-- dump date   	20140619_113142
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
866344000001	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
866344000002	putative RNA binding site [nucleotide binding]; other site
866344000003	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
866344000004	homopentamer interface [polypeptide binding]; other site
866344000005	active site
866344000006	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
866344000007	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA; cl00391
866344000008	active site clefts [active]
866344000009	zinc binding site [ion binding]; other site
866344000010	dimer interface [polypeptide binding]; other site
866344000011	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
866344000012	active site
866344000013	dimer interface [polypeptide binding]; other site
866344000014	pantoate--beta-alanine ligase; Region: panC; TIGR00018
866344000015	Pantoate-beta-alanine ligase; Region: PanC; cd00560
866344000016	active site
866344000017	ATP-binding site [chemical binding]; other site
866344000018	pantoate-binding site; other site
866344000019	HXXH motif; other site
866344000020	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344000021	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
866344000022	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
866344000023	ring oligomerisation interface [polypeptide binding]; other site
866344000024	ATP/Mg binding site [chemical binding]; other site
866344000025	stacking interactions; other site
866344000026	hinge regions; other site
866344000027	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
866344000028	oligomerisation interface [polypeptide binding]; other site
866344000029	mobile loop; other site
866344000030	roof hairpin; other site
866344000031	DNA primase, catalytic core; Region: dnaG; TIGR01391
866344000032	CHC2 zinc finger; Region: zf-CHC2; pfam01807
866344000033	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
866344000034	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
866344000035	active site
866344000036	metal binding site [ion binding]; metal-binding site
866344000037	interdomain interaction site; other site
866344000038	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
866344000039	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
866344000040	Ligand Binding Site [chemical binding]; other site
866344000041	TrbC/VIRB2 family; Region: TrbC; cl01583
866344000042	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
866344000043	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
866344000044	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
866344000045	Walker A motif; other site
866344000046	ATP binding site [chemical binding]; other site
866344000047	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
866344000048	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
866344000049	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
866344000050	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
866344000051	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866344000052	active site
866344000053	phosphorylation site [posttranslational modification]
866344000054	intermolecular recognition site; other site
866344000055	dimerization interface [polypeptide binding]; other site
866344000056	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
866344000057	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
866344000058	dimer interface [polypeptide binding]; other site
866344000059	active site
866344000060	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866344000061	catalytic residues [active]
866344000062	substrate binding site [chemical binding]; other site
866344000063	lipid A 1-phosphatase; Reviewed; Region: PRK09597
866344000064	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
866344000065	active site
866344000066	lipid A phosphoethanolamine transferase; Reviewed; Region: PRK09598
866344000067	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
866344000068	Sulfatase; Region: Sulfatase; pfam00884
866344000069	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344000070	DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism]; Region: NUC1; COG1864
866344000071	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
866344000072	prephenate dehydrogenase; Validated; Region: PRK08507
866344000073	Prephenate dehydrogenase; Region: PDH; pfam02153
866344000074	ATP-dependent protease La; Region: lon; TIGR00763
866344000075	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344000076	Walker A motif; other site
866344000077	ATP binding site [chemical binding]; other site
866344000078	Walker B motif; other site
866344000079	arginine finger; other site
866344000080	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
866344000081	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
866344000082	flagellar assembly protein FliW; Provisional; Region: PRK13282
866344000083	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
866344000084	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
866344000085	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
866344000086	active site
866344000087	endopeptidase Clp ATP-binding regulatory subunit (clpX); Region: clpX; TIGR00382
866344000088	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
866344000089	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
866344000090	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344000091	Walker A motif; other site
866344000092	ATP binding site [chemical binding]; other site
866344000093	Walker B motif; other site
866344000094	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
866344000095	rod shape-determining protein MreB; Provisional; Region: PRK13927
866344000096	MreB and similar proteins; Region: MreB_like; cd10225
866344000097	nucleotide binding site [chemical binding]; other site
866344000098	Mg binding site [ion binding]; other site
866344000099	putative protofilament interaction site [polypeptide binding]; other site
866344000100	RodZ interaction site [polypeptide binding]; other site
866344000101	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
866344000102	rod shape-determining protein MreC; Region: MreC; pfam04085
866344000103	DEAD-like helicases superfamily; Region: DEXDc; smart00487
866344000104	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
866344000105	ATP binding site [chemical binding]; other site
866344000106	putative Mg++ binding site [ion binding]; other site
866344000107	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
866344000108	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344000109	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
866344000110	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866344000111	active site
866344000112	phosphorylation site [posttranslational modification]
866344000113	intermolecular recognition site; other site
866344000114	dimerization interface [polypeptide binding]; other site
866344000115	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866344000116	DNA binding site [nucleotide binding]
866344000117	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
866344000118	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
866344000119	dimer interface [polypeptide binding]; other site
866344000120	phosphorylation site [posttranslational modification]
866344000121	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866344000122	ATP binding site [chemical binding]; other site
866344000123	Mg2+ binding site [ion binding]; other site
866344000124	G-X-G motif; other site
866344000125	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
866344000126	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
866344000127	putative substrate binding site [chemical binding]; other site
866344000128	putative ATP binding site [chemical binding]; other site
866344000129	replicative DNA helicase; Provisional; Region: PRK08506
866344000130	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
866344000131	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
866344000132	Walker A motif; other site
866344000133	ATP binding site [chemical binding]; other site
866344000134	Walker B motif; other site
866344000135	DNA binding loops [nucleotide binding]
866344000136	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
866344000137	Competence protein; Region: Competence; pfam03772
866344000138	prenyltransferase; Reviewed; Region: ubiA; PRK12874
866344000139	UbiA prenyltransferase family; Region: UbiA; pfam01040
866344000140	phosphatidylserine decarboxylase; Provisional; Region: PRK03934
866344000141	Quinolinate synthetase A protein; Region: NadA; cl00420
866344000142	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK05848
866344000143	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
866344000144	dimerization interface [polypeptide binding]; other site
866344000145	active site
866344000146	Predicted helicase [General function prediction only]; Region: COG4889
866344000147	Predicted helicase [General function prediction only]; Region: COG4889
866344000148	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866344000149	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344000150	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
866344000151	C-terminal peptidase (prc); Region: prc; TIGR00225
866344000152	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
866344000153	protein binding site [polypeptide binding]; other site
866344000154	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
866344000155	Catalytic dyad [active]
866344000156	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
866344000157	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
866344000158	putative acyl-acceptor binding pocket; other site
866344000159	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
866344000160	ligand binding site [chemical binding]; other site
866344000161	active site
866344000162	UGI interface [polypeptide binding]; other site
866344000163	catalytic site [active]
866344000164	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
866344000165	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
866344000166	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
866344000167	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
866344000168	Phosphoglycerate kinase; Region: PGK; pfam00162
866344000169	substrate binding site [chemical binding]; other site
866344000170	hinge regions; other site
866344000171	ADP binding site [chemical binding]; other site
866344000172	catalytic site [active]
866344000173	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
866344000174	Mg2+ transporter Helicobacter pylori CorA-like subgroup; Region: HpCorA-like; cd12836
866344000175	Cl binding site [ion binding]; other site
866344000176	oligomer interface [polypeptide binding]; other site
866344000177	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
866344000178	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866344000179	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344000180	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
866344000181	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
866344000182	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
866344000183	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
866344000184	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
866344000185	DNA binding site [nucleotide binding]
866344000186	substrate interaction site [chemical binding]; other site
866344000187	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
866344000188	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
866344000189	Na binding site [ion binding]; other site
866344000190	Proline dehydrogenase; Region: Pro_dh; pfam01619
866344000191	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
866344000192	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
866344000193	Glutamate binding site [chemical binding]; other site
866344000194	NAD binding site [chemical binding]; other site
866344000195	catalytic residues [active]
866344000196	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
866344000197	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
866344000198	Proteins of 100 residues with WXG; Region: WXG100; cl02005
866344000199	A nuclease of the HNH/ENDO VII superfamily with conserved WHH; Region: WHH; pfam14414
866344000200	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
866344000201	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
866344000202	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
866344000203	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
866344000204	Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829
866344000205	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
866344000206	G1 box; other site
866344000207	GTP/Mg2+ binding site [chemical binding]; other site
866344000208	G2 box; other site
866344000209	Switch I region; other site
866344000210	G3 box; other site
866344000211	Switch II region; other site
866344000212	G4 box; other site
866344000213	G5 box; other site
866344000214	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
866344000215	UreF; Region: UreF; pfam01730
866344000216	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
866344000217	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
866344000218	dimer interface [polypeptide binding]; other site
866344000219	catalytic residues [active]
866344000220	AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293
866344000221	urease subunit beta; Provisional; Region: ureB; PRK13985
866344000222	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
866344000223	subunit interactions [polypeptide binding]; other site
866344000224	active site
866344000225	flap region; other site
866344000226	urease subunit alpha; Provisional; Region: PRK13986
866344000227	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
866344000228	alpha-gamma subunit interface [polypeptide binding]; other site
866344000229	beta-gamma subunit interface [polypeptide binding]; other site
866344000230	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
866344000231	gamma-beta subunit interface [polypeptide binding]; other site
866344000232	alpha-beta subunit interface [polypeptide binding]; other site
866344000233	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
866344000234	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14324
866344000235	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
866344000236	active site
866344000237	substrate binding site [chemical binding]; other site
866344000238	metal binding site [ion binding]; metal-binding site
866344000239	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
866344000240	peptide chain release factor 1; Validated; Region: prfA; PRK00591
866344000241	This domain is found in peptide chain release factors; Region: PCRF; smart00937
866344000242	RF-1 domain; Region: RF-1; pfam00472
866344000243	potential frameshift: common BLAST hit: gi|383749138|ref|YP_005424241.1| outer membrane protein (omp3)
866344000244	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344000245	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344000246	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
866344000247	dimer interface [polypeptide binding]; other site
866344000248	putative CheW interface [polypeptide binding]; other site
866344000249	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
866344000250	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
866344000251	23S rRNA interface [nucleotide binding]; other site
866344000252	L3 interface [polypeptide binding]; other site
866344000253	Predicted dehydrogenase [General function prediction only]; Region: COG0579
866344000254	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
866344000255	NLPC_P60 stabilising domain, N term; Region: N_NLPC_P60; pfam12912
866344000256	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
866344000257	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
866344000258	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
866344000259	NlpC/P60 family; Region: NLPC_P60; pfam00877
866344000260	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
866344000261	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
866344000262	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
866344000263	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
866344000264	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
866344000265	DNA binding residues [nucleotide binding]
866344000266	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
866344000267	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
866344000268	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
866344000269	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
866344000270	DpnII restriction endonuclease; Region: DpnII; pfam04556
866344000271	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866344000272	Methyltransferase domain; Region: Methyltransf_26; pfam13659
866344000273	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344000274	potential frameshift: common BLAST hit: gi|298736963|ref|YP_003729493.1| putative alpha(1,2)fucosyltransferase
866344000275	Alpha-1,2-fucosyltransferase; Region: Fut1_Fut2_like; cd11301
866344000276	GDP-Fucose binding site [chemical binding]; other site
866344000277	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
866344000278	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
866344000279	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
866344000280	putative ligand binding site [chemical binding]; other site
866344000281	putative NAD binding site [chemical binding]; other site
866344000282	catalytic site [active]
866344000283	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
866344000284	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
866344000285	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866344000286	catalytic residue [active]
866344000287	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
866344000288	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
866344000289	dimer interface [polypeptide binding]; other site
866344000290	putative CheW interface [polypeptide binding]; other site
866344000291	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases and ATP sulphurylases. The domain forms a apha/beta/apha fold which  binds to Adenosine group; Region: Alpha_ANH_like; cd01986
866344000292	Ligand Binding Site [chemical binding]; other site
866344000293	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344000294	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
866344000295	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
866344000296	metal-binding site
866344000297	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
866344000298	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
866344000299	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
866344000300	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
866344000301	dimer interface [polypeptide binding]; other site
866344000302	putative CheW interface [polypeptide binding]; other site
866344000303	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
866344000304	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
866344000305	active site
866344000306	metal binding site [ion binding]; metal-binding site
866344000307	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
866344000308	S-ribosylhomocysteinase; Provisional; Region: PRK02260
866344000309	cystathionine gamma-synthase/cystathionine beta-lyase; Validated; Region: PRK06176
866344000310	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
866344000311	homodimer interface [polypeptide binding]; other site
866344000312	substrate-cofactor binding pocket; other site
866344000313	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866344000314	catalytic residue [active]
866344000315	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
866344000316	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
866344000317	dimer interface [polypeptide binding]; other site
866344000318	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866344000319	catalytic residue [active]
866344000320	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
866344000321	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
866344000322	nucleotide binding site [chemical binding]; other site
866344000323	NEF interaction site [polypeptide binding]; other site
866344000324	SBD interface [polypeptide binding]; other site
866344000325	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
866344000326	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
866344000327	dimer interface [polypeptide binding]; other site
866344000328	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
866344000329	heat-inducible transcription repressor; Provisional; Region: PRK03911
866344000330	hypothetical protein; Provisional; Region: PRK05834
866344000331	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
866344000332	flagellin B; Provisional; Region: PRK13588
866344000333	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
866344000334	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
866344000335	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
866344000336	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
866344000337	DNA topoisomerase I; Validated; Region: PRK05582
866344000338	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
866344000339	active site
866344000340	interdomain interaction site; other site
866344000341	putative metal-binding site [ion binding]; other site
866344000342	nucleotide binding site [chemical binding]; other site
866344000343	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
866344000344	domain I; other site
866344000345	DNA binding groove [nucleotide binding]
866344000346	phosphate binding site [ion binding]; other site
866344000347	domain II; other site
866344000348	domain III; other site
866344000349	nucleotide binding site [chemical binding]; other site
866344000350	catalytic site [active]
866344000351	domain IV; other site
866344000352	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
866344000353	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
866344000354	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
866344000355	Fe-S oxidoreductases [Energy production and conversion]; Region: COG0731
866344000356	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866344000357	FeS/SAM binding site; other site
866344000358	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
866344000359	phosphoenolpyruvate synthase; Validated; Region: PRK06464
866344000360	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
866344000361	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
866344000362	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
866344000363	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
866344000364	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
866344000365	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
866344000366	active site
866344000367	dimer interface [polypeptide binding]; other site
866344000368	motif 1; other site
866344000369	motif 2; other site
866344000370	motif 3; other site
866344000371	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
866344000372	anticodon binding site; other site
866344000373	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
866344000374	translation initiation factor IF-3; Region: infC; TIGR00168
866344000375	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
866344000376	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
866344000377	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
866344000378	23S rRNA binding site [nucleotide binding]; other site
866344000379	L21 binding site [polypeptide binding]; other site
866344000380	L13 binding site [polypeptide binding]; other site
866344000381	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344000382	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
866344000383	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
866344000384	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
866344000385	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
866344000386	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
866344000387	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
866344000388	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroG; COG3200
866344000389	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
866344000390	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
866344000391	catalytic triad [active]
866344000392	Uncharacterized conserved protein [Function unknown]; Region: COG1556
866344000393	iron-sulfur cluster-binding protein; Region: TIGR00273
866344000394	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
866344000395	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
866344000396	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
866344000397	Cysteine-rich domain; Region: CCG; pfam02754
866344000398	Cysteine-rich domain; Region: CCG; pfam02754
866344000399	L-lactate transport; Region: lctP; TIGR00795
866344000400	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
866344000401	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
866344000402	L-lactate permease; Region: Lactate_perm; pfam02652
866344000403	DNA glycosylase MutY; Provisional; Region: PRK13910
866344000404	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
866344000405	minor groove reading motif; other site
866344000406	helix-hairpin-helix signature motif; other site
866344000407	substrate binding pocket [chemical binding]; other site
866344000408	active site
866344000409	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
866344000410	DNA binding and oxoG recognition site [nucleotide binding]
866344000411	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
866344000412	Sodium:sulfate symporter transmembrane region; Region: Na_sulph_symp; pfam00939
866344000413	transmembrane helices; other site
866344000414	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
866344000415	Low-spin heme binding site [chemical binding]; other site
866344000416	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
866344000417	D-pathway; other site
866344000418	Putative water exit pathway; other site
866344000419	Binuclear center (active site) [active]
866344000420	K-pathway; other site
866344000421	Putative proton exit pathway; other site
866344000422	Cbb3-type cytochrome oxidase, cytochrome c subunit [Energy production and conversion]; Region: CcoO; COG2993
866344000423	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; cl01130
866344000424	cytochrome c oxidase, cbb3-type, CcoQ subunit, epsilon-Proteobacterial; Region: cbb3_Q_epsi; TIGR02736
866344000425	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
866344000426	Cytochrome c; Region: Cytochrom_C; pfam00034
866344000427	Cytochrome c; Region: Cytochrom_C; pfam00034
866344000428	Family of unknown function (DUF4006); Region: DUF4006; pfam13179
866344000429	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
866344000430	recombinase A; Provisional; Region: recA; PRK09354
866344000431	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
866344000432	hexamer interface [polypeptide binding]; other site
866344000433	Walker A motif; other site
866344000434	ATP binding site [chemical binding]; other site
866344000435	Walker B motif; other site
866344000436	enolase; Provisional; Region: eno; PRK00077
866344000437	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
866344000438	dimer interface [polypeptide binding]; other site
866344000439	metal binding site [ion binding]; metal-binding site
866344000440	substrate binding pocket [chemical binding]; other site
866344000441	AMIN domain; Region: AMIN; pfam11741
866344000442	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
866344000443	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
866344000444	ADP binding site [chemical binding]; other site
866344000445	magnesium binding site [ion binding]; other site
866344000446	putative shikimate binding site; other site
866344000447	Cache domain; Region: Cache_1; pfam02743
866344000448	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
866344000449	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
866344000450	Ligand binding site; other site
866344000451	metal-binding site
866344000452	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866344000453	Sel1-like repeats; Region: SEL1; smart00671
866344000454	Sel1-like repeats; Region: SEL1; smart00671
866344000455	Sel1-like repeats; Region: SEL1; smart00671
866344000456	Sel1-like repeats; Region: SEL1; smart00671
866344000457	Sel1-like repeats; Region: SEL1; smart00671
866344000458	hypothetical protein; Provisional; Region: PRK12378
866344000459	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
866344000460	dimer interface [polypeptide binding]; other site
866344000461	active site
866344000462	Schiff base residues; other site
866344000463	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
866344000464	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
866344000465	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866344000466	dimer interface [polypeptide binding]; other site
866344000467	phosphorylation site [posttranslational modification]
866344000468	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866344000469	ATP binding site [chemical binding]; other site
866344000470	Mg2+ binding site [ion binding]; other site
866344000471	G-X-G motif; other site
866344000472	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
866344000473	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866344000474	active site
866344000475	phosphorylation site [posttranslational modification]
866344000476	intermolecular recognition site; other site
866344000477	dimerization interface [polypeptide binding]; other site
866344000478	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866344000479	DNA binding site [nucleotide binding]
866344000480	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
866344000481	Peptidase family U32; Region: Peptidase_U32; pfam01136
866344000482	peptide chain release factor 2; Region: prfB; TIGR00020
866344000483	This domain is found in peptide chain release factors; Region: PCRF; smart00937
866344000484	RF-1 domain; Region: RF-1; pfam00472
866344000485	MoCF_BD: molybdenum cofactor (MoCF) binding domain (BD). This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor, like MoaB, MogA, and MoeA. The domain is presumed to bind molybdopterin; Region: MoCF_BD; cl00451
866344000486	MoeA N-terminal region (domain I and II); Region: MoeA_N; pfam03453
866344000487	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
866344000488	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
866344000489	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
866344000490	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
866344000491	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
866344000492	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
866344000493	intersubunit interface [polypeptide binding]; other site
866344000494	active site
866344000495	zinc binding site [ion binding]; other site
866344000496	Na+ binding site [ion binding]; other site
866344000497	elongation factor P; Validated; Region: PRK00529
866344000498	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
866344000499	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
866344000500	RNA binding site [nucleotide binding]; other site
866344000501	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
866344000502	RNA binding site [nucleotide binding]; other site
866344000503	pseudaminic acid synthase; Region: PseI; TIGR03586
866344000504	NeuB family; Region: NeuB; pfam03102
866344000505	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
866344000506	NeuB binding interface [polypeptide binding]; other site
866344000507	putative substrate binding site [chemical binding]; other site
866344000508	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
866344000509	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
866344000510	Walker A/P-loop; other site
866344000511	ATP binding site [chemical binding]; other site
866344000512	Q-loop/lid; other site
866344000513	ABC transporter signature motif; other site
866344000514	Walker B; other site
866344000515	D-loop; other site
866344000516	H-loop/switch region; other site
866344000517	apolipoprotein N-acyltransferase; Reviewed; Region: PRK12291
866344000518	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
866344000519	active site
866344000520	catalytic triad [active]
866344000521	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
866344000522	Colicin V production protein; Region: Colicin_V; pfam02674
866344000523	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
866344000524	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
866344000525	dimer interface [polypeptide binding]; other site
866344000526	putative anticodon binding site; other site
866344000527	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
866344000528	motif 1; other site
866344000529	active site
866344000530	motif 2; other site
