-- dump date   	20140619_113049
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
765964000001	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
765964000002	putative RNA binding site [nucleotide binding]; other site
765964000003	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
765964000004	homopentamer interface [polypeptide binding]; other site
765964000005	active site
765964000006	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
765964000007	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
765964000008	active site clefts [active]
765964000009	zinc binding site [ion binding]; other site
765964000010	dimer interface [polypeptide binding]; other site
765964000011	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
765964000012	active site
765964000013	dimer interface [polypeptide binding]; other site
765964000014	pantoate--beta-alanine ligase; Region: panC; TIGR00018
765964000015	Pantoate-beta-alanine ligase; Region: PanC; cd00560
765964000016	active site
765964000017	ATP-binding site [chemical binding]; other site
765964000018	pantoate-binding site; other site
765964000019	HXXH motif; other site
765964000020	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
765964000021	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
765964000022	ring oligomerisation interface [polypeptide binding]; other site
765964000023	ATP/Mg binding site [chemical binding]; other site
765964000024	stacking interactions; other site
765964000025	hinge regions; other site
765964000026	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
765964000027	oligomerisation interface [polypeptide binding]; other site
765964000028	mobile loop; other site
765964000029	roof hairpin; other site
765964000030	DNA primase, catalytic core; Region: dnaG; TIGR01391
765964000031	CHC2 zinc finger; Region: zf-CHC2; pfam01807
765964000032	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
765964000033	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
765964000034	active site
765964000035	metal binding site [ion binding]; metal-binding site
765964000036	interdomain interaction site; other site
765964000037	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
765964000038	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
765964000039	Ligand Binding Site [chemical binding]; other site
765964000040	TrbC/VIRB2 family; Region: TrbC; cl01583
765964000041	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
765964000042	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
765964000043	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
765964000044	Walker A motif; other site
765964000045	ATP binding site [chemical binding]; other site
765964000046	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
765964000047	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
765964000048	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
765964000049	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
765964000050	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
765964000051	active site
765964000052	phosphorylation site [posttranslational modification]
765964000053	intermolecular recognition site; other site
765964000054	dimerization interface [polypeptide binding]; other site
765964000055	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
765964000056	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
765964000057	dimer interface [polypeptide binding]; other site
765964000058	active site
765964000059	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
765964000060	catalytic residues [active]
765964000061	substrate binding site [chemical binding]; other site
765964000062	lipid A 1-phosphatase; Reviewed; Region: PRK09597
765964000063	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
765964000064	active site
765964000065	lipid A phosphoethanolamine transferase; Reviewed; Region: PRK09598
765964000066	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
765964000067	Sulfatase; Region: Sulfatase; pfam00884
765964000068	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964000069	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
765964000070	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
765964000071	dimer interface [polypeptide binding]; other site
765964000072	active site
765964000073	citrylCoA binding site [chemical binding]; other site
765964000074	NADH binding [chemical binding]; other site
765964000075	cationic pore residues; other site
765964000076	oxalacetate/citrate binding site [chemical binding]; other site
765964000077	coenzyme A binding site [chemical binding]; other site
765964000078	catalytic triad [active]
765964000079	isocitrate dehydrogenase; Validated; Region: PRK07362
765964000080	isocitrate dehydrogenase; Reviewed; Region: PRK07006
765964000081	Protein of unknown function (DUF1523); Region: DUF1523; pfam07509
765964000082	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
765964000083	AAA domain; Region: AAA_26; pfam13500
765964000084	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
765964000085	Ligand Binding Site [chemical binding]; other site
765964000086	Uncharacterized conserved protein [Function unknown]; Region: COG2127
765964000087	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
765964000088	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964000089	Walker A motif; other site
765964000090	ATP binding site [chemical binding]; other site
765964000091	Walker B motif; other site
765964000092	arginine finger; other site
765964000093	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964000094	Walker A motif; other site
765964000095	ATP binding site [chemical binding]; other site
765964000096	Walker B motif; other site
765964000097	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
765964000098	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
765964000099	tetramerization interface [polypeptide binding]; other site
765964000100	active site
765964000101	hypothetical protein; Provisional; Region: PRK03762
765964000102	PDZ domain; Region: PDZ_2; pfam13180
765964000103	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
765964000104	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
765964000105	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
765964000106	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
765964000107	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
765964000108	VirB7 interaction site; other site
765964000109	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
765964000110	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
765964000111	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
765964000112	Substrate binding site; other site
765964000113	Cupin domain; Region: Cupin_2; cl17218
765964000114	GDP-mannose 4,6-dehydratase; Region: gmd; TIGR01472
765964000115	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
765964000116	NADP-binding site; other site
765964000117	homotetramer interface [polypeptide binding]; other site
765964000118	substrate binding site [chemical binding]; other site
765964000119	homodimer interface [polypeptide binding]; other site
765964000120	active site
765964000121	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
765964000122	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
765964000123	NADP binding site [chemical binding]; other site
765964000124	active site
765964000125	putative substrate binding site [chemical binding]; other site
765964000126	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
765964000127	dimerization interface [polypeptide binding]; other site
765964000128	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
765964000129	ATP binding site [chemical binding]; other site
765964000130	Acylphosphatase; Region: Acylphosphatase; pfam00708
765964000131	[NiFe] hydrogenase maturation protein HypF; Region: hypF; TIGR00143
765964000132	HypF finger; Region: zf-HYPF; pfam07503
765964000133	HypF finger; Region: zf-HYPF; pfam07503
765964000134	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
765964000135	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957
765964000136	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
765964000137	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
765964000138	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964000139	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
765964000140	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
765964000141	cofactor binding site; other site
765964000142	DNA binding site [nucleotide binding]
765964000143	substrate interaction site [chemical binding]; other site
765964000144	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
765964000145	potential frameshift: common BLAST hit: gi|210134247|ref|YP_002300686.1| restriction endonuclease
765964000146	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
765964000147	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964000148	Tsp45I type II restriction enzyme; Region: Tsp45I; pfam06300
765964000149	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
765964000150	cofactor binding site; other site
765964000151	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
765964000152	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
765964000153	Na binding site [ion binding]; other site
765964000154	Proline dehydrogenase; Region: Pro_dh; pfam01619
765964000155	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
765964000156	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
765964000157	Glutamate binding site [chemical binding]; other site
765964000158	NAD binding site [chemical binding]; other site
765964000159	catalytic residues [active]
765964000160	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
765964000161	potential frameshift: common BLAST hit: gi|15644696|ref|NP_206866.1| ATP-binding protein
765964000162	Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829
765964000163	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
765964000164	G1 box; other site
765964000165	GTP/Mg2+ binding site [chemical binding]; other site
765964000166	G2 box; other site
765964000167	Switch I region; other site
765964000168	G3 box; other site
765964000169	Switch II region; other site
765964000170	G4 box; other site
765964000171	G5 box; other site
765964000172	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
765964000173	UreF; Region: UreF; pfam01730
765964000174	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
765964000175	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
765964000176	dimer interface [polypeptide binding]; other site
765964000177	catalytic residues [active]
765964000178	AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293
765964000179	urease subunit beta; Provisional; Region: ureB; PRK13985
765964000180	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
765964000181	subunit interactions [polypeptide binding]; other site
765964000182	active site
765964000183	flap region; other site
765964000184	urease subunit alpha; Provisional; Region: PRK13986
765964000185	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
765964000186	alpha-gamma subunit interface [polypeptide binding]; other site
765964000187	beta-gamma subunit interface [polypeptide binding]; other site
765964000188	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
765964000189	gamma-beta subunit interface [polypeptide binding]; other site
765964000190	alpha-beta subunit interface [polypeptide binding]; other site
765964000191	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
765964000192	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14324
765964000193	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
765964000194	active site
765964000195	substrate binding site [chemical binding]; other site
765964000196	metal binding site [ion binding]; metal-binding site
765964000197	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
765964000198	peptide chain release factor 1; Validated; Region: prfA; PRK00591
765964000199	This domain is found in peptide chain release factors; Region: PCRF; smart00937
765964000200	RF-1 domain; Region: RF-1; pfam00472
765964000201	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964000202	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
765964000203	dimer interface [polypeptide binding]; other site
765964000204	putative CheW interface [polypeptide binding]; other site
765964000205	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
765964000206	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
765964000207	23S rRNA interface [nucleotide binding]; other site
765964000208	L3 interface [polypeptide binding]; other site
765964000209	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
765964000210	Predicted dehydrogenase [General function prediction only]; Region: COG0579
765964000211	NLPC_P60 stabilising domain, N term; Region: N_NLPC_P60; pfam12912
765964000212	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
765964000213	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
765964000214	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
765964000215	NlpC/P60 family; Region: NLPC_P60; cl17555
765964000216	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
765964000217	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
765964000218	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
765964000219	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
765964000220	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
765964000221	DNA binding residues [nucleotide binding]
765964000222	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
765964000223	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
765964000224	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
765964000225	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
765964000226	potential protein location (hypothetical protein HPCU_00420 [Helicobacter pylori Cuz20]) that overlaps RNA (tRNA-S)
765964000227	DpnII restriction endonuclease; Region: DpnII; pfam04556
765964000228	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
765964000229	Methyltransferase domain; Region: Methyltransf_26; pfam13659
765964000230	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964000231	potential frameshift: common BLAST hit: gi|188526899|ref|YP_001909586.1| alpha-1,2-fucosyltransferase
765964000232	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
765964000233	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
765964000234	putative ligand binding site [chemical binding]; other site
765964000235	putative NAD binding site [chemical binding]; other site
765964000236	catalytic site [active]
765964000237	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
765964000238	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
765964000239	pyridoxal 5'-phosphate binding site [chemical binding]; other site
765964000240	catalytic residue [active]
765964000241	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
765964000242	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
765964000243	dimer interface [polypeptide binding]; other site
765964000244	putative CheW interface [polypeptide binding]; other site
765964000245	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases and ATP sulphurylases. The domain forms a apha/beta/apha fold which  binds to Adenosine group; Region: Alpha_ANH_like; cd01986
765964000246	Ligand Binding Site [chemical binding]; other site
765964000247	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964000248	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
765964000249	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
765964000250	metal-binding site
765964000251	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
765964000252	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
765964000253	dimerization interface [polypeptide binding]; other site
765964000254	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
765964000255	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
765964000256	dimer interface [polypeptide binding]; other site
765964000257	putative CheW interface [polypeptide binding]; other site
765964000258	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
765964000259	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
765964000260	active site
765964000261	metal binding site [ion binding]; metal-binding site
765964000262	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
765964000263	S-ribosylhomocysteinase; Provisional; Region: PRK02260
765964000264	cystathionine gamma-synthase/cystathionine beta-lyase; Validated; Region: PRK06176
765964000265	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
765964000266	homodimer interface [polypeptide binding]; other site
765964000267	substrate-cofactor binding pocket; other site
765964000268	pyridoxal 5'-phosphate binding site [chemical binding]; other site
765964000269	catalytic residue [active]
765964000270	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
765964000271	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
765964000272	dimer interface [polypeptide binding]; other site
765964000273	pyridoxal 5'-phosphate binding site [chemical binding]; other site
765964000274	catalytic residue [active]
765964000275	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
765964000276	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
765964000277	nucleotide binding site [chemical binding]; other site
765964000278	NEF interaction site [polypeptide binding]; other site
765964000279	SBD interface [polypeptide binding]; other site
765964000280	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
765964000281	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
765964000282	dimer interface [polypeptide binding]; other site
765964000283	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
765964000284	heat-inducible transcription repressor; Provisional; Region: PRK03911
765964000285	hypothetical protein; Provisional; Region: PRK05834
765964000286	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
765964000287	flagellin B; Provisional; Region: PRK13588
765964000288	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
765964000289	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
765964000290	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
765964000291	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
765964000292	DNA topoisomerase I; Validated; Region: PRK05582
765964000293	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
765964000294	active site
765964000295	interdomain interaction site; other site
765964000296	putative metal-binding site [ion binding]; other site
765964000297	nucleotide binding site [chemical binding]; other site
765964000298	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
765964000299	domain I; other site
765964000300	DNA binding groove [nucleotide binding]
765964000301	phosphate binding site [ion binding]; other site
765964000302	domain II; other site
765964000303	domain III; other site
765964000304	nucleotide binding site [chemical binding]; other site
765964000305	catalytic site [active]
765964000306	domain IV; other site
765964000307	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
765964000308	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
765964000309	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
765964000310	Fe-S oxidoreductases [Energy production and conversion]; Region: COG0731
765964000311	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
765964000312	FeS/SAM binding site; other site
765964000313	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
765964000314	phosphoenolpyruvate synthase; Validated; Region: PRK06464
765964000315	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
765964000316	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
765964000317	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
765964000318	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
765964000319	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
765964000320	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
765964000321	active site
765964000322	dimer interface [polypeptide binding]; other site
765964000323	motif 1; other site
765964000324	motif 2; other site
765964000325	motif 3; other site
765964000326	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
765964000327	anticodon binding site; other site
765964000328	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
765964000329	translation initiation factor IF-3; Region: infC; TIGR00168
765964000330	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
765964000331	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
765964000332	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
765964000333	23S rRNA binding site [nucleotide binding]; other site
765964000334	L21 binding site [polypeptide binding]; other site
765964000335	L13 binding site [polypeptide binding]; other site
765964000336	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964000337	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
765964000338	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
765964000339	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
765964000340	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
765964000341	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
765964000342	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
765964000343	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroG; COG3200
765964000344	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
765964000345	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
765964000346	catalytic triad [active]
765964000347	Uncharacterized conserved protein [Function unknown]; Region: COG1556
765964000348	iron-sulfur cluster-binding protein; Region: TIGR00273
765964000349	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
765964000350	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
765964000351	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
765964000352	Cysteine-rich domain; Region: CCG; pfam02754
765964000353	Cysteine-rich domain; Region: CCG; pfam02754
765964000354	L-lactate transport; Region: lctP; TIGR00795
765964000355	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
765964000356	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
765964000357	L-lactate permease; Region: Lactate_perm; pfam02652
765964000358	DNA glycosylase MutY; Provisional; Region: PRK13910
765964000359	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
765964000360	minor groove reading motif; other site
765964000361	helix-hairpin-helix signature motif; other site
765964000362	substrate binding pocket [chemical binding]; other site
765964000363	active site
765964000364	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
765964000365	DNA binding and oxoG recognition site [nucleotide binding]
765964000366	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
765964000367	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
765964000368	transmembrane helices; other site
765964000369	cytochrome c oxidase, cbb3-type, subunit I; Region: ccoN; TIGR00780
765964000370	Low-spin heme binding site [chemical binding]; other site
765964000371	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
765964000372	D-pathway; other site
765964000373	Putative water exit pathway; other site
765964000374	Binuclear center (active site) [active]
765964000375	K-pathway; other site
765964000376	Putative proton exit pathway; other site
765964000377	Cbb3-type cytochrome oxidase, cytochrome c subunit [Energy production and conversion]; Region: CcoO; COG2993
765964000378	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; cl01130
765964000379	cytochrome c oxidase, cbb3-type, CcoQ subunit, epsilon-Proteobacterial; Region: cbb3_Q_epsi; TIGR02736
765964000380	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
765964000381	Cytochrome c; Region: Cytochrom_C; pfam00034
765964000382	Cytochrome c; Region: Cytochrom_C; pfam00034
765964000383	Family of unknown function (DUF4006); Region: DUF4006; pfam13179
765964000384	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
765964000385	recombinase A; Provisional; Region: recA; PRK09354
765964000386	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
765964000387	hexamer interface [polypeptide binding]; other site
765964000388	Walker A motif; other site
765964000389	ATP binding site [chemical binding]; other site
765964000390	Walker B motif; other site
765964000391	enolase; Provisional; Region: eno; PRK00077
765964000392	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
765964000393	dimer interface [polypeptide binding]; other site
765964000394	metal binding site [ion binding]; metal-binding site
765964000395	substrate binding pocket [chemical binding]; other site
765964000396	AMIN domain; Region: AMIN; pfam11741
765964000397	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
765964000398	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
765964000399	ADP binding site [chemical binding]; other site
765964000400	magnesium binding site [ion binding]; other site
765964000401	putative shikimate binding site; other site
765964000402	Cache domain; Region: Cache_1; pfam02743
765964000403	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
765964000404	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
765964000405	Ligand binding site; other site
765964000406	metal-binding site
765964000407	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
765964000408	Sel1 repeat; Region: Sel1; cl02723
765964000409	Sel1-like repeats; Region: SEL1; smart00671
765964000410	Sel1-like repeats; Region: SEL1; smart00671
765964000411	Sel1-like repeats; Region: SEL1; smart00671
765964000412	Sel1-like repeats; Region: SEL1; smart00671
765964000413	Sel1-like repeats; Region: SEL1; smart00671
765964000414	hypothetical protein; Provisional; Region: PRK12378
765964000415	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
765964000416	dimer interface [polypeptide binding]; other site
765964000417	active site
765964000418	Schiff base residues; other site
765964000419	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
765964000420	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
765964000421	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
765964000422	dimer interface [polypeptide binding]; other site
765964000423	phosphorylation site [posttranslational modification]
765964000424	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
765964000425	ATP binding site [chemical binding]; other site
765964000426	Mg2+ binding site [ion binding]; other site
765964000427	G-X-G motif; other site
765964000428	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
765964000429	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
765964000430	active site
765964000431	phosphorylation site [posttranslational modification]
765964000432	intermolecular recognition site; other site
765964000433	dimerization interface [polypeptide binding]; other site
765964000434	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
765964000435	DNA binding site [nucleotide binding]
765964000436	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
765964000437	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
765964000438	Peptidase family U32; Region: Peptidase_U32; pfam01136
765964000439	peptide chain release factor 2; Region: prfB; TIGR00020
765964000440	This domain is found in peptide chain release factors; Region: PCRF; smart00937
765964000441	RF-1 domain; Region: RF-1; pfam00472
765964000442	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
765964000443	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
765964000444	dimer interface [polypeptide binding]; other site
765964000445	putative functional site; other site
765964000446	putative MPT binding site; other site
765964000447	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
765964000448	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
765964000449	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
765964000450	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
765964000451	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
765964000452	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
765964000453	intersubunit interface [polypeptide binding]; other site
765964000454	active site
765964000455	zinc binding site [ion binding]; other site
765964000456	Na+ binding site [ion binding]; other site
765964000457	elongation factor P; Validated; Region: PRK00529
765964000458	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
765964000459	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
765964000460	RNA binding site [nucleotide binding]; other site
765964000461	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
765964000462	RNA binding site [nucleotide binding]; other site
765964000463	pseudaminic acid synthase; Region: PseI; TIGR03586
765964000464	NeuB family; Region: NeuB; pfam03102
765964000465	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
765964000466	NeuB binding interface [polypeptide binding]; other site
765964000467	putative substrate binding site [chemical binding]; other site
765964000468	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
765964000469	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
765964000470	Walker A/P-loop; other site
765964000471	ATP binding site [chemical binding]; other site
765964000472	Q-loop/lid; other site
765964000473	ABC transporter signature motif; other site
765964000474	Walker B; other site
765964000475	D-loop; other site
765964000476	H-loop/switch region; other site
765964000477	apolipoprotein N-acyltransferase; Reviewed; Region: PRK12291
765964000478	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
765964000479	active site
765964000480	catalytic triad [active]
765964000481	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
765964000482	Colicin V production protein; Region: Colicin_V; pfam02674
765964000483	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
765964000484	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
765964000485	dimer interface [polypeptide binding]; other site
765964000486	putative anticodon binding site; other site
765964000487	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
765964000488	motif 1; other site
765964000489	active site
765964000490	motif 2; other site
765964000491	motif 3; other site
765964000492	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
765964000493	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
765964000494	dimer interface [polypeptide binding]; other site
765964000495	active site
765964000496	glycine-pyridoxal phosphate binding site [chemical binding]; other site
765964000497	folate binding site [chemical binding]; other site
765964000498	Domain of unknown function (DUF1882); Region: DUF1882; pfam08966
765964000499	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
765964000500	Protein of unknown function DUF262; Region: DUF262; pfam03235
765964000501	Uncharacterized protein family, UPF0114; Region: UPF0114; cl01078
765964000502	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
765964000503	putative active site [active]
765964000504	catalytic site [active]
765964000505	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
765964000506	PLD-like domain; Region: PLDc_2; pfam13091
765964000507	putative active site [active]
765964000508	catalytic site [active]
765964000509	fumarate reductase iron-sulfur subunit; Provisional; Region: frdB; PRK13552
765964000510	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
765964000511	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
765964000512	fumarate reductase flavoprotein subunit; Provisional; Region: PRK08626
765964000513	L-aspartate oxidase; Provisional; Region: PRK06175
765964000514	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
765964000515	fumarate reductase cytochrome b-556 subunit; Provisional; Region: PRK13553
765964000516	Quinol:fumarate reductase (QFR) Type B subfamily, transmembrane subunit;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinone...; Region: QFR_TypeB_TM; cd00581
765964000517	Iron-sulfur protein interface; other site
765964000518	proximal heme binding site [chemical binding]; other site
765964000519	distal heme binding site [chemical binding]; other site
765964000520	dimer interface [polypeptide binding]; other site
765964000521	triosephosphate isomerase; Provisional; Region: PRK14567
765964000522	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
765964000523	substrate binding site [chemical binding]; other site
765964000524	dimer interface [polypeptide binding]; other site
765964000525	catalytic triad [active]
765964000526	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08415
765964000527	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
765964000528	NAD binding site [chemical binding]; other site
765964000529	homotetramer interface [polypeptide binding]; other site
765964000530	homodimer interface [polypeptide binding]; other site
765964000531	substrate binding site [chemical binding]; other site
765964000532	active site
765964000533	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
765964000534	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
765964000535	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
765964000536	trimer interface [polypeptide binding]; other site
765964000537	active site
765964000538	UDP-GlcNAc binding site [chemical binding]; other site
765964000539	lipid binding site [chemical binding]; lipid-binding site
765964000540	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
