-- dump date   	20140619_112642
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
585535000001	7-cyano-7-deazaguanine reductase; Region: QueF-II; TIGR03139
585535000002	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
585535000003	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
585535000004	tRNA dimethylallyltransferase; Region: miaA; TIGR00174
585535000005	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
585535000006	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
585535000007	Ligand binding site; other site
585535000008	metal-binding site
585535000009	Adenine-specific methyltransferase EcoRI; Region: EcoRI_methylase; pfam13651
585535000010	Restriction endonuclease EcoRI; Region: EcoRI; pfam02963
585535000011	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13904
585535000012	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
585535000013	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
585535000014	flagellum-specific ATP synthase; Validated; Region: fliI; PRK08472
585535000015	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
585535000016	Walker A motif/ATP binding site; other site
585535000017	Walker B motif; other site
585535000018	Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis [Cell motility and secretion / Intracellular trafficking and secretion]; Region: VirB11; COG0630
585535000019	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
585535000020	Walker A motif; other site
585535000021	hexamer interface [polypeptide binding]; other site
585535000022	ATP binding site [chemical binding]; other site
585535000023	Walker B motif; other site
585535000024	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
585535000025	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
585535000026	active site
585535000027	HIGH motif; other site
585535000028	nucleotide binding site [chemical binding]; other site
585535000029	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
585535000030	active site
585535000031	KMSKS motif; other site
585535000032	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
585535000033	tRNA binding surface [nucleotide binding]; other site
585535000034	anticodon binding site; other site
585535000035	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585535000036	RNA binding surface [nucleotide binding]; other site
585535000037	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14462
585535000038	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585535000039	FeS/SAM binding site; other site
585535000040	KpsF/GutQ family protein; Region: kpsF; TIGR00393
585535000041	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
585535000042	putative active site [active]
585535000043	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
585535000044	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
585535000045	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
585535000046	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
585535000047	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
585535000048	dimethyladenosine transferase; Region: ksgA; TIGR00755
585535000049	formyltetrahydrofolate deformylase; Region: PurU; TIGR00655
585535000050	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
585535000051	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
585535000052	active site
585535000053	substrate binding site [chemical binding]; other site
585535000054	cosubstrate binding site; other site
585535000055	catalytic site [active]
585535000056	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
585535000057	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
585535000058	tandem repeat interface [polypeptide binding]; other site
585535000059	oligomer interface [polypeptide binding]; other site
585535000060	active site residues [active]
585535000061	TIR domain; Region: TIR_2; cl17458
585535000062	enterobactin exporter EntS; Provisional; Region: PRK10489
585535000063	rod shape-determining protein MreC; Provisional; Region: PRK13922
585535000064	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
585535000065	active site
585535000066	carbon storage regulator; Provisional; Region: PRK00568
585535000067	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK04181
585535000068	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
585535000069	SmpB-tmRNA interface; other site
585535000070	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
585535000071	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
585535000072	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
585535000073	ribonuclease P protein component, eubacterial; Region: rnpA; TIGR00188
585535000074	hypothetical protein; Provisional; Region: PRK14374
585535000075	membrane protein insertase; Provisional; Region: PRK01318
585535000076	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
585535000077	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
585535000078	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
585535000079	tRNA modification GTPase TrmE; Region: mnmE_trmE_thdF; TIGR00450
585535000080	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
585535000081	GTP/Mg2+ binding site [chemical binding]; other site
585535000082	G4 box; other site
585535000083	G5 box; other site
585535000084	trmE is a tRNA modification GTPase; Region: trmE; cd04164
585535000085	G1 box; other site
585535000086	G1 box; other site
585535000087	GTP/Mg2+ binding site [chemical binding]; other site
585535000088	Switch I region; other site
585535000089	Switch I region; other site
585535000090	G2 box; other site
585535000091	G2 box; other site
585535000092	Switch II region; other site
585535000093	G3 box; other site
585535000094	G3 box; other site
585535000095	Switch II region; other site
585535000096	G4 box; other site
585535000097	G5 box; other site
585535000098	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
585535000099	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535000100	LPP20 lipoprotein; Region: LPP20; pfam02169
585535000101	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
585535000102	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
585535000103	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
585535000104	catalytic residues [active]
585535000105	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
585535000106	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585535000107	RNA binding surface [nucleotide binding]; other site
585535000108	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
585535000109	active site
585535000110	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
585535000111	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
585535000112	active site
585535000113	PHP Thumb interface [polypeptide binding]; other site
585535000114	metal binding site [ion binding]; metal-binding site
585535000115	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
585535000116	generic binding surface I; other site
585535000117	generic binding surface II; other site
585535000118	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
585535000119	Heat shock protein [Posttranslational modification, protein turnover, chaperones]; Region: HslJ; COG3187
585535000120	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
585535000121	mce related protein; Region: MCE; pfam02470
585535000122	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
585535000123	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
585535000124	Walker A/P-loop; other site
585535000125	ATP binding site [chemical binding]; other site
585535000126	Q-loop/lid; other site
585535000127	ABC transporter signature motif; other site
585535000128	Walker B; other site
585535000129	D-loop; other site
585535000130	H-loop/switch region; other site
585535000131	conserved hypothetical integral membrane protein; Region: TIGR00056
585535000132	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
585535000133	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535000134	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
585535000135	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
585535000136	homodimer interface [polypeptide binding]; other site
585535000137	substrate-cofactor binding pocket; other site
585535000138	catalytic residue [active]
585535000139	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535000140	DNA polymerase I; Region: pola; TIGR00593
585535000141	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
585535000142	active site
585535000143	metal binding site 1 [ion binding]; metal-binding site
585535000144	putative 5' ssDNA interaction site; other site
585535000145	metal binding site 3; metal-binding site
585535000146	metal binding site 2 [ion binding]; metal-binding site
585535000147	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
585535000148	putative DNA binding site [nucleotide binding]; other site
585535000149	putative metal binding site [ion binding]; other site
585535000150	3'-5' exonuclease; Region: 35EXOc; smart00474
585535000151	active site
585535000152	substrate binding site [chemical binding]; other site
585535000153	catalytic site [active]
585535000154	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
585535000155	active site
585535000156	DNA binding site [nucleotide binding]
585535000157	catalytic site [active]
585535000158	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
585535000159	thymidylate kinase; Validated; Region: tmk; PRK00698
585535000160	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
585535000161	TMP-binding site; other site
585535000162	ATP-binding site [chemical binding]; other site
585535000163	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
585535000164	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
585535000165	active site
585535000166	(T/H)XGH motif; other site
585535000167	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
585535000168	Flavoprotein; Region: Flavoprotein; pfam02441
585535000169	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK08515
585535000170	flagella basal body P-ring formation protein FlgA; Region: flgA_cterm; TIGR03170
585535000171	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
585535000172	Part of AAA domain; Region: AAA_19; pfam13245
585535000173	Family description; Region: UvrD_C_2; pfam13538
585535000174	TPR repeat; Region: TPR_11; pfam13414
585535000175	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585535000176	TPR motif; other site
585535000177	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585535000178	binding surface
585535000179	TPR motif; other site
585535000180	seryl-tRNA synthetase; Provisional; Region: PRK05431
585535000181	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
585535000182	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
585535000183	dimer interface [polypeptide binding]; other site
585535000184	active site
585535000185	motif 1; other site
585535000186	motif 2; other site
585535000187	motif 3; other site
585535000188	Predicted amidohydrolase [General function prediction only]; Region: COG0388
585535000189	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
585535000190	active site
585535000191	catalytic triad [active]
585535000192	dimer interface [polypeptide binding]; other site
585535000193	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK14065
585535000194	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
585535000195	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585535000196	S-adenosylmethionine binding site [chemical binding]; other site
585535000197	Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863
585535000198	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
585535000199	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
585535000200	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
585535000201	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
585535000202	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
585535000203	ABC-2 type transporter; Region: ABC2_membrane; cl17235
585535000204	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585535000205	HlyD family secretion protein; Region: HlyD_3; pfam13437
585535000206	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
585535000207	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
585535000208	Domain of unknown function DUF21; Region: DUF21; pfam01595
585535000209	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
585535000210	Transporter associated domain; Region: CorC_HlyC; smart01091
585535000211	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
585535000212	Phosphate transporter family; Region: PHO4; pfam01384
585535000213	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
585535000214	UDP-N-acetylmuramyl-tripeptide synthetase; Region: murE; TIGR01085
585535000215	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585535000216	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585535000217	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
585535000218	putative active site [active]
585535000219	transaldolase; Provisional; Region: PRK03903
585535000220	catalytic residue [active]
585535000221	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
585535000222	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
585535000223	5S rRNA interface [nucleotide binding]; other site
585535000224	CTC domain interface [polypeptide binding]; other site
585535000225	L16 interface [polypeptide binding]; other site
585535000226	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
585535000227	putative active site [active]
585535000228	catalytic residue [active]
585535000229	Predicted permeases [General function prediction only]; Region: COG0795
585535000230	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
585535000231	Catalytic domain of type II restriction endonucleases BfiI and NgoFVII, and uncharacterized proteins with a DEAD domain; Region: PLDc_Bfil_DEXD_like; cd09117
585535000232	PLD-like domain; Region: PLDc_2; pfam13091
585535000233	homodimer interface [polypeptide binding]; other site
585535000234	putative active site [active]
585535000235	catalytic site [active]
585535000236	Uncharacterized conserved protein (DUF2161); Region: DUF2161; cl02298
585535000237	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535000238	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3399
585535000239	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
585535000240	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
585535000241	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
585535000242	metal-binding site [ion binding]
585535000243	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
585535000244	Soluble P-type ATPase [General function prediction only]; Region: COG4087
585535000245	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
585535000246	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585535000247	S-adenosylmethionine binding site [chemical binding]; other site
585535000248	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
585535000249	catalytic motif [active]
585535000250	Zn binding site [ion binding]; other site
585535000251	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
585535000252	RibD C-terminal domain; Region: RibD_C; cl17279
585535000253	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
585535000254	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
585535000255	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
585535000256	NAD(P) binding pocket [chemical binding]; other site
585535000257	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
585535000258	4Fe-4S binding domain; Region: Fer4_5; pfam12801
585535000259	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
585535000260	acyl-phosphate glycerol 3-phosphate acyltransferase; Region: TIGR00023
585535000261	FolB domain; Region: folB_dom; TIGR00526
585535000262	active site
585535000263	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
585535000264	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
585535000265	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
585535000266	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
585535000267	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
585535000268	transcription elongation factor NusA; Provisional; Region: nusA; PRK12328
585535000269	NusA N-terminal domain; Region: NusA_N; pfam08529
585535000270	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
585535000271	RNA binding site [nucleotide binding]; other site
585535000272	homodimer interface [polypeptide binding]; other site
585535000273	NusA-like KH domain; Region: KH_5; pfam13184
585535000274	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
585535000275	G-X-X-G motif; other site
585535000276	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
585535000277	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
585535000278	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
585535000279	Restriction endonuclease [Defense mechanisms]; Region: COG3587
585535000280	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585535000281	ATP binding site [chemical binding]; other site
585535000282	putative Mg++ binding site [ion binding]; other site
585535000283	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
585535000284	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
585535000285	DNA methylase; Region: N6_N4_Mtase; cl17433
585535000286	DNA methylase; Region: N6_N4_Mtase; pfam01555
585535000287	DNA methylase; Region: N6_N4_Mtase; cl17433
585535000288	ATP-dependent DNA helicase RecG; Region: recG; TIGR00643
585535000289	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
585535000290	ssDNA binding site; other site
585535000291	generic binding surface II; other site
585535000292	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585535000293	ATP binding site [chemical binding]; other site
585535000294	putative Mg++ binding site [ion binding]; other site
585535000295	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585535000296	nucleotide binding region [chemical binding]; other site
585535000297	ATP-binding site [chemical binding]; other site
585535000298	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535000299	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
585535000300	active site
585535000301	putative catalytic site [active]
585535000302	DNA binding site [nucleotide binding]
585535000303	putative phosphate binding site [ion binding]; other site
585535000304	metal binding site A [ion binding]; metal-binding site
585535000305	AP binding site [nucleotide binding]; other site
585535000306	metal binding site B [ion binding]; metal-binding site
585535000307	Protein interacting with poly(A)-binding protein [RNA processing and modification]; Region: PBP1; COG5180
585535000308	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
585535000309	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535000310	Walker A motif; other site
585535000311	ATP binding site [chemical binding]; other site
585535000312	Walker B motif; other site
585535000313	arginine finger; other site
585535000314	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
585535000315	DnaA box-binding interface [nucleotide binding]; other site
585535000316	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
585535000317	Protein of unknown function (DUF2443); Region: DUF2443; pfam10398
585535000318	glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Region: glmS; TIGR01135
585535000319	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
585535000320	glutaminase active site [active]
585535000321	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
585535000322	dimer interface [polypeptide binding]; other site
585535000323	active site
585535000324	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
585535000325	dimer interface [polypeptide binding]; other site
585535000326	active site
585535000327	Predicted alternative thymidylate synthase [Nucleotide transport and metabolism]; Region: THY1; COG1351
585535000328	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
585535000329	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
585535000330	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
585535000331	HsdM N-terminal domain; Region: HsdM_N; pfam12161
585535000332	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
585535000333	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
585535000334	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
585535000335	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585535000336	ATP binding site [chemical binding]; other site
585535000337	putative Mg++ binding site [ion binding]; other site
585535000338	Protein of unknown function DUF45; Region: DUF45; pfam01863
585535000339	Arginase family; Region: Arginase; cd09989
585535000340	active site
585535000341	Mn binding site [ion binding]; other site
585535000342	oligomer interface [polypeptide binding]; other site
585535000343	S-methylmethionine transporter; Provisional; Region: PRK11387
585535000344	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
585535000345	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
585535000346	hexamer interface [polypeptide binding]; other site
585535000347	ligand binding site [chemical binding]; other site
585535000348	putative active site [active]
585535000349	NAD(P) binding site [chemical binding]; other site
585535000350	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535000351	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
585535000352	ATP-NAD kinase; Region: NAD_kinase; pfam01513
585535000353	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
585535000354	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585535000355	Walker A/P-loop; other site
585535000356	ATP binding site [chemical binding]; other site
585535000357	Q-loop/lid; other site
585535000358	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
585535000359	ABC transporter signature motif; other site
585535000360	Walker B; other site
585535000361	D-loop; other site
585535000362	H-loop/switch region; other site
585535000363	Domain of unknown function (DUF814); Region: DUF814; pfam05670
585535000364	DNA polymerase III subunit epsilon; Provisional; Region: PRK08517
585535000365	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
585535000366	active site
585535000367	catalytic site [active]
585535000368	substrate binding site [chemical binding]; other site
585535000369	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
585535000370	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
585535000371	substrate binding site [chemical binding]; other site
585535000372	hexamer interface [polypeptide binding]; other site
585535000373	metal binding site [ion binding]; metal-binding site
585535000374	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
585535000375	active site
585535000376	Methyltransferase domain; Region: Methyltransf_26; pfam13659
585535000377	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
585535000378	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
585535000379	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
585535000380	cofactor binding site; other site
585535000381	elongation factor Ts; Provisional; Region: tsf; PRK09377
585535000382	UBA/TS-N domain; Region: UBA; pfam00627
585535000383	Elongation factor TS; Region: EF_TS; pfam00889
585535000384	Elongation factor TS; Region: EF_TS; pfam00889
585535000385	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
585535000386	rRNA interaction site [nucleotide binding]; other site
585535000387	S8 interaction site; other site
585535000388	putative laminin-1 binding site; other site
585535000389	putative recombination protein RecB; Provisional; Region: PRK13909
585535000390	Family description; Region: UvrD_C_2; pfam13538
585535000391	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
585535000392	pH-dependent sodium/proton antiporter; Provisional; Region: nhaA; PRK14856
585535000393	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
585535000394	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
585535000395	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
585535000396	protein-export membrane protein SecF; Region: 3a0501s07; TIGR00966
585535000397	Protein export membrane protein; Region: SecD_SecF; pfam02355
585535000398	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
585535000399	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
585535000400	HIGH motif; other site
585535000401	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
585535000402	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
585535000403	active site
585535000404	KMSKS motif; other site
585535000405	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
585535000406	tRNA binding surface [nucleotide binding]; other site
585535000407	anticodon binding site; other site
585535000408	Lipopolysaccharide-assembly; Region: LptE; pfam04390
585535000409	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
585535000410	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585535000411	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585535000412	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
585535000413	Peptidase family M23; Region: Peptidase_M23; pfam01551
585535000414	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
585535000415	Peptidase family M23; Region: Peptidase_M23; pfam01551
585535000416	variable size of poly A (7A/6A) between reads; Unresolved repeat
585535000417	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
585535000418	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
585535000419	transcription-repair coupling factor (mfd); Region: mfd; TIGR00580
585535000420	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
585535000421	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585535000422	ATP binding site [chemical binding]; other site
585535000423	putative Mg++ binding site [ion binding]; other site
585535000424	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585535000425	nucleotide binding region [chemical binding]; other site
585535000426	ATP-binding site [chemical binding]; other site
585535000427	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
585535000428	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
585535000429	Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470
585535000430	[2Fe-2S] cluster binding site [ion binding]; other site
585535000431	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
585535000432	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
585535000433	intrachain domain interface; other site
585535000434	interchain domain interface [polypeptide binding]; other site
585535000435	heme bH binding site [chemical binding]; other site
585535000436	Qi binding site; other site
585535000437	heme bL binding site [chemical binding]; other site
585535000438	Qo binding site; other site
585535000439	interchain domain interface [polypeptide binding]; other site
585535000440	intrachain domain interface; other site
585535000441	Qi binding site; other site
585535000442	Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032
585535000443	Qo binding site; other site
585535000444	Cytochrome c1 [Energy production and conversion]; Region: CYT1; COG2857
585535000445	Cytochrome c; Region: Cytochrom_C; pfam00034
585535000446	Cytochrome c; Region: Cytochrom_C; cl11414
585535000447	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
585535000448	Predicted ATPases [General function prediction only]; Region: COG1106
585535000449	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585535000450	Walker A/P-loop; other site
585535000451	ATP binding site [chemical binding]; other site
585535000452	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
585535000453	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
585535000454	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
585535000455	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK03907
585535000456	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
585535000457	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
585535000458	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
585535000459	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
585535000460	Cell cycle protein; Region: FTSW_RODA_SPOVE; pfam01098
585535000461	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
585535000462	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
585535000463	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
585535000464	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
585535000465	dimer interface [polypeptide binding]; other site
585535000466	decamer (pentamer of dimers) interface [polypeptide binding]; other site
585535000467	catalytic triad [active]
585535000468	peroxidatic and resolving cysteines [active]
585535000469	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
585535000470	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
585535000471	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
585535000472	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
585535000473	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
585535000474	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
585535000475	G1 box; other site
585535000476	GTP/Mg2+ binding site [chemical binding]; other site
585535000477	Switch I region; other site
585535000478	G2 box; other site
585535000479	G3 box; other site
585535000480	Switch II region; other site
585535000481	G4 box; other site
585535000482	G5 box; other site
585535000483	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
585535000484	OstA-like protein; Region: OstA; pfam03968
585535000485	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585535000486	motif II; other site
585535000487	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
585535000488	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
585535000489	Sporulation related domain; Region: SPOR; pfam05036
585535000490	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585535000491	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585535000492	catalytic residue [active]
585535000493	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585535000494	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
585535000495	active site
585535000496	riboflavin synthase, alpha subunit; Region: ribE; TIGR00187
585535000497	Lumazine binding domain; Region: Lum_binding; pfam00677
585535000498	Lumazine binding domain; Region: Lum_binding; pfam00677
585535000499	flhB C-terminus-related protein; Region: flhB_rel; TIGR00789
585535000500	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
585535000501	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
585535000502	Walker A/P-loop; other site
585535000503	ATP binding site [chemical binding]; other site
585535000504	Q-loop/lid; other site
585535000505	ABC transporter signature motif; other site
585535000506	Walker B; other site
585535000507	D-loop; other site
585535000508	H-loop/switch region; other site
585535000509	NIL domain; Region: NIL; pfam09383
585535000510	ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]; Region: AbcD; COG2011
585535000511	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
585535000512	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
585535000513	active site
585535000514	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
585535000515	This subfamily is composed of uncharacterized bacterial glycosyltransferases in the MraY-like family. This family contains both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases, which...; Region: GT_MraY_like; cd06912
585535000516	Mg++ binding site [ion binding]; other site
585535000517	putative catalytic motif [active]
585535000518	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
585535000519	active site
585535000520	hydrophilic channel; other site
585535000521	dimerization interface [polypeptide binding]; other site
585535000522	catalytic residues [active]
585535000523	active site lid [active]
585535000524	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
