide binding site [chemical binding]; other site
679897001185	HMMPfam hit to PF02541, Ppx-GppA, score 6.2e-79
679897001186	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
679897001187	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
679897001188	HMMPfam hit to PF01075, Glyco_transf_9, score 7.4e-37
679897001189	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
679897001190	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
679897001191	putative acyl-acceptor binding pocket; other site
679897001192	HMMPfam hit to PF03279, Lip_A_acyltrans, score 4.3e-64
679897001193	1 probable transmembrane helix predicted for HMU02550 by TMHMM2.0 at aa 15-37
679897001194	3 probable transmembrane helices predicted for HMU02560 by TMHMM2.0 at aa 28-50, 62-84 and 94-116
679897001195	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
679897001196	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
679897001197	Signal peptide predicted for HMU02570 by SignalP 2.0 HMM (Signal peptide probability 0.985) with cleavage site probability 0.687 between residues 31 and 32
679897001198	9 probable transmembrane helices predicted for HMU02570 by TMHMM2.0 at aa 5-27, 32-54, 69-91, 122-144, 187-209, 222-244, 290-322, 346-368 and 410-432
679897001199	HMMPfam hit to PF02386, TrkH, score 8.7e-70
679897001200	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
679897001201	TrkA-N domain; Region: TrkA_N; pfam02254
679897001202	HMMPfam hit to PF02254, TrkA_N, score 1.5e-28
679897001203	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
679897001204	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
679897001205	active site
679897001206	phosphorylation site [posttranslational modification]
679897001207	intermolecular recognition site; other site
679897001208	dimerization interface [polypeptide binding]; other site
679897001209	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
679897001210	DNA binding site [nucleotide binding]
679897001211	HMMPfam hit to PF00072, Response_reg, score 2.3e-39
679897001212	HMMPfam hit to PF00486, Trans_reg_C, score 4.6e-17
679897001213	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
679897001214	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
679897001215	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
679897001216	dimer interface [polypeptide binding]; other site
679897001217	phosphorylation site [posttranslational modification]
679897001218	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
679897001219	ATP binding site [chemical binding]; other site
679897001220	Mg2+ binding site [ion binding]; other site
679897001221	G-X-G motif; other site
679897001222	1 probable transmembrane helix predicted for HMU02600 by TMHMM2.0 at aa 102-124
679897001223	HMMPfam hit to PF00672, HAMP, score 0.00031
679897001224	HMMPfam hit to PF00512, HisKA, score 0.00023
679897001225	HMMPfam hit to PF02518, HATPase_c, score 3.8e-10
679897001226	FIST N domain; Region: FIST; pfam08495
679897001227	FIST C domain; Region: FIST_C; pfam10442
679897001228	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
679897001229	PAS domain; Region: PAS_9; pfam13426
679897001230	putative active site [active]
679897001231	heme pocket [chemical binding]; other site
679897001232	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
679897001233	PAS domain; Region: PAS_9; pfam13426
679897001234	putative active site [active]
679897001235	heme pocket [chemical binding]; other site
679897001236	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
679897001237	PAS domain; Region: PAS_9; pfam13426
679897001238	putative active site [active]
679897001239	heme pocket [chemical binding]; other site
679897001240	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
679897001241	Zn2+ binding site [ion binding]; other site
679897001242	Mg2+ binding site [ion binding]; other site
679897001243	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897001244	HMMPfam hit to PF08447, PAS_3, score 5.2e-09
679897001245	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001246	HMMPfam hit to PF08447, PAS_3, score 5.2e-09
679897001247	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001248	HMMPfam hit to PF01966, HD, score 3.7e-32
679897001249	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
679897001250	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
679897001251	putative metal binding site; other site
679897001252	HMMPfam hit to PF00535, Glycos_transf_2, score 3.8e-24
679897001253	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
679897001254	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
679897001255	active site
679897001256	Peptidase family U32; Region: Peptidase_U32; pfam01136
679897001257	metal binding site [ion binding]; metal-binding site
679897001258	HMMPfam hit to PF01136, Peptidase_U32, score 9.7e-99
679897001259	PS01276 Peptidase family U32 signature.
679897001260	peptide chain release factor 2; Validated; Region: prfB; PRK00578
679897001261	PCRF domain; Region: PCRF; pfam03462
679897001262	RF-1 domain; Region: RF-1; pfam00472
679897001263	HMMPfam hit to PF00472, RF-1, score 1e-68
679897001264	HMMPfam hit to PF03462, PCRF, score 5.7e-53
679897001265	TMAO/DMSO reductase; Reviewed; Region: PRK05363
679897001266	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
679897001267	Moco binding site; other site
679897001268	metal coordination site [ion binding]; other site
679897001269	HMMPfam hit to PF00174, Oxidored_molyb, score 8.3e-65
679897001270	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
679897001271	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
679897001272	HMMPfam hit to PF03845, Spore_permease, score 0.0014
679897001273	11 probable transmembrane helices predicted for HMU02670 by TMHMM2.0 at aa 9-31, 36-58, 84-106, 126-148, 153-170, 190-212, 233-255, 285-307, 328-345, 355-377 and 389-407
679897001274	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897001275	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001276	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
679897001277	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
679897001278	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
679897001279	HMMPfam hit to PF03315, SDH_beta, score 8e-68
679897001280	HMMPfam hit to PF03313, SDH_alpha, score 1.4e-178
679897001281	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
679897001282	Sel1-like repeats; Region: SEL1; smart00671
679897001283	Sel1-like repeats; Region: SEL1; smart00671
679897001284	Sel1-like repeats; Region: SEL1; smart00671
679897001285	HMMPfam hit to PF08238, Sel1, score 0.0047
679897001286	HMMPfam hit to PF08238, Sel1, score 0.26
679897001287	HMMPfam hit to PF08238, Sel1, score 0.00017
679897001288	HMMPfam hit to PF08238, Sel1, score 0.14
679897001289	Signal peptide predicted for HMU02700 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.966 between residues 23 and 24
679897001290	glycyl-tRNA synthetase subunit alpha; Validated; Region: glyQ; PRK09348
679897001291	motif 1; other site
679897001292	dimer interface [polypeptide binding]; other site
679897001293	active site
679897001294	motif 2; other site
679897001295	motif 3; other site
679897001296	HMMPfam hit to PF02091, tRNA-synt_2e, score 1.5e-207
679897001297	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
679897001298	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897001299	seryl-tRNA synthetase; Provisional; Region: PRK05431
679897001300	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
679897001301	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
679897001302	dimer interface [polypeptide binding]; other site
679897001303	active site
679897001304	motif 1; other site
679897001305	motif 2; other site
679897001306	motif 3; other site
679897001307	HMMPfam hit to PF02403, Seryl_tRNA_N, score 1.4e-20
679897001308	HMMPfam hit to PF00587, tRNA-synt_2b, score 8.5e-59
679897001309	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
679897001310	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
679897001311	binding surface
679897001312	TPR motif; other site
679897001313	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
679897001314	TPR motif; other site
679897001315	1 probable transmembrane helix predicted for HMU02730 by TMHMM2.0 at aa 39-61
679897001316	HMMPfam hit to PF00515, TPR_1, score 0.014
679897001317	HMMPfam hit to PF00515, TPR_1, score 0.074
679897001318	HMMPfam hit to PF00515, TPR_1, score 0.13
679897001319	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
679897001320	Part of AAA domain; Region: AAA_19; pfam13245
679897001321	Family description; Region: UvrD_C_2; pfam13538
679897001322	HMMPfam hit to PF00580, UvrD-helicase, score 4e-168
679897001323	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001324	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK08515
679897001325	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
679897001326	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
679897001327	Flavoprotein; Region: Flavoprotein; pfam02441
679897001328	HMMPfam hit to PF02441, Flavoprotein, score 1.7e-31
679897001329	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
679897001330	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
679897001331	active site
679897001332	(T/H)XGH motif; other site
679897001333	HMMPfam hit to PF01467, CTP_transf_2, score 3.4e-33
679897001334	thymidylate kinase; Validated; Region: tmk; PRK00698
679897001335	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
679897001336	TMP-binding site; other site
679897001337	ATP-binding site [chemical binding]; other site
679897001338	HMMPfam hit to PF02223, Thymidylate_kin, score 1.7e-38
679897001339	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001340	comF family protein; Region: comF; TIGR00201
679897001341	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
679897001342	active site
679897001343	HMMPfam hit to PF00156, Pribosyltran, score 9.8e-06
679897001344	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
679897001345	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
679897001346	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
679897001347	dimer interface [polypeptide binding]; other site
679897001348	ADP-ribose binding site [chemical binding]; other site
679897001349	active site
679897001350	nudix motif; other site
679897001351	metal binding site [ion binding]; metal-binding site
679897001352	HMMPfam hit to PF00293, NUDIX, score 9.1e-22
679897001353	FAD binding domain; Region: FAD_binding_4; pfam01565
679897001354	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
679897001355	HMMPfam hit to PF01565, FAD_binding_4, score 1e-59
679897001356	HMMPfam hit to PF02913, FAD-oxidase_C, score 7.9e-74
679897001357	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
679897001358	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
679897001359	minor groove reading motif; other site
679897001360	helix-hairpin-helix signature motif; other site
679897001361	substrate binding pocket [chemical binding]; other site
679897001362	active site
679897001363	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
679897001364	DNA binding and oxoG recognition site [nucleotide binding]
679897001365	HMMPfam hit to PF00730, HhH-GPD, score 2.4e-12
679897001366	HMMPfam hit to PF00633, HHH, score 2e-06
679897001367	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3399
679897001368	4 probable transmembrane helices predicted for HMU02850 by TMHMM2.0 at aa 10-32, 53-75, 90-110 and 123-140
679897001369	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897001370	prephenate dehydrogenase; Validated; Region: PRK08507
679897001371	Prephenate dehydrogenase; Region: PDH; pfam02153
679897001372	HMMPfam hit to PF02153, PDH, score 3.4e-100
679897001373	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
679897001374	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
679897001375	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
679897001376	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
679897001377	Surface antigen; Region: Bac_surface_Ag; pfam01103
679897001378	HMMPfam hit to PF07244, Surf_Ag_VNR, score 1.1e-08
679897001379	HMMPfam hit to PF07244, Surf_Ag_VNR, score 2e-09
679897001380	HMMPfam hit to PF07244, Surf_Ag_VNR, score 0.00023
679897001381	HMMPfam hit to PF07244, Surf_Ag_VNR, score 8.4e-09
679897001382	HMMPfam hit to PF07244, Surf_Ag_VNR, score 1e-19
679897001383	HMMPfam hit to PF01103, Bac_surface_Ag, score 8e-56
679897001384	PS00107 Protein kinases ATP-binding region signature.
679897001385	hypothetical protein; Provisional; Region: PRK08445
679897001386	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
679897001387	FeS/SAM binding site; other site
679897001388	HMMPfam hit to PF04055, Radical_SAM, score 2.2e-21
679897001389	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
679897001390	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
679897001391	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
679897001392	Signal peptide predicted for HMU02890 by SignalP 2.0 HMM (Signal peptide probability 0.866) with cleavage site probability 0.564 between residues 24 and 25
679897001393	HMMPfam hit to PF00675, Peptidase_M16, score 0.0024
679897001394	HMMPfam hit to PF05193, Peptidase_M16_C, score 1.4e-25
679897001395	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
679897001396	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
679897001397	GatB domain; Region: GatB_Yqey; smart00845
679897001398	HMMPfam hit to PF02934, GatB_N, score 7e-154
679897001399	PS01234 PET112 family signature.
679897001400	HMMPfam hit to PF01162, GatB, score 2.8e-29
679897001401	HMMPfam hit to PF02637, GatB_Yqey, score 2.5e-51
679897001402	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
679897001403	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
679897001404	HMMPfam hit to PF03544, TonB, score 3.1e-06
679897001405	Signal peptide predicted for HMU02910 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.961 between residues 39 and 40
679897001406	1 probable transmembrane helix predicted for HMU02910 by TMHMM2.0 at aa 15-37
679897001407	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
679897001408	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
679897001409	HMMPfam hit to PF02472, ExbD, score 7.5e-45
679897001410	Signal peptide predicted for HMU02920 by SignalP 2.0 HMM (Signal peptide probability 0.963) with cleavage site probability 0.423 between residues 39 and 40
679897001411	1 probable transmembrane helix predicted for HMU02920 by TMHMM2.0 at aa 10-32
679897001412	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
679897001413	HMMPfam hit to PF01618, MotA_ExbB, score 2.1e-40
679897001414	3 probable transmembrane helices predicted for HMU02930 by TMHMM2.0 at aa 10-32, 61-83 and 103-125
679897001415	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
679897001416	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897001417	Walker A motif; other site
679897001418	ATP binding site [chemical binding]; other site
679897001419	Walker B motif; other site
679897001420	arginine finger; other site
679897001421	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
679897001422	HMMPfam hit to PF05362, Lon_C, score 9.1e-101
679897001423	PS01046 ATP-dependent serine proteases, lon family, serine active site.
679897001424	HMMPfam hit to PF00004, AAA, score 1.7e-56
679897001425	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001426	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
679897001427	Signal peptide predicted for HMU02950 by SignalP 2.0 HMM (Signal peptide probability 0.658) with cleavage site probability 0.384 between residues 21 and 22
679897001428	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897001429	flagellar assembly protein FliW; Provisional; Region: PRK13282
679897001430	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
679897001431	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
679897001432	HMMPfam hit to PF03807, F420_oxidored, score 4.9e-31
679897001433	PS00521 Delta 1-pyrroline-5-carboxylate reductase signature.
679897001434	Cache domain; Region: Cache_1; pfam02743
679897001435	5 probable transmembrane helices predicted for HMU02980 by TMHMM2.0 at aa 129-146, 161-183, 204-226, 241-263 and 270-292
679897001436	HMMPfam hit to PF02743, Cache_1, score 1.3e-09
679897001437	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
679897001438	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
679897001439	N-terminal plug; other site
679897001440	ligand-binding site [chemical binding]; other site
679897001441	Signal peptide predicted for HMU02990 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.450 between residues 28 and 29
679897001442	HMMPfam hit to PF07715, Plug, score 3.8e-20
679897001443	HMMPfam hit to PF00593, TonB_dep_Rec, score 2.1e-17
679897001444	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
679897001445	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
679897001446	N-terminal plug; other site
679897001447	ligand-binding site [chemical binding]; other site
679897001448	Signal peptide predicted for HMU03010 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.259 between residues 34 and 35
679897001449	HMMPfam hit to PF07715, Plug, score 3.5e-21
679897001450	HMMPfam hit to PF00593, TonB_dep_Rec, score 6.1e-20
679897001451	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
679897001452	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
679897001453	N-terminal plug; other site
679897001454	ligand-binding site [chemical binding]; other site
679897001455	Signal peptide predicted for HMU03020 by SignalP 2.0 HMM (Signal peptide probability 0.968) with cleavage site probability 0.256 between residues 37 and 38
679897001456	HMMPfam hit to PF07715, Plug, score 4.5e-20
679897001457	HMMPfam hit to PF00593, TonB_dep_Rec, score 2.9e-20
679897001458	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
679897001459	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
679897001460	intersubunit interface [polypeptide binding]; other site
679897001461	Signal peptide predicted for HMU03030 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.749 between residues 20 and 21
679897001462	HMMPfam hit to PF01497, Peripla_BP_2, score 2e-08
679897001463	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
679897001464	active site
679897001465	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
679897001466	HMMPfam hit to PF00535, Glycos_transf_2, score 4e-32
679897001467	urease subunit alpha; Provisional; Region: PRK13986
679897001468	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
679897001469	alpha-gamma subunit interface [polypeptide binding]; other site
679897001470	beta-gamma subunit interface [polypeptide binding]; other site
679897001471	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
679897001472	gamma-beta subunit interface [polypeptide binding]; other site
679897001473	alpha-beta subunit interface [polypeptide binding]; other site
679897001474	HMMPfam hit to PF00547, Urease_gamma, score 1.8e-65
679897001475	HMMPfam hit to PF00699, Urease_beta, score 6.6e-77
679897001476	urease subunit beta; Provisional; Region: ureB; PRK13985
679897001477	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
679897001478	subunit interactions [polypeptide binding]; other site
679897001479	active site
679897001480	flap region; other site
679897001481	HMMPfam hit to PF00449, Urease_alpha, score 2e-82
679897001482	HMMPfam hit to PF01979, Amidohydro_1, score 4.3e-94
679897001483	PS01120 Urease nickel ligands signature.
679897001484	PS00145 Urease active site.
679897001485	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
679897001486	AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293
679897001487	HMMPfam hit to PF02293, AmiS_UreI, score 3.6e-79
679897001488	6 probable transmembrane helices predicted for HMU03070 by TMHMM2.0 at aa 4-23, 30-52, 62-84, 91-113, 117-139 and 146-168
679897001489	Urease accessory protein UreE [Posttranslational modification, protein turnover, chaperones]; Region: UreE; COG2371
679897001490	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
679897001491	dimer interface [polypeptide binding]; other site
679897001492	catalytic residues [active]
679897001493	HMMPfam hit to PF02814, UreE_N, score 3.2e-05
679897001494	HMMPfam hit to PF05194, UreE_C, score 0.0003
679897001495	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
679897001496	UreF; Region: UreF; pfam01730
679897001497	HMMPfam hit to PF01730, UreF, score 1.4e-42
679897001498	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
679897001499	HMMPfam hit to PF02492, cobW, score 1.1e-75
679897001500	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001501	UreD urease accessory protein; Region: UreD; cl00530
679897001502	HMMPfam hit to PF01774, UreD, score 8.3e-45
679897001503	elongation factor Tu; Reviewed; Region: PRK00049
679897001504	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
679897001505	G1 box; other site
679897001506	GEF interaction site [polypeptide binding]; other site
679897001507	GTP/Mg2+ binding site [chemical binding]; other site
679897001508	Switch I region; other site
679897001509	G2 box; other site
679897001510	G3 box; other site
679897001511	Switch II region; other site
679897001512	G4 box; other site
679897001513	G5 box; other site
679897001514	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
679897001515	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
679897001516	Antibiotic Binding Site [chemical binding]; other site
679897001517	HMMPfam hit to PF00009, GTP_EFTU, score 4.7e-97
679897001518	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001519	PS00301 GTP-binding elongation factors signature.
679897001520	HMMPfam hit to PF03144, GTP_EFTU_D2, score 4.3e-26
679897001521	HMMPfam hit to PF03143, GTP_EFTU_D3, score 3.1e-60
679897001522	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
679897001523	HMMPfam hit to PF00584, SecE, score 2.3e-06
679897001524	1 probable transmembrane helix predicted for HMU03130 by TMHMM2.0 at aa 48-70
679897001525	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
679897001526	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
679897001527	putative homodimer interface [polypeptide binding]; other site
679897001528	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
679897001529	heterodimer interface [polypeptide binding]; other site
679897001530	homodimer interface [polypeptide binding]; other site
679897001531	HMMPfam hit to PF02357, NusG, score 6.7e-32
679897001532	PS01014 Transcription termination factor nusG signature.
679897001533	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
679897001534	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
679897001535	23S rRNA interface [nucleotide binding]; other site
679897001536	L7/L12 interface [polypeptide binding]; other site
679897001537	putative thiostrepton binding site; other site
679897001538	L25 interface [polypeptide binding]; other site
679897001539	HMMPfam hit to PF03946, Ribosomal_L11_N, score 2.1e-17
679897001540	HMMPfam hit to PF00298, Ribosomal_L11, score 1.1e-30
679897001541	PS00359 Ribosomal protein L11 signature.
679897001542	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
679897001543	mRNA/rRNA interface [nucleotide binding]; other site
679897001544	HMMPfam hit to PF00687, Ribosomal_L1, score 1.7e-116
679897001545	PS01199 Ribosomal protein L1 signature.
679897001546	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
679897001547	23S rRNA interface [nucleotide binding]; other site
679897001548	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
679897001549	HMMPfam hit to PF00466, Ribosomal_L10, score 3e-19
679897001550	PS01109 Ribosomal protein L10 signature.
679897001551	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
679897001552	L11 interface [polypeptide binding]; other site
679897001553	putative EF-Tu interaction site [polypeptide binding]; other site
679897001554	putative EF-G interaction site [polypeptide binding]; other site
679897001555	HMMPfam hit to PF00542, Ribosomal_L12, score 8.6e-40
679897001556	bifunctional DNA-directed RNA polymerase subunit beta/beta'; Reviewed; Region: PRK09603
679897001557	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
679897001558	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
679897001559	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
679897001560	RPB11 interaction site [polypeptide binding]; other site
679897001561	RPB12 interaction site [polypeptide binding]; other site
679897001562	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
679897001563	RPB3 interaction site [polypeptide binding]; other site
679897001564	RPB1 interaction site [polypeptide binding]; other site
679897001565	RPB11 interaction site [polypeptide binding]; other site
679897001566	RPB10 interaction site [polypeptide binding]; other site
679897001567	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
679897001568	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
679897001569	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
679897001570	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
679897001571	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
679897001572	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
679897001573	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
679897001574	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
679897001575	DNA binding site [nucleotide binding]
679897001576	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
679897001577	HMMPfam hit to PF04563, RNA_pol_Rpb2_1, score 6.8e-21
679897001578	HMMPfam hit to PF04561, RNA_pol_Rpb2_2, score 2.4e-18
679897001579	HMMPfam hit to PF04565, RNA_pol_Rpb2_3, score 6.9e-43
679897001580	HMMPfam hit to PF00562, RNA_pol_Rpb2_6, score 3.7e-164
679897001581	PS01166 RNA polymerases beta chain signature.
679897001582	HMMPfam hit to PF04560, RNA_pol_Rpb2_7, score 5.6e-49
679897001583	HMMPfam hit to PF04997, RNA_pol_Rpb1_1, score 6.9e-139
679897001584	HMMPfam hit to PF00623, RNA_pol_Rpb1_2, score 4.1e-80
679897001585	HMMPfam hit to PF04983, RNA_pol_Rpb1_3, score 1.5e-44
679897001586	HMMPfam hit to PF05000, RNA_pol_Rpb1_4, score 2.2e-30
679897001587	HMMPfam hit to PF04998, RNA_pol_Rpb1_5, score 3.4e-81
679897001588	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001589	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
679897001590	S17 interaction site [polypeptide binding]; other site
679897001591	S8 interaction site; other site
679897001592	16S rRNA interaction site [nucleotide binding]; other site
679897001593	streptomycin interaction site [chemical binding]; other site
679897001594	23S rRNA interaction site [nucleotide binding]; other site
679897001595	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
679897001596	HMMPfam hit to PF00164, Ribosomal_S12, score 1.8e-72
679897001597	PS00055 Ribosomal protein S12 signature.
679897001598	30S ribosomal protein S7; Validated; Region: PRK05302
679897001599	HMMPfam hit to PF00177, Ribosomal_S7, score 1.2e-75
679897001600	PS00052 Ribosomal protein S7 signature.
679897001601	elongation factor G; Reviewed; Region: PRK00007
679897001602	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
679897001603	G1 box; other site
679897001604	putative GEF interaction site [polypeptide binding]; other site
679897001605	GTP/Mg2+ binding site [chemical binding]; other site
679897001606	Switch I region; other site
679897001607	G2 box; other site
679897001608	G3 box; other site
679897001609	Switch II region; other site
679897001610	G4 box; other site
679897001611	G5 box; other site
679897001612	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
679897001613	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
679897001614	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
679897001615	HMMPfam hit to PF00009, GTP_EFTU, score 4.2e-116
679897001616	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001617	PS00301 GTP-binding elongation factors signature.
679897001618	HMMPfam hit to PF03144, GTP_EFTU_D2, score 3.6e-17
679897001619	PS00226 Intermediate filaments signature.
679897001620	HMMPfam hit to PF03764, EFG_IV, score 3.7e-70
679897001621	HMMPfam hit to PF00679, EFG_C, score 2.7e-52
679897001622	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
679897001623	active site
679897001624	zinc binding site [ion binding]; other site
679897001625	HMMPfam hit to PF00194, Carb_anhydrase, score 9.8e-26
679897001626	HMMPfam hit to PF01856, HP_OMP, score 0.0033
679897001627	Signal peptide predicted for HMU03240 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.683 between residues 16 and 17
679897001628	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
679897001629	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
679897001630	FMN binding site [chemical binding]; other site
679897001631	active site
679897001632	catalytic residues [active]
679897001633	substrate binding site [chemical binding]; other site
679897001634	HMMPfam hit to PF01207, Dus, score 2.2e-78
679897001635	PS00435 Peroxidases proximal heme-ligand signature.
679897001636	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
679897001637	Ligand Binding Site [chemical binding]; other site
679897001638	HMMPfam hit to PF06508, ExsB, score 3.5e-82
679897001639	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
679897001640	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
679897001641	active site
679897001642	NTP binding site [chemical binding]; other site
679897001643	metal binding triad [ion binding]; metal-binding site
679897001644	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
679897001645	HMMPfam hit to PF01743, PolyA_pol, score 3.8e-42
679897001646	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897001647	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3787; cl17897
679897001648	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
679897001649	PhnA protein; Region: PhnA; pfam03831
679897001650	HMMPfam hit to PF03831, PhnA, score 1.2e-27
679897001651	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
679897001652	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
679897001653	dimer interface [polypeptide binding]; other site
679897001654	decamer (pentamer of dimers) interface [polypeptide binding]; other site
679897001655	catalytic triad [active]
679897001656	peroxidatic and resolving cysteines [active]
679897001657	HMMPfam hit to PF00578, AhpC-TSA, score 1.2e-43
679897001658	S-adenosylmethionine synthetase; Validated; Region: PRK05250
679897001659	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
679897001660	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
679897001661	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
679897001662	HMMPfam hit to PF00438, S-AdoMet_synt_N, score 5.7e-49
679897001663	HMMPfam hit to PF02772, S-AdoMet_synt_M, score 3e-67
679897001664	PS00376 S-adenosylmethionine synthetase signature 1.
679897001665	HMMPfam hit to PF02773, S-AdoMet_synt_C, score 2.7e-82
679897001666	PS00377 S-adenosylmethionine synthetase signature 2.
679897001667	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
679897001668	HMMPfam hit to PF00037, Fer4, score 6.1e-06
679897001669	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897001670	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
679897001671	HMMPfam hit to PF01245, Ribosomal_L19, score 9.1e-65
679897001672	PS01015 Ribosomal protein L19 signature.
679897001673	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
679897001674	HMMPfam hit to PF01746, tRNA_m1G_MT, score 1.3e-32
679897001675	RimM protein, required for 16S rRNA processing [Translation, ribosomal structure and biogenesis]; Region: RimM; COG0806
679897001676	RimM N-terminal domain; Region: RimM; pfam01782
679897001677	PRC-barrel domain; Region: PRC; pfam05239
679897001678	HMMPfam hit to PF05239, PRC, score 1.5e-05
679897001679	HMMPfam hit to PF01782, RimM, score 3.9e-07
679897001680	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
679897001681	KH domain; Region: KH_4; pfam13083
679897001682	G-X-X-G motif; other site
679897001683	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
679897001684	HMMPfam hit to PF00886, Ribosomal_S16, score 4e-33
679897001685	PS00732 Ribosomal protein S16 signature.
679897001686	signal recognition particle protein; Provisional; Region: PRK10867
679897001687	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
679897001688	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
679897001689	P loop; other site
679897001690	GTP binding site [chemical binding]; other site
679897001691	Signal peptide binding domain; Region: SRP_SPB; pfam02978
679897001692	HMMPfam hit to PF02978, SRP_SPB, score 7.5e-51
679897001693	HMMPfam hit to PF00448, SRP54, score 1.5e-105
679897001694	PS00300 SRP54-type proteins GTP-binding domain signature.
679897001695	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001696	HMMPfam hit to PF02881, SRP54_N, score 1.1e-10
679897001697	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
679897001698	metal binding site 2 [ion binding]; metal-binding site
679897001699	putative DNA binding helix; other site
679897001700	metal binding site 1 [ion binding]; metal-binding site
679897001701	dimer interface [polypeptide binding]; other site
679897001702	structural Zn2+ binding site [ion binding]; other site
679897001703	HMMPfam hit to PF01475, FUR, score 9.5e-21
679897001704	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
679897001705	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
679897001706	active site
679897001707	PS00237 G-protein coupled receptors signature.
679897001708	HMMPfam hit to PF01569, PAP2, score 1.7e-20
679897001709	2 probable transmembrane helices predicted for HMU03420 by TMHMM2.0 at aa 120-142 and 152-169
679897001710	Signal peptide predicted for HMU03420 by SignalP 2.0 HMM (Signal peptide probability 0.815) with cleavage site probability 0.565 between residues 26 and 27
679897001711	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
679897001712	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
679897001713	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897001714	HMMPfam hit to PF02119, FlgI, score 5e-153
679897001715	flagellar rod assembly protein/muramidase FlgJ; Region: flagell_FlgJ; TIGR02541
679897001716	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
679897001717	dimer interface [polypeptide binding]; other site
679897001718	phosphorylation site [posttranslational modification]
679897001719	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
679897001720	ATP binding site [chemical binding]; other site
679897001721	Mg2+ binding site [ion binding]; other site
679897001722	G-X-G motif; other site
679897001723	HMMPfam hit to PF00512, HisKA, score 3.2e-09
679897001724	HMMPfam hit to PF02518, HATPase_c, score 1.4e-22
679897001725	glutamate dehydrogenase; Provisional; Region: PRK09414
679897001726	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
679897001727	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
679897001728	NAD(P) binding site [chemical binding]; other site
679897001729	HMMPfam hit to PF02812, ELFV_dehydrog_N, score 1.7e-74
679897001730	PS00074 Glu / Leu / Phe / Val dehydrogenases active site.
679897001731	HMMPfam hit to PF00208, ELFV_dehydrog, score 3.4e-135
679897001732	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
679897001733	dimer interface [polypeptide binding]; other site
679897001734	conserved gate region; other site
679897001735	putative PBP binding loops; other site
679897001736	ABC-ATPase subunit interface; other site
679897001737	HMMPfam hit to PF00528, BPD_transp_1, score 1.8e-25
679897001738	5 probable transmembrane helices predicted for HMU03470 by TMHMM2.0 at aa 25-46, 66-83, 87-104, 132-154 and 188-210
679897001739	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
679897001740	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
679897001741	HMMPfam hit to PF00528, BPD_transp_1, score 1.6e-11
679897001742	4 probable transmembrane helices predicted for HMU03480 by TMHMM2.0 at aa 20-42, 62-84, 157-176 and 186-208
679897001743	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
679897001744	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
679897001745	Walker A/P-loop; other site
679897001746	ATP binding site [chemical binding]; other site
679897001747	Q-loop/lid; other site
679897001748	ABC transporter signature motif; other site
679897001749	Walker B; other site
679897001750	D-loop; other site
679897001751	H-loop/switch region; other site
679897001752	HMMPfam hit to PF00005, ABC_tran, score 3.6e-65
679897001753	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001754	PS00211 ABC transporters family signature.
679897001755	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
679897001756	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
679897001757	substrate binding pocket [chemical binding]; other site
679897001758	membrane-bound complex binding site; other site
679897001759	hinge residues; other site
679897001760	Signal peptide predicted for HMU03500 by SignalP 2.0 HMM (Signal peptide probability 0.907) with cleavage site probability 0.388 between residues 20 and 21
679897001761	HMMPfam hit to PF00497, SBP_bac_3, score 1.2e-52
679897001762	Signal peptide predicted for HMU03510 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.408 between residues 25 and 26
679897001763	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
679897001764	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
679897001765	HMMPfam hit to PF01977, UbiD, score 2.7e-160
679897001766	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
679897001767	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
679897001768	catalytic residue [active]
679897001769	HMMPfam hit to PF01168, Ala_racemase_N, score 3.4e-07
679897001770	PS01211 Uncharacterized protein family UPF0001 signature.
679897001771	Protein of unknown function DUF89; Region: DUF89; cl15397
679897001772	Protein of unknown function (DUF3972); Region: DUF3972; pfam13118
679897001773	flagellar motor protein MotB; Reviewed; Region: motB; PRK08457
679897001774	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
679897001775	ligand binding site [chemical binding]; other site
679897001776	HMMPfam hit to PF00691, OmpA, score 5.9e-17
679897001777	1 probable transmembrane helix predicted for HMU03570 by TMHMM2.0 at aa 17-39
679897001778	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cd00596
679897001779	active site
679897001780	Zn binding site [ion binding]; other site
679897001781	glutamylglutaminyl-tRNA synthetase; Provisional; Region: PRK12410
679897001782	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
679897001783	active site
679897001784	HIGH motif; other site
679897001785	nucleotide binding site [chemical binding]; other site
679897001786	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
679897001787	active site
679897001788	KMSKS motif; other site
679897001789	HMMPfam hit to PF00749, tRNA-synt_1c, score 1.4e-81
679897001790	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
679897001791	YGGT family; Region: YGGT; pfam02325
679897001792	HMMPfam hit to PF02325, YGGT, score 2.1e-09
679897001793	2 probable transmembrane helices predicted for HMU03620 by TMHMM2.0 at aa 2-24 and 54-76
679897001794	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
679897001795	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
679897001796	N-acetyl-D-glucosamine binding site [chemical binding]; other site
679897001797	catalytic residue [active]
679897001798	HMMPfam hit to PF01464, SLT, score 8.3e-21
679897001799	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
679897001800	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
679897001801	active site
679897001802	tetramer interface; other site
679897001803	HMMPfam hit to PF00483, NTP_transferase, score 1.5e-23
679897001804	Signal peptide predicted for HMU03650 by SignalP 2.0 HMM (Signal peptide probability 0.862) with cleavage site probability 0.637 between residues 38 and 39
679897001805	1 probable transmembrane helix predicted for HMU03650 by TMHMM2.0 at aa 6-28
679897001806	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
679897001807	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
679897001808	hinge; other site
679897001809	active site
679897001810	HMMPfam hit to PF00275, EPSP_synthase, score 3.3e-105
679897001811	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
679897001812	Aspartase; Region: Aspartase; cd01357
679897001813	active sites [active]
679897001814	tetramer interface [polypeptide binding]; other site
679897001815	HMMPfam hit to PF00206, Lyase_1, score 7.5e-149
679897001816	PS00163 Fumarate lyases signature.
679897001817	Uncharacterized subfamily of Uracil-DNA glycosylases; Region: UDG_like_2; cd10034
679897001818	putative uracil binding site [chemical binding]; other site
679897001819	putative active site [active]
679897001820	DDE superfamily endonuclease; Region: DDE_5; cl17874
679897001821	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
679897001822	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
679897001823	Phosphate transporter family; Region: PHO4; pfam01384
679897001824	Phosphate transporter family; Region: PHO4; cl00396
679897001825	Signal peptide predicted for HMU03700 by SignalP 2.0 HMM (Signal peptide probability 0.983) with cleavage site probability 0.293 between residues 37 and 38
679897001826	12 probable transmembrane helices predicted for HMU03700 by TMHMM2.0 at aa 15-33, 40-62, 77-99, 120-142, 177-199, 212-234, 244-263, 284-302, 333-355, 368-390, 394-411 and 489-511
679897001827	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897001828	HMMPfam hit to PF01384, PHO4, score 4.8e-145
679897001829	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
679897001830	Domain of unknown function DUF21; Region: DUF21; pfam01595
679897001831	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
679897001832	Transporter associated domain; Region: CorC_HlyC; smart01091
679897001833	Signal peptide predicted for HMU03710 by SignalP 2.0 HMM (Signal peptide probability 0.906) with cleavage site probability 0.765 between residues 29 and 30
679897001834	4 probable transmembrane helices predicted for HMU03710 by TMHMM2.0 at aa 4-26, 72-94, 104-126 and 139-161
679897001835	HMMPfam hit to PF00571, CBS, score 4.8e-27
679897001836	HMMPfam hit to PF03471, CorC_HlyC, score 1.1e-21
679897001837	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
679897001838	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
679897001839	active site residue [active]
679897001840	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
679897001841	Walker A/P-loop; other site
679897001842	ATP binding site [chemical binding]; other site
679897001843	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001844	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897001845	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
679897001846	Sulfatase; Region: Sulfatase; pfam00884
679897001847	HMMPfam hit to PF00884, Sulfatase, score 4e-37
679897001848	5 probable transmembrane helices predicted for HMU03730 by TMHMM2.0 at aa 13-35, 55-74, 79-101, 135-157 and 164-186
679897001849	Signal peptide predicted for HMU03730 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.511 between residues 26 and 27
679897001850	6 probable transmembrane helices predicted for HMU03740 by TMHMM2.0 at aa 25-47, 52-71, 83-105, 109-131, 136-155 and 159-176
679897001851	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897001852	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
679897001853	BNR repeat-like domain; Region: BNR_2; pfam13088
679897001854	PS00120 Lipases, serine active site.
679897001855	Signal peptide predicted for HMU03750 by SignalP 2.0 HMM (Signal peptide probability 0.979) with cleavage site probability 0.244 between residues 36 and 37
679897001856	1 probable transmembrane helix predicted for HMU03750 by TMHMM2.0 at aa 3-22
679897001857	PS00443 Glutamine amidotransferases class-II active site.
679897001858	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
679897001859	putative CheA interaction surface; other site
679897001860	HMMPfam hit to PF01584, CheW, score 4e-22
679897001861	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
679897001862	putative binding surface; other site
679897001863	active site
679897001864	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
679897001865	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
679897001866	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
679897001867	ATP binding site [chemical binding]; other site
679897001868	Mg2+ binding site [ion binding]; other site
679897001869	G-X-G motif; other site
679897001870	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
679897001871	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
679897001872	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
679897001873	active site
679897001874	phosphorylation site [posttranslational modification]
679897001875	intermolecular recognition site; other site
679897001876	dimerization interface [polypeptide binding]; other site
679897001877	HMMPfam hit to PF00072, Response_reg, score 1.5e-29
679897001878	PS00217 Sugar transport proteins signature 2.
679897001879	HMMPfam hit to PF01584, CheW, score 2.3e-29
679897001880	HMMPfam hit to PF02518, HATPase_c, score 9.2e-28
679897001881	HMMPfam hit to PF02895, H-kinase_dim, score 2.5e-27
679897001882	HMMPfam hit to PF01627, Hpt, score 4e-14
679897001883	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
679897001884	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
679897001885	putative active site [active]
679897001886	putative metal binding site [ion binding]; other site
679897001887	HMMPfam hit to PF00149, Metallophos, score 0.0002
679897001888	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
679897001889	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
679897001890	HMMPfam hit to PF02774, Semialdhyde_dhC, score 2.4e-09
679897001891	PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site.
679897001892	HMMPfam hit to PF01118, Semialdhyde_dh, score 3.4e-38
679897001893	Domain of unknown function (DUF4149); Region: DUF4149; pfam13664
679897001894	4 probable transmembrane helices predicted for HMU03800 by TMHMM2.0 at aa 13-35, 55-77, 90-112 and 141-160
679897001895	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897001896	Protein of unknown function (DUF328); Region: DUF328; cl01143
679897001897	flagellar protein FliS; Validated; Region: fliS; PRK05685
679897001898	HMMPfam hit to PF02561, FliS, score 2e-49
679897001899	flagellar capping protein; Validated; Region: fliD; PRK08453
679897001900	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
679897001901	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
679897001902	HMMPfam hit to PF07195, FliD_C, score 1.3e-54
679897001903	PS00152 ATP synthase alpha and beta subunits signature.
679897001904	HMMPfam hit to PF07196, Flagellin_IN, score 9.8e-10
679897001905	HMMPfam hit to PF02465, FliD_N, score 2.3e-22
679897001906	flagellar protein FlaG; Provisional; Region: PRK08452
679897001907	HMMPfam hit to PF03646, FlaG, score 6.6e-20
679897001908	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
679897001909	Peptidase family M23; Region: Peptidase_M23; pfam01551
679897001910	HMMPfam hit to PF01551, Peptidase_M23, score 2.6e-17
679897001911	4 probable transmembrane helices predicted for HMU03870 by TMHMM2.0 at aa 10-27, 148-170, 195-217 and 244-266
679897001912	Signal peptide predicted for HMU03870 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.364 between residues 30 and 31