765964000541	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
765964000542	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
765964000543	DEAD-like helicases superfamily; Region: DEXDc; smart00487
765964000544	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
765964000545	Protein of unknown function (DUF4043); Region: DUF4043; pfam13252
765964000546	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
765964000547	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
765964000548	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
765964000549	phosphodiesterase; Provisional; Region: PRK12704
765964000550	CHC2 zinc finger; Region: zf-CHC2; pfam01807
765964000551	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
765964000552	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
765964000553	active site
765964000554	metal binding site [ion binding]; metal-binding site
765964000555	interdomain interaction site; other site
765964000556	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
765964000557	Walker A motif; other site
765964000558	ATP binding site [chemical binding]; other site
765964000559	Walker B motif; other site
765964000560	Helix-turn-helix domain; Region: HTH_36; pfam13730
765964000561	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
765964000562	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
765964000563	Int/Topo IB signature motif; other site
765964000564	S-adenosylmethionine synthetase; Validated; Region: PRK05250
765964000565	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
765964000566	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
765964000567	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
765964000568	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
765964000569	active site
765964000570	multimer interface [polypeptide binding]; other site
765964000571	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
765964000572	fatty acid/phospholipid synthesis protein PlsX; Region: plsX; TIGR00182
765964000573	3-oxoacyl-(acyl-carrier-protein) synthase III; Region: fabH; TIGR00747
765964000574	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
765964000575	dimer interface [polypeptide binding]; other site
765964000576	active site
765964000577	CoA binding pocket [chemical binding]; other site
765964000578	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
765964000579	Walker A/P-loop; other site
765964000580	ATP binding site [chemical binding]; other site
765964000581	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
765964000582	Walker B; other site
765964000583	D-loop; other site
765964000584	H-loop/switch region; other site
765964000585	antiporter inner membrane protein; Provisional; Region: PRK11670
765964000586	Domain of unknown function DUF59; Region: DUF59; pfam01883
765964000587	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
765964000588	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
765964000589	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
765964000590	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
765964000591	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
765964000592	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
765964000593	Toprim-like; Region: Toprim_2; pfam13155
765964000594	Type IV secretory pathway, VirB4 components [Intracellular trafficking and secretion]; Region: VirB4; COG3451
765964000595	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
765964000596	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
765964000597	Domain of unknown function DUF87; Region: DUF87; pfam01935
765964000598	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
765964000599	Topoisomerase IA [DNA replication, recombination, and repair]; Region: TopA; COG0550
765964000600	TOPRIM_TopoIA: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in the type IA family of DNA topoisomerases (TopoIA). This subgroup contains proteins similar to the Type I DNA topoisomerases: E. coli...; Region: TOPRIM_TopoIA; cd01028
765964000601	active site
765964000602	interdomain interaction site; other site
765964000603	putative metal-binding site [ion binding]; other site
765964000604	nucleotide binding site [chemical binding]; other site
765964000605	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cl11986
765964000606	domain I; other site
765964000607	DNA binding groove [nucleotide binding]
765964000608	phosphate binding site [ion binding]; other site
765964000609	domain II; other site
765964000610	domain III; other site
765964000611	nucleotide binding site [chemical binding]; other site
765964000612	catalytic site [active]
765964000613	domain IV; other site
765964000614	VirB8 protein; Region: VirB8; cl01500
765964000615	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
765964000616	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
765964000617	VirB7 interaction site; other site
765964000618	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
765964000619	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
765964000620	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
765964000621	Walker A motif; other site
765964000622	ATP binding site [chemical binding]; other site
765964000623	Walker B motif; other site
765964000624	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
765964000625	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
765964000626	Walker A motif; other site
765964000627	ATP binding site [chemical binding]; other site
765964000628	Walker B motif; other site
765964000629	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
765964000630	Type IV secretory pathway, VirD2 components (relaxase) [Intracellular trafficking and secretion]; Region: VirD2; COG3843
765964000631	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
765964000632	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
765964000633	P-loop; other site
765964000634	Magnesium ion binding site [ion binding]; other site
765964000635	potential frameshift: common BLAST hit: gi|210134644|ref|YP_002301083.1| DNA methylase
765964000636	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
765964000637	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
765964000638	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
765964000639	active site
765964000640	DNA binding site [nucleotide binding]
765964000641	Int/Topo IB signature motif; other site
765964000642	heat shock protein 90; Provisional; Region: PRK05218
765964000643	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
765964000644	ATP binding site [chemical binding]; other site
765964000645	Mg2+ binding site [ion binding]; other site
765964000646	G-X-G motif; other site
765964000647	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
765964000648	Sel1-like repeats; Region: SEL1; smart00671
765964000649	Sel1-like repeats; Region: SEL1; smart00671
765964000650	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
765964000651	TPR motif; other site
765964000652	binding surface
765964000653	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
765964000654	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
765964000655	metal binding site [ion binding]; metal-binding site
765964000656	dimer interface [polypeptide binding]; other site
765964000657	glucose-inhibited division protein A; Region: gidA; TIGR00136
765964000658	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
765964000659	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
765964000660	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
765964000661	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
765964000662	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
765964000663	transmembrane helices; other site
765964000664	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
765964000665	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
765964000666	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: Dxr; TIGR00243
765964000667	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
765964000668	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
765964000669	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
765964000670	potential frameshift: common BLAST hit: gi|210134418|ref|YP_002300857.1| beta-1,4-N-acetylgalactosamyltransferase
765964000671	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
765964000672	substrate binding site [chemical binding]; other site
765964000673	Helix-turn-helix domain; Region: HTH_28; pfam13518
765964000674	cysteine desulfurase, NifS family, epsilon proteobacteria type; Region: nifS_epsilon; TIGR03403
765964000675	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
765964000676	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
765964000677	catalytic residue [active]
765964000678	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
765964000679	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
765964000680	trimerization site [polypeptide binding]; other site
765964000681	active site
765964000682	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
765964000683	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
765964000684	DNA repair protein RadA; Region: sms; TIGR00416
765964000685	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
765964000686	Walker A motif/ATP binding site; other site
765964000687	ATP binding site [chemical binding]; other site
765964000688	Walker B motif; other site
765964000689	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
765964000690	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
765964000691	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
765964000692	SelR domain; Region: SelR; pfam01641
765964000693	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
765964000694	Predicted permeases [General function prediction only]; Region: COG0730
765964000695	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964000696	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
765964000697	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
765964000698	Sulfate transporter family; Region: Sulfate_transp; pfam00916
765964000699	potential protein location (hypothetical protein HPCU_01465 [Helicobacter pylori Cuz20]) that overlaps RNA (tRNA-N)
765964000700	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964000701	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
765964000702	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
765964000703	Ligand binding site; other site
765964000704	oligomer interface; other site
765964000705	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
765964000706	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
765964000707	hypothetical protein; Provisional; Region: PRK04081
765964000708	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
765964000709	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3295
765964000710	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
765964000711	Sel1-like repeats; Region: SEL1; smart00671
765964000712	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
765964000713	binding surface
765964000714	TPR motif; other site
765964000715	Sel1-like repeats; Region: SEL1; smart00671
765964000716	Sel1-like repeats; Region: SEL1; smart00671
765964000717	Cytochrome c; Region: Cytochrom_C; cl11414
765964000718	Porphobilinogen deaminase [Coenzyme metabolism]; Region: HemC; COG0181
765964000719	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
765964000720	domain interfaces; other site
765964000721	active site
765964000722	prolyl-tRNA synthetase, family II; Region: proS_fam_II; TIGR00409
765964000723	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
765964000724	dimer interface [polypeptide binding]; other site
765964000725	motif 1; other site
765964000726	active site
765964000727	motif 2; other site
765964000728	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
765964000729	putative deacylase active site [active]
765964000730	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
765964000731	active site
765964000732	motif 3; other site
765964000733	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
765964000734	anticodon binding site; other site
765964000735	glutamyl-tRNA reductase; Region: hemA; TIGR01035
765964000736	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
765964000737	tRNA; other site
765964000738	putative tRNA binding site [nucleotide binding]; other site
765964000739	putative NADP binding site [chemical binding]; other site
765964000740	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
765964000741	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
765964000742	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
765964000743	substrate binding pocket [chemical binding]; other site
765964000744	chain length determination region; other site
765964000745	substrate-Mg2+ binding site; other site
765964000746	catalytic residues [active]
765964000747	aspartate-rich region 1; other site
765964000748	active site lid residues [active]
765964000749	aspartate-rich region 2; other site
765964000750	Domain of unknown function (DUF2018); Region: DUF2018; pfam09442
765964000751	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
765964000752	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
765964000753	dimerization interface [polypeptide binding]; other site
765964000754	DPS ferroxidase diiron center [ion binding]; other site
765964000755	ion pore; other site
765964000756	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
765964000757	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
765964000758	dimer interface [polypeptide binding]; other site
765964000759	phosphorylation site [posttranslational modification]
765964000760	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
765964000761	ATP binding site [chemical binding]; other site
765964000762	Mg2+ binding site [ion binding]; other site
765964000763	G-X-G motif; other site
765964000764	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
765964000765	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
765964000766	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
765964000767	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
765964000768	ATP binding site [chemical binding]; other site
765964000769	Mg++ binding site [ion binding]; other site
765964000770	motif III; other site
765964000771	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
765964000772	nucleotide binding region [chemical binding]; other site
765964000773	ATP-binding site [chemical binding]; other site
765964000774	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
765964000775	SPFH domain / Band 7 family; Region: Band_7; pfam01145
765964000776	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
765964000777	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
765964000778	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
765964000779	Walker A/P-loop; other site
765964000780	ATP binding site [chemical binding]; other site
765964000781	Q-loop/lid; other site
765964000782	ABC transporter signature motif; other site
765964000783	Walker B; other site
765964000784	D-loop; other site
765964000785	H-loop/switch region; other site
765964000786	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
765964000787	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
765964000788	Walker A/P-loop; other site
765964000789	ATP binding site [chemical binding]; other site
765964000790	Q-loop/lid; other site
765964000791	ABC transporter signature motif; other site
765964000792	Walker B; other site
765964000793	D-loop; other site
765964000794	H-loop/switch region; other site
765964000795	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
765964000796	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
765964000797	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
765964000798	dimer interface [polypeptide binding]; other site
765964000799	conserved gate region; other site
765964000800	putative PBP binding loops; other site
765964000801	ABC-ATPase subunit interface; other site
765964000802	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964000803	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964000804	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
765964000805	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
765964000806	GDP-binding site [chemical binding]; other site
765964000807	ACT binding site; other site
765964000808	IMP binding site; other site
765964000809	Flagellar FliJ protein; Region: FliJ; pfam02050
765964000810	Uncharacterized conserved protein [Function unknown]; Region: COG3334
765964000811	RIP metalloprotease RseP; Region: TIGR00054
765964000812	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
765964000813	active site
765964000814	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
765964000815	protein binding site [polypeptide binding]; other site
765964000816	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
765964000817	putative substrate binding region [chemical binding]; other site
765964000818	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
765964000819	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
765964000820	generic binding surface II; other site
765964000821	generic binding surface I; other site
765964000822	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
765964000823	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964000824	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964000825	potential frameshift: common BLAST hit: gi|188527068|ref|YP_001909755.1| Endonuclease MjaVIP
765964000826	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
765964000827	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964000828	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
765964000829	Clp amino terminal domain; Region: Clp_N; pfam02861
765964000830	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964000831	Walker A motif; other site
765964000832	ATP binding site [chemical binding]; other site
765964000833	Walker B motif; other site
765964000834	arginine finger; other site
765964000835	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964000836	Walker A motif; other site
765964000837	ATP binding site [chemical binding]; other site
765964000838	Walker B motif; other site
765964000839	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
765964000840	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
765964000841	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
765964000842	Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; Region: PyrC; COG0044
765964000843	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
765964000844	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
765964000845	active site
765964000846	chlorohydrolase; Provisional; Region: PRK08418
765964000847	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_D; cd01312
765964000848	active site
765964000849	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
765964000850	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14339
765964000851	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
765964000852	FeS/SAM binding site; other site
765964000853	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
765964000854	putative acyl-acceptor binding pocket; other site
765964000855	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
765964000856	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
765964000857	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
765964000858	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
765964000859	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
765964000860	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
765964000861	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
765964000862	putative active site [active]
765964000863	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
765964000864	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
765964000865	putative acyl-acceptor binding pocket; other site
765964000866	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
765964000867	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
765964000868	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3400
765964000869	TrkA-C domain; Region: TrkA_C; pfam02080
765964000870	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
765964000871	active site
765964000872	dimer interface [polypeptide binding]; other site
765964000873	metal binding site [ion binding]; metal-binding site
765964000874	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
765964000875	Mechanosensitive ion channel; Region: MS_channel; pfam00924
765964000876	radical SAM methylthiotransferase, MiaB/RimO family; Region: TIGR00089
765964000877	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
765964000878	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
765964000879	FeS/SAM binding site; other site
765964000880	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
765964000881	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964000882	Walker A motif; other site
765964000883	ATP binding site [chemical binding]; other site
765964000884	Walker B motif; other site
765964000885	arginine finger; other site
765964000886	Domain of unknown function (DUF4149); Region: DUF4149; pfam13664
765964000887	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
765964000888	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
765964000889	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
765964000890	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
765964000891	Autotransporter beta-domain; Region: Autotransporter; pfam03797
765964000892	potential frameshift: common BLAST hit: gi|188527096|ref|YP_001909783.1| diaminopimelate decarboxylase
765964000893	Chorismate mutase [Amino acid transport and metabolism]; Region: PheA; COG1605
765964000894	Uncharacterized conserved protein [Function unknown]; Region: COG4866
765964000895	aminodeoxychorismate synthase; Provisional; Region: PRK07508
765964000896	chorismate binding enzyme; Region: Chorismate_bind; cl10555
765964000897	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
765964000898	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
765964000899	substrate-cofactor binding pocket; other site
765964000900	pyridoxal 5'-phosphate binding site [chemical binding]; other site
765964000901	catalytic residue [active]
765964000902	acylamide amidohydrolase; Provisional; Region: amiE; PRK13286
765964000903	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
765964000904	multimer interface [polypeptide binding]; other site
765964000905	active site
765964000906	catalytic triad [active]
765964000907	dimer interface [polypeptide binding]; other site
765964000908	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK08412
765964000909	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
765964000910	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
765964000911	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
765964000912	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
765964000913	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
765964000914	peptide binding site [polypeptide binding]; other site
765964000915	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
765964000916	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
765964000917	dimer interface [polypeptide binding]; other site
765964000918	conserved gate region; other site
765964000919	putative PBP binding loops; other site
765964000920	ABC-ATPase subunit interface; other site
765964000921	dipeptide transporter; Provisional; Region: PRK10913
765964000922	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
765964000923	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
765964000924	dimer interface [polypeptide binding]; other site
765964000925	conserved gate region; other site
765964000926	putative PBP binding loops; other site
765964000927	ABC-ATPase subunit interface; other site
765964000928	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
765964000929	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
765964000930	Walker A/P-loop; other site
765964000931	ATP binding site [chemical binding]; other site
765964000932	Q-loop/lid; other site
765964000933	ABC transporter signature motif; other site
765964000934	Walker B; other site
765964000935	D-loop; other site
765964000936	H-loop/switch region; other site
765964000937	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
765964000938	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
765964000939	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
765964000940	Walker A/P-loop; other site
765964000941	ATP binding site [chemical binding]; other site
765964000942	Q-loop/lid; other site
765964000943	ABC transporter signature motif; other site
765964000944	Walker B; other site
765964000945	D-loop; other site
765964000946	H-loop/switch region; other site
765964000947	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
765964000948	GTPase CgtA; Reviewed; Region: obgE; PRK12299
765964000949	GTP1/OBG; Region: GTP1_OBG; pfam01018
765964000950	Obg GTPase; Region: Obg; cd01898
765964000951	G1 box; other site
765964000952	GTP/Mg2+ binding site [chemical binding]; other site
765964000953	Switch I region; other site
765964000954	G2 box; other site
765964000955	G3 box; other site
765964000956	Switch II region; other site
765964000957	G4 box; other site
765964000958	G5 box; other site
765964000959	Alginate lyase; Region: Alginate_lyase; pfam05426
765964000960	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
765964000961	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
765964000962	inhibitor-cofactor binding pocket; inhibition site
765964000963	pyridoxal 5'-phosphate binding site [chemical binding]; other site
765964000964	catalytic residue [active]
765964000965	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
765964000966	Predicted amidohydrolase [General function prediction only]; Region: COG0388
765964000967	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
765964000968	active site
765964000969	catalytic triad [active]
765964000970	dimer interface [polypeptide binding]; other site
765964000971	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
765964000972	active site
765964000973	catalytic site [active]
765964000974	Zn binding site [ion binding]; other site
765964000975	tetramer interface [polypeptide binding]; other site
765964000976	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
765964000977	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
765964000978	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964000979	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
765964000980	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
765964000981	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
765964000982	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
765964000983	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
765964000984	putative substrate translocation pore; other site
765964000985	heme oxygenase, HugZ family; Region: heme_ox_HugZ; TIGR04109
765964000986	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
765964000987	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
765964000988	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
765964000989	arginyl-tRNA synthetase; Region: argS; TIGR00456
765964000990	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
765964000991	active site
765964000992	HIGH motif; other site
765964000993	KMSK motif region; other site
765964000994	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
765964000995	tRNA binding surface [nucleotide binding]; other site
765964000996	anticodon binding site; other site
765964000997	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
765964000998	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
765964000999	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
765964001000	catalytic site [active]
765964001001	G-X2-G-X-G-K; other site
765964001002	nuclease NucT; Provisional; Region: PRK13912
765964001003	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
765964001004	putative active site [active]
765964001005	catalytic site [active]
765964001006	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964001007	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
765964001008	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
765964001009	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
765964001010	ligand binding site; other site
765964001011	tetramer interface; other site
765964001012	Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: spsG; COG3980
765964001013	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
765964001014	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
765964001015	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
765964001016	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
765964001017	NAD synthetase; Provisional; Region: PRK13980
765964001018	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
765964001019	homodimer interface [polypeptide binding]; other site
765964001020	NAD binding pocket [chemical binding]; other site
765964001021	ATP binding pocket [chemical binding]; other site
765964001022	Mg binding site [ion binding]; other site
765964001023	active-site loop [active]
765964001024	ketol-acid reductoisomerase; Provisional; Region: PRK05479
765964001025	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
765964001026	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
765964001027	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
765964001028	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
765964001029	Switch I; other site
765964001030	Switch II; other site
765964001031	cell division topological specificity factor MinE; Region: minE; TIGR01215
765964001032	DNA protecting protein DprA; Region: dprA; TIGR00732
765964001033	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
765964001034	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
765964001035	Sel1-like repeats; Region: SEL1; smart00671
765964001036	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
765964001037	Sel1-like repeats; Region: SEL1; smart00671
765964001038	Sel1-like repeats; Region: SEL1; smart00671
765964001039	Sel1-like repeats; Region: SEL1; smart00671
765964001040	Sel1-like repeats; Region: SEL1; smart00671
765964001041	Sel1-like repeats; Region: SEL1; smart00671
765964001042	Sel1-like repeats; Region: SEL1; smart00671
765964001043	chlorohydrolase; Provisional; Region: PRK07213
765964001044	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
765964001045	catalytic residue [active]
765964001046	Predicted membrane protein [Function unknown]; Region: COG3326
765964001047	Phosphatidylinositol kinase and protein kinases of the PI-3 kinase family [Signal transduction mechanisms / Cell division and chromosome partitioning / Chromatin structure and dynamics / DNA replication, recombination, and repair / Intracellular...; Region: TEL1; COG5032
765964001048	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
765964001049	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
765964001050	active site
765964001051	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
765964001052	DHH family; Region: DHH; pfam01368
765964001053	DHHA1 domain; Region: DHHA1; pfam02272
765964001054	CTP synthetase; Validated; Region: pyrG; PRK05380
765964001055	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
765964001056	Catalytic site [active]
765964001057	active site
765964001058	UTP binding site [chemical binding]; other site
765964001059	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
765964001060	active site
765964001061	putative oxyanion hole; other site
765964001062	catalytic triad [active]
765964001063	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
765964001064	active site
765964001065	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
765964001066	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
765964001067	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
765964001068	flagellar motor switch protein FliG; Region: fliG; TIGR00207
765964001069	FliG C-terminal domain; Region: FliG_C; pfam01706
765964001070	flagellar assembly protein H; Validated; Region: fliH; PRK06669
765964001071	Flagellar assembly protein FliH; Region: FliH; pfam02108
765964001072	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
765964001073	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
765964001074	TPP-binding site; other site
765964001075	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
765964001076	PYR/PP interface [polypeptide binding]; other site
765964001077	dimer interface [polypeptide binding]; other site
765964001078	TPP binding site [chemical binding]; other site
765964001079	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
765964001080	GTP-binding protein LepA; Provisional; Region: PRK05433
765964001081	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
765964001082	G1 box; other site
765964001083	putative GEF interaction site [polypeptide binding]; other site
765964001084	GTP/Mg2+ binding site [chemical binding]; other site
765964001085	Switch I region; other site
765964001086	G2 box; other site
765964001087	G3 box; other site
765964001088	Switch II region; other site
765964001089	G4 box; other site
765964001090	G5 box; other site
765964001091	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
765964001092	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
765964001093	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
765964001094	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
765964001095	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