585535000525	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK03946
585535000526	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
585535000527	metallohydrolase, glycoprotease/Kae1 family; Region: gcp_kae1; TIGR00329
585535000528	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
585535000529	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
585535000530	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
585535000531	hypothetical protein; Provisional; Region: PRK10236
585535000532	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
585535000533	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
585535000534	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
585535000535	putative RNA binding site [nucleotide binding]; other site
585535000536	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
585535000537	homopentamer interface [polypeptide binding]; other site
585535000538	active site
585535000539	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
585535000540	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
585535000541	active site clefts [active]
585535000542	zinc binding site [ion binding]; other site
585535000543	dimer interface [polypeptide binding]; other site
585535000544	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
585535000545	active site
585535000546	dimer interface [polypeptide binding]; other site
585535000547	pantoate--beta-alanine ligase; Region: panC; TIGR00018
585535000548	Pantoate-beta-alanine ligase; Region: PanC; cd00560
585535000549	active site
585535000550	ATP-binding site [chemical binding]; other site
585535000551	pantoate-binding site; other site
585535000552	HXXH motif; other site
585535000553	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535000554	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
585535000555	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
585535000556	ring oligomerisation interface [polypeptide binding]; other site
585535000557	ATP/Mg binding site [chemical binding]; other site
585535000558	stacking interactions; other site
585535000559	hinge regions; other site
585535000560	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
585535000561	oligomerisation interface [polypeptide binding]; other site
585535000562	mobile loop; other site
585535000563	roof hairpin; other site
585535000564	DNA primase, catalytic core; Region: dnaG; TIGR01391
585535000565	CHC2 zinc finger; Region: zf-CHC2; pfam01807
585535000566	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
585535000567	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
585535000568	active site
585535000569	metal binding site [ion binding]; metal-binding site
585535000570	interdomain interaction site; other site
585535000571	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
585535000572	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
585535000573	Ligand Binding Site [chemical binding]; other site
585535000574	TrbC/VIRB2 family; Region: TrbC; cl01583
585535000575	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
585535000576	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
585535000577	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
585535000578	Walker A motif; other site
585535000579	ATP binding site [chemical binding]; other site
585535000580	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
585535000581	Walker B motif; other site
585535000582	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
585535000583	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
585535000584	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
585535000585	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585535000586	active site
585535000587	phosphorylation site [posttranslational modification]
585535000588	intermolecular recognition site; other site
585535000589	dimerization interface [polypeptide binding]; other site
585535000590	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
585535000591	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
585535000592	dimer interface [polypeptide binding]; other site
585535000593	active site
585535000594	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585535000595	catalytic residues [active]
585535000596	substrate binding site [chemical binding]; other site
585535000597	lipid A 1-phosphatase; Reviewed; Region: PRK09597
585535000598	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
585535000599	active site
585535000600	lipid A phosphoethanolamine transferase; Reviewed; Region: PRK09598
585535000601	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
585535000602	Sulfatase; Region: Sulfatase; pfam00884
585535000603	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535000604	DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism]; Region: NUC1; COG1864
585535000605	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
585535000606	prephenate dehydrogenase; Validated; Region: PRK08507
585535000607	Prephenate dehydrogenase; Region: PDH; pfam02153
585535000608	ATP-dependent protease La; Region: lon; TIGR00763
585535000609	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535000610	Walker A motif; other site
585535000611	ATP binding site [chemical binding]; other site
585535000612	Walker B motif; other site
585535000613	arginine finger; other site
585535000614	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
585535000615	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
585535000616	flagellar assembly protein FliW; Provisional; Region: PRK13282
585535000617	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
585535000618	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
585535000619	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
585535000620	active site
585535000621	endopeptidase Clp ATP-binding regulatory subunit (clpX); Region: clpX; TIGR00382
585535000622	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
585535000623	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
585535000624	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535000625	Walker A motif; other site
585535000626	ATP binding site [chemical binding]; other site
585535000627	Walker B motif; other site
585535000628	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
585535000629	rod shape-determining protein MreB; Provisional; Region: PRK13927
585535000630	MreB and similar proteins; Region: MreB_like; cd10225
585535000631	nucleotide binding site [chemical binding]; other site
585535000632	Mg binding site [ion binding]; other site
585535000633	putative protofilament interaction site [polypeptide binding]; other site
585535000634	RodZ interaction site [polypeptide binding]; other site
585535000635	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
585535000636	rod shape-determining protein MreC; Region: MreC; pfam04085
585535000637	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
585535000638	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
585535000639	DNA methylase; Region: N6_N4_Mtase; pfam01555
585535000640	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
585535000641	DNA methylase; Region: N6_N4_Mtase; pfam01555
585535000642	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
585535000643	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585535000644	active site
585535000645	phosphorylation site [posttranslational modification]
585535000646	intermolecular recognition site; other site
585535000647	dimerization interface [polypeptide binding]; other site
585535000648	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585535000649	DNA binding site [nucleotide binding]
585535000650	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
585535000651	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
585535000652	dimer interface [polypeptide binding]; other site
585535000653	phosphorylation site [posttranslational modification]
585535000654	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585535000655	ATP binding site [chemical binding]; other site
585535000656	Mg2+ binding site [ion binding]; other site
585535000657	G-X-G motif; other site
585535000658	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
585535000659	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
585535000660	putative substrate binding site [chemical binding]; other site
585535000661	putative ATP binding site [chemical binding]; other site
585535000662	replicative DNA helicase; Provisional; Region: PRK08506
585535000663	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
585535000664	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
585535000665	Walker A motif; other site
585535000666	ATP binding site [chemical binding]; other site
585535000667	Walker B motif; other site
585535000668	DNA binding loops [nucleotide binding]
585535000669	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
585535000670	Competence protein; Region: Competence; pfam03772
585535000671	prenyltransferase; Reviewed; Region: ubiA; PRK12874
585535000672	UbiA prenyltransferase family; Region: UbiA; pfam01040
585535000673	RNA polymerase factor sigma-70; Validated; Region: PRK06811
585535000674	phosphatidylserine decarboxylase; Provisional; Region: PRK03934
585535000675	Quinolinate synthetase A protein; Region: NadA; cl00420
585535000676	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK05848
585535000677	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
585535000678	dimerization interface [polypeptide binding]; other site
585535000679	active site
585535000680	Predicted helicase [General function prediction only]; Region: COG4889
585535000681	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
585535000682	DNA methylase; Region: N6_N4_Mtase; pfam01555
585535000683	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
585535000684	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
585535000685	C-terminal peptidase (prc); Region: prc; TIGR00225
585535000686	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
585535000687	protein binding site [polypeptide binding]; other site
585535000688	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
585535000689	Catalytic dyad [active]
585535000690	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
585535000691	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
585535000692	putative acyl-acceptor binding pocket; other site
585535000693	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
585535000694	ligand binding site [chemical binding]; other site
585535000695	active site
585535000696	UGI interface [polypeptide binding]; other site
585535000697	catalytic site [active]
585535000698	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
585535000699	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
585535000700	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
585535000701	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
585535000702	Phosphoglycerate kinase; Region: PGK; pfam00162
585535000703	substrate binding site [chemical binding]; other site
585535000704	hinge regions; other site
585535000705	ADP binding site [chemical binding]; other site
585535000706	catalytic site [active]
585535000707	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
585535000708	Mg2+ transporter Helicobacter pylori CorA-like subgroup; Region: HpCorA-like; cd12836
585535000709	Cl binding site [ion binding]; other site
585535000710	oligomer interface [polypeptide binding]; other site
585535000711	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
585535000712	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
585535000713	DNA methylase; Region: N6_N4_Mtase; pfam01555
585535000714	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
585535000715	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
585535000716	DNA binding site [nucleotide binding]
585535000717	substrate interaction site [chemical binding]; other site
585535000718	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
585535000719	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
585535000720	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
585535000721	Na binding site [ion binding]; other site
585535000722	Proline dehydrogenase; Region: Pro_dh; pfam01619
585535000723	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
585535000724	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
585535000725	Glutamate binding site [chemical binding]; other site
585535000726	NAD binding site [chemical binding]; other site
585535000727	catalytic residues [active]
585535000728	Proteins of 100 residues with WXG; Region: WXG100; cl02005
585535000729	DNase/tRNase domain of colicin-like bacteriocin; Region: Colicin-DNase; cl15861
585535000730	Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829
585535000731	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
585535000732	G1 box; other site
585535000733	GTP/Mg2+ binding site [chemical binding]; other site
585535000734	G2 box; other site
585535000735	Switch I region; other site
585535000736	G3 box; other site
585535000737	Switch II region; other site
585535000738	G4 box; other site
585535000739	G5 box; other site
585535000740	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
585535000741	UreF; Region: UreF; pfam01730
585535000742	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
585535000743	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
585535000744	dimer interface [polypeptide binding]; other site
585535000745	catalytic residues [active]
585535000746	AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293
585535000747	urease subunit beta; Provisional; Region: ureB; PRK13985
585535000748	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
585535000749	subunit interactions [polypeptide binding]; other site
585535000750	active site
585535000751	flap region; other site
585535000752	urease subunit alpha; Provisional; Region: PRK13986
585535000753	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
585535000754	alpha-gamma subunit interface [polypeptide binding]; other site
585535000755	beta-gamma subunit interface [polypeptide binding]; other site
585535000756	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
585535000757	gamma-beta subunit interface [polypeptide binding]; other site
585535000758	alpha-beta subunit interface [polypeptide binding]; other site
585535000759	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
585535000760	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14324
585535000761	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
585535000762	active site
585535000763	substrate binding site [chemical binding]; other site
585535000764	metal binding site [ion binding]; metal-binding site
585535000765	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
585535000766	peptide chain release factor 1; Validated; Region: prfA; PRK00591
585535000767	This domain is found in peptide chain release factors; Region: PCRF; smart00937
585535000768	RF-1 domain; Region: RF-1; pfam00472
585535000769	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
585535000770	dimer interface [polypeptide binding]; other site
585535000771	putative CheW interface [polypeptide binding]; other site
585535000772	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
585535000773	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
585535000774	23S rRNA interface [nucleotide binding]; other site
585535000775	L3 interface [polypeptide binding]; other site
585535000776	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
585535000777	Predicted dehydrogenase [General function prediction only]; Region: COG0579
585535000778	NLPC_P60 stabilising domain, N term; Region: N_NLPC_P60; pfam12912
585535000779	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
585535000780	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
585535000781	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
585535000782	NlpC/P60 family; Region: NLPC_P60; pfam00877
585535000783	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
585535000784	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
585535000785	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
585535000786	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
585535000787	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
585535000788	DNA binding residues [nucleotide binding]
585535000789	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
585535000790	TOPRIM_TopoIA: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in the type IA family of DNA topoisomerases (TopoIA). This subgroup contains proteins similar to the Type I DNA topoisomerases: E. coli...; Region: TOPRIM_TopoIA; cd01028
585535000791	active site
585535000792	interdomain interaction site; other site
585535000793	putative metal-binding site [ion binding]; other site
585535000794	nucleotide binding site [chemical binding]; other site
585535000795	DNA topoisomerase; Region: Topoisom_bac; pfam01131
585535000796	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cl11986
585535000797	domain I; other site
585535000798	DNA binding groove [nucleotide binding]
585535000799	phosphate binding site [ion binding]; other site
585535000800	domain II; other site
585535000801	domain III; other site
585535000802	nucleotide binding site [chemical binding]; other site
585535000803	catalytic site [active]
585535000804	domain IV; other site
585535000805	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
585535000806	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535000807	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
585535000808	23S rRNA binding site [nucleotide binding]; other site
585535000809	L21 binding site [polypeptide binding]; other site
585535000810	L13 binding site [polypeptide binding]; other site
585535000811	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
585535000812	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
585535000813	translation initiation factor IF-3; Region: infC; TIGR00168
585535000814	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
585535000815	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
585535000816	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
585535000817	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
585535000818	active site
585535000819	dimer interface [polypeptide binding]; other site
585535000820	motif 1; other site
585535000821	motif 2; other site
585535000822	motif 3; other site
585535000823	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
585535000824	anticodon binding site; other site
585535000825	phosphoenolpyruvate synthase; Validated; Region: PRK06464
585535000826	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
585535000827	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
585535000828	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
585535000829	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
585535000830	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
585535000831	Fe-S oxidoreductases [Energy production and conversion]; Region: COG0731
585535000832	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585535000833	FeS/SAM binding site; other site
585535000834	DNA topoisomerase I; Validated; Region: PRK05582
585535000835	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
585535000836	active site
585535000837	interdomain interaction site; other site
585535000838	putative metal-binding site [ion binding]; other site
585535000839	nucleotide binding site [chemical binding]; other site
585535000840	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
585535000841	domain I; other site
585535000842	DNA binding groove [nucleotide binding]
585535000843	phosphate binding site [ion binding]; other site
585535000844	domain II; other site
585535000845	domain III; other site
585535000846	nucleotide binding site [chemical binding]; other site
585535000847	catalytic site [active]
585535000848	domain IV; other site
585535000849	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
585535000850	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
585535000851	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
585535000852	flagellin B; Provisional; Region: PRK13588
585535000853	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
585535000854	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
585535000855	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
585535000856	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
585535000857	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
585535000858	hypothetical protein; Provisional; Region: PRK05834
585535000859	heat-inducible transcription repressor; Provisional; Region: PRK03911
585535000860	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
585535000861	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
585535000862	dimer interface [polypeptide binding]; other site
585535000863	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
585535000864	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
585535000865	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
585535000866	nucleotide binding site [chemical binding]; other site
585535000867	NEF interaction site [polypeptide binding]; other site
585535000868	SBD interface [polypeptide binding]; other site
585535000869	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
585535000870	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
585535000871	dimer interface [polypeptide binding]; other site
585535000872	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585535000873	catalytic residue [active]
585535000874	cystathionine gamma-synthase/cystathionine beta-lyase; Validated; Region: PRK06176
585535000875	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
585535000876	homodimer interface [polypeptide binding]; other site
585535000877	substrate-cofactor binding pocket; other site
585535000878	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585535000879	catalytic residue [active]
585535000880	S-Ribosylhomocysteinase (LuxS); Region: LuxS; pfam02664
585535000881	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
585535000882	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
585535000883	active site
585535000884	metal binding site [ion binding]; metal-binding site
585535000885	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
585535000886	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
585535000887	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
585535000888	dimerization interface [polypeptide binding]; other site
585535000889	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
585535000890	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
585535000891	dimer interface [polypeptide binding]; other site
585535000892	putative CheW interface [polypeptide binding]; other site
585535000893	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
585535000894	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
585535000895	metal-binding site
585535000896	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535000897	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases and ATP sulphurylases. The domain forms a apha/beta/apha fold which  binds to Adenosine group; Region: Alpha_ANH_like; cd01986
585535000898	Ligand Binding Site [chemical binding]; other site
585535000899	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
585535000900	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
585535000901	dimer interface [polypeptide binding]; other site
585535000902	putative CheW interface [polypeptide binding]; other site
585535000903	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
585535000904	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
585535000905	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585535000906	catalytic residue [active]
585535000907	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
585535000908	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
585535000909	NAD binding site [chemical binding]; other site
585535000910	Alpha-1,2-fucosyltransferase; Region: Fut1_Fut2_like; cd11301
585535000911	Glycosyl transferase family 11; Region: Glyco_transf_11; pfam01531
585535000912	GDP-Fucose binding site [chemical binding]; other site
585535000913	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
585535000914	Methyltransferase domain; Region: Methyltransf_26; pfam13659
585535000915	DNA methylase; Region: N6_N4_Mtase; pfam01555
585535000916	DpnII restriction endonuclease; Region: DpnII; pfam04556
585535000917	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
585535000918	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
585535000919	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
585535000920	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
585535000921	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
585535000922	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
585535000923	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
585535000924	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
585535000925	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
585535000926	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
585535000927	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
585535000928	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroG; COG3200
585535000929	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
585535000930	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
585535000931	catalytic triad [active]
585535000932	Uncharacterized conserved protein [Function unknown]; Region: COG1556
585535000933	iron-sulfur cluster-binding protein; Region: TIGR00273
585535000934	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
585535000935	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
585535000936	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
585535000937	Cysteine-rich domain; Region: CCG; pfam02754
585535000938	Cysteine-rich domain; Region: CCG; pfam02754
585535000939	L-lactate transport; Region: lctP; TIGR00795
585535000940	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
585535000941	L-lactate transport; Region: lctP; TIGR00795
585535000942	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
585535000943	DNA glycosylase MutY; Provisional; Region: PRK13910
585535000944	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
585535000945	minor groove reading motif; other site
585535000946	helix-hairpin-helix signature motif; other site
585535000947	substrate binding pocket [chemical binding]; other site
585535000948	active site
585535000949	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
585535000950	DNA binding and oxoG recognition site [nucleotide binding]
585535000951	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
585535000952	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
585535000953	transmembrane helices; other site
585535000954	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
585535000955	Low-spin heme binding site [chemical binding]; other site
585535000956	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
585535000957	D-pathway; other site
585535000958	Putative water exit pathway; other site
585535000959	Binuclear center (active site) [active]
585535000960	K-pathway; other site
585535000961	Putative proton exit pathway; other site
585535000962	Cbb3-type cytochrome oxidase, cytochrome c subunit [Energy production and conversion]; Region: CcoO; COG2993
585535000963	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; cl01130
585535000964	cytochrome c oxidase, cbb3-type, CcoQ subunit, epsilon-Proteobacterial; Region: cbb3_Q_epsi; TIGR02736
585535000965	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
585535000966	Cytochrome c; Region: Cytochrom_C; pfam00034
585535000967	Cytochrome c; Region: Cytochrom_C; pfam00034
585535000968	Family of unknown function (DUF4006); Region: DUF4006; pfam13179
585535000969	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
585535000970	recombinase A; Provisional; Region: recA; PRK09354
585535000971	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
585535000972	hexamer interface [polypeptide binding]; other site
585535000973	Walker A motif; other site
585535000974	ATP binding site [chemical binding]; other site
585535000975	Walker B motif; other site
585535000976	enolase; Provisional; Region: eno; PRK00077
585535000977	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
585535000978	dimer interface [polypeptide binding]; other site
585535000979	metal binding site [ion binding]; metal-binding site
585535000980	substrate binding pocket [chemical binding]; other site
585535000981	AMIN domain; Region: AMIN; pfam11741
585535000982	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
585535000983	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
585535000984	ADP binding site [chemical binding]; other site
585535000985	magnesium binding site [ion binding]; other site
585535000986	putative shikimate binding site; other site
585535000987	Cache domain; Region: Cache_1; pfam02743
585535000988	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
585535000989	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
585535000990	Ligand binding site; other site
585535000991	metal-binding site
585535000992	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585535000993	Sel1-like repeats; Region: SEL1; smart00671
585535000994	Sel1-like repeats; Region: SEL1; smart00671
585535000995	Sel1-like repeats; Region: SEL1; smart00671
585535000996	Sel1-like repeats; Region: SEL1; smart00671
585535000997	Sel1-like repeats; Region: SEL1; smart00671
585535000998	Sel1-like repeats; Region: SEL1; smart00671
585535000999	hypothetical protein; Provisional; Region: PRK12378
585535001000	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
585535001001	dimer interface [polypeptide binding]; other site
585535001002	active site
585535001003	Schiff base residues; other site
585535001004	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
585535001005	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
585535001006	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585535001007	dimer interface [polypeptide binding]; other site
585535001008	phosphorylation site [posttranslational modification]
585535001009	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585535001010	ATP binding site [chemical binding]; other site
585535001011	Mg2+ binding site [ion binding]; other site
585535001012	G-X-G motif; other site
585535001013	variable size of poly G (13G/12G) between reads; Unresolved repeat
585535001014	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
585535001015	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585535001016	active site
585535001017	phosphorylation site [posttranslational modification]
585535001018	intermolecular recognition site; other site
585535001019	dimerization interface [polypeptide binding]; other site
585535001020	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585535001021	DNA binding site [nucleotide binding]
585535001022	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
585535001023	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
585535001024	Peptidase family U32; Region: Peptidase_U32; pfam01136
585535001025	peptide chain release factor 2; Region: prfB; TIGR00020
585535001026	This domain is found in peptide chain release factors; Region: PCRF; smart00937
585535001027	RF-1 domain; Region: RF-1; pfam00472
585535001028	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
585535001029	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
585535001030	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
585535001031	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
585535001032	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
585535001033	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
585535001034	intersubunit interface [polypeptide binding]; other site
585535001035	active site
585535001036	zinc binding site [ion binding]; other site
585535001037	Na+ binding site [ion binding]; other site
585535001038	elongation factor P; Validated; Region: PRK00529
