-- dump date   	20140619_113300
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
866346000001	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
866346000002	putative RNA binding site [nucleotide binding]; other site
866346000003	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
866346000004	homopentamer interface [polypeptide binding]; other site
866346000005	active site
866346000006	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
866346000007	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
866346000008	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
866346000009	active site clefts [active]
866346000010	zinc binding site [ion binding]; other site
866346000011	dimer interface [polypeptide binding]; other site
866346000012	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
866346000013	active site
866346000014	dimer interface [polypeptide binding]; other site
866346000015	pantoate--beta-alanine ligase; Region: panC; TIGR00018
866346000016	Pantoate-beta-alanine ligase; Region: PanC; cd00560
866346000017	active site
866346000018	ATP-binding site [chemical binding]; other site
866346000019	pantoate-binding site; other site
866346000020	HXXH motif; other site
866346000021	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346000022	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
866346000023	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
866346000024	ring oligomerisation interface [polypeptide binding]; other site
866346000025	ATP/Mg binding site [chemical binding]; other site
866346000026	stacking interactions; other site
866346000027	hinge regions; other site
866346000028	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
866346000029	oligomerisation interface [polypeptide binding]; other site
866346000030	mobile loop; other site
866346000031	roof hairpin; other site
866346000032	DNA primase, catalytic core; Region: dnaG; TIGR01391
866346000033	CHC2 zinc finger; Region: zf-CHC2; pfam01807
866346000034	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
866346000035	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
866346000036	active site
866346000037	metal binding site [ion binding]; metal-binding site
866346000038	interdomain interaction site; other site
866346000039	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
866346000040	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
866346000041	Ligand Binding Site [chemical binding]; other site
866346000042	TrbC/VIRB2 family; Region: TrbC; cl01583
866346000043	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
866346000044	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
866346000045	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
866346000046	Walker A motif; other site
866346000047	ATP binding site [chemical binding]; other site
866346000048	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
866346000049	Walker B motif; other site
866346000050	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
866346000051	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
866346000052	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
866346000053	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866346000054	active site
866346000055	phosphorylation site [posttranslational modification]
866346000056	intermolecular recognition site; other site
866346000057	dimerization interface [polypeptide binding]; other site
866346000058	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
866346000059	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
866346000060	dimer interface [polypeptide binding]; other site
866346000061	active site
866346000062	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866346000063	catalytic residues [active]
866346000064	substrate binding site [chemical binding]; other site
866346000065	lipid A 1-phosphatase; Reviewed; Region: PRK09597
866346000066	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
866346000067	active site
866346000068	lipid A phosphoethanolamine transferase; Reviewed; Region: PRK09598
866346000069	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
866346000070	Sulfatase; Region: Sulfatase; pfam00884
866346000071	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346000072	DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism]; Region: NUC1; COG1864
866346000073	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
866346000074	prephenate dehydrogenase; Validated; Region: PRK08507
866346000075	Prephenate dehydrogenase; Region: PDH; pfam02153
866346000076	ATP-dependent protease La; Region: lon; TIGR00763
866346000077	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346000078	Walker A motif; other site
866346000079	ATP binding site [chemical binding]; other site
866346000080	Walker B motif; other site
866346000081	arginine finger; other site
866346000082	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
866346000083	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
866346000084	flagellar assembly protein FliW; Provisional; Region: PRK13282
866346000085	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
866346000086	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
866346000087	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
866346000088	active site
866346000089	endopeptidase Clp ATP-binding regulatory subunit (clpX); Region: clpX; TIGR00382
866346000090	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
866346000091	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
866346000092	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346000093	Walker A motif; other site
866346000094	ATP binding site [chemical binding]; other site
866346000095	Walker B motif; other site
866346000096	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
866346000097	rod shape-determining protein MreB; Provisional; Region: PRK13927
866346000098	MreB and similar proteins; Region: MreB_like; cd10225
866346000099	nucleotide binding site [chemical binding]; other site
866346000100	Mg binding site [ion binding]; other site
866346000101	putative protofilament interaction site [polypeptide binding]; other site
866346000102	RodZ interaction site [polypeptide binding]; other site
866346000103	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
866346000104	rod shape-determining protein MreC; Region: MreC; pfam04085
866346000105	DEAD-like helicases superfamily; Region: DEXDc; smart00487
866346000106	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
866346000107	ATP binding site [chemical binding]; other site
866346000108	putative Mg++ binding site [ion binding]; other site
866346000109	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
866346000110	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346000111	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346000112	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
866346000113	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866346000114	active site
866346000115	phosphorylation site [posttranslational modification]
866346000116	intermolecular recognition site; other site
866346000117	dimerization interface [polypeptide binding]; other site
866346000118	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866346000119	DNA binding site [nucleotide binding]
866346000120	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
866346000121	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
866346000122	dimer interface [polypeptide binding]; other site
866346000123	phosphorylation site [posttranslational modification]
866346000124	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866346000125	ATP binding site [chemical binding]; other site
866346000126	Mg2+ binding site [ion binding]; other site
866346000127	G-X-G motif; other site
866346000128	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
866346000129	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
866346000130	putative substrate binding site [chemical binding]; other site
866346000131	putative ATP binding site [chemical binding]; other site
866346000132	replicative DNA helicase; Provisional; Region: PRK08506
866346000133	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
866346000134	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
866346000135	Walker A motif; other site
866346000136	ATP binding site [chemical binding]; other site
866346000137	Walker B motif; other site
866346000138	DNA binding loops [nucleotide binding]
866346000139	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
866346000140	Competence protein; Region: Competence; pfam03772
866346000141	prenyltransferase; Reviewed; Region: ubiA; PRK12874
866346000142	UbiA prenyltransferase family; Region: UbiA; pfam01040
866346000143	phosphatidylserine decarboxylase; Provisional; Region: PRK03934
866346000144	Quinolinate synthetase A protein; Region: NadA; cl00420
866346000145	nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK05848
866346000146	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
866346000147	dimerization interface [polypeptide binding]; other site
866346000148	active site
866346000149	Predicted helicase [General function prediction only]; Region: COG4889
866346000150	Predicted helicase [General function prediction only]; Region: COG4889
866346000151	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866346000152	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346000153	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
866346000154	C-terminal peptidase (prc); Region: prc; TIGR00225
866346000155	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
866346000156	protein binding site [polypeptide binding]; other site
866346000157	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
866346000158	Catalytic dyad [active]
866346000159	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
866346000160	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
866346000161	putative acyl-acceptor binding pocket; other site
866346000162	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
866346000163	ligand binding site [chemical binding]; other site
866346000164	active site
866346000165	UGI interface [polypeptide binding]; other site
866346000166	catalytic site [active]
866346000167	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
866346000168	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
866346000169	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
866346000170	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
866346000171	Phosphoglycerate kinase; Region: PGK; pfam00162
866346000172	substrate binding site [chemical binding]; other site
866346000173	hinge regions; other site
866346000174	ADP binding site [chemical binding]; other site
866346000175	catalytic site [active]
866346000176	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
866346000177	Mg2+ transporter Helicobacter pylori CorA-like subgroup; Region: HpCorA-like; cd12836
866346000178	Cl binding site [ion binding]; other site
866346000179	oligomer interface [polypeptide binding]; other site
866346000180	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
866346000181	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866346000182	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346000183	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
866346000184	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
866346000185	DNA binding site [nucleotide binding]
866346000186	substrate interaction site [chemical binding]; other site
866346000187	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
866346000188	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
866346000189	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
866346000190	Na binding site [ion binding]; other site
866346000191	Proline dehydrogenase; Region: Pro_dh; pfam01619
866346000192	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
866346000193	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
866346000194	Glutamate binding site [chemical binding]; other site
866346000195	NAD binding site [chemical binding]; other site
866346000196	catalytic residues [active]
866346000197	Proteins of 100 residues with WXG; Region: WXG100; cl02005
866346000198	A nuclease of the HNH/ENDO VII superfamily with conserved WHH; Region: WHH; pfam14414
866346000199	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
866346000200	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
866346000201	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
866346000202	Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829
866346000203	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
866346000204	G1 box; other site
866346000205	GTP/Mg2+ binding site [chemical binding]; other site
866346000206	G2 box; other site
866346000207	Switch I region; other site
866346000208	G3 box; other site
866346000209	Switch II region; other site
866346000210	G4 box; other site
866346000211	G5 box; other site
866346000212	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
866346000213	UreF; Region: UreF; pfam01730
866346000214	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
866346000215	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
866346000216	dimer interface [polypeptide binding]; other site
866346000217	catalytic residues [active]
866346000218	AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293
866346000219	urease subunit beta; Provisional; Region: ureB; PRK13985
866346000220	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
866346000221	subunit interactions [polypeptide binding]; other site
866346000222	active site
866346000223	flap region; other site
866346000224	urease subunit alpha; Provisional; Region: PRK13986
866346000225	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
866346000226	alpha-gamma subunit interface [polypeptide binding]; other site
866346000227	beta-gamma subunit interface [polypeptide binding]; other site
866346000228	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
866346000229	gamma-beta subunit interface [polypeptide binding]; other site
866346000230	alpha-beta subunit interface [polypeptide binding]; other site
866346000231	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
866346000232	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14324
866346000233	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
866346000234	active site
866346000235	substrate binding site [chemical binding]; other site
866346000236	metal binding site [ion binding]; metal-binding site
866346000237	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
866346000238	peptide chain release factor 1; Validated; Region: prfA; PRK00591
866346000239	This domain is found in peptide chain release factors; Region: PCRF; smart00937
866346000240	RF-1 domain; Region: RF-1; pfam00472
866346000241	potential frameshift: common BLAST hit: gi|108562505|ref|YP_626821.1| outer membrane protein HorA
866346000242	potential frameshift: common BLAST hit: gi|210134284|ref|YP_002300723.1| outer membrane protein HorA
866346000243	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346000244	potential frameshift: common BLAST hit: gi|15644712|ref|NP_206882.1| methyl-accepting chemotaxis transducer (tlpC)
866346000245	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
866346000246	dimer interface [polypeptide binding]; other site
866346000247	putative CheW interface [polypeptide binding]; other site
866346000248	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
866346000249	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
866346000250	23S rRNA interface [nucleotide binding]; other site
866346000251	L3 interface [polypeptide binding]; other site
866346000252	Predicted dehydrogenase [General function prediction only]; Region: COG0579
866346000253	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
866346000254	NLPC_P60 stabilising domain, N term; Region: N_NLPC_P60; pfam12912
866346000255	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
866346000256	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
866346000257	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
866346000258	NlpC/P60 family; Region: NLPC_P60; pfam00877
866346000259	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
866346000260	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
866346000261	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
866346000262	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
866346000263	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
866346000264	DNA binding residues [nucleotide binding]
866346000265	Protein of unknown function (DUF3991); Region: DUF3991; pfam13154
866346000266	Toprim-like; Region: Toprim_2; pfam13155
866346000267	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
866346000268	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
866346000269	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
866346000270	Walker A motif; other site
866346000271	ATP binding site [chemical binding]; other site
866346000272	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
866346000273	potential frameshift: common BLAST hit: gi|15645068|ref|NP_207238.1| DNA topoisomerase I (topA)
866346000274	Topoisomerase IA [DNA replication, recombination, and repair]; Region: TopA; COG0550
866346000275	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
866346000276	active site
866346000277	metal binding site [ion binding]; metal-binding site
866346000278	Bacterial DNA topoisomeraes I ATP-binding domain; Region: TOP1Bc; smart00436
866346000279	domain I; other site
866346000280	phosphate binding site [ion binding]; other site
866346000281	Topoisomerase IA [DNA replication, recombination, and repair]; Region: TopA; COG0550
866346000282	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cl11986
866346000283	domain II; other site
866346000284	domain III; other site
866346000285	nucleotide binding site [chemical binding]; other site
866346000286	DNA binding groove [nucleotide binding]
866346000287	catalytic site [active]
866346000288	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
866346000289	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346000290	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
866346000291	23S rRNA binding site [nucleotide binding]; other site
866346000292	L21 binding site [polypeptide binding]; other site
866346000293	L13 binding site [polypeptide binding]; other site
866346000294	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
866346000295	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
866346000296	translation initiation factor IF-3; Region: infC; TIGR00168
866346000297	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
866346000298	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
866346000299	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
866346000300	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
866346000301	active site
866346000302	dimer interface [polypeptide binding]; other site
866346000303	motif 1; other site
866346000304	motif 2; other site
866346000305	motif 3; other site
866346000306	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
866346000307	anticodon binding site; other site
866346000308	phosphoenolpyruvate synthase; Validated; Region: PRK06464
866346000309	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
866346000310	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
866346000311	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
866346000312	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
866346000313	Fe-S oxidoreductases [Energy production and conversion]; Region: COG0731
866346000314	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866346000315	FeS/SAM binding site; other site
866346000316	DNA topoisomerase I; Validated; Region: PRK05582
866346000317	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
866346000318	active site
866346000319	interdomain interaction site; other site
866346000320	putative metal-binding site [ion binding]; other site
866346000321	nucleotide binding site [chemical binding]; other site
866346000322	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
866346000323	domain I; other site
866346000324	DNA binding groove [nucleotide binding]
866346000325	phosphate binding site [ion binding]; other site
866346000326	domain II; other site
866346000327	domain III; other site
866346000328	nucleotide binding site [chemical binding]; other site
866346000329	catalytic site [active]
866346000330	domain IV; other site
866346000331	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
866346000332	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
866346000333	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
866346000334	flagellin B; Provisional; Region: PRK13588
866346000335	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
866346000336	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
866346000337	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
866346000338	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
866346000339	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
866346000340	hypothetical protein; Provisional; Region: PRK05834
866346000341	heat-inducible transcription repressor; Provisional; Region: PRK03911
866346000342	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
866346000343	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
866346000344	dimer interface [polypeptide binding]; other site
866346000345	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
866346000346	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
866346000347	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
866346000348	nucleotide binding site [chemical binding]; other site
866346000349	NEF interaction site [polypeptide binding]; other site
866346000350	SBD interface [polypeptide binding]; other site
866346000351	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
866346000352	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
866346000353	dimer interface [polypeptide binding]; other site
866346000354	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866346000355	catalytic residue [active]
866346000356	cystathionine gamma-synthase/cystathionine beta-lyase; Validated; Region: PRK06176
866346000357	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
866346000358	homodimer interface [polypeptide binding]; other site
866346000359	substrate-cofactor binding pocket; other site
866346000360	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866346000361	catalytic residue [active]
866346000362	S-ribosylhomocysteinase; Provisional; Region: PRK02260
866346000363	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
866346000364	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
866346000365	active site
866346000366	metal binding site [ion binding]; metal-binding site
866346000367	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
866346000368	Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049
866346000369	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
866346000370	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
866346000371	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
866346000372	dimer interface [polypeptide binding]; other site
866346000373	putative CheW interface [polypeptide binding]; other site
866346000374	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
866346000375	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
866346000376	metal-binding site
866346000377	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346000378	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases and ATP sulphurylases. The domain forms a apha/beta/apha fold which  binds to Adenosine group; Region: Alpha_ANH_like; cd01986
866346000379	Ligand Binding Site [chemical binding]; other site
866346000380	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
866346000381	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
866346000382	dimer interface [polypeptide binding]; other site
866346000383	putative CheW interface [polypeptide binding]; other site
866346000384	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
866346000385	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
866346000386	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866346000387	catalytic residue [active]
866346000388	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
866346000389	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
866346000390	putative ligand binding site [chemical binding]; other site
866346000391	putative NAD binding site [chemical binding]; other site
866346000392	catalytic site [active]
866346000393	Alpha-1,2-fucosyltransferase; Region: Fut1_Fut2_like; cd11301
866346000394	Glycosyl transferase family 11; Region: Glyco_transf_11; pfam01531
866346000395	GDP-Fucose binding site [chemical binding]; other site
866346000396	potential frameshift: common BLAST hit: gi|188526898|ref|YP_001909585.1| type I restriction enzyme M protein HsdM
866346000397	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866346000398	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346000399	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866346000400	Methyltransferase domain; Region: Methyltransf_26; pfam13659
866346000401	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346000402	Protein of unknown function (DUF511); Region: DUF511; pfam04373
866346000403	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
866346000404	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
866346000405	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
866346000406	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
866346000407	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
866346000408	active site
866346000409	catalytic residues [active]
866346000410	DNA binding site [nucleotide binding]
866346000411	Int/Topo IB signature motif; other site
866346000412	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
866346000413	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
866346000414	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
866346000415	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
866346000416	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
866346000417	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
866346000418	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
866346000419	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroG; COG3200
866346000420	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
866346000421	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
866346000422	catalytic triad [active]
866346000423	Uncharacterized conserved protein [Function unknown]; Region: COG1556
866346000424	iron-sulfur cluster-binding protein; Region: TIGR00273
866346000425	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
866346000426	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
866346000427	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
866346000428	Cysteine-rich domain; Region: CCG; pfam02754
866346000429	Cysteine-rich domain; Region: CCG; pfam02754
866346000430	L-lactate transport; Region: lctP; TIGR00795
866346000431	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
866346000432	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
866346000433	L-lactate permease; Region: Lactate_perm; pfam02652
866346000434	DNA glycosylase MutY; Provisional; Region: PRK13910
866346000435	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
866346000436	minor groove reading motif; other site
866346000437	helix-hairpin-helix signature motif; other site
866346000438	substrate binding pocket [chemical binding]; other site
866346000439	active site
866346000440	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
866346000441	DNA binding and oxoG recognition site [nucleotide binding]
866346000442	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
866346000443	Sodium:sulfate symporter transmembrane region; Region: Na_sulph_symp; pfam00939
866346000444	transmembrane helices; other site
866346000445	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
866346000446	Low-spin heme binding site [chemical binding]; other site
866346000447	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
866346000448	D-pathway; other site
866346000449	Putative water exit pathway; other site
866346000450	Binuclear center (active site) [active]
866346000451	K-pathway; other site
866346000452	Putative proton exit pathway; other site
866346000453	Cbb3-type cytochrome oxidase, cytochrome c subunit [Energy production and conversion]; Region: CcoO; COG2993
866346000454	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; cl01130
866346000455	cytochrome c oxidase, cbb3-type, CcoQ subunit, epsilon-Proteobacterial; Region: cbb3_Q_epsi; TIGR02736
866346000456	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
866346000457	Cytochrome c; Region: Cytochrom_C; pfam00034
866346000458	Cytochrome c; Region: Cytochrom_C; pfam00034
866346000459	Family of unknown function (DUF4006); Region: DUF4006; pfam13179
866346000460	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
866346000461	recombinase A; Provisional; Region: recA; PRK09354
866346000462	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
866346000463	hexamer interface [polypeptide binding]; other site
866346000464	Walker A motif; other site
866346000465	ATP binding site [chemical binding]; other site
866346000466	Walker B motif; other site
866346000467	enolase; Provisional; Region: eno; PRK00077
866346000468	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
866346000469	dimer interface [polypeptide binding]; other site
866346000470	metal binding site [ion binding]; metal-binding site
866346000471	substrate binding pocket [chemical binding]; other site
866346000472	AMIN domain; Region: AMIN; pfam11741
866346000473	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
866346000474	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
866346000475	ADP binding site [chemical binding]; other site
866346000476	magnesium binding site [ion binding]; other site
866346000477	putative shikimate binding site; other site
866346000478	Cache domain; Region: Cache_1; pfam02743
866346000479	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
866346000480	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
866346000481	Ligand binding site; other site
866346000482	metal-binding site
866346000483	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866346000484	Sel1-like repeats; Region: SEL1; smart00671
866346000485	Sel1-like repeats; Region: SEL1; smart00671
866346000486	Sel1-like repeats; Region: SEL1; smart00671
866346000487	Sel1-like repeats; Region: SEL1; smart00671
866346000488	Sel1-like repeats; Region: SEL1; smart00671
866346000489	Sel1-like repeats; Region: SEL1; smart00671
866346000490	hypothetical protein; Provisional; Region: PRK12378
866346000491	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
866346000492	dimer interface [polypeptide binding]; other site
866346000493	active site
866346000494	Schiff base residues; other site
866346000495	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
866346000496	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
866346000497	dimerization interface [polypeptide binding]; other site
866346000498	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866346000499	dimer interface [polypeptide binding]; other site
866346000500	phosphorylation site [posttranslational modification]
866346000501	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866346000502	ATP binding site [chemical binding]; other site
866346000503	Mg2+ binding site [ion binding]; other site
866346000504	G-X-G motif; other site
866346000505	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
866346000506	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866346000507	active site
866346000508	phosphorylation site [posttranslational modification]
866346000509	intermolecular recognition site; other site
866346000510	dimerization interface [polypeptide binding]; other site
866346000511	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866346000512	DNA binding site [nucleotide binding]
866346000513	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
866346000514	Peptidase family U32; Region: Peptidase_U32; pfam01136
866346000515	peptide chain release factor 2; Region: prfB; TIGR00020
866346000516	This domain is found in peptide chain release factors; Region: PCRF; smart00937
866346000517	RF-1 domain; Region: RF-1; pfam00472
866346000518	potential frameshift: common BLAST hit: gi|308182346|ref|YP_003926473.1| molybdopterin biosynthesis protein
866346000519	MoCF_BD: molybdenum cofactor (MoCF) binding domain (BD). This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor, like MoaB, MogA, and MoeA. The domain is presumed to bind molybdopterin; Region: MoCF_BD; cl00451
866346000520	MoeA N-terminal region (domain I and II); Region: MoeA_N; pfam03453
866346000521	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
866346000522	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
866346000523	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
866346000524	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
866346000525	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
866346000526	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
866346000527	intersubunit interface [polypeptide binding]; other site
866346000528	active site
866346000529	zinc binding site [ion binding]; other site
866346000530	Na+ binding site [ion binding]; other site
866346000531	elongation factor P; Validated; Region: PRK00529
866346000532	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
866346000533	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
866346000534	RNA binding site [nucleotide binding]; other site
866346000535	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
866346000536	RNA binding site [nucleotide binding]; other site