679897001913	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
679897001914	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
679897001915	Walker A/P-loop; other site
679897001916	ATP binding site [chemical binding]; other site
679897001917	Q-loop/lid; other site
679897001918	ABC transporter signature motif; other site
679897001919	Walker B; other site
679897001920	D-loop; other site
679897001921	H-loop/switch region; other site
679897001922	HMMPfam hit to PF00005, ABC_tran, score 2.4e-43
679897001923	PS00211 ABC transporters family signature.
679897001924	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001925	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897001926	S-adenosylmethionine binding site [chemical binding]; other site
679897001927	HMMPfam hit to PF02390, Methyltransf_4, score 1.8e-46
679897001928	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
679897001929	Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401
679897001930	Interdomain contacts; other site
679897001931	Cytokine receptor motif; other site
679897001932	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
679897001933	Interdomain contacts; other site
679897001934	Cytokine receptor motif; other site
679897001935	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
679897001936	Interdomain contacts; other site
679897001937	HMMPfam hit to PF00041, fn3, score 0.0079
679897001938	HMMPfam hit to PF00041, fn3, score 0.0027
679897001939	HMMPfam hit to PF00041, fn3, score 0.0098
679897001940	HMMPfam hit to PF00041, fn3, score 0.002
679897001941	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
679897001942	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
679897001943	RNA binding surface [nucleotide binding]; other site
679897001944	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
679897001945	active site
679897001946	HMMPfam hit to PF00849, PseudoU_synth_2, score 6.9e-50
679897001947	HMMPfam hit to PF01479, S4, score 2.1e-06
679897001948	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
679897001949	Signal peptide predicted for HMU03920 by SignalP 2.0 HMM (Signal peptide probability 0.688) with cleavage site probability 0.551 between residues 35 and 36
679897001950	HMMPfam hit to PF01098, FTSW_RODA_SPOVE, score 3.3e-77
679897001951	9 probable transmembrane helices predicted for HMU03920 by TMHMM2.0 at aa 10-32, 45-62, 72-94, 160-179, 183-205, 251-268, 272-294, 301-323 and 333-355
679897001952	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
679897001953	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
679897001954	active site
679897001955	oxyanion hole [active]
679897001956	catalytic triad [active]
679897001957	HMMPfam hit to PF00657, Lipase_GDSL, score 3.6e-08
679897001958	SGNH_peri2; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri2; cd01829
679897001959	active site
679897001960	catalytic triad [active]
679897001961	oxyanion hole [active]
679897001962	1 probable transmembrane helix predicted for HMU03940 by TMHMM2.0 at aa 3-25
679897001963	Signal peptide predicted for HMU03940 by SignalP 2.0 HMM (Signal peptide probability 0.747) with cleavage site probability 0.366 between residues 23 and 24
679897001964	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
679897001965	12 probable transmembrane helices predicted for HMU03950 by TMHMM2.0 at aa 3-22, 37-59, 72-89, 115-137, 150-169, 184-202, 245-267, 306-323, 330-347, 367-389, 402-419 and 439-461
679897001966	HMMPfam hit to PF03062, MBOAT, score 1.6e-57
679897001967	1 probable transmembrane helix predicted for HMU03960 by TMHMM2.0 at aa 23-45
679897001968	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897001969	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
679897001970	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
679897001971	generic binding surface II; other site
679897001972	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
679897001973	ATP binding site [chemical binding]; other site
679897001974	putative Mg++ binding site [ion binding]; other site
679897001975	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
679897001976	nucleotide binding region [chemical binding]; other site
679897001977	ATP-binding site [chemical binding]; other site
679897001978	HMMPfam hit to PF00271, Helicase_C, score 2.5e-11
679897001979	HMMPfam hit to PF00270, DEAD, score 5.9e-22
679897001980	PS00017 ATP/GTP-binding site motif A (P-loop).
679897001981	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
679897001982	HMMPfam hit to PF01227, GTP_cyclohydroI, score 3.8e-47
679897001983	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
679897001984	oligomerisation interface [polypeptide binding]; other site
679897001985	mobile loop; other site
679897001986	HMMPfam hit to PF00166, Cpn10, score 4e-34
679897001987	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
679897001988	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
679897001989	ring oligomerisation interface [polypeptide binding]; other site
679897001990	ATP/Mg binding site [chemical binding]; other site
679897001991	stacking interactions; other site
679897001992	hinge regions; other site
679897001993	HMMPfam hit to PF00118, Cpn60_TCP1, score 2.1e-192
679897001994	PS00296 Chaperonins cpn60 signature.
679897001995	3 probable transmembrane helices predicted for HMU04010 by TMHMM2.0 at aa 44-63, 73-95 and 116-138
679897001996	1 probable transmembrane helix predicted for HMU04020 by TMHMM2.0 at aa 4-22
679897001997	PS00294 Prenyl group binding site (CAAX box).
679897001998	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
679897001999	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
679897002000	iron-sulfur cluster [ion binding]; other site
679897002001	[2Fe-2S] cluster binding site [ion binding]; other site
679897002002	Signal peptide predicted for HMU04030 by SignalP 2.0 HMM (Signal peptide probability 0.914) with cleavage site probability 0.420 between residues 28 and 29
679897002003	1 probable transmembrane helix predicted for HMU04030 by TMHMM2.0 at aa 9-28
679897002004	HMMPfam hit to PF00355, Rieske, score 3e-11
679897002005	PS00199 Rieske iron-sulfur protein signature 1.
679897002006	PS00200 Rieske iron-sulfur protein signature 2.
679897002007	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
679897002008	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
679897002009	intrachain domain interface; other site
679897002010	interchain domain interface [polypeptide binding]; other site
679897002011	heme bH binding site [chemical binding]; other site
679897002012	Qi binding site; other site
679897002013	heme bL binding site [chemical binding]; other site
679897002014	Qo binding site; other site
679897002015	interchain domain interface [polypeptide binding]; other site
679897002016	intrachain domain interface; other site
679897002017	Qi binding site; other site
679897002018	Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032
679897002019	Qo binding site; other site
679897002020	HMMPfam hit to PF00033, Cytochrom_B_N, score 2.1e-65
679897002021	9 probable transmembrane helices predicted for HMU04040 by TMHMM2.0 at aa 37-59, 96-118, 125-147, 151-170, 191-213, 258-280, 314-336, 351-373 and 380-402
679897002022	HMMPfam hit to PF00032, Cytochrom_B_C, score 1.1e-08
679897002023	PS00193 Cytochrome b/b6 Qo site signature.
679897002024	Cytochrome c1 [Energy production and conversion]; Region: CYT1; COG2857
679897002025	Cytochrome c; Region: Cytochrom_C; pfam00034
679897002026	PS00228 Tubulin-beta mRNA autoregulation signal.
679897002027	2 probable transmembrane helices predicted for HMU04050 by TMHMM2.0 at aa 7-29 and 276-295
679897002028	PS00190 Cytochrome c family heme-binding site signature.
679897002029	HMMPfam hit to PF00034, Cytochrom_C, score 0.00026
679897002030	Monomeric isocitrate dehydrogenase [Energy production and conversion]; Region: Icd; COG2838
679897002031	Monomeric isocitrate dehydrogenase; Region: IDH; cl15383
679897002032	HMMPfam hit to PF03971, IDH, score 0
679897002033	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
679897002034	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
679897002035	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
679897002036	HMMPfam hit to PF01420, Methylase_S, score 2.6e-15
679897002037	HMMPfam hit to PF01420, Methylase_S, score 8.5e-24
679897002038	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK14607
679897002039	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
679897002040	glutamine binding [chemical binding]; other site
679897002041	catalytic triad [active]
679897002042	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
679897002043	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
679897002044	HMMPfam hit to PF00591, Glycos_transf_3, score 4e-86
679897002045	HMMPfam hit to PF02885, Glycos_trans_3N, score 1.3e-10
679897002046	HMMPfam hit to PF00117, GATase, score 1.3e-72
679897002047	PS00442 Glutamine amidotransferases class-I active site.
679897002048	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
679897002049	anthranilate synthase component I, non-proteobacterial lineages; Region: trpE_most; TIGR00564
679897002050	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
679897002051	HMMPfam hit to PF00425, Chorismate_bind, score 9.6e-131
679897002052	HMMPfam hit to PF04715, Anth_synt_I_N, score 7.3e-21
679897002053	PS00030 Eukaryotic  RNA-binding region RNP-1 signature.
679897002054	Outer membrane efflux protein; Region: OEP; pfam02321
679897002055	Outer membrane efflux protein; Region: OEP; pfam02321
679897002056	Signal peptide predicted for HMU04120 by SignalP 2.0 HMM (Signal peptide probability 0.986) with cleavage site probability 0.938 between residues 18 and 19
679897002057	HMMPfam hit to PF02321, OEP, score 7e-11
679897002058	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
679897002059	HlyD family secretion protein; Region: HlyD_3; pfam13437
679897002060	AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873
679897002061	HMMPfam hit to PF00873, ACR_tran, score 0
679897002062	Signal peptide predicted for HMU04140 by SignalP 2.0 HMM (Signal peptide probability 0.909) with cleavage site probability 0.389 between residues 29 and 30
679897002063	12 probable transmembrane helices predicted for HMU04140 by TMHMM2.0 at aa 13-35, 326-345, 350-369, 379-401, 422-444, 459-481, 510-532, 847-869, 876-893, 903-925, 952-974 and 984-1006
679897002064	PS00017 ATP/GTP-binding site motif A (P-loop).
679897002065	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
679897002066	HMMPfam hit to PF01856, HP_OMP, score 1.8e-11
679897002067	heme oxygenase, HugZ family; Region: heme_ox_HugZ; TIGR04109
679897002068	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
679897002069	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
679897002070	HMMPfam hit to PF01243, Pyridox_oxidase, score 2e-18
679897002071	carbon starvation protein A; Provisional; Region: PRK15015
679897002072	Carbon starvation protein CstA; Region: CstA; pfam02554
679897002073	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
679897002074	Signal peptide predicted for HMU04190 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.440 between residues 25 and 26
679897002075	16 probable transmembrane helices predicted for HMU04190 by TMHMM2.0 at aa 5-24, 29-51, 83-105, 115-137, 158-180, 190-207, 214-236, 251-273, 280-302, 317-339, 360-382, 461-483, 504-526, 541-563, 570-589 and 634-656
679897002076	HMMPfam hit to PF02554, CstA, score 8.8e-245
679897002077	PS00107 Protein kinases ATP-binding region signature.
679897002078	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002079	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
679897002080	RuvA N terminal domain; Region: RuvA_N; pfam01330
679897002081	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
679897002082	HMMPfam hit to PF07499, RuvA_C, score 4.3e-08
679897002083	HMMPfam hit to PF01330, RuvA_N, score 9.8e-18
679897002084	Protein of unknown function (DUF342); Region: DUF342; pfam03961
679897002085	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
679897002086	12 probable transmembrane helices predicted for HMU04220 by TMHMM2.0 at aa 25-44, 78-100, 120-142, 147-169, 179-201, 255-277, 281-300, 321-343, 363-385, 392-414, 419-441 and 453-475
679897002087	HMMPfam hit to PF03023, MVIN, score 2.2e-94
679897002088	PS00030 Eukaryotic  RNA-binding region RNP-1 signature.
679897002089	Class I aldolases; Region: Aldolase_Class_I; cl17187
679897002090	transaldolase; Provisional; Region: PRK03903
679897002091	catalytic residue [active]
679897002092	HMMPfam hit to PF00923, Transaldolase, score 5.5e-35
679897002093	PS01054 Transaldolase signature 1.
679897002094	Signal peptide predicted for HMU04240 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.835 between residues 22 and 23
679897002095	GTPase CgtA; Reviewed; Region: obgE; PRK12299
679897002096	GTP1/OBG; Region: GTP1_OBG; pfam01018
679897002097	Obg GTPase; Region: Obg; cd01898
679897002098	G1 box; other site
679897002099	GTP/Mg2+ binding site [chemical binding]; other site
679897002100	Switch I region; other site
679897002101	G2 box; other site
679897002102	G3 box; other site
679897002103	Switch II region; other site
679897002104	G4 box; other site
679897002105	G5 box; other site
679897002106	HMMPfam hit to PF01018, GTP1_OBG, score 1.8e-83
679897002107	HMMPfam hit to PF01926, MMR_HSR1, score 1.5e-38
679897002108	PS00017 ATP/GTP-binding site motif A (P-loop).
679897002109	PS00905 GTP1/OBG family signature.
679897002110	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
679897002111	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
679897002112	putative active site [active]
679897002113	substrate binding site [chemical binding]; other site
679897002114	putative cosubstrate binding site; other site
679897002115	catalytic site [active]
679897002116	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
679897002117	substrate binding site [chemical binding]; other site
679897002118	HMMPfam hit to PF00551, Formyl_trans_N, score 5.7e-29
679897002119	HMMPfam hit to PF02911, Formyl_trans_C, score 8.1e-13
679897002120	biotin--protein ligase; Provisional; Region: PRK08477
679897002121	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
679897002122	HMMPfam hit to PF03099, BPL_LipA_LipB, score 1.9e-07
679897002123	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
679897002124	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
679897002125	P-loop; other site
679897002126	Magnesium ion binding site [ion binding]; other site
679897002127	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
679897002128	Magnesium ion binding site [ion binding]; other site
679897002129	HMMPfam hit to PF01656, CbiA, score 3.3e-54
679897002130	PS00435 Peroxidases proximal heme-ligand signature.
679897002131	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
679897002132	ParB-like nuclease domain; Region: ParBc; pfam02195
679897002133	HMMPfam hit to PF02195, ParBc, score 1.3e-32
679897002134	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
679897002135	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
679897002136	1 probable transmembrane helix predicted for HMU04300 by TMHMM2.0 at aa 4-26
679897002137	F0F1 ATP synthase subunit B; Validated; Region: PRK08475
679897002138	ATP synthase B/B' CF(0); Region: ATP-synt_B; pfam00430
679897002139	Signal peptide predicted for HMU04310 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.991 between residues 27 and 28
679897002140	HMMPfam hit to PF00430, ATP-synt_B, score 1.5e-05
679897002141	1 probable transmembrane helix predicted for HMU04310 by TMHMM2.0 at aa 31-50
679897002142	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
679897002143	HMMPfam hit to PF00213, OSCP, score 5.5e-07
679897002144	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
679897002145	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
679897002146	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
679897002147	beta subunit interaction interface [polypeptide binding]; other site
679897002148	Walker A motif; other site
679897002149	ATP binding site [chemical binding]; other site
679897002150	Walker B motif; other site
679897002151	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
679897002152	HMMPfam hit to PF02874, ATP-synt_ab_N, score 3.9e-14
679897002153	HMMPfam hit to PF00006, ATP-synt_ab, score 1.3e-122
679897002154	PS00017 ATP/GTP-binding site motif A (P-loop).
679897002155	PS00152 ATP synthase alpha and beta subunits signature.
679897002156	HMMPfam hit to PF00306, ATP-synt_ab_C, score 2.6e-38
679897002157	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
679897002158	core domain interface [polypeptide binding]; other site
679897002159	delta subunit interface [polypeptide binding]; other site
679897002160	epsilon subunit interface [polypeptide binding]; other site
679897002161	HMMPfam hit to PF00231, ATP-synt, score 2.5e-83
679897002162	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
679897002163	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
679897002164	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
679897002165	alpha subunit interaction interface [polypeptide binding]; other site
679897002166	Walker A motif; other site
679897002167	ATP binding site [chemical binding]; other site
679897002168	Walker B motif; other site
679897002169	inhibitor binding site; inhibition site
679897002170	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
679897002171	HMMPfam hit to PF02874, ATP-synt_ab_N, score 3.6e-22
679897002172	HMMPfam hit to PF00006, ATP-synt_ab, score 7.7e-99
679897002173	PS00017 ATP/GTP-binding site motif A (P-loop).
679897002174	PS00152 ATP synthase alpha and beta subunits signature.
679897002175	HMMPfam hit to PF00306, ATP-synt_ab_C, score 1.5e-54
679897002176	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
679897002177	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
679897002178	gamma subunit interface [polypeptide binding]; other site
679897002179	epsilon subunit interface [polypeptide binding]; other site
679897002180	LBP interface [polypeptide binding]; other site
679897002181	HMMPfam hit to PF02823, ATP-synt_DE_N, score 1.1e-17
679897002182	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
679897002183	3 probable transmembrane helices predicted for HMU04370 by TMHMM2.0 at aa 13-35, 91-113 and 140-161
679897002184	HMMPfam hit to PF01618, MotA_ExbB, score 7.3e-31
679897002185	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
679897002186	TolR protein; Region: tolR; TIGR02801
679897002187	HMMPfam hit to PF02472, ExbD, score 9.6e-08
679897002188	1 probable transmembrane helix predicted for HMU04380 by TMHMM2.0 at aa 15-34
679897002189	TonB C terminal; Region: TonB_2; pfam13103
679897002190	Signal peptide predicted for HMU04390 by SignalP 2.0 HMM (Signal peptide probability 0.959) with cleavage site probability 0.767 between residues 33 and 34
679897002191	1 probable transmembrane helix predicted for HMU04390 by TMHMM2.0 at aa 7-29
679897002192	translocation protein TolB; Provisional; Region: tolB; PRK04043
679897002193	TolB amino-terminal domain; Region: TolB_N; pfam04052
679897002194	HMMPfam hit to PF04052, TolB_N, score 2.2e-15
679897002195	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
679897002196	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
679897002197	ligand binding site [chemical binding]; other site
679897002198	Signal peptide predicted for HMU04410 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.688 between residues 23 and 24
679897002199	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002200	HMMPfam hit to PF00691, OmpA, score 1.7e-27
679897002201	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
679897002202	Signal peptide predicted for HMU04420 by SignalP 2.0 HMM (Signal peptide probability 0.779) with cleavage site probability 0.304 between residues 26 and 27
679897002203	HMMPfam hit to PF07719, TPR_2, score 0.00011
679897002204	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
679897002205	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
679897002206	HMMPfam hit to PF00254, FKBP_C, score 2.4e-10
679897002207	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002208	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
679897002209	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
679897002210	catalytic residues [active]
679897002211	HMMPfam hit to PF00977, His_biosynth, score 1.1e-93
679897002212	Methyltransferase domain; Region: Methyltransf_26; pfam13659
679897002213	HMMPfam hit to PF02384, N6_Mtase, score 1.5e-09
679897002214	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
679897002215	putative trimer interface [polypeptide binding]; other site
679897002216	putative active site [active]
679897002217	putative substrate binding site [chemical binding]; other site
679897002218	putative CoA binding site [chemical binding]; other site
679897002219	HMMPfam hit to PF00132, Hexapep, score 14
679897002220	HMMPfam hit to PF00132, Hexapep, score 6
679897002221	HMMPfam hit to PF00132, Hexapep, score 11
679897002222	HMMPfam hit to PF00132, Hexapep, score 0.14
679897002223	Signal peptide predicted for HMU04470 by SignalP 2.0 HMM (Signal peptide probability 0.624) with cleavage site probability 0.466 between residues 26 and 27
679897002224	1 probable transmembrane helix predicted for HMU04470 by TMHMM2.0 at aa 9-31
679897002225	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
679897002226	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08471
679897002227	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
679897002228	Protein of unknown function (DUF2400); Region: DUF2400; pfam09674
679897002229	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
679897002230	HMMPfam hit to PF00830, Ribosomal_L28, score 4.5e-17
679897002231	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
679897002232	3 probable transmembrane helices predicted for HMU04530 by TMHMM2.0 at aa 15-34, 55-77 and 119-141
679897002233	HMMPfam hit to PF01066, CDP-OH_P_transf, score 3.6e-31
679897002234	PS00379 CDP-alcohol phosphatidyltransferases signature.
679897002235	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
679897002236	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
679897002237	active site
679897002238	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
679897002239	protein binding site [polypeptide binding]; other site
679897002240	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
679897002241	putative substrate binding region [chemical binding]; other site
679897002242	4 probable transmembrane helices predicted for HMU04540 by TMHMM2.0 at aa 2-24, 93-115, 271-293 and 321-340
679897002243	HMMPfam hit to PF02163, Peptidase_M50, score 1.4e-68
679897002244	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
679897002245	HMMPfam hit to PF00595, PDZ, score 4.2e-05
679897002246	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
679897002247	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
679897002248	generic binding surface II; other site
679897002249	generic binding surface I; other site
679897002250	HMMPfam hit to PF01336, tRNA_anti, score 9.8e-14
679897002251	HMMPfam hit to PF02601, Exonuc_VII_L, score 7.7e-41
679897002252	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
679897002253	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
679897002254	PS00041 Bacterial regulatory proteins, araC family signature.
679897002255	HMMPfam hit to PF00023, Ank, score 1.4e-10
679897002256	HMMPfam hit to PF00023, Ank, score 8.7e-07
679897002257	HMMPfam hit to PF00023, Ank, score 4.4e-05
679897002258	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
679897002259	nucleotide binding site/active site [active]
679897002260	HIT family signature motif; other site
679897002261	catalytic residue [active]
679897002262	HMMPfam hit to PF01230, HIT, score 1.4e-06
679897002263	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
679897002264	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
679897002265	HMMPfam hit to PF08245, Mur_ligase_M, score 1.8e-18
679897002266	5 probable transmembrane helices predicted for HMU04580 by TMHMM2.0 at aa 4-23, 44-63, 67-89, 102-121 and 126-148
679897002267	Acylphosphatase; Region: Acylphosphatase; pfam00708
679897002268	HMMPfam hit to PF00708, Acylphosphatase, score 1.6e-05
679897002269	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
679897002270	HMMPfam hit to PF00561, Abhydrolase_1, score 8.9e-05
679897002271	HMMPfam hit to PF00561, Abhydrolase_1, score 2.3e-06
679897002272	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
679897002273	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
679897002274	ATP-grasp domain; Region: ATP-grasp_4; cl17255
679897002275	HMMPfam hit to PF07478, Dala_Dala_lig_C, score 2.3e-19
679897002276	HMMPfam hit to PF01820, Dala_Dala_lig_N, score 8.3e-11
679897002277	PS00843 D-alanine--D-alanine ligase signature 1.
679897002278	type II citrate synthase; Reviewed; Region: gltA; PRK05614
679897002279	Citrate synthase; Region: Citrate_synt; pfam00285
679897002280	oxalacetate binding site [chemical binding]; other site
679897002281	citrylCoA binding site [chemical binding]; other site
679897002282	coenzyme A binding site [chemical binding]; other site
679897002283	catalytic triad [active]
679897002284	HMMPfam hit to PF00285, Citrate_synt, score 3.5e-143
679897002285	PS00480 Citrate synthase signature.
679897002286	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
679897002287	HMMPfam hit to PF03435, Saccharop_dh, score 3.1e-179
679897002288	PS00017 ATP/GTP-binding site motif A (P-loop).
679897002289	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
679897002290	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
679897002291	active site
679897002292	homodimer interface [polypeptide binding]; other site
679897002293	HMMPfam hit to PF03033, Glyco_transf_28, score 3.1e-19
679897002294	HMMPfam hit to PF04101, Glyco_tran_28_C, score 5.1e-38
679897002295	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
679897002296	elongation factor Ts; Provisional; Region: tsf; PRK09377
679897002297	UBA/TS-N domain; Region: UBA; pfam00627
679897002298	Elongation factor TS; Region: EF_TS; pfam00889
679897002299	Elongation factor TS; Region: EF_TS; pfam00889
679897002300	HMMPfam hit to PF00889, EF_TS, score 1.9e-43
679897002301	PS01127 Elongation factor Ts signature 2.
679897002302	HMMPfam hit to PF00627, UBA, score 2.7e-15
679897002303	PS01126 Elongation factor Ts signature 1.
679897002304	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
679897002305	rRNA interaction site [nucleotide binding]; other site
679897002306	S8 interaction site; other site
679897002307	putative laminin-1 binding site; other site
679897002308	HMMPfam hit to PF00318, Ribosomal_S2, score 2.6e-98
679897002309	PS00963 Ribosomal protein S2 signature 2.
679897002310	PS00962 Ribosomal protein S2 signature 1.
679897002311	2-oxoglutarate-acceptor oxidoreductase subunit OorC; Reviewed; Region: oorC; PRK08441
679897002312	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
679897002313	HMMPfam hit to PF01558, POR, score 2.1e-32
679897002314	2-oxoglutarate-acceptor oxidoreductase subunit OorB; Reviewed; Region: oorB; PRK09628
679897002315	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
679897002316	TPP-binding site [chemical binding]; other site
679897002317	HMMPfam hit to PF02775, TPP_enzyme_C, score 1.4e-52
679897002318	2-oxoglutarate-acceptor oxidoreductase subunit OorA; Reviewed; Region: oorA; PRK09627
679897002319	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
679897002320	dimer interface [polypeptide binding]; other site
679897002321	PYR/PP interface [polypeptide binding]; other site
679897002322	TPP binding site [chemical binding]; other site
679897002323	substrate binding site [chemical binding]; other site
679897002324	HMMPfam hit to PF01855, POR_N, score 2.4e-95
679897002325	PS00228 Tubulin-beta mRNA autoregulation signal.
679897002326	2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed; Region: oorD; PRK09626
679897002327	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
679897002328	HMMPfam hit to PF00037, Fer4, score 3.3e-05
679897002329	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897002330	HMMPfam hit to PF00037, Fer4, score 1.1e-05
679897002331	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897002332	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
679897002333	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
679897002334	dimerization interface [polypeptide binding]; other site
679897002335	HMMPfam hit to PF02618, ADC_lyase, score 3.6e-60
679897002336	1 probable transmembrane helix predicted for HMU04760 by TMHMM2.0 at aa 9-31
679897002337	Protein of unknown function; Region: DUF3971; pfam13116
679897002338	AsmA-like C-terminal region; Region: AsmA_1; pfam13109
679897002339	FeoA domain; Region: FeoA; pfam04023
679897002340	HMMPfam hit to PF04023, FeoA, score 1.5e-10
679897002341	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
679897002342	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
679897002343	minor groove reading motif; other site
679897002344	helix-hairpin-helix signature motif; other site
679897002345	substrate binding pocket [chemical binding]; other site
679897002346	active site
679897002347	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
679897002348	HMMPfam hit to PF00730, HhH-GPD, score 2.3e-21
679897002349	HMMPfam hit to PF00633, HHH, score 6.7e-06
679897002350	PS00764 Endonuclease III iron-sulfur binding region signature.
679897002351	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
679897002352	flagellar motor switch protein; Validated; Region: PRK08433
679897002353	HMMPfam hit to PF01052, SpoA, score 1.4e-27
679897002354	Signal peptide predicted for HMU04820 by SignalP 2.0 HMM (Signal peptide probability 0.981) with cleavage site probability 0.822 between residues 25 and 26
679897002355	1 probable transmembrane helix predicted for HMU04820 by TMHMM2.0 at aa 167-189
679897002356	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
679897002357	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
679897002358	Signal peptide predicted for HMU04830 by SignalP 2.0 HMM (Signal peptide probability 0.744) with cleavage site probability 0.551 between residues 33 and 34
679897002359	1 probable transmembrane helix predicted for HMU04830 by TMHMM2.0 at aa 9-31
679897002360	Arginase family; Region: Arginase; cd09989
679897002361	active site
679897002362	Mn binding site [ion binding]; other site
679897002363	oligomer interface [polypeptide binding]; other site
679897002364	HMMPfam hit to PF00491, Arginase, score 8.4e-10
679897002365	PS00148 Arginase family signature 2.
679897002366	S-methylmethionine transporter; Provisional; Region: PRK11387
679897002367	HMMPfam hit to PF00324, AA_permease, score 3.8e-119
679897002368	12 probable transmembrane helices predicted for HMU04850 by TMHMM2.0 at aa 21-40, 44-66, 94-116, 126-148, 161-183, 208-230, 249-271, 299-321, 342-364, 377-399, 419-441 and 446-465
679897002369	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002370	PS00218 Amino acid permeases signature.
679897002371	Signal peptide predicted for HMU04850 by SignalP 2.0 HMM (Signal peptide probability 0.962) with cleavage site probability 0.870 between residues 42 and 43
679897002372	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
679897002373	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
679897002374	hexamer interface [polypeptide binding]; other site
679897002375	ligand binding site [chemical binding]; other site
679897002376	putative active site [active]
679897002377	NAD(P) binding site [chemical binding]; other site
679897002378	potential protein location ( alanine dehydrogenase 1 [Helicobacter mustelae 12198]) that overlaps RNA (23S ribosomal RNA)
679897002379	HMMPfam hit to PF05222, AlaDh_PNT_N, score 1.9e-58
679897002380	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
679897002381	potential protein location ( ligase/carboxylase [Helicobacter mustelae 12198]) that overlaps RNA (23S ribosomal RNA)
679897002382	PS00030 Eukaryotic  RNA-binding region RNP-1 signature.
679897002383	HMMPfam hit to PF02222, ATP-grasp, score 5.5e-09
679897002384	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
679897002385	1 probable transmembrane helix predicted for HMU04900 by TMHMM2.0 at aa 13-32
679897002386	HMMPfam hit to PF01266, DAO, score 7.3e-50
679897002387	PS00017 ATP/GTP-binding site motif A (P-loop).
679897002388	PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2.
679897002389	glycerol kinase; Provisional; Region: glpK; PRK00047
679897002390	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
679897002391	N- and C-terminal domain interface [polypeptide binding]; other site
679897002392	active site
679897002393	MgATP binding site [chemical binding]; other site
679897002394	catalytic site [active]
679897002395	metal binding site [ion binding]; metal-binding site
679897002396	glycerol binding site [chemical binding]; other site
679897002397	homotetramer interface [polypeptide binding]; other site
679897002398	homodimer interface [polypeptide binding]; other site
679897002399	FBP binding site [chemical binding]; other site
679897002400	protein IIAGlc interface [polypeptide binding]; other site
679897002401	HMMPfam hit to PF00370, FGGY_N, score 1.5e-114
679897002402	PS00933 FGGY family of carbohydrate kinases signature 1.
679897002403	HMMPfam hit to PF02782, FGGY_C, score 4.3e-82
679897002404	PS00445 FGGY family of carbohydrate kinases signature 2.
679897002405	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
679897002406	amphipathic channel; other site
679897002407	Asn-Pro-Ala signature motifs; other site
679897002408	HMMPfam hit to PF00230, MIP, score 2.5e-19
679897002409	6 probable transmembrane helices predicted for HMU04920 by TMHMM2.0 at aa 2-24, 39-61, 82-104, 139-161, 168-190 and 219-241
679897002410	PS00221 MIP family signature.
679897002411	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
679897002412	HMMPfam hit to PF01856, HP_OMP, score 7.2e-18
679897002413	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
679897002414	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
679897002415	active site
679897002416	intersubunit interface [polypeptide binding]; other site
679897002417	catalytic residue [active]
679897002418	HMMPfam hit to PF01081, Aldolase, score 6.4e-99
679897002419	PS00402 Binding-protein-dependent transport systems inner membrane comp. sign.
679897002420	PS00160 KDPG and KHG aldolases Schiff-base forming residue.
679897002421	PS00159 KDPG and KHG aldolases active site.
679897002422	phosphogluconate dehydratase; Validated; Region: PRK09054
679897002423	6-phosphogluconate dehydratase; Region: edd; TIGR01196
679897002424	HMMPfam hit to PF00920, ILVD_EDD, score 2e-261
679897002425	PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2.
679897002426	PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1.
679897002427	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
679897002428	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
679897002429	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
679897002430	HMMPfam hit to PF00479, G6PD_N, score 2.8e-79
679897002431	PS00069 Glucose-6-phosphate dehydrogenase active site.
679897002432	HMMPfam hit to PF02781, G6PD_C, score 7.2e-99
679897002433	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
679897002434	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
679897002435	putative active site [active]
679897002436	glucokinase; Provisional; Region: glk; PRK00292
679897002437	glucokinase, proteobacterial type; Region: glk; TIGR00749
679897002438	HMMPfam hit to PF02685, Glucokinase, score 8e-163
679897002439	1 probable transmembrane helix predicted for HMU04980 by TMHMM2.0 at aa 298-320
679897002440	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
679897002441	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
679897002442	active site
679897002443	dimer interface [polypeptide binding]; other site
679897002444	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
679897002445	dimer interface [polypeptide binding]; other site
679897002446	active site
679897002447	HMMPfam hit to PF00342, PGI, score 6.6e-262
679897002448	PS00765 Phosphoglucose isomerase signature 1.
679897002449	PS00174 Phosphoglucose isomerase signature 2.
679897002450	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
679897002451	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
679897002452	putative substrate translocation pore; other site
679897002453	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
679897002454	Signal peptide predicted for HMU05000 by SignalP 2.0 HMM (Signal peptide probability 0.922) with cleavage site probability 0.645 between residues 27 and 28
679897002455	12 probable transmembrane helices predicted for HMU05000 by TMHMM2.0 at aa 7-26, 41-63, 70-92, 102-124, 137-159, 174-196, 225-247, 265-287, 292-309, 313-335, 347-369 and 374-393
679897002456	HMMPfam hit to PF07690, MFS_1, score 4.8e-30
679897002457	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002458	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002459	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
679897002460	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
679897002461	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
679897002462	HMMPfam hit to PF05378, Hydant_A_N, score 3.7e-13
679897002463	HMMPfam hit to PF01968, Hydantoinase_A, score 5.2e-74
679897002464	Acetone carboxylase, gamma subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcxC; COG4647
679897002465	HMMPfam hit to PF08882, Acetone_carb_G, score 1.4e-43
679897002466	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
679897002467	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
679897002468	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
679897002469	HMMPfam hit to PF05378, Hydant_A_N, score 1.7e-45
679897002470	HMMPfam hit to PF01968, Hydantoinase_A, score 2.1e-74
679897002471	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
679897002472	Hydantoinase B/oxoprolinase; Region: Hydantoinase_B; pfam02538
679897002473	HMMPfam hit to PF02538, Hydantoinase_B, score 3.6e-13
679897002474	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002475	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Region: HAD-SF-IA-v1; TIGR01549
679897002476	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
679897002477	active site
679897002478	motif I; other site
679897002479	motif II; other site
679897002480	HMMPfam hit to PF03767, Acid_phosphat_B, score 6.7e-61
679897002481	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
679897002482	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
679897002483	HMMPfam hit to PF01702, TGT, score 7.2e-119
679897002484	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002485	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3400
679897002486	TrkA-C domain; Region: TrkA_C; pfam02080
679897002487	HMMPfam hit to PF02080, TrkA_C, score 1.4e-06
679897002488	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
679897002489	active site
679897002490	dimer interface [polypeptide binding]; other site
679897002491	metal binding site [ion binding]; metal-binding site
679897002492	HMMPfam hit to PF01761, DHQ_synthase, score 1.2e-140
679897002493	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
679897002494	Mechanosensitive ion channel; Region: MS_channel; pfam00924
679897002495	3 probable transmembrane helices predicted for HMU05100 by TMHMM2.0 at aa 224-246, 266-288 and 308-327
679897002496	HMMPfam hit to PF00924, MS_channel, score 6.3e-27
679897002497	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
679897002498	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
679897002499	HMMPfam hit to PF00919, UPF0004, score 2e-26
679897002500	HMMPfam hit to PF04055, Radical_SAM, score 2.4e-22
679897002501	PS01278 Uncharacterized protein family UPF0004 signature.
679897002502	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
679897002503	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897002504	ATP binding site [chemical binding]; other site
679897002505	Walker B motif; other site
679897002506	arginine finger; other site
679897002507	1 probable transmembrane helix predicted for HMU05120 by TMHMM2.0 at aa 77-94
679897002508	HMMPfam hit to PF00004, AAA, score 5.3e-81
679897002509	PS00017 ATP/GTP-binding site motif A (P-loop).
679897002510	PS00674 AAA-protein family signature.
679897002511	3 probable transmembrane helices predicted for HMU05140 by TMHMM2.0 at aa 10-32, 37-59 and 87-109
679897002512	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
679897002513	Methyltransferase domain; Region: Methyltransf_26; pfam13659
679897002514	HMMPfam hit to PF02384, N6_Mtase, score 1.2e-12
679897002515	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
679897002516	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
679897002517	heat shock protein 90; Provisional; Region: PRK05218
679897002518	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
679897002519	ATP binding site [chemical binding]; other site
679897002520	Mg2+ binding site [ion binding]; other site
679897002521	G-X-G motif; other site
679897002522	HMMPfam hit to PF00183, HSP90, score 3.6e-78
679897002523	HMMPfam hit to PF02518, HATPase_c, score 1.1e-12
679897002524	PS00298 Heat shock hsp90 proteins family signature.
679897002525	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002526	DJ-1 family protein; Region: not_thiJ; TIGR01383
679897002527	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
679897002528	conserved cys residue [active]
679897002529	HMMPfam hit to PF01965, DJ-1_PfpI, score 1.9e-27
679897002530	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
679897002531	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
679897002532	GTP-binding protein LepA; Provisional; Region: PRK05433
679897002533	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
679897002534	G1 box; other site
679897002535	putative GEF interaction site [polypeptide binding]; other site
679897002536	GTP/Mg2+ binding site [chemical binding]; other site
679897002537	Switch I region; other site
679897002538	G2 box; other site
679897002539	G3 box; other site
679897002540	Switch II region; other site
679897002541	G4 box; other site
679897002542	G5 box; other site
679897002543	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
679897002544	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
679897002545	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
679897002546	HMMPfam hit to PF00009, GTP_EFTU, score 8.7e-74
679897002547	PS00017 ATP/GTP-binding site motif A (P-loop).
679897002548	PS00301 GTP-binding elongation factors signature.
679897002549	HMMPfam hit to PF03144, GTP_EFTU_D2, score 2.5e-10
679897002550	HMMPfam hit to PF00679, EFG_C, score 8.9e-36
679897002551	HMMPfam hit to PF06421, LepA_C, score 3.1e-78
679897002552	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
679897002553	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
679897002554	dimerization interface [polypeptide binding]; other site
679897002555	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
679897002556	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
679897002557	dimer interface [polypeptide binding]; other site
679897002558	putative CheW interface [polypeptide binding]; other site
679897002559	Signal peptide predicted for HMU05230 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.480 between residues 26 and 27
679897002560	2 probable transmembrane helices predicted for HMU05230 by TMHMM2.0 at aa 7-29 and 210-232
679897002561	HMMPfam hit to PF00672, HAMP, score 6.4e-13
679897002562	HMMPfam hit to PF00015, MCPsignal, score 8.2e-36
679897002563	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
679897002564	HMMPfam hit to PF02272, DHHA1, score 0.00034
679897002565	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
679897002566	FHIPEP family; Region: FHIPEP; pfam00771
679897002567	HMMPfam hit to PF00771, FHIPEP, score 0
679897002568	7 probable transmembrane helices predicted for HMU05260 by TMHMM2.0 at aa 25-47, 51-69, 74-96, 122-144, 213-232, 242-264 and 297-331
679897002569	Signal peptide predicted for HMU05260 by SignalP 2.0 HMM (Signal peptide probability 0.920) with cleavage site probability 0.448 between residues 56 and 57
679897002570	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
679897002571	16S/18S rRNA binding site [nucleotide binding]; other site
679897002572	S13e-L30e interaction site [polypeptide binding]; other site
679897002573	25S rRNA binding site [nucleotide binding]; other site
679897002574	HMMPfam hit to PF00312, Ribosomal_S15, score 1.2e-32
679897002575	PS00362 Ribosomal protein S15 signature.
679897002576	Putative lipopolysaccharide-modifying enzyme; Region: CAP10; smart00672
679897002577	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
679897002578	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
679897002579	active site
679897002580	HMMPfam hit to PF00535, Glycos_transf_2, score 4e-40
679897002581	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
679897002582	dimer interface [polypeptide binding]; other site
679897002583	putative radical transfer pathway; other site
679897002584	diiron center [ion binding]; other site
679897002585	tyrosyl radical; other site
679897002586	HMMPfam hit to PF00268, Ribonuc_red_sm, score 7.3e-21
679897002587	PS00368 Ribonucleotide reductase small subunit signature.
679897002588	1 probable transmembrane helix predicted for HMU05330 by TMHMM2.0 at aa 190-212
679897002589	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
679897002590	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897002591	S-adenosylmethionine binding site [chemical binding]; other site
679897002592	HMMPfam hit to PF01135, PCMT, score 2.4e-59
679897002593	6 probable transmembrane helices predicted for HMU05350 by TMHMM2.0 at aa 20-42, 49-71, 86-108, 113-135, 145-167 and 180-202
679897002594	HMMPfam hit to PF01478, Peptidase_A24, score 2.1e-11
679897002595	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
679897002596	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
679897002597	Signal peptide predicted for HMU05360 by SignalP 2.0 HMM (Signal peptide probability 0.691) with cleavage site probability 0.418 between residues 34 and 35
679897002598	HMMPfam hit to PF03739, YjgP_YjgQ, score 2.1e-41
679897002599	6 probable transmembrane helices predicted for HMU05360 by TMHMM2.0 at aa 13-35, 50-72, 98-120, 258-280, 287-306 and 311-330
679897002600	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002601	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
679897002602	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
679897002603	dimerization interface 3.5A [polypeptide binding]; other site
679897002604	active site
679897002605	HMMPfam hit to PF01416, PseudoU_synth_1, score 1.2e-24
679897002606	HMMPfam hit to PF01416, PseudoU_synth_1, score 3.4e-08
679897002607	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
679897002608	23S rRNA interface [nucleotide binding]; other site
679897002609	L3 interface [polypeptide binding]; other site
679897002610	HMMPfam hit to PF00572, Ribosomal_L13, score 5e-50
679897002611	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
679897002612	HMMPfam hit to PF00380, Ribosomal_S9, score 8.3e-45
679897002613	PS00360 Ribosomal protein S9 signature.
679897002614	pyruvate flavodoxin oxidoreductase subunit gamma; Validated; Region: PRK05844
679897002615	pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; Provisional; Region: PRK14029
679897002616	HMMPfam hit to PF01558, POR, score 4.2e-48
679897002617	pyruvate flavodoxin oxidoreductase subunit delta; Reviewed; Region: porD; PRK09625
679897002618	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
679897002619	HMMPfam hit to PF00037, Fer4, score 0.0016
679897002620	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897002621	HMMPfam hit to PF00037, Fer4, score 1.4e-05
679897002622	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897002623	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