585535001039	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
585535001040	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
585535001041	RNA binding site [nucleotide binding]; other site
585535001042	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
585535001043	RNA binding site [nucleotide binding]; other site
585535001044	pseudaminic acid synthase; Region: PseI; TIGR03586
585535001045	NeuB family; Region: NeuB; pfam03102
585535001046	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
585535001047	NeuB binding interface [polypeptide binding]; other site
585535001048	putative substrate binding site [chemical binding]; other site
585535001049	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
585535001050	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
585535001051	Walker A/P-loop; other site
585535001052	ATP binding site [chemical binding]; other site
585535001053	Q-loop/lid; other site
585535001054	ABC transporter signature motif; other site
585535001055	Walker B; other site
585535001056	D-loop; other site
585535001057	H-loop/switch region; other site
585535001058	apolipoprotein N-acyltransferase; Reviewed; Region: PRK12291
585535001059	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
585535001060	active site
585535001061	catalytic triad [active]
585535001062	variable size of poly T (TT/T*) between reads; Unresolved repeat
585535001063	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
585535001064	Colicin V production protein; Region: Colicin_V; pfam02674
585535001065	Apolipoprotein C-I (ApoC-1); Region: ApoC-I; pfam04691
585535001066	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
585535001067	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
585535001068	dimer interface [polypeptide binding]; other site
585535001069	putative anticodon binding site; other site
585535001070	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
585535001071	motif 1; other site
585535001072	active site
585535001073	motif 2; other site
585535001074	motif 3; other site
585535001075	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
585535001076	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
585535001077	dimer interface [polypeptide binding]; other site
585535001078	active site
585535001079	glycine-pyridoxal phosphate binding site [chemical binding]; other site
585535001080	folate binding site [chemical binding]; other site
585535001081	Domain of unknown function (DUF1882); Region: DUF1882; pfam08966
585535001082	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
585535001083	Protein of unknown function DUF262; Region: DUF262; pfam03235
585535001084	Uncharacterized conserved protein [Function unknown]; Region: COG1479
585535001085	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
585535001086	Uncharacterized protein family, UPF0114; Region: UPF0114; cl01078
585535001087	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
585535001088	PLD-like domain; Region: PLDc_2; pfam13091
585535001089	putative active site [active]
585535001090	catalytic site [active]
585535001091	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
585535001092	PLD-like domain; Region: PLDc_2; pfam13091
585535001093	putative active site [active]
585535001094	catalytic site [active]
585535001095	fumarate reductase iron-sulfur subunit; Provisional; Region: frdB; PRK13552
585535001096	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
585535001097	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585535001098	fumarate reductase flavoprotein subunit; Provisional; Region: PRK08626
585535001099	L-aspartate oxidase; Provisional; Region: PRK06175
585535001100	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
585535001101	fumarate reductase cytochrome b-556 subunit; Provisional; Region: PRK13553
585535001102	Quinol:fumarate reductase (QFR) Type B subfamily, transmembrane subunit;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinone...; Region: QFR_TypeB_TM; cd00581
585535001103	Iron-sulfur protein interface; other site
585535001104	proximal heme binding site [chemical binding]; other site
585535001105	distal heme binding site [chemical binding]; other site
585535001106	dimer interface [polypeptide binding]; other site
585535001107	triosephosphate isomerase; Provisional; Region: PRK14567
585535001108	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
585535001109	substrate binding site [chemical binding]; other site
585535001110	dimer interface [polypeptide binding]; other site
585535001111	catalytic triad [active]
585535001112	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08415
585535001113	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
585535001114	NAD binding site [chemical binding]; other site
585535001115	homotetramer interface [polypeptide binding]; other site
585535001116	homodimer interface [polypeptide binding]; other site
585535001117	substrate binding site [chemical binding]; other site
585535001118	active site
585535001119	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
585535001120	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
585535001121	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
585535001122	trimer interface [polypeptide binding]; other site
585535001123	active site
585535001124	UDP-GlcNAc binding site [chemical binding]; other site
585535001125	lipid binding site [chemical binding]; lipid-binding site
585535001126	S-adenosylmethionine synthetase; Validated; Region: PRK05250
585535001127	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
585535001128	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
585535001129	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
585535001130	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
585535001131	active site
585535001132	multimer interface [polypeptide binding]; other site
585535001133	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
585535001134	fatty acid/phospholipid synthesis protein PlsX; Region: plsX; TIGR00182
585535001135	3-oxoacyl-(acyl-carrier-protein) synthase III; Region: fabH; TIGR00747
585535001136	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
585535001137	dimer interface [polypeptide binding]; other site
585535001138	active site
585535001139	CoA binding pocket [chemical binding]; other site
585535001140	antiporter inner membrane protein; Provisional; Region: PRK11670
585535001141	Domain of unknown function DUF59; Region: DUF59; cl00941
585535001142	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
585535001143	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
585535001144	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
585535001145	Ligand binding site; other site
585535001146	metal-binding site
585535001147	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
585535001148	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
585535001149	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
585535001150	heat shock protein 90; Provisional; Region: PRK05218
585535001151	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585535001152	ATP binding site [chemical binding]; other site
585535001153	Mg2+ binding site [ion binding]; other site
585535001154	G-X-G motif; other site
585535001155	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585535001156	Sel1-like repeats; Region: SEL1; smart00671
585535001157	Sel1-like repeats; Region: SEL1; smart00671
585535001158	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585535001159	TPR motif; other site
585535001160	binding surface
585535001161	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
585535001162	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
585535001163	metal binding site [ion binding]; metal-binding site
585535001164	dimer interface [polypeptide binding]; other site
585535001165	glucose-inhibited division protein A; Region: gidA; TIGR00136
585535001166	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585535001167	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
585535001168	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
585535001169	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
585535001170	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
585535001171	transmembrane helices; other site
585535001172	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
585535001173	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
585535001174	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: Dxr; TIGR00243
585535001175	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
585535001176	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
585535001177	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
585535001178	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
585535001179	substrate binding site [chemical binding]; other site
585535001180	Helix-turn-helix domain; Region: HTH_28; pfam13518
585535001181	cysteine desulfurase, NifS family, epsilon proteobacteria type; Region: nifS_epsilon; TIGR03403
585535001182	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
585535001183	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585535001184	catalytic residue [active]
585535001185	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
585535001186	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
585535001187	trimerization site [polypeptide binding]; other site
585535001188	active site
585535001189	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
585535001190	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
585535001191	DNA repair protein RadA; Region: sms; TIGR00416
585535001192	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
585535001193	Walker A motif/ATP binding site; other site
585535001194	ATP binding site [chemical binding]; other site
585535001195	Walker B motif; other site
585535001196	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
585535001197	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
585535001198	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
585535001199	SelR domain; Region: SelR; pfam01641
585535001200	Predicted permeases [General function prediction only]; Region: COG0730
585535001201	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535001202	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
585535001203	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
585535001204	Sulfate transporter family; Region: Sulfate_transp; pfam00916
585535001205	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535001206	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
585535001207	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
585535001208	Ligand binding site; other site
585535001209	oligomer interface; other site
585535001210	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
585535001211	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
585535001212	hypothetical protein; Provisional; Region: PRK04081
585535001213	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
585535001214	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585535001215	Sel1-like repeats; Region: SEL1; smart00671
585535001216	Sel1-like repeats; Region: SEL1; smart00671
585535001217	Sel1-like repeats; Region: SEL1; smart00671
585535001218	Sel1-like repeats; Region: SEL1; smart00671
585535001219	Cytochrome c; Region: Cytochrom_C; cl11414
585535001220	Porphobilinogen deaminase [Coenzyme metabolism]; Region: HemC; COG0181
585535001221	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
585535001222	domain interfaces; other site
585535001223	active site
585535001224	prolyl-tRNA synthetase, family II; Region: proS_fam_II; TIGR00409
585535001225	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
585535001226	dimer interface [polypeptide binding]; other site
585535001227	motif 1; other site
585535001228	active site
585535001229	motif 2; other site
585535001230	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
585535001231	putative deacylase active site [active]
585535001232	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
585535001233	active site
585535001234	motif 3; other site
585535001235	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
585535001236	anticodon binding site; other site
585535001237	glutamyl-tRNA reductase; Region: hemA; TIGR01035
585535001238	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
585535001239	tRNA; other site
585535001240	putative tRNA binding site [nucleotide binding]; other site
585535001241	putative NADP binding site [chemical binding]; other site
585535001242	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
585535001243	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
585535001244	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
585535001245	substrate binding pocket [chemical binding]; other site
585535001246	chain length determination region; other site
585535001247	substrate-Mg2+ binding site; other site
585535001248	catalytic residues [active]
585535001249	aspartate-rich region 1; other site
585535001250	active site lid residues [active]
585535001251	aspartate-rich region 2; other site
585535001252	Domain of unknown function (DUF2018); Region: DUF2018; pfam09442
585535001253	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
585535001254	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
585535001255	dimerization interface [polypeptide binding]; other site
585535001256	DPS ferroxidase diiron center [ion binding]; other site
585535001257	ion pore; other site
585535001258	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
585535001259	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585535001260	dimer interface [polypeptide binding]; other site
585535001261	phosphorylation site [posttranslational modification]
585535001262	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585535001263	ATP binding site [chemical binding]; other site
585535001264	Mg2+ binding site [ion binding]; other site
585535001265	G-X-G motif; other site
585535001266	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
585535001267	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
585535001268	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
585535001269	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
585535001270	ATP binding site [chemical binding]; other site
585535001271	Mg++ binding site [ion binding]; other site
585535001272	motif III; other site
585535001273	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585535001274	nucleotide binding region [chemical binding]; other site
585535001275	ATP-binding site [chemical binding]; other site
585535001276	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
585535001277	SPFH domain / Band 7 family; Region: Band_7; pfam01145
585535001278	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
585535001279	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
585535001280	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585535001281	Walker A/P-loop; other site
585535001282	ATP binding site [chemical binding]; other site
585535001283	Q-loop/lid; other site
585535001284	ABC transporter signature motif; other site
585535001285	Walker B; other site
585535001286	D-loop; other site
585535001287	H-loop/switch region; other site
585535001288	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
585535001289	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585535001290	Walker A/P-loop; other site
585535001291	ATP binding site [chemical binding]; other site
585535001292	Q-loop/lid; other site
585535001293	ABC transporter signature motif; other site
585535001294	Walker B; other site
585535001295	D-loop; other site
585535001296	H-loop/switch region; other site
585535001297	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
585535001298	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535001299	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535001300	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
585535001301	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
585535001302	GDP-binding site [chemical binding]; other site
585535001303	ACT binding site; other site
585535001304	IMP binding site; other site
585535001305	Flagellar FliJ protein; Region: FliJ; pfam02050
585535001306	Uncharacterized conserved protein [Function unknown]; Region: COG3334
585535001307	RIP metalloprotease RseP; Region: TIGR00054
585535001308	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
585535001309	active site
585535001310	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
585535001311	protein binding site [polypeptide binding]; other site
585535001312	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
585535001313	putative substrate binding region [chemical binding]; other site
585535001314	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
585535001315	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
585535001316	generic binding surface II; other site
585535001317	generic binding surface I; other site
585535001318	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
585535001319	DNA methylase; Region: N6_N4_Mtase; pfam01555
585535001320	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
585535001321	Clp amino terminal domain; Region: Clp_N; pfam02861
585535001322	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535001323	Walker A motif; other site
585535001324	ATP binding site [chemical binding]; other site
585535001325	Walker B motif; other site
585535001326	arginine finger; other site
585535001327	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535001328	Walker A motif; other site
585535001329	ATP binding site [chemical binding]; other site
585535001330	Walker B motif; other site
585535001331	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
585535001332	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
585535001333	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
585535001334	Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; Region: PyrC; COG0044
585535001335	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
585535001336	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
585535001337	active site
585535001338	chlorohydrolase; Provisional; Region: PRK08418
585535001339	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_D; cd01312
585535001340	active site
585535001341	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
585535001342	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14339
585535001343	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585535001344	FeS/SAM binding site; other site
585535001345	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
585535001346	putative acyl-acceptor binding pocket; other site
585535001347	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
585535001348	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
585535001349	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
585535001350	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
585535001351	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
585535001352	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
585535001353	putative active site [active]
585535001354	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
585535001355	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
585535001356	putative acyl-acceptor binding pocket; other site
585535001357	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
585535001358	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
585535001359	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3400
585535001360	TrkA-C domain; Region: TrkA_C; pfam02080
585535001361	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
585535001362	active site
585535001363	dimer interface [polypeptide binding]; other site
585535001364	metal binding site [ion binding]; metal-binding site
585535001365	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
585535001366	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585535001367	radical SAM methylthiotransferase, MiaB/RimO family; Region: TIGR00089
585535001368	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
585535001369	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585535001370	FeS/SAM binding site; other site
585535001371	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
585535001372	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535001373	Walker A motif; other site
585535001374	ATP binding site [chemical binding]; other site
585535001375	Walker B motif; other site
585535001376	arginine finger; other site
585535001377	Domain of unknown function (DUF4149); Region: DUF4149; pfam13664
585535001378	diaminopimelate decarboxylase; Region: lysA; TIGR01048
585535001379	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
585535001380	active site
585535001381	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585535001382	substrate binding site [chemical binding]; other site
585535001383	catalytic residues [active]
585535001384	dimer interface [polypeptide binding]; other site
585535001385	Chorismate mutase [Amino acid transport and metabolism]; Region: PheA; COG1605
585535001386	Uncharacterized conserved protein [Function unknown]; Region: COG4866
585535001387	aminodeoxychorismate synthase; Provisional; Region: PRK07508
585535001388	chorismate binding enzyme; Region: Chorismate_bind; cl10555
585535001389	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
585535001390	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
585535001391	substrate-cofactor binding pocket; other site
585535001392	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585535001393	catalytic residue [active]
585535001394	acylamide amidohydrolase; Provisional; Region: amiE; PRK13286
585535001395	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
585535001396	multimer interface [polypeptide binding]; other site
585535001397	active site
585535001398	catalytic triad [active]
585535001399	dimer interface [polypeptide binding]; other site
585535001400	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK08412
585535001401	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
585535001402	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
585535001403	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
585535001404	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
585535001405	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
585535001406	peptide binding site [polypeptide binding]; other site
585535001407	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
585535001408	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585535001409	dimer interface [polypeptide binding]; other site
585535001410	conserved gate region; other site
585535001411	putative PBP binding loops; other site
585535001412	ABC-ATPase subunit interface; other site
585535001413	dipeptide transporter; Provisional; Region: PRK10913
585535001414	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
585535001415	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585535001416	dimer interface [polypeptide binding]; other site
585535001417	conserved gate region; other site
585535001418	putative PBP binding loops; other site
585535001419	ABC-ATPase subunit interface; other site
585535001420	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585535001421	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
585535001422	Walker A/P-loop; other site
585535001423	ATP binding site [chemical binding]; other site
585535001424	Q-loop/lid; other site
585535001425	ABC transporter signature motif; other site
585535001426	Walker B; other site
585535001427	D-loop; other site
585535001428	H-loop/switch region; other site
585535001429	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
585535001430	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
585535001431	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585535001432	Walker A/P-loop; other site
585535001433	ATP binding site [chemical binding]; other site
585535001434	Q-loop/lid; other site
585535001435	ABC transporter signature motif; other site
585535001436	Walker B; other site
585535001437	D-loop; other site
585535001438	H-loop/switch region; other site
585535001439	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
585535001440	GTPase CgtA; Reviewed; Region: obgE; PRK12299
585535001441	GTP1/OBG; Region: GTP1_OBG; pfam01018
585535001442	Obg GTPase; Region: Obg; cd01898
585535001443	G1 box; other site
585535001444	GTP/Mg2+ binding site [chemical binding]; other site
585535001445	Switch I region; other site
585535001446	G2 box; other site
585535001447	G3 box; other site
585535001448	Switch II region; other site
585535001449	G4 box; other site
585535001450	G5 box; other site
585535001451	Alginate lyase; Region: Alginate_lyase; pfam05426
585535001452	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
585535001453	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585535001454	inhibitor-cofactor binding pocket; inhibition site
585535001455	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585535001456	catalytic residue [active]
585535001457	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
585535001458	Predicted amidohydrolase [General function prediction only]; Region: COG0388
585535001459	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
585535001460	active site
585535001461	catalytic triad [active]
585535001462	dimer interface [polypeptide binding]; other site
585535001463	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
585535001464	active site
585535001465	catalytic site [active]
585535001466	Zn binding site [ion binding]; other site
585535001467	tetramer interface [polypeptide binding]; other site
585535001468	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
585535001469	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
585535001470	DNA methylase; Region: N6_N4_Mtase; pfam01555
585535001471	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
585535001472	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
585535001473	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
585535001474	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
585535001475	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585535001476	putative substrate translocation pore; other site
585535001477	heme oxygenase, HugZ family; Region: heme_ox_HugZ; TIGR04109
585535001478	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
585535001479	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
585535001480	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
585535001481	arginyl-tRNA synthetase; Region: argS; TIGR00456
585535001482	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
585535001483	active site
585535001484	HIGH motif; other site
585535001485	KMSK motif region; other site
585535001486	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
585535001487	tRNA binding surface [nucleotide binding]; other site
585535001488	anticodon binding site; other site
585535001489	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
585535001490	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
585535001491	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
585535001492	catalytic site [active]
585535001493	G-X2-G-X-G-K; other site
585535001494	putative inner membrane protein translocase component YidC; Validated; Region: PRK00247
585535001495	nuclease NucT; Provisional; Region: PRK13912
585535001496	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
585535001497	putative active site [active]
585535001498	catalytic site [active]
585535001499	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535001500	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
585535001501	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
585535001502	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
585535001503	ligand binding site; other site
585535001504	tetramer interface; other site
585535001505	Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: spsG; COG3980
585535001506	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
585535001507	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
585535001508	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
585535001509	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
585535001510	NAD synthetase; Provisional; Region: PRK13980
585535001511	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
585535001512	homodimer interface [polypeptide binding]; other site
585535001513	NAD binding pocket [chemical binding]; other site
585535001514	ATP binding pocket [chemical binding]; other site
585535001515	Mg binding site [ion binding]; other site
585535001516	active-site loop [active]
585535001517	ketol-acid reductoisomerase; Provisional; Region: PRK05479
585535001518	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
585535001519	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
585535001520	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
585535001521	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
585535001522	Switch I; other site
585535001523	Switch II; other site
585535001524	cell division topological specificity factor MinE; Region: minE; TIGR01215
585535001525	DNA protecting protein DprA; Region: dprA; TIGR00732
585535001526	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
585535001527	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
585535001528	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
585535001529	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585535001530	Sel1-like repeats; Region: SEL1; smart00671
585535001531	chlorohydrolase; Provisional; Region: PRK07213
585535001532	Predicted membrane protein [Function unknown]; Region: COG3326
585535001533	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
585535001534	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
585535001535	active site
585535001536	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
585535001537	DHH family; Region: DHH; pfam01368
585535001538	DHHA1 domain; Region: DHHA1; pfam02272
585535001539	CTP synthetase; Validated; Region: pyrG; PRK05380
585535001540	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
585535001541	Catalytic site [active]
585535001542	active site
585535001543	UTP binding site [chemical binding]; other site
585535001544	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
585535001545	active site
585535001546	putative oxyanion hole; other site
585535001547	catalytic triad [active]
585535001548	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
585535001549	active site
585535001550	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
585535001551	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
585535001552	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
585535001553	flagellar motor switch protein FliG; Region: fliG; TIGR00207
585535001554	FliG C-terminal domain; Region: FliG_C; pfam01706
585535001555	flagellar assembly protein H; Validated; Region: fliH; PRK06669
585535001556	Flagellar assembly protein FliH; Region: FliH; pfam02108
585535001557	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
585535001558	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
585535001559	TPP-binding site; other site
585535001560	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
585535001561	PYR/PP interface [polypeptide binding]; other site
585535001562	dimer interface [polypeptide binding]; other site
585535001563	TPP binding site [chemical binding]; other site
585535001564	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
585535001565	GTP-binding protein LepA; Provisional; Region: PRK05433
585535001566	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
585535001567	G1 box; other site
585535001568	putative GEF interaction site [polypeptide binding]; other site
585535001569	GTP/Mg2+ binding site [chemical binding]; other site
585535001570	Switch I region; other site
585535001571	G2 box; other site
585535001572	G3 box; other site
585535001573	Switch II region; other site
585535001574	G4 box; other site
585535001575	G5 box; other site
585535001576	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