866346000537	pseudaminic acid synthase; Region: PseI; TIGR03586
866346000538	NeuB family; Region: NeuB; pfam03102
866346000539	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
866346000540	NeuB binding interface [polypeptide binding]; other site
866346000541	putative substrate binding site [chemical binding]; other site
866346000542	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
866346000543	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
866346000544	Walker A/P-loop; other site
866346000545	ATP binding site [chemical binding]; other site
866346000546	Q-loop/lid; other site
866346000547	ABC transporter signature motif; other site
866346000548	Walker B; other site
866346000549	D-loop; other site
866346000550	H-loop/switch region; other site
866346000551	apolipoprotein N-acyltransferase; Reviewed; Region: PRK12291
866346000552	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
866346000553	active site
866346000554	catalytic triad [active]
866346000555	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
866346000556	Colicin V production protein; Region: Colicin_V; pfam02674
866346000557	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
866346000558	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
866346000559	dimer interface [polypeptide binding]; other site
866346000560	putative anticodon binding site; other site
866346000561	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
866346000562	motif 1; other site
866346000563	active site
866346000564	motif 2; other site
866346000565	motif 3; other site
866346000566	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
866346000567	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
866346000568	dimer interface [polypeptide binding]; other site
866346000569	active site
866346000570	glycine-pyridoxal phosphate binding site [chemical binding]; other site
866346000571	folate binding site [chemical binding]; other site
866346000572	Domain of unknown function (DUF1882); Region: DUF1882; pfam08966
866346000573	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
866346000574	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866346000575	Uncharacterized protein family, UPF0114; Region: UPF0114; cl01078
866346000576	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
866346000577	PLD-like domain; Region: PLDc_2; pfam13091
866346000578	putative active site [active]
866346000579	catalytic site [active]
866346000580	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
866346000581	PLD-like domain; Region: PLDc_2; pfam13091
866346000582	putative active site [active]
866346000583	catalytic site [active]
866346000584	fumarate reductase iron-sulfur subunit; Provisional; Region: frdB; PRK13552
866346000585	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
866346000586	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866346000587	fumarate reductase flavoprotein subunit; Provisional; Region: PRK08626
866346000588	L-aspartate oxidase; Provisional; Region: PRK06175
866346000589	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
866346000590	fumarate reductase cytochrome b-556 subunit; Provisional; Region: PRK13553
866346000591	Quinol:fumarate reductase (QFR) Type B subfamily, transmembrane subunit;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinone...; Region: QFR_TypeB_TM; cd00581
866346000592	Iron-sulfur protein interface; other site
866346000593	proximal heme binding site [chemical binding]; other site
866346000594	distal heme binding site [chemical binding]; other site
866346000595	dimer interface [polypeptide binding]; other site
866346000596	triosephosphate isomerase; Provisional; Region: PRK14567
866346000597	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
866346000598	substrate binding site [chemical binding]; other site
866346000599	dimer interface [polypeptide binding]; other site
866346000600	catalytic triad [active]
866346000601	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08415
866346000602	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
866346000603	NAD binding site [chemical binding]; other site
866346000604	homotetramer interface [polypeptide binding]; other site
866346000605	homodimer interface [polypeptide binding]; other site
866346000606	substrate binding site [chemical binding]; other site
866346000607	active site
866346000608	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
866346000609	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
866346000610	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
866346000611	trimer interface [polypeptide binding]; other site
866346000612	active site
866346000613	UDP-GlcNAc binding site [chemical binding]; other site
866346000614	lipid binding site [chemical binding]; lipid-binding site
866346000615	S-adenosylmethionine synthetase; Validated; Region: PRK05250
866346000616	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
866346000617	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
866346000618	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
866346000619	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
866346000620	active site
866346000621	multimer interface [polypeptide binding]; other site
866346000622	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
866346000623	fatty acid/phospholipid synthesis protein PlsX; Region: plsX; TIGR00182
866346000624	3-oxoacyl-(acyl-carrier-protein) synthase III; Region: fabH; TIGR00747
866346000625	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
866346000626	dimer interface [polypeptide binding]; other site
866346000627	active site
866346000628	CoA binding pocket [chemical binding]; other site
866346000629	AAA ATPase domain; Region: AAA_15; pfam13175
866346000630	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
866346000631	Walker B; other site
866346000632	D-loop; other site
866346000633	H-loop/switch region; other site
866346000634	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866346000635	Walker A/P-loop; other site
866346000636	ATP binding site [chemical binding]; other site
866346000637	antiporter inner membrane protein; Provisional; Region: PRK11670
866346000638	Domain of unknown function DUF59; Region: DUF59; pfam01883
866346000639	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
866346000640	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
866346000641	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
866346000642	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866346000643	heat shock protein 90; Provisional; Region: PRK05218
866346000644	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866346000645	ATP binding site [chemical binding]; other site
866346000646	Mg2+ binding site [ion binding]; other site
866346000647	G-X-G motif; other site
866346000648	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866346000649	Sel1-like repeats; Region: SEL1; smart00671
866346000650	Sel1-like repeats; Region: SEL1; smart00671
866346000651	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866346000652	TPR motif; other site
866346000653	binding surface
866346000654	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
866346000655	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
866346000656	metal binding site [ion binding]; metal-binding site
866346000657	dimer interface [polypeptide binding]; other site
866346000658	glucose-inhibited division protein A; Region: gidA; TIGR00136
866346000659	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866346000660	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
866346000661	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
866346000662	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
866346000663	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
866346000664	transmembrane helices; other site
866346000665	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
866346000666	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
866346000667	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: Dxr; TIGR00243
866346000668	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
866346000669	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
866346000670	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
866346000671	Beta-1,4-N-acetylgalactosaminyltransferase (CgtA); Region: CgtA; pfam06306
866346000672	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
866346000673	substrate binding site [chemical binding]; other site
866346000674	Helix-turn-helix domain; Region: HTH_28; pfam13518
866346000675	cysteine desulfurase, NifS family, epsilon proteobacteria type; Region: nifS_epsilon; TIGR03403
866346000676	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
866346000677	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866346000678	catalytic residue [active]
866346000679	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
866346000680	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
866346000681	trimerization site [polypeptide binding]; other site
866346000682	active site
866346000683	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
866346000684	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
866346000685	DNA repair protein RadA; Region: sms; TIGR00416
866346000686	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
866346000687	Walker A motif/ATP binding site; other site
866346000688	ATP binding site [chemical binding]; other site
866346000689	Walker B motif; other site
866346000690	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
866346000691	Peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: MsrA; COG0225
866346000692	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
866346000693	SelR domain; Region: SelR; pfam01641
866346000694	Predicted permeases [General function prediction only]; Region: COG0730
866346000695	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346000696	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
866346000697	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
866346000698	Sulfate transporter family; Region: Sulfate_transp; pfam00916
866346000699	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346000700	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
866346000701	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
866346000702	Ligand binding site; other site
866346000703	oligomer interface; other site
866346000704	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
866346000705	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
866346000706	hypothetical protein; Provisional; Region: PRK04081
866346000707	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
866346000708	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3295
866346000709	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866346000710	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866346000711	binding surface
866346000712	TPR motif; other site
866346000713	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866346000714	binding surface
866346000715	TPR motif; other site
866346000716	Sel1-like repeats; Region: SEL1; smart00671
866346000717	Sel1-like repeats; Region: SEL1; smart00671
866346000718	Cytochrome c; Region: Cytochrom_C; cl11414
866346000719	Porphobilinogen deaminase [Coenzyme metabolism]; Region: HemC; COG0181
866346000720	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
866346000721	domain interfaces; other site
866346000722	active site
866346000723	prolyl-tRNA synthetase, family II; Region: proS_fam_II; TIGR00409
866346000724	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
866346000725	dimer interface [polypeptide binding]; other site
866346000726	motif 1; other site
866346000727	active site
866346000728	motif 2; other site
866346000729	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
866346000730	putative deacylase active site [active]
866346000731	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
866346000732	active site
866346000733	motif 3; other site
866346000734	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
866346000735	anticodon binding site; other site
866346000736	glutamyl-tRNA reductase; Region: hemA; TIGR01035
866346000737	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
866346000738	tRNA; other site
866346000739	putative tRNA binding site [nucleotide binding]; other site
866346000740	putative NADP binding site [chemical binding]; other site
866346000741	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
866346000742	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
866346000743	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
866346000744	substrate binding pocket [chemical binding]; other site
866346000745	chain length determination region; other site
866346000746	substrate-Mg2+ binding site; other site
866346000747	catalytic residues [active]
866346000748	aspartate-rich region 1; other site
866346000749	active site lid residues [active]
866346000750	aspartate-rich region 2; other site
866346000751	Domain of unknown function (DUF2018); Region: DUF2018; pfam09442
866346000752	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
866346000753	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
866346000754	dimerization interface [polypeptide binding]; other site
866346000755	DPS ferroxidase diiron center [ion binding]; other site
866346000756	ion pore; other site
866346000757	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
866346000758	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866346000759	dimer interface [polypeptide binding]; other site
866346000760	phosphorylation site [posttranslational modification]
866346000761	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866346000762	ATP binding site [chemical binding]; other site
866346000763	Mg2+ binding site [ion binding]; other site
866346000764	G-X-G motif; other site
866346000765	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
866346000766	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
866346000767	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
866346000768	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
866346000769	ATP binding site [chemical binding]; other site
866346000770	Mg++ binding site [ion binding]; other site
866346000771	motif III; other site
866346000772	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866346000773	nucleotide binding region [chemical binding]; other site
866346000774	ATP-binding site [chemical binding]; other site
866346000775	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
866346000776	SPFH domain / Band 7 family; Region: Band_7; pfam01145
866346000777	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
866346000778	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
866346000779	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866346000780	Walker A/P-loop; other site
866346000781	ATP binding site [chemical binding]; other site
866346000782	Q-loop/lid; other site
866346000783	ABC transporter signature motif; other site
866346000784	Walker B; other site
866346000785	D-loop; other site
866346000786	H-loop/switch region; other site
866346000787	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
866346000788	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866346000789	Walker A/P-loop; other site
866346000790	ATP binding site [chemical binding]; other site
866346000791	Q-loop/lid; other site
866346000792	ABC transporter signature motif; other site
866346000793	Walker B; other site
866346000794	D-loop; other site
866346000795	H-loop/switch region; other site
866346000796	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
866346000797	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
866346000798	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866346000799	dimer interface [polypeptide binding]; other site
866346000800	conserved gate region; other site
866346000801	putative PBP binding loops; other site
866346000802	ABC-ATPase subunit interface; other site
866346000803	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346000804	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346000805	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
866346000806	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
866346000807	GDP-binding site [chemical binding]; other site
866346000808	ACT binding site; other site
866346000809	IMP binding site; other site
866346000810	Flagellar FliJ protein; Region: FliJ; pfam02050
866346000811	Uncharacterized conserved protein [Function unknown]; Region: COG3334
866346000812	RIP metalloprotease RseP; Region: TIGR00054
866346000813	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
866346000814	active site
866346000815	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
866346000816	protein binding site [polypeptide binding]; other site
866346000817	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
866346000818	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
866346000819	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
866346000820	generic binding surface II; other site
866346000821	generic binding surface I; other site
866346000822	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
866346000823	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346000824	Toprim-like; Region: Toprim_2; pfam13155
866346000825	Type IV secretory pathway, VirB4 components [Intracellular trafficking and secretion]; Region: VirB4; COG3451
866346000826	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
866346000827	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
866346000828	Domain of unknown function DUF87; Region: DUF87; pfam01935
866346000829	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
866346000830	Topoisomerase IA [DNA replication, recombination, and repair]; Region: TopA; COG0550
866346000831	TOPRIM_TopoIA: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in the type IA family of DNA topoisomerases (TopoIA). This subgroup contains proteins similar to the Type I DNA topoisomerases: E. coli...; Region: TOPRIM_TopoIA; cd01028
866346000832	active site
866346000833	interdomain interaction site; other site
866346000834	putative metal-binding site [ion binding]; other site
866346000835	nucleotide binding site [chemical binding]; other site
866346000836	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cl11986
866346000837	domain I; other site
866346000838	DNA binding groove [nucleotide binding]
866346000839	phosphate binding site [ion binding]; other site
866346000840	domain II; other site
866346000841	domain III; other site
866346000842	nucleotide binding site [chemical binding]; other site
866346000843	catalytic site [active]
866346000844	domain IV; other site
866346000845	VirB8 protein; Region: VirB8; cl01500
866346000846	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
866346000847	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
866346000848	VirB7 interaction site; other site
866346000849	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
866346000850	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
866346000851	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
866346000852	Walker A motif; other site
866346000853	hexamer interface [polypeptide binding]; other site
866346000854	ATP binding site [chemical binding]; other site
866346000855	Walker B motif; other site
866346000856	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
866346000857	Walker A motif; other site
866346000858	ATP binding site [chemical binding]; other site
866346000859	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
866346000860	TraM recognition site of TraD and TraG; Region: TraG-D_C; pfam12696
866346000861	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
866346000862	Type IV secretory pathway, VirD2 components (relaxase) [Intracellular trafficking and secretion]; Region: VirD2; COG3843
866346000863	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
866346000864	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
866346000865	P-loop; other site
866346000866	Magnesium ion binding site [ion binding]; other site
866346000867	Methyltransferase domain; Region: Methyltransf_26; pfam13659
866346000868	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
866346000869	DEAD-like helicases superfamily; Region: DEXDc; smart00487
866346000870	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
866346000871	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
866346000872	helicase superfamily c-terminal domain; Region: HELICc; smart00490
866346000873	nucleotide binding region [chemical binding]; other site
866346000874	ATP-binding site [chemical binding]; other site
866346000875	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
866346000876	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
866346000877	active site
866346000878	catalytic residues [active]
866346000879	DNA binding site [nucleotide binding]
866346000880	Int/Topo IB signature motif; other site
866346000881	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346000882	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
866346000883	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866346000884	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346000885	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
866346000886	Clp amino terminal domain; Region: Clp_N; pfam02861
866346000887	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346000888	Walker A motif; other site
866346000889	ATP binding site [chemical binding]; other site
866346000890	Walker B motif; other site
866346000891	arginine finger; other site
866346000892	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346000893	Walker A motif; other site
866346000894	ATP binding site [chemical binding]; other site
866346000895	Walker B motif; other site
866346000896	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
866346000897	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
866346000898	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
866346000899	Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; Region: PyrC; COG0044
866346000900	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
866346000901	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
866346000902	active site
866346000903	chlorohydrolase; Provisional; Region: PRK08418
866346000904	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_D; cd01312
866346000905	active site
866346000906	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
866346000907	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14339
866346000908	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866346000909	FeS/SAM binding site; other site
866346000910	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
866346000911	putative acyl-acceptor binding pocket; other site
866346000912	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
866346000913	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
866346000914	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
866346000915	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
866346000916	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
866346000917	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
866346000918	putative active site [active]
866346000919	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
866346000920	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
866346000921	putative acyl-acceptor binding pocket; other site
866346000922	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
866346000923	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
866346000924	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3400
866346000925	TrkA-C domain; Region: TrkA_C; pfam02080
866346000926	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
866346000927	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
866346000928	active site
866346000929	dimer interface [polypeptide binding]; other site
866346000930	metal binding site [ion binding]; metal-binding site
866346000931	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
866346000932	Mechanosensitive ion channel; Region: MS_channel; pfam00924
866346000933	radical SAM methylthiotransferase, MiaB/RimO family; Region: TIGR00089
866346000934	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
866346000935	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866346000936	FeS/SAM binding site; other site
866346000937	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
866346000938	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346000939	Walker A motif; other site
866346000940	ATP binding site [chemical binding]; other site
866346000941	Walker B motif; other site
866346000942	arginine finger; other site
866346000943	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
866346000944	Domain of unknown function (DUF4149); Region: DUF4149; pfam13664
866346000945	Vacuolating cyotoxin; Region: VacA; pfam02691
866346000946	Autotransporter beta-domain; Region: Autotransporter; pfam03797
866346000947	diaminopimelate decarboxylase; Region: lysA; TIGR01048
866346000948	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
866346000949	active site
866346000950	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866346000951	substrate binding site [chemical binding]; other site
866346000952	catalytic residues [active]
866346000953	dimer interface [polypeptide binding]; other site
866346000954	Chorismate mutase [Amino acid transport and metabolism]; Region: PheA; COG1605
866346000955	Uncharacterized conserved protein [Function unknown]; Region: COG4866
866346000956	aminodeoxychorismate synthase; Provisional; Region: PRK07508
866346000957	chorismate binding enzyme; Region: Chorismate_bind; cl10555
866346000958	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
866346000959	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
866346000960	substrate-cofactor binding pocket; other site
866346000961	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866346000962	catalytic residue [active]
866346000963	acylamide amidohydrolase; Provisional; Region: amiE; PRK13286
866346000964	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
866346000965	multimer interface [polypeptide binding]; other site
866346000966	active site
866346000967	catalytic triad [active]
866346000968	dimer interface [polypeptide binding]; other site
866346000969	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK08412
866346000970	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
866346000971	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
866346000972	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
866346000973	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
866346000974	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
866346000975	peptide binding site [polypeptide binding]; other site
866346000976	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
866346000977	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866346000978	dimer interface [polypeptide binding]; other site
866346000979	conserved gate region; other site
866346000980	putative PBP binding loops; other site
866346000981	ABC-ATPase subunit interface; other site
866346000982	dipeptide transporter; Provisional; Region: PRK10913
866346000983	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
866346000984	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866346000985	dimer interface [polypeptide binding]; other site
866346000986	conserved gate region; other site
866346000987	putative PBP binding loops; other site
866346000988	ABC-ATPase subunit interface; other site
866346000989	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866346000990	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
866346000991	Walker A/P-loop; other site
866346000992	ATP binding site [chemical binding]; other site
866346000993	Q-loop/lid; other site
866346000994	ABC transporter signature motif; other site
866346000995	Walker B; other site
866346000996	D-loop; other site
866346000997	H-loop/switch region; other site
866346000998	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
866346000999	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
866346001000	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866346001001	Walker A/P-loop; other site
866346001002	ATP binding site [chemical binding]; other site
866346001003	Q-loop/lid; other site
866346001004	ABC transporter signature motif; other site
866346001005	Walker B; other site
866346001006	D-loop; other site
866346001007	H-loop/switch region; other site
866346001008	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
866346001009	GTPase CgtA; Reviewed; Region: obgE; PRK12299
866346001010	GTP1/OBG; Region: GTP1_OBG; pfam01018
866346001011	Obg GTPase; Region: Obg; cd01898
866346001012	G1 box; other site
866346001013	GTP/Mg2+ binding site [chemical binding]; other site
866346001014	Switch I region; other site
866346001015	G2 box; other site
866346001016	G3 box; other site
866346001017	Switch II region; other site
866346001018	G4 box; other site
866346001019	G5 box; other site
866346001020	Alginate lyase; Region: Alginate_lyase; pfam05426
866346001021	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
866346001022	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
866346001023	inhibitor-cofactor binding pocket; inhibition site
866346001024	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866346001025	catalytic residue [active]
866346001026	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
866346001027	Predicted amidohydrolase [General function prediction only]; Region: COG0388
866346001028	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
866346001029	active site
866346001030	catalytic triad [active]
866346001031	dimer interface [polypeptide binding]; other site
866346001032	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
866346001033	active site
866346001034	catalytic site [active]
866346001035	Zn binding site [ion binding]; other site
866346001036	tetramer interface [polypeptide binding]; other site
866346001037	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
866346001038	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866346001039	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346001040	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
866346001041	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
866346001042	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
866346001043	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
866346001044	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866346001045	putative substrate translocation pore; other site
866346001046	heme oxygenase, HugZ family; Region: heme_ox_HugZ; TIGR04109
866346001047	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
866346001048	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
866346001049	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
866346001050	arginyl-tRNA synthetase; Region: argS; TIGR00456
866346001051	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
866346001052	active site
866346001053	HIGH motif; other site
866346001054	KMSK motif region; other site
866346001055	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
866346001056	tRNA binding surface [nucleotide binding]; other site
866346001057	anticodon binding site; other site
866346001058	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
866346001059	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
866346001060	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
866346001061	catalytic site [active]
866346001062	G-X2-G-X-G-K; other site
866346001063	nuclease NucT; Provisional; Region: PRK13912
866346001064	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
866346001065	putative active site [active]
866346001066	catalytic site [active]
866346001067	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346001068	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
866346001069	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
866346001070	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
866346001071	ligand binding site; other site
866346001072	tetramer interface; other site
866346001073	Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: spsG; COG3980
866346001074	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
866346001075	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
866346001076	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
866346001077	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
866346001078	NAD synthetase; Provisional; Region: PRK13980
866346001079	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
866346001080	homodimer interface [polypeptide binding]; other site
866346001081	NAD binding pocket [chemical binding]; other site
866346001082	ATP binding pocket [chemical binding]; other site
866346001083	Mg binding site [ion binding]; other site
866346001084	active-site loop [active]
866346001085	ketol-acid reductoisomerase; Provisional; Region: PRK05479
866346001086	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
866346001087	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
866346001088	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
866346001089	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
866346001090	Switch I; other site
866346001091	Switch II; other site
866346001092	cell division topological specificity factor MinE; Region: minE; TIGR01215
866346001093	DNA protecting protein DprA; Region: dprA; TIGR00732
866346001094	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
866346001095	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
866346001096	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866346001097	Sel1-like repeats; Region: SEL1; smart00671
866346001098	Sel1 repeat; Region: Sel1; cl02723
866346001099	chlorohydrolase; Provisional; Region: PRK07213
866346001100	catalytic residue [active]
866346001101	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