679897002624	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
679897002625	dimer interface [polypeptide binding]; other site
679897002626	PYR/PP interface [polypeptide binding]; other site
679897002627	TPP binding site [chemical binding]; other site
679897002628	substrate binding site [chemical binding]; other site
679897002629	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
679897002630	HMMPfam hit to PF01855, POR_N, score 2.2e-101
679897002631	PS00099 Thiolases active site.
679897002632	HMMPfam hit to PF02780, Transketolase_C, score 0.0058
679897002633	Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea...; Region: TPP_PFOR_porB_like; cd03376
679897002634	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
679897002635	TPP-binding site [chemical binding]; other site
679897002636	putative dimer interface [polypeptide binding]; other site
679897002637	HMMPfam hit to PF02775, TPP_enzyme_C, score 2.5e-30
679897002638	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002639	aminodeoxychorismate synthase; Provisional; Region: PRK07508
679897002640	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
679897002641	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
679897002642	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
679897002643	substrate-cofactor binding pocket; other site
679897002644	homodimer interface [polypeptide binding]; other site
679897002645	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897002646	catalytic residue [active]
679897002647	HMMPfam hit to PF00425, Chorismate_bind, score 9.1e-49
679897002648	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
679897002649	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
679897002650	Glutamine amidotransferase class-I; Region: GATase; pfam00117
679897002651	glutamine binding [chemical binding]; other site
679897002652	catalytic triad [active]
679897002653	HMMPfam hit to PF00117, GATase, score 1.7e-53
679897002654	acyl carrier protein; Provisional; Region: acpP; PRK00982
679897002655	HMMPfam hit to PF00550, PP-binding, score 1e-21
679897002656	PS00012 Phosphopantetheine attachment site.
679897002657	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK08439
679897002658	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
679897002659	dimer interface [polypeptide binding]; other site
679897002660	active site
679897002661	HMMPfam hit to PF00109, ketoacyl-synt, score 7.9e-69
679897002662	HMMPfam hit to PF02801, Ketoacyl-synt_C, score 4.9e-49
679897002663	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
679897002664	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; pfam03255
679897002665	HMMPfam hit to PF03255, ACCA, score 1.4e-62
679897002666	HMMPfam hit to PF01039, Carboxyl_trans, score 5.3e-05
679897002667	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
679897002668	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
679897002669	Ligand Binding Site [chemical binding]; other site
679897002670	HMMPfam hit to PF03054, tRNA_Me_trans, score 1.1e-136
679897002671	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
679897002672	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
679897002673	N-terminal plug; other site
679897002674	ligand-binding site [chemical binding]; other site
679897002675	HMMPfam hit to PF00593, TonB_dep_Rec, score 3.6e-22
679897002676	PS00221 MIP family signature.
679897002677	HMMPfam hit to PF07715, Plug, score 6.5e-20
679897002678	hypothetical protein; Provisional; Region: PRK11018
679897002679	CPxP  motif; other site
679897002680	HMMPfam hit to PF01206, SirA, score 1.7e-24
679897002681	putative inner membrane protein; Provisional; Region: PRK11099
679897002682	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
679897002683	10 probable transmembrane helices predicted for HMU05530 by TMHMM2.0 at aa 13-35, 80-102, 115-137, 147-169, 192-214, 220-242, 255-277, 292-314, 321-343 and 363-385
679897002684	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002685	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002686	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
679897002687	HMMPfam hit to PF00753, Lactamase_B, score 2e-29
679897002688	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
679897002689	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
679897002690	substrate binding site [chemical binding]; other site
679897002691	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
679897002692	substrate binding site [chemical binding]; other site
679897002693	ligand binding site [chemical binding]; other site
679897002694	HMMPfam hit to PF00330, Aconitase, score 2.8e-12
679897002695	PS00450 Aconitase family signature 1.
679897002696	HMMPfam hit to PF06434, Aconitase_2_N, score 1.5e-228
679897002697	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
679897002698	Putative catalytic NodB homology domain of uncharacterized BH0857 protein from Bacillus halodurans and its bacterial homologs; Region: CE4_BH0857_like; cd10955
679897002699	NodB motif; other site
679897002700	putative active site [active]
679897002701	putative catalytic site [active]
679897002702	HMMPfam hit to PF01522, Polysacc_deac_1, score 1.2e-16
679897002703	Signal peptide predicted for HMU05560 by SignalP 2.0 HMM (Signal peptide probability 0.898) with cleavage site probability 0.424 between residues 30 and 31
679897002704	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
679897002705	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
679897002706	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
679897002707	putative active site [active]
679897002708	putative substrate binding site [chemical binding]; other site
679897002709	putative cosubstrate binding site; other site
679897002710	catalytic site [active]
679897002711	HMMPfam hit to PF00551, Formyl_trans_N, score 8.2e-49
679897002712	HMMPfam hit to PF01842, ACT, score 1.1e-06
679897002713	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
679897002714	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
679897002715	tandem repeat interface [polypeptide binding]; other site
679897002716	oligomer interface [polypeptide binding]; other site
679897002717	active site residues [active]
679897002718	HMMPfam hit to PF01343, Peptidase_S49, score 1.9e-53
679897002719	Signal peptide predicted for HMU05580 by SignalP 2.0 HMM (Signal peptide probability 0.913) with cleavage site probability 0.621 between residues 41 and 42
679897002720	1 probable transmembrane helix predicted for HMU05580 by TMHMM2.0 at aa 7-29
679897002721	methionine sulfoxide reductase B; Provisional; Region: PRK05508
679897002722	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
679897002723	HMMPfam hit to PF01641, SelR, score 1.2e-56
679897002724	Uncharacterized conserved protein [Function unknown]; Region: COG0062
679897002725	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
679897002726	putative substrate binding site [chemical binding]; other site
679897002727	putative ATP binding site [chemical binding]; other site
679897002728	HMMPfam hit to PF03853, YjeF_N, score 5.6e-37
679897002729	HMMPfam hit to PF01256, Carb_kinase, score 3.7e-37
679897002730	PS01050 Uncharacterized protein family UPF0031 signature 2.
679897002731	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
679897002732	dinuclear metal binding motif [ion binding]; other site
679897002733	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
679897002734	active site
679897002735	HMMPfam hit to PF00160, Pro_isomerase, score 1e-42
679897002736	PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature.
679897002737	Signal peptide predicted for HMU05630 by SignalP 2.0 HMM (Signal peptide probability 0.962) with cleavage site probability 0.668 between residues 23 and 24
679897002738	PS00387 Inorganic pyrophosphatase signature.
679897002739	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
679897002740	HMMPfam hit to PF02521, HP_OMP_2, score 2.4e-85
679897002741	Signal peptide predicted for HMU05640 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.268 between residues 20 and 21
679897002742	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
679897002743	HMMPfam hit to PF02521, HP_OMP_2, score 1.9e-112
679897002744	Signal peptide predicted for HMU05650 by SignalP 2.0 HMM (Signal peptide probability 0.788) with cleavage site probability 0.271 between residues 27 and 28
679897002745	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
679897002746	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
679897002747	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
679897002748	HMMPfam hit to PF00185, OTCace, score 1.5e-13
679897002749	HMMPfam hit to PF02729, OTCace_N, score 2.8e-35
679897002750	PS00097 Aspartate and ornithine carbamoyltransferases signature.
679897002751	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
679897002752	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
679897002753	RNA binding surface [nucleotide binding]; other site
679897002754	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897002755	S-adenosylmethionine binding site [chemical binding]; other site
679897002756	HMMPfam hit to PF01479, S4, score 4.8e-09
679897002757	HMMPfam hit to PF01728, FtsJ, score 8.9e-06
679897002758	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
679897002759	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
679897002760	active site
679897002761	nucleotide binding site [chemical binding]; other site
679897002762	HIGH motif; other site
679897002763	KMSKS motif; other site
679897002764	Riboflavin kinase; Region: Flavokinase; smart00904
679897002765	HMMPfam hit to PF06574, FAD_syn, score 4.1e-11
679897002766	HMMPfam hit to PF01687, Flavokinase, score 4.1e-24
679897002767	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
679897002768	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
679897002769	TPP-binding site [chemical binding]; other site
679897002770	dimer interface [polypeptide binding]; other site
679897002771	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
679897002772	PYR/PP interface [polypeptide binding]; other site
679897002773	dimer interface [polypeptide binding]; other site
679897002774	TPP binding site [chemical binding]; other site
679897002775	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
679897002776	HMMPfam hit to PF00456, Transketolase_N, score 4.1e-141
679897002777	HMMPfam hit to PF02779, Transket_pyr, score 5e-59
679897002778	PS00802 Transketolase signature 2.
679897002779	HMMPfam hit to PF02780, Transketolase_C, score 0.00061
679897002780	Inactivated superfamily I helicase [DNA replication, recombination, and repair]; Region: COG3893
679897002781	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
679897002782	PS00017 ATP/GTP-binding site motif A (P-loop).
679897002783	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
679897002784	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
679897002785	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
679897002786	Signal peptide predicted for HMU05740 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.377 between residues 41 and 42
679897002787	5 probable transmembrane helices predicted for HMU05740 by TMHMM2.0 at aa 17-39, 54-76, 89-108, 123-140 and 142-164
679897002788	HMMPfam hit to PF01580, FtsK_SpoIIIE, score 4.5e-81
679897002789	PS00017 ATP/GTP-binding site motif A (P-loop).
679897002790	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
679897002791	substrate binding site [chemical binding]; other site
679897002792	active site
679897002793	catalytic residues [active]
679897002794	heterodimer interface [polypeptide binding]; other site
679897002795	HMMPfam hit to PF00290, Trp_syntA, score 3e-51
679897002796	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
679897002797	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
679897002798	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897002799	catalytic residue [active]
679897002800	HMMPfam hit to PF00291, PALP, score 9.7e-96
679897002801	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002802	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
679897002803	active site
679897002804	ribulose/triose binding site [chemical binding]; other site
679897002805	phosphate binding site [ion binding]; other site
679897002806	substrate (anthranilate) binding pocket [chemical binding]; other site
679897002807	product (indole) binding pocket [chemical binding]; other site
679897002808	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
679897002809	active site
679897002810	HMMPfam hit to PF00697, PRAI, score 2.5e-18
679897002811	HMMPfam hit to PF00218, IGPS, score 2.6e-31
679897002812	PS00614 Indole-3-glycerol phosphate synthase signature.
679897002813	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
679897002814	HMMPfam hit to PF01313, Bac_export_3, score 5.3e-37
679897002815	Signal peptide predicted for HMU05780 by SignalP 2.0 HMM (Signal peptide probability 0.960) with cleavage site probability 0.732 between residues 34 and 35
679897002816	2 probable transmembrane helices predicted for HMU05780 by TMHMM2.0 at aa 10-32 and 45-64
679897002817	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13904
679897002818	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
679897002819	HMMPfam hit to PF02873, MurB_C, score 2.9e-31
679897002820	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
679897002821	Signal peptide predicted for HMU05800 by SignalP 2.0 HMM (Signal peptide probability 0.983) with cleavage site probability 0.682 between residues 32 and 33
679897002822	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
679897002823	active site 1 [active]
679897002824	dimer interface [polypeptide binding]; other site
679897002825	hexamer interface [polypeptide binding]; other site
679897002826	active site 2 [active]
679897002827	HMMPfam hit to PF01361, Tautomerase, score 3.4e-13
679897002828	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
679897002829	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
679897002830	HMMPfam hit to PF02606, LpxK, score 4.8e-85
679897002831	PS00136 serine proteases, subtilase family, aspartic acid active site.
679897002832	Signal peptide predicted for HMU05820 by SignalP 2.0 HMM (Signal peptide probability 0.855) with cleavage site probability 0.845 between residues 37 and 38
679897002833	1 probable transmembrane helix predicted for HMU05820 by TMHMM2.0 at aa 13-35
679897002834	NAD synthetase; Provisional; Region: PRK13980
679897002835	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
679897002836	homodimer interface [polypeptide binding]; other site
679897002837	NAD binding pocket [chemical binding]; other site
679897002838	ATP binding pocket [chemical binding]; other site
679897002839	Mg binding site [ion binding]; other site
679897002840	active-site loop [active]
679897002841	HMMPfam hit to PF02540, NAD_synthase, score 4e-81
679897002842	flagellin A; Reviewed; Region: PRK12584
679897002843	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
679897002844	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
679897002845	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
679897002846	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
679897002847	HMMPfam hit to PF00669, Flagellin_N, score 2.1e-67
679897002848	HMMPfam hit to PF07196, Flagellin_IN, score 1.6e-08
679897002849	HMMPfam hit to PF07196, Flagellin_IN, score 1e-10
679897002850	HMMPfam hit to PF00700, Flagellin_C, score 1.2e-35
679897002851	3-methyladenine DNA glycosylase; Provisional; Region: PRK13913
679897002852	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
679897002853	minor groove reading motif; other site
679897002854	helix-hairpin-helix signature motif; other site
679897002855	active site
679897002856	HMMPfam hit to PF00730, HhH-GPD, score 3.7e-08
679897002857	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
679897002858	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
679897002859	metal binding site [ion binding]; metal-binding site
679897002860	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
679897002861	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
679897002862	CoA-binding site [chemical binding]; other site
679897002863	ATP-binding [chemical binding]; other site
679897002864	HMMPfam hit to PF01121, CoaE, score 2.4e-46
679897002865	PS00017 ATP/GTP-binding site motif A (P-loop).
679897002866	cell division protein FtsZ; Validated; Region: PRK09330
679897002867	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
679897002868	nucleotide binding site [chemical binding]; other site
679897002869	SulA interaction site; other site
679897002870	HMMPfam hit to PF03953, Tubulin_C, score 3.1e-20
679897002871	HMMPfam hit to PF00091, Tubulin, score 5e-75
679897002872	PS01135 FtsZ protein signature 2.
679897002873	PS01134 FtsZ protein signature 1.
679897002874	cell division protein FtsA; Region: ftsA; TIGR01174
679897002875	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
679897002876	nucleotide binding site [chemical binding]; other site
679897002877	SHS2 domain inserted in FTSA; Region: SHS2_FTSA; pfam02491
679897002878	Cell division protein FtsA; Region: FtsA; pfam14450
679897002879	HMMPfam hit to PF02491, FtsA, score 8.6e-19
679897002880	HMMPfam hit to PF02491, FtsA, score 7.3e-49
679897002881	SurA N-terminal domain; Region: SurA_N_3; cl07813
679897002882	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
679897002883	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
679897002884	Signal peptide predicted for HMU05900 by SignalP 2.0 HMM (Signal peptide probability 0.950) with cleavage site probability 0.751 between residues 39 and 40
679897002885	1 probable transmembrane helix predicted for HMU05900 by TMHMM2.0 at aa 12-31
679897002886	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
679897002887	putative nucleotide binding site [chemical binding]; other site
679897002888	uridine monophosphate binding site [chemical binding]; other site
679897002889	homohexameric interface [polypeptide binding]; other site
679897002890	HMMPfam hit to PF00696, AA_kinase, score 3.2e-61
679897002891	PS01039 Bacterial extracellular solute-binding proteins, family 3 signature.
679897002892	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
679897002893	HMMPfam hit to PF01192, RNA_pol_Rpb6, score 9.2e-09
679897002894	(p)ppGpp synthetase, RelA/SpoT family; Region: spoT_relA; TIGR00691
679897002895	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
679897002896	Zn2+ binding site [ion binding]; other site
679897002897	Mg2+ binding site [ion binding]; other site
679897002898	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
679897002899	synthetase active site [active]
679897002900	NTP binding site [chemical binding]; other site
679897002901	metal binding site [ion binding]; metal-binding site
679897002902	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
679897002903	HMMPfam hit to PF01966, HD, score 2.4e-09
679897002904	HMMPfam hit to PF04607, RelA_SpoT, score 1.1e-45
679897002905	HMMPfam hit to PF02824, TGS, score 1.1e-17
679897002906	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
679897002907	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
679897002908	active site
679897002909	HIGH motif; other site
679897002910	dimer interface [polypeptide binding]; other site
679897002911	KMSKS motif; other site
679897002912	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
679897002913	RNA binding surface [nucleotide binding]; other site
679897002914	HMMPfam hit to PF00579, tRNA-synt_1b, score 1.8e-109
679897002915	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
679897002916	HMMPfam hit to PF01479, S4, score 2e-06
679897002917	Nitronate monooxygenase; Region: NMO; pfam03060
679897002918	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
679897002919	FMN binding site [chemical binding]; other site
679897002920	substrate binding site [chemical binding]; other site
679897002921	putative catalytic residue [active]
679897002922	HMMPfam hit to PF03060, NPD, score 9.3e-118
679897002923	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
679897002924	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
679897002925	active site
679897002926	metal binding site [ion binding]; metal-binding site
679897002927	HMMPfam hit to PF01520, Amidase_3, score 2.6e-76
679897002928	Menaquinone biosynthesis; Region: VitK2_biosynth; pfam02621
679897002929	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
679897002930	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
679897002931	Walker A/P-loop; other site
679897002932	ATP binding site [chemical binding]; other site
679897002933	Q-loop/lid; other site
679897002934	ABC transporter signature motif; other site
679897002935	Walker B; other site
679897002936	D-loop; other site
679897002937	H-loop/switch region; other site
679897002938	ABC transporter; Region: ABC_tran_2; pfam12848
679897002939	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
679897002940	HMMPfam hit to PF00005, ABC_tran, score 4.5e-45
679897002941	PS00017 ATP/GTP-binding site motif A (P-loop).
679897002942	PS00211 ABC transporters family signature.
679897002943	HMMPfam hit to PF00005, ABC_tran, score 7.1e-37
679897002944	PS00017 ATP/GTP-binding site motif A (P-loop).
679897002945	PS00211 ABC transporters family signature.
679897002946	PAS domain; Region: PAS_9; pfam13426
679897002947	PAS domain; Region: PAS_9; pfam13426
679897002948	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
679897002949	putative active site [active]
679897002950	heme pocket [chemical binding]; other site
679897002951	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
679897002952	dimer interface [polypeptide binding]; other site
679897002953	putative CheW interface [polypeptide binding]; other site
679897002954	HMMPfam hit to PF08447, PAS_3, score 9.9e-22
679897002955	HMMPfam hit to PF00015, MCPsignal, score 1.3e-40
679897002956	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
679897002957	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
679897002958	putative active site; other site
679897002959	catalytic triad [active]
679897002960	putative dimer interface [polypeptide binding]; other site
679897002961	HMMPfam hit to PF00795, CN_hydrolase, score 2.5e-53
679897002962	Predicted permease [General function prediction only]; Region: COG2056
679897002963	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
679897002964	Signal peptide predicted for HMU06020 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.710 between residues 33 and 34
679897002965	10 probable transmembrane helices predicted for HMU06020 by TMHMM2.0 at aa 21-43, 63-81, 102-124, 144-166, 187-209, 247-269, 290-312, 327-349, 361-383 and 413-435
679897002966	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002967	HMMPfam hit to PF03553, Na_H_antiporter, score 5.8e-68
679897002968	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
679897002969	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
679897002970	HMMPfam hit to PF01312, Bac_export_2, score 4.7e-101
679897002971	5 probable transmembrane helices predicted for HMU06030 by TMHMM2.0 at aa 31-53, 58-80, 87-109, 143-165 and 186-208
679897002972	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
679897002973	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
679897002974	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
679897002975	GTP binding site; other site
679897002976	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
679897002977	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
679897002978	FeS/SAM binding site; other site
679897002979	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
679897002980	HMMPfam hit to PF04055, Radical_SAM, score 1.3e-37
679897002981	PS01305 moaA / nifB / pqqE family signature.
679897002982	HMMPfam hit to PF06463, Mob_synth_C, score 9.3e-37
679897002983	hypothetical protein; Provisional; Region: PRK08444
679897002984	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
679897002985	FeS/SAM binding site; other site
679897002986	HMMPfam hit to PF04055, Radical_SAM, score 3.6e-16
679897002987	hypothetical protein; Provisional; Region: PRK04081
679897002988	Signal peptide predicted for HMU06070 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.445 between residues 40 and 41
679897002989	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897002990	1 probable transmembrane helix predicted for HMU06070 by TMHMM2.0 at aa 110-132
679897002991	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
679897002992	HMMPfam hit to PF03738, GSP_synth, score 8.9e-202
679897002993	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
679897002994	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
679897002995	active site
679897002996	HMMPfam hit to PF00535, Glycos_transf_2, score 6.7e-39
679897002997	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
679897002998	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
679897002999	11 probable transmembrane helices predicted for HMU06100 by TMHMM2.0 at aa 9-31, 51-73, 86-108, 123-145, 152-174, 184-206, 227-249, 264-283, 304-326, 341-363 and 375-408
679897003000	HMMPfam hit to PF01554, MatE, score 7.2e-10
679897003001	HMMPfam hit to PF01554, MatE, score 1.2e-17
679897003002	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897003003	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
679897003004	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
679897003005	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
679897003006	14 probable transmembrane helices predicted for HMU06110 by TMHMM2.0 at aa 27-49, 54-76, 85-107, 111-133, 146-168, 172-194, 224-246, 256-275, 287-304, 333-355, 368-390, 400-422, 434-456 and 466-485
679897003007	PS01022 PTR2 family proton/oligopeptide symporters signature 1.
679897003008	HMMPfam hit to PF00854, PTR2, score 1.1e-37
679897003009	PS01023 PTR2 family proton/oligopeptide symporters signature 2.
679897003010	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897003011	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
679897003012	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
679897003013	HMMPfam hit to PF08425, NiFe_dehyd_N, score 2.3e-14
679897003014	HMMPfam hit to PF01058, Oxidored_q6, score 9.4e-05
679897003015	Alpha-2,3-sialyltransferase (CST-I); Region: CST-I; pfam06002
679897003016	HMMPfam hit to PF06002, CST-I, score 6.3e-64
679897003017	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
679897003018	ligand binding site; other site
679897003019	tetramer interface; other site
679897003020	HMMPfam hit to PF02348, CTP_transf_3, score 1.2e-29
679897003021	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
679897003022	NeuB family; Region: NeuB; pfam03102
679897003023	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
679897003024	NeuB binding interface [polypeptide binding]; other site
679897003025	putative substrate binding site [chemical binding]; other site
679897003026	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
679897003027	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
679897003028	active site
679897003029	homodimer interface [polypeptide binding]; other site
679897003030	HMMPfam hit to PF02350, Epimerase_2, score 2.3e-88
679897003031	HMMPfam hit to PF08666, SAF, score 1.5e-09
679897003032	HMMPfam hit to PF03102, NeuB, score 1.7e-96
679897003033	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
679897003034	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897003035	S-adenosylmethionine binding site [chemical binding]; other site
679897003036	Protein of unknown function (DUF452); Region: DUF452; cl01062
679897003037	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
679897003038	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
679897003039	inhibitor-cofactor binding pocket; inhibition site
679897003040	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897003041	catalytic residue [active]
679897003042	HMMPfam hit to PF00202, Aminotran_3, score 3.6e-115
679897003043	PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site.
679897003044	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897003045	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
679897003046	AAA domain; Region: AAA_26; pfam13500
679897003047	PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature.
679897003048	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
679897003049	dimer interface [polypeptide binding]; other site
679897003050	substrate binding site [chemical binding]; other site
679897003051	metal binding sites [ion binding]; metal-binding site
679897003052	HMMPfam hit to PF00719, Pyrophosphatase, score 2.4e-61
679897003053	PS00387 Inorganic pyrophosphatase signature.
679897003054	adenylate kinase; Reviewed; Region: adk; PRK00279
679897003055	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
679897003056	AMP-binding site [chemical binding]; other site
679897003057	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
679897003058	HMMPfam hit to PF00406, ADK, score 4.1e-27
679897003059	PS00113 Adenylate kinase signature.
679897003060	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003061	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
679897003062	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
679897003063	dimer interface [polypeptide binding]; other site
679897003064	anticodon binding site; other site
679897003065	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
679897003066	homodimer interface [polypeptide binding]; other site
679897003067	motif 1; other site
679897003068	active site
679897003069	motif 2; other site
679897003070	GAD domain; Region: GAD; pfam02938
679897003071	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
679897003072	active site
679897003073	motif 3; other site
679897003074	HMMPfam hit to PF00152, tRNA-synt_2, score 5.4e-205
679897003075	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
679897003076	HMMPfam hit to PF02938, GAD, score 1.7e-30
679897003077	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
679897003078	HMMPfam hit to PF01336, tRNA_anti, score 1.1e-24
679897003079	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
679897003080	Response regulator receiver domain; Region: Response_reg; pfam00072
679897003081	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
679897003082	active site
679897003083	phosphorylation site [posttranslational modification]
679897003084	intermolecular recognition site; other site
679897003085	HMMPfam hit to PF00072, Response_reg, score 1.3e-17
679897003086	HMMPfam hit to PF01584, CheW, score 8.1e-18
679897003087	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
679897003088	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
679897003089	Heavy-metal-associated domain; Region: HMA; pfam00403
679897003090	metal-binding site [ion binding]
679897003091	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
679897003092	Soluble P-type ATPase [General function prediction only]; Region: COG4087
679897003093	7 probable transmembrane helices predicted for HMU06250 by TMHMM2.0 at aa 175-197, 212-234, 246-265, 270-288, 422-444, 459-481 and 755-777
679897003094	HMMPfam hit to PF00702, Hydrolase, score 9.6e-20
679897003095	PS00154 E1-E2 ATPases phosphorylation site.
679897003096	HMMPfam hit to PF00122, E1-E2_ATPase, score 5.4e-44
679897003097	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897003098	HMMPfam hit to PF00403, HMA, score 0.001
679897003099	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
679897003100	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897003101	S-adenosylmethionine binding site [chemical binding]; other site
679897003102	HMMPfam hit to PF05175, MTS, score 3.6e-07
679897003103	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
679897003104	PS00092 N-6 Adenine-specific DNA methylases signature.
679897003105	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
679897003106	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
679897003107	catalytic motif [active]
679897003108	Zn binding site [ion binding]; other site
679897003109	RibD C-terminal domain; Region: RibD_C; cl17279
679897003110	HMMPfam hit to PF00383, dCMP_cyt_deam_1, score 2e-25
679897003111	Signal peptide predicted for HMU06280 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.587 between residues 24 and 25
679897003112	Heme-binding domain of the class III cytochrome C family and related proteins; Region: Cytochrom_C3; cl03439
679897003113	heme-binding residues [chemical binding]; other site
679897003114	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897003115	PS00190 Cytochrome c family heme-binding site signature.
679897003116	PS00190 Cytochrome c family heme-binding site signature.
679897003117	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
679897003118	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
679897003119	HMMPfam hit to PF07992, Pyr_redox_2, score 8.2e-08
679897003120	HMMPfam hit to PF00070, Pyr_redox, score 2.3e-09
679897003121	HMMPfam hit to PF03597, CcoS, score 9.1e-09
679897003122	1 probable transmembrane helix predicted for HMU06350 by TMHMM2.0 at aa 2-20
679897003123	Maf-like protein; Reviewed; Region: PRK04056
679897003124	Maf-like protein; Region: Maf; pfam02545
679897003125	putative active site [active]
679897003126	HMMPfam hit to PF02545, Maf, score 1.7e-33
679897003127	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
679897003128	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
679897003129	motif 1; other site
679897003130	active site
679897003131	motif 2; other site
679897003132	motif 3; other site
679897003133	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
679897003134	DHHA1 domain; Region: DHHA1; pfam02272
679897003135	HMMPfam hit to PF02272, DHHA1, score 5.4e-13
679897003136	HMMPfam hit to PF07973, tRNA_SAD, score 1.2e-19
679897003137	HMMPfam hit to PF01411, tRNA-synt_2c, score 6.7e-277
679897003138	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
679897003139	NifU-like domain; Region: NifU; pfam01106
679897003140	HMMPfam hit to PF01106, NifU, score 6.8e-27
679897003141	HMMPfam hit to PF07719, TPR_2, score 0.00026
679897003142	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
679897003143	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
679897003144	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
679897003145	HMMPfam hit to PF08245, Mur_ligase_M, score 2e-56
679897003146	PS01011 Folylpolyglutamate synthase signature 1.
679897003147	HMMPfam hit to PF02875, Mur_ligase_C, score 2.2e-23
679897003148	PS00294 Prenyl group binding site (CAAX box).
679897003149	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
679897003150	dimerization interface [polypeptide binding]; other site
679897003151	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
679897003152	ATP binding site [chemical binding]; other site
679897003153	HMMPfam hit to PF00586, AIRS, score 2e-18
679897003154	HMMPfam hit to PF02769, AIRS_C, score 4.4e-26
679897003155	dihydroorotase; Provisional; Region: PRK05451
679897003156	active site
679897003157	PS00483 Dihydroorotase signature 2.
679897003158	PS00482 Dihydroorotase signature 1.
679897003159	Cytochrome c; Region: Cytochrom_C; pfam00034
679897003160	PS00190 Cytochrome c family heme-binding site signature.
679897003161	Signal peptide predicted for HMU06440 by SignalP 2.0 HMM (Signal peptide probability 0.811) with cleavage site probability 0.371 between residues 16 and 17
679897003162	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14191
679897003163	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
679897003164	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
679897003165	homodimer interface [polypeptide binding]; other site
679897003166	NADP binding site [chemical binding]; other site
679897003167	substrate binding site [chemical binding]; other site
679897003168	HMMPfam hit to PF00763, THF_DHG_CYH, score 6.7e-57
679897003169	PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1.
679897003170	HMMPfam hit to PF02882, THF_DHG_CYH_C, score 1.6e-99
679897003171	PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2.
679897003172	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
679897003173	Catalytic site [active]
679897003174	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
679897003175	Catalytic site [active]
679897003176	Signal peptide predicted for HMU06460 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.550 between residues 34 and 35
679897003177	1 probable transmembrane helix predicted for HMU06460 by TMHMM2.0 at aa 13-35
679897003178	HMMPfam hit to PF00717, Peptidase_S24, score 1.3e-10
679897003179	PS00761 Signal peptidases I signature 3.
679897003180	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
679897003181	Peptidase family M50; Region: Peptidase_M50; pfam02163
679897003182	active site
679897003183	putative substrate binding region [chemical binding]; other site
679897003184	5 probable transmembrane helices predicted for HMU06470 by TMHMM2.0 at aa 7-29, 57-79, 98-120, 135-157 and 188-210
679897003185	HMMPfam hit to PF02163, Peptidase_M50, score 3.6e-29
679897003186	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
679897003187	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
679897003188	HMMPfam hit to PF02502, LacAB_rpiB, score 4.8e-67
679897003189	PS00237 G-protein coupled receptors signature.
679897003190	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
679897003191	1 probable transmembrane helix predicted for HMU06490 by TMHMM2.0 at aa 6-28
679897003192	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
679897003193	active site
679897003194	HMMPfam hit to PF00156, Pribosyltran, score 6.5e-39
679897003195	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
679897003196	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
679897003197	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
679897003198	Signal peptide predicted for HMU06510 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.577 between residues 23 and 24
679897003199	6 probable transmembrane helices predicted for HMU06510 by TMHMM2.0 at aa 5-23, 45-67, 74-96, 116-138, 159-181 and 196-213
679897003200	multifunctional aminopeptidase A; Provisional; Region: PRK00913
679897003201	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
679897003202	interface (dimer of trimers) [polypeptide binding]; other site
679897003203	Substrate-binding/catalytic site; other site
679897003204	Zn-binding sites [ion binding]; other site
679897003205	HMMPfam hit to PF02789, Peptidase_M17_N, score 1.2e-06
679897003206	HMMPfam hit to PF00883, Peptidase_M17, score 3.5e-160
679897003207	PS00631 Cytosol aminopeptidase signature.
679897003208	GTP-binding protein YchF; Reviewed; Region: PRK09601
679897003209	YchF GTPase; Region: YchF; cd01900
679897003210	G1 box; other site
679897003211	GTP/Mg2+ binding site [chemical binding]; other site
679897003212	Switch I region; other site
679897003213	G2 box; other site
679897003214	Switch II region; other site
679897003215	G3 box; other site
679897003216	G4 box; other site
679897003217	G5 box; other site
679897003218	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
679897003219	HMMPfam hit to PF01926, MMR_HSR1, score 1.3e-36
679897003220	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003221	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
679897003222	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
679897003223	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
679897003224	HMMPfam hit to PF01075, Glyco_transf_9, score 0.00019
679897003225	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
679897003226	This family is most closely related to the GT1 family of glycosyltransferases. wcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis; Region: GT1_wcfI_like; cd03825
679897003227	HMMPfam hit to PF00534, Glycos_transf_1, score 6.2e-15
679897003228	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
679897003229	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
679897003230	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
679897003231	nucleotide binding site [chemical binding]; other site
679897003232	NEF interaction site [polypeptide binding]; other site
679897003233	SBD interface [polypeptide binding]; other site
679897003234	HMMPfam hit to PF00012, HSP70, score 0
679897003235	PS01036 Heat shock hsp70 proteins family signature 3.
679897003236	PS00329 Heat shock hsp70 proteins family signature 2.
679897003237	PS00297 Heat shock hsp70 proteins family signature 1.
679897003238	GrpE; Region: GrpE; pfam01025
679897003239	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
679897003240	dimer interface [polypeptide binding]; other site
679897003241	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
679897003242	HMMPfam hit to PF01025, GrpE, score 2.3e-50
679897003243	heat-inducible transcription repressor; Provisional; Region: PRK03911
679897003244	UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677
679897003245	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
679897003246	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
679897003247	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
679897003248	HMMPfam hit to PF03720, UDPG_MGDP_dh_C, score 1.4e-14
679897003249	HMMPfam hit to PF00984, UDPG_MGDP_dh, score 1.8e-36
679897003250	HMMPfam hit to PF03721, UDPG_MGDP_dh_N, score 1.4e-51
679897003251	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
679897003252	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
679897003253	inhibitor-cofactor binding pocket; inhibition site
679897003254	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897003255	catalytic residue [active]
679897003256	HMMPfam hit to PF01041, DegT_DnrJ_EryC1, score 1.7e-131
679897003257	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
679897003258	putative trimer interface [polypeptide binding]; other site
679897003259	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
679897003260	putative CoA binding site [chemical binding]; other site
679897003261	putative trimer interface [polypeptide binding]; other site
679897003262	putative active site [active]
679897003263	putative substrate binding site [chemical binding]; other site
679897003264	putative CoA binding site [chemical binding]; other site
679897003265	HMMPfam hit to PF00132, Hexapep, score 34
679897003266	HMMPfam hit to PF00132, Hexapep, score 22
679897003267	HMMPfam hit to PF00132, Hexapep, score 44
679897003268	HMMPfam hit to PF00132, Hexapep, score 0.012
679897003269	HMMPfam hit to PF00132, Hexapep, score 0.015
679897003270	HMMPfam hit to PF00132, Hexapep, score 0.077
679897003271	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
679897003272	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
679897003273	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
679897003274	HMMPfam hit to PF02894, GFO_IDH_MocA_C, score 1.4e-06
679897003275	HMMPfam hit to PF01408, GFO_IDH_MocA, score 1.4e-17
679897003276	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
679897003277	active site
679897003278	UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350
679897003279	homodimer interface [polypeptide binding]; other site
679897003280	HMMPfam hit to PF02350, Epimerase_2, score 7.1e-79
679897003281	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
679897003282	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_4; cd03795
679897003283	putative ADP-binding pocket [chemical binding]; other site
679897003284	HMMPfam hit to PF00534, Glycos_transf_1, score 1e-35
679897003285	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
679897003286	Autotransporter beta-domain; Region: Autotransporter; cl17461
679897003287	HMMPfam hit to PF03077, VacA2, score 2.7e-22
679897003288	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003289	HMMPfam hit to PF03797, Autotransporter, score 1.6e-10
679897003290	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
679897003291	HMMPfam hit to PF03797, Autotransporter, score 4.4e-12
679897003292	PS00881 Protein splicing signature.
679897003293	PS00881 Protein splicing signature.
679897003294	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003295	HMMPfam hit to PF03077, VacA2, score 2.7e-22
679897003296	Signal peptide predicted for HMU06730 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.729 between residues 33 and 34
679897003297	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
679897003298	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
679897003299	Autotransporter beta-domain; Region: Autotransporter; pfam03797
679897003300	HMMPfam hit to PF03797, Autotransporter, score 0.00012
679897003301	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
679897003302	Signal peptide predicted for HMU06740 by SignalP 2.0 HMM (Signal peptide probability 0.802) with cleavage site probability 0.570 between residues 63 and 64
679897003303	1 probable transmembrane helix predicted for HMU06740 by TMHMM2.0 at aa 31-53
679897003304	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
679897003305	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
679897003306	HMMPfam hit to PF01118, Semialdhyde_dh, score 6.6e-40
679897003307	HMMPfam hit to PF02774, Semialdhyde_dhC, score 3.4e-72
679897003308	PS01103 Aspartate-semialdehyde dehydrogenase signature.
679897003309	Domain of unknown function (DUF386); Region: DUF386; cl01047
679897003310	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
679897003311	dimerization interface [polypeptide binding]; other site
679897003312	active site
679897003313	HMMPfam hit to PF00925, GTP_cyclohydro2, score 3.1e-75
679897003314	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
679897003315	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
679897003316	dimer interface [polypeptide binding]; other site
679897003317	putative functional site; other site
679897003318	putative MPT binding site; other site
679897003319	HMMPfam hit to PF03453, MoeA_N, score 1.1e-32
679897003320	HMMPfam hit to PF00994, MoCF_biosynth, score 1.6e-44
679897003321	PS01079 Molybdenum cofactor biosynthesis proteins signature 2.
679897003322	HMMPfam hit to PF03454, MoeA_C, score 0.00011
679897003323	charged pocket; other site
679897003324	ThiS family; Region: ThiS; pfam02597
679897003325	hydrophobic patch; other site
679897003326	HMMPfam hit to PF02597, ThiS, score 0.00015
679897003327	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
679897003328	MoaE homodimer interface [polypeptide binding]; other site
679897003329	MoaD interaction [polypeptide binding]; other site
679897003330	active site residues [active]
679897003331	HMMPfam hit to PF02391, MoaE, score 0.0001
679897003332	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
679897003333	MPT binding site; other site
679897003334	trimer interface [polypeptide binding]; other site
679897003335	HMMPfam hit to PF00994, MoCF_biosynth, score 2.4e-34
679897003336	PS01078 Molybdenum cofactor biosynthesis proteins signature 1.
679897003337	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
679897003338	trimer interface [polypeptide binding]; other site
679897003339	dimer interface [polypeptide binding]; other site
679897003340	putative active site [active]
679897003341	HMMPfam hit to PF01967, MoaC, score 1.9e-77
679897003342	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
679897003343	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
679897003344	GIY-YIG motif/motif A; other site
679897003345	active site
679897003346	catalytic site [active]
679897003347	putative DNA binding site [nucleotide binding]; other site
679897003348	metal binding site [ion binding]; metal-binding site
679897003349	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
679897003350	HMMPfam hit to PF08459, UvrC_HhH_N, score 4.6e-52
679897003351	HMMPfam hit to PF02151, UVR, score 0.0017
679897003352	HMMPfam hit to PF01541, GIY-YIG, score 5.7e-24
679897003353	Predicted membrane protein [Function unknown]; Region: COG1289
679897003354	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
679897003355	12 probable transmembrane helices predicted for HMU06850 by TMHMM2.0 at aa 20-42, 47-69, 81-103, 108-127, 134-156, 161-180, 364-381, 391-408, 415-432, 436-453, 460-482 and 487-506
679897003356	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897003357	Uncharacterized conserved protein [Function unknown]; Region: COG1432
679897003358	Uncharacterized subfamily of N-terminal LabA-like domains; Region: LabA_like_N_1; cd11297
679897003359	putative metal binding site [ion binding]; other site
679897003360	C-terminal domain of LabA_like proteins; Region: LabA_like_C; cd10146
679897003361	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK08412
679897003362	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
679897003363	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
679897003364	HMMPfam hit to PF00669, Flagellin_N, score 0.00094
679897003365	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
679897003366	homotrimer interaction site [polypeptide binding]; other site
679897003367	putative active site [active]
679897003368	HMMPfam hit to PF01042, Ribonuc_L-PSP, score 4.8e-62
679897003369	PS01094 Uncharacterized protein family UPF0076 signature.
679897003370	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
679897003371	HMMPfam hit to PF00829, Ribosomal_L21p, score 3.8e-48
679897003372	PS01169 Ribosomal protein L21 signature.
679897003373	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
679897003374	HMMPfam hit to PF01016, Ribosomal_L27, score 6.9e-56
679897003375	PS00831 Ribosomal protein L27 signature.
679897003376	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
679897003377	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
679897003378	dimer interface [polypeptide binding]; other site
679897003379	conserved gate region; other site
679897003380	putative PBP binding loops; other site
679897003381	ABC-ATPase subunit interface; other site
679897003382	Signal peptide predicted for HMU06910 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.938 between residues 41 and 42
679897003383	6 probable transmembrane helices predicted for HMU06910 by TMHMM2.0 at aa 20-42, 137-159, 180-199, 203-222, 253-275 and 309-331
679897003384	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
679897003385	HMMPfam hit to PF00528, BPD_transp_1, score 6.2e-40
679897003386	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
679897003387	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
679897003388	Walker A/P-loop; other site
679897003389	ATP binding site [chemical binding]; other site
679897003390	Q-loop/lid; other site
679897003391	ABC transporter signature motif; other site
679897003392	Walker B; other site
679897003393	D-loop; other site
679897003394	H-loop/switch region; other site
679897003395	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
679897003396	Walker A/P-loop; other site
679897003397	ATP binding site [chemical binding]; other site
679897003398	Q-loop/lid; other site
679897003399	ABC transporter signature motif; other site
679897003400	Walker B; other site
679897003401	D-loop; other site
679897003402	H-loop/switch region; other site
679897003403	HMMPfam hit to PF00005, ABC_tran, score 3.1e-48
679897003404	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003405	HMMPfam hit to PF00005, ABC_tran, score 8.2e-47
679897003406	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003407	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
679897003408	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897003409	Predicted methyltransferases [General function prediction only]; Region: COG0313