585535001577	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
585535001578	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
585535001579	Domain of unknown function (DUF3883); Region: DUF3883; pfam13020
585535001580	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
585535001581	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
585535001582	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
585535001583	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585535001584	putative substrate translocation pore; other site
585535001585	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
585535001586	TspO/MBR family; Region: TspO_MBR; cl01379
585535001587	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
585535001588	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
585535001589	Inactivated superfamily I helicase [DNA replication, recombination, and repair]; Region: COG3893
585535001590	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
585535001591	transketolase, bacterial and yeast; Region: tktlase_bact; TIGR00232
585535001592	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
585535001593	TPP-binding site [chemical binding]; other site
585535001594	dimer interface [polypeptide binding]; other site
585535001595	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
585535001596	PYR/PP interface [polypeptide binding]; other site
585535001597	dimer interface [polypeptide binding]; other site
585535001598	TPP binding site [chemical binding]; other site
585535001599	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
585535001600	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
585535001601	riboflavin kinase/FMN adenylyltransferase; Region: ribF; TIGR00083
585535001602	active site
585535001603	Riboflavin kinase; Region: Flavokinase; smart00904
585535001604	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585535001605	hemolysin TlyA family protein; Region: tly; TIGR00478
585535001606	RNA binding surface [nucleotide binding]; other site
585535001607	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585535001608	S-adenosylmethionine binding site [chemical binding]; other site
585535001609	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
585535001610	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
585535001611	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
585535001612	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
585535001613	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
585535001614	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
585535001615	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585535001616	Walker A/P-loop; other site
585535001617	ATP binding site [chemical binding]; other site
585535001618	Q-loop/lid; other site
585535001619	ABC transporter signature motif; other site
585535001620	Walker B; other site
585535001621	D-loop; other site
585535001622	H-loop/switch region; other site
585535001623	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
585535001624	Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes [Defense mechanisms]; Region: COG1787
585535001625	Restriction endonuclease; Region: Mrr_cat; pfam04471
585535001626	Predicted ATPases [General function prediction only]; Region: COG1106
585535001627	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585535001628	Walker A/P-loop; other site
585535001629	ATP binding site [chemical binding]; other site
585535001630	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
585535001631	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cd00596
585535001632	active site
585535001633	Zn binding site [ion binding]; other site
585535001634	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
585535001635	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
585535001636	metal-binding site [ion binding]
585535001637	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
585535001638	metal-binding site [ion binding]
585535001639	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
585535001640	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
585535001641	Soluble P-type ATPase [General function prediction only]; Region: COG4087
585535001642	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
585535001643	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
585535001644	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
585535001645	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535001646	Walker A motif; other site
585535001647	ATP binding site [chemical binding]; other site
585535001648	Walker B motif; other site
585535001649	arginine finger; other site
585535001650	Peptidase family M41; Region: Peptidase_M41; pfam01434
585535001651	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
585535001652	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585535001653	S-adenosylmethionine binding site [chemical binding]; other site
585535001654	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585535001655	Response regulator receiver domain; Region: Response_reg; pfam00072
585535001656	active site
585535001657	phosphorylation site [posttranslational modification]
585535001658	intermolecular recognition site; other site
585535001659	dimerization interface [polypeptide binding]; other site
585535001660	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535001661	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
585535001662	16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Region: gidB; TIGR00138
585535001663	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
585535001664	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
585535001665	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
585535001666	sec-independent translocase; Provisional; Region: PRK04098
585535001667	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
585535001668	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535001669	Walker A motif; other site
585535001670	ATP binding site [chemical binding]; other site
585535001671	Walker B motif; other site
585535001672	arginine finger; other site
585535001673	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
585535001674	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
585535001675	oligomerization interface [polypeptide binding]; other site
585535001676	active site
585535001677	metal binding site [ion binding]; metal-binding site
585535001678	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535001679	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535001680	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
585535001681	septum formation inhibitor; Reviewed; Region: minC; PRK00556
585535001682	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
585535001683	UDP-3-0-acyl N-acetylglucosamine deacetylase; Region: lpxC; TIGR00325
585535001684	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
585535001685	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
585535001686	homoserine kinase; Region: thrB; TIGR00191
585535001687	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
585535001688	Predicted nucleic-acid-binding protein implicated in transcription termination [Transcription]; Region: COG2740
585535001689	putative RNA binding cleft [nucleotide binding]; other site
585535001690	translation initiation factor IF-2; Region: IF-2; TIGR00487
585535001691	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
585535001692	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
585535001693	G1 box; other site
585535001694	putative GEF interaction site [polypeptide binding]; other site
585535001695	GTP/Mg2+ binding site [chemical binding]; other site
585535001696	Switch I region; other site
585535001697	G2 box; other site
585535001698	G3 box; other site
585535001699	Switch II region; other site
585535001700	G4 box; other site
585535001701	G5 box; other site
585535001702	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
585535001703	Translation-initiation factor 2; Region: IF-2; pfam11987
585535001704	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
585535001705	Ribosome-binding factor A; Region: RBFA; cl00542
585535001706	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
585535001707	Sm and related proteins; Region: Sm_like; cl00259
585535001708	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
585535001709	putative oligomer interface [polypeptide binding]; other site
585535001710	putative RNA binding site [nucleotide binding]; other site
585535001711	acetyl-CoA synthetase; Provisional; Region: PRK00174
585535001712	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
585535001713	active site
585535001714	CoA binding site [chemical binding]; other site
585535001715	acyl-activating enzyme (AAE) consensus motif; other site
585535001716	AMP binding site [chemical binding]; other site
585535001717	acetate binding site [chemical binding]; other site
585535001718	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
585535001719	putative active site [active]
585535001720	putative metal binding site [ion binding]; other site
585535001721	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
585535001722	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
585535001723	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585535001724	active site
585535001725	intermolecular recognition site; other site
585535001726	dimerization interface [polypeptide binding]; other site
585535001727	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585535001728	DNA binding site [nucleotide binding]
585535001729	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
585535001730	DHH family; Region: DHH; pfam01368
585535001731	flagellar biosynthesis protein FlhA; Region: FlhA; TIGR01398
585535001732	FHIPEP family; Region: FHIPEP; pfam00771
585535001733	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
585535001734	16S/18S rRNA binding site [nucleotide binding]; other site
585535001735	S13e-L30e interaction site [polypeptide binding]; other site
585535001736	25S rRNA binding site [nucleotide binding]; other site
585535001737	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
585535001738	O-Antigen ligase; Region: Wzy_C; pfam04932
585535001739	Dehydroquinase class II; Region: DHquinase_II; pfam01220
585535001740	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
585535001741	trimer interface [polypeptide binding]; other site
585535001742	active site
585535001743	dimer interface [polypeptide binding]; other site
585535001744	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
585535001745	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
585535001746	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
585535001747	active site
585535001748	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
585535001749	catalytic center binding site [active]
585535001750	ATP binding site [chemical binding]; other site
585535001751	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
585535001752	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
585535001753	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
585535001754	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
585535001755	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
585535001756	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
585535001757	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
585535001758	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
585535001759	DNA binding residues [nucleotide binding]
585535001760	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
585535001761	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
585535001762	flagellar motor switch protein FliY; Validated; Region: PRK08432
585535001763	flagellar motor switch protein FliN; Region: fliN; TIGR02480
585535001764	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
585535001765	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4731
585535001766	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
585535001767	metal binding site 2 [ion binding]; metal-binding site
585535001768	putative DNA binding helix; other site
585535001769	metal binding site 1 [ion binding]; metal-binding site
585535001770	dimer interface [polypeptide binding]; other site
585535001771	structural Zn2+ binding site [ion binding]; other site
585535001772	ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; Region: MGS1; COG2256
585535001773	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535001774	Walker A motif; other site
585535001775	ATP binding site [chemical binding]; other site
585535001776	Walker B motif; other site
585535001777	arginine finger; other site
585535001778	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
585535001779	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
585535001780	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
585535001781	DNA binding residues [nucleotide binding]
585535001782	putative dimer interface [polypeptide binding]; other site
585535001783	chaperone protein DnaJ; Provisional; Region: PRK14299
585535001784	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
585535001785	HSP70 interaction site [polypeptide binding]; other site
585535001786	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
585535001787	substrate binding site [polypeptide binding]; other site
585535001788	dimer interface [polypeptide binding]; other site
585535001789	5'-3' exonuclease; Provisional; Region: PRK14976
585535001790	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
585535001791	putative active site [active]
585535001792	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
585535001793	putative DNA binding site [nucleotide binding]; other site
585535001794	putative metal binding site [ion binding]; other site
585535001795	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
585535001796	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585535001797	active site
585535001798	dimerization interface [polypeptide binding]; other site
585535001799	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
585535001800	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
585535001801	substrate binding site; other site
585535001802	dimer interface; other site
585535001803	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
585535001804	homotrimer interaction site [polypeptide binding]; other site
585535001805	zinc binding site [ion binding]; other site
585535001806	CDP-binding sites; other site
585535001807	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
585535001808	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
585535001809	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585535001810	protein binding site [polypeptide binding]; other site
585535001811	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585535001812	protein binding site [polypeptide binding]; other site
585535001813	S-methylmethionine transporter; Provisional; Region: PRK11387
585535001814	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Region: pgsA; TIGR00560
585535001815	7-alpha-hydroxysteroid dehydrogenase; Provisional; Region: PRK08416
585535001816	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
585535001817	putative NAD(P) binding site [chemical binding]; other site
585535001818	active site
585535001819	dihydrodipicolinate synthase; Region: dapA; TIGR00674
585535001820	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
585535001821	dimer interface [polypeptide binding]; other site
585535001822	active site
585535001823	catalytic residue [active]
585535001824	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
585535001825	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
585535001826	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
585535001827	dihydroorotate dehydrogenase, subfamily 2; Region: pyrD_sub2; TIGR01036
585535001828	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
585535001829	quinone interaction residues [chemical binding]; other site
585535001830	active site
585535001831	catalytic residues [active]
585535001832	FMN binding site [chemical binding]; other site
585535001833	substrate binding site [chemical binding]; other site
585535001834	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
585535001835	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
585535001836	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
585535001837	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
585535001838	putative domain interface [polypeptide binding]; other site
585535001839	putative active site [active]
585535001840	catalytic site [active]
585535001841	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
585535001842	putative active site [active]
585535001843	putative domain interface [polypeptide binding]; other site
585535001844	catalytic site [active]
585535001845	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
585535001846	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
585535001847	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
585535001848	Methyltransferase domain; Region: Methyltransf_26; pfam13659
585535001849	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
585535001850	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
585535001851	ATP binding site [chemical binding]; other site
585535001852	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
585535001853	putative Mg++ binding site [ion binding]; other site
585535001854	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
585535001855	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
585535001856	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
585535001857	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
585535001858	putative metal binding site [ion binding]; other site
585535001859	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
585535001860	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
585535001861	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
585535001862	active site
585535001863	Zn binding site [ion binding]; other site
585535001864	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
585535001865	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
585535001866	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535001867	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
585535001868	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585535001869	Walker A/P-loop; other site
585535001870	ATP binding site [chemical binding]; other site
585535001871	Q-loop/lid; other site
585535001872	ABC transporter signature motif; other site
585535001873	Walker B; other site
585535001874	D-loop; other site
585535001875	H-loop/switch region; other site
585535001876	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
585535001877	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
585535001878	active site
585535001879	HIGH motif; other site
585535001880	nucleotide binding site [chemical binding]; other site
585535001881	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
585535001882	active site
585535001883	KMSKS motif; other site
585535001884	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535001885	Helix-turn-helix domain; Region: HTH_17; pfam12728
585535001886	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
585535001887	Methyltransferase domain; Region: Methyltransf_26; pfam13659
585535001888	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
585535001889	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
585535001890	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
585535001891	ADP-heptose:LPS heptosyl transferase I; Provisional; Region: PRK10964; cl15782
585535001892	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
585535001893	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
585535001894	G1 box; other site
585535001895	putative GEF interaction site [polypeptide binding]; other site
585535001896	GTP/Mg2+ binding site [chemical binding]; other site
585535001897	Switch I region; other site
585535001898	G2 box; other site
585535001899	G3 box; other site
585535001900	Switch II region; other site
585535001901	G4 box; other site
585535001902	G5 box; other site
585535001903	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
585535001904	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
585535001905	Catalytic GIY-YIG domain of coliphage T4 non-specific endonuclease II, type II restriction endonuclease R.Hpy188I, and similar proteins; Region: GIY-YIG_EndoII_Hpy188I_like; cd10436
585535001906	GIY-YIG motif/motif A; other site
585535001907	DNA binding site [nucleotide binding]
585535001908	active site
585535001909	catalytic site [active]
585535001910	metal binding site [ion binding]; metal-binding site
585535001911	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
585535001912	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
585535001913	cofactor binding site; other site
585535001914	DNA binding site [nucleotide binding]
585535001915	substrate interaction site [chemical binding]; other site
585535001916	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
585535001917	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
585535001918	Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153
585535001919	putative heme binding pocket [chemical binding]; other site
585535001920	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
585535001921	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
585535001922	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
585535001923	NPH3 family; Region: NPH3; pfam03000
585535001924	Uncharacterized conserved protein [Function unknown]; Region: COG1432
585535001925	LabA_like proteins; Region: LabA_like; cd06167
585535001926	putative metal binding site [ion binding]; other site
585535001927	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
585535001928	active site
585535001929	putative DNA-binding cleft [nucleotide binding]; other site
585535001930	dimer interface [polypeptide binding]; other site
585535001931	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
585535001932	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
585535001933	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
585535001934	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
585535001935	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
585535001936	tetramer interface [polypeptide binding]; other site
585535001937	heme binding pocket [chemical binding]; other site
585535001938	NADPH binding site [chemical binding]; other site
585535001939	alkylphosphonate utilization operon protein PhnA; Region: phnA; TIGR00686
585535001940	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
585535001941	PhnA protein; Region: PhnA; pfam03831
585535001942	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
585535001943	flagellar hook protein FlgE; Validated; Region: flgE; PRK08425
585535001944	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
585535001945	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
585535001946	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
585535001947	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
585535001948	hydrogenase nickel incorporation protein; Provisional; Region: hypA; PRK00564
585535001949	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
585535001950	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
585535001951	lipid-A-disaccharide synthase; Region: lpxB; TIGR00215
585535001952	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
585535001953	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
585535001954	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
585535001955	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
585535001956	trimer interface [polypeptide binding]; other site
585535001957	active site
585535001958	PQQ-like domain; Region: PQQ_2; pfam13360
585535001959	pantothenate kinase; Reviewed; Region: PRK13333
585535001960	Uncharacterized conserved protein [Function unknown]; Region: COG2836
585535001961	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
585535001962	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585535001963	active site
585535001964	motif I; other site
585535001965	motif II; other site
585535001966	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
585535001967	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
585535001968	NAD(P) binding site [chemical binding]; other site
585535001969	active site
585535001970	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
585535001971	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
585535001972	putative ribose interaction site [chemical binding]; other site
585535001973	putative ADP binding site [chemical binding]; other site
585535001974	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
585535001975	active site
585535001976	nucleotide binding site [chemical binding]; other site
585535001977	HIGH motif; other site
585535001978	KMSKS motif; other site
585535001979	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
585535001980	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
585535001981	dimer interface [polypeptide binding]; other site
585535001982	active site
585535001983	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
585535001984	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
585535001985	active site
585535001986	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
585535001987	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585535001988	Walker A/P-loop; other site
585535001989	ATP binding site [chemical binding]; other site
585535001990	Q-loop/lid; other site
585535001991	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585535001992	ABC transporter; Region: ABC_tran_2; pfam12848
585535001993	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585535001994	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2958
585535001995	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
585535001996	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
585535001997	active site
585535001998	HaeIII restriction endonuclease; Region: RE_HaeIII; pfam09556
585535001999	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
585535002000	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
585535002001	cofactor binding site; other site
585535002002	DNA binding site [nucleotide binding]
585535002003	substrate interaction site [chemical binding]; other site
585535002004	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
585535002005	HsdM N-terminal domain; Region: HsdM_N; pfam12161
585535002006	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585535002007	S-adenosylmethionine binding site [chemical binding]; other site
585535002008	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
585535002009	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
585535002010	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
585535002011	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
585535002012	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
585535002013	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585535002014	ATP binding site [chemical binding]; other site
585535002015	putative Mg++ binding site [ion binding]; other site
585535002016	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
585535002017	substrate binding site [chemical binding]; other site
585535002018	multimerization interface [polypeptide binding]; other site
585535002019	ATP binding site [chemical binding]; other site
585535002020	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
585535002021	dimer interface [polypeptide binding]; other site
585535002022	substrate binding site [chemical binding]; other site
585535002023	ATP binding site [chemical binding]; other site
585535002024	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
585535002025	thiamine phosphate binding site [chemical binding]; other site
585535002026	active site
585535002027	pyrophosphate binding site [ion binding]; other site
585535002028	phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Region: coaBC_dfp; TIGR00521
585535002029	Flavoprotein; Region: Flavoprotein; pfam02441
585535002030	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
585535002031	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
585535002032	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
585535002033	NAD(P) binding site [chemical binding]; other site
585535002034	homodimer interface [polypeptide binding]; other site
585535002035	substrate binding site [chemical binding]; other site
585535002036	active site
585535002037	Long-chain fatty acid transport protein [Lipid metabolism]; Region: FadL; COG2067
585535002038	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
585535002039	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
585535002040	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
585535002041	IHF dimer interface [polypeptide binding]; other site
585535002042	IHF - DNA interface [nucleotide binding]; other site
585535002043	GTP-binding protein Der; Reviewed; Region: PRK00093
585535002044	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
585535002045	G1 box; other site
585535002046	GTP/Mg2+ binding site [chemical binding]; other site
585535002047	Switch I region; other site
585535002048	G2 box; other site
585535002049	Switch II region; other site
585535002050	G3 box; other site
585535002051	G4 box; other site
585535002052	G5 box; other site
585535002053	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
585535002054	G1 box; other site
585535002055	GTP/Mg2+ binding site [chemical binding]; other site
585535002056	Switch I region; other site
585535002057	G2 box; other site
585535002058	G3 box; other site
585535002059	Switch II region; other site
585535002060	G4 box; other site
585535002061	G5 box; other site
585535002062	spermidine synthase; Provisional; Region: speE; PRK00536
585535002063	spermidine synthase; Provisional; Region: PRK00811
585535002064	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
585535002065	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
585535002066	CoA-binding site [chemical binding]; other site
585535002067	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; Region: gatA; TIGR00132
585535002068	indole acetimide hydrolase; Validated; Region: PRK07488
585535002069	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
585535002070	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
585535002071	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
585535002072	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
585535002073	active site
585535002074	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
585535002075	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
585535002076	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
585535002077	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
585535002078	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
585535002079	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585535002080	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585535002081	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
585535002082	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
585535002083	catalytic residues [active]
585535002084	Predicted endonuclease distantly related to archaeal Holliday junction resolvase [DNA replication, recombination, and repair]; Region: COG0792
585535002085	homoserine dehydrogenase; Provisional; Region: PRK06349
585535002086	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
585535002087	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
585535002088	excinuclease ABC, C subunit; Region: uvrC; TIGR00194
585535002089	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
585535002090	GIY-YIG motif/motif A; other site
585535002091	active site
585535002092	catalytic site [active]
585535002093	putative DNA binding site [nucleotide binding]; other site
585535002094	metal binding site [ion binding]; metal-binding site
585535002095	UvrB/uvrC motif; Region: UVR; pfam02151
585535002096	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
585535002097	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