866344000531	motif 3; other site
866344000532	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
866344000533	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
866344000534	dimer interface [polypeptide binding]; other site
866344000535	active site
866344000536	glycine-pyridoxal phosphate binding site [chemical binding]; other site
866344000537	folate binding site [chemical binding]; other site
866344000538	Domain of unknown function (DUF1882); Region: DUF1882; pfam08966
866344000539	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
866344000540	Protein of unknown function DUF262; Region: DUF262; pfam03235
866344000541	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866344000542	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866344000543	Uncharacterized protein family, UPF0114; Region: UPF0114; cl01078
866344000544	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
866344000545	PLD-like domain; Region: PLDc_2; pfam13091
866344000546	putative active site [active]
866344000547	catalytic site [active]
866344000548	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
866344000549	PLD-like domain; Region: PLDc_2; pfam13091
866344000550	putative active site [active]
866344000551	catalytic site [active]
866344000552	fumarate reductase iron-sulfur subunit; Provisional; Region: frdB; PRK13552
866344000553	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
866344000554	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866344000555	fumarate reductase flavoprotein subunit; Provisional; Region: PRK08626
866344000556	L-aspartate oxidase; Provisional; Region: PRK06175
866344000557	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
866344000558	fumarate reductase cytochrome b-556 subunit; Provisional; Region: PRK13553
866344000559	Quinol:fumarate reductase (QFR) Type B subfamily, transmembrane subunit;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinone...; Region: QFR_TypeB_TM; cd00581
866344000560	Iron-sulfur protein interface; other site
866344000561	proximal heme binding site [chemical binding]; other site
866344000562	distal heme binding site [chemical binding]; other site
866344000563	dimer interface [polypeptide binding]; other site
866344000564	triosephosphate isomerase; Provisional; Region: PRK14567
866344000565	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
866344000566	substrate binding site [chemical binding]; other site
866344000567	dimer interface [polypeptide binding]; other site
866344000568	catalytic triad [active]
866344000569	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08415
866344000570	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
866344000571	NAD binding site [chemical binding]; other site
866344000572	homotetramer interface [polypeptide binding]; other site
866344000573	homodimer interface [polypeptide binding]; other site
866344000574	substrate binding site [chemical binding]; other site
866344000575	active site
866344000576	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
866344000577	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
866344000578	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
866344000579	trimer interface [polypeptide binding]; other site
866344000580	active site
866344000581	UDP-GlcNAc binding site [chemical binding]; other site
866344000582	lipid binding site [chemical binding]; lipid-binding site
866344000583	S-adenosylmethionine synthetase; Validated; Region: PRK05250
866344000584	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
866344000585	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
866344000586	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
866344000587	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
866344000588	active site
866344000589	multimer interface [polypeptide binding]; other site
866344000590	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
866344000591	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
866344000592	fatty acid/phospholipid synthesis protein PlsX; Region: plsX; TIGR00182
866344000593	3-oxoacyl-(acyl-carrier-protein) synthase III; Region: fabH; TIGR00747
866344000594	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
866344000595	dimer interface [polypeptide binding]; other site
866344000596	active site
866344000597	CoA binding pocket [chemical binding]; other site
866344000598	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
866344000599	Walker B; other site
866344000600	D-loop; other site
866344000601	H-loop/switch region; other site
866344000602	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866344000603	Walker A/P-loop; other site
866344000604	ATP binding site [chemical binding]; other site
866344000605	antiporter inner membrane protein; Provisional; Region: PRK11670
866344000606	Domain of unknown function DUF59; Region: DUF59; pfam01883
866344000607	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
866344000608	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
866344000609	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
866344000610	Ligand binding site; other site
866344000611	metal-binding site
866344000612	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866344000613	heat shock protein 90; Provisional; Region: PRK05218
866344000614	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866344000615	ATP binding site [chemical binding]; other site
866344000616	Mg2+ binding site [ion binding]; other site
866344000617	G-X-G motif; other site
866344000618	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866344000619	Sel1-like repeats; Region: SEL1; smart00671
866344000620	Sel1-like repeats; Region: SEL1; smart00671
866344000621	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866344000622	TPR motif; other site
866344000623	binding surface
866344000624	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
866344000625	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
866344000626	metal binding site [ion binding]; metal-binding site
866344000627	dimer interface [polypeptide binding]; other site
866344000628	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
866344000629	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866344000630	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
866344000631	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
866344000632	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
866344000633	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
866344000634	transmembrane helices; other site
866344000635	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
866344000636	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
866344000637	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: Dxr; TIGR00243
866344000638	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
866344000639	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
866344000640	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
866344000641	Beta-1,4-N-acetylgalactosaminyltransferase (CgtA); Region: CgtA; pfam06306
866344000642	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
866344000643	substrate binding site [chemical binding]; other site
866344000644	Helix-turn-helix domain; Region: HTH_28; pfam13518
866344000645	cysteine desulfurase, NifS family, epsilon proteobacteria type; Region: nifS_epsilon; TIGR03403
866344000646	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
866344000647	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866344000648	catalytic residue [active]
866344000649	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
866344000650	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
866344000651	trimerization site [polypeptide binding]; other site
866344000652	active site
866344000653	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
866344000654	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
866344000655	DNA repair protein RadA; Region: sms; TIGR00416
866344000656	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
866344000657	Walker A motif/ATP binding site; other site
866344000658	ATP binding site [chemical binding]; other site
866344000659	Walker B motif; other site
866344000660	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
866344000661	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
866344000662	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
866344000663	SelR domain; Region: SelR; pfam01641
866344000664	Predicted permeases [General function prediction only]; Region: COG0730
866344000665	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344000666	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
866344000667	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
866344000668	Sulfate transporter family; Region: Sulfate_transp; pfam00916
866344000669	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344000670	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
866344000671	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
866344000672	Ligand binding site; other site
866344000673	oligomer interface; other site
866344000674	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
866344000675	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
866344000676	hypothetical protein; Provisional; Region: PRK04081
866344000677	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
866344000678	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3295
866344000679	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866344000680	Sel1-like repeats; Region: SEL1; smart00671
866344000681	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866344000682	TPR motif; other site
866344000683	binding surface
866344000684	Sel1-like repeats; Region: SEL1; smart00671
866344000685	Sel1-like repeats; Region: SEL1; smart00671
866344000686	Sel1-like repeats; Region: SEL1; smart00671
866344000687	Cytochrome c; Region: Cytochrom_C; cl11414
866344000688	Porphobilinogen deaminase [Coenzyme metabolism]; Region: HemC; COG0181
866344000689	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
866344000690	domain interfaces; other site
866344000691	active site
866344000692	prolyl-tRNA synthetase, family II; Region: proS_fam_II; TIGR00409
866344000693	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
866344000694	dimer interface [polypeptide binding]; other site
866344000695	motif 1; other site
866344000696	active site
866344000697	motif 2; other site
866344000698	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
866344000699	putative deacylase active site [active]
866344000700	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
866344000701	active site
866344000702	motif 3; other site
866344000703	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
866344000704	anticodon binding site; other site
866344000705	glutamyl-tRNA reductase; Region: hemA; TIGR01035
866344000706	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
866344000707	tRNA; other site
866344000708	putative tRNA binding site [nucleotide binding]; other site
866344000709	putative NADP binding site [chemical binding]; other site
866344000710	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
866344000711	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
866344000712	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
866344000713	substrate binding pocket [chemical binding]; other site
866344000714	chain length determination region; other site
866344000715	substrate-Mg2+ binding site; other site
866344000716	catalytic residues [active]
866344000717	aspartate-rich region 1; other site
866344000718	active site lid residues [active]
866344000719	aspartate-rich region 2; other site
866344000720	Domain of unknown function (DUF2018); Region: DUF2018; pfam09442
866344000721	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
866344000722	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
866344000723	dimerization interface [polypeptide binding]; other site
866344000724	DPS ferroxidase diiron center [ion binding]; other site
866344000725	ion pore; other site
866344000726	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
866344000727	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866344000728	dimer interface [polypeptide binding]; other site
866344000729	phosphorylation site [posttranslational modification]
866344000730	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866344000731	ATP binding site [chemical binding]; other site
866344000732	Mg2+ binding site [ion binding]; other site
866344000733	G-X-G motif; other site
866344000734	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
866344000735	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
866344000736	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
866344000737	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
866344000738	ATP binding site [chemical binding]; other site
866344000739	Mg++ binding site [ion binding]; other site
866344000740	motif III; other site
866344000741	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866344000742	nucleotide binding region [chemical binding]; other site
866344000743	ATP-binding site [chemical binding]; other site
866344000744	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
866344000745	SPFH domain / Band 7 family; Region: Band_7; pfam01145
866344000746	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
866344000747	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
866344000748	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866344000749	Walker A/P-loop; other site
866344000750	ATP binding site [chemical binding]; other site
866344000751	Q-loop/lid; other site
866344000752	ABC transporter signature motif; other site
866344000753	Walker B; other site
866344000754	D-loop; other site
866344000755	H-loop/switch region; other site
866344000756	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
866344000757	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866344000758	Walker A/P-loop; other site
866344000759	ATP binding site [chemical binding]; other site
866344000760	Q-loop/lid; other site
866344000761	ABC transporter signature motif; other site
866344000762	Walker B; other site
866344000763	D-loop; other site
866344000764	H-loop/switch region; other site
866344000765	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
866344000766	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
866344000767	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866344000768	dimer interface [polypeptide binding]; other site
866344000769	conserved gate region; other site
866344000770	putative PBP binding loops; other site
866344000771	ABC-ATPase subunit interface; other site
866344000772	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344000773	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344000774	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
866344000775	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
866344000776	GDP-binding site [chemical binding]; other site
866344000777	ACT binding site; other site
866344000778	IMP binding site; other site
866344000779	Flagellar FliJ protein; Region: FliJ; pfam02050
866344000780	Uncharacterized conserved protein [Function unknown]; Region: COG3334
866344000781	RIP metalloprotease RseP; Region: TIGR00054
866344000782	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
866344000783	active site
866344000784	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
866344000785	protein binding site [polypeptide binding]; other site
866344000786	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
866344000787	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
866344000788	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
866344000789	generic binding surface II; other site
866344000790	generic binding surface I; other site
866344000791	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
866344000792	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344000793	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344000794	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866344000795	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344000796	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
866344000797	Clp amino terminal domain; Region: Clp_N; pfam02861
866344000798	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344000799	Walker A motif; other site
866344000800	ATP binding site [chemical binding]; other site
866344000801	Walker B motif; other site
866344000802	arginine finger; other site
866344000803	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344000804	Walker A motif; other site
866344000805	ATP binding site [chemical binding]; other site
866344000806	Walker B motif; other site
866344000807	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
866344000808	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
866344000809	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
866344000810	Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; Region: PyrC; COG0044
866344000811	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
866344000812	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
866344000813	active site
866344000814	chlorohydrolase; Provisional; Region: PRK08418
866344000815	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_D; cd01312
866344000816	active site
866344000817	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
866344000818	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14339
866344000819	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866344000820	FeS/SAM binding site; other site
866344000821	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
866344000822	putative acyl-acceptor binding pocket; other site
866344000823	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
866344000824	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
866344000825	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
866344000826	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
866344000827	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
866344000828	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
866344000829	putative active site [active]
866344000830	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
866344000831	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
866344000832	putative acyl-acceptor binding pocket; other site
866344000833	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
866344000834	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
866344000835	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3400
866344000836	TrkA-C domain; Region: TrkA_C; pfam02080
866344000837	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
866344000838	active site
866344000839	dimer interface [polypeptide binding]; other site
866344000840	metal binding site [ion binding]; metal-binding site
866344000841	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
866344000842	Mechanosensitive ion channel; Region: MS_channel; pfam00924
866344000843	radical SAM methylthiotransferase, MiaB/RimO family; Region: TIGR00089
866344000844	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
866344000845	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866344000846	FeS/SAM binding site; other site
866344000847	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
866344000848	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344000849	Walker A motif; other site
866344000850	ATP binding site [chemical binding]; other site
866344000851	Walker B motif; other site
866344000852	arginine finger; other site
866344000853	Domain of unknown function (DUF4149); Region: DUF4149; pfam13664
866344000854	Vacuolating cyotoxin; Region: VacA; pfam02691
866344000855	Autotransporter beta-domain; Region: Autotransporter; cl17461
866344000856	diaminopimelate decarboxylase; Region: lysA; TIGR01048
866344000857	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
866344000858	active site
866344000859	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866344000860	substrate binding site [chemical binding]; other site
866344000861	catalytic residues [active]
866344000862	dimer interface [polypeptide binding]; other site
866344000863	Chorismate mutase [Amino acid transport and metabolism]; Region: PheA; COG1605
866344000864	Uncharacterized conserved protein [Function unknown]; Region: COG4866
866344000865	aminodeoxychorismate synthase; Provisional; Region: PRK07508
866344000866	chorismate binding enzyme; Region: Chorismate_bind; cl10555
866344000867	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
866344000868	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
866344000869	substrate-cofactor binding pocket; other site
866344000870	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866344000871	catalytic residue [active]
866344000872	acylamide amidohydrolase; Provisional; Region: amiE; PRK13286
866344000873	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
866344000874	multimer interface [polypeptide binding]; other site
866344000875	active site
866344000876	catalytic triad [active]
866344000877	dimer interface [polypeptide binding]; other site
866344000878	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK08412
866344000879	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
866344000880	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
866344000881	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
866344000882	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
866344000883	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
866344000884	peptide binding site [polypeptide binding]; other site
866344000885	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
866344000886	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866344000887	dimer interface [polypeptide binding]; other site
866344000888	conserved gate region; other site
866344000889	putative PBP binding loops; other site
866344000890	ABC-ATPase subunit interface; other site
866344000891	dipeptide transporter; Provisional; Region: PRK10913
866344000892	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
866344000893	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866344000894	dimer interface [polypeptide binding]; other site
866344000895	conserved gate region; other site
866344000896	putative PBP binding loops; other site
866344000897	ABC-ATPase subunit interface; other site
866344000898	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866344000899	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
866344000900	Walker A/P-loop; other site
866344000901	ATP binding site [chemical binding]; other site
866344000902	Q-loop/lid; other site
866344000903	ABC transporter signature motif; other site
866344000904	Walker B; other site
866344000905	D-loop; other site
866344000906	H-loop/switch region; other site
866344000907	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
866344000908	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
866344000909	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866344000910	Walker A/P-loop; other site
866344000911	ATP binding site [chemical binding]; other site
866344000912	Q-loop/lid; other site
866344000913	ABC transporter signature motif; other site
866344000914	Walker B; other site
866344000915	D-loop; other site
866344000916	H-loop/switch region; other site
866344000917	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
866344000918	GTPase CgtA; Reviewed; Region: obgE; PRK12299
866344000919	GTP1/OBG; Region: GTP1_OBG; pfam01018
866344000920	Obg GTPase; Region: Obg; cd01898
866344000921	G1 box; other site
866344000922	GTP/Mg2+ binding site [chemical binding]; other site
866344000923	Switch I region; other site
866344000924	G2 box; other site
866344000925	G3 box; other site
866344000926	Switch II region; other site
866344000927	G4 box; other site
866344000928	G5 box; other site
866344000929	Alginate lyase; Region: Alginate_lyase; pfam05426
866344000930	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
866344000931	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
866344000932	inhibitor-cofactor binding pocket; inhibition site
866344000933	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866344000934	catalytic residue [active]
866344000935	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
866344000936	Predicted amidohydrolase [General function prediction only]; Region: COG0388
866344000937	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
866344000938	active site
866344000939	catalytic triad [active]
866344000940	dimer interface [polypeptide binding]; other site
866344000941	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
866344000942	active site
866344000943	catalytic site [active]
866344000944	Zn binding site [ion binding]; other site
866344000945	tetramer interface [polypeptide binding]; other site
866344000946	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
866344000947	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866344000948	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344000949	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
866344000950	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
866344000951	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
866344000952	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866344000953	putative substrate translocation pore; other site
866344000954	Major Facilitator Superfamily; Region: MFS_1; pfam07690
866344000955	heme oxygenase, HugZ family; Region: heme_ox_HugZ; TIGR04109
866344000956	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
866344000957	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
866344000958	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
866344000959	arginyl-tRNA synthetase; Region: argS; TIGR00456
866344000960	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
866344000961	active site
866344000962	HIGH motif; other site
866344000963	KMSK motif region; other site
866344000964	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
866344000965	tRNA binding surface [nucleotide binding]; other site
866344000966	anticodon binding site; other site
866344000967	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
866344000968	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
866344000969	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
866344000970	catalytic site [active]
866344000971	G-X2-G-X-G-K; other site
866344000972	nuclease NucT; Provisional; Region: PRK13912
866344000973	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
866344000974	putative active site [active]
866344000975	catalytic site [active]
866344000976	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344000977	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
866344000978	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
866344000979	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
866344000980	ligand binding site; other site
866344000981	tetramer interface; other site
866344000982	Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: spsG; COG3980
866344000983	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
866344000984	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
866344000985	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
866344000986	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
866344000987	NAD synthetase; Provisional; Region: PRK13980
866344000988	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
866344000989	homodimer interface [polypeptide binding]; other site
866344000990	NAD binding pocket [chemical binding]; other site
866344000991	ATP binding pocket [chemical binding]; other site
866344000992	Mg binding site [ion binding]; other site
866344000993	active-site loop [active]
866344000994	ketol-acid reductoisomerase; Provisional; Region: PRK05479
866344000995	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
866344000996	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
866344000997	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
866344000998	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
866344000999	Switch I; other site
866344001000	Switch II; other site
866344001001	cell division topological specificity factor MinE; Region: minE; TIGR01215
866344001002	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
866344001003	DNA protecting protein DprA; Region: dprA; TIGR00732
866344001004	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
866344001005	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866344001006	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
866344001007	Sel1-like repeats; Region: SEL1; smart00671
866344001008	Sel1-like repeats; Region: SEL1; smart00671
866344001009	chlorohydrolase; Provisional; Region: PRK07213
866344001010	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
866344001011	catalytic residue [active]
866344001012	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
866344001013	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
866344001014	active site
866344001015	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
866344001016	DHH family; Region: DHH; pfam01368
866344001017	DHHA1 domain; Region: DHHA1; pfam02272
866344001018	CTP synthetase; Validated; Region: pyrG; PRK05380
866344001019	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
866344001020	Catalytic site [active]
866344001021	active site
866344001022	UTP binding site [chemical binding]; other site
866344001023	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
866344001024	active site
866344001025	putative oxyanion hole; other site
866344001026	catalytic triad [active]
866344001027	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
866344001028	active site
866344001029	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
866344001030	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
866344001031	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
866344001032	flagellar motor switch protein FliG; Region: fliG; TIGR00207
866344001033	FliG C-terminal domain; Region: FliG_C; pfam01706
866344001034	flagellar assembly protein H; Validated; Region: fliH; PRK06669
866344001035	Flagellar assembly protein FliH; Region: FliH; pfam02108
866344001036	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
866344001037	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
866344001038	TPP-binding site; other site
866344001039	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
866344001040	PYR/PP interface [polypeptide binding]; other site
866344001041	dimer interface [polypeptide binding]; other site
866344001042	TPP binding site [chemical binding]; other site
866344001043	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
866344001044	GTP-binding protein LepA; Provisional; Region: PRK05433
866344001045	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
866344001046	G1 box; other site
866344001047	putative GEF interaction site [polypeptide binding]; other site
866344001048	GTP/Mg2+ binding site [chemical binding]; other site
866344001049	Switch I region; other site
866344001050	G2 box; other site
866344001051	G3 box; other site
866344001052	Switch II region; other site
866344001053	G4 box; other site
866344001054	G5 box; other site
866344001055	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
866344001056	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
866344001057	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
866344001058	Domain of unknown function (DUF3883); Region: DUF3883; pfam13020
866344001059	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
866344001060	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
866344001061	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
866344001062	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866344001063	putative substrate translocation pore; other site
866344001064	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
866344001065	TspO/MBR family; Region: TspO_MBR; cl01379
866344001066	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
866344001067	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
866344001068	Inactivated superfamily I helicase [DNA replication, recombination, and repair]; Region: COG3893
866344001069	RecB family exonuclease [DNA replication, recombination, and repair]; Region: COG2887
866344001070	transketolase, bacterial and yeast; Region: tktlase_bact; TIGR00232
866344001071	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
866344001072	TPP-binding site [chemical binding]; other site
866344001073	dimer interface [polypeptide binding]; other site
866344001074	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
866344001075	PYR/PP interface [polypeptide binding]; other site
866344001076	dimer interface [polypeptide binding]; other site
866344001077	TPP binding site [chemical binding]; other site
866344001078	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
866344001079	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
866344001080	riboflavin kinase/FMN adenylyltransferase; Region: ribF; TIGR00083
866344001081	active site
866344001082	Riboflavin kinase; Region: Flavokinase; smart00904
866344001083	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866344001084	hemolysin TlyA family protein; Region: tly; TIGR00478
866344001085	RNA binding surface [nucleotide binding]; other site