866346001102	Predicted membrane protein [Function unknown]; Region: COG3326
866346001103	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
866346001104	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
866346001105	active site
866346001106	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
866346001107	DHH family; Region: DHH; pfam01368
866346001108	DHHA1 domain; Region: DHHA1; pfam02272
866346001109	CTP synthetase; Validated; Region: pyrG; PRK05380
866346001110	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
866346001111	Catalytic site [active]
866346001112	active site
866346001113	UTP binding site [chemical binding]; other site
866346001114	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
866346001115	active site
866346001116	putative oxyanion hole; other site
866346001117	catalytic triad [active]
866346001118	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
866346001119	active site
866346001120	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
866346001121	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
866346001122	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
866346001123	flagellar motor switch protein FliG; Region: fliG; TIGR00207
866346001124	FliG C-terminal domain; Region: FliG_C; pfam01706
866346001125	flagellar assembly protein H; Validated; Region: fliH; PRK06669
866346001126	Flagellar assembly protein FliH; Region: FliH; pfam02108
866346001127	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
866346001128	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
866346001129	TPP-binding site; other site
866346001130	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
866346001131	PYR/PP interface [polypeptide binding]; other site
866346001132	dimer interface [polypeptide binding]; other site
866346001133	TPP binding site [chemical binding]; other site
866346001134	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
866346001135	GTP-binding protein LepA; Provisional; Region: PRK05433
866346001136	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
866346001137	G1 box; other site
866346001138	putative GEF interaction site [polypeptide binding]; other site
866346001139	GTP/Mg2+ binding site [chemical binding]; other site
866346001140	Switch I region; other site
866346001141	G2 box; other site
866346001142	G3 box; other site
866346001143	Switch II region; other site
866346001144	G4 box; other site
866346001145	G5 box; other site
866346001146	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
866346001147	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
866346001148	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
866346001149	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
866346001150	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
866346001151	cofactor binding site; other site
866346001152	DNA binding site [nucleotide binding]
866346001153	substrate interaction site [chemical binding]; other site
866346001154	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
866346001155	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
866346001156	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
866346001157	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866346001158	putative substrate translocation pore; other site
866346001159	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
866346001160	TspO/MBR family; Region: TspO_MBR; cl01379
866346001161	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
866346001162	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
866346001163	Inactivated superfamily I helicase [DNA replication, recombination, and repair]; Region: COG3893
866346001164	RecB family exonuclease [DNA replication, recombination, and repair]; Region: COG2887
866346001165	transketolase, bacterial and yeast; Region: tktlase_bact; TIGR00232
866346001166	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
866346001167	TPP-binding site [chemical binding]; other site
866346001168	dimer interface [polypeptide binding]; other site
866346001169	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
866346001170	PYR/PP interface [polypeptide binding]; other site
866346001171	dimer interface [polypeptide binding]; other site
866346001172	TPP binding site [chemical binding]; other site
866346001173	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
866346001174	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
866346001175	riboflavin kinase/FMN adenylyltransferase; Region: ribF; TIGR00083
866346001176	active site
866346001177	Riboflavin kinase; Region: Flavokinase; smart00904
866346001178	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866346001179	hemolysin TlyA family protein; Region: tly; TIGR00478
866346001180	RNA binding surface [nucleotide binding]; other site
866346001181	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866346001182	S-adenosylmethionine binding site [chemical binding]; other site
866346001183	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
866346001184	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
866346001185	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
866346001186	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866346001187	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
866346001188	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
866346001189	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866346001190	Walker A/P-loop; other site
866346001191	ATP binding site [chemical binding]; other site
866346001192	Q-loop/lid; other site
866346001193	ABC transporter signature motif; other site
866346001194	Walker B; other site
866346001195	D-loop; other site
866346001196	H-loop/switch region; other site
866346001197	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
866346001198	Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes [Defense mechanisms]; Region: COG1787
866346001199	Restriction endonuclease; Region: Mrr_cat; pfam04471
866346001200	Predicted ATPases [General function prediction only]; Region: COG1106
866346001201	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866346001202	Walker A/P-loop; other site
866346001203	ATP binding site [chemical binding]; other site
866346001204	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
866346001205	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cd00596
866346001206	active site
866346001207	Zn binding site [ion binding]; other site
866346001208	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
866346001209	metal-binding site [ion binding]
866346001210	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
866346001211	metal-binding site [ion binding]
866346001212	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
866346001213	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
866346001214	Soluble P-type ATPase [General function prediction only]; Region: COG4087
866346001215	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
866346001216	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
866346001217	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
866346001218	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346001219	Walker A motif; other site
866346001220	ATP binding site [chemical binding]; other site
866346001221	Walker B motif; other site
866346001222	arginine finger; other site
866346001223	Peptidase family M41; Region: Peptidase_M41; pfam01434
866346001224	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
866346001225	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866346001226	S-adenosylmethionine binding site [chemical binding]; other site
866346001227	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
866346001228	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866346001229	active site
866346001230	phosphorylation site [posttranslational modification]
866346001231	intermolecular recognition site; other site
866346001232	dimerization interface [polypeptide binding]; other site
866346001233	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346001234	rRNA small subunit methyltransferase G; Region: GidB; pfam02527
866346001235	16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Region: gidB; TIGR00138
866346001236	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
866346001237	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
866346001238	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
866346001239	sec-independent translocase; Provisional; Region: PRK04098
866346001240	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
866346001241	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346001242	Walker A motif; other site
866346001243	ATP binding site [chemical binding]; other site
866346001244	Walker B motif; other site
866346001245	arginine finger; other site
866346001246	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
866346001247	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
866346001248	oligomerization interface [polypeptide binding]; other site
866346001249	active site
866346001250	metal binding site [ion binding]; metal-binding site
866346001251	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346001252	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346001253	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
866346001254	septum formation inhibitor; Reviewed; Region: minC; PRK00556
866346001255	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
866346001256	UDP-3-0-acyl N-acetylglucosamine deacetylase; Region: lpxC; TIGR00325
866346001257	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
866346001258	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
866346001259	homoserine kinase; Region: thrB; TIGR00191
866346001260	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
866346001261	Predicted nucleic-acid-binding protein implicated in transcription termination [Transcription]; Region: COG2740
866346001262	putative RNA binding cleft [nucleotide binding]; other site
866346001263	translation initiation factor IF-2; Region: IF-2; TIGR00487
866346001264	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
866346001265	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
866346001266	G1 box; other site
866346001267	putative GEF interaction site [polypeptide binding]; other site
866346001268	GTP/Mg2+ binding site [chemical binding]; other site
866346001269	Switch I region; other site
866346001270	G2 box; other site
866346001271	G3 box; other site
866346001272	Switch II region; other site
866346001273	G4 box; other site
866346001274	G5 box; other site
866346001275	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
866346001276	Translation-initiation factor 2; Region: IF-2; pfam11987
866346001277	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
866346001278	Ribosome-binding factor A; Region: RBFA; cl00542
866346001279	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
866346001280	Sm and related proteins; Region: Sm_like; cl00259
866346001281	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
866346001282	putative oligomer interface [polypeptide binding]; other site
866346001283	putative RNA binding site [nucleotide binding]; other site
866346001284	acetyl-CoA synthetase; Provisional; Region: PRK00174
866346001285	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
866346001286	active site
866346001287	CoA binding site [chemical binding]; other site
866346001288	acyl-activating enzyme (AAE) consensus motif; other site
866346001289	AMP binding site [chemical binding]; other site
866346001290	acetate binding site [chemical binding]; other site
866346001291	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
866346001292	putative active site [active]
866346001293	putative metal binding site [ion binding]; other site
866346001294	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
866346001295	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
866346001296	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866346001297	active site
866346001298	intermolecular recognition site; other site
866346001299	dimerization interface [polypeptide binding]; other site
866346001300	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866346001301	DNA binding site [nucleotide binding]
866346001302	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
866346001303	DHH family; Region: DHH; pfam01368
866346001304	flagellar biosynthesis protein FlhA; Region: FlhA; TIGR01398
866346001305	FHIPEP family; Region: FHIPEP; pfam00771
866346001306	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
866346001307	16S/18S rRNA binding site [nucleotide binding]; other site
866346001308	S13e-L30e interaction site [polypeptide binding]; other site
866346001309	25S rRNA binding site [nucleotide binding]; other site
866346001310	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
866346001311	O-Antigen ligase; Region: Wzy_C; pfam04932
866346001312	Dehydroquinase class II; Region: DHquinase_II; pfam01220
866346001313	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
866346001314	trimer interface [polypeptide binding]; other site
866346001315	active site
866346001316	dimer interface [polypeptide binding]; other site
866346001317	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
866346001318	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
866346001319	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
866346001320	active site
866346001321	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
866346001322	catalytic center binding site [active]
866346001323	ATP binding site [chemical binding]; other site
866346001324	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
866346001325	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
866346001326	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
866346001327	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
866346001328	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
866346001329	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
866346001330	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
866346001331	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
866346001332	DNA binding residues [nucleotide binding]
866346001333	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
866346001334	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
866346001335	flagellar motor switch protein FliY; Validated; Region: PRK08432
866346001336	flagellar motor switch protein FliN; Region: fliN; TIGR02480
866346001337	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
866346001338	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4731
866346001339	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
866346001340	metal binding site 2 [ion binding]; metal-binding site
866346001341	putative DNA binding helix; other site
866346001342	metal binding site 1 [ion binding]; metal-binding site
866346001343	dimer interface [polypeptide binding]; other site
866346001344	structural Zn2+ binding site [ion binding]; other site
866346001345	ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; Region: MGS1; COG2256
866346001346	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346001347	Walker A motif; other site
866346001348	ATP binding site [chemical binding]; other site
866346001349	Walker B motif; other site
866346001350	arginine finger; other site
866346001351	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
866346001352	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
866346001353	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
866346001354	DNA binding residues [nucleotide binding]
866346001355	putative dimer interface [polypeptide binding]; other site
866346001356	chaperone protein DnaJ; Provisional; Region: PRK14299
866346001357	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
866346001358	HSP70 interaction site [polypeptide binding]; other site
866346001359	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
866346001360	substrate binding site [polypeptide binding]; other site
866346001361	dimer interface [polypeptide binding]; other site
866346001362	5'-3' exonuclease; Provisional; Region: PRK14976
866346001363	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
866346001364	putative active site [active]
866346001365	Helix-hairpin-helix class 2 (Pol1 family) motifs; Region: HhH2; smart00279
866346001366	DNA binding site [nucleotide binding]
866346001367	metal binding site [ion binding]; metal-binding site
866346001368	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
866346001369	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866346001370	active site
866346001371	intermolecular recognition site; other site
866346001372	dimerization interface [polypeptide binding]; other site
866346001373	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
866346001374	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
866346001375	substrate binding site; other site
866346001376	dimer interface; other site
866346001377	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
866346001378	homotrimer interaction site [polypeptide binding]; other site
866346001379	zinc binding site [ion binding]; other site
866346001380	CDP-binding sites; other site
866346001381	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
866346001382	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
866346001383	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
866346001384	protein binding site [polypeptide binding]; other site
866346001385	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
866346001386	protein binding site [polypeptide binding]; other site
866346001387	S-methylmethionine transporter; Provisional; Region: PRK11387
866346001388	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Region: pgsA; TIGR00560
866346001389	7-alpha-hydroxysteroid dehydrogenase; Provisional; Region: PRK08416
866346001390	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
866346001391	putative NAD(P) binding site [chemical binding]; other site
866346001392	active site
866346001393	dihydrodipicolinate synthase; Region: dapA; TIGR00674
866346001394	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
866346001395	dimer interface [polypeptide binding]; other site
866346001396	active site
866346001397	catalytic residue [active]
866346001398	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
866346001399	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
866346001400	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
866346001401	dihydroorotate dehydrogenase, subfamily 2; Region: pyrD_sub2; TIGR01036
866346001402	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
866346001403	quinone interaction residues [chemical binding]; other site
866346001404	active site
866346001405	catalytic residues [active]
866346001406	FMN binding site [chemical binding]; other site
866346001407	substrate binding site [chemical binding]; other site
866346001408	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
866346001409	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
866346001410	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
866346001411	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
866346001412	putative domain interface [polypeptide binding]; other site
866346001413	putative active site [active]
866346001414	catalytic site [active]
866346001415	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
866346001416	putative active site [active]
866346001417	putative domain interface [polypeptide binding]; other site
866346001418	catalytic site [active]
866346001419	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866346001420	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
866346001421	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866346001422	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
866346001423	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
866346001424	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
866346001425	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
866346001426	ATP binding site [chemical binding]; other site
866346001427	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
866346001428	putative Mg++ binding site [ion binding]; other site
866346001429	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
866346001430	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
866346001431	putative metal binding site [ion binding]; other site
866346001432	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
866346001433	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
866346001434	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
866346001435	active site
866346001436	Zn binding site [ion binding]; other site
866346001437	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
866346001438	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
866346001439	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346001440	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
866346001441	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
866346001442	potential frameshift: common BLAST hit: gi|188527260|ref|YP_001909947.1| molybdenum ABC transporter ModB
866346001443	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
866346001444	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866346001445	ABC-ATPase subunit interface; other site
866346001446	putative PBP binding loops; other site
866346001447	potential frameshift: common BLAST hit: gi|188527261|ref|YP_001909948.1| molybdenum ABC transporter ModD
866346001448	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866346001449	Walker A/P-loop; other site
866346001450	ATP binding site [chemical binding]; other site
866346001451	Q-loop/lid; other site
866346001452	ABC transporter signature motif; other site
866346001453	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866346001454	Walker B; other site
866346001455	D-loop; other site
866346001456	H-loop/switch region; other site
866346001457	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
866346001458	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
866346001459	active site
866346001460	HIGH motif; other site
866346001461	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
866346001462	active site
866346001463	KMSKS motif; other site
866346001464	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346001465	Helix-turn-helix domain; Region: HTH_17; pfam12728
866346001466	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
866346001467	Methyltransferase domain; Region: Methyltransf_26; pfam13659
866346001468	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
866346001469	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
866346001470	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
866346001471	ADP-heptose:LPS heptosyl transferase I; Provisional; Region: PRK10964; cl15782
866346001472	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
866346001473	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
866346001474	G1 box; other site
866346001475	putative GEF interaction site [polypeptide binding]; other site
866346001476	GTP/Mg2+ binding site [chemical binding]; other site
866346001477	Switch I region; other site
866346001478	G2 box; other site
866346001479	G3 box; other site
866346001480	Switch II region; other site
866346001481	G4 box; other site
866346001482	G5 box; other site
866346001483	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
866346001484	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
866346001485	potential frameshift: common BLAST hit: gi|308182629|ref|YP_003926756.1| type II adenine specific DNA methyltransferase
866346001486	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
866346001487	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
866346001488	Catalytic GIY-YIG domain of coliphage T4 non-specific endonuclease II, type II restriction endonuclease R.Hpy188I, and similar proteins; Region: GIY-YIG_EndoII_Hpy188I_like; cd10436
866346001489	GIY-YIG motif/motif A; other site
866346001490	DNA binding site [nucleotide binding]
866346001491	active site
866346001492	catalytic site [active]
866346001493	metal binding site [ion binding]; metal-binding site
866346001494	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
866346001495	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
866346001496	cofactor binding site; other site
866346001497	DNA binding site [nucleotide binding]
866346001498	substrate interaction site [chemical binding]; other site
866346001499	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
866346001500	potential frameshift: common BLAST hit: gi|254779149|ref|YP_003057254.1| non-functional type II restriction endonuclease
866346001501	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
866346001502	Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153
866346001503	putative heme binding pocket [chemical binding]; other site
866346001504	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866346001505	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866346001506	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
866346001507	Protein of unknown function (DUF3519); Region: DUF3519; pfam12033
866346001508	Cation transport protein; Region: TrkH; cl17365
866346001509	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
866346001510	TrkA-N domain; Region: TrkA_N; pfam02254
866346001511	TrkA-C domain; Region: TrkA_C; pfam02080
866346001512	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
866346001513	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
866346001514	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
866346001515	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
866346001516	Mg++ binding site [ion binding]; other site
866346001517	putative catalytic motif [active]
866346001518	putative substrate binding site [chemical binding]; other site
866346001519	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03815
866346001520	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866346001521	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866346001522	Protein of unknown function (DUF493); Region: DUF493; pfam04359
866346001523	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
866346001524	active site
866346001525	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
866346001526	Na2 binding site [ion binding]; other site
866346001527	putative substrate binding site 1 [chemical binding]; other site
866346001528	Na binding site 1 [ion binding]; other site
866346001529	putative substrate binding site 2 [chemical binding]; other site
866346001530	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
866346001531	Na2 binding site [ion binding]; other site
866346001532	putative substrate binding site 1 [chemical binding]; other site
866346001533	Na binding site 1 [ion binding]; other site
866346001534	putative substrate binding site 2 [chemical binding]; other site
866346001535	potential frameshift: common BLAST hit: gi|308184280|ref|YP_003928413.1| phospholipase A1
866346001536	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cl00248
866346001537	dimerization interface [polypeptide binding]; other site
866346001538	substrate binding site [chemical binding]; other site
866346001539	active site
866346001540	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cl00248
866346001541	DNA polymerase III, beta subunit; Region: dnan; TIGR00663
866346001542	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
866346001543	putative DNA binding surface [nucleotide binding]; other site
866346001544	dimer interface [polypeptide binding]; other site
866346001545	beta-clamp/translesion DNA polymerase binding surface; other site
866346001546	beta-clamp/clamp loader binding surface; other site
866346001547	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
866346001548	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866346001549	Mg2+ binding site [ion binding]; other site
866346001550	G-X-G motif; other site
866346001551	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
866346001552	anchoring element; other site
866346001553	dimer interface [polypeptide binding]; other site
866346001554	ATP binding site [chemical binding]; other site
866346001555	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
866346001556	active site
866346001557	putative metal-binding site [ion binding]; other site
866346001558	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
866346001559	R.Pab1 restriction endonuclease; Region: RE_R_Pab1; pfam09522
866346001560	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
866346001561	Peptidase family M23; Region: Peptidase_M23; pfam01551
866346001562	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
866346001563	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
866346001564	dimer interface [polypeptide binding]; other site
866346001565	ADP-ribose binding site [chemical binding]; other site
866346001566	active site
866346001567	nudix motif; other site
866346001568	metal binding site [ion binding]; metal-binding site
866346001569	FAD binding domain; Region: FAD_binding_4; pfam01565
866346001570	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
866346001571	Protein-interacting Bro1-like domain of mammalian Alix and related domains; Region: BRO1_Alix_like; cl14649
866346001572	dihydrodipicolinate reductase; Region: dapB; TIGR00036
866346001573	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
866346001574	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
866346001575	glutamine synthetase, type I; Region: GlnA; TIGR00653
866346001576	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
866346001577	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
866346001578	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
866346001579	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866346001580	Protein of unknown function DUF262; Region: DUF262; pfam03235
866346001581	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866346001582	Uncharacterized conserved protein [Function unknown]; Region: COG3586
866346001583	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
866346001584	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
866346001585	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
866346001586	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
866346001587	active site
866346001588	HslU subunit interaction site [polypeptide binding]; other site
866346001589	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
866346001590	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346001591	Walker A motif; other site
866346001592	ATP binding site [chemical binding]; other site
866346001593	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346001594	Walker B motif; other site
866346001595	arginine finger; other site
866346001596	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
866346001597	GTPase Era; Reviewed; Region: era; PRK00089
866346001598	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
866346001599	G1 box; other site
866346001600	GTP/Mg2+ binding site [chemical binding]; other site
866346001601	Switch I region; other site
866346001602	G2 box; other site
866346001603	Switch II region; other site
866346001604	G3 box; other site
866346001605	G4 box; other site
866346001606	G5 box; other site
866346001607	KH domain; Region: KH_2; pfam07650
866346001608	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
866346001609	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866346001610	Sel1 repeat; Region: Sel1; cl02723
866346001611	Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion]; Region: VirD4; COG3505
866346001612	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
866346001613	Walker A motif; other site
866346001614	ATP binding site [chemical binding]; other site
866346001615	Walker B motif; other site
866346001616	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
866346001617	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
866346001618	ATP binding site [chemical binding]; other site
866346001619	Walker A motif; other site
866346001620	hexamer interface [polypeptide binding]; other site
866346001621	Walker B motif; other site
866346001622	CagZ; Region: CagZ; pfam09053
866346001623	DC-EC Repeat; Region: CagY_M; pfam07337
866346001624	DC-EC Repeat; Region: CagY_M; pfam07337
866346001625	DC-EC Repeat; Region: CagY_M; pfam07337
866346001626	DC-EC Repeat; Region: CagY_M; pfam07337
866346001627	DC-EC Repeat; Region: CagY_M; pfam07337
866346001628	DC-EC Repeat; Region: CagY_M; pfam07337
866346001629	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
866346001630	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
866346001631	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
866346001632	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
866346001633	VirB7 interaction site; other site
866346001634	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
866346001635	Cag pathogenicity island protein Cag12; Region: Cag12; pfam13117
866346001636	prolyl-tRNA synthetase; Provisional; Region: PRK08661
866346001637	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
866346001638	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
866346001639	CagA exotoxin; Region: CagA; pfam03507
866346001640	CagA exotoxin; Region: CagA; pfam03507
866346001641	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
866346001642	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
866346001643	transcription termination factor Rho; Provisional; Region: rho; PRK09376
866346001644	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
866346001645	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
866346001646	RNA binding site [nucleotide binding]; other site
866346001647	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
866346001648	multimer interface [polypeptide binding]; other site
866346001649	Walker A motif; other site
866346001650	ATP binding site [chemical binding]; other site
866346001651	Walker B motif; other site