585535002098	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585535002099	Walker A/P-loop; other site
585535002100	ATP binding site [chemical binding]; other site
585535002101	Q-loop/lid; other site
585535002102	ABC transporter signature motif; other site
585535002103	Walker B; other site
585535002104	D-loop; other site
585535002105	H-loop/switch region; other site
585535002106	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585535002107	dimer interface [polypeptide binding]; other site
585535002108	conserved gate region; other site
585535002109	ABC-ATPase subunit interface; other site
585535002110	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
585535002111	flagellar motor protein MotB; Reviewed; Region: motB; PRK08457
585535002112	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585535002113	ligand binding site [chemical binding]; other site
585535002114	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
585535002115	flagellar motor protein MotA; Validated; Region: PRK08456
585535002116	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Region: ThiF; COG0476
585535002117	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
585535002118	ATP binding site [chemical binding]; other site
585535002119	substrate interface [chemical binding]; other site
585535002120	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
585535002121	Uncharacterized conserved protein [Function unknown]; Region: COG1565
585535002122	RNA methyltransferase, RsmD family; Region: TIGR00095
585535002123	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
585535002124	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK08455
585535002125	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
585535002126	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
585535002127	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
585535002128	Predicted methyltransferase regulatory domain; Region: MethyTransf_Reg; pfam10119
585535002129	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09314
585535002130	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: ribB; TIGR00506
585535002131	GTP cyclohydrolase II [Coenzyme metabolism]; Region: RibA; COG0807
585535002132	Domain of unknown function (DUF3943); Region: DUF3943; pfam13084
585535002133	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
585535002134	dimerization interface [polypeptide binding]; other site
585535002135	active site
585535002136	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
585535002137	MoaE homodimer interface [polypeptide binding]; other site
585535002138	MoaD interaction [polypeptide binding]; other site
585535002139	active site residues [active]
585535002140	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
585535002141	MPT binding site; other site
585535002142	trimer interface [polypeptide binding]; other site
585535002143	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
585535002144	trimer interface [polypeptide binding]; other site
585535002145	dimer interface [polypeptide binding]; other site
585535002146	putative active site [active]
585535002147	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
585535002148	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535002149	trigger factor; Provisional; Region: tig; PRK01490
585535002150	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
585535002151	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
585535002152	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
585535002153	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
585535002154	oligomer interface [polypeptide binding]; other site
585535002155	active site residues [active]
585535002156	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
585535002157	active site
585535002158	catalytic residues [active]
585535002159	metal binding site [ion binding]; metal-binding site
585535002160	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
585535002161	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
585535002162	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
585535002163	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
585535002164	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207
585535002165	metal-binding site [ion binding]
585535002166	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
585535002167	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
585535002168	Soluble P-type ATPase [General function prediction only]; Region: COG4087
585535002169	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
585535002170	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
585535002171	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
585535002172	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
585535002173	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
585535002174	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
585535002175	FtsX-like permease family; Region: FtsX; pfam02687
585535002176	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
585535002177	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
585535002178	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585535002179	nucleotide binding region [chemical binding]; other site
585535002180	ATP-binding site [chemical binding]; other site
585535002181	SEC-C motif; Region: SEC-C; pfam02810
585535002182	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
585535002183	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
585535002184	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
585535002185	aconitate hydratase 2; Region: acnB; TIGR00117
585535002186	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
585535002187	substrate binding site [chemical binding]; other site
585535002188	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
585535002189	substrate binding site [chemical binding]; other site
585535002190	ligand binding site [chemical binding]; other site
585535002191	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG1427
585535002192	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
585535002193	putative nucleotide binding site [chemical binding]; other site
585535002194	uridine monophosphate binding site [chemical binding]; other site
585535002195	homohexameric interface [polypeptide binding]; other site
585535002196	DNA-directed RNA polymerase, subunit K/omega [Transcription]; Region: RpoZ; COG1758
585535002197	(p)ppGpp synthetase, RelA/SpoT family; Region: spoT_relA; TIGR00691
585535002198	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
585535002199	Zn2+ binding site [ion binding]; other site
585535002200	Mg2+ binding site [ion binding]; other site
585535002201	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
585535002202	synthetase active site [active]
585535002203	NTP binding site [chemical binding]; other site
585535002204	metal binding site [ion binding]; metal-binding site
585535002205	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
585535002206	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
585535002207	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
585535002208	active site
585535002209	HIGH motif; other site
585535002210	dimer interface [polypeptide binding]; other site
585535002211	KMSKS motif; other site
585535002212	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585535002213	RNA binding surface [nucleotide binding]; other site
585535002214	Nitronate monooxygenase; Region: NMO; pfam03060
585535002215	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
585535002216	FMN binding site [chemical binding]; other site
585535002217	substrate binding site [chemical binding]; other site
585535002218	putative catalytic residue [active]
585535002219	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
585535002220	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
585535002221	active site
585535002222	metal binding site [ion binding]; metal-binding site
585535002223	variable size of poly A (AA/A*) between reads; Unresolved repeat
585535002224	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
585535002225	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
585535002226	signal recognition particle-docking protein FtsY; Region: ftsY; TIGR00064
585535002227	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
585535002228	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
585535002229	phosphodiesterase; Provisional; Region: PRK12704
585535002230	K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; Region: KH-I; cd00105
585535002231	nucleic acid binding region [nucleotide binding]; other site
585535002232	G-X-X-G motif; other site
585535002233	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
585535002234	Zn2+ binding site [ion binding]; other site
585535002235	Mg2+ binding site [ion binding]; other site
585535002236	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
585535002237	putative efflux protein, MATE family; Region: matE; TIGR00797
585535002238	Predicted permease [General function prediction only]; Region: COG2056
585535002239	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
585535002240	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
585535002241	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
585535002242	putative active site; other site
585535002243	catalytic triad [active]
585535002244	putative dimer interface [polypeptide binding]; other site
585535002245	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
585535002246	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
585535002247	putative ATP binding site [chemical binding]; other site
585535002248	putative substrate interface [chemical binding]; other site
585535002249	flagellar biosynthetic protein FliS; Region: fliS; TIGR00208
585535002250	flagellar capping protein; Validated; Region: fliD; PRK08453
585535002251	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
585535002252	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
585535002253	flagellar protein FlaG; Provisional; Region: PRK08452
585535002254	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
585535002255	Peptidase family M23; Region: Peptidase_M23; pfam01551
585535002256	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
585535002257	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
585535002258	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
585535002259	Walker A/P-loop; other site
585535002260	ATP binding site [chemical binding]; other site
585535002261	Q-loop/lid; other site
585535002262	ABC transporter signature motif; other site
585535002263	Walker B; other site
585535002264	D-loop; other site
585535002265	H-loop/switch region; other site
585535002266	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585535002267	S-adenosylmethionine binding site [chemical binding]; other site
585535002268	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
585535002269	Interdomain contacts; other site
585535002270	Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401
585535002271	Cytokine receptor motif; other site
585535002272	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
585535002273	Interdomain contacts; other site
585535002274	Cytokine receptor motif; other site
585535002275	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
585535002276	Interdomain contacts; other site
585535002277	Cytokine receptor motif; other site
585535002278	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
585535002279	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
585535002280	active site
585535002281	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
585535002282	G1 box; other site
585535002283	GTP/Mg2+ binding site [chemical binding]; other site
585535002284	Predicted GTPase [General function prediction only]; Region: COG3596
585535002285	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
585535002286	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
585535002287	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
585535002288	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585535002289	active site
585535002290	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
585535002291	nucleotide binding site/active site [active]
585535002292	HIT family signature motif; other site
585535002293	catalytic residue [active]
585535002294	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
585535002295	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585535002296	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
585535002297	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
585535002298	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
585535002299	ATP-grasp domain; Region: ATP-grasp_4; cl17255
585535002300	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
585535002301	tetramer interfaces [polypeptide binding]; other site
585535002302	binuclear metal-binding site [ion binding]; other site
585535002303	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
585535002304	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585535002305	catalytic residue [active]
585535002306	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236
585535002307	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585535002308	active site
585535002309	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
585535002310	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
585535002311	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585535002312	FeS/SAM binding site; other site
585535002313	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
585535002314	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14337
585535002315	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
585535002316	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
585535002317	Ligand Binding Site [chemical binding]; other site
585535002318	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
585535002319	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
585535002320	FMN binding site [chemical binding]; other site
585535002321	active site
585535002322	catalytic residues [active]
585535002323	substrate binding site [chemical binding]; other site
585535002324	variable size of poly T (TT/T*) between reads; Unresolved repeat
585535002325	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535002326	anaerobic c4-dicarboxylate membrane transporter family protein; Region: Dcu; TIGR00770
585535002327	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
585535002328	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
585535002329	active site
585535002330	homodimer interface [polypeptide binding]; other site
585535002331	homotetramer interface [polypeptide binding]; other site
585535002332	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
585535002333	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
585535002334	Lysine efflux permease [General function prediction only]; Region: COG1279
585535002335	DNA polymerase III subunits gamma and tau; Validated; Region: PRK08451
585535002336	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535002337	Walker A motif; other site
585535002338	ATP binding site [chemical binding]; other site
585535002339	Walker B motif; other site
585535002340	arginine finger; other site
585535002341	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
585535002342	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
585535002343	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
585535002344	Walker A/P-loop; other site
585535002345	ATP binding site [chemical binding]; other site
585535002346	Q-loop/lid; other site
585535002347	ABC transporter signature motif; other site
585535002348	Walker B; other site
585535002349	D-loop; other site
585535002350	H-loop/switch region; other site
585535002351	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
585535002352	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
585535002353	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
585535002354	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
585535002355	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535002356	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
585535002357	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
585535002358	Uncharacterized conserved protein [Function unknown]; Region: COG1912
585535002359	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
585535002360	MraW methylase family; Region: Methyltransf_5; cl17771
585535002361	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535002362	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
585535002363	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
585535002364	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
585535002365	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
585535002366	Response regulator receiver domain; Region: Response_reg; pfam00072
585535002367	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585535002368	active site
585535002369	phosphorylation site [posttranslational modification]
585535002370	intermolecular recognition site; other site
585535002371	dimerization interface [polypeptide binding]; other site
585535002372	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535002373	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
585535002374	Walker A motif; other site
585535002375	ATP binding site [chemical binding]; other site
585535002376	Walker B motif; other site
585535002377	arginine finger; other site
585535002378	DNA gyrase subunit A; Validated; Region: PRK05560
585535002379	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
585535002380	CAP-like domain; other site
585535002381	active site
585535002382	primary dimer interface [polypeptide binding]; other site
585535002383	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585535002384	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585535002385	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585535002386	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585535002387	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585535002388	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585535002389	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
585535002390	Acetone carboxylase, gamma subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcxC; COG4647
585535002391	Acetone carboxylase gamma subunit; Region: Acetone_carb_G; pfam08882
585535002392	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
585535002393	Hydantoinase B/oxoprolinase; Region: Hydantoinase_B; pfam02538
585535002394	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
585535002395	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
585535002396	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
585535002397	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
585535002398	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
585535002399	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
585535002400	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
585535002401	putative acyltransferase; Provisional; Region: PRK05790
585535002402	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
585535002403	dimer interface [polypeptide binding]; other site
585535002404	active site
585535002405	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
585535002406	active site
585535002407	catalytic site [active]
585535002408	substrate binding site [chemical binding]; other site
585535002409	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108
585535002410	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
585535002411	ferrous iron transporter FeoB; Region: feoB; TIGR00437
585535002412	G1 box; other site
585535002413	GTP/Mg2+ binding site [chemical binding]; other site
585535002414	Switch I region; other site
585535002415	G2 box; other site
585535002416	G3 box; other site
585535002417	Switch II region; other site
585535002418	G4 box; other site
585535002419	G5 box; other site
585535002420	Nucleoside recognition; Region: Gate; pfam07670
585535002421	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
585535002422	Nucleoside recognition; Region: Gate; pfam07670
585535002423	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
585535002424	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585535002425	N-terminal plug; other site
585535002426	ligand-binding site [chemical binding]; other site
585535002427	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
585535002428	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14359
585535002429	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
585535002430	Substrate binding site; other site
585535002431	Mg++ binding site; other site
585535002432	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
585535002433	active site
585535002434	substrate binding site [chemical binding]; other site
585535002435	CoA binding site [chemical binding]; other site
585535002436	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08447
585535002437	ATP cone domain; Region: ATP-cone; pfam03477
585535002438	Class I ribonucleotide reductase; Region: RNR_I; cd01679
585535002439	active site
585535002440	dimer interface [polypeptide binding]; other site
585535002441	catalytic residues [active]
585535002442	effector binding site; other site
585535002443	R2 peptide binding site; other site
585535002444	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
585535002445	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585535002446	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
585535002447	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
585535002448	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
585535002449	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
585535002450	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
585535002451	DNA binding site [nucleotide binding]
585535002452	active site
585535002453	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
585535002454	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
585535002455	active site
585535002456	DNA binding site [nucleotide binding]
585535002457	Int/Topo IB signature motif; other site
585535002458	aspartate aminotransferase; Provisional; Region: PRK05764
585535002459	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585535002460	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585535002461	homodimer interface [polypeptide binding]; other site
585535002462	catalytic residue [active]
585535002463	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535002464	Predicted helicase [General function prediction only]; Region: COG4889
585535002465	Restriction endonuclease; Region: Mrr_cat_2; pfam13156
585535002466	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585535002467	ATP binding site [chemical binding]; other site
585535002468	putative Mg++ binding site [ion binding]; other site
585535002469	nucleotide binding region [chemical binding]; other site
585535002470	Helicase conserved C-terminal domain; Region: Helicase_C; pfam00271
585535002471	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
585535002472	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585535002473	Cysteine-rich domain; Region: CCG; pfam02754
585535002474	Cysteine-rich domain; Region: CCG; pfam02754
585535002475	oxygen-independent coproporphyrinogen III oxidase; Region: hemN; TIGR00538
585535002476	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585535002477	FeS/SAM binding site; other site
585535002478	HemN C-terminal domain; Region: HemN_C; pfam06969
585535002479	Protein of unknown function (DUF2603); Region: DUF2603; pfam10788
585535002480	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
585535002481	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
585535002482	Tetramer interface [polypeptide binding]; other site
585535002483	active site
585535002484	FMN-binding site [chemical binding]; other site
585535002485	ribonuclease III; Reviewed; Region: rnc; PRK00102
585535002486	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
585535002487	dimerization interface [polypeptide binding]; other site
585535002488	active site
585535002489	metal binding site [ion binding]; metal-binding site
585535002490	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
585535002491	dsRNA binding site [nucleotide binding]; other site
585535002492	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
585535002493	RNA/DNA hybrid binding site [nucleotide binding]; other site
585535002494	active site
585535002495	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
585535002496	Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module [General function prediction only]; Region: COG1439
585535002497	SurA N-terminal domain; Region: SurA_N; pfam09312
585535002498	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
585535002499	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
585535002500	GatB domain; Region: GatB_Yqey; smart00845
585535002501	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
585535002502	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
585535002503	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
585535002504	hypothetical protein; Provisional; Region: PRK08445
585535002505	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585535002506	FeS/SAM binding site; other site
585535002507	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
585535002508	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585535002509	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585535002510	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585535002511	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585535002512	Surface antigen; Region: Bac_surface_Ag; pfam01103
585535002513	hypothetical protein; Provisional; Region: PRK08444
585535002514	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585535002515	FeS/SAM binding site; other site
585535002516	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
585535002517	Ferritin-like domain; Region: Ferritin; pfam00210
585535002518	ferroxidase diiron center [ion binding]; other site
585535002519	phosphoserine phosphatase SerB; Region: serB; TIGR00338
585535002520	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585535002521	motif II; other site
585535002522	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
585535002523	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
585535002524	ligand binding site [chemical binding]; other site
585535002525	active site
585535002526	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
585535002527	Aspartase; Region: Aspartase; cd01357
585535002528	active sites [active]
585535002529	tetramer interface [polypeptide binding]; other site
585535002530	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
585535002531	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
585535002532	hinge; other site
585535002533	active site
585535002534	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
585535002535	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
585535002536	active site
585535002537	tetramer interface; other site
585535002538	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
585535002539	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585535002540	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585535002541	catalytic residue [active]
585535002542	YGGT family; Region: YGGT; pfam02325
585535002543	glutamylglutaminyl-tRNA synthetase; Provisional; Region: PRK12410
585535002544	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
585535002545	active site
585535002546	HIGH motif; other site
585535002547	nucleotide binding site [chemical binding]; other site
585535002548	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
585535002549	active site
585535002550	KMSKS motif; other site
585535002551	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
585535002552	dimer interface [polypeptide binding]; other site
585535002553	FMN binding site [chemical binding]; other site
585535002554	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
585535002555	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
585535002556	active site
585535002557	NTP binding site [chemical binding]; other site
585535002558	metal binding triad [ion binding]; metal-binding site
585535002559	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
585535002560	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
585535002561	Ligand Binding Site [chemical binding]; other site
585535002562	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535002563	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK06466
585535002564	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
585535002565	nickel binding site [ion binding]; other site
585535002566	putative substrate-binding site; other site
585535002567	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
585535002568	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
585535002569	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
585535002570	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
585535002571	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
585535002572	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
585535002573	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585535002574	Sel1-like repeats; Region: SEL1; smart00671
585535002575	Sel1-like repeats; Region: SEL1; smart00671
585535002576	Sel1 repeat; Region: Sel1; cl02723
585535002577	Sel1-like repeats; Region: SEL1; smart00671
585535002578	Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Region: DapD; COG2171
585535002579	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
585535002580	putative trimer interface [polypeptide binding]; other site
585535002581	putative CoA binding site [chemical binding]; other site
585535002582	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
585535002583	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
585535002584	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
585535002585	hypothetical protein; Provisional; Region: PRK05839
585535002586	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585535002587	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585535002588	homodimer interface [polypeptide binding]; other site
585535002589	catalytic residue [active]
585535002590	UDP-N-acetylmuramate--alanine ligase; Region: murC; TIGR01082
585535002591	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
585535002592	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585535002593	MutS2 family protein; Region: mutS2; TIGR01069
585535002594	ATPase domain of DNA mismatch repair MUTS family; Region: MUTSac; smart00534
585535002595	Walker A/P-loop; other site
585535002596	ATP binding site [chemical binding]; other site
585535002597	Q-loop/lid; other site
585535002598	ABC transporter signature motif; other site
585535002599	Walker B; other site
585535002600	D-loop; other site
585535002601	H-loop/switch region; other site
585535002602	Smr domain; Region: Smr; pfam01713
585535002603	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
585535002604	dimer interface [polypeptide binding]; other site
585535002605	substrate binding site [chemical binding]; other site
585535002606	metal binding sites [ion binding]; metal-binding site
585535002607	variable size of tandem repeat between reads; Unresolved repeat
585535002608	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
585535002609	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
585535002610	adenylate kinase; Reviewed; Region: adk; PRK00279
585535002611	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
585535002612	AMP-binding site [chemical binding]; other site
585535002613	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
585535002614	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
585535002615	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
585535002616	dimer interface [polypeptide binding]; other site
585535002617	anticodon binding site; other site
585535002618	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
585535002619	homodimer interface [polypeptide binding]; other site
585535002620	motif 1; other site