679897003410	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
679897003411	putative SAM binding site [chemical binding]; other site
679897003412	putative homodimer interface [polypeptide binding]; other site
679897003413	HMMPfam hit to PF00590, TP_methylase, score 2.8e-10
679897003414	PS01296 Uncharacterized protein family UPF0011 signature.
679897003415	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
679897003416	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
679897003417	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
679897003418	HMMPfam hit to PF08032, SpoU_sub_bind, score 3.7e-09
679897003419	HMMPfam hit to PF00588, SpoU_methylase, score 4.7e-38
679897003420	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
679897003421	1 probable transmembrane helix predicted for HMU06960 by TMHMM2.0 at aa 102-124
679897003422	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
679897003423	11 probable transmembrane helices predicted for HMU06980 by TMHMM2.0 at aa 21-43, 53-75, 80-97, 102-124, 136-158, 173-207, 235-252, 315-337, 339-361, 376-407 and 414-431
679897003424	HMMPfam hit to PF00860, Xan_ur_permease, score 4.7e-09
679897003425	Signal peptide predicted for HMU06980 by SignalP 2.0 HMM (Signal peptide probability 0.956) with cleavage site probability 0.909 between residues 39 and 40
679897003426	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
679897003427	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
679897003428	putative active site [active]
679897003429	putative metal binding site [ion binding]; other site
679897003430	HMMPfam hit to PF00149, Metallophos, score 1.4e-16
679897003431	3 probable transmembrane helices predicted for HMU06990 by TMHMM2.0 at aa 17-39, 54-76 and 83-105
679897003432	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
679897003433	Low molecular weight phosphatase family; Region: LMWPc; cd00115
679897003434	active site
679897003435	HMMPfam hit to PF01451, LMWPc, score 1.1e-42
679897003436	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
679897003437	Signal peptide predicted for HMU07010 by SignalP 2.0 HMM (Signal peptide probability 0.862) with cleavage site probability 0.434 between residues 30 and 31
679897003438	1 probable transmembrane helix predicted for HMU07010 by TMHMM2.0 at aa 7-25
679897003439	PS00190 Cytochrome c family heme-binding site signature.
679897003440	antiporter inner membrane protein; Provisional; Region: PRK11670
679897003441	Domain of unknown function DUF59; Region: DUF59; cl00941
679897003442	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
679897003443	HMMPfam hit to PF01656, CbiA, score 1.6e-12
679897003444	PS01215 Mrp family signature.
679897003445	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003446	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
679897003447	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
679897003448	putative active site [active]
679897003449	PhoH-like protein; Region: PhoH; pfam02562
679897003450	HMMPfam hit to PF02562, PhoH, score 1.8e-11
679897003451	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003452	Protein of unknown function DUF45; Region: DUF45; pfam01863
679897003453	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
679897003454	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
679897003455	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
679897003456	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
679897003457	HMMPfam hit to PF01281, Ribosomal_L9_N, score 2.2e-21
679897003458	PS00651 Ribosomal protein L9 signature.
679897003459	HMMPfam hit to PF03948, Ribosomal_L9_C, score 8.3e-20
679897003460	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
679897003461	active site
679897003462	HslU subunit interaction site [polypeptide binding]; other site
679897003463	HMMPfam hit to PF00227, Proteasome, score 8.4e-21
679897003464	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
679897003465	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897003466	Walker A motif; other site
679897003467	ATP binding site [chemical binding]; other site
679897003468	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897003469	Walker B motif; other site
679897003470	arginine finger; other site
679897003471	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
679897003472	HMMPfam hit to PF07724, AAA_2, score 4.8e-42
679897003473	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003474	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003475	GTPase Era; Reviewed; Region: era; PRK00089
679897003476	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
679897003477	G1 box; other site
679897003478	GTP/Mg2+ binding site [chemical binding]; other site
679897003479	Switch I region; other site
679897003480	G2 box; other site
679897003481	Switch II region; other site
679897003482	G3 box; other site
679897003483	G4 box; other site
679897003484	G5 box; other site
679897003485	KH domain; Region: KH_2; pfam07650
679897003486	HMMPfam hit to PF01926, MMR_HSR1, score 1.3e-34
679897003487	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003488	HMMPfam hit to PF07650, KH_2, score 1.6e-16
679897003489	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
679897003490	Signal peptide predicted for HMU07090 by SignalP 2.0 HMM (Signal peptide probability 0.940) with cleavage site probability 0.515 between residues 23 and 24
679897003491	KAP family P-loop domain; Region: KAP_NTPase; pfam07693
679897003492	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
679897003493	HMMPfam hit to PF07693, KAP_NTPase, score 3e-05
679897003494	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003495	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
679897003496	FeS/SAM binding site; other site
679897003497	HMMPfam hit to PF04055, Radical_SAM, score 1.1e-09
679897003498	DNA topoisomerase I; Validated; Region: PRK05582
679897003499	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
679897003500	active site
679897003501	interdomain interaction site; other site
679897003502	putative metal-binding site [ion binding]; other site
679897003503	nucleotide binding site [chemical binding]; other site
679897003504	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
679897003505	domain I; other site
679897003506	DNA binding groove [nucleotide binding]
679897003507	phosphate binding site [ion binding]; other site
679897003508	domain II; other site
679897003509	domain III; other site
679897003510	nucleotide binding site [chemical binding]; other site
679897003511	catalytic site [active]
679897003512	domain IV; other site
679897003513	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
679897003514	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
679897003515	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
679897003516	HMMPfam hit to PF01396, zf-C4_Topoisom, score 3.2e-18
679897003517	HMMPfam hit to PF01396, zf-C4_Topoisom, score 2.9e-16
679897003518	HMMPfam hit to PF01396, zf-C4_Topoisom, score 1.2e-14
679897003519	HMMPfam hit to PF01131, Topoisom_bac, score 1.2e-168
679897003520	PS00396 Prokaryotic DNA topoisomerase I active site.
679897003521	HMMPfam hit to PF01751, Toprim, score 9.1e-31
679897003522	flagellin B; Provisional; Region: PRK13588
679897003523	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
679897003524	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
679897003525	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
679897003526	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
679897003527	HMMPfam hit to PF00669, Flagellin_N, score 4.5e-72
679897003528	HMMPfam hit to PF07196, Flagellin_IN, score 1.8e-09
679897003529	HMMPfam hit to PF07196, Flagellin_IN, score 8.6e-10
679897003530	HMMPfam hit to PF00700, Flagellin_C, score 1.3e-38
679897003531	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
679897003532	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
679897003533	ArsC family; Region: ArsC; pfam03960
679897003534	HMMPfam hit to PF03960, ArsC, score 2.6e-35
679897003535	NLPC_P60 stabilising domain, N term; Region: N_NLPC_P60; pfam12912
679897003536	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
679897003537	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
679897003538	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
679897003539	NlpC/P60 family; Region: NLPC_P60; cl17555
679897003540	Signal peptide predicted for HMU07180 by SignalP 2.0 HMM (Signal peptide probability 0.985) with cleavage site probability 0.765 between residues 25 and 26
679897003541	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897003542	HMMPfam hit to PF00877, NLPC_P60, score 1.6e-11
679897003543	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
679897003544	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
679897003545	intersubunit interface [polypeptide binding]; other site
679897003546	Signal peptide predicted for HMU07190 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.540 between residues 23 and 24
679897003547	1 probable transmembrane helix predicted for HMU07190 by TMHMM2.0 at aa 5-27
679897003548	HMMPfam hit to PF01297, SBP_bac_9, score 1.4e-47
679897003549	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
679897003550	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
679897003551	HMMPfam hit to PF00005, ABC_tran, score 3.5e-47
679897003552	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003553	PS00211 ABC transporters family signature.
679897003554	Predicted dehydrogenase [General function prediction only]; Region: COG0579
679897003555	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
679897003556	HMMPfam hit to PF01266, DAO, score 3.9e-06
679897003557	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897003558	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897003559	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
679897003560	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
679897003561	dimer interface [polypeptide binding]; other site
679897003562	putative PBP binding regions; other site
679897003563	ABC-ATPase subunit  interface; other site
679897003564	Signal peptide predicted for HMU07220 by SignalP 2.0 HMM (Signal peptide probability 0.872) with cleavage site probability 0.645 between residues 35 and 36
679897003565	HMMPfam hit to PF00950, ABC-3, score 2.1e-49
679897003566	9 probable transmembrane helices predicted for HMU07220 by TMHMM2.0 at aa 10-32, 39-58, 62-84, 91-113, 133-150, 171-188, 192-214, 221-239 and 243-265
679897003567	Signal peptide predicted for HMU07230 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.785 between residues 37 and 38
679897003568	1 probable transmembrane helix predicted for HMU07230 by TMHMM2.0 at aa 13-35
679897003569	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
679897003570	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
679897003571	active site
679897003572	DNA binding site [nucleotide binding]
679897003573	Int/Topo IB signature motif; other site
679897003574	HMMPfam hit to PF00589, Phage_integrase, score 4e-24
679897003575	Class-II DAHP synthetase family; Region: DAHP_synth_2; pfam01474
679897003576	HMMPfam hit to PF01474, DAHP_synth_2, score 4e-273
679897003577	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897003578	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
679897003579	HMMPfam hit to PF02686, Glu-tRNAGln, score 6.2e-13
679897003580	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
679897003581	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
679897003582	active site
679897003583	Signal peptide predicted for HMU07280 by SignalP 2.0 HMM (Signal peptide probability 0.969) with cleavage site probability 0.894 between residues 30 and 31
679897003584	6 probable transmembrane helices predicted for HMU07280 by TMHMM2.0 at aa 2-24, 58-80, 87-109, 124-146, 158-175 and 185-207
679897003585	HMMPfam hit to PF01569, PAP2, score 1.6e-31
679897003586	Signal peptide predicted for HMU07290 by SignalP 2.0 HMM (Signal peptide probability 0.683) with cleavage site probability 0.603 between residues 39 and 40
679897003587	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
679897003588	HMMPfam hit to PF04313, HSDR_N, score 2.4e-16
679897003589	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003590	PS00092 N-6 Adenine-specific DNA methylases signature.
679897003591	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
679897003592	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
679897003593	HMMPfam hit to PF00534, Glycos_transf_1, score 6e-13
679897003594	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
679897003595	7 probable transmembrane helices predicted for HMU07340 by TMHMM2.0 at aa 10-32, 45-67, 87-104, 125-147, 162-184, 196-218 and 222-239
679897003596	HMMPfam hit to PF03741, TerC, score 1.2e-28
679897003597	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
679897003598	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
679897003599	oligomer interface [polypeptide binding]; other site
679897003600	HMMPfam hit to PF01544, CorA, score 2.3e-70
679897003601	2 probable transmembrane helices predicted for HMU07350 by TMHMM2.0 at aa 259-281 and 291-313
679897003602	Phosphoglycerate kinase; Region: PGK; pfam00162
679897003603	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
679897003604	substrate binding site [chemical binding]; other site
679897003605	hinge regions; other site
679897003606	ADP binding site [chemical binding]; other site
679897003607	catalytic site [active]
679897003608	HMMPfam hit to PF00162, PGK, score 1.4e-168
679897003609	PS00111 Phosphoglycerate kinase signature.
679897003610	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
679897003611	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
679897003612	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
679897003613	HMMPfam hit to PF02800, Gp_dh_C, score 1.8e-87
679897003614	PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site.
679897003615	HMMPfam hit to PF00044, Gp_dh_N, score 3.7e-64
679897003616	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
679897003617	IHF dimer interface [polypeptide binding]; other site
679897003618	IHF - DNA interface [nucleotide binding]; other site
679897003619	HMMPfam hit to PF00216, Bac_DNA_binding, score 7.1e-27
679897003620	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
679897003621	active site
679897003622	multimer interface [polypeptide binding]; other site
679897003623	HMMPfam hit to PF00334, NDK, score 1e-77
679897003624	PS00469 Nucleoside diphosphate kinases active site.
679897003625	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
679897003626	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
679897003627	HMMPfam hit to PF01783, Ribosomal_L32p, score 3.3e-06
679897003628	putative phosphate acyltransferase; Provisional; Region: PRK05331
679897003629	HMMPfam hit to PF02504, FA_synthesis, score 2.3e-161
679897003630	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
679897003631	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
679897003632	dimer interface [polypeptide binding]; other site
679897003633	active site
679897003634	CoA binding pocket [chemical binding]; other site
679897003635	HMMPfam hit to PF08545, ACP_syn_III, score 1.1e-43
679897003636	HMMPfam hit to PF08541, ACP_syn_III_C, score 3.8e-46
679897003637	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
679897003638	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
679897003639	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
679897003640	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
679897003641	HMMPfam hit to PF02844, GARS_N, score 8.9e-21
679897003642	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003643	HMMPfam hit to PF01071, GARS_A, score 7.4e-115
679897003644	HMMPfam hit to PF02843, GARS_C, score 7e-27
679897003645	RDD family; Region: RDD; pfam06271
679897003646	HMMPfam hit to PF06271, RDD, score 6.8e-18
679897003647	2 probable transmembrane helices predicted for HMU07450 by TMHMM2.0 at aa 26-48 and 63-85
679897003648	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
679897003649	Organic solvent tolerance protein; Region: OstA_C; pfam04453
679897003650	HMMPfam hit to PF04453, OstA_C, score 1.5e-16
679897003651	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
679897003652	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
679897003653	oligomer interface [polypeptide binding]; other site
679897003654	RNA binding site [nucleotide binding]; other site
679897003655	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
679897003656	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
679897003657	oligomer interface [polypeptide binding]; other site
679897003658	RNA binding site [nucleotide binding]; other site
679897003659	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
679897003660	RNA binding site [nucleotide binding]; other site
679897003661	domain interface; other site
679897003662	HMMPfam hit to PF01138, RNase_PH, score 1.4e-25
679897003663	HMMPfam hit to PF03725, RNase_PH_C, score 2e-11
679897003664	PS00445 FGGY family of carbohydrate kinases signature 2.
679897003665	HMMPfam hit to PF03726, PNPase, score 3.2e-06
679897003666	HMMPfam hit to PF01138, RNase_PH, score 7.5e-40
679897003667	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897003668	HMMPfam hit to PF03725, RNase_PH_C, score 2.2e-21
679897003669	HMMPfam hit to PF00013, KH_1, score 2e-11
679897003670	HMMPfam hit to PF00575, S1, score 4.3e-08
679897003671	F0F1 ATP synthase subunit C; Validated; Region: PRK08482
679897003672	Signal peptide predicted for HMU07480 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.431 between residues 52 and 53
679897003673	3 probable transmembrane helices predicted for HMU07480 by TMHMM2.0 at aa 4-26, 33-55 and 75-97
679897003674	HMMPfam hit to PF00137, ATP-synt_C, score 2.1e-14
679897003675	PS00605 ATP synthase c subunit signature.
679897003676	aspartate aminotransferase; Provisional; Region: PRK05764
679897003677	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
679897003678	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897003679	homodimer interface [polypeptide binding]; other site
679897003680	catalytic residue [active]
679897003681	HMMPfam hit to PF00155, Aminotran_1_2, score 5.3e-86
679897003682	PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site.
679897003683	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897003684	S-adenosylmethionine binding site [chemical binding]; other site
679897003685	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
679897003686	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
679897003687	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
679897003688	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
679897003689	active site
679897003690	HMMPfam hit to PF00478, IMPDH, score 3.9e-240
679897003691	PS00487 IMP dehydrogenase / GMP reductase signature.
679897003692	HMMPfam hit to PF00571, CBS, score 5.2e-31
679897003693	indole-3-acetamide amidohydrolase; Region: PLN02722
679897003694	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
679897003695	HMMPfam hit to PF01425, Amidase, score 8.3e-173
679897003696	PS00571 Amidases signature.
679897003697	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
679897003698	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897003699	Walker A motif; other site
679897003700	ATP binding site [chemical binding]; other site
679897003701	Walker B motif; other site
679897003702	arginine finger; other site
679897003703	HMMPfam hit to PF00004, AAA, score 9.7e-38
679897003704	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003705	PS00176 Eukaryotic DNA topoisomerase I active site.
679897003706	GTP-binding protein Der; Reviewed; Region: PRK00093
679897003707	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
679897003708	G1 box; other site
679897003709	GTP/Mg2+ binding site [chemical binding]; other site
679897003710	Switch I region; other site
679897003711	G2 box; other site
679897003712	Switch II region; other site
679897003713	G3 box; other site
679897003714	G4 box; other site
679897003715	G5 box; other site
679897003716	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
679897003717	G1 box; other site
679897003718	GTP/Mg2+ binding site [chemical binding]; other site
679897003719	Switch I region; other site
679897003720	G2 box; other site
679897003721	G3 box; other site
679897003722	Switch II region; other site
679897003723	G4 box; other site
679897003724	G5 box; other site
679897003725	PS00294 Prenyl group binding site (CAAX box).
679897003726	HMMPfam hit to PF01926, MMR_HSR1, score 1.1e-35
679897003727	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003728	HMMPfam hit to PF01926, MMR_HSR1, score 1.8e-38
679897003729	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003730	MraW methylase family; Region: Methyltransf_5; cl17771
679897003731	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
679897003732	HMMPfam hit to PF01795, Methyltransf_5, score 1.7e-101
679897003733	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
679897003734	MarR family; Region: MarR_2; pfam12802
679897003735	HMMPfam hit to PF01047, MarR, score 2.5e-10
679897003736	PS01117 Bacterial regulatory proteins, marR family signature.
679897003737	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
679897003738	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
679897003739	HlyD family secretion protein; Region: HlyD_3; pfam13437
679897003740	putative membrane fusion protein; Region: TIGR02828
679897003741	HMMPfam hit to PF00529, HlyD, score 1.9e-09
679897003742	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
679897003743	Signal peptide predicted for HMU07590 by SignalP 2.0 HMM (Signal peptide probability 0.860) with cleavage site probability 0.288 between residues 48 and 49
679897003744	HMMPfam hit to PF00873, ACR_tran, score 5.2e-99
679897003745	12 probable transmembrane helices predicted for HMU07590 by TMHMM2.0 at aa 7-29, 334-356, 363-382, 392-414, 434-456, 471-493, 535-554, 867-889, 891-913, 923-945, 966-988 and 1003-1025
679897003746	phosphoglyceromutase; Provisional; Region: PRK05434
679897003747	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
679897003748	HMMPfam hit to PF01676, Metalloenzyme, score 9.9e-44
679897003749	HMMPfam hit to PF06415, iPGM_N, score 3e-183
679897003750	Signal peptide predicted for HMU07610 by SignalP 2.0 HMM (Signal peptide probability 0.972) with cleavage site probability 0.236 between residues 28 and 29
679897003751	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
679897003752	HMMPfam hit to PF02092, tRNA_synt_2f, score 3.4e-182
679897003753	Outer membrane efflux protein; Region: OEP; pfam02321
679897003754	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
679897003755	Signal peptide predicted for HMU07630 by SignalP 2.0 HMM (Signal peptide probability 0.967) with cleavage site probability 0.327 between residues 29 and 30
679897003756	1 probable transmembrane helix predicted for HMU07630 by TMHMM2.0 at aa 12-29
679897003757	HMMPfam hit to PF02321, OEP, score 0.0014
679897003758	HMMPfam hit to PF02321, OEP, score 0.00071
679897003759	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
679897003760	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
679897003761	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
679897003762	Signal peptide predicted for HMU07650 by SignalP 2.0 HMM (Signal peptide probability 0.808) with cleavage site probability 0.747 between residues 38 and 39
679897003763	HMMPfam hit to PF00873, ACR_tran, score 0
679897003764	12 probable transmembrane helices predicted for HMU07650 by TMHMM2.0 at aa 13-35, 336-353, 358-375, 388-410, 431-453, 468-490, 522-541, 856-875, 882-901, 911-933, 954-973 and 986-1008
679897003765	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897003766	Protein of unknown function (DUF3240); Region: DUF3240; pfam11582
679897003767	UGMP family protein; Validated; Region: PRK09604
679897003768	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
679897003769	HMMPfam hit to PF00814, Peptidase_M22, score 2.2e-52
679897003770	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
679897003771	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
679897003772	HMMPfam hit to PF04371, PAD_porph, score 2.2e-126
679897003773	Acylphosphatase; Region: Acylphosphatase; pfam00708
679897003774	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
679897003775	HypF finger; Region: zf-HYPF; pfam07503
679897003776	HypF finger; Region: zf-HYPF; pfam07503
679897003777	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
679897003778	HMMPfam hit to PF00708, Acylphosphatase, score 2e-10
679897003779	PS00150 Acylphosphatase signature 1.
679897003780	HMMPfam hit to PF07503, zf-HYPF, score 1.9e-07
679897003781	HMMPfam hit to PF07503, zf-HYPF, score 1.6e-12
679897003782	HMMPfam hit to PF01300, Sua5_yciO_yrdC, score 5.4e-50
679897003783	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
679897003784	Sodium:sulfate symporter transmembrane region; Region: Na_sulph_symp; pfam00939
679897003785	transmembrane helices; other site
679897003786	Signal peptide predicted for HMU07700 by SignalP 2.0 HMM (Signal peptide probability 0.806) with cleavage site probability 0.748 between residues 28 and 29
679897003787	HMMPfam hit to PF00939, Na_sulph_symp, score 5.4e-192
679897003788	13 probable transmembrane helices predicted for HMU07700 by TMHMM2.0 at aa 5-22, 32-66, 87-109, 129-148, 183-205, 225-247, 278-295, 299-321, 333-355, 370-387, 394-411, 421-443 and 455-477
679897003789	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
679897003790	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
679897003791	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
679897003792	HMMPfam hit to PF00023, Ank, score 0.23
679897003793	HMMPfam hit to PF00023, Ank, score 0.0062
679897003794	HMMPfam hit to PF00023, Ank, score 6.5e-08
679897003795	HMMPfam hit to PF00023, Ank, score 12
679897003796	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
679897003797	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
679897003798	active site
679897003799	substrate binding site [chemical binding]; other site
679897003800	cosubstrate binding site; other site
679897003801	catalytic site [active]
679897003802	HMMPfam hit to PF00551, Formyl_trans_N, score 6.6e-54
679897003803	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
679897003804	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
679897003805	13 probable transmembrane helices predicted for HMU07730 by TMHMM2.0 at aa 4-26, 33-50, 55-77, 90-109, 114-131, 143-165, 180-202, 223-240, 244-263, 270-287, 302-324, 331-353 and 366-388
679897003806	HMMPfam hit to PF00999, Na_H_Exchanger, score 1.3e-45
679897003807	Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Region: DapD; COG2171
679897003808	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
679897003809	putative trimer interface [polypeptide binding]; other site
679897003810	putative CoA binding site [chemical binding]; other site
679897003811	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
679897003812	Sel1-like repeats; Region: SEL1; smart00671
679897003813	Sel1-like repeats; Region: SEL1; smart00671
679897003814	Signal peptide predicted for HMU07750 by SignalP 2.0 HMM (Signal peptide probability 0.781) with cleavage site probability 0.228 between residues 45 and 46
679897003815	HMMPfam hit to PF08238, Sel1, score 0.015
679897003816	HMMPfam hit to PF08238, Sel1, score 1.3e-05
679897003817	HMMPfam hit to PF08238, Sel1, score 0.32
679897003818	HMMPfam hit to PF08238, Sel1, score 2.3e-09
679897003819	HMMPfam hit to PF08238, Sel1, score 0.00012
679897003820	HMMPfam hit to PF08238, Sel1, score 0.00072
679897003821	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08447
679897003822	ATP cone domain; Region: ATP-cone; pfam03477
679897003823	Class I ribonucleotide reductase; Region: RNR_I; cd01679
679897003824	active site
679897003825	dimer interface [polypeptide binding]; other site
679897003826	catalytic residues [active]
679897003827	effector binding site; other site
679897003828	R2 peptide binding site; other site
679897003829	HMMPfam hit to PF02867, Ribonuc_red_lgC, score 1.6e-128
679897003830	PS00089 Ribonucleotide reductase large subunit signature.
679897003831	HMMPfam hit to PF00317, Ribonuc_red_lgN, score 1.2e-31
679897003832	HMMPfam hit to PF03477, ATP-cone, score 1.4e-16
679897003833	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
679897003834	dimer interface [polypeptide binding]; other site
679897003835	FMN binding site [chemical binding]; other site
679897003836	HMMPfam hit to PF00881, Nitroreductase, score 2.2e-30
679897003837	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
679897003838	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
679897003839	G1 box; other site
679897003840	putative GEF interaction site [polypeptide binding]; other site
679897003841	GTP/Mg2+ binding site [chemical binding]; other site
679897003842	Switch I region; other site
679897003843	G2 box; other site
679897003844	G3 box; other site
679897003845	Switch II region; other site
679897003846	G4 box; other site
679897003847	G5 box; other site
679897003848	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
679897003849	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
679897003850	HMMPfam hit to PF00679, EFG_C, score 4.5e-25
679897003851	PS00216 Sugar transport proteins signature 1.
679897003852	HMMPfam hit to PF03144, GTP_EFTU_D2, score 3.2e-13
679897003853	HMMPfam hit to PF00009, GTP_EFTU, score 3.6e-75
679897003854	PS00301 GTP-binding elongation factors signature.
679897003855	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003856	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK05842
679897003857	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
679897003858	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
679897003859	HMMPfam hit to PF03963, FlgD, score 1.1e-40
679897003860	flagellar hook protein FlgE; Validated; Region: flgE; PRK05841
679897003861	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
679897003862	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
679897003863	HMMPfam hit to PF00460, Flg_bb_rod, score 3.4e-06
679897003864	PS00588 Flagella basal body rod proteins signature.
679897003865	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
679897003866	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
679897003867	nucleotide binding pocket [chemical binding]; other site
679897003868	K-X-D-G motif; other site
679897003869	catalytic site [active]
679897003870	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
679897003871	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
679897003872	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
679897003873	Dimer interface [polypeptide binding]; other site
679897003874	BRCT sequence motif; other site
679897003875	HMMPfam hit to PF01653, DNA_ligase_aden, score 5.7e-149
679897003876	HMMPfam hit to PF03120, DNA_ligase_OB, score 2.7e-43
679897003877	HMMPfam hit to PF03119, DNA_ligase_ZBD, score 2.8e-08
679897003878	HMMPfam hit to PF00533, BRCT, score 9.9e-11
679897003879	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
679897003880	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
679897003881	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
679897003882	active site
679897003883	dimer interface [polypeptide binding]; other site
679897003884	motif 1; other site
679897003885	motif 2; other site
679897003886	motif 3; other site
679897003887	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
679897003888	anticodon binding site; other site
679897003889	HMMPfam hit to PF07973, tRNA_SAD, score 8.4e-22
679897003890	HMMPfam hit to PF00587, tRNA-synt_2b, score 1e-55
679897003891	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
679897003892	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
679897003893	HMMPfam hit to PF03129, HGTP_anticodon, score 6.9e-25
679897003894	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
679897003895	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
679897003896	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
679897003897	HMMPfam hit to PF05198, IF3_N, score 4.4e-46
679897003898	PS00938 Initiation factor 3 signature.
679897003899	HMMPfam hit to PF00707, IF3_C, score 1.7e-35
679897003900	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
679897003901	23S rRNA binding site [nucleotide binding]; other site
679897003902	L21 binding site [polypeptide binding]; other site
679897003903	L13 binding site [polypeptide binding]; other site
679897003904	HMMPfam hit to PF00453, Ribosomal_L20, score 4.1e-51
679897003905	PS00937 Ribosomal protein L20 signature.
679897003906	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
679897003907	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
679897003908	HMMPfam hit to PF02521, HP_OMP_2, score 7.9e-17
679897003909	Signal peptide predicted for HMU07910 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.821 between residues 25 and 26
679897003910	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
679897003911	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
679897003912	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
679897003913	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
679897003914	HMMPfam hit to PF08436, DXP_redisom_C, score 1.6e-49
679897003915	HMMPfam hit to PF02670, DXP_reductoisom, score 1.6e-47
679897003916	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
679897003917	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
679897003918	HMMPfam hit to PF01148, CTP_transf_1, score 4e-59
679897003919	8 probable transmembrane helices predicted for HMU07930 by TMHMM2.0 at aa 13-30, 34-56, 61-81, 101-123, 130-152, 165-187, 192-214 and 234-256
679897003920	PS01315 Phosphatidate cytidylyltransferase signature.
679897003921	PS00017 ATP/GTP-binding site motif A (P-loop).
679897003922	PS00962 Ribosomal protein S2 signature 1.
679897003923	Signal peptide predicted for HMU07930 by SignalP 2.0 HMM (Signal peptide probability 0.775) with cleavage site probability 0.542 between residues 35 and 36
679897003924	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
679897003925	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
679897003926	NAD binding site [chemical binding]; other site
679897003927	HMMPfam hit to PF00389, 2-Hacid_dh, score 5.8e-22
679897003928	HMMPfam hit to PF02826, 2-Hacid_dh_C, score 4.7e-51
679897003929	PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2.
679897003930	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
679897003931	feedback inhibition sensing region; other site
679897003932	homohexameric interface [polypeptide binding]; other site
679897003933	nucleotide binding site [chemical binding]; other site
679897003934	N-acetyl-L-glutamate binding site [chemical binding]; other site
679897003935	HMMPfam hit to PF00696, AA_kinase, score 1.7e-53
679897003936	Peptide methionine sulfoxide reductase; Region: PMSR; cl00366
679897003937	HMMPfam hit to PF01625, PMSR, score 1.6e-77
679897003938	phosphoenolpyruvate synthase; Validated; Region: PRK06464
679897003939	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
679897003940	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
679897003941	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
679897003942	HMMPfam hit to PF02896, PEP-utilizers_C, score 6.3e-68
679897003943	PS00742 PEP-utilizing enzymes signature 2.
679897003944	HMMPfam hit to PF00391, PEP-utilizers, score 3.7e-38
679897003945	PS00370 PEP-utilizing enzymes phosphorylation site signature.
679897003946	HMMPfam hit to PF01326, PPDK_N, score 2.5e-170
679897003947	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
679897003948	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
679897003949	dimerization interface [polypeptide binding]; other site
679897003950	ATP binding site [chemical binding]; other site
679897003951	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
679897003952	dimerization interface [polypeptide binding]; other site
679897003953	ATP binding site [chemical binding]; other site
679897003954	HMMPfam hit to PF00586, AIRS, score 2e-46
679897003955	HMMPfam hit to PF02769, AIRS_C, score 5.4e-47
679897003956	HMMPfam hit to PF00586, AIRS, score 1.1e-25
679897003957	HMMPfam hit to PF02769, AIRS_C, score 7.4e-15
679897003958	Uncharacterized protein conserved in bacteria (DUF2219); Region: DUF2219; pfam09982
679897003959	Signal peptide predicted for HMU07990 by SignalP 2.0 HMM (Signal peptide probability 0.708) with cleavage site probability 0.701 between residues 16 and 17
679897003960	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
679897003961	Signal peptide predicted for HMU08000 by SignalP 2.0 HMM (Signal peptide probability 0.870) with cleavage site probability 0.388 between residues 16 and 17
679897003962	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
679897003963	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
679897003964	catalytic triad [active]
679897003965	HMMPfam hit to PF00578, AhpC-TSA, score 6.6e-42
679897003966	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
679897003967	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
679897003968	Signal peptide predicted for HMU08020 by SignalP 2.0 HMM (Signal peptide probability 0.975) with cleavage site probability 0.348 between residues 29 and 30
679897003969	3 probable transmembrane helices predicted for HMU08020 by TMHMM2.0 at aa 5-27, 64-86 and 124-143
679897003970	HMMPfam hit to PF01019, G_glu_transpept, score 1.2e-267
679897003971	PS00462 Gamma-glutamyltranspeptidase signature.
679897003972	Uncharacterized conserved protein [Function unknown]; Region: COG1556
679897003973	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
679897003974	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
679897003975	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
679897003976	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
679897003977	HMMPfam hit to PF00037, Fer4, score 0.004
679897003978	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897003979	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897003980	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
679897003981	Cysteine-rich domain; Region: CCG; pfam02754
679897003982	Cysteine-rich domain; Region: CCG; pfam02754
679897003983	HMMPfam hit to PF02754, CCG, score 8.5e-19
679897003984	HMMPfam hit to PF02754, CCG, score 3.9e-11
679897003985	Predicted permeases [General function prediction only]; Region: COG0795
679897003986	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
679897003987	HMMPfam hit to PF03739, YjgP_YjgQ, score 1.8e-35
679897003988	6 probable transmembrane helices predicted for HMU08060 by TMHMM2.0 at aa 9-27, 53-75, 96-118, 264-286, 293-315 and 330-347
679897003989	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
679897003990	putative active site [active]
679897003991	catalytic residue [active]
679897003992	HMMPfam hit to PF01195, Pept_tRNA_hydro, score 2.5e-70
679897003993	PS01196 Peptidyl-tRNA hydrolase signature 2.
679897003994	PS01195 Peptidyl-tRNA hydrolase signature 1.
679897003995	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
679897003996	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
679897003997	5S rRNA interface [nucleotide binding]; other site
679897003998	CTC domain interface [polypeptide binding]; other site
679897003999	L16 interface [polypeptide binding]; other site
679897004000	HMMPfam hit to PF01386, Ribosomal_L25p, score 1.8e-35
679897004001	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
679897004002	RNA binding surface [nucleotide binding]; other site
679897004003	HMMPfam hit to PF01479, S4, score 2.8e-09
679897004004	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
679897004005	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
679897004006	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
679897004007	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
679897004008	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
679897004009	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
679897004010	ATP-grasp domain; Region: ATP-grasp_4; cl17255
679897004011	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
679897004012	IMP binding site; other site
679897004013	dimer interface [polypeptide binding]; other site
679897004014	interdomain contacts; other site
679897004015	partial ornithine binding site; other site
679897004016	HMMPfam hit to PF02142, MGS, score 3.1e-31
679897004017	HMMPfam hit to PF02786, CPSase_L_D2, score 7.1e-11
679897004018	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
679897004019	HMMPfam hit to PF02786, CPSase_L_D2, score 1.4e-17
679897004020	PS00866 Carbamoyl-phosphate synthase subdomain signature 1.
679897004021	HMMPfam hit to PF00289, CPSase_L_chain, score 2.1e-22
679897004022	HMMPfam hit to PF02787, CPSase_L_D3, score 4.5e-47
679897004023	HMMPfam hit to PF02786, CPSase_L_D2, score 4e-119
679897004024	PS00867 Carbamoyl-phosphate synthase subdomain signature 2.
679897004025	HMMPfam hit to PF00289, CPSase_L_chain, score 3.1e-48
679897004026	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897004027	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
679897004028	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
679897004029	1 probable transmembrane helix predicted for HMU08140 by TMHMM2.0 at aa 27-49
679897004030	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897004031	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
679897004032	HsdM N-terminal domain; Region: HsdM_N; pfam12161
679897004033	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897004034	S-adenosylmethionine binding site [chemical binding]; other site
679897004035	HMMPfam hit to PF02384, N6_Mtase, score 2.1e-186
679897004036	PS00092 N-6 Adenine-specific DNA methylases signature.
679897004037	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
679897004038	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
679897004039	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
679897004040	HMMPfam hit to PF01420, Methylase_S, score 3.7e-52
679897004041	HMMPfam hit to PF01420, Methylase_S, score 5.4e-30
679897004042	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
679897004043	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
679897004044	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
679897004045	ATP binding site [chemical binding]; other site
679897004046	putative Mg++ binding site [ion binding]; other site
679897004047	HMMPfam hit to PF04313, HSDR_N, score 2.7e-40
679897004048	HMMPfam hit to PF04851, ResIII, score 7.6e-50
679897004049	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
679897004050	HMMPfam hit to PF03616, Glt_symporter, score 1.2e-210
679897004051	11 probable transmembrane helices predicted for HMU08190 by TMHMM2.0 at aa 5-24, 37-59, 96-118, 125-147, 162-184, 215-237, 242-261, 274-296, 301-323, 335-357 and 367-389
679897004052	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
679897004053	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
679897004054	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
679897004055	active site
679897004056	HMMPfam hit to PF01242, PTPS, score 3.5e-05
679897004057	1 probable transmembrane helix predicted for HMU08220 by TMHMM2.0 at aa 7-29
679897004058	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897004059	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
679897004060	dimerization interface [polypeptide binding]; other site
679897004061	putative ATP binding site [chemical binding]; other site
679897004062	HMMPfam hit to PF02769, AIRS_C, score 9.5e-15
679897004063	PS00443 Glutamine amidotransferases class-II active site.
679897004064	selenium metabolism protein YedF; Region: selenium_YedF; TIGR03527
679897004065	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
679897004066	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
679897004067	Peptidase family M20/M25/M40; Region: Peptidase_M20; pfam01546
679897004068	metal binding site [ion binding]; metal-binding site
679897004069	dimer interface [polypeptide binding]; other site
679897004070	HMMPfam hit to PF01546, Peptidase_M20, score 2.7e-43
679897004071	HMMPfam hit to PF07687, M20_dimer, score 4.8e-14
679897004072	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
679897004073	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
679897004074	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
679897004075	HMMPfam hit to PF01134, GIDA, score 1.8e-251
679897004076	PS01281 Glucose inhibited division protein A family signature 2.
679897004077	PS01280 Glucose inhibited division protein A family signature 1.
679897004078	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
679897004079	Autotransporter beta-domain; Region: Autotransporter; cl17461
679897004080	HMMPfam hit to PF03797, Autotransporter, score 0.0003
679897004081	PS00962 Ribosomal protein S2 signature 1.
679897004082	PS00141 Eukaryotic and viral aspartyl proteases active site.
679897004083	HMMPfam hit to PF06715, Gp5_C, score 0.046
679897004084	Signal peptide predicted for HMU08270 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.663 between residues 28 and 29
679897004085	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
679897004086	Part of AAA domain; Region: AAA_19; pfam13245
679897004087	Family description; Region: UvrD_C_2; pfam13538
679897004088	HMMPfam hit to PF00580, UvrD-helicase, score 1.3e-94
679897004089	PS00017 ATP/GTP-binding site motif A (P-loop).
679897004090	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
679897004091	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
679897004092	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
679897004093	HMMPfam hit to PF01420, Methylase_S, score 8e-33
679897004094	HMMPfam hit to PF01420, Methylase_S, score 1.7e-41
679897004095	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
679897004096	substrate binding site [chemical binding]; other site
679897004097	active site
679897004098	HMMPfam hit to PF01208, URO-D, score 1.1e-125
679897004099	PS00215 Mitochondrial energy transfer proteins signature.
679897004100	PS00907 Uroporphyrinogen decarboxylase signature 2.
679897004101	PS00906 Uroporphyrinogen decarboxylase signature 1.
679897004102	Menaquinone biosynthesis; Region: VitK2_biosynth; cl17475
679897004103	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
679897004104	malonic semialdehyde reductase; Provisional; Region: PRK10538
679897004105	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
679897004106	NAD(P) binding site [chemical binding]; other site
679897004107	active site
679897004108	HMMPfam hit to PF00106, adh_short, score 2.5e-21
679897004109	PS00061 Short-chain dehydrogenases/reductases family signature.
679897004110	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
679897004111	FAD binding domain; Region: FAD_binding_4; pfam01565
679897004112	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
679897004113	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
679897004114	HMMPfam hit to PF01565, FAD_binding_4, score 3.2e-33
679897004115	HMMPfam hit to PF02913, FAD-oxidase_C, score 9.4e-46
679897004116	HMMPfam hit to PF00037, Fer4, score 0.00089
679897004117	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897004118	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897004119	selenocysteine synthase; Provisional; Region: PRK04311
679897004120	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
679897004121	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
679897004122	catalytic residue [active]
679897004123	HMMPfam hit to PF03841, SelA, score 1.7e-164
679897004124	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
679897004125	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
679897004126	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
679897004127	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
679897004128	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
679897004129	DNA binding residues [nucleotide binding]
679897004130	HMMPfam hit to PF04545, Sigma70_r4, score 1.6e-19
679897004131	PS00716 Sigma-70 factors family signature 2.
679897004132	HMMPfam hit to PF04539, Sigma70_r3, score 7e-30
679897004133	HMMPfam hit to PF04542, Sigma70_r2, score 8.9e-28
679897004134	PS00715 Sigma-70 factors family signature 1.
679897004135	HMMPfam hit to PF00140, Sigma70_r1_2, score 1.6e-14
679897004136	Predicted amidohydrolase [General function prediction only]; Region: COG0388
679897004137	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
679897004138	active site
679897004139	catalytic triad [active]