866344001086	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
866344001087	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
866344001088	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
866344001089	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
866344001090	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866344001091	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
866344001092	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
866344001093	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866344001094	Walker A/P-loop; other site
866344001095	ATP binding site [chemical binding]; other site
866344001096	Q-loop/lid; other site
866344001097	ABC transporter signature motif; other site
866344001098	Walker B; other site
866344001099	D-loop; other site
866344001100	H-loop/switch region; other site
866344001101	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
866344001102	Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes [Defense mechanisms]; Region: COG1787
866344001103	Restriction endonuclease; Region: Mrr_cat; pfam04471
866344001104	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
866344001105	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cd00596
866344001106	active site
866344001107	Zn binding site [ion binding]; other site
866344001108	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
866344001109	metal-binding site [ion binding]
866344001110	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
866344001111	metal-binding site [ion binding]
866344001112	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
866344001113	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
866344001114	Soluble P-type ATPase [General function prediction only]; Region: COG4087
866344001115	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
866344001116	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
866344001117	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
866344001118	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344001119	Walker A motif; other site
866344001120	ATP binding site [chemical binding]; other site
866344001121	Walker B motif; other site
866344001122	arginine finger; other site
866344001123	Peptidase family M41; Region: Peptidase_M41; pfam01434
866344001124	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
866344001125	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866344001126	S-adenosylmethionine binding site [chemical binding]; other site
866344001127	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
866344001128	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866344001129	active site
866344001130	phosphorylation site [posttranslational modification]
866344001131	intermolecular recognition site; other site
866344001132	dimerization interface [polypeptide binding]; other site
866344001133	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344001134	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
866344001135	16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Region: gidB; TIGR00138
866344001136	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
866344001137	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
866344001138	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
866344001139	sec-independent translocase; Provisional; Region: PRK04098
866344001140	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
866344001141	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344001142	Walker A motif; other site
866344001143	ATP binding site [chemical binding]; other site
866344001144	Walker B motif; other site
866344001145	arginine finger; other site
866344001146	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
866344001147	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
866344001148	oligomerization interface [polypeptide binding]; other site
866344001149	active site
866344001150	metal binding site [ion binding]; metal-binding site
866344001151	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344001152	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344001153	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
866344001154	septum formation inhibitor; Reviewed; Region: minC; PRK00556
866344001155	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
866344001156	UDP-3-0-acyl N-acetylglucosamine deacetylase; Region: lpxC; TIGR00325
866344001157	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
866344001158	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
866344001159	homoserine kinase; Region: thrB; TIGR00191
866344001160	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
866344001161	Predicted nucleic-acid-binding protein implicated in transcription termination [Transcription]; Region: COG2740
866344001162	putative RNA binding cleft [nucleotide binding]; other site
866344001163	translation initiation factor IF-2; Region: IF-2; TIGR00487
866344001164	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
866344001165	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
866344001166	G1 box; other site
866344001167	putative GEF interaction site [polypeptide binding]; other site
866344001168	GTP/Mg2+ binding site [chemical binding]; other site
866344001169	Switch I region; other site
866344001170	G2 box; other site
866344001171	G3 box; other site
866344001172	Switch II region; other site
866344001173	G4 box; other site
866344001174	G5 box; other site
866344001175	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
866344001176	Translation-initiation factor 2; Region: IF-2; pfam11987
866344001177	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
866344001178	Ribosome-binding factor A; Region: RBFA; cl00542
866344001179	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
866344001180	Sm and related proteins; Region: Sm_like; cl00259
866344001181	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
866344001182	putative oligomer interface [polypeptide binding]; other site
866344001183	putative RNA binding site [nucleotide binding]; other site
866344001184	acetyl-CoA synthetase; Provisional; Region: PRK00174
866344001185	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
866344001186	active site
866344001187	CoA binding site [chemical binding]; other site
866344001188	acyl-activating enzyme (AAE) consensus motif; other site
866344001189	AMP binding site [chemical binding]; other site
866344001190	acetate binding site [chemical binding]; other site
866344001191	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
866344001192	putative active site [active]
866344001193	putative metal binding site [ion binding]; other site
866344001194	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
866344001195	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
866344001196	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866344001197	active site
866344001198	intermolecular recognition site; other site
866344001199	dimerization interface [polypeptide binding]; other site
866344001200	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866344001201	DNA binding site [nucleotide binding]
866344001202	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
866344001203	DHH family; Region: DHH; pfam01368
866344001204	flagellar biosynthesis protein FlhA; Region: FlhA; TIGR01398
866344001205	FHIPEP family; Region: FHIPEP; pfam00771
866344001206	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
866344001207	16S/18S rRNA binding site [nucleotide binding]; other site
866344001208	S13e-L30e interaction site [polypeptide binding]; other site
866344001209	25S rRNA binding site [nucleotide binding]; other site
866344001210	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
866344001211	O-Antigen ligase; Region: Wzy_C; pfam04932
866344001212	Dehydroquinase class II; Region: DHquinase_II; pfam01220
866344001213	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
866344001214	trimer interface [polypeptide binding]; other site
866344001215	active site
866344001216	dimer interface [polypeptide binding]; other site
866344001217	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
866344001218	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
866344001219	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
866344001220	active site
866344001221	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
866344001222	catalytic center binding site [active]
866344001223	ATP binding site [chemical binding]; other site
866344001224	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
866344001225	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
866344001226	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
866344001227	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
866344001228	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
866344001229	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
866344001230	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
866344001231	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
866344001232	DNA binding residues [nucleotide binding]
866344001233	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
866344001234	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
866344001235	flagellar motor switch protein FliY; Validated; Region: PRK08432
866344001236	flagellar motor switch protein FliN; Region: fliN; TIGR02480
866344001237	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
866344001238	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4731
866344001239	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
866344001240	metal binding site 2 [ion binding]; metal-binding site
866344001241	putative DNA binding helix; other site
866344001242	metal binding site 1 [ion binding]; metal-binding site
866344001243	dimer interface [polypeptide binding]; other site
866344001244	structural Zn2+ binding site [ion binding]; other site
866344001245	ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; Region: MGS1; COG2256
866344001246	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344001247	Walker A motif; other site
866344001248	ATP binding site [chemical binding]; other site
866344001249	Walker B motif; other site
866344001250	arginine finger; other site
866344001251	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
866344001252	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
866344001253	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
866344001254	DNA binding residues [nucleotide binding]
866344001255	putative dimer interface [polypeptide binding]; other site
866344001256	chaperone protein DnaJ; Provisional; Region: PRK14299
866344001257	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
866344001258	HSP70 interaction site [polypeptide binding]; other site
866344001259	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
866344001260	substrate binding site [polypeptide binding]; other site
866344001261	dimer interface [polypeptide binding]; other site
866344001262	5'-3' exonuclease; Provisional; Region: PRK14976
866344001263	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
866344001264	putative active site [active]
866344001265	Helix-hairpin-helix class 2 (Pol1 family) motifs; Region: HhH2; smart00279
866344001266	DNA binding site [nucleotide binding]
866344001267	metal binding site [ion binding]; metal-binding site
866344001268	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
866344001269	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866344001270	active site
866344001271	intermolecular recognition site; other site
866344001272	dimerization interface [polypeptide binding]; other site
866344001273	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
866344001274	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
866344001275	substrate binding site; other site
866344001276	dimer interface; other site
866344001277	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
866344001278	homotrimer interaction site [polypeptide binding]; other site
866344001279	zinc binding site [ion binding]; other site
866344001280	CDP-binding sites; other site
866344001281	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
866344001282	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
866344001283	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
866344001284	protein binding site [polypeptide binding]; other site
866344001285	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
866344001286	protein binding site [polypeptide binding]; other site
866344001287	S-methylmethionine transporter; Provisional; Region: PRK11387
866344001288	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Region: pgsA; TIGR00560
866344001289	7-alpha-hydroxysteroid dehydrogenase; Provisional; Region: PRK08416
866344001290	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
866344001291	putative NAD(P) binding site [chemical binding]; other site
866344001292	active site
866344001293	dihydrodipicolinate synthase; Region: dapA; TIGR00674
866344001294	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
866344001295	dimer interface [polypeptide binding]; other site
866344001296	active site
866344001297	catalytic residue [active]
866344001298	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
866344001299	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
866344001300	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
866344001301	dihydroorotate dehydrogenase, subfamily 2; Region: pyrD_sub2; TIGR01036
866344001302	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
866344001303	quinone interaction residues [chemical binding]; other site
866344001304	active site
866344001305	catalytic residues [active]
866344001306	FMN binding site [chemical binding]; other site
866344001307	substrate binding site [chemical binding]; other site
866344001308	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
866344001309	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
866344001310	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
866344001311	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
866344001312	putative domain interface [polypeptide binding]; other site
866344001313	putative active site [active]
866344001314	catalytic site [active]
866344001315	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
866344001316	putative active site [active]
866344001317	putative domain interface [polypeptide binding]; other site
866344001318	catalytic site [active]
866344001319	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866344001320	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
866344001321	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
866344001322	Methyltransferase domain; Region: Methyltransf_26; pfam13659
866344001323	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
866344001324	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
866344001325	ATP binding site [chemical binding]; other site
866344001326	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
866344001327	putative Mg++ binding site [ion binding]; other site
866344001328	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
866344001329	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
866344001330	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
866344001331	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
866344001332	putative metal binding site [ion binding]; other site
866344001333	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
866344001334	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
866344001335	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
866344001336	active site
866344001337	Zn binding site [ion binding]; other site
866344001338	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
866344001339	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
866344001340	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344001341	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
866344001342	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
866344001343	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
866344001344	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866344001345	dimer interface [polypeptide binding]; other site
866344001346	conserved gate region; other site
866344001347	putative PBP binding loops; other site
866344001348	ABC-ATPase subunit interface; other site
866344001349	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866344001350	Walker A/P-loop; other site
866344001351	ATP binding site [chemical binding]; other site
866344001352	Q-loop/lid; other site
866344001353	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866344001354	Walker B; other site
866344001355	D-loop; other site
866344001356	H-loop/switch region; other site
866344001357	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
866344001358	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
866344001359	active site
866344001360	HIGH motif; other site
866344001361	nucleotide binding site [chemical binding]; other site
866344001362	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
866344001363	active site
866344001364	KMSKS motif; other site
866344001365	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344001366	Helix-turn-helix domain; Region: HTH_17; pfam12728
866344001367	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
866344001368	Methyltransferase domain; Region: Methyltransf_26; pfam13659
866344001369	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
866344001370	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
866344001371	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
866344001372	ADP-heptose:LPS heptosyl transferase I; Provisional; Region: PRK10964; cl15782
866344001373	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
866344001374	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
866344001375	G1 box; other site
866344001376	putative GEF interaction site [polypeptide binding]; other site
866344001377	GTP/Mg2+ binding site [chemical binding]; other site
866344001378	Switch I region; other site
866344001379	G2 box; other site
866344001380	G3 box; other site
866344001381	Switch II region; other site
866344001382	G4 box; other site
866344001383	G5 box; other site
866344001384	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
866344001385	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
866344001386	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
866344001387	Probable transposase; Region: OrfB_IS605; pfam01385
866344001388	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
866344001389	Uncharacterized conserved protein (DUF2349); Region: DUF2349; pfam09779
866344001390	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
866344001391	DNA primase, catalytic core; Region: dnaG; TIGR01391
866344001392	CHC2 zinc finger; Region: zf-CHC2; pfam01807
866344001393	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
866344001394	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
866344001395	active site
866344001396	metal binding site [ion binding]; metal-binding site
866344001397	interdomain interaction site; other site
866344001398	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
866344001399	Walker A motif; other site
866344001400	ATP binding site [chemical binding]; other site
866344001401	Walker B motif; other site
866344001402	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
866344001403	putative DNA binding site [nucleotide binding]; other site
866344001404	putative Zn2+ binding site [ion binding]; other site
866344001405	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
866344001406	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
866344001407	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
866344001408	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
866344001409	Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153
866344001410	putative heme binding pocket [chemical binding]; other site
866344001411	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866344001412	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866344001413	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
866344001414	Uncharacterized conserved protein [Function unknown]; Region: COG1432
866344001415	LabA_like proteins; Region: LabA_like; cd06167
866344001416	putative metal binding site [ion binding]; other site
866344001417	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
866344001418	active site
866344001419	putative DNA-binding cleft [nucleotide binding]; other site
866344001420	dimer interface [polypeptide binding]; other site
866344001421	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
866344001422	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866344001423	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866344001424	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
866344001425	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
866344001426	tetramer interface [polypeptide binding]; other site
866344001427	heme binding pocket [chemical binding]; other site
866344001428	NADPH binding site [chemical binding]; other site
866344001429	alkylphosphonate utilization operon protein PhnA; Region: phnA; TIGR00686
866344001430	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
866344001431	PhnA protein; Region: PhnA; pfam03831
866344001432	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
866344001433	flagellar hook protein FlgE; Validated; Region: flgE; PRK08425
866344001434	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
866344001435	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
866344001436	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
866344001437	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
866344001438	hydrogenase nickel incorporation protein; Provisional; Region: hypA; PRK00564
866344001439	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
866344001440	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
866344001441	lipid-A-disaccharide synthase; Region: lpxB; TIGR00215
866344001442	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
866344001443	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
866344001444	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
866344001445	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
866344001446	trimer interface [polypeptide binding]; other site
866344001447	active site
866344001448	PQQ-like domain; Region: PQQ_2; pfam13360
866344001449	pantothenate kinase; Reviewed; Region: PRK13333
866344001450	Uncharacterized conserved protein [Function unknown]; Region: COG2836
866344001451	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
866344001452	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
866344001453	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866344001454	active site
866344001455	motif I; other site
866344001456	motif II; other site
866344001457	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
866344001458	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
866344001459	NAD(P) binding site [chemical binding]; other site
866344001460	active site
866344001461	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
866344001462	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
866344001463	putative ribose interaction site [chemical binding]; other site
866344001464	putative ADP binding site [chemical binding]; other site
866344001465	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
866344001466	active site
866344001467	nucleotide binding site [chemical binding]; other site
866344001468	HIGH motif; other site
866344001469	KMSKS motif; other site
866344001470	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
866344001471	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
866344001472	dimer interface [polypeptide binding]; other site
866344001473	active site
866344001474	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
866344001475	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
866344001476	active site
866344001477	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
866344001478	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866344001479	Walker A/P-loop; other site
866344001480	ATP binding site [chemical binding]; other site
866344001481	Q-loop/lid; other site
866344001482	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
866344001483	ABC transporter; Region: ABC_tran_2; pfam12848
866344001484	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
866344001485	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2958
866344001486	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
866344001487	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
866344001488	active site
866344001489	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
866344001490	HsdM N-terminal domain; Region: HsdM_N; pfam12161
866344001491	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866344001492	S-adenosylmethionine binding site [chemical binding]; other site
866344001493	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866344001494	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
866344001495	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866344001496	potential frameshift: common BLAST hit: gi|188527307|ref|YP_001909994.1| type I restriction enzyme R protein
866344001497	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
866344001498	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
866344001499	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
866344001500	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866344001501	ATP binding site [chemical binding]; other site
866344001502	putative Mg++ binding site [ion binding]; other site
866344001503	Type I restriction and modification enzyme - subunit R C terminal; Region: EcoR124_C; pfam12008
866344001504	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
866344001505	substrate binding site [chemical binding]; other site
866344001506	multimerization interface [polypeptide binding]; other site
866344001507	ATP binding site [chemical binding]; other site
866344001508	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
866344001509	dimer interface [polypeptide binding]; other site
866344001510	substrate binding site [chemical binding]; other site
866344001511	ATP binding site [chemical binding]; other site
866344001512	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
866344001513	thiamine phosphate binding site [chemical binding]; other site
866344001514	active site
866344001515	pyrophosphate binding site [ion binding]; other site
866344001516	phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Region: coaBC_dfp; TIGR00521
866344001517	Flavoprotein; Region: Flavoprotein; pfam02441
866344001518	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
866344001519	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
866344001520	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
866344001521	NAD(P) binding site [chemical binding]; other site
866344001522	homodimer interface [polypeptide binding]; other site
866344001523	substrate binding site [chemical binding]; other site
866344001524	active site
866344001525	Long-chain fatty acid transport protein [Lipid metabolism]; Region: FadL; COG2067
866344001526	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
866344001527	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
866344001528	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
866344001529	IHF dimer interface [polypeptide binding]; other site
866344001530	IHF - DNA interface [nucleotide binding]; other site
866344001531	GTP-binding protein Der; Reviewed; Region: PRK00093
866344001532	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
866344001533	G1 box; other site
866344001534	GTP/Mg2+ binding site [chemical binding]; other site
866344001535	Switch I region; other site
866344001536	G2 box; other site
866344001537	Switch II region; other site
866344001538	G3 box; other site
866344001539	G4 box; other site
866344001540	G5 box; other site
866344001541	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
866344001542	G1 box; other site
866344001543	GTP/Mg2+ binding site [chemical binding]; other site
866344001544	Switch I region; other site
866344001545	G2 box; other site
866344001546	G3 box; other site
866344001547	Switch II region; other site
866344001548	G4 box; other site
866344001549	G5 box; other site
866344001550	spermidine synthase; Provisional; Region: speE; PRK00536
866344001551	spermidine synthase; Provisional; Region: PRK00811
866344001552	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
866344001553	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
866344001554	CoA-binding site [chemical binding]; other site
866344001555	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; Region: gatA; TIGR00132
866344001556	indole acetimide hydrolase; Validated; Region: PRK07488
866344001557	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
866344001558	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
866344001559	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
866344001560	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
866344001561	active site
866344001562	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
866344001563	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
866344001564	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
866344001565	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
866344001566	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
866344001567	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
866344001568	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
866344001569	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866344001570	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
866344001571	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
866344001572	catalytic residues [active]
866344001573	Predicted endonuclease distantly related to archaeal Holliday junction resolvase [DNA replication, recombination, and repair]; Region: COG0792
866344001574	homoserine dehydrogenase; Provisional; Region: PRK06349
866344001575	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
866344001576	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
866344001577	excinuclease ABC, C subunit; Region: uvrC; TIGR00194
866344001578	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
866344001579	GIY-YIG motif/motif A; other site
866344001580	active site
866344001581	catalytic site [active]
866344001582	putative DNA binding site [nucleotide binding]; other site
866344001583	metal binding site [ion binding]; metal-binding site
866344001584	UvrB/uvrC motif; Region: UVR; pfam02151
866344001585	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
866344001586	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
866344001587	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866344001588	Walker A/P-loop; other site
866344001589	ATP binding site [chemical binding]; other site
866344001590	Q-loop/lid; other site
866344001591	ABC transporter signature motif; other site
866344001592	Walker B; other site
866344001593	D-loop; other site
866344001594	H-loop/switch region; other site
866344001595	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866344001596	dimer interface [polypeptide binding]; other site
866344001597	conserved gate region; other site
866344001598	ABC-ATPase subunit interface; other site
866344001599	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
866344001600	flagellar motor protein MotB; Reviewed; Region: motB; PRK08457
866344001601	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
866344001602	ligand binding site [chemical binding]; other site
866344001603	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
866344001604	flagellar motor protein MotA; Validated; Region: PRK08456
866344001605	potential frameshift: common BLAST hit: gi|188527341|ref|YP_001910028.1| thiamin biosynthesis protein ThiF
866344001606	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
866344001607	ATP binding site [chemical binding]; other site
866344001608	substrate interface [chemical binding]; other site
866344001609	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cl17196
866344001610	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
866344001611	Uncharacterized conserved protein [Function unknown]; Region: COG1565
866344001612	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
866344001613	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
866344001614	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK08455
866344001615	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
866344001616	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
866344001617	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
866344001618	N-terminal plug; other site
866344001619	ligand-binding site [chemical binding]; other site
866344001620	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
866344001621	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
866344001622	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09314
866344001623	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
866344001624	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cl00522
866344001625	Domain of unknown function (DUF3943); Region: DUF3943; pfam13084