765964001096	cofactor binding site; other site
765964001097	DNA binding site [nucleotide binding]
765964001098	substrate interaction site [chemical binding]; other site
765964001099	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
765964001100	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
765964001101	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
765964001102	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
765964001103	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
765964001104	putative substrate translocation pore; other site
765964001105	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
765964001106	TspO/MBR family; Region: TspO_MBR; cl01379
765964001107	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
765964001108	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
765964001109	Inactivated superfamily I helicase [DNA replication, recombination, and repair]; Region: COG3893
765964001110	RecB family exonuclease [DNA replication, recombination, and repair]; Region: COG2887
765964001111	transketolase, bacterial and yeast; Region: tktlase_bact; TIGR00232
765964001112	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
765964001113	TPP-binding site [chemical binding]; other site
765964001114	dimer interface [polypeptide binding]; other site
765964001115	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
765964001116	PYR/PP interface [polypeptide binding]; other site
765964001117	dimer interface [polypeptide binding]; other site
765964001118	TPP binding site [chemical binding]; other site
765964001119	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
765964001120	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
765964001121	riboflavin kinase/FMN adenylyltransferase; Region: ribF; TIGR00083
765964001122	active site
765964001123	Riboflavin kinase; Region: Flavokinase; smart00904
765964001124	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
765964001125	hemolysin TlyA family protein; Region: tly; TIGR00478
765964001126	RNA binding surface [nucleotide binding]; other site
765964001127	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
765964001128	S-adenosylmethionine binding site [chemical binding]; other site
765964001129	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
765964001130	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
765964001131	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
765964001132	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
765964001133	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
765964001134	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
765964001135	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
765964001136	Walker A/P-loop; other site
765964001137	ATP binding site [chemical binding]; other site
765964001138	Q-loop/lid; other site
765964001139	ABC transporter signature motif; other site
765964001140	Walker B; other site
765964001141	D-loop; other site
765964001142	H-loop/switch region; other site
765964001143	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
765964001144	Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes [Defense mechanisms]; Region: COG1787
765964001145	Restriction endonuclease; Region: Mrr_cat; pfam04471
765964001146	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
765964001147	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cd00596
765964001148	active site
765964001149	Zn binding site [ion binding]; other site
765964001150	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
765964001151	metal-binding site [ion binding]
765964001152	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
765964001153	metal-binding site [ion binding]
765964001154	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
765964001155	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
765964001156	Soluble P-type ATPase [General function prediction only]; Region: COG4087
765964001157	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
765964001158	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
765964001159	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
765964001160	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964001161	Walker A motif; other site
765964001162	ATP binding site [chemical binding]; other site
765964001163	Walker B motif; other site
765964001164	arginine finger; other site
765964001165	Peptidase family M41; Region: Peptidase_M41; pfam01434
765964001166	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
765964001167	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
765964001168	S-adenosylmethionine binding site [chemical binding]; other site
765964001169	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
765964001170	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
765964001171	active site
765964001172	phosphorylation site [posttranslational modification]
765964001173	intermolecular recognition site; other site
765964001174	dimerization interface [polypeptide binding]; other site
765964001175	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964001176	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
765964001177	16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Region: gidB; TIGR00138
765964001178	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
765964001179	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
765964001180	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
765964001181	sec-independent translocase; Provisional; Region: PRK04098
765964001182	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
765964001183	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
765964001184	cofactor binding site; other site
765964001185	DNA binding site [nucleotide binding]
765964001186	substrate interaction site [chemical binding]; other site
765964001187	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
765964001188	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964001189	Walker A motif; other site
765964001190	ATP binding site [chemical binding]; other site
765964001191	Walker B motif; other site
765964001192	arginine finger; other site
765964001193	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
765964001194	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
765964001195	oligomerization interface [polypeptide binding]; other site
765964001196	active site
765964001197	metal binding site [ion binding]; metal-binding site
765964001198	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964001199	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964001200	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
765964001201	septum formation inhibitor; Reviewed; Region: minC; PRK00556
765964001202	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
765964001203	UDP-3-0-acyl N-acetylglucosamine deacetylase; Region: lpxC; TIGR00325
765964001204	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
765964001205	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
765964001206	homoserine kinase; Region: thrB; TIGR00191
765964001207	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
765964001208	Predicted nucleic-acid-binding protein implicated in transcription termination [Transcription]; Region: COG2740
765964001209	putative RNA binding cleft [nucleotide binding]; other site
765964001210	translation initiation factor IF-2; Region: IF-2; TIGR00487
765964001211	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
765964001212	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
765964001213	G1 box; other site
765964001214	putative GEF interaction site [polypeptide binding]; other site
765964001215	GTP/Mg2+ binding site [chemical binding]; other site
765964001216	Switch I region; other site
765964001217	G2 box; other site
765964001218	G3 box; other site
765964001219	Switch II region; other site
765964001220	G4 box; other site
765964001221	G5 box; other site
765964001222	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
765964001223	Translation-initiation factor 2; Region: IF-2; pfam11987
765964001224	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
765964001225	Ribosome-binding factor A; Region: RBFA; cl00542
765964001226	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
765964001227	Sm and related proteins; Region: Sm_like; cl00259
765964001228	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
765964001229	putative oligomer interface [polypeptide binding]; other site
765964001230	putative RNA binding site [nucleotide binding]; other site
765964001231	acetyl-CoA synthetase; Provisional; Region: PRK00174
765964001232	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
765964001233	active site
765964001234	CoA binding site [chemical binding]; other site
765964001235	acyl-activating enzyme (AAE) consensus motif; other site
765964001236	AMP binding site [chemical binding]; other site
765964001237	acetate binding site [chemical binding]; other site
765964001238	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
765964001239	putative active site [active]
765964001240	putative metal binding site [ion binding]; other site
765964001241	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
765964001242	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
765964001243	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
765964001244	active site
765964001245	intermolecular recognition site; other site
765964001246	dimerization interface [polypeptide binding]; other site
765964001247	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
765964001248	DNA binding site [nucleotide binding]
765964001249	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
765964001250	DHH family; Region: DHH; pfam01368
765964001251	flagellar biosynthesis protein FlhA; Region: FlhA; TIGR01398
765964001252	FHIPEP family; Region: FHIPEP; pfam00771
765964001253	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
765964001254	16S/18S rRNA binding site [nucleotide binding]; other site
765964001255	S13e-L30e interaction site [polypeptide binding]; other site
765964001256	25S rRNA binding site [nucleotide binding]; other site
765964001257	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
765964001258	O-Antigen ligase; Region: Wzy_C; pfam04932
765964001259	Dehydroquinase class II; Region: DHquinase_II; pfam01220
765964001260	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
765964001261	trimer interface [polypeptide binding]; other site
765964001262	active site
765964001263	dimer interface [polypeptide binding]; other site
765964001264	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
765964001265	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
765964001266	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
765964001267	active site
765964001268	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
765964001269	catalytic center binding site [active]
765964001270	ATP binding site [chemical binding]; other site
765964001271	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
765964001272	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
765964001273	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
765964001274	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
765964001275	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
765964001276	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
765964001277	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
765964001278	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
765964001279	DNA binding residues [nucleotide binding]
765964001280	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
765964001281	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
765964001282	flagellar motor switch protein FliY; Validated; Region: PRK08432
765964001283	flagellar motor switch protein FliN; Region: fliN; TIGR02480
765964001284	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
765964001285	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4731
765964001286	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
765964001287	metal binding site 2 [ion binding]; metal-binding site
765964001288	putative DNA binding helix; other site
765964001289	metal binding site 1 [ion binding]; metal-binding site
765964001290	dimer interface [polypeptide binding]; other site
765964001291	structural Zn2+ binding site [ion binding]; other site
765964001292	ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; Region: MGS1; COG2256
765964001293	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964001294	Walker A motif; other site
765964001295	ATP binding site [chemical binding]; other site
765964001296	Walker B motif; other site
765964001297	arginine finger; other site
765964001298	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
765964001299	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
765964001300	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
765964001301	DNA binding residues [nucleotide binding]
765964001302	putative dimer interface [polypeptide binding]; other site
765964001303	chaperone protein DnaJ; Provisional; Region: PRK14299
765964001304	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
765964001305	HSP70 interaction site [polypeptide binding]; other site
765964001306	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
765964001307	substrate binding site [polypeptide binding]; other site
765964001308	dimer interface [polypeptide binding]; other site
765964001309	5'-3' exonuclease; Provisional; Region: PRK14976
765964001310	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
765964001311	putative active site [active]
765964001312	Helix-hairpin-helix class 2 (Pol1 family) motifs; Region: HhH2; smart00279
765964001313	DNA binding site [nucleotide binding]
765964001314	metal binding site [ion binding]; metal-binding site
765964001315	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
765964001316	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
765964001317	active site
765964001318	dimerization interface [polypeptide binding]; other site
765964001319	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
765964001320	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
765964001321	substrate binding site; other site
765964001322	dimer interface; other site
765964001323	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
765964001324	homotrimer interaction site [polypeptide binding]; other site
765964001325	zinc binding site [ion binding]; other site
765964001326	CDP-binding sites; other site
765964001327	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
765964001328	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
765964001329	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
765964001330	protein binding site [polypeptide binding]; other site
765964001331	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
765964001332	protein binding site [polypeptide binding]; other site
765964001333	S-methylmethionine transporter; Provisional; Region: PRK11387
765964001334	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Region: pgsA; TIGR00560
765964001335	7-alpha-hydroxysteroid dehydrogenase; Provisional; Region: PRK08416
765964001336	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
765964001337	putative NAD(P) binding site [chemical binding]; other site
765964001338	active site
765964001339	dihydrodipicolinate synthase; Region: dapA; TIGR00674
765964001340	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
765964001341	dimer interface [polypeptide binding]; other site
765964001342	active site
765964001343	catalytic residue [active]
765964001344	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
765964001345	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
765964001346	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
765964001347	dihydroorotate dehydrogenase, subfamily 2; Region: pyrD_sub2; TIGR01036
765964001348	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
765964001349	quinone interaction residues [chemical binding]; other site
765964001350	active site
765964001351	catalytic residues [active]
765964001352	FMN binding site [chemical binding]; other site
765964001353	substrate binding site [chemical binding]; other site
765964001354	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
765964001355	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
765964001356	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
765964001357	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
765964001358	putative domain interface [polypeptide binding]; other site
765964001359	putative active site [active]
765964001360	catalytic site [active]
765964001361	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
765964001362	putative active site [active]
765964001363	putative domain interface [polypeptide binding]; other site
765964001364	catalytic site [active]
765964001365	potential protein location (hypothetical protein HPCU_02525 [Helicobacter pylori Cuz20]) that overlaps RNA (tRNA-P)
765964001366	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
765964001367	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
765964001368	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
765964001369	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
765964001370	Methyltransferase domain; Region: Methyltransf_26; pfam13659
765964001371	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
765964001372	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
765964001373	ATP binding site [chemical binding]; other site
765964001374	putative Mg++ binding site [ion binding]; other site
765964001375	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
765964001376	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
765964001377	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
765964001378	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
765964001379	putative metal binding site [ion binding]; other site
765964001380	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
765964001381	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
765964001382	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
765964001383	active site
765964001384	Zn binding site [ion binding]; other site
765964001385	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
765964001386	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
765964001387	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964001388	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
765964001389	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
765964001390	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
765964001391	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
765964001392	dimer interface [polypeptide binding]; other site
765964001393	conserved gate region; other site
765964001394	putative PBP binding loops; other site
765964001395	ABC-ATPase subunit interface; other site
765964001396	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
765964001397	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
765964001398	Walker A/P-loop; other site
765964001399	ATP binding site [chemical binding]; other site
765964001400	Q-loop/lid; other site
765964001401	ABC transporter signature motif; other site
765964001402	Walker B; other site
765964001403	D-loop; other site
765964001404	H-loop/switch region; other site
765964001405	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
765964001406	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
765964001407	active site
765964001408	HIGH motif; other site
765964001409	nucleotide binding site [chemical binding]; other site
765964001410	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
765964001411	active site
765964001412	KMSKS motif; other site
765964001413	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964001414	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
765964001415	Methyltransferase domain; Region: Methyltransf_26; pfam13659
765964001416	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
765964001417	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
765964001418	ADP-heptose:LPS heptosyl transferase I; Provisional; Region: PRK10964; cl15782
765964001419	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
765964001420	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
765964001421	G1 box; other site
765964001422	putative GEF interaction site [polypeptide binding]; other site
765964001423	GTP/Mg2+ binding site [chemical binding]; other site
765964001424	Switch I region; other site
765964001425	G2 box; other site
765964001426	G3 box; other site
765964001427	Switch II region; other site
765964001428	G4 box; other site
765964001429	G5 box; other site
765964001430	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
765964001431	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
765964001432	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
765964001433	Catalytic GIY-YIG domain of coliphage T4 non-specific endonuclease II, type II restriction endonuclease R.Hpy188I, and similar proteins; Region: GIY-YIG_EndoII_Hpy188I_like; cd10436
765964001434	GIY-YIG motif/motif A; other site
765964001435	DNA binding site [nucleotide binding]
765964001436	active site
765964001437	catalytic site [active]
765964001438	metal binding site [ion binding]; metal-binding site
765964001439	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
765964001440	Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153
765964001441	putative heme binding pocket [chemical binding]; other site
765964001442	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
765964001443	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
765964001444	Cation transport protein; Region: TrkH; cl17365
765964001445	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
765964001446	TrkA-N domain; Region: TrkA_N; pfam02254
765964001447	TrkA-C domain; Region: TrkA_C; pfam02080
765964001448	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
765964001449	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
765964001450	phospho-N-acetylmuramoyl-pentapeptide-transferase; Region: mraY; TIGR00445
765964001451	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
765964001452	Mg++ binding site [ion binding]; other site
765964001453	putative catalytic motif [active]
765964001454	putative substrate binding site [chemical binding]; other site
765964001455	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03815
765964001456	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
765964001457	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
765964001458	Protein of unknown function (DUF493); Region: DUF493; pfam04359
765964001459	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
765964001460	active site
765964001461	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
765964001462	Na2 binding site [ion binding]; other site
765964001463	putative substrate binding site 1 [chemical binding]; other site
765964001464	Na binding site 1 [ion binding]; other site
765964001465	putative substrate binding site 2 [chemical binding]; other site
765964001466	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
765964001467	Na2 binding site [ion binding]; other site
765964001468	putative substrate binding site 1 [chemical binding]; other site
765964001469	Na binding site 1 [ion binding]; other site
765964001470	putative substrate binding site 2 [chemical binding]; other site
765964001471	potential frameshift: common BLAST hit: gi|188527662|ref|YP_001910349.1| phospholipase A1
765964001472	DNA polymerase III, beta subunit; Region: dnan; TIGR00663
765964001473	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
765964001474	putative DNA binding surface [nucleotide binding]; other site
765964001475	dimer interface [polypeptide binding]; other site
765964001476	beta-clamp/translesion DNA polymerase binding surface; other site
765964001477	beta-clamp/clamp loader binding surface; other site
765964001478	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
765964001479	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
765964001480	Mg2+ binding site [ion binding]; other site
765964001481	G-X-G motif; other site
765964001482	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
765964001483	anchoring element; other site
765964001484	dimer interface [polypeptide binding]; other site
765964001485	ATP binding site [chemical binding]; other site
765964001486	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
765964001487	active site
765964001488	putative metal-binding site [ion binding]; other site
765964001489	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
765964001490	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
765964001491	Peptidase family M23; Region: Peptidase_M23; pfam01551
765964001492	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
765964001493	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
765964001494	dimer interface [polypeptide binding]; other site
765964001495	ADP-ribose binding site [chemical binding]; other site
765964001496	active site
765964001497	nudix motif; other site
765964001498	metal binding site [ion binding]; metal-binding site
765964001499	FAD binding domain; Region: FAD_binding_4; pfam01565
765964001500	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
765964001501	Protein-interacting Bro1-like domain of mammalian Alix and related domains; Region: BRO1_Alix_like; cl14649
765964001502	dihydrodipicolinate reductase; Region: dapB; TIGR00036
765964001503	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
765964001504	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
765964001505	glutamine synthetase, type I; Region: GlnA; TIGR00653
765964001506	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
765964001507	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
765964001508	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
765964001509	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
765964001510	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
765964001511	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
765964001512	active site
765964001513	HslU subunit interaction site [polypeptide binding]; other site
765964001514	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
765964001515	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964001516	Walker A motif; other site
765964001517	ATP binding site [chemical binding]; other site
765964001518	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964001519	Walker B motif; other site
765964001520	arginine finger; other site
765964001521	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
765964001522	GTPase [General function prediction only]; Region: Era; COG1159
765964001523	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
765964001524	G1 box; other site
765964001525	GTP/Mg2+ binding site [chemical binding]; other site
765964001526	Switch I region; other site
765964001527	G2 box; other site
765964001528	Switch II region; other site
765964001529	G3 box; other site
765964001530	G4 box; other site
765964001531	G5 box; other site
765964001532	KH domain; Region: KH_2; pfam07650
765964001533	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
765964001534	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
765964001535	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
765964001536	The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome. They contain an ATP binding domain. VirD4 is involved in DNA transfer...; Region: TraG_VirD4; cd01126
765964001537	Walker A motif; other site
765964001538	ATP binding site [chemical binding]; other site
765964001539	Walker B motif; other site
765964001540	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
765964001541	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
765964001542	ATP binding site [chemical binding]; other site
765964001543	Walker A motif; other site
765964001544	hexamer interface [polypeptide binding]; other site
765964001545	Walker B motif; other site
765964001546	CagZ; Region: CagZ; pfam09053
765964001547	DC-EC Repeat; Region: CagY_M; pfam07337
765964001548	DC-EC Repeat; Region: CagY_M; pfam07337
765964001549	DC-EC Repeat; Region: CagY_M; pfam07337
765964001550	DC-EC Repeat; Region: CagY_M; pfam07337
765964001551	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
765964001552	potential frameshift: common BLAST hit: gi|188527635|ref|YP_001910322.1| cag pathogenicity island protein (cagY, cag7)
765964001553	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
765964001554	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
765964001555	VirB7 interaction site; other site
765964001556	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
765964001557	Cag pathogenicity island protein Cag12; Region: Cag12; pfam13117
765964001558	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK06945
765964001559	prolyl-tRNA synthetase; Provisional; Region: PRK08661
765964001560	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
765964001561	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
765964001562	Transposase IS200 like; Region: Y1_Tnp; pfam01797
765964001563	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
765964001564	Probable transposase; Region: OrfB_IS605; pfam01385
765964001565	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
765964001566	CagA exotoxin; Region: CagA; pfam03507
765964001567	CagA exotoxin; Region: CagA; pfam03507
765964001568	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
765964001569	transcription termination factor Rho; Provisional; Region: rho; PRK09376
765964001570	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
765964001571	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
765964001572	RNA binding site [nucleotide binding]; other site
765964001573	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
765964001574	multimer interface [polypeptide binding]; other site
765964001575	Walker A motif; other site
765964001576	ATP binding site [chemical binding]; other site
765964001577	Walker B motif; other site
765964001578	Ribosomal protein L31; Region: Ribosomal_L31; pfam01197
765964001579	Predicted methyltransferases [General function prediction only]; Region: COG0313
765964001580	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
765964001581	putative SAM binding site [chemical binding]; other site
765964001582	putative homodimer interface [polypeptide binding]; other site
765964001583	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
765964001584	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
765964001585	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
765964001586	acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Region: accA; TIGR00513
765964001587	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
765964001588	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK08439
765964001589	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
765964001590	dimer interface [polypeptide binding]; other site
765964001591	active site
765964001592	acyl carrier protein; Provisional; Region: acpP; PRK00982
765964001593	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
765964001594	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
765964001595	NAD(P) binding site [chemical binding]; other site
765964001596	active site
765964001597	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
765964001598	Predicted membrane protein [Function unknown]; Region: COG3059
765964001599	diaminopimelate epimerase; Region: DapF; TIGR00652
765964001600	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
765964001601	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
765964001602	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
765964001603	Domain of unknown function DUF20; Region: UPF0118; pfam01594
765964001604	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
765964001605	GTP-binding protein YchF; Reviewed; Region: PRK09601
765964001606	YchF GTPase; Region: YchF; cd01900
765964001607	G1 box; other site
765964001608	GTP/Mg2+ binding site [chemical binding]; other site
765964001609	Switch I region; other site
765964001610	G2 box; other site
765964001611	Switch II region; other site
765964001612	G3 box; other site
765964001613	G4 box; other site
765964001614	G5 box; other site
765964001615	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
765964001616	multifunctional aminopeptidase A; Provisional; Region: PRK00913
765964001617	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
765964001618	interface (dimer of trimers) [polypeptide binding]; other site
765964001619	Substrate-binding/catalytic site; other site
765964001620	Zn-binding sites [ion binding]; other site
765964001621	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
765964001622	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
765964001623	active site
765964001624	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
765964001625	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
765964001626	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
765964001627	Peptidase family M50; Region: Peptidase_M50; pfam02163
765964001628	active site
765964001629	putative substrate binding region [chemical binding]; other site
765964001630	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
765964001631	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
765964001632	Catalytic site [active]
765964001633	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
765964001634	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14191
765964001635	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
765964001636	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