866346001652	Ribosomal protein L31; Region: Ribosomal_L31; pfam01197
866346001653	Predicted methyltransferases [General function prediction only]; Region: COG0313
866346001654	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
866346001655	putative SAM binding site [chemical binding]; other site
866346001656	putative homodimer interface [polypeptide binding]; other site
866346001657	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
866346001658	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
866346001659	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
866346001660	acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Region: accA; TIGR00513
866346001661	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
866346001662	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK08439
866346001663	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
866346001664	dimer interface [polypeptide binding]; other site
866346001665	active site
866346001666	acyl carrier protein; Provisional; Region: acpP; PRK00982
866346001667	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
866346001668	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
866346001669	NAD(P) binding site [chemical binding]; other site
866346001670	active site
866346001671	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
866346001672	Predicted membrane protein [Function unknown]; Region: COG3059
866346001673	diaminopimelate epimerase; Region: DapF; TIGR00652
866346001674	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
866346001675	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
866346001676	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
866346001677	Domain of unknown function DUF20; Region: UPF0118; pfam01594
866346001678	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866346001679	FeS/SAM binding site; other site
866346001680	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
866346001681	GTP-binding protein YchF; Reviewed; Region: PRK09601
866346001682	YchF GTPase; Region: YchF; cd01900
866346001683	G1 box; other site
866346001684	GTP/Mg2+ binding site [chemical binding]; other site
866346001685	Switch I region; other site
866346001686	G2 box; other site
866346001687	Switch II region; other site
866346001688	G3 box; other site
866346001689	G4 box; other site
866346001690	G5 box; other site
866346001691	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
866346001692	multifunctional aminopeptidase A; Provisional; Region: PRK00913
866346001693	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
866346001694	interface (dimer of trimers) [polypeptide binding]; other site
866346001695	Substrate-binding/catalytic site; other site
866346001696	Zn-binding sites [ion binding]; other site
866346001697	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
866346001698	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866346001699	active site
866346001700	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
866346001701	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
866346001702	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
866346001703	Peptidase family M50; Region: Peptidase_M50; pfam02163
866346001704	active site
866346001705	putative substrate binding region [chemical binding]; other site
866346001706	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
866346001707	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
866346001708	Catalytic site [active]
866346001709	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
866346001710	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14191
866346001711	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
866346001712	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
866346001713	homodimer interface [polypeptide binding]; other site
866346001714	NADP binding site [chemical binding]; other site
866346001715	substrate binding site [chemical binding]; other site
866346001716	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
866346001717	Sulfatase; Region: Sulfatase; pfam00884
866346001718	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
866346001719	BNR repeat-like domain; Region: BNR_2; pfam13088
866346001720	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
866346001721	active site
866346001722	substrate binding pocket [chemical binding]; other site
866346001723	dimer interface [polypeptide binding]; other site
866346001724	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
866346001725	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
866346001726	flagellar motor switch protein; Validated; Region: PRK08433
866346001727	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
866346001728	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
866346001729	minor groove reading motif; other site
866346001730	helix-hairpin-helix signature motif; other site
866346001731	substrate binding pocket [chemical binding]; other site
866346001732	active site
866346001733	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
866346001734	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
866346001735	Protein of unknown function; Region: DUF3971; pfam13116
866346001736	AsmA-like C-terminal region; Region: AsmA_1; pfam13109
866346001737	YceG-like family; Region: YceG; pfam02618
866346001738	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
866346001739	dimerization interface [polypeptide binding]; other site
866346001740	2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed; Region: oorD; PRK09626
866346001741	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
866346001742	2-oxoglutarate-acceptor oxidoreductase subunit OorA; Reviewed; Region: oorA; PRK09627
866346001743	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
866346001744	dimer interface [polypeptide binding]; other site
866346001745	PYR/PP interface [polypeptide binding]; other site
866346001746	TPP binding site [chemical binding]; other site
866346001747	substrate binding site [chemical binding]; other site
866346001748	2-oxoglutarate-acceptor oxidoreductase subunit OorB; Reviewed; Region: oorB; PRK09628
866346001749	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
866346001750	TPP-binding site [chemical binding]; other site
866346001751	2-oxoglutarate-acceptor oxidoreductase subunit OorC; Reviewed; Region: oorC; PRK08441
866346001752	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
866346001753	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
866346001754	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Region: HAD-SF-IA-v1; TIGR01549
866346001755	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
866346001756	tumor necrosis factor alpha-inducing protein; Reviewed; Region: PRK12303
866346001757	Transglycosylase; Region: Transgly; pfam00912
866346001758	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
866346001759	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
866346001760	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
866346001761	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
866346001762	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866346001763	catalytic residue [active]
866346001764	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
866346001765	dimer interface [polypeptide binding]; other site
866346001766	putative CheW interface [polypeptide binding]; other site
866346001767	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
866346001768	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
866346001769	ABC transporter; Region: ABC_tran; pfam00005
866346001770	Q-loop/lid; other site
866346001771	ABC transporter signature motif; other site
866346001772	Walker B; other site
866346001773	D-loop; other site
866346001774	H-loop/switch region; other site
866346001775	flagellin A; Reviewed; Region: PRK12584
866346001776	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
866346001777	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
866346001778	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
866346001779	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
866346001780	3-methyladenine DNA glycosylase; Provisional; Region: PRK13913
866346001781	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
866346001782	minor groove reading motif; other site
866346001783	helix-hairpin-helix signature motif; other site
866346001784	active site
866346001785	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
866346001786	substrate binding site [chemical binding]; other site
866346001787	active site
866346001788	Outer membrane efflux protein; Region: OEP; pfam02321
866346001789	Outer membrane efflux protein; Region: OEP; pfam02321
866346001790	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866346001791	HlyD family secretion protein; Region: HlyD_3; pfam13437
866346001792	AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873
866346001793	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346001794	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
866346001795	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866346001796	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866346001797	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866346001798	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866346001799	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
866346001800	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866346001801	Autotransporter beta-domain; Region: Autotransporter; pfam03797
866346001802	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866346001803	ABC transporter signature motif; other site
866346001804	Walker B; other site
866346001805	D-loop; other site
866346001806	H-loop/switch region; other site
866346001807	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
866346001808	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
866346001809	nucleotide binding pocket [chemical binding]; other site
866346001810	K-X-D-G motif; other site
866346001811	catalytic site [active]
866346001812	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
866346001813	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
866346001814	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
866346001815	Dimer interface [polypeptide binding]; other site
866346001816	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
866346001817	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
866346001818	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866346001819	active site
866346001820	phosphorylation site [posttranslational modification]
866346001821	intermolecular recognition site; other site
866346001822	dimerization interface [polypeptide binding]; other site
866346001823	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
866346001824	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
866346001825	dimer interface [polypeptide binding]; other site
866346001826	anticodon binding site; other site
866346001827	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
866346001828	homodimer interface [polypeptide binding]; other site
866346001829	motif 1; other site
866346001830	active site
866346001831	motif 2; other site
866346001832	GAD domain; Region: GAD; pfam02938
866346001833	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
866346001834	active site
866346001835	motif 3; other site
866346001836	adenylate kinase; Reviewed; Region: adk; PRK00279
866346001837	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
866346001838	AMP-binding site [chemical binding]; other site
866346001839	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
866346001840	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
866346001841	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
866346001842	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
866346001843	Glycosyltransferase involved in LPS biosynthesis [Cell envelope biogenesis, outer membrane]; Region: COG3306
866346001844	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
866346001845	dimer interface [polypeptide binding]; other site
866346001846	substrate binding site [chemical binding]; other site
866346001847	metal binding sites [ion binding]; metal-binding site
866346001848	MutS2 family protein; Region: mutS2; TIGR01069
866346001849	ATPase domain of DNA mismatch repair MUTS family; Region: MUTSac; smart00534
866346001850	Walker A/P-loop; other site
866346001851	ATP binding site [chemical binding]; other site
866346001852	Q-loop/lid; other site
866346001853	ABC transporter signature motif; other site
866346001854	Walker B; other site
866346001855	D-loop; other site
866346001856	H-loop/switch region; other site
866346001857	Smr domain; Region: Smr; pfam01713
866346001858	UDP-N-acetylmuramate--alanine ligase; Region: murC; TIGR01082
866346001859	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
866346001860	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866346001861	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866346001862	hypothetical protein; Provisional; Region: PRK05839
866346001863	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
866346001864	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866346001865	homodimer interface [polypeptide binding]; other site
866346001866	catalytic residue [active]
866346001867	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
866346001868	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
866346001869	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
866346001870	Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Region: DapD; COG2171
866346001871	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
866346001872	putative trimer interface [polypeptide binding]; other site
866346001873	putative CoA binding site [chemical binding]; other site
866346001874	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866346001875	Sel1-like repeats; Region: SEL1; smart00671
866346001876	Sel1-like repeats; Region: SEL1; smart00671
866346001877	Sel1 repeat; Region: Sel1; cl02723
866346001878	Sel1-like repeats; Region: SEL1; smart00671
866346001879	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866346001880	Protein of unknown function DUF262; Region: DUF262; pfam03235
866346001881	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866346001882	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
866346001883	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
866346001884	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
866346001885	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
866346001886	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
866346001887	Ni/Fe-hydrogenase, b-type cytochrome subunit; Region: CytB-hydogenase; TIGR02125
866346001888	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
866346001889	nickel binding site [ion binding]; other site
866346001890	putative substrate-binding site; other site
866346001891	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346001892	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
866346001893	Ligand Binding Site [chemical binding]; other site
866346001894	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
866346001895	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
866346001896	active site
866346001897	NTP binding site [chemical binding]; other site
866346001898	metal binding triad [ion binding]; metal-binding site
866346001899	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
866346001900	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
866346001901	dimer interface [polypeptide binding]; other site
866346001902	FMN binding site [chemical binding]; other site
866346001903	glutamylglutaminyl-tRNA synthetase; Provisional; Region: PRK12410
866346001904	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
866346001905	active site
866346001906	HIGH motif; other site
866346001907	nucleotide binding site [chemical binding]; other site
866346001908	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
866346001909	active site
866346001910	KMSKS motif; other site
866346001911	YGGT family; Region: YGGT; pfam02325
866346001912	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
866346001913	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
866346001914	N-acetyl-D-glucosamine binding site [chemical binding]; other site
866346001915	catalytic residue [active]
866346001916	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
866346001917	active site
866346001918	tetramer interface; other site
866346001919	sensor protein RstB; Provisional; Region: PRK10604
866346001920	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
866346001921	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
866346001922	hinge; other site
866346001923	active site
866346001924	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
866346001925	Aspartase; Region: Aspartase; cd01357
866346001926	active sites [active]
866346001927	tetramer interface [polypeptide binding]; other site
866346001928	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
866346001929	ligand binding site [chemical binding]; other site
866346001930	active site
866346001931	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
866346001932	phosphoserine phosphatase SerB; Region: serB; TIGR00338
866346001933	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866346001934	motif II; other site
866346001935	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
866346001936	Ferritin-like domain; Region: Ferritin; pfam00210
866346001937	ferroxidase diiron center [ion binding]; other site
866346001938	hypothetical protein; Provisional; Region: PRK08444
866346001939	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866346001940	FeS/SAM binding site; other site
866346001941	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
866346001942	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866346001943	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866346001944	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866346001945	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866346001946	Surface antigen; Region: Bac_surface_Ag; pfam01103
866346001947	hypothetical protein; Provisional; Region: PRK08445
866346001948	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866346001949	FeS/SAM binding site; other site
866346001950	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
866346001951	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
866346001952	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
866346001953	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
866346001954	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
866346001955	GatB domain; Region: GatB_Yqey; smart00845
866346001956	SurA N-terminal domain; Region: SurA_N; pfam09312
866346001957	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
866346001958	Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module [General function prediction only]; Region: COG1439
866346001959	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
866346001960	RNA/DNA hybrid binding site [nucleotide binding]; other site
866346001961	active site
866346001962	ribonuclease III; Reviewed; Region: rnc; PRK00102
866346001963	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
866346001964	dimerization interface [polypeptide binding]; other site
866346001965	active site
866346001966	metal binding site [ion binding]; metal-binding site
866346001967	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
866346001968	dsRNA binding site [nucleotide binding]; other site
866346001969	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
866346001970	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
866346001971	Tetramer interface [polypeptide binding]; other site
866346001972	active site
866346001973	FMN-binding site [chemical binding]; other site
866346001974	Protein of unknown function (DUF2603); Region: DUF2603; pfam10788
866346001975	oxygen-independent coproporphyrinogen III oxidase; Region: hemN; TIGR00538
866346001976	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866346001977	FeS/SAM binding site; other site
866346001978	HemN C-terminal domain; Region: HemN_C; pfam06969
866346001979	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
866346001980	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866346001981	Cysteine-rich domain; Region: CCG; pfam02754
866346001982	Cysteine-rich domain; Region: CCG; pfam02754
866346001983	potential frameshift: common BLAST hit: gi|210134874|ref|YP_002301313.1| type II R-M system protein
866346001984	Restriction endonuclease; Region: Mrr_cat_2; pfam13156
866346001985	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866346001986	ATP binding site [chemical binding]; other site
866346001987	putative Mg++ binding site [ion binding]; other site
866346001988	Predicted helicase [General function prediction only]; Region: COG4889
866346001989	Predicted helicase [General function prediction only]; Region: COG4889
866346001990	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
866346001991	ATP-binding site [chemical binding]; other site
866346001992	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346001993	aspartate aminotransferase; Provisional; Region: PRK05764
866346001994	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
866346001995	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866346001996	homodimer interface [polypeptide binding]; other site
866346001997	catalytic residue [active]
866346001998	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
866346001999	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
866346002000	active site
866346002001	DNA binding site [nucleotide binding]
866346002002	Int/Topo IB signature motif; other site
866346002003	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
866346002004	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
866346002005	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
866346002006	DNA binding site [nucleotide binding]
866346002007	active site
866346002008	potential frameshift: common BLAST hit: gi|210134883|ref|YP_002301322.1| integral membrane protein
866346002009	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
866346002010	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
866346002011	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
866346002012	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
866346002013	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08447
866346002014	ATP cone domain; Region: ATP-cone; pfam03477
866346002015	Class I ribonucleotide reductase; Region: RNR_I; cd01679
866346002016	active site
866346002017	dimer interface [polypeptide binding]; other site
866346002018	catalytic residues [active]
866346002019	effector binding site; other site
866346002020	R2 peptide binding site; other site
866346002021	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14359
866346002022	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
866346002023	Substrate binding site; other site
866346002024	Mg++ binding site; other site
866346002025	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
866346002026	active site
866346002027	substrate binding site [chemical binding]; other site
866346002028	CoA binding site [chemical binding]; other site
866346002029	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
866346002030	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
866346002031	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
866346002032	N-terminal plug; other site
866346002033	ligand-binding site [chemical binding]; other site
866346002034	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
866346002035	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
866346002036	G1 box; other site
866346002037	GTP/Mg2+ binding site [chemical binding]; other site
866346002038	Switch I region; other site
866346002039	G2 box; other site
866346002040	G3 box; other site
866346002041	Switch II region; other site
866346002042	G4 box; other site
866346002043	G5 box; other site
866346002044	Nucleoside recognition; Region: Gate; pfam07670
866346002045	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
866346002046	Nucleoside recognition; Region: Gate; pfam07670
866346002047	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
866346002048	active site
866346002049	catalytic site [active]
866346002050	substrate binding site [chemical binding]; other site
866346002051	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108
866346002052	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
866346002053	cofactor binding site; other site
866346002054	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
866346002055	DNA binding site [nucleotide binding]
866346002056	substrate interaction site [chemical binding]; other site
866346002057	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
866346002058	potential frameshift: common BLAST hit: gi|269123999|ref|YP_003306576.1| type II site-specific deoxyribonuclease
866346002059	NgoBV restriction endonuclease; Region: RE_NgoBV; pfam09564
866346002060	NgoBV restriction endonuclease; Region: RE_NgoBV; pfam09564
866346002061	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB [DNA replication, recombination, and repair]; Region: COG3298
866346002062	putative acyltransferase; Provisional; Region: PRK05790
866346002063	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
866346002064	dimer interface [polypeptide binding]; other site
866346002065	active site
866346002066	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
866346002067	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
866346002068	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
866346002069	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
866346002070	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
866346002071	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
866346002072	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
866346002073	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
866346002074	Hydantoinase B/oxoprolinase; Region: Hydantoinase_B; pfam02538
866346002075	Acetone carboxylase, gamma subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcxC; COG4647
866346002076	Acetone carboxylase gamma subunit; Region: Acetone_carb_G; pfam08882
866346002077	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
866346002078	DNA gyrase subunit A; Validated; Region: PRK05560
866346002079	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
866346002080	CAP-like domain; other site
866346002081	active site
866346002082	primary dimer interface [polypeptide binding]; other site
866346002083	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866346002084	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866346002085	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866346002086	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866346002087	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866346002088	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866346002089	Response regulator receiver domain; Region: Response_reg; pfam00072
866346002090	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866346002091	active site
866346002092	phosphorylation site [posttranslational modification]
866346002093	intermolecular recognition site; other site
866346002094	dimerization interface [polypeptide binding]; other site
866346002095	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346002096	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
866346002097	Walker A motif; other site
866346002098	ATP binding site [chemical binding]; other site
866346002099	Walker B motif; other site
866346002100	arginine finger; other site
866346002101	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
866346002102	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
866346002103	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
866346002104	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
866346002105	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346002106	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
866346002107	MraW methylase family; Region: Methyltransf_5; cl17771
866346002108	Uncharacterized conserved protein [Function unknown]; Region: COG1912
866346002109	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
866346002110	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
866346002111	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346002112	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
866346002113	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
866346002114	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
866346002115	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
866346002116	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
866346002117	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
866346002118	Walker A/P-loop; other site
866346002119	ATP binding site [chemical binding]; other site
866346002120	Q-loop/lid; other site
866346002121	ABC transporter signature motif; other site
866346002122	Walker B; other site
866346002123	D-loop; other site
866346002124	H-loop/switch region; other site
866346002125	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
866346002126	DNA polymerase III subunits gamma and tau; Validated; Region: PRK08451
866346002127	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346002128	Walker A motif; other site
866346002129	ATP binding site [chemical binding]; other site
866346002130	Walker B motif; other site
866346002131	arginine finger; other site
866346002132	Lysine efflux permease [General function prediction only]; Region: COG1279
866346002133	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
866346002134	Protein of unknown function (DUF1104); Region: DUF1104; pfam06518
866346002135	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
866346002136	active site
866346002137	homodimer interface [polypeptide binding]; other site
866346002138	homotetramer interface [polypeptide binding]; other site
866346002139	Anaerobic c4-dicarboxylate membrane transporter; Region: DcuA_DcuB; cl01040
866346002140	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
866346002141	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346002142	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
866346002143	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
866346002144	FMN binding site [chemical binding]; other site
866346002145	active site
866346002146	catalytic residues [active]
866346002147	substrate binding site [chemical binding]; other site
866346002148	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
866346002149	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
866346002150	Ligand Binding Site [chemical binding]; other site
866346002151	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
866346002152	G1 box; other site
866346002153	GTP/Mg2+ binding site [chemical binding]; other site
866346002154	G2 box; other site
866346002155	Switch I region; other site
866346002156	G3 box; other site
866346002157	Switch II region; other site
866346002158	G4 box; other site
866346002159	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
866346002160	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
866346002161	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866346002162	FeS/SAM binding site; other site
866346002163	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236
866346002164	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866346002165	active site
866346002166	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
866346002167	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866346002168	catalytic residue [active]
866346002169	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
866346002170	tetramer interfaces [polypeptide binding]; other site
866346002171	binuclear metal-binding site [ion binding]; other site
866346002172	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
866346002173	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
866346002174	ATP-grasp domain; Region: ATP-grasp_4; cl17255
866346002175	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
866346002176	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
866346002177	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866346002178	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
866346002179	nucleotide binding site/active site [active]
866346002180	HIT family signature motif; other site
866346002181	catalytic residue [active]
866346002182	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
866346002183	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
866346002184	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866346002185	active site
866346002186	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
866346002187	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
866346002188	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
866346002189	Predicted GTPase [General function prediction only]; Region: COG3596
866346002190	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
866346002191	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
866346002192	G1 box; other site
866346002193	G1 box; other site
866346002194	GTP/Mg2+ binding site [chemical binding]; other site
866346002195	GTP/Mg2+ binding site [chemical binding]; other site
866346002196	G2 box; other site
866346002197	Switch I region; other site
866346002198	G3 box; other site
866346002199	Switch II region; other site
866346002200	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
866346002201	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
866346002202	active site
866346002203	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
866346002204	Interdomain contacts; other site
866346002205	Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401
866346002206	Cytokine receptor motif; other site
866346002207	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
866346002208	Interdomain contacts; other site