866344001626	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
866344001627	dimerization interface [polypeptide binding]; other site
866344001628	active site
866344001629	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
866344001630	MoaE interaction surface [polypeptide binding]; other site
866344001631	MoeB interaction surface [polypeptide binding]; other site
866344001632	thiocarboxylated glycine; other site
866344001633	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
866344001634	MoaE homodimer interface [polypeptide binding]; other site
866344001635	MoaD interaction [polypeptide binding]; other site
866344001636	active site residues [active]
866344001637	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
866344001638	MPT binding site; other site
866344001639	trimer interface [polypeptide binding]; other site
866344001640	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
866344001641	trimer interface [polypeptide binding]; other site
866344001642	dimer interface [polypeptide binding]; other site
866344001643	putative active site [active]
866344001644	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
866344001645	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344001646	trigger factor; Provisional; Region: tig; PRK01490
866344001647	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
866344001648	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
866344001649	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
866344001650	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
866344001651	oligomer interface [polypeptide binding]; other site
866344001652	active site residues [active]
866344001653	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
866344001654	active site
866344001655	catalytic residues [active]
866344001656	metal binding site [ion binding]; metal-binding site
866344001657	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
866344001658	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
866344001659	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
866344001660	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
866344001661	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207
866344001662	metal-binding site [ion binding]
866344001663	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
866344001664	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
866344001665	Soluble P-type ATPase [General function prediction only]; Region: COG4087
866344001666	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866344001667	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
866344001668	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866344001669	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866344001670	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
866344001671	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
866344001672	FtsX-like permease family; Region: FtsX; pfam02687
866344001673	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
866344001674	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
866344001675	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866344001676	nucleotide binding region [chemical binding]; other site
866344001677	ATP-binding site [chemical binding]; other site
866344001678	SEC-C motif; Region: SEC-C; pfam02810
866344001679	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
866344001680	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
866344001681	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866344001682	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
866344001683	aconitate hydratase 2; Region: acnB; TIGR00117
866344001684	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
866344001685	substrate binding site [chemical binding]; other site
866344001686	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
866344001687	substrate binding site [chemical binding]; other site
866344001688	ligand binding site [chemical binding]; other site
866344001689	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG1427
866344001690	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
866344001691	putative nucleotide binding site [chemical binding]; other site
866344001692	uridine monophosphate binding site [chemical binding]; other site
866344001693	homohexameric interface [polypeptide binding]; other site
866344001694	DNA-directed RNA polymerase, subunit K/omega [Transcription]; Region: RpoZ; COG1758
866344001695	(p)ppGpp synthetase, RelA/SpoT family; Region: spoT_relA; TIGR00691
866344001696	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
866344001697	Zn2+ binding site [ion binding]; other site
866344001698	Mg2+ binding site [ion binding]; other site
866344001699	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
866344001700	synthetase active site [active]
866344001701	NTP binding site [chemical binding]; other site
866344001702	metal binding site [ion binding]; metal-binding site
866344001703	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
866344001704	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
866344001705	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
866344001706	active site
866344001707	HIGH motif; other site
866344001708	dimer interface [polypeptide binding]; other site
866344001709	KMSKS motif; other site
866344001710	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866344001711	RNA binding surface [nucleotide binding]; other site
866344001712	Nitronate monooxygenase; Region: NMO; pfam03060
866344001713	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
866344001714	FMN binding site [chemical binding]; other site
866344001715	substrate binding site [chemical binding]; other site
866344001716	putative catalytic residue [active]
866344001717	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
866344001718	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
866344001719	active site
866344001720	metal binding site [ion binding]; metal-binding site
866344001721	flagellar biosynthetic protein FlhB; Region: flhB; TIGR00328
866344001722	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
866344001723	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
866344001724	GTP binding site; other site
866344001725	potential frameshift: common BLAST hit: gi|308182926|ref|YP_003927053.1| molybdenum cofactor biosynthesis protein A
866344001726	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
866344001727	FeS/SAM binding site; other site
866344001728	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
866344001729	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
866344001730	signal recognition particle-docking protein FtsY; Region: ftsY; TIGR00064
866344001731	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
866344001732	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212
866344001733	phosphodiesterase; Provisional; Region: PRK12704
866344001734	K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; Region: KH-I; cd00105
866344001735	nucleic acid binding region [nucleotide binding]; other site
866344001736	G-X-X-G motif; other site
866344001737	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
866344001738	Zn2+ binding site [ion binding]; other site
866344001739	Mg2+ binding site [ion binding]; other site
866344001740	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
866344001741	putative efflux protein, MATE family; Region: matE; TIGR00797
866344001742	Predicted permease [General function prediction only]; Region: COG2056
866344001743	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
866344001744	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
866344001745	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
866344001746	putative active site; other site
866344001747	catalytic triad [active]
866344001748	putative dimer interface [polypeptide binding]; other site
866344001749	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
866344001750	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
866344001751	putative ATP binding site [chemical binding]; other site
866344001752	putative substrate interface [chemical binding]; other site
866344001753	flagellar biosynthetic protein FliS; Region: fliS; TIGR00208
866344001754	flagellar capping protein; Validated; Region: fliD; PRK08453
866344001755	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
866344001756	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
866344001757	flagellar protein FlaG; Provisional; Region: PRK08452
866344001758	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
866344001759	Peptidase family M23; Region: Peptidase_M23; pfam01551
866344001760	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
866344001761	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
866344001762	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
866344001763	Walker A/P-loop; other site
866344001764	ATP binding site [chemical binding]; other site
866344001765	Q-loop/lid; other site
866344001766	ABC transporter signature motif; other site
866344001767	Walker B; other site
866344001768	D-loop; other site
866344001769	H-loop/switch region; other site
866344001770	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866344001771	S-adenosylmethionine binding site [chemical binding]; other site
866344001772	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
866344001773	Interdomain contacts; other site
866344001774	Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401
866344001775	Cytokine receptor motif; other site
866344001776	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
866344001777	Interdomain contacts; other site
866344001778	Cytokine receptor motif; other site
866344001779	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
866344001780	Interdomain contacts; other site
866344001781	Cytokine receptor motif; other site
866344001782	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
866344001783	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
866344001784	active site
866344001785	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
866344001786	G1 box; other site
866344001787	GTP/Mg2+ binding site [chemical binding]; other site
866344001788	G2 box; other site
866344001789	Predicted GTPase [General function prediction only]; Region: COG3596
866344001790	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
866344001791	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
866344001792	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
866344001793	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
866344001794	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866344001795	active site
866344001796	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
866344001797	nucleotide binding site/active site [active]
866344001798	HIT family signature motif; other site
866344001799	catalytic residue [active]
866344001800	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
866344001801	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866344001802	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
866344001803	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
866344001804	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
866344001805	ATP-grasp domain; Region: ATP-grasp_4; cl17255
866344001806	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
866344001807	tetramer interfaces [polypeptide binding]; other site
866344001808	binuclear metal-binding site [ion binding]; other site
866344001809	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
866344001810	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866344001811	catalytic residue [active]
866344001812	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236
866344001813	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866344001814	active site
866344001815	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
866344001816	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
866344001817	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866344001818	FeS/SAM binding site; other site
866344001819	cyclic beta-1,2-glucan ABC transporter; Provisional; Region: PRK13657
866344001820	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
866344001821	G1 box; other site
866344001822	GTP/Mg2+ binding site [chemical binding]; other site
866344001823	G2 box; other site
866344001824	Switch I region; other site
866344001825	G3 box; other site
866344001826	Switch II region; other site
866344001827	G4 box; other site
866344001828	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
866344001829	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
866344001830	Ligand Binding Site [chemical binding]; other site
866344001831	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
866344001832	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
866344001833	FMN binding site [chemical binding]; other site
866344001834	active site
866344001835	catalytic residues [active]
866344001836	substrate binding site [chemical binding]; other site
866344001837	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344001838	anaerobic c4-dicarboxylate membrane transporter family protein; Region: Dcu; TIGR00770
866344001839	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
866344001840	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
866344001841	active site
866344001842	homodimer interface [polypeptide binding]; other site
866344001843	homotetramer interface [polypeptide binding]; other site
866344001844	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
866344001845	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
866344001846	Lysine efflux permease [General function prediction only]; Region: COG1279
866344001847	DNA polymerase III subunits gamma and tau; Validated; Region: PRK08451
866344001848	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344001849	Walker A motif; other site
866344001850	ATP binding site [chemical binding]; other site
866344001851	DNA polymerase III subunit delta'; Validated; Region: PRK08485
866344001852	Walker B motif; other site
866344001853	arginine finger; other site
866344001854	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
866344001855	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
866344001856	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
866344001857	Walker A/P-loop; other site
866344001858	ATP binding site [chemical binding]; other site
866344001859	Q-loop/lid; other site
866344001860	ABC transporter signature motif; other site
866344001861	Walker B; other site
866344001862	D-loop; other site
866344001863	H-loop/switch region; other site
866344001864	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
866344001865	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
866344001866	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
866344001867	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
866344001868	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344001869	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
866344001870	Ligand Binding Site [chemical binding]; other site
866344001871	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
866344001872	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
866344001873	active site
866344001874	NTP binding site [chemical binding]; other site
866344001875	metal binding triad [ion binding]; metal-binding site
866344001876	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
866344001877	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
866344001878	dimer interface [polypeptide binding]; other site
866344001879	FMN binding site [chemical binding]; other site
866344001880	glutamylglutaminyl-tRNA synthetase; Provisional; Region: PRK12410
866344001881	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
866344001882	active site
866344001883	HIGH motif; other site
866344001884	nucleotide binding site [chemical binding]; other site
866344001885	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
866344001886	active site
866344001887	KMSKS motif; other site
866344001888	YGGT family; Region: YGGT; pfam02325
866344001889	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
866344001890	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
866344001891	N-acetyl-D-glucosamine binding site [chemical binding]; other site
866344001892	catalytic residue [active]
866344001893	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
866344001894	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
866344001895	active site
866344001896	tetramer interface; other site
866344001897	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
866344001898	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
866344001899	hinge; other site
866344001900	active site
866344001901	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
866344001902	Aspartase; Region: Aspartase; cd01357
866344001903	active sites [active]
866344001904	tetramer interface [polypeptide binding]; other site
866344001905	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
866344001906	ligand binding site [chemical binding]; other site
866344001907	active site
866344001908	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
866344001909	phosphoserine phosphatase SerB; Region: serB; TIGR00338
866344001910	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866344001911	motif II; other site
866344001912	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
866344001913	Ferritin-like domain; Region: Ferritin; pfam00210
866344001914	ferroxidase diiron center [ion binding]; other site
866344001915	hypothetical protein; Provisional; Region: PRK08444
866344001916	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866344001917	FeS/SAM binding site; other site
866344001918	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
866344001919	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866344001920	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866344001921	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866344001922	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866344001923	Surface antigen; Region: Bac_surface_Ag; pfam01103
866344001924	hypothetical protein; Provisional; Region: PRK08445
866344001925	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866344001926	FeS/SAM binding site; other site
866344001927	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
866344001928	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
866344001929	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
866344001930	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
866344001931	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
866344001932	GatB domain; Region: GatB_Yqey; smart00845
866344001933	SurA N-terminal domain; Region: SurA_N; pfam09312
866344001934	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
866344001935	Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module [General function prediction only]; Region: COG1439
866344001936	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
866344001937	RNA/DNA hybrid binding site [nucleotide binding]; other site
866344001938	active site
866344001939	ribonuclease III; Reviewed; Region: rnc; PRK00102
866344001940	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
866344001941	dimerization interface [polypeptide binding]; other site
866344001942	active site
866344001943	metal binding site [ion binding]; metal-binding site
866344001944	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
866344001945	dsRNA binding site [nucleotide binding]; other site
866344001946	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
866344001947	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
866344001948	Tetramer interface [polypeptide binding]; other site
866344001949	active site
866344001950	FMN-binding site [chemical binding]; other site
866344001951	Protein of unknown function (DUF2603); Region: DUF2603; pfam10788
866344001952	oxygen-independent coproporphyrinogen III oxidase; Region: hemN; TIGR00538
866344001953	HemN C-terminal domain; Region: HemN_C; pfam06969
866344001954	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
866344001955	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866344001956	Cysteine-rich domain; Region: CCG; pfam02754
866344001957	Cysteine-rich domain; Region: CCG; pfam02754
866344001958	Predicted helicase [General function prediction only]; Region: COG4889
866344001959	Restriction endonuclease; Region: Mrr_cat_2; pfam13156
866344001960	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866344001961	ATP binding site [chemical binding]; other site
866344001962	putative Mg++ binding site [ion binding]; other site
866344001963	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866344001964	nucleotide binding region [chemical binding]; other site
866344001965	ATP-binding site [chemical binding]; other site
866344001966	Predicted helicase [General function prediction only]; Region: COG4889
866344001967	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344001968	aspartate aminotransferase; Provisional; Region: PRK05764
866344001969	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
866344001970	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866344001971	homodimer interface [polypeptide binding]; other site
866344001972	catalytic residue [active]
866344001973	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
866344001974	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
866344001975	active site
866344001976	DNA binding site [nucleotide binding]
866344001977	Int/Topo IB signature motif; other site
866344001978	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
866344001979	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
866344001980	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
866344001981	DNA binding site [nucleotide binding]
866344001982	active site
866344001983	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
866344001984	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
866344001985	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
866344001986	active site
866344001987	DNA binding site [nucleotide binding]
866344001988	Int/Topo IB signature motif; other site
866344001989	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
866344001990	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
866344001991	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
866344001992	DNA binding site [nucleotide binding]
866344001993	active site
866344001994	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
866344001995	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
866344001996	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
866344001997	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
866344001998	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08447
866344001999	ATP cone domain; Region: ATP-cone; pfam03477
866344002000	Class I ribonucleotide reductase; Region: RNR_I; cd01679
866344002001	active site
866344002002	dimer interface [polypeptide binding]; other site
866344002003	catalytic residues [active]
866344002004	effector binding site; other site
866344002005	R2 peptide binding site; other site
866344002006	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14359
866344002007	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
866344002008	Substrate binding site; other site
866344002009	Mg++ binding site; other site
866344002010	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
866344002011	active site
866344002012	substrate binding site [chemical binding]; other site
866344002013	CoA binding site [chemical binding]; other site
866344002014	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
866344002015	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
866344002016	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
866344002017	N-terminal plug; other site
866344002018	ligand-binding site [chemical binding]; other site
866344002019	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
866344002020	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
866344002021	G1 box; other site
866344002022	GTP/Mg2+ binding site [chemical binding]; other site
866344002023	Switch I region; other site
866344002024	G2 box; other site
866344002025	G3 box; other site
866344002026	Switch II region; other site
866344002027	G4 box; other site
866344002028	G5 box; other site
866344002029	Nucleoside recognition; Region: Gate; pfam07670
866344002030	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
866344002031	Nucleoside recognition; Region: Gate; pfam07670
866344002032	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
866344002033	active site
866344002034	catalytic site [active]
866344002035	substrate binding site [chemical binding]; other site
866344002036	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108
866344002037	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866344002038	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344002039	CfrBI restriction endonuclease; Region: RE_CfrBI; pfam09516
866344002040	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB [DNA replication, recombination, and repair]; Region: COG3298
866344002041	putative acyltransferase; Provisional; Region: PRK05790
866344002042	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
866344002043	dimer interface [polypeptide binding]; other site
866344002044	active site
866344002045	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
866344002046	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
866344002047	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
866344002048	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
866344002049	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
866344002050	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
866344002051	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
866344002052	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
866344002053	Hydantoinase B/oxoprolinase; Region: Hydantoinase_B; pfam02538
866344002054	Acetone carboxylase, gamma subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcxC; COG4647
866344002055	Acetone carboxylase gamma subunit; Region: Acetone_carb_G; pfam08882
866344002056	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
866344002057	DNA gyrase subunit A; Validated; Region: PRK05560
866344002058	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
866344002059	CAP-like domain; other site
866344002060	active site
866344002061	primary dimer interface [polypeptide binding]; other site
866344002062	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866344002063	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866344002064	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866344002065	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866344002066	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866344002067	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866344002068	Response regulator receiver domain; Region: Response_reg; pfam00072
866344002069	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866344002070	active site
866344002071	phosphorylation site [posttranslational modification]
866344002072	intermolecular recognition site; other site
866344002073	dimerization interface [polypeptide binding]; other site
866344002074	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344002075	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
866344002076	Walker A motif; other site
866344002077	ATP binding site [chemical binding]; other site
866344002078	Walker B motif; other site
866344002079	arginine finger; other site
866344002080	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
866344002081	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
866344002082	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
866344002083	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
866344002084	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344002085	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
866344002086	MraW methylase family; Region: Methyltransf_5; cl17771
866344002087	Uncharacterized conserved protein [Function unknown]; Region: COG1912
866344002088	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
866344002089	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
866344002090	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344002091	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
866344002092	nickel binding site [ion binding]; other site
866344002093	putative substrate-binding site; other site
866344002094	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
866344002095	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
866344002096	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
866344002097	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
866344002098	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
866344002099	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
866344002100	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866344002101	Protein of unknown function DUF262; Region: DUF262; pfam03235
866344002102	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866344002103	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866344002104	Sel1-like repeats; Region: SEL1; smart00671
866344002105	Sel1-like repeats; Region: SEL1; smart00671
866344002106	Sel1 repeat; Region: Sel1; cl02723
866344002107	Sel1-like repeats; Region: SEL1; smart00671
866344002108	Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Region: DapD; COG2171
866344002109	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
866344002110	putative trimer interface [polypeptide binding]; other site
866344002111	putative CoA binding site [chemical binding]; other site
866344002112	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
866344002113	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
866344002114	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
866344002115	hypothetical protein; Provisional; Region: PRK05839
866344002116	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
866344002117	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866344002118	homodimer interface [polypeptide binding]; other site
866344002119	catalytic residue [active]
866344002120	UDP-N-acetylmuramate--alanine ligase; Region: murC; TIGR01082
866344002121	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
866344002122	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866344002123	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866344002124	MutS2 family protein; Region: mutS2; TIGR01069
866344002125	ATPase domain of DNA mismatch repair MUTS family; Region: MUTSac; smart00534
866344002126	Walker A/P-loop; other site
866344002127	ATP binding site [chemical binding]; other site
866344002128	Q-loop/lid; other site
866344002129	ABC transporter signature motif; other site
866344002130	Walker B; other site
866344002131	D-loop; other site
866344002132	H-loop/switch region; other site
866344002133	Smr domain; Region: Smr; pfam01713
866344002134	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
866344002135	dimer interface [polypeptide binding]; other site
866344002136	substrate binding site [chemical binding]; other site
866344002137	metal binding sites [ion binding]; metal-binding site
866344002138	Glycosyltransferase involved in LPS biosynthesis [Cell envelope biogenesis, outer membrane]; Region: COG3306
866344002139	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
866344002140	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
866344002141	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
866344002142	adenylate kinase; Reviewed; Region: adk; PRK00279
866344002143	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
866344002144	AMP-binding site [chemical binding]; other site
866344002145	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
866344002146	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
866344002147	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
866344002148	dimer interface [polypeptide binding]; other site
866344002149	anticodon binding site; other site
866344002150	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
866344002151	homodimer interface [polypeptide binding]; other site
866344002152	motif 1; other site
866344002153	active site
866344002154	motif 2; other site
866344002155	GAD domain; Region: GAD; pfam02938
866344002156	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
866344002157	active site
866344002158	motif 3; other site
866344002159	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
866344002160	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
866344002161	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866344002162	active site
866344002163	phosphorylation site [posttranslational modification]
866344002164	intermolecular recognition site; other site
866344002165	dimerization interface [polypeptide binding]; other site
866344002166	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
866344002167	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
866344002168	nucleotide binding pocket [chemical binding]; other site
866344002169	K-X-D-G motif; other site
866344002170	catalytic site [active]
866344002171	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