765964001637	homodimer interface [polypeptide binding]; other site
765964001638	NADP binding site [chemical binding]; other site
765964001639	substrate binding site [chemical binding]; other site
765964001640	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
765964001641	Sulfatase; Region: Sulfatase; pfam00884
765964001642	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
765964001643	BNR repeat-like domain; Region: BNR_2; pfam13088
765964001644	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
765964001645	active site
765964001646	substrate binding pocket [chemical binding]; other site
765964001647	dimer interface [polypeptide binding]; other site
765964001648	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
765964001649	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
765964001650	flagellar motor switch protein; Validated; Region: PRK08433
765964001651	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
765964001652	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
765964001653	minor groove reading motif; other site
765964001654	helix-hairpin-helix signature motif; other site
765964001655	substrate binding pocket [chemical binding]; other site
765964001656	active site
765964001657	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
765964001658	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
765964001659	Protein of unknown function; Region: DUF3971; pfam13116
765964001660	AsmA-like C-terminal region; Region: AsmA_1; pfam13109
765964001661	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
765964001662	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
765964001663	dimerization interface [polypeptide binding]; other site
765964001664	2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed; Region: oorD; PRK09626
765964001665	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
765964001666	2-oxoglutarate-acceptor oxidoreductase subunit OorA; Reviewed; Region: oorA; PRK09627
765964001667	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
765964001668	dimer interface [polypeptide binding]; other site
765964001669	PYR/PP interface [polypeptide binding]; other site
765964001670	TPP binding site [chemical binding]; other site
765964001671	substrate binding site [chemical binding]; other site
765964001672	2-oxoglutarate-acceptor oxidoreductase subunit OorB; Reviewed; Region: oorB; PRK09628
765964001673	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
765964001674	TPP-binding site [chemical binding]; other site
765964001675	2-oxoglutarate-acceptor oxidoreductase subunit OorC; Reviewed; Region: oorC; PRK08441
765964001676	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
765964001677	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
765964001678	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Region: HAD-SF-IA-v1; TIGR01549
765964001679	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
765964001680	tumor necrosis factor alpha-inducing protein; Reviewed; Region: PRK12303
765964001681	Transglycosylase; Region: Transgly; pfam00912
765964001682	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
765964001683	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
765964001684	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
765964001685	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
765964001686	catalytic residue [active]
765964001687	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
765964001688	dimer interface [polypeptide binding]; other site
765964001689	putative CheW interface [polypeptide binding]; other site
765964001690	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
765964001691	potential frameshift: common BLAST hit: gi|188527551|ref|YP_001910238.1| multidrug resistance protein (spaB)
765964001692	flagellin A; Reviewed; Region: PRK12584
765964001693	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
765964001694	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
765964001695	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
765964001696	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
765964001697	3-methyladenine DNA glycosylase; Provisional; Region: PRK13913
765964001698	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
765964001699	minor groove reading motif; other site
765964001700	helix-hairpin-helix signature motif; other site
765964001701	active site
765964001702	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
765964001703	substrate binding site [chemical binding]; other site
765964001704	active site
765964001705	Outer membrane efflux protein; Region: OEP; pfam02321
765964001706	Outer membrane efflux protein; Region: OEP; pfam02321
765964001707	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
765964001708	HlyD family secretion protein; Region: HlyD_3; pfam13437
765964001709	AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873
765964001710	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964001711	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
765964001712	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
765964001713	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
765964001714	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
765964001715	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
765964001716	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
765964001717	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
765964001718	Autotransporter beta-domain; Region: Autotransporter; pfam03797
765964001719	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
765964001720	Walker B; other site
765964001721	D-loop; other site
765964001722	H-loop/switch region; other site
765964001723	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
765964001724	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
765964001725	nucleotide binding pocket [chemical binding]; other site
765964001726	K-X-D-G motif; other site
765964001727	catalytic site [active]
765964001728	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
765964001729	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
765964001730	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
765964001731	Dimer interface [polypeptide binding]; other site
765964001732	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
765964001733	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
765964001734	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
765964001735	active site
765964001736	phosphorylation site [posttranslational modification]
765964001737	intermolecular recognition site; other site
765964001738	dimerization interface [polypeptide binding]; other site
765964001739	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
765964001740	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
765964001741	dimer interface [polypeptide binding]; other site
765964001742	anticodon binding site; other site
765964001743	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
765964001744	homodimer interface [polypeptide binding]; other site
765964001745	motif 1; other site
765964001746	active site
765964001747	motif 2; other site
765964001748	GAD domain; Region: GAD; pfam02938
765964001749	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
765964001750	active site
765964001751	motif 3; other site
765964001752	adenylate kinase; Reviewed; Region: adk; PRK00279
765964001753	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
765964001754	AMP-binding site [chemical binding]; other site
765964001755	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
765964001756	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
765964001757	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
765964001758	potential frameshift: common BLAST hit: gi|210134822|ref|YP_002301261.1| lipopolysaccharide biosynthesis protein
765964001759	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
765964001760	dimer interface [polypeptide binding]; other site
765964001761	substrate binding site [chemical binding]; other site
765964001762	metal binding sites [ion binding]; metal-binding site
765964001763	MutS2 family protein; Region: mutS2; TIGR01069
765964001764	ATPase domain of DNA mismatch repair MUTS family; Region: MUTSac; smart00534
765964001765	Walker A/P-loop; other site
765964001766	ATP binding site [chemical binding]; other site
765964001767	Q-loop/lid; other site
765964001768	ABC transporter signature motif; other site
765964001769	Walker B; other site
765964001770	D-loop; other site
765964001771	H-loop/switch region; other site
765964001772	Smr domain; Region: Smr; pfam01713
765964001773	UDP-N-acetylmuramate--alanine ligase; Region: murC; TIGR01082
765964001774	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
765964001775	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
765964001776	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
765964001777	hypothetical protein; Provisional; Region: PRK05839
765964001778	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
765964001779	pyridoxal 5'-phosphate binding site [chemical binding]; other site
765964001780	homodimer interface [polypeptide binding]; other site
765964001781	catalytic residue [active]
765964001782	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
765964001783	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
765964001784	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
765964001785	Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Region: DapD; COG2171
765964001786	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
765964001787	putative trimer interface [polypeptide binding]; other site
765964001788	putative CoA binding site [chemical binding]; other site
765964001789	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
765964001790	Sel1-like repeats; Region: SEL1; smart00671
765964001791	Sel1-like repeats; Region: SEL1; smart00671
765964001792	Sel1 repeat; Region: Sel1; cl02723
765964001793	Sel1-like repeats; Region: SEL1; smart00671
765964001794	Uncharacterized conserved protein [Function unknown]; Region: COG1479
765964001795	Protein of unknown function DUF262; Region: DUF262; pfam03235
765964001796	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
765964001797	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
765964001798	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
765964001799	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
765964001800	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
765964001801	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
765964001802	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
765964001803	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
765964001804	nickel binding site [ion binding]; other site
765964001805	putative substrate-binding site; other site
765964001806	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964001807	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
765964001808	Ligand Binding Site [chemical binding]; other site
765964001809	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
765964001810	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
765964001811	active site
765964001812	NTP binding site [chemical binding]; other site
765964001813	metal binding triad [ion binding]; metal-binding site
765964001814	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
765964001815	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
765964001816	dimer interface [polypeptide binding]; other site
765964001817	FMN binding site [chemical binding]; other site
765964001818	glutamylglutaminyl-tRNA synthetase; Provisional; Region: PRK12410
765964001819	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
765964001820	active site
765964001821	HIGH motif; other site
765964001822	nucleotide binding site [chemical binding]; other site
765964001823	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
765964001824	active site
765964001825	KMSKS motif; other site
765964001826	YGGT family; Region: YGGT; pfam02325
765964001827	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
765964001828	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
765964001829	N-acetyl-D-glucosamine binding site [chemical binding]; other site
765964001830	catalytic residue [active]
765964001831	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
765964001832	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
765964001833	active site
765964001834	tetramer interface; other site
765964001835	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
765964001836	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
765964001837	hinge; other site
765964001838	active site
765964001839	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
765964001840	Aspartase; Region: Aspartase; cd01357
765964001841	active sites [active]
765964001842	tetramer interface [polypeptide binding]; other site
765964001843	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
765964001844	ligand binding site [chemical binding]; other site
765964001845	active site
765964001846	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
765964001847	phosphoserine phosphatase SerB; Region: serB; TIGR00338
765964001848	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
765964001849	motif II; other site
765964001850	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
765964001851	Ferritin-like domain; Region: Ferritin; pfam00210
765964001852	ferroxidase diiron center [ion binding]; other site
765964001853	hypothetical protein; Provisional; Region: PRK08444
765964001854	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
765964001855	FeS/SAM binding site; other site
765964001856	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
765964001857	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
765964001858	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
765964001859	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
765964001860	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
765964001861	Surface antigen; Region: Bac_surface_Ag; pfam01103
765964001862	hypothetical protein; Provisional; Region: PRK08445
765964001863	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
765964001864	FeS/SAM binding site; other site
765964001865	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
765964001866	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
765964001867	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
765964001868	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
765964001869	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
765964001870	GatB domain; Region: GatB_Yqey; smart00845
765964001871	SurA N-terminal domain; Region: SurA_N; pfam09312
765964001872	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
765964001873	Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module [General function prediction only]; Region: COG1439
765964001874	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
765964001875	RNA/DNA hybrid binding site [nucleotide binding]; other site
765964001876	active site
765964001877	ribonuclease III; Reviewed; Region: rnc; PRK00102
765964001878	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
765964001879	dimerization interface [polypeptide binding]; other site
765964001880	active site
765964001881	metal binding site [ion binding]; metal-binding site
765964001882	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
765964001883	dsRNA binding site [nucleotide binding]; other site
765964001884	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
765964001885	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
765964001886	Tetramer interface [polypeptide binding]; other site
765964001887	active site
765964001888	FMN-binding site [chemical binding]; other site
765964001889	Protein of unknown function (DUF2603); Region: DUF2603; pfam10788
765964001890	oxygen-independent coproporphyrinogen III oxidase; Region: hemN; TIGR00538
765964001891	HemN C-terminal domain; Region: HemN_C; pfam06969
765964001892	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
765964001893	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
765964001894	Cysteine-rich domain; Region: CCG; pfam02754
765964001895	Cysteine-rich domain; Region: CCG; pfam02754
765964001896	Restriction endonuclease; Region: Mrr_cat_2; pfam13156
765964001897	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
765964001898	Predicted helicase [General function prediction only]; Region: COG4889
765964001899	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
765964001900	nucleotide binding region [chemical binding]; other site
765964001901	ATP-binding site [chemical binding]; other site
765964001902	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964001903	aspartate aminotransferase; Provisional; Region: PRK05764
765964001904	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
765964001905	pyridoxal 5'-phosphate binding site [chemical binding]; other site
765964001906	homodimer interface [polypeptide binding]; other site
765964001907	catalytic residue [active]
765964001908	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
765964001909	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
765964001910	active site
765964001911	DNA binding site [nucleotide binding]
765964001912	Int/Topo IB signature motif; other site
765964001913	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
765964001914	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
765964001915	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
765964001916	DNA binding site [nucleotide binding]
765964001917	active site
765964001918	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
765964001919	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
765964001920	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
765964001921	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
765964001922	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08447
765964001923	ATP cone domain; Region: ATP-cone; pfam03477
765964001924	Class I ribonucleotide reductase; Region: RNR_I; cd01679
765964001925	active site
765964001926	dimer interface [polypeptide binding]; other site
765964001927	catalytic residues [active]
765964001928	effector binding site; other site
765964001929	R2 peptide binding site; other site
765964001930	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14359
765964001931	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
765964001932	Substrate binding site; other site
765964001933	Mg++ binding site; other site
765964001934	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
765964001935	active site
765964001936	substrate binding site [chemical binding]; other site
765964001937	CoA binding site [chemical binding]; other site
765964001938	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
765964001939	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
765964001940	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
765964001941	N-terminal plug; other site
765964001942	ligand-binding site [chemical binding]; other site
765964001943	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
765964001944	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
765964001945	G1 box; other site
765964001946	GTP/Mg2+ binding site [chemical binding]; other site
765964001947	Switch I region; other site
765964001948	G2 box; other site
765964001949	G3 box; other site
765964001950	Switch II region; other site
765964001951	G4 box; other site
765964001952	G5 box; other site
765964001953	Nucleoside recognition; Region: Gate; pfam07670
765964001954	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
765964001955	Nucleoside recognition; Region: Gate; pfam07670
765964001956	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
765964001957	active site
765964001958	catalytic site [active]
765964001959	substrate binding site [chemical binding]; other site
765964001960	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108
765964001961	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
765964001962	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964001963	CfrBI restriction endonuclease; Region: RE_CfrBI; pfam09516
765964001964	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB [DNA replication, recombination, and repair]; Region: COG3298
765964001965	putative acyltransferase; Provisional; Region: PRK05790
765964001966	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
765964001967	dimer interface [polypeptide binding]; other site
765964001968	active site
765964001969	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
765964001970	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
765964001971	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
765964001972	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
765964001973	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
765964001974	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
765964001975	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
765964001976	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
765964001977	Hydantoinase B/oxoprolinase; Region: Hydantoinase_B; pfam02538
765964001978	Acetone carboxylase, gamma subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcxC; COG4647
765964001979	Acetone carboxylase gamma subunit; Region: Acetone_carb_G; pfam08882
765964001980	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
765964001981	DNA gyrase subunit A; Validated; Region: PRK05560
765964001982	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
765964001983	CAP-like domain; other site
765964001984	active site
765964001985	primary dimer interface [polypeptide binding]; other site
765964001986	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
765964001987	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
765964001988	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
765964001989	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
765964001990	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
765964001991	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
765964001992	Response regulator receiver domain; Region: Response_reg; pfam00072
765964001993	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
765964001994	active site
765964001995	phosphorylation site [posttranslational modification]
765964001996	intermolecular recognition site; other site
765964001997	dimerization interface [polypeptide binding]; other site
765964001998	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964001999	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
765964002000	Walker A motif; other site
765964002001	ATP binding site [chemical binding]; other site
765964002002	Walker B motif; other site
765964002003	arginine finger; other site
765964002004	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
765964002005	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
765964002006	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
765964002007	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
765964002008	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964002009	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
765964002010	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
765964002011	Uncharacterized conserved protein [Function unknown]; Region: COG1912
765964002012	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
765964002013	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
765964002014	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964002015	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
765964002016	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
765964002017	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
765964002018	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
765964002019	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
765964002020	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
765964002021	Walker A/P-loop; other site
765964002022	ATP binding site [chemical binding]; other site
765964002023	Q-loop/lid; other site
765964002024	ABC transporter signature motif; other site
765964002025	Walker B; other site
765964002026	D-loop; other site
765964002027	H-loop/switch region; other site
765964002028	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
765964002029	DNA polymerase III subunits gamma and tau; Validated; Region: PRK08451
765964002030	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964002031	Walker A motif; other site
765964002032	ATP binding site [chemical binding]; other site
765964002033	Walker B motif; other site
765964002034	arginine finger; other site
765964002035	Lysine efflux permease [General function prediction only]; Region: COG1279
765964002036	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
765964002037	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
765964002038	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
765964002039	active site
765964002040	homotetramer interface [polypeptide binding]; other site
765964002041	homodimer interface [polypeptide binding]; other site
765964002042	anaerobic c4-dicarboxylate membrane transporter family protein; Region: Dcu; TIGR00770
765964002043	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
765964002044	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964002045	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
765964002046	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
765964002047	FMN binding site [chemical binding]; other site
765964002048	active site
765964002049	catalytic residues [active]
765964002050	substrate binding site [chemical binding]; other site
765964002051	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
765964002052	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
765964002053	Ligand Binding Site [chemical binding]; other site
765964002054	MiaB-like tRNA modifying enzyme, archaeal-type; Region: MiaB-like-B; TIGR01578
765964002055	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
765964002056	G1 box; other site
765964002057	GTP/Mg2+ binding site [chemical binding]; other site
765964002058	G2 box; other site
765964002059	Switch I region; other site
765964002060	G3 box; other site
765964002061	Switch II region; other site
765964002062	G4 box; other site
765964002063	AAA domain; Region: AAA_23; pfam13476
765964002064	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
765964002065	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
765964002066	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
765964002067	FeS/SAM binding site; other site
765964002068	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236
765964002069	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
765964002070	active site
765964002071	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
765964002072	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
765964002073	catalytic residue [active]
765964002074	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
765964002075	tetramer interfaces [polypeptide binding]; other site
765964002076	binuclear metal-binding site [ion binding]; other site
765964002077	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
765964002078	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
765964002079	ATP-grasp domain; Region: ATP-grasp_4; cl17255
765964002080	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
765964002081	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
765964002082	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
765964002083	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
765964002084	nucleotide binding site/active site [active]
765964002085	HIT family signature motif; other site
765964002086	catalytic residue [active]
765964002087	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
765964002088	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
765964002089	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
765964002090	active site
765964002091	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
765964002092	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
765964002093	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
765964002094	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
765964002095	G1 box; other site
765964002096	G1 box; other site
765964002097	GTP/Mg2+ binding site [chemical binding]; other site
765964002098	GTP/Mg2+ binding site [chemical binding]; other site
765964002099	G2 box; other site
765964002100	Switch I region; other site
765964002101	G3 box; other site
765964002102	Switch II region; other site
765964002103	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
765964002104	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
765964002105	active site
765964002106	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
765964002107	Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401
765964002108	Interdomain contacts; other site
765964002109	Cytokine receptor motif; other site
765964002110	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
765964002111	Interdomain contacts; other site
765964002112	Cytokine receptor motif; other site
765964002113	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
765964002114	Interdomain contacts; other site
765964002115	Cytokine receptor motif; other site
765964002116	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
765964002117	S-adenosylmethionine binding site [chemical binding]; other site
765964002118	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
765964002119	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
765964002120	Walker A/P-loop; other site
765964002121	ATP binding site [chemical binding]; other site
765964002122	Q-loop/lid; other site
765964002123	ABC transporter signature motif; other site
765964002124	Walker B; other site
765964002125	D-loop; other site
765964002126	H-loop/switch region; other site
765964002127	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
765964002128	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
765964002129	Peptidase family M23; Region: Peptidase_M23; pfam01551
765964002130	flagellar protein FlaG; Provisional; Region: PRK08452
765964002131	flagellar capping protein; Validated; Region: fliD; PRK08453
765964002132	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
765964002133	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
765964002134	flagellar biosynthetic protein FliS; Region: fliS; TIGR00208
765964002135	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
765964002136	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
765964002137	putative ATP binding site [chemical binding]; other site
765964002138	putative substrate interface [chemical binding]; other site
765964002139	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
765964002140	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
765964002141	putative active site; other site
765964002142	catalytic triad [active]
765964002143	putative dimer interface [polypeptide binding]; other site
765964002144	Predicted permease [General function prediction only]; Region: COG2056
765964002145	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
765964002146	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
765964002147	putative efflux protein, MATE family; Region: matE; TIGR00797
765964002148	phosphodiesterase; Provisional; Region: PRK12704
765964002149	K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; Region: KH-I; cd00105
765964002150	nucleic acid binding region [nucleotide binding]; other site
765964002151	G-X-X-G motif; other site
765964002152	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
765964002153	Zn2+ binding site [ion binding]; other site
765964002154	Mg2+ binding site [ion binding]; other site
765964002155	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212
765964002156	histidinol phosphate phosphatase, HisJ family; Region: hisJ_fam; TIGR01856
765964002157	signal recognition particle-docking protein FtsY; Region: ftsY; TIGR00064
765964002158	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
765964002159	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
765964002160	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
765964002161	FeS/SAM binding site; other site
765964002162	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
765964002163	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
765964002164	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
765964002165	GTP binding site; other site
765964002166	flagellar biosynthetic protein FlhB; Region: flhB; TIGR00328
765964002167	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
765964002168	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
765964002169	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
765964002170	active site
765964002171	metal binding site [ion binding]; metal-binding site
765964002172	Nitronate monooxygenase; Region: NMO; pfam03060
765964002173	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
765964002174	FMN binding site [chemical binding]; other site
765964002175	substrate binding site [chemical binding]; other site
765964002176	putative catalytic residue [active]
765964002177	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
765964002178	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
765964002179	active site
765964002180	HIGH motif; other site
765964002181	dimer interface [polypeptide binding]; other site
765964002182	KMSKS motif; other site
765964002183	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
765964002184	RNA binding surface [nucleotide binding]; other site
765964002185	(p)ppGpp synthetase, RelA/SpoT family; Region: spoT_relA; TIGR00691
765964002186	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