585535002621	active site
585535002622	motif 2; other site
585535002623	GAD domain; Region: GAD; pfam02938
585535002624	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
585535002625	active site
585535002626	motif 3; other site
585535002627	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
585535002628	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
585535002629	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585535002630	active site
585535002631	phosphorylation site [posttranslational modification]
585535002632	intermolecular recognition site; other site
585535002633	dimerization interface [polypeptide binding]; other site
585535002634	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
585535002635	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
585535002636	nucleotide binding pocket [chemical binding]; other site
585535002637	K-X-D-G motif; other site
585535002638	catalytic site [active]
585535002639	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
585535002640	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
585535002641	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
585535002642	Dimer interface [polypeptide binding]; other site
585535002643	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
585535002644	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
585535002645	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
585535002646	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
585535002647	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
585535002648	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
585535002649	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
585535002650	Autotransporter beta-domain; Region: Autotransporter; pfam03797
585535002651	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535002652	AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873
585535002653	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585535002654	HlyD family secretion protein; Region: HlyD_3; pfam13437
585535002655	Outer membrane efflux protein; Region: OEP; pfam02321
585535002656	Outer membrane efflux protein; Region: OEP; pfam02321
585535002657	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
585535002658	substrate binding site [chemical binding]; other site
585535002659	active site
585535002660	3-methyladenine DNA glycosylase; Provisional; Region: PRK13913
585535002661	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
585535002662	minor groove reading motif; other site
585535002663	helix-hairpin-helix signature motif; other site
585535002664	active site
585535002665	flagellin A; Reviewed; Region: PRK12584
585535002666	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
585535002667	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
585535002668	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
585535002669	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
585535002670	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585535002671	ABC transporter; Region: ABC_tran; pfam00005
585535002672	Q-loop/lid; other site
585535002673	ABC transporter signature motif; other site
585535002674	Walker B; other site
585535002675	D-loop; other site
585535002676	H-loop/switch region; other site
585535002677	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
585535002678	dimer interface [polypeptide binding]; other site
585535002679	putative CheW interface [polypeptide binding]; other site
585535002680	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
585535002681	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
585535002682	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
585535002683	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585535002684	catalytic residue [active]
585535002685	Transglycosylase; Region: Transgly; pfam00912
585535002686	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
585535002687	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
585535002688	tumor necrosis factor alpha-inducing protein; Reviewed; Region: PRK12303
585535002689	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
585535002690	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
585535002691	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Region: HAD-SF-IA-v1; TIGR01549
585535002692	2-oxoglutarate-acceptor oxidoreductase subunit OorC; Reviewed; Region: oorC; PRK08441
585535002693	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
585535002694	2-oxoglutarate-acceptor oxidoreductase subunit OorB; Reviewed; Region: oorB; PRK09628
585535002695	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
585535002696	TPP-binding site [chemical binding]; other site
585535002697	2-oxoglutarate-acceptor oxidoreductase subunit OorA; Reviewed; Region: oorA; PRK09627
585535002698	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
585535002699	dimer interface [polypeptide binding]; other site
585535002700	PYR/PP interface [polypeptide binding]; other site
585535002701	TPP binding site [chemical binding]; other site
585535002702	substrate binding site [chemical binding]; other site
585535002703	2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed; Region: oorD; PRK09626
585535002704	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
585535002705	YceG-like family; Region: YceG; pfam02618
585535002706	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
585535002707	dimerization interface [polypeptide binding]; other site
585535002708	Protein of unknown function; Region: DUF3971; pfam13116
585535002709	AsmA-like C-terminal region; Region: AsmA_1; pfam13109
585535002710	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
585535002711	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
585535002712	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
585535002713	minor groove reading motif; other site
585535002714	helix-hairpin-helix signature motif; other site
585535002715	substrate binding pocket [chemical binding]; other site
585535002716	active site
585535002717	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
585535002718	flagellar motor switch protein; Validated; Region: PRK08433
585535002719	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
585535002720	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
585535002721	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
585535002722	active site
585535002723	substrate binding pocket [chemical binding]; other site
585535002724	dimer interface [polypeptide binding]; other site
585535002725	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
585535002726	BNR repeat-like domain; Region: BNR_2; pfam13088
585535002727	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
585535002728	Sulfatase; Region: Sulfatase; pfam00884
585535002729	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14191
585535002730	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
585535002731	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
585535002732	homodimer interface [polypeptide binding]; other site
585535002733	NADP binding site [chemical binding]; other site
585535002734	substrate binding site [chemical binding]; other site
585535002735	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
585535002736	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
585535002737	Catalytic site [active]
585535002738	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
585535002739	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
585535002740	Peptidase family M50; Region: Peptidase_M50; pfam02163
585535002741	active site
585535002742	putative substrate binding region [chemical binding]; other site
585535002743	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
585535002744	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
585535002745	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585535002746	active site
585535002747	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
585535002748	multifunctional aminopeptidase A; Provisional; Region: PRK00913
585535002749	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
585535002750	interface (dimer of trimers) [polypeptide binding]; other site
585535002751	Substrate-binding/catalytic site; other site
585535002752	Zn-binding sites [ion binding]; other site
585535002753	GTP-binding protein YchF; Reviewed; Region: PRK09601
585535002754	YchF GTPase; Region: YchF; cd01900
585535002755	G1 box; other site
585535002756	GTP/Mg2+ binding site [chemical binding]; other site
585535002757	Switch I region; other site
585535002758	G2 box; other site
585535002759	Switch II region; other site
585535002760	G3 box; other site
585535002761	G4 box; other site
585535002762	G5 box; other site
585535002763	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
585535002764	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585535002765	FeS/SAM binding site; other site
585535002766	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
585535002767	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
585535002768	Domain of unknown function DUF20; Region: UPF0118; pfam01594
585535002769	diaminopimelate epimerase; Region: DapF; TIGR00652
585535002770	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
585535002771	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
585535002772	Predicted membrane protein [Function unknown]; Region: COG3059
585535002773	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
585535002774	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
585535002775	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
585535002776	NAD(P) binding site [chemical binding]; other site
585535002777	active site
585535002778	acyl carrier protein; Provisional; Region: acpP; PRK00982
585535002779	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK08439
585535002780	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
585535002781	dimer interface [polypeptide binding]; other site
585535002782	active site
585535002783	acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Region: accA; TIGR00513
585535002784	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
585535002785	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
585535002786	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
585535002787	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
585535002788	Predicted methyltransferases [General function prediction only]; Region: COG0313
585535002789	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
585535002790	putative SAM binding site [chemical binding]; other site
585535002791	putative homodimer interface [polypeptide binding]; other site
585535002792	Ribosomal protein L31; Region: Ribosomal_L31; pfam01197
585535002793	transcription termination factor Rho; Provisional; Region: rho; PRK09376
585535002794	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
585535002795	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
585535002796	RNA binding site [nucleotide binding]; other site
585535002797	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
585535002798	multimer interface [polypeptide binding]; other site
585535002799	Walker A motif; other site
585535002800	ATP binding site [chemical binding]; other site
585535002801	Walker B motif; other site
585535002802	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
585535002803	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
585535002804	CagA exotoxin; Region: CagA; pfam03507
585535002805	CagA exotoxin; Region: CagA; pfam03507
585535002806	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
585535002807	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
585535002808	prolyl-tRNA synthetase; Provisional; Region: PRK08661
585535002809	Cag pathogenicity island protein Cag12; Region: Cag12; pfam13117
585535002810	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
585535002811	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
585535002812	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
585535002813	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
585535002814	VirB7 interaction site; other site
585535002815	DC-EC Repeat; Region: CagY_M; pfam07337
585535002816	DC-EC Repeat; Region: CagY_M; pfam07337
585535002817	DC-EC Repeat; Region: CagY_M; pfam07337
585535002818	DC-EC Repeat; Region: CagY_M; pfam07337
585535002819	DC-EC Repeat; Region: CagY_M; pfam07337
585535002820	DC-EC Repeat; Region: CagY_M; pfam07337
585535002821	DC-EC Repeat; Region: CagY_M; pfam07337
585535002822	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
585535002823	unresolved imperfect repeat.; Unresolved repeat
585535002824	CagZ; Region: CagZ; pfam09053
585535002825	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
585535002826	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
585535002827	ATP binding site [chemical binding]; other site
585535002828	Walker A motif; other site
585535002829	hexamer interface [polypeptide binding]; other site
585535002830	Walker B motif; other site
585535002831	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
585535002832	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
585535002833	Walker A motif; other site
585535002834	ATP binding site [chemical binding]; other site
585535002835	Walker B motif; other site
585535002836	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
585535002837	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585535002838	Sel1 repeat; Region: Sel1; cl02723
585535002839	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
585535002840	GTPase [General function prediction only]; Region: Era; COG1159
585535002841	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
585535002842	G1 box; other site
585535002843	GTP/Mg2+ binding site [chemical binding]; other site
585535002844	Switch I region; other site
585535002845	G2 box; other site
585535002846	Switch II region; other site
585535002847	G3 box; other site
585535002848	G4 box; other site
585535002849	G5 box; other site
585535002850	KH domain; Region: KH_2; pfam07650
585535002851	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
585535002852	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535002853	Walker A motif; other site
585535002854	ATP binding site [chemical binding]; other site
585535002855	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
585535002856	Walker B motif; other site
585535002857	arginine finger; other site
585535002858	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
585535002859	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
585535002860	active site
585535002861	HslU subunit interaction site [polypeptide binding]; other site
585535002862	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
585535002863	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
585535002864	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
585535002865	Uncharacterized conserved protein [Function unknown]; Region: COG1479
585535002866	Protein of unknown function DUF262; Region: DUF262; pfam03235
585535002867	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
585535002868	Uncharacterized conserved protein [Function unknown]; Region: COG3586
585535002869	glutamine synthetase, type I; Region: GlnA; TIGR00653
585535002870	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
585535002871	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
585535002872	dihydrodipicolinate reductase; Region: dapB; TIGR00036
585535002873	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
585535002874	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
585535002875	FAD binding domain; Region: FAD_binding_4; pfam01565
585535002876	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
585535002877	Protein-interacting Bro1-like domain of mammalian Alix and related domains; Region: BRO1_Alix_like; cl14649
585535002878	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
585535002879	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
585535002880	dimer interface [polypeptide binding]; other site
585535002881	ADP-ribose binding site [chemical binding]; other site
585535002882	active site
585535002883	nudix motif; other site
585535002884	metal binding site [ion binding]; metal-binding site
585535002885	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
585535002886	Peptidase family M23; Region: Peptidase_M23; pfam01551
585535002887	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
585535002888	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585535002889	Mg2+ binding site [ion binding]; other site
585535002890	G-X-G motif; other site
585535002891	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
585535002892	anchoring element; other site
585535002893	dimer interface [polypeptide binding]; other site
585535002894	ATP binding site [chemical binding]; other site
585535002895	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
585535002896	active site
585535002897	putative metal-binding site [ion binding]; other site
585535002898	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
585535002899	DNA polymerase III, beta subunit; Region: dnan; TIGR00663
585535002900	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
585535002901	putative DNA binding surface [nucleotide binding]; other site
585535002902	dimer interface [polypeptide binding]; other site
585535002903	beta-clamp/translesion DNA polymerase binding surface; other site
585535002904	beta-clamp/clamp loader binding surface; other site
585535002905	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
585535002906	dimerization interface [polypeptide binding]; other site
585535002907	substrate binding site [chemical binding]; other site
585535002908	active site
585535002909	calcium binding site [ion binding]; other site
585535002910	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
585535002911	Na2 binding site [ion binding]; other site
585535002912	putative substrate binding site 1 [chemical binding]; other site
585535002913	Na binding site 1 [ion binding]; other site
585535002914	putative substrate binding site 2 [chemical binding]; other site
585535002915	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
585535002916	Na2 binding site [ion binding]; other site
585535002917	putative substrate binding site 1 [chemical binding]; other site
585535002918	Na binding site 1 [ion binding]; other site
585535002919	putative substrate binding site 2 [chemical binding]; other site
585535002920	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
585535002921	active site
585535002922	Protein of unknown function (DUF493); Region: DUF493; pfam04359
585535002923	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03815
585535002924	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585535002925	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585535002926	phospho-N-acetylmuramoyl-pentapeptide-transferase; Region: mraY; TIGR00445
585535002927	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
585535002928	Mg++ binding site [ion binding]; other site
585535002929	putative catalytic motif [active]
585535002930	putative substrate binding site [chemical binding]; other site
585535002931	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
585535002932	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
585535002933	Cation transport protein; Region: TrkH; cl17365
585535002934	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
585535002935	TrkA-N domain; Region: TrkA_N; pfam02254
585535002936	TrkA-C domain; Region: TrkA_C; pfam02080
585535002937	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
585535002938	Holliday junction DNA helicase, RuvA subunit; Region: ruvA; TIGR00084
585535002939	RuvA N terminal domain; Region: RuvA_N; pfam01330
585535002940	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
585535002941	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
585535002942	MviN-like protein; Region: MVIN; pfam03023
585535002943	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
585535002944	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
585535002945	active site
585535002946	HIGH motif; other site
585535002947	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
585535002948	KMSKS motif; other site
585535002949	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
585535002950	tRNA binding surface [nucleotide binding]; other site
585535002951	anticodon binding site; other site
585535002952	Vacuolating cyotoxin; Region: VacA; pfam02691
585535002953	Autotransporter beta-domain; Region: Autotransporter; pfam03797
585535002954	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
585535002955	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
585535002956	Walker A/P-loop; other site
585535002957	ATP binding site [chemical binding]; other site
585535002958	Q-loop/lid; other site
585535002959	ABC transporter signature motif; other site
585535002960	Walker B; other site
585535002961	D-loop; other site
585535002962	H-loop/switch region; other site
585535002963	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585535002964	ABC-ATPase subunit  interface; other site
585535002965	dimer interface [polypeptide binding]; other site
585535002966	putative PBP binding regions; other site
585535002967	short chain dehydrogenase; Validated; Region: PRK06182
585535002968	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
585535002969	NADP binding site [chemical binding]; other site
585535002970	active site
585535002971	steroid binding site; other site
585535002972	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
585535002973	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
585535002974	variable size of poly A (10A/9A) between reads; Unresolved repeat
585535002975	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535002976	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
585535002977	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
585535002978	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypC; COG0298
585535002979	hydrogenase accessory protein HypB; Region: hypB; TIGR00073
585535002980	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
585535002981	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
585535002982	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
585535002983	propionate/acetate kinase; Provisional; Region: PRK12379
585535002984	BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; Region: Pta; COG0857
585535002985	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
585535002986	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
585535002987	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK05842
585535002988	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
585535002989	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
585535002990	flagellar hook protein FlgE; Validated; Region: flgE; PRK05841
585535002991	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
585535002992	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
585535002993	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585535002994	S-adenosylmethionine binding site [chemical binding]; other site
585535002995	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
585535002996	Part of AAA domain; Region: AAA_19; pfam13245
585535002997	Family description; Region: UvrD_C_2; pfam13538
585535002998	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535002999	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535003000	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
585535003001	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
585535003002	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
585535003003	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
585535003004	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
585535003005	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
585535003006	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
585535003007	ATP-grasp domain; Region: ATP-grasp_4; cl17255
585535003008	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
585535003009	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
585535003010	ATP-grasp domain; Region: ATP-grasp_4; cl17255
585535003011	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
585535003012	IMP binding site; other site
585535003013	dimer interface [polypeptide binding]; other site
585535003014	interdomain contacts; other site
585535003015	partial ornithine binding site; other site
585535003016	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
585535003017	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
585535003018	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
585535003019	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
585535003020	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
585535003021	Mechanosensitive ion channel porin domain; Region: MscS_porin; pfam12795
585535003022	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
585535003023	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
585535003024	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
585535003025	Autotransporter beta-domain; Region: Autotransporter; pfam03797
585535003026	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535003027	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
585535003028	active site 1 [active]
585535003029	dimer interface [polypeptide binding]; other site
585535003030	hexamer interface [polypeptide binding]; other site
585535003031	active site 2 [active]
585535003032	recombination protein RecR; Region: recR; TIGR00615
585535003033	RecR protein; Region: RecR; pfam02132
585535003034	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
585535003035	putative active site [active]
585535003036	putative metal-binding site [ion binding]; other site
585535003037	tetramer interface [polypeptide binding]; other site
585535003038	tRNA pseudouridine synthase, TruD family; Region: tRNA_TruD_broad; TIGR00094
585535003039	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
585535003040	Permutation of conserved domain; other site
585535003041	active site
585535003042	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
585535003043	heat shock protein HtpX; Provisional; Region: PRK02870
585535003044	GTP cyclohydrolase I; Region: folE; TIGR00063
585535003045	GTP cyclohydrolase I; Provisional; Region: PLN03044
585535003046	active site
585535003047	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
585535003048	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
585535003049	substrate binding pocket [chemical binding]; other site
585535003050	chain length determination region; other site
585535003051	substrate-Mg2+ binding site; other site
585535003052	catalytic residues [active]
585535003053	aspartate-rich region 1; other site
585535003054	active site lid residues [active]
585535003055	aspartate-rich region 2; other site
585535003056	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
585535003057	6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Region: COG0720
585535003058	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
585535003059	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
585535003060	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
585535003061	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585535003062	Coenzyme A binding pocket [chemical binding]; other site
585535003063	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
585535003064	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535003065	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585535003066	metabolite-proton symporter; Region: 2A0106; TIGR00883
585535003067	putative substrate translocation pore; other site
585535003068	Uncharacterized conserved protein [Function unknown]; Region: COG1479
585535003069	Protein of unknown function DUF262; Region: DUF262; pfam03235
585535003070	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
585535003071	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585535003072	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585535003073	dimer interface [polypeptide binding]; other site
585535003074	conserved gate region; other site
585535003075	putative PBP binding loops; other site
585535003076	ABC-ATPase subunit interface; other site
585535003077	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
585535003078	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585535003079	substrate binding pocket [chemical binding]; other site
585535003080	membrane-bound complex binding site; other site
585535003081	hinge residues; other site
585535003082	alanine racemase; Region: alr; TIGR00492
585535003083	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
585535003084	active site
585535003085	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585535003086	dimer interface [polypeptide binding]; other site
585535003087	substrate binding site [chemical binding]; other site
585535003088	catalytic residues [active]
585535003089	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
585535003090	amino acid carrier protein; Region: agcS; TIGR00835
585535003091	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
585535003092	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
585535003093	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
585535003094	homotrimer interaction site [polypeptide binding]; other site
585535003095	putative active site [active]
585535003096	TRL-like protein family; Region: TRL; pfam13146
585535003097	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
585535003098	Uncharacterized conserved protein [Function unknown]; Region: COG1576
585535003099	acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Region: accD; TIGR00515
585535003100	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
585535003101	putative recombination protein RecO; Provisional; Region: PRK13908
585535003102	competence/damage-inducible protein CinA C-terminal domain; Region: cinA_cterm; TIGR00199
585535003103	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
585535003104	dimer interface [polypeptide binding]; other site
585535003105	FMN binding site [chemical binding]; other site
585535003106	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
585535003107	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
585535003108	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
585535003109	active site
585535003110	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
585535003111	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
585535003112	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
585535003113	Putative zinc ribbon domain; Region: DUF164; pfam02591
585535003114	dinuclear metal center protein, YbgI/SA1388 family; Region: YbgI_SA1388; TIGR00486
585535003115	Uncharacterized conserved protein [Function unknown]; Region: COG0327
585535003116	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
585535003117	dimer interface [polypeptide binding]; other site
585535003118	motif 1; other site
585535003119	active site
585535003120	motif 2; other site
585535003121	motif 3; other site
585535003122	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
585535003123	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
585535003124	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
585535003125	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
585535003126	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
585535003127	Outer membrane efflux protein; Region: OEP; pfam02321
585535003128	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
585535003129	phosphoglyceromutase; Provisional; Region: PRK05434
585535003130	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
585535003131	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; Region: gatC; TIGR00135
585535003132	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
585535003133	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585535003134	inhibitor-cofactor binding pocket; inhibition site
585535003135	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585535003136	catalytic residue [active]
585535003137	SurA N-terminal domain; Region: SurA_N_3; cl07813