866344002172	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
866344002173	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
866344002174	Dimer interface [polypeptide binding]; other site
866344002175	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866344002176	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
866344002177	Walker A/P-loop; other site
866344002178	ATP binding site [chemical binding]; other site
866344002179	Q-loop/lid; other site
866344002180	ABC transporter signature motif; other site
866344002181	Walker B; other site
866344002182	D-loop; other site
866344002183	H-loop/switch region; other site
866344002184	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866344002185	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
866344002186	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866344002187	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866344002188	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866344002189	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
866344002190	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866344002191	Autotransporter beta-domain; Region: Autotransporter; pfam03797
866344002192	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344002193	AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873
866344002194	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866344002195	HlyD family secretion protein; Region: HlyD_3; pfam13437
866344002196	Outer membrane efflux protein; Region: OEP; pfam02321
866344002197	Outer membrane efflux protein; Region: OEP; pfam02321
866344002198	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
866344002199	substrate binding site [chemical binding]; other site
866344002200	active site
866344002201	3-methyladenine DNA glycosylase; Provisional; Region: PRK13913
866344002202	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
866344002203	minor groove reading motif; other site
866344002204	helix-hairpin-helix signature motif; other site
866344002205	active site
866344002206	flagellin A; Reviewed; Region: PRK12584
866344002207	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
866344002208	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
866344002209	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
866344002210	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
866344002211	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
866344002212	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
866344002213	Walker A/P-loop; other site
866344002214	ATP binding site [chemical binding]; other site
866344002215	Q-loop/lid; other site
866344002216	ABC transporter signature motif; other site
866344002217	Walker B; other site
866344002218	D-loop; other site
866344002219	H-loop/switch region; other site
866344002220	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
866344002221	dimer interface [polypeptide binding]; other site
866344002222	putative CheW interface [polypeptide binding]; other site
866344002223	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
866344002224	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
866344002225	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
866344002226	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866344002227	catalytic residue [active]
866344002228	Transglycosylase; Region: Transgly; pfam00912
866344002229	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
866344002230	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
866344002231	tumor necrosis factor alpha-inducing protein; Reviewed; Region: PRK12303
866344002232	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
866344002233	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
866344002234	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Region: HAD-SF-IA-v1; TIGR01549
866344002235	2-oxoglutarate-acceptor oxidoreductase subunit OorC; Reviewed; Region: oorC; PRK08441
866344002236	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
866344002237	2-oxoglutarate-acceptor oxidoreductase subunit OorB; Reviewed; Region: oorB; PRK09628
866344002238	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
866344002239	TPP-binding site [chemical binding]; other site
866344002240	2-oxoglutarate-acceptor oxidoreductase subunit OorA; Reviewed; Region: oorA; PRK09627
866344002241	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
866344002242	dimer interface [polypeptide binding]; other site
866344002243	PYR/PP interface [polypeptide binding]; other site
866344002244	TPP binding site [chemical binding]; other site
866344002245	substrate binding site [chemical binding]; other site
866344002246	2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed; Region: oorD; PRK09626
866344002247	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
866344002248	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
866344002249	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
866344002250	dimerization interface [polypeptide binding]; other site
866344002251	Protein of unknown function; Region: DUF3971; pfam13116
866344002252	AsmA-like C-terminal region; Region: AsmA_1; pfam13109
866344002253	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
866344002254	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
866344002255	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
866344002256	minor groove reading motif; other site
866344002257	helix-hairpin-helix signature motif; other site
866344002258	substrate binding pocket [chemical binding]; other site
866344002259	active site
866344002260	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
866344002261	flagellar motor switch protein; Validated; Region: PRK08433
866344002262	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
866344002263	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
866344002264	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
866344002265	active site
866344002266	substrate binding pocket [chemical binding]; other site
866344002267	dimer interface [polypeptide binding]; other site
866344002268	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
866344002269	BNR repeat-like domain; Region: BNR_2; pfam13088
866344002270	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
866344002271	Sulfatase; Region: Sulfatase; pfam00884
866344002272	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14191
866344002273	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
866344002274	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
866344002275	homodimer interface [polypeptide binding]; other site
866344002276	NADP binding site [chemical binding]; other site
866344002277	substrate binding site [chemical binding]; other site
866344002278	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
866344002279	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
866344002280	Catalytic site [active]
866344002281	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
866344002282	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
866344002283	Peptidase family M50; Region: Peptidase_M50; pfam02163
866344002284	active site
866344002285	putative substrate binding region [chemical binding]; other site
866344002286	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
866344002287	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
866344002288	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866344002289	active site
866344002290	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
866344002291	multifunctional aminopeptidase A; Provisional; Region: PRK00913
866344002292	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
866344002293	interface (dimer of trimers) [polypeptide binding]; other site
866344002294	Substrate-binding/catalytic site; other site
866344002295	Zn-binding sites [ion binding]; other site
866344002296	GTP-binding protein YchF; Reviewed; Region: PRK09601
866344002297	YchF GTPase; Region: YchF; cd01900
866344002298	G1 box; other site
866344002299	GTP/Mg2+ binding site [chemical binding]; other site
866344002300	Switch I region; other site
866344002301	G2 box; other site
866344002302	Switch II region; other site
866344002303	G3 box; other site
866344002304	G4 box; other site
866344002305	G5 box; other site
866344002306	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
866344002307	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866344002308	FeS/SAM binding site; other site
866344002309	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
866344002310	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
866344002311	Domain of unknown function DUF20; Region: UPF0118; pfam01594
866344002312	diaminopimelate epimerase; Region: DapF; TIGR00652
866344002313	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
866344002314	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
866344002315	Predicted membrane protein [Function unknown]; Region: COG3059
866344002316	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
866344002317	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
866344002318	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
866344002319	NAD(P) binding site [chemical binding]; other site
866344002320	active site
866344002321	acyl carrier protein; Provisional; Region: acpP; PRK00982
866344002322	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK08439
866344002323	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
866344002324	dimer interface [polypeptide binding]; other site
866344002325	active site
866344002326	acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Region: accA; TIGR00513
866344002327	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
866344002328	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
866344002329	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
866344002330	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
866344002331	Predicted methyltransferases [General function prediction only]; Region: COG0313
866344002332	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
866344002333	putative SAM binding site [chemical binding]; other site
866344002334	putative homodimer interface [polypeptide binding]; other site
866344002335	Ribosomal protein L31; Region: Ribosomal_L31; pfam01197
866344002336	transcription termination factor Rho; Provisional; Region: rho; PRK09376
866344002337	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
866344002338	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
866344002339	RNA binding site [nucleotide binding]; other site
866344002340	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
866344002341	multimer interface [polypeptide binding]; other site
866344002342	Walker A motif; other site
866344002343	ATP binding site [chemical binding]; other site
866344002344	Walker B motif; other site
866344002345	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
866344002346	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
866344002347	CagA exotoxin; Region: CagA; pfam03507
866344002348	CagA exotoxin; Region: CagA; pfam03507
866344002349	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
866344002350	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
866344002351	prolyl-tRNA synthetase; Provisional; Region: PRK08661
866344002352	Cag pathogenicity island protein Cag12; Region: Cag12; pfam13117
866344002353	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
866344002354	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
866344002355	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
866344002356	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
866344002357	VirB7 interaction site; other site
866344002358	DC-EC Repeat; Region: CagY_M; pfam07337
866344002359	DC-EC Repeat; Region: CagY_M; pfam07337
866344002360	DC-EC Repeat; Region: CagY_M; pfam07337
866344002361	DC-EC Repeat; Region: CagY_M; pfam07337
866344002362	DC-EC Repeat; Region: CagY_M; pfam07337
866344002363	DC-EC Repeat; Region: CagY_M; pfam07337
866344002364	DC-EC Repeat; Region: CagY_M; pfam07337
866344002365	DC-EC Repeat; Region: CagY_M; pfam07337
866344002366	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
866344002367	CagZ; Region: CagZ; pfam09053
866344002368	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
866344002369	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
866344002370	ATP binding site [chemical binding]; other site
866344002371	Walker A motif; other site
866344002372	hexamer interface [polypeptide binding]; other site
866344002373	Walker B motif; other site
866344002374	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
866344002375	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
866344002376	Walker A motif; other site
866344002377	ATP binding site [chemical binding]; other site
866344002378	Walker B motif; other site
866344002379	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866344002380	Sel1-like repeats; Region: SEL1; smart00671
866344002381	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
866344002382	GTPase [General function prediction only]; Region: Era; COG1159
866344002383	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
866344002384	G1 box; other site
866344002385	GTP/Mg2+ binding site [chemical binding]; other site
866344002386	Switch I region; other site
866344002387	G2 box; other site
866344002388	Switch II region; other site
866344002389	G3 box; other site
866344002390	G4 box; other site
866344002391	G5 box; other site
866344002392	KH domain; Region: KH_2; pfam07650
866344002393	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
866344002394	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344002395	Walker A motif; other site
866344002396	ATP binding site [chemical binding]; other site
866344002397	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
866344002398	Walker B motif; other site
866344002399	arginine finger; other site
866344002400	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
866344002401	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
866344002402	active site
866344002403	HslU subunit interaction site [polypeptide binding]; other site
866344002404	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
866344002405	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
866344002406	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
866344002407	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866344002408	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866344002409	Uncharacterized conserved protein [Function unknown]; Region: COG3586
866344002410	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866344002411	Protein of unknown function DUF262; Region: DUF262; pfam03235
866344002412	glutamine synthetase, type I; Region: GlnA; TIGR00653
866344002413	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
866344002414	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
866344002415	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
866344002416	dihydrodipicolinate reductase; Region: dapB; TIGR00036
866344002417	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
866344002418	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
866344002419	FAD binding domain; Region: FAD_binding_4; pfam01565
866344002420	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
866344002421	Protein-interacting Bro1-like domain of mammalian Alix and related domains; Region: BRO1_Alix_like; cl14649
866344002422	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
866344002423	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
866344002424	dimer interface [polypeptide binding]; other site
866344002425	ADP-ribose binding site [chemical binding]; other site
866344002426	active site
866344002427	nudix motif; other site
866344002428	metal binding site [ion binding]; metal-binding site
866344002429	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
866344002430	Peptidase family M23; Region: Peptidase_M23; pfam01551
866344002431	R.Pab1 restriction endonuclease; Region: RE_R_Pab1; pfam09522
866344002432	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
866344002433	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866344002434	Mg2+ binding site [ion binding]; other site
866344002435	G-X-G motif; other site
866344002436	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
866344002437	anchoring element; other site
866344002438	dimer interface [polypeptide binding]; other site
866344002439	ATP binding site [chemical binding]; other site
866344002440	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
866344002441	active site
866344002442	putative metal-binding site [ion binding]; other site
866344002443	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
866344002444	DNA polymerase III, beta subunit; Region: dnan; TIGR00663
866344002445	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
866344002446	putative DNA binding surface [nucleotide binding]; other site
866344002447	dimer interface [polypeptide binding]; other site
866344002448	beta-clamp/translesion DNA polymerase binding surface; other site
866344002449	beta-clamp/clamp loader binding surface; other site
866344002450	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
866344002451	dimerization interface [polypeptide binding]; other site
866344002452	substrate binding site [chemical binding]; other site
866344002453	active site
866344002454	calcium binding site [ion binding]; other site
866344002455	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
866344002456	Na2 binding site [ion binding]; other site
866344002457	putative substrate binding site 1 [chemical binding]; other site
866344002458	Na binding site 1 [ion binding]; other site
866344002459	putative substrate binding site 2 [chemical binding]; other site
866344002460	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
866344002461	Na2 binding site [ion binding]; other site
866344002462	putative substrate binding site 1 [chemical binding]; other site
866344002463	Na binding site 1 [ion binding]; other site
866344002464	putative substrate binding site 2 [chemical binding]; other site
866344002465	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
866344002466	active site
866344002467	Protein of unknown function (DUF493); Region: DUF493; pfam04359
866344002468	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03815
866344002469	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866344002470	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866344002471	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
866344002472	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
866344002473	Mg++ binding site [ion binding]; other site
866344002474	putative catalytic motif [active]
866344002475	putative substrate binding site [chemical binding]; other site
866344002476	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
866344002477	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
866344002478	Cation transport protein; Region: TrkH; cl17365
866344002479	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
866344002480	TrkA-N domain; Region: TrkA_N; pfam02254
866344002481	TrkA-C domain; Region: TrkA_C; pfam02080
866344002482	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
866344002483	Holliday junction DNA helicase, RuvA subunit; Region: ruvA; TIGR00084
866344002484	RuvA N terminal domain; Region: RuvA_N; pfam01330
866344002485	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
866344002486	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
866344002487	MviN-like protein; Region: MVIN; pfam03023
866344002488	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
866344002489	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
866344002490	active site
866344002491	HIGH motif; other site
866344002492	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
866344002493	KMSKS motif; other site
866344002494	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
866344002495	tRNA binding surface [nucleotide binding]; other site
866344002496	anticodon binding site; other site
866344002497	Vacuolating cyotoxin; Region: VacA; pfam02691
866344002498	Autotransporter beta-domain; Region: Autotransporter; pfam03797
866344002499	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
866344002500	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
866344002501	Walker A/P-loop; other site
866344002502	ATP binding site [chemical binding]; other site
866344002503	Q-loop/lid; other site
866344002504	ABC transporter signature motif; other site
866344002505	Walker B; other site
866344002506	D-loop; other site
866344002507	H-loop/switch region; other site
866344002508	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
866344002509	ABC-ATPase subunit  interface; other site
866344002510	dimer interface [polypeptide binding]; other site
866344002511	putative PBP binding regions; other site
866344002512	short chain dehydrogenase; Validated; Region: PRK06182
866344002513	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
866344002514	NADP binding site [chemical binding]; other site
866344002515	active site
866344002516	steroid binding site; other site
866344002517	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
866344002518	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
866344002519	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344002520	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
866344002521	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
866344002522	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypC; COG0298
866344002523	hydrogenase accessory protein HypB; Region: hypB; TIGR00073
866344002524	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
866344002525	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
866344002526	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
866344002527	propionate/acetate kinase; Provisional; Region: PRK12379
866344002528	BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; Region: Pta; COG0857
866344002529	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
866344002530	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
866344002531	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK05842
866344002532	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
866344002533	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
866344002534	flagellar hook protein FlgE; Validated; Region: flgE; PRK05841
866344002535	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
866344002536	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
866344002537	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866344002538	S-adenosylmethionine binding site [chemical binding]; other site
866344002539	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
866344002540	Part of AAA domain; Region: AAA_19; pfam13245
866344002541	Family description; Region: UvrD_C_2; pfam13538
866344002542	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344002543	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344002544	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866344002545	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
866344002546	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866344002547	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866344002548	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
866344002549	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
866344002550	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
866344002551	ATP-grasp domain; Region: ATP-grasp_4; cl17255
866344002552	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
866344002553	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
866344002554	ATP-grasp domain; Region: ATP-grasp_4; cl17255
866344002555	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
866344002556	IMP binding site; other site
866344002557	dimer interface [polypeptide binding]; other site
866344002558	interdomain contacts; other site
866344002559	partial ornithine binding site; other site
866344002560	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
866344002561	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
866344002562	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
866344002563	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
866344002564	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
866344002565	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866344002566	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
866344002567	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866344002568	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
866344002569	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866344002570	Autotransporter beta-domain; Region: Autotransporter; pfam03797
866344002571	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344002572	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
866344002573	active site 1 [active]
866344002574	dimer interface [polypeptide binding]; other site
866344002575	hexamer interface [polypeptide binding]; other site
866344002576	active site 2 [active]
866344002577	recombination protein RecR; Region: recR; TIGR00615
866344002578	RecR protein; Region: RecR; pfam02132
866344002579	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
866344002580	putative active site [active]
866344002581	putative metal-binding site [ion binding]; other site
866344002582	tetramer interface [polypeptide binding]; other site
866344002583	tRNA pseudouridine synthase, TruD family; Region: tRNA_TruD_broad; TIGR00094
866344002584	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
866344002585	Permutation of conserved domain; other site
866344002586	active site
866344002587	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
866344002588	heat shock protein HtpX; Provisional; Region: PRK02870
866344002589	GTP cyclohydrolase I; Region: folE; TIGR00063
866344002590	GTP cyclohydrolase I; Provisional; Region: PLN03044
866344002591	active site
866344002592	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
866344002593	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
866344002594	substrate binding pocket [chemical binding]; other site
866344002595	chain length determination region; other site
866344002596	substrate-Mg2+ binding site; other site
866344002597	catalytic residues [active]
866344002598	aspartate-rich region 1; other site
866344002599	active site lid residues [active]
866344002600	aspartate-rich region 2; other site
866344002601	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
866344002602	6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Region: COG0720
866344002603	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
866344002604	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
866344002605	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
866344002606	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866344002607	Coenzyme A binding pocket [chemical binding]; other site
866344002608	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344002609	potential frameshift: common BLAST hit: gi|188527759|ref|YP_001910446.1| proline and betaine transporter
866344002610	metabolite-proton symporter; Region: 2A0106; TIGR00883
866344002611	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
866344002612	Protein of unknown function DUF262; Region: DUF262; pfam03235
866344002613	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866344002614	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
866344002615	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866344002616	dimer interface [polypeptide binding]; other site
866344002617	conserved gate region; other site
866344002618	putative PBP binding loops; other site
866344002619	ABC-ATPase subunit interface; other site
866344002620	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
866344002621	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866344002622	substrate binding pocket [chemical binding]; other site
866344002623	membrane-bound complex binding site; other site
866344002624	hinge residues; other site
866344002625	alanine racemase; Region: alr; TIGR00492
866344002626	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
866344002627	active site
866344002628	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866344002629	dimer interface [polypeptide binding]; other site
866344002630	substrate binding site [chemical binding]; other site
866344002631	catalytic residues [active]
866344002632	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
866344002633	amino acid carrier protein; Region: agcS; TIGR00835
866344002634	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
866344002635	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
866344002636	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
866344002637	homotrimer interaction site [polypeptide binding]; other site
866344002638	putative active site [active]
866344002639	TRL-like protein family; Region: TRL; pfam13146
866344002640	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
866344002641	Predicted SPOUT methyltransferase; Region: SPOUT_MTase; cl00679
866344002642	acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Region: accD; TIGR00515
866344002643	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
866344002644	putative recombination protein RecO; Provisional; Region: PRK13908
866344002645	competence/damage-inducible protein CinA C-terminal domain; Region: cinA_cterm; TIGR00199
866344002646	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
866344002647	dimer interface [polypeptide binding]; other site
866344002648	FMN binding site [chemical binding]; other site
866344002649	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
866344002650	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
866344002651	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
866344002652	active site
866344002653	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
866344002654	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
866344002655	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
866344002656	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
866344002657	Putative zinc ribbon domain; Region: DUF164; pfam02591
866344002658	dinuclear metal center protein, YbgI/SA1388 family; Region: YbgI_SA1388; TIGR00486
866344002659	Uncharacterized conserved protein [Function unknown]; Region: COG0327
866344002660	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
866344002661	dimer interface [polypeptide binding]; other site
866344002662	motif 1; other site
866344002663	active site
866344002664	motif 2; other site
866344002665	motif 3; other site
866344002666	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
866344002667	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
866344002668	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
866344002669	Dynamin family; Region: Dynamin_N; pfam00350
866344002670	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
866344002671	G3 box; other site
866344002672	Switch II region; other site
866344002673	GTP/Mg2+ binding site [chemical binding]; other site
866344002674	G4 box; other site
866344002675	G5 box; other site
866344002676	Probable transposase; Region: OrfB_IS605; pfam01385
866344002677	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
866344002678	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
866344002679	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
866344002680	potential frameshift: common BLAST hit: gi|383750179|ref|YP_005425282.1| transposase A-OrfA
866344002681	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
866344002682	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
866344002683	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
866344002684	DNA binding residues [nucleotide binding]
866344002685	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
866344002686	catalytic residues [active]
866344002687	catalytic nucleophile [active]
866344002688	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
866344002689	G1 box; other site
866344002690	GTP/Mg2+ binding site [chemical binding]; other site
866344002691	G2 box; other site
866344002692	Switch I region; other site
866344002693	G3 box; other site
866344002694	Switch II region; other site
866344002695	Uncharacterized virulence-associated protein D [Function unknown]; Region: VapD; COG3309
866344002696	Protein of unknown function (DUF3240); Region: DUF3240; pfam11582
866344002697	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
866344002698	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
866344002699	Outer membrane efflux protein; Region: OEP; pfam02321
866344002700	Outer membrane efflux protein; Region: OEP; pfam02321
866344002701	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
866344002702	phosphoglyceromutase; Provisional; Region: PRK05434
866344002703	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
866344002704	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; Region: gatC; TIGR00135
866344002705	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
866344002706	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
866344002707	inhibitor-cofactor binding pocket; inhibition site
866344002708	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866344002709	catalytic residue [active]