866346002209	Cytokine receptor motif; other site
866346002210	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
866346002211	Interdomain contacts; other site
866346002212	Cytokine receptor motif; other site
866346002213	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866346002214	S-adenosylmethionine binding site [chemical binding]; other site
866346002215	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
866346002216	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
866346002217	Walker A/P-loop; other site
866346002218	ATP binding site [chemical binding]; other site
866346002219	Q-loop/lid; other site
866346002220	ABC transporter signature motif; other site
866346002221	Walker B; other site
866346002222	D-loop; other site
866346002223	H-loop/switch region; other site
866346002224	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
866346002225	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
866346002226	Peptidase family M23; Region: Peptidase_M23; pfam01551
866346002227	flagellar protein FlaG; Provisional; Region: PRK08452
866346002228	flagellar capping protein; Validated; Region: fliD; PRK08453
866346002229	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
866346002230	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
866346002231	flagellar biosynthetic protein FliS; Region: fliS; TIGR00208
866346002232	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
866346002233	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
866346002234	putative ATP binding site [chemical binding]; other site
866346002235	putative substrate interface [chemical binding]; other site
866346002236	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
866346002237	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
866346002238	putative active site; other site
866346002239	catalytic triad [active]
866346002240	putative dimer interface [polypeptide binding]; other site
866346002241	Predicted permease [General function prediction only]; Region: COG2056
866346002242	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
866346002243	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
866346002244	putative efflux protein, MATE family; Region: matE; TIGR00797
866346002245	phosphodiesterase; Provisional; Region: PRK12704
866346002246	K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; Region: KH-I; cd00105
866346002247	nucleic acid binding region [nucleotide binding]; other site
866346002248	G-X-X-G motif; other site
866346002249	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
866346002250	Zn2+ binding site [ion binding]; other site
866346002251	Mg2+ binding site [ion binding]; other site
866346002252	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
866346002253	signal recognition particle-docking protein FtsY; Region: ftsY; TIGR00064
866346002254	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
866346002255	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
866346002256	Mu-like prophage protein [General function prediction only]; Region: COG3941
866346002257	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
866346002258	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866346002259	FeS/SAM binding site; other site
866346002260	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
866346002261	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
866346002262	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
866346002263	GTP binding site; other site
866346002264	flagellar biosynthetic protein FlhB; Region: flhB; TIGR00328
866346002265	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
866346002266	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
866346002267	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
866346002268	active site
866346002269	metal binding site [ion binding]; metal-binding site
866346002270	Nitronate monooxygenase; Region: NMO; pfam03060
866346002271	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
866346002272	FMN binding site [chemical binding]; other site
866346002273	substrate binding site [chemical binding]; other site
866346002274	putative catalytic residue [active]
866346002275	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
866346002276	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
866346002277	active site
866346002278	HIGH motif; other site
866346002279	dimer interface [polypeptide binding]; other site
866346002280	KMSKS motif; other site
866346002281	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866346002282	RNA binding surface [nucleotide binding]; other site
866346002283	(p)ppGpp synthetase, RelA/SpoT family; Region: spoT_relA; TIGR00691
866346002284	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
866346002285	Zn2+ binding site [ion binding]; other site
866346002286	Mg2+ binding site [ion binding]; other site
866346002287	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
866346002288	synthetase active site [active]
866346002289	NTP binding site [chemical binding]; other site
866346002290	metal binding site [ion binding]; metal-binding site
866346002291	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
866346002292	DNA-directed RNA polymerase, subunit K/omega [Transcription]; Region: RpoZ; COG1758
866346002293	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
866346002294	putative nucleotide binding site [chemical binding]; other site
866346002295	uridine monophosphate binding site [chemical binding]; other site
866346002296	homohexameric interface [polypeptide binding]; other site
866346002297	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG1427
866346002298	aconitate hydratase 2; Region: acnB; TIGR00117
866346002299	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
866346002300	substrate binding site [chemical binding]; other site
866346002301	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
866346002302	substrate binding site [chemical binding]; other site
866346002303	ligand binding site [chemical binding]; other site
866346002304	FOG: Transposase [DNA replication, recombination, and repair]; Region: COG5659
866346002305	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866346002306	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
866346002307	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
866346002308	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
866346002309	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
866346002310	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866346002311	nucleotide binding region [chemical binding]; other site
866346002312	ATP-binding site [chemical binding]; other site
866346002313	SEC-C motif; Region: SEC-C; pfam02810
866346002314	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
866346002315	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
866346002316	FtsX-like permease family; Region: FtsX; pfam02687
866346002317	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866346002318	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866346002319	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
866346002320	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866346002321	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207
866346002322	metal-binding site [ion binding]
866346002323	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
866346002324	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
866346002325	Soluble P-type ATPase [General function prediction only]; Region: COG4087
866346002326	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
866346002327	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
866346002328	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
866346002329	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
866346002330	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
866346002331	active site
866346002332	catalytic residues [active]
866346002333	metal binding site [ion binding]; metal-binding site
866346002334	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
866346002335	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
866346002336	oligomer interface [polypeptide binding]; other site
866346002337	active site residues [active]
866346002338	trigger factor; Provisional; Region: tig; PRK01490
866346002339	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
866346002340	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
866346002341	potential frameshift: common BLAST hit: gi|188527360|ref|YP_001910047.1| outer membrane protein
866346002342	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346002343	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346002344	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
866346002345	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
866346002346	trimer interface [polypeptide binding]; other site
866346002347	dimer interface [polypeptide binding]; other site
866346002348	putative active site [active]
866346002349	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
866346002350	MPT binding site; other site
866346002351	trimer interface [polypeptide binding]; other site
866346002352	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
866346002353	MoaE homodimer interface [polypeptide binding]; other site
866346002354	MoaD interaction [polypeptide binding]; other site
866346002355	active site residues [active]
866346002356	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
866346002357	MoaE interaction surface [polypeptide binding]; other site
866346002358	MoeB interaction surface [polypeptide binding]; other site
866346002359	thiocarboxylated glycine; other site
866346002360	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
866346002361	dimerization interface [polypeptide binding]; other site
866346002362	active site
866346002363	Domain of unknown function (DUF3943); Region: DUF3943; pfam13084
866346002364	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09314
866346002365	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: ribB; TIGR00506
866346002366	GTP cyclohydrolase II [Coenzyme metabolism]; Region: RibA; COG0807
866346002367	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
866346002368	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
866346002369	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
866346002370	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
866346002371	N-terminal plug; other site
866346002372	ligand-binding site [chemical binding]; other site
866346002373	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
866346002374	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK08455
866346002375	RNA methyltransferase, RsmD family; Region: TIGR00095
866346002376	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
866346002377	Uncharacterized conserved protein [Function unknown]; Region: COG1565
866346002378	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
866346002379	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Region: ThiF; COG0476
866346002380	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
866346002381	ATP binding site [chemical binding]; other site
866346002382	substrate interface [chemical binding]; other site
866346002383	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
866346002384	flagellar motor protein MotA; Validated; Region: PRK08456
866346002385	flagellar motor protein MotB; Reviewed; Region: motB; PRK08457
866346002386	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
866346002387	ligand binding site [chemical binding]; other site
866346002388	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866346002389	dimer interface [polypeptide binding]; other site
866346002390	conserved gate region; other site
866346002391	ABC-ATPase subunit interface; other site
866346002392	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
866346002393	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
866346002394	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866346002395	Walker A/P-loop; other site
866346002396	ATP binding site [chemical binding]; other site
866346002397	Q-loop/lid; other site
866346002398	ABC transporter signature motif; other site
866346002399	Walker B; other site
866346002400	D-loop; other site
866346002401	H-loop/switch region; other site
866346002402	excinuclease ABC, C subunit; Region: uvrC; TIGR00194
866346002403	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
866346002404	GIY-YIG motif/motif A; other site
866346002405	active site
866346002406	catalytic site [active]
866346002407	putative DNA binding site [nucleotide binding]; other site
866346002408	metal binding site [ion binding]; metal-binding site
866346002409	UvrB/uvrC motif; Region: UVR; pfam02151
866346002410	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
866346002411	homoserine dehydrogenase; Provisional; Region: PRK06349
866346002412	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
866346002413	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
866346002414	Predicted endonuclease distantly related to archaeal Holliday junction resolvase [DNA replication, recombination, and repair]; Region: COG0792
866346002415	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
866346002416	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
866346002417	catalytic residues [active]
866346002418	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
866346002419	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
866346002420	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866346002421	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
866346002422	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
866346002423	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
866346002424	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
866346002425	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
866346002426	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
866346002427	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
866346002428	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
866346002429	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
866346002430	active site
866346002431	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; Region: gatA; TIGR00132
866346002432	indole acetimide hydrolase; Validated; Region: PRK07488
866346002433	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
866346002434	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
866346002435	CoA-binding site [chemical binding]; other site
866346002436	spermidine synthase; Provisional; Region: speE; PRK00536
866346002437	spermidine synthase; Provisional; Region: PRK00811
866346002438	GTP-binding protein Der; Reviewed; Region: PRK00093
866346002439	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
866346002440	G1 box; other site
866346002441	GTP/Mg2+ binding site [chemical binding]; other site
866346002442	Switch I region; other site
866346002443	G2 box; other site
866346002444	Switch II region; other site
866346002445	G3 box; other site
866346002446	G4 box; other site
866346002447	G5 box; other site
866346002448	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
866346002449	G1 box; other site
866346002450	GTP/Mg2+ binding site [chemical binding]; other site
866346002451	Switch I region; other site
866346002452	G2 box; other site
866346002453	G3 box; other site
866346002454	Switch II region; other site
866346002455	G4 box; other site
866346002456	G5 box; other site
866346002457	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
866346002458	IHF dimer interface [polypeptide binding]; other site
866346002459	IHF - DNA interface [nucleotide binding]; other site
866346002460	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
866346002461	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
866346002462	Long-chain fatty acid transport protein [Lipid metabolism]; Region: FadL; COG2067
866346002463	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
866346002464	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
866346002465	NAD(P) binding site [chemical binding]; other site
866346002466	homodimer interface [polypeptide binding]; other site
866346002467	substrate binding site [chemical binding]; other site
866346002468	active site
866346002469	phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Region: coaBC_dfp; TIGR00521
866346002470	Flavoprotein; Region: Flavoprotein; pfam02441
866346002471	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
866346002472	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
866346002473	thiamine phosphate binding site [chemical binding]; other site
866346002474	active site
866346002475	pyrophosphate binding site [ion binding]; other site
866346002476	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
866346002477	dimer interface [polypeptide binding]; other site
866346002478	substrate binding site [chemical binding]; other site
866346002479	ATP binding site [chemical binding]; other site
866346002480	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
866346002481	substrate binding site [chemical binding]; other site
866346002482	multimerization interface [polypeptide binding]; other site
866346002483	ATP binding site [chemical binding]; other site
866346002484	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
866346002485	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
866346002486	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866346002487	ATP binding site [chemical binding]; other site
866346002488	putative Mg++ binding site [ion binding]; other site
866346002489	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866346002490	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
866346002491	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866346002492	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
866346002493	HsdM N-terminal domain; Region: HsdM_N; pfam12161
866346002494	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866346002495	S-adenosylmethionine binding site [chemical binding]; other site
866346002496	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
866346002497	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
866346002498	active site
866346002499	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2958
866346002500	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
866346002501	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866346002502	Walker A/P-loop; other site
866346002503	ATP binding site [chemical binding]; other site
866346002504	Q-loop/lid; other site
866346002505	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
866346002506	ABC transporter; Region: ABC_tran_2; pfam12848
866346002507	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
866346002508	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
866346002509	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
866346002510	active site
866346002511	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
866346002512	dimer interface [polypeptide binding]; other site
866346002513	active site
866346002514	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
866346002515	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
866346002516	putative ribose interaction site [chemical binding]; other site
866346002517	putative ADP binding site [chemical binding]; other site
866346002518	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
866346002519	active site
866346002520	nucleotide binding site [chemical binding]; other site
866346002521	HIGH motif; other site
866346002522	KMSKS motif; other site
866346002523	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
866346002524	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
866346002525	NAD(P) binding site [chemical binding]; other site
866346002526	active site
866346002527	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
866346002528	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866346002529	active site
866346002530	motif I; other site
866346002531	motif II; other site
866346002532	Uncharacterized conserved protein [Function unknown]; Region: COG2836
866346002533	pantothenate kinase; Reviewed; Region: PRK13333
866346002534	PQQ-like domain; Region: PQQ_2; pfam13360
866346002535	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
866346002536	trimer interface [polypeptide binding]; other site
866346002537	active site
866346002538	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
866346002539	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
866346002540	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
866346002541	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
866346002542	lipid-A-disaccharide synthase; Region: lpxB; TIGR00215
866346002543	hydrogenase nickel incorporation protein; Provisional; Region: hypA; PRK00564
866346002544	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
866346002545	flagellar hook protein FlgE; Validated; Region: flgE; PRK08425
866346002546	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
866346002547	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
866346002548	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
866346002549	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
866346002550	CDP-diacylglycerol pyrophosphatase; Region: CDH; cl00934
866346002551	alkylphosphonate utilization operon protein PhnA; Region: phnA; TIGR00686
866346002552	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
866346002553	PhnA protein; Region: PhnA; pfam03831
866346002554	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
866346002555	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
866346002556	tetramer interface [polypeptide binding]; other site
866346002557	heme binding pocket [chemical binding]; other site
866346002558	NADPH binding site [chemical binding]; other site
866346002559	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
866346002560	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866346002561	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866346002562	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
866346002563	active site
866346002564	putative DNA-binding cleft [nucleotide binding]; other site
866346002565	dimer interface [polypeptide binding]; other site
866346002566	Uncharacterized conserved protein [Function unknown]; Region: COG1432
866346002567	LabA_like proteins; Region: LabA_like; cd06167
866346002568	putative metal binding site [ion binding]; other site
866346002569	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
866346002570	Holliday junction DNA helicase, RuvA subunit; Region: ruvA; TIGR00084
866346002571	RuvA N terminal domain; Region: RuvA_N; pfam01330
866346002572	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
866346002573	Protein of unknown function (DUF342); Region: DUF342; pfam03961
866346002574	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
866346002575	MviN-like protein; Region: MVIN; pfam03023
866346002576	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
866346002577	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
866346002578	active site
866346002579	HIGH motif; other site
866346002580	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
866346002581	KMSKS motif; other site
866346002582	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
866346002583	tRNA binding surface [nucleotide binding]; other site
866346002584	anticodon binding site; other site
866346002585	Vacuolating cyotoxin; Region: VacA; pfam02691
866346002586	Autotransporter beta-domain; Region: Autotransporter; pfam03797
866346002587	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
866346002588	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
866346002589	Walker A/P-loop; other site
866346002590	ATP binding site [chemical binding]; other site
866346002591	Q-loop/lid; other site
866346002592	ABC transporter signature motif; other site
866346002593	Walker B; other site
866346002594	D-loop; other site
866346002595	H-loop/switch region; other site
866346002596	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
866346002597	ABC-ATPase subunit  interface; other site
866346002598	dimer interface [polypeptide binding]; other site
866346002599	putative PBP binding regions; other site
866346002600	short chain dehydrogenase; Validated; Region: PRK06182
866346002601	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
866346002602	NADP binding site [chemical binding]; other site
866346002603	active site
866346002604	steroid binding site; other site
866346002605	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
866346002606	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346002607	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
866346002608	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
866346002609	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypC; COG0298
866346002610	hydrogenase accessory protein HypB; Region: hypB; TIGR00073
866346002611	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
866346002612	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
866346002613	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
866346002614	propionate/acetate kinase; Provisional; Region: PRK12379
866346002615	BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; Region: Pta; COG0857
866346002616	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
866346002617	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
866346002618	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK05842
866346002619	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
866346002620	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
866346002621	flagellar hook protein FlgE; Validated; Region: flgE; PRK05841
866346002622	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
866346002623	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
866346002624	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866346002625	S-adenosylmethionine binding site [chemical binding]; other site
866346002626	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
866346002627	Part of AAA domain; Region: AAA_19; pfam13245
866346002628	Family description; Region: UvrD_C_2; pfam13538
866346002629	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346002630	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346002631	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866346002632	potential frameshift: common BLAST hit: gi|308183069|ref|YP_003927196.1| iron-regulated outer membrane protein
866346002633	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
866346002634	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866346002635	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866346002636	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
866346002637	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
866346002638	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
866346002639	ATP-grasp domain; Region: ATP-grasp_4; cl17255
866346002640	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
866346002641	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
866346002642	ATP-grasp domain; Region: ATP-grasp_4; cl17255
866346002643	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
866346002644	IMP binding site; other site
866346002645	dimer interface [polypeptide binding]; other site
866346002646	interdomain contacts; other site
866346002647	partial ornithine binding site; other site
866346002648	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
866346002649	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
866346002650	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
866346002651	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
866346002652	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
866346002653	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866346002654	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866346002655	PPE-repeat proteins [Cell motility and secretion]; Region: COG5651
866346002656	Putative vacuolating cytotoxin; Region: VacA2; pfam03077
866346002657	Autotransporter beta-domain; Region: Autotransporter; pfam03797
866346002658	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346002659	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
866346002660	active site 1 [active]
866346002661	dimer interface [polypeptide binding]; other site
866346002662	hexamer interface [polypeptide binding]; other site
866346002663	active site 2 [active]
866346002664	recombination protein RecR; Region: recR; TIGR00615
866346002665	RecR protein; Region: RecR; pfam02132
866346002666	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
866346002667	putative active site [active]
866346002668	putative metal-binding site [ion binding]; other site
866346002669	tetramer interface [polypeptide binding]; other site
866346002670	tRNA pseudouridine synthase, TruD family; Region: tRNA_TruD_broad; TIGR00094
866346002671	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
866346002672	Permutation of conserved domain; other site
866346002673	active site
866346002674	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
866346002675	heat shock protein HtpX; Provisional; Region: PRK02870
866346002676	GTP cyclohydrolase I; Region: folE; TIGR00063
866346002677	GTP cyclohydrolase I; Provisional; Region: PLN03044
866346002678	active site
866346002679	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
866346002680	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
866346002681	substrate binding pocket [chemical binding]; other site
866346002682	chain length determination region; other site
866346002683	substrate-Mg2+ binding site; other site
866346002684	catalytic residues [active]
866346002685	aspartate-rich region 1; other site
866346002686	active site lid residues [active]
866346002687	aspartate-rich region 2; other site
866346002688	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
866346002689	6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Region: COG0720
866346002690	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
866346002691	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
866346002692	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
866346002693	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866346002694	Coenzyme A binding pocket [chemical binding]; other site
866346002695	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346002696	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866346002697	putative substrate translocation pore; other site
866346002698	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866346002699	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866346002700	Protein of unknown function DUF262; Region: DUF262; pfam03235
866346002701	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
866346002702	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866346002703	dimer interface [polypeptide binding]; other site
866346002704	conserved gate region; other site
866346002705	putative PBP binding loops; other site
866346002706	ABC-ATPase subunit interface; other site
866346002707	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
866346002708	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866346002709	substrate binding pocket [chemical binding]; other site
866346002710	membrane-bound complex binding site; other site
866346002711	hinge residues; other site
866346002712	alanine racemase; Region: alr; TIGR00492
866346002713	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
866346002714	active site
866346002715	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866346002716	dimer interface [polypeptide binding]; other site
866346002717	substrate binding site [chemical binding]; other site
866346002718	catalytic residues [active]
866346002719	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
866346002720	amino acid carrier protein; Region: agcS; TIGR00835
866346002721	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
866346002722	Streptococcal 67 kDa myosin-cross-reactive antigen like family; Region: Strep_67kDa_ant; cl17487
866346002723	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
866346002724	homotrimer interaction site [polypeptide binding]; other site
866346002725	putative active site [active]
866346002726	TRL-like protein family; Region: TRL; pfam13146
866346002727	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
866346002728	Uncharacterized conserved protein [Function unknown]; Region: COG1576
866346002729	acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Region: accD; TIGR00515
866346002730	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
866346002731	putative recombination protein RecO; Provisional; Region: PRK13908
866346002732	competence/damage-inducible protein CinA C-terminal domain; Region: cinA_cterm; TIGR00199
866346002733	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
866346002734	dimer interface [polypeptide binding]; other site
866346002735	FMN binding site [chemical binding]; other site
866346002736	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
866346002737	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
866346002738	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
866346002739	active site
866346002740	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
866346002741	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
866346002742	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
866346002743	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
866346002744	Putative zinc ribbon domain; Region: DUF164; pfam02591
866346002745	Uncharacterized conserved protein [Function unknown]; Region: COG0327
866346002746	dinuclear metal center protein, YbgI/SA1388 family; Region: YbgI_SA1388; TIGR00486
866346002747	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
866346002748	dimer interface [polypeptide binding]; other site
866346002749	motif 1; other site
866346002750	active site
866346002751	motif 2; other site