765964002187	Zn2+ binding site [ion binding]; other site
765964002188	Mg2+ binding site [ion binding]; other site
765964002189	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
765964002190	synthetase active site [active]
765964002191	NTP binding site [chemical binding]; other site
765964002192	metal binding site [ion binding]; metal-binding site
765964002193	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
765964002194	DNA-directed RNA polymerase, subunit K/omega [Transcription]; Region: RpoZ; COG1758
765964002195	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
765964002196	putative nucleotide binding site [chemical binding]; other site
765964002197	uridine monophosphate binding site [chemical binding]; other site
765964002198	homohexameric interface [polypeptide binding]; other site
765964002199	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG1427
765964002200	aconitate hydratase 2; Region: acnB; TIGR00117
765964002201	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
765964002202	substrate binding site [chemical binding]; other site
765964002203	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
765964002204	substrate binding site [chemical binding]; other site
765964002205	ligand binding site [chemical binding]; other site
765964002206	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
765964002207	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
765964002208	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
765964002209	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
765964002210	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
765964002211	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
765964002212	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
765964002213	nucleotide binding region [chemical binding]; other site
765964002214	ATP-binding site [chemical binding]; other site
765964002215	SEC-C motif; Region: SEC-C; pfam02810
765964002216	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
765964002217	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
765964002218	FtsX-like permease family; Region: FtsX; pfam02687
765964002219	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
765964002220	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
765964002221	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
765964002222	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
765964002223	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207
765964002224	metal-binding site [ion binding]
765964002225	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
765964002226	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
765964002227	Soluble P-type ATPase [General function prediction only]; Region: COG4087
765964002228	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
765964002229	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
765964002230	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
765964002231	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
765964002232	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
765964002233	active site
765964002234	catalytic residues [active]
765964002235	metal binding site [ion binding]; metal-binding site
765964002236	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
765964002237	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
765964002238	oligomer interface [polypeptide binding]; other site
765964002239	active site residues [active]
765964002240	trigger factor; Provisional; Region: tig; PRK01490
765964002241	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
765964002242	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
765964002243	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964002244	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
765964002245	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
765964002246	trimer interface [polypeptide binding]; other site
765964002247	dimer interface [polypeptide binding]; other site
765964002248	putative active site [active]
765964002249	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
765964002250	MPT binding site; other site
765964002251	trimer interface [polypeptide binding]; other site
765964002252	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
765964002253	MoaE homodimer interface [polypeptide binding]; other site
765964002254	MoaD interaction [polypeptide binding]; other site
765964002255	active site residues [active]
765964002256	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
765964002257	MoaE interaction surface [polypeptide binding]; other site
765964002258	MoeB interaction surface [polypeptide binding]; other site
765964002259	thiocarboxylated glycine; other site
765964002260	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
765964002261	dimerization interface [polypeptide binding]; other site
765964002262	active site
765964002263	Domain of unknown function (DUF3943); Region: DUF3943; pfam13084
765964002264	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09314
765964002265	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: ribB; TIGR00506
765964002266	GTP cyclohydrolase II [Coenzyme metabolism]; Region: RibA; COG0807
765964002267	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
765964002268	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
765964002269	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
765964002270	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK08455
765964002271	RNA methyltransferase, RsmD family; Region: TIGR00095
765964002272	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
765964002273	Uncharacterized conserved protein [Function unknown]; Region: COG1565
765964002274	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
765964002275	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Region: ThiF; COG0476
765964002276	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
765964002277	ATP binding site [chemical binding]; other site
765964002278	substrate interface [chemical binding]; other site
765964002279	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
765964002280	flagellar motor protein MotA; Validated; Region: PRK08456
765964002281	flagellar motor protein MotB; Reviewed; Region: motB; PRK08457
765964002282	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
765964002283	ligand binding site [chemical binding]; other site
765964002284	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
765964002285	dimer interface [polypeptide binding]; other site
765964002286	conserved gate region; other site
765964002287	ABC-ATPase subunit interface; other site
765964002288	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
765964002289	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
765964002290	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
765964002291	Walker A/P-loop; other site
765964002292	ATP binding site [chemical binding]; other site
765964002293	Q-loop/lid; other site
765964002294	ABC transporter signature motif; other site
765964002295	Walker B; other site
765964002296	D-loop; other site
765964002297	H-loop/switch region; other site
765964002298	excinuclease ABC, C subunit; Region: uvrC; TIGR00194
765964002299	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
765964002300	GIY-YIG motif/motif A; other site
765964002301	active site
765964002302	catalytic site [active]
765964002303	putative DNA binding site [nucleotide binding]; other site
765964002304	metal binding site [ion binding]; metal-binding site
765964002305	UvrB/uvrC motif; Region: UVR; pfam02151
765964002306	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
765964002307	homoserine dehydrogenase; Provisional; Region: PRK06349
765964002308	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
765964002309	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
765964002310	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
765964002311	Predicted endonuclease distantly related to archaeal Holliday junction resolvase [DNA replication, recombination, and repair]; Region: COG0792
765964002312	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
765964002313	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
765964002314	catalytic residues [active]
765964002315	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
765964002316	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
765964002317	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
765964002318	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
765964002319	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
765964002320	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
765964002321	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
765964002322	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
765964002323	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
765964002324	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
765964002325	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
765964002326	active site
765964002327	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; Region: gatA; TIGR00132
765964002328	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
765964002329	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
765964002330	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
765964002331	CoA-binding site [chemical binding]; other site
765964002332	spermidine synthase; Provisional; Region: speE; PRK00536
765964002333	spermidine synthase; Provisional; Region: PRK00811
765964002334	GTP-binding protein Der; Reviewed; Region: PRK00093
765964002335	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
765964002336	G1 box; other site
765964002337	GTP/Mg2+ binding site [chemical binding]; other site
765964002338	Switch I region; other site
765964002339	G2 box; other site
765964002340	Switch II region; other site
765964002341	G3 box; other site
765964002342	G4 box; other site
765964002343	G5 box; other site
765964002344	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
765964002345	G1 box; other site
765964002346	GTP/Mg2+ binding site [chemical binding]; other site
765964002347	Switch I region; other site
765964002348	G2 box; other site
765964002349	G3 box; other site
765964002350	Switch II region; other site
765964002351	G4 box; other site
765964002352	G5 box; other site
765964002353	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
765964002354	IHF dimer interface [polypeptide binding]; other site
765964002355	IHF - DNA interface [nucleotide binding]; other site
765964002356	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
765964002357	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
765964002358	Long-chain fatty acid transport protein [Lipid metabolism]; Region: FadL; COG2067
765964002359	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
765964002360	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
765964002361	NAD(P) binding site [chemical binding]; other site
765964002362	homodimer interface [polypeptide binding]; other site
765964002363	substrate binding site [chemical binding]; other site
765964002364	active site
765964002365	phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Region: coaBC_dfp; TIGR00521
765964002366	Flavoprotein; Region: Flavoprotein; pfam02441
765964002367	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
765964002368	Alpha-2,3-sialyltransferase (CST-I); Region: CST-I; pfam06002
765964002369	Alpha-2,3-sialyltransferase (CST-I); Region: CST-I; pfam06002
765964002370	Alpha-2,3-sialyltransferase (CST-I); Region: CST-I; pfam06002
765964002371	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
765964002372	ligand binding site; other site
765964002373	tetramer interface; other site
765964002374	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
765964002375	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
765964002376	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
765964002377	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
765964002378	ATP binding site [chemical binding]; other site
765964002379	putative Mg++ binding site [ion binding]; other site
765964002380	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
765964002381	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
765964002382	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
765964002383	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
765964002384	HsdM N-terminal domain; Region: HsdM_N; pfam12161
765964002385	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
765964002386	S-adenosylmethionine binding site [chemical binding]; other site
765964002387	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
765964002388	thiamine phosphate binding site [chemical binding]; other site
765964002389	active site
765964002390	pyrophosphate binding site [ion binding]; other site
765964002391	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
765964002392	dimer interface [polypeptide binding]; other site
765964002393	substrate binding site [chemical binding]; other site
765964002394	ATP binding site [chemical binding]; other site
765964002395	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
765964002396	substrate binding site [chemical binding]; other site
765964002397	multimerization interface [polypeptide binding]; other site
765964002398	ATP binding site [chemical binding]; other site
765964002399	HsdM N-terminal domain; Region: HsdM_N; pfam12161
765964002400	potential frameshift: common BLAST hit: gi|188527304|ref|YP_001909991.1| site-specific DNA methyltransferase
765964002401	HaeIII restriction endonuclease; Region: RE_HaeIII; pfam09556
765964002402	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
765964002403	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
765964002404	active site
765964002405	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2958
765964002406	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
765964002407	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
765964002408	Walker A/P-loop; other site
765964002409	ATP binding site [chemical binding]; other site
765964002410	Q-loop/lid; other site
765964002411	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
765964002412	ABC transporter; Region: ABC_tran_2; pfam12848
765964002413	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
765964002414	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
765964002415	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
765964002416	active site
765964002417	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
765964002418	dimer interface [polypeptide binding]; other site
765964002419	active site
765964002420	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
765964002421	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
765964002422	putative ribose interaction site [chemical binding]; other site
765964002423	putative ADP binding site [chemical binding]; other site
765964002424	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
765964002425	active site
765964002426	nucleotide binding site [chemical binding]; other site
765964002427	HIGH motif; other site
765964002428	KMSKS motif; other site
765964002429	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
765964002430	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
765964002431	NAD(P) binding site [chemical binding]; other site
765964002432	active site
765964002433	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
765964002434	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
765964002435	active site
765964002436	motif I; other site
765964002437	motif II; other site
765964002438	Uncharacterized conserved protein [Function unknown]; Region: COG2836
765964002439	pantothenate kinase; Reviewed; Region: PRK13333
765964002440	PQQ-like domain; Region: PQQ_2; pfam13360
765964002441	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
765964002442	trimer interface [polypeptide binding]; other site
765964002443	active site
765964002444	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
765964002445	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
765964002446	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
765964002447	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
765964002448	lipid-A-disaccharide synthase; Region: lpxB; TIGR00215
765964002449	hydrogenase nickel incorporation protein; Provisional; Region: hypA; PRK00564
765964002450	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
765964002451	flagellar hook protein FlgE; Validated; Region: flgE; PRK08425
765964002452	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
765964002453	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
765964002454	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
765964002455	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
765964002456	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
765964002457	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
765964002458	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
765964002459	PhnA protein; Region: PhnA; pfam03831
765964002460	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
765964002461	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
765964002462	tetramer interface [polypeptide binding]; other site
765964002463	heme binding pocket [chemical binding]; other site
765964002464	NADPH binding site [chemical binding]; other site
765964002465	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
765964002466	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
765964002467	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
765964002468	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
765964002469	active site
765964002470	putative DNA-binding cleft [nucleotide binding]; other site
765964002471	dimer interface [polypeptide binding]; other site
765964002472	Uncharacterized conserved protein [Function unknown]; Region: COG1432
765964002473	LabA_like proteins; Region: LabA_like; cd06167
765964002474	putative metal binding site [ion binding]; other site
765964002475	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
765964002476	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
765964002477	Holliday junction DNA helicase, RuvA subunit; Region: ruvA; TIGR00084
765964002478	RuvA N terminal domain; Region: RuvA_N; pfam01330
765964002479	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
765964002480	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
765964002481	MviN-like protein; Region: MVIN; pfam03023
765964002482	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
765964002483	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
765964002484	active site
765964002485	HIGH motif; other site
765964002486	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
765964002487	KMSKS motif; other site
765964002488	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
765964002489	tRNA binding surface [nucleotide binding]; other site
765964002490	anticodon binding site; other site
765964002491	Vacuolating cyotoxin; Region: VacA; pfam02691
765964002492	Autotransporter beta-domain; Region: Autotransporter; pfam03797
765964002493	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
765964002494	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
765964002495	Walker A/P-loop; other site
765964002496	ATP binding site [chemical binding]; other site
765964002497	Q-loop/lid; other site
765964002498	ABC transporter signature motif; other site
765964002499	Walker B; other site
765964002500	D-loop; other site
765964002501	H-loop/switch region; other site
765964002502	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
765964002503	ABC-ATPase subunit  interface; other site
765964002504	dimer interface [polypeptide binding]; other site
765964002505	putative PBP binding regions; other site
765964002506	short chain dehydrogenase; Validated; Region: PRK06182
765964002507	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
765964002508	NADP binding site [chemical binding]; other site
765964002509	active site
765964002510	steroid binding site; other site
765964002511	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
765964002512	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
765964002513	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964002514	potential protein location (hypothetical protein HPCU_04740 [Helicobacter pylori Cuz20]) that overlaps RNA (tRNA-Q)
765964002515	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
765964002516	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
765964002517	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypC; COG0298
765964002518	hydrogenase accessory protein HypB; Region: hypB; TIGR00073
765964002519	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
765964002520	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
765964002521	BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; Region: Pta; COG0857
765964002522	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
765964002523	Acetokinase family; Region: Acetate_kinase; cl17229
765964002524	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
765964002525	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK05842
765964002526	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
765964002527	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
765964002528	flagellar hook protein FlgE; Validated; Region: flgE; PRK05841
765964002529	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
765964002530	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
765964002531	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
765964002532	Part of AAA domain; Region: AAA_19; pfam13245
765964002533	Family description; Region: UvrD_C_2; pfam13538
765964002534	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964002535	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964002536	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
765964002537	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
765964002538	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
765964002539	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
765964002540	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
765964002541	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
765964002542	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
765964002543	ATP-grasp domain; Region: ATP-grasp_4; cl17255
765964002544	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
765964002545	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
765964002546	ATP-grasp domain; Region: ATP-grasp_4; cl17255
765964002547	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
765964002548	IMP binding site; other site
765964002549	dimer interface [polypeptide binding]; other site
765964002550	interdomain contacts; other site
765964002551	partial ornithine binding site; other site
765964002552	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
765964002553	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
765964002554	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
765964002555	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
765964002556	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
765964002557	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
765964002558	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
765964002559	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
765964002560	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
765964002561	Autotransporter beta-domain; Region: Autotransporter; pfam03797
765964002562	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964002563	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
765964002564	active site 1 [active]
765964002565	dimer interface [polypeptide binding]; other site
765964002566	hexamer interface [polypeptide binding]; other site
765964002567	active site 2 [active]
765964002568	recombination protein RecR; Region: recR; TIGR00615
765964002569	RecR protein; Region: RecR; pfam02132
765964002570	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
765964002571	putative active site [active]
765964002572	putative metal-binding site [ion binding]; other site
765964002573	tetramer interface [polypeptide binding]; other site
765964002574	tRNA pseudouridine synthase, TruD family; Region: tRNA_TruD_broad; TIGR00094
765964002575	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
765964002576	Permutation of conserved domain; other site
765964002577	active site
765964002578	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
765964002579	heat shock protein HtpX; Provisional; Region: PRK02870
765964002580	GTP cyclohydrolase I; Region: folE; TIGR00063
765964002581	GTP cyclohydrolase I; Provisional; Region: PLN03044
765964002582	active site
765964002583	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
765964002584	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
765964002585	substrate binding pocket [chemical binding]; other site
765964002586	chain length determination region; other site
765964002587	substrate-Mg2+ binding site; other site
765964002588	catalytic residues [active]
765964002589	aspartate-rich region 1; other site
765964002590	active site lid residues [active]
765964002591	aspartate-rich region 2; other site
765964002592	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
765964002593	6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Region: COG0720
765964002594	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
765964002595	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
765964002596	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
765964002597	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
765964002598	Coenzyme A binding pocket [chemical binding]; other site
765964002599	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
765964002600	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964002601	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
765964002602	putative substrate translocation pore; other site
765964002603	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
765964002604	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
765964002605	dimer interface [polypeptide binding]; other site
765964002606	conserved gate region; other site
765964002607	putative PBP binding loops; other site
765964002608	ABC-ATPase subunit interface; other site
765964002609	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
765964002610	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
765964002611	substrate binding pocket [chemical binding]; other site
765964002612	membrane-bound complex binding site; other site
765964002613	hinge residues; other site
765964002614	alanine racemase; Region: alr; TIGR00492
765964002615	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
765964002616	active site
765964002617	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
765964002618	dimer interface [polypeptide binding]; other site
765964002619	substrate binding site [chemical binding]; other site
765964002620	catalytic residues [active]
765964002621	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
765964002622	amino acid carrier protein; Region: agcS; TIGR00835
765964002623	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
765964002624	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
765964002625	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
765964002626	homotrimer interaction site [polypeptide binding]; other site
765964002627	putative active site [active]
765964002628	TRL-like protein family; Region: TRL; pfam13146
765964002629	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
765964002630	Uncharacterized conserved protein [Function unknown]; Region: COG1576
765964002631	acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Region: accD; TIGR00515
765964002632	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
765964002633	putative recombination protein RecO; Provisional; Region: PRK13908
765964002634	competence/damage-inducible protein CinA C-terminal domain; Region: cinA_cterm; TIGR00199
765964002635	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
765964002636	dimer interface [polypeptide binding]; other site
765964002637	FMN binding site [chemical binding]; other site
765964002638	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
765964002639	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
765964002640	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
765964002641	active site
765964002642	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
765964002643	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
765964002644	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
765964002645	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
765964002646	Putative zinc ribbon domain; Region: DUF164; pfam02591
765964002647	dinuclear metal center protein, YbgI/SA1388 family; Region: YbgI_SA1388; TIGR00486
765964002648	Uncharacterized conserved protein [Function unknown]; Region: COG0327
765964002649	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
765964002650	dimer interface [polypeptide binding]; other site
765964002651	motif 1; other site
765964002652	active site
765964002653	motif 2; other site
765964002654	motif 3; other site
765964002655	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
765964002656	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
765964002657	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
765964002658	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
765964002659	Dynamin family; Region: Dynamin_N; pfam00350
765964002660	G1 box; other site
765964002661	GTP/Mg2+ binding site [chemical binding]; other site
765964002662	G2 box; other site
765964002663	Switch I region; other site
765964002664	G3 box; other site
765964002665	Switch II region; other site
765964002666	G4 box; other site
765964002667	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
765964002668	G1 box; other site
765964002669	GTP/Mg2+ binding site [chemical binding]; other site
765964002670	G2 box; other site
765964002671	Switch I region; other site
765964002672	Dynamin family; Region: Dynamin_N; pfam00350
765964002673	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
765964002674	G3 box; other site
765964002675	Switch II region; other site
765964002676	G4 box; other site
765964002677	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
765964002678	G1 box; other site
765964002679	GTP/Mg2+ binding site [chemical binding]; other site
765964002680	Predicted GTPases (dynamin-related) [General function prediction only]; Region: COG0699
765964002681	G2 box; other site
765964002682	Switch I region; other site
765964002683	G3 box; other site
765964002684	Switch II region; other site
765964002685	G4 box; other site
765964002686	Uncharacterized virulence-associated protein D [Function unknown]; Region: VapD; COG3309
765964002687	Protein of unknown function (DUF3240); Region: DUF3240; pfam11582
765964002688	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
765964002689	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
765964002690	Outer membrane efflux protein; Region: OEP; pfam02321
765964002691	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
765964002692	phosphoglyceromutase; Provisional; Region: PRK05434
765964002693	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
765964002694	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; Region: gatC; TIGR00135
765964002695	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
765964002696	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
765964002697	inhibitor-cofactor binding pocket; inhibition site
765964002698	pyridoxal 5'-phosphate binding site [chemical binding]; other site
765964002699	catalytic residue [active]
765964002700	SurA N-terminal domain; Region: SurA_N_3; cl07813
765964002701	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
765964002702	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
765964002703	cell division protein FtsA; Region: ftsA; TIGR01174
765964002704	Cell division protein FtsA; Region: FtsA; smart00842
765964002705	Cell division protein FtsA; Region: FtsA; pfam14450
765964002706	cell division protein FtsZ; Validated; Region: PRK09330
765964002707	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
765964002708	nucleotide binding site [chemical binding]; other site
765964002709	SulA interaction site; other site
765964002710	potential frameshift: common BLAST hit: gi|308183130|ref|YP_003927257.1| IS606 transposase
765964002711	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
765964002712	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
765964002713	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
765964002714	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
765964002715	Probable transposase; Region: OrfB_IS605; pfam01385
765964002716	Mechanosensitive ion channel; Region: MS_channel; pfam00924
765964002717	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
765964002718	generic binding surface II; other site
765964002719	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; cl01747
765964002720	A nuclease of the HNH/ENDO VII superfamily with conserved LHH; Region: LHH; pfam14411
765964002721	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
765964002722	metal ion-dependent adhesion site (MIDAS); other site
765964002723	Single-stranded DNA-specific exonuclease [DNA replication, recombination, and repair]; Region: RecJ; COG0608
765964002724	DHH family; Region: DHH; pfam01368
765964002725	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
765964002726	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