866344002710	SurA N-terminal domain; Region: SurA_N_3; cl07813
866344002711	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
866344002712	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
866344002713	cell division protein FtsA; Region: ftsA; TIGR01174
866344002714	Cell division protein FtsA; Region: FtsA; smart00842
866344002715	Cell division protein FtsA; Region: FtsA; pfam14450
866344002716	cell division protein FtsZ; Validated; Region: PRK09330
866344002717	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
866344002718	nucleotide binding site [chemical binding]; other site
866344002719	SulA interaction site; other site
866344002720	Mechanosensitive ion channel; Region: MS_channel; pfam00924
866344002721	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866344002722	Protein of unknown function DUF262; Region: DUF262; pfam03235
866344002723	Protein of unknown function DUF262; Region: DUF262; pfam03235
866344002724	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866344002725	Single-stranded DNA-specific exonuclease [DNA replication, recombination, and repair]; Region: RecJ; COG0608
866344002726	DHH family; Region: DHH; pfam01368
866344002727	Single-stranded DNA-specific exonuclease [DNA replication, recombination, and repair]; Region: RecJ; COG0608
866344002728	Pleckstrin homology-like domain; Region: PH-like; cl17171
866344002729	Peptidase family M23; Region: Peptidase_M23; pfam01551
866344002730	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
866344002731	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
866344002732	active site
866344002733	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866344002734	catalytic residues [active]
866344002735	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
866344002736	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
866344002737	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
866344002738	putative ADP-binding pocket [chemical binding]; other site
866344002739	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
866344002740	active site 2 [active]
866344002741	active site 1 [active]
866344002742	Methyltransferase domain; Region: Methyltransf_23; pfam13489
866344002743	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866344002744	S-adenosylmethionine binding site [chemical binding]; other site
866344002745	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
866344002746	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
866344002747	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
866344002748	active site
866344002749	HIGH motif; other site
866344002750	KMSKS motif; other site
866344002751	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
866344002752	anticodon binding site; other site
866344002753	tRNA binding surface [nucleotide binding]; other site
866344002754	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
866344002755	dimer interface [polypeptide binding]; other site
866344002756	putative tRNA-binding site [nucleotide binding]; other site
866344002757	Mycolic acid cyclopropane synthetase; Region: CMAS; pfam02353
866344002758	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866344002759	S-adenosylmethionine binding site [chemical binding]; other site
866344002760	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
866344002761	Mechanosensitive ion channel; Region: MS_channel; pfam00924
866344002762	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
866344002763	GMP synthase; Reviewed; Region: guaA; PRK00074
866344002764	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
866344002765	AMP/PPi binding site [chemical binding]; other site
866344002766	candidate oxyanion hole; other site
866344002767	catalytic triad [active]
866344002768	potential glutamine specificity residues [chemical binding]; other site
866344002769	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
866344002770	ATP Binding subdomain [chemical binding]; other site
866344002771	Ligand Binding sites [chemical binding]; other site
866344002772	Dimerization subdomain; other site
866344002773	potential frameshift: common BLAST hit: gi|308183150|ref|YP_003927277.1| biotin sulfoxide reductase (bisC)
866344002774	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866344002775	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
866344002776	molybdopterin cofactor binding site; other site
866344002777	potential frameshift: common BLAST hit: gi|308183150|ref|YP_003927277.1| biotin sulfoxide reductase (bisC)
866344002778	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866344002779	potential frameshift: common BLAST hit: gi|308183150|ref|YP_003927277.1| biotin sulfoxide reductase (bisC)
866344002780	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866344002781	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866344002782	molybdopterin cofactor binding site; other site
866344002783	Protein of unknown function (DUF3972); Region: DUF3972; pfam13118
866344002784	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
866344002785	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
866344002786	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866344002787	catalytic residue [active]
866344002788	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
866344002789	nucleotide binding site/active site [active]
866344002790	HIT family signature motif; other site
866344002791	catalytic residue [active]
866344002792	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
866344002793	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
866344002794	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
866344002795	dimer interface [polypeptide binding]; other site
866344002796	motif 1; other site
866344002797	active site
866344002798	motif 2; other site
866344002799	motif 3; other site
866344002800	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
866344002801	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
866344002802	putative tRNA-binding site [nucleotide binding]; other site
866344002803	tRNA synthetase B5 domain; Region: B5; pfam03484
866344002804	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
866344002805	dimer interface [polypeptide binding]; other site
866344002806	motif 1; other site
866344002807	motif 3; other site
866344002808	motif 2; other site
866344002809	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
866344002810	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
866344002811	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
866344002812	hinge; other site
866344002813	active site
866344002814	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
866344002815	LytB protein; Region: LYTB; pfam02401
866344002816	ribosomal protein S1; Region: rpsA; TIGR00717
866344002817	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
866344002818	RNA binding site [nucleotide binding]; other site
866344002819	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
866344002820	RNA binding site [nucleotide binding]; other site
866344002821	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
866344002822	RNA binding site [nucleotide binding]; other site
866344002823	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
866344002824	RNA binding site [nucleotide binding]; other site
866344002825	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
866344002826	RNA binding site [nucleotide binding]; other site
866344002827	D-3-phosphoglycerate dehydrogenase; Region: PGDH; TIGR01327
866344002828	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
866344002829	ligand binding site [chemical binding]; other site
866344002830	NAD binding site [chemical binding]; other site
866344002831	dimerization interface [polypeptide binding]; other site
866344002832	catalytic site [active]
866344002833	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
866344002834	putative L-serine binding site [chemical binding]; other site
866344002835	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
866344002836	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
866344002837	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
866344002838	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866344002839	catalytic residue [active]
866344002840	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
866344002841	putative active site [active]
866344002842	putative metal binding site [ion binding]; other site
866344002843	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
866344002844	putative CheA interaction surface; other site
866344002845	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
866344002846	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866344002847	active site
866344002848	phosphorylation site [posttranslational modification]
866344002849	intermolecular recognition site; other site
866344002850	dimerization interface [polypeptide binding]; other site
866344002851	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
866344002852	putative binding surface; other site
866344002853	active site
866344002854	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
866344002855	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
866344002856	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866344002857	ATP binding site [chemical binding]; other site
866344002858	Mg2+ binding site [ion binding]; other site
866344002859	G-X-G motif; other site
866344002860	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
866344002861	Response regulator receiver domain; Region: Response_reg; pfam00072
866344002862	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866344002863	active site
866344002864	phosphorylation site [posttranslational modification]
866344002865	intermolecular recognition site; other site
866344002866	dimerization interface [polypeptide binding]; other site
866344002867	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
866344002868	putative CheA interaction surface; other site
866344002869	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
866344002870	dimer interface [polypeptide binding]; other site
866344002871	catalytic triad [active]
866344002872	peroxidatic and resolving cysteines [active]
866344002873	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
866344002874	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
866344002875	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
866344002876	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866344002877	S-adenosylmethionine binding site [chemical binding]; other site
866344002878	primosome assembly protein PriA; Validated; Region: PRK05580
866344002879	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866344002880	ATP binding site [chemical binding]; other site
866344002881	putative Mg++ binding site [ion binding]; other site
866344002882	helicase superfamily c-terminal domain; Region: HELICc; smart00490
866344002883	Sporulation related domain; Region: SPOR; pfam05036
866344002884	potential frameshift: common BLAST hit: gi|254779626|ref|YP_003057732.1| metalloprotease; membrane protein
866344002885	Peptidase family M48; Region: Peptidase_M48; pfam01435
866344002886	HemK family putative methylases; Region: hemK_fam; TIGR00536
866344002887	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
866344002888	glutamate dehydrogenase; Provisional; Region: PRK09414
866344002889	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
866344002890	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
866344002891	NAD(P) binding site [chemical binding]; other site
866344002892	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
866344002893	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
866344002894	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
866344002895	SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide...; Region: SoxW; cd02951
866344002896	catalytic residues [active]
866344002897	ferrochelatase; Region: hemH; TIGR00109
866344002898	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
866344002899	C-terminal domain interface [polypeptide binding]; other site
866344002900	active site
866344002901	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
866344002902	active site
866344002903	N-terminal domain interface [polypeptide binding]; other site
866344002904	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
866344002905	RNA methyltransferase, RsmE family; Region: TIGR00046
866344002906	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344002907	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
866344002908	trimer interface [polypeptide binding]; other site
866344002909	active site
866344002910	acetyl-CoA carboxylase, biotin carboxyl carrier protein; Region: BCCP; TIGR00531
866344002911	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
866344002912	carboxyltransferase (CT) interaction site; other site
866344002913	biotinylation site [posttranslational modification]; other site
866344002914	biotin carboxylase; Validated; Region: PRK08462
866344002915	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
866344002916	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
866344002917	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
866344002918	Methyltransferase domain; Region: Methyltransf_26; pfam13659
866344002919	potential frameshift: common BLAST hit: gi|210135246|ref|YP_002301685.1| type II R-M system restriction endonuclease
866344002920	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
866344002921	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
866344002922	inhibitor-cofactor binding pocket; inhibition site
866344002923	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866344002924	catalytic residue [active]
866344002925	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
866344002926	dimer interface [polypeptide binding]; other site
866344002927	putative radical transfer pathway; other site
866344002928	diiron center [ion binding]; other site
866344002929	tyrosyl radical; other site
866344002930	protein-L-isoaspartate(D-aspartate) O-methyltransferase; Region: pimt; TIGR00080
866344002931	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866344002932	S-adenosylmethionine binding site [chemical binding]; other site
866344002933	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
866344002934	Predicted permeases [General function prediction only]; Region: COG0795
866344002935	tRNA pseudouridine(38-40) synthase; Region: hisT_truA; TIGR00071
866344002936	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
866344002937	dimerization interface 3.5A [polypeptide binding]; other site
866344002938	active site
866344002939	UDP-glucose-4-epimerase GalE; Region: galE; TIGR01179
866344002940	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
866344002941	NAD binding site [chemical binding]; other site
866344002942	homodimer interface [polypeptide binding]; other site
866344002943	active site
866344002944	substrate binding site [chemical binding]; other site
866344002945	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
866344002946	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
866344002947	putative NAD(P) binding site [chemical binding]; other site
866344002948	homodimer interface [polypeptide binding]; other site
866344002949	homotetramer interface [polypeptide binding]; other site
866344002950	active site
866344002951	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866344002952	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866344002953	binding surface
866344002954	TPR motif; other site
866344002955	Sel1-like repeats; Region: SEL1; smart00671
866344002956	Sel1-like repeats; Region: SEL1; smart00671
866344002957	Sel1-like repeats; Region: SEL1; smart00671
866344002958	Entner-Doudoroff aldolase; Region: eda; TIGR01182
866344002959	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
866344002960	active site
866344002961	intersubunit interface [polypeptide binding]; other site
866344002962	catalytic residue [active]
866344002963	phosphogluconate dehydratase; Validated; Region: PRK09054
866344002964	6-phosphogluconate dehydratase; Region: edd; TIGR01196
866344002965	Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Region: Zwf; COG0364
866344002966	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
866344002967	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
866344002968	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
866344002969	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
866344002970	putative active site [active]
866344002971	glucokinase, proteobacterial type; Region: glk; TIGR00749
866344002972	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
866344002973	nucleotide binding site [chemical binding]; other site
866344002974	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
866344002975	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
866344002976	putative NAD(P) binding site [chemical binding]; other site
866344002977	putative substrate binding site [chemical binding]; other site
866344002978	catalytic Zn binding site [ion binding]; other site
866344002979	structural Zn binding site [ion binding]; other site
866344002980	dimer interface [polypeptide binding]; other site
866344002981	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
866344002982	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
866344002983	active site
866344002984	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
866344002985	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
866344002986	active site
866344002987	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344002988	pyruvate flavodoxin oxidoreductase subunit gamma; Validated; Region: PRK05844
866344002989	pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; Provisional; Region: PRK14029
866344002990	pyruvate flavodoxin oxidoreductase subunit delta; Reviewed; Region: porD; PRK09625
866344002991	4Fe-4S binding domain; Region: Fer4; pfam00037
866344002992	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
866344002993	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
866344002994	dimer interface [polypeptide binding]; other site
866344002995	PYR/PP interface [polypeptide binding]; other site
866344002996	TPP binding site [chemical binding]; other site
866344002997	substrate binding site [chemical binding]; other site
866344002998	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
866344002999	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
866344003000	Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea...; Region: TPP_PFOR_porB_like; cd03376
866344003001	TPP-binding site [chemical binding]; other site
866344003002	putative dimer interface [polypeptide binding]; other site
866344003003	adenylosuccinate lyase; Provisional; Region: PRK08470
866344003004	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
866344003005	tetramer interface [polypeptide binding]; other site
866344003006	active site
866344003007	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
866344003008	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344003009	excinuclease ABC subunit B; Provisional; Region: PRK05298
866344003010	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866344003011	ATP binding site [chemical binding]; other site
866344003012	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
866344003013	putative Mg++ binding site [ion binding]; other site
866344003014	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866344003015	nucleotide binding region [chemical binding]; other site
866344003016	ATP-binding site [chemical binding]; other site
866344003017	Ultra-violet resistance protein B; Region: UvrB; pfam12344
866344003018	UvrB/uvrC motif; Region: UVR; pfam02151
866344003019	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866344003020	binding surface
866344003021	TPR motif; other site
866344003022	TPR repeat; Region: TPR_11; pfam13414
866344003023	Sel1-like repeats; Region: SEL1; smart00671
866344003024	Sel1-like repeats; Region: SEL1; smart00671
866344003025	Sel1-like repeats; Region: SEL1; smart00671
866344003026	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
866344003027	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
866344003028	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08471
866344003029	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
866344003030	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
866344003031	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
866344003032	cofactor binding site; other site
866344003033	DNA binding site [nucleotide binding]
866344003034	substrate interaction site [chemical binding]; other site
866344003035	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
866344003036	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
866344003037	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
866344003038	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
866344003039	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
866344003040	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
866344003041	ligand binding site [chemical binding]; other site
866344003042	translocation protein TolB; Provisional; Region: tolB; PRK04043
866344003043	TolB amino-terminal domain; Region: TolB_N; pfam04052
866344003044	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
866344003045	TonB C terminal; Region: TonB_2; pfam13103
866344003046	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
866344003047	TolR protein; Region: tolR; TIGR02801
866344003048	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
866344003049	ATP synthase, F1 epsilon subunit (delta in mitochondria); Region: ATP_synt_epsi; TIGR01216
866344003050	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
866344003051	gamma subunit interface [polypeptide binding]; other site
866344003052	epsilon subunit interface [polypeptide binding]; other site
866344003053	LBP interface [polypeptide binding]; other site
866344003054	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
866344003055	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
866344003056	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
866344003057	alpha subunit interaction interface [polypeptide binding]; other site
866344003058	Walker A motif; other site
866344003059	ATP binding site [chemical binding]; other site
866344003060	Walker B motif; other site
866344003061	inhibitor binding site; inhibition site
866344003062	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
866344003063	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
866344003064	core domain interface [polypeptide binding]; other site
866344003065	delta subunit interface [polypeptide binding]; other site
866344003066	epsilon subunit interface [polypeptide binding]; other site
866344003067	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
866344003068	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
866344003069	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
866344003070	beta subunit interaction interface [polypeptide binding]; other site
866344003071	Walker A motif; other site
866344003072	ATP binding site [chemical binding]; other site
866344003073	Walker B motif; other site
866344003074	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
866344003075	F0F1 ATP synthase subunit delta; Provisional; Region: PRK13431
866344003076	F0F1 ATP synthase subunit B; Validated; Region: PRK08475
866344003077	F0F1 ATP synthase subunit B'; Validated; Region: PRK08476
866344003078	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
866344003079	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
866344003080	ParB-like nuclease domain; Region: ParB; smart00470
866344003081	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
866344003082	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
866344003083	P-loop; other site
866344003084	Magnesium ion binding site [ion binding]; other site
866344003085	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
866344003086	Magnesium ion binding site [ion binding]; other site
866344003087	biotin--protein ligase; Provisional; Region: PRK08477
866344003088	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
866344003089	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
866344003090	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
866344003091	putative active site [active]
866344003092	substrate binding site [chemical binding]; other site
866344003093	putative cosubstrate binding site; other site
866344003094	catalytic site [active]
866344003095	Formyl transferase, C-terminal domain; Region: Formyl_trans_C; pfam02911
866344003096	PHP-associated; Region: PHP_C; pfam13263
866344003097	AAA domain; Region: AAA_23; pfam13476
866344003098	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866344003099	Walker A/P-loop; other site
866344003100	ATP binding site [chemical binding]; other site
866344003101	AAA domain; Region: AAA_21; pfam13304
866344003102	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
866344003103	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
866344003104	Uncharacterized conserved protein [Function unknown]; Region: COG1432
866344003105	LabA_like proteins; Region: LabA_like; cd06167
866344003106	putative metal binding site [ion binding]; other site
866344003107	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
866344003108	tRNA (Guanine-1)-methyltransferase; Region: tRNA_m1G_MT; cl00407
866344003109	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK14593
866344003110	RimM N-terminal domain; Region: RimM; pfam01782
866344003111	PRC-barrel domain; Region: PRC; pfam05239
866344003112	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
866344003113	KH domain; Region: KH_4; pfam13083
866344003114	G-X-X-G motif; other site
866344003115	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
866344003116	signal recognition particle protein; Provisional; Region: PRK10867
866344003117	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
866344003118	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
866344003119	P loop; other site
866344003120	GTP binding site [chemical binding]; other site
866344003121	Signal peptide binding domain; Region: SRP_SPB; pfam02978
866344003122	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
866344003123	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
866344003124	active site
866344003125	HIGH motif; other site
866344003126	nucleotide binding site [chemical binding]; other site
866344003127	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
866344003128	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
866344003129	active site
866344003130	KMSKS motif; other site
866344003131	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
866344003132	anticodon binding site; other site
866344003133	flagellar assembly protein FliW; Provisional; Region: PRK13283
866344003134	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
866344003135	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
866344003136	active site
866344003137	homodimer interface [polypeptide binding]; other site
866344003138	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344003139	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344003140	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
866344003141	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
866344003142	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
866344003143	Fic/DOC family; Region: Fic; cl00960
866344003144	metal-binding heat shock protein; Provisional; Region: PRK00016
866344003145	flavodoxin FldA; Validated; Region: PRK09267
866344003146	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
866344003147	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
866344003148	Uncharacterized protein, possibly involved in nitrogen fixation [Inorganic ion transport and metabolism]; Region: FixS; COG3197
866344003149	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
866344003150	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
866344003151	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866344003152	Major Facilitator Superfamily; Region: MFS_1; pfam07690
866344003153	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
866344003154	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
866344003155	active site
866344003156	dimer interface [polypeptide binding]; other site
866344003157	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
866344003158	dimer interface [polypeptide binding]; other site
866344003159	active site
866344003160	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866344003161	carbon starvation protein A; Provisional; Region: PRK15015
866344003162	Carbon starvation protein CstA; Region: CstA; pfam02554
866344003163	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
866344003164	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
866344003165	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866344003166	dimer interface [polypeptide binding]; other site
866344003167	conserved gate region; other site
866344003168	putative PBP binding loops; other site
866344003169	ABC-ATPase subunit interface; other site
866344003170	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866344003171	dimer interface [polypeptide binding]; other site
866344003172	conserved gate region; other site
866344003173	putative PBP binding loops; other site
866344003174	ABC-ATPase subunit interface; other site
866344003175	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
866344003176	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
866344003177	Walker A/P-loop; other site
866344003178	ATP binding site [chemical binding]; other site
866344003179	Q-loop/lid; other site
866344003180	ABC transporter signature motif; other site
866344003181	Walker B; other site
866344003182	D-loop; other site
866344003183	H-loop/switch region; other site
866344003184	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
866344003185	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866344003186	substrate binding pocket [chemical binding]; other site
866344003187	membrane-bound complex binding site; other site
866344003188	hinge residues; other site
866344003189	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
866344003190	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866344003191	putative substrate translocation pore; other site
866344003192	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
866344003193	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344003194	purine-nucleoside phosphorylase, family 1 (deoD); Region: deoD; TIGR00107
866344003195	phosphopentomutase; Provisional; Region: PRK05362
866344003196	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
866344003197	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
866344003198	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
866344003199	Nucleoside recognition; Region: Gate; pfam07670
866344003200	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
866344003201	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866344003202	Major Facilitator Superfamily; Region: MFS_1; pfam07690
866344003203	putative substrate translocation pore; other site
866344003204	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
866344003205	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
866344003206	Ligand Binding Site [chemical binding]; other site
866344003207	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
866344003208	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
866344003209	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
866344003210	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
866344003211	putative arabinose transporter; Provisional; Region: PRK03545
866344003212	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866344003213	putative substrate translocation pore; other site
866344003214	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
866344003215	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
866344003216	active site
866344003217	zinc binding site [ion binding]; other site
866344003218	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
866344003219	aspartate-semialdehyde dehydrogenase (peptidoglycan organisms); Region: asd_B; TIGR01296
866344003220	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
866344003221	Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: HisS; COG0124
866344003222	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
866344003223	dimer interface [polypeptide binding]; other site
866344003224	motif 1; other site
866344003225	active site
866344003226	motif 2; other site
866344003227	motif 3; other site
866344003228	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
866344003229	anticodon binding site; other site
866344003230	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
866344003231	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
866344003232	putative active site [active]
866344003233	elongation factor G; Reviewed; Region: PRK00007
866344003234	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
866344003235	G1 box; other site
866344003236	putative GEF interaction site [polypeptide binding]; other site
866344003237	GTP/Mg2+ binding site [chemical binding]; other site