679897004140	dimer interface [polypeptide binding]; other site
679897004141	HMMPfam hit to PF00795, CN_hydrolase, score 0.00015
679897004142	PS00430 TonB-dependent receptor proteins signature 1.
679897004143	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
679897004144	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
679897004145	HMMPfam hit to PF00375, SDF, score 1.8e-38
679897004146	11 probable transmembrane helices predicted for HMU08390 by TMHMM2.0 at aa 15-34, 41-63, 83-105, 125-147, 180-202, 235-254, 269-288, 300-322, 337-359, 372-394 and 399-421
679897004147	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
679897004148	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897004149	S-adenosylmethionine binding site [chemical binding]; other site
679897004150	HMMPfam hit to PF01209, Ubie_methyltran, score 8.4e-23
679897004151	argininosuccinate lyase; Provisional; Region: PRK00855
679897004152	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
679897004153	active sites [active]
679897004154	tetramer interface [polypeptide binding]; other site
679897004155	HMMPfam hit to PF00206, Lyase_1, score 3.3e-84
679897004156	PS00163 Fumarate lyases signature.
679897004157	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
679897004158	HMMPfam hit to PF03653, UPF0093, score 1.2e-54
679897004159	4 probable transmembrane helices predicted for HMU08420 by TMHMM2.0 at aa 15-34, 55-77, 87-109 and 122-144
679897004160	Uncharacterized conserved protein [Function unknown]; Region: COG1739
679897004161	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
679897004162	HMMPfam hit to PF01205, UPF0029, score 1.5e-37
679897004163	PS00910 Uncharacterized protein family UPF0029 signature.
679897004164	META domain; Region: META; cl01245
679897004165	HMMPfam hit to PF03724, META, score 5.9e-05
679897004166	Signal peptide predicted for HMU08440 by SignalP 2.0 HMM (Signal peptide probability 0.780) with cleavage site probability 0.308 between residues 28 and 29
679897004167	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897004168	2 probable transmembrane helices predicted for HMU08460 by TMHMM2.0 at aa 5-22 and 26-48
679897004169	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
679897004170	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
679897004171	active site
679897004172	Zn binding site [ion binding]; other site
679897004173	HMMPfam hit to PF01432, Peptidase_M3, score 6.8e-90
679897004174	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
679897004175	HMMPfam hit to PF08439, Peptidase_M3_N, score 1.8e-15
679897004176	PS00030 Eukaryotic  RNA-binding region RNP-1 signature.
679897004177	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
679897004178	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
679897004179	TrkA-N domain; Region: TrkA_N; pfam02254
679897004180	HMMPfam hit to PF02254, TrkA_N, score 1.8e-19
679897004181	10 probable transmembrane helices predicted for HMU08490 by TMHMM2.0 at aa 5-27, 37-59, 71-93, 97-119, 132-154, 164-186, 207-236, 256-278, 280-302 and 363-385
679897004182	HMMPfam hit to PF00999, Na_H_Exchanger, score 1.2e-60
679897004183	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
679897004184	transcription termination factor Rho; Provisional; Region: rho; PRK09376
679897004185	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
679897004186	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
679897004187	RNA binding site [nucleotide binding]; other site
679897004188	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
679897004189	multimer interface [polypeptide binding]; other site
679897004190	Walker A motif; other site
679897004191	ATP binding site [chemical binding]; other site
679897004192	Walker B motif; other site
679897004193	HMMPfam hit to PF07498, Rho_N, score 6.3e-14
679897004194	HMMPfam hit to PF07497, Rho_RNA_bind, score 4.5e-47
679897004195	HMMPfam hit to PF00006, ATP-synt_ab, score 2.2e-75
679897004196	PS00017 ATP/GTP-binding site motif A (P-loop).
679897004197	glutamate racemase; Provisional; Region: PRK00865
679897004198	HMMPfam hit to PF01177, Asp_Glu_race, score 6.1e-64
679897004199	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
679897004200	PS00923 Aspartate and glutamate racemases signature 1.
679897004201	PS00924 Aspartate and glutamate racemases signature 2.
679897004202	Signal peptide predicted for HMU08570 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.921 between residues 55 and 56
679897004203	1 probable transmembrane helix predicted for HMU08600 by TMHMM2.0 at aa 2-19
679897004204	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
679897004205	Autotransporter beta-domain; Region: Autotransporter; pfam03797
679897004206	HMMPfam hit to PF03797, Autotransporter, score 9.6e-32
679897004207	PS00430 TonB-dependent receptor proteins signature 1.
679897004208	Signal peptide predicted for HMU08630 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.291 between residues 60 and 61
679897004209	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
679897004210	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
679897004211	HMMPfam hit to PF03548, LolA, score 5.8e-53
679897004212	PS00430 TonB-dependent receptor proteins signature 1.
679897004213	Signal peptide predicted for HMU08700 by SignalP 2.0 HMM (Signal peptide probability 0.874) with cleavage site probability 0.725 between residues 52 and 53
679897004214	1 probable transmembrane helix predicted for HMU08700 by TMHMM2.0 at aa 21-43
679897004215	PS00430 TonB-dependent receptor proteins signature 1.
679897004216	1 probable transmembrane helix predicted for HMU08780 by TMHMM2.0 at aa 10-32
679897004217	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897004218	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
679897004219	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
679897004220	active site
679897004221	phosphorylation site [posttranslational modification]
679897004222	intermolecular recognition site; other site
679897004223	dimerization interface [polypeptide binding]; other site
679897004224	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897004225	Walker A motif; other site
679897004226	ATP binding site [chemical binding]; other site
679897004227	Walker B motif; other site
679897004228	arginine finger; other site
679897004229	HMMPfam hit to PF02954, HTH_8, score 2.9e-05
679897004230	HMMPfam hit to PF00158, Sigma54_activat, score 9.2e-136
679897004231	PS00676 Sigma-54 interaction domain ATP-binding region B signature.
679897004232	PS00675 Sigma-54 interaction domain ATP-binding region A signature.
679897004233	HMMPfam hit to PF00072, Response_reg, score 3.5e-26
679897004234	Signal peptide predicted for HMU08800 by SignalP 2.0 HMM (Signal peptide probability 0.734) with cleavage site probability 0.330 between residues 34 and 35
679897004235	1 probable transmembrane helix predicted for HMU08800 by TMHMM2.0 at aa 15-32
679897004236	DNA gyrase subunit A; Validated; Region: PRK05560
679897004237	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
679897004238	CAP-like domain; other site
679897004239	active site
679897004240	primary dimer interface [polypeptide binding]; other site
679897004241	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
679897004242	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
679897004243	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
679897004244	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
679897004245	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
679897004246	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
679897004247	HMMPfam hit to PF03989, DNA_gyraseA_C, score 1e-09
679897004248	HMMPfam hit to PF03989, DNA_gyraseA_C, score 4.1e-14
679897004249	HMMPfam hit to PF03989, DNA_gyraseA_C, score 1.1e-12
679897004250	HMMPfam hit to PF03989, DNA_gyraseA_C, score 7.5e-15
679897004251	HMMPfam hit to PF03989, DNA_gyraseA_C, score 6.7e-14
679897004252	HMMPfam hit to PF03989, DNA_gyraseA_C, score 6.6e-12
679897004253	HMMPfam hit to PF00521, DNA_topoisoIV, score 0
679897004254	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
679897004255	2 probable transmembrane helices predicted for HMU08820 by TMHMM2.0 at aa 111-130 and 180-202
679897004256	HMMPfam hit to PF01219, DAGK_prokar, score 2.1e-21
679897004257	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
679897004258	Signal peptide predicted for HMU08830 by SignalP 2.0 HMM (Signal peptide probability 0.965) with cleavage site probability 0.577 between residues 34 and 35
679897004259	1 probable transmembrane helix predicted for HMU08830 by TMHMM2.0 at aa 7-29
679897004260	Cytochrome c552; Region: Cytochrom_C552; pfam02335
679897004261	HMMPfam hit to PF02335, Cytochrom_C552, score 1.7e-12
679897004262	PS00190 Cytochrome c family heme-binding site signature.
679897004263	PS00190 Cytochrome c family heme-binding site signature.
679897004264	PS00190 Cytochrome c family heme-binding site signature.
679897004265	PS00190 Cytochrome c family heme-binding site signature.
679897004266	PS00190 Cytochrome c family heme-binding site signature.
679897004267	Signal peptide predicted for HMU08840 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.317 between residues 31 and 32
679897004268	1 probable transmembrane helix predicted for HMU08840 by TMHMM2.0 at aa 7-29
679897004269	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
679897004270	HMMPfam hit to PF02492, cobW, score 5.5e-54
679897004271	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypC; COG0298
679897004272	HMMPfam hit to PF01455, HupF_HypC, score 2.3e-29
679897004273	PS01097 Hydrogenases expression/synthesis hupF/hypC family signature.
679897004274	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
679897004275	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
679897004276	HMMPfam hit to PF01924, HypD, score 1.9e-219
679897004277	DNA primase; Validated; Region: dnaG; PRK05667
679897004278	CHC2 zinc finger; Region: zf-CHC2; pfam01807
679897004279	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
679897004280	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
679897004281	active site
679897004282	metal binding site [ion binding]; metal-binding site
679897004283	interdomain interaction site; other site
679897004284	HMMPfam hit to PF01807, zf-CHC2, score 1.3e-55
679897004285	HMMPfam hit to PF08275, Toprim_N, score 1e-42
679897004286	HMMPfam hit to PF01751, Toprim, score 1.2e-13
679897004287	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
679897004288	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
679897004289	Ligand Binding Site [chemical binding]; other site
679897004290	PS00190 Cytochrome c family heme-binding site signature.
679897004291	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
679897004292	Sel1-like repeats; Region: SEL1; smart00671
679897004293	Sel1 repeat; Region: Sel1; cl02723
679897004294	Sel1-like repeats; Region: SEL1; smart00671
679897004295	Signal peptide predicted for HMU08910 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.679 between residues 23 and 24
679897004296	HMMPfam hit to PF08238, Sel1, score 9.9e-06
679897004297	HMMPfam hit to PF08238, Sel1, score 4.9e-06
679897004298	HMMPfam hit to PF08238, Sel1, score 0.00073
679897004299	HMMPfam hit to PF08238, Sel1, score 2e-08
679897004300	HMMPfam hit to PF08238, Sel1, score 0.00067
679897004301	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
679897004302	dimer interface [polypeptide binding]; other site
679897004303	active site
679897004304	HMMPfam hit to PF01380, SIS, score 8e-08
679897004305	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
679897004306	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
679897004307	putative ribose interaction site [chemical binding]; other site
679897004308	putative ADP binding site [chemical binding]; other site
679897004309	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
679897004310	active site
679897004311	HIGH motif; other site
679897004312	nucleotide binding site [chemical binding]; other site
679897004313	HMMPfam hit to PF01467, CTP_transf_2, score 3.5e-25
679897004314	HMMPfam hit to PF00294, PfkB, score 9.9e-39
679897004315	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897004316	PS00584 pfkB family of carbohydrate kinases signature 2.
679897004317	PS00583 pfkB family of carbohydrate kinases signature 1.
679897004318	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
679897004319	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
679897004320	NAD(P) binding site [chemical binding]; other site
679897004321	active site
679897004322	HMMPfam hit to PF01370, Epimerase, score 2e-36
679897004323	histidinol-phosphate phosphatase family domain; Region: Histidinol-ppas; TIGR01656
679897004324	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
679897004325	active site
679897004326	motif I; other site
679897004327	motif II; other site
679897004328	HMMPfam hit to PF00702, Hydrolase, score 9.5e-07
679897004329	Uncharacterized conserved protein [Function unknown]; Region: COG2836
679897004330	6 probable transmembrane helices predicted for HMU08970 by TMHMM2.0 at aa 4-26, 46-68, 78-97, 129-151, 166-188 and 195-213
679897004331	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
679897004332	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
679897004333	HMMPfam hit to PF01634, HisG, score 2.9e-49
679897004334	PS01316 ATP phosphoribosyltransferase signature.
679897004335	pantothenate kinase; Reviewed; Region: PRK13333
679897004336	HMMPfam hit to PF03309, Bvg_acc_factor, score 4.9e-08
679897004337	PQQ-like domain; Region: PQQ_2; pfam13360
679897004338	1 probable transmembrane helix predicted for HMU09020 by TMHMM2.0 at aa 37-54
679897004339	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
679897004340	trimer interface [polypeptide binding]; other site
679897004341	active site
679897004342	HMMPfam hit to PF00692, dUTPase, score 1.3e-35
679897004343	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
679897004344	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
679897004345	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
679897004346	HMMPfam hit to PF01272, GreA_GreB, score 1.7e-36
679897004347	PS00830 Prokaryotic transcription elongation factors signature 2.
679897004348	HMMPfam hit to PF03449, GreA_GreB_N, score 5.1e-37
679897004349	PS00829 Prokaryotic transcription elongation factors signature 1.
679897004350	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
679897004351	Lipid A disaccharide synthetase [Cell envelope biogenesis, outer membrane]; Region: LpxB; COG0763
679897004352	HMMPfam hit to PF02684, LpxB, score 2.6e-98
679897004353	hydrogenase nickel incorporation protein; Provisional; Region: hypA; PRK00564
679897004354	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
679897004355	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
679897004356	HMMPfam hit to PF01155, HypA, score 1.2e-34
679897004357	FOG: WD40 repeat [General function prediction only]; Region: COG2319
679897004358	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
679897004359	structural tetrad; other site
679897004360	HMMPfam hit to PF00400, WD40, score 3.4e-05
679897004361	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
679897004362	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
679897004363	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
679897004364	HMMPfam hit to PF04551, GcpE, score 2.7e-234
679897004365	Signal peptide predicted for HMU09100 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.751 between residues 25 and 26
679897004366	recombination factor protein RarA; Reviewed; Region: PRK13342
679897004367	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897004368	Walker A motif; other site
679897004369	ATP binding site [chemical binding]; other site
679897004370	Walker B motif; other site
679897004371	arginine finger; other site
679897004372	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
679897004373	HMMPfam hit to PF00004, AAA, score 9.1e-18
679897004374	PS00017 ATP/GTP-binding site motif A (P-loop).
679897004375	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
679897004376	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
679897004377	DNA binding residues [nucleotide binding]
679897004378	putative dimer interface [polypeptide binding]; other site
679897004379	HMMPfam hit to PF00376, MerR, score 2.1e-09
679897004380	PS00552 Bacterial regulatory proteins, merR family signature.
679897004381	chaperone protein DnaJ; Provisional; Region: PRK14299
679897004382	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
679897004383	HSP70 interaction site [polypeptide binding]; other site
679897004384	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
679897004385	substrate binding site [polypeptide binding]; other site
679897004386	dimer interface [polypeptide binding]; other site
679897004387	HMMPfam hit to PF01556, DnaJ_C, score 1.2e-17
679897004388	PS00217 Sugar transport proteins signature 2.
679897004389	HMMPfam hit to PF00226, DnaJ, score 4.5e-37
679897004390	PS00636 Nt-dnaJ domain signature.
679897004391	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
679897004392	Signal peptide predicted for HMU09140 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.929 between residues 21 and 22
679897004393	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897004394	PS01159 WW/rsp5/WWP domain signature.
679897004395	Signal peptide predicted for HMU09160 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.909 between residues 21 and 22
679897004396	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
679897004397	EamA-like transporter family; Region: EamA; pfam00892
679897004398	EamA-like transporter family; Region: EamA; pfam00892
679897004399	10 probable transmembrane helices predicted for HMU09170 by TMHMM2.0 at aa 93-115, 125-144, 157-179, 183-205, 212-228, 243-262, 269-287, 302-324, 331-350 and 355-372
679897004400	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
679897004401	HMMPfam hit to PF07719, TPR_2, score 0.004
679897004402	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
679897004403	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
679897004404	active site
679897004405	phosphorylation site [posttranslational modification]
679897004406	intermolecular recognition site; other site
679897004407	dimerization interface [polypeptide binding]; other site
679897004408	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
679897004409	DNA binding site [nucleotide binding]
679897004410	HMMPfam hit to PF00072, Response_reg, score 6.3e-36
679897004411	HMMPfam hit to PF00486, Trans_reg_C, score 1.6e-19
679897004412	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
679897004413	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
679897004414	dimerization interface [polypeptide binding]; other site
679897004415	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
679897004416	dimer interface [polypeptide binding]; other site
679897004417	phosphorylation site [posttranslational modification]
679897004418	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
679897004419	ATP binding site [chemical binding]; other site
679897004420	Mg2+ binding site [ion binding]; other site
679897004421	G-X-G motif; other site
679897004422	Signal peptide predicted for HMU09210 by SignalP 2.0 HMM (Signal peptide probability 0.986) with cleavage site probability 0.381 between residues 36 and 37
679897004423	2 probable transmembrane helices predicted for HMU09210 by TMHMM2.0 at aa 10-29 and 132-154
679897004424	HMMPfam hit to PF00672, HAMP, score 1.9e-09
679897004425	HMMPfam hit to PF00512, HisKA, score 0.00011
679897004426	HMMPfam hit to PF02518, HATPase_c, score 1.1e-07
679897004427	amidophosphoribosyltransferase; Provisional; Region: PRK08525
679897004428	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
679897004429	active site
679897004430	tetramer interface [polypeptide binding]; other site
679897004431	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
679897004432	active site
679897004433	HMMPfam hit to PF00310, GATase_2, score 5.5e-27
679897004434	HMMPfam hit to PF00156, Pribosyltran, score 2e-05
679897004435	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
679897004436	radical SAM protein, TIGR01212 family; Region: TIGR01212
679897004437	PS00228 Tubulin-beta mRNA autoregulation signal.
679897004438	HMMPfam hit to PF04055, Radical_SAM, score 0.0033
679897004439	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
679897004440	dimer interface [polypeptide binding]; other site
679897004441	active site
679897004442	Schiff base residues; other site
679897004443	HMMPfam hit to PF00490, ALAD, score 1.8e-168
679897004444	PS00169 Delta-aminolevulinic acid dehydratase active site.
679897004445	PS00017 ATP/GTP-binding site motif A (P-loop).
679897004446	hypothetical protein; Provisional; Region: PRK12378
679897004447	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
679897004448	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
679897004449	HMMPfam hit to PF07992, Pyr_redox_2, score 3.5e-06
679897004450	HMMPfam hit to PF00070, Pyr_redox, score 2e-10
679897004451	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
679897004452	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
679897004453	putative active site [active]
679897004454	oxyanion strand; other site
679897004455	catalytic triad [active]
679897004456	HMMPfam hit to PF00117, GATase, score 9e-34
679897004457	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
679897004458	EamA-like transporter family; Region: EamA; pfam00892
679897004459	10 probable transmembrane helices predicted for HMU09280 by TMHMM2.0 at aa 3-25, 35-54, 67-89, 94-116, 125-147, 151-168, 175-197, 217-234, 241-263 and 273-292
679897004460	8 probable transmembrane helices predicted for HMU09290 by TMHMM2.0 at aa 40-62, 101-118, 130-161, 176-198, 205-224, 239-258, 265-282 and 322-341
679897004461	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
679897004462	1 probable transmembrane helix predicted for HMU09300 by TMHMM2.0 at aa 5-24
679897004463	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
679897004464	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
679897004465	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897004466	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
679897004467	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897004468	Walker A motif; other site
679897004469	ATP binding site [chemical binding]; other site
679897004470	Walker B motif; other site
679897004471	arginine finger; other site
679897004472	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897004473	Walker A motif; other site
679897004474	ATP binding site [chemical binding]; other site
679897004475	Walker B motif; other site
679897004476	arginine finger; other site
679897004477	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
679897004478	HMMPfam hit to PF07724, AAA_2, score 6.2e-104
679897004479	PS00871 Chaperonins clpA/B signature 2.
679897004480	PS00017 ATP/GTP-binding site motif A (P-loop).
679897004481	HMMPfam hit to PF00004, AAA, score 5.7e-23
679897004482	PS00870 Chaperonins clpA/B signature 1.
679897004483	PS00017 ATP/GTP-binding site motif A (P-loop).
679897004484	HMMPfam hit to PF02861, Clp_N, score 0.1
679897004485	HMMPfam hit to PF02861, Clp_N, score 0.0035
679897004486	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
679897004487	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
679897004488	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
679897004489	protein binding site [polypeptide binding]; other site
679897004490	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
679897004491	Catalytic dyad [active]
679897004492	Signal peptide predicted for HMU09370 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.994 between residues 26 and 27
679897004493	HMMPfam hit to PF00595, PDZ, score 2.2e-15
679897004494	HMMPfam hit to PF03572, Peptidase_S41, score 1.1e-74
679897004495	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
679897004496	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
679897004497	ATP binding site [chemical binding]; other site
679897004498	active site
679897004499	substrate binding site [chemical binding]; other site
679897004500	HMMPfam hit to PF01259, SAICAR_synt, score 2.3e-81
679897004501	PS01057 SAICAR synthetase signature 1.
679897004502	PS01058 SAICAR synthetase signature 2.
679897004503	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; pfam02700
679897004504	HMMPfam hit to PF02700, PurS, score 2.4e-22
679897004505	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
679897004506	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
679897004507	putative active site [active]
679897004508	catalytic triad [active]
679897004509	Signal peptide predicted for HMU09410 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.725 between residues 24 and 25
679897004510	2 probable transmembrane helices predicted for HMU09410 by TMHMM2.0 at aa 285-307 and 314-331
679897004511	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
679897004512	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
679897004513	putative acyl-acceptor binding pocket; other site
679897004514	Signal peptide predicted for HMU09420 by SignalP 2.0 HMM (Signal peptide probability 0.847) with cleavage site probability 0.277 between residues 33 and 34
679897004515	1 probable transmembrane helix predicted for HMU09420 by TMHMM2.0 at aa 7-26
679897004516	HMMPfam hit to PF01553, Acyltransferase, score 2.5e-17
679897004517	potential protein location (hypothetical protein HMU09440 [Helicobacter mustelae 12198]) that overlaps RNA (tRNA-A)
679897004518	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
679897004519	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
679897004520	trmE is a tRNA modification GTPase; Region: trmE; cd04164
679897004521	G1 box; other site
679897004522	GTP/Mg2+ binding site [chemical binding]; other site
679897004523	Switch I region; other site
679897004524	G2 box; other site
679897004525	Switch II region; other site
679897004526	G3 box; other site
679897004527	G4 box; other site
679897004528	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
679897004529	HMMPfam hit to PF01926, MMR_HSR1, score 1.4e-43
679897004530	PS00017 ATP/GTP-binding site motif A (P-loop).
679897004531	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
679897004532	membrane protein insertase; Provisional; Region: PRK01318
679897004533	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
679897004534	KH; found with pubmed blast using H. pylori 26695 HP1450 YidC, and blast of PubMed with the amino acid sequence hits lots of YidC proteins, closest being in H pylori HPAG. Score = 549 bits (1415), Expect = 8e-155 Identities = 290/482 (60%), Positives = 371/482 (76%), Gaps = 10/482 (2%). One of hits is Campylobacter oxaA as assigned. No other homologue on mustalae
679897004535	5 probable transmembrane helices predicted for HMU09470 by TMHMM2.0 at aa 7-29, 345-367, 411-433, 453-472 and 492-514
679897004536	Signal peptide predicted for HMU09470 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.250 between residues 56 and 57
679897004537	Haemolytic domain; Region: Haemolytic; pfam01809
679897004538	Ribonuclease P; Region: Ribonuclease_P; pfam00825
679897004539	HMMPfam hit to PF00825, Ribonuclease_P, score 2.5e-19
679897004540	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
679897004541	HMMPfam hit to PF02472, ExbD, score 7.2e-37
679897004542	Signal peptide predicted for HMU09500 by SignalP 2.0 HMM (Signal peptide probability 0.859) with cleavage site probability 0.337 between residues 35 and 36
679897004543	1 probable transmembrane helix predicted for HMU09500 by TMHMM2.0 at aa 7-29
679897004544	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
679897004545	HMMPfam hit to PF01618, MotA_ExbB, score 6.2e-55
679897004546	3 probable transmembrane helices predicted for HMU09510 by TMHMM2.0 at aa 10-32, 59-81 and 96-118
679897004547	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
679897004548	SmpB-tmRNA interface; other site
679897004549	HMMPfam hit to PF01668, SmpB, score 6.2e-37
679897004550	PS01317 Protein smpB signature.
679897004551	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK04181
679897004552	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
679897004553	HMMPfam hit to PF00288, GHMP_kinases_N, score 1.8e-16
679897004554	carbon storage regulator; Provisional; Region: PRK00568
679897004555	HMMPfam hit to PF02599, CsrA, score 5.5e-26
679897004556	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK04099
679897004557	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
679897004558	active site
679897004559	HMMPfam hit to PF01509, TruB_N, score 3.7e-16
679897004560	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
679897004561	active site
679897004562	dimerization interface [polypeptide binding]; other site
679897004563	HMMPfam hit to PF01725, Ham1p_like, score 5.9e-44
679897004564	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
679897004565	Major Facilitator Superfamily; Region: MFS_1; pfam07690
679897004566	putative substrate translocation pore; other site
679897004567	Heavy-metal-associated domain; Region: HMA; pfam00403
679897004568	Signal peptide predicted for HMU09570 by SignalP 2.0 HMM (Signal peptide probability 0.980) with cleavage site probability 0.420 between residues 29 and 30
679897004569	12 probable transmembrane helices predicted for HMU09570 by TMHMM2.0 at aa 5-26, 41-63, 70-89, 94-116, 129-151, 155-174, 203-225, 240-259, 266-285, 289-307, 327-349 and 359-376
679897004570	HMMPfam hit to PF07690, MFS_1, score 5.8e-59
679897004571	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
679897004572	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
679897004573	Ligand Binding Site [chemical binding]; other site
679897004574	HMMPfam hit to PF01171, ATP_bind_3, score 1.9e-11
679897004575	PS00041 Bacterial regulatory proteins, araC family signature.
679897004576	PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
679897004577	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
679897004578	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
679897004579	active site
679897004580	HIGH motif; other site
679897004581	dimer interface [polypeptide binding]; other site
679897004582	KMSKS motif; other site
679897004583	HMMPfam hit to PF00579, tRNA-synt_1b, score 1.1e-104
679897004584	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
679897004585	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
679897004586	Signal peptide predicted for HMU09610 by SignalP 2.0 HMM (Signal peptide probability 0.875) with cleavage site probability 0.803 between residues 27 and 28
679897004587	HMMPfam hit to PF03840, SecG, score 4.5e-22
679897004588	2 probable transmembrane helices predicted for HMU09610 by TMHMM2.0 at aa 5-22 and 49-71
679897004589	ribosome recycling factor; Reviewed; Region: frr; PRK00083
679897004590	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
679897004591	hinge region; other site
679897004592	HMMPfam hit to PF01765, RRF, score 1.7e-91
679897004593	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
679897004594	active site
679897004595	HMMPfam hit to PF00156, Pribosyltran, score 2e-21
679897004596	PS00103 Purine/pyrimidine phosphoribosyl transferases signature.
679897004597	RDD family; Region: RDD; pfam06271
679897004598	HMMPfam hit to PF06271, RDD, score 1.2e-18
679897004599	3 probable transmembrane helices predicted for HMU09640 by TMHMM2.0 at aa 15-37, 49-68 and 95-117
679897004600	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
679897004601	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
679897004602	6 probable transmembrane helices predicted for HMU09650 by TMHMM2.0 at aa 18-37, 77-99, 103-122, 129-151, 176-198 and 205-222
679897004603	HMMPfam hit to PF00119, ATP-synt_A, score 4.7e-40
679897004604	PS00449 ATP synthase a subunit signature.
679897004605	2 probable transmembrane helices predicted for HMU09660 by TMHMM2.0 at aa 12-34 and 44-66
679897004606	Flavin Reductases; Region: FlaRed; cl00801
679897004607	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
679897004608	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
679897004609	putative active site [active]
679897004610	HMMPfam hit to PF01075, Glyco_transf_9, score 4.4e-33
679897004611	histidyl-tRNA synthetase; Region: hisS; TIGR00442
679897004612	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
679897004613	dimer interface [polypeptide binding]; other site
679897004614	motif 1; other site
679897004615	active site
679897004616	motif 2; other site
679897004617	motif 3; other site
679897004618	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
679897004619	anticodon binding site; other site
679897004620	HMMPfam hit to PF00587, tRNA-synt_2b, score 4.5e-40
679897004621	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
679897004622	HMMPfam hit to PF03129, HGTP_anticodon, score 2.8e-09
679897004623	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cd01483
679897004624	ATP binding site [chemical binding]; other site
679897004625	substrate interface [chemical binding]; other site
679897004626	HMMPfam hit to PF00899, ThiF, score 2.2e-17
679897004627	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
679897004628	Major Facilitator Superfamily; Region: MFS_1; pfam07690
679897004629	putative substrate translocation pore; other site
679897004630	8 probable transmembrane helices predicted for HMU09720 by TMHMM2.0 at aa 13-35, 50-72, 92-114, 147-164, 167-189, 251-273, 285-319 and 363-385
679897004631	HMMPfam hit to PF07690, MFS_1, score 2.3e-08
679897004632	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
679897004633	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
679897004634	HMMPfam hit to PF00534, Glycos_transf_1, score 3.8e-36
679897004635	metal-binding heat shock protein; Provisional; Region: PRK00016
679897004636	HMMPfam hit to PF02130, UPF0054, score 1.6e-31
679897004637	dihydrodipicolinate reductase; Provisional; Region: PRK00048
679897004638	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
679897004639	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
679897004640	HMMPfam hit to PF05173, DapB_C, score 2.2e-58
679897004641	PS01298 Dihydrodipicolinate reductase signature.
679897004642	HMMPfam hit to PF01113, DapB_N, score 2.8e-18
679897004643	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
679897004644	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
679897004645	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
679897004646	HMMPfam hit to PF07992, Pyr_redox_2, score 5e-42
679897004647	HMMPfam hit to PF00070, Pyr_redox, score 1.8e-26
679897004648	PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site.
679897004649	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
679897004650	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
679897004651	catalytic residues [active]
679897004652	HMMPfam hit to PF00085, Thioredoxin, score 1.8e-41
679897004653	PS00194 Thioredoxin family active site.
679897004654	hypothetical protein; Reviewed; Region: PRK12497
679897004655	HMMPfam hit to PF02021, UPF0102, score 1.7e-20
679897004656	homoserine dehydrogenase; Provisional; Region: PRK06349
679897004657	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
679897004658	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
679897004659	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
679897004660	PS00284 Serpins signature.
679897004661	HMMPfam hit to PF01842, ACT, score 1.6e-08
679897004662	HMMPfam hit to PF00742, Homoserine_dh, score 3e-77
679897004663	PS01042 Homoserine dehydrogenase signature.
679897004664	HMMPfam hit to PF03447, NAD_binding_3, score 6.9e-14
679897004665	PS00228 Tubulin-beta mRNA autoregulation signal.
679897004666	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
679897004667	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
679897004668	ABC-ATPase subunit interface; other site
679897004669	HMMPfam hit to PF00528, BPD_transp_1, score 1.9e-47
679897004670	6 probable transmembrane helices predicted for HMU09800 by TMHMM2.0 at aa 9-31, 122-144, 157-179, 212-234, 270-292 and 320-342
679897004671	Signal peptide predicted for HMU09800 by SignalP 2.0 HMM (Signal peptide probability 0.798) with cleavage site probability 0.395 between residues 44 and 45
679897004672	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
679897004673	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
679897004674	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
679897004675	HMMPfam hit to PF00496, SBP_bac_5, score 4.8e-47
679897004676	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
679897004677	HMMPfam hit to PF01975, SurE, score 2.8e-85
679897004678	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
679897004679	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
679897004680	substrate binding pocket [chemical binding]; other site
679897004681	chain length determination region; other site
679897004682	substrate-Mg2+ binding site; other site
679897004683	catalytic residues [active]
679897004684	aspartate-rich region 1; other site
679897004685	active site lid residues [active]
679897004686	aspartate-rich region 2; other site
679897004687	HMMPfam hit to PF00348, polyprenyl_synt, score 3.1e-54
679897004688	PS00444 Polyprenyl synthetases signature 2.
679897004689	PS00723 Polyprenyl synthetases signature 1.
679897004690	PDZ domain; Region: PDZ_2; pfam13180
679897004691	hypothetical protein; Provisional; Region: PRK03762
679897004692	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
679897004693	tetramerization interface [polypeptide binding]; other site
679897004694	active site
679897004695	HMMPfam hit to PF02261, Asp_decarbox, score 3e-60
679897004696	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
679897004697	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
679897004698	putative substrate-binding site; other site
679897004699	nickel binding site [ion binding]; other site
679897004700	HMMPfam hit to PF01750, HycI, score 6.7e-35
679897004701	Ni/Fe-hydrogenase, b-type cytochrome subunit; Region: CytB-hydogenase; TIGR02125
679897004702	HMMPfam hit to PF01292, Ni_hydr_CYTB, score 1.7e-31
679897004703	4 probable transmembrane helices predicted for HMU09890 by TMHMM2.0 at aa 21-43, 58-80, 127-149 and 179-201
679897004704	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
679897004705	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
679897004706	HMMPfam hit to PF00374, NiFeSe_Hases, score 3.8e-276
679897004707	PS00508 Nickel-dependent hydrogenases large subunit signature 2.
679897004708	PS00507 Nickel-dependent hydrogenases large subunit signature 1.
679897004709	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
679897004710	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
679897004711	1 probable transmembrane helix predicted for HMU09910 by TMHMM2.0 at aa 356-375
679897004712	HMMPfam hit to PF01058, Oxidored_q6, score 8.2e-08
679897004713	HMMPfam hit to PF08425, NiFe_dehyd_N, score 9.2e-47
679897004714	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
679897004715	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
679897004716	NAD(P) binding site [chemical binding]; other site
679897004717	homodimer interface [polypeptide binding]; other site
679897004718	substrate binding site [chemical binding]; other site
679897004719	active site
679897004720	HMMPfam hit to PF02719, Polysacc_synt_2, score 1.2e-159
679897004721	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
679897004722	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
679897004723	HMMPfam hit to PF03349, Toluene_X, score 7.1e-10
679897004724	Signal peptide predicted for HMU09930 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.258 between residues 36 and 37
679897004725	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
679897004726	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
679897004727	Cysteine-rich domain; Region: CCG; pfam02754
679897004728	Cysteine-rich domain; Region: CCG; pfam02754
679897004729	HMMPfam hit to PF02754, CCG, score 3e-09
679897004730	HMMPfam hit to PF02754, CCG, score 8.2e-05
679897004731	1 probable transmembrane helix predicted for HMU09940 by TMHMM2.0 at aa 98-115
679897004732	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897004733	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897004734	PS00028 Zinc finger, C2H2 type, domain.
679897004735	HMMPfam hit to PF00037, Fer4, score 0.0059
679897004736	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
679897004737	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
679897004738	FeS/SAM binding site; other site
679897004739	HemN C-terminal domain; Region: HemN_C; pfam06969
679897004740	HMMPfam hit to PF06969, HemN_C, score 9.8e-37
679897004741	HMMPfam hit to PF04055, Radical_SAM, score 2.9e-27
679897004742	Protein of unknown function (DUF2603); Region: DUF2603; pfam10788
679897004743	ornithine carbamoyltransferase; Provisional; Region: PRK00779
679897004744	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
679897004745	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
679897004746	HMMPfam hit to PF00185, OTCace, score 3.6e-66
679897004747	HMMPfam hit to PF02729, OTCace_N, score 7.7e-68
679897004748	PS00097 Aspartate and ornithine carbamoyltransferases signature.
679897004749	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
679897004750	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
679897004751	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
679897004752	ATP binding site [chemical binding]; other site
679897004753	putative Mg++ binding site [ion binding]; other site
679897004754	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
679897004755	nucleotide binding region [chemical binding]; other site
679897004756	ATP-binding site [chemical binding]; other site
679897004757	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
679897004758	HMMPfam hit to PF03461, TRCF, score 2.3e-22
679897004759	HMMPfam hit to PF00271, Helicase_C, score 4.5e-17
679897004760	HMMPfam hit to PF00270, DEAD, score 3.1e-35
679897004761	PS00017 ATP/GTP-binding site motif A (P-loop).
679897004762	HMMPfam hit to PF02559, CarD_TRCF, score 8.1e-36
679897004763	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
679897004764	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
679897004765	Peptidase family M23; Region: Peptidase_M23; pfam01551
679897004766	HMMPfam hit to PF01551, Peptidase_M23, score 1.6e-53
679897004767	Signal peptide predicted for HMU10000 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.369 between residues 51 and 52
679897004768	1 probable transmembrane helix predicted for HMU10000 by TMHMM2.0 at aa 28-50
679897004769	Peptidase family M23; Region: Peptidase_M23; pfam01551
679897004770	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
679897004771	HMMPfam hit to PF01551, Peptidase_M23, score 8.5e-31
679897004772	1 probable transmembrane helix predicted for HMU10010 by TMHMM2.0 at aa 27-49
679897004773	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
679897004774	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
679897004775	HMMPfam hit to PF08245, Mur_ligase_M, score 0.0024
679897004776	PS00017 ATP/GTP-binding site motif A (P-loop).
679897004777	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
679897004778	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
679897004779	metal binding site [ion binding]; metal-binding site
679897004780	active site
679897004781	I-site; other site
679897004782	HMMPfam hit to PF00990, GGDEF, score 1.1e-43
679897004783	Lipopolysaccharide-assembly; Region: LptE; pfam04390
679897004784	Signal peptide predicted for HMU10040 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.750 between residues 26 and 27
679897004785	1 probable transmembrane helix predicted for HMU10040 by TMHMM2.0 at aa 2-24
679897004786	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897004787	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
679897004788	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
679897004789	HIGH motif; other site
679897004790	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
679897004791	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
679897004792	active site
679897004793	KMSKS motif; other site
679897004794	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
679897004795	tRNA binding surface [nucleotide binding]; other site
679897004796	anticodon binding site; other site
679897004797	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897004798	HMMPfam hit to PF01406, tRNA-synt_1e, score 1.9e-05
679897004799	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
679897004800	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
679897004801	Protein export membrane protein; Region: SecD_SecF; pfam02355
679897004802	6 probable transmembrane helices predicted for HMU10060 by TMHMM2.0 at aa 12-34, 137-154, 161-183, 187-209, 240-262 and 272-294
679897004803	HMMPfam hit to PF02355, SecD_SecF, score 1.5e-83
679897004804	HMMPfam hit to PF07549, Sec_GG, score 0.0024
679897004805	Signal peptide predicted for HMU10060 by SignalP 2.0 HMM (Signal peptide probability 0.827) with cleavage site probability 0.422 between residues 46 and 47
679897004806	protein-export membrane protein SecD; Region: secD; TIGR01129
679897004807	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
679897004808	6 probable transmembrane helices predicted for HMU10070 by TMHMM2.0 at aa 9-31, 358-377, 379-401, 405-427, 456-478 and 482-504
679897004809	HMMPfam hit to PF07549, Sec_GG, score 0.0054
679897004810	Signal peptide predicted for HMU10070 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.744 between residues 29 and 30
679897004811	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
679897004812	HMMPfam hit to PF02699, YajC, score 2.5e-35
679897004813	1 probable transmembrane helix predicted for HMU10080 by TMHMM2.0 at aa 4-26
679897004814	pH-dependent sodium/proton antiporter; Provisional; Region: nhaA; PRK14856
679897004815	10 probable transmembrane helices predicted for HMU10090 by TMHMM2.0 at aa 21-40, 101-123, 130-149, 159-181, 188-207, 222-244, 304-323, 333-355, 367-389 and 404-426
679897004816	HMMPfam hit to PF06965, Na_H_antiport_1, score 6.1e-198
679897004817	Signal peptide predicted for HMU10090 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.606 between residues 41 and 42
679897004818	elongation factor P; Validated; Region: PRK00529
679897004819	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
679897004820	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
679897004821	RNA binding site [nucleotide binding]; other site
679897004822	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
679897004823	RNA binding site [nucleotide binding]; other site
679897004824	HMMPfam hit to PF09285, Elong-fact-P_C, score 3.6e-31
679897004825	HMMPfam hit to PF01132, EFP, score 6.7e-32
679897004826	HMMPfam hit to PF08207, EFP_N, score 1e-33
679897004827	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
679897004828	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
679897004829	intersubunit interface [polypeptide binding]; other site
679897004830	active site
679897004831	zinc binding site [ion binding]; other site
679897004832	Na+ binding site [ion binding]; other site
679897004833	HMMPfam hit to PF01116, F_bP_aldolase, score 5.4e-169
679897004834	PS00806 Fructose-bisphosphate aldolase class-II signature 2.
679897004835	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
679897004836	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
679897004837	HMMPfam hit to PF00639, Rotamase, score 7.8e-20
679897004838	Signal peptide predicted for HMU10120 by SignalP 2.0 HMM (Signal peptide probability 0.793) with cleavage site probability 0.619 between residues 22 and 23
679897004839	Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239
679897004840	4 probable transmembrane helices predicted for HMU10130 by TMHMM2.0 at aa 2-24, 29-51, 63-85 and 95-117
679897004841	HMMPfam hit to PF02537, CRCB, score 3.4e-23
679897004842	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897004843	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