585535003138	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
585535003139	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
585535003140	cell division protein FtsA; Region: ftsA; TIGR01174
585535003141	Cell division protein FtsA; Region: FtsA; smart00842
585535003142	Cell division protein FtsA; Region: FtsA; pfam14450
585535003143	cell division protein FtsZ; Validated; Region: PRK09330
585535003144	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
585535003145	nucleotide binding site [chemical binding]; other site
585535003146	SulA interaction site; other site
585535003147	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585535003148	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
585535003149	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
585535003150	active site
585535003151	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585535003152	catalytic residues [active]
585535003153	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
585535003154	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
585535003155	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
585535003156	putative ADP-binding pocket [chemical binding]; other site
585535003157	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
585535003158	active site 2 [active]
585535003159	active site 1 [active]
585535003160	Methyltransferase domain; Region: Methyltransf_23; pfam13489
585535003161	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585535003162	S-adenosylmethionine binding site [chemical binding]; other site
585535003163	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
585535003164	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
585535003165	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
585535003166	active site
585535003167	HIGH motif; other site
585535003168	KMSKS motif; other site
585535003169	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
585535003170	anticodon binding site; other site
585535003171	tRNA binding surface [nucleotide binding]; other site
585535003172	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
585535003173	dimer interface [polypeptide binding]; other site
585535003174	putative tRNA-binding site [nucleotide binding]; other site
585535003175	Mycolic acid cyclopropane synthetase; Region: CMAS; pfam02353
585535003176	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
585535003177	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585535003178	S-adenosylmethionine binding site [chemical binding]; other site
585535003179	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
585535003180	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585535003181	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
585535003182	GMP synthase; Reviewed; Region: guaA; PRK00074
585535003183	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
585535003184	AMP/PPi binding site [chemical binding]; other site
585535003185	candidate oxyanion hole; other site
585535003186	catalytic triad [active]
585535003187	potential glutamine specificity residues [chemical binding]; other site
585535003188	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
585535003189	ATP Binding subdomain [chemical binding]; other site
585535003190	Ligand Binding sites [chemical binding]; other site
585535003191	Dimerization subdomain; other site
585535003192	Protein of unknown function (DUF3972); Region: DUF3972; pfam13118
585535003193	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
585535003194	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
585535003195	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585535003196	catalytic residue [active]
585535003197	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
585535003198	nucleotide binding site/active site [active]
585535003199	HIT family signature motif; other site
585535003200	catalytic residue [active]
585535003201	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
585535003202	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
585535003203	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
585535003204	dimer interface [polypeptide binding]; other site
585535003205	motif 1; other site
585535003206	active site
585535003207	motif 2; other site
585535003208	motif 3; other site
585535003209	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
585535003210	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
585535003211	putative tRNA-binding site [nucleotide binding]; other site
585535003212	tRNA synthetase B5 domain; Region: B5; pfam03484
585535003213	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
585535003214	dimer interface [polypeptide binding]; other site
585535003215	motif 1; other site
585535003216	motif 3; other site
585535003217	motif 2; other site
585535003218	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
585535003219	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
585535003220	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
585535003221	hinge; other site
585535003222	active site
585535003223	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
585535003224	LytB protein; Region: LYTB; pfam02401
585535003225	ribosomal protein S1; Region: rpsA; TIGR00717
585535003226	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
585535003227	RNA binding site [nucleotide binding]; other site
585535003228	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
585535003229	RNA binding site [nucleotide binding]; other site
585535003230	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
585535003231	RNA binding site [nucleotide binding]; other site
585535003232	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
585535003233	RNA binding site [nucleotide binding]; other site
585535003234	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
585535003235	RNA binding site [nucleotide binding]; other site
585535003236	D-3-phosphoglycerate dehydrogenase; Region: PGDH; TIGR01327
585535003237	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
585535003238	ligand binding site [chemical binding]; other site
585535003239	NAD binding site [chemical binding]; other site
585535003240	dimerization interface [polypeptide binding]; other site
585535003241	catalytic site [active]
585535003242	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
585535003243	putative L-serine binding site [chemical binding]; other site
585535003244	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
585535003245	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
585535003246	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
585535003247	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585535003248	catalytic residue [active]
585535003249	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
585535003250	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
585535003251	putative active site [active]
585535003252	putative metal binding site [ion binding]; other site
585535003253	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
585535003254	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
585535003255	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585535003256	active site
585535003257	phosphorylation site [posttranslational modification]
585535003258	intermolecular recognition site; other site
585535003259	dimerization interface [polypeptide binding]; other site
585535003260	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
585535003261	putative binding surface; other site
585535003262	active site
585535003263	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
585535003264	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
585535003265	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585535003266	ATP binding site [chemical binding]; other site
585535003267	Mg2+ binding site [ion binding]; other site
585535003268	G-X-G motif; other site
585535003269	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
585535003270	Response regulator receiver domain; Region: Response_reg; pfam00072
585535003271	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585535003272	active site
585535003273	phosphorylation site [posttranslational modification]
585535003274	intermolecular recognition site; other site
585535003275	dimerization interface [polypeptide binding]; other site
585535003276	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
585535003277	putative CheA interaction surface; other site
585535003278	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
585535003279	dimer interface [polypeptide binding]; other site
585535003280	catalytic triad [active]
585535003281	peroxidatic and resolving cysteines [active]
585535003282	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
585535003283	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
585535003284	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
585535003285	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585535003286	S-adenosylmethionine binding site [chemical binding]; other site
585535003287	primosome assembly protein PriA; Validated; Region: PRK05580
585535003288	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585535003289	ATP binding site [chemical binding]; other site
585535003290	putative Mg++ binding site [ion binding]; other site
585535003291	helicase superfamily c-terminal domain; Region: HELICc; smart00490
585535003292	Sporulation related domain; Region: SPOR; pfam05036
585535003293	Peptidase family M48; Region: Peptidase_M48; pfam01435
585535003294	HemK family putative methylases; Region: hemK_fam; TIGR00536
585535003295	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
585535003296	glutamate dehydrogenase; Provisional; Region: PRK09414
585535003297	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
585535003298	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
585535003299	NAD(P) binding site [chemical binding]; other site
585535003300	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
585535003301	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
585535003302	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
585535003303	SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide...; Region: SoxW; cd02951
585535003304	catalytic residues [active]
585535003305	ferrochelatase; Region: hemH; TIGR00109
585535003306	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
585535003307	C-terminal domain interface [polypeptide binding]; other site
585535003308	active site
585535003309	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
585535003310	active site
585535003311	N-terminal domain interface [polypeptide binding]; other site
585535003312	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
585535003313	RNA methyltransferase, RsmE family; Region: TIGR00046
585535003314	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535003315	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
585535003316	trimer interface [polypeptide binding]; other site
585535003317	active site
585535003318	acetyl-CoA carboxylase, biotin carboxyl carrier protein; Region: BCCP; TIGR00531
585535003319	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
585535003320	carboxyltransferase (CT) interaction site; other site
585535003321	biotinylation site [posttranslational modification]; other site
585535003322	biotin carboxylase; Validated; Region: PRK08462
585535003323	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
585535003324	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
585535003325	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
585535003326	Methyltransferase domain; Region: Methyltransf_26; pfam13659
585535003327	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
585535003328	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
585535003329	inhibitor-cofactor binding pocket; inhibition site
585535003330	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585535003331	catalytic residue [active]
585535003332	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
585535003333	dimer interface [polypeptide binding]; other site
585535003334	putative radical transfer pathway; other site
585535003335	diiron center [ion binding]; other site
585535003336	tyrosyl radical; other site
585535003337	protein-L-isoaspartate(D-aspartate) O-methyltransferase; Region: pimt; TIGR00080
585535003338	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585535003339	S-adenosylmethionine binding site [chemical binding]; other site
585535003340	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
585535003341	Predicted permeases [General function prediction only]; Region: COG0795
585535003342	tRNA pseudouridine(38-40) synthase; Region: hisT_truA; TIGR00071
585535003343	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
585535003344	dimerization interface 3.5A [polypeptide binding]; other site
585535003345	active site
585535003346	UDP-glucose-4-epimerase GalE; Region: galE; TIGR01179
585535003347	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
585535003348	NAD binding site [chemical binding]; other site
585535003349	homodimer interface [polypeptide binding]; other site
585535003350	active site
585535003351	substrate binding site [chemical binding]; other site
585535003352	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
585535003353	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
585535003354	putative NAD(P) binding site [chemical binding]; other site
585535003355	homodimer interface [polypeptide binding]; other site
585535003356	homotetramer interface [polypeptide binding]; other site
585535003357	active site
585535003358	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585535003359	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585535003360	binding surface
585535003361	TPR motif; other site
585535003362	Sel1-like repeats; Region: SEL1; smart00671
585535003363	Sel1-like repeats; Region: SEL1; smart00671
585535003364	Sel1-like repeats; Region: SEL1; smart00671
585535003365	Entner-Doudoroff aldolase; Region: eda; TIGR01182
585535003366	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
585535003367	active site
585535003368	intersubunit interface [polypeptide binding]; other site
585535003369	catalytic residue [active]
585535003370	phosphogluconate dehydratase; Validated; Region: PRK09054
585535003371	6-phosphogluconate dehydratase; Region: edd; TIGR01196
585535003372	Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Region: Zwf; COG0364
585535003373	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
585535003374	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
585535003375	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
585535003376	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
585535003377	putative active site [active]
585535003378	glucokinase, proteobacterial type; Region: glk; TIGR00749
585535003379	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585535003380	nucleotide binding site [chemical binding]; other site
585535003381	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
585535003382	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
585535003383	putative NAD(P) binding site [chemical binding]; other site
585535003384	putative substrate binding site [chemical binding]; other site
585535003385	catalytic Zn binding site [ion binding]; other site
585535003386	structural Zn binding site [ion binding]; other site
585535003387	dimer interface [polypeptide binding]; other site
585535003388	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
585535003389	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
585535003390	active site
585535003391	variable size of poly A (14A/13A) between reads; Unresolved repeat
585535003392	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535003393	pyruvate flavodoxin oxidoreductase subunit gamma; Validated; Region: PRK05844
585535003394	pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; Provisional; Region: PRK14029
585535003395	pyruvate flavodoxin oxidoreductase subunit delta; Reviewed; Region: porD; PRK09625
585535003396	4Fe-4S binding domain; Region: Fer4; pfam00037
585535003397	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
585535003398	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
585535003399	dimer interface [polypeptide binding]; other site
585535003400	PYR/PP interface [polypeptide binding]; other site
585535003401	TPP binding site [chemical binding]; other site
585535003402	substrate binding site [chemical binding]; other site
585535003403	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
585535003404	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
585535003405	Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea...; Region: TPP_PFOR_porB_like; cd03376
585535003406	TPP-binding site [chemical binding]; other site
585535003407	putative dimer interface [polypeptide binding]; other site
585535003408	adenylosuccinate lyase; Provisional; Region: PRK08470
585535003409	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
585535003410	tetramer interface [polypeptide binding]; other site
585535003411	active site
585535003412	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
585535003413	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535003414	excinuclease ABC subunit B; Provisional; Region: PRK05298
585535003415	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585535003416	ATP binding site [chemical binding]; other site
585535003417	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
585535003418	putative Mg++ binding site [ion binding]; other site
585535003419	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585535003420	nucleotide binding region [chemical binding]; other site
585535003421	ATP-binding site [chemical binding]; other site
585535003422	Ultra-violet resistance protein B; Region: UvrB; pfam12344
585535003423	UvrB/uvrC motif; Region: UVR; pfam02151
585535003424	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585535003425	binding surface
585535003426	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585535003427	TPR motif; other site
585535003428	Sel1-like repeats; Region: SEL1; smart00671
585535003429	Sel1-like repeats; Region: SEL1; smart00671
585535003430	Sel1-like repeats; Region: SEL1; smart00671
585535003431	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
585535003432	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
585535003433	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08471
585535003434	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
585535003435	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
585535003436	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
585535003437	cofactor binding site; other site
585535003438	DNA binding site [nucleotide binding]
585535003439	substrate interaction site [chemical binding]; other site
585535003440	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
585535003441	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
585535003442	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
585535003443	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
585535003444	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
585535003445	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585535003446	ligand binding site [chemical binding]; other site
585535003447	translocation protein TolB; Provisional; Region: tolB; PRK04043
585535003448	TolB amino-terminal domain; Region: TolB_N; pfam04052
585535003449	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
585535003450	TonB C terminal; Region: TonB_2; pfam13103
585535003451	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
585535003452	TolR protein; Region: tolR; TIGR02801
585535003453	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
585535003454	ATP synthase, F1 epsilon subunit (delta in mitochondria); Region: ATP_synt_epsi; TIGR01216
585535003455	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
585535003456	gamma subunit interface [polypeptide binding]; other site
585535003457	epsilon subunit interface [polypeptide binding]; other site
585535003458	LBP interface [polypeptide binding]; other site
585535003459	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
585535003460	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
585535003461	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
585535003462	alpha subunit interaction interface [polypeptide binding]; other site
585535003463	Walker A motif; other site
585535003464	ATP binding site [chemical binding]; other site
585535003465	Walker B motif; other site
585535003466	inhibitor binding site; inhibition site
585535003467	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
585535003468	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
585535003469	core domain interface [polypeptide binding]; other site
585535003470	delta subunit interface [polypeptide binding]; other site
585535003471	epsilon subunit interface [polypeptide binding]; other site
585535003472	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
585535003473	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
585535003474	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
585535003475	beta subunit interaction interface [polypeptide binding]; other site
585535003476	Walker A motif; other site
585535003477	ATP binding site [chemical binding]; other site
585535003478	Walker B motif; other site
585535003479	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
585535003480	F0F1 ATP synthase subunit delta; Provisional; Region: PRK13431
585535003481	F0F1 ATP synthase subunit B; Validated; Region: PRK08475
585535003482	ATP synthase B/B' CF(0); Region: ATP-synt_B; pfam00430
585535003483	F0F1 ATP synthase subunit B'; Validated; Region: PRK08476
585535003484	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
585535003485	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
585535003486	ParB-like nuclease domain; Region: ParB; smart00470
585535003487	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
585535003488	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
585535003489	P-loop; other site
585535003490	Magnesium ion binding site [ion binding]; other site
585535003491	biotin--protein ligase; Provisional; Region: PRK08477
585535003492	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
585535003493	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
585535003494	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
585535003495	putative active site [active]
585535003496	substrate binding site [chemical binding]; other site
585535003497	putative cosubstrate binding site; other site
585535003498	catalytic site [active]
585535003499	Formyl transferase, C-terminal domain; Region: Formyl_trans_C; pfam02911
585535003500	PHP-associated; Region: PHP_C; pfam13263
585535003501	AAA domain; Region: AAA_23; pfam13476
585535003502	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585535003503	Walker A/P-loop; other site
585535003504	ATP binding site [chemical binding]; other site
585535003505	AAA domain; Region: AAA_21; pfam13304
585535003506	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
585535003507	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
585535003508	Uncharacterized conserved protein [Function unknown]; Region: COG1432
585535003509	LabA_like proteins; Region: LabA_like; cd06167
585535003510	putative metal binding site [ion binding]; other site
585535003511	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
585535003512	tRNA (Guanine-1)-methyltransferase; Region: tRNA_m1G_MT; cl00407
585535003513	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK14593
585535003514	RimM N-terminal domain; Region: RimM; pfam01782
585535003515	PRC-barrel domain; Region: PRC; pfam05239
585535003516	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
585535003517	KH domain; Region: KH_4; pfam13083
585535003518	G-X-X-G motif; other site
585535003519	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
585535003520	signal recognition particle protein; Provisional; Region: PRK10867
585535003521	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
585535003522	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
585535003523	P loop; other site
585535003524	GTP binding site [chemical binding]; other site
585535003525	Signal peptide binding domain; Region: SRP_SPB; pfam02978
585535003526	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
585535003527	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
585535003528	active site
585535003529	HIGH motif; other site
585535003530	nucleotide binding site [chemical binding]; other site
585535003531	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
585535003532	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
585535003533	active site
585535003534	KMSKS motif; other site
585535003535	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
585535003536	anticodon binding site; other site
585535003537	flagellar assembly protein FliW; Provisional; Region: PRK13283
585535003538	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
585535003539	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
585535003540	active site
585535003541	homodimer interface [polypeptide binding]; other site
585535003542	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535003543	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535003544	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
585535003545	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
585535003546	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
585535003547	Fic/DOC family; Region: Fic; cl00960
585535003548	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
585535003549	active site
585535003550	iron coordination sites [ion binding]; other site
585535003551	substrate binding pocket [chemical binding]; other site
585535003552	Uncharacterized conserved protein [Function unknown]; Region: COG4278
585535003553	metal-binding heat shock protein; Provisional; Region: PRK00016
585535003554	flavodoxin FldA; Validated; Region: PRK09267
585535003555	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
585535003556	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
585535003557	Uncharacterized protein, possibly involved in nitrogen fixation [Inorganic ion transport and metabolism]; Region: FixS; COG3197
585535003558	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
585535003559	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585535003560	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585535003561	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
585535003562	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
585535003563	active site
585535003564	dimer interface [polypeptide binding]; other site
585535003565	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
585535003566	dimer interface [polypeptide binding]; other site
585535003567	active site
585535003568	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
585535003569	carbon starvation protein A; Provisional; Region: PRK15015
585535003570	Carbon starvation protein CstA; Region: CstA; pfam02554
585535003571	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
585535003572	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585535003573	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585535003574	dimer interface [polypeptide binding]; other site
585535003575	conserved gate region; other site
585535003576	putative PBP binding loops; other site
585535003577	ABC-ATPase subunit interface; other site
585535003578	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585535003579	dimer interface [polypeptide binding]; other site
585535003580	conserved gate region; other site
585535003581	putative PBP binding loops; other site
585535003582	ABC-ATPase subunit interface; other site
585535003583	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
585535003584	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
585535003585	Walker A/P-loop; other site
585535003586	ATP binding site [chemical binding]; other site
585535003587	Q-loop/lid; other site
585535003588	ABC transporter signature motif; other site
585535003589	Walker B; other site
585535003590	D-loop; other site
585535003591	H-loop/switch region; other site
585535003592	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
585535003593	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585535003594	substrate binding pocket [chemical binding]; other site
585535003595	membrane-bound complex binding site; other site
585535003596	hinge residues; other site
585535003597	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
585535003598	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585535003599	putative substrate translocation pore; other site
585535003600	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
585535003601	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535003602	purine-nucleoside phosphorylase, family 1 (deoD); Region: deoD; TIGR00107
585535003603	phosphopentomutase; Provisional; Region: PRK05362
585535003604	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
585535003605	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
585535003606	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
585535003607	Nucleoside recognition; Region: Gate; pfam07670
585535003608	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
585535003609	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585535003610	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585535003611	putative substrate translocation pore; other site
585535003612	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
585535003613	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
585535003614	Ligand Binding Site [chemical binding]; other site
585535003615	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
585535003616	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
585535003617	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
585535003618	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
585535003619	putative arabinose transporter; Provisional; Region: PRK03545
585535003620	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585535003621	putative substrate translocation pore; other site
585535003622	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
585535003623	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
585535003624	active site
585535003625	zinc binding site [ion binding]; other site
585535003626	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
585535003627	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
585535003628	aspartate-semialdehyde dehydrogenase (peptidoglycan organisms); Region: asd_B; TIGR01296
585535003629	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
585535003630	Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: HisS; COG0124
585535003631	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
585535003632	dimer interface [polypeptide binding]; other site
585535003633	motif 1; other site
585535003634	active site
585535003635	motif 2; other site
585535003636	motif 3; other site
585535003637	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
585535003638	anticodon binding site; other site
585535003639	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
585535003640	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
585535003641	putative active site [active]
585535003642	elongation factor G; Reviewed; Region: PRK00007
585535003643	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
585535003644	G1 box; other site
585535003645	putative GEF interaction site [polypeptide binding]; other site
585535003646	GTP/Mg2+ binding site [chemical binding]; other site
585535003647	Switch I region; other site
585535003648	G2 box; other site
585535003649	G3 box; other site
585535003650	Switch II region; other site
585535003651	G4 box; other site
585535003652	G5 box; other site
585535003653	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
585535003654	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
585535003655	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
585535003656	30S ribosomal protein S7; Validated; Region: PRK05302