866344003238	Switch I region; other site
866344003239	G2 box; other site
866344003240	G3 box; other site
866344003241	Switch II region; other site
866344003242	G4 box; other site
866344003243	G5 box; other site
866344003244	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
866344003245	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
866344003246	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
866344003247	30S ribosomal protein S7; Validated; Region: PRK05302
866344003248	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
866344003249	S17 interaction site [polypeptide binding]; other site
866344003250	S8 interaction site; other site
866344003251	16S rRNA interaction site [nucleotide binding]; other site
866344003252	streptomycin interaction site [chemical binding]; other site
866344003253	23S rRNA interaction site [nucleotide binding]; other site
866344003254	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
866344003255	bifunctional DNA-directed RNA polymerase subunit beta/beta'; Reviewed; Region: PRK09603
866344003256	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
866344003257	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
866344003258	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
866344003259	RPB11 interaction site [polypeptide binding]; other site
866344003260	RPB12 interaction site [polypeptide binding]; other site
866344003261	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
866344003262	RPB3 interaction site [polypeptide binding]; other site
866344003263	RPB1 interaction site [polypeptide binding]; other site
866344003264	RPB11 interaction site [polypeptide binding]; other site
866344003265	RPB10 interaction site [polypeptide binding]; other site
866344003266	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
866344003267	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
866344003268	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
866344003269	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
866344003270	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
866344003271	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
866344003272	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
866344003273	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
866344003274	DNA binding site [nucleotide binding]
866344003275	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
866344003276	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
866344003277	core dimer interface [polypeptide binding]; other site
866344003278	peripheral dimer interface [polypeptide binding]; other site
866344003279	L10 interface [polypeptide binding]; other site
866344003280	L11 interface [polypeptide binding]; other site
866344003281	putative EF-Tu interaction site [polypeptide binding]; other site
866344003282	putative EF-G interaction site [polypeptide binding]; other site
866344003283	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
866344003284	23S rRNA interface [nucleotide binding]; other site
866344003285	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
866344003286	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
866344003287	mRNA/rRNA interface [nucleotide binding]; other site
866344003288	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
866344003289	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
866344003290	23S rRNA interface [nucleotide binding]; other site
866344003291	L7/L12 interface [polypeptide binding]; other site
866344003292	putative thiostrepton binding site; other site
866344003293	L25 interface [polypeptide binding]; other site
866344003294	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
866344003295	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
866344003296	putative homodimer interface [polypeptide binding]; other site
866344003297	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
866344003298	heterodimer interface [polypeptide binding]; other site
866344003299	homodimer interface [polypeptide binding]; other site
866344003300	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; cl00481
866344003301	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
866344003302	elongation factor Tu; Reviewed; Region: PRK00049
866344003303	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
866344003304	G1 box; other site
866344003305	GEF interaction site [polypeptide binding]; other site
866344003306	GTP/Mg2+ binding site [chemical binding]; other site
866344003307	Switch I region; other site
866344003308	G2 box; other site
866344003309	G3 box; other site
866344003310	Switch II region; other site
866344003311	G4 box; other site
866344003312	G5 box; other site
866344003313	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
866344003314	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
866344003315	Antibiotic Binding Site [chemical binding]; other site
866344003316	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
866344003317	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
866344003318	Walker A/P-loop; other site
866344003319	ATP binding site [chemical binding]; other site
866344003320	Q-loop/lid; other site
866344003321	ABC transporter signature motif; other site
866344003322	Walker B; other site
866344003323	D-loop; other site
866344003324	H-loop/switch region; other site
866344003325	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
866344003326	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
866344003327	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
866344003328	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; pfam02086
866344003329	serine O-acetyltransferase; Region: cysE; TIGR01172
866344003330	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
866344003331	trimer interface [polypeptide binding]; other site
866344003332	active site
866344003333	substrate binding site [chemical binding]; other site
866344003334	CoA binding site [chemical binding]; other site
866344003335	F0F1 ATP synthase subunit C; Validated; Region: PRK08482
866344003336	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
866344003337	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
866344003338	oligomer interface [polypeptide binding]; other site
866344003339	RNA binding site [nucleotide binding]; other site
866344003340	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
866344003341	oligomer interface [polypeptide binding]; other site
866344003342	RNA binding site [nucleotide binding]; other site
866344003343	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
866344003344	putative nucleic acid binding region [nucleotide binding]; other site
866344003345	G-X-X-G motif; other site
866344003346	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
866344003347	RNA binding site [nucleotide binding]; other site
866344003348	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG1926
866344003349	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
866344003350	Organic solvent tolerance protein; Region: OstA_C; pfam04453
866344003351	Predicted membrane protein/domain [Function unknown]; Region: COG1714
866344003352	phosphoribosylamine--glycine ligase; Region: purD; TIGR00877
866344003353	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
866344003354	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
866344003355	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
866344003356	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
866344003357	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
866344003358	Walker A/P-loop; other site
866344003359	ATP binding site [chemical binding]; other site
866344003360	Q-loop/lid; other site
866344003361	ABC transporter signature motif; other site
866344003362	Walker B; other site
866344003363	D-loop; other site
866344003364	H-loop/switch region; other site
866344003365	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
866344003366	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
866344003367	catalytic residue [active]
866344003368	putative FPP diphosphate  binding site; other site
866344003369	putative FPP binding hydrophobic cleft; other site
866344003370	dimer interface [polypeptide binding]; other site
866344003371	putative IPP diphosphate binding site; other site
866344003372	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
866344003373	FAD binding domain; Region: FAD_binding_4; pfam01565
866344003374	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
866344003375	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
866344003376	active site residue [active]
866344003377	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
866344003378	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
866344003379	active site
866344003380	camphor resistance protein CrcB; Provisional; Region: PRK14204
866344003381	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
866344003382	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866344003383	FeS/SAM binding site; other site
866344003384	HemN C-terminal domain; Region: HemN_C; pfam06969
866344003385	Cytochrome c553 [Energy production and conversion]; Region: COG2863
866344003386	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
866344003387	putative active site [active]
866344003388	Ap4A binding site [chemical binding]; other site
866344003389	nudix motif; other site
866344003390	putative metal binding site [ion binding]; other site
866344003391	aspartate kinase; Reviewed; Region: PRK06635
866344003392	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
866344003393	putative nucleotide binding site [chemical binding]; other site
866344003394	putative catalytic residues [active]
866344003395	putative Mg ion binding site [ion binding]; other site
866344003396	putative aspartate binding site [chemical binding]; other site
866344003397	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
866344003398	putative allosteric regulatory site; other site
866344003399	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
866344003400	putative allosteric regulatory residue; other site
866344003401	DNA replication regulator; Region: HobA; pfam12163
866344003402	DNA polymerase III subunit delta'; Validated; Region: PRK08485
866344003403	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
866344003404	dihydropteroate synthase; Region: DHPS; TIGR01496
866344003405	substrate binding pocket [chemical binding]; other site
866344003406	dimer interface [polypeptide binding]; other site
866344003407	inhibitor binding site; inhibition site
866344003408	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
866344003409	EamA-like transporter family; Region: EamA; pfam00892
866344003410	EamA-like transporter family; Region: EamA; cl17759
866344003411	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
866344003412	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2952
866344003413	Carbamoylphosphate synthase small subunit [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarA; COG0505
866344003414	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
866344003415	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
866344003416	catalytic site [active]
866344003417	subunit interface [polypeptide binding]; other site
866344003418	formamidase; Provisional; Region: amiF; PRK13287
866344003419	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
866344003420	multimer interface [polypeptide binding]; other site
866344003421	active site
866344003422	catalytic triad [active]
866344003423	dimer interface [polypeptide binding]; other site
866344003424	Maf-like protein; Region: Maf; pfam02545
866344003425	Maf-like protein; Reviewed; Region: PRK04056
866344003426	putative active site [active]
866344003427	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
866344003428	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
866344003429	motif 1; other site
866344003430	active site
866344003431	motif 2; other site
866344003432	motif 3; other site
866344003433	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
866344003434	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
866344003435	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344003436	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
866344003437	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
866344003438	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
866344003439	dimer interface [polypeptide binding]; other site
866344003440	ssDNA binding site [nucleotide binding]; other site
866344003441	tetramer (dimer of dimers) interface [polypeptide binding]; other site
866344003442	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
866344003443	DNA polymerase III subunit delta; Validated; Region: PRK08487
866344003444	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
866344003445	Exoribonuclease R [Transcription]; Region: VacB; COG0557
866344003446	RNB domain; Region: RNB; pfam00773
866344003447	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
866344003448	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
866344003449	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
866344003450	shikimate binding site; other site
866344003451	NAD(P) binding site [chemical binding]; other site
866344003452	Bacterial SH3 domain; Region: SH3_3; pfam08239
866344003453	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
866344003454	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866344003455	dimer interface [polypeptide binding]; other site
866344003456	conserved gate region; other site
866344003457	putative PBP binding loops; other site
866344003458	ABC-ATPase subunit interface; other site
866344003459	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
866344003460	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
866344003461	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
866344003462	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
866344003463	active site
866344003464	HIGH motif; other site
866344003465	dimer interface [polypeptide binding]; other site
866344003466	KMSKS motif; other site
866344003467	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
866344003468	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866344003469	S-adenosylmethionine binding site [chemical binding]; other site
866344003470	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
866344003471	ribosome recycling factor; Reviewed; Region: frr; PRK00083
866344003472	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
866344003473	hinge region; other site
866344003474	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866344003475	active site
866344003476	RDD family; Region: RDD; pfam06271
866344003477	potential frameshift: common BLAST hit: gi|308185007|ref|YP_003929140.1| NAD-dependent deacetylase
866344003478	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
866344003479	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
866344003480	NADH dehydrogenase subunit A; Validated; Region: PRK08489
866344003481	NADH dehydrogenase subunit B; Validated; Region: PRK06411
866344003482	NADH dehydrogenase subunit C; Provisional; Region: PRK08491
866344003483	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
866344003484	NADH dehydrogenase subunit D; Validated; Region: PRK06075
866344003485	NADH dehydrogenase I, D subunit; Region: NuoD; TIGR01962
866344003486	NADH dehydrogenase subunit G; Validated; Region: PRK08493
866344003487	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
866344003488	catalytic loop [active]
866344003489	iron binding site [ion binding]; other site
866344003490	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
866344003491	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866344003492	molybdopterin cofactor binding site; other site
866344003493	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
866344003494	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
866344003495	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
866344003496	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
866344003497	4Fe-4S binding domain; Region: Fer4; cl02805
866344003498	4Fe-4S binding domain; Region: Fer4; pfam00037
866344003499	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
866344003500	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
866344003501	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
866344003502	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
866344003503	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
866344003504	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
866344003505	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
866344003506	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
866344003507	proton-translocating NADH-quinone oxidoreductase, chain N; Region: NDH_I_N; TIGR01770
866344003508	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
866344003509	Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats [Function unknown]; Region: COG4700
866344003510	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
866344003511	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
866344003512	active site
866344003513	substrate binding site [chemical binding]; other site
866344003514	metal binding site [ion binding]; metal-binding site
866344003515	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
866344003516	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
866344003517	substrate binding site [chemical binding]; other site
866344003518	active site
866344003519	catalytic residues [active]
866344003520	heterodimer interface [polypeptide binding]; other site
866344003521	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
866344003522	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
866344003523	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866344003524	catalytic residue [active]
866344003525	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
866344003526	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
866344003527	active site
866344003528	ribulose/triose binding site [chemical binding]; other site
866344003529	phosphate binding site [ion binding]; other site
866344003530	substrate (anthranilate) binding pocket [chemical binding]; other site
866344003531	product (indole) binding pocket [chemical binding]; other site
866344003532	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
866344003533	active site
866344003534	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
866344003535	anthranilate phosphoribosyltransferase; Region: trpD; TIGR01245
866344003536	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
866344003537	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
866344003538	Glutamine amidotransferase class-I; Region: GATase; pfam00117
866344003539	glutamine binding [chemical binding]; other site
866344003540	catalytic triad [active]
866344003541	anthranilate synthase component I, proteobacterial subset; Region: trpE_proteo; TIGR00565
866344003542	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
866344003543	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
866344003544	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
866344003545	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
866344003546	putative active site [active]
866344003547	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866344003548	active site
866344003549	motif I; other site
866344003550	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
866344003551	motif II; other site
866344003552	Uncharacterized conserved protein [Function unknown]; Region: COG2353
866344003553	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
866344003554	Nicotinamide mononucleotide transporter [Coenzyme metabolism]; Region: PnuC; COG3201
866344003555	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
866344003556	Thiamine pyrophosphokinase; Region: TPK; cd07995
866344003557	active site
866344003558	dimerization interface [polypeptide binding]; other site
866344003559	thiamine binding site [chemical binding]; other site
866344003560	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
866344003561	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
866344003562	alphaNTD homodimer interface [polypeptide binding]; other site
866344003563	DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type; Region: rpoA; TIGR02027
866344003564	alphaNTD - beta interaction site [polypeptide binding]; other site
866344003565	alphaNTD - beta' interaction site [polypeptide binding]; other site
866344003566	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
866344003567	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
866344003568	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
866344003569	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866344003570	RNA binding surface [nucleotide binding]; other site
866344003571	30S ribosomal protein S11; Validated; Region: PRK05309
866344003572	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
866344003573	30S ribosomal protein S13; Region: bact_S13; TIGR03631
866344003574	Ribosomal protein L36; Region: Ribosomal_L36; cl00380
866344003575	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
866344003576	rRNA binding site [nucleotide binding]; other site
866344003577	predicted 30S ribosome binding site; other site
866344003578	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
866344003579	active site
866344003580	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
866344003581	SecY translocase; Region: SecY; pfam00344
866344003582	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
866344003583	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
866344003584	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
866344003585	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
866344003586	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
866344003587	23S rRNA interface [nucleotide binding]; other site
866344003588	5S rRNA interface [nucleotide binding]; other site
866344003589	L27 interface [polypeptide binding]; other site
866344003590	L5 interface [polypeptide binding]; other site
866344003591	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
866344003592	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
866344003593	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
866344003594	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
866344003595	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
866344003596	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
866344003597	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
866344003598	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
866344003599	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
866344003600	RNA binding site [nucleotide binding]; other site
866344003601	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
866344003602	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
866344003603	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
866344003604	putative translocon interaction site; other site
866344003605	23S rRNA interface [nucleotide binding]; other site
866344003606	signal recognition particle (SRP54) interaction site; other site
866344003607	L23 interface [polypeptide binding]; other site
866344003608	trigger factor interaction site; other site
866344003609	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
866344003610	23S rRNA interface [nucleotide binding]; other site
866344003611	5S rRNA interface [nucleotide binding]; other site
866344003612	putative antibiotic binding site [chemical binding]; other site
866344003613	L25 interface [polypeptide binding]; other site
866344003614	L27 interface [polypeptide binding]; other site
866344003615	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
866344003616	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
866344003617	G-X-X-G motif; other site
866344003618	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
866344003619	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
866344003620	putative translocon binding site; other site
866344003621	protein-rRNA interface [nucleotide binding]; other site
866344003622	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
866344003623	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
866344003624	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
866344003625	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
866344003626	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
866344003627	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
866344003628	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
866344003629	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
866344003630	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
866344003631	AAA domain; Region: AAA_14; pfam13173
866344003632	Helix-turn-helix domain; Region: HTH_36; pfam13730
866344003633	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
866344003634	RNA/DNA hybrid binding site [nucleotide binding]; other site
866344003635	active site
866344003636	fumarate hydratase; Reviewed; Region: fumC; PRK00485
866344003637	Class II fumarases; Region: Fumarase_classII; cd01362
866344003638	active site
866344003639	tetramer interface [polypeptide binding]; other site
866344003640	YtkA-like; Region: YtkA; pfam13115
866344003641	Outer membrane efflux protein; Region: OEP; pfam02321
866344003642	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
866344003643	HlyD family secretion protein; Region: HlyD_3; pfam13437
866344003644	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
866344003645	Predicted branched-chain amino acid permeases (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlD; COG1687
866344003646	AzlC protein; Region: AzlC; cl00570
866344003647	chaperone protein DnaJ; Provisional; Region: PRK14288
866344003648	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
866344003649	HSP70 interaction site [polypeptide binding]; other site
866344003650	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
866344003651	substrate binding site [polypeptide binding]; other site
866344003652	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
866344003653	Zn binding sites [ion binding]; other site
866344003654	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
866344003655	dimer interface [polypeptide binding]; other site
866344003656	Uncharacterized conserved protein [Function unknown]; Region: COG1432
866344003657	LabA_like proteins; Region: LabA_like; cd06167
866344003658	putative metal binding site [ion binding]; other site
866344003659	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
866344003660	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
866344003661	Ligand Binding Site [chemical binding]; other site
866344003662	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
866344003663	HSP70 interaction site [polypeptide binding]; other site
866344003664	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
866344003665	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
866344003666	active site
866344003667	(T/H)XGH motif; other site
866344003668	nickel responsive regulator; Provisional; Region: PRK00630
866344003669	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
866344003670	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
866344003671	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
866344003672	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
866344003673	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
866344003674	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
866344003675	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
866344003676	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344003677	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866344003678	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957
866344003679	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
866344003680	Acylphosphatase; Region: Acylphosphatase; pfam00708
866344003681	[NiFe] hydrogenase maturation protein HypF; Region: hypF; TIGR00143
866344003682	HypF finger; Region: zf-HYPF; pfam07503
866344003683	HypF finger; Region: zf-HYPF; pfam07503
866344003684	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
866344003685	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
866344003686	dimerization interface [polypeptide binding]; other site
866344003687	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
866344003688	ATP binding site [chemical binding]; other site
866344003689	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
866344003690	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
866344003691	NADP binding site [chemical binding]; other site
866344003692	active site
866344003693	putative substrate binding site [chemical binding]; other site
866344003694	GDP-mannose 4,6-dehydratase; Region: gmd; TIGR01472
866344003695	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
866344003696	NADP-binding site; other site
866344003697	homotetramer interface [polypeptide binding]; other site
866344003698	substrate binding site [chemical binding]; other site
866344003699	homodimer interface [polypeptide binding]; other site
866344003700	active site
866344003701	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
866344003702	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
866344003703	Substrate binding site; other site
866344003704	Cupin domain; Region: Cupin_2; cl17218
866344003705	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
866344003706	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
866344003707	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
866344003708	VirB7 interaction site; other site
866344003709	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
866344003710	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
866344003711	PDZ domain; Region: PDZ_2; pfam13180
866344003712	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
866344003713	hypothetical protein; Provisional; Region: PRK03762
866344003714	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
866344003715	tetramerization interface [polypeptide binding]; other site
866344003716	active site
866344003717	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
866344003718	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344003719	Walker A motif; other site
866344003720	ATP binding site [chemical binding]; other site
866344003721	Walker B motif; other site
866344003722	arginine finger; other site
866344003723	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344003724	Walker A motif; other site
866344003725	ATP binding site [chemical binding]; other site
866344003726	Walker B motif; other site
866344003727	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
866344003728	Uncharacterized conserved protein [Function unknown]; Region: COG2127
866344003729	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
866344003730	Ligand Binding Site [chemical binding]; other site
866344003731	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
866344003732	AAA domain; Region: AAA_26; pfam13500
866344003733	Protein of unknown function (DUF1523); Region: DUF1523; pfam07509
866344003734	isocitrate dehydrogenase; Validated; Region: PRK07362
866344003735	isocitrate dehydrogenase; Reviewed; Region: PRK07006
866344003736	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
866344003737	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
866344003738	dimer interface [polypeptide binding]; other site
866344003739	active site
866344003740	citrylCoA binding site [chemical binding]; other site
866344003741	NADH binding [chemical binding]; other site
866344003742	cationic pore residues; other site
866344003743	oxalacetate/citrate binding site [chemical binding]; other site
866344003744	coenzyme A binding site [chemical binding]; other site
866344003745	catalytic triad [active]
866344003746	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cl00089
866344003747	Type III restriction/modification enzyme methylation subunit; Region: TypeIII_RM_meth; pfam12564
866344003748	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
866344003749	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344003750	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344003751	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3421
866344003752	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
866344003753	ATP binding site [chemical binding]; other site
866344003754	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
866344003755	putative Mg++ binding site [ion binding]; other site
866344003756	biotin synthase; Provisional; Region: PRK08508
866344003757	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866344003758	FeS/SAM binding site; other site
866344003759	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
866344003760	YihY family inner membrane protein; Region: yihY_not_rbn; TIGR00765
866344003761	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866344003762	Protein of unknown function DUF262; Region: DUF262; pfam03235
866344003763	Protein of unknown function DUF262; Region: DUF262; pfam03235
866344003764	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866344003765	Single-stranded DNA-specific exonuclease [DNA replication, recombination, and repair]; Region: RecJ; COG0608