679897004844	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
679897004845	active site
679897004846	HMMPfam hit to PF02602, HEM4, score 3.4e-16
679897004847	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
679897004848	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
679897004849	substrate binding site [chemical binding]; other site
679897004850	HMMPfam hit to PF00694, Aconitase_C, score 3.5e-49
679897004851	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
679897004852	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
679897004853	substrate binding site [chemical binding]; other site
679897004854	ligand binding site [chemical binding]; other site
679897004855	HMMPfam hit to PF00330, Aconitase, score 3.3e-229
679897004856	PS01244 Aconitase family signature 2.
679897004857	PS00450 Aconitase family signature 1.
679897004858	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
679897004859	tartrate dehydrogenase; Region: TTC; TIGR02089
679897004860	HMMPfam hit to PF00180, Iso_dh, score 5.2e-160
679897004861	PS00470 Isocitrate and isopropylmalate dehydrogenases signature.
679897004862	2-isopropylmalate synthase; Validated; Region: PRK00915
679897004863	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
679897004864	active site
679897004865	catalytic residues [active]
679897004866	metal binding site [ion binding]; metal-binding site
679897004867	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
679897004868	HMMPfam hit to PF08502, LeuA_dimer, score 5.7e-40
679897004869	HMMPfam hit to PF00682, HMGL-like, score 8.5e-119
679897004870	PS00141 Eukaryotic and viral aspartyl proteases active site.
679897004871	PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1.
679897004872	Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153
679897004873	putative heme binding pocket [chemical binding]; other site
679897004874	Signal peptide predicted for HMU10190 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.612 between residues 26 and 27
679897004875	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897004876	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
679897004877	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
679897004878	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
679897004879	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
679897004880	HMMPfam hit to PF01078, Mg_chelatase, score 2.6e-110
679897004881	PS00017 ATP/GTP-binding site motif A (P-loop).
679897004882	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
679897004883	active site
679897004884	catalytic residues [active]
679897004885	metal binding site [ion binding]; metal-binding site
679897004886	HMMPfam hit to PF01327, Pep_deformylase, score 2.1e-53
679897004887	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
679897004888	I-site; other site
679897004889	active site
679897004890	metal binding site [ion binding]; metal-binding site
679897004891	Clp protease; Region: CLP_protease; pfam00574
679897004892	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
679897004893	oligomer interface [polypeptide binding]; other site
679897004894	active site residues [active]
679897004895	HMMPfam hit to PF00574, CLP_protease, score 2e-127
679897004896	PS00382 Endopeptidase Clp histidine active site.
679897004897	PS00381 Endopeptidase Clp serine active site.
679897004898	trigger factor; Provisional; Region: tig; PRK01490
679897004899	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
679897004900	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
679897004901	HMMPfam hit to PF05698, Trigger_C, score 1.9e-31
679897004902	HMMPfam hit to PF00254, FKBP_C, score 1e-23
679897004903	HMMPfam hit to PF05697, Trigger_N, score 1.9e-31
679897004904	flagellum-specific ATP synthase; Validated; Region: fliI; PRK08472
679897004905	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
679897004906	Walker A motif/ATP binding site; other site
679897004907	Walker B motif; other site
679897004908	HMMPfam hit to PF00006, ATP-synt_ab, score 1.1e-118
679897004909	PS00017 ATP/GTP-binding site motif A (P-loop).
679897004910	PS00152 ATP synthase alpha and beta subunits signature.
679897004911	TLC ATP/ADP transporter; Region: TLC; cl03940
679897004912	TLC ATP/ADP transporter; Region: TLC; cl03940
679897004913	9 probable transmembrane helices predicted for HMU10260 by TMHMM2.0 at aa 19-41, 56-78, 83-105, 115-137, 150-172, 241-260, 281-303, 313-335 and 398-420
679897004914	HMMPfam hit to PF07690, MFS_1, score 1.8e-05
679897004915	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
679897004916	Signal peptide predicted for HMU10260 by SignalP 2.0 HMM (Signal peptide probability 0.691) with cleavage site probability 0.574 between residues 35 and 36
679897004917	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
679897004918	HMMPfam hit to PF02525, Flavodoxin_2, score 3.7e-32
679897004919	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
679897004920	HMMPfam hit to PF01196, Ribosomal_L17, score 1.7e-49
679897004921	PS01167 Ribosomal protein L17 signature.
679897004922	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
679897004923	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
679897004924	alphaNTD homodimer interface [polypeptide binding]; other site
679897004925	alphaNTD - beta interaction site [polypeptide binding]; other site
679897004926	alphaNTD - beta' interaction site [polypeptide binding]; other site
679897004927	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
679897004928	HMMPfam hit to PF03118, RNA_pol_A_CTD, score 2.7e-24
679897004929	PS00017 ATP/GTP-binding site motif A (P-loop).
679897004930	HMMPfam hit to PF01193, RNA_pol_L, score 8.1e-16
679897004931	HMMPfam hit to PF01000, RNA_pol_A_bac, score 1.3e-29
679897004932	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
679897004933	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
679897004934	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
679897004935	RNA binding surface [nucleotide binding]; other site
679897004936	HMMPfam hit to PF01479, S4, score 8.8e-23
679897004937	PS00632 Ribosomal protein S4 signature.
679897004938	HMMPfam hit to PF00163, Ribosomal_S4, score 2e-24
679897004939	30S ribosomal protein S11; Validated; Region: PRK05309
679897004940	HMMPfam hit to PF00411, Ribosomal_S11, score 1.7e-53
679897004941	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
679897004942	30S ribosomal protein S13; Region: bact_S13; TIGR03631
679897004943	HMMPfam hit to PF00416, Ribosomal_S13, score 2.9e-50
679897004944	PS00646 Ribosomal protein S13 signature.
679897004945	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
679897004946	rRNA binding site [nucleotide binding]; other site
679897004947	predicted 30S ribosome binding site; other site
679897004948	HMMPfam hit to PF01176, eIF-1a, score 3e-35
679897004949	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
679897004950	active site
679897004951	HMMPfam hit to PF00557, Peptidase_M24, score 1.3e-54
679897004952	PS00680 Methionine aminopeptidase subfamily 1 signature.
679897004953	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
679897004954	SecY translocase; Region: SecY; pfam00344
679897004955	HMMPfam hit to PF00344, SecY, score 1.9e-119
679897004956	10 probable transmembrane helices predicted for HMU10360 by TMHMM2.0 at aa 13-35, 63-85, 106-126, 141-163, 170-192, 205-227, 257-279, 299-321, 357-376 and 381-398
679897004957	PS00095 C-5 cytosine-specific DNA methylases C-terminal signature.
679897004958	PS00756 Protein secY signature 2.
679897004959	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
679897004960	HMMPfam hit to PF01305, Ribosomal_L15, score 2.2e-46
679897004961	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
679897004962	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
679897004963	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
679897004964	HMMPfam hit to PF03719, Ribosomal_S5_C, score 6.6e-25
679897004965	HMMPfam hit to PF00333, Ribosomal_S5, score 9.8e-35
679897004966	PS00585 Ribosomal protein S5 signature.
679897004967	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
679897004968	23S rRNA interface [nucleotide binding]; other site
679897004969	5S rRNA interface [nucleotide binding]; other site
679897004970	L27 interface [polypeptide binding]; other site
679897004971	L5 interface [polypeptide binding]; other site
679897004972	HMMPfam hit to PF00861, Ribosomal_L18p, score 4.8e-32
679897004973	Signal peptide predicted for HMU10390 by SignalP 2.0 HMM (Signal peptide probability 0.800) with cleavage site probability 0.290 between residues 30 and 31
679897004974	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
679897004975	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
679897004976	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
679897004977	HMMPfam hit to PF00347, Ribosomal_L6, score 2e-29
679897004978	PS00525 Ribosomal protein L6 signature 1.
679897004979	HMMPfam hit to PF00347, Ribosomal_L6, score 7e-06
679897004980	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
679897004981	HMMPfam hit to PF00410, Ribosomal_S8, score 2.5e-43
679897004982	PS00294 Prenyl group binding site (CAAX box).
679897004983	PS00053 Ribosomal protein S8 signature.
679897004984	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
679897004985	HMMPfam hit to PF00253, Ribosomal_S14, score 8.3e-18
679897004986	PS00527 Ribosomal protein S14 signature.
679897004987	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
679897004988	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
679897004989	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
679897004990	HMMPfam hit to PF00673, Ribosomal_L5_C, score 2.6e-44
679897004991	HMMPfam hit to PF00281, Ribosomal_L5, score 3.3e-19
679897004992	PS00358 Ribosomal protein L5 signature.
679897004993	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
679897004994	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
679897004995	RNA binding site [nucleotide binding]; other site
679897004996	HMMPfam hit to PF00467, KOW, score 8.3e-12
679897004997	PS01108 Ribosomal protein L24 signature.
679897004998	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
679897004999	HMMPfam hit to PF00238, Ribosomal_L14, score 7.4e-79
679897005000	PS00049 Ribosomal protein L14 signature.
679897005001	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
679897005002	HMMPfam hit to PF00366, Ribosomal_S17, score 2.4e-25
679897005003	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
679897005004	L23 interface [polypeptide binding]; other site
679897005005	signal recognition particle (SRP54) interaction site; other site
679897005006	trigger factor interaction site; other site
679897005007	23S rRNA interface [nucleotide binding]; other site
679897005008	HMMPfam hit to PF00831, Ribosomal_L29, score 2.6e-09
679897005009	PS00579 Ribosomal protein L29 signature.
679897005010	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
679897005011	23S rRNA interface [nucleotide binding]; other site
679897005012	5S rRNA interface [nucleotide binding]; other site
679897005013	putative antibiotic binding site [chemical binding]; other site
679897005014	L25 interface [polypeptide binding]; other site
679897005015	L27 interface [polypeptide binding]; other site
679897005016	HMMPfam hit to PF00252, Ribosomal_L16, score 5.6e-47
679897005017	PS00586 Ribosomal protein L16 signature 1.
679897005018	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
679897005019	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
679897005020	G-X-X-G motif; other site
679897005021	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
679897005022	HMMPfam hit to PF00189, Ribosomal_S3_C, score 1.3e-50
679897005023	PS00548 Ribosomal protein S3 signature.
679897005024	HMMPfam hit to PF07650, KH_2, score 1.4e-15
679897005025	HMMPfam hit to PF00417, Ribosomal_S3_N, score 7e-14
679897005026	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
679897005027	putative translocon binding site; other site
679897005028	protein-rRNA interface [nucleotide binding]; other site
679897005029	HMMPfam hit to PF00237, Ribosomal_L22, score 1.9e-36
679897005030	PS00464 Ribosomal protein L22 signature.
679897005031	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
679897005032	HMMPfam hit to PF00203, Ribosomal_S19, score 1.4e-44
679897005033	PS00323 Ribosomal protein S19 signature.
679897005034	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
679897005035	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
679897005036	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
679897005037	HMMPfam hit to PF03947, Ribosomal_L2_C, score 5e-85
679897005038	PS00467 Ribosomal protein L2 signature.
679897005039	HMMPfam hit to PF00181, Ribosomal_L2, score 2.5e-42
679897005040	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
679897005041	HMMPfam hit to PF00276, Ribosomal_L23, score 2.4e-06
679897005042	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
679897005043	HMMPfam hit to PF00573, Ribosomal_L4, score 1.8e-63
679897005044	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
679897005045	HMMPfam hit to PF00297, Ribosomal_L3, score 3.1e-23
679897005046	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
679897005047	HMMPfam hit to PF00338, Ribosomal_S10, score 1.5e-49
679897005048	PS00361 Ribosomal protein S10 signature.
679897005049	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
679897005050	AAA domain; Region: AAA_14; pfam13173
679897005051	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005052	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
679897005053	RNA/DNA hybrid binding site [nucleotide binding]; other site
679897005054	active site
679897005055	HMMPfam hit to PF01351, RNase_HII, score 4.1e-39
679897005056	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897005057	DNA polymerase III subunits gamma and tau; Validated; Region: PRK08451
679897005058	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897005059	Walker A motif; other site
679897005060	ATP binding site [chemical binding]; other site
679897005061	DNA polymerase III subunit delta'; Validated; Region: PRK08485
679897005062	Walker B motif; other site
679897005063	arginine finger; other site
679897005064	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
679897005065	HMMPfam hit to PF00004, AAA, score 1.7e-11
679897005066	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005067	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
679897005068	HMMPfam hit to PF02367, UPF0079, score 2.2e-09
679897005069	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005070	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
679897005071	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
679897005072	Walker A/P-loop; other site
679897005073	ATP binding site [chemical binding]; other site
679897005074	Q-loop/lid; other site
679897005075	ABC transporter signature motif; other site
679897005076	Walker B; other site
679897005077	D-loop; other site
679897005078	H-loop/switch region; other site
679897005079	HMMPfam hit to PF00005, ABC_tran, score 1.9e-62
679897005080	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005081	PS00211 ABC transporters family signature.
679897005082	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
679897005083	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
679897005084	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
679897005085	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
679897005086	HMMPfam hit to PF00309, Sigma54_AID, score 1.1e-08
679897005087	HMMPfam hit to PF04963, Sigma54_CBD, score 3e-07
679897005088	HMMPfam hit to PF04552, Sigma54_DBD, score 2.4e-78
679897005089	PS00717 Sigma-54 factors family signature 1.
679897005090	PS00718 Sigma-54 factors family signature 2.
679897005091	YceI-like domain; Region: YceI; cl01001
679897005092	Signal peptide predicted for HMU10630 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.991 between residues 29 and 30
679897005093	4 probable transmembrane helices predicted for HMU10640 by TMHMM2.0 at aa 71-93, 98-120, 149-171 and 181-203
679897005094	2 probable transmembrane helices predicted for HMU10650 by TMHMM2.0 at aa 13-35 and 40-62
679897005095	Signal peptide predicted for HMU10650 by SignalP 2.0 HMM (Signal peptide probability 0.811) with cleavage site probability 0.598 between residues 38 and 39
679897005096	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
679897005097	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
679897005098	inhibitor-cofactor binding pocket; inhibition site
679897005099	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897005100	catalytic residue [active]
679897005101	HMMPfam hit to PF00202, Aminotran_3, score 5.4e-69
679897005102	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
679897005103	5 probable transmembrane helices predicted for HMU10670 by TMHMM2.0 at aa 13-35, 45-67, 74-96, 151-173 and 193-210
679897005104	HMMPfam hit to PF01810, LysE, score 7.4e-20
679897005105	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
679897005106	HMMPfam hit to PF02521, HP_OMP_2, score 3.5e-54
679897005107	Signal peptide predicted for HMU10680 by SignalP 2.0 HMM (Signal peptide probability 0.610) with cleavage site probability 0.171 between residues 29 and 30
679897005108	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
679897005109	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
679897005110	transmembrane helices; other site
679897005111	HMMPfam hit to PF00939, Na_sulph_symp, score 3.1e-29
679897005112	13 probable transmembrane helices predicted for HMU10690 by TMHMM2.0 at aa 7-26, 36-67, 74-96, 111-133, 161-183, 203-225, 249-271, 286-304, 311-328, 343-365, 372-389, 399-421 and 434-453
679897005113	PS01271 Sodium:sulfate symporter family signature.
679897005114	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897005115	Signal peptide predicted for HMU10690 by SignalP 2.0 HMM (Signal peptide probability 0.966) with cleavage site probability 0.915 between residues 40 and 41
679897005116	Uncharacterized protein, 4-oxalocrotonate tautomerase homolog [General function prediction only]; Region: COG1942
679897005117	active site 1 [active]
679897005118	dimer interface [polypeptide binding]; other site
679897005119	hexamer interface [polypeptide binding]; other site
679897005120	active site 2 [active]
679897005121	HMMPfam hit to PF01361, Tautomerase, score 1.8e-25
679897005122	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
679897005123	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
679897005124	HMMPfam hit to PF07690, MFS_1, score 1.2e-16
679897005125	7 probable transmembrane helices predicted for HMU10750 by TMHMM2.0 at aa 15-36, 57-79, 94-113, 126-148, 153-175, 182-204 and 209-231
679897005126	1 probable transmembrane helix predicted for HMU10760 by TMHMM2.0 at aa 52-74
679897005127	Beta-1,4-N-acetylgalactosaminyltransferase (CgtA); Region: CgtA; pfam06306
679897005128	HMMPfam hit to PF06306, CgtA, score 1.8e-73
679897005129	putative acyltransferase; Provisional; Region: PRK05790
679897005130	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
679897005131	dimer interface [polypeptide binding]; other site
679897005132	active site
679897005133	HMMPfam hit to PF00108, Thiolase_N, score 2.8e-137
679897005134	PS00098 Thiolases acyl-enzyme intermediate signature.
679897005135	HMMPfam hit to PF02803, Thiolase_C, score 9.7e-75
679897005136	PS00737 Thiolases signature 2.
679897005137	PS00099 Thiolases active site.
679897005138	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
679897005139	HMMPfam hit to PF01144, CoA_trans, score 3.5e-95
679897005140	PS01273 CoA transferases signature 1.
679897005141	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
679897005142	HMMPfam hit to PF01144, CoA_trans, score 3.3e-61
679897005143	PS01274 CoA transferases signature 2.
679897005144	PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide.
679897005145	HMMPfam hit to PF02667, SCFA_trans, score 0.00041
679897005146	3 probable transmembrane helices predicted for HMU10820 by TMHMM2.0 at aa 28-50, 62-84 and 110-132
679897005147	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897005148	3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK12429
679897005149	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
679897005150	NAD(P) binding site [chemical binding]; other site
679897005151	active site
679897005152	HMMPfam hit to PF00106, adh_short, score 1e-20
679897005153	PS00061 Short-chain dehydrogenases/reductases family signature.
679897005154	Citrate transporter; Region: CitMHS; pfam03600
679897005155	fructuronate transporter; Provisional; Region: PRK10034; cl15264
679897005156	Signal peptide predicted for HMU10840 by SignalP 2.0 HMM (Signal peptide probability 0.965) with cleavage site probability 0.339 between residues 29 and 30
679897005157	HMMPfam hit to PF03600, CitMHS, score 9e-95
679897005158	9 probable transmembrane helices predicted for HMU10840 by TMHMM2.0 at aa 5-27, 47-69, 96-118, 173-195, 227-244, 248-267, 280-302, 322-344 and 404-426
679897005159	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
679897005160	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
679897005161	Ligand binding site; other site
679897005162	metal-binding site
679897005163	HMMPfam hit to PF01501, Glyco_transf_8, score 5e-39
679897005164	Tripartite tricarboxylate transporter TctA family; Region: TctA; cl00772
679897005165	12 probable transmembrane helices predicted for HMU10860 by TMHMM2.0 at aa 13-35, 50-72, 116-138, 142-164, 171-193, 203-225, 260-282, 321-343, 356-378, 388-410, 417-439 and 467-489
679897005166	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897005167	2 probable transmembrane helices predicted for HMU10870 by TMHMM2.0 at aa 28-62 and 69-91
679897005168	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
679897005169	HMMPfam hit to PF03401, Bug, score 3.4e-11
679897005170	Signal peptide predicted for HMU10880 by SignalP 2.0 HMM (Signal peptide probability 0.964) with cleavage site probability 0.471 between residues 29 and 30
679897005171	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
679897005172	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
679897005173	Walker A/P-loop; other site
679897005174	ATP binding site [chemical binding]; other site
679897005175	Q-loop/lid; other site
679897005176	ABC transporter signature motif; other site
679897005177	Walker B; other site
679897005178	D-loop; other site
679897005179	H-loop/switch region; other site
679897005180	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
679897005181	HMMPfam hit to PF08352, oligo_HPY, score 0.00039
679897005182	HMMPfam hit to PF00005, ABC_tran, score 1.8e-63
679897005183	PS00211 ABC transporters family signature.
679897005184	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005185	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
679897005186	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
679897005187	Walker A/P-loop; other site
679897005188	ATP binding site [chemical binding]; other site
679897005189	Q-loop/lid; other site
679897005190	ABC transporter signature motif; other site
679897005191	Walker B; other site
679897005192	D-loop; other site
679897005193	H-loop/switch region; other site
679897005194	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
679897005195	HMMPfam hit to PF08352, oligo_HPY, score 4e-07
679897005196	HMMPfam hit to PF00005, ABC_tran, score 1.1e-55
679897005197	PS00211 ABC transporters family signature.
679897005198	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005199	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
679897005200	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
679897005201	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
679897005202	dimer interface [polypeptide binding]; other site
679897005203	conserved gate region; other site
679897005204	putative PBP binding loops; other site
679897005205	ABC-ATPase subunit interface; other site
679897005206	HMMPfam hit to PF00528, BPD_transp_1, score 7e-54
679897005207	6 probable transmembrane helices predicted for HMU10910 by TMHMM2.0 at aa 16-38, 91-113, 125-142, 146-165, 195-217 and 252-271
679897005208	Signal peptide predicted for HMU10910 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.480 between residues 46 and 47
679897005209	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
679897005210	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
679897005211	dimer interface [polypeptide binding]; other site
679897005212	conserved gate region; other site
679897005213	putative PBP binding loops; other site
679897005214	ABC-ATPase subunit interface; other site
679897005215	HMMPfam hit to PF00528, BPD_transp_1, score 3.1e-52
679897005216	6 probable transmembrane helices predicted for HMU10920 by TMHMM2.0 at aa 9-31, 100-122, 135-157, 197-219, 255-277 and 305-327
679897005217	Signal peptide predicted for HMU10920 by SignalP 2.0 HMM (Signal peptide probability 0.975) with cleavage site probability 0.294 between residues 43 and 44
679897005218	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
679897005219	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
679897005220	peptide binding site [polypeptide binding]; other site
679897005221	HMMPfam hit to PF00496, SBP_bac_5, score 4.1e-92
679897005222	PS00501 Signal peptidases I serine active site.
679897005223	Signal peptide predicted for HMU10930 by SignalP 2.0 HMM (Signal peptide probability 0.955) with cleavage site probability 0.298 between residues 23 and 24
679897005224	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
679897005225	FtsX-like permease family; Region: FtsX; pfam02687
679897005226	HMMPfam hit to PF02687, FtsX, score 3.9e-44
679897005227	4 probable transmembrane helices predicted for HMU10940 by TMHMM2.0 at aa 21-43, 271-293, 317-351 and 366-388
679897005228	Signal peptide predicted for HMU10940 by SignalP 2.0 HMM (Signal peptide probability 0.956) with cleavage site probability 0.457 between residues 46 and 47
679897005229	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
679897005230	DEAD/DEAH box helicase; Region: DEAD; pfam00270
679897005231	ATP binding site [chemical binding]; other site
679897005232	putative Mg++ binding site [ion binding]; other site
679897005233	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
679897005234	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
679897005235	nucleotide binding region [chemical binding]; other site
679897005236	ATP-binding site [chemical binding]; other site
679897005237	SEC-C motif; Region: SEC-C; pfam02810
679897005238	HMMPfam hit to PF02810, SEC-C, score 8.1e-10
679897005239	HMMPfam hit to PF07516, SecA_SW, score 3.9e-77
679897005240	HMMPfam hit to PF00271, Helicase_C, score 0.0033
679897005241	HMMPfam hit to PF07517, SecA_DEAD, score 7.3e-185
679897005242	HMMPfam hit to PF01043, SecA_PP_bind, score 1.7e-67
679897005243	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
679897005244	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
679897005245	tetramer interface [polypeptide binding]; other site
679897005246	heme binding pocket [chemical binding]; other site
679897005247	NADPH binding site [chemical binding]; other site
679897005248	HMMPfam hit to PF00199, Catalase, score 9.5e-260
679897005249	PS00438 Catalase proximal active site signature.
679897005250	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
679897005251	Transglutaminase/protease-like homologues; Region: TGc; smart00460
679897005252	Signal peptide predicted for HMU10970 by SignalP 2.0 HMM (Signal peptide probability 0.960) with cleavage site probability 0.450 between residues 25 and 26
679897005253	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
679897005254	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
679897005255	molybdopterin cofactor binding site; other site
679897005256	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
679897005257	molybdopterin cofactor binding site; other site
679897005258	HMMPfam hit to PF00384, Molybdopterin, score 4.2e-12
679897005259	HMMPfam hit to PF00384, Molybdopterin, score 7.6e-66
679897005260	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005261	HMMPfam hit to PF01568, Molydop_binding, score 8.8e-33
679897005262	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
679897005263	Signal peptide predicted for HMU11010 by SignalP 2.0 HMM (Signal peptide probability 0.918) with cleavage site probability 0.872 between residues 18 and 19
679897005264	PS00190 Cytochrome c family heme-binding site signature.
679897005265	Herpesvirus capsid shell protein VP19C; Region: Herpes_VP19C; cl17367
679897005266	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
679897005267	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897005268	S-adenosylmethionine binding site [chemical binding]; other site
679897005269	HMMPfam hit to PF03602, Cons_hypoth95, score 6.9e-39
679897005270	PS00092 N-6 Adenine-specific DNA methylases signature.
679897005271	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK08455
679897005272	Signal peptide predicted for HMU11040 by SignalP 2.0 HMM (Signal peptide probability 0.659) with cleavage site probability 0.238 between residues 51 and 52
679897005273	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005274	HMMPfam hit to PF03748, FliL, score 4.5e-39
679897005275	1 probable transmembrane helix predicted for HMU11040 by TMHMM2.0 at aa 15-37
679897005276	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
679897005277	HMMPfam hit to PF01648, ACPS, score 1.7e-18
679897005278	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
679897005279	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
679897005280	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
679897005281	catalytic residue [active]
679897005282	HMMPfam hit to PF00266, Aminotran_5, score 1.9e-106
679897005283	PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site.
679897005284	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897005285	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
679897005286	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
679897005287	trimerization site [polypeptide binding]; other site
679897005288	active site
679897005289	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
679897005290	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
679897005291	HMMPfam hit to PF01592, NifU_N, score 6.6e-65
679897005292	HMMPfam hit to PF04324, Fer2_BFD, score 1e-13
679897005293	HMMPfam hit to PF01106, NifU, score 8.6e-27
679897005294	Signal peptide predicted for HMU11080 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.304 between residues 31 and 32
679897005295	HMMPfam hit to PF01856, HP_OMP, score 0.00014
679897005296	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
679897005297	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
679897005298	molybdopterin cofactor binding site; other site
679897005299	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
679897005300	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
679897005301	molybdopterin cofactor binding site; other site
679897005302	Signal peptide predicted for HMU11090 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.695 between residues 31 and 32
679897005303	HMMPfam hit to PF04879, Molybdop_Fe4S4, score 2.5e-23
679897005304	PS00551 Prokaryotic molybdopterin oxidoreductases signature 1.
679897005305	HMMPfam hit to PF00384, Molybdopterin, score 5.2e-90
679897005306	PS00447 DNA polymerase family A signature.
679897005307	HMMPfam hit to PF01568, Molydop_binding, score 1.6e-35
679897005308	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
679897005309	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
679897005310	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
679897005311	Signal peptide predicted for HMU11100 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.857 between residues 33 and 34
679897005312	1 probable transmembrane helix predicted for HMU11100 by TMHMM2.0 at aa 12-31
679897005313	HMMPfam hit to PF00037, Fer4, score 0.00022
679897005314	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897005315	HMMPfam hit to PF00037, Fer4, score 0.0016
679897005316	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
679897005317	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
679897005318	5 probable transmembrane helices predicted for HMU11110 by TMHMM2.0 at aa 10-32, 92-114, 119-141, 162-183 and 193-215
679897005319	HMMPfam hit to PF00037, Fer4, score 0.00036
679897005320	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897005321	HMMPfam hit to PF00037, Fer4, score 0.00077
679897005322	Nitrate reductase cytochrome c-type subunit (NapB); Region: NapB; pfam03892
679897005323	HMMPfam hit to PF03892, NapB, score 7.6e-46
679897005324	Signal peptide predicted for HMU11120 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.605 between residues 19 and 20
679897005325	PS00190 Cytochrome c family heme-binding site signature.
679897005326	PS00190 Cytochrome c family heme-binding site signature.
679897005327	HMMPfam hit to PF00037, Fer4, score 4.8e-05
679897005328	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897005329	Signal peptide predicted for HMU11140 by SignalP 2.0 HMM (Signal peptide probability 0.778) with cleavage site probability 0.637 between residues 18 and 19
679897005330	NapD protein; Region: NapD; cl01163
679897005331	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
679897005332	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
679897005333	Walker A/P-loop; other site
679897005334	ATP binding site [chemical binding]; other site
679897005335	Q-loop/lid; other site
679897005336	ABC transporter signature motif; other site
679897005337	Walker B; other site
679897005338	D-loop; other site
679897005339	H-loop/switch region; other site
679897005340	HMMPfam hit to PF00005, ABC_tran, score 3.5e-48
679897005341	PS00211 ABC transporters family signature.
679897005342	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005343	apolipoprotein N-acyltransferase; Reviewed; Region: PRK12291
679897005344	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
679897005345	active site
679897005346	catalytic triad [active]
679897005347	dimer interface [polypeptide binding]; other site
679897005348	HMMPfam hit to PF00795, CN_hydrolase, score 6.2e-06
679897005349	7 probable transmembrane helices predicted for HMU11170 by TMHMM2.0 at aa 20-39, 49-68, 75-97, 101-123, 128-150, 154-176 and 183-202
679897005350	Signal peptide predicted for HMU11170 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.267 between residues 40 and 41
679897005351	Colicin V production protein; Region: Colicin_V; pfam02674
679897005352	HMMPfam hit to PF02674, Colicin_V, score 2.9e-21
679897005353	4 probable transmembrane helices predicted for HMU11180 by TMHMM2.0 at aa 7-26, 30-52, 65-87 and 102-124
679897005354	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
679897005355	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
679897005356	dimer interface [polypeptide binding]; other site
679897005357	putative anticodon binding site; other site
679897005358	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
679897005359	motif 1; other site
679897005360	active site
679897005361	motif 2; other site
679897005362	motif 3; other site
679897005363	HMMPfam hit to PF01336, tRNA_anti, score 4.1e-15
679897005364	HMMPfam hit to PF00152, tRNA-synt_2, score 1.9e-113
679897005365	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
679897005366	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
679897005367	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
679897005368	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
679897005369	dimer interface [polypeptide binding]; other site
679897005370	active site
679897005371	glycine-pyridoxal phosphate binding site [chemical binding]; other site
679897005372	folate binding site [chemical binding]; other site
679897005373	HMMPfam hit to PF00464, SHMT, score 9.5e-255
679897005374	PS00096 serine hydroxymethyltransferase pyridoxal-phosphate attachment site.
679897005375	Sporulation related domain; Region: SPOR; pfam05036
679897005376	1 probable transmembrane helix predicted for HMU11210 by TMHMM2.0 at aa 21-43
679897005377	HMMPfam hit to PF05036, SPOR, score 0.14
679897005378	hypothetical protein; Provisional; Region: PRK05839
679897005379	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
679897005380	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897005381	homodimer interface [polypeptide binding]; other site
679897005382	catalytic residue [active]
679897005383	HMMPfam hit to PF00155, Aminotran_1_2, score 2.5e-23
679897005384	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
679897005385	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
679897005386	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
679897005387	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
679897005388	Signal peptide predicted for HMU11230 by SignalP 2.0 HMM (Signal peptide probability 0.758) with cleavage site probability 0.593 between residues 30 and 31
679897005389	HMMPfam hit to PF01225, Mur_ligase, score 5.2e-28
679897005390	HMMPfam hit to PF08245, Mur_ligase_M, score 8.2e-07
679897005391	HMMPfam hit to PF02875, Mur_ligase_C, score 8.4e-12
679897005392	Signal peptide predicted for HMU11240 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.871 between residues 26 and 27
679897005393	2 probable transmembrane helices predicted for HMU11240 by TMHMM2.0 at aa 4-21 and 33-52
679897005394	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
679897005395	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
679897005396	Walker A/P-loop; other site
679897005397	ATP binding site [chemical binding]; other site
679897005398	Q-loop/lid; other site
679897005399	ABC transporter signature motif; other site
679897005400	Walker B; other site
679897005401	D-loop; other site
679897005402	H-loop/switch region; other site
679897005403	Smr domain; Region: Smr; pfam01713
679897005404	HMMPfam hit to PF00488, MutS_V, score 1.9e-07
679897005405	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005406	HMMPfam hit to PF01713, Smr, score 3.3e-25
679897005407	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
679897005408	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
679897005409	P-loop; other site
679897005410	ADP binding residues [chemical binding]; other site
679897005411	Switch I; other site
679897005412	Switch II; other site
679897005413	HMMPfam hit to PF01656, CbiA, score 6e-26
679897005414	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005415	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
679897005416	HMMPfam hit to PF03776, MinE, score 1.3e-29
679897005417	DNA protecting protein DprA; Region: dprA; TIGR00732
679897005418	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
679897005419	HMMPfam hit to PF02481, SMF, score 1.9e-55
679897005420	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
679897005421	HMMPfam hit to PF03652, UPF0081, score 6.3e-18
679897005422	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
679897005423	Mg++ binding site [ion binding]; other site
679897005424	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
679897005425	putative catalytic motif [active]
679897005426	substrate binding site [chemical binding]; other site
679897005427	11 probable transmembrane helices predicted for HMU11300 by TMHMM2.0 at aa 4-26, 46-63, 67-85, 98-117, 122-144, 151-170, 175-197, 202-224, 228-250, 273-295 and 305-327
679897005428	HMMPfam hit to PF00953, Glycos_transf_4, score 5e-11
679897005429	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897005430	Signal peptide predicted for HMU11300 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.580 between residues 30 and 31
679897005431	pilus retraction protein PilT; Region: pilT_fam; TIGR01420
679897005432	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
679897005433	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
679897005434	Walker A motif; other site
679897005435	Walker A/P-loop; other site
679897005436	ATP binding site [chemical binding]; other site
679897005437	ATP binding site [chemical binding]; other site
679897005438	Walker B motif; other site
679897005439	HMMPfam hit to PF00437, GSPII_E, score 2.1e-11
679897005440	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005441	Signal peptide predicted for HMU11320 by SignalP 2.0 HMM (Signal peptide probability 0.801) with cleavage site probability 0.526 between residues 29 and 30
679897005442	1 probable transmembrane helix predicted for HMU11320 by TMHMM2.0 at aa 7-29
679897005443	1 probable transmembrane helix predicted for HMU11330 by TMHMM2.0 at aa 7-26
679897005444	Signal peptide predicted for HMU11330 by SignalP 2.0 HMM (Signal peptide probability 0.986) with cleavage site probability 0.303 between residues 24 and 25
679897005445	Signal peptide predicted for HMU11350 by SignalP 2.0 HMM (Signal peptide probability 0.960) with cleavage site probability 0.260 between residues 45 and 46
679897005446	1 probable transmembrane helix predicted for HMU11350 by TMHMM2.0 at aa 5-27
679897005447	1 probable transmembrane helix predicted for HMU11360 by TMHMM2.0 at aa 155-177
679897005448	Family of unknown function (DUF4006); Region: DUF4006; pfam13179
679897005449	Signal peptide predicted for HMU11370 by SignalP 2.0 HMM (Signal peptide probability 0.938) with cleavage site probability 0.271 between residues 36 and 37
679897005450	1 probable transmembrane helix predicted for HMU11370 by TMHMM2.0 at aa 5-27
679897005451	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
679897005452	Cytochrome c; Region: Cytochrom_C; cl11414
679897005453	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
679897005454	HMMPfam hit to PF00034, Cytochrom_C, score 0.0013
679897005455	PS00190 Cytochrome c family heme-binding site signature.
679897005456	PS00190 Cytochrome c family heme-binding site signature.
679897005457	2 probable transmembrane helices predicted for HMU11380 by TMHMM2.0 at aa 10-32 and 57-79
679897005458	cytochrome c oxidase, cbb3-type, CcoQ subunit, epsilon-Proteobacterial; Region: cbb3_Q_epsi; TIGR02736
679897005459	1 probable transmembrane helix predicted for HMU11390 by TMHMM2.0 at aa 10-29
679897005460	cbb3-type cytochrome c oxidase subunit II; Provisional; Region: PRK14487
679897005461	Cbb3-type cytochrome oxidase, cytochrome c subunit [Energy production and conversion]; Region: CcoO; COG2993
679897005462	HMMPfam hit to PF02433, FixO, score 3.6e-120
679897005463	PS00190 Cytochrome c family heme-binding site signature.
679897005464	1 probable transmembrane helix predicted for HMU11400 by TMHMM2.0 at aa 10-29
679897005465	Signal peptide predicted for HMU11400 by SignalP 2.0 HMM (Signal peptide probability 0.666) with cleavage site probability 0.238 between residues 28 and 29
679897005466	cbb3-type cytochrome c oxidase subunit I; Provisional; Region: PRK14488
679897005467	Low-spin heme binding site [chemical binding]; other site
679897005468	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
679897005469	D-pathway; other site
679897005470	Putative water exit pathway; other site
679897005471	Binuclear center (active site) [active]
679897005472	K-pathway; other site
679897005473	Putative proton exit pathway; other site
679897005474	12 probable transmembrane helices predicted for HMU11410 by TMHMM2.0 at aa 20-42, 62-84, 96-118, 133-155, 167-189, 218-240, 247-269, 284-306, 318-340, 355-377, 398-420 and 447-469
679897005475	HMMPfam hit to PF00115, COX1, score 4.6e-42
679897005476	PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature.
679897005477	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
679897005478	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
679897005479	Ligand Binding Site [chemical binding]; other site
679897005480	HMMPfam hit to PF01171, ATP_bind_3, score 3.3e-58
679897005481	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
679897005482	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
679897005483	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
679897005484	FeS/SAM binding site; other site
679897005485	HMMPfam hit to PF04055, Radical_SAM, score 4.7e-20
679897005486	PS01278 Uncharacterized protein family UPF0004 signature.
679897005487	HMMPfam hit to PF00919, UPF0004, score 1.5e-42
679897005488	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236
679897005489	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
679897005490	active site
679897005491	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cl00309
679897005492	HMMPfam hit to PF00156, Pribosyltran, score 0.00098
679897005493	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
679897005494	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
679897005495	N-terminal plug; other site
679897005496	ligand-binding site [chemical binding]; other site
679897005497	HMMPfam hit to PF00593, TonB_dep_Rec, score 1.2e-22
679897005498	HMMPfam hit to PF07715, Plug, score 9.2e-29
679897005499	PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2.
679897005500	Signal peptide predicted for HMU11450 by SignalP 2.0 HMM (Signal peptide probability 0.901) with cleavage site probability 0.420 between residues 24 and 25
679897005501	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
679897005502	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
679897005503	active site
679897005504	HIGH motif; other site
679897005505	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
679897005506	KMSKS motif; other site
679897005507	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
679897005508	tRNA binding surface [nucleotide binding]; other site
679897005509	anticodon binding site; other site
679897005510	HMMPfam hit to PF01406, tRNA-synt_1e, score 1.8e-165
679897005511	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
679897005512	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
679897005513	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
679897005514	HMMPfam hit to PF00905, Transpeptidase, score 3.5e-54
679897005515	HMMPfam hit to PF03717, PBP_dimer, score 1.2e-29
679897005516	Signal peptide predicted for HMU11470 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.512 between residues 30 and 31
679897005517	1 probable transmembrane helix predicted for HMU11470 by TMHMM2.0 at aa 7-26
679897005518	5 probable transmembrane helices predicted for HMU11480 by TMHMM2.0 at aa 20-42, 51-68, 72-89, 101-120 and 130-149
679897005519	Signal peptide predicted for HMU11480 by SignalP 2.0 HMM (Signal peptide probability 0.724) with cleavage site probability 0.526 between residues 42 and 43
679897005520	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
679897005521	Coenzyme A binding pocket [chemical binding]; other site
679897005522	HMMPfam hit to PF00583, Acetyltransf_1, score 1.4e-12
679897005523	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
679897005524	G1 box; other site
679897005525	GTP/Mg2+ binding site [chemical binding]; other site
679897005526	Switch I region; other site
679897005527	G2 box; other site
679897005528	G3 box; other site
679897005529	Switch II region; other site
679897005530	G4 box; other site
679897005531	G5 box; other site
679897005532	HMMPfam hit to PF01926, MMR_HSR1, score 3.7e-20
679897005533	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005534	OstA-like protein; Region: OstA; pfam03968
679897005535	HMMPfam hit to PF03968, OstA, score 1.9e-24
679897005536	Signal peptide predicted for HMU11510 by SignalP 2.0 HMM (Signal peptide probability 0.940) with cleavage site probability 0.217 between residues 22 and 23
679897005537	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897005538	PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site.