866346002752	motif 3; other site
866346002753	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
866346002754	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
866346002755	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
866346002756	potential frameshift: common BLAST hit: gi|254779561|ref|YP_003057667.1| ATPase
866346002757	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
866346002758	Dynamin family; Region: Dynamin_N; pfam00350
866346002759	G1 box; other site
866346002760	GTP/Mg2+ binding site [chemical binding]; other site
866346002761	G2 box; other site
866346002762	Switch I region; other site
866346002763	G3 box; other site
866346002764	Switch II region; other site
866346002765	G4 box; other site
866346002766	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
866346002767	G3 box; other site
866346002768	Switch II region; other site
866346002769	G4 box; other site
866346002770	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
866346002771	G1 box; other site
866346002772	GTP/Mg2+ binding site [chemical binding]; other site
866346002773	G2 box; other site
866346002774	Switch I region; other site
866346002775	Protein of unknown function (DUF3240); Region: DUF3240; pfam11582
866346002776	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
866346002777	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
866346002778	HlyD family secretion protein; Region: HlyD_3; pfam13437
866346002779	Outer membrane efflux protein; Region: OEP; pfam02321
866346002780	Outer membrane efflux protein; Region: OEP; pfam02321
866346002781	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
866346002782	phosphoglyceromutase; Provisional; Region: PRK05434
866346002783	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
866346002784	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; Region: gatC; TIGR00135
866346002785	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
866346002786	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
866346002787	inhibitor-cofactor binding pocket; inhibition site
866346002788	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866346002789	catalytic residue [active]
866346002790	SurA N-terminal domain; Region: SurA_N_3; cl07813
866346002791	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
866346002792	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
866346002793	cell division protein FtsA; Region: ftsA; TIGR01174
866346002794	Cell division protein FtsA; Region: FtsA; smart00842
866346002795	Cell division protein FtsA; Region: FtsA; pfam14450
866346002796	cell division protein FtsZ; Validated; Region: PRK09330
866346002797	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
866346002798	nucleotide binding site [chemical binding]; other site
866346002799	SulA interaction site; other site
866346002800	Mechanosensitive ion channel; Region: MS_channel; pfam00924
866346002801	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866346002802	Protein of unknown function DUF262; Region: DUF262; pfam03235
866346002803	Protein of unknown function DUF262; Region: DUF262; pfam03235
866346002804	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866346002805	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
866346002806	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
866346002807	active site
866346002808	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866346002809	catalytic residues [active]
866346002810	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
866346002811	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
866346002812	This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1; Region: GT1_UGDG_like; cd03817
866346002813	putative ADP-binding pocket [chemical binding]; other site
866346002814	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
866346002815	active site 2 [active]
866346002816	active site 1 [active]
866346002817	Methyltransferase domain; Region: Methyltransf_23; pfam13489
866346002818	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866346002819	S-adenosylmethionine binding site [chemical binding]; other site
866346002820	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
866346002821	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
866346002822	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
866346002823	active site
866346002824	HIGH motif; other site
866346002825	KMSKS motif; other site
866346002826	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
866346002827	anticodon binding site; other site
866346002828	tRNA binding surface [nucleotide binding]; other site
866346002829	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
866346002830	dimer interface [polypeptide binding]; other site
866346002831	putative tRNA-binding site [nucleotide binding]; other site
866346002832	Mycolic acid cyclopropane synthetase; Region: CMAS; pfam02353
866346002833	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866346002834	S-adenosylmethionine binding site [chemical binding]; other site
866346002835	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
866346002836	Mechanosensitive ion channel; Region: MS_channel; pfam00924
866346002837	Neuraminyllactose-binding hemagglutinin precursor (NLBH); Region: NLBH; pfam05211
866346002838	GMP synthase; Reviewed; Region: guaA; PRK00074
866346002839	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
866346002840	AMP/PPi binding site [chemical binding]; other site
866346002841	candidate oxyanion hole; other site
866346002842	catalytic triad [active]
866346002843	potential glutamine specificity residues [chemical binding]; other site
866346002844	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
866346002845	ATP Binding subdomain [chemical binding]; other site
866346002846	Ligand Binding sites [chemical binding]; other site
866346002847	Dimerization subdomain; other site
866346002848	potential frameshift: common BLAST hit: gi|188527828|ref|YP_001910515.1| biotin sulfoxide reductase BisC
866346002849	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
866346002850	molybdopterin cofactor binding site; other site
866346002851	potential frameshift: common BLAST hit: gi|210135206|ref|YP_002301645.1| biotin sulfoxide reductase
866346002852	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866346002853	potential frameshift: common BLAST hit: gi|108563410|ref|YP_627726.1| biotin sulfoxide reductase
866346002854	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866346002855	potential frameshift: common BLAST hit: gi|308183150|ref|YP_003927277.1| biotin sulfoxide reductase (bisC)
866346002856	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866346002857	molybdopterin cofactor binding site; other site
866346002858	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866346002859	Protein of unknown function (DUF3972); Region: DUF3972; pfam13118
866346002860	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
866346002861	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
866346002862	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866346002863	catalytic residue [active]
866346002864	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
866346002865	nucleotide binding site/active site [active]
866346002866	HIT family signature motif; other site
866346002867	catalytic residue [active]
866346002868	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
866346002869	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
866346002870	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
866346002871	dimer interface [polypeptide binding]; other site
866346002872	motif 1; other site
866346002873	active site
866346002874	motif 2; other site
866346002875	motif 3; other site
866346002876	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
866346002877	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
866346002878	putative tRNA-binding site [nucleotide binding]; other site
866346002879	tRNA synthetase B5 domain; Region: B5; pfam03484
866346002880	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
866346002881	dimer interface [polypeptide binding]; other site
866346002882	motif 1; other site
866346002883	motif 3; other site
866346002884	motif 2; other site
866346002885	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
866346002886	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
866346002887	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
866346002888	hinge; other site
866346002889	active site
866346002890	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
866346002891	LytB protein; Region: LYTB; pfam02401
866346002892	ribosomal protein S1; Region: rpsA; TIGR00717
866346002893	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
866346002894	RNA binding site [nucleotide binding]; other site
866346002895	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
866346002896	RNA binding site [nucleotide binding]; other site
866346002897	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
866346002898	RNA binding site [nucleotide binding]; other site
866346002899	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
866346002900	RNA binding site [nucleotide binding]; other site
866346002901	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
866346002902	RNA binding site [nucleotide binding]; other site
866346002903	D-3-phosphoglycerate dehydrogenase; Region: PGDH; TIGR01327
866346002904	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
866346002905	ligand binding site [chemical binding]; other site
866346002906	NAD binding site [chemical binding]; other site
866346002907	dimerization interface [polypeptide binding]; other site
866346002908	catalytic site [active]
866346002909	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
866346002910	putative L-serine binding site [chemical binding]; other site
866346002911	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
866346002912	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
866346002913	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
866346002914	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866346002915	catalytic residue [active]
866346002916	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
866346002917	putative active site [active]
866346002918	putative metal binding site [ion binding]; other site
866346002919	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
866346002920	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
866346002921	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866346002922	active site
866346002923	phosphorylation site [posttranslational modification]
866346002924	intermolecular recognition site; other site
866346002925	dimerization interface [polypeptide binding]; other site
866346002926	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
866346002927	putative binding surface; other site
866346002928	active site
866346002929	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
866346002930	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
866346002931	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866346002932	ATP binding site [chemical binding]; other site
866346002933	Mg2+ binding site [ion binding]; other site
866346002934	G-X-G motif; other site
866346002935	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
866346002936	Response regulator receiver domain; Region: Response_reg; pfam00072
866346002937	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866346002938	active site
866346002939	phosphorylation site [posttranslational modification]
866346002940	intermolecular recognition site; other site
866346002941	dimerization interface [polypeptide binding]; other site
866346002942	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
866346002943	putative CheA interaction surface; other site
866346002944	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
866346002945	dimer interface [polypeptide binding]; other site
866346002946	catalytic triad [active]
866346002947	peroxidatic and resolving cysteines [active]
866346002948	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
866346002949	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
866346002950	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
866346002951	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
866346002952	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866346002953	S-adenosylmethionine binding site [chemical binding]; other site
866346002954	primosome assembly protein PriA; Validated; Region: PRK05580
866346002955	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866346002956	ATP binding site [chemical binding]; other site
866346002957	putative Mg++ binding site [ion binding]; other site
866346002958	helicase superfamily c-terminal domain; Region: HELICc; smart00490
866346002959	Sporulation related domain; Region: SPOR; pfam05036
866346002960	Peptidase family M48; Region: Peptidase_M48; pfam01435
866346002961	HemK family putative methylases; Region: hemK_fam; TIGR00536
866346002962	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
866346002963	glutamate dehydrogenase; Provisional; Region: PRK09414
866346002964	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
866346002965	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
866346002966	NAD(P) binding site [chemical binding]; other site
866346002967	Glycosyltransferase family 10 (fucosyltransferase); Region: Glyco_transf_10; pfam00852
866346002968	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
866346002969	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
866346002970	SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide...; Region: SoxW; cd02951
866346002971	catalytic residues [active]
866346002972	ferrochelatase; Region: hemH; TIGR00109
866346002973	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
866346002974	C-terminal domain interface [polypeptide binding]; other site
866346002975	active site
866346002976	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
866346002977	active site
866346002978	N-terminal domain interface [polypeptide binding]; other site
866346002979	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
866346002980	RNA methyltransferase, RsmE family; Region: TIGR00046
866346002981	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346002982	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
866346002983	trimer interface [polypeptide binding]; other site
866346002984	active site
866346002985	acetyl-CoA carboxylase, biotin carboxyl carrier protein; Region: BCCP; TIGR00531
866346002986	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
866346002987	carboxyltransferase (CT) interaction site; other site
866346002988	biotinylation site [posttranslational modification]; other site
866346002989	biotin carboxylase; Validated; Region: PRK08462
866346002990	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
866346002991	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
866346002992	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
866346002993	Methyltransferase domain; Region: Methyltransf_26; pfam13659
866346002994	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
866346002995	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
866346002996	inhibitor-cofactor binding pocket; inhibition site
866346002997	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866346002998	catalytic residue [active]
866346002999	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
866346003000	dimer interface [polypeptide binding]; other site
866346003001	putative radical transfer pathway; other site
866346003002	diiron center [ion binding]; other site
866346003003	tyrosyl radical; other site
866346003004	protein-L-isoaspartate(D-aspartate) O-methyltransferase; Region: pimt; TIGR00080
866346003005	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866346003006	S-adenosylmethionine binding site [chemical binding]; other site
866346003007	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
866346003008	Predicted permeases [General function prediction only]; Region: COG0795
866346003009	tRNA pseudouridine(38-40) synthase; Region: hisT_truA; TIGR00071
866346003010	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
866346003011	dimerization interface 3.5A [polypeptide binding]; other site
866346003012	active site
866346003013	UDP-glucose-4-epimerase GalE; Region: galE; TIGR01179
866346003014	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
866346003015	NAD binding site [chemical binding]; other site
866346003016	homodimer interface [polypeptide binding]; other site
866346003017	active site
866346003018	substrate binding site [chemical binding]; other site
866346003019	potential frameshift: common BLAST hit: gi|15612088|ref|NP_223740.1| short chain alcohol dehydrogenase
866346003020	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
866346003021	NAD(P) binding site [chemical binding]; other site
866346003022	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
866346003023	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
866346003024	active site
866346003025	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866346003026	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866346003027	binding surface
866346003028	TPR motif; other site
866346003029	Sel1-like repeats; Region: SEL1; smart00671
866346003030	Sel1-like repeats; Region: SEL1; smart00671
866346003031	Sel1-like repeats; Region: SEL1; smart00671
866346003032	Entner-Doudoroff aldolase; Region: eda; TIGR01182
866346003033	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
866346003034	active site
866346003035	intersubunit interface [polypeptide binding]; other site
866346003036	catalytic residue [active]
866346003037	phosphogluconate dehydratase; Validated; Region: PRK09054
866346003038	6-phosphogluconate dehydratase; Region: edd; TIGR01196
866346003039	Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Region: Zwf; COG0364
866346003040	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
866346003041	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
866346003042	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
866346003043	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
866346003044	putative active site [active]
866346003045	glucokinase, proteobacterial type; Region: glk; TIGR00749
866346003046	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
866346003047	nucleotide binding site [chemical binding]; other site
866346003048	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
866346003049	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
866346003050	putative NAD(P) binding site [chemical binding]; other site
866346003051	putative substrate binding site [chemical binding]; other site
866346003052	catalytic Zn binding site [ion binding]; other site
866346003053	structural Zn binding site [ion binding]; other site
866346003054	dimer interface [polypeptide binding]; other site
866346003055	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
866346003056	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
866346003057	active site
866346003058	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
866346003059	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
866346003060	active site
866346003061	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346003062	pyruvate flavodoxin oxidoreductase subunit gamma; Validated; Region: PRK05844
866346003063	pyruvate/ketoisovalerate ferredoxin oxidoreductase subunit gamma; Provisional; Region: PRK14029
866346003064	pyruvate flavodoxin oxidoreductase subunit delta; Reviewed; Region: porD; PRK09625
866346003065	4Fe-4S binding domain; Region: Fer4; pfam00037
866346003066	pyruvate flavodoxin oxidoreductase subunit alpha; Reviewed; Region: porA; PRK09622
866346003067	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
866346003068	dimer interface [polypeptide binding]; other site
866346003069	PYR/PP interface [polypeptide binding]; other site
866346003070	TPP binding site [chemical binding]; other site
866346003071	substrate binding site [chemical binding]; other site
866346003072	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
866346003073	pyruvate ferredoxin oxidoreductase subunit beta; Provisional; Region: PRK11865
866346003074	Thiamine pyrophosphate (TPP family), PFOR porB-like subfamily, TPP-binding module; composed of proteins similar to the beta subunit (porB) of the Helicobacter pylori four-subunit pyruvate ferredoxin oxidoreductase (PFOR), which are also found in archaea...; Region: TPP_PFOR_porB_like; cd03376
866346003075	TPP-binding site [chemical binding]; other site
866346003076	putative dimer interface [polypeptide binding]; other site
866346003077	adenylosuccinate lyase; Provisional; Region: PRK08470
866346003078	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
866346003079	tetramer interface [polypeptide binding]; other site
866346003080	active site
866346003081	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
866346003082	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346003083	excinuclease ABC subunit B; Provisional; Region: PRK05298
866346003084	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866346003085	ATP binding site [chemical binding]; other site
866346003086	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
866346003087	putative Mg++ binding site [ion binding]; other site
866346003088	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866346003089	nucleotide binding region [chemical binding]; other site
866346003090	ATP-binding site [chemical binding]; other site
866346003091	Ultra-violet resistance protein B; Region: UvrB; pfam12344
866346003092	UvrB/uvrC motif; Region: UVR; pfam02151
866346003093	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866346003094	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866346003095	binding surface
866346003096	TPR motif; other site
866346003097	Sel1-like repeats; Region: SEL1; smart00671
866346003098	Sel1-like repeats; Region: SEL1; smart00671
866346003099	Sel1 repeat; Region: Sel1; cl02723
866346003100	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
866346003101	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
866346003102	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08471
866346003103	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
866346003104	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
866346003105	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
866346003106	cofactor binding site; other site
866346003107	DNA binding site [nucleotide binding]
866346003108	substrate interaction site [chemical binding]; other site
866346003109	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
866346003110	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
866346003111	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
866346003112	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
866346003113	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
866346003114	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
866346003115	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
866346003116	ligand binding site [chemical binding]; other site
866346003117	translocation protein TolB; Provisional; Region: tolB; PRK04043
866346003118	TolB amino-terminal domain; Region: TolB_N; pfam04052
866346003119	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
866346003120	TonB C terminal; Region: TonB_2; pfam13103
866346003121	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
866346003122	TolR protein; Region: tolR; TIGR02801
866346003123	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
866346003124	ATP synthase, F1 epsilon subunit (delta in mitochondria); Region: ATP_synt_epsi; TIGR01216
866346003125	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
866346003126	gamma subunit interface [polypeptide binding]; other site
866346003127	epsilon subunit interface [polypeptide binding]; other site
866346003128	LBP interface [polypeptide binding]; other site
866346003129	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
866346003130	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
866346003131	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
866346003132	alpha subunit interaction interface [polypeptide binding]; other site
866346003133	Walker A motif; other site
866346003134	ATP binding site [chemical binding]; other site
866346003135	Walker B motif; other site
866346003136	inhibitor binding site; inhibition site
866346003137	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
866346003138	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
866346003139	core domain interface [polypeptide binding]; other site
866346003140	delta subunit interface [polypeptide binding]; other site
866346003141	epsilon subunit interface [polypeptide binding]; other site
866346003142	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
866346003143	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
866346003144	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
866346003145	beta subunit interaction interface [polypeptide binding]; other site
866346003146	Walker A motif; other site
866346003147	ATP binding site [chemical binding]; other site
866346003148	Walker B motif; other site
866346003149	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
866346003150	F0F1 ATP synthase subunit delta; Provisional; Region: PRK13431
866346003151	F0F1 ATP synthase subunit B; Validated; Region: PRK08475
866346003152	F0F1 ATP synthase subunit B'; Validated; Region: PRK08476
866346003153	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
866346003154	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
866346003155	ParB-like nuclease domain; Region: ParB; smart00470
866346003156	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
866346003157	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
866346003158	P-loop; other site
866346003159	Magnesium ion binding site [ion binding]; other site
866346003160	biotin--protein ligase; Provisional; Region: PRK08477
866346003161	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
866346003162	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
866346003163	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
866346003164	putative active site [active]
866346003165	substrate binding site [chemical binding]; other site
866346003166	putative cosubstrate binding site; other site
866346003167	catalytic site [active]
866346003168	Formyl transferase, C-terminal domain; Region: Formyl_trans_C; pfam02911
866346003169	AAA domain; Region: AAA_13; pfam13166
866346003170	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
866346003171	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
866346003172	Uncharacterized conserved protein [Function unknown]; Region: COG1432
866346003173	LabA_like proteins; Region: LabA_like; cd06167
866346003174	putative metal binding site [ion binding]; other site
866346003175	LabA_like proteins; Region: LabA_like; cd06167
866346003176	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
866346003177	tRNA (Guanine-1)-methyltransferase; Region: tRNA_m1G_MT; cl00407
866346003178	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK14593
866346003179	RimM N-terminal domain; Region: RimM; pfam01782
866346003180	PRC-barrel domain; Region: PRC; pfam05239
866346003181	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
866346003182	KH domain; Region: KH_4; pfam13083
866346003183	G-X-X-G motif; other site
866346003184	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
866346003185	signal recognition particle protein; Provisional; Region: PRK10867
866346003186	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
866346003187	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
866346003188	P loop; other site
866346003189	GTP binding site [chemical binding]; other site
866346003190	Signal peptide binding domain; Region: SRP_SPB; pfam02978
866346003191	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
866346003192	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
866346003193	active site
866346003194	HIGH motif; other site
866346003195	nucleotide binding site [chemical binding]; other site
866346003196	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
866346003197	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
866346003198	active site
866346003199	KMSKS motif; other site
866346003200	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
866346003201	anticodon binding site; other site
866346003202	flagellar assembly protein FliW; Provisional; Region: PRK13283
866346003203	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
866346003204	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
866346003205	active site
866346003206	homodimer interface [polypeptide binding]; other site
866346003207	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346003208	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346003209	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
866346003210	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
866346003211	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
866346003212	Fic/DOC family; Region: Fic; cl00960
866346003213	metal-binding heat shock protein; Provisional; Region: PRK00016
866346003214	flavodoxin FldA; Validated; Region: PRK09267
866346003215	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
866346003216	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
866346003217	Uncharacterized protein, possibly involved in nitrogen fixation [Inorganic ion transport and metabolism]; Region: FixS; COG3197
866346003218	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
866346003219	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
866346003220	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866346003221	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
866346003222	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
866346003223	active site
866346003224	dimer interface [polypeptide binding]; other site
866346003225	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
866346003226	dimer interface [polypeptide binding]; other site
866346003227	active site
866346003228	Putative outer membrane protein; Region: HP_OMP_2; pfam02521
866346003229	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
866346003230	Methyltransferase domain; Region: Methyltransf_26; pfam13659
866346003231	carbon starvation protein A; Provisional; Region: PRK15015
866346003232	Carbon starvation protein CstA; Region: CstA; pfam02554
866346003233	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
866346003234	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
866346003235	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866346003236	dimer interface [polypeptide binding]; other site
866346003237	conserved gate region; other site
866346003238	putative PBP binding loops; other site
866346003239	ABC-ATPase subunit interface; other site
866346003240	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866346003241	dimer interface [polypeptide binding]; other site
866346003242	conserved gate region; other site
866346003243	putative PBP binding loops; other site
866346003244	ABC-ATPase subunit interface; other site
866346003245	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
866346003246	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
866346003247	Walker A/P-loop; other site
866346003248	ATP binding site [chemical binding]; other site
866346003249	Q-loop/lid; other site
866346003250	ABC transporter signature motif; other site
866346003251	Walker B; other site
866346003252	D-loop; other site
866346003253	H-loop/switch region; other site
866346003254	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
866346003255	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866346003256	substrate binding pocket [chemical binding]; other site
866346003257	membrane-bound complex binding site; other site
866346003258	hinge residues; other site
866346003259	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
866346003260	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866346003261	putative substrate translocation pore; other site
866346003262	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
866346003263	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346003264	purine-nucleoside phosphorylase, family 1 (deoD); Region: deoD; TIGR00107
866346003265	phosphopentomutase; Provisional; Region: PRK05362
866346003266	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
866346003267	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
866346003268	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
866346003269	Nucleoside recognition; Region: Gate; pfam07670
866346003270	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
866346003271	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866346003272	Major Facilitator Superfamily; Region: MFS_1; pfam07690
866346003273	putative substrate translocation pore; other site
866346003274	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
866346003275	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
866346003276	Ligand Binding Site [chemical binding]; other site
866346003277	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
866346003278	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
866346003279	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
866346003280	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
866346003281	putative arabinose transporter; Provisional; Region: PRK03545
866346003282	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866346003283	putative substrate translocation pore; other site
866346003284	Carbonic anhydrase [Inorganic ion transport and metabolism]; Region: Cah; COG3338
866346003285	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
866346003286	active site
866346003287	zinc binding site [ion binding]; other site
866346003288	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