585535003657	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
585535003658	S17 interaction site [polypeptide binding]; other site
585535003659	S8 interaction site; other site
585535003660	16S rRNA interaction site [nucleotide binding]; other site
585535003661	streptomycin interaction site [chemical binding]; other site
585535003662	23S rRNA interaction site [nucleotide binding]; other site
585535003663	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
585535003664	bifunctional DNA-directed RNA polymerase subunit beta/beta'; Reviewed; Region: PRK09603
585535003665	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
585535003666	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
585535003667	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
585535003668	RPB11 interaction site [polypeptide binding]; other site
585535003669	RPB12 interaction site [polypeptide binding]; other site
585535003670	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
585535003671	RPB3 interaction site [polypeptide binding]; other site
585535003672	RPB1 interaction site [polypeptide binding]; other site
585535003673	RPB11 interaction site [polypeptide binding]; other site
585535003674	RPB10 interaction site [polypeptide binding]; other site
585535003675	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
585535003676	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
585535003677	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
585535003678	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
585535003679	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
585535003680	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
585535003681	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
585535003682	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
585535003683	DNA binding site [nucleotide binding]
585535003684	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
585535003685	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
585535003686	L11 interface [polypeptide binding]; other site
585535003687	putative EF-Tu interaction site [polypeptide binding]; other site
585535003688	putative EF-G interaction site [polypeptide binding]; other site
585535003689	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
585535003690	23S rRNA interface [nucleotide binding]; other site
585535003691	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
585535003692	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
585535003693	mRNA/rRNA interface [nucleotide binding]; other site
585535003694	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
585535003695	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
585535003696	23S rRNA interface [nucleotide binding]; other site
585535003697	L7/L12 interface [polypeptide binding]; other site
585535003698	putative thiostrepton binding site; other site
585535003699	L25 interface [polypeptide binding]; other site
585535003700	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
585535003701	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
585535003702	putative homodimer interface [polypeptide binding]; other site
585535003703	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
585535003704	heterodimer interface [polypeptide binding]; other site
585535003705	homodimer interface [polypeptide binding]; other site
585535003706	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; cl00481
585535003707	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
585535003708	elongation factor Tu; Reviewed; Region: PRK00049
585535003709	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
585535003710	G1 box; other site
585535003711	GEF interaction site [polypeptide binding]; other site
585535003712	GTP/Mg2+ binding site [chemical binding]; other site
585535003713	Switch I region; other site
585535003714	G2 box; other site
585535003715	G3 box; other site
585535003716	Switch II region; other site
585535003717	G4 box; other site
585535003718	G5 box; other site
585535003719	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
585535003720	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
585535003721	Antibiotic Binding Site [chemical binding]; other site
585535003722	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
585535003723	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
585535003724	Walker A/P-loop; other site
585535003725	ATP binding site [chemical binding]; other site
585535003726	Q-loop/lid; other site
585535003727	ABC transporter signature motif; other site
585535003728	Walker B; other site
585535003729	D-loop; other site
585535003730	H-loop/switch region; other site
585535003731	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
585535003732	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
585535003733	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
585535003734	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; pfam02086
585535003735	Helicobacter pylori IceA2 protein; Region: IceA2; pfam05862
585535003736	serine O-acetyltransferase; Region: cysE; TIGR01172
585535003737	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
585535003738	trimer interface [polypeptide binding]; other site
585535003739	active site
585535003740	substrate binding site [chemical binding]; other site
585535003741	CoA binding site [chemical binding]; other site
585535003742	F0F1 ATP synthase subunit C; Validated; Region: PRK08482
585535003743	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
585535003744	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
585535003745	oligomer interface [polypeptide binding]; other site
585535003746	RNA binding site [nucleotide binding]; other site
585535003747	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
585535003748	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
585535003749	oligomer interface [polypeptide binding]; other site
585535003750	RNA binding site [nucleotide binding]; other site
585535003751	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
585535003752	putative nucleic acid binding region [nucleotide binding]; other site
585535003753	G-X-X-G motif; other site
585535003754	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
585535003755	RNA binding site [nucleotide binding]; other site
585535003756	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG1926
585535003757	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
585535003758	Organic solvent tolerance protein; Region: OstA_C; pfam04453
585535003759	Predicted membrane protein/domain [Function unknown]; Region: COG1714
585535003760	phosphoribosylamine--glycine ligase; Region: purD; TIGR00877
585535003761	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
585535003762	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
585535003763	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
585535003764	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
585535003765	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
585535003766	Walker A/P-loop; other site
585535003767	ATP binding site [chemical binding]; other site
585535003768	Q-loop/lid; other site
585535003769	ABC transporter signature motif; other site
585535003770	Walker B; other site
585535003771	D-loop; other site
585535003772	H-loop/switch region; other site
585535003773	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
585535003774	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
585535003775	catalytic residue [active]
585535003776	putative FPP diphosphate  binding site; other site
585535003777	putative FPP binding hydrophobic cleft; other site
585535003778	dimer interface [polypeptide binding]; other site
585535003779	putative IPP diphosphate binding site; other site
585535003780	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
585535003781	FAD binding domain; Region: FAD_binding_4; pfam01565
585535003782	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
585535003783	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
585535003784	active site residue [active]
585535003785	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
585535003786	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
585535003787	active site
585535003788	camphor resistance protein CrcB; Provisional; Region: PRK14204
585535003789	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
585535003790	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585535003791	FeS/SAM binding site; other site
585535003792	Cytochrome c553 [Energy production and conversion]; Region: COG2863
585535003793	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
585535003794	putative active site [active]
585535003795	Ap4A binding site [chemical binding]; other site
585535003796	nudix motif; other site
585535003797	putative metal binding site [ion binding]; other site
585535003798	aspartate kinase; Reviewed; Region: PRK06635
585535003799	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
585535003800	putative nucleotide binding site [chemical binding]; other site
585535003801	putative catalytic residues [active]
585535003802	putative Mg ion binding site [ion binding]; other site
585535003803	putative aspartate binding site [chemical binding]; other site
585535003804	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
585535003805	putative allosteric regulatory site; other site
585535003806	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
585535003807	putative allosteric regulatory residue; other site
585535003808	DNA replication regulator; Region: HobA; pfam12163
585535003809	DNA polymerase III subunit delta'; Validated; Region: PRK08485
585535003810	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
585535003811	dihydropteroate synthase; Region: DHPS; TIGR01496
585535003812	substrate binding pocket [chemical binding]; other site
585535003813	dimer interface [polypeptide binding]; other site
585535003814	inhibitor binding site; inhibition site
585535003815	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
585535003816	EamA-like transporter family; Region: EamA; pfam00892
585535003817	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
585535003818	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2952
585535003819	Carbamoylphosphate synthase small subunit [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarA; COG0505
585535003820	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
585535003821	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
585535003822	catalytic site [active]
585535003823	subunit interface [polypeptide binding]; other site
585535003824	formamidase; Provisional; Region: amiF; PRK13287
585535003825	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
585535003826	multimer interface [polypeptide binding]; other site
585535003827	active site
585535003828	catalytic triad [active]
585535003829	dimer interface [polypeptide binding]; other site
585535003830	Maf-like protein; Region: Maf; pfam02545
585535003831	Maf-like protein; Reviewed; Region: PRK04056
585535003832	putative active site [active]
585535003833	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
585535003834	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
585535003835	motif 1; other site
585535003836	active site
585535003837	motif 2; other site
585535003838	motif 3; other site
585535003839	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
585535003840	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
585535003841	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
585535003842	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
585535003843	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
585535003844	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
585535003845	dimer interface [polypeptide binding]; other site
585535003846	ssDNA binding site [nucleotide binding]; other site
585535003847	tetramer (dimer of dimers) interface [polypeptide binding]; other site
585535003848	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
585535003849	DNA polymerase III subunit delta; Validated; Region: PRK08487
585535003850	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
585535003851	Exoribonuclease R [Transcription]; Region: VacB; COG0557
585535003852	RNB domain; Region: RNB; pfam00773
585535003853	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
585535003854	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
585535003855	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
585535003856	shikimate binding site; other site
585535003857	NAD(P) binding site [chemical binding]; other site
585535003858	Bacterial SH3 domain; Region: SH3_3; pfam08239
585535003859	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
585535003860	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585535003861	dimer interface [polypeptide binding]; other site
585535003862	conserved gate region; other site
585535003863	putative PBP binding loops; other site
585535003864	ABC-ATPase subunit interface; other site
585535003865	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
585535003866	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
585535003867	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
585535003868	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
585535003869	active site
585535003870	HIGH motif; other site
585535003871	dimer interface [polypeptide binding]; other site
585535003872	KMSKS motif; other site
585535003873	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
585535003874	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585535003875	S-adenosylmethionine binding site [chemical binding]; other site
585535003876	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
585535003877	ribosome recycling factor; Reviewed; Region: frr; PRK00083
585535003878	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
585535003879	hinge region; other site
585535003880	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585535003881	active site
585535003882	RDD family; Region: RDD; pfam06271
585535003883	NAD-dependent deacetylase; Provisional; Region: PRK00481
585535003884	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
585535003885	NAD+ binding site [chemical binding]; other site
585535003886	substrate binding site [chemical binding]; other site
585535003887	Zn binding site [ion binding]; other site
585535003888	NADH dehydrogenase subunit A; Validated; Region: PRK08489
585535003889	NADH dehydrogenase subunit B; Validated; Region: PRK06411
585535003890	NADH dehydrogenase subunit C; Provisional; Region: PRK08491
585535003891	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
585535003892	NADH dehydrogenase subunit D; Validated; Region: PRK06075
585535003893	NADH dehydrogenase I, D subunit; Region: NuoD; TIGR01962
585535003894	NADH dehydrogenase subunit G; Validated; Region: PRK08493
585535003895	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585535003896	catalytic loop [active]
585535003897	iron binding site [ion binding]; other site
585535003898	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
585535003899	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585535003900	molybdopterin cofactor binding site; other site
585535003901	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
585535003902	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
585535003903	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
585535003904	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
585535003905	4Fe-4S binding domain; Region: Fer4; cl02805
585535003906	4Fe-4S binding domain; Region: Fer4; pfam00037
585535003907	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
585535003908	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
585535003909	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
585535003910	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
585535003911	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
585535003912	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585535003913	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
585535003914	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585535003915	proton-translocating NADH-quinone oxidoreductase, chain N; Region: NDH_I_N; TIGR01770
585535003916	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585535003917	Outer membrane lipoprotein; Region: YfiO; pfam13525
585535003918	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
585535003919	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
585535003920	active site
585535003921	substrate binding site [chemical binding]; other site
585535003922	metal binding site [ion binding]; metal-binding site
585535003923	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
585535003924	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
585535003925	substrate binding site [chemical binding]; other site
585535003926	active site
585535003927	catalytic residues [active]
585535003928	heterodimer interface [polypeptide binding]; other site
585535003929	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
585535003930	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
585535003931	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585535003932	catalytic residue [active]
585535003933	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
585535003934	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
585535003935	active site
585535003936	ribulose/triose binding site [chemical binding]; other site
585535003937	phosphate binding site [ion binding]; other site
585535003938	substrate (anthranilate) binding pocket [chemical binding]; other site
585535003939	product (indole) binding pocket [chemical binding]; other site
585535003940	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
585535003941	active site
585535003942	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
585535003943	anthranilate phosphoribosyltransferase; Region: trpD; TIGR01245
585535003944	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
585535003945	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
585535003946	Glutamine amidotransferase class-I; Region: GATase; pfam00117
585535003947	glutamine binding [chemical binding]; other site
585535003948	catalytic triad [active]
585535003949	anthranilate synthase component I, proteobacterial subset; Region: trpE_proteo; TIGR00565
585535003950	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
585535003951	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
585535003952	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
585535003953	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
585535003954	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585535003955	active site
585535003956	motif I; other site
585535003957	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
585535003958	motif II; other site
585535003959	Uncharacterized conserved protein [Function unknown]; Region: COG2353
585535003960	thiaminase II; Region: salvage_TenA; TIGR04306
585535003961	Nicotinamide mononucleotide transporter [Coenzyme metabolism]; Region: PnuC; COG3201
585535003962	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
585535003963	Thiamine pyrophosphokinase; Region: TPK; cd07995
585535003964	active site
585535003965	dimerization interface [polypeptide binding]; other site
585535003966	thiamine binding site [chemical binding]; other site
585535003967	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
585535003968	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
585535003969	alphaNTD homodimer interface [polypeptide binding]; other site
585535003970	DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type; Region: rpoA; TIGR02027
585535003971	alphaNTD - beta interaction site [polypeptide binding]; other site
585535003972	alphaNTD - beta' interaction site [polypeptide binding]; other site
585535003973	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
585535003974	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
585535003975	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
585535003976	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585535003977	RNA binding surface [nucleotide binding]; other site
585535003978	30S ribosomal protein S11; Validated; Region: PRK05309
585535003979	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
585535003980	30S ribosomal protein S13; Region: bact_S13; TIGR03631
585535003981	Ribosomal protein L36; Region: Ribosomal_L36; cl00380
585535003982	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
585535003983	rRNA binding site [nucleotide binding]; other site
585535003984	predicted 30S ribosome binding site; other site
585535003985	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
585535003986	active site
585535003987	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
585535003988	SecY translocase; Region: SecY; pfam00344
585535003989	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
585535003990	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
585535003991	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
585535003992	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
585535003993	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
585535003994	23S rRNA interface [nucleotide binding]; other site
585535003995	5S rRNA interface [nucleotide binding]; other site
585535003996	L27 interface [polypeptide binding]; other site
585535003997	L5 interface [polypeptide binding]; other site
585535003998	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
585535003999	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
585535004000	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
585535004001	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
585535004002	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
585535004003	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
585535004004	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
585535004005	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
585535004006	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
585535004007	RNA binding site [nucleotide binding]; other site
585535004008	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
585535004009	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
585535004010	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
585535004011	putative translocon interaction site; other site
585535004012	23S rRNA interface [nucleotide binding]; other site
585535004013	signal recognition particle (SRP54) interaction site; other site
585535004014	L23 interface [polypeptide binding]; other site
585535004015	trigger factor interaction site; other site
585535004016	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
585535004017	23S rRNA interface [nucleotide binding]; other site
585535004018	5S rRNA interface [nucleotide binding]; other site
585535004019	putative antibiotic binding site [chemical binding]; other site
585535004020	L25 interface [polypeptide binding]; other site
585535004021	L27 interface [polypeptide binding]; other site
585535004022	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
585535004023	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
585535004024	G-X-X-G motif; other site
585535004025	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
585535004026	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
585535004027	putative translocon binding site; other site
585535004028	protein-rRNA interface [nucleotide binding]; other site
585535004029	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
585535004030	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
585535004031	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
585535004032	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
585535004033	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
585535004034	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
585535004035	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
585535004036	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
585535004037	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
585535004038	AAA domain; Region: AAA_14; pfam13173
585535004039	Helix-turn-helix domain; Region: HTH_36; pfam13730
585535004040	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
585535004041	RNA/DNA hybrid binding site [nucleotide binding]; other site
585535004042	active site
585535004043	fumarate hydratase; Reviewed; Region: fumC; PRK00485
585535004044	Class II fumarases; Region: Fumarase_classII; cd01362
585535004045	active site
585535004046	tetramer interface [polypeptide binding]; other site
585535004047	YtkA-like; Region: YtkA; pfam13115
585535004048	Outer membrane efflux protein; Region: OEP; pfam02321
585535004049	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
585535004050	HlyD family secretion protein; Region: HlyD_3; pfam13437
585535004051	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
585535004052	Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735
585535004053	AzlC protein; Region: AzlC; cl00570
585535004054	chaperone protein DnaJ; Provisional; Region: PRK14288
585535004055	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
585535004056	HSP70 interaction site [polypeptide binding]; other site
585535004057	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
585535004058	substrate binding site [polypeptide binding]; other site
585535004059	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
585535004060	Zn binding sites [ion binding]; other site
585535004061	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
585535004062	substrate binding site [polypeptide binding]; other site
585535004063	dimer interface [polypeptide binding]; other site
585535004064	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
585535004065	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
585535004066	Ligand Binding Site [chemical binding]; other site
585535004067	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
585535004068	HSP70 interaction site [polypeptide binding]; other site
585535004069	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
585535004070	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
585535004071	active site
585535004072	(T/H)XGH motif; other site
585535004073	nickel responsive regulator; Provisional; Region: PRK00630
585535004074	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
585535004075	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
585535004076	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
585535004077	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
585535004078	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
585535004079	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
585535004080	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
585535004081	DNA methylase; Region: N6_N4_Mtase; pfam01555
585535004082	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
585535004083	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957
585535004084	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
585535004085	Acylphosphatase; Region: Acylphosphatase; pfam00708
585535004086	[NiFe] hydrogenase maturation protein HypF; Region: hypF; TIGR00143
585535004087	HypF finger; Region: zf-HYPF; pfam07503
585535004088	HypF finger; Region: zf-HYPF; pfam07503
585535004089	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
585535004090	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
585535004091	dimerization interface [polypeptide binding]; other site
585535004092	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
585535004093	ATP binding site [chemical binding]; other site
585535004094	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
585535004095	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
585535004096	NADP binding site [chemical binding]; other site
585535004097	active site
585535004098	putative substrate binding site [chemical binding]; other site
585535004099	GDP-mannose 4,6-dehydratase; Region: gmd; TIGR01472
585535004100	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
585535004101	NADP-binding site; other site
585535004102	homotetramer interface [polypeptide binding]; other site
585535004103	substrate binding site [chemical binding]; other site
585535004104	homodimer interface [polypeptide binding]; other site
585535004105	active site
585535004106	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
585535004107	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
585535004108	Substrate binding site; other site
585535004109	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
585535004110	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
585535004111	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
585535004112	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
585535004113	VirB7 interaction site; other site
585535004114	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
585535004115	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
585535004116	PDZ domain; Region: PDZ_2; pfam13180
585535004117	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
585535004118	hypothetical protein; Provisional; Region: PRK03762
585535004119	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
585535004120	tetramerization interface [polypeptide binding]; other site
585535004121	active site
585535004122	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
585535004123	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535004124	Walker A motif; other site
585535004125	ATP binding site [chemical binding]; other site
585535004126	Walker B motif; other site
585535004127	arginine finger; other site
585535004128	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585535004129	Walker A motif; other site
585535004130	ATP binding site [chemical binding]; other site
585535004131	Walker B motif; other site
585535004132	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
585535004133	Uncharacterized conserved protein [Function unknown]; Region: COG2127
585535004134	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585535004135	Ligand Binding Site [chemical binding]; other site
585535004136	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
585535004137	AAA domain; Region: AAA_26; pfam13500
585535004138	Protein of unknown function (DUF1523); Region: DUF1523; pfam07509
585535004139	isocitrate dehydrogenase; Validated; Region: PRK07362
585535004140	isocitrate dehydrogenase; Reviewed; Region: PRK07006
585535004141	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
585535004142	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
585535004143	dimer interface [polypeptide binding]; other site
585535004144	active site
585535004145	citrylCoA binding site [chemical binding]; other site
585535004146	NADH binding [chemical binding]; other site
585535004147	cationic pore residues; other site
585535004148	oxalacetate/citrate binding site [chemical binding]; other site
585535004149	coenzyme A binding site [chemical binding]; other site
585535004150	catalytic triad [active]
585535004151	DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism]; Region: NUC1; COG1864
585535004152	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
585535004153	active site
585535004154	substrate binding site [chemical binding]; other site
585535004155	Type III restriction/modification enzyme methylation subunit; Region: TypeIII_RM_meth; pfam12564
585535004156	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
585535004157	DNA methylase; Region: N6_N4_Mtase; pfam01555
585535004158	DNA methylase; Region: N6_N4_Mtase; pfam01555
585535004159	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585535004160	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3421
585535004161	ATP binding site [chemical binding]; other site
585535004162	putative Mg++ binding site [ion binding]; other site
585535004163	biotin synthase; Provisional; Region: PRK08508
585535004164	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585535004165	FeS/SAM binding site; other site
585535004166	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
585535004167	YihY family inner membrane protein; Region: yihY_not_rbn; TIGR00765