679897005539	Signal peptide predicted for HMU11520 by SignalP 2.0 HMM (Signal peptide probability 0.977) with cleavage site probability 0.341 between residues 33 and 34
679897005540	1 probable transmembrane helix predicted for HMU11520 by TMHMM2.0 at aa 7-26
679897005541	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
679897005542	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
679897005543	active site
679897005544	motif I; other site
679897005545	motif II; other site
679897005546	HMMPfam hit to PF08282, Hydrolase_3, score 1e-11
679897005547	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
679897005548	putative active site pocket [active]
679897005549	4-fold oligomerization interface [polypeptide binding]; other site
679897005550	metal binding residues [ion binding]; metal-binding site
679897005551	3-fold/trimer interface [polypeptide binding]; other site
679897005552	HMMPfam hit to PF00475, IGPD, score 6.6e-56
679897005553	PS00955 Imidazoleglycerol-phosphate dehydratase signature 2.
679897005554	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
679897005555	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
679897005556	Sporulation related domain; Region: SPOR; cl10051
679897005557	HMMPfam hit to PF05036, SPOR, score 3.4e-06
679897005558	HMMPfam hit to PF03330, DPBB_1, score 3.2e-38
679897005559	Signal peptide predicted for HMU11550 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.520 between residues 30 and 31
679897005560	1 probable transmembrane helix predicted for HMU11550 by TMHMM2.0 at aa 5-24
679897005561	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897005562	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
679897005563	N-acetyl-D-glucosamine binding site [chemical binding]; other site
679897005564	catalytic residue [active]
679897005565	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
679897005566	HMMPfam hit to PF01476, LysM, score 1.6e-13
679897005567	HMMPfam hit to PF01464, SLT, score 1.3e-30
679897005568	Signal peptide predicted for HMU11560 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.897 between residues 20 and 21
679897005569	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
679897005570	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
679897005571	active site
679897005572	HMMPfam hit to PF01026, TatD_DNase, score 7.1e-103
679897005573	PS01090 Uncharacterized protein family UPF0006 signature 2.
679897005574	PS01137 Uncharacterized protein family UPF0006 signature 1.
679897005575	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
679897005576	Lumazine binding domain; Region: Lum_binding; pfam00677
679897005577	Lumazine binding domain; Region: Lum_binding; pfam00677
679897005578	HMMPfam hit to PF00677, Lum_binding, score 6.4e-06
679897005579	HMMPfam hit to PF00677, Lum_binding, score 3.3e-32
679897005580	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005581	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
679897005582	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
679897005583	8 probable transmembrane helices predicted for HMU11600 by TMHMM2.0 at aa 5-27, 37-59, 72-91, 95-114, 135-169, 174-196, 203-225 and 235-253
679897005584	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
679897005585	ATP-NAD kinase; Region: NAD_kinase; pfam01513
679897005586	HMMPfam hit to PF01513, NAD_kinase, score 1.7e-42
679897005587	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
679897005588	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
679897005589	Walker A/P-loop; other site
679897005590	ATP binding site [chemical binding]; other site
679897005591	Q-loop/lid; other site
679897005592	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
679897005593	ABC transporter signature motif; other site
679897005594	Walker B; other site
679897005595	D-loop; other site
679897005596	H-loop/switch region; other site
679897005597	HMMPfam hit to PF02463, SMC_N, score 3.9e-09
679897005598	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005599	Domain of unknown function (DUF814); Region: DUF814; pfam05670
679897005600	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
679897005601	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
679897005602	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
679897005603	catalytic site [active]
679897005604	subunit interface [polypeptide binding]; other site
679897005605	HMMPfam hit to PF00117, GATase, score 2.7e-54
679897005606	PS00442 Glutamine amidotransferases class-I active site.
679897005607	HMMPfam hit to PF00988, CPSase_sm_chain, score 1e-49
679897005608	Protein of unknown function (DUF507); Region: DUF507; pfam04368
679897005609	Transglycosylase; Region: Transgly; pfam00912
679897005610	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
679897005611	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
679897005612	HMMPfam hit to PF00905, Transpeptidase, score 1.2e-36
679897005613	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005614	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
679897005615	HMMPfam hit to PF00912, Transgly, score 2.7e-75
679897005616	Signal peptide predicted for HMU11670 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.475 between residues 30 and 31
679897005617	1 probable transmembrane helix predicted for HMU11670 by TMHMM2.0 at aa 7-29
679897005618	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
679897005619	dimer interface [polypeptide binding]; other site
679897005620	putative CheW interface [polypeptide binding]; other site
679897005621	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
679897005622	HMMPfam hit to PF00015, MCPsignal, score 1.5e-43
679897005623	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
679897005624	metal binding site 2 [ion binding]; metal-binding site
679897005625	putative DNA binding helix; other site
679897005626	metal binding site 1 [ion binding]; metal-binding site
679897005627	dimer interface [polypeptide binding]; other site
679897005628	structural Zn2+ binding site [ion binding]; other site
679897005629	HMMPfam hit to PF01475, FUR, score 1.7e-46
679897005630	pseudaminic acid synthase; Region: PseI; TIGR03586
679897005631	NeuB family; Region: NeuB; pfam03102
679897005632	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
679897005633	NeuB binding interface [polypeptide binding]; other site
679897005634	putative substrate binding site [chemical binding]; other site
679897005635	HMMPfam hit to PF08666, SAF, score 2.8e-07
679897005636	HMMPfam hit to PF03102, NeuB, score 2.3e-96
679897005637	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
679897005638	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
679897005639	HMMPfam hit to PF00583, Acetyltransf_1, score 2.2e-09
679897005640	pseudaminic acid biosynthesis-associated protein PseG; Region: PseG; TIGR03590
679897005641	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
679897005642	ligand binding site; other site
679897005643	tetramer interface; other site
679897005644	HMMPfam hit to PF02348, CTP_transf_3, score 2e-29
679897005645	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
679897005646	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
679897005647	HMMPfam hit to PF02107, FlgH, score 9e-73
679897005648	Yqey-like protein; Region: YqeY; pfam09424
679897005649	HMMPfam hit to PF02637, GatB_Yqey, score 1.4e-27
679897005650	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
679897005651	HMMPfam hit to PF00920, ILVD_EDD, score 0
679897005652	PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1.
679897005653	PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2.
679897005654	acetolactate synthase catalytic subunit; Reviewed; Region: PRK07710
679897005655	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
679897005656	PYR/PP interface [polypeptide binding]; other site
679897005657	dimer interface [polypeptide binding]; other site
679897005658	TPP binding site [chemical binding]; other site
679897005659	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
679897005660	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
679897005661	TPP-binding site [chemical binding]; other site
679897005662	dimer interface [polypeptide binding]; other site
679897005663	HMMPfam hit to PF02776, TPP_enzyme_N, score 6.2e-92
679897005664	HMMPfam hit to PF00205, TPP_enzyme_M, score 8.4e-54
679897005665	HMMPfam hit to PF02775, TPP_enzyme_C, score 7.3e-71
679897005666	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
679897005667	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
679897005668	putative valine binding site [chemical binding]; other site
679897005669	dimer interface [polypeptide binding]; other site
679897005670	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
679897005671	HMMPfam hit to PF01842, ACT, score 1.3e-09
679897005672	ketol-acid reductoisomerase; Provisional; Region: PRK05479
679897005673	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
679897005674	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
679897005675	HMMPfam hit to PF07991, IlvN, score 8.7e-115
679897005676	HMMPfam hit to PF01450, IlvC, score 1.8e-81
679897005677	threonine dehydratase; Validated; Region: PRK08639
679897005678	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
679897005679	tetramer interface [polypeptide binding]; other site
679897005680	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897005681	catalytic residue [active]
679897005682	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
679897005683	HMMPfam hit to PF00291, PALP, score 6.8e-88
679897005684	PS00165 serine/threonine dehydratases pyridoxal-phosphate attachment site.
679897005685	HMMPfam hit to PF00585, Thr_dehydrat_C, score 4.2e-24
679897005686	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
679897005687	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
679897005688	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
679897005689	HMMPfam hit to PF00460, Flg_bb_rod, score 5.2e-06
679897005690	PS00588 Flagella basal body rod proteins signature.
679897005691	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
679897005692	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
679897005693	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005694	HMMPfam hit to PF01715, IPPT, score 7e-65
679897005695	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
679897005696	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
679897005697	purine monophosphate binding site [chemical binding]; other site
679897005698	dimer interface [polypeptide binding]; other site
679897005699	putative catalytic residues [active]
679897005700	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
679897005701	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
679897005702	HMMPfam hit to PF02142, MGS, score 4.8e-54
679897005703	HMMPfam hit to PF01808, AICARFT_IMPCHas, score 1.1e-82
679897005704	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
679897005705	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
679897005706	TPP-binding site; other site
679897005707	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
679897005708	PYR/PP interface [polypeptide binding]; other site
679897005709	dimer interface [polypeptide binding]; other site
679897005710	TPP binding site [chemical binding]; other site
679897005711	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
679897005712	HMMPfam hit to PF02780, Transketolase_C, score 3.4e-18
679897005713	HMMPfam hit to PF02779, Transket_pyr, score 6.2e-56
679897005714	PS00801 Transketolase signature 1.
679897005715	flagellar assembly protein H; Validated; Region: fliH; PRK06669
679897005716	Flagellar assembly protein FliH; Region: FliH; pfam02108
679897005717	HMMPfam hit to PF02108, FliH, score 3.2e-05
679897005718	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
679897005719	FliG C-terminal domain; Region: FliG_C; pfam01706
679897005720	HMMPfam hit to PF01706, FliG_C, score 1.5e-54
679897005721	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
679897005722	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
679897005723	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
679897005724	2 probable transmembrane helices predicted for HMU11870 by TMHMM2.0 at aa 23-45 and 446-468
679897005725	HMMPfam hit to PF08345, YscJ_FliF_C, score 2.3e-73
679897005726	HMMPfam hit to PF01514, YscJ_FliF, score 5.1e-60
679897005727	Signal peptide predicted for HMU11870 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.520 between residues 43 and 44
679897005728	histidinol-phosphate aminotransferase; Validated; Region: PRK02731
679897005729	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
679897005730	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897005731	homodimer interface [polypeptide binding]; other site
679897005732	catalytic residue [active]
679897005733	HMMPfam hit to PF00155, Aminotran_1_2, score 1.1e-39
679897005734	PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site.
679897005735	histidinol-phosphatase; Provisional; Region: PRK07328
679897005736	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
679897005737	active site
679897005738	dimer interface [polypeptide binding]; other site
679897005739	HMMPfam hit to PF02811, PHP, score 8.1e-28
679897005740	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
679897005741	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
679897005742	nicotinate (nicotinamide) nucleotide adenylyltransferase; Region: TIGR00482
679897005743	active site
679897005744	(T/H)XGH motif; other site
679897005745	HMMPfam hit to PF01467, CTP_transf_2, score 2e-34
679897005746	nickel responsive regulator; Provisional; Region: PRK00630
679897005747	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
679897005748	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
679897005749	HMMPfam hit to PF08753, NikR_C, score 1.8e-33
679897005750	HMMPfam hit to PF01402, RHH_1, score 8.1e-08
679897005751	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
679897005752	3 probable transmembrane helices predicted for HMU11930 by TMHMM2.0 at aa 48-70, 169-188 and 201-218
679897005753	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
679897005754	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
679897005755	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cd00741
679897005756	nucleophilic elbow; other site
679897005757	catalytic triad; other site
679897005758	HMMPfam hit to PF00561, Abhydrolase_1, score 2.4e-11
679897005759	PS00225 Crystallins beta and gamma 'Greek key' motif signature.
679897005760	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
679897005761	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
679897005762	active site
679897005763	HMMPfam hit to PF01569, PAP2, score 8.2e-22
679897005764	4 probable transmembrane helices predicted for HMU11960 by TMHMM2.0 at aa 7-24, 58-80, 123-145 and 149-168
679897005765	Signal peptide predicted for HMU11960 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.845 between residues 25 and 26
679897005766	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
679897005767	HMMPfam hit to PF01165, Ribosomal_S21, score 1.3e-26
679897005768	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
679897005769	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
679897005770	NAD(P) binding site [chemical binding]; other site
679897005771	active site
679897005772	HMMPfam hit to PF00106, adh_short, score 5.2e-31
679897005773	PS00061 Short-chain dehydrogenases/reductases family signature.
679897005774	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
679897005775	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
679897005776	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
679897005777	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
679897005778	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
679897005779	HMMPfam hit to PF07669, Eco57I, score 0.0014
679897005780	PS00092 N-6 Adenine-specific DNA methylases signature.
679897005781	Uncharacterized conserved protein [Function unknown]; Region: COG4933
679897005782	Fic/DOC family; Region: Fic; cl00960
679897005783	HMMPfam hit to PF02661, Fic, score 4.7e-29
679897005784	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09314
679897005785	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
679897005786	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cl00522
679897005787	HMMPfam hit to PF00926, DHBP_synthase, score 3.5e-127
679897005788	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
679897005789	active site
679897005790	HMMPfam hit to PF03414, Glyco_transf_6, score 2.6e-09
679897005791	Alpha-1,2-fucosyltransferase; Region: Fut1_Fut2_like; cd11301
679897005792	Glycosyl transferase family 11; Region: Glyco_transf_11; pfam01531
679897005793	GDP-Fucose binding site [chemical binding]; other site
679897005794	HMMPfam hit to PF01531, Glyco_transf_11, score 3e-08
679897005795	Domain of unknown function DUF302; Region: DUF302; pfam03625
679897005796	Signal peptide predicted for HMU12070 by SignalP 2.0 HMM (Signal peptide probability 0.936) with cleavage site probability 0.751 between residues 20 and 21
679897005797	Protein of unknown function (DUF511); Region: DUF511; pfam04373
679897005798	von Willebrand factor type A domain; Region: VWA_2; pfam13519
679897005799	HMMPfam hit to PF00092, VWA, score 0.0011
679897005800	Protein of unknown function (DUF1561); Region: DUF1561; pfam07598
679897005801	PS00294 Prenyl group binding site (CAAX box).
679897005802	Signal peptide predicted for HMU12100 by SignalP 2.0 HMM (Signal peptide probability 0.938) with cleavage site probability 0.421 between residues 28 and 29
679897005803	1 probable transmembrane helix predicted for HMU12110 by TMHMM2.0 at aa 23-45
679897005804	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897005805	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
679897005806	Walker A motif; other site
679897005807	ATP binding site [chemical binding]; other site
679897005808	Walker B motif; other site
679897005809	arginine finger; other site
679897005810	HMMPfam hit to PF01580, FtsK_SpoIIIE, score 1.6e-22
679897005811	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005812	DNA sulfur modification protein DndD; Region: DNA_S_dndD; TIGR03185
679897005813	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
679897005814	Walker A/P-loop; other site
679897005815	ATP binding site [chemical binding]; other site
679897005816	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005817	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
679897005818	Active Sites [active]
679897005819	HMMPfam hit to PF01171, ATP_bind_3, score 0.0002
679897005820	GMP synthase; Reviewed; Region: guaA; PRK00074
679897005821	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
679897005822	AMP/PPi binding site [chemical binding]; other site
679897005823	candidate oxyanion hole; other site
679897005824	catalytic triad [active]
679897005825	potential glutamine specificity residues [chemical binding]; other site
679897005826	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
679897005827	ATP Binding subdomain [chemical binding]; other site
679897005828	Ligand Binding sites [chemical binding]; other site
679897005829	Dimerization subdomain; other site
679897005830	HMMPfam hit to PF00958, GMP_synt_C, score 2.1e-54
679897005831	HMMPfam hit to PF03054, tRNA_Me_trans, score 5.4e-07
679897005832	HMMPfam hit to PF00117, GATase, score 1.4e-49
679897005833	PS00442 Glutamine amidotransferases class-I active site.
679897005834	LPP20 lipoprotein; Region: LPP20; pfam02169
679897005835	Signal peptide predicted for HMU12180 by SignalP 2.0 HMM (Signal peptide probability 0.988) with cleavage site probability 0.289 between residues 16 and 17
679897005836	Signal peptide predicted for HMU12190 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.497 between residues 29 and 30
679897005837	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897005838	Protein of unknown function (DUF3897); Region: DUF3897; pfam13036
679897005839	1 probable transmembrane helix predicted for HMU12200 by TMHMM2.0 at aa 7-29
679897005840	Signal peptide predicted for HMU12200 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.569 between residues 27 and 28
679897005841	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897005842	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
679897005843	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK05848
679897005844	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
679897005845	dimerization interface [polypeptide binding]; other site
679897005846	active site
679897005847	HMMPfam hit to PF01729, QRPTase_C, score 1.6e-72
679897005848	HMMPfam hit to PF02749, QRPTase_N, score 9.2e-20
679897005849	quinolinate synthetase; Provisional; Region: PRK09375
679897005850	HMMPfam hit to PF02445, NadA, score 1.7e-135
679897005851	phosphatidylserine decarboxylase; Provisional; Region: PRK03934
679897005852	HMMPfam hit to PF02666, PS_Dcarbxylase, score 2.5e-65
679897005853	arginyl-tRNA-protein transferase; Provisional; Region: PRK01305
679897005854	Arginine-tRNA-protein transferase, N terminus; Region: ATE_N; pfam04376
679897005855	Arginine-tRNA-protein transferase, C terminus; Region: ATE_C; pfam04377
679897005856	HMMPfam hit to PF04377, ATE_C, score 4.5e-36
679897005857	Signal peptide predicted for HMU12260 by SignalP 2.0 HMM (Signal peptide probability 0.972) with cleavage site probability 0.569 between residues 29 and 30
679897005858	1 probable transmembrane helix predicted for HMU12260 by TMHMM2.0 at aa 5-27
679897005859	prenyltransferase; Reviewed; Region: ubiA; PRK12874
679897005860	UbiA prenyltransferase family; Region: UbiA; pfam01040
679897005861	8 probable transmembrane helices predicted for HMU12280 by TMHMM2.0 at aa 11-33, 48-70, 91-113, 118-135, 142-164, 168-190, 222-254 and 269-291
679897005862	HMMPfam hit to PF01040, UbiA, score 1.6e-61
679897005863	Protein of unknown function (DUF502); Region: DUF502; cl01107
679897005864	3 probable transmembrane helices predicted for HMU12290 by TMHMM2.0 at aa 13-35, 45-67 and 74-96
679897005865	Signal peptide predicted for HMU12290 by SignalP 2.0 HMM (Signal peptide probability 0.940) with cleavage site probability 0.486 between residues 30 and 31
679897005866	9 probable transmembrane helices predicted for HMU12300 by TMHMM2.0 at aa 20-39, 178-200, 215-234, 241-263, 278-300, 309-331, 341-363, 370-392 and 407-426
679897005867	HMMPfam hit to PF03772, Competence, score 5.7e-30
679897005868	replicative DNA helicase; Provisional; Region: PRK08506
679897005869	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
679897005870	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
679897005871	Walker A motif; other site
679897005872	ATP binding site [chemical binding]; other site
679897005873	Walker B motif; other site
679897005874	DNA binding loops [nucleotide binding]
679897005875	HMMPfam hit to PF03796, DnaB_C, score 2e-109
679897005876	PS00017 ATP/GTP-binding site motif A (P-loop).
679897005877	HMMPfam hit to PF00772, DnaB, score 9.4e-15
679897005878	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
679897005879	HMMPfam hit to PF03631, Ribonuclease_BN, score 1.2e-31
679897005880	6 probable transmembrane helices predicted for HMU12320 by TMHMM2.0 at aa 25-47, 88-110, 131-153, 163-185, 198-220 and 230-252
679897005881	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
679897005882	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
679897005883	active site
679897005884	phosphorylation site [posttranslational modification]
679897005885	dimerization interface [polypeptide binding]; other site
679897005886	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
679897005887	DNA binding site [nucleotide binding]
679897005888	HMMPfam hit to PF00072, Response_reg, score 1.9e-14
679897005889	HMMPfam hit to PF00486, Trans_reg_C, score 1.2e-18
679897005890	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
679897005891	chaperone protein DnaJ; Region: DnaJ_bact; TIGR02349
679897005892	HSP70 interaction site [polypeptide binding]; other site
679897005893	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
679897005894	substrate binding site [polypeptide binding]; other site
679897005895	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
679897005896	Zn binding sites [ion binding]; other site
679897005897	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
679897005898	dimer interface [polypeptide binding]; other site
679897005899	HMMPfam hit to PF01556, DnaJ_C, score 3.9e-42
679897005900	HMMPfam hit to PF00684, DnaJ_CXXCXGXG, score 2e-26
679897005901	PS00637 CXXCXGXG dnaJ domain signature.
679897005902	HMMPfam hit to PF00226, DnaJ, score 2.1e-36
679897005903	PS00636 Nt-dnaJ domain signature.
679897005904	recombination protein RecR; Reviewed; Region: recR; PRK00076
679897005905	RecR protein; Region: RecR; pfam02132
679897005906	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
679897005907	putative active site [active]
679897005908	putative metal-binding site [ion binding]; other site
679897005909	tetramer interface [polypeptide binding]; other site
679897005910	HMMPfam hit to PF02132, RecR, score 4.3e-10
679897005911	PS01300 RecR protein signature.
679897005912	Cytochrome c; Region: Cytochrom_C; cl11414
679897005913	Signal peptide predicted for HMU12360 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.508 between residues 20 and 21
679897005914	HMMPfam hit to PF00034, Cytochrom_C, score 9.9e-07
679897005915	PS00190 Cytochrome c family heme-binding site signature.
679897005916	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
679897005917	alanine racemase; Reviewed; Region: alr; PRK00053
679897005918	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
679897005919	catalytic residue [active]
679897005920	HMMPfam hit to PF01168, Ala_racemase_N, score 4.9e-22
679897005921	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
679897005922	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
679897005923	Permutation of conserved domain; other site
679897005924	active site
679897005925	HMMPfam hit to PF01142, TruD, score 1.4e-97
679897005926	heat shock protein HtpX; Provisional; Region: PRK02870
679897005927	4 probable transmembrane helices predicted for HMU12390 by TMHMM2.0 at aa 17-39, 54-76, 177-199 and 214-233
679897005928	HMMPfam hit to PF01435, Peptidase_M48, score 6.5e-54
679897005929	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
679897005930	GTP cyclohydrolase I; Provisional; Region: PLN03044
679897005931	active site
679897005932	HMMPfam hit to PF01227, GTP_cyclohydroI, score 2.8e-40
679897005933	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
679897005934	HMMPfam hit to PF01098, FTSW_RODA_SPOVE, score 1.9e-85
679897005935	10 probable transmembrane helices predicted for HMU12410 by TMHMM2.0 at aa 7-29, 39-58, 65-87, 102-124, 144-161, 165-184, 186-208, 291-313, 325-347 and 357-379
679897005936	Signal peptide predicted for HMU12410 by SignalP 2.0 HMM (Signal peptide probability 0.939) with cleavage site probability 0.317 between residues 25 and 26
679897005937	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
679897005938	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
679897005939	PS00588 Flagella basal body rod proteins signature.
679897005940	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
679897005941	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
679897005942	HMMPfam hit to PF00460, Flg_bb_rod, score 9.4e-07
679897005943	PS00588 Flagella basal body rod proteins signature.
679897005944	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK03907
679897005945	HMMPfam hit to PF02049, FliE, score 7e-30
679897005946	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
679897005947	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
679897005948	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
679897005949	Signal peptide predicted for HMU12460 by SignalP 2.0 HMM (Signal peptide probability 0.863) with cleavage site probability 0.381 between residues 49 and 50
679897005950	1 probable transmembrane helix predicted for HMU12460 by TMHMM2.0 at aa 12-31
679897005951	HMMPfam hit to PF03717, PBP_dimer, score 1.1e-14
679897005952	HMMPfam hit to PF00905, Transpeptidase, score 5.5e-81
679897005953	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
679897005954	Signal peptide predicted for HMU12470 by SignalP 2.0 HMM (Signal peptide probability 0.727) with cleavage site probability 0.442 between residues 16 and 17
679897005955	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
679897005956	HMMPfam hit to PF04973, NMN_transporter, score 3.1e-30
679897005957	Signal peptide predicted for HMU12480 by SignalP 2.0 HMM (Signal peptide probability 0.986) with cleavage site probability 0.548 between residues 31 and 32
679897005958	8 probable transmembrane helices predicted for HMU12480 by TMHMM2.0 at aa 12-34, 38-55, 60-77, 82-101, 122-144, 148-165, 172-194 and 198-217
679897005959	Thiamine pyrophosphokinase; Region: TPK; cd07995
679897005960	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
679897005961	active site
679897005962	dimerization interface [polypeptide binding]; other site
679897005963	thiamine binding site [chemical binding]; other site
679897005964	HMMPfam hit to PF04263, TPK_catalytic, score 2.3e-31
679897005965	adenylosuccinate lyase; Provisional; Region: PRK08470
679897005966	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
679897005967	tetramer interface [polypeptide binding]; other site
679897005968	active site
679897005969	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
679897005970	HMMPfam hit to PF00206, Lyase_1, score 2.1e-36
679897005971	PS00163 Fumarate lyases signature.
679897005972	duplicated ustream C-term; ; evidence=IEA
679897005973	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
679897005974	HMMPfam hit to PF01084, Ribosomal_S18, score 5.3e-29
679897005975	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
679897005976	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
679897005977	dimer interface [polypeptide binding]; other site
679897005978	ssDNA binding site [nucleotide binding]; other site
679897005979	tetramer (dimer of dimers) interface [polypeptide binding]; other site
679897005980	HMMPfam hit to PF00436, SSB, score 4.5e-31
679897005981	PS00735 Single-strand binding protein family signature 1.
679897005982	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
679897005983	HMMPfam hit to PF01250, Ribosomal_S6, score 1.4e-48
679897005984	PS01048 Ribosomal protein S6 signature.
679897005985	DNA polymerase III subunit delta; Validated; Region: PRK08487
679897005986	HMMPfam hit to PF06144, DNA_pol3_delta, score 0.0037
679897005987	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
679897005988	RNB domain; Region: RNB; pfam00773
679897005989	HMMPfam hit to PF00773, RNB, score 1.1e-106
679897005990	PS01175 Ribonuclease II family signature.
679897005991	PS00589 PTS HPR component serine phosphorylation site signature.
679897005992	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
679897005993	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
679897005994	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
679897005995	shikimate binding site; other site
679897005996	NAD(P) binding site [chemical binding]; other site
679897005997	HMMPfam hit to PF01488, Shikimate_DH, score 5.6e-14
679897005998	HMMPfam hit to PF08501, Shikimate_dh_N, score 7.2e-18
679897005999	1 probable transmembrane helix predicted for HMU12580 by TMHMM2.0 at aa 7-26
679897006000	Signal peptide predicted for HMU12580 by SignalP 2.0 HMM (Signal peptide probability 0.754) with cleavage site probability 0.311 between residues 23 and 24
679897006001	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
679897006002	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
679897006003	dimerization interface [polypeptide binding]; other site
679897006004	putative ATP binding site [chemical binding]; other site
679897006005	HMMPfam hit to PF02769, AIRS_C, score 1.1e-32
679897006006	HMMPfam hit to PF00586, AIRS, score 1.7e-49
679897006007	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
679897006008	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
679897006009	putative NAD(P) binding site [chemical binding]; other site
679897006010	putative substrate binding site [chemical binding]; other site
679897006011	catalytic Zn binding site [ion binding]; other site
679897006012	structural Zn binding site [ion binding]; other site
679897006013	dimer interface [polypeptide binding]; other site
679897006014	HMMPfam hit to PF00107, ADH_zinc_N, score 4.4e-25
679897006015	HMMPfam hit to PF08240, ADH_N, score 3.1e-35
679897006016	PS00059 Zinc-containing alcohol dehydrogenases signature.
679897006017	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
679897006018	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
679897006019	domain interfaces; other site
679897006020	active site
679897006021	HMMPfam hit to PF03900, Porphobil_deamC, score 1.5e-18
679897006022	PS00533 Porphobilinogen deaminase cofactor-binding site.
679897006023	HMMPfam hit to PF01379, Porphobil_deam, score 4.5e-118
679897006024	FxsA cytoplasmic membrane protein; Region: FxsA; pfam04186
679897006025	3 probable transmembrane helices predicted for HMU12620 by TMHMM2.0 at aa 7-22, 26-48 and 78-100
679897006026	prolyl-tRNA synthetase; Provisional; Region: PRK09194
679897006027	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
679897006028	dimer interface [polypeptide binding]; other site
679897006029	motif 1; other site
679897006030	active site
679897006031	motif 2; other site
679897006032	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
679897006033	putative deacylase active site [active]
679897006034	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
679897006035	active site
679897006036	motif 3; other site
679897006037	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
679897006038	anticodon binding site; other site
679897006039	HMMPfam hit to PF03129, HGTP_anticodon, score 3.7e-18
679897006040	HMMPfam hit to PF00587, tRNA-synt_2b, score 1.5e-60
679897006041	PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1.
679897006042	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
679897006043	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
679897006044	tRNA; other site
679897006045	putative tRNA binding site [nucleotide binding]; other site
679897006046	putative NADP binding site [chemical binding]; other site
679897006047	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
679897006048	HMMPfam hit to PF00745, GlutR_dimer, score 2.9e-13
679897006049	HMMPfam hit to PF01488, Shikimate_DH, score 3e-24
679897006050	HMMPfam hit to PF05201, GlutR_N, score 6.8e-49
679897006051	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
679897006052	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
679897006053	substrate binding pocket [chemical binding]; other site
679897006054	chain length determination region; other site
679897006055	substrate-Mg2+ binding site; other site
679897006056	catalytic residues [active]
679897006057	aspartate-rich region 1; other site
679897006058	active site lid residues [active]
679897006059	aspartate-rich region 2; other site
679897006060	HMMPfam hit to PF00348, polyprenyl_synt, score 3e-31
679897006061	PS00444 Polyprenyl synthetases signature 2.
679897006062	PS00723 Polyprenyl synthetases signature 1.
679897006063	Domain of unknown function (DUF2018); Region: DUF2018; pfam09442
679897006064	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
679897006065	histidinol dehydrogenase; Region: hisD; TIGR00069
679897006066	NAD binding site [chemical binding]; other site
679897006067	dimerization interface [polypeptide binding]; other site
679897006068	product binding site; other site
679897006069	substrate binding site [chemical binding]; other site
679897006070	zinc binding site [ion binding]; other site
679897006071	catalytic residues [active]
679897006072	HMMPfam hit to PF00815, Histidinol_dh, score 4.1e-182
679897006073	PS00611 Histidinol dehydrogenase signature.
679897006074	Ferritin-like domain; Region: Ferritin; pfam00210
679897006075	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
679897006076	dimerization interface [polypeptide binding]; other site
679897006077	DPS ferroxidase diiron center [ion binding]; other site
679897006078	ion pore; other site
679897006079	HMMPfam hit to PF00210, Ferritin, score 8.6e-23
679897006080	PS00819 Dps protein family signature 2.
679897006081	PS00818 Dps protein family signature 1.
679897006082	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
679897006083	Signal peptide predicted for HMU12700 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.299 between residues 20 and 21
679897006084	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
679897006085	binding surface
679897006086	Tetratricopeptide repeat; Region: TPR_16; pfam13432
679897006087	TPR motif; other site
679897006088	1 probable transmembrane helix predicted for HMU12710 by TMHMM2.0 at aa 12-31
679897006089	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
679897006090	RNA/DNA hybrid binding site [nucleotide binding]; other site
679897006091	active site
679897006092	HMMPfam hit to PF00075, RnaseH, score 2e-34
679897006093	ribonuclease III; Reviewed; Region: rnc; PRK00102
679897006094	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
679897006095	dimerization interface [polypeptide binding]; other site
679897006096	active site
679897006097	metal binding site [ion binding]; metal-binding site
679897006098	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
679897006099	dsRNA binding site [nucleotide binding]; other site
679897006100	HMMPfam hit to PF00636, Ribonuclease_3, score 1.8e-41
679897006101	PS00517 Ribonuclease III family signature.
679897006102	HMMPfam hit to PF00035, dsrm, score 7.1e-18
679897006103	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
679897006104	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
679897006105	Tetramer interface [polypeptide binding]; other site
679897006106	active site
679897006107	FMN-binding site [chemical binding]; other site
679897006108	HMMPfam hit to PF01264, Chorismate_synt, score 3.2e-164
679897006109	PS00787 Chorismate synthase signature 1.
679897006110	PS00788 Chorismate synthase signature 2.
679897006111	PS00789 Chorismate synthase signature 3.
679897006112	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
679897006113	flagellar motor switch protein FliY; Validated; Region: PRK08432
679897006114	flagellar motor switch protein FliN; Region: fliN; TIGR02480
679897006115	HMMPfam hit to PF01052, SpoA, score 3.8e-26
679897006116	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
679897006117	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
679897006118	HMMPfam hit to PF01052, SpoA, score 3.2e-12
679897006119	HMMPfam hit to PF02154, FliM, score 1e-112
679897006120	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
679897006121	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
679897006122	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
679897006123	DNA binding residues [nucleotide binding]
679897006124	HMMPfam hit to PF04545, Sigma70_r4, score 1.3e-16
679897006125	HMMPfam hit to PF04542, Sigma70_r2, score 7.9e-13
679897006126	2 probable transmembrane helices predicted for HMU12790 by TMHMM2.0 at aa 7-26 and 31-53
679897006127	Signal peptide predicted for HMU12790 by SignalP 2.0 HMM (Signal peptide probability 0.650) with cleavage site probability 0.389 between residues 25 and 26
679897006128	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
679897006129	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
679897006130	P-loop; other site
679897006131	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
679897006132	HMMPfam hit to PF01656, CbiA, score 1.6e-25
679897006133	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006134	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
679897006135	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
679897006136	HMMPfam hit to PF00448, SRP54, score 1.8e-50
679897006137	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006138	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
679897006139	catalytic center binding site [active]
679897006140	ATP binding site [chemical binding]; other site
679897006141	HMMPfam hit to PF01288, HPPK, score 1.5e-37
679897006142	PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature.
679897006143	1 probable transmembrane helix predicted for HMU12820 by TMHMM2.0 at aa 101-123
679897006144	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
679897006145	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
679897006146	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
679897006147	active site
679897006148	HMMPfam hit to PF00557, Peptidase_M24, score 4.3e-42
679897006149	PS00491 Aminopeptidase P and proline dipeptidase signature.
679897006150	Dehydroquinase class II; Region: DHquinase_II; pfam01220
679897006151	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
679897006152	trimer interface [polypeptide binding]; other site
679897006153	active site
679897006154	dimer interface [polypeptide binding]; other site
679897006155	HMMPfam hit to PF01220, DHquinase_II, score 1.9e-77
679897006156	1 probable transmembrane helix predicted for HMU12840 by TMHMM2.0 at aa 113-135
679897006157	PS01029 Dehydroquinase class II signature.
679897006158	acetylornithine aminotransferase; Provisional; Region: PRK02627
679897006159	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
679897006160	inhibitor-cofactor binding pocket; inhibition site
679897006161	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897006162	catalytic residue [active]
679897006163	HMMPfam hit to PF00202, Aminotran_3, score 8.9e-84
679897006164	PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site.
679897006165	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
679897006166	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
679897006167	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
679897006168	HMMPfam hit to PF00081, Sod_Fe_N, score 8.6e-28
679897006169	HMMPfam hit to PF02777, Sod_Fe_C, score 4.1e-54
679897006170	PS00088 Manganese and iron superoxide dismutases signature.
679897006171	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
679897006172	Major Facilitator Superfamily; Region: MFS_1; pfam07690
679897006173	putative substrate translocation pore; other site
679897006174	Signal peptide predicted for HMU12870 by SignalP 2.0 HMM (Signal peptide probability 0.667) with cleavage site probability 0.453 between residues 46 and 47
679897006175	12 probable transmembrane helices predicted for HMU12870 by TMHMM2.0 at aa 25-47, 62-84, 91-113, 117-139, 151-173, 177-199, 220-239, 254-276, 283-305, 310-332, 344-366 and 370-392
679897006176	HMMPfam hit to PF07690, MFS_1, score 6.8e-38
679897006177	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006178	Methyltransferase domain; Region: Methyltransf_31; pfam13847
679897006179	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897006180	S-adenosylmethionine binding site [chemical binding]; other site
679897006181	HMMPfam hit to PF08242, Methyltransf_12, score 2.7e-08
679897006182	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
679897006183	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
679897006184	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897006185	catalytic residue [active]
679897006186	HMMPfam hit to PF00291, PALP, score 2.1e-09
679897006187	PS00165 serine/threonine dehydratases pyridoxal-phosphate attachment site.
679897006188	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
679897006189	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
679897006190	Signal peptide predicted for HMU12900 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.833 between residues 24 and 25
679897006191	1 probable transmembrane helix predicted for HMU12900 by TMHMM2.0 at aa 5-27
679897006192	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
679897006193	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
679897006194	dimer interface [polypeptide binding]; other site
679897006195	conserved gate region; other site
679897006196	putative PBP binding loops; other site
679897006197	ABC-ATPase subunit interface; other site
679897006198	HMMPfam hit to PF00528, BPD_transp_1, score 3.4e-15
679897006199	5 probable transmembrane helices predicted for HMU12910 by TMHMM2.0 at aa 15-37, 49-71, 86-108, 137-159 and 196-218
679897006200	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
679897006201	ABC-type thiamine transport system, ATPase component [Coenzyme metabolism]; Region: ThiQ; COG3840
679897006202	Walker A/P-loop; other site
679897006203	ATP binding site [chemical binding]; other site
679897006204	Q-loop/lid; other site
679897006205	ABC transporter signature motif; other site
679897006206	Walker B; other site
679897006207	D-loop; other site
679897006208	H-loop/switch region; other site
679897006209	HMMPfam hit to PF00005, ABC_tran, score 1e-55
679897006210	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006211	PS00211 ABC transporters family signature.
679897006212	LPP20 lipoprotein; Region: LPP20; cl15824
679897006213	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
679897006214	Signal peptide predicted for HMU12930 by SignalP 2.0 HMM (Signal peptide probability 0.983) with cleavage site probability 0.295 between residues 29 and 30
679897006215	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006216	Signal peptide predicted for HMU12940 by SignalP 2.0 HMM (Signal peptide probability 0.949) with cleavage site probability 0.667 between residues 33 and 34
679897006217	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006218	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
679897006219	Flavoprotein; Region: Flavoprotein; pfam02441
679897006220	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
679897006221	HMMPfam hit to PF02441, Flavoprotein, score 4.4e-36
679897006222	HMMPfam hit to PF04127, DFP, score 1.1e-10
679897006223	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
679897006224	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
679897006225	HMMPfam hit to PF01408, GFO_IDH_MocA, score 4.2e-30
679897006226	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
679897006227	HMMPfam hit to PF00588, SpoU_methylase, score 1.8e-37
679897006228	Signal peptide predicted for HMU12990 by SignalP 2.0 HMM (Signal peptide probability 0.963) with cleavage site probability 0.957 between residues 15 and 16
679897006229	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
679897006230	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
679897006231	6 probable transmembrane helices predicted for HMU13000 by TMHMM2.0 at aa 10-32, 53-75, 90-112, 133-155, 165-187 and 200-222
679897006232	HMMPfam hit to PF02683, DsbD, score 1.9e-68
679897006233	PS00086 Cytochrome P450 cysteine heme-iron ligand signature.
679897006234	PS00287 Cysteine proteases inhibitors signature.
679897006235	urease subunit beta; Provisional; Region: ureB; PRK13985
679897006236	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
679897006237	subunit interactions [polypeptide binding]; other site
679897006238	active site
679897006239	flap region; other site
679897006240	HMMPfam hit to PF01979, Amidohydro_1, score 1.3e-84
679897006241	HMMPfam hit to PF00449, Urease_alpha, score 2.7e-85
679897006242	urease subunit alpha; Provisional; Region: PRK13986
679897006243	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
679897006244	alpha-gamma subunit interface [polypeptide binding]; other site
679897006245	beta-gamma subunit interface [polypeptide binding]; other site
679897006246	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
679897006247	alpha-beta subunit interface [polypeptide binding]; other site
679897006248	HMMPfam hit to PF00699, Urease_beta, score 9.7e-42
679897006249	HMMPfam hit to PF00547, Urease_gamma, score 2.2e-52
679897006250	helicase 45; Provisional; Region: PTZ00424
679897006251	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
679897006252	ATP binding site [chemical binding]; other site
679897006253	Mg++ binding site [ion binding]; other site
679897006254	motif III; other site
679897006255	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
679897006256	nucleotide binding region [chemical binding]; other site
679897006257	ATP-binding site [chemical binding]; other site
679897006258	HMMPfam hit to PF00270, DEAD, score 2.5e-71
679897006259	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006260	HMMPfam hit to PF00271, Helicase_C, score 3.4e-37
679897006261	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
679897006262	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
679897006263	homodimer interface [polypeptide binding]; other site
679897006264	substrate-cofactor binding pocket; other site
679897006265	catalytic residue [active]
679897006266	HMMPfam hit to PF01063, Aminotran_4, score 6e-90
679897006267	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
679897006268	SPFH domain / Band 7 family; Region: Band_7; pfam01145
679897006269	1 probable transmembrane helix predicted for HMU13050 by TMHMM2.0 at aa 45-64
679897006270	HMMPfam hit to PF01145, Band_7, score 1.2e-45
679897006271	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
679897006272	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
679897006273	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
679897006274	metal binding site [ion binding]; metal-binding site
679897006275	HMMPfam hit to PF01502, PRA-CH, score 4.4e-44
679897006276	HMMPfam hit to PF01503, PRA-PH, score 1.7e-29
679897006277	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
679897006278	2 probable transmembrane helices predicted for HMU13070 by TMHMM2.0 at aa 15-37 and 42-64
679897006279	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
679897006280	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
679897006281	HMMPfam hit to PF01235, Na_Ala_symp, score 2.9e-150
679897006282	9 probable transmembrane helices predicted for HMU13080 by TMHMM2.0 at aa 18-40, 80-102, 146-168, 189-211, 221-243, 307-329, 358-380, 393-410 and 420-442
679897006283	PS00873 Sodium:alanine symporter family signature.
679897006284	Protein of unknown function (DUF493); Region: DUF493; pfam04359
679897006285	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
679897006286	HMMPfam hit to PF03061, 4HBT, score 6.9e-19
679897006287	PS01328 4-hydroxybenzoyl-CoA thioesterase family active site.
679897006288	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
679897006289	Na2 binding site [ion binding]; other site
679897006290	putative substrate binding site 1 [chemical binding]; other site
679897006291	Na binding site 1 [ion binding]; other site
679897006292	putative substrate binding site 2 [chemical binding]; other site
679897006293	HMMPfam hit to PF00209, SNF, score 2.4e-10
679897006294	11 probable transmembrane helices predicted for HMU13110 by TMHMM2.0 at aa 7-24, 34-56, 87-109, 137-159, 166-188, 208-230, 242-264, 293-315, 336-358, 378-400 and 417-439
679897006295	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006296	Uncharacterized conserved protein (DUF2156); Region: DUF2156; cl12090
679897006297	Chorismate mutase type II; Region: CM_2; smart00830
679897006298	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
679897006299	Prephenate dehydratase; Region: PDT; pfam00800
679897006300	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
679897006301	putative L-Phe binding site [chemical binding]; other site
679897006302	HMMPfam hit to PF00800, PDT, score 1.2e-44
679897006303	PS00857 Prephenate dehydratase signature 1.
679897006304	HMMPfam hit to PF01817, CM_2, score 3.2e-20
679897006305	diaminopimelate decarboxylase; Region: lysA; TIGR01048
679897006306	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
679897006307	active site
679897006308	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
679897006309	substrate binding site [chemical binding]; other site
679897006310	catalytic residues [active]
679897006311	dimer interface [polypeptide binding]; other site
679897006312	HMMPfam hit to PF00278, Orn_DAP_Arg_deC, score 7.3e-40
679897006313	HMMPfam hit to PF02784, Orn_Arg_deC_N, score 1.5e-69
679897006314	PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2.
679897006315	Uncharacterized conserved protein [Function unknown]; Region: COG2127
679897006316	HMMPfam hit to PF02617, ClpS, score 1.6e-20
679897006317	ATP-dependent Clp protease ATP-binding subunit clpA; Region: ClpA; TIGR02639
679897006318	Clp amino terminal domain; Region: Clp_N; pfam02861
679897006319	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897006320	Walker A motif; other site
679897006321	ATP binding site [chemical binding]; other site
679897006322	Walker B motif; other site
679897006323	arginine finger; other site
679897006324	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
679897006325	Walker A motif; other site
679897006326	ATP binding site [chemical binding]; other site
679897006327	Walker B motif; other site
679897006328	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
679897006329	HMMPfam hit to PF02861, Clp_N, score 6.6e-09
679897006330	HMMPfam hit to PF00004, AAA, score 8.9e-19
679897006331	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006332	PS00870 Chaperonins clpA/B signature 1.