866344003766	DHH family; Region: DHH; pfam01368
866344003767	Single-stranded DNA-specific exonuclease [DNA replication, recombination, and repair]; Region: RecJ; COG0608
866344003768	Pleckstrin homology-like domain; Region: PH-like; cl17171
866344003769	Peptidase family M23; Region: Peptidase_M23; pfam01551
866344003770	7-cyano-7-deazaguanine reductase; Region: QueF-II; TIGR03139
866344003771	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
866344003772	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
866344003773	tRNA dimethylallyltransferase; Region: miaA; TIGR00174
866344003774	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
866344003775	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
866344003776	Ligand binding site; other site
866344003777	metal-binding site
866344003778	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
866344003779	Sulfatase; Region: Sulfatase; cl17466
866344003780	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
866344003781	Sulfatase; Region: Sulfatase; cl17466
866344003782	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13904
866344003783	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
866344003784	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
866344003785	flagellum-specific ATP synthase; Validated; Region: fliI; PRK08472
866344003786	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
866344003787	Walker A motif/ATP binding site; other site
866344003788	Walker B motif; other site
866344003789	Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis [Cell motility and secretion / Intracellular trafficking and secretion]; Region: VirB11; COG0630
866344003790	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
866344003791	ATP binding site [chemical binding]; other site
866344003792	Walker A motif; other site
866344003793	hexamer interface [polypeptide binding]; other site
866344003794	Walker B motif; other site
866344003795	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
866344003796	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
866344003797	active site
866344003798	HIGH motif; other site
866344003799	nucleotide binding site [chemical binding]; other site
866344003800	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
866344003801	active site
866344003802	KMSKS motif; other site
866344003803	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
866344003804	tRNA binding surface [nucleotide binding]; other site
866344003805	anticodon binding site; other site
866344003806	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
866344003807	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866344003808	RNA binding surface [nucleotide binding]; other site
866344003809	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14462
866344003810	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866344003811	FeS/SAM binding site; other site
866344003812	KpsF/GutQ family protein; Region: kpsF; TIGR00393
866344003813	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
866344003814	putative active site [active]
866344003815	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
866344003816	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
866344003817	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
866344003818	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
866344003819	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
866344003820	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866344003821	S-adenosylmethionine binding site [chemical binding]; other site
866344003822	formyltetrahydrofolate deformylase; Region: PurU; TIGR00655
866344003823	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
866344003824	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
866344003825	active site
866344003826	substrate binding site [chemical binding]; other site
866344003827	cosubstrate binding site; other site
866344003828	catalytic site [active]
866344003829	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
866344003830	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
866344003831	tandem repeat interface [polypeptide binding]; other site
866344003832	oligomer interface [polypeptide binding]; other site
866344003833	active site residues [active]
866344003834	TIR domain; Region: TIR_2; pfam13676
866344003835	rod shape-determining protein MreC; Provisional; Region: PRK13922
866344003836	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
866344003837	active site
866344003838	carbon storage regulator; Provisional; Region: PRK00568
866344003839	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK04181
866344003840	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
866344003841	SmpB-tmRNA interface; other site
866344003842	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
866344003843	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
866344003844	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
866344003845	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
866344003846	ribonuclease P protein component, eubacterial; Region: rnpA; TIGR00188
866344003847	hypothetical protein; Provisional; Region: PRK14374
866344003848	membrane protein insertase; Provisional; Region: PRK01318
866344003849	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
866344003850	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
866344003851	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
866344003852	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
866344003853	tRNA modification GTPase TrmE; Region: mnmE_trmE_thdF; TIGR00450
866344003854	trmE is a tRNA modification GTPase; Region: trmE; cd04164
866344003855	G1 box; other site
866344003856	GTP/Mg2+ binding site [chemical binding]; other site
866344003857	Switch I region; other site
866344003858	G2 box; other site
866344003859	Switch II region; other site
866344003860	G3 box; other site
866344003861	G4 box; other site
866344003862	G5 box; other site
866344003863	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
866344003864	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344003865	LPP20 lipoprotein; Region: LPP20; pfam02169
866344003866	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
866344003867	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
866344003868	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
866344003869	catalytic residues [active]
866344003870	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
866344003871	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866344003872	RNA binding surface [nucleotide binding]; other site
866344003873	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
866344003874	active site
866344003875	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
866344003876	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
866344003877	active site
866344003878	PHP Thumb interface [polypeptide binding]; other site
866344003879	metal binding site [ion binding]; metal-binding site
866344003880	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
866344003881	generic binding surface I; other site
866344003882	generic binding surface II; other site
866344003883	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
866344003884	Heat shock protein [Posttranslational modification, protein turnover, chaperones]; Region: HslJ; COG3187
866344003885	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
866344003886	mce related protein; Region: MCE; pfam02470
866344003887	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
866344003888	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
866344003889	Walker A/P-loop; other site
866344003890	ATP binding site [chemical binding]; other site
866344003891	Q-loop/lid; other site
866344003892	ABC transporter signature motif; other site
866344003893	Walker B; other site
866344003894	D-loop; other site
866344003895	H-loop/switch region; other site
866344003896	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
866344003897	conserved hypothetical integral membrane protein; Region: TIGR00056
866344003898	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344003899	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
866344003900	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
866344003901	homodimer interface [polypeptide binding]; other site
866344003902	substrate-cofactor binding pocket; other site
866344003903	catalytic residue [active]
866344003904	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344003905	DNA polymerase I; Region: pola; TIGR00593
866344003906	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
866344003907	active site
866344003908	metal binding site 1 [ion binding]; metal-binding site
866344003909	putative 5' ssDNA interaction site; other site
866344003910	metal binding site 3; metal-binding site
866344003911	metal binding site 2 [ion binding]; metal-binding site
866344003912	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
866344003913	putative DNA binding site [nucleotide binding]; other site
866344003914	putative metal binding site [ion binding]; other site
866344003915	3'-5' exonuclease; Region: 35EXOc; smart00474
866344003916	active site
866344003917	substrate binding site [chemical binding]; other site
866344003918	catalytic site [active]
866344003919	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
866344003920	active site
866344003921	DNA binding site [nucleotide binding]
866344003922	catalytic site [active]
866344003923	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866344003924	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
866344003925	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
866344003926	thymidylate kinase; Validated; Region: tmk; PRK00698
866344003927	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
866344003928	TMP-binding site; other site
866344003929	ATP-binding site [chemical binding]; other site
866344003930	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
866344003931	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
866344003932	active site
866344003933	(T/H)XGH motif; other site
866344003934	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
866344003935	Flavoprotein; Region: Flavoprotein; pfam02441
866344003936	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK08515
866344003937	flagella basal body P-ring formation protein FlgA; Region: flgA_cterm; TIGR03170
866344003938	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
866344003939	Part of AAA domain; Region: AAA_19; pfam13245
866344003940	Family description; Region: UvrD_C_2; pfam13538
866344003941	TPR repeat; Region: TPR_11; pfam13414
866344003942	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866344003943	TPR motif; other site
866344003944	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866344003945	binding surface
866344003946	TPR motif; other site
866344003947	seryl-tRNA synthetase; Provisional; Region: PRK05431
866344003948	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
866344003949	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
866344003950	dimer interface [polypeptide binding]; other site
866344003951	active site
866344003952	motif 1; other site
866344003953	motif 2; other site
866344003954	motif 3; other site
866344003955	Predicted amidohydrolase [General function prediction only]; Region: COG0388
866344003956	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
866344003957	active site
866344003958	catalytic triad [active]
866344003959	dimer interface [polypeptide binding]; other site
866344003960	Exonuclease VII small subunit; Region: Exonuc_VII_S; cl00750
866344003961	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
866344003962	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866344003963	S-adenosylmethionine binding site [chemical binding]; other site
866344003964	Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863
866344003965	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
866344003966	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
866344003967	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
866344003968	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
866344003969	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
866344003970	ABC-2 type transporter; Region: ABC2_membrane; cl17235
866344003971	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
866344003972	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866344003973	HlyD family secretion protein; Region: HlyD_3; pfam13437
866344003974	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
866344003975	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
866344003976	Domain of unknown function DUF21; Region: DUF21; pfam01595
866344003977	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
866344003978	Transporter associated domain; Region: CorC_HlyC; smart01091
866344003979	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
866344003980	Phosphate transporter family; Region: PHO4; pfam01384
866344003981	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
866344003982	UDP-N-acetylmuramyl-tripeptide synthetase; Region: murE; TIGR01085
866344003983	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866344003984	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866344003985	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
866344003986	putative active site [active]
866344003987	transaldolase; Provisional; Region: PRK03903
866344003988	catalytic residue [active]
866344003989	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
866344003990	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
866344003991	5S rRNA interface [nucleotide binding]; other site
866344003992	CTC domain interface [polypeptide binding]; other site
866344003993	L16 interface [polypeptide binding]; other site
866344003994	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
866344003995	putative active site [active]
866344003996	catalytic residue [active]
866344003997	Predicted permeases [General function prediction only]; Region: COG0795
866344003998	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
866344003999	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
866344004000	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
866344004001	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
866344004002	potential frameshift: common BLAST hit: gi|298735529|ref|YP_003728050.1| putative endonuclease
866344004003	potential frameshift: common BLAST hit: gi|308185271|ref|YP_003929404.1| restriction endonuclease
866344004004	AlwI restriction endonuclease; Region: RE_AlwI; pfam09491
866344004005	AlwI restriction endonuclease; Region: RE_AlwI; pfam09491
866344004006	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344004007	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3399
866344004008	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
866344004009	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
866344004010	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
866344004011	metal-binding site [ion binding]
866344004012	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
866344004013	Soluble P-type ATPase [General function prediction only]; Region: COG4087
866344004014	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
866344004015	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866344004016	S-adenosylmethionine binding site [chemical binding]; other site
866344004017	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
866344004018	catalytic motif [active]
866344004019	Zn binding site [ion binding]; other site
866344004020	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
866344004021	RibD C-terminal domain; Region: RibD_C; cl17279
866344004022	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
866344004023	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
866344004024	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
866344004025	NAD(P) binding pocket [chemical binding]; other site
866344004026	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
866344004027	4Fe-4S binding domain; Region: Fer4_5; pfam12801
866344004028	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
866344004029	acyl-phosphate glycerol 3-phosphate acyltransferase; Region: TIGR00023
866344004030	FolB domain; Region: folB_dom; TIGR00526
866344004031	active site
866344004032	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
866344004033	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866344004034	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866344004035	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
866344004036	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
866344004037	transcription elongation factor NusA; Provisional; Region: nusA; PRK12328
866344004038	NusA N-terminal domain; Region: NusA_N; pfam08529
866344004039	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
866344004040	RNA binding site [nucleotide binding]; other site
866344004041	homodimer interface [polypeptide binding]; other site
866344004042	NusA-like KH domain; Region: KH_5; pfam13184
866344004043	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
866344004044	G-X-X-G motif; other site
866344004045	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
866344004046	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
866344004047	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
866344004048	Restriction endonuclease [Defense mechanisms]; Region: COG3587
866344004049	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866344004050	ATP binding site [chemical binding]; other site
866344004051	putative Mg++ binding site [ion binding]; other site
866344004052	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
866344004053	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344004054	DNA methylase; Region: N6_N4_Mtase; pfam01555
866344004055	ATP-dependent DNA helicase RecG; Region: recG; TIGR00643
866344004056	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
866344004057	ssDNA binding site; other site
866344004058	generic binding surface II; other site
866344004059	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866344004060	ATP binding site [chemical binding]; other site
866344004061	putative Mg++ binding site [ion binding]; other site
866344004062	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866344004063	nucleotide binding region [chemical binding]; other site
866344004064	ATP-binding site [chemical binding]; other site
866344004065	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344004066	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
866344004067	active site
866344004068	putative catalytic site [active]
866344004069	DNA binding site [nucleotide binding]
866344004070	putative phosphate binding site [ion binding]; other site
866344004071	metal binding site A [ion binding]; metal-binding site
866344004072	AP binding site [nucleotide binding]; other site
866344004073	metal binding site B [ion binding]; metal-binding site
866344004074	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
866344004075	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866344004076	Walker A motif; other site
866344004077	ATP binding site [chemical binding]; other site
866344004078	Walker B motif; other site
866344004079	arginine finger; other site
866344004080	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
866344004081	DnaA box-binding interface [nucleotide binding]; other site
866344004082	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
866344004083	Protein of unknown function (DUF2443); Region: DUF2443; pfam10398
866344004084	glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Region: glmS; TIGR01135
866344004085	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
866344004086	glutaminase active site [active]
866344004087	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
866344004088	dimer interface [polypeptide binding]; other site
866344004089	active site
866344004090	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
866344004091	dimer interface [polypeptide binding]; other site
866344004092	active site
866344004093	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
866344004094	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866344004095	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
866344004096	Abi-like protein; Region: Abi_2; cl01988
866344004097	HsdM N-terminal domain; Region: HsdM_N; pfam12161
866344004098	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
866344004099	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
866344004100	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
866344004101	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866344004102	ATP binding site [chemical binding]; other site
866344004103	putative Mg++ binding site [ion binding]; other site
866344004104	Protein of unknown function DUF45; Region: DUF45; pfam01863
866344004105	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
866344004106	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
866344004107	N-terminal plug; other site
866344004108	ligand-binding site [chemical binding]; other site
866344004109	Arginase family; Region: Arginase; cd09989
866344004110	active site
866344004111	Mn binding site [ion binding]; other site
866344004112	oligomer interface [polypeptide binding]; other site
866344004113	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
866344004114	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
866344004115	hexamer interface [polypeptide binding]; other site
866344004116	ligand binding site [chemical binding]; other site
866344004117	putative active site [active]
866344004118	NAD(P) binding site [chemical binding]; other site
866344004119	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866344004120	Protein of unknown function DUF262; Region: DUF262; pfam03235
866344004121	Protein of unknown function DUF262; Region: DUF262; pfam03235
866344004122	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866344004123	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866344004124	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866344004125	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
866344004126	ATP-NAD kinase; Region: NAD_kinase; pfam01513
866344004127	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
866344004128	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866344004129	Walker A/P-loop; other site
866344004130	ATP binding site [chemical binding]; other site
866344004131	Q-loop/lid; other site
866344004132	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
866344004133	ABC transporter signature motif; other site
866344004134	Walker B; other site
866344004135	D-loop; other site
866344004136	H-loop/switch region; other site
866344004137	Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293
866344004138	Domain of unknown function (DUF814); Region: DUF814; pfam05670
866344004139	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866344004140	DNA polymerase III subunit epsilon; Provisional; Region: PRK08517
866344004141	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
866344004142	active site
866344004143	catalytic site [active]
866344004144	substrate binding site [chemical binding]; other site
866344004145	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
866344004146	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
866344004147	substrate binding site [chemical binding]; other site
866344004148	hexamer interface [polypeptide binding]; other site
866344004149	metal binding site [ion binding]; metal-binding site
866344004150	Fructose-1,6-bisphosphatase [Carbohydrate transport and metabolism]; Region: Fbp; COG0158
866344004151	active site
866344004152	Methyltransferase domain; Region: Methyltransf_26; pfam13659
866344004153	elongation factor Ts; Provisional; Region: tsf; PRK09377
866344004154	UBA/TS-N domain; Region: UBA; pfam00627
866344004155	Elongation factor TS; Region: EF_TS; pfam00889
866344004156	Elongation factor TS; Region: EF_TS; pfam00889
866344004157	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
866344004158	rRNA interaction site [nucleotide binding]; other site
866344004159	S8 interaction site; other site
866344004160	putative laminin-1 binding site; other site
866344004161	putative recombination protein RecB; Provisional; Region: PRK13909
866344004162	Family description; Region: UvrD_C_2; pfam13538
866344004163	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
866344004164	pH-dependent sodium/proton antiporter; Provisional; Region: nhaA; PRK14856
866344004165	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
866344004166	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
866344004167	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
866344004168	protein-export membrane protein SecF; Region: 3a0501s07; TIGR00966
866344004169	Protein export membrane protein; Region: SecD_SecF; pfam02355
866344004170	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
866344004171	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
866344004172	HIGH motif; other site
866344004173	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
866344004174	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
866344004175	active site
866344004176	KMSKS motif; other site
866344004177	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
866344004178	tRNA binding surface [nucleotide binding]; other site
866344004179	anticodon binding site; other site
866344004180	Lipopolysaccharide-assembly; Region: LptE; pfam04390
866344004181	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
866344004182	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866344004183	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866344004184	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
866344004185	Peptidase family M23; Region: Peptidase_M23; pfam01551
866344004186	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
866344004187	Peptidase family M23; Region: Peptidase_M23; pfam01551
866344004188	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
866344004189	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
866344004190	transcription-repair coupling factor (mfd); Region: mfd; TIGR00580
866344004191	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
866344004192	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866344004193	ATP binding site [chemical binding]; other site
866344004194	putative Mg++ binding site [ion binding]; other site
866344004195	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866344004196	nucleotide binding region [chemical binding]; other site
866344004197	ATP-binding site [chemical binding]; other site
866344004198	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
866344004199	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
866344004200	Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470
866344004201	[2Fe-2S] cluster binding site [ion binding]; other site
866344004202	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
866344004203	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
866344004204	intrachain domain interface; other site
866344004205	interchain domain interface [polypeptide binding]; other site
866344004206	heme bH binding site [chemical binding]; other site
866344004207	Qi binding site; other site
866344004208	heme bL binding site [chemical binding]; other site
866344004209	Qo binding site; other site
866344004210	interchain domain interface [polypeptide binding]; other site
866344004211	intrachain domain interface; other site
866344004212	Qi binding site; other site
866344004213	Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032
866344004214	Qo binding site; other site
866344004215	Cytochrome c1 [Energy production and conversion]; Region: CYT1; COG2857
866344004216	Cytochrome c; Region: Cytochrom_C; pfam00034
866344004217	Cytochrome c; Region: Cytochrom_C; cl11414
866344004218	synthase/transferase; Region: PLN02316
866344004219	Sulfatase; Region: Sulfatase; cl17466
866344004220	Sulfatase; Region: Sulfatase; cl17466
866344004221	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
866344004222	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
866344004223	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
866344004224	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK03907
866344004225	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
866344004226	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
866344004227	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
866344004228	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
866344004229	Cell cycle protein; Region: FTSW_RODA_SPOVE; pfam01098
866344004230	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
866344004231	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
866344004232	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
866344004233	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
866344004234	dimer interface [polypeptide binding]; other site
866344004235	decamer (pentamer of dimers) interface [polypeptide binding]; other site
866344004236	catalytic triad [active]
866344004237	peroxidatic and resolving cysteines [active]
866344004238	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
866344004239	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
866344004240	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
866344004241	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
866344004242	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
866344004243	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
866344004244	G1 box; other site
866344004245	GTP/Mg2+ binding site [chemical binding]; other site
866344004246	Switch I region; other site
866344004247	G2 box; other site
866344004248	G3 box; other site
866344004249	Switch II region; other site
866344004250	G4 box; other site
866344004251	G5 box; other site
866344004252	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
866344004253	OstA-like protein; Region: OstA; pfam03968
866344004254	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866344004255	motif II; other site
866344004256	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
866344004257	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
866344004258	Sporulation related domain; Region: SPOR; pfam05036
866344004259	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
866344004260	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
866344004261	N-acetyl-D-glucosamine binding site [chemical binding]; other site
866344004262	catalytic residue [active]
866344004263	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
866344004264	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
866344004265	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
866344004266	active site
866344004267	riboflavin synthase, alpha subunit; Region: ribE; TIGR00187
866344004268	Lumazine binding domain; Region: Lum_binding; pfam00677
866344004269	Lumazine binding domain; Region: Lum_binding; pfam00677
866344004270	flhB C-terminus-related protein; Region: flhB_rel; TIGR00789
866344004271	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
866344004272	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
866344004273	Walker A/P-loop; other site
866344004274	ATP binding site [chemical binding]; other site
866344004275	Q-loop/lid; other site
866344004276	ABC transporter signature motif; other site
866344004277	Walker B; other site
866344004278	D-loop; other site
866344004279	H-loop/switch region; other site
866344004280	NIL domain; Region: NIL; pfam09383
866344004281	ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]; Region: AbcD; COG2011
866344004282	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
866344004283	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
866344004284	active site
866344004285	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
866344004286	This subfamily is composed of uncharacterized bacterial glycosyltransferases in the MraY-like family. This family contains both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases, which...; Region: GT_MraY_like; cd06912
866344004287	Mg++ binding site [ion binding]; other site
866344004288	putative catalytic motif [active]
866344004289	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
866344004290	active site
866344004291	hydrophilic channel; other site
866344004292	dimerization interface [polypeptide binding]; other site
866344004293	catalytic residues [active]
866344004294	active site lid [active]
866344004295	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
866344004296	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK03946
866344004297	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
866344004298	metallohydrolase, glycoprotease/Kae1 family; Region: gcp_kae1; TIGR00329
866344004299	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
866344004300	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
866344004301	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
866344004302	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
866344004303	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
866344004304	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735