765964002727	active site
765964002728	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
765964002729	catalytic residues [active]
765964002730	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
765964002731	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
765964002732	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
765964002733	putative ADP-binding pocket [chemical binding]; other site
765964002734	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
765964002735	active site 2 [active]
765964002736	active site 1 [active]
765964002737	Methyltransferase domain; Region: Methyltransf_23; pfam13489
765964002738	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
765964002739	S-adenosylmethionine binding site [chemical binding]; other site
765964002740	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
765964002741	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
765964002742	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
765964002743	active site
765964002744	HIGH motif; other site
765964002745	KMSKS motif; other site
765964002746	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
765964002747	anticodon binding site; other site
765964002748	tRNA binding surface [nucleotide binding]; other site
765964002749	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
765964002750	dimer interface [polypeptide binding]; other site
765964002751	putative tRNA-binding site [nucleotide binding]; other site
765964002752	Mycolic acid cyclopropane synthetase; Region: CMAS; pfam02353
765964002753	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
765964002754	S-adenosylmethionine binding site [chemical binding]; other site
765964002755	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
765964002756	Mechanosensitive ion channel; Region: MS_channel; pfam00924
765964002757	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
765964002758	GMP synthase; Reviewed; Region: guaA; PRK00074
765964002759	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
765964002760	AMP/PPi binding site [chemical binding]; other site
765964002761	candidate oxyanion hole; other site
765964002762	catalytic triad [active]
765964002763	potential glutamine specificity residues [chemical binding]; other site
765964002764	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
765964002765	ATP Binding subdomain [chemical binding]; other site
765964002766	Ligand Binding sites [chemical binding]; other site
765964002767	Dimerization subdomain; other site
765964002768	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
765964002769	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
765964002770	molybdopterin cofactor binding site [chemical binding]; other site
765964002771	substrate binding site [chemical binding]; other site
765964002772	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
765964002773	molybdopterin cofactor binding site; other site
765964002774	Protein of unknown function (DUF3972); Region: DUF3972; pfam13118
765964002775	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
765964002776	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
765964002777	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
765964002778	catalytic residue [active]
765964002779	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
765964002780	nucleotide binding site/active site [active]
765964002781	HIT family signature motif; other site
765964002782	catalytic residue [active]
765964002783	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
765964002784	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
765964002785	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
765964002786	dimer interface [polypeptide binding]; other site
765964002787	motif 1; other site
765964002788	active site
765964002789	motif 2; other site
765964002790	motif 3; other site
765964002791	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
765964002792	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
765964002793	putative tRNA-binding site [nucleotide binding]; other site
765964002794	tRNA synthetase B5 domain; Region: B5; pfam03484
765964002795	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
765964002796	dimer interface [polypeptide binding]; other site
765964002797	motif 1; other site
765964002798	motif 3; other site
765964002799	motif 2; other site
765964002800	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
765964002801	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
765964002802	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
765964002803	hinge; other site
765964002804	active site
765964002805	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
765964002806	LytB protein; Region: LYTB; pfam02401
765964002807	ribosomal protein S1; Region: rpsA; TIGR00717
765964002808	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
765964002809	RNA binding site [nucleotide binding]; other site
765964002810	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
765964002811	RNA binding site [nucleotide binding]; other site
765964002812	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
765964002813	RNA binding site [nucleotide binding]; other site
765964002814	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
765964002815	RNA binding site [nucleotide binding]; other site
765964002816	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
765964002817	RNA binding site [nucleotide binding]; other site
765964002818	D-3-phosphoglycerate dehydrogenase; Region: PGDH; TIGR01327
765964002819	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
765964002820	ligand binding site [chemical binding]; other site
765964002821	NAD binding site [chemical binding]; other site
765964002822	dimerization interface [polypeptide binding]; other site
765964002823	catalytic site [active]
765964002824	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
765964002825	putative L-serine binding site [chemical binding]; other site
765964002826	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
765964002827	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
765964002828	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
765964002829	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
765964002830	catalytic residue [active]
765964002831	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
765964002832	putative active site [active]
765964002833	putative metal binding site [ion binding]; other site
765964002834	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
765964002835	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
765964002836	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
765964002837	active site
765964002838	phosphorylation site [posttranslational modification]
765964002839	intermolecular recognition site; other site
765964002840	dimerization interface [polypeptide binding]; other site
765964002841	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
765964002842	putative binding surface; other site
765964002843	active site
765964002844	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
765964002845	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
765964002846	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
765964002847	ATP binding site [chemical binding]; other site
765964002848	Mg2+ binding site [ion binding]; other site
765964002849	G-X-G motif; other site
765964002850	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
765964002851	Response regulator receiver domain; Region: Response_reg; pfam00072
765964002852	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
765964002853	active site
765964002854	phosphorylation site [posttranslational modification]
765964002855	intermolecular recognition site; other site
765964002856	dimerization interface [polypeptide binding]; other site
765964002857	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
765964002858	putative CheA interaction surface; other site
765964002859	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
765964002860	dimer interface [polypeptide binding]; other site
765964002861	catalytic triad [active]
765964002862	peroxidatic and resolving cysteines [active]
765964002863	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
765964002864	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
765964002865	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
765964002866	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
765964002867	S-adenosylmethionine binding site [chemical binding]; other site
765964002868	primosome assembly protein PriA; Validated; Region: PRK05580
765964002869	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
765964002870	ATP binding site [chemical binding]; other site
765964002871	putative Mg++ binding site [ion binding]; other site
765964002872	helicase superfamily c-terminal domain; Region: HELICc; smart00490
765964002873	Sporulation related domain; Region: SPOR; pfam05036
765964002874	Peptidase family M48; Region: Peptidase_M48; pfam01435
765964002875	HemK family putative methylases; Region: hemK_fam; TIGR00536
765964002876	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
765964002877	glutamate dehydrogenase; Provisional; Region: PRK09414
765964002878	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
765964002879	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
765964002880	NAD(P) binding site [chemical binding]; other site
765964002881	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
765964002882	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
765964002883	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
765964002884	SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide...; Region: SoxW; cd02951
765964002885	catalytic residues [active]
765964002886	ferrochelatase; Region: hemH; TIGR00109
765964002887	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
765964002888	C-terminal domain interface [polypeptide binding]; other site
765964002889	active site
765964002890	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
765964002891	active site
765964002892	N-terminal domain interface [polypeptide binding]; other site
765964002893	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
765964002894	RNA methyltransferase, RsmE family; Region: TIGR00046
765964002895	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964002896	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
765964002897	trimer interface [polypeptide binding]; other site
765964002898	active site
765964002899	acetyl-CoA carboxylase, biotin carboxyl carrier protein; Region: BCCP; TIGR00531
765964002900	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
765964002901	carboxyltransferase (CT) interaction site; other site
765964002902	biotinylation site [posttranslational modification]; other site
765964002903	biotin carboxylase; Validated; Region: PRK08462
765964002904	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
765964002905	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
765964002906	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
765964002907	Methyltransferase FkbM domain; Region: Methyltransf_21; cl17387
765964002908	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
765964002909	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
765964002910	inhibitor-cofactor binding pocket; inhibition site
765964002911	pyridoxal 5'-phosphate binding site [chemical binding]; other site
765964002912	catalytic residue [active]
765964002913	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
765964002914	dimer interface [polypeptide binding]; other site
765964002915	putative radical transfer pathway; other site
765964002916	diiron center [ion binding]; other site
765964002917	tyrosyl radical; other site
765964002918	protein-L-isoaspartate(D-aspartate) O-methyltransferase; Region: pimt; TIGR00080
765964002919	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
765964002920	S-adenosylmethionine binding site [chemical binding]; other site
765964002921	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
765964002922	Predicted permeases [General function prediction only]; Region: COG0795
765964002923	tRNA pseudouridine(38-40) synthase; Region: hisT_truA; TIGR00071
765964002924	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
765964002925	dimerization interface 3.5A [polypeptide binding]; other site
765964002926	active site
765964002927	UDP-glucose-4-epimerase GalE; Region: galE; TIGR01179
765964002928	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
765964002929	NAD binding site [chemical binding]; other site
765964002930	homodimer interface [polypeptide binding]; other site
765964002931	active site
765964002932	substrate binding site [chemical binding]; other site
765964002933	potential protein location (hypothetical protein HPCU_05545 [Helicobacter pylori Cuz20]) that overlaps RNA (tRNA-I)
765964002934	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
765964002935	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
765964002936	putative NAD(P) binding site [chemical binding]; other site
765964002937	homodimer interface [polypeptide binding]; other site
765964002938	homotetramer interface [polypeptide binding]; other site
765964002939	active site
765964002940	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
765964002941	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
765964002942	binding surface
765964002943	TPR motif; other site
765964002944	Sel1-like repeats; Region: SEL1; smart00671
765964002945	Sel1-like repeats; Region: SEL1; smart00671
765964002946	Sel1-like repeats; Region: SEL1; smart00671
765964002947	Entner-Doudoroff aldolase; Region: eda; TIGR01182
765964002948	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
765964002949	active site
765964002950	intersubunit interface [polypeptide binding]; other site
765964002951	catalytic residue [active]
765964002952	phosphogluconate dehydratase; Validated; Region: PRK09054
765964002953	6-phosphogluconate dehydratase; Region: edd; TIGR01196
765964002954	Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Region: Zwf; COG0364
765964002955	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
765964002956	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
765964002957	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
765964002958	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
765964002959	putative active site [active]
765964002960	glucokinase, proteobacterial type; Region: glk; TIGR00749
765964002961	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
765964002962	nucleotide binding site [chemical binding]; other site
765964002963	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
765964002964	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
765964002965	putative NAD(P) binding site [chemical binding]; other site
765964002966	putative substrate binding site [chemical binding]; other site
765964002967	catalytic Zn binding site [ion binding]; other site
765964002968	structural Zn binding site [ion binding]; other site
765964002969	dimer interface [polypeptide binding]; other site
765964002970	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
765964002971	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
765964002972	active site
765964002973	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
765964002974	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
765964002975	active site
765964002976	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964002977	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; cl00546
765964002978	pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; Provisional; Region: PRK14029
765964002979	pyruvate flavodoxin oxidoreductase subunit delta; Reviewed; Region: porD; PRK09625
765964002980	4Fe-4S binding domain; Region: Fer4; pfam00037
765964002981	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
765964002982	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
765964002983	dimer interface [polypeptide binding]; other site
765964002984	PYR/PP interface [polypeptide binding]; other site
765964002985	TPP binding site [chemical binding]; other site
765964002986	substrate binding site [chemical binding]; other site
765964002987	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
765964002988	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
765964002989	Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea...; Region: TPP_PFOR_porB_like; cd03376
765964002990	TPP-binding site [chemical binding]; other site
765964002991	putative dimer interface [polypeptide binding]; other site
765964002992	adenylosuccinate lyase; Provisional; Region: PRK08470
765964002993	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
765964002994	tetramer interface [polypeptide binding]; other site
765964002995	active site
765964002996	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
765964002997	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964002998	excinuclease ABC subunit B; Provisional; Region: PRK05298
765964002999	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
765964003000	ATP binding site [chemical binding]; other site
765964003001	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
765964003002	putative Mg++ binding site [ion binding]; other site
765964003003	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
765964003004	nucleotide binding region [chemical binding]; other site
765964003005	ATP-binding site [chemical binding]; other site
765964003006	Ultra-violet resistance protein B; Region: UvrB; pfam12344
765964003007	UvrB/uvrC motif; Region: UVR; pfam02151
765964003008	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
765964003009	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
765964003010	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
765964003011	binding surface
765964003012	TPR motif; other site
765964003013	Sel1-like repeats; Region: SEL1; smart00671
765964003014	Sel1-like repeats; Region: SEL1; smart00671
765964003015	Sel1 repeat; Region: Sel1; cl02723
765964003016	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
765964003017	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
765964003018	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08471
765964003019	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
765964003020	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
765964003021	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
765964003022	cofactor binding site; other site
765964003023	DNA binding site [nucleotide binding]
765964003024	substrate interaction site [chemical binding]; other site
765964003025	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
765964003026	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
765964003027	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
765964003028	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
765964003029	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
765964003030	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
765964003031	ligand binding site [chemical binding]; other site
765964003032	translocation protein TolB; Provisional; Region: tolB; PRK04043
765964003033	TolB amino-terminal domain; Region: TolB_N; pfam04052
765964003034	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
765964003035	TonB C terminal; Region: TonB_2; pfam13103
765964003036	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
765964003037	TolR protein; Region: tolR; TIGR02801
765964003038	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
765964003039	ATP synthase, F1 epsilon subunit (delta in mitochondria); Region: ATP_synt_epsi; TIGR01216
765964003040	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
765964003041	gamma subunit interface [polypeptide binding]; other site
765964003042	epsilon subunit interface [polypeptide binding]; other site
765964003043	LBP interface [polypeptide binding]; other site
765964003044	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
765964003045	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
765964003046	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
765964003047	alpha subunit interaction interface [polypeptide binding]; other site
765964003048	Walker A motif; other site
765964003049	ATP binding site [chemical binding]; other site
765964003050	Walker B motif; other site
765964003051	inhibitor binding site; inhibition site
765964003052	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
765964003053	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
765964003054	core domain interface [polypeptide binding]; other site
765964003055	delta subunit interface [polypeptide binding]; other site
765964003056	epsilon subunit interface [polypeptide binding]; other site
765964003057	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
765964003058	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
765964003059	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
765964003060	beta subunit interaction interface [polypeptide binding]; other site
765964003061	Walker A motif; other site
765964003062	ATP binding site [chemical binding]; other site
765964003063	Walker B motif; other site
765964003064	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
765964003065	F0F1 ATP synthase subunit delta; Provisional; Region: PRK13431
765964003066	F0F1 ATP synthase subunit B; Validated; Region: PRK08475
765964003067	F0F1 ATP synthase subunit B'; Validated; Region: PRK08476
765964003068	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
765964003069	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
765964003070	ParB-like nuclease domain; Region: ParB; smart00470
765964003071	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
765964003072	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
765964003073	P-loop; other site
765964003074	Magnesium ion binding site [ion binding]; other site
765964003075	biotin--protein ligase; Provisional; Region: PRK08477
765964003076	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
765964003077	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
765964003078	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
765964003079	putative active site [active]
765964003080	substrate binding site [chemical binding]; other site
765964003081	putative cosubstrate binding site; other site
765964003082	catalytic site [active]
765964003083	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
765964003084	substrate binding site [chemical binding]; other site
765964003085	potential frameshift: common BLAST hit: gi|210135301|ref|YP_002301740.1| ATPase
765964003086	ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only]; Region: COG2401
765964003087	PHP-associated; Region: PHP_C; pfam13263
765964003088	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
765964003089	Walker A/P-loop; other site
765964003090	ATP binding site [chemical binding]; other site
765964003091	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
765964003092	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
765964003093	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
765964003094	tRNA (Guanine-1)-methyltransferase; Region: tRNA_m1G_MT; cl00407
765964003095	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK14593
765964003096	RimM N-terminal domain; Region: RimM; pfam01782
765964003097	PRC-barrel domain; Region: PRC; pfam05239
765964003098	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
765964003099	KH domain; Region: KH_4; pfam13083
765964003100	G-X-X-G motif; other site
765964003101	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
765964003102	signal recognition particle protein; Provisional; Region: PRK10867
765964003103	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
765964003104	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
765964003105	P loop; other site
765964003106	GTP binding site [chemical binding]; other site
765964003107	Signal peptide binding domain; Region: SRP_SPB; pfam02978
765964003108	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
765964003109	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
765964003110	active site
765964003111	HIGH motif; other site
765964003112	nucleotide binding site [chemical binding]; other site
765964003113	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
765964003114	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
765964003115	active site
765964003116	KMSKS motif; other site
765964003117	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
765964003118	anticodon binding site; other site
765964003119	flagellar assembly protein FliW; Provisional; Region: PRK13283
765964003120	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
765964003121	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
765964003122	active site
765964003123	homodimer interface [polypeptide binding]; other site
765964003124	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964003125	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964003126	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
765964003127	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
765964003128	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
765964003129	Fic/DOC family; Region: Fic; cl00960
765964003130	metal-binding heat shock protein; Provisional; Region: PRK00016
765964003131	flavodoxin FldA; Validated; Region: PRK09267
765964003132	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
765964003133	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
765964003134	Uncharacterized protein, possibly involved in nitrogen fixation [Inorganic ion transport and metabolism]; Region: FixS; COG3197
765964003135	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
765964003136	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
765964003137	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
765964003138	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
765964003139	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
765964003140	active site
765964003141	dimer interface [polypeptide binding]; other site
765964003142	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
765964003143	dimer interface [polypeptide binding]; other site
765964003144	active site
765964003145	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
765964003146	carbon starvation protein A; Provisional; Region: PRK15015
765964003147	Carbon starvation protein CstA; Region: CstA; pfam02554
765964003148	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
765964003149	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
765964003150	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
765964003151	dimer interface [polypeptide binding]; other site
765964003152	conserved gate region; other site
765964003153	putative PBP binding loops; other site
765964003154	ABC-ATPase subunit interface; other site
765964003155	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
765964003156	dimer interface [polypeptide binding]; other site
765964003157	conserved gate region; other site
765964003158	putative PBP binding loops; other site
765964003159	ABC-ATPase subunit interface; other site
765964003160	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
765964003161	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
765964003162	Walker A/P-loop; other site
765964003163	ATP binding site [chemical binding]; other site
765964003164	Q-loop/lid; other site
765964003165	ABC transporter signature motif; other site
765964003166	Walker B; other site
765964003167	D-loop; other site
765964003168	H-loop/switch region; other site
765964003169	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
765964003170	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
765964003171	substrate binding pocket [chemical binding]; other site
765964003172	membrane-bound complex binding site; other site
765964003173	hinge residues; other site
765964003174	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
765964003175	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
765964003176	putative substrate translocation pore; other site
765964003177	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
765964003178	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964003179	purine-nucleoside phosphorylase, family 1 (deoD); Region: deoD; TIGR00107
765964003180	phosphopentomutase; Provisional; Region: PRK05362
765964003181	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
765964003182	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
765964003183	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
765964003184	Nucleoside recognition; Region: Gate; pfam07670
765964003185	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
765964003186	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
765964003187	HSP70 interaction site [polypeptide binding]; other site
765964003188	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
765964003189	Major Facilitator Superfamily; Region: MFS_1; pfam07690
765964003190	putative substrate translocation pore; other site
765964003191	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
765964003192	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
765964003193	Ligand Binding Site [chemical binding]; other site
765964003194	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
765964003195	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
765964003196	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
765964003197	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
765964003198	putative arabinose transporter; Provisional; Region: PRK03545
765964003199	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
765964003200	putative substrate translocation pore; other site
765964003201	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
765964003202	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
765964003203	active site
765964003204	zinc binding site [ion binding]; other site
765964003205	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
765964003206	aspartate-semialdehyde dehydrogenase (peptidoglycan organisms); Region: asd_B; TIGR01296
765964003207	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
765964003208	Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: HisS; COG0124
765964003209	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
765964003210	dimer interface [polypeptide binding]; other site
765964003211	motif 1; other site
765964003212	active site
765964003213	motif 2; other site
765964003214	motif 3; other site
765964003215	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
765964003216	anticodon binding site; other site
765964003217	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
765964003218	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
765964003219	putative active site [active]
765964003220	elongation factor G; Reviewed; Region: PRK00007
765964003221	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
765964003222	G1 box; other site
765964003223	putative GEF interaction site [polypeptide binding]; other site
765964003224	GTP/Mg2+ binding site [chemical binding]; other site
765964003225	Switch I region; other site
765964003226	G2 box; other site
765964003227	G3 box; other site
765964003228	Switch II region; other site
765964003229	G4 box; other site
765964003230	G5 box; other site
765964003231	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
765964003232	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
765964003233	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
765964003234	30S ribosomal protein S7; Validated; Region: PRK05302
765964003235	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
765964003236	S17 interaction site [polypeptide binding]; other site
765964003237	S8 interaction site; other site
765964003238	16S rRNA interaction site [nucleotide binding]; other site
765964003239	streptomycin interaction site [chemical binding]; other site
765964003240	23S rRNA interaction site [nucleotide binding]; other site
765964003241	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
765964003242	bifunctional DNA-directed RNA polymerase subunit beta/beta'; Reviewed; Region: PRK09603
765964003243	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
765964003244	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
765964003245	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
765964003246	RPB11 interaction site [polypeptide binding]; other site
765964003247	RPB12 interaction site [polypeptide binding]; other site
765964003248	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
765964003249	RPB3 interaction site [polypeptide binding]; other site
765964003250	RPB1 interaction site [polypeptide binding]; other site
765964003251	RPB11 interaction site [polypeptide binding]; other site
765964003252	RPB10 interaction site [polypeptide binding]; other site
765964003253	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
765964003254	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
765964003255	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
765964003256	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
765964003257	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
765964003258	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
765964003259	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
765964003260	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
765964003261	DNA binding site [nucleotide binding]
765964003262	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
765964003263	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
765964003264	core dimer interface [polypeptide binding]; other site
765964003265	peripheral dimer interface [polypeptide binding]; other site