866346003289	Helicobacter pylori protein of unknown function (DUF874); Region: DUF874; pfam05917
866346003290	aspartate-semialdehyde dehydrogenase (peptidoglycan organisms); Region: asd_B; TIGR01296
866346003291	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
866346003292	Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: HisS; COG0124
866346003293	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
866346003294	dimer interface [polypeptide binding]; other site
866346003295	motif 1; other site
866346003296	active site
866346003297	motif 2; other site
866346003298	motif 3; other site
866346003299	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
866346003300	anticodon binding site; other site
866346003301	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
866346003302	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
866346003303	putative active site [active]
866346003304	elongation factor G; Reviewed; Region: PRK00007
866346003305	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
866346003306	G1 box; other site
866346003307	putative GEF interaction site [polypeptide binding]; other site
866346003308	GTP/Mg2+ binding site [chemical binding]; other site
866346003309	Switch I region; other site
866346003310	G2 box; other site
866346003311	G3 box; other site
866346003312	Switch II region; other site
866346003313	G4 box; other site
866346003314	G5 box; other site
866346003315	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
866346003316	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
866346003317	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
866346003318	30S ribosomal protein S7; Validated; Region: PRK05302
866346003319	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
866346003320	S17 interaction site [polypeptide binding]; other site
866346003321	S8 interaction site; other site
866346003322	16S rRNA interaction site [nucleotide binding]; other site
866346003323	streptomycin interaction site [chemical binding]; other site
866346003324	23S rRNA interaction site [nucleotide binding]; other site
866346003325	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
866346003326	bifunctional DNA-directed RNA polymerase subunit beta/beta'; Reviewed; Region: PRK09603
866346003327	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
866346003328	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
866346003329	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
866346003330	RPB11 interaction site [polypeptide binding]; other site
866346003331	RPB12 interaction site [polypeptide binding]; other site
866346003332	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
866346003333	RPB3 interaction site [polypeptide binding]; other site
866346003334	RPB1 interaction site [polypeptide binding]; other site
866346003335	RPB11 interaction site [polypeptide binding]; other site
866346003336	RPB10 interaction site [polypeptide binding]; other site
866346003337	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
866346003338	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
866346003339	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
866346003340	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
866346003341	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
866346003342	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
866346003343	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
866346003344	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
866346003345	DNA binding site [nucleotide binding]
866346003346	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
866346003347	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
866346003348	core dimer interface [polypeptide binding]; other site
866346003349	peripheral dimer interface [polypeptide binding]; other site
866346003350	L10 interface [polypeptide binding]; other site
866346003351	L11 interface [polypeptide binding]; other site
866346003352	putative EF-Tu interaction site [polypeptide binding]; other site
866346003353	putative EF-G interaction site [polypeptide binding]; other site
866346003354	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
866346003355	23S rRNA interface [nucleotide binding]; other site
866346003356	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
866346003357	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
866346003358	mRNA/rRNA interface [nucleotide binding]; other site
866346003359	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
866346003360	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
866346003361	23S rRNA interface [nucleotide binding]; other site
866346003362	L7/L12 interface [polypeptide binding]; other site
866346003363	putative thiostrepton binding site; other site
866346003364	L25 interface [polypeptide binding]; other site
866346003365	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
866346003366	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
866346003367	putative homodimer interface [polypeptide binding]; other site
866346003368	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
866346003369	heterodimer interface [polypeptide binding]; other site
866346003370	homodimer interface [polypeptide binding]; other site
866346003371	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; cl00481
866346003372	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
866346003373	elongation factor Tu; Reviewed; Region: PRK00049
866346003374	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
866346003375	G1 box; other site
866346003376	GEF interaction site [polypeptide binding]; other site
866346003377	GTP/Mg2+ binding site [chemical binding]; other site
866346003378	Switch I region; other site
866346003379	G2 box; other site
866346003380	G3 box; other site
866346003381	Switch II region; other site
866346003382	G4 box; other site
866346003383	G5 box; other site
866346003384	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
866346003385	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
866346003386	Antibiotic Binding Site [chemical binding]; other site
866346003387	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
866346003388	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
866346003389	Walker A/P-loop; other site
866346003390	ATP binding site [chemical binding]; other site
866346003391	Q-loop/lid; other site
866346003392	ABC transporter signature motif; other site
866346003393	Walker B; other site
866346003394	D-loop; other site
866346003395	H-loop/switch region; other site
866346003396	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
866346003397	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
866346003398	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
866346003399	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; pfam02086
866346003400	ICEA Protein; Region: ICEA; pfam05315
866346003401	serine O-acetyltransferase; Region: cysE; TIGR01172
866346003402	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
866346003403	trimer interface [polypeptide binding]; other site
866346003404	active site
866346003405	substrate binding site [chemical binding]; other site
866346003406	CoA binding site [chemical binding]; other site
866346003407	F0F1 ATP synthase subunit C; Validated; Region: PRK08482
866346003408	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
866346003409	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
866346003410	oligomer interface [polypeptide binding]; other site
866346003411	RNA binding site [nucleotide binding]; other site
866346003412	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
866346003413	oligomer interface [polypeptide binding]; other site
866346003414	RNA binding site [nucleotide binding]; other site
866346003415	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
866346003416	putative nucleic acid binding region [nucleotide binding]; other site
866346003417	G-X-X-G motif; other site
866346003418	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
866346003419	RNA binding site [nucleotide binding]; other site
866346003420	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG1926
866346003421	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
866346003422	Organic solvent tolerance protein; Region: OstA_C; pfam04453
866346003423	Predicted membrane protein/domain [Function unknown]; Region: COG1714
866346003424	phosphoribosylamine--glycine ligase; Region: purD; TIGR00877
866346003425	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
866346003426	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
866346003427	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
866346003428	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
866346003429	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
866346003430	Walker A/P-loop; other site
866346003431	ATP binding site [chemical binding]; other site
866346003432	Q-loop/lid; other site
866346003433	ABC transporter signature motif; other site
866346003434	Walker B; other site
866346003435	D-loop; other site
866346003436	H-loop/switch region; other site
866346003437	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
866346003438	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
866346003439	catalytic residue [active]
866346003440	putative FPP diphosphate  binding site; other site
866346003441	putative FPP binding hydrophobic cleft; other site
866346003442	dimer interface [polypeptide binding]; other site
866346003443	putative IPP diphosphate binding site; other site
866346003444	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
866346003445	FAD binding domain; Region: FAD_binding_4; pfam01565
866346003446	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
866346003447	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
866346003448	active site residue [active]
866346003449	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
866346003450	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
866346003451	active site
866346003452	camphor resistance protein CrcB; Provisional; Region: PRK14204
866346003453	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
866346003454	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866346003455	FeS/SAM binding site; other site
866346003456	HemN C-terminal domain; Region: HemN_C; pfam06969
866346003457	Cytochrome c553 [Energy production and conversion]; Region: COG2863
866346003458	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
866346003459	putative active site [active]
866346003460	Ap4A binding site [chemical binding]; other site
866346003461	nudix motif; other site
866346003462	putative metal binding site [ion binding]; other site
866346003463	aspartate kinase; Reviewed; Region: PRK06635
866346003464	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
866346003465	putative nucleotide binding site [chemical binding]; other site
866346003466	putative catalytic residues [active]
866346003467	putative Mg ion binding site [ion binding]; other site
866346003468	putative aspartate binding site [chemical binding]; other site
866346003469	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
866346003470	putative allosteric regulatory site; other site
866346003471	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
866346003472	putative allosteric regulatory residue; other site
866346003473	DNA replication regulator; Region: HobA; pfam12163
866346003474	DNA polymerase III subunit delta'; Validated; Region: PRK08485
866346003475	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
866346003476	dihydropteroate synthase; Region: DHPS; TIGR01496
866346003477	substrate binding pocket [chemical binding]; other site
866346003478	dimer interface [polypeptide binding]; other site
866346003479	inhibitor binding site; inhibition site
866346003480	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
866346003481	EamA-like transporter family; Region: EamA; pfam00892
866346003482	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
866346003483	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2952
866346003484	Carbamoylphosphate synthase small subunit [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarA; COG0505
866346003485	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
866346003486	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
866346003487	catalytic site [active]
866346003488	subunit interface [polypeptide binding]; other site
866346003489	formamidase; Provisional; Region: amiF; PRK13287
866346003490	aliphatic amidases (class 2 nitrilases); Region: aliphatic_amidase; cd07565
866346003491	multimer interface [polypeptide binding]; other site
866346003492	active site
866346003493	catalytic triad [active]
866346003494	dimer interface [polypeptide binding]; other site
866346003495	Maf-like protein; Region: Maf; pfam02545
866346003496	Maf-like protein; Reviewed; Region: PRK04056
866346003497	putative active site [active]
866346003498	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
866346003499	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
866346003500	motif 1; other site
866346003501	active site
866346003502	motif 2; other site
866346003503	motif 3; other site
866346003504	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
866346003505	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
866346003506	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346003507	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
866346003508	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
866346003509	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
866346003510	dimer interface [polypeptide binding]; other site
866346003511	ssDNA binding site [nucleotide binding]; other site
866346003512	tetramer (dimer of dimers) interface [polypeptide binding]; other site
866346003513	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
866346003514	DNA polymerase III subunit delta; Validated; Region: PRK08487
866346003515	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
866346003516	Exoribonuclease R [Transcription]; Region: VacB; COG0557
866346003517	RNB domain; Region: RNB; pfam00773
866346003518	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
866346003519	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
866346003520	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
866346003521	shikimate binding site; other site
866346003522	NAD(P) binding site [chemical binding]; other site
866346003523	Bacterial SH3 domain; Region: SH3_3; pfam08239
866346003524	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
866346003525	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866346003526	dimer interface [polypeptide binding]; other site
866346003527	conserved gate region; other site
866346003528	putative PBP binding loops; other site
866346003529	ABC-ATPase subunit interface; other site
866346003530	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
866346003531	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
866346003532	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
866346003533	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
866346003534	active site
866346003535	HIGH motif; other site
866346003536	dimer interface [polypeptide binding]; other site
866346003537	KMSKS motif; other site
866346003538	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
866346003539	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866346003540	S-adenosylmethionine binding site [chemical binding]; other site
866346003541	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
866346003542	ribosome recycling factor; Reviewed; Region: frr; PRK00083
866346003543	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
866346003544	hinge region; other site
866346003545	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866346003546	active site
866346003547	RDD family; Region: RDD; pfam06271
866346003548	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
866346003549	NAD-dependent protein deacetylases, SIR2 family [Transcription]; Region: SIR2; COG0846
866346003550	NAD+ binding site [chemical binding]; other site
866346003551	substrate binding site [chemical binding]; other site
866346003552	Zn binding site [ion binding]; other site
866346003553	NADH dehydrogenase subunit A; Validated; Region: PRK08489
866346003554	NADH dehydrogenase subunit B; Validated; Region: PRK06411
866346003555	NADH dehydrogenase subunit C; Provisional; Region: PRK08491
866346003556	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
866346003557	NADH dehydrogenase subunit D; Validated; Region: PRK06075
866346003558	NADH dehydrogenase I, D subunit; Region: NuoD; TIGR01962
866346003559	NADH dehydrogenase subunit G; Validated; Region: PRK08493
866346003560	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
866346003561	catalytic loop [active]
866346003562	iron binding site [ion binding]; other site
866346003563	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
866346003564	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866346003565	molybdopterin cofactor binding site; other site
866346003566	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
866346003567	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
866346003568	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
866346003569	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
866346003570	4Fe-4S binding domain; Region: Fer4; cl02805
866346003571	4Fe-4S binding domain; Region: Fer4; pfam00037
866346003572	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
866346003573	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
866346003574	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
866346003575	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
866346003576	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
866346003577	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
866346003578	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
866346003579	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
866346003580	proton-translocating NADH-quinone oxidoreductase, chain N; Region: NDH_I_N; TIGR01770
866346003581	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
866346003582	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
866346003583	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
866346003584	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
866346003585	active site
866346003586	substrate binding site [chemical binding]; other site
866346003587	metal binding site [ion binding]; metal-binding site
866346003588	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
866346003589	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
866346003590	substrate binding site [chemical binding]; other site
866346003591	active site
866346003592	catalytic residues [active]
866346003593	heterodimer interface [polypeptide binding]; other site
866346003594	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
866346003595	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
866346003596	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866346003597	catalytic residue [active]
866346003598	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
866346003599	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
866346003600	active site
866346003601	ribulose/triose binding site [chemical binding]; other site
866346003602	phosphate binding site [ion binding]; other site
866346003603	substrate (anthranilate) binding pocket [chemical binding]; other site
866346003604	product (indole) binding pocket [chemical binding]; other site
866346003605	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
866346003606	active site
866346003607	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
866346003608	anthranilate phosphoribosyltransferase; Region: trpD; TIGR01245
866346003609	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
866346003610	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
866346003611	Glutamine amidotransferase class-I; Region: GATase; pfam00117
866346003612	glutamine binding [chemical binding]; other site
866346003613	catalytic triad [active]
866346003614	anthranilate synthase component I, proteobacterial subset; Region: trpE_proteo; TIGR00565
866346003615	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
866346003616	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
866346003617	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
866346003618	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
866346003619	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866346003620	active site
866346003621	motif I; other site
866346003622	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
866346003623	motif II; other site
866346003624	Uncharacterized conserved protein [Function unknown]; Region: COG2353
866346003625	thiaminase II; Region: salvage_TenA; TIGR04306
866346003626	Nicotinamide mononucleotide transporter [Coenzyme metabolism]; Region: PnuC; COG3201
866346003627	Thiamine pyrophosphokinase [Coenzyme metabolism]; Region: THI80; COG1564
866346003628	Thiamine pyrophosphokinase; Region: TPK; cd07995
866346003629	active site
866346003630	dimerization interface [polypeptide binding]; other site
866346003631	thiamine binding site [chemical binding]; other site
866346003632	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
866346003633	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
866346003634	alphaNTD homodimer interface [polypeptide binding]; other site
866346003635	DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type; Region: rpoA; TIGR02027
866346003636	alphaNTD - beta interaction site [polypeptide binding]; other site
866346003637	alphaNTD - beta' interaction site [polypeptide binding]; other site
866346003638	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
866346003639	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
866346003640	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
866346003641	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866346003642	RNA binding surface [nucleotide binding]; other site
866346003643	30S ribosomal protein S11; Validated; Region: PRK05309
866346003644	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
866346003645	30S ribosomal protein S13; Region: bact_S13; TIGR03631
866346003646	Ribosomal protein L36; Region: Ribosomal_L36; cl00380
866346003647	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
866346003648	rRNA binding site [nucleotide binding]; other site
866346003649	predicted 30S ribosome binding site; other site
866346003650	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
866346003651	active site
866346003652	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
866346003653	SecY translocase; Region: SecY; pfam00344
866346003654	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
866346003655	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
866346003656	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
866346003657	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
866346003658	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
866346003659	23S rRNA interface [nucleotide binding]; other site
866346003660	5S rRNA interface [nucleotide binding]; other site
866346003661	L27 interface [polypeptide binding]; other site
866346003662	L5 interface [polypeptide binding]; other site
866346003663	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
866346003664	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
866346003665	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
866346003666	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
866346003667	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
866346003668	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
866346003669	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
866346003670	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
866346003671	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
866346003672	RNA binding site [nucleotide binding]; other site
866346003673	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
866346003674	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
866346003675	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
866346003676	putative translocon interaction site; other site
866346003677	23S rRNA interface [nucleotide binding]; other site
866346003678	signal recognition particle (SRP54) interaction site; other site
866346003679	L23 interface [polypeptide binding]; other site
866346003680	trigger factor interaction site; other site
866346003681	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
866346003682	23S rRNA interface [nucleotide binding]; other site
866346003683	5S rRNA interface [nucleotide binding]; other site
866346003684	putative antibiotic binding site [chemical binding]; other site
866346003685	L25 interface [polypeptide binding]; other site
866346003686	L27 interface [polypeptide binding]; other site
866346003687	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
866346003688	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
866346003689	G-X-X-G motif; other site
866346003690	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
866346003691	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
866346003692	putative translocon binding site; other site
866346003693	protein-rRNA interface [nucleotide binding]; other site
866346003694	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
866346003695	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
866346003696	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
866346003697	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
866346003698	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
866346003699	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
866346003700	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
866346003701	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
866346003702	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
866346003703	AAA domain; Region: AAA_14; pfam13173
866346003704	Helix-turn-helix domain; Region: HTH_36; pfam13730
866346003705	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
866346003706	RNA/DNA hybrid binding site [nucleotide binding]; other site
866346003707	active site
866346003708	fumarate hydratase; Reviewed; Region: fumC; PRK00485
866346003709	Class II fumarases; Region: Fumarase_classII; cd01362
866346003710	active site
866346003711	tetramer interface [polypeptide binding]; other site
866346003712	YtkA-like; Region: YtkA; pfam13115
866346003713	Outer membrane efflux protein; Region: OEP; pfam02321
866346003714	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
866346003715	HlyD family secretion protein; Region: HlyD_3; pfam13437
866346003716	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
866346003717	Predicted branched-chain amino acid permeases (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlD; COG1687
866346003718	AzlC protein; Region: AzlC; cl00570
866346003719	chaperone protein DnaJ; Provisional; Region: PRK14288
866346003720	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
866346003721	HSP70 interaction site [polypeptide binding]; other site
866346003722	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
866346003723	substrate binding site [polypeptide binding]; other site
866346003724	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
866346003725	Zn binding sites [ion binding]; other site
866346003726	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
866346003727	substrate binding site [polypeptide binding]; other site
866346003728	dimer interface [polypeptide binding]; other site
866346003729	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
866346003730	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
866346003731	Ligand Binding Site [chemical binding]; other site
866346003732	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
866346003733	HSP70 interaction site [polypeptide binding]; other site
866346003734	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
866346003735	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
866346003736	active site
866346003737	(T/H)XGH motif; other site
866346003738	nickel responsive regulator; Provisional; Region: PRK00630
866346003739	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
866346003740	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
866346003741	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
866346003742	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
866346003743	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
866346003744	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
866346003745	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
866346003746	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346003747	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866346003748	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957
866346003749	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
866346003750	Acylphosphatase; Region: Acylphosphatase; pfam00708
866346003751	[NiFe] hydrogenase maturation protein HypF; Region: hypF; TIGR00143
866346003752	HypF finger; Region: zf-HYPF; pfam07503
866346003753	HypF finger; Region: zf-HYPF; pfam07503
866346003754	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
866346003755	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
866346003756	dimerization interface [polypeptide binding]; other site
866346003757	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
866346003758	ATP binding site [chemical binding]; other site
866346003759	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
866346003760	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
866346003761	NADP binding site [chemical binding]; other site
866346003762	active site
866346003763	putative substrate binding site [chemical binding]; other site
866346003764	GDP-mannose 4,6-dehydratase; Region: gmd; TIGR01472
866346003765	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
866346003766	NADP-binding site; other site
866346003767	homotetramer interface [polypeptide binding]; other site
866346003768	substrate binding site [chemical binding]; other site
866346003769	homodimer interface [polypeptide binding]; other site
866346003770	active site
866346003771	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
866346003772	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
866346003773	Substrate binding site; other site
866346003774	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
866346003775	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
866346003776	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
866346003777	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
866346003778	VirB7 interaction site; other site
866346003779	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
866346003780	Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; Region: TrbL; COG3846
866346003781	PDZ domain; Region: PDZ_2; pfam13180
866346003782	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
866346003783	hypothetical protein; Provisional; Region: PRK03762
866346003784	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
866346003785	tetramerization interface [polypeptide binding]; other site
866346003786	active site
866346003787	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
866346003788	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346003789	Walker A motif; other site
866346003790	ATP binding site [chemical binding]; other site
866346003791	Walker B motif; other site
866346003792	arginine finger; other site
866346003793	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346003794	Walker A motif; other site
866346003795	ATP binding site [chemical binding]; other site
866346003796	Walker B motif; other site
866346003797	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
866346003798	Uncharacterized conserved protein [Function unknown]; Region: COG2127
866346003799	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
866346003800	Ligand Binding Site [chemical binding]; other site
866346003801	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
866346003802	AAA domain; Region: AAA_26; pfam13500
866346003803	Protein of unknown function (DUF1523); Region: DUF1523; pfam07509
866346003804	isocitrate dehydrogenase; Validated; Region: PRK07362
866346003805	isocitrate dehydrogenase; Reviewed; Region: PRK07006
866346003806	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
866346003807	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
866346003808	dimer interface [polypeptide binding]; other site
866346003809	active site
866346003810	citrylCoA binding site [chemical binding]; other site
866346003811	NADH binding [chemical binding]; other site
866346003812	cationic pore residues; other site
866346003813	oxalacetate/citrate binding site [chemical binding]; other site
866346003814	coenzyme A binding site [chemical binding]; other site
866346003815	catalytic triad [active]
866346003816	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cl00089
866346003817	Type III restriction/modification enzyme methylation subunit; Region: TypeIII_RM_meth; pfam12564
866346003818	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
866346003819	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346003820	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346003821	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3421
866346003822	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
866346003823	ATP binding site [chemical binding]; other site
866346003824	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
866346003825	putative Mg++ binding site [ion binding]; other site
866346003826	biotin synthase; Provisional; Region: PRK08508
866346003827	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866346003828	FeS/SAM binding site; other site
866346003829	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
866346003830	YihY family inner membrane protein; Region: yihY_not_rbn; TIGR00765