679897006333	HMMPfam hit to PF07724, AAA_2, score 3.7e-82
679897006334	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006335	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
679897006336	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
679897006337	Substrate binding site; other site
679897006338	Cupin domain; Region: Cupin_2; cl17218
679897006339	HMMPfam hit to PF00483, NTP_transferase, score 5.9e-63
679897006340	HMMPfam hit to PF01050, MannoseP_isomer, score 6.9e-87
679897006341	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
679897006342	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
679897006343	NADP-binding site; other site
679897006344	homotetramer interface [polypeptide binding]; other site
679897006345	substrate binding site [chemical binding]; other site
679897006346	homodimer interface [polypeptide binding]; other site
679897006347	active site
679897006348	HMMPfam hit to PF01370, Epimerase, score 5.5e-106
679897006349	PS00061 Short-chain dehydrogenases/reductases family signature.
679897006350	Predicted membrane protein [Function unknown]; Region: COG3059
679897006351	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006352	4 probable transmembrane helices predicted for HMU13190 by TMHMM2.0 at aa 12-34, 89-111, 113-135 and 155-177
679897006353	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
679897006354	8 probable transmembrane helices predicted for HMU13200 by TMHMM2.0 at aa 10-32, 45-67, 77-95, 102-121, 158-189, 196-218, 228-250 and 257-276
679897006355	ThiS-like ubiquitin; Region: ThiS-like; pfam14453
679897006356	thiamine biosynthesis protein ThiF; Provisional; Region: PRK08644
679897006357	E1_ThiF_like. Member of superfamily of activating enzymes (E1) of the ubiquitin-like proteins. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like substrate, on...; Region: E1_ThiF_like; cd01487
679897006358	putative ATP binding site [chemical binding]; other site
679897006359	putative substrate interface [chemical binding]; other site
679897006360	HMMPfam hit to PF00899, ThiF, score 6.2e-43
679897006361	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
679897006362	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
679897006363	dimer interface [polypeptide binding]; other site
679897006364	putative functional site; other site
679897006365	putative MPT binding site; other site
679897006366	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006367	HMMPfam hit to PF00994, MoCF_biosynth, score 4.6e-36
679897006368	PS01079 Molybdenum cofactor biosynthesis proteins signature 2.
679897006369	HMMPfam hit to PF03453, MoeA_N, score 1.5e-48
679897006370	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
679897006371	HMMPfam hit to PF01311, Bac_export_1, score 3.4e-60
679897006372	5 probable transmembrane helices predicted for HMU13230 by TMHMM2.0 at aa 15-32, 39-61, 76-98, 179-201 and 221-243
679897006373	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
679897006374	HD domain; Region: HD_3; pfam13023
679897006375	ribonuclease Y; Region: RNase_Y; TIGR03319
679897006376	KH domain; Region: KH_1; pfam00013
679897006377	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
679897006378	Zn2+ binding site [ion binding]; other site
679897006379	Mg2+ binding site [ion binding]; other site
679897006380	HMMPfam hit to PF01966, HD, score 5.2e-22
679897006381	HMMPfam hit to PF00013, KH_1, score 0.0016
679897006382	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
679897006383	HMMPfam hit to PF01812, 5-FTHF_cyc-lig, score 8.5e-08
679897006384	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
679897006385	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006386	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
679897006387	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
679897006388	P loop; other site
679897006389	GTP binding site [chemical binding]; other site
679897006390	HMMPfam hit to PF00448, SRP54, score 1.6e-98
679897006391	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006392	DNA repair protein RadA; Provisional; Region: PRK11823
679897006393	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
679897006394	Walker A motif; other site
679897006395	ATP binding site [chemical binding]; other site
679897006396	Walker B motif; other site
679897006397	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
679897006398	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006399	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
679897006400	Ligand Binding Site [chemical binding]; other site
679897006401	HMMPfam hit to PF00582, Usp, score 2.6e-10
679897006402	RmuC family; Region: RmuC; pfam02646
679897006403	Signal peptide predicted for HMU13310 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.812 between residues 32 and 33
679897006404	1 probable transmembrane helix predicted for HMU13310 by TMHMM2.0 at aa 2-24
679897006405	HMMPfam hit to PF02646, RmuC, score 1e-48
679897006406	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
679897006407	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
679897006408	catalytic residue [active]
679897006409	putative FPP diphosphate  binding site; other site
679897006410	putative FPP binding hydrophobic cleft; other site
679897006411	dimer interface [polypeptide binding]; other site
679897006412	putative IPP diphosphate binding site; other site
679897006413	HMMPfam hit to PF01255, Prenyltransf, score 4.5e-111
679897006414	PS01066 Undecaprenyl pyrophosphate synthetase family signature.
679897006415	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
679897006416	primosome assembly protein PriA; Validated; Region: PRK05580
679897006417	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
679897006418	ATP binding site [chemical binding]; other site
679897006419	putative Mg++ binding site [ion binding]; other site
679897006420	helicase superfamily c-terminal domain; Region: HELICc; smart00490
679897006421	HMMPfam hit to PF00270, DEAD, score 8.2e-09
679897006422	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006423	HMMPfam hit to PF00271, Helicase_C, score 0.00027
679897006424	triosephosphate isomerase; Provisional; Region: PRK14567
679897006425	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
679897006426	substrate binding site [chemical binding]; other site
679897006427	dimer interface [polypeptide binding]; other site
679897006428	catalytic triad [active]
679897006429	HMMPfam hit to PF00121, TIM, score 2.4e-81
679897006430	PS00171 Triosephosphate isomerase active site.
679897006431	PS00107 Protein kinases ATP-binding region signature.
679897006432	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
679897006433	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
679897006434	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
679897006435	trimer interface [polypeptide binding]; other site
679897006436	active site
679897006437	UDP-GlcNAc binding site [chemical binding]; other site
679897006438	lipid binding site [chemical binding]; lipid-binding site
679897006439	HMMPfam hit to PF04613, LpxD, score 4.6e-27
679897006440	HMMPfam hit to PF00132, Hexapep, score 10
679897006441	HMMPfam hit to PF00132, Hexapep, score 0.0038
679897006442	HMMPfam hit to PF00132, Hexapep, score 0.00048
679897006443	HMMPfam hit to PF00132, Hexapep, score 0.018
679897006444	HMMPfam hit to PF00132, Hexapep, score 1.2
679897006445	HMMPfam hit to PF00132, Hexapep, score 15
679897006446	HMMPfam hit to PF00132, Hexapep, score 3.6
679897006447	HMMPfam hit to PF00132, Hexapep, score 26
679897006448	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
679897006449	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
679897006450	HMMPfam hit to PF00311, PEPcase, score 8.6e-24
679897006451	PS00393 Phosphoenolpyruvate carboxylase active site 2.
679897006452	PS00781 Phosphoenolpyruvate carboxylase active site 1.
679897006453	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
679897006454	4 probable transmembrane helices predicted for HMU13390 by TMHMM2.0 at aa 4-21, 30-52, 56-78 and 85-102
679897006455	HMMPfam hit to PF00893, Multi_Drug_Res, score 2e-18
679897006456	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
679897006457	4 probable transmembrane helices predicted for HMU13400 by TMHMM2.0 at aa 7-29, 33-55, 60-82 and 86-108
679897006458	HMMPfam hit to PF00893, Multi_Drug_Res, score 1.7e-08
679897006459	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
679897006460	HMMPfam hit to PF01790, LGT, score 7.1e-93
679897006461	7 probable transmembrane helices predicted for HMU13410 by TMHMM2.0 at aa 23-45, 64-86, 106-128, 135-157, 187-209, 216-233 and 248-270
679897006462	PS01311 Prolipoprotein diacylglyceryl transferase signature.
679897006463	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
679897006464	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
679897006465	active site
679897006466	HMMPfam hit to PF00849, PseudoU_synth_2, score 1.2e-30
679897006467	PS01129 Rlu family of pseudouridine synthase signature.
679897006468	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
679897006469	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
679897006470	HMMPfam hit to PF04413, Glycos_transf_N, score 6.8e-58
679897006471	Signal peptide predicted for HMU13440 by SignalP 2.0 HMM (Signal peptide probability 0.975) with cleavage site probability 0.751 between residues 28 and 29
679897006472	1 probable transmembrane helix predicted for HMU13440 by TMHMM2.0 at aa 7-26
679897006473	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
679897006474	Putative zinc ribbon domain; Region: DUF164; pfam02591
679897006475	Uncharacterized conserved protein [Function unknown]; Region: COG0327
679897006476	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
679897006477	HMMPfam hit to PF01784, NIF3, score 2.3e-56
679897006478	putative recombination protein RecB; Provisional; Region: PRK13909
679897006479	Part of AAA domain; Region: AAA_19; pfam13245
679897006480	Family description; Region: UvrD_C_2; pfam13538
679897006481	HMMPfam hit to PF00580, UvrD-helicase, score 3e-16
679897006482	HMMPfam hit to PF00580, UvrD-helicase, score 2.3e-16
679897006483	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006484	Signal peptide predicted for HMU13480 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.367 between residues 20 and 21
679897006485	1 probable transmembrane helix predicted for HMU13480 by TMHMM2.0 at aa 4-21
679897006486	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
679897006487	tetramer interfaces [polypeptide binding]; other site
679897006488	binuclear metal-binding site [ion binding]; other site
679897006489	HMMPfam hit to PF04608, PgpA, score 3.8e-48
679897006490	4 probable transmembrane helices predicted for HMU13490 by TMHMM2.0 at aa 20-39, 44-62, 86-108 and 129-151
679897006491	PUA-like domain; Region: PUA_2; pfam14306
679897006492	ATP-sulfurylase; Region: ATP-sulfurylase; pfam01747
679897006493	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
679897006494	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
679897006495	active site
679897006496	phosphorylation site [posttranslational modification]
679897006497	dimerization interface [polypeptide binding]; other site
679897006498	Protein of unknown function, DUF603; Region: DUF603; pfam04645
679897006499	HMMPfam hit to PF02954, HTH_8, score 8.8e-05
679897006500	HMMPfam hit to PF00072, Response_reg, score 7.9e-10
679897006501	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
679897006502	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
679897006503	substrate binding site; other site
679897006504	dimer interface; other site
679897006505	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
679897006506	homotrimer interaction site [polypeptide binding]; other site
679897006507	zinc binding site [ion binding]; other site
679897006508	CDP-binding sites; other site
679897006509	HMMPfam hit to PF02542, YgbB, score 6.7e-69
679897006510	HMMPfam hit to PF01128, IspD, score 1.2e-09
679897006511	excinuclease ABC subunit B; Provisional; Region: PRK05298
679897006512	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
679897006513	ATP binding site [chemical binding]; other site
679897006514	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
679897006515	nucleotide binding region [chemical binding]; other site
679897006516	ATP-binding site [chemical binding]; other site
679897006517	Ultra-violet resistance protein B; Region: UvrB; pfam12344
679897006518	UvrB/uvrC motif; Region: UVR; pfam02151
679897006519	HMMPfam hit to PF02151, UVR, score 5.8e-10
679897006520	HMMPfam hit to PF00271, Helicase_C, score 5e-18
679897006521	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006522	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
679897006523	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
679897006524	metal-binding site [ion binding]
679897006525	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
679897006526	Soluble P-type ATPase [General function prediction only]; Region: COG4087
679897006527	HMMPfam hit to PF00403, HMA, score 0.0019
679897006528	PS01047 Heavy-metal-associated domain.
679897006529	5 probable transmembrane helices predicted for HMU13540 by TMHMM2.0 at aa 79-101, 111-130, 313-335, 350-372 and 645-667
679897006530	HMMPfam hit to PF00122, E1-E2_ATPase, score 5.7e-58
679897006531	HMMPfam hit to PF00702, Hydrolase, score 3.1e-25
679897006532	PS00154 E1-E2 ATPases phosphorylation site.
679897006533	PS01229 Hypothetical cof family signature 2.
679897006534	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
679897006535	HMMPfam hit to PF01856, HP_OMP, score 1.7e-12
679897006536	Signal peptide predicted for HMU13550 by SignalP 2.0 HMM (Signal peptide probability 0.985) with cleavage site probability 0.339 between residues 17 and 18
679897006537	Signal peptide predicted for HMU13570 by SignalP 2.0 HMM (Signal peptide probability 0.663) with cleavage site probability 0.275 between residues 54 and 55
679897006538	3 probable transmembrane helices predicted for HMU13570 by TMHMM2.0 at aa 126-148, 169-191 and 211-233
679897006539	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006540	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
679897006541	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
679897006542	Walker A/P-loop; other site
679897006543	ATP binding site [chemical binding]; other site
679897006544	Q-loop/lid; other site
679897006545	ABC transporter signature motif; other site
679897006546	Walker B; other site
679897006547	D-loop; other site
679897006548	H-loop/switch region; other site
679897006549	HMMPfam hit to PF00005, ABC_tran, score 2.1e-50
679897006550	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006551	PS00211 ABC transporters family signature.
679897006552	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
679897006553	mce related protein; Region: MCE; pfam02470
679897006554	Signal peptide predicted for HMU13590 by SignalP 2.0 HMM (Signal peptide probability 0.739) with cleavage site probability 0.402 between residues 33 and 34
679897006555	1 probable transmembrane helix predicted for HMU13590 by TMHMM2.0 at aa 7-29
679897006556	HMMPfam hit to PF02470, MCE, score 4.4e-11
679897006557	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
679897006558	Signal peptide predicted for HMU13600 by SignalP 2.0 HMM (Signal peptide probability 0.956) with cleavage site probability 0.794 between residues 26 and 27
679897006559	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006560	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
679897006561	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
679897006562	putative substrate translocation pore; other site
679897006563	11 probable transmembrane helices predicted for HMU13610 by TMHMM2.0 at aa 21-43, 53-75, 87-109, 155-177, 184-203, 232-254, 267-289, 299-318, 325-347, 357-379 and 391-410
679897006564	HMMPfam hit to PF07690, MFS_1, score 4.5e-23
679897006565	PS00217 Sugar transport proteins signature 2.
679897006566	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
679897006567	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
679897006568	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
679897006569	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
679897006570	HMMPfam hit to PF00005, ABC_tran, score 2e-23
679897006571	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006572	PS00211 ABC transporters family signature.
679897006573	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006574	PS00211 ABC transporters family signature.
679897006575	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006576	Domain of unknown function (DUF4198); Region: DUF4198; pfam10670
679897006577	2 probable transmembrane helices predicted for HMU13630 by TMHMM2.0 at aa 10-32 and 60-77
679897006578	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
679897006579	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
679897006580	HMMPfam hit to PF01027, UPF0005, score 3e-27
679897006581	6 probable transmembrane helices predicted for HMU13640 by TMHMM2.0 at aa 23-40, 47-69, 74-96, 108-127, 131-150 and 167-189
679897006582	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
679897006583	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
679897006584	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
679897006585	HMMPfam hit to PF00044, Gp_dh_N, score 6.1e-66
679897006586	PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site.
679897006587	HMMPfam hit to PF02800, Gp_dh_C, score 3.2e-64
679897006588	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
679897006589	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
679897006590	inhibitor-cofactor binding pocket; inhibition site
679897006591	pyridoxal 5'-phosphate binding site [chemical binding]; other site
679897006592	catalytic residue [active]
679897006593	HMMPfam hit to PF01041, DegT_DnrJ_EryC1, score 5.1e-98
679897006594	Signal peptide predicted for HMU13670 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.580 between residues 30 and 31
679897006595	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006596	S-methylmethionine transporter; Provisional; Region: PRK11387
679897006597	HMMPfam hit to PF00324, AA_permease, score 3.1e-122
679897006598	12 probable transmembrane helices predicted for HMU13680 by TMHMM2.0 at aa 17-36, 51-73, 94-116, 126-148, 160-182, 202-224, 237-259, 279-301, 332-354, 358-380, 401-423 and 428-447
679897006599	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006600	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
679897006601	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
679897006602	Walker A/P-loop; other site
679897006603	ATP binding site [chemical binding]; other site
679897006604	Q-loop/lid; other site
679897006605	ABC transporter signature motif; other site
679897006606	Walker B; other site
679897006607	D-loop; other site
679897006608	H-loop/switch region; other site
679897006609	ABC transporter; Region: ABC_tran_2; pfam12848
679897006610	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
679897006611	HMMPfam hit to PF00005, ABC_tran, score 3.2e-44
679897006612	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006613	HMMPfam hit to PF00005, ABC_tran, score 1.4e-36
679897006614	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006615	Outer membrane efflux protein; Region: OEP; pfam02321
679897006616	Outer membrane efflux protein; Region: OEP; pfam02321
679897006617	Signal peptide predicted for HMU13700 by SignalP 2.0 HMM (Signal peptide probability 0.911) with cleavage site probability 0.512 between residues 22 and 23
679897006618	HMMPfam hit to PF02321, OEP, score 5.5e-12
679897006619	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
679897006620	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
679897006621	HlyD family secretion protein; Region: HlyD_3; pfam13437
679897006622	1 probable transmembrane helix predicted for HMU13710 by TMHMM2.0 at aa 158-180
679897006623	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
679897006624	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
679897006625	7 probable transmembrane helices predicted for HMU13720 by TMHMM2.0 at aa 15-34, 179-201, 211-233, 246-268, 278-295, 302-320 and 330-352
679897006626	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
679897006627	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
679897006628	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
679897006629	6 probable transmembrane helices predicted for HMU13730 by TMHMM2.0 at aa 13-35, 184-206, 226-248, 263-285, 294-316 and 352-369
679897006630	HMMPfam hit to PF01061, ABC2_membrane, score 0.0025
679897006631	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
679897006632	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
679897006633	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
679897006634	HMMPfam hit to PF01420, Methylase_S, score 1.5e-44
679897006635	HMMPfam hit to PF01420, Methylase_S, score 1.8e-22
679897006636	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
679897006637	HMMPfam hit to PF00873, ACR_tran, score 3.3e-177
679897006638	12 probable transmembrane helices predicted for HMU13760 by TMHMM2.0 at aa 12-31, 334-356, 358-380, 385-407, 437-459, 474-496, 522-544, 864-881, 888-910, 914-936, 970-989 and 999-1021
679897006639	Signal peptide predicted for HMU13760 by SignalP 2.0 HMM (Signal peptide probability 0.974) with cleavage site probability 0.622 between residues 38 and 39
679897006640	HlyD family secretion protein; Region: HlyD_3; pfam13437
679897006641	Outer membrane efflux protein; Region: OEP; pfam02321
679897006642	Signal peptide predicted for HMU13780 by SignalP 2.0 HMM (Signal peptide probability 0.931) with cleavage site probability 0.777 between residues 21 and 22
679897006643	YtkA-like; Region: YtkA; pfam13115
679897006644	PS00430 TonB-dependent receptor proteins signature 1.
679897006645	Signal peptide predicted for HMU13790 by SignalP 2.0 HMM (Signal peptide probability 0.902) with cleavage site probability 0.403 between residues 18 and 19
679897006646	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
679897006647	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
679897006648	dimer interface [polypeptide binding]; other site
679897006649	phosphorylation site [posttranslational modification]
679897006650	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
679897006651	ATP binding site [chemical binding]; other site
679897006652	Mg2+ binding site [ion binding]; other site
679897006653	G-X-G motif; other site
679897006654	HMMPfam hit to PF02518, HATPase_c, score 5.3e-16
679897006655	HMMPfam hit to PF00512, HisKA, score 1.4e-08
679897006656	2 probable transmembrane helices predicted for HMU13800 by TMHMM2.0 at aa 4-22 and 172-194
679897006657	Signal peptide predicted for HMU13800 by SignalP 2.0 HMM (Signal peptide probability 0.812) with cleavage site probability 0.443 between residues 29 and 30
679897006658	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
679897006659	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
679897006660	active site
679897006661	phosphorylation site [posttranslational modification]
679897006662	intermolecular recognition site; other site
679897006663	dimerization interface [polypeptide binding]; other site
679897006664	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
679897006665	DNA binding site [nucleotide binding]
679897006666	HMMPfam hit to PF00486, Trans_reg_C, score 6.3e-15
679897006667	HMMPfam hit to PF00072, Response_reg, score 7.8e-30
679897006668	argininosuccinate synthase; Provisional; Region: PRK13820
679897006669	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
679897006670	ANP binding site [chemical binding]; other site
679897006671	Substrate Binding Site II [chemical binding]; other site
679897006672	Substrate Binding Site I [chemical binding]; other site
679897006673	HMMPfam hit to PF00764, Arginosuc_synth, score 1.4e-200
679897006674	PS00565 Argininosuccinate synthase signature 2.
679897006675	PS00564 Argininosuccinate synthase signature 1.
679897006676	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
679897006677	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
679897006678	Sulfatase; Region: Sulfatase; pfam00884
679897006679	5 probable transmembrane helices predicted for HMU13830 by TMHMM2.0 at aa 5-27, 42-64, 69-87, 118-137 and 150-172
679897006680	HMMPfam hit to PF00884, Sulfatase, score 5.2e-50
679897006681	DNA polymerase I; Provisional; Region: PRK05755
679897006682	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
679897006683	active site
679897006684	metal binding site 1 [ion binding]; metal-binding site
679897006685	putative 5' ssDNA interaction site; other site
679897006686	metal binding site 3; metal-binding site
679897006687	metal binding site 2 [ion binding]; metal-binding site
679897006688	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
679897006689	putative DNA binding site [nucleotide binding]; other site
679897006690	putative metal binding site [ion binding]; other site
679897006691	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
679897006692	active site
679897006693	catalytic site [active]
679897006694	substrate binding site [chemical binding]; other site
679897006695	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
679897006696	active site
679897006697	DNA binding site [nucleotide binding]
679897006698	catalytic site [active]
679897006699	HMMPfam hit to PF00476, DNA_pol_A, score 4.9e-122
679897006700	PS00447 DNA polymerase family A signature.
679897006701	HMMPfam hit to PF01612, 3_5_exonuc, score 5.2e-20
679897006702	HMMPfam hit to PF01367, 5_3_exonuc, score 2.5e-37
679897006703	HMMPfam hit to PF02739, 5_3_exonuc_N, score 1.1e-50
679897006704	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
679897006705	HMMPfam hit to PF02511, Thy1, score 2.5e-55
679897006706	tellurite resistance protein TehB; Provisional; Region: PRK11207
679897006707	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897006708	S-adenosylmethionine binding site [chemical binding]; other site
679897006709	HMMPfam hit to PF08242, Methyltransf_12, score 0.00082
679897006710	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
679897006711	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
679897006712	12 probable transmembrane helices predicted for HMU13870 by TMHMM2.0 at aa 21-43, 53-75, 96-118, 142-164, 171-193, 203-225, 246-268, 283-305, 318-340, 360-379, 392-414 and 418-440
679897006713	HMMPfam hit to PF01554, MatE, score 2.8e-12
679897006714	HMMPfam hit to PF01554, MatE, score 5.5e-33
679897006715	fumarate reductase cytochrome b-556 subunit; Provisional; Region: PRK13553
679897006716	Quinol:fumarate reductase (QFR) Type B subfamily, transmembrane subunit;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinone...; Region: QFR_TypeB_TM; cd00581
679897006717	Iron-sulfur protein interface; other site
679897006718	proximal heme binding site [chemical binding]; other site
679897006719	distal heme binding site [chemical binding]; other site
679897006720	dimer interface [polypeptide binding]; other site
679897006721	HMMPfam hit to PF02967, Fum_red_TM, score 2.2e-150
679897006722	5 probable transmembrane helices predicted for HMU13880 by TMHMM2.0 at aa 32-54, 75-97, 125-147, 168-190 and 210-232
679897006723	fumarate reductase flavoprotein subunit; Provisional; Region: PRK08626
679897006724	L-aspartate oxidase; Provisional; Region: PRK06175
679897006725	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
679897006726	HMMPfam hit to PF00890, FAD_binding_2, score 3.2e-160
679897006727	PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site.
679897006728	HMMPfam hit to PF02910, Succ_DH_flav_C, score 2.7e-61
679897006729	fumarate reductase iron-sulfur subunit; Provisional; Region: frdB; PRK13552
679897006730	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
679897006731	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
679897006732	PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature.
679897006733	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006734	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
679897006735	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
679897006736	Walker A/P-loop; other site
679897006737	ATP binding site [chemical binding]; other site
679897006738	Q-loop/lid; other site
679897006739	ABC transporter signature motif; other site
679897006740	Walker B; other site
679897006741	D-loop; other site
679897006742	H-loop/switch region; other site
679897006743	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
679897006744	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
679897006745	HMMPfam hit to PF00005, ABC_tran, score 3.3e-69
679897006746	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006747	PS00211 ABC transporters family signature.
679897006748	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
679897006749	dimer interface [polypeptide binding]; other site
679897006750	conserved gate region; other site
679897006751	ABC-ATPase subunit interface; other site
679897006752	HMMPfam hit to PF00528, BPD_transp_1, score 5.2e-10
679897006753	5 probable transmembrane helices predicted for HMU13920 by TMHMM2.0 at aa 15-37, 50-72, 77-99, 141-163 and 183-205
679897006754	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
679897006755	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
679897006756	Signal peptide predicted for HMU13930 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.813 between residues 32 and 33
679897006757	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006758	HMMPfam hit to PF03180, Lipoprotein_9, score 2e-99
679897006759	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
679897006760	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
679897006761	Signal peptide predicted for HMU13940 by SignalP 2.0 HMM (Signal peptide probability 0.682) with cleavage site probability 0.253 between residues 25 and 26
679897006762	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897006763	HMMPfam hit to PF03180, Lipoprotein_9, score 2e-114
679897006764	PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature.
679897006765	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
679897006766	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
679897006767	Coenzyme A binding pocket [chemical binding]; other site
679897006768	HMMPfam hit to PF00583, Acetyltransf_1, score 1.5e-18
679897006769	Signal peptide predicted for HMU13950 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.449 between residues 34 and 35
679897006770	1 probable transmembrane helix predicted for HMU13950 by TMHMM2.0 at aa 10-27
679897006771	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
679897006772	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
679897006773	active site
679897006774	substrate binding site [chemical binding]; other site
679897006775	metal binding site [ion binding]; metal-binding site
679897006776	HMMPfam hit to PF00408, PGM_PMM_IV, score 9.5e-13
679897006777	HMMPfam hit to PF02880, PGM_PMM_III, score 2.3e-18
679897006778	HMMPfam hit to PF02879, PGM_PMM_II, score 1.5e-23
679897006779	HMMPfam hit to PF02878, PGM_PMM_I, score 5.6e-37
679897006780	PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature.
679897006781	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
679897006782	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
679897006783	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
679897006784	HMMPfam hit to PF00593, TonB_dep_Rec, score 0.00024
679897006785	HMMPfam hit to PF07715, Plug, score 1.8e-07
679897006786	Signal peptide predicted for HMU13980 by SignalP 2.0 HMM (Signal peptide probability 0.669) with cleavage site probability 0.187 between residues 21 and 22
679897006787	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
679897006788	heterotetramer interface [polypeptide binding]; other site
679897006789	active site pocket [active]
679897006790	cleavage site
679897006791	HMMPfam hit to PF01960, ArgJ, score 2.8e-130
679897006792	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
679897006793	Signal peptide predicted for HMU14010 by SignalP 2.0 HMM (Signal peptide probability 0.964) with cleavage site probability 0.682 between residues 16 and 17
679897006794	7-alpha-hydroxysteroid dehydrogenase; Provisional; Region: PRK08416
679897006795	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
679897006796	putative NAD(P) binding site [chemical binding]; other site
679897006797	active site
679897006798	HMMPfam hit to PF00106, adh_short, score 7.9e-06
679897006799	dihydrodipicolinate synthase; Region: dapA; TIGR00674
679897006800	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
679897006801	dimer interface [polypeptide binding]; other site
679897006802	active site
679897006803	catalytic residue [active]
679897006804	HMMPfam hit to PF00701, DHDPS, score 4.6e-93
679897006805	PS00666 Dihydrodipicolinate synthetase signature 2.
679897006806	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
679897006807	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
679897006808	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
679897006809	HMMPfam hit to PF05193, Peptidase_M16_C, score 3.3e-40
679897006810	HMMPfam hit to PF00675, Peptidase_M16, score 1.7e-18
679897006811	PS00143 Insulinase family, zinc-binding region signature.
679897006812	Signal peptide predicted for HMU14040 by SignalP 2.0 HMM (Signal peptide probability 0.915) with cleavage site probability 0.399 between residues 16 and 17
679897006813	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
679897006814	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
679897006815	quinone interaction residues [chemical binding]; other site
679897006816	active site
679897006817	catalytic residues [active]
679897006818	FMN binding site [chemical binding]; other site
679897006819	substrate binding site [chemical binding]; other site
679897006820	HMMPfam hit to PF01180, DHO_dh, score 6.3e-71
679897006821	PS00912 Dihydroorotate dehydrogenase signature 2.
679897006822	PS00911 Dihydroorotate dehydrogenase signature 1.
679897006823	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
679897006824	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
679897006825	trimer interface [polypeptide binding]; other site
679897006826	putative metal binding site [ion binding]; other site
679897006827	HMMPfam hit to PF00132, Hexapep, score 0.1
679897006828	HMMPfam hit to PF00132, Hexapep, score 0.0057
679897006829	HMMPfam hit to PF00132, Hexapep, score 1.1e+02
679897006830	HMMPfam hit to PF00132, Hexapep, score 57
679897006831	Protein of unknown function, DUF; Region: DUF411; cl01142
679897006832	Signal peptide predicted for HMU14070 by SignalP 2.0 HMM (Signal peptide probability 0.925) with cleavage site probability 0.801 between residues 33 and 34
679897006833	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
679897006834	active site
679897006835	catalytic site [active]
679897006836	substrate binding site [chemical binding]; other site
679897006837	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108
679897006838	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
679897006839	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
679897006840	catalytic residues [active]
679897006841	HMMPfam hit to PF00085, Thioredoxin, score 1.4e-16
679897006842	Predicted membrane protein [Function unknown]; Region: COG2855
679897006843	10 probable transmembrane helices predicted for HMU14100 by TMHMM2.0 at aa 5-27, 31-50, 89-111, 121-140, 152-174, 187-209, 221-238, 253-275, 287-309 and 319-341
679897006844	HMMPfam hit to PF03601, Cons_hypoth698, score 6e-102
679897006845	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
679897006846	active site 2 [active]
679897006847	active site 1 [active]
679897006848	Methyltransferase domain; Region: Methyltransf_23; pfam13489
679897006849	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
679897006850	S-adenosylmethionine binding site [chemical binding]; other site
679897006851	HMMPfam hit to PF08003, Methyltransf_9, score 2.4e-77
679897006852	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
679897006853	PS01037 Bacterial extracellular solute-binding proteins, family 1 signature.
679897006854	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
679897006855	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
679897006856	active site
679897006857	HIGH motif; other site
679897006858	KMSKS motif; other site
679897006859	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
679897006860	tRNA binding surface [nucleotide binding]; other site
679897006861	anticodon binding site; other site
679897006862	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
679897006863	dimer interface [polypeptide binding]; other site
679897006864	putative tRNA-binding site [nucleotide binding]; other site
679897006865	HMMPfam hit to PF01588, tRNA_bind, score 1.1e-36
679897006866	HMMPfam hit to PF09334, tRNA-synt_1g, score 1.2e-207
679897006867	Selenocysteine-specific translation elongation factor [Translation, ribosomal structure and biogenesis]; Region: SelB; COG3276
679897006868	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
679897006869	G1 box; other site
679897006870	putative GEF interaction site [polypeptide binding]; other site
679897006871	GTP/Mg2+ binding site [chemical binding]; other site
679897006872	Switch I region; other site
679897006873	G2 box; other site
679897006874	G3 box; other site
679897006875	Switch II region; other site
679897006876	G4 box; other site
679897006877	G5 box; other site
679897006878	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
679897006879	Domain III of Elongation factor (EF) Tu (EF-TU) and EF-G.  Elongation factors (EF) EF-Tu and EF-G participate in the elongation phase during protein biosynthesis on the ribosome. Their functional cycles depend on GTP binding and its hydrolysis. The EF-Tu...; Region: Translation_factor_III; cl02786
679897006880	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
679897006881	HMMPfam hit to PF03144, GTP_EFTU_D2, score 1.3e-07
679897006882	HMMPfam hit to PF00009, GTP_EFTU, score 1.9e-32
679897006883	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006884	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
679897006885	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
679897006886	dimer interface [polypeptide binding]; other site
679897006887	active site
679897006888	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
679897006889	catalytic residues [active]
679897006890	substrate binding site [chemical binding]; other site
679897006891	HMMPfam hit to PF00278, Orn_DAP_Arg_deC, score 2.1e-28
679897006892	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
679897006893	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
679897006894	Response regulator receiver domain; Region: Response_reg; pfam00072
679897006895	active site
679897006896	phosphorylation site [posttranslational modification]
679897006897	intermolecular recognition site; other site
679897006898	dimerization interface [polypeptide binding]; other site
679897006899	HMMPfam hit to PF00072, Response_reg, score 2.4e-15
679897006900	HMMPfam hit to PF01584, CheW, score 2.3e-18
679897006901	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
679897006902	FeS/SAM binding site; other site
679897006903	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
679897006904	HMMPfam hit to PF04055, Radical_SAM, score 0.021
679897006905	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
679897006906	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
679897006907	5 probable transmembrane helices predicted for HMU14200 by TMHMM2.0 at aa 13-35, 45-67, 95-117, 127-149 and 161-183
679897006908	flavodoxin FldA; Validated; Region: PRK09267
679897006909	HMMPfam hit to PF00258, Flavodoxin_1, score 1.3e-31
679897006910	PS00201 Flavodoxin signature.
679897006911	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
679897006912	4Fe-4S binding domain; Region: Fer4_5; pfam12801
679897006913	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
679897006914	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
679897006915	5 probable transmembrane helices predicted for HMU14220 by TMHMM2.0 at aa 48-66, 93-115, 168-190, 205-227 and 343-365
679897006916	HMMPfam hit to PF00037, Fer4, score 0.01
679897006917	PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature.
679897006918	PS00190 Cytochrome c family heme-binding site signature.
679897006919	glutamine synthetase, type I; Region: GlnA; TIGR00653
679897006920	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
679897006921	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
679897006922	HMMPfam hit to PF00120, Gln-synt_C, score 1.7e-158
679897006923	PS00181 Glutamine synthetase  ATP-binding region signature.
679897006924	HMMPfam hit to PF03951, Gln-synt_N, score 1.3e-35
679897006925	PS00213 Lipocalin signature.
679897006926	1 probable transmembrane helix predicted for HMU14240 by TMHMM2.0 at aa 48-70
679897006927	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
679897006928	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
679897006929	Signal peptide predicted for HMU14250 by SignalP 2.0 HMM (Signal peptide probability 0.879) with cleavage site probability 0.674 between residues 34 and 35
679897006930	1 probable transmembrane helix predicted for HMU14250 by TMHMM2.0 at aa 10-29
679897006931	HMMPfam hit to PF07963, N_methyl, score 9.7e-07
679897006932	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
679897006933	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
679897006934	HMMPfam hit to PF01048, PNP_UDP_1, score 2.4e-68
679897006935	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
679897006936	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
679897006937	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006938	HMMPfam hit to PF00698, Acyl_transf_1, score 0.00021
679897006939	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
679897006940	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
679897006941	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
679897006942	3 probable transmembrane helices predicted for HMU14300 by TMHMM2.0 at aa 159-181, 207-229 and 363-385
679897006943	HMMPfam hit to PF00482, GSPII_F, score 1.7e-14
679897006944	HMMPfam hit to PF00482, GSPII_F, score 4.7e-10
679897006945	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
679897006946	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
679897006947	Walker A motif; other site
679897006948	ATP binding site [chemical binding]; other site
679897006949	Walker B motif; other site
679897006950	PS00012 Phosphopantetheine attachment site.
679897006951	HMMPfam hit to PF00437, GSPII_E, score 1.3e-62
679897006952	PS00662 Bacterial type II secretion system protein E signature.
679897006953	PS00017 ATP/GTP-binding site motif A (P-loop).
679897006954	1 probable transmembrane helix predicted for HMU14320 by TMHMM2.0 at aa 7-25
679897006955	1 probable transmembrane helix predicted for HMU14350 by TMHMM2.0 at aa 20-39
679897006956	1 probable transmembrane helix predicted for HMU14360 by TMHMM2.0 at aa 184-206
679897006957	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
679897006958	Ferritin-like domain; Region: Ferritin; pfam00210
679897006959	ferroxidase diiron center [ion binding]; other site
679897006960	HMMPfam hit to PF00210, Ferritin, score 1.2e-44
679897006961	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
679897006962	dihydroorotase; Provisional; Region: PRK08417
679897006963	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
679897006964	active site
679897006965	Mechanosensitive ion channel; Region: MS_channel; pfam00924
679897006966	3 probable transmembrane helices predicted for HMU14390 by TMHMM2.0 at aa 15-37, 57-79 and 94-116
679897006967	HMMPfam hit to PF00924, MS_channel, score 2.9e-75
679897006968	chlorohydrolase; Provisional; Region: PRK08418
679897006969	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
679897006970	active site
679897006971	HMMPfam hit to PF01979, Amidohydro_1, score 2e-27
679897006972	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
679897006973	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
679897006974	glutaminase active site [active]
679897006975	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
679897006976	dimer interface [polypeptide binding]; other site
679897006977	active site
679897006978	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
679897006979	dimer interface [polypeptide binding]; other site
679897006980	active site
679897006981	PS00443 Glutamine amidotransferases class-II active site.
679897006982	HMMPfam hit to PF00310, GATase_2, score 1.6e-31
679897006983	HMMPfam hit to PF01380, SIS, score 1.4e-31
679897006984	HMMPfam hit to PF01380, SIS, score 5e-07
679897006985	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
679897006986	active site
679897006987	homotetramer interface [polypeptide binding]; other site
679897006988	homodimer interface [polypeptide binding]; other site
679897006989	HMMPfam hit to PF00710, Asparaginase, score 2e-85
679897006990	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
679897006991	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
679897006992	active site
679897006993	HIGH motif; other site
679897006994	nucleotide binding site [chemical binding]; other site
679897006995	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
679897006996	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
679897006997	active site
679897006998	KMSKS motif; other site
679897006999	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
679897007000	tRNA binding surface [nucleotide binding]; other site
679897007001	anticodon binding site; other site
679897007002	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
679897007003	HMMPfam hit to PF00133, tRNA-synt_1, score 7.1e-278
679897007004	PS00178 Aminoacyl-transfer RNA synthetases class-I signature.
679897007005	PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
679897007006	HMMPfam hit to PF08264, Anticodon_1, score 4.5e-15
679897007007	HMMPfam hit to PF06827, zf-FPG_IleRS, score 1.2e-06
679897007008	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
679897007009	active site
679897007010	putative DNA-binding cleft [nucleotide binding]; other site
679897007011	dimer interface [polypeptide binding]; other site
679897007012	HMMPfam hit to PF02075, RuvC, score 1.4e-71