765964003266	L10 interface [polypeptide binding]; other site
765964003267	L11 interface [polypeptide binding]; other site
765964003268	putative EF-Tu interaction site [polypeptide binding]; other site
765964003269	putative EF-G interaction site [polypeptide binding]; other site
765964003270	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
765964003271	23S rRNA interface [nucleotide binding]; other site
765964003272	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
765964003273	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
765964003274	mRNA/rRNA interface [nucleotide binding]; other site
765964003275	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
765964003276	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
765964003277	23S rRNA interface [nucleotide binding]; other site
765964003278	L7/L12 interface [polypeptide binding]; other site
765964003279	putative thiostrepton binding site; other site
765964003280	L25 interface [polypeptide binding]; other site
765964003281	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
765964003282	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
765964003283	putative homodimer interface [polypeptide binding]; other site
765964003284	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
765964003285	heterodimer interface [polypeptide binding]; other site
765964003286	homodimer interface [polypeptide binding]; other site
765964003287	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; cl00481
765964003288	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
765964003289	elongation factor Tu; Reviewed; Region: PRK00049
765964003290	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
765964003291	G1 box; other site
765964003292	GEF interaction site [polypeptide binding]; other site
765964003293	GTP/Mg2+ binding site [chemical binding]; other site
765964003294	Switch I region; other site
765964003295	G2 box; other site
765964003296	G3 box; other site
765964003297	Switch II region; other site
765964003298	G4 box; other site
765964003299	G5 box; other site
765964003300	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
765964003301	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
765964003302	Antibiotic Binding Site [chemical binding]; other site
765964003303	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
765964003304	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
765964003305	Walker A/P-loop; other site
765964003306	ATP binding site [chemical binding]; other site
765964003307	Q-loop/lid; other site
765964003308	ABC transporter signature motif; other site
765964003309	Walker B; other site
765964003310	D-loop; other site
765964003311	H-loop/switch region; other site
765964003312	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
765964003313	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
765964003314	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
765964003315	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; pfam02086
765964003316	Helicobacter pylori IceA2 protein; Region: IceA2; pfam05862
765964003317	serine O-acetyltransferase; Region: cysE; TIGR01172
765964003318	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
765964003319	trimer interface [polypeptide binding]; other site
765964003320	active site
765964003321	substrate binding site [chemical binding]; other site
765964003322	CoA binding site [chemical binding]; other site
765964003323	F0F1 ATP synthase subunit C; Validated; Region: PRK08482
765964003324	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
765964003325	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
765964003326	oligomer interface [polypeptide binding]; other site
765964003327	RNA binding site [nucleotide binding]; other site
765964003328	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
765964003329	oligomer interface [polypeptide binding]; other site
765964003330	RNA binding site [nucleotide binding]; other site
765964003331	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
765964003332	putative nucleic acid binding region [nucleotide binding]; other site
765964003333	G-X-X-G motif; other site
765964003334	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
765964003335	RNA binding site [nucleotide binding]; other site
765964003336	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG1926
765964003337	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
765964003338	Organic solvent tolerance protein; Region: OstA_C; pfam04453
765964003339	Predicted membrane protein/domain [Function unknown]; Region: COG1714
765964003340	phosphoribosylamine--glycine ligase; Region: purD; TIGR00877
765964003341	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
765964003342	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
765964003343	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
765964003344	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
765964003345	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
765964003346	Walker A/P-loop; other site
765964003347	ATP binding site [chemical binding]; other site
765964003348	Q-loop/lid; other site
765964003349	ABC transporter signature motif; other site
765964003350	Walker B; other site
765964003351	D-loop; other site
765964003352	H-loop/switch region; other site
765964003353	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
765964003354	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
765964003355	catalytic residue [active]
765964003356	putative FPP diphosphate  binding site; other site
765964003357	putative FPP binding hydrophobic cleft; other site
765964003358	dimer interface [polypeptide binding]; other site
765964003359	putative IPP diphosphate binding site; other site
765964003360	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
765964003361	FAD binding domain; Region: FAD_binding_4; pfam01565
765964003362	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
765964003363	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
765964003364	active site residue [active]
765964003365	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
765964003366	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
765964003367	active site
765964003368	camphor resistance protein CrcB; Provisional; Region: PRK14204
765964003369	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
765964003370	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
765964003371	FeS/SAM binding site; other site
765964003372	HemN C-terminal domain; Region: HemN_C; pfam06969
765964003373	Cytochrome c553 [Energy production and conversion]; Region: COG2863
765964003374	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
765964003375	putative active site [active]
765964003376	Ap4A binding site [chemical binding]; other site
765964003377	nudix motif; other site
765964003378	putative metal binding site [ion binding]; other site
765964003379	aspartate kinase; Reviewed; Region: PRK06635
765964003380	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
765964003381	putative nucleotide binding site [chemical binding]; other site
765964003382	putative catalytic residues [active]
765964003383	putative Mg ion binding site [ion binding]; other site
765964003384	putative aspartate binding site [chemical binding]; other site
765964003385	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
765964003386	putative allosteric regulatory site; other site
765964003387	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
765964003388	putative allosteric regulatory residue; other site
765964003389	DNA replication regulator; Region: HobA; pfam12163
765964003390	DNA polymerase III subunit delta'; Validated; Region: PRK08485
765964003391	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
765964003392	dihydropteroate synthase; Region: DHPS; TIGR01496
765964003393	substrate binding pocket [chemical binding]; other site
765964003394	dimer interface [polypeptide binding]; other site
765964003395	inhibitor binding site; inhibition site
765964003396	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
765964003397	EamA-like transporter family; Region: EamA; pfam00892
765964003398	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
765964003399	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2952
765964003400	Carbamoylphosphate synthase small subunit [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarA; COG0505
765964003401	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
765964003402	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
765964003403	catalytic site [active]
765964003404	subunit interface [polypeptide binding]; other site
765964003405	formamidase; Provisional; Region: amiF; PRK13287
765964003406	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
765964003407	multimer interface [polypeptide binding]; other site
765964003408	active site
765964003409	catalytic triad [active]
765964003410	dimer interface [polypeptide binding]; other site
765964003411	Maf-like protein; Region: Maf; pfam02545
765964003412	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
765964003413	active site
765964003414	dimer interface [polypeptide binding]; other site
765964003415	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
765964003416	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
765964003417	motif 1; other site
765964003418	active site
765964003419	motif 2; other site
765964003420	motif 3; other site
765964003421	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
765964003422	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
765964003423	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964003424	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964003425	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
765964003426	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
765964003427	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
765964003428	dimer interface [polypeptide binding]; other site
765964003429	ssDNA binding site [nucleotide binding]; other site
765964003430	tetramer (dimer of dimers) interface [polypeptide binding]; other site
765964003431	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
765964003432	DNA polymerase III subunit delta; Validated; Region: PRK08487
765964003433	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
765964003434	Exoribonuclease R [Transcription]; Region: VacB; COG0557
765964003435	RNB domain; Region: RNB; pfam00773
765964003436	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
765964003437	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
765964003438	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
765964003439	shikimate binding site; other site
765964003440	NAD(P) binding site [chemical binding]; other site
765964003441	Bacterial SH3 domain; Region: SH3_3; pfam08239
765964003442	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
765964003443	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
765964003444	dimer interface [polypeptide binding]; other site
765964003445	conserved gate region; other site
765964003446	putative PBP binding loops; other site
765964003447	ABC-ATPase subunit interface; other site
765964003448	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
765964003449	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
765964003450	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
765964003451	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
765964003452	active site
765964003453	HIGH motif; other site
765964003454	dimer interface [polypeptide binding]; other site
765964003455	KMSKS motif; other site
765964003456	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
765964003457	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
765964003458	S-adenosylmethionine binding site [chemical binding]; other site
765964003459	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
765964003460	ribosome recycling factor; Reviewed; Region: frr; PRK00083
765964003461	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
765964003462	hinge region; other site
765964003463	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
765964003464	active site
765964003465	RDD family; Region: RDD; pfam06271
765964003466	NAD-dependent deacetylase; Provisional; Region: PRK00481
765964003467	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
765964003468	NAD+ binding site [chemical binding]; other site
765964003469	substrate binding site [chemical binding]; other site
765964003470	Zn binding site [ion binding]; other site
765964003471	NADH dehydrogenase subunit A; Validated; Region: PRK08489
765964003472	NADH dehydrogenase subunit B; Validated; Region: PRK06411
765964003473	NADH dehydrogenase subunit C; Provisional; Region: PRK08491
765964003474	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
765964003475	NADH dehydrogenase subunit D; Validated; Region: PRK06075
765964003476	NADH dehydrogenase I, D subunit; Region: NuoD; TIGR01962
765964003477	NADH dehydrogenase subunit G; Validated; Region: PRK08493
765964003478	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
765964003479	catalytic loop [active]
765964003480	iron binding site [ion binding]; other site
765964003481	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
765964003482	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
765964003483	molybdopterin cofactor binding site; other site
765964003484	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
765964003485	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
765964003486	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
765964003487	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
765964003488	4Fe-4S binding domain; Region: Fer4; cl02805
765964003489	4Fe-4S binding domain; Region: Fer4; pfam00037
765964003490	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
765964003491	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
765964003492	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
765964003493	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
765964003494	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
765964003495	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
765964003496	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
765964003497	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
765964003498	proton-translocating NADH-quinone oxidoreductase, chain N; Region: NDH_I_N; TIGR01770
765964003499	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
765964003500	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
765964003501	Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats [Function unknown]; Region: COG4700
765964003502	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
765964003503	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
765964003504	active site
765964003505	substrate binding site [chemical binding]; other site
765964003506	metal binding site [ion binding]; metal-binding site
765964003507	Thiamine pyrophosphokinase; Region: TPK; cl08415
765964003508	thiamine binding site [chemical binding]; other site
765964003509	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
765964003510	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
765964003511	substrate binding site [chemical binding]; other site
765964003512	active site
765964003513	catalytic residues [active]
765964003514	heterodimer interface [polypeptide binding]; other site
765964003515	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
765964003516	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
765964003517	pyridoxal 5'-phosphate binding site [chemical binding]; other site
765964003518	catalytic residue [active]
765964003519	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
765964003520	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
765964003521	active site
765964003522	ribulose/triose binding site [chemical binding]; other site
765964003523	phosphate binding site [ion binding]; other site
765964003524	substrate (anthranilate) binding pocket [chemical binding]; other site
765964003525	product (indole) binding pocket [chemical binding]; other site
765964003526	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
765964003527	active site
765964003528	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
765964003529	anthranilate phosphoribosyltransferase; Region: trpD; TIGR01245
765964003530	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
765964003531	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
765964003532	Glutamine amidotransferase class-I; Region: GATase; pfam00117
765964003533	glutamine binding [chemical binding]; other site
765964003534	catalytic triad [active]
765964003535	anthranilate synthase component I, proteobacterial subset; Region: trpE_proteo; TIGR00565
765964003536	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
765964003537	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
765964003538	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
765964003539	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
765964003540	putative active site [active]
765964003541	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
765964003542	active site
765964003543	motif I; other site
765964003544	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
765964003545	motif II; other site
765964003546	Uncharacterized conserved protein [Function unknown]; Region: COG2353
765964003547	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
765964003548	Nicotinamide mononucleotide transporter [Coenzyme metabolism]; Region: PnuC; COG3201
765964003549	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
765964003550	Thiamine pyrophosphokinase; Region: TPK; cd07995
765964003551	active site
765964003552	dimerization interface [polypeptide binding]; other site
765964003553	thiamine binding site [chemical binding]; other site
765964003554	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
765964003555	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
765964003556	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
765964003557	alphaNTD homodimer interface [polypeptide binding]; other site
765964003558	alphaNTD - beta interaction site [polypeptide binding]; other site
765964003559	alphaNTD - beta' interaction site [polypeptide binding]; other site
765964003560	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
765964003561	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
765964003562	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
765964003563	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
765964003564	RNA binding surface [nucleotide binding]; other site
765964003565	30S ribosomal protein S11; Validated; Region: PRK05309
765964003566	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
765964003567	30S ribosomal protein S13; Region: bact_S13; TIGR03631
765964003568	Ribosomal protein L36; Region: Ribosomal_L36; cl00380
765964003569	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
765964003570	rRNA binding site [nucleotide binding]; other site
765964003571	predicted 30S ribosome binding site; other site
765964003572	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
765964003573	active site
765964003574	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
765964003575	SecY translocase; Region: SecY; pfam00344
765964003576	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
765964003577	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
765964003578	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
765964003579	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
765964003580	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
765964003581	23S rRNA interface [nucleotide binding]; other site
765964003582	5S rRNA interface [nucleotide binding]; other site
765964003583	L27 interface [polypeptide binding]; other site
765964003584	L5 interface [polypeptide binding]; other site
765964003585	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
765964003586	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
765964003587	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
765964003588	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
765964003589	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
765964003590	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
765964003591	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
765964003592	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
765964003593	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
765964003594	RNA binding site [nucleotide binding]; other site
765964003595	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
765964003596	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
765964003597	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
765964003598	putative translocon interaction site; other site
765964003599	23S rRNA interface [nucleotide binding]; other site
765964003600	signal recognition particle (SRP54) interaction site; other site
765964003601	L23 interface [polypeptide binding]; other site
765964003602	trigger factor interaction site; other site
765964003603	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
765964003604	23S rRNA interface [nucleotide binding]; other site
765964003605	5S rRNA interface [nucleotide binding]; other site
765964003606	putative antibiotic binding site [chemical binding]; other site
765964003607	L25 interface [polypeptide binding]; other site
765964003608	L27 interface [polypeptide binding]; other site
765964003609	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
765964003610	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
765964003611	G-X-X-G motif; other site
765964003612	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
765964003613	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
765964003614	putative translocon binding site; other site
765964003615	protein-rRNA interface [nucleotide binding]; other site
765964003616	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
765964003617	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
765964003618	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
765964003619	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
765964003620	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
765964003621	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
765964003622	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
765964003623	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
765964003624	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
765964003625	AAA domain; Region: AAA_14; pfam13173
765964003626	Helix-turn-helix domain; Region: HTH_36; pfam13730
765964003627	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
765964003628	RNA/DNA hybrid binding site [nucleotide binding]; other site
765964003629	active site
765964003630	fumarate hydratase; Reviewed; Region: fumC; PRK00485
765964003631	Class II fumarases; Region: Fumarase_classII; cd01362
765964003632	active site
765964003633	tetramer interface [polypeptide binding]; other site
765964003634	YtkA-like; Region: YtkA; pfam13115
765964003635	Outer membrane efflux protein; Region: OEP; pfam02321
765964003636	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
765964003637	HlyD family secretion protein; Region: HlyD_3; pfam13437
765964003638	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
765964003639	Predicted branched-chain amino acid permeases (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlD; COG1687
765964003640	AzlC protein; Region: AzlC; cl00570
765964003641	chaperone protein DnaJ; Provisional; Region: PRK14288
765964003642	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
765964003643	HSP70 interaction site [polypeptide binding]; other site
765964003644	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
765964003645	substrate binding site [polypeptide binding]; other site
765964003646	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
765964003647	Zn binding sites [ion binding]; other site
765964003648	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
765964003649	substrate binding site [polypeptide binding]; other site
765964003650	dimer interface [polypeptide binding]; other site
765964003651	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
765964003652	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
765964003653	Ligand Binding Site [chemical binding]; other site
765964003654	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
765964003655	HSP70 interaction site [polypeptide binding]; other site
765964003656	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
765964003657	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
765964003658	active site
765964003659	(T/H)XGH motif; other site
765964003660	nickel responsive regulator; Provisional; Region: PRK00630
765964003661	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
765964003662	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
765964003663	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
765964003664	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
765964003665	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
765964003666	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
765964003667	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
765964003668	potential frameshift: common BLAST hit: gi|15645955|ref|NP_208134.1| outer membrane protein (omp29)
765964003669	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
765964003670	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
765964003671	Mg2+ transporter Helicobacter pylori CorA-like subgroup; Region: HpCorA-like; cd12836
765964003672	Cl binding site [ion binding]; other site
765964003673	oligomer interface [polypeptide binding]; other site
765964003674	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
765964003675	Phosphoglycerate kinase; Region: PGK; pfam00162
765964003676	substrate binding site [chemical binding]; other site
765964003677	hinge regions; other site
765964003678	ADP binding site [chemical binding]; other site
765964003679	catalytic site [active]
765964003680	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
765964003681	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
765964003682	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
765964003683	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
765964003684	ligand binding site [chemical binding]; other site
765964003685	active site
765964003686	UGI interface [polypeptide binding]; other site
765964003687	catalytic site [active]
765964003688	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
765964003689	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
765964003690	putative acyl-acceptor binding pocket; other site
765964003691	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
765964003692	C-terminal peptidase (prc); Region: prc; TIGR00225
765964003693	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
765964003694	protein binding site [polypeptide binding]; other site
765964003695	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
765964003696	Catalytic dyad [active]
765964003697	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
765964003698	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964003699	Predicted helicase [General function prediction only]; Region: COG4889
765964003700	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK05848
765964003701	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
765964003702	dimerization interface [polypeptide binding]; other site
765964003703	active site
765964003704	Quinolinate synthetase A protein; Region: NadA; cl00420
765964003705	phosphatidylserine decarboxylase; Provisional; Region: PRK03934
765964003706	prenyltransferase; Reviewed; Region: ubiA; PRK12874
765964003707	UbiA prenyltransferase family; Region: UbiA; pfam01040
765964003708	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
765964003709	Competence protein; Region: Competence; pfam03772
765964003710	replicative DNA helicase; Provisional; Region: PRK08506
765964003711	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
765964003712	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
765964003713	Walker A motif; other site
765964003714	ATP binding site [chemical binding]; other site
765964003715	Walker B motif; other site
765964003716	DNA binding loops [nucleotide binding]
765964003717	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
765964003718	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
765964003719	putative substrate binding site [chemical binding]; other site
765964003720	putative ATP binding site [chemical binding]; other site
765964003721	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
765964003722	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
765964003723	dimer interface [polypeptide binding]; other site
765964003724	phosphorylation site [posttranslational modification]
765964003725	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
765964003726	ATP binding site [chemical binding]; other site
765964003727	Mg2+ binding site [ion binding]; other site
765964003728	G-X-G motif; other site
765964003729	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
765964003730	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
765964003731	active site
765964003732	phosphorylation site [posttranslational modification]
765964003733	intermolecular recognition site; other site
765964003734	dimerization interface [polypeptide binding]; other site
765964003735	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
765964003736	DNA binding site [nucleotide binding]
765964003737	potential frameshift: common BLAST hit: gi|383750410|ref|YP_005425513.1| type IIS restriction enzyme M1 protein (mod)
765964003738	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
765964003739	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964003740	DNA methylase; Region: N6_N4_Mtase; cl17433
765964003741	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
765964003742	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964003743	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
765964003744	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964003745	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
765964003746	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964003747	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
765964003748	DEAD-like helicases superfamily; Region: DEXDc; smart00487
765964003749	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
765964003750	rod shape-determining protein MreC; Region: MreC; pfam04085
765964003751	rod shape-determining protein MreB; Provisional; Region: PRK13927
765964003752	MreB and similar proteins; Region: MreB_like; cd10225
765964003753	nucleotide binding site [chemical binding]; other site
765964003754	Mg binding site [ion binding]; other site
765964003755	putative protofilament interaction site [polypeptide binding]; other site
765964003756	RodZ interaction site [polypeptide binding]; other site
765964003757	endopeptidase Clp ATP-binding regulatory subunit (clpX); Region: clpX; TIGR00382
765964003758	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
765964003759	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
765964003760	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964003761	Walker A motif; other site
765964003762	ATP binding site [chemical binding]; other site
765964003763	Walker B motif; other site
765964003764	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
765964003765	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
765964003766	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
765964003767	active site
765964003768	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
765964003769	flagellar assembly protein FliW; Provisional; Region: PRK13282
765964003770	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
765964003771	ATP-dependent protease La; Region: lon; TIGR00763
765964003772	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964003773	Walker A motif; other site
765964003774	ATP binding site [chemical binding]; other site
765964003775	Walker B motif; other site
765964003776	arginine finger; other site
765964003777	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
765964003778	prephenate dehydrogenase; Validated; Region: PRK08507
765964003779	Prephenate dehydrogenase; Region: PDH; pfam02153
765964003780	DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism]; Region: NUC1; COG1864
765964003781	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
765964003782	active site
765964003783	substrate binding site [chemical binding]; other site
765964003784	Mg2+ binding site [ion binding]; other site
765964003785	Type III restriction/modification enzyme methylation subunit; Region: TypeIII_RM_meth; pfam12564
765964003786	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
765964003787	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964003788	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964003789	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3421
765964003790	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
765964003791	ATP binding site [chemical binding]; other site
765964003792	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
765964003793	putative Mg++ binding site [ion binding]; other site
765964003794	biotin synthase; Provisional; Region: PRK08508
765964003795	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
765964003796	FeS/SAM binding site; other site
765964003797	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
765964003798	YihY family inner membrane protein; Region: yihY_not_rbn; TIGR00765