866346003831	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866346003832	Protein of unknown function DUF262; Region: DUF262; pfam03235
866346003833	Protein of unknown function DUF262; Region: DUF262; pfam03235
866346003834	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866346003835	7-cyano-7-deazaguanine reductase; Region: QueF-II; TIGR03139
866346003836	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
866346003837	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
866346003838	tRNA dimethylallyltransferase; Region: miaA; TIGR00174
866346003839	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
866346003840	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
866346003841	Ligand binding site; other site
866346003842	metal-binding site
866346003843	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
866346003844	Sulfatase; Region: Sulfatase; pfam00884
866346003845	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13904
866346003846	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
866346003847	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
866346003848	flagellum-specific ATP synthase; Validated; Region: fliI; PRK08472
866346003849	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
866346003850	Walker A motif/ATP binding site; other site
866346003851	Walker B motif; other site
866346003852	Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis [Cell motility and secretion / Intracellular trafficking and secretion]; Region: VirB11; COG0630
866346003853	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
866346003854	ATP binding site [chemical binding]; other site
866346003855	Walker A motif; other site
866346003856	hexamer interface [polypeptide binding]; other site
866346003857	Walker B motif; other site
866346003858	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
866346003859	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
866346003860	active site
866346003861	HIGH motif; other site
866346003862	nucleotide binding site [chemical binding]; other site
866346003863	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
866346003864	active site
866346003865	KMSKS motif; other site
866346003866	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
866346003867	tRNA binding surface [nucleotide binding]; other site
866346003868	anticodon binding site; other site
866346003869	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866346003870	RNA binding surface [nucleotide binding]; other site
866346003871	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14462
866346003872	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866346003873	FeS/SAM binding site; other site
866346003874	KpsF/GutQ family protein; Region: kpsF; TIGR00393
866346003875	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
866346003876	putative active site [active]
866346003877	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
866346003878	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
866346003879	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
866346003880	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
866346003881	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
866346003882	dimethyladenosine transferase; Region: ksgA; TIGR00755
866346003883	S-adenosylmethionine binding site [chemical binding]; other site
866346003884	formyltetrahydrofolate deformylase; Region: PurU; TIGR00655
866346003885	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
866346003886	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
866346003887	active site
866346003888	substrate binding site [chemical binding]; other site
866346003889	cosubstrate binding site; other site
866346003890	catalytic site [active]
866346003891	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
866346003892	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
866346003893	tandem repeat interface [polypeptide binding]; other site
866346003894	oligomer interface [polypeptide binding]; other site
866346003895	active site residues [active]
866346003896	TIR domain; Region: TIR_2; pfam13676
866346003897	potential frameshift: common BLAST hit: gi|15646047|ref|NP_208229.1| lipoprotein
866346003898	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
866346003899	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
866346003900	active site
866346003901	carbon storage regulator; Provisional; Region: PRK00568
866346003902	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK04181
866346003903	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
866346003904	SmpB-tmRNA interface; other site
866346003905	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; pfam01618
866346003906	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
866346003907	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
866346003908	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
866346003909	ribonuclease P protein component, eubacterial; Region: rnpA; TIGR00188
866346003910	hypothetical protein; Provisional; Region: PRK14374
866346003911	membrane protein insertase; Provisional; Region: PRK01318
866346003912	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
866346003913	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
866346003914	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
866346003915	tRNA modification GTPase TrmE; Region: mnmE_trmE_thdF; TIGR00450
866346003916	trmE is a tRNA modification GTPase; Region: trmE; cd04164
866346003917	G1 box; other site
866346003918	GTP/Mg2+ binding site [chemical binding]; other site
866346003919	Switch I region; other site
866346003920	G2 box; other site
866346003921	Switch II region; other site
866346003922	G3 box; other site
866346003923	G4 box; other site
866346003924	G5 box; other site
866346003925	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
866346003926	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346003927	LPP20 lipoprotein; Region: LPP20; pfam02169
866346003928	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
866346003929	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
866346003930	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
866346003931	catalytic residues [active]
866346003932	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
866346003933	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866346003934	RNA binding surface [nucleotide binding]; other site
866346003935	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
866346003936	active site
866346003937	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
866346003938	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
866346003939	active site
866346003940	PHP Thumb interface [polypeptide binding]; other site
866346003941	metal binding site [ion binding]; metal-binding site
866346003942	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
866346003943	generic binding surface I; other site
866346003944	generic binding surface II; other site
866346003945	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
866346003946	Heat shock protein [Posttranslational modification, protein turnover, chaperones]; Region: HslJ; COG3187
866346003947	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
866346003948	mce related protein; Region: MCE; pfam02470
866346003949	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
866346003950	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
866346003951	Walker A/P-loop; other site
866346003952	ATP binding site [chemical binding]; other site
866346003953	Q-loop/lid; other site
866346003954	ABC transporter signature motif; other site
866346003955	Walker B; other site
866346003956	D-loop; other site
866346003957	H-loop/switch region; other site
866346003958	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
866346003959	conserved hypothetical integral membrane protein; Region: TIGR00056
866346003960	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346003961	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
866346003962	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
866346003963	homodimer interface [polypeptide binding]; other site
866346003964	substrate-cofactor binding pocket; other site
866346003965	catalytic residue [active]
866346003966	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346003967	DNA polymerase I; Region: pola; TIGR00593
866346003968	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
866346003969	active site
866346003970	metal binding site 1 [ion binding]; metal-binding site
866346003971	putative 5' ssDNA interaction site; other site
866346003972	metal binding site 3; metal-binding site
866346003973	metal binding site 2 [ion binding]; metal-binding site
866346003974	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
866346003975	putative DNA binding site [nucleotide binding]; other site
866346003976	putative metal binding site [ion binding]; other site
866346003977	3'-5' exonuclease; Region: 35EXOc; smart00474
866346003978	active site
866346003979	substrate binding site [chemical binding]; other site
866346003980	catalytic site [active]
866346003981	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
866346003982	active site
866346003983	DNA binding site [nucleotide binding]
866346003984	catalytic site [active]
866346003985	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866346003986	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866346003987	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
866346003988	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
866346003989	thymidylate kinase; Validated; Region: tmk; PRK00698
866346003990	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
866346003991	TMP-binding site; other site
866346003992	ATP-binding site [chemical binding]; other site
866346003993	Phosphopantetheine adenylyltransferase [Coenzyme metabolism]; Region: CoaD; COG0669
866346003994	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
866346003995	active site
866346003996	(T/H)XGH motif; other site
866346003997	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
866346003998	Flavoprotein; Region: Flavoprotein; pfam02441
866346003999	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK08515
866346004000	flagella basal body P-ring formation protein FlgA; Region: flgA_cterm; TIGR03170
866346004001	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
866346004002	Part of AAA domain; Region: AAA_19; pfam13245
866346004003	Family description; Region: UvrD_C_2; pfam13538
866346004004	TPR repeat; Region: TPR_11; pfam13414
866346004005	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866346004006	TPR motif; other site
866346004007	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866346004008	binding surface
866346004009	TPR motif; other site
866346004010	seryl-tRNA synthetase; Provisional; Region: PRK05431
866346004011	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
866346004012	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
866346004013	dimer interface [polypeptide binding]; other site
866346004014	active site
866346004015	motif 1; other site
866346004016	motif 2; other site
866346004017	motif 3; other site
866346004018	Predicted amidohydrolase [General function prediction only]; Region: COG0388
866346004019	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
866346004020	active site
866346004021	catalytic triad [active]
866346004022	dimer interface [polypeptide binding]; other site
866346004023	Exonuclease VII small subunit; Region: Exonuc_VII_S; cl00750
866346004024	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
866346004025	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866346004026	S-adenosylmethionine binding site [chemical binding]; other site
866346004027	Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863
866346004028	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
866346004029	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
866346004030	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
866346004031	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
866346004032	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
866346004033	ABC-2 type transporter; Region: ABC2_membrane; cl17235
866346004034	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866346004035	HlyD family secretion protein; Region: HlyD_3; pfam13437
866346004036	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
866346004037	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
866346004038	Domain of unknown function DUF21; Region: DUF21; pfam01595
866346004039	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
866346004040	Transporter associated domain; Region: CorC_HlyC; smart01091
866346004041	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
866346004042	Phosphate transporter family; Region: PHO4; pfam01384
866346004043	NifU-like domain; Region: NifU; pfam01106
866346004044	UDP-N-acetylmuramyl-tripeptide synthetase; Region: murE; TIGR01085
866346004045	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866346004046	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866346004047	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
866346004048	putative active site [active]
866346004049	transaldolase; Provisional; Region: PRK03903
866346004050	catalytic residue [active]
866346004051	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
866346004052	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
866346004053	5S rRNA interface [nucleotide binding]; other site
866346004054	CTC domain interface [polypeptide binding]; other site
866346004055	L16 interface [polypeptide binding]; other site
866346004056	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
866346004057	putative active site [active]
866346004058	catalytic residue [active]
866346004059	Predicted permeases [General function prediction only]; Region: COG0795
866346004060	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
866346004061	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
866346004062	catalytic site [active]
866346004063	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
866346004064	Uncharacterized conserved protein (DUF2161); Region: DUF2161; cl02298
866346004065	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346004066	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3399
866346004067	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
866346004068	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
866346004069	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
866346004070	metal-binding site [ion binding]
866346004071	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
866346004072	Soluble P-type ATPase [General function prediction only]; Region: COG4087
866346004073	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
866346004074	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866346004075	S-adenosylmethionine binding site [chemical binding]; other site
866346004076	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
866346004077	catalytic motif [active]
866346004078	Zn binding site [ion binding]; other site
866346004079	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
866346004080	RibD C-terminal domain; Region: RibD_C; cl17279
866346004081	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
866346004082	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
866346004083	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
866346004084	NAD(P) binding pocket [chemical binding]; other site
866346004085	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
866346004086	4Fe-4S binding domain; Region: Fer4_5; pfam12801
866346004087	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
866346004088	acyl-phosphate glycerol 3-phosphate acyltransferase; Region: TIGR00023
866346004089	FolB domain; Region: folB_dom; TIGR00526
866346004090	active site
866346004091	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
866346004092	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866346004093	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866346004094	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
866346004095	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
866346004096	transcription elongation factor NusA; Provisional; Region: nusA; PRK12328
866346004097	NusA N-terminal domain; Region: NusA_N; pfam08529
866346004098	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
866346004099	RNA binding site [nucleotide binding]; other site
866346004100	homodimer interface [polypeptide binding]; other site
866346004101	NusA-like KH domain; Region: KH_5; pfam13184
866346004102	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
866346004103	G-X-X-G motif; other site
866346004104	potential frameshift: common BLAST hit: gi|254780026|ref|YP_003058133.1| type IIS restriction-modification protein
866346004105	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
866346004106	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
866346004107	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
866346004108	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
866346004109	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
866346004110	ABC transporter signature motif; other site
866346004111	Walker B; other site
866346004112	D-loop; other site
866346004113	H-loop/switch region; other site
866346004114	Restriction endonuclease [Defense mechanisms]; Region: COG3587
866346004115	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866346004116	ATP binding site [chemical binding]; other site
866346004117	putative Mg++ binding site [ion binding]; other site
866346004118	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
866346004119	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
866346004120	DNA methylase; Region: N6_N4_Mtase; cl17433
866346004121	DNA methylase; Region: N6_N4_Mtase; pfam01555
866346004122	DNA methylase; Region: N6_N4_Mtase; cl17433
866346004123	ATP-dependent DNA helicase RecG; Region: recG; TIGR00643
866346004124	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
866346004125	ssDNA binding site; other site
866346004126	generic binding surface II; other site
866346004127	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866346004128	ATP binding site [chemical binding]; other site
866346004129	putative Mg++ binding site [ion binding]; other site
866346004130	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866346004131	nucleotide binding region [chemical binding]; other site
866346004132	ATP-binding site [chemical binding]; other site
866346004133	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346004134	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
866346004135	active site
866346004136	putative catalytic site [active]
866346004137	DNA binding site [nucleotide binding]
866346004138	putative phosphate binding site [ion binding]; other site
866346004139	metal binding site A [ion binding]; metal-binding site
866346004140	AP binding site [nucleotide binding]; other site
866346004141	metal binding site B [ion binding]; metal-binding site
866346004142	Protein interacting with poly(A)-binding protein [RNA processing and modification]; Region: PBP1; COG5180
866346004143	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
866346004144	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866346004145	Walker A motif; other site
866346004146	ATP binding site [chemical binding]; other site
866346004147	Walker B motif; other site
866346004148	arginine finger; other site
866346004149	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
866346004150	DnaA box-binding interface [nucleotide binding]; other site
866346004151	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
866346004152	Protein of unknown function (DUF2443); Region: DUF2443; pfam10398
866346004153	glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Region: glmS; TIGR01135
866346004154	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
866346004155	glutaminase active site [active]
866346004156	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
866346004157	dimer interface [polypeptide binding]; other site
866346004158	active site
866346004159	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
866346004160	dimer interface [polypeptide binding]; other site
866346004161	active site
866346004162	Predicted alternative thymidylate synthase [Nucleotide transport and metabolism]; Region: THY1; COG1351
866346004163	bifunctional D-alanyl-alanine synthetase A/UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: PRK14573
866346004164	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
866346004165	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
866346004166	HsdM N-terminal domain; Region: HsdM_N; pfam12161
866346004167	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
866346004168	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
866346004169	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
866346004170	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866346004171	ATP binding site [chemical binding]; other site
866346004172	putative Mg++ binding site [ion binding]; other site
866346004173	Protein of unknown function DUF45; Region: DUF45; pfam01863
866346004174	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
866346004175	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
866346004176	N-terminal plug; other site
866346004177	ligand-binding site [chemical binding]; other site
866346004178	Arginase family; Region: Arginase; cd09989
866346004179	active site
866346004180	Mn binding site [ion binding]; other site
866346004181	oligomer interface [polypeptide binding]; other site
866346004182	potential frameshift: common BLAST hit: gi|308183641|ref|YP_003927768.1| amino acid permease
866346004183	Amino acid transporters [Amino acid transport and metabolism]; Region: LysP; COG0833
866346004184	Amino acid transporters [Amino acid transport and metabolism]; Region: LysP; COG0833
866346004185	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
866346004186	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
866346004187	hexamer interface [polypeptide binding]; other site
866346004188	ligand binding site [chemical binding]; other site
866346004189	putative active site [active]
866346004190	NAD(P) binding site [chemical binding]; other site
866346004191	Protein of unknown function DUF262; Region: DUF262; pfam03235
866346004192	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866346004193	Protein of unknown function DUF262; Region: DUF262; pfam03235
866346004194	Uncharacterized conserved protein [Function unknown]; Region: COG1479
866346004195	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
866346004196	Helicobacter outer membrane protein; Region: HP_OMP; pfam01856
866346004197	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
866346004198	ATP-NAD kinase; Region: NAD_kinase; pfam01513
866346004199	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
866346004200	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866346004201	Walker A/P-loop; other site
866346004202	ATP binding site [chemical binding]; other site
866346004203	Q-loop/lid; other site
866346004204	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
866346004205	ABC transporter signature motif; other site
866346004206	Walker B; other site
866346004207	D-loop; other site
866346004208	H-loop/switch region; other site
866346004209	Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293
866346004210	Domain of unknown function (DUF814); Region: DUF814; pfam05670
866346004211	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866346004212	DNA polymerase III subunit epsilon; Provisional; Region: PRK08517
866346004213	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
866346004214	active site
866346004215	catalytic site [active]
866346004216	substrate binding site [chemical binding]; other site
866346004217	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
866346004218	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
866346004219	substrate binding site [chemical binding]; other site
866346004220	hexamer interface [polypeptide binding]; other site
866346004221	metal binding site [ion binding]; metal-binding site
866346004222	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
866346004223	active site
866346004224	Methyltransferase domain; Region: Methyltransf_26; pfam13659
866346004225	elongation factor Ts; Provisional; Region: tsf; PRK09377
866346004226	UBA/TS-N domain; Region: UBA; pfam00627
866346004227	Elongation factor TS; Region: EF_TS; pfam00889
866346004228	Elongation factor TS; Region: EF_TS; pfam00889
866346004229	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
866346004230	rRNA interaction site [nucleotide binding]; other site
866346004231	S8 interaction site; other site
866346004232	putative laminin-1 binding site; other site
866346004233	putative recombination protein RecB; Provisional; Region: PRK13909
866346004234	Family description; Region: UvrD_C_2; pfam13538
866346004235	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
866346004236	pH-dependent sodium/proton antiporter; Provisional; Region: nhaA; PRK14856
866346004237	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
866346004238	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
866346004239	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
866346004240	protein-export membrane protein SecF; Region: 3a0501s07; TIGR00966
866346004241	Protein export membrane protein; Region: SecD_SecF; pfam02355
866346004242	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
866346004243	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
866346004244	HIGH motif; other site
866346004245	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
866346004246	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
866346004247	active site
866346004248	KMSKS motif; other site
866346004249	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
866346004250	tRNA binding surface [nucleotide binding]; other site
866346004251	anticodon binding site; other site
866346004252	Lipopolysaccharide-assembly; Region: LptE; pfam04390
866346004253	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
866346004254	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866346004255	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866346004256	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
866346004257	Peptidase family M23; Region: Peptidase_M23; pfam01551
866346004258	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
866346004259	Peptidase family M23; Region: Peptidase_M23; pfam01551
866346004260	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
866346004261	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
866346004262	transcription-repair coupling factor (mfd); Region: mfd; TIGR00580
866346004263	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
866346004264	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866346004265	ATP binding site [chemical binding]; other site
866346004266	putative Mg++ binding site [ion binding]; other site
866346004267	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866346004268	nucleotide binding region [chemical binding]; other site
866346004269	ATP-binding site [chemical binding]; other site
866346004270	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
866346004271	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
866346004272	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
866346004273	iron-sulfur cluster [ion binding]; other site
866346004274	[2Fe-2S] cluster binding site [ion binding]; other site
866346004275	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
866346004276	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
866346004277	intrachain domain interface; other site
866346004278	interchain domain interface [polypeptide binding]; other site
866346004279	heme bH binding site [chemical binding]; other site
866346004280	Qi binding site; other site
866346004281	heme bL binding site [chemical binding]; other site
866346004282	Qo binding site; other site
866346004283	interchain domain interface [polypeptide binding]; other site
866346004284	intrachain domain interface; other site
866346004285	Qi binding site; other site
866346004286	Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032
866346004287	Qo binding site; other site
866346004288	Cytochrome c1 [Energy production and conversion]; Region: CYT1; COG2857
866346004289	Cytochrome c; Region: Cytochrom_C; pfam00034
866346004290	Cytochrome c; Region: Cytochrom_C; cl11414
866346004291	Predicted ATPases [General function prediction only]; Region: COG1106
866346004292	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866346004293	Walker A/P-loop; other site
866346004294	ATP binding site [chemical binding]; other site
866346004295	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
866346004296	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
866346004297	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
866346004298	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK03907
866346004299	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
866346004300	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
866346004301	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
866346004302	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
866346004303	Cell cycle protein; Region: FTSW_RODA_SPOVE; pfam01098
866346004304	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
866346004305	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
866346004306	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
866346004307	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
866346004308	dimer interface [polypeptide binding]; other site
866346004309	decamer (pentamer of dimers) interface [polypeptide binding]; other site
866346004310	catalytic triad [active]
866346004311	peroxidatic and resolving cysteines [active]
866346004312	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
866346004313	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
866346004314	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
866346004315	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
866346004316	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
866346004317	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
866346004318	G1 box; other site
866346004319	GTP/Mg2+ binding site [chemical binding]; other site
866346004320	Switch I region; other site
866346004321	G2 box; other site
866346004322	G3 box; other site
866346004323	Switch II region; other site
866346004324	G4 box; other site
866346004325	G5 box; other site
866346004326	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
866346004327	OstA-like protein; Region: OstA; pfam03968
866346004328	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
866346004329	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866346004330	active site
866346004331	motif I; other site
866346004332	motif II; other site
866346004333	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
866346004334	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
866346004335	Sporulation related domain; Region: SPOR; pfam05036
866346004336	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
866346004337	N-acetyl-D-glucosamine binding site [chemical binding]; other site
866346004338	catalytic residue [active]
866346004339	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
866346004340	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
866346004341	active site
866346004342	riboflavin synthase, alpha subunit; Region: ribE; TIGR00187
866346004343	Lumazine binding domain; Region: Lum_binding; pfam00677
866346004344	Lumazine binding domain; Region: Lum_binding; pfam00677
866346004345	flhB C-terminus-related protein; Region: flhB_rel; TIGR00789
866346004346	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
866346004347	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
866346004348	Walker A/P-loop; other site
866346004349	ATP binding site [chemical binding]; other site
866346004350	Q-loop/lid; other site
866346004351	ABC transporter signature motif; other site
866346004352	Walker B; other site
866346004353	D-loop; other site
866346004354	H-loop/switch region; other site
866346004355	NIL domain; Region: NIL; pfam09383
866346004356	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
866346004357	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
866346004358	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
866346004359	active site
866346004360	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
866346004361	This subfamily is composed of uncharacterized bacterial glycosyltransferases in the MraY-like family. This family contains both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases, which...; Region: GT_MraY_like; cd06912
866346004362	Mg++ binding site [ion binding]; other site
866346004363	putative catalytic motif [active]
866346004364	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
866346004365	active site
866346004366	hydrophilic channel; other site
866346004367	dimerization interface [polypeptide binding]; other site
866346004368	catalytic residues [active]
866346004369	active site lid [active]
866346004370	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
866346004371	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK03946
866346004372	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
866346004373	metallohydrolase, glycoprotease/Kae1 family; Region: gcp_kae1; TIGR00329
866346004374	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
866346004375	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
866346004376	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
866346004377	hypothetical protein; Provisional; Region: PRK10236
866346004378	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
866346004379	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735