765964003799	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_4; pfam14281
765964003800	7-cyano-7-deazaguanine reductase; Region: QueF-II; TIGR03139
765964003801	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
765964003802	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
765964003803	IPP transferase; Region: IPPT; pfam01715
765964003804	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
765964003805	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
765964003806	Ligand binding site; other site
765964003807	metal-binding site
765964003808	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13904
765964003809	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
765964003810	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
765964003811	flagellum-specific ATP synthase; Validated; Region: fliI; PRK08472
765964003812	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
765964003813	Walker A motif/ATP binding site; other site
765964003814	Walker B motif; other site
765964003815	Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis [Cell motility and secretion / Intracellular trafficking and secretion]; Region: VirB11; COG0630
765964003816	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
765964003817	ATP binding site [chemical binding]; other site
765964003818	Walker A motif; other site
765964003819	hexamer interface [polypeptide binding]; other site
765964003820	Walker B motif; other site
765964003821	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
765964003822	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
765964003823	active site
765964003824	HIGH motif; other site
765964003825	nucleotide binding site [chemical binding]; other site
765964003826	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
765964003827	active site
765964003828	KMSKS motif; other site
765964003829	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
765964003830	tRNA binding surface [nucleotide binding]; other site
765964003831	anticodon binding site; other site
765964003832	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
765964003833	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
765964003834	RNA binding surface [nucleotide binding]; other site
765964003835	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14462
765964003836	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
765964003837	FeS/SAM binding site; other site
765964003838	KpsF/GutQ family protein; Region: kpsF; TIGR00393
765964003839	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
765964003840	putative active site [active]
765964003841	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
765964003842	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
765964003843	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
765964003844	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
765964003845	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
765964003846	dimethyladenosine transferase; Region: ksgA; TIGR00755
765964003847	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
765964003848	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
765964003849	formyltetrahydrofolate deformylase; Region: PurU; TIGR00655
765964003850	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
765964003851	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
765964003852	active site
765964003853	substrate binding site [chemical binding]; other site
765964003854	cosubstrate binding site; other site
765964003855	catalytic site [active]
765964003856	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
765964003857	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
765964003858	tandem repeat interface [polypeptide binding]; other site
765964003859	oligomer interface [polypeptide binding]; other site
765964003860	active site residues [active]
765964003861	TIR domain; Region: TIR_2; cl17458
765964003862	heat shock 70 kDa protein; Provisional; Region: PTZ00009
765964003863	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
765964003864	active site
765964003865	carbon storage regulator; Provisional; Region: PRK00568
765964003866	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK04181
765964003867	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
765964003868	SmpB-tmRNA interface; other site
765964003869	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
765964003870	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
765964003871	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
765964003872	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
765964003873	ribonuclease P protein component, eubacterial; Region: rnpA; TIGR00188
765964003874	hypothetical protein; Provisional; Region: PRK14374
765964003875	membrane protein insertase; Provisional; Region: PRK01318
765964003876	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
765964003877	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
765964003878	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
765964003879	tRNA modification GTPase TrmE; Region: mnmE_trmE_thdF; TIGR00450
765964003880	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
765964003881	GTP/Mg2+ binding site [chemical binding]; other site
765964003882	G4 box; other site
765964003883	G5 box; other site
765964003884	trmE is a tRNA modification GTPase; Region: trmE; cd04164
765964003885	G1 box; other site
765964003886	G1 box; other site
765964003887	GTP/Mg2+ binding site [chemical binding]; other site
765964003888	Switch I region; other site
765964003889	Switch I region; other site
765964003890	G2 box; other site
765964003891	G2 box; other site
765964003892	Switch II region; other site
765964003893	G3 box; other site
765964003894	G3 box; other site
765964003895	Switch II region; other site
765964003896	G4 box; other site
765964003897	G5 box; other site
765964003898	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
765964003899	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964003900	LPP20 lipoprotein; Region: LPP20; pfam02169
765964003901	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
765964003902	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
765964003903	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
765964003904	catalytic residues [active]
765964003905	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
765964003906	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
765964003907	RNA binding surface [nucleotide binding]; other site
765964003908	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
765964003909	active site
765964003910	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
765964003911	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
765964003912	active site
765964003913	PHP Thumb interface [polypeptide binding]; other site
765964003914	metal binding site [ion binding]; metal-binding site
765964003915	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
765964003916	generic binding surface I; other site
765964003917	generic binding surface II; other site
765964003918	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
765964003919	Heat shock protein [Posttranslational modification, protein turnover, chaperones]; Region: HslJ; COG3187
765964003920	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
765964003921	mce related protein; Region: MCE; pfam02470
765964003922	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
765964003923	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
765964003924	Walker A/P-loop; other site
765964003925	ATP binding site [chemical binding]; other site
765964003926	Q-loop/lid; other site
765964003927	ABC transporter signature motif; other site
765964003928	Walker B; other site
765964003929	D-loop; other site
765964003930	H-loop/switch region; other site
765964003931	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
765964003932	conserved hypothetical integral membrane protein; Region: TIGR00056
765964003933	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964003934	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
765964003935	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
765964003936	homodimer interface [polypeptide binding]; other site
765964003937	substrate-cofactor binding pocket; other site
765964003938	catalytic residue [active]
765964003939	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964003940	DNA polymerase I; Region: pola; TIGR00593
765964003941	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
765964003942	active site
765964003943	metal binding site 1 [ion binding]; metal-binding site
765964003944	putative 5' ssDNA interaction site; other site
765964003945	metal binding site 3; metal-binding site
765964003946	metal binding site 2 [ion binding]; metal-binding site
765964003947	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
765964003948	putative DNA binding site [nucleotide binding]; other site
765964003949	putative metal binding site [ion binding]; other site
765964003950	3'-5' exonuclease; Region: 35EXOc; smart00474
765964003951	active site
765964003952	substrate binding site [chemical binding]; other site
765964003953	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
765964003954	active site
765964003955	DNA binding site [nucleotide binding]
765964003956	catalytic site [active]
765964003957	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
765964003958	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
765964003959	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
765964003960	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
765964003961	thymidylate kinase; Validated; Region: tmk; PRK00698
765964003962	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
765964003963	TMP-binding site; other site
765964003964	ATP-binding site [chemical binding]; other site
765964003965	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
765964003966	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
765964003967	active site
765964003968	(T/H)XGH motif; other site
765964003969	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
765964003970	Flavoprotein; Region: Flavoprotein; pfam02441
765964003971	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK08515
765964003972	flagella basal body P-ring formation protein FlgA; Region: flgA_cterm; TIGR03170
765964003973	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
765964003974	Part of AAA domain; Region: AAA_19; pfam13245
765964003975	Family description; Region: UvrD_C_2; pfam13538
765964003976	TPR repeat; Region: TPR_11; pfam13414
765964003977	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
765964003978	TPR motif; other site
765964003979	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
765964003980	binding surface
765964003981	TPR motif; other site
765964003982	seryl-tRNA synthetase; Provisional; Region: PRK05431
765964003983	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
765964003984	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
765964003985	dimer interface [polypeptide binding]; other site
765964003986	active site
765964003987	motif 1; other site
765964003988	motif 2; other site
765964003989	motif 3; other site
765964003990	Predicted amidohydrolase [General function prediction only]; Region: COG0388
765964003991	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
765964003992	active site
765964003993	catalytic triad [active]
765964003994	dimer interface [polypeptide binding]; other site
765964003995	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK14065
765964003996	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
765964003997	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
765964003998	S-adenosylmethionine binding site [chemical binding]; other site
765964003999	Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863
765964004000	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
765964004001	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
765964004002	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
765964004003	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
765964004004	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
765964004005	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
765964004006	HlyD family secretion protein; Region: HlyD_3; pfam13437
765964004007	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
765964004008	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
765964004009	Domain of unknown function DUF21; Region: DUF21; pfam01595
765964004010	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
765964004011	Transporter associated domain; Region: CorC_HlyC; smart01091
765964004012	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
765964004013	Phosphate transporter family; Region: PHO4; pfam01384
765964004014	Phosphate transporter family; Region: PHO4; cl00396
765964004015	NifU-like domain; Region: NifU; pfam01106
765964004016	UDP-N-acetylmuramyl-tripeptide synthetase; Region: murE; TIGR01085
765964004017	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
765964004018	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
765964004019	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
765964004020	putative active site [active]
765964004021	transaldolase; Provisional; Region: PRK03903
765964004022	catalytic residue [active]
765964004023	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
765964004024	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
765964004025	5S rRNA interface [nucleotide binding]; other site
765964004026	CTC domain interface [polypeptide binding]; other site
765964004027	L16 interface [polypeptide binding]; other site
765964004028	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
765964004029	putative active site [active]
765964004030	catalytic residue [active]
765964004031	Predicted permeases [General function prediction only]; Region: COG0795
765964004032	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
765964004033	Catalytic domain of type II restriction endonucleases BfiI and NgoFVII, and uncharacterized proteins with a DEAD domain; Region: PLDc_Bfil_DEXD_like; cd09117
765964004034	PLD-like domain; Region: PLDc_2; pfam13091
765964004035	homodimer interface [polypeptide binding]; other site
765964004036	putative active site [active]
765964004037	catalytic site [active]
765964004038	Uncharacterized conserved protein (DUF2161); Region: DUF2161; cl02298
765964004039	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964004040	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3399
765964004041	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
765964004042	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
765964004043	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
765964004044	metal-binding site [ion binding]
765964004045	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
765964004046	Soluble P-type ATPase [General function prediction only]; Region: COG4087
765964004047	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
765964004048	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
765964004049	S-adenosylmethionine binding site [chemical binding]; other site
765964004050	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
765964004051	catalytic motif [active]
765964004052	Zn binding site [ion binding]; other site
765964004053	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
765964004054	RibD C-terminal domain; Region: RibD_C; cl17279
765964004055	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
765964004056	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
765964004057	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
765964004058	NAD(P) binding pocket [chemical binding]; other site
765964004059	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
765964004060	4Fe-4S binding domain; Region: Fer4_5; pfam12801
765964004061	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
765964004062	acyl-phosphate glycerol 3-phosphate acyltransferase; Region: TIGR00023
765964004063	FolB domain; Region: folB_dom; TIGR00526
765964004064	active site
765964004065	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
765964004066	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
765964004067	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
765964004068	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
765964004069	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
765964004070	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
765964004071	transcription elongation factor NusA; Provisional; Region: nusA; PRK12328
765964004072	NusA N-terminal domain; Region: NusA_N; pfam08529
765964004073	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
765964004074	RNA binding site [nucleotide binding]; other site
765964004075	homodimer interface [polypeptide binding]; other site
765964004076	NusA-like KH domain; Region: KH_5; pfam13184
765964004077	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
765964004078	G-X-X-G motif; other site
765964004079	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
765964004080	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
765964004081	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
765964004082	Restriction endonuclease [Defense mechanisms]; Region: COG3587
765964004083	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
765964004084	ATP binding site [chemical binding]; other site
765964004085	putative Mg++ binding site [ion binding]; other site
765964004086	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
765964004087	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
765964004088	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964004089	DNA methylase; Region: N6_N4_Mtase; pfam01555
765964004090	ATP-dependent DNA helicase RecG; Region: recG; TIGR00643
765964004091	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
765964004092	ssDNA binding site; other site
765964004093	generic binding surface II; other site
765964004094	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
765964004095	ATP binding site [chemical binding]; other site
765964004096	putative Mg++ binding site [ion binding]; other site
765964004097	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
765964004098	nucleotide binding region [chemical binding]; other site
765964004099	ATP-binding site [chemical binding]; other site
765964004100	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964004101	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
765964004102	active site
765964004103	putative catalytic site [active]
765964004104	DNA binding site [nucleotide binding]
765964004105	putative phosphate binding site [ion binding]; other site
765964004106	metal binding site A [ion binding]; metal-binding site
765964004107	AP binding site [nucleotide binding]; other site
765964004108	metal binding site B [ion binding]; metal-binding site
765964004109	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
765964004110	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
765964004111	Walker A motif; other site
765964004112	ATP binding site [chemical binding]; other site
765964004113	Walker B motif; other site
765964004114	arginine finger; other site
765964004115	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
765964004116	DnaA box-binding interface [nucleotide binding]; other site
765964004117	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
765964004118	Protein of unknown function (DUF2443); Region: DUF2443; pfam10398
765964004119	glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Region: glmS; TIGR01135
765964004120	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
765964004121	glutaminase active site [active]
765964004122	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
765964004123	dimer interface [polypeptide binding]; other site
765964004124	active site
765964004125	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
765964004126	dimer interface [polypeptide binding]; other site
765964004127	active site
765964004128	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
765964004129	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
765964004130	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
765964004131	Abi-like protein; Region: Abi_2; cl01988
765964004132	potential frameshift: common BLAST hit: gi|188528306|ref|YP_001910993.1| type I restriction enzyme M protein (hsdM)
765964004133	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
765964004134	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
765964004135	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
765964004136	ATP binding site [chemical binding]; other site
765964004137	putative Mg++ binding site [ion binding]; other site
765964004138	Protein of unknown function DUF45; Region: DUF45; pfam01863
765964004139	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
765964004140	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
765964004141	N-terminal plug; other site
765964004142	ligand-binding site [chemical binding]; other site
765964004143	Arginase family; Region: Arginase; cd09989
765964004144	active site
765964004145	Mn binding site [ion binding]; other site
765964004146	oligomer interface [polypeptide binding]; other site
765964004147	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
765964004148	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
765964004149	hexamer interface [polypeptide binding]; other site
765964004150	ligand binding site [chemical binding]; other site
765964004151	putative active site [active]
765964004152	NAD(P) binding site [chemical binding]; other site
765964004153	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
765964004154	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
765964004155	ATP-NAD kinase; Region: NAD_kinase; pfam01513
765964004156	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
765964004157	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
765964004158	Walker A/P-loop; other site
765964004159	ATP binding site [chemical binding]; other site
765964004160	Q-loop/lid; other site
765964004161	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
765964004162	ABC transporter signature motif; other site
765964004163	Walker B; other site
765964004164	D-loop; other site
765964004165	H-loop/switch region; other site
765964004166	Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293
765964004167	Domain of unknown function (DUF814); Region: DUF814; pfam05670
765964004168	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
765964004169	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cd04761
765964004170	DNA binding residues [nucleotide binding]
765964004171	Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of...; Region: SR_IS607_transposase_like; cd03769
765964004172	catalytic residues [active]
765964004173	catalytic nucleophile [active]
765964004174	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
765964004175	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
765964004176	Probable transposase; Region: OrfB_IS605; pfam01385
765964004177	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
765964004178	DNA polymerase III subunit epsilon; Provisional; Region: PRK08517
765964004179	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
765964004180	active site
765964004181	catalytic site [active]
765964004182	substrate binding site [chemical binding]; other site
765964004183	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
765964004184	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
765964004185	substrate binding site [chemical binding]; other site
765964004186	hexamer interface [polypeptide binding]; other site
765964004187	metal binding site [ion binding]; metal-binding site
765964004188	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
765964004189	active site
765964004190	Methyltransferase domain; Region: Methyltransf_26; pfam13659
765964004191	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
765964004192	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
765964004193	cofactor binding site; other site
765964004194	DNA binding site [nucleotide binding]
765964004195	substrate interaction site [chemical binding]; other site
765964004196	elongation factor Ts; Provisional; Region: tsf; PRK09377
765964004197	UBA/TS-N domain; Region: UBA; pfam00627
765964004198	Elongation factor TS; Region: EF_TS; pfam00889
765964004199	Elongation factor TS; Region: EF_TS; pfam00889
765964004200	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
765964004201	rRNA interaction site [nucleotide binding]; other site
765964004202	S8 interaction site; other site
765964004203	putative laminin-1 binding site; other site
765964004204	Part of AAA domain; Region: AAA_19; pfam13245
765964004205	putative recombination protein RecB; Provisional; Region: PRK13909
765964004206	Family description; Region: UvrD_C_2; pfam13538
765964004207	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
765964004208	pH-dependent sodium/proton antiporter; Provisional; Region: nhaA; PRK14856
765964004209	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
765964004210	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
765964004211	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
765964004212	protein-export membrane protein SecF; Region: 3a0501s07; TIGR00966
765964004213	Protein export membrane protein; Region: SecD_SecF; pfam02355
765964004214	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
765964004215	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
765964004216	HIGH motif; other site
765964004217	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
765964004218	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
765964004219	active site
765964004220	KMSKS motif; other site
765964004221	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
765964004222	tRNA binding surface [nucleotide binding]; other site
765964004223	Lipopolysaccharide-assembly; Region: LptE; pfam04390
765964004224	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
765964004225	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
765964004226	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
765964004227	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
765964004228	Peptidase family M23; Region: Peptidase_M23; pfam01551
765964004229	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
765964004230	Peptidase family M23; Region: Peptidase_M23; pfam01551
765964004231	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
765964004232	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
765964004233	transcription-repair coupling factor (mfd); Region: mfd; TIGR00580
765964004234	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
765964004235	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
765964004236	ATP binding site [chemical binding]; other site
765964004237	putative Mg++ binding site [ion binding]; other site
765964004238	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
765964004239	nucleotide binding region [chemical binding]; other site
765964004240	ATP-binding site [chemical binding]; other site
765964004241	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
765964004242	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
765964004243	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
765964004244	iron-sulfur cluster [ion binding]; other site
765964004245	[2Fe-2S] cluster binding site [ion binding]; other site
765964004246	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
765964004247	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
765964004248	intrachain domain interface; other site
765964004249	interchain domain interface [polypeptide binding]; other site
765964004250	heme bH binding site [chemical binding]; other site
765964004251	Qi binding site; other site
765964004252	heme bL binding site [chemical binding]; other site
765964004253	Qo binding site; other site
765964004254	interchain domain interface [polypeptide binding]; other site
765964004255	intrachain domain interface; other site
765964004256	Qi binding site; other site
765964004257	Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032
765964004258	Qo binding site; other site
765964004259	Cytochrome c1 [Energy production and conversion]; Region: CYT1; COG2857
765964004260	Cytochrome c; Region: Cytochrom_C; pfam00034
765964004261	Cytochrome c; Region: Cytochrom_C; cl11414
765964004262	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
765964004263	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
765964004264	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
765964004265	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK03907
765964004266	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
765964004267	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
765964004268	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
765964004269	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
765964004270	Cell cycle protein; Region: FTSW_RODA_SPOVE; pfam01098
765964004271	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
765964004272	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
765964004273	putative ligand binding site [chemical binding]; other site
765964004274	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
765964004275	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
765964004276	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
765964004277	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
765964004278	dimer interface [polypeptide binding]; other site
765964004279	decamer (pentamer of dimers) interface [polypeptide binding]; other site
765964004280	catalytic triad [active]
765964004281	peroxidatic and resolving cysteines [active]
765964004282	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
765964004283	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
765964004284	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
765964004285	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
765964004286	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
765964004287	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
765964004288	G1 box; other site
765964004289	GTP/Mg2+ binding site [chemical binding]; other site
765964004290	Switch I region; other site
765964004291	G2 box; other site
765964004292	G3 box; other site
765964004293	Switch II region; other site
765964004294	G4 box; other site
765964004295	G5 box; other site
765964004296	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
765964004297	OstA-like protein; Region: OstA; pfam03968
765964004298	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
765964004299	motif II; other site
765964004300	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
765964004301	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
765964004302	Sporulation related domain; Region: SPOR; pfam05036
765964004303	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
765964004304	N-acetyl-D-glucosamine binding site [chemical binding]; other site
765964004305	catalytic residue [active]
765964004306	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
765964004307	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
765964004308	active site
765964004309	riboflavin synthase, alpha subunit; Region: ribE; TIGR00187
765964004310	Lumazine binding domain; Region: Lum_binding; pfam00677
765964004311	Lumazine binding domain; Region: Lum_binding; pfam00677
765964004312	flhB C-terminus-related protein; Region: flhB_rel; TIGR00789
765964004313	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
765964004314	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
765964004315	Walker A/P-loop; other site
765964004316	ATP binding site [chemical binding]; other site
765964004317	Q-loop/lid; other site
765964004318	ABC transporter signature motif; other site
765964004319	Walker B; other site
765964004320	D-loop; other site
765964004321	H-loop/switch region; other site
765964004322	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
765964004323	NIL domain; Region: NIL; pfam09383
765964004324	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
765964004325	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
765964004326	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
765964004327	active site
765964004328	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
765964004329	This subfamily is composed of uncharacterized bacterial glycosyltransferases in the MraY-like family. This family contains both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases, which...; Region: GT_MraY_like; cd06912
765964004330	Mg++ binding site [ion binding]; other site
765964004331	putative catalytic motif [active]
765964004332	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
765964004333	active site
765964004334	hydrophilic channel; other site
765964004335	dimerization interface [polypeptide binding]; other site
765964004336	catalytic residues [active]
765964004337	active site lid [active]
765964004338	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
765964004339	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK03946
765964004340	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
765964004341	metallohydrolase, glycoprotease/Kae1 family; Region: gcp_kae1; TIGR00329
765964004342	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
765964004343	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
765964004344	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
765964004345	hypothetical protein; Provisional; Region: PRK10236
765964004346	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
765964004